MH - 2019-nCoV Vaccine mRNA-1273 UI - D000090983 MN - D12.776.828.868.228.500.500 MN - D20.215.894.865.450.500.500 MN - D20.215.894.899.85.250 MN - D23.50.865.450.500.500 MS - mRNA vaccine against SARS-CoV-2 developed by Moderna. HN - 2022(2021) BX - COVID-19 Vaccine Moderna BX - mRNA-1273 MH - Abdominal Core UI - D000090043 MN - A1.923.112 MS - The torso region located deep within the abdominal area involved in attaching the TORSO to the SPINE and the PELVIC FLOOR. Muscles in the abdominal core are important in POSTURAL BALANCE, spine stability and protection against BACK INJURIES. HN - 2022 MH - Access to Healthy Foods UI - D000091483 MN - J1.576.423.750.688.500 MN - J1.576.423.750.875.500 MS - Convenient availability to affordable foods that support healthy eating patterns. Access may be limited due to having a limited income or living far away from sources of healthful and affordable food. HN - 2022 BX - Access to Health Food BX - Healthy Food Availability MH - Ad26COVS1 UI - D000090984 MN - D20.215.894.899.85.125 MS - A viral vector vaccine designed against SARS-CoV-2 developed by Johnson & Johnson. Its vector encodes the SARS-CoV-2 Spike protein. HN - 2022 BX - COVID-19 Vaccine Johnson & Johnson MH - Adjuvants, Vaccine UI - D000089582 MN - D26.650.64.500 MN - D27.505.696.477.67.500 MN - D27.720.744.64.500 MS - Substances consist of different components, e.g. aluminum salts, EMULSIONS such as MF59 and AS03, Toll-like receptor (TLR) agonist or combinations of IMMUNOPOTENTIATORS (QS-21 and MPL in AS01), that helps increase the magnitude of an ADAPTIVE IMMUNE RESPONSE to a VACCINE. HN - 2022 BX - Vaccine Adjuvant BX - Vaccine Adjuvants MH - Adolescent Fathers UI - D000089122 MN - F1.829.263.500.320.100.500 MN - I1.880.853.150.500.340.210.500 MN - M1.620.390.500 MS - Fathers initially aged less than 19 years at the time of child's birth. HN - 2022 BX - Adolescent Fatherhood BX - Teen Fathers BX - Teenage Fathers BX - Teenager Fathers FX - Pregnancy in Adolescence MH - Adolescent Mothers UI - D000088662 MN - M1.620.630.100 MS - Mothers aged less than 19 years at the time of child's conception or birth. HN - 2022 BX - Adolescent Motherhood BX - Teen Mothers BX - Teenage Mothers FX - Pregnancy in Adolescence MH - ADP-Ribosylation Factor 6 UI - D000089982 MN - D8.811.277.40.330.300.400.100.50 MN - D12.776.157.325.515.100.550 MN - D12.776.476.338.400.100.50 MS - A member of GTP-binding protein of the large ras superfamily involved in regulation of membrane trafficking by modulating ENDOCYTOSIS and ACTIN CYTOSKELETON remodeling. HN - 2022 BX - ADP Ribosylation Factor 6 BX - ARF6 Protein MH - Aerosolized Particles and Droplets UI - D000088342 MN - D20.65 MS - A suspension of tiny particles or liquid droplets (< 5-10 microns) in the air. They sometimes cause adverse health effects when inhaled or absorbed. HN - 2022 BX - Aerosolized Droplets BX - Aerosolized Droplets and Particles BX - Aerosolized Particles BX - Droplet Nuclei BX - Spray Aerosol FX - Aerosols MH - Afrotheria UI - D000091122 MN - B1.50.150.900.649.313.250 MS - A placental mammal superorder that contains ELEPHANTS; MANATEES; DUGONGS; SIRENIANS; HYRAXES; AARDVARKS; elephant shrews (Macroscelidea); TENRECS; Golden moles (Chrysochloridae). Largely classified based on DNA sequence afrotherian mammals are diverse in morphology but share some common anatomical features (e.g., appearance of four‐lobed ALLANTOIS and long and mobile snout). HN - 2022 BX - Afrotheres BX - Afrotherian Mammals BX - Chrysochloridae BX - Elephant Shrews BX - Golden Moles BX - Macroscelidea MH - Ambulatory Care Sensitive Conditions UI - D000090004 MN - C23.550.291.156 MN - E5.318.308.980.438.475.183 MN - N5.715.360.300.800.438.375.46 MN - N6.850.520.308.980.438.475.12 MS - Various health conditions in OUTPATIENT CARE settings for which adequate management, treatment and interventions delivered in the ambulatory care setting could potentially prevent HOSPITALIZATION. HN - 2022 FX - Quality of Health Care MH - AMP-Activated Protein Kinase Kinases UI - D000091162 MN - D8.811.913.696.620.682.700.74 MN - D12.776.476.563.74 MS - Protein Serine-threonine kinases that phosphorylate the 63-kDa subunit of AMP-ACTIVATED PROTEIN KINASES. This action results in reactivation of AMP-ACTIVATED PROTEIN KINASE activity and downstream signaling aimed at decreased metabolism. HN - 2022(1994) BX - AMP-PK Reactivator BX - AMP-PK Reactivators BX - AMPK Kinase MH - Anaerobic Ammonia Oxidation UI - D000090642 MN - G2.111.587.125 MN - G2.607.560.125 MN - G16.500.768.125 MS - A process facilitated by specialized bacteria (PLANCTOMYCETES) involving the oxidation of ammonia to gaseous nitrogen by using nitrite as the electron acceptor. HN - 2022 BX - Anammox MH - Andrographis paniculata UI - D000089002 MN - B1.875.800.575.912.250.583.40.44.500 MS - A plant species in the genus Andrographis, family Acanthaceae. Its bitter tasting leaves have been used in traditional medicine and contain labdane-type diterpene lactone andrographolide. HN - 2022 BX - Chirata MH - Angiomotins UI - D000091082 MN - D12.644.360.24.82 MN - D12.776.476.24.87 MS - A class of intracellular signaling proteins that were originally identified as inhibitors of ANGIOSTATIN activity. They play a role in cell signaling pathways such as those involving G-PROTEINS and the HIPPO-SIGNALING PATHWAY. HN - 2022 BX - Angiomotin BX - Angiomotin-Like Proteins MH - Angiopoietin-Like Protein 1 UI - D000091304 MN - D12.644.276.100.50.100 MN - D12.776.467.100.50.100 MN - D23.529.100.50.100 MS - The first member of the Angiopoietin-like protein family to be discovered. It is considered a key endogenous ANTIANGIOGENIC AGENT which inhibits the proliferation, migration, tube formation, and adhesion of ENDOTHELIAL CELLS. HN - 2022 BX - Angioarrestin MH - Angiopoietin-Like Protein 2 UI - D000091302 MN - D12.644.276.100.50.200 MN - D12.776.467.100.50.200 MN - D23.529.100.50.200 MS - A circulating angiopoietin-like protein that is expressed in a variety of tissues in response to HYPOXIA. It acts by inducing angiogenesis and endothelial cell migration. HN - 2022 BX - Angiopoietin-Related Protein 2 MH - Angiopoietin-Like Protein 3 UI - D000091303 MN - D12.644.276.100.50.300 MN - D12.776.467.100.50.300 MN - D23.529.100.50.300 MS - An angiopoietin-like protein that plays a role in regulation of LIPOPROTEIN metabolism. HN - 2022 MH - Angiopoietin-Like Protein 6 UI - D000091308 MN - D12.644.276.100.50.600 MN - D12.776.467.100.50.600 MN - D23.529.100.50.550 MS - An angiopoietin-like protein that is expressed in LIVER and involved in regulation of BLOOD GLUCOSE; LIPID METABOLISM; and ENERGY METABOLISM. HN - 2022 BX - Angiopoietin-Related Protein 5 MH - Angiopoietin-Like Protein 7 UI - D000091307 MN - D12.644.276.100.50.700 MN - D12.776.467.100.50.700 MN - D23.529.100.50.700 MS - An angiopoietin-like protein that is expressed in NERVE TISSUE, KERATOCONUS corneas, TRABECULAR MESHWORK. HN - 2022 MH - Angiopoietin-Like Protein 8 UI - D000091306 MN - D12.644.276.100.50.800 MN - D12.776.467.100.50.800 MN - D23.529.100.50.800 MS - A nutritionally-regulated factor found in the LIVER. It plays a role in lipid metabolism and VLDL secretion in the liver. It was originally called betatrophin due to its suspected role as a peptide hormone that stimulates beta cell proliferation. HN - 2022 BX - Betatrophin MH - Anthropogenic Effects UI - D000087602 MN - G16.500.75 MS - Environmental alterations resulting from human activities. HN - 2022 BX - Anthropogenic Activities BX - Anthropogenic Disturbance BX - Anthropogenic Effect BX - Anthropogenic Factors BX - Anthropogenic Impact BX - Anthropogenic Impacts BX - Anthropogenic Pressure BX - Anthropogenic Pressures BX - Anthropogenic Stressor BX - Anthropogenic Stressors BX - Human Impact BX - Human Impacts MH - Anticoagulant Reversal Agents UI - D000089964 MN - D27.505.954.502.270.463.46 MS - Agents that have the potential to reverse specific anticoagulation therapies. HN - 2022 BX - Anticoagulant Reversal Drugs BX - Anticoagulation Reversal Agents BX - Antithrombotic Reversal Agents FX - Antidotes MH - Anticoagulation Reversal UI - D000088542 MN - E2.520.45 MS - Treatment strategies used to manage bleeding events that occur during the use of ANTICOAGULANTS. HN - 2022 BX - Anticoagulant Reversal BX - Reversal of Anticoagulation MH - Antifibrotic Agents UI - D000088962 MN - D27.505.954.158.273 MS - These agents are used to reduce FIBROSIS affecting organs and formation of scar TISSUES such as in SCLERODERMA patients. HN - 2022 BX - Anti-Fibrotic Agents MH - Antigenic Drift and Shift UI - D000088603 MN - G5.45.300.500 MN - G5.330.320.500 MN - G5.365.73.500 MN - G12.500.249.500 MN - G16.75.300.500 MS - Changes in the ANTIGEN population by slow and minor (antigenic drift) or sudden and major mutations (antigenic shift). Accumulation of minor mutations in antigenic drift over time may require development of new vaccine (e.g., seasonal FLU VACCINES). Antigenic shift on the other hand is less common but may result in emergence of a new subtype or species and sometimes pandemics (e.g., H1N1 pandemics in 2009 and 2018 and COVID-19) due to lack of HERD IMMUNITY to the newly emerged novel pathogen. HN - 2022 BX - Antigen Drift BX - Antigen Drift and Shift BX - Antigen Escape BX - Antigen Shift BX - Antigen Shift and Drift BX - Antigenic Drift BX - Antigenic Escape BX - Antigenic Shift BX - Antigenic Shift and Drift MH - Antiglaucoma Agents UI - D000089502 MN - D27.505.954.69 MS - Agents used to preserve visual function by decreasing INTRAOCULAR PRESSURE (IOP) by targeting the AQUEOUS HUMOR. HN - 2022 BX - Anti-Glaucoma Agent BX - Anti-Glaucoma Agents BX - Anti-Glaucoma Drug BX - Anti-Glaucoma Drugs BX - Anti-Glaucoma Medications BX - Antiglaucoma Drugs BX - Antiglaucoma Medications MH - Antimicrobial Peptides UI - D000089882 MN - D12.644.66 MS - Small peptides that play an important role in early innate and induced defenses against invading microbes. Most have positive overall charges and are referred to as cationic antimicrobial peptides. HN - 2022(2021) BX - Antimicrobial Peptide MH - Antiviral Restriction Factors UI - D000090103 MN - D12.776.66 MS - A broad category of endogenous host cellular factors upregulated in response to pathogens (i.e., INTERFERON-stimulated genes) and recruited to interfere with VIRAL REPLICATION and/or trigger host antiviral CELLULAR IMMUNE RESPONSE. HN - 2022 BX - Antiviral Effectors BX - Cellular Restriction Factors BX - Host Cell Restriction Factors BX - Restriction Factors, Antiviral MH - Aquatic Therapy UI - D000088543 MN - E2.779.492.250 MN - E2.831.535.492.250 MS - Physical therapy administered while the body is immersed in an aquatic environment. HN - 2022 BX - Ai Chi Therapy BX - Aquatic Exercise Therapy BX - Pool Therapy BX - Water Exercise Therapy BX - Water Tai Chi Therapy FX - Balneology MH - Artificial Virus-Like Particles UI - D000087511 MN - A21.63 MS - Artificially prepared viral sub-particles devoid of viral genetic material. They are often formed by self-assembly of exogenously expressed viral proteins and are often used for a vaccine development, cell expression and bioprocessing platforms. HN - 2022 BX - Artificial Virus BX - Artificial VLP BX - Artificial VLP Virus-Like Particles MH - Autonomous Vehicles UI - D000088684 MN - J1.937.500.300 MS - Vehicles controlled by automatic directions and instructions. AN - self-driving cars: coordinate with AUTOMOBILES HN - 2022 BX - Automated Vehicles BX - Driverless Vehicles BX - Self-Controlled Vehicles BX - Self-Driving Cars BX - Self-Driving Vehicles MH - Axial Spondyloarthritis UI - D000089183 MN - C5.116.900.853.625.800.744 MN - C5.550.69.340 MN - C5.550.114.865.800.744 MS - A spectrum of chronic inflammatory conditions affecting the axial joints (e.g., SPINE), characterized by pain, stiffness of joints (ANKYLOSIS), reduced mobility and inflammation. When joint inflammation and damage are visible on regular X-rays it is called ANKYLOSING SPONDYLITIS; otherwise it is referred to as NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS. HLA-B27 ANTIGEN is a biomarker and IL-23/IL-17 pathway a potential therapeutic target for axial and other related spondyloarthritis. AN - general or unspecified; prefer specifics HN - 2022 BX - AxSpA MH - Besnoitia UI - D000089963 MN - B1.43.75.189.250.750.275 MS - An apicomplexan parasitic genus of the family SARCOCYSTIDAE. Infection by Besnoitia is BESNOITIASIS. HN - 2022(1992) FX - Coccidiosis MH - Bias, Implicit UI - D000087302 MN - F1.145.813.550.281 MN - F1.829.595.312 MS - The attitudes or stereotypes that affect understanding, actions, and decisions in an unconscious manner. These biases which include favorable and unfavorable assessments, are activated involuntarily without individual's intentional control. (from https://www.jointcommission.org/-/media/deprecated-unorganized/imported-assets/tjc/system-folders/joint-commission-online/quick_safety_issue_23_apr_2016pdf.pdf?db=web&hash=A5852411BCA02D1A918284EBAA775988) HN - 2022 BX - Hidden Bias BX - Implicit Bias BX - Subconscious Bias BX - Unconscious Bias MH - Biomolecular Condensates UI - D000091582 MN - A11.284.37 MS - Membraneless intracellular compartments formed through liquid-liquid phase separation from the surrounding CYTOPLASM or nucleoplasm or by the concentration of proteins and nucleic acids into droplets as they aggregate on static cellular structures such as CELL MEMBRANES. Examples include CELL NUCLEOLI; STRESS GRANULES; PARASPECKLES; HISTONE LOCUS BODIES; and POSTSYNAPTIC DENSITIES. HN - 2022 BX - Membraneless Organelles MH - Biosecurity UI - D000089062 MN - N4.452.910.150 MS - Institutional and personal security measures designed to prevent the loss, theft, misuse, diversion or intentional release of pathogens and toxins.