PMID- 6900160 TI - [Medical gymnastics for bronchial asthma and pollinosis patients]. PMID- 6900161 TI - [Asepsis and antisepsis in stomatology]. PMID- 6900162 TI - [Activities in a pediatric audiometry office]. PMID- 6900163 TI - [Laboratory control over the vitamin C contents in prepared dishes]. PMID- 6900164 TI - [Organization of centralized sterilization in a therapeutic institution]. PMID- 6900165 TI - [Deontology in the work of the dermatology office nurse]. PMID- 6900166 TI - [Basic principles of the treatment and prevention of sepsis in newborn and young infants]. PMID- 6900167 TI - [Health bulletins devoted to protecting the health of schoolchildren]. PMID- 6900168 TI - [Organizational experience of health education work]. PMID- 6900169 TI - [Liquid drug shelf life in hospital wards]. PMID- 6900170 TI - [They live and work in Shushinskoye]. PMID- 6900171 TI - The end of life. PMID- 6900173 TI - The health visitor, schools and teaching. PMID- 6900172 TI - Antenatal care; have Dr Ballantyne's aims been achieved? Part I. PMID- 6900175 TI - Marital breakdown in the light of changing sexual attitudes. PMID- 6900174 TI - Death--whose right to choose? PMID- 6900176 TI - Mental problems in the elderly. PMID- 6900177 TI - How accurate is clinical test weighing of the newborn? PMID- 6900178 TI - The changing role of the midwife. PMID- 6900179 TI - Where have all the midwives gone? PMID- 6900180 TI - Legal Rx for nursing practice: accentuate the positive. PMID- 6900181 TI - President's message. MoNA Goal No. 6: facilitate implementation of the statewide plan for nursing and nursing education. PMID- 6900182 TI - From the Executive Director. Recommendations on nursing and nursing education. PMID- 6900184 TI - Some thoughts on research and the nursing profession. PMID- 6900185 TI - Seeing things through. PMID- 6900183 TI - Activation of the alternative pathway of complement by Malassezia ovalis (Pityrosporum ovale). AB - Activation of C3 and factor B in normal human serum by P. ovale was demonstrated using a standard unidirectional immunoelectrophoresis technique. Activation of complement by the alternative (properdin) pathway is a possible mechanism by which P. ovale may mediate an inflammatory response. PMID- 6900186 TI - Care and safety. PMID- 6900187 TI - The hip joint and femur. PMID- 6900188 TI - Dealing with food fads. PMID- 6900189 TI - Nutrition and mental health: food for thought. PMID- 6900190 TI - U.S. health care: cost & methods of financing. PMID- 6900191 TI - Interface between hospital-based nursing practice settings and the community? PMID- 6900192 TI - Nursing centers can promote health for individuals, families and communities. PMID- 6900193 TI - Continuing care: the educator's role. PMID- 6900194 TI - Educational strategies for a community program in preventing alcohol use during pregnancy. PMID- 6900195 TI - Meeting the health care needs of older adults through a community nursing center. PMID- 6900196 TI - The hospice concept integrated with existing community health care. PMID- 6900197 TI - A hospital-based occupational health service can increase outpatient department utilization. PMID- 6900199 TI - Consumers as members of nursing committees. PMID- 6900198 TI - Evaluation of a sexual assault treatment center. PMID- 6900201 TI - Faculty practice: a professional imperative. PMID- 6900200 TI - Implementing a competency-based orientation program. PMID- 6900202 TI - Learning for mastery: individualized testing through computer-managed evaluation. PMID- 6900203 TI - Fluids in balance: introduction. PMID- 6900204 TI - The sea within: fluids in balance. PMID- 6900205 TI - Drugs and fluid balance. PMID- 6900206 TI - Thinking about drinking: fluids in balance. PMID- 6900207 TI - Fluids off balance: over- and under-hydration. PMID- 6900208 TI - pH in the balance: fluids in balance. PMID- 6900209 TI - Potassium deficit and excess. PMID- 6900210 TI - Restoring the balance: acutely ill patients. PMID- 6900211 TI - Patients with gastrointestinal problems: fluids in balance. PMID- 6900212 TI - Patients with renal disease: fluids in balance. PMID- 6900213 TI - Babies and children: fluids in balance. PMID- 6900214 TI - The elderly: fluids in balance. PMID- 6900215 TI - Pictures in nursing: management of intravenous therapy. PMID- 6900217 TI - Aspects of psychiatry. PMID- 6900216 TI - Fluids in balance: types of intravenous fluids used. PMID- 6900218 TI - "Patients first". PMID- 6900219 TI - Community psychiatric nursing--a challenging role. PMID- 6900220 TI - Attitudes to mental illness. PMID- 6900221 TI - Tottenham Mews day hospital--a profile. PMID- 6900222 TI - Psychiatry: total care in Cambridge Ward. PMID- 6900223 TI - Psychiatry: Simmons House: an adolescent unit. PMID- 6900224 TI - NHS organisation and 'patients first'. PMID- 6900225 TI - Dying for a drink. PMID- 6900226 TI - Law: compensation for negligence. PMID- 6900227 TI - Safety: a model code of practice. PMID- 6900228 TI - OH in the health service. PMID- 6900229 TI - Pregnancy in the workplace. PMID- 6900230 TI - Your future - ANA Proposal 85 - no. PMID- 6900231 TI - "Planning": key word for effective continuing education. PMID- 6900232 TI - American Cancer Society's new recommendations about checkups. PMID- 6900233 TI - The occupational health nurse: safety's overlooked resource. PMID- 6900235 TI - Understanding basic serologic tests for syphilis. PMID- 6900234 TI - The occupational health nurse as counselor - learning to listen. PMID- 6900236 TI - The nurse during a strike. PMID- 6900237 TI - Physical assessment for nurses employed in industrial medicine departments. PMID- 6900238 TI - Industrial toxicology: a practical approach. PMID- 6900239 TI - What is career mobility? Part 4. PMID- 6900240 TI - Alcohol education: children of alcoholics. Part II. PMID- 6900241 TI - The code for nurses: a survey of its content, constitutive structure, and usefulness to the nursing profession. PMID- 6900242 TI - Schools report/career mobility among nurses in Oklahoma. PMID- 6900243 TI - Standards for nursing practice. IX. ANA Standard VI: maximizing client/patient health capabilities. PMID- 6900244 TI - Council on practice. Deciding your destiny: entering and moving in the professional job market. PMID- 6900245 TI - Lack of health services characterizes the disadvantaged. PMID- 6900246 TI - Where are all the nurses? PMID- 6900247 TI - A survey of Iowa pediatricians concerning hiring of pediatric nurse practitioners. PMID- 6900248 TI - Helping expectant parents understand the fetal monitor. PMID- 6900249 TI - The pediatric home liaison in a private practice. PMID- 6900250 TI - Infant care instructions-revised. PMID- 6900251 TI - Pediatric management problems (heart murmur). PMID- 6900252 TI - PNP nutritional assessment kit. PMID- 6900253 TI - Inside me: teaching anatomy to children. PMID- 6900254 TI - Self-care nursing plan: helping children to help themselves. PMID- 6900255 TI - [State of the kallikrein-kinin system in children with acute intestinal infections complicated by pneumonia]. PMID- 6900256 TI - Criteria and standards manual for NLN/APHA accreditation of home health agencies and community nursing services. PMID- 6900258 TI - The political challenges for associate degree nursing: issues and direction. PMID- 6900257 TI - The political challenges for associate degree nursing: issues of the present, direction for the future. PMID- 6900259 TI - The political challenges for associate degree nursing: a college president's view. PMID- 6900260 TI - The ongoing process of state planning. PMID- 6900261 TI - The political challenges for associate degree nursing: issues of the present, direction for the future. Summary and future direction. PMID- 6900263 TI - Practical nursing: curricula and competencies. PMID- 6900262 TI - The political challenges for associate degree nursing: issues of the present, direction for the future. Summary and future direction. PMID- 6900264 TI - Characteristics of an educational program in practical nursing. PMID- 6900265 TI - The conceptual framework in practical nursing curricula. PMID- 6900266 TI - On the competencies of practical nursing graduates. PMID- 6900268 TI - Assuring a goal-directed future for nursing. PMID- 6900267 TI - A political initiative. PMID- 6900269 TI - Development and use of power in nursing. PMID- 6900270 TI - Power begins with you! PMID- 6900271 TI - Future encounters in health care. PMID- 6900272 TI - Concepts of care--from here to there. PMID- 6900273 TI - Predictions and options for nursing and health care. PMID- 6900274 TI - To tell you the truth. PMID- 6900275 TI - Perspective on care. PMID- 6900276 TI - The value of pets. PMID- 6900277 TI - Orthopaedics: cast bracing of femoral shaft fractures-1. The method and its history. PMID- 6900279 TI - Community care study: a health visitor's role in family care. PMID- 6900278 TI - Nursing care study: elective maxillofacial surgery. PMID- 6900280 TI - Psychiatry under review--5. Hints on maintaining patient--nurse interaction. PMID- 6900281 TI - Psychiatry: time for a change. PMID- 6900282 TI - Mental handicap: progress through persistence. PMID- 6900284 TI - Primavera ablutio. PMID- 6900283 TI - Health care overseas: health care in Haiti. PMID- 6900285 TI - Systems of life No 65. Systems and signs: the skin - 2. PMID- 6900286 TI - Toilet training the severely retarded: the importance of evaluation. PMID- 6900287 TI - Caring means sharing. PMID- 6900288 TI - Nurse could you care more? PMID- 6900289 TI - Tread softly. PMID- 6900290 TI - The children's ward annexe, Mayday Hospital. PMID- 6900291 TI - Nursing care study: a special care baby. PMID- 6900292 TI - Education. Counselling and helping skills: how can they be learned?--2. PMID- 6900293 TI - Accommodation: staff shortages in London. PMID- 6900294 TI - Accommodation: flats for nurses in an Aberdeen church. PMID- 6900295 TI - Orthopaedics: cast bracing of femoral shaft fractures--4. When to apply the brace. PMID- 6900296 TI - Psychiatry under review--8. The team approach to psychiatric care. PMID- 6900297 TI - I dare you. PMID- 6900298 TI - Could you care more? PMID- 6900299 TI - A uniformly good idea. PMID- 6900300 TI - Obstetrics: assessment of life in utero. PMID- 6900301 TI - Orthopaedics: cast bracing of femoral shaft fractures--5. Social benefits of the cast brace. PMID- 6900302 TI - Psychiatry under review--9. Confidentiality in psychiatric nursing. PMID- 6900303 TI - The uses and limitations of the concept of role for nurse education. PMID- 6900304 TI - How many nurses? PMID- 6900305 TI - RCN Congress preview. PMID- 6900307 TI - RCN Congress preview: 'Speak up speak out.'. PMID- 6900306 TI - The Rcn's CMH: a private person in a public role. Interview by Laurence Dopson. PMID- 6900308 TI - Rcn Congress preview: if you're going to the RRB. PMID- 6900309 TI - A funny sort of Thursday. PMID- 6900310 TI - Nursing care study: a new life at 61. PMID- 6900312 TI - Nutrition: appetite in the terminally ill patient. PMID- 6900311 TI - Community care: the psychiatric group home--2. PMID- 6900313 TI - Side-effects of radiotherapy. PMID- 6900314 TI - Orthopaedics: cast bracing of femoral shaft fractures--6. An evaluation. PMID- 6900315 TI - Psychiatry under review--10. The rights of mental patients. PMID- 6900316 TI - Challenges for nursing. PMID- 6900317 TI - 'Hello - news desk.'. PMID- 6900318 TI - The game of life (and death). PMID- 6900319 TI - Campaign - exercise: on the move. PMID- 6900320 TI - Campaign - exercise: it makes you feel better, but. PMID- 6900321 TI - This sporting life. PMID- 6900322 TI - Obstructive airway diseases in children. 5. Clearing a pathway. PMID- 6900323 TI - Psychology. 3. The whys and the wherefores. PMID- 6900325 TI - Stoma patients: rural recollections. PMID- 6900324 TI - Students' forum - obstetrics and gynecology. PMID- 6900326 TI - Body image: mirror, mirror, why me? PMID- 6900327 TI - He's always by my side! PMID- 6900328 TI - Management - dependency and establishments. Finding the right level. PMID- 6900329 TI - Nursing care study - mental handicap. Kate - slow but sure progress. PMID- 6900331 TI - A valuable member of the team? PMID- 6900330 TI - Before...and after. PMID- 6900333 TI - COHSE 1980: man at the top. Interview by Andrew Brown. PMID- 6900332 TI - Maternity hospital: the one which should go. PMID- 6900334 TI - COHSE 1980: a necessary evil? PMID- 6900335 TI - COHSE 1980: a look at what's to come. PMID- 6900336 TI - Psychology. 4. A sense of perception. PMID- 6900338 TI - Multiple sclerosis. Cause and cure: unknown. PMID- 6900337 TI - Students' forum: the brain. PMID- 6900339 TI - Multiple sclerosis: both sides of the sheets. PMID- 6900340 TI - Multiple sclerosis: prisoner of the chair. PMID- 6900341 TI - Nursing care study. Psychiatric rehabilitation: winning her independence. PMID- 6900342 TI - Pay: time runs out. PMID- 6900343 TI - When institutionalized mental patients can refuse psychotropic medication. PMID- 6900344 TI - Hospital policies: enforcement equals endorsement. PMID- 6900345 TI - Reimbursement for nursing services: issues and trends. PMID- 6900346 TI - Radical faith: the right stuff? PMID- 6900347 TI - Responding to patients' requests for information. PMID- 6900348 TI - Establishing limits to professional autonomy: whose responsibility? PMID- 6900350 TI - Ethical dilemmas. Reporting incompetent colleagues II: "Will I be sued for defamation?". PMID- 6900351 TI - Repetitive responses in squid giant axons and their premature annihilation by additional brief depolarizing currents. AB - The repetitive responses induced in squid giant axons by the application of sustained depolarizing currents under space clamp conditions are described. The relationships between membrane current, and a number of features of the repetitive response of the living axon are compared to computations made for the Hodgkin-Huxley equations. The comparison suggests that these equations adequately predict the form of the repetitive response, even so far as the ability of a brief additional depolarization to cause a premature end to the repetitive response. PMID- 6900352 TI - Sodium appetite and the oestrous cycle in sheep: effect of oestrogen, progesterone and changes in food intake. AB - Previous studies of voluntary sodium intake and electrolyte excretion in sheep suggested that the pattern of intake associated with the oestrous cycle was not a response to alterations in sodium balance. The pattern thus seemed likely to be dictated by changes in either hormonal levels or food intake. These possibilities were examined in experiments with ovariectomized sheep. Physiological doses of oestrogen or progesterone had no effect on sodium preference, whether given in isolation or succession. Depression of food intake by 25% (as at oestrus) did affect preference slightly (though significantly) but in the opposite direction to the change at oestrus. It is concluded that none of these 3 factors is responsible for the varying sodium preference during the oestrous cycle and that direct hypothalamic control of this pattern is an interesting possibility. PMID- 6900353 TI - An analysis of the choleretic effects of infusions of sodium cholate in the guinea-pig. AB - The choleretic effects of infusions of sodium cholate, with and without the simultaneous infusion of taurine was compared with the choleretic effect of infusions of sodium taurocholate at rates ranging from 20--70 nmole/min. g. liver in anaesthetized guinea-pigs. Sodium cholate was secreted in bile mainly conjugated with taurine and with glycine. 10% was secreted unconjugated. Not more than 10% of the total bile salts secreted may have undergone reduction at C-3. The increase in bile flow with sodium cholate was generally greater than that with sodium taurocholate. The additional flow could not be correlated with the presence of glycocholate or free cholate in bile, and may be due to an action of cholate on biliary secretory mechanisms before the bile salt is secreted into the canaliculi. PMID- 6900354 TI - The effect of exogenous adenosine triphosphate on potassium movements in HeLa cells. AB - The effect of exogenous adenosine triphosphate (ATP) on the potassium movements of cultured HeLa cells has been studied. The results obtained were consistent with the hypothesis that, in these cells, externally applied ATP activates a tightly coupled potassium-potassium (K-K) exchange mechanism. The response to ATP was characterized by a transient, 20-fold increase in both the potassium influx and potassium efflux. The tight coupling of the K-K exchange mechanism was confirmed by the results of several different types of experiment, all of which demonstrated the consistent matching of the ATP-stimulated fluxes. Two different strains of HeLa cells gave quantitatively different responses under similar experimental conditions. The reason for this difference was investigated and evidence was obtained which was consistent with the view that the membrane potential also influenced the HeLa cell K-K exchange mechanism. PMID- 6900355 TI - A new technique for maintaining and monitoring conscious, stress-free rabbits in a steady state: its use in the determination of glucose kinetics. AB - 1. A new technique is described for maintaining and monitoring conscious rabbits in a steady state. Solutions were infused and blood samples were withdrawn without major surgery and without causing stress. Cannulation, for infusion and blood sampling, was via the ear veins and arteries. 2. The validity of the technique is discussed with special reference to: the amount of blood removed from the animal; the use of a plasma substitute solution; the use of heparin; and assessing whether the animal was in a steady-state with respect to glucose. 3. The technique was used to determine glucose kinetics in the fasted rabbit after an injection of [2-(3)H]glucose with subsequent blood sampling over 2 h. A two compartment model was used to calculate certain physiological values, the two principal ones being the glucose uptake rate (3.30 +/- 0.24 (13) mg.kg-1.min-1) and the initial volume of distribution (74.8 +/- 7.8 (13) ml.kg-1). 4. The accuracy and precision of the results obtained from this study are discussed and shown to be more reliable than other published values. PMID- 6900356 TI - Radiographic heart volume, stroke volume and exercise cardiac frequency: relationship to body composition and other factors in healthy adult males. AB - Amongst 288 healthy male workers in heavy industry the radiographic heart volume was related to the fat-free mass and the percentage body fat which between them explained 27% of the variance. Exercise was performed on a treadmill using a belt speed of 80 m.min-1 (3 mph) and an incline which was increased progressively to 14% when the oxygen uptake was on average 61% of the maximum for these subjects. The exercise cardiac output was related to the uptake of oxygen, the fat-free mass and the ambient temperature; these factors accounted for 52% of the variance. The exercise stroke volume was related to the heart volume, the fat free mass, the thigh muscle width, the ambient temperature, the Harvard Pack Index and other measurements which between them accounted for 42% of the variance. The exercise cardiac frequency was correlated negatively with the heart volume, the fat-free mass, the age and the Harvard Pack Index. The variates between them described 41% of the variance. The findings provide reference values for heart volume, stroke and exercise cardiac frequency in similar subjects. PMID- 6900357 TI - Sex q & a: Frank answers to your most delicate patient-counseling questions. PMID- 6900359 TI - Coping: why you 'just can't take it anymore!'