(from https://www.who.int/influenza/pip/BiosecurityandBiosafety_EN_20Mar2018.pdf February,24, 2021) HN - 2022 BX - Bio-Security FX - Communicable Disease Control FX - Containment of Biohazards MH - Birth Cohort UI - D000089822 MN - M1.60.261 MS - Persons classified by a particular year or a specific time period of birth. HN - 2022 FX - Cohort Studies MH - Blood Flow Restriction Therapy UI - D000090003 MN - E2.760.169.63.500.387.125 MN - E2.779.483.125 MN - E2.831.535.483.125 MS - A technique which combines low intensity exercise with blood flow occlusion by use of a cuff. The cuff is placed close to the muscle being exercised thereby recreating a HYPOXIA to mimic the effects of high intensity exercise. HN - 2022 BX - BFR Therapy BX - Blood Flow Restriction Exercise BX - Blood Flow Restriction Training MH - BNT162 Vaccine UI - D000090982 MN - D12.776.828.868.228.500.750 MN - D20.215.894.865.450.500.750 MN - D20.215.894.899.85.500 MN - D23.50.865.450.500.750 MS - mRNA vaccine against SARS-CoV-2 developed by Pfizer and BioNTech. HN - 2022(2021) BX - COVID-19 Vaccine Pfizer-BioNTech MH - Body Odor UI - D000089083 MN - C23.888.104 MS - Strong or unusual odor related to the body. Occasional abnormal body odor may be a temporary effect of a metabolic change. HN - 2022 BX - Bromhidrosis MH - Brain-Gut Axis UI - D000087502 MN - G11.561.138 MS - An interactive network between the GASTROINTESTINAL TRACT (gut) and the brain principally mediated through the ENTERIC NERVOUS SYSTEM. Control of the gut activities during stress, for instance, is mediated by activation of neuroendocrine hormones (e.g., CORTICOTROPIN-RELEASING FACTOR). Conversely, INTESTINAL MICROBIOTA associate with the CENTRAL NERVOUS SYSTEM through the axis via microorganism-derived products (e.g., UROCORTINS). Some functional GASTROINTESTINAL DISORDERS (e.g., IRRITABLE BOWEL SYNDROME) have dysregulated brain-gut axis. HN - 2022 BX - Brain and Gut Axis BX - Brain-Gut-Microbiome Axis BX - Gut and Brain Axis BX - Gut-Brain Axis BX - Gut-Brain-Microbiome Axis BX - Microbiome-Brain-Gut Axis BX - Microbiome-Gut-Brain Axis BX - Microbiota-Brain-Gut Axis BX - Microbiota-Gut-Brain Axis FX - Gastrointestinal Microbiome MH - Brucea javanica UI - D000089003 MN - B1.875.800.575.912.250.898.111.500 MS - A plant species in the genus Brucea and the family SIMAROUBACEAE. It was formerly classified in the family ANACARDIACEAE. Its seeds have been used as traditional medicine and contain various QUASSINS including bruceines and brusatol. HN - 2022 BX - Brucea amarissima BX - Java Brucea BX - Rhus javanica MH - Candida auris UI - D000088063 MN - B1.300.107.795.95.363 MS - A species of yeast in genus Candida. C. auris infection is most often associated with immunocompromised patients in healthcare settings. INVASIVE CANDIDIASIS and colonization pose a treatment challenge when multidrug resistant strains are involved. AN - infection: coordinate with CANDIDIASIS or its indentions HN - 2022(2018) BX - C auri MH - Canonical Correlation Analysis UI - D000089342 MN - E5.318.740.150.500.250 MN - N5.715.360.750.125.500.250 MN - N6.850.520.830.150.500.250 MS - Mathematical procedure that transforms vectors of variables into canonical variate pairs and finds their correlation to describe strength of association. HN - 2022(2021) BX - Canonical Correlation BX - Canonical Variate MH - Cell Culture Techniques, Three Dimensional UI - D000087603 MN - E5.242.223.375 MS - Methods for growing cells in a way that they form three-dimensional shapes, such as on a three-dimensionally shaped substrate or as free-falling aggregates in stirred liquids. HN - 2022 BX - 3-D Cell Culture BX - 3-Dimensional Cell Culture BX - 3D Cell Culture MH - Cell Death Reversal UI - D000091442 MN - G4.146.477 MS - Recovery of cells from one of the activated pathways of regulated cell death. HN - 2022 BX - Anastasis BX - Apoptosis Reversal BX - Blebbishield Emergency Program BX - Ferroptosis Reversal BX - Necroptosis Reversal BX - Negative Regulation of Apoptosis BX - Reversal of Apoptosis MH - Cellular Automata UI - D000089682 MN - E5.599.32 MN - L1.224.50.531 MN - L1.224.160.187 MS - Space-oriented dynamic modeling ALGORITHMS acting in an array of cells, whose temporal states evolve based on the rules (algorithms) of the automata. They are used to model complex dynamic systems for study and analysis in a variety of scientific fields. HN - 2022 BX - Cellular Automata Model BX - Cellular Automation Model BX - Cellular Automaton MH - Census Tract UI - D000091368 MN - E5.318.740.933.249.500 MN - N6.850.520.830.933.249.500 MS - Small, relatively permanent statistical subdivisions of a county or equivalent entity that are updated by local participants prior to each decennial census as part of the U. S. Census Bureau's Participant Statistical Areas Program.(https://www.census.gov/programs-surveys/geography/about/glossary.html#par_textimage_13) HN - 2022 BX - Census Area BX - Census District MH - Centaurea benedicta UI - D000091322 MN - B1.875.800.575.912.250.100.188.500 MS - A plant species of the genus CENTAUREA and family ASTERACEAE. Members contain sesquiterpene lactone CNICIN. HN - 2022(2003) BX - Blessed Thistle BX - Cardo-Santo BX - Cnicus benedictus BX - Thistle, Blessed MH - Centenarians UI - D000087662 MN - M1.60.116.100.80.500 MS - Persons 100 years of age and older. HN - 2022(1987) MH - ChAdOx1 nCoV-19 UI - D000090985 MN - D20.215.894.865.450.250.500 MN - D20.215.894.899.85.63 MS - A viral vector vaccine against SARS-CoV-2 developed by AstraZeneca. Its vector encodes the SARS-CoV-2 Spike protein. HN - 2022(2021) BX - ChAdOx1 COVID-19 Vaccine BX - COVID-19 Vaccine AstraZeneca MH - Chemometrics UI - D000090022 MN - E5.196.168 MN - E5.318.740.244 MN - N6.850.505.300 MS - The use of statistical and mathematical methods to analyze chemical observations and phenomena, such as epidemiological analysis of spectroscopically identified bacteria or QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP. HN - 2022 BX - Chemometric Analysis BX - Chemometry MH - Child Poverty UI - D000091486 MN - I1.880.735.634.500 MS - A situation of children (ages 0-17 inclusive) living in households with income below the U.S. Depertment of Health and Human Services Federal Poverty Threshold, often leading to a lack of food, sanitation, shelter, health care and education needed to survive and thrive. HN - 2022 BX - Childhood Poverty MH - Chromobox Protein Homolog 5 UI - D000090266 MN - D12.776.660.235.300 MN - D12.776.664.235.300 MS - A protein located within beta-heterochromatin that is involved in suppression of POSITION EFFECT VARIEGATION. HN - 2022 (1991) BX - Heterochromatin Protein 1 BX - Heterochromatin-Specific Nonhistone Chromosomal Protein HP-1 BX - HP-1 Protein MH - Chronic Limb-Threatening Ischemia UI - D000089802 MN - C14.907.137.126.307.500.500 MN - C14.907.617.671.500 MN - C23.550.291.500.298 MN - C23.550.513.178 MS - A severe form of peripheral artery disease in which a hypoperfusion of the BLOOD through an organ or tissue is caused by occlusion of peripheral arterial vessels. It is associated with the presence of chronic ischemic rest pain, ulceration or GANGRENE. HN - 2022 BX - Critical Limb Ischemia MH - Citizenship UI - D000087482 MN - I1.880.604.473.326 MN - N3.706.437.326 MS - Status of a person recognized under the law of a sovereign nation as a member of or belonging to that nation. HN - 2022 BX - Naturalization MH - CLC-2 Chloride Channels UI - D000090007 MN - D12.776.157.530.400.175.94 MN - D12.776.543.550.450.175.94 MN - D12.776.543.585.400.175.94 MS - One of the nine mammalian members of the CHLORIDE CHANNEL family involved in chloride ion transport.It has several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. HN - 2022 (1995) BX - ClC-2 Channel BX - ClC-2 Chloride Channel MH - Climate Models UI - D000090082 MN - E5.599.520 MN - I1.320.250 MS - Computer representations that simulate or predict the behavior or activity of WEATHER systems, processes, or phenomena. HN - 2022 BX - Climate Simulation MH - Cognitive Psychology UI - D000090182 MN - F4.96.628.17 MN - F4.96.628.255.750 MS - Branch of psychology that explores the operation of mental processes related to perceiving, attending, thinking, language, and memory, mainly through inferences from behavior. (APA Dictionary of Psychology. https://dictionary.apa.org/cognitive-psychology, accessed 3/22/2021). HN - 2022 MH - Cognitive Restructuring UI - D000088686 MN - F4.754.137.350.375 MS - A technique drawn from COGNITIVE BEHAVIOR THERAPY that helps an individual to identify, challenge and alter stress-inducing thought patterns and beliefs. HN - 2022 BX - Cognitive Reframing MH - Collagen Type I, alpha 1 Chain UI - D000090602 MN - D5.750.78.280.300.100.500 MS - A fibrillar collagen found predominantly in BONE and SKIN. HN - 2022 (2000) BX - COL1A1 Protein BX - Collagen alpha 1 (I) BX - Collagen Type I, alpha 1 Subunit BX - Pro alpha 1 Collagen BX - Pro-alpha1(I) Collagen BX - Procollagen alpha1(I) BX - Type I Collagen alpha 1 MH - Community Resources UI - D000091444 MN - I1.880.853.75 MN - N3.55 MS - The financial, material, and/or human assets of a community which have the potential to improve the QUALITY OF LIFE in community. HN - 2022 MH - Community Support UI - D000091443 MN - I1.880.853.500.600.250 MN - N2.421.143.212.150 MS - Community support systems that may be organized through extended family members, friends, neighbors, religious organizations, community programs, cultural and ethnic organizations, or other support groups or organizations. (https://www.lawinsider.com/dictionary/community-support-systems) HN - 2022 MH - Computerized Adaptive Testing UI - D000090242 MN - I2.594.500 MS - Testing administered with level of difficulty l is tailored to the test taker. HN - 2022 MH - Constitutive Androstane Receptor UI - D000090702 MN - D12.776.826.60 MS - A member of the nuclear receptor superfamily (subfamily 1, group I, member 3 [NR1i3]) involved, along with PREGNANE X RECEPTOR, in regulation of cellular responses to the exogenous and endogenous chemicals such as detoxification of XENOBIOTICS. HN - 2022 (2000) BX - CAR Nuclear Receptor BX - CAR Orphan Nuclear Receptor BX - Constitutive Active Receptor BX - Constitutive Androstane Receptor beta MH - Coptis chinensis UI - D000089042 MN - B1.875.800.575.912.250.836.750.229.500 MS - A plant species of the genus COPTIS and family RANUNCULACEAE. Dried rhizome (huang-lian) has been used in TRADITIONAL CHINESE MEDICINE. It contains isoquinoline ALKALOIDS (e.g., BERBERINE and coptisine). HN - 2022 BX - Chinese Goldthread BX - Huang-Lian MH - Coral Bleaching UI - D000088982 MN - G16.500.188 MS - The process whereby large extents of CORAL rapidly pale through loss of their algal endosymbionts via destabilization of the coral–algal SYMBIOSIS. (from https://doi.org/10.1111/mec.15337, January 11, 2021) HN - 2022 FX - Coral Reefs MH - Core Stability UI - D000089944 MN - F2.830.816.541.752.500 MN - G7.888.750.500.500 MN - G11.427.690.500 MN - G11.561.790.541.595.500 MS - A POSTURE in which an ideal body mass distribution is achieved for the ABDOMINAL CORE. Abdominal core stability and balance provides the body an ability to maintain equilibrium and control of the SPINE and PELVIC REGION during movement. HN - 2022 BX - Core Balance MH - Corticobasal Degeneration UI - D000088282 MN - C10.574.945.312 MS - Rare progressive neurological disorder characterized by Parkinsonism, cortical atrophy of multiple areas of the brain including the cerebral cortex and the basal ganglia, cognitive dysfunction and eye movement abnormalities. HN - 2022 BX - Cortico-basal Degeneration BX - Cortico-basal Ganglionic Degeneration BX - Corticobasal Syndrome MH - Cyanobacteria Toxins UI - D000087522 MN - D23.946.123.257 MS - Toxic secondary metabolites produced CYANOBACTERIA. HN - 2022 BX - Cyanobacterial Neurotoxin BX - Cyanobacterial Neurotoxins BX - Cyanobacterial Toxins BX - Cyanotoxins FX - Toxoids MH - Cytochrome P-450 CYP2J2 UI - D000090762 MN - D8.244.453.03 MN - D8.811.682.690.708.170.05 MN - D10.251.355.128 MN - D12.776.422.220.453.05 MS - A cytochrome P450 enzyme involved in oxidizing POLYUNSATURATED FATTY ACIDS (PUFA) to PUFA epoxides which function as potent lipid mediators. This enzyme, encoded by CYP2J2 gene, metabolizes ARACHIDONIC ACID to epoxyeicosatrienoic acids (EETs) which produce biological effects including VASODILATION. HN - 2022 (1985) BX - Arachidonate Epoxygenase BX - Arachidonic Acid Epoxygenase BX - Cytochrome P-450 Arachidonate Oxygenase BX - Cytochrome P-450 Epoxygenase BX - NADPH-Dependent Arachidonic Acid Epoxygenase MH - Cytoplasmic Ribonucleoprotein Granules UI - D000088123 MN - A11.284.430.214.190.500.780 MN - A11.284.430.214.190.875.190.190.384 MS - Non-membranous subcompartments containing RIBONUCLEOPROTEIN complexes. They are found in the CYTOPLASM and often share multiple protein and/or RNA components. Membraneless RNP subcompartments found in the nucleus are referred to as nuclear bodies (e.g., PARASPECKLES). HN - 2022 BX - Cytoplasmic RNA Granules BX - Cytoplasmic RNP Granule BX - Cytoplasmic RNP Granules BX - Neuronal Granules BX - Neuronal Ribonucleoprotein Granules BX - Ribonucleoprotein Granules BX - RNA Granules MH - Dacryocystography UI - D000090104 MN - E1.370.350.240 MS - An image guided examination of the NASOLACRIMAL APPARATUS including NASOLACRIMAL DUCT. HN - 2022 MH - Decellularized Extracellular Matrix UI - D000091083 MN - A11.284.295.310.140 MN - D25.130.535 MN - D27.720.102.130.500 MN - J1.637.51.130.535 MS - A biomaterial with a network of macromolecules with varying composition and organization of tissue-specific proteins and polysaccharides. It is prepared from organs and tissues by decellularization (e.g., with a detergent) to mimic native microenvironment for tissue-specific functions. HN - 2022 BX - Decellularized ECM MH - Deep Eutectic Solvents UI - D000091463 MN - D27.720.844.250 MS - A fluid that is generally composed of two or three safe (cheap, non-toxic, renewable, and biodegradable) components that are capable of self-association, often through hydrogen bond interactions, to form a liquid close to the eutectic composition, i.e., the molar ratio of the components which has the lowest melting point (eutectic point). HN - 2022 BX - Deep Eutectic Mixtures BX - Natural Deep Eutectic Solvents FX - Green Chemistry Technology MH - Defective Interfering Viruses UI - D000089783 MN - B4.265.135 MS - Naturally occurring or synthetically made defective mutant viral genomes and particles which are incompetent in independent replication and interfere with normal VIRUS REPLICATION. Some synthetic defective interfering genomes may stimulate INNATE IMMUNE RESPONSE and are candidates for potential vaccine and therapeutic approaches for virus infections. HN - 2022(1988) BX - Defective Interfering Genome BX - Defective Interfering Particles BX - Natural Defective Interfering Viruses BX - Synthetic Defective Interfering Genome Viruses BX - Synthetic Defective Interfering Particles BX - Synthetic Defective Interfering Virus BX - Synthetic Defective Interfering Viruses MH - Delta-5 Fatty Acid Desaturase UI - D000090943 MN - D8.811.682.690.708.392.390 MS - A fatty acid desaturase that is a rate-limiting enzyme for the conversion from dihomo-gamma-linolenic acid and EICOSATETRAENOATE (ETA) in the synthesis of ARACHIDONIC ACID and EICOSAPENTAENOATE (EPA). It is also involved in the biosynthesis of unsaturated fatty acids from the polyunsaturated fatty acids (PUFA), LINOLEIC ACID (LA), and ALPHA LINOLENIC ACID (ALA) precursors and plays an important role in the metabolism of inflammatory lipids including PROSTAGLANDIN E2. HN - 2022 (1981) BX - Delta 5 Desaturase BX - Delta-5-FADase BX - Fatty Acid Delta-5-Desaturase MH - Dense Core Vesicles UI - D000088482 MN - A11.284.430.214.190.875.190.880.810.250 MS - Membrane-bound electron-dense organelles, 50–200 nm in size found in neurons and endocrine cells. Dense core vesicles package cargo molecules (NEUROPEPTIDES; NEUROTRANSMITTERS and MiRNAs) in a granular internal matrix. Neuronal dense core vesicles release their cargo content by EXOCYTOSIS. HN - 2022(2001) BX - Dense Core Granules BX - Dense-Core Granules BX - Dense-Core Vesicles BX - Large Dense Core Granules BX - Large Dense Core Vesicles BX - Large Dense-Core Granules BX - Large Dense-Core Vesicles BX - LDCVs BX - SDCGs BX - Small Dense Core Granules BX - Small Dense Core Vesicles BX - Small Dense-Core Granules BX - Small Dense-Core Vesicles MH - Designed Ankyrin Repeat Proteins UI - D000090922 MN - D12.776.828.150 MN - J1.637.87.375 MS - Genetically engineered antibody MIMETIC PROTEINS, derived from ANKYRIN PROTEINS. They offer advantages over antibodies because of their highly specific target PROTEIN BINDING with high affinity and specificity. HN - 2022 BX - DARPin BX - DARPins MH - Diaschisis UI - D000087505 MN - C10.228.140.390 MS - Loss or decreased brain function within intact region of the brain distant from the site of the lesion. HN - 2022 BX - Connectional Diaschisis BX - Focal Diaschisis MH - Digit Ratios UI - D000090402 MN - E1.370.600.24.350 MN - E5.41.124.473 MN - N6.850.505.200.100.550 MS - Ratio between lengths of fingers and/or toes that is sometimes characteristic of an exposure to ENDOCRINE DISRUPTORS during FETAL DEVELOPMENT. HN - 2022 BX - Digit Length Ratio BX - Digit Ratio BX - Finger Length Ratio MH - Dihydroorotate Dehydrogenase UI - D000090722 MN - D8.811.682.660.313 MS - An oxidoreductase that catalyzes the conversion of DIHYDROOROTATE to orotate with QUINONE as an electron acceptor in the biosynthesis of PYRIMIDINES. HN - 2022 (1990) BX - DHODH BX - DHOO-Dehydrogenase-U BX - Dihydro-Orotate Dehydrogenase BX - Dihydro-Orotate-Cytochrome C Reductase BX - Dihydroorotate Dehydrogenase (Ubiquinone) BX - Dihydroorotate Dehydrogenase Type A BX - Dihydroorotate Dehydrogenase Type B BX - Dihydroorotate Dehydrogenase Type C BX - Dihydroorotate-Ubiquinone Oxidoreductase MH - Disability-Adjusted Life Years UI - D000087509 MN - E5.318.308.985.450.250 MN - N1.224.935.464.250 MN - N6.850.505.400.975.450.250 MN - N6.850.520.308.985.450.250 MS - It is the sum of years of life lost due to PREMATURE MORTALITY and the number of years lived with disability, due to disease or health condition in a population. This is a measurement of BURDEN OF DISEASE. HN - 2022 BX - DALYs BX - Years Lived With Disability MH - Disinformation UI - D000087862 MN - F1.145.813.157.500 MN - L1.143.790.500 MS - False information deliberately and often covertly spread in order to influence public opinion or obscure the truth. (https://www.merriam-webster.com/dictionary/disinformation) HN - 2022 BX - Fake News MH - Dissolved Organic Matter UI - D000090422 MN - D2.332 MN - D20.313 MS - A heterogeneous class of water-soluble compounds containing covalently bound CARBON that are derived from a variety of biological and geological sources during the biogeochemical cycling of carbon (CARBON CYCLE). HN - 2022 BX - Dissolved Organic Carbon BX - Dissolved Organic Chemicals BX - Dissolved Organic Compounds BX - Dissolved Organic Nitrogen BX - Dissolved Organic Phosphorus MH - DNA Methyltransferase 3A UI - D000090205 MN - D8.811.913.555.500.350.100.500.750 MS - A methyltransferase that catalyzes the addition of a methyl group to CYTOSINE residues of CpG dinucleotides and is required for genome-wide de novo DNA METHYLATION. HN - 2022 (1999) BX - DNA Methyltransferase 3 alpha BX - DNMT3A Protein MH - Dorsolateral Prefrontal Cortex UI - D000087643 MN - A8.186.211.200.885.287.500.270.700.750 MS - The upper surfaces of the prefrontal cortex comprising the rostral parts of the superior frontal gyrus and the middle frontal gyrus. It is involved in EXECUTIVE FUNCTION. HN - 2022(2016) BX - Brodmann Area 46 BX - Brodmann Area 9 BX - Brodmann Area 9 and 46 BX - Brodmann Areas 9 and 46 BX - Brodmann's Area 46 BX - Brodmann's Area 9 BX - Brodmann's Area 9 and 46 BX - Brodmann's Areas 9 and 46 BX - DLPFC MH - Doublecortin Domain Proteins UI - D000089622 MN - D12.776.220.600.450.125 MS - A family of microtubule-associated proteins that share in common a tandem repeat of evolutionarily conserved protein domains initially found in DOUBLECORTIN PROTEIN. HN - 2022(1998) BX - Doublecortin-like Proteins BX - Doublecortins MH - Doublecortin Protein UI - D000089662 MN - D12.776.220.600.450.125.500 MN - D12.776.631.560.113 MS - A microtubule-associated protein that is primarily found in neuronal precursor cells and immature NEURONS in embryonic and adult cortical structures. HN - 2022(1998) BX - Lissencephaly, X-Linked Protein FX - Classical Lissencephalies and Subcortical Band Heterotopias MH - Doublecortin-Like Kinases UI - D000089742 MN - D8.811.913.696.620.682.700.275 MN - D12.776.220.600.450.125.750 MN - D12.776.476.563.275 MS - A family of doublecortin domain-containing serine-threonine kinases that were originally identified in neuronal cells. HN - 2022 BX - Doublecortin-Like Kinase 1 BX - Doublecortin-Like Kinase 2 BX - Doublecortin-Like Kinase Proteins MH - Economic Stability UI - D000091002 MN - I1.880.853.996.134.500 MS - An absence of excessive economic fluctuations which allows people the ability to access resources. (https://www.ruralhealthinfo.org/toolkits/sdoh/2/economic-stability/index#:~:text=Economic%20stability%20allows%20people%20the,provides%20a%20stable%2C%20living%20wage.&text=Income%2Fpoverty%20and%20financial%20resources) HN - 2022 BX - Economic Instability MH - Elite Controllers UI - D000088064 MN - M1.860.375 MS - Infected individuals with naturally low levels of pathogen replication (e.g., HIV LONG-TERM SURVIVORS with low VIRAL LOAD of HIV) and remain healthy. Some elite controllers have immune systems which prevent disease progression (e.g., high CD4 COUNTS). Studies of how they remain disease-free may contribute to development of new therapeutic approaches and targets. HN - 2022 BX - Elite Suppressors BX - Long-Term Non-Progressors BX - Long-Term Nonprogressors BX - Viremic Controllers FX - Asymptomatic Diseases MH - Endoplasmic Reticulum Chaperone BiP UI - D000091342 MN - D12.776.580.216.375.100 MS - An ENDOPLASMIC RETICULUM specific chaperone of the HSP70 family. They are involved in folding and oligomerization of secreted and membrane proteins and ENDOPLASMIC RETICULUM STRESS related UNFOLDED PROTEIN RESPONSE. HN - 2022(2008) BX - Binding-immunoglobulin Protein Molecular Chaperone BX - Glucose Regulated Protein 78 kDa BX - Grp78 BX - Heat-Shock Protein 5 BX - HSPA5 Protein BX - Molecular Chaperone BiP BX - Molecular Chaperone GRP78 MH - Endotoxin Tolerance UI - D000087523 MN - G12.535.425.290 MS - Reduced capacity to respond to subsequent ENDOTOXIN challenges after an initial exposure. It is characterized by reduced responsiveness of INNATE IMMUNE RESPONSES, a shift from pro- to anti-inflammatory cell phenotype and impaired ANITGEN PRESENTATION. HN - 2022 BX - Endotoxin Desensitization MH - Environmental Justice UI - D000091383 MN - I1.738.458.500 MN - I1.880.604.473.700.500 MN - K1.752.566.479.830.750.500 MN - K1.752.566.869.250 MS - The fair treatment and meaningful involvement of all people regardless of race, color, national origin, or income, with respect to the development, implementation, and enforcement of environmental laws, regulations, and policies. (https://www.epa.gov/environmentaljustice/learn-about-environmental-justice) HN - 2022 MH - Environmentalism UI - D000088724 MN - I1.738.458 MN - N6.230.206 MS - Advocacy for the preservation, restoration, or improvement of the natural environment. It aims to reduce the impact of human activities on the earth and its inhabitants. HN - 2022 BX - Environmental Activism BX - Environmental Advocacy MH - Epidemiological Models UI - D000090005 MN - E5.599.395.121 MS - Mathematical models of the transmission of infectious diseases. They predict spread of a disease by incorporating disease-related (e.g., infectious agent, mode of transmission, latent period, infectious period) and abiotic factors (e.g., social, cultural, demographic, and geographic factors). HN - 2022 BX - Communicable Disease Models BX - Compartmental Models BX - Models, Epidemiological BX - SIR Models BX - SIS Model BX - Susceptible Infected Recovered Models BX - Susceptible Infected Susceptible Model MH - Erythema Ab Igne UI - D000089965 MN - C17.800.229.100 MN - C23.888.885.328.500 MN - C26.200.413 MS - A cutaneous finding caused by prolonged heat exposure (e.g., space heater) and local heat injury (e.g., caused by LASER THERAPY). It is characterized by epidermal atrophy, reticular hyperpigmentation, and telangiectatic dermatosis. HN - 2022 MH - Escitalopram UI - D000089983 MN - D2.92.831.230 MN - D2.626.295 MN - D3.633.100.127.203 MS - S-enantiomer of CITALOPRAM. Belongs to a class of drugs known as SELECTIVE SEROTONIN REUPTAKE INHIBITORS, used to treat depression and generalized anxiety disorder. HN - 2022 (2001) MH - Ethnic and Racial Minorities UI - D000091762 MN - I1.880.853.125 MS - Socially constructed groups of people who differ in race, color or national, religious, or cultural origin from the dominant group and is often the majority population of the country in which they live. Ethnic minority groups generally share a common sense of identity and common characteristics such as language, religion, tribe, nationality, race, or a combination thereof. AN - coordinate with specific ethnic group or racial group if pertinent HN - 2022 BX - Ethnic Minorities BX - Racial Minorities MH - European Alpine Region UI - D000090142 MN - Z1.542.25 MS - A territory which encompasses eight European countries: Austria, France, Germany, Italy, Liechtenstein, Monaco, Slovenia and Switzerland. The height of the Alpine mountain ridges range up to Mont Blanc at 15,782 feet above sea level, and its altitude decreases from west to east. AN - do not confuse with ALPINE TUNDRA see TUNDRA HN - 2022 BX - Alpine Region BX - Alps Mountain Region MH - Ex utero Intrapartum Treatment Procedures UI - D000088103 MN - E2.467.625 MN - E4.520.252.500.575 MS - Prenatal interventions to manage fetal anomalies or FETAL DISEASES ex utero while maintaining the uteroplacental circulation during obstetric delivery. EXIT procedures are divided into EXIT-to-airway; EXIT-to-ECMO; and EXIT-to-resection. HN - 2022 BX - Ex utero Intrapartum Technique Procedures BX - Ex-utero Intrapartum Technique Procedures BX - Ex-utero Intrapartum Treatment Procedures BX - EXIT Procedures BX - EXIT-to-Airway BX - EXIT-to-Airway Procedure BX - EXIT-to-ECMO Procedure BX - EXIT-to-Extra-Corporeal Membrane Oxygenation BX - EXIT-to-Extra-Corporeal Membrane Oxygenation Procedure BX - EXIT-to-Resection BX - EXIT-to-Resection Procedure MH - Exergaming UI - D000088544 MN - G11.427.410.698.277.140 MN - I3.350.140 MN - I3.450.642.693.930.500 MN - L1.224.900.930.500 MS - Videogaming that involves the player's whole body in physical exercises in order to play the videogames. HN - 2022 BX - Active-Video Gaming BX - Exergames BX - Virtual Reality Exercise FX - Telerehabilitation MH - Fermented Beverages UI - D000088082 MN - G7.203.100.559 MN - G7.203.200.563 MN - J2.200.559 MN - J2.350.594 MS - Beverages that are prepared by using microorganisms to convert their components into various FERMENTATION end products. HN - 2022; use FERMENTED FOODS AND BEVERAGES 2020-2021 BX - Cauim BX - Chicha BX - Fermented Beverage BX - Masato BX - Pulque MH - Fibroblast Growth Factor-23 UI - D000089703 MN - D12.644.276.624.600 MS - A specific fibrobroblast growth factor that is primarily synthesized by OSTEOCYTES and OSTEOBLASTS. It is involved in regulating phosphate homeostasis and renal phosphate excretion. HN - 2022 BX - Fibroblast Growth Factor 23 MH - Filaggrin Proteins UI - D000091344 MN - D12.776.157.125.750.250 MN - D12.776.631.655.250 MS - S100 proteins that aggregate KERATINS. Filaggrin precursor proteins are localized in keratohyalin granules and processed into individual functional filaggrin molecules during terminal epidermis differentiation. Mutations in fillagrins are associated with ICHTHYOSIS VULGARIS. HN - 2022(1981) BX - Filaggrin BX - Filaggrin Protein BX - Profilaggrin BX - Stratum Corneum Basic Protein BX - Stratum Corneum Basic Protein Precursor MH - Focal Facial Dermal Dysplasias UI - D000090303 MN - C16.131.77.350.568 MN - C16.131.831.350.568 MN - C16.320.850.250.568 MN - C17.800.804.350.568 MN - C17.800.827.250.568 MS - A heterogenous group of genetic disorders characterized by scar-like atrophic lesions on the temple region of the head including preauricular area. Location of skin defects is likely related to defects in fusion of embryonic facial prominences during development of the face. Focal facial dermal dysplasia (FFDD) is generally divided into four subtypes according to the location of the lesions and inheritance pattern: FFDD1 (Brauer syndrome); FFDD2 (Brauer-Setleis syndrome); FFDD3 (Setleis syndrome); and FFDD4. Mutations in TWIST2 Protein and/or CYP26C1 (see CYP26 FAMILY) are associated with FFDD3, and 4. HN - 2022 BX - Bitemporal Aplasia Cutis Congenita BX - Bitemporal Forceps Marks Syndrome BX - Brauer Syndrome BX - Brauer-Setleis Syndrome BX - Facial Ectodermal Dysplasias BX - FFDD, Type 1 BX - FFDD, Type 2 BX - FFDD, Type 3 BX - FFDD, Type 4 BX - Focal Facial Dermal Dysplasia 1 BX - Focal Facial Dermal Dysplasia 2 BX - Focal Facial Dermal Dysplasia 3 BX - Focal Facial Dermal Dysplasia 4 BX - Focal