. PMID- 6900358 TI - Honing your respiratory assessment technique. PMID- 6900360 TI - Tiny lifesaver: the intracaval filter: new nursing challenge. PMID- 6900362 TI - A candid look at MD incomes. PMID- 6900361 TI - What to watch for with salicylates. PMID- 6900363 TI - Dysrhythmia of the month club. PMID- 6900364 TI - Antiepileptic drug update: from emergency to maintenance. PMID- 6900365 TI - Why COPD can end in heart failure ...and what you can do about it. PMID- 6900366 TI - Why your cancer patient won't eat. PMID- 6900367 TI - Legally speaking: leave detective work to the cops. PMID- 6900369 TI - The shortage: good jobs are going begging these days, so why not be choosy? PMID- 6900368 TI - Sound off! Must we downgrade nurses to upgrade nursing? PMID- 6900370 TI - Dysrhythmia of the month club. PMID- 6900371 TI - Toward complication-free recoveries for your surgical patients. PMID- 6900372 TI - Platelets: a short course: how to safely collect and transfuse them. PMID- 6900373 TI - Emotional commitment how much dare you care? PMID- 6900374 TI - New hope for 'hands-on' nurses: clinical promotions. PMID- 6900375 TI - Cancer chemotherapy; those dreaded side effects and what to do about them. PMID- 6900377 TI - Sound off! Porn nurses: make them clean up their act. PMID- 6900376 TI - Legally speaking; unnecessary stillbirth. PMID- 6900378 TI - Sound off! Nurses who care. PMID- 6900379 TI - Sound off! Nurses who don't care. PMID- 6900380 TI - Nurses 'n Labour: union counselling. PMID- 6900382 TI - Open letter to the Board of Directors. PMID- 6900381 TI - The life of an emergency nurse. PMID- 6900383 TI - [Choice of a contraceptive method]. PMID- 6900384 TI - [Sociodemographic and psychological aspects of contraceptive practice]. PMID- 6900385 TI - [Voluntary interruption of pregnancy]. PMID- 6900386 TI - [Information in matters of contraception: a role for the nurse]. PMID- 6900387 TI - [Nurse's role in voluntary pregnancy interruption and contraception]. PMID- 6900388 TI - [Contraception]. PMID- 6900389 TI - [Voluntary interruption of pregnancy: admission in the facilities concerned under the application of the legislation]. PMID- 6900390 TI - [Education in family planning in schools of nursing in various European countries]. PMID- 6900392 TI - [Care of the patient in coma]. PMID- 6900391 TI - [Organization of nursing care in the various countries of the E.E.C]. PMID- 6900393 TI - [Oral contraception]. PMID- 6900394 TI - [Radiotherapy and cancer]. PMID- 6900396 TI - [Oncology. Unending research, important advances already realized]. PMID- 6900395 TI - [Current immunotherapy treatment]. PMID- 6900397 TI - [Antineoplastic chemotherapy]. PMID- 6900398 TI - [Treatment of a neoplasm using specific chemotherapy]. PMID- 6900399 TI - [Malignant melanoma of Mr. X]. PMID- 6900400 TI - [Results and hopes of research in cancer]. PMID- 6900401 TI - [Goals and functions of comparative tests in oncology]. PMID- 6900402 TI - [Report of a patient care team with a cancer patient in the dying stage. Sensitivity of the team, information of and participation by the family]. PMID- 6900403 TI - [Nursing care: a quality Francophone encounter]. PMID- 6900404 TI - System analysis can solve nursing management problems. PMID- 6900405 TI - Values: part I. PMID- 6900406 TI - Probing the change process. PMID- 6900407 TI - What is the professional nurse (really?) PMID- 6900408 TI - Why participative management in the modern hospital? PMID- 6900409 TI - Making job satisfaction a reality for nurses. PMID- 6900410 TI - Law for the nurse supervisor. Nurse's charting--part I. PMID- 6900411 TI - Perpectives in nursing. Nurturing the profession. PMID- 6900412 TI - The art & science of supervision. The adversaries. PMID- 6900413 TI - Nurses are human, too ... or what's in a title? PMID- 6900415 TI - A time apart. PMID- 6900414 TI - Nursing Practice Act revisions and upcoming Sunset Review. PMID- 6900416 TI - Idealism and the professional. PMID- 6900417 TI - Know your generics: the anticonvulsant drugs. PMID- 6900418 TI - American nurse-tourist: lesson from the Philippines. PMID- 6900419 TI - Nursing--its diversified roles: spotlight on midwives. PMID- 6900421 TI - "Who, me? Write?". PMID- 6900420 TI - Legislation. PMID- 6900422 TI - Career trends: nursing manpower--time for a policy shift? PMID- 6900423 TI - Short procedure unit. PMID- 6900424 TI - Professional codes and personal values: some implications of incongruence. PMID- 6900425 TI - AORN interview: Barbara J Gruendemann and Barbara Stanewick (by Kenton T. Finch). PMID- 6900426 TI - Test your knowledge: nasogastric suction. PMID- 6900427 TI - [Fluorescence spectroscopy studies of interactions of leucyl-tRNA-synthetase with substrates]. AB - Interactions of leucyl-tRNA synthetase with substrates were studied by fluorescence spectroscopy. The formation of enzyme-substrate complexes results in the quenching of protein fluorescence. The equilibrium binding constants were determined for L-leucine, ATP, tRNAleu and leucyladenylate. It is shown that the interaction of the enzyme with ATP or tRNAleu leads to 10-30-fold increase in the binding constants for subsequent interaction of the second substrate. The data obtained indicate to the cooperative interaction between ATP and tRNA binding sites. PMID- 6900428 TI - Marketing veterinary medicine: by what means? PMID- 6900430 TI - Canine socialization--Part 2. PMID- 6900429 TI - The basic clinical pathology laboratory--3: evaluation of the erythrocytes: hematocrit and hemoglobin determinations. PMID- 6900431 TI - Drug-induced hepatitis in a dog: a case report. PMID- 6900432 TI - Ehrlichiosis in an Irish Setter in Mississippi: a case report. PMID- 6900433 TI - Anomaly of the reproductive organs in an infertile cat. PMID- 6900434 TI - Use of a copper intracystic device to treat urinary obstruction in male cats. PMID- 6900436 TI - Granulosa cell tumor in a Golden Retriever. PMID- 6900435 TI - Reconstructive surgery after use of a urethral prosthesis in a castrated cat. PMID- 6900437 TI - A modified muscle-spreading incision for laparorumenotomy in the bovine species. PMID- 6900438 TI - Nitrate poisoning in Oklahoma cattle. PMID- 6900439 TI - Infectious bovine abortion: a practitioner's approach to diagnosis. PMID- 6900440 TI - Practical pharmacokinetic aspects of mastitis therapy--2: practical & therapeutic applications. PMID- 6900441 TI - Design of an equine mobile surgery table. PMID- 6900442 TI - Diagnosis and treatment of infertility in the mare. PMID- 6900443 TI - Cryosurgical removal of an intranasal granuloma from an African Gray parrot. PMID- 6900444 TI - Xanthoma in a gopher snake. PMID- 6900445 TI - Use of ketamine-diazepam and ketamine-xylazine combinations in guinea pigs. PMID- 6900446 TI - Tax-wise: tidbits of tax savvy that could save you money. PMID- 6900447 TI - Changing perspectives on attitudes toward animals and client relations in veterinary practice--1. PMID- 6900448 TI - Evaluation of the erythrocytes (total erythrocyte count, erythrocyte indices and sedimentation rate). PMID- 6900449 TI - Referring the client to an obedience instructor. PMID- 6900450 TI - Brucella canis infection in a kennel. PMID- 6900451 TI - A fistulous tract induced by a foreign body in a dog. PMID- 6900452 TI - Field evaluation of anti-flea collars for initial and residual efficacy on dogs. PMID- 6900453 TI - Pulmonary trematodiasis in a cat: a case report. PMID- 6900454 TI - Improvements in a technique of cosmetic repair of canine ears with stainless steel wire implants. PMID- 6900455 TI - Canine coccidioidomycosis: a case report. PMID- 6900456 TI - The significance of depression in caged birds: a clinical note. PMID- 6900457 TI - Nutrition and its subsequent effects on diseases. PMID- 6900458 TI - Practical pharmacokinetic aspects of mastitis therapy--3: intramammary treatment. PMID- 6900459 TI - Percent creatinine clearance ratios. PMID- 6900460 TI - Hock lameness associated with degeneration of the talocalcaneal articulation: report of two cases in horses. PMID- 6900461 TI - Concomitant use of oxfendazole & trichlorfon as an equine anthelmintic in mares. PMID- 6900462 TI - A clinically suspected case of disseminated intravascular coagulopathy in a female chimpanzee (a case report). PMID- 6900463 TI - Manual restraint of the ferret. PMID- 6900465 TI - Tax-wise: tidbits of tax savvy that could save you money. PMID- 6900464 TI - How staff meetings build a harmonious practice. Part 2. PMID- 6900466 TI - School nurse bill passage took work. PMID- 6900467 TI - Respiratory distress syndrome. Critical care analysis: Matthew, a neonate with RDS. PMID- 6900469 TI - A.A.R.N. calls for changes in health care system. PMID- 6900468 TI - Health education and alternatives to drugs. PMID- 6900470 TI - Alcohol and your unborn baby. PMID- 6900471 TI - Message from nursing consultant--practice. PMID- 6900472 TI - Urine kallikrein and kinin excretions in dogs during renal artery constriction and release. PMID- 6900473 TI - A conceptual model of community health nursing. PMID- 6900474 TI - A statement on the scope of maternal and child health nursing practice. PMID- 6900476 TI - The primary health care nurse practitioner. PMID- 6900475 TI - Funding nursing education. PMID- 6900477 TI - Neurological aspects of rehabilitation Part 1: Brain injury. PMID- 6900478 TI - Patient classification for nurse staffing in rehabilitation. PMID- 6900479 TI - Faculty clinical practice: the strategy for reconciliation. PMID- 6900480 TI - School nurse helps develop new program. PMID- 6900482 TI - Nursing manpower study for the State of Arizona. PMID- 6900481 TI - Can nursing and motherhood be compatible? PMID- 6900483 TI - Continuing education: who pays? PMID- 6900484 TI - A special African day for an ordinary Australian nurse. PMID- 6900485 TI - Drugs in current use: calcitriol. PMID- 6900486 TI - Our attitude of mind in the psychological treatment of cancer. PMID- 6900488 TI - Community nursing in developing countries. PMID- 6900487 TI - From haemorrhage to harmony in the labour ward. PMID- 6900489 TI - Development of a learning tool at WASON. PMID- 6900490 TI - Primary care our way ahead. PMID- 6900491 TI - Some factors affecting quality care: a nursing viewpoint. PMID- 6900492 TI - Undergraduate student placements in community health centres: useful to whom? PMID- 6900494 TI - Some thoughts on a duty of care. PMID- 6900493 TI - Quality assurance in Australia. PMID- 6900495 TI - Technology - a means to the end? PMID- 6900496 TI - Essay competition winner--Nursing Expo '79 week. Come the raw prawn. PMID- 6900497 TI - I remember the rose: a study in communication. PMID- 6900499 TI - Auxiliary nursing in Tasmania: a survey of the role, function and status of the Tasmanian auxiliary nurse. PMID- 6900498 TI - Needs of the elderly. PMID- 6900500 TI - Nursing education beyond 1985. PMID- 6900501 TI - The middlescent woman--and the menopausal syndrome. PMID- 6900502 TI - Family planning in urban Aboriginal and Islander communities. PMID- 6900503 TI - Supervised toothbrush instruction for pre-school children. PMID- 6900504 TI - The smoking patterns and attitudes of student nurses and student teachers. PMID- 6900505 TI - The nursing profession and medical students. PMID- 6900506 TI - Negotiating the contract of employment. PMID- 6900507 TI - Security of employment. PMID- 6900508 TI - Proton nuclear magnetic resonance study on the roles of histidine residues in the binding of polypeptide chain elongation factor Tu from Thermus thermophilus with aminoacyl transfer ribonucleic acid and guanine nucleotides. AB - Proton nuclear magnetic resonance (1H NMR) spectra were measured of the polypeptide chain elongation factor Tu (EF-Tu) from an extreme thermophile, Thermus thermophilus HB8 [Nakano, A., Miyazawa, T., Nakamura, S., & Kaziro, Y. (1979) Arch. Biochem. Biophys. 196, 233-238], in order to elucidate the environment around functionally important histidine residues. In the present study, the behavior of five histidine C2 proton signals was studied in more detail. A hydrogen-deuterium exchange experiment was carried out on the histidine C2 protons of free EF-Tu, and the previous assignments of C2 proton signals were revised in part. An analysis of the 1H NMR spectra of EF-Tu photooxidized under various conditions indicates that a histidine residue is located in the aminoacyl tRNA binding site and is probably essential for the binding with aminoacyl-tRNA. A solvent-accessible histidine residue is found to lie near the aminoacyl-tRNA binding site. Furthermore, the effect of paramagnetic hexacyanochromate(III) ion on the 1H NMR spectra of free EF-Tu suggests that another histidine residue lies near the guanine nucleotide binding site. PMID- 6900510 TI - Cults - another opinion. PMID- 6900509 TI - Human pancreatic proelastase 2. Sequence of the activation peptide. AB - The N-terminal sixteen residues of the amino acid sequence of reduced and alkylated human pancreatic proelastase 2 have been established, and N-terminal amino acid residue has been shown to be carboxymethylcysteine. A peptide containing an amino acid sequence corresponding to the first twelve residues of proelastase 2 was isolated following activation of proelastase 2 with trypsin, performic acid oxidation, and gel filtration. This peptide was not released prior to performic acid oxidation, suggesting that it remains attached to the major peptide chain via a disulfide bond containing the N-terminal half-cysteine in a manner similar to that found for chymotrypsinogens. However, the amino acid sequence of the activation peptide is not strongly homologous to either porcine chymotrypsinogen A or porcine proelastase 1. PMID- 6900511 TI - The ethics of behavior control: the nurse as a double agent. PMID- 6900512 TI - To the Moon and back - an interview with an ex-Moonie. PMID- 6900513 TI - The cancer unit. PMID- 6900514 TI - Experience of time during the crisis of cancer. PMID- 6900515 TI - A common sense approach to caring for children with cancer:the community health nurse. PMID- 6900517 TI - ACS recommendations. PMID- 6900516 TI - Multiple myeloma. PMID- 6900518 TI - Programmed instruction: cancer care. Immunology; immunotherapy. I. PMID- 6900519 TI - Innovation in education. PMID- 6900520 TI - Arteriovenous malformations of the brain. PMID- 6900521 TI - Elastase-like enzymes in skin fibroblasts and rat aorta smooth muscle cells. PMID- 6900522 TI - [Nurse patient communication]. PMID- 6900523 TI - [The tertiary educational function of the nurse]. PMID- 6900524 TI - Helping parents cope with a cleft lip and palate. PMID- 6900525 TI - [The autistic child's inadequate encounter with other persons]. PMID- 6900527 TI - Care and caring. PMID- 6900526 TI - Continual assessment of student nurses. PMID- 6900528 TI - [Personality characteristics in essential hypertension of colored women]. PMID- 6900529 TI - Caring for out patients--fact or legend. PMID- 6900530 TI - [The abused child]. PMID- 6900531 TI - The effects of transcultural influences in community psychiatry as they affect the community nurse. PMID- 6900532 TI - The management of high risk labours by midwives with advanced training. PMID- 6900533 TI - Voluntary nursing in Natal. PMID- 6900534 TI - More about insecticides. PMID- 6900535 TI - Adoption procedures. PMID- 6900536 TI - [An educational process to lead the student to understanding of the patient - to acknowledge the natural "self" and utilize it in nursing]. PMID- 6900537 TI - [On "understanding the patient" - a study through a verbal record]. PMID- 6900538 TI - [An impression and a thought on the article, "an educational process to lead the student to understanding of the patient"]. PMID- 6900539 TI - [Nursing scene with a cancer patient - a study on a gap between the patient and nurse]. PMID- 6900540 TI - [On the formats of nursing and education - in a regular nursing course (2)]. PMID- 6900541 TI - [Interactions with a disease - wholesome life of a patient. (4). Disease and work]. PMID- 6900542 TI - Hypothermia in the critically ill. PMID- 6900543 TI - Dehydration. PMID- 6900544 TI - Health care of the American Indian patient. PMID- 6900545 TI - Pharmacology update! Drug essentials for the critical care team. Sodium nitroprusside - Nipride - no. 8. PMID- 6900546 TI - Emergency care update! Triaging pediatric emergencies. PMID- 6900547 TI - Patient education update! Beginning to teach. PMID- 6900548 TI - Insect venom products. PMID- 6900549 TI - The critical heatstroke patient. PMID- 6900550 TI - Aspirin update! PMID- 6900552 TI - Patient education update! Meeting individual differences as you begin to teach. PMID- 6900551 TI - Update - psychosocial aspects of critical care. PMID- 6900553 TI - Renal failure. PMID- 6900554 TI - Guidelines for management of acute phencyclidine intoxication. PMID- 6900555 TI - Respiratory care update! Pulmonary emboli - Part II. PMID- 6900556 TI - Selected list of normal values: normal urine values. Part II. PMID- 6900557 TI - Emergency care update! near drowning. PMID- 6900558 TI - Hypertension update. PMID- 6900559 TI - Snakebite update. PMID- 6900560 TI - Non cardiogenic pulmonary edema. Respiratory care update! PMID- 6900561 TI - Psychological reactions to myocardial infarction. Part I. Psychosocial update! PMID- 6900562 TI - The pathophysiology of heatstroke. PMID- 6900563 TI - Congenital deficiency in plasma kallikrein and kininogens in the brown Norway rat. AB - The kallikrein-kininogens-kinins system has been investigated in the brown Norway rat. In this breed the stores of kininogens in the plasma are reduced and the plasma kallikrein-like activity appears to be absent both in vivo and in vitro. PMID- 6900564 TI - Met-tRNA-Met-f is located in close proximity to the beta subunit of eIF-2 in the eukaryotic initiation complex, eIF-2 . Met-tRNA-Met-f . GDPCP. PMID- 6900565 TI - Vanadate inhibits mevalonate synthesis and activates NADH oxidation in microsomes. PMID- 6900566 TI - [Tick-borne viral hemorrhagic fevers]. PMID- 6900567 TI - [Methods and agents for focal disinfection]. PMID- 6900568 TI - [Iron-deficiency anemia]. PMID- 6900569 TI - [Adrenal diseases in children]. PMID- 6900570 TI - [Actions of medical first aid brigades in criminal cases, suicides and suicide attempts]. PMID- 6900571 TI - [Antitubercular preparations]. PMID- 6900572 TI - [Action of tobacco poisons on the digestive organs (material for talks)]. PMID- 6900573 TI - [Work experience of a health center in a machine-building plant]. PMID- 6900574 TI - [Corticotherapy in the prevention of respiratory distress syndrome in premature infants]. PMID- 6900575 TI - [Guidance of women following mastectomy]. PMID- 6900576 TI - [Social service in a general hospital]. PMID- 6900577 TI - [Being a nurse today and tomorrow?]. PMID- 6900578 TI - [Special relational problems with diabetes patients]. PMID- 6900580 TI - Excellence in nursing. PMID- 6900579 TI - Inhibitory properties of bull seminal plasma proteinase inhibitors. PMID- 6900581 TI - Leadership in practice. PMID- 6900582 TI - Nurse managed clinics: an approach to graduate community health nursing education. PMID- 6900583 TI - The quest for quality: an exploration of attempts to define and measure quality nursing care. PMID- 6900584 TI - Clinical evaluation of students of nursing: a step toward quality nursing practice. PMID- 6900585 TI - Prevalence of resistance plasmids and the intricacies of ampicillin resistance transfer in S. newport strains isolated in Delhi (1975-77). PMID- 6900586 TI - [Dietary regime in renal insufficiency]. PMID- 6900587 TI - [Thermometer-induced ulceration of the rectum]. PMID- 6900588 TI - [Pathogenesis, etiology and medical treatment of biliary lithiasis]. PMID- 6900589 TI - [Dermatology]. PMID- 6900590 TI - [Inoculation viral hepatitis]. PMID- 6900591 TI - [Yellow fever]. PMID- 6900592 TI - [Cholera]. PMID- 6900593 TI - [World Health Organization. Sex education]. PMID- 6900594 TI - [Social Security in the framework of the European Economic Community]. PMID- 6900595 TI - [Suicide in the aged]. PMID- 6900597 TI - [Accompanying the dying: is it possible?]