Facial Dermal Dysplasia Type 1 BX - Focal Facial Dermal Dysplasia Type 2 BX - Focal Facial Dermal Dysplasia Type 4 BX - Hereditary Symmetrical Aplastic Nevi of Temples BX - Setleis Syndrome MH - Fractional Exhaled Nitric Oxide Testing UI - D000089142 MN - E1.370.100.500 MS - Test to measure the levels of NITRIC OXIDE (an ENDOTHELIUM-DEPENDENT RELAXING FACTOR) in the exhaled air. FeNO test is used to determine levels of inflammation in the pulmonary ENDOTHELIUM often associated with endothelium associated diseases, e.g., ASTHMA. HN - 2022 BX - Exhaled Nitric Oxide Test BX - FeNO Test BX - Fractional Exhaled Nitric Oxide FX - Nitric Oxide MH - Gamification UI - D000090208 MN - I2.487 MN - L1.224.900.340 MS - Application of game mechanics to non-game contexts to engage audiences and to inject some entertainment into mundane activities besides generating motivational and cognitive benefits. HN - 2022 MH - Gamma Secretase Inhibitors and Modulators UI - D000091062 MN - D27.505.519.389.315 MS - Agents that suppress GAMMA-SECRETASE by inhibiting or modulating its activities. Targeted enzymatic activities include its involvement in accumulation of toxic AMYLOID BETA-PEPTIDES (e.g., Aβ42) in ALZHEIMER DISEASE and activation of NOTCH RECEPTOR mediated SIGNAL PATHWAYS in certain cancer types. HN - 2022 BX - Gamma Secretase Inhibitors BX - Gamma Secretase Modulators BX - GS Inhibitors BX - GS Inhibitors and Modulators BX - GS Modulators MH - Gaslighting UI - D000090206 MN - L1.143.790.750 MS - Form of emotional or psychological abuse where an individual (or a group) makes someone question their perceptions of reality—including their memories, their thoughts, and the events taking place around them. It often exploits “gender-based stereotypes and structural and institutional inequalities.. HN - 2022 BX - Medical Gaslighting MH - Genital Diseases UI - D000091662 MN - C12.100 MS - Pathological processes involving the reproductive tract (GENITALIA). AN - general or unspecified; GENITAL DISEASES, MALE and GENITAL DISEASES, FEMALE are available HN - 2022 MH - Genitourinary Agents UI - D000089162 MN - D27.505.954.493 MS - Drugs used in treatment of medical conditions found in REPRODUCTIVE ORGANS and the URINARY TRACT such as URINARY INCONTINENCE; ERECTILE DYSFUNCTION; and PRETERM LABOR prevention. HN - 2022 BX - Genitourinary Tract Agents BX - Impotence Agents MH - Genomic Medicine UI - D000088744 MN - E2.479 MN - H2.403.200.550 MS - A medical discipline using genomic information about an individual as part of their clinical care (e.g. for diagnostic or therapeutic decision-making) and the health outcomes and policy implications of that clinical use. (From www.genome.gov/health/Genomics-and-Medicine accessed 12/28/2020) HN - 2022 MH - Germ Cell Ribonucleoprotein Granules UI - D000088262 MN - A11.284.430.214.190.500.780.250 MN - A11.284.430.214.190.875.190.190.384.250 MS - Cytoplasmic structures organized by RIBONUCLEOPROTEINS involved in RNA regulation in GERM CELLS. HN - 2022 BX - Chromatoid Bodies BX - Germ Cell RNP Granules BX - Germ Granules BX - Germline P Granules BX - Germline P-Granules BX - Germline Z Granules BX - Germline Z-Granules BX - P Granules BX - P-Granules BX - Primordial Germ Cell Granules BX - Sponge Bodies BX - Z Granules BX - Z-Granules MH - Geroscience UI - D000089323 MN - H1.158.595 MN - H2.403.355.500 MS - The study of the BIOLOGY; BIOCHEMISTRY; and PHYSIOLOGY of AGING and the AGED and age-related diseases such as CARDIOVASCULAR DISEASES; DIABETES MELLITUS; and CANCER, as well as debilitating conditions like ARTHRITIS; FATIGUE; and FRAILTY. HN - 2022 BX - Aging Research BX - Anti-Aging Research MH - Haptic Interfaces UI - D000089922 MN - L1.224.230.260.115.625 MS - Computer peripherals that enable users to interact three dimensionally with objects in virtual environments, or with equipment being teleoperated, by receiving kinesthetic, tactile, and force feedback. HN - 2022 BX - Force Feedback Gloves BX - Haptic Actuators BX - Haptic Computer Interfaces BX - Haptic Devices BX - Haptic Glove MH - Haptic Technology UI - D000089862 MN - J1.293.69.375 MN - J1.897.380 MN - J1.897.441.500 MN - L1.224.160.875.500 MN - L1.296.555.500 MS - The study of the use of touch and KINESTHESIS in order to produce HAPTIC COMPUTER INTERFACES that will allow users to interact with digital objects by kinesthetic feedback, force feedback, and tactile feedback. HN - 2022 BX - Haptic Communication Technology BX - Haptic Feedback Technology BX - Haptic Perception Technology BX - Haptics BX - Touch Feedback Technology FX - Haptic Interfaces FX - Nonverbal Communication MH - HCV NS3-4A Protease Inhibitors UI - D000088802 MN - D27.505.519.389.745.900.375 MS - A direct acting antiviral compound that inhibits hcv ns3-4a protease. It is used to treat chronic HEPATITIS C VIRUS. HN - 2022 BX - NS3 4A Protease Inhibitors MH - Health Disparity, Minority and Vulnerable Populations UI - D000091202 MN - M1.270 MS - Groups of persons whose special characteristics make them a minority, vulnerable, and frequently subjected to conditions with limited levels of access to health care and other opportunities. AN - INDEXER: Do not use; CATALOGER: Do not use HN - 2022 MH - Health Inequities UI - D000091682 MN - I1.240.425.513 MN - N1.224.425.394 MS - Differences in health status or in the distribution of health resources between different population groups, arising from the social conditions in which people are born, grow, live, work and age.(https://www.who.int/news-room/facts-in-pictures/detail/health-inequities-and-their-causes#:~:text=Health%20inequities%20are%20differences%20in,right%20mix%20of%20government%20policies.) HN - 2022 MH - Healthy Life Expectancy UI - D000087508 MN - E5.318.308.985.450.500 MN - N1.224.935.464.500 MN - N6.850.505.400.975.450.500 MN - N6.850.520.308.985.450.500 MS - The expected number of remaining years of life spent in good health from a particular age, assuming current rates of mortality and morbidity. HN - 2022 BX - Disability-Free Life Expectancy BX - HALYs BX - Health-Adjusted Life Years MH - Hippo Signaling Pathway UI - D000090683 MN - G2.111.820.200 MN - G4.835.300 MS - A signaling pathway that plays a key role in regulating tissue and organ growth. The name derives from the protein kinase Hippo (Hpo) found in DROSOPHILA; where mutations of the Hpo gene result in tissue overgrowth and the hippopotamus phenotype. HN - 2022 BX - Hippo Pathway BX - Hippo Signaling MH - HIV Non-Progressors UI - D000088302 MN - M1.860.375.500 MN - M1.860.400.500 MS - HIV-positive individuals with low VIRAL LOAD of HIV who never develop AIDS even without antiviral treatment. HN - 2022(1999) BX - HIV Controllers BX - HIV Elite Controllers BX - HIV Infected Long-Term Non-Progressors BX - HIV Infected Viremic Controllers BX - HIV Long-Term Nonprogressors BX - HIV Viremic Controllers BX - HIV+ Long-Term Non-Progressors BX - HIV-1 Infected Viremic Controllers BX - HIV-1 Long-Term Nonprogressors MH - Home Environment UI - D000091502 MN - I1.880.853.450.641 MN - I1.880.853.500.450 MN - N1.224.791.300 MN - N1.824.308.250 MN - N6.230.278 MN - N6.850.505.400.800.300 MS - Aspects of peoples’ living conditions that may and can impact people's health and/or well-being. These factors may be physical (e.g., housing quality) or social circumstances (e.g., living alone). HN - 2022 BX - Living Alone BX - Social Housing Conditions FX - Built Environment MH - Homeobox Protein Nkx-2.2 UI - D000090322 MN - D12.776.260.400.230 MN - D12.776.660.415 MN - D12.776.930.321 MS - A homeobox-containing transcription factor that functions in INSULIN-SECRETING CELLS. Mutations in the NKX2-2 gene are associated with MATURITY-ONSET DIABETES OF THE YOUNG and OLIGODENDROGLIOMA. HN - 2022 (1995) BX - Nkx-2.2 Homedomain Protein BX - Nkx-2.2 Protein BX - Nkx2.2 Protein MH - Homozygous Familial Hypercholesterolemia UI - D000090542 MN - C16.320.565.398.481.500 MN - C18.452.584.500.500.644.475.500 MN - C18.452.584.563.481.500 MN - C18.452.648.398.481.500 MS - A rare inherited genetic disorder, one form of HYPERLIPOPROTEINEMIA TYPE II, characterized by high level of LOW-DENSITY LIPOPROTEIN (LDL) which if not treated could elevate the chance of heart attack at an early age. HN - 2022 BX - Autosomal Recessive Hypercholesterolemia BX - HoFH FX - Receptors, LDL MH - Hospital to Home Transition UI - D000088745 MN - E2.760.169.94 MN - N2.421.585.169.94 MS - Patient-centered hospital discharge to home planning and transition. HN - 2022 BX - Hospital to Home MH - Housing Instability UI - D000091003 MN - I1.880.853.996.134.750 MN - N1.824.363 MS - This encompasses a number of challenges, such as having trouble paying rent, living in overcrowded conditions, moving frequently, living with friends or relatives out of necessity, being unhoused, or spending the bulk of household income (>50%) on housing. (https://www.healthypeople.gov/2020/topics-objectives/topic/social-determinants-health/interventions-resources/housing-instability) HN - 2022 BX - Housing Insecurity MH - Housing Quality UI - D000091522 MN - I1.880.853.450.641.500 MN - I1.880.853.500.450.500 MN - N1.224.791.300.500 MN - N6.230.145.500.500 MS - Physical condition of a person’s home as well as the quality of the social and physical environment in which the home is located. Aspects of housing quality include air quality, home safety, space per individual, and the presence of mold, asbestos, or lead. Housing quality is affected by factors like a home’s design and age.(https://www.healthypeople.gov/2020/topics-objectives/topic/social-determinants-health/interventions-resources/quality-of-housing) HN - 2022 BX - Housing Conditions MH - Hunting UI - D000090262 MN - I3.400 MN - I3.450.642.637 MS - Finding or capuring animals for food or sport. AN - human activity only; check tag humans HN - 2022 BX - Fishing BX - Trapping MH - Immunological Memory Cells UI - D000091244 MN - A11.118.637.555.567.269 MS - Antigen-specific immunologic cells which have a potential to form IMMUNOLOGIC MEMORY providing a rapid and robust response against a second encounter with the same antigen. Immunologic memory cells typically include B-Lymphocytes T-Lymphocytes and sometimes adaptive NK cells. Building immunologic memory cells is a basis of how a vaccine affords immunity to a specific pathogen. HN - 2022 BX - Immunologic Memory Cells BX - Memory Cells, Immunologic BX - Memory Cells, Immunological MH - Immunomodulating Agents UI - D000091369 MN - D27.505.696.477.396 MS - Agents that alter the response of the immune system by activating (IMMUNOSTIMULANT) or suppressing (IMMUNOSUPPRESSIVE) the immune system and may help the body fight cancer, infection, or other diseases. HN - 2022 BX - IMiDs BX - Immunomodulating Drugs BX - Immunomodulatory Agents BX - Immunomodulatory Compounds BX - Immunomodulatory Drugs BX - Immunomodulatory IMiD Drugs BX - Immunomodulatory IMiDE Drugs MH - Infodemic UI - D000089102 MN - L1.143.443.500 MS - Typically refers to a rapid and far-reaching spread of both accurate and inaccurate information about something, such as a disease. As facts, rumors, and fears mix and disperse, it becomes difficult to learn essential information about an issue. (from Merriam Webster Dictionary) HN - 2022 MH - Infodemiology UI - D000090462 MN - L1.313.750.500 MS - The study of determinants and distribution of health information and misinformation in electronic media to inform public heath and public policy in the prevention, detection, and management of INFODEMICS. HN - 2022 BX - Infoveillance MH - Information Avoidance UI - D000087366 MN - F1.393.537 MS - Choosing to not obtain knowledge even if having the information could be to one's benefit. HN - 2022 BX - Information Denial FX - Avoidance Learning MH - Insular Cortex UI - D000087623 MN - A8.186.211.200.885.287.500.364 MS - A pyramidal shaped region of cerebral cortex located deep below the lateral fissure in PRIMATES. It is surrounded by the SUPERIOR TEMPORAL GYRUS, the rostral PARIETAL LOBE, the INFERIOR FRONTAL GYRUS and the ORBITAL GYRI. It is the primary gustatory cortex and is involved in sensorimotor and somatosensory as well as socioemotional functions. HN - 2022(1979) BX - Brodmann Area 13 BX - Brodmann Area 14 BX - Brodmann Area 15 BX - Brodmann Area 16 BX - Brodmann Area 43 BX - Brodmann's Area 13 BX - Brodmann's Area 14 BX - Brodmann's Area 15 BX - Brodmann's Area 16 BX - Brodmann's Area 43 BX - Central Lobe BX - Gustatory Cortex BX - Insula of Reil BX - Insular Gyrus BX - Insular Region BX - Lobus Insularis BX - Opercular Cortex BX - Primary Gustatory Cortex BX - Visceral Cortex MH - Interleukin Inhibitors UI - D000088902 MN - D27.505.696.477.656.563 MS - IMMUNOSUPPRESSIVE AGENTS which inhibit the action of INTERLEUKINS. HN - 2022 BX - IL Inhibitor BX - Interleukin Inhibitor MH - Intersectional Framework UI - D000091702 MN - F1.145.813.339 MN - F4.96.879.757.100 MN - I1.880.453 MS - Interconnections of social categorizations such as race, class, and gender, creating overlapping and interdependent systems of discrimination or disadvantage. HN - 2022 BX - Intersectionality MH - Intestinal Failure UI - D000090124 MN - C6.405.469.462 MS - Various intestinal diseases functionally defined as having reduced intestine function requiring PARENTERAL NUTRITION. HN - 2022 MH - Iron Deficiencies UI - D000090463 MN - C18.452.565.400 MS - Deficient amounts of iron in the body as a result of blood loss, diets deficient in iron, or an iron uptake or storage disorder. AN - ANEMIA, IRON-DEFICIENCY is also available HN - 2022 BX - Hypoferritinemia BX - Iron Deficiency BX - Latent Iron Deficiency BX - Sideropenia MH - Klotho Proteins UI - D000090265 MN - D8.811.277.450.426.500 MN - D12.776.543.750.750.400.370.250 MS - Membrane bound glucuronidase enzymes that may play a role in activation of FIBROBLAST GROWTH FACTORS, and in the regulation of a variety of cell signaling pathways. HN - 2022 BX - alpha-Klotho Proteins BX - beta-Klotho Proteins MH - Kruppel-Like Factor 4 UI - D000090062 MN - D12.776.260.522.532 MN - D12.776.930.375.532 MS - A member of zinc finger-containing transcription factors that belongs to the KRUPPEL-LIKE FACTOR family, involved in the regulation of diverse cellular processes such as cell growth, proliferation, differentiation, and APOPTOSIS. HN - 2022 (1997) BX - Endothelial Kruppel-Like Zinc Finger Protein BX - Epithelial Zinc Finger Protein BX - EZF