. PMID- 6900596 TI - [Theory of ego development and its significance for the profession]. PMID- 6900598 TI - [Becoming familiar with death]. PMID- 6900599 TI - [Legal aspects. Mental deficiency and sterilization: the case of Eve]. PMID- 6900600 TI - Nursing and child health in Brazil. PMID- 6900601 TI - An expanded role for nurses as paediatric health care providers in Ghana. PMID- 6900602 TI - Nursing: thoughts on nursing service and identification of the service offered. PMID- 6900603 TI - Care for the worried well. PMID- 6900604 TI - Primary care utilization and psychological distress: a new model for health care delivery. PMID- 6900605 TI - An experiential learning laboratory: a new dimension in teaching mental health skills. PMID- 6900606 TI - A comparison of attitudes toward menopause held by women during the three phases of the climacterium. PMID- 6900607 TI - Strategies for parenting during the early stages of a child's life. PMID- 6900608 TI - Constraint on school nurse-teachers' performance of preventive mental health activities in elementary schools. PMID- 6900609 TI - The impact of group and individual therapy on socialization of residents in an institutional setting. PMID- 6900610 TI - Sex education for adults: use of sexual knowledge inventory. PMID- 6900611 TI - A study of influence of role modeling on students' attitude formation during their psychiatric rotation. PMID- 6900612 TI - Divided loyalties. PMID- 6900613 TI - A project on home accidents. PMID- 6900614 TI - The health visitor and the law: The health visitor in court--2. PMID- 6900615 TI - Know your organizations: the Stillbirth and Perinatal Death Associations. PMID- 6900616 TI - Thoughts of a health visitor housewife. PMID- 6900617 TI - WHO infant and young child feeding. PMID- 6900618 TI - Clinical ecology. PMID- 6900619 TI - Evaluation of growth charts. PMID- 6900620 TI - Genetic counseling of families with endocrine disorders. PMID- 6900621 TI - Nursing care of children with fluid and electrolyte disorders. PMID- 6900622 TI - Is the baby just spitting? Consideration of the gastroesophageal reflux. PMID- 6900623 TI - Clinical aspects of rheumatic fever: an update. PMID- 6900624 TI - Nursing implications in the early recognition of necrotizing enterocolitis. PMID- 6900625 TI - Emergency room care of the poisoned child. PMID- 6900626 TI - Drug interactions: mechanisms and management. PMID- 6900627 TI - Deliberate self-poisoning in children and adolescents. PMID- 6900628 TI - Bu-2313, a new antibiotic complex active against anaerobes. I. Production, isolation and properties of Bu-2313 A and B. AB - An unidentified oligosporic actinomycete strain, No. E864-61, produced two new antibiotics, Bu-2313 A (C27H35NO9) and Bu-2313 B (C26H33NO9). Bu-2313 A and B each exhibited a broad antibiotic spectrum against Gram-positive and Gram negative anaerobic bacteria, and showed in vivo activity against experimental infections produced by B. fragilis and C. perfringens. Bu-2313 also inhibited some aerobic bacteria such as streptococci. Bu-2313 B was approximately two-fold more active than Bu-2313 A. PMID- 6900629 TI - Bu-2313, a new antibiotic complex active against anaerobes. II. Structure determination of Bu-2313 A and B. AB - The structures of Bu-2313 A and B have been determined. They are dienoyltetramic acid-containing antibiotics structurally related to streptolydigin and tirandamycin. PMID- 6900630 TI - Bu-2313, a new antibiotic complex active against anaerobes. III. Semi-synthesis of Bu-2313 A and B, and their analogs. AB - Analogs of Bu-2313 A and B were prepared by C-acylation of tetramic acid derivatives with the dienoic acid moiety obtained by periodate oxidation of Bu 2313 A or B. The C-acylation proceeded in the presence of a strong base such as potassium t-butoxide, sodium hydride or lithium hydride, whereas the use of triethylamine afforded O-acylated products. The semi-synthetic Bu-2313 analogs exhibited antibacterial spectra similar to the parent antibiotic but none exceeded Bu-2313 B in activity. PMID- 6900631 TI - One-step purification of human leukocyte elastase by biospecific affinity chromatography at subzero temperatures. PMID- 6900633 TI - Nursing managers need education too. PMID- 6900632 TI - Acute phase proteins, C9, factor B, and lysozyme in recurrent oral ulceration and Behcet's syndrome. AB - The concentrations and sequential changes of some acute phase proteins, factor B, and lysozyme have been assayed in recurrent oral ulceration and Behcet's syndrome. C9 was elevated in both groups of patients and was the sensitive index of disease activity; however, it failed to discriminate between the three types of recurrent oral ulcers and four types of Behcet's syndrome. The level of alpha 1 acid glycoprotein and lysozyme were significantly increased predominantly in the ocular type, whereas factor B was significantly increased especially in the neurological type of Behcet's syndrome. It is suggested that the changes in the concentrations of some plasma proteins may help our understanding of tissue involvement in Behcet's syndrome, as well as in the selection of therapeutic agents in this disease. PMID- 6900634 TI - Preserving the essence of nursing in a technological age. PMID- 6900635 TI - Philosophy and nursing. AB - It is claimed that philosophy has a distinctive contribution to make to the education of nurses and their teachers, as well as to the development of nursing theory and research. After a brief characterization of philosophy and philosophy of education, stressing its relationship with thinking processes, and the development of personal values, the above claim is supported in the body of the article by discussion of four central concerns in nursing. First the concept of caring where cognitive, moral and attitudinal aspects are examined and secondly, the importance of gaining a moral and political consciousness of assumptions underlying a nurse's work. Thirdly, a discussion of some ethical and other implications in adopting a systems approach to the nursing process. Finally an anlysis of nursing theory and research which draws attention to the value of non empirical work, and reiterates criticisms of the objectives approach as a research tool. PMID- 6900636 TI - Care of the unconscious patient: a complementary perspective. AB - The literature associated with the care of the unconscious patient tends to concentrate on aspects of care relevant to the maintenance of the patient's equilibrium within a medical or surgical context (Atkinson 1970, Roper 1973, Ayres 1974, Burrell & Burrell 1977, Rhodes 1977). The importance of maintaining such an equilibrium is beyond dispute, but the difficulty of understanding what unconsciousness is becomes a contributory factor towards inhibiting the nurse from extending the same totality of care she would offer the conscious patient, to one who is unconscious. The writers draw parallels between features of the world of 'booming, buzzing confusion' often postulated for the neonate, and those of the unconscious patient. They claim that despite perceptual and other similarities, the framework of care instituted for the unconscious patient lacks the social dimension normally expected to be available to the infant. Care of the unconscious patient suffers from fragmentation because of its emphasis on the physical. PMID- 6900637 TI - A model for establishment of educational programmes in developing countries: the nursing paradoxes in Kuwait. AB - While American nursing attempts to deal with the multitude of dilemmas that have been plaguing it for decades, many developing countries look to the USA for a nursing model to emulate, and then become lost in this confusion of its nursing profession. However, these countries continue to reach out and seek consultants with educational and practical experience in nursing in the USA, as well as in other developed countries. A paradigm is proposed for use by educators and consultants to help delineate the major issues a developing country has to confront in establishing a stable nursing service. This paradigm is explicated by applying it to the situation in Kuwait, a Fourth World country with many social paradoxes (e.g., rich in economic resources but poor in human resources). Four major paradoxes in nursing are identified by using the proposed paradigm. They are: 1 educational needs vs. educational reality; 2 locals vs. cosmopolitans; 3 role congruency vs. role incongruency; and finally 4 medical vs. nursing conceptual models. Although these paradoxes became manifest through work done by the author in Kuwait, any international health care professional will quickly realize that the prardoxes are not unique to Kuwait but have parallels in many other countries which are at different stages of development. PMID- 6900638 TI - Towards rational midwifery service planning. AB - Although the work reported here began at health district level, even a casual perusal of published statistics reveals a quite bizarre situation when viewed from a manpower planning perspective. The quite considerable effort involved in producing state-certified midwives seems, on the surface at least, to be excessive given the number gainfully employed in that profession. The national situation with respect to trends in the birth rate is examined and a somewhat surprising seasonal effect identified. This material is then used to estimate the likely situation to be encountered at local level and in particular the effect at different levels of bed provision. In an attempt to translate these estimated births into workload figures recourse was made to regression analysis. Data from 417 maternity units relating both to outputs and inputs were secured, but the subsequent analysis proved abortive due to the high correlation which exists between the variables. Estimates were therefore derived from the work of other authors. PMID- 6900639 TI - Whooping cough vaccination: some reasons for non-completion. AB - The decline in the number of children nationally being vaccinated against pertussis has caused anxiety and concern, both for parents and for professional workers. Publicity by the media and professional press has added to the confusion, and has been largely held responsible for the present situation. A survey was undertaken to analyse the factors which may have been responsible for the reduction in the number of children coming forward for pertussis vaccination in Leicestershire. These factors included social class, the position of the child within the family, and the reasons given by families for omission of the vaccine. Observations on the computerized record of immunization and vaccination, and the family's own record of the dates of immunization were made. The results of the survey present a more complicated picture than expected, with the consequence that solutions are difficult to find. PMID- 6900640 TI - Keeping up with 'Mrs Chase': an analysis of nursing skill-learning. AB - Psychomotor skill-learning is a basic aspect of nursing education. Students are expected to perform skills in relation to patient care. How can nursing instructors optimize skill learning and how can they analyse where a student is going wrong? The critical components of the psychomotor-skill learning process are identified and listed under the control of the instructor or the student. A checklist provides for mutual examination of the process to see if a problem area can be isolated. The article provides a review of a process which tends to become second nature to experienced nurses, but it remains one of which nursing instructors must be conscious, in order to understand why some students do not learn nursing skills easily or safely. PMID- 6900642 TI - Continuity of care: how far do we go? PMID- 6900641 TI - Developing effective institutional managers in the 1980s--part 2: some new directions. AB - In the earlier paper (published in the March 1980 issue of the Journal of Advanced Nursing) two dominant themes were developed. One was that the organizational behaviour of nurse managers could be traced to the social defence system learned during early nursing, the other was that many of the assumptions which underpin much of the current thinking on nurse management training can do little either to help them unlearn these early behaviours or to prepare them to take more innovative action in their respective roles. Part 2 analyses some implications of this. The initial discussion examines the purpose of management training and what it is intended to achieve, which embraces the issues of the transfer of course learning back to the workplace and the greater involvement of line managers in the development of their staff. By redefining nursing in terms of open-system boundary management, some new directions are suggested which management trainers may find useful in clarifying and redefining their own task, as well as enabling nurse managers to be more innovative and effective within the constraints of their organizational situations. The implications go beyond just nursing and nurse management training. They are concerned with the wider range of institutions whose task is the throughput of people, and which tend to be managed by groups of professionals. PMID- 6900643 TI - Designing a program of psychological consultation to nurses in a dialysis setting. PMID- 6900645 TI - The common denominators of the emotional responses of home hemodialysis partners. PMID- 6900644 TI - Patient perception of distress associated with hemodialysis--a state survey. PMID- 6900646 TI - An evaluation of ward atmosphere in hemodialysis units. PMID- 6900647 TI - Something of value. PMID- 6900648 TI - Factors related to satisfaction with life for patients on hemodialysis. PMID- 6900649 TI - Stop abuse of the elderly. PMID- 6900650 TI - A holistic approach to the health care of an elderly client. PMID- 6900651 TI - Disorientation - signal or diagnosis. PMID- 6900652 TI - Can a hospital serve as a hospice? PMID- 6900653 TI - Physiological changes affecting psychotropic drug handling in the aged. PMID- 6900654 TI - Course description: the nursing process: ethnicity and aging. PMID- 6900655 TI - Avoiding dualistic treatment of the elderly ill. PMID- 6900656 TI - Adult day care: a Northwest perspective. PMID- 6900657 TI - Care of the aged in the People's Republic of China. PMID- 6900658 TI - Living with cost containment. AB - Cost containment need not have an adverse effect on quality of care. A critical review of policies and practices can reveal possibilities for controlling and containing costs while maintaining or even increasing quality. The author discusses several areas that deserve the attention of nursing administrators and staff. PMID- 6900659 TI - Management by objectives. AB - Management by objectives, a system for stimulating growth and measuring performance in an organization, is explained, and its advantages for nursing management discussed. The author shows how to implement the system and how to make it succeed. Two examples of MBO in nursing are given: staff evaluation and patient care planning. PMID- 6900660 TI - Do nurses really use standard care plans? AB - The authors studied the use of standard care plans in one institution to determine whether and to what extent nurses were actually using them as tools for patient care. The study produced interesting results and suggestions for improvement. After reading this article, nursing administrators may want to promote similar studies in their own institutions. Improvements made as a result of the findings can pave the way for the next step: determining the effect of standard care plans on the quality of nursing practice and patient outcomes. PMID- 6900663 TI - A theoretical framework for primary nursing. PMID- 6900661 TI - Managing change creatively. AB - Change is an ever-present force in the health care environment. The nursing administrator can become a victim of change forces, or can manage them creatively to the benefit of the entire organization. The author presents a tested model for planned change and illustrates its application with a case study. Readers will find the model provides a framework for sound judgment and creative action. PMID- 6900662 TI - Installing a computer-based patient information system. AB - Extensive planning and coordination are the keys to successful implementation of a hospital-wide, computer-based patient information system. With user involvement, problems can be minimized and benefits realized. Nursing administrators can avoid common pitfalls by following the example of one hospital staff in meeting the challenge of computerization. PMID- 6900664 TI - Acquiring foundation funds. PMID- 6900665 TI - A declaration of nursing independence: the relation of theory and research to nursing practice. PMID- 6900666 TI - A new identity: nurse-midwives as authors. PMID- 6900667 TI - Alternative positions for childbirth--Part I: First stage of labor. PMID- 6900668 TI - Implications for primary care providers of occupational health hazards on pregnant women and their infants. PMID- 6900669 TI - The effects of early elective amniotomy on the length of labor and the condition of the fetus. PMID- 6900670 TI - How the public sees nurse-midwives: 1978 news coverage of nurse-midwifery in the nation's press. PMID- 6900671 TI - The important first trimester: an educational approach. PMID- 6900672 TI - Nursing the hypothyroid patient. PMID- 6900673 TI - When the honeymoon is over: dealing with the real world of nursing. PMID- 6900674 TI - Learning the hard way. PMID- 6900675 TI - Pharmacology update: cephalosporin antibiotics - part II. PMID- 6900678 TI - Obesity. PMID- 6900677 TI - Chronic renal failure: end stage renal disease. The nurse's role in hemodialysis. PMID- 6900679 TI - Product update: inexpensive new instrument dramatically increases cardiac arrest victims' survival rate. PMID- 6900680 TI - Continuing education. PMID- 6900681 TI - RN attitude to LPN's. PMID- 6900676 TI - Mechanism and role of furosemide-sensitive K+ transport in L cells: a genetic approach. PMID- 6900682 TI - Multiple pregnancy. PMID- 6900683 TI - [Overview of midwifery activities in the 80's: trends in maternal and child health care in the United States and expectations of the midwives]. PMID- 6900684 TI - [Overview of midwifery activities in the 80's: consumerism in maternal and child health care in the United States. Discussion]. PMID- 6900685 TI - [Diet for patients with pregnancy toxemias]. PMID- 6900686 TI - [Observations on the curves of the striae of pregnancy around the navel]. PMID- 6900687 TI - [Achievements by a free course of health education for expectant mothers conducted by a private organization]. PMID- 6900688 TI - [Instructions for new mothers on breast feeding]. PMID- 6900689 TI - [Case report. Nursing of a patient with severe pregnancy toxemia and a complicated social background]. PMID- 6900690 TI - [Overview of midwifery activities in the 80's: future of obstetrical care. A discussion]. PMID- 6900691 TI - [Pregnancy extending beyond the expected date. (1)]. PMID- 6900692 TI - [Impressions of the clinical training in obstetrical nursing--the maternal nature and my future task]. PMID- 6900693 TI - [Science of symptoms. Edema: diseases causing edema and the mechanisms of development of edematous conditions]. PMID- 6900694 TI - [Science of symptoms. Edema: physiological topics concerning edema]. PMID- 6900695 TI - [Science of symptoms. Edema: treatment of edema--classification of edema and key points in clinical management]. PMID- 6900696 TI - [Science of symptoms. Edema: systemic edema, ascites and clinical care--nephrotic syndrome and reinfusion of the ascitic fluid]. PMID- 6900697 TI - [Bacteriological study of disinfection of the fingers. I. Bacteriological study of the fingers]. PMID- 6900698 TI - [Bacteriological study of disinfection of the fingers. II. Bacteriological study of hand washing]. PMID- 6900699 TI - [Rehabilitation in fractures (2)]. PMID- 6900700 TI - [Roy's adaptation theory--III. Psychological and social adaptation processes]. PMID- 6900701 TI - [Psychological rehabilitation of the amputee--II]. PMID- 6900702 TI - [Esophageal cancer and its treatment]. PMID- 6900703 TI - [Nursing of a patient with a vocalization disorder due to cancer of the cervical esophagus]. PMID- 6900705 TI - [Pathophysiology of nausea and vomiting]. PMID- 6900706 TI - [Physiology of gastric motion and vomiting actions]. PMID- 6900707 TI - [Various types of vomiting, therapeutic agents, and their modes of administration]. PMID- 6900704 TI - [Problems concerning care of thoracic drainage following esophagectomy]. PMID- 6900708 TI - [Nausea and vomiting following anesthesia and their care]. PMID- 6900709 TI - [Care of children with cerebral palsy and the role of the nurse]. PMID- 6900710 TI - [Roy's adaptation theory - VI. Bases of nursing diagnosis and nursing intervention]. PMID- 6900712 TI - [Current trends in colostomy and the associated equipment]. PMID- 6900711 TI - [The psychological rehabilitation of the amputee. IIII]. PMID- 6900713 TI - [Complaints of the patients with colostomy and their management]. PMID- 6900714 TI - [Protection of the skin of the patient with colostomy. (1). The general basic care]. PMID- 6900716 TI - [Protection of the skin of the patient with colostomy. (3). Care using "Barricare": for the protection of the skin]. PMID- 6900715 TI - [Protection of the skin of the patient with colostomy. (2). Use of karaya gum products for the protection of the skin]. PMID- 6900717 TI - [Innovation in enema therapy and nursing]. PMID- 6900718 TI - [Kock's continent ileostomy - its outline and nursing]. PMID- 6900719 TI - [Process leading up to establishment of self-care in defecation following Kock's continent ileostomy]. PMID- 6900720 TI - [Voice of ostomy patients - designs and innovation in self care]. PMID- 6900721 TI - [Development of pain and associated reactions]. PMID- 6900722 TI - [Mechanisms involved in pain]. PMID- 6900723 TI - [Therapy specifically designed to control pain]. PMID- 6900724 TI - [Report on pain following abdominal surgery in the field of gynecology]. PMID- 6900725 TI - [Analgesia using morphine as the major component and its adverse effects]. PMID- 6900726 TI - [Nursing of a child with Wilson's disease involving the cranial nerves]. PMID- 6900727 TI - [Improvement in the functional difficulties following total resection of the maxilla - use of a cover for the defective palate]. PMID- 6900729 TI - [Roy's adaptation theory - V. Case study and comprehensive observation]. PMID- 6900728 TI - [Nursing of a patient with manic-depressive psychosis with obstructive jaundice]. PMID- 6900730 TI - [The psychological rehabilitation of the amputee]. PMID- 6900731 TI - [Necessity of hypotheses in case studies]. PMID- 6900732 TI - [Significance and utilization of hypotheses in case studies]. PMID- 6900733 TI - [Process from the case evaluation leading up to "research" and "hypotheses"]. PMID- 6900734 TI - [Comparison among case studies in nursing and in other areas of studies. A discussion]. PMID- 6900735 TI - [Nursing concerning childbirth]. PMID- 6900736 TI - [Problems of weighting the hypotheses in case studies]. PMID- 6900737 TI - [Conference on a case study, "Nursing concerning childbirth": data to be recorded]. PMID- 6900738 TI - [Book review by discussion: "The law and the expanding nursing role" edited by Bullough B]. PMID- 6900740 TI - [Entrance examinations at nursing schools]. PMID- 6900739 TI - [Attitude of nursing students and nursing education: results of a nationwide survey]. PMID- 6900741 TI - [A survey of scholastic achievements of nursing students. 1. Day students in a course leading to a nursing degree]. PMID- 6900742 TI - [Regional characteristics of nursing schools and movements of students after graduation. 1. On the applicants to Nara Prefectural Medical College School of Nursing]. PMID- 6900743 TI - [Study on the role of the school nurse: for the health of each pupil]. PMID- 6900744 TI - [Teaching of the comprehensive nursing theory based on class discussion of course outline. (3). With special reference to nursing technology]. PMID- 6900745 TI - [An example of clinical training in obstetrical nursing. (2). Re-evaluation of training in obstetrical nursing starting early in the clinical teaching program]. PMID- 6900746 TI - [Autopsy study in nursing education: involvement of the instructor in the autopsy training]. PMID- 6900748 TI - [A scene with illness. 3. Cancer patients encountered in daily life]. PMID- 6900747 TI - [A survey on the knowledge of nursing students on alcoholism]. PMID- 6900749 TI - [New curriculum and educational research]. PMID- 6900750 TI - [International comparison of the contents of public health education at the college level: a multivariate analysis]. PMID- 6900751 TI - [Changes in students' viewpoint on play by hospitalized children: observation of spontaneous behaviors of children]. PMID- 6900752 TI - [Operation of an educational camp]. PMID- 6900753 TI - [Teaching of comprehensive nursing theory based on class discussion of the course outline. (4). With special reference to nursing technics]. PMID- 6900754 TI - [A scene with illness. 4. Pentazocine dependence]. PMID- 6900756 TI - [Diary of a novice nurse in a pediatric ward]. PMID- 6900755 TI - [Background and the origin of an explosive event. 1. Introduction]. PMID- 6900757 TI - [Education and the study of education in the future: application of an educational theory gained from experience]. PMID- 6900758 TI - [A new kind of nurse: tomorrow's approach to learning]. PMID- 6900759 TI - [Preserving the essence of nursing in a technological age]. PMID- 6900760 TI - [New age for education--creation of an open environment for learning. Topics in the educational field]. PMID- 6900761 TI - [Understanding of the "object"--observation of the daily life as an aspect of health]. PMID- 6900763 TI - [Background and the origin of an explosive event. 2. Maxim in expressing sympathy. 1]. PMID- 6900762 TI - [Scen with illness--5. Smile of a dying patient]. PMID- 6900764 TI - [Financing of public health clinics: transfer of its financial source from the central government to local tax revenues. A thought on the future of the public health clinic]. PMID- 6900765 TI - [Implication of the transfer of financial source for maintaining the public health clinic personnel to local tax revenues: a campaign to resist change]. PMID- 6900767 TI - [Survey theories for public health nurses. (3), Methods for planning surveys]. PMID- 6900766 TI - [Health promotion policies and public health nursing activities - health promotion policies for the citizens and the problems of local public health centers]. PMID- 6900768 TI - [Primary health care in europe (3)]. PMID- 6900769 TI - [High risk babies and cerebral palsy in Memuro-machi]. PMID- 6900770 TI - [Health care activities in the past 4 years at a village in the outskirts of Matsue City]. PMID- 6900771 TI - [Public health nursing activities at Nuyzen-machi (Toyama Pref.). Activities based on the cooperation of the inhabitants]. PMID- 6900772 TI - [Public health nursing activities supported by and participated in by the citizens. Discussion]. PMID- 6900773 TI - [Deep appreciation toward public health nurses: women's organization participating in the health promotion activities for the local population. Discussion]. PMID- 6900774 TI - [Public health activities related to daily life: an interview with the health award winning promotors of the activities]. PMID- 6900775 TI - [Surveying theory for public health nurses. (4). Preparation of questionnaires and sampling]. PMID- 6900778 TI - [Survey on the status of pregnant women in Takasago City]. PMID- 6900777 TI - [Survey on development of 3-year-olds conducted by Izumi Health Clinic--including mother's emotional attitudes toward child rearing]. PMID- 6900776 TI - [Conditions of pregnant women in a city--findings through counseling at the time of registration of pregnancy]. PMID- 6900779 TI - [Evaluation of methods of instruction in preparation of case reports by public health nursing students]. PMID- 6900780 TI - Adapting the birthing center concept to a traditional hospital setting. PMID- 6900781 TI - Pleasure and purpose: the sensuousness of breastfeeding. AB - By examining sexuality in breastfeeding as a reinforcement to ensure the continuity of the human species as well as promoting spacing between pregnancies, the authors review cross-cultural perspectives, physiology, and research on this topic. Individual responses from breastfeeding women are also reported to enlarge the nurse's understanding of a dimension of human behavior not usually acknowledged. PMID- 6900782 TI - Family-centered maternity units--fact or fiction? AB - The author describes discrepancies between nursing education and institutional practices in the area of family-centered maternity care, and questions current limitations in FCMC. The maternity nurse is urged to implement changes which will result in a rewarding childbirth experience in a medically safe environment. PMID- 6900783 TI - Milk let-down. PMID- 6900784 TI - Nursing ethics. PMID- 6900785 TI - Bacterial colonization in neonates with sibling visitation. AB - The effect of postpartum sibling visitation on the incidence of bacterial colonization in neonates was investigated in a 25-bed ob/gyn unit at a military hospital. The visitation policy allowed siblings to visit with the infant at the mother's bedside, and siblings were allowed unrestricted contact with the infant after handwashing with an iodine scrub preparation. Data comparison revealed bacterial colonization on discharge in 70% of 214 control infants (admitted prior to sibling visitation program) and 67% of 182 study infants. It was concluded that postpartum sibling visitation did not increase the incidence of bacterial colonization in neonates. PMID- 6900787 TI - Early mother-infant contact and infant temperature stabilization. AB - Thirty-four healthy mother-infant dyads were divided into two groups to determine the effect of postdelivery skin-to-skin contact on infant temperature stabilization. Nineteen control infants were placed in heated cribs, while 15 study infants were given immediate and extended physical contract with their mothers. Axillary and rectal temperatures were measured five minutes after birth and one hour after the infants left the delivery room. The results indicate that separating normal newborns from their mothers for the purpose of stabilizing temperature may not be necessary. PMID- 6900786 TI - Gravidas' responses to realtime ultrasound fetal image. AB - One hundred women in various stages of pregnancy were questioned before and after viewing their fetuses through realtime ultrasonographic scanning. For the majority of these women, perceptions of the fetus changed following this visualization. Viewing gave some a greater sense of attachment to the fetus, but for a few, this attachment also gave a greater sense of vulnerability with regard to the outcome of the pregnancy. PMID- 6900788 TI - Pros and cons of douching: the nurse's role in counseling. PMID- 6900790 TI - [Utilization of reciprocity in client contracts]. PMID- 6900791 TI - [Premenstrual syndrome]. PMID- 6900789 TI - Education for the childbearing year: comprehensive application of psychoprophylaxis. AB - The childbirth educator's role is one of intervention in a "normal life crisis". Through comprehensive psychoprophylactic education and counseling throughout the childbearing year, rather than just in third trimester class, the childbirth educator can help parents accommodate this transitional phase of their lives. PMID- 6900792 TI - [Midwifery in Europe]. PMID- 6900793 TI - [Not unconditionally]. PMID- 6900794 TI - [Hazardous childbirth]. PMID- 6900795 TI - [Breast cancer and pregnancy]. PMID- 6900797 TI - [The status of an educational patient]. PMID- 6900796 TI - [International breast feeding symposium, Tel Aviv, Israel, 24-28 February 1980]. PMID- 6900798 TI - [Public health and children]. PMID- 6900799 TI - [Pregnancy in women with a chronic disease]. PMID- 6900800 TI - [Midwife-specialized nurse and care of gynecologic infections]. PMID- 6900801 TI - [Welcome to the 20th anniversary festival of the hospital school for midwives]. PMID- 6900802 TI - [From abroad: primary nursing at Beth Israel Hospital Boston]. PMID- 6900803 TI - [On facing "refusal" by patient]. PMID- 6900804 TI - [Journey to Kenya]. PMID- 6900805 TI - [The process of recognition and response to the refusal by patients]. PMID- 6900806 TI - [Structure of "refusal"]. PMID- 6900808 TI - [The meaning of refusal]. PMID- 6900807 TI - [Let's investigate the meaning of "refusal" by patients]. PMID- 6900810 TI - [Learning from case studies - nurses are training for home care practice. 12]. PMID- 6900809 TI - [Helping patients to be hospitalized comfortably]. PMID- 6900811 TI - [Report from the hospital for the aged. 2]. PMID- 6900814 TI - [How to select a specific nursing action]. PMID- 6900812 TI - [Profile: a nurse published "History of the psychiatric hospital" at her own expense]. PMID- 6900813 TI - [Endorphins]. PMID- 6900815 TI - [The way the art of nursing should be]. PMID- 6900816 TI - [How to strengthen the art of nursing]. PMID- 6900817 TI - [What is the art of nursing]. PMID- 6900818 TI - [The art of nursing - nursing technology between patients and nurses]. PMID- 6900819 TI - [Implementation of standards of practice in gerontological nursing]. PMID- 6900820 TI - [From abroad: mother and child health in Switzerland]. PMID- 6900821 TI - [Report from the hospital for the aged. 3]. PMID- 6900822 TI - [Visit to the Danish Nurses' Organization]. PMID- 6900823 TI - [Profile: a Japanese Brazilian nurse comes to see Japanese nursing]. PMID- 6900825 TI - [How to listen to patients]. PMID- 6900824 TI - [Relationship between the speaker and the listener]. PMID- 6900826 TI - [A thought on "listening"]. PMID- 6900827 TI - ["Listening with the body" and "listening to the body"]. PMID- 6900829 TI - [Listening to patients]. PMID- 6900828 TI - [The weight of listening to patients]. PMID- 6900830 TI - [Continuing education in America - accountability of professional nurses]. PMID- 6900831 TI - [Helping patients to take a bath]. PMID- 6900832 TI - [Report from the hospital for the aged. 4]. PMID- 6900833 TI - [Profile: a nurse wrote a human document, "The children's ward"]. PMID- 6900834 TI - [Intra-aortic balloon pumping, IABP]. PMID- 6900835 TI - [Blood kallikrein-kinin system in acute viral hepatitis]. PMID- 6900837 TI - [Perhaps still a lack in continued education: breast feeding experiences in the hospital]. PMID- 6900836 TI - [Examples for suicide research in adolescents. Distressed by home and school]. PMID- 6900838 TI - [Sim One--the artificial patient]. PMID- 6900839 TI - [Discussion contribution for students and faculty. Professional education as a socialization process]. PMID- 6900840 TI - Effects of occupational exposure to dust on the respiratory system of cement workers. PMID- 6900843 TI - [Social changes and changes in attitude of the nursing students]. PMID- 6900842 TI - [Nursing students among the young generation--their thought structures and relationship with the instructors]. PMID- 6900841 TI - [The thought structure of modern youths and their concepts of the profession]. PMID- 6900844 TI - [Increase in nursing students' desire to learn and associated changes in their attitude to nursing]. PMID- 6900845 TI - [Understanding of nursing as a profession]. PMID- 6900846 TI - [The logic of the checklist--self evaluation by the student as a basis of learning]. PMID- 6900847 TI - [Current status of nursing homes in the United States--data on the patient population and the nursing profession]. PMID- 6900848 TI - [Life science. (1). Definition of life science]. PMID- 6900849 TI - [Pediatric bedside conference. (4). Nervous system diseases (2), liver disease (2), and hematologic disease (2)]. PMID- 6900850 TI - [Primary health nursing in England. 1. Definition of primary health care]. PMID- 6900851 TI - [On continuing education in Japan]. PMID- 6900852 TI - [Nursing leadership seminars: decision making and priorities 1979. 1. Nurse leadership and continuing education. 1]. PMID- 6900853 TI - [Instruction on "technic in development of the nursing process" using the history of the hospitalized patient]. PMID- 6900855 TI - [Continuity of nursing and carry-over of nursing technics - through practical experiences]. PMID- 6900854 TI - [Various phases of nursing technics applied in health facilities and regional nursing activities]. PMID- 6900856 TI - [Nursing technology in home nursing, by visiting]. PMID- 6900857 TI - [Training in nursing technology and introduction of the volunteer system - the home nursing class and organization of home care group by volunteers]. PMID- 6900859 TI - [Study on nursing of patients with systemic lupus erythematosus - 1]. PMID- 6900858 TI - [Practice of home care and nursing technics practiced by family members]. PMID- 6900860 TI - [Human science. Life science. 2. Defense mechanism of the body]. PMID- 6900861 TI - [Pediatric bedside conference. 5. Malignant tumors (1) and congenital heart diseases (2) in children]. PMID- 6900863 TI - [Re-evaluation of basic nursing education - the system, faculty, and students]. PMID- 6900862 TI - [Primary health care in England. 