Protein BX - GKLF Protein BX - Gut-Enriched Kruppel-Like Factor BX - Klf4 Protein BX - Krueppel-Like-Factor 4 MH - Laboratories, Clinical UI - D000090464 MN - N2.278.487.205 MS - Facilities equipped to carry out CLINICAL LABORATORY TECHNIQUES. HN - 2022 FX - Clinical Laboratory Services FX - Clinical Laboratory Techniques MH - Lamellar Bodies UI - D000088502 MN - A11.284.430.214.190.500.384 MN - A11.284.430.214.190.875.190.190.472 MN - A11.284.430.214.190.875.190.880.810.375 MS - Endolysosomal organelles surrounded by multi-lamellar MEMBRANE LIPIDS. They are involved in diverse functions in storage and secretion of cellular LIPIDS. Lamellar bodies in the TYPE 2 PNEUMOCYTES produce and secrete PULMONARY SURFACTANT (e.g., DIPALMITOYL PHOSPHATIDYLCHOLINE). Lamellar bodies in the skin produce and secrete neutral lipids to provide hydrophobic barrier. Pathological accumulation of lamellar bodies are also known in lipid storage diseases (e.g.,LCAT DEFICIENCY; and HERMANSKY-PUDLAK SYNDROME). HN - 2022 BX - Lamellar Granules BX - Lamellar Lysosomes BX - Membrane Coating Granules BX - Membrane-Coating Granules BX - Odland Bodies MH - Leucine-Rich Repeat Proteins UI - D000090263 MN - D12.776.529 MS - A protein with a three-dimensional structure that forms an alpha/beta horseshoe fold. It is found in a large number of proteins with diverse functions, including INNATE IMMUNITY RESPONSE and NERVOUS SYSTEM. HN - 2022 (1997) BX - Leucine-Rich Repeat Protein BX - LRR Proteins MH - Life Course Perspective UI - D000089823 MN - F2.970.250 MS - An approach to analyze one’s life within the framework of various circumstances experienced in a given society throughout entirety of life. HN - 2022 BX - Control Balance Theory BX - Integrated Life Course Theories BX - Integrated Theories BX - Latent Trait Theories BX - Latent Trait Theory BX - Life Course Theories BX - Life Course Theory MH - Light Pollution UI - D000090465 MN - N6.850.460.505 MS - The inappropriate or excessive use of artificial lighting at night. HN - 2022 BX - Artificial Light at Night BX - Artificial Night Lighting BX - Artificial Night Sky Brightness BX - Skyglow FX - Chronobiology Disorders MH - Listening Effort UI - D000088746 MN - F2.463.593.71.375 MN - G7.888.125.375 MS - The deliberate allocation of mental resources to overcome obstacles in goal pursuit when carrying out a task, with listening effort applied more when tasks involved listening. (From Pichora-Fuller et al.2016) HN - 2022 MH - Livedoid Vasculopathy UI - D000090122 MN - C14.907.355.830.573 MN - C17.800.862.406 MS - A rare cutaneous thrombotic disease due to occlusion of dermal vessels. It is characterized by purpuric maculae and ulcerations especially during summer which form scars called atrophie blanche. It is more associated with other syndromes (e.g., PROTEIN C DEFICIENCY; HYPERHOMOCYSTEINEMIA). HN - 2022 BX - Livedo Reticularis with Summer Ulceration BX - Livedoid Vasculitis MH - Low-Value Care UI - D000090222 MN - N3.219.151.725 MS - Medical services, including tests and procedures, that should not be performed given their potential for harm or the existence of comparably effective and often less expensive alternatives. HN - 2022 MH - Luciferins UI - D000090562 MN - D2.578 MS - Organic substances found in organisms that generate BIOLUMINESCENCE such as FIREFLY LUCIFERIN that produces light when oxidized to the excited oxyluciferin by the action of the enzyme LUCIFERASE. HN - 2022 BX - Luciferin MH - Mandibular Canal UI - D000088263 MN - A2.835.232.781.324.502.632.365 MS - Internal aspect of the mandible from the MENTAL FORAMEN to the mandibular foramen which serves as the conduit for the INFERIOR ALVEOLAR NERVE and the inferior alveolar artery and vein. Bifid and trifid mandibular canals are normal anatomical variants. HN - 2022 BX - Bifid Mandibular Canal BX - Inferior Alveolar Canal BX - Inferior Alveolar Foramen BX - Trifid Mandibular Canals MH - Mannose Receptor UI - D000090323 MN - D12.776.503.280.508 MN - D12.776.503.311.750 MN - D12.776.543.750.02 MS - A member of a family of endocytic receptors. Highly expressed on human macrophages, involved in regulating endocytosis, phagocytosis, and immune responses. HN - 2022 (1982) BX - CD206 Antigen BX - Cluster of Differentiation 206 BX - Mannose Receptors BX - Mannose-Fucose Receptor BX - Mannosyl-Fucosyl Receptor BX - MRC1 Protein BX - Receptor, Mannose MH - Mass Gatherings UI - D000090522 MN - F1.145.813.542 MN - F1.145.875.281.500 MS - Organized or spontaneous events where the number of people attending is sufficient to strain the planning and response resources of the community hosting the event. (WHO, 2008). These events include the gathering of people as the result of natural disasters or conflict. HN - 2022 BX - Collective Behavior BX - Group Behavior BX - Public Demonstrations MH - Mast Cell Activation Disorders UI - D000090362 MN - C20.762 MS - A spectrum of primary, secondary, and idiopathic disorders involving MAST CELLS and characterized by an aberrant release of mast cell mediators which result in multiple and variable inflammatory and allergic symptoms. These disorders are associated with various mutations in tyrosine kinase KIT (PROTO-ONCOGENE PROTEINS C-KIT) and other genes, underlying conditions, and responses to allergic or non-allergic triggers of mast cell stimulation and degranulation such as local anesthetics, lactam antibiotics, muscle relaxants, specific foods, environmental toxins, physical conditions such as vibration, cold, pressure, and stress. HN - 2022; for MAST CELL ACTIVATION DISEASE use MASTOCYTOSIS 2018-2021 BX - Clonal Mast Cell Proliferation Disorders BX - Mast-Cell Disease BX - Monoclonal Mast Cell Activation Syndrome BX - Primary Mast Cell Activation Disorders MH - Mast Cell Activation Syndrome UI - D000090267 MN - C20.762.500 MS - A clinically and genetically heterogeneous group of mast cell disorders in which there is aberrant release of mast cell mediators with little to no accompanying proliferation of MAST CELLS. HN - 2022; for MAST CELL ACTIVATION SYNDROME use MASTOCYTOSIS 2018-2021 BX - Idiopathic Mast Cell Activation Disorder BX - nc-MCAS BX - Non-Clonal Mast Cell Activation Disorder BX - Non-Clonal Mast Cell Activation Syndrome BX - Nonclonal Mast Cell Activation Syndrome MH - Medication Review UI - D000090143 MN - N4.452.528.467 MN - N4.590.659 MS - A structured evaluation of a patient‘s medicines with the aim of optimizing medicines use and improving health outcomes, detecting drug related problems and recommending interventions. HN - 2022 MH - Medicine, Persian UI - D000091182 MN - E2.190.488.708 MN - I1.76.201.450.654.694 MS - Traditional concepts of medicine and associated methods reflected in medicine in PERSIA. AN - traditional practice only; not for modern medicine in Iran (= MEDICINE + IRAN); MEDICINE, ARABIC is also available; follow author's terminology; Avicenna (also called Ibn Sina)is indexed as Avicenna + BIOGRAPHY + HISTORY OF MEDICINE, MEDIEVAL HN - 2022 BX - Ancient Iranian Medicine BX - Iranian Traditional Medicine BX - Medicine, Persian Traditional BX - Persian Traditional Medicine MH - Memory B Cells UI - D000091245 MN - A11.63.438.450.650 MN - A11.118.637.555.567.269.500 MN - A11.118.637.555.567.550.450.650 MN - A11.118.637.555.567.562.200.650 MN - A15.145.229.637.555.567.550.450.650 MN - A15.145.229.637.555.567.562.200.650 MN - A15.382.32.438.450.650 MN - A15.382.490.555.567.562.450.650 MS - A subset of activated B cells generated in response to primary immune challenge or immunization which are capable of giving rise to antibody-secreting cells upon re-challenge (see IMMUNOLOGIC MEMORY). Memory B cells feature many discrete properties indicative of differentiation through ISOTYPE SWITCHING and/or IMMUNOGLOBULIN SOMATIC HYPERMUTATION for rapid and robust recall of specific antibody responses. HN - 2022 BX - Memory B-Lymphocytes MH - Memory T Cells UI - D000091246 MN - A11.118.637.555.567.269.750 MN - A11.118.637.555.567.569.500.75 MN - A15.145.229.637.555.567.550.500.75 MN - A15.145.229.637.555.567.569.500.75 MN - A15.382.490.555.567.550.500.75 MN - A15.382.490.555.567.569.500.75 MS - A subset of activated T cells generated in response to primary immune challenge or immunization upon re-challenge (see IMMUNOLOGIC MEMORY). Memory T cells feature many discrete properties indicative of various differentiation such as expression pattern of CCR7 RECEPTORS and can be divided into central memory and effector memory T cells. HN - 2022 BX - Central Memory T Cells BX - Effector Memory T Cells BX - Memory T Lymphocytes BX - Tissue Resident Memory T Cells BX - Virtual Memory T Cells MH - Mentalization-Based Therapy UI - D000088042 MN - F4.754.539 MS - Mentalization-based therapy (MBT) is a type of long-term psychotherapy that is based on the use of MENTALIZATION. HN - Mentalization 2019-2021 BX - Mentalization Based Therapy BX - Mentalization-Based Treatment MH - Mesothelin UI - D000090204 MN - D12.644.360.410 MN - D12.776.395.550.448.550 MN - D12.776.476.410 MN - D12.776.543.484.500.588 MN - D12.776.543.550.418.550 MN - D23.50.301.609 MS - An ANTIGEN present on the surface of certain types of normal cells and overexpressed in several human tumors, including OVARIAN CANCER. HN - 2022 BX - CAK-1 Antigen BX - Megakaryocyte Potentiating Factor MH - Metallothionein 3 UI - D000090023 MN - D12.776.556.670.500 MN - D12.776.631.540 MS - A metallothionein that exhibits neuroinhibitory activity and is involved in the repair of neuronal damage. HN - 2022 (1993) BX - Growth Inhibitory Factor BX - Metallothionein III BX - Metallothionein-III BX - MT-III MH - Microaggression UI - D000088828 MN - F1.145.813.45.500 MS - Brief verbal, behavioral, or situational indignities that communicate hostile, derogatory, or negative slights or insults. It may may be intentional or implicit. Three subtypes have been identified: microassaults, which are purposefully discriminatory actions; microinsults, which are subtle snubs that devalue a person’s identity; and microinvalidations, which are unintentional exclusions or negations of an individual’s thoughts. (dictionary.apa.org/microaggression 12/30/2020) HN - 2022 MH - Microneme UI - D000088462 MN - A11.284.430.214.190.875.190.880.810.500 MS - Secretory organelle in the apical complex of parasitic phylum APICOMPLEXA (e.g., TOXOPLASMA GONDII). Microneme plays a role in junction formation between the parasite and the host cell by releasing micronemal proteins, which bind to receptors on the host cell surface enabling parasite attachment. HN - 2022 BX - Sarconeme MH - MINOCA UI - D000088442 MN - C14.280.647.500.328 MN - C14.907.585.500.422 MN - C23.550.513.355.750.328 MN - C23.550.717.489.750.328 MS - Myocardial infarction in the absence of obstructive coronary artery disease. CORONARY CIRCULATION disruption is due to various other factors such as ATHEROSCLEROTIC PLAQUE and CORONARY VASOSPASM. HN - 2022 BX - Myocardial Infarction and Non-obstructed Coronary Arteries BX - Myocardial Infarction and Nonobstructed Coronary Arteries BX - Myocardial Infarction with Non-obstructive Coronary Arteries BX - Myocardial Infarction with Nonobstructive Coronary Arteries MH - Mirror Movement Therapy UI - D000088762 MN - E2.831.535.680 MS - Rehabilitation therapy in which a mirror is placed between the arms or legs so that the image of a moving non-affected limb gives the illusion of normal movement in the affected limb. This stimulates different brain regions for movement, sensation, and pain. (www.cochrane.org/CD008449 access 12/28/2020) HN - 2022 BX - Mirror Therapy MH - Mitochondrial Precursor Protein Import Complex Proteins UI - D000090622 MN - D5.500.469 MN - D5.500.890.563 MN - D12.776.543.585.475.594 MN - D12.776.575.750.594 MS - Multiprotein complexes that mediate import and sorting of mitochondrial preproteins into one of the four mitochondrial subcompartments: the outer membrane, the intermembrane space, the inner membrane, and the matrix. Mitochondrial protein import machinery includes translocase of the outer membrane (TOM) complex, translocases of the inner membrane (TIM) complex, beta‐barrel pathway complex, the mitochondrial intermembrane space import and assembly (MIA) pathway complex, carrier proteins of the inner membrane and the TIM23 complex and sorting and assembly machinery (SAM) complex. HN - 2022(2006) BX - MIA Complex BX - MIM Complex BX - Mitochondrial Import Complex BX - Mitochondrial Intermembrane Space Import and Assembly Complex BX - Mitochondrial Precursor Protein Import Machinery Proteins BX - Mitochondrial Preprotein Translocases BX - Mitochondrial Protein Import Machinery Proteins BX - SAM Complex BX - Sorting and Assembly Machinery Complex BX - TIM Complex BX - TIM23 Complex BX - TIMM Complex BX - TOM Channel BX - TOM Complex BX - TOM Translocase BX - TOMM Complex BX - TOMM Machinery BX - Translocase of the Inner Membrane Complex BX - Translocase of the Inner Mitochondrial Membrane Complex BX - Translocase of the Outer Membrane Complex BX - Translocase Outer Mitochondrial Membrane BX - Translocases of the Inner Membrane 23 Complex BX - Translocases of the Inner Membrane Complex MH - Molybdenum Cofactors UI - D000090006 MN - D8.211.532 MS - Enzyme co-factors that contain MOLYBDENUM. They play an essential role in a variety of cellular REDOX reactions. HN - 2022 BX - Molybdenum-Containing Cofactors BX - Pterin-based Molybdenum Cofactor BX - Pterin-based Molybdenum Cofactors MH - mRNA Vaccines UI - D000087503 MN - D12.776.828.868.228.500 MN - D20.215.894.865.450.500 MN - D23.50.865.450.500 MS - Vaccines formulated with recombinant mRNAs which are taken up by the host cells that translate the mRNA and present the translated proteins to the immune system as antigens in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigen. HN - 2022 BX - Messenger RNA Vaccines BX - Naked RNA Vaccines BX - RNA Vaccines MH - MTOR Inhibitors UI - D000091203 MN - D27.505.519.389.755.750 MN - D27.505.696.477.656.625 MN - D27.505.954.248.538 MS - Agents that inhibit the activity of the mechanistic target of RAPAMYCIN, which is a protein kinase. HN - 2022 BX - Rapalogs MH - mu-Crystallins UI - D000090803 MN - D8.811.682.662.436 MN - D12.776.306.366.888 MS - A subclass of crystallins expressed highly in lens of diurnal Australian MARSUPIALS and in neural tissue, muscle, and kidney in humans. It is not a structural protein accounting for the