2. Implementation of the National Health Service]. PMID- 6900864 TI - [Nurse leadership seminars: decision making and priorities 1979. Nurse leadership from the viewpoint of continuing education - 2]. PMID- 6900865 TI - [The concept of training in psychiatric nursing - with special reference to training of students dressed in street clothes]. PMID- 6900866 TI - Getting organized: a simple recipe for social change. PMID- 6900867 TI - Alternatives to the NHS. PMID- 6900869 TI - Stuttering. PMID- 6900868 TI - Team work with the Army in child care. PMID- 6900870 TI - Iatrogenic problems of the newborn. PMID- 6900871 TI - Personally speaking: maternal deprivation. PMID- 6900872 TI - The future of family planning. PMID- 6900873 TI - Antenatal diagnosis of fetal abnormality. PMID- 6900874 TI - Doctors, prisoners and state - a conflict of interest? PMID- 6900875 TI - Family planning - is it working in the NHS? PMID- 6900876 TI - The initiation of lactation. PMID- 6900877 TI - Assessing the needs of an ethnic community. PMID- 6900878 TI - Child health record booklet. PMID- 6900879 TI - Personal view: where are marriages made? PMID- 6900880 TI - Physiotherapy in the community. PMID- 6900881 TI - Antenatal care. PMID- 6900882 TI - Antenatal care: have Dr Ballantyne's aims been achieved? Part 2. PMID- 6900883 TI - Voluntary self-help for parents under stress in Britain. PMID- 6900884 TI - Health education without tears. PMID- 6900885 TI - Womens Royal Voluntary Service. PMID- 6900886 TI - Nursery schools. PMID- 6900887 TI - Man--pregnancy and labour. PMID- 6900888 TI - Attitudes of men towards labour and delivery. PMID- 6900890 TI - DNA--the amazing helix. PMID- 6900889 TI - Volunteers in the primary care team. PMID- 6900891 TI - "Learning and teaching--part of every nurse's business". PMID- 6900892 TI - Midwifery standards. PMID- 6900893 TI - Midwifery training: the views of newly qualified midwives. PMID- 6900894 TI - Fertility control. PMID- 6900896 TI - Low birth weight babies in Calderdale. PMID- 6900895 TI - "Patients first"--a consultative paper on the structure and management of the National Health Service in England and Wales. PMID- 6900897 TI - From educating the diabetic client to the MoNA clinical sessions. PMID- 6900898 TI - Accessability and continuing education: how do you get there from here. PMID- 6900899 TI - Continuing education in Missouri. PMID- 6900900 TI - Improving patient education in a small community hospital: a packet system for patient teaching. PMID- 6900901 TI - Current concepts in immunology: the alternative pathway of complement--a system for host resistance to microbial infection. PMID- 6900902 TI - Orthopaedics for theatre staff - Part 2. The hip joint: pathological conditions. PMID- 6900903 TI - Big is best? A study into the optimum size of multi-suite operating departments. PMID- 6900906 TI - C.N.N.T. The Council of Nephrology Nurses and Technicians. PMID- 6900904 TI - Court reverses decision. PMID- 6900905 TI - Donkeys, carrots, and sticks. Some approaches to employee motivation. PMID- 6900907 TI - AANNT Chapters Committee activities. PMID- 6900909 TI - Teaching CAPD. PMID- 6900908 TI - Patient and technician: a dual role. PMID- 6900911 TI - The psychological adaptation of End Stage Renal Disease: a review and a proposed new model. PMID- 6900910 TI - Anemia associated with chronic renal failure and chronic dialysis. PMID- 6900913 TI - Medication errors: use accurate measuring devices for oral medications. PMID- 6900912 TI - Why physical assessment? PMID- 6900914 TI - About your letters of recommendation. PMID- 6900915 TI - When everything is "fine, just fine". PMID- 6900916 TI - Helping diabetics live with their neuropathies. PMID- 6900917 TI - Meeting the challenge of fistulas and draining wounds. PMID- 6900918 TI - Long term respiratory care in the I.C.U. Nursing grand rounds. PMID- 6900919 TI - A new treatment for a new problem: acetaminophen overdose. PMID- 6900921 TI - Which patient on your unit might get a pressure sore? Here's the tool that can tell you. PMID- 6900920 TI - Examining the external eye. Part 2. PMID- 6900922 TI - Mrs. Ladley thought she could care for her husband better than we could. PMID- 6900923 TI - Keeping infections down when risks go up. PMID- 6900924 TI - Test your knowledge of current nursing practice. Part 3. PMID- 6900925 TI - Nursing patients from different cultures. PMID- 6900926 TI - Managing an arterial line. PMID- 6900927 TI - The returning-to-school syndrome. PMID- 6900928 TI - Sex after radical prostatectomy. PMID- 6900929 TI - Cycle trauma: nursing's three key roles. PMID- 6900930 TI - Meeting families' needs helps you meet ICU patients' needs. PMID- 6900931 TI - What to do when the patient's in hypertensive crisis. PMID- 6900932 TI - When your patient has a shoulder arthroplasty here's how to help. PMID- 6900933 TI - Predicting a patient's anxiety level during labor: a two-part assessment tool. PMID- 6900935 TI - Test your knowledge of current nursing practice--Part 4. PMID- 6900934 TI - The battered wife. PMID- 6900936 TI - How to test your patient's hearing acuity. PMID- 6900938 TI - Six quick questions will help you decide: are you promotable? PMID- 6900937 TI - Dantrium: the approved drug to control malignant hyperthermia. PMID- 6900939 TI - The outsider. PMID- 6900940 TI - Peer pals: overcoming the obstacles to leadership development. PMID- 6900941 TI - Mentoring: an encounter of the leadership kind. PMID- 6900942 TI - Individual vs institutional licensure: part of the credentialing dilemma. PMID- 6900943 TI - World hunger: a nursing issue. PMID- 6900945 TI - The nursing network - a united front. PMID- 6900944 TI - Leadership: a review of the literature and theoretical framework for nursing courses. PMID- 6900947 TI - The role and function of nursing auxiliaries. PMID- 6900946 TI - A forum for discussion: is nursing an adjective or a noun? PMID- 6900948 TI - The health professions in Europe. 1. EEC directives. PMID- 6900949 TI - Nursing with the forces: 2. The QAs. PMID- 6900950 TI - Short term absence--another view. PMID- 6900951 TI - Legal notes: remedies for unfair dismissal. PMID- 6900952 TI - A place for simulation in nurse education. PMID- 6900953 TI - Reduction in the working hours of nurses. PMID- 6900954 TI - Cash and care: a question of priorities. PMID- 6900955 TI - Management development: problems and progress. PMID- 6900956 TI - Education: sexual attitudes factor. PMID- 6900957 TI - Nursing with the Forces: 1. The RAF. PMID- 6900958 TI - Education--where are we going? PMID- 6900959 TI - "Multiple choice": our system from (A) to (Z). PMID- 6900960 TI - Managing an education division. PMID- 6900961 TI - Education--a continuing concern. PMID- 6900963 TI - How much risk to the pound? PMID- 6900962 TI - Precision foundry hazards. PMID- 6900965 TI - Production measures put lives of Polish miners at risk. PMID- 6900964 TI - The epileptic worker. PMID- 6900966 TI - Findings of joint NIOSH/OSHA Work Group concerning health effects of asbestos. PMID- 6900967 TI - What is the role of the occupational health nurse in the 1980s--one nurse's opinion. PMID- 6900968 TI - The Catherine R. Dempsey Memorial Lecture. Occupational health nursing: a perspective for 1980. PMID- 6900969 TI - Legislator tells nurses to put their house in order. PMID- 6900970 TI - [Confusion syndrome--nursing staff's role. 1]. PMID- 6900972 TI - [Community services for psychiatric patients and their effects on nursing in England and Scotland]. PMID- 6900971 TI - [Clinical instruction]. PMID- 6900973 TI - [Humanism in the hospital--a phase or a challenge?]. PMID- 6900974 TI - [Care of a patient with lymphogranulomatosis]. PMID- 6900975 TI - [Confusion syndrome--nursing staff's role. 2]. PMID- 6900976 TI - [Theoretical background for quality evaluation of care]. PMID- 6900977 TI - [Forms of depression--their diagnosis and treatment]. PMID- 6900978 TI - [Masked depression in an internal medicine department]. PMID- 6900979 TI - Assessment and intervention: the depressed school-age child. PMID- 6900980 TI - Observed behaviors of preschoolers to intensive care. PMID- 6900981 TI - Factors involved with patient compliance. PMID- 6900982 TI - Pediatric management problems (toilet training). PMID- 6900983 TI - A "good beginning" for families. PMID- 6900984 TI - Migraine headaches in children. PMID- 6900985 TI - Pediatric drug information. A potpourri: scabies, hazards of refrigerating medications, and aspirin--tartrazine dye cross sensitivity. PMID- 6900986 TI - Depression in children: reasons and risks. PMID- 6900987 TI - Nursing interventions in anorexia nervosa. PMID- 6900988 TI - Meeting the spiritual needs of hospitalized psychiatric patients. PMID- 6900989 TI - A psychotherapist is a psychotherapist. PMID- 6900991 TI - Pathological narcissism. PMID- 6900990 TI - A psychotherapist is a psychotherapist. PMID- 6900992 TI - The psychiatric clinical specialist: the progression of a specialty. PMID- 6900993 TI - The changing student population in diploma programs. PMID- 6900994 TI - Counseling and other support services for adult students. PMID- 6900995 TI - Counseling and student services for the changing student population. PMID- 6900996 TI - Considerations in recruitment, admissions, and financial aid. PMID- 6900997 TI - Recruitment and admission of a varied student population. PMID- 6900998 TI - Educational practices to accommodate a diverse student body. PMID- 6900999 TI - Concerns of an older male student. PMID- 6901000 TI - Concerns of a traditional student. PMID- 6901001 TI - Needs and concerns of a mature student. PMID- 6901002 TI - Commuting, study, and a preschool child. PMID- 6901003 TI - On with generativity! PMID- 6901004 TI - Determination--the key to success. PMID- 6901005 TI - A profession in search of definition. PMID- 6901006 TI - Support group for ICU nurses. PMID- 6901007 TI - Strategies to improve students' attitudes to research. PMID- 6901008 TI - From graduate students to faculty: a simulation. PMID- 6901010 TI - Student experience in voluntary health care agencies. PMID- 6901009 TI - The chronic psychiatric patient in the community--a model of care. PMID- 6901011 TI - Curriculum development in continuing education: option or necessity? PMID- 6901012 TI - Perceptions of problematic behavior by Appalachians, mental health professionals, and lay non-Appalachians. AB - This study postulated that the culture of a group influences the labels that group places on behavior. In the case of problematic behaviors, culture influences whether the behaviors are labeled mental illness. Three groups of randomly selected respondents representing two cultural groups were interviewed to compare the labels placed on problematic behavior. One group represented the Appalachian culture (N = 50). Two groups represented the predominant American culture: mental health professionals (N = 54) and a lay group or non-Appalachians (N = 50). Each respondent was interviewed personally, using a structured questionnaire consisting of vignettes that described various problematic behaviors. It was hypothesized that there would be a significant difference between cultural groups in the labeling of problematic behaviors. Data were analyzed by a oneway analysis of variance, and a qualitative analysis was done. Findings supported the hypothesis. No significant differences were found between the mental health professionals and the lay group of non-Appalachians; however, there was a significant difference between each of these groups and the Appalachians. Behaviors that were labeled as mental illness by the mental health professionals and the lay non-Appalachians were labeled as lazy, mean, immoral, criminal, or psychic by the Appalachians. Kinds of management recommended for these behaviors by the two cultural groups differed. Whereas mental health professionals and lay non-Appalachians recommended some type of psychiatric management, Appalachians recommended punishment by either the social group or the legal system, or they recommended that the behaviors be tolerated. PMID- 6901013 TI - Relationship of parent-child communication to child's exploratory behavior and self-differentiation. AB - In a study that investigated the relationship between patterns of acknowledgment in parent--child communication and the child's exploratory behavior and self differentiation, subjects included 77 healthy perschool children between the ages of 3 years, 3 months and 4 years, 9 months and their mothers. Data on parent- child communication were collected in the home setting during a 30-minute observation in which mothers and children were engaged in a series of semi structured play activities. Maternal responses to their children's assertions were coded as nonevaluative recognition, positive recognition, negative recognition, direction, or nonrecognition. A score on parent--child communication was the ratio of parental nonevaluative recognition and positive recognition combined to parental negative recognition, direction, and nonrecognition combined. Testing of the children on exploratory behavior and self differentiation was done on an individual basis in their respective nursery schools. A low positive correlation (r = .237, p less than .05) between parent- child communication and children's self-differentiation was observed. Contrary to expectation, a slight negative correlation (r = -.101, p greater than .05) between parent--child communication and children's exploratory behavior was observed. Auxiliary analyses of the data, taking into consideration the child's sex, revealed that the negative relationship between parent--child-communication and children's exploratory behavior was characteristic of the mother-daughter dyads only (r = -.325, p = .08). A correlation of .078 (p greater than .05 was obtained for mother--son communication with boys' exploratory behavior. PMID- 6901014 TI - Oral temperature differences in relation to thermometer and technique. AB - The validity of oral temperature measurements depends on use of an appropriate site, a dependable thermometer, and a proper technique. Fifty febrile patients and 50 afebrile volunteers were studied to determine differences in oral temperature measured in three sublingual sites with three brands of electronic thermometers and with mercury thermometers and to learn whether two methods of probe insertion (slow-slide and direct-placement) with electronic thermometers would result in differences in either the temperature reading obtained or the instrument response time. When measured with the rapidly responding electronic thermometers, temperatures in the right and left posterior sublingual pockets were significantly higher (p less than .01) than in the area under the front of the tongue. The difference was approximately .3 degrees F in the afebrile subjects and approximately .4 degrees F in those with fever. With mercury thermometers, however, the temperature differences were small and not statistically significant. There was no significant difference between temperatures measured in the two posterior pockets using either electronic or mercury thermometers. There was some individual variation in the values registered by electronic thermometers at each site, although the differences between the three sites were consistent with all three instruments. Actual temperature values differed between electronic and mercury thermometers. When electronic thermometer probes were inserted into a posterior pocket using a slow slide technique, temperature readings were higher by approximately .1 degree F and were obtained a few seconds faster than when the probe was put directly in place without a prewarming procedure. These differences were statistically significant (p less than .01) but of limited clinical importance. Findings emphasized the importance of using the posterior sublingual pocket as the site for oral temperature measurement and the value of using the same instrument to obtain repeated comparable measurements. PMID- 6901015 TI - Male adolescents' concern about a physical examination conducted by a female. AB - This descriptive study measured degree of concern of 45 healthy male adolescents aged 13 to 17 from three private physicians' offices when they were told that their complete physical examination might be conducted by a female examiner. Degree was measured on a 20-item Likert-type instrument on which areas of concern were categorized as body image, identity, independence, and relatedness. Concern scores were obtained in each of the four categories, and a total concern score was determined. Relationships between the independent variable, age of the participants, and the dependent variables, concerns (body image, identity, independence, relatedness, and total concerns), were determined by Pearson correlations. Relationships were additionally determined between a second independent variable, Tanner stage of physiological sexual development, and the dependent variables. Partial correlation was used to determine relationships between Tanner stage and concerns while holding age constant. As age increased, concerns decreased, and no significant relationship was found between Tanner stage and concerns. Age was such a contributing factor affecting concerns that when partialed out, no significant relationship between Tanner stage and concerns remained. Because female clinicians might expect to seen more concern in younger adolescent males, research is required on how to reduce these concerns. PMID- 6901016 TI - Role transformation of special care unit nurses: a comparative study. AB - To investigate whether special care unit nurses have characteristics different from nurses who work in nonintensive care settings and whether SCU nurses make more effective role transformations than non-SCU nurses, this posthoc descriptive study utilized data from 213 new graduate nurses in their first jobs in eight medical centers across the United States. The 213 nurses were a subsample of 307 new graduate nurses in a parent study that tested effect of a bicultural orientation program in role transformation. The nurses in the subsample worked in one of four nursing areas: medical--surgical, medical--surgical specialty, parent -child, and SCU. They were pretested at six weeks of employment regarding their: professional, bureaucratic, and service role conceptions; total role deprivation; professional, bureaucratic, and bicultural role behavior; self-esteem; and degree of self-actualization. SCU nurses had significantly higher self-actualization scores initially than medical--surgical nurses. Posttesting at nine months of employment included all of the above variables plus measures of empathy and change-agent activity. Performance ratings and resignations were examined at one year of employment. Analyses of variance of the difference scores and posttest only scores showed no significant differences by type of unit except for self actualization. To examine the relationship between the degree of specialization and the variables under study, units were rank ordered according to degree of specialization. Nurses working on units which required the most specialization had significantly higher increases in bicultural scores and self-esteem and trends toward higher increases in bureaucratic role conception and higher performance ratings. However, SCU nurses also had the most decrease in professional role conception scores, least increase in self-actualization scores, least amount of empathy with co-workers, and least amount of effective change agent activity--all undesirable occurrences. PMID- 6901017 TI - Nursing science in transition. AB - Nursing science, the base of knowledge underlying human behavior and social interaction, under normal and stressful conditions, across the life span, is distinguished from its inquiry (research). Inquiry and, especially, methodology have been afforded greater attention than science. The requirements for increased science are noted: communality, colleagueship, and competition among scientists and continuity and confirmation of scientific activity and evidence. PMID- 6901018 TI - Update on nursing research in the West. AB - Work of the Western Council of Higher Education in Nursing, of the Western Interstate Commission for Higher Education, is described. The regional research development project, the regional conferences, compilation of research instruments, and organization of an ethnic nurses' organization which grew out of WCHEN projects, are reviewed. Outcomes of research replication through patient teaching projects, the analysis and planning contract, and the utilization of psychiatric--mental health nursing reasearch are also discussed. PMID- 6901019 TI - Developing and implementing collaborative nursing education research in the South. AB - The project, Nursing Research Development in the South, was designed to facilitate collaborative research in nursing education in the South. Funded by the Department of Health, Education, and Welfare as a three-year project of the Southern Regional Education Board and the Council on Collegiate Education for Nursing, it began in 1977. In the first year, nursing educators and clinicians identified research problems and priorities. Nurse faculty were then invited to conduct studies examining problems in the chosen areas; 78 participated in 19 collaborative research groups. PMID- 6901020 TI - Nursing research and regionalization in the Midwest. AB - This article describes developments in nursing research in the Midwest and events that led to regionalization of nursing activities. It emphasizes the special characteristics of the Midwest that have influenced nursing research, results of federal support programs for nursing research, and centralization of research effort in some schools of nursing. It traces the events leading to regionalization of nursing research, the formation of the Midwest Alliance in Nursing, establishment of the Midwest Nursing Research Society, and anticipation of centralization of regional nursing activities under the aegis of MAIN. PMID- 6901021 TI - Nurses in the political arena. PMID- 6901022 TI - A right to be trained. PMID- 6901023 TI - Taking it easy. PMID- 6901024 TI - Innovation in nurse education. PMID- 6901026 TI - Nurse education and the curriculum. PMID- 6901025 TI - Student--centered learning in nurse education. PMID- 6901027 TI - Nursing care study: treatment without surgery for carcinoma of the breast. PMID- 6901028 TI - A patient with a depressed fracture of the skull. PMID- 6901030 TI - Systems of life No 66. Systems and signs: the cardiovascular system--1. PMID- 6901029 TI - Ethics, nursing and behaviour modification. PMID- 6901031 TI - Student role perception of the primary health care team--1. Overlap--friend or foe? PMID- 6901032 TI - Laparotomy for intestinal obstruction and the anaesthetic nurse's role. PMID- 6901033 TI - Treatment of incontinence. PMID- 6901034 TI - An automatic midstream urine collector. PMID- 6901035 TI - Promoting continence in psychogeriatric patients. PMID- 6901036 TI - A clinical trial of pants and pads used for urinary incontinence. PMID- 6901037 TI - Psychiatry under review--12. Psychiatric nursing--what now? PMID- 6901038 TI - British nurses in Holland. PMID- 6901039 TI - Children as scapegoats. PMID- 6901040 TI - Now you are a mother. PMID- 6901041 TI - Touch. PMID- 6901043 TI - The hospice comes of age. PMID- 6901042 TI - Education: the silent debate. PMID- 6901044 TI - You and your money--1. Banks. PMID- 6901045 TI - Bring on the experts. PMID- 6901046 TI - Nursing care study: acute intermittent porphyria. PMID- 6901047 TI - Terminal pain--1. PMID- 6901048 TI - Pain relief--the nurse's role. PMID- 6901049 TI - The milk run. PMID- 6901050 TI - Deep freezing specialised formula baby foods. PMID- 6901051 TI - Community psychiatric nursing: new patterns of contact. PMID- 6901053 TI - Community psychiatric nursing: a mobile day unit. PMID- 6901052 TI - Community psychiatric nursing. PMID- 6901054 TI - Community psychiatric nursing: child psychiatric day centres. PMID- 6901055 TI - Community psychiatric nursing: senile dementia--community support. PMID- 6901056 TI - Community psychiatric nursing: working from a health centre. PMID- 6901057 TI - Returning turtle. PMID- 6901058 TI - Hospitals should do the sick no harm. 6. Combating infection--3. personal factors. PMID- 6901059 TI - Student role perception of the primary health care team--2. Overlap--guilty or innocent? PMID- 6901060 TI - Death, the child and his family--2. PMID- 6901062 TI - Death, the child and his family--2. Burrswood: the Dorothy Kerin Trust. PMID- 6901061 TI - Death, the child and his family--2. Nursing the dying child at home. PMID- 6901063 TI - Death, the child and his family--2. A stay at Burrswood. PMID- 6901064 TI - Living and learning. PMID- 6901065 TI - Continuing development. PMID- 6901066 TI - Taking action. PMID- 6901067 TI - What is a co-ordinator? PMID- 6901068 TI - Dear Mrs Thatcher. PMID- 6901069 TI - In-service training--1. In-service training and all that. PMID- 6901071 TI - In-service training--1. A computerised survey of learning needs. PMID- 6901070 TI - In-service training--1. In-service training for nurses and other professionals. PMID- 6901072 TI - Nursing care study: an accident on the golf course. PMID- 6901073 TI - You and your money--2. Savings. PMID- 6901074 TI - Alcoholism: a family illness. PMID- 6901075 TI - Sources and resources. PMID- 6901076 TI - Information please! PMID- 6901078 TI - An inquiry into the ward learning environment. PMID- 6901079 TI - Psychiatry in a cold climate. PMID- 6901077 TI - Dominica's Hurricane David. PMID- 6901080 TI - No half measures. PMID- 6901081 TI - Music has charms. PMID- 6901082 TI - A critical evaluation of some extensible bandages in current use. PMID- 6901085 TI - In-service training - 2. Meeting the challenge. PMID- 6901083 TI - Bandaging techniques and treatment for other minor injuries. PMID- 6901084 TI - Total hysterectomy and bilateral salpingo--oophorectomy for endometriosis. PMID- 6901087 TI - You and your money - 3. Protection. PMID- 6901086 TI - In-service training - 2. The role and function of the in-service training officer. PMID- 6901088 TI - Systems of life No 67. Systems and signs: the cardiovascular system - 2. PMID- 6901089 TI - Homeless families: a scheme of notification to ensure effective care. PMID- 6901090 TI - Dying is no disgrace. PMID- 6901091 TI - Why don't nurses read? PMID- 6901092 TI - Plagiarism - a form of stealing. PMID- 6901094 TI - A noisy noise annoys. PMID- 6901093 TI - Who wants to be a manager. PMID- 6901095 TI - On location--1. Nursing at the seaside. PMID- 6901096 TI - A new system for administering cytotoxic drugs. PMID- 6901097 TI - A patient with manic depressive psychosis. PMID- 6901098 TI - You and your money - 4. Insurance. PMID- 6901099 TI - Creating a climate for careers. PMID- 6901100 TI - Nurses' role performance--a research study. PMID- 6901101 TI - A dynamic approach to nursing. PMID- 6901102 TI - Some searching questions. PMID- 6901103 TI - Nursing--a student's view point. PMID- 6901104 TI - Humidification of inhaled gases. PMID- 6901105 TI - Leave me to my awful ways! PMID- 6901106 TI - Air ambulance: homeward bound. PMID- 6901107 TI - Positive health. Hygeia rules: OK? PMID- 6901108 TI - Psychology. 5. Is anyone there? PMID- 6901109 TI - Male infertility: improving quality and quantity. PMID- 6901111 TI - Self-help therapy: never mind the dirt! PMID- 6901110 TI - Feeding open wounds: distress relieved. PMID- 6901113 TI - Management. Employee turnover: how do you stop them leaving? PMID- 6901112 TI - Community nursing. Statistics: hidden messages. PMID- 6901114 TI - Nursing care study. Epilepsy: an unacceptable illness. PMID- 6901115 TI - Brookwood: what really happened. PMID- 6901116 TI - NUPE vents its anger at low pay and cuts. PMID- 6901117 TI - Where now for psychiatric nursing? PMID- 6901118 TI - Where now for psychiatric nursing? The Scottish situation. PMID- 6901119 TI - Where now for psychiatric nursing? Who holds the reins? PMID- 6901121 TI - How it may be just the job! PMID- 6901120 TI - Where now for psychiatric nursing? Changing scenes. PMID- 6901122 TI - Influencing health policies: a case of not-so-gentle persuasion. PMID- 6901123 TI - Stress and relaxation: curbing the caveman in us. PMID- 6901125 TI - Psychology. 6. Acting on attitudes. PMID- 6901126 TI - Psychology: the unexplored alliance. PMID- 6901124 TI - Students' forum--gastrointestinal tract. PMID- 6901127 TI - Nursing care study. Myocardial infarction: six days of uphill struggle. PMID- 6901128 TI - COHSE Annual Conference. PMID- 6901129 TI - Cowboys, nurses and doctors. PMID- 6901130 TI - From a learner's point of view. PMID- 6901131 TI - Treating burns: pig skin beats burns. PMID- 6901133 TI - Down Memory Lane: suffer the little children. PMID- 6901132 TI - Picture quiz: cancer of the lung. PMID- 6901134 TI - Community nursing. Stoma care in Scotland: patients' views on stoma care. PMID- 6901135 TI - Nursing care study. Subacute bacterial endocarditis: Louise's losing battle. PMID- 6901136 TI - Fighting with Flowers. PMID- 6901137 TI - Which way for Whitley. PMID- 6901138 TI - RCM Meetings: time for a change? PMID- 6901139 TI - RCM Meetings: bottleless babies. PMID- 6901140 TI - Occupied with the staff's welfare. PMID- 6901141 TI - Who are the real friends of the NHS? PMID- 6901142 TI - Marital therapy: a risky business. PMID- 6901143 TI - The vegetarian diet: animal, vegetable, mineral. PMID- 6901144 TI - Library service: shelving a learner's problem. PMID- 6901145 TI - Students' forum. PMID- 6901146 TI - Incontinence: a vital balance. PMID- 6901147 TI - Nursing care study. Resocialisation: rolling the dice towards success. PMID- 6901149 TI - N.D. FNP's: extenders of 'caring'. PMID- 6901148 TI - Legal control of drugs and generic drugs. PMID- 6901150 TI - Alcohol education: children of alcoholics. PMID- 6901152 TI - [Full realization of the social policy of the Polish United Workers' Party]. PMID- 6901151 TI - [State of the blood kallikrein-kinin system in patients operated on for pulmonary tuberculosis]. PMID- 6901153 TI - [Duties of health personnel]. PMID- 6901154 TI - [Planned and active parenthood]. PMID- 6901156 TI - [I have an idea]. PMID- 6901155 TI - [Following myocardial infarct]. PMID- 6901157 TI - [Advances in radiotherapy]. PMID- 6901158 TI - [The first diplomas in graduate nursing education]. PMID- 6901159 TI - [Intensive care unit]. PMID- 6901160 TI - [How to efficiently run a health resort]. PMID- 6901162 TI - [Blood groups and their significance]. PMID- 6901161 TI - [Feeling different]. PMID- 6901164 TI - [To do away with the nurse's cap...]. PMID- 6901163 TI - [Facial and skull injuries in children]. PMID- 6901165 TI - [Reflections]. PMID- 6901166 TI - [Professional practice]. PMID- 6901167 TI - [Honest and persistent efforts will lead to an improvement in the nation's health]. PMID- 6901168 TI - [Cooperation]. PMID- 6901169 TI - [Professional improvement]. PMID- 6901171 TI - [Planned and active parenthood]. PMID- 6901170 TI - [Delivery ward]. PMID- 6901172 TI - [Advances in the diagnosis and treatment of calcium lithiasis]. PMID- 6901173 TI - [Meeting the needs of hospitalized patients]. PMID- 6901174 TI - [The nurse assumes her functions following graduation]. PMID- 6901175 TI - [The Iwonicz spa]. PMID- 6901176 TI - [Serological conflict]. PMID- 6901177 TI - [Diseases of the esophagus]. PMID- 6901178 TI - [Doing away with the nurse's cap. 3]. PMID- 6901179 TI - [Reflections]. PMID- 6901180 TI - Stroke: diagnosis and management: foreword. PMID- 6901181 TI - Noninvasive carotid artery testing and the asymptomatic bruit. AB - Noninvasive carotid testing in the stroke patient has some, although limited, clinical value. A complete understanding of the validity of noninvasive testing procedures in the carotid system must take into account not only their intrinsic ability to detect lesions but also the complexities of the setting in which they are applied. PMID- 6901182 TI - The role of electroencephalography in evaluating cerebrovascular disease. PMID- 6901183 TI - Computed tomography in stroke. AB - Computed tomography, an important part of the evaluation of patients with stroke, is particularly useful in distinguishing hemorrhage from infarction and in localizing lesions of the posterior fossa. A CT scan is not needed in every patient, but should be used in acute illness and when the clinical picture is not clear. PMID- 6901184 TI - Management of occlusive cerebrovascular disease. AB - Risk factors for stroke include age, hypertension, coronary artery disease, and transient ischemic attacks. The latter in particular may respond to therapy with antiplatelet agents, anticoagulants, and surgery. In patients with progressing or completed stroke, surgery carries a high risk, and medical management is favored. PMID- 6901185 TI - Hypertension and cerebrovascular disease. AB - Although hypertension is the greatest risk factor for stroke, its control with antihypertensive drugs improves survival and decreases the incidence of stroke. If a stroke should occur, careful antihypertensive therapy has not been harmful. Sodium nitroprusside is the initial drug of choice in acute crises. PMID- 6901186 TI - The surgical management of carotid artery disease. AB - A reduction in the incidence of strokes among the general population requires recognition and effective management of those who are at greatest risk for stroke. Surgical management of carotid artery disease is a valuable therapeutic approach, and is probably more effective than medical management in preventing strokes in certain patients. Not every patient is a candidate for surgery, and the surgeon must carefully weight the risks of angiography and surgery versus the risks of a stroke. Those patients at greatest surgical risk are those with significant coronary artery disease and those who are neurologically unstable. Carotid endarterectomy should only be considered if an experienced angiographer and surgeon who routinely perform this procedure with good results are available. Older patients scheduled for major surgery should be evaluated for carotid artery disease regardless of the presence of a bruit, particularly if they show evidence of atherosclerosis alsewhere. Noninvasive carotid studies are very valuable in assessing patients. With proper selection, carotid endarterectomy can decrease the incidence of the devastating stroke. PMID- 6901187 TI - Microsurgical vascular bypass for the treatment of cerebrovascular disease. PMID- 6901188 TI - Rehabilitation in cerebrovascular diseases. AB - After a stroke, the plasticity of the central nervous system usually enables some return of function, so that patients can be rehabilitated rather than simply learning to compensate for lost function. Methods for evaluating potential for rehabilitation, for the setting of realistic goals, and for functional restoration are discussed. PMID- 6901189 TI - Taste preferences of infants for sweetened or unsweetened foods. AB - This is a report of research on whether or not the addition of sugar to foods consumed by babies early in their feeding significantly alters later preference for sweetened or unsweetened foods. Twenty control babies were fed regular baby food (which already has additional sugar) for the first 3 months of their solid food feeding experience; 20 experimental babies were fed a diet with no added sugar for a similar time period. The two groups were then studied during a 4-week period in which they were randomly assigned to four different sequences of sweetened and unsweetened food. Their reactions to sweetened and unsweetened food were scored according to parental interpretation of their preferences and according to how much food they consumed. Neither group was found to prefer sweetened or unsweetened food. This finding is in contradiction of other studies and common lay and clinical views that infants prefer sweetened foods. It would seem that if babies do not prefer sweet foods, there is certainly no reason to add sugar to commercial products. PMID- 6901190 TI - Satisfaction with life for patients undergoing hemodialysis and patients suffering from osteoarthritis. AB - Two groups of chronically ill patients, alike in some respects of psychological stress and physical limitations but differing in degrees of physical threat to life because of treatment, were compared in terms of quality of life. Twenty patients undergoing hemodialysis at a satellite center and 20 patients with severe osteoarthritis receiving care at a hospital clinic, ranging in age from 40 to 60 years, were randomly selected and asked to rate themselves on Cantril's self-anchoring scale in relation to pase, present, and future life satisfaction. An ANOVA for simple main effects indicated that patients undergoing hemodialysis viewed present life satisfaction significantly higher, F = 4.81, p less than .05, than did patients with arthritis. Expectation for greater life satisfaction tended to be slightly better for dialysis patients, but not significantly so; past life satisfaction was the same for both groups. Dialysis patients viewed their present life better than past life, whereas arthritis patients had the opposite viewpoint. The increased life satisfaction among dialysis patients may be the result of an increased sense of physical well-being because of the dialysis procedure, and chronic pain may be a factor in the decreased life satisfaction among arthritis patients. PMID- 6901191 TI - Development of a social dependency scale. AB - Social dependence was defined in terms of three capacities identified as necessary for the performance of an adult role. The three capacities are everyday self-care competence, mobility competence, and social competence. Measurement of these concepts was facilitated through the use of 12 6-point scales (4 for each capacity). Scores were then computed for each capacity (range 4-24) and for all three capacities together (range 12-72). Operationally, social dependence was defined as the sum of the individual's scores in the three areas: everyday self care competence, mobility competence, and social competence. The revised instrument was tested on 60 subjects with advanced diseases to determine its reliability. The reliability coefficient alpha was .90, and the standardized-item alpha was .91. PMID- 6901193 TI - [Communication difficulties]. PMID- 6901192 TI - Elements and outcomes of a postpartum support group program. AB - Questionnaires were sent to 90 women who had participated in a lay postpartum support group program to determine (a) the characteristics of the women who used this form of support, (b) the needs met by the group, (c) the types of discussions most meaningful to group members, and (d) the factors that influenced the group's effectiveness in providing support. Sixty-six questionnaires were returned. The respondents were older, better educated, and more affluent than a random sample of childbearing women. They joined the group primarily to meet other women going through the same experience with whom they could share ideas and feelings. The most meaningful discussions for these women focused on personal issues rather than infant-related issues. The presence of babies at group meetings adversely affected the regularity of attendance. Women who worked outside the home were significantly more likely to continue meeting with the group for over a year. Only 7 women thought the group would have been better for them if their husbands had been present. PMID- 6901194 TI - [Idiopathic structural scoliosis]. PMID- 6901195 TI - [The scoliosis patient and his treatment]. PMID- 6901196 TI - [Management of pleural effusion]. PMID- 6901197 TI - [Dietetics: the nutrients]. PMID- 6901198 TI - [Care of a patient with an abdominal operation]. PMID- 6901199 TI - [Psychomotor development in children. I. The newborn infant]. PMID- 6901200 TI - [Health centers ask for the means to live]. PMID- 6901202 TI - [Blood group determination]. PMID- 6901201 TI - [Children as victims of alcohol]. PMID- 6901203 TI - [Pleural drainage]. PMID- 6901204 TI - [Reflections on theories of care. Interview by N. Wehrlin]. PMID- 6901205 TI - [Psychomotor development of the child. 