transparency of the human lens unlike other crystallins but instead plays a role in thyroid hormone bioavailability. It is also a cerebral ketimine reductase which reduces cyclic imines (e.g., DELTA(1)-PIPERIDINE-2-CARBOXYLIC ACID; CYSTATHIONINE KETIMINE and LANTHIONINE KETIMINE) in mammalian brain. Mutations in mu-crystallins are associated with an autosomal dominant NONSYNDROMIC DEAFNESS. HN - 2022(1992) BX - CRYM Protein BX - Crystallin mu BX - Ketimine Reductase mu-Crystallin BX - NADP-Regulated Thyroid Hormone Binding Protein BX - THBP Protein MH - Multidrug Resistance-Associated Protein 2 UI - D000089762 MN - D12.776.157.530.100.304.750 MN - D12.776.157.530.450.74.500.500.500.750 MN - D12.776.543.585.100.304.750 MN - D12.776.543.585.450.74.500.500.500.750 MS - An ATP-BINDING CASSETTE TRANSPORTERS subfamily protein that is localized on the canalicular membrane of HEPATOCYTES, as well as on the apical membrane of EPITHELIAL CELLS of the DUODENUM, JEJUNUM and PROXIMAL RENAL TUBULE. HN - 2022 BX - ABCC2 Protein BX - Canalicular Multispecific Organic Anion Transporter BX - CMOAT BX - CMOAT Protein BX - CMOAT Transport Protein BX - MRP2 Protein, Multidrug Resistance BX - MRP2 Transport Protein BX - Multidrug Resistance Protein MRP2 BX - Multidrug-Resistance Associated Protein 2 MH - Myofascial Release Therapy UI - D000089803 MN - E2.190.599.750.750.750 MN - E2.779.867.880.750.750 MN - E2.831.535.867.880.750.750 MS - A massage therapy which focuses on releasing MUSCLE TIGHTNESS often used to relieve muscular pain from myofascial tissues (e.g., MYOFASCIAL PAIN SYNDROME). HN - 2022 BX - Myofascial Release BX - Myofascial Release Treatment BX - Myofascial Treatment MH - Nanoparticle Drug Delivery System UI - D000090783 MN - D26.255.260.750 MN - E2.319.300.380.800 MS - Engineered NANOPARTICLES with unique physiochemical properties which improve drug BIOAVAILABILITY and site specific drug delivery. HN - 2022 BX - Nano Delivery System BX - Nano Drug Delivery Systems BX - Nano-Drug Delivery System BX - Nanoparticle Based Drug Delivery System BX - NDDSs MH - Neighborhood Characteristics UI - D000091542 MN - I1.880.853.500.525 MN - N1.224.791.775 MN - N6.850.505.400.800.775 MS - Characteristics that may describe the demographic, social, built environment, or economic characteristics of a geographic area in which people live and can affect health and well-being of neighborhood residents. Neighborhood environments include the physical environment (unsafe air/water), built environment (sidewalks/greenspace) and the social environment (safety, sense of community). AN - specify geographic location if pertinent HN - 2022 BX - Neighborhood Disadvantage BX - Neighborhood Safety MH - Network Pharmacology UI - D000091484 MN - E5.295.500 MS - A systems-based pharmacologic discovery process used to predict the multiple targets of multiple drugs in a complex mixture such as CHINESE HERBAL DRUGS. It involves analytical detection of chemicals plus prediction of pharmacologic activity and protein targets for each compound in the mixture and aggregating the net physiological effect. HN - 2022 BX - Drug-Target Network BX - Systematic Pharmacology BX - Systems Pharmacology FX - Polypharmacology FX - Systems Biology MH - Neuro-Oncological Ventral Antigen UI - D000090682 MN - D12.776.157.725.441 MN - D12.776.631.611 MN - D12.776.664.962.448 MS - They are RNA-BINDING PROTEINS involved in mRNA processing. These are essential in gene regulation, including splicing, translation, transport, stability, and degradation of RNA. HN - 2022 (1993) BX - Antigens, Ri BX - Neuro-Oncological Ventral Antigen 1 BX - Neuro-Oncological Ventral Antigen 2 BX - Nova 1 BX - Nova Antigen BX - Nova Protein BX - Nova-1 Antigen BX - Paraneoplastic Ri Antigen BX - Paraneoplastic Ri Antigen, 55 KDA BX - Ri Antigen BX - Ventral Neuron-Specific Protein 1 MH - Neuroinflammatory Diseases UI - D000090862 MN - C10.586 MN - C23.550.470.544 MS - Diseases characterized by inflammation of the nervous tissue. AN - general or unspecified; prefer specifics HN - 2022 BX - Neuroinflammation BX - Neuroinflammatory Disorders MH - Nitrate Transporters UI - D000091285 MN - D12.776.157.530.450.74.375 MN - D12.776.543.585.450.74.375 MN - D12.776.765.519 MS - Plant proteins that participate in the active uptake of NITRATE from soil and its transport throughout the plant. HN - 2022 (1993) BX - CrnA Nitrate Transporter, Aspergillus nidulans BX - CrnA Protein, Aspergillus nidulans BX - Nitrate Transporter BX - Nitrate Transporter 2 Protein, Glycine max BX - Nitrate Transporter 2 Protein, Plant BX - Nitrate-Nitrite Antiporter BX - NRT2 Protein, Glycine max BX - Nrt2 Protein, Plant BX - NTL1 Protein, Arabidopsis MH - Non-Radiographic Axial Spondyloarthritis UI - D000089202 MN - C5.116.900.853.625.800.744.250 MN - C5.550.69.340.250 MN - C5.550.114.865.800.744.250 MS - Chronic inflammatory conditions affecting the axial joints which cannot be detectable on x-rays. It is characterized by pain, stiffness of joints and inflammation. Non-radiographic axial spondyloarthritis can have symptoms onset before the age of 45 and progress to more severe ANKYLOSING SPONDYLITIS over time. HN - 2022 BX - Nr-axSpA MH - Nonagenarians UI - D000088642 MN - M1.60.116.100.80.625 MS - Persons 90 years of age and older. HN - 2022 MH - Nordic Walking UI - D000088783 MN - G11.427.410.568.900.813 MN - G11.427.410.698.277.937.250 MN - I3.350.937.250 MN - I3.450.642.845.940.500 MS - Form of brisk walking, utilizing walking poles, which actively engages the trunk and upper limbs during walking, maintaining the natural gait, while the hands are performing an open–close cycle in an alternating manner. HN - 2022 BX - Pole Walking MH - Nuclear Bodies UI - D000088202 MN - A11.284.430.106.279.345.574 MS - Dynamic intranucleoplasmic membraneless structures which concentrate various nuclear factors. Nuclear bodies exchange components with NUCLEOPLASM and participate in various RNA metabolisms unlike nuclear INCLUSION BODIES which aggregate most often foreign or inactive pathological biomolecules. HN - 2022 BX - Cleavage Bodies BX - Cleavage Body BX - Histone Locus Bodies BX - Histone Locus Body BX - Interchromatin Granule BX - Interchromatin Granules BX - Nuclear Dicing Bodies BX - Nuclear Dicing Body BX - Sphere Organelle BX - Sphere Organelles BX - Transcriptional Condensates BX - Transcriptional Droplets MH - Nuclear Speckles UI - D000088203 MN - A11.284.430.106.279.345.574.813 MS - Membraneless intranucleoplasmic subcompartments or nuclear domains in which proteins related to RNA metabolism (e.g., SPLICING FACTORS) are dynamically localized. HN - 2022 BX - Interchromatin Granule Clusters BX - Omega Speckles BX - Splicing Speckles MH - Nucleic Acid-Based Vaccines UI - D000087504 MN - D12.776.828.868.228 MN - D20.215.894.865.450 MN - D23.50.865.450 MS - Vaccines formulated with nucleic acids specific for a target antigen. They are designed to induce antibody production against the target by host. HN - 2022(1997) BX - Nucleic Acid Vaccine BX - Nucleic Acid Vaccines BX - Polynucleotide Vaccine BX - Polynucleotide Vaccines MH - Nucleophosmin UI - D000090243 MN - D12.776.660.694 MS - Predominantly localized in the CELL NUCLEOLUS, involved in diverse cellular processes such as ribosome biogenesis, cytoplasmic-nuclear trafficking, centrosome duplication, and regulation of p53. HN - 2022 (1981) BX - NO38 Protein BX - Nucleolar Phosphoprotein B23 BX - Nucleolar Protein B23 BX - Nucleophosmid BX - Numatrin BX - Phosphoprotein B23, Nucleolus BX - Protein B23 MH - Octogenarians UI - D000087742 MN - M1.60.116.100.80.750 MS - Persons 80 to 89 years of age. HN - 2022; OCTOGENARIANS was CENTENARIAN, NONAGENARIAN, & OCTOGENARIAN 1987-95, was AGED, 80 AND OVER 1987-2020 MH - Opsonization UI - D000088362 MN - G4.417.350.772 MN - G9.188.665.750 MN - G12.287.70.500 MN - G12.450.564.809.750 MN - G12.688.750 MS - The process of recognizing and targeting particles by binding with OPSONINS (e.g., IgM, C1 and IgG) for phagocytosis or for antibody-dependent cell cytotoxicity. HN - 2022 BX - Opsonophagocytosis FX - Opsonin Proteins MH - Organocopper Compounds UI - D000091343 MN - D2.257.133 MN - D2.691.319 MS - Organic compounds that contain COPPER as an integral part on the molecule. HN - 2022 BX - Copper-Cuprous Oxide BX - Organic-Copper Complex BX - Organo-Copper Complexes BX - Organo-Copper Compounds BX - Organocopper Complexes MH - Orthorexia Nervosa UI - D000088102 MN - F3.400.860 MS - An eating disorder that is characterized by the pathological obsession with HEALTHY EATING. HN - 2022 BX - Obsessive Healthy Eating BX - Orthorexia FX - Diet, Healthy MH - Orycteropodidae UI - D000091123 MN - B1.50.150.900.649.313.250.125 MS - An order of placental mammals in the superorder AFROTHERIA found in Africa. It has single species Orycteropus afer. HN - 2022(1998) BX - Aardvarks BX - Orycteropus BX - Orycteropus afer MH - Ostracism UI - D000091488 MN - F1.145.813.781.500 MN - I1.880.853.748.595 MS - An extreme form of rejection in which one is excluded and ignored in the presence of others. HN - 2022 MH - Overdiagnosis UI - D000088522 MN - E1.505 MN - N2.421.562 MN - N5.300.565 MS - The labeling of a person with a disease or abnormal condition that would not have caused the person harm if left undiscovered, creating new diagnoses by medicalizing ordinary life experiences, or expanding existing diagnoses by lowering thresholds or widening criteria without evidence of improved outcomes. Individuals derive no clinical benefit from overdiagnosis although they may experience physical, psychological or financial harm. HN - 2022(2016) BX - Over-Diagnosis BX - Pseudodisease, Over-Diagnosed BX - Pseudodisease, Overdiagnosed MH - Overtreatment UI - D000088922 MN - N2.421.380.450.188 MN - N5.300.150.395.450.188 MS - Remedial treatment or preventive procedures of a disease which is done too frequently or excessively often from OVERDIAGNOSIS. HN - 2022(2016) BX - Over-treatment MH - Oxygen Saturation UI - D000089382 MN - G3.707 MS - Extent to which HEMOGLOBIN is saturated with OXYGEN typically as measured in arterial blood. It can be measured by various methods (e.g., PULSE OXYMETER, blood gas analysis). A low blood oxygen saturation level indicates a condition called HYPOXEMIA. HN - 2022 BX - Blood Oxygen Levels BX - Saturation of Peripheral Oxygen BX - SpO2 MH - Paraspeckles UI - D000088242 MN - A11.284.430.106.279.345.574.844 MS - Nuclear bodies in which architectural LONG NCRNAS (e.g., NEAT1) sequester various regulatory proteins regulating gene expression including RNA modification (e.g., A-to-I RNA EDITING) and MICRORNAS maturation. HN - 2022 MH - PCSK9 Inhibitors UI - D000091362 MN - D27.505.519.186.71.202.685 MN - D27.505.519.389.745.800.506 MN - D27.505.954.557.500.202.685 MS - Agents that inhibit Proprotein Convertase Subtilisin/Kexin Type 9 (see PROPROTEIN CONVERTASE 9 (PCSK9)), an enzyme that plays an important role in the degradation of the LDL receptors. It favors LDL catabolism and reduces plasma LDL-cholesterol (LDL_C) level. HN - 2022 BX - PCSK9 Inhibitors Cardiovascular BX - PCSK9 Inhibitors, Cardiovascular MH - Perceived Discrimination UI - D000091563 MN - F1.145.813.629.594 MN - F2.463.593.752.250 MS - Perception of being treated badly or unfairly on the basis of race, ethnicity, gender, age, religion, physical appearance, sexual orientation, or other characteristics. This includes perceived discrimination in health care settings. HN - 2022 MH - Persistent Infection UI - D000088562 MN - C1.645 MN - C23.550.291.902 MS - Infection which lasts for a long period with continuous display of clinical features. Persistent infection arises due to inability of host cells to clear primary infections completely. When persistent infections are cleared so that infection symptoms are under control they are often referred to as chronic infections. LATENT INFECTIONS are infections in which manifestation of clinical symptoms appear later. AN - coordinate with specific infection HN - 2022 BX - Chronic Infection BX - Long Term Infection FX - Chronic Disease MH - Phase Variation UI - D000090502 MN - G5.365.693 MS - An adaptive mechanism used by microbes to avoid detection by the host or adapt to changes in environment by randomly and rapidly switch on and off of a gene by various mechanisms. between on and off phases. For instance, drug tolerant MYCOBACTERIUM TUBERCULOSIS arises though rapid reversible mutations in the glpK gene through phase variation. HN - 2022 BX - Phase-Variable Regulons BX - Phasevarions MH - Planctomycetes UI - D000090643 MN - B3.440.619 MS - A phylum of gram-negative bacteria with complex cytoplasmic membrane invaginations and crateriform structures of outer membrane. Members living in anoxic waters and sediments carry out ANAEROBIC AMMONIA OXIDATION. HN - 2022 BX - Planctomycetaeota BX - Planctomycetota MH - Plant Cone UI - D000090342 MN - A18.24.625 MS - Any conical shaped aerial plant structure with scales or bracts arranged spirally around axis. It includes familiar seed cones of PINE TREE and other GYMNOSPERMS, pollen cones (e.g., microstrobilus), spore capsules in HORSETAIL and CLUBMOSS and mature female catkins or seed cones of ALDER and BIRCH trees. Cone morphology is important in gymnosperm classification. HN - 2022 BX - Catkins BX - Cones, Plant BX - Microstrobili BX - Microstrobilus BX - Pine Cone BX - Plant Cones BX - Seed Cones BX - Spore Cones BX - Strobili BX - Strobilus MH - Plant Senescence UI - D000091385 MN - G7.345.625.937 MN - G15.589.500 MS - In plants, similarly as in animals, an age-dependent irreversible process of changes leading to the arrest of CELL DIVISION and/or PROGRAMMED CELL DEATH. HN - 2022 BX - Flower Senescence BX - Leaf Senescence BX - Plant Aging BX - Plant Cellular Replicative Senescence BX - Plant Cellular Senescence MH - Predatory Journals as Topic UI - D000090282 MN - L1.178.682.829.678.500 MS - Works about medical journals that publish articles online with little or no peer review, low academic standards, and little credibility. (from Can Fam Physician. 