2. Normal development up to 3 years of age]. PMID- 6901206 TI - [Accidents due to electricity]. PMID- 6901208 TI - [Urogenital tuberculosis]. PMID- 6901207 TI - [Tamponade: symptoms, diagnosis and treatment]. PMID- 6901209 TI - [Sterilization with ethylene oxide]. PMID- 6901210 TI - [Cranio-facial injuries]. PMID- 6901211 TI - [Professional hazard]. PMID- 6901212 TI - [Introduction of students to the pediatric service]. PMID- 6901213 TI - [Acromegaly]. PMID- 6901214 TI - [Urethral stricture: medical findings]. PMID- 6901216 TI - [Infectious mononucleosis]. PMID- 6901215 TI - [Memo on dietetics: water, minerals, vitamins]. PMID- 6901217 TI - [A new kind of hospital humanism]. PMID- 6901218 TI - [Pregnancy and environment]. PMID- 6901219 TI - [Legislation for professional personnel and surveillance of professional schools and public hospital-based schools and educational centers for paramedical professions]. PMID- 6901220 TI - [Blood group determination]. PMID- 6901221 TI - [The special role of the nurse]. PMID- 6901222 TI - [Care at home]. PMID- 6901223 TI - [Re-entry into nursing]. PMID- 6901224 TI - [Rubella]. PMID- 6901225 TI - [Urinary lithiasis]. PMID- 6901226 TI - [The prevention of surgical infections in orthopedics]. PMID- 6901227 TI - [Contraceptives]. PMID- 6901228 TI - [Functions of the supervisory nurse]. PMID- 6901230 TI - [The focus of nursing care]. PMID- 6901229 TI - [Irrigation of colostomy]. PMID- 6901231 TI - [Ulcero-necrotizing enterocolitis of newborn infants]. PMID- 6901232 TI - [Cauda equina syndrome]. PMID- 6901233 TI - [Circulating nurse in ophthalmology]. PMID- 6901236 TI - [Survey on working conditions]. PMID- 6901235 TI - [Nurses and physicians in the hospital environment]. PMID- 6901234 TI - [Vascular ulcers of the leg]. PMID- 6901237 TI - [A new period in the life of women]. PMID- 6901238 TI - Why nurses are giving it up. PMID- 6901239 TI - Confessions of a dropout. PMID- 6901240 TI - The intense nursing demands of the intra-aortic balloon pump. PMID- 6901241 TI - 'Remember. . . your're not in this alone!'. PMID- 6901242 TI - How to find hope in those 'hopeless' cases. PMID- 6901243 TI - Finding the 'therapeutic window'. PMID- 6901244 TI - Nurse/mother: how to cope with a double career. PMID- 6901245 TI - Legally speaking. Verbal orders: invitations to disaster. PMID- 6901246 TI - Nursing educators, give us a break! PMID- 6901247 TI - Sex Q & A: frank answers to your most delicate patient-counseling questions. PMID- 6901248 TI - Annual Convention educational sessions: learning and growing. PMID- 6901249 TI - Our challenges our choices. 1980 RNAO annual meeting and convention. PMID- 6901250 TI - Our challenges our choices. presidential address. PMID- 6901252 TI - [Diseases of the liver and the biliary tract. Always diagnostic and therapeutic improvements]. PMID- 6901251 TI - [Current diagnostic technics in hepato-biliary pathology]. PMID- 6901253 TI - [Surgical treatment of biliary calculi]. PMID- 6901255 TI - [The general-duty nurse: current concepts of care]. PMID- 6901254 TI - [Biliary lithiasis]. PMID- 6901257 TI - [Hygiene of food products and beverages. Preserved and semi-preserved foods]. PMID- 6901256 TI - [Perfusion solutions. Pharmacology of Dolosal (pethidine)]. PMID- 6901259 TI - [Tobacco and cardiovascular disorders]. PMID- 6901258 TI - [Diagnosis of jaundice]. PMID- 6901260 TI - [Adverse effects of tobacco on the fetus and the newborn infant]. PMID- 6901261 TI - [Anti-smoking campaign: significance of the environment]. PMID- 6901263 TI - [The nurse's role in the anti-smoking campaign]. PMID- 6901262 TI - [Is there such a thing as allergy to tobacco?]. PMID- 6901264 TI - [The hazards of tobacco]. PMID- 6901265 TI - [Food hygiene. Deep frozen products]. PMID- 6901266 TI - [The Swedish health care system. Priority for primary care, extended responsibility for nursing personnel. An experience to be emulated]. PMID- 6901267 TI - [Tobacco and the respiratory system]. PMID- 6901268 TI - [Early complications of myocardial infarction]. PMID- 6901269 TI - [Myocardial infarction: assuming technical but also psychological responsibility]. PMID- 6901270 TI - [Management of the sequelae of uncomplicated myocardial infarction]. PMID- 6901271 TI - [Prognosis of myocardial infarction from the first month onward]. PMID- 6901272 TI - [What is a myocardial infarction?]. PMID- 6901273 TI - [Myocardial infarction. Threatening syndrome]. PMID- 6901274 TI - [Nutritional risk factors in cardiovascular diseases and their prevention]. PMID- 6901275 TI - [Mr. F's myocardial infarction]. PMID- 6901276 TI - [Food hygiene. Hygiene of foodstuff and beverages: meat, poultry, cold cuts and cured products]. PMID- 6901277 TI - [The nurse and the acute period of myocardial infarction (first 24 hours)]. PMID- 6901278 TI - Fletcher factor deficiency with mildly prolonged activated PTT. PMID- 6901280 TI - Questioning: the key to learning. PMID- 6901279 TI - Nurses & stress: time to examine the potential problem. PMID- 6901281 TI - Relationship between patient behaviors and nursing staff attitudes. PMID- 6901282 TI - Research in a clinical setting: promises & potential. PMID- 6901283 TI - Management by individualization. PMID- 6901285 TI - Values: Part II. PMID- 6901284 TI - A modular approach to unit orientation. PMID- 6901286 TI - Patient care plans and the evaluation of nursing process. PMID- 6901287 TI - What nursing needs: common sense I, II, III, IV. PMID- 6901289 TI - Perspectives in nursing. Nursing managers and nursing research. PMID- 6901288 TI - Law for the nurse supervisor. Nurse's charting - Part II. PMID- 6901291 TI - Will hard times cripple nursing practice. PMID- 6901290 TI - The art & science of supervision. Professional growth. PMID- 6901292 TI - A program for caring. PMID- 6901293 TI - Values: Part III. PMID- 6901294 TI - Nurses, nursing & culture. PMID- 6901295 TI - A refresher program for RNs. PMID- 6901296 TI - Managerial role development in the nursing supervisor. PMID- 6901297 TI - Be sure they're listening. PMID- 6901300 TI - To get there--together. PMID- 6901299 TI - Law for the nurse supervisor. Nurses and the malpractice law--Part I. PMID- 6901298 TI - The art & science of supervision. Sitting in judgment. PMID- 6901301 TI - [Child abuse]. PMID- 6901302 TI - [Team work between the nurse and the speech therapist]. PMID- 6901303 TI - [Future nursing education]. PMID- 6901304 TI - [Scandinavian course in work management]. PMID- 6901305 TI - [Professorship in nursing research: milestone in the health sector]. PMID- 6901306 TI - [Researchers and research ethics]. PMID- 6901308 TI - [Cross-occupational seminar:continued education for health personnel]. PMID- 6901307 TI - [Women and research]. PMID- 6901310 TI - [Learning from patients: "De vindskeive" (You're crazy) and the hard-as-bones hospital routine]. PMID- 6901309 TI - [Patient experiences-a document for the improvement of psychiatric treatment?]. PMID- 6901311 TI - [80-year challenge to the Norwegian Nurses' Association's territories]. PMID- 6901312 TI - [Quickly, chime in with 1000 trumpets: moderation, moderation, moderation!]. PMID- 6901313 TI - [Official opening in the University of Bergen: department for nursing research a historic event]. PMID- 6901314 TI - [Pain. 1]. PMID- 6901315 TI - [Changes in midwives' education]. PMID- 6901317 TI - [Districts--a working tool for territories]. PMID- 6901316 TI - [Students and the practical examination]. PMID- 6901318 TI - [A connecting link between theory and practice in nursing]. PMID- 6901319 TI - [From a study in Bergen: working with the elderly; hard but pleasant]. PMID- 6901320 TI - [Home nursing in Ostfold: a functional study based on statements and answers by the nurse administrator]. PMID- 6901321 TI - [A word at the right time: Florence Nightingale is dead]. PMID- 6901322 TI - [Focus on nursing 80: do we have need for the clinical nurse specialist?]. PMID- 6901323 TI - [Nursing - an obvious choice for university studies]. PMID- 6901324 TI - [Promise of confidentiality - and the need for someone to confide in]. PMID- 6901325 TI - [Norwegian Nurses' Association's central organs]. PMID- 6901326 TI - [Hospital infections and Scandinavian team work]. PMID- 6901328 TI - [Cultural heritage and health]. PMID- 6901327 TI - [Health nurses' home visit to families with newborn infants]. PMID- 6901329 TI - [EDP in the hospital--an aid or a nuisance?]. PMID- 6901330 TI - [What do nurses do in case of fire?]. PMID- 6901332 TI - [Induced abortion: free abortion freedom for whom? We meet the patients once the decision for abortion has been made]. PMID- 6901331 TI - [Circumcision of women in developing countries]. PMID- 6901333 TI - [An extra week in case of the smallest doubt]. PMID- 6901334 TI - [The patient's life is the physician's responsibility]. PMID- 6901335 TI - [How can the effect of pain treatment in terminal oncology patients be measured: only patients can tell us what pain is like]. PMID- 6901336 TI - [Seminar on early parent-infant attachment in the Panum Institute, 18-19 January: childbirth means a challenge to the nurse]. PMID- 6901337 TI - [Rubella prevention in personnel of Funen's county hospital: 10-20 percent of fertile women can contract German measles]. PMID- 6901338 TI - [Primary health services. 3. Residents of nursing homes are our equals]. PMID- 6901339 TI - [The nurse and research in nursing]. PMID- 6901340 TI - [Thoughts behind a facade]. PMID- 6901341 TI - [Hospices: an alternative for those who want to die at home]. PMID- 6901342 TI - [Experiences from an isolation ward for children. Physical isolation should not become psychological isolation]. PMID- 6901343 TI - [Primary health services. 4. Countless physical and psychological wounds are treated]. PMID- 6901346 TI - [Developments in office nursing activities: working in an office is an occupation in itself]. PMID- 6901345 TI - [We need criticism]. PMID- 6901344 TI - [Qualified nursing care needs qualified observation]. PMID- 6901347 TI - [Trade Security Council for social and health care system: could prove important for environmental safety activities]. PMID- 6901348 TI - [Executive meeting 11-12 March: should nurses withdraw from the field of services for mentally retarded?]. PMID- 6901349 TI - [We think we take the child's sexuality for granted]. PMID- 6901350 TI - [Nursing education and the EEC-system]. PMID- 6901351 TI - [Team work between the community health nurse and the general practitioner: support each other in catching children's smallest signals]. PMID- 6901353 TI - [Research in nursing: knowledge and technology based on testing and supporting theory]. PMID- 6901352 TI - [Care and treatment of chronic pain in malignant diseases: when pain is removed the need for medication can be lessened]. PMID- 6901354 TI - [Dying is not a failure]. PMID- 6901355 TI - [How, when, why?]. PMID- 6901356 TI - [Parallel action to survive as a group within the nursing home sector]. PMID- 6901357 TI - [Request for the use of employment measures in nursing education]. PMID- 6901358 TI - [Interaction with patients--an important link in psychological nursing: psychological nursing can recreate nurses' professional identity]. PMID- 6901359 TI - [What has changed in radiography?]. PMID- 6901360 TI - [Minister of Finances Svend Jakobsen: we have an economic and political crisis at the same time. Interview by Peter Hjorth]. PMID- 6901361 TI - [Ethical question in nursing: heart arrest, a matter of more than only life and death]. PMID- 6901363 TI - Can touch make a difference in nursing care? An experimental study. PMID- 6901364 TI - [The nurse and responsibility for the property of patients]. PMID- 6901362 TI - [State of the kallikrein-kinin, blood coagulation and fibrinolytic systems of blood in various forms of influenza]. PMID- 6901365 TI - [Management, organization and personnel shortage in nursing homes and psychiatric hospitals]. PMID- 6901366 TI - [Parent-child relationship during pregnancy and puerperium: an aspect of medical and nursing care]. PMID- 6901367 TI - [Guidance of student nurses during the practical learning period. II]. PMID- 6901368 TI - [EEC Information Center. Information concerning employment in member countries of the European Economic Community: Belgium, Denmark, German Federal Republic, France, Italy, Luxembourg, Ireland, the United Kingdom (England, Scotland, Northern Ireland)]. PMID- 6901369 TI - [A new urimeter with an overflow reservoir and suitable for taking urine specimens]. PMID- 6901370 TI - ['Professional worker-voluntary worker, or human aspects in assistance'. Additional observations in the utilization of voluntary workers]. PMID- 6901371 TI - [Activities for additional nursing personnel: contribution for discussion]. PMID- 6901372 TI - [Reactions of parents with a schistasis child]. PMID- 6901373 TI - [Guidance of student nurses during the practical learning period. III]. PMID- 6901374 TI - [Various aspects in the distribution of medications]. PMID- 6901375 TI - [National Work Group Nurse-Anesthetists. Contribution by the National Work Group to the study day by and for nurse-anesthetists]. PMID- 6901376 TI - [Current residential conditions for psychiatric patients]. PMID- 6901378 TI - [This is how a patient can feel... spinal anesthesia. II]. PMID- 6901377 TI - [Experience report of a working period in psychogeriatrics. I]. PMID- 6901379 TI - [Integrated approach: the patient with cystic fibrosis. Medical aspects]. PMID- 6901381 TI - [Patients with cystic fibrosis. Nutrition]. PMID- 6901380 TI - [Integrated approach: the patient with cystic fibrosis. Physiotherapeutic treatment]. PMID- 6901382 TI - [Integrated approach: the family of a patient with cystic fibrosis]. PMID- 6901383 TI - [Patients with cystic fibrosis: observation and guidance]. PMID- 6901384 TI - [Patients with cystic fibrosis: nursing care of children with cystic fibrosis]. PMID- 6901385 TI - [Thinking about death--a personal experience]. PMID- 6901386 TI - [Experience report of a working period in psychogeriatrics. II]. PMID- 6901387 TI - [The administrative structure of hospitals in perspective]. PMID- 6901388 TI - [Promotion of expertise of nurses]. PMID- 6901390 TI - [Children on radiotherapy]. PMID- 6901389 TI - [Sex when you have diabetes mellitus]. PMID- 6901391 TI - [Professional worker - voluntary worker, or human aspects in assistance]. PMID- 6901392 TI - [Reading difficulties in aging]. PMID- 6901393 TI - [Effective personnel staffing: contribution for discussion]. PMID- 6901395 TI - [Legislative proposal on admission to psychiatric hospitals is published]. PMID- 6901394 TI - [Guidance of graduates of the Intermediate Professional Nursing Education programs in a general hospital]. PMID- 6901396 TI - [Nursing aspects in incontinence problems]. PMID- 6901397 TI - [Intermittend (self) catheterization in urination disorders]. PMID- 6901398 TI - [The ombudsman's function in Welterhof in relation to national development]. PMID- 6901400 TI - [The final oral evaluation in the education of A-nursing: memo from the National Professional Organization of Health Services' Employees]. PMID- 6901399 TI - [School nurses in child health care]. PMID- 6901401 TI - [O.R. nurses]. PMID- 6901403 TI - [The family in the postnatal period: psychosocial aspects of medical and nursing care]. PMID- 6901402 TI - [Sensory development - really something for the severely retarded]. PMID- 6901404 TI - [Febrile convulsions. I]. PMID- 6901405 TI - [An American professor on: university education in nursing sciences in Maastricht. Plea for a growth model]. PMID- 6901406 TI - [5 cases: homosexuality and health care]. PMID- 6901408 TI - [Guidance of graduates of the Intermediate Professional Nursing Education program in a general hospital]. PMID- 6901407 TI - [The Intermediate Community Nursing Education as continuation education after the Intermediate Professional Nursing Education (?)]. PMID- 6901409 TI - Profile: Kathleen A. Lamb, RN, BSN, MSN. Interview by Diana S. Wheeler. PMID- 6901410 TI - OR symposium: Part I. PMID- 6901412 TI - Pain management. Foreword. PMID- 6901411 TI - Pain management. PMID- 6901413 TI - Holistic management of chronic pain. PMID- 6901414 TI - The effects of preoperative teaching on postoperative pain. PMID- 6901415 TI - Pain theories: an overview. PMID- 6901416 TI - Education for self-care. Foreword. PMID- 6901418 TI - Health promotion/self-care programs for the community. PMID- 6901419 TI - A fourth-grade adventure in self-directed learning. PMID- 6901417 TI - Patient counseling vs. patient teaching. PMID- 6901420 TI - Consumers learn to monitor their own health. PMID- 6901421 TI - Health education from a group perspective. PMID- 6901422 TI - Utilizing Orem's self-care nursing model in designing an educational program for the diabetic. PMID- 6901423 TI - Group meetings for families of burn victims. PMID- 6901424 TI - Selecting media for patient education. PMID- 6901425 TI - Seize the moment: health promotion for the young adult. PMID- 6901429 TI - Urology--1: renal physiology. PMID- 6901427 TI - [Blood plasma kallikrein-kinin system in acute intestinal obstruction with the experimental use of hyperbaric oxygenation]. AB - The model of acute mechanical ileus was created in 130 albino rats. Components of the blood kinin system were investigated. During the second day the kinin system of blood was activated, during the third day it was depleted. The use of one performance of HBO on the 2nd and 3d day of ileus decreased the level of kinin forming factors. The investigations performed create prerequisites for using HBO and antikinin drugs in the postoperative period of acute ileus, control of the kinin system parameters being strictly observed. PMID- 6901426 TI - [Effects of vitamin A on formation of aminoacyl-tRNA]. AB - The melting temperature and hyperchromia of intestine mucosa tRNA preparations and the effect of inactivating factors on aminoacyl-tRNA-synthetase activity were studied at the stage of hypovitaminosis and under deep A-avitaminosis. It is shown that in the aminoacylation reaction, aminoacyl-tRNA-synthetase is a component more sensitive to vitamin A deficiency. PMID- 6901428 TI - Xylazine/sodium thiopental combination for short-term anesthesia in the horse. PMID- 6901430 TI - Nebulization therapy in cage-bird medicine. PMID- 6901431 TI - How to handle puppies during inoculations. PMID- 6901433 TI - Survey of heartworm disease (Dirofilaria immitis) in the Kanawha Valley, West Virginia. PMID- 6901432 TI - Lipemia retinalis associated with pancreatitis in a dog (a case report). PMID- 6901434 TI - Electrocardiology of the anesthetized patient--1: interpretation of the ECG. PMID- 6901435 TI - Fibrocartilaginous infarct in a German Shepherd dog. PMID- 6901436 TI - Predation of lambs. PMID- 6901437 TI - Diagnostic and prognostic considerations related to exploratory laparorumenotomy in the bovine species. PMID- 6901438 TI - The influence of certain medicants on fecal bacteria of calves. PMID- 6901439 TI - High morbidity pneumonia in dairy calves in Ohio (a case report). PMID- 6901440 TI - Bovine estrus synchronization: making the most of a new opportunity. Part 1: A preparation guide for practitioners. PMID- 6901441 TI - Styphlodora horrida in the kidneys and ureters of a boa constrictor (Constrictor constrictor). PMID- 6901442 TI - Gastrotomy in a gulf hammock rat snake (Elaphe obsoleta williamsi). PMID- 6901443 TI - A description of helminths in a kit fox (Vulpes macrotis). PMID- 6901444 TI - Tax-wise: tidbits of tax savvy that could save you money. PMID- 6901446 TI - Nursing: decision not chance. PMID- 6901445 TI - A tough act to follow--success. PMID- 6901447 TI - The pain clinic: a multidisciplinary approach to long term pain. PMID- 6901448 TI - Nursing in the world of wellness. PMID- 6901449 TI - Marketing yourself and your program. PMID- 6901450 TI - A case report of basal cell adenoma showing elastic fiber (elastin-basement membrane complex) formation of the submandibular gland. AB - A biopsy case of basal cell adenoma of the submandibular gland was reported in a 15-year-old boy. The tumor was pigeon's egg-sized, spherical in shape and encapsulated by fibrous tissue, and its cut-surface was grayish white. Histologic feature of this neoplasm was a trabecular or tubular monomorphic adenoma with well-developed elastic fibers (elastin-basement membrane complex) in the interstitial tissue. Electron microscopy disclosed 4 kinds of tumor cells, that is, secreting cells, squamous cell-like cells with tonofibrils and tonofilaments, clear cells with a few filaments, and myoepithelial cells. The interstitium contained elastin, collagen fibrils and basement membrane-like substance. Possible production of elastic fibers