2019 Feb; 65(2):92). HN - 2022 BX - Predatory Journals MH - Primary Visual Cortex UI - D000087642 MN - A8.186.211.200.885.287.500.571.735.500 MN - A8.186.211.200.885.287.500.814.953.500 MS - An area comprised of parts of OCCIPITAL LOBE and the CALCARINE SULCUS of the visual cortex in humans with direct connectivity to the LATERAL GENICULATE NUCLEUS. It is the end organ where visual stimuli are received in the visual cortex. AN - do not confuse entry term STRIATE CORTEX with CORPUS STRIATUM (basal ganglia) HN - 2022(1979) BX - Area V1 BX - Brodmann Area 17 BX - Brodmann's Area 17 BX - Calcarine Cortex BX - Cortical Area V1 BX - Striate Cortex BX - Visual Cortex V1 MH - Processing Bodies UI - D000088142 MN - A11.284.430.214.190.500.780.500 MN - A11.284.430.214.190.875.190.190.384.500 MS - Cytoplasmic RNP granules constitutively found in eukaryotic cells. Various proteins related to RNA regulation including RNA decay are found in P-bodies. P-bodies and STRESS GRANULES both sequester inactive mRNPs via different pathways. In P-bodies mRNAs from the stalled translational machinery are deadenylated and condensed for sequestration. HN - 2022 BX - Glycine-Tryptophan Protein of 182 KDa Bodies BX - GW-Bodies BX - P Bodies BX - P-Bodies MH - Prohibitins UI - D000091402 MN - D12.776.575.844 MS - Ubiquitously expressed conserved proteins associated with multiple functions including APOPTOSIS; CELL PROLIFERATION, regulations of various immune and mitochondrial functions, and cellular stress responses. Prohibitin 1 and prohibitin 2 form a ring-shaped complex in the INNER MITOCHONDRIAL MEMBRANE. HN - 2022(1991) BX - Prohibitin MH - Prolonged Grief Disorder UI - D000090382 MN - F1.470.142.555 MS - Severe and disabling grief reactions that do not remit in the 12 months after the death of a significant other. The core of the diagnosis includes persistent yearning or missing the deceased, and preoccupation with the circumstance of the death. (Carmassi, Clinical Handbook of Bereavement and Grief Reactions, 2018) HN - 2022 MH - Promyelocytic Leukemia Nuclear Bodies UI - D000088182 MN - A11.284.430.106.279.345.574.875 MS - Spherical intranuclear membraneless bodies nucleated by PROMYELOCYTIC LEUKEMIA PROTEIN and various other proteins containing small ubiquitin-related modifier (SUMO) interaction motif (SIM) and/or sumoylated proteins (e.g., Sp100 protein). Promyelocytic leukemia nuclear bodies regulate posttranslational modifications of partner proteins (e.g., SUMOYLATION) which in turn lead to modulation of various biological processes. HN - 2022 BX - PML Bodies BX - PML NBs BX - PML Nuclear Bodies BX - Promyelocytic Leukemia Nuclear Body BX - Promyelocytic Leukemia Protein Bodies BX - Promyelocytic Leukemia Protein Body MH - Protein Glutamine gamma Glutamyltransferase 2 UI - D000091345 MN - D8.811.913.50.200.800.650 MS - Calcium-dependent acyltransferase that catalyzes cross-linking of proteins at a GLUTAMINE in one chain with primary amine such as in LYSINE in another chain. In addition it can also accept monoamine substrates to catalyze post-translational modifications (e.g., protein serotonylation). AN - distinguish from GAMMA-GLUTAMYLTRANSPEPTIDASE which is involved with glutathione metabolism HN - 2022(1999) BX - TGM2 Proteins BX - Tissue Transglutaminase BX - Tissue-Type Transglutaminase BX - Transglutaminase 2 BX - Transglutaminase C BX - Transglutaminase II MH - Protein Kinase D2 UI - D000091283 MN - D8.811.913.696.620.682.700.750 MN - D12.776.476.563.750 MS - A SERINE-THREONINE PROTEIN KINASE that is activated in response to OXIDATIVE STRESS. HN - 2022 (2001) BX - PKD2 Enzyme BX - PRKD2 Protein MH - Proto-Oncogene Mas UI - D000090063 MN - D12.776.543.750.695.47.313 MN - D12.776.543.750.750.130.375 MN - D12.776.624.664.700.166 MS - A protein that is encoded by the MAS1 gene. It is a receptor for ANGIOTENSIN 1-7 and acts as an antagonist of ANGIOTENSIN-2 TYPE 1 RECEPTOR. HN - 2022 (1986) BX - C-Mas Protein BX - II-Proto-Oncogene Proteins, Cellular BX - Mas Protein BX - Mas1 Protein BX - Proto-Oncogene Protein Mas BX - Proto-Oncogene Proteins C-Mas-1 MH - Protocadherins UI - D000091363 MN - D12.776.395.550.200.200.750 MN - D12.776.543.550.200.200.750 MN - D23.50.301.350.200.750 MS - Members of cadherin superfamily involved in cell adhesion and cell-cell interactions in neural development. They are subdivided into clustered (cPcdhs) and non-clustered protocadherin (ncPcdhs) depending whether their genes are tandemly arranged in vertebrates. HN - 2022 BX - Cadherin-Related Neuronal Receptors BX - Clustered Pcdhs BX - Clustered Protocadherins BX - cPcdhs BX - ncPcdhs BX - Non-Clustered Pcdhs BX - Non-Clustered Protocadherins MH - Psychogenic Nonepileptic Seizures UI - D000091323 MN - C10.597.742.357 MN - C23.888.592.742.357 MS - Seizures caused by psychological factors without electrophysiological epileptic changes. HN - 2022 BX - Psychogenic Pseudoseizure MH - Psychological First Aid UI - D000088782 MN - F4.408.525.500 MS - Early psychosocial intervention approach used during or after traumatic life events as disasters, accidents, terrorist attacks causing negative effects on individual and/or society. It focuses on determining basic physical and mental needs of individuals in major events. HN - 2022 MH - rab7 GTP-Binding Proteins UI - D000090802 MN - D8.811.277.40.330.300.400.400.600 MN - D12.776.157.325.515.400.600 MN - D12.776.476.338.400.400.600 MS - A small family of rab GTP-binding proteins that play a key role in membrane trafficking in the late endocytic and autophagic pathways. HN - 2022(2000) BX - Rab7 Proteins BX - ras-Related Protein Rab-7 MH - Radiation Fibrosis Syndrome UI - D000087525 MN - C23.550.355.663 MN - C26.733.685 MN - G1.750.748.500.685 MN - N6.850.460.350.850.500.222 MN - N6.850.810.300.360.222 MS - Radiation-induced fibrosis due to increased production of FIBRIN. Its symptoms include CERVICAL DYSTONIA, difficulty with speech and swallowing, swelling in the radiation field and TRISMUS. HN - 2022(1994) BX - Fibrosis, Radiation BX - Radiation Fibrosis BX - Radiation-Induced Fibrosis MH - Rapid On-site Evaluation UI - D000090044 MN - N4.590.874.500.750 MS - A rapid laboratory service provided onsite at clinical settings (e.g., DIAGNOSTIC IMAGING suites) typically for cytomorphologic features on FINE-NEEDLE ASPIRATION. HN - 2022 BX - ROSE Techniques FX - Endoscopic Ultrasound-Guided Fine Needle Aspiration MH - Reelin Protein UI - D000091042 MN - D8.811.277.656.300.760.753 MN - D8.811.277.656.959.350.753 MN - D12.776.395.550.200.250.760 MN - D12.776.860.300.784 MN - D23.50.301.350.663 MS - It is an EXTRACELLULAR MATRIX serine protease that plays an important role in the development of the central nervous system. It regulates neuronal migration and microtubule function. HN - 2022 (1995) BX - Reeler Protein BX - RELN Protein MH - Respiratory Aerosols and Droplets UI - D000088343 MN - A12.200.617 MN - A12.207.876 MS - Physiological aerosols and droplets expelled during coughing, sneezing, speaking and exhalation. Depending on the size, aerodynamic distribution or concentration they may play a role in transmission of infectious respiratory diseases. HN - 2022 BX - Exhaled Bio-Aerosols BX - Exhaled Biological Aerosols BX - Expiratory Droplet Nuclei BX - Infectious Aerosols BX - Respiratory Aerosol BX - Respiratory Aerosols BX - Respiratory Droplet BX - Respiratory Droplets BX - Respiratory Droplets and Aerosols MH - Reynoutria UI - D000089962 MN - B1.875.800.575.912.250.825.569 MS - Genus of flowering herbaceous perennial plants and vines in the family Polygonaceae. Some sources include plants formerly classified under Fallopia here under Reynoutria. HN - 2022 BX - Fallopia japonica × Fallopia sachalinensis BX - Fallopia × bohemica BX - Reynoutria bohemica BX - Reynoutria × bohemica MH - Ribosomal Protein L3 UI - D000090822 MN - D12.776.835.965 MS - It is a ribosomal protein that plays a crucial role in protein synthesis. HN - 2022 (1981) BX - L3 Ribosomal Protein MH - Ribosomal Protein S9 UI - D000091243 MN - D12.776.835.982 MS - It is a protein that encodes a RIBOSOMAL PROTEIN which is a component of the 40S subunit. It belongs to the S4P family of ribosomal proteins. HN - 2022 (1981) BX - S9 Ribosomal Protein MH - Rugby UI - D000087402 MN - I3.450.642.845.608 MS - Team sport game played on a rectangular field with an oval ball by two teams of 15 players (in Rugby Union Play) or 13 players (in Rugby League Play). HN - 2022(1990) BX - Rugby, League Play BX - Rugby, Union Play MH - Salvia hispanica UI - D000089945 MN - B1.875.800.575.912.250.583.520.922.375 MS - A plant species of the Salvia genus known for its seeds which are used in foods and supplements. Common name chia sometimes includes Salvia columbariae. HN - 2022 BX - Chia Plant BX - Salvia columbariae MH - Schizophrenia, Treatment-Resistant UI - D000090663 MN - F3.700.750.650 MS - A subset of schizophrenia with an inadequate response in target symptoms following treatment with two or more ANTIPSYCHOTICS. HN - 2022 BX - Refractory Schizophrenia BX - Treatment-Resistant Schizophrenia MH - Secretome UI - D000089282 MN - A12.895 MN - G3.500.500 MS - The set of all the soluble factors and extracellular vesicles secreted into the extracellular space by cells, or an organ or organism. In some studies the secretome only refers to the proteins secreted into the extracellular space. HN - 2022 BX - Protein Secretome BX - Secretomes MH - Self-Compassion UI - D000087342 MN - F1.752.747.792.813 MN - F2.463.551.500 MS - Being kind and understanding toward oneself in times of pain or failure, perceiving one's own suffering as part of a larger human experience, and holding painful feelings and thoughts in mindful awareness. (from Rev General Psychology, 15(4), 289–303. https://doi.org/10.1037/a0025754 accessed 8/11/2020) HN - 2022 BX - Self-Forgiveness MH - Senescence-Associated Secretory Phenotype UI - D000089262 MN - G4.43.445 MN - G7.345.124.130.445 MS - A paracrine pro-inflammatory phenotype developed in senescing cells. The senescence-associated secretory phenotype (SASP) results from the inflammatory, proteolytic and growth factor enriched SECRETOME of many types of senescent cells which leads to tissue repair or tissue and organ damage over time and links SASP to age-related disorders. HN - 2022; use CELLULAR SENESCENCE 2018-2021 BX - Senescent Cell SASP MH - Senotherapeutics UI - D000089322 MN - D27.505.954.803 MS - Chemical agents which induce the removal (by apoptotic or non-apoptotic cell death) or immune-mediated clearance of senescent cells, or the neutralization of the detrimental effects of the SENESCENCE-ASSOCIATED SECRETORY PHENOTYPE. HN - 2022 BX - Geroprotectors BX - Seno-Therapeutic Agents BX - Senolytic Agents BX - Senolytics BX - Senomorphic Agents BX - Senomorphics BX - Senoptosis Inducers BX - Senoptotic Agents BX - Senoptotics BX - Senostatic Agents BX - Senostatics BX - Senotherapeutic Agents MH - Sentiment Analysis UI - D000090042 MN - G17.35.250.750 MN - L1.224.50.375.815 MN - L1.313.500.750.280.199.750 MN - L1.470.625.750 MS - A data mining technique in which subjective information such as sentiments, OPINIONS, and attitudes are extracted and analyzed from data. HN - 2022 BX - Opinion Mining BX - Sentiment Classification MH - Serial Infection Interval UI - D000088822 MN - N6.850.490.844 MS - The interval of time between the onset of symptoms in the primary and secondary case. The serial interval is one of the significant epidemiological measures that determine the spread of infectious disease. HN - 2022 MH - Serine-Threonine Kinase 3 UI - D000090742 MN - D8.811.913.696.620.682.700.897 MN - D12.776.476.563.897 MS - An intracellular-signaling kinase that plays a role in regulating APOPTOSIS. HN - 2022 BX - STK3 Protein Serine Threonine Kinase MH - Shelterin Complex UI - D000089804 MN - A11.284.430.106.279.345.190.160.845.500 MN - D5.500.918 MN - D12.776.260.735.625 MN - D12.776.660.235.700.625 MN - D12.776.664.981 MN - G5.360.160.845.500 MS - A TELOMERE cap complex consisting of telomere-specific proteins in association with telomeric DNA such as telomeric dsDNA-sDNA junction. They are involved in the protection of chromosome ends and TELOMERASE regulation and play a role in CELLULAR SENESCENCE and ageing-related pathology. In general it consists of six mostly TELOMERE-BINDING PROTEINS (POT1, RAP1, TIN2, TPP1, TRF1, and TRF2). HN - 2022 BX - CST Complex BX - Ctc1-Stn1-Ten1 Complex BX - POT1-TPP1 Shelterin Complex BX - Telomere Cap Complex BX - Telomere POT1-TPP1 Complex BX - Telomeric Capping Complex BX - Telomeric Stn1-Ten1 Capping Complex BX - Telosome MH - Sleep Quality UI - D000089943 MN - F2.830.855.734.500 MS - Satisfaction with the sleep experience, integrating aspects of sleep initiation, sleep maintenance, sleep quantity, and refreshment upon awakening. HN - 2022 FX - Polysomnography MH - Sluggish Cognitive Tempo UI - D000087346 MN - F3.625.94.650 MS - Defined by a constellation of caregiver-reported symptoms that includes daydreaming, difficulty initiating and sustaining effort, lethargy, and physical underactivity. These symptoms have been observed in both typically developing children and in some children with Attention-Deficit/Hyperactivity Disorder (ADHD), especially those with the predominantly inattentive presentation. (J Abnormal Child Psychology; 46: Jan 2018.127). . HN - 2022 MH - Social Cohesion UI - D000091782 MN - F1.829.401.694.500 MN - N3.55.750.500 MS - Strength of relationships and the sense of belongingness and solidarity among members of a community (https://www.healthypeople.gov/2020/topics-objectives/topic/social-determinants-health/interventions-resources/social-cohesion). HN - 2022 BX - Group Cohesion BX - Group Cohesiveness BX - Group Solidarity MH - Social Deprivation UI - D000091489 MN - I1.880.853.748.877 MS - Limited access to society's resources due to poverty. discrimination, or other disadvantage. Conditions based on seven demographic characteristics collected in the American Community Survey (ACS): often include percent living in poverty, percent with less than 12 years of education, percent of single parent households, percent living in rented housing unit, percent living in overcrowded housing unit, percent of households without a car, and percent of non-employed adults under the age of 65 years.(https://dictionary.apa.org/socialdeprivation). HN - 2022 BX - Social Deprivation Index MH - Social Status UI - D000091743 MN - I1.880.761.500 MS - The relative prestige, authority, and privilege of an individual or group. HN - 2022 BX - Social Stratification MH - Social Structure UI - D000091485 MN - I1.880.761 MS - The complex of relationships and systems that organize and regulate interpersonal phenomena in a group or society. The social structure of a group includes its norms and roles and the status, attraction, and communication relations that link one member to another (see group structure). The social structure of a society includes the complex of relations among its constituent individuals, groups, institutions, customs, and mores. (https://dictionary.apa.org/social‐structure) HN - 2022 MH - Social Vulnerability UI - D000091482 MN - I1.880.853.919 MS - The characteristics of a person or community that affect their capacity to anticipate, confront, repair, and recover from the effects of a natural or human-caused disaster.(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC71 79070/) HN - 2022 FX - Vulnerable Populations MH - Sociodemographic Factors UI - D000091569 MN - I1.880.853.965 MS - Indicators used to describe individuals in terms of age, race/ethnicity, sex, gender, primary language educational attainment, employment status, income, profession, marital status, total number of persons living in the house and living arrangements, and similar factors. HN - 2022 MH - Sound Recordings UI - D000087983 MN - J1.897.280.500.793 MN - L1.178.820.90.793 MN - L1.280.785 MS - The storing of sound signals on various media such as cylinders, analog discs, digital discs, tapes, and wires.[LCSH, 10/27/2020] HN - 2022 BX - Sound Recording MH - Stress Granules UI - D000088162 MN - A11.284.430.214.190.500.780.750 MN - A11.284.430.214.190.875.190.190.384.750 MS - Cytoplasmic granules composed of RIBONUCLEOPROTEINS which form only when stress-activated pathways stall translation initiation. Stress granules and processing bodies both sequester inactive mRNPs. Stress granules clear mRNPs through autophagy and may interact with P-BODIES. HN - 2022 MH - Stromal Vascular Fraction UI - D000090002 MN - A11.329.830.500.500 MN - A11.872.590.500.500 MS - A fraction of ADIPOSE TISSUE prepared to enrich in STEM CELLS with the capacity for multi-lineage differentiation. It is used in various applications for its tissue regeneration and immunomodulation activities. HN - 2022 (2019) BX - Adipose Stromal Vascular Fraction BX - Adipose SVF BX - Autologous Adipose Stromal Vascular Fraction BX - Autologous Adipose SVF MH - Systemic Racism UI - D000091722 MN - F1.145.813.550.500.500 MN - F1.145.813.629.625.500 MN - I1.880.735.820.500.500.500 MS - Processes of racism that are embedded in laws (local, state, and federal), policies, and practices of society and its institutions that provide advantages to racial groups deemed as superior, while differentially oppressing, disadvantaging, or otherwise neglecting racial groups viewed as inferior. Differential access to the goods, services, and opportunities of society by race. Institutionalized racism is normative, sometimes legalized, and often manifests as inherited disadvantage. It is structural, having been codified in our institutions of custom, practice, and law, so there need not be an identifiable perpetrator. (ttps://www.cdc.gov/chronicdisease/programs‐impact/sdoh.htm) HN - 2022 BX - Institutional Racism BX - Institutionalized Racism BX - Structural Racism MH - TEA Domain Transcription Factors UI - D000091262 MN - D12.776.260.733 MN - D12.776.930.882 MS - A family of transcription factors that share a conserved TEA DNA binding domain. HN - 2022 BX - TEA Domain BX - TEAD Transcription Factors MH - Technology Addiction UI - D000088942 MN - F1.145.527.100.120.875 MS - The inability to overcome a desire to have contact with and use technology and electronic devices. HN - 2022 BX - Cell Phone Addicition BX - Mobile Phone Addiction BX - Video Game Addiction MH - Tenrecidae UI - D000091124 MN - B1.50.150.900.649.313.250.875 MS - A placental mammal family in superorder Afrotheria. HN - 2022(2003) BX - Echinops BX - Tenrec BX - Tenrecinae MH - Three Finger Toxins UI - D000087443 MN - D12.776.831.622 MN - D20.888.850.325.600 MN - D23.946.833.850.325.600 MS - A super-family of non-enzymatic proteins found in ELAPIDAE VENOMES. They possess a unique tertiary structure resembling a hand with three fingers and have diverse biological activities due to sequence and structural variations; some are ALPHA-NEUROTOXINS that bind NICOTINIC ACETYLCHOLINE RECEPTORS. HN - 2022 BX - 3FTXs BX - NK-3FTX BX - Three Finger Toxin BX - Three-Finger Toxins BX - Tschuditoxin-l MH - Thromboinflammation UI - D000090882 MN - C14.907.355.830.749 MN - C15.378.100.876 MN - C23.550.470.895 MS - Thrombosis with associated inflammation due to crosstalk between HEMOSTASIS and INNATE IMMUNE RESPONSES modulated by PLATELETS. It is associated with many diseases such as COVID-19; SICKLE CELL ANEMIA; and THROMBOPHLEBITIS. HN - 2022 BX - Immunothrombosis MH - Transcriptional Coactivator with PDZ-Binding Motif Proteins UI - D000091364 MN - D12.644.360.24.469 MN - D12.776.157.57.437 MN - D12.776.476.24.484 MS - A family of signal transducing adaptor proteins that are similar in structure and function to YAP-SIGNALING PROTEINS. They are components of the HIPPO-SIGNALING PATHWAY, and may act as transcriptional co-activators for TEAD TRANSCRIPTION FACTORS. AN - do not confuse with tafazzin/TAZ protein HN - 2022 BX - TAZ-Signaling Proteins BX - Transcriptional Coactivator with PDZ-Binding Motif (TAZ) Proteins BX - Transcriptional Coactivator with PDZ-Binding Motif Protein BX - WW Domain Containing Transcription Regulator 1 BX - WW Domain-Containing Transcription Regulator Protein 1 MH - Translational Science, Biomedical UI - D000090963 MN - H1.158.945 MS - The field of investigation which seeks to understand the scientific and operational principles underlying each step of the translational process to increase the efficiency and effectiveness of translational research in all therapeutic areas. (from Nat Rev Drug Discov 2018 Jul;17(7):455-456) AN - TRANSLATIONAL RESEARCH, BIOMEDICAL is also available HN - 2022 (2012) BX - Translation, Biomedical BX - Translational Science FX - National Center for Advancing Translational Sciences (U.S.) MH - Tripeptidyl-Peptidase 1 UI - D000091346 MN - D8.811.277.656.350.100.877 MN - D8.811.277.656.350.350.843 MN - D8.811.277.656.959.780 MS - Lysosomal Serine proteases that release N-terminal tripeptide from a polypeptide and cleave peptides between hydrophobic residues. An enzyme that in humans encoded by the TPP1 gene. It is involved in the degradation of bone collagen. Mutations in this gene are associated with the CEROID LIPOFUSCINOSIS, NEURONAL, 2; and SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVECEROID LIPOFUSCINOSIS, NEURONAL, 2; AND SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 7. HN - 2022 (1993) BX - CLN2 Protein BX - TPP1 Protein BX - Tripeptidyl Aminopeptidase I BX - Tripeptidyl Peptidase I BX - Tripeptidyl Protease I BX - Tripeptidyl-Peptidase I MH - Trogocytosis UI - D000088383 MN - G4.917 MN - G12.888 MS - Process in which parts of target cell membrane is actively chopped up or gnawed and transferred to monocytes. Although similar to PHAGOCYTOSIS it does not involve engulfing. HN - 2022 MH - Tumor Protein, Translationally-Controlled 1 UI - D000090324 MN - D12.644.360.963 MN - D12.776.476.941 MN - D12.776.624.720 MS - A highly expressed protein in tumor cells, encoded by Tpt1 gene. It's involved in various cellular activities including protein synthesis, calcium-binding, MICROTUBULE stabilization, growth, and cell survival. Also, Tpt1 identified as a direct target gene of P53 tumor suppression. HN - 2022 (1985) BX - Histamine Releasing Factor BX - Histamine Releasing Factor, Lymphocyte-Dependent BX - Histamine-Releasing Factor (IgE-Dependent) BX - Protein P23, Ehrlich Ascites Tumor BX - TPT1 Protein BX - Translationally-Controlled Tumor Protein MH - UDP-Glucuronosyltransferase 1A9 UI - D000090264 MN - D8.811.913.400.450.480.750 MS - A PPAR alpha and PPAR gamma target gene. The enzyme plays an important role in elimination and DETOXIFICATION of drugs, XENOBIOTICS, and metabolizing endogenous compounds, including CATECHOLESTROGENS and FIBRATES. HN - 2022 (2000) BX - UDP-Glucuronosyltransferase, UGT1A9 BX - UGT1A9 Protein BX - Uridine Diphosphate-Glucuronosyltransferase 1A9 MH - Umbilical Cord Clamping UI - D000087526 MN - E4.520.252.980 MS - Method of placing clamps on the UMBILICAL CORD before cutting after birth. HN - 2022 BX - Delayed Cord Clamping BX - Delayed Umbilical Cord Clamping BX - Immediate Cord Clamping BX - Immediate Umbilical Cord Clamping BX - Placental Transfusion BX - Umbilical Cord Milking MH - Unmanned Aerial Devices UI - D000088722 MN - J1.937.285.100.550 MS - Powered, aerial vehicles that do not carry a human operator, use aerodynamic forces to provide vehicle lift, can fly autonomously or be piloted remotely, can be expendable or recoverable, and can carry a lethal or nonlethal payload. (https://apps.dtic.mil/sti/pdfs/ADA467807 pdf accessed 12/27/2020) HN - 2022 BX - Drone Aircraft BX - Drones BX - Unmanned Aerial Vehicles MH - Uremic Toxins UI - D000087527 MN - D23.946.710 MS - Biological solutes retained and accumulated due to kidney impairment that contribute to uremia/chronic kidney disease. HN - 2022 BX - Uremia Toxins BX - Uremic Retention Solutes MH - Urogenital Diseases UI - D000091642 MN - C12 MS - Pathological processes of the URINARY TRACT and the reproductive system (GENITALIA). AN - general or unspecified; MALE UROGENITAL DISEASES and FEMALE UROGENITAL DISEASES are available HN - 2022 BX - Genitourinary Diseases MH - Vaccination Hesitancy UI - D000088823 MN - F1.100.150.750.750.500.500 MN - F1.145.488.887.750.500.500 MN - I1.880.604.473.650.968.500.500 MN - N3.706.437.650.875.500.500 MN - N5.300.150.800.750.500.500 MS - Delay in acceptance of vaccination despite availability. HN - 2022 BX - Vaccination Delay BX - Vaccine Delay BX - Vaccine Hesitancy MH - Vaccine Development UI - D000087506 MN - E5.952 MS - The entire process of introducing a new vaccine for use in VACCINATION including pre-clinical development, testing in CONTROLLED CLINICAL TRIAL, manufacturing, approval/licensing and distribution. HN - 2022 MH - Vaccine Efficacy UI - D000087507 MN - E5.952.500 MS - A measurement of disease risk reduction among vaccinated compared to unvaccinated persons under ideal conditions such as in a clinical trial. Such disease reduction measured under typical field conditions is vaccine effectiveness. In contrast vaccine potency is measured in an assay to ensure proper dosing and storage of vaccines whereas vaccine immunogenicity measures its ability to induce an immune response in a vaccinated individual in observational studies. HN - 2022 BX - Vaccine Effectiveness MH - Vascular Depression UI - D000088323 MN - C10.228.140.300.794 MN - C14.907.253.896 MN - F3.600.300.887 MS - Late-life depression associated with clinical or MRI defined cerebrovascular pathology. HN - 2022 BX - Subcortical Ischemic Depression MH - Vermilingua UI - D000091142 MN - B1.50.150.900.649.313.999.475 MS - A placental mammalian suborder of anteaters. For spiny anteater see TACHYGLOSSIDAE; and for scaly anteaters, PANGOLINS. HN - 2022(1998) BX - Anteaters BX - Cyclopes BX - Myrmecophagidae BX - Tamandua MH - Vestibular System UI - D000091282 MN - A9.923 MS - The VESTIBULAR APPARATUS in the inner ear, the eye, the CENTRAL NERVOUS SYSTEM and various nerves, tracts and nuclei connecting them as they relate to PROPRIOCEPTION and SPATIAL ORIENTATION. Dysfunction in the vestibular system is associated with various diseases (e.g., VESTIBULAR DISEASES; LABYRINTH DISEASES; VESTIBULAR NEURONITIS; BENIGN PAROXYSMAL POSITIONAL VERTIGO; and MOTION SICKNESS). HN - 2022 MH - Video-Assisted Techniques and Procedures UI - D000087882 MN - E5.956 MS - Techniques or procedures performed with visualization via video transmission. HN - 2022 BX - Video Assisted Techniques MH - Viperin Protein UI - D000090123 MN - D12.776.66.500 MS - A highly conserved IFN-inducible protein with a wide range of antiviral activities by binding to the VIRAL N PROTEIN. HN - 2022 BX - Virus Inhibitory Protein Endoplasmic Reticulum-Associated Interferon-Inducible MH - Viral Pseudotyping UI - D000089942 MN - E1.370.225.875.960 MN - E5.200.875.960 MN - E5.393.880 MS - Technique in which endogenous ENVELOPE PROTEINS have been replaced by use of a chimeric vector. For instance a viral vector with SIMIAN IMMUNODEFICIENCY VIRUS can be coated with the VIRAL ENVELOPE PROTEINS from Vesicular stomatitus virus. Use of these types of vectors are useful in developing NEUTRALIZATION TESTS by enabling infection of almost universal set of host cells. HN - 2022 BX - Pseudotyped Viruses BX - Viropexis BX - Virus Pseudotyping MH - Weight Cycling UI - D000091622 MN - C23.888.144.243.926.750 MN - C23.888.144.243.963.750 MN - G7.345.249.314.120.200.926.750 MN - G7.345.249.314.120.200.963.500 MS - Repeated cycles of weight loss followed by weight gain. HN - 2022 FX - Body Weight Maintenance FX - Body-Weight Trajectory MH - Xenotropic and Polytropic Retrovirus Receptor UI - D000089842 MN - D12.776.543.750.695.977 MN - D12.776.543.750.830.925 MS - A cell surface receptor involved in G-protein recruitment and G-protein-coupled signal transduction. The receptor also plays a role in phosphate homeostasis. HN - 2022 (1999) BX - Receptor, Xenotropic Murine Leukemia Virus BX - Receptor, XPR1 BX - X-MLV Receptor BX - Xenotropic Murine Leukemia Virus Receptor BX - Xenotropic Murine Leukemia Virus Receptors BX - XPR1 Protein BX - XPR1 Receptor MH - YAP-Signaling Proteins UI - D000091102 MN - D12.644.360.24.750 MN - D12.776.157.57.750 MN - D12.776.476.24.750 MS - Signal transducing adaptor proteins that were initially identified by their association with YES PROTO-ONCOGENE PROTEIN. They are downstream components of the HIPPO-SIGNALING PATHWAY, and act as transcriptional co-activators for TEAD TRANSCRIPTION FACTORS. HN - 2022 BX - YAP Intracellular Signaling Proteins BX - Yes-Associated Proteins FX - Transcriptional Coactivator with PDZ-Binding Motif Proteins MH - Zn-Alpha-2-Glycoprotein UI - D000090203 MN - D6.472.699.42.875 MN - D9.400.430.984 MN - D12.644.276.24.875 MN - D12.644.548.11.875 MN - D12.776.395.985 MN - D12.776.467.24.875 MN - D23.529.24.875 MS - A soluble protein that stimulates LIPOLYSIS in ADIPOCYTES and causes the extensive fat losses associated with some advanced cancers. HN - 2022 (1977) BX - Alpha2-Seminoglycoprotein BX - Glycoprotein, Zinc-Alpha(2) BX - Zinc-Alpha(2)-Glycoprotein BX - Zn-Alpha(2)-GP