by the myoepithelial cells of this adenoma was discussed. PMID- 6901451 TI - AACN survey shows faculty salaries up. PMID- 6901452 TI - MNA reports first in-depth analysis of nursing in state. PMID- 6901453 TI - Continuous transcutaneous O2 monitoring in the neonate. PMID- 6901454 TI - Give the older person space. PMID- 6901455 TI - Scalp tourniquets for chemotherapy-induced alopecia. PMID- 6901457 TI - Be prepared for camp nursing. PMID- 6901458 TI - TMJ syndrome. PMID- 6901456 TI - Alopecia and chemotherapy. PMID- 6901459 TI - Stress: type A behavior in the nurse. PMID- 6901460 TI - Stress: never jump out of a perfectly good airplane. PMID- 6901461 TI - Caring for the patient with a primary retinal detachment. PMID- 6901462 TI - How to assess the nutritional status of acutely ill patients. PMID- 6901463 TI - Hypertension: common questions patients ask. PMID- 6901464 TI - Hypertension: what it does to the body. PMID- 6901466 TI - Hypertension: what can go wrong when you measure blood pressure. PMID- 6901465 TI - Hypertension: how therapy works. PMID- 6901467 TI - Privileged communication. PMID- 6901468 TI - Campaigning for health programs. PMID- 6901469 TI - Why are we on strike? PMID- 6901470 TI - Living with thyrotoxicosis. PMID- 6901471 TI - No inherent increase in efficiency of scintillation counting for 3H-labeled amino acids bound to transfer RNA. PMID- 6901472 TI - Is nursing a segregated profession? Two views: a day with EEOC and a day in court. PMID- 6901473 TI - As I see it... what can nursing do to control costs? PMID- 6901474 TI - 'Women hold up half the sky'. PMID- 6901475 TI - Antibiotic-resistant Staphylococcus epidermidis in patients undergoing cardiac surgery. AB - Staphylococcus epidermidis isolates containing subpopulations resistant to 100 microgram of methicillin per ml were found on the chests of only 3 of 80 (4%) patients before cardiac surgery, whereas these highly resistant staphylococci were isolated from the chest wounds of 43 of 80 (54%) patients 5 days postoperatively. The percentage of patients colonized with methicillin-resistant S. epidermidis increased with time postoperatively. Methicillin-resistant postoperative isolates also contained organisms resistant to other antibiotics frequently used during these patients' hospitalizations. The percentages of patients with organisms resistant to various antibiotics were: nafcillin (100%), penicillin (100%), cephalothin (93%), cefamandole (80%), streptomycin (67%), and gentamicin (20%). Preoperative methicillin-susceptible isolates were generally susceptible to other antibiotics. Two patients with S. epidermidis prosthetic valve endocariditis caused by multiple antibiotic-resistant isolates were among the study patients. Antibiotic susceptibility patterns of each isolate from these two patients were identical to those of postoperative chest isolates from the same patient. PMID- 6901476 TI - Educational preparation of clinical nurse specialists in rehabilitation nursing. PMID- 6901477 TI - Programmed instruction: functioning of the normal and neurogenic bladder. PMID- 6901478 TI - Rehabilitation Nursing Institute. PMID- 6901480 TI - Time to go. PMID- 6901481 TI - International nursing: O.R.S. formula urged for control of diarrhoeal diseases. PMID- 6901479 TI - Application of Bobath principles for nursing care of the hemiplegic patient. PMID- 6901482 TI - Levodopa-carbidopa. PMID- 6901483 TI - Family centred community nursing: the Bethlehem MS service. PMID- 6901484 TI - Nursing: profession or pretender? PMID- 6901485 TI - Nursing diagnosis (assessment) and changing accountability. PMID- 6901486 TI - Thoughts of an early-morning clinic Sister. PMID- 6901487 TI - Mandatory continuing education: will it raise the standard of nursing practice? PMID- 6901488 TI - The curriculum and the new graduate in a community service. PMID- 6901489 TI - It's not a sinecure I can assure you. PMID- 6901490 TI - Primary nursing at Concord (R.G.H.):--it really does work. PMID- 6901491 TI - Victorian project explores nature of community nursing. PMID- 6901492 TI - Victoria looks at on-going education. PMID- 6901493 TI - This is my life. PMID- 6901494 TI - Observations on the use of a quality monitoring instrument. PMID- 6901495 TI - Primary nursing: Australia's emerging patterns. PMID- 6901497 TI - Post-basic nursing education at WAIT. PMID- 6901496 TI - The nurse administrator's role in the 1980's. PMID- 6901498 TI - The effectiveness of registered nurses in breast self examination. PMID- 6901499 TI - Family planning in urban Aboriginal and Islander communities. Part II. PMID- 6901500 TI - The potential political power of nursing. PMID- 6901501 TI - Games people play. PMID- 6901502 TI - The registered nurse and aid in emergency. PMID- 6901504 TI - [Irrigation and instillation]. PMID- 6901503 TI - [In psychiatry: care and quality of life]. PMID- 6901505 TI - Binding of terbium to porcine pancreatic elastase. Ligand-induced changes in the stability, the maximum luminescence intensity, and the circularly polarized luminescence spectrum of the complex. PMID- 6901506 TI - The role of eIF-4C in protein synthesis initiation complex formation. AB - eIF-4C has a pronounced stimulatory effect on initiation complex formation with native 80-S ribosomes (80-Sn) as the only source of ribosomal subunits, but only a small effect when washed 40-S subunits are used. eIF-4C is accessary to eIF-3 in dissociating 80-Sn ribosomes. eIF-4C is present on 40-Sn but absent on 40-Sn dimers, which occur in preparations of native ribosomes and are as such inactive in protein synthesis. eIF-4C dissociates 40-Sn dimers into active monomers. These results can be explained by assuming that the presence of eIF-4C on 40-Sn prevents: (a) premature association with 60-S ribosomal subunits and (b) dimerisation, thus increasing the rate and extent of initiation complex formation. PMID- 6901507 TI - The major fibrinolytic proteases of human leukocytes. AB - The major fibrinolytic enzymes present in leukocyte granules and active at physiological pH have been identified. The fibrinolytic activity in extracts of leukocyte granules was found to fibrinogen-Sepharose and eluted with 8.0 M urea. Two distinct zones of fibrinolytic activity were detected upon electrophoresis of leukocyte extracts on fibrinogen polyacrylamide gels, and both were qualitatively recovered in the 8.0 M urea eluate. Quantitatively, greater than 95% of the fibrinolytic activity was recovered in the urea eluate. Two major leukocyte proteases, elastase (EC 3.4.21.11) and cathepsin G (EC 3.4.21.-), were quantitatively recovered in the urea eluate. Both enzymes, when purified separately by affinity chromatography, were shown to: (a) possess fibrinolytic activity; (b) coincide in mobility and generate the two zones of fibrinolytic activity on fibrinogen polyacrylamide gels; and (c) quantitatively reconstitute the fibrinolytic activity of the leukocyte granules when combined at activity levels present in granular extracts. A highly significant correlation (r = 0.98) was found between the fibrinolytic activity and the sum of elastase and cathepsin G activity in leukocytes from five donors. Thus, elastase and cathepsin G are the major enzymes of the leukocyte fibrinolytic pathway, and fibrinogen-Sepharose chromatography may be used to obtain these enzymes. PMID- 6901508 TI - Human monocyte spreading induced by factor B of the alternative pathway of complement activation. PMID- 6901509 TI - Cardiac auscultation. PMID- 6901510 TI - Soluble factors and increase of protein synthesis in regenerating liver. PMID- 6901511 TI - [Is chronic schizophrenia an artefact?--Arguments and counter-arguments (author's transl)]. AB - The working hypothesis is investigated that chronic schizophrenia could differ from acute schizophrenia not only phenomenologically, but also in its causes. The following arguments in favour of the hypothesis that chronic schizophrenia could mainly be a psychosocial "artefact", caused by the psycho-social consequences of acute attacks of illness, are presented 1. institutionalisme and understimulation; 2. non-specifity of many phenomenons attributed to "chronic schizophrenia"; 3. great variability of long-term courses; 4. lack of influence of genetic factors on long-term course; 5. importance of social factors for long term course; proposition of a "general principle of psychosocial inertia"; 6. family influences; 7. lack of sufficient proofs for a clearcut illness-concept. - On the other hand the following arguments against the artefact-hypothesis are discussed: 1. the question of "irreversible residual states"; 2. organic and biochemical arguments; 3. genetic arguments; 4. the problematic distinction between acute and chronic schizophrenia; 5. the ubiquity of chronic schizophrenia. --On the whole, the arguments in favour of the artefact-hypothesis seem more pertinent, but more research is needed for a definite decision. PMID- 6901513 TI - [Clinical significance of blood level-determinations of antiepileptic drugs (author's transl)]. PMID- 6901512 TI - [The Kleine-Levin-Critchley-syndrome. A contribution to the solution of differential diagnosis (author's transl)]. AB - The typical symptoms of the so-called Kleine-Levin-Critchley-Syndrome are described according to our own observation of four selected patients (one woman, three men) on the background of the literature on the subject. In contrast to the first descriptions we characterise this syndrome by the Trias: periodic hypersomnia, vegetative disturbances (especially of food intake) and psychopathologic symptoms. Especially young men in their second decade of life suffer from this syndrome. As far as women are concerned the disease is found more seldom but the authors are sure that it exists. A spontaneous remission of the periodically proceeding disease often occurs in the third decade of life. In analogy to the respective literature a retardation of the EEG during the course of the disease going along with otherwise inconspicuous neurology was observed by the authors. Polygraphic-EEG studies are seldom. The cause of the syndrome is still open to question. Our observation show that a primarily disposition-linked and a secondarily acquisition-linked form can be assumed. Good effects are put down to amphetamines used for therapy. As far as differential diagnosis is concerned infections and abusus must be excluded. PMID- 6901514 TI - Properdin factor B (Bf) as an exclusion determinate in parentage testing. AB - Properdin factor B (Bf) was phenotyped on 519 paternity cases. Gene frequencies of BfF = 0.1870, BfF1 = 0.0105, BfS = 0.7985 and BfSO.7 = 0.0040 were observed in Minnesota Whites. Based on these values the exclusion probability is (p) = 0.1442. Bf accounted for 15% of the 88 observed exclusions. A technique is described for simultaneous electrophoresis of Bf and Gc on the same gel. PMID- 6901515 TI - A comparative analysis of human IgM rheumatoid factor degradation by purified elastase and total granule extracts from human polymorphonuclear leukocytes. AB - A modified digestion system using radiolabeled IgM rheumatoid factors (RF) and unlabeled IgG was used to examine IgM RF digestion by human polymorphonuclear leukocyte (PMN) elastase. Upon molecular sieve chromatography, the radioactive fragments coelute with fragments produced by elastase digestion of an IgM protein giving no RF activity. The fragments represent an Fab2-like fragment, an Fab-like fragment, and small peptides. Utilizing this same system, digests were performed at both acid and neutral pH to compare the proteolytic action of purified elastase on IgM RF (Ove) to the action of the total granule extract (TGE) from human PMN. At pH 4.5, purified elastase exhibits low-level protease activity, producing a slightly degraded IgM fragment with a molecular weight of about 800,000 daltons. In contrast, TGE at pH 4.5 completely degrades IgM RF to small peptides. At pH 7.5, the fragments produced by TGE digestion of IgM (Ove) coelute with fragments produced by elastase digestion under the same conditions. Thus elastase appears to be the major granule protease active in IgM RF degradation at the pH characterizing the inflammatory site. PMID- 6901517 TI - The "most wanted" list. PMID- 6901516 TI - Rabbit prekallikrein. Purification, biochemical characterization, and mechanism of activation. AB - Rabbit prekallikrein (RPK) was purified from rabbit plasma by ion exchange and lectin column chromatography and preparative polyacrylamide gel electrophoresis. A 1500-fold purification was routinely achieved with a final yield of 5-10%. The purified RPK was found to be a glycoprotein with an apparent molecular weight of 88,000. Activation of RPK with either trypsin or rabbit Hageman factor (active) occurs by limited proteolytic cleavage, producing two disulfide-linked polypeptide chains with molecular weights of 55,000 and 35,000. Both chains contain carbohyrate and the 35,000-molecular-weight polypeptide was shown to incorporate [3H]DFP. Activation of RPK in kaolin-treated plasma was shown to proceed by an analogous mechanism yielding 55,000- and 35,000-molecular-weight polypeptide chains. PMID- 6901518 TI - The correlation between sleep deprivation and the intensive care unit syndrome. PMID- 6901519 TI - Adverse effects of disopyramide (Norpace): toxic interactions with other antiarrhythmic agents. PMID- 6901520 TI - Clinical pharmacology of the antiarrhythmic agent disopyramide phosphate (Norpace). PMID- 6901521 TI - Stress effects on patients in critical care units from procedures performed on others. PMID- 6901522 TI - Hypertensive patients' understanding of terminology. PMID- 6901523 TI - Boerhaave's syndrome: a rare disease with some not so rare implications for nursing care. PMID- 6901524 TI - Multiple pulmonary abscesses resulting from pulmonary mucormycosis. PMID- 6901525 TI - Initiation of the diving reflex in neonates with supraventricular tachycardia. PMID- 6901526 TI - A case of Prinzmetal's angina with right bundle branch block. PMID- 6901527 TI - Chronic meningitis-benign and malignant forms. PMID- 6901528 TI - Hemodynamic monitoring in the coronary care unit. PMID- 6901530 TI - Human high molecular weight kininogen. Effects of cleavage by kallikrein on protein structure and procoagulant activity. PMID- 6901529 TI - A new fluorogenic substrate method for the estimation of kallikrein in urine. AB - Kallikrein in human urine was measured using a fluorogenic peptide substrate, proly-phenyl-alanyl-arginine-4-methylcoumaryl-7-amide (Pro-Phe-Arg-MCA). Using 20 microliters of normal urine, kallikrein activity was quantitatively assayed by incubation with a final concentration of 10(-4) M Pro-Phe-Arg-MCA at 37 degrees C for 90 min. The reaction was terminated by adding 50 units of Trasylolr or 20 microliters of 10% acetic acid. Using this method, kallikrein activity was measured in urine from normal subjects and patients with glomerulonephitis and Bartter's syndrome. These values were comparable with the values obtained by radioimmunoassay using bovine low-molecular-weight kininogen. When normal urine was applied to a column of arginine-Sepharose 4B, two activities, Pro-Phe-Arg-MCA hydrolyzing activity and kinin-releasing activity toward bovine low-molecular weight kininogen, were eluted in the same fraction. These results indicate that the present method is useful for the estimation of kallikrein in urine, in terms of specificity, sensitivity, and simplicity. PMID- 6901531 TI - Protein synthesis in rabbit reticulocytes. Preparation of homogeneous Met-tRNAf deacylase and studies of its role in protein synthesis. AB - Met-tRNAf deacylase from reticulocyte ribosomes has been purified to homogeneity. Upon sodium dodecyl sulfate-polyacrylamide gel electrophoresis, the homogeneous preparation gives a single protein band corresponding to a molecular weight of approximately 67,000. Purified Met-tRNAf deacylase degrades free Met-tRNAf and also Met-tRNAf bound to 40 S ribosomes in the presence of AUG codon but does not degrade Met-tRNAf in the ternary complex, Met-tRNAf.eIF-2.GTP. Purified Met-tRNAf deacylase does not inhibit protein synthesis in reticulocyte lysates at any concentration tested indicating that Met-tRNAf deacylase is not a protein synthesis inhibitor. Antibodies against Met-tRNAf deacylase have been prepared by immunizing a chicken with homogeneous preparation of Met-tRNAf deacylase. Addition of anti-Met-tRNAf deacylase does not have any effect on protein synthesis in reticulocyte lysates indicating that Met-tRNAf deacylase is not required for protein synthesis. PMID- 6901533 TI - [Physiology and pathology of the pancreatic kallikrein-kinin system]. PMID- 6901532 TI - Cultured animal cells exposed to amino acid analogues or puromycin rapidly synthesize several polypeptides. AB - Four major acidic polypeptides, with molecular weights of 88, 72, 71, and 23 thousand, and minor polypeptides with molecular weights of 110, 50, 38, and 30 thousand rapidly accumulated in cultured chick embryo (CE) cells which were exposed for three hours to the arginine analogue canavanine. P110, P88, P71,72, and P23 had unique peptide maps. Evidence of a 27,000 dalton precursor to P23 was obtained. The analogue-stimulated proteins were not related to another set of inducible avian polypeptides known as the glucose-regulated proteins. In mammalian cells, the rate of accumulation of several polypeptides, which were similar in size to the avian proteins, sharply increased after canavanine treatment. Proteins with the same electrophoretic mobilities, isoelectric points, and peptide maps as the analogue-stimulated proteins were expressed at low levels in untreated cultures. To determine the time courses of the canavanine-mediated increases in protein accumulation and the recovery of protein metabolism after analogue treatment, radioactively labeled proteins were extracted from CE cells and analyzed on SDS-polyacrylamide gels. In cultures exposed to canavanine, the rates of accumulation of P88 and P71,72 increased from basal to new plateau levels in about 1.5 hours, while P23 required about 2.5 hours. When added with the analogue, actinomycin D and cordycepin blocked the increases in protein accumulation. These inhibitors also blocked the rapid decline in the rates of accumulation of the enhanced proteins which occurred after removal of canavanine. Studies of the matabolic stability of the enhanced proteins indicated that the changes in their accumulation were caused by alterations in their rates of synthesis. Thus, the analogue-mediated response fulfilled several of the criteria for inducible eucaryotic gene expression. The amino acid analogue p fluorophenylalanine and the chain-terminating analogue of amino acyl-tRNA puromycin stimulated the synthesis of the same set of proteins induced by canavanine. The enhanced synthesis of these proteins appeared to be a cellular response to either the presence or catabolism of abnormal proteins and puromycyl peptides. PMID- 6901534 TI - The effect of chronic childhood illnesses upon well siblings. PMID- 6901535 TI - Anal compulsive behaviors of one four-and-a-half year old hospitalized boy. PMID- 6901536 TI - Body image concerns of a four year old boy with meningitis. PMID- 6901537 TI - Conceptual framework for nursing practice. PMID- 6901538 TI - Mothers' perceptions of their labor experiences. PMID- 6901539 TI - Parents' and childrens' reactions toward impending hospitalization for surgery. PMID- 6901540 TI - Effect of maternal expectations and child-rearing practices on the development of white and Puerto Rican children. PMID- 6901541 TI - [Effect of kallikrein in chronic post-apoplectic cerebral infarct]. PMID- 6901542 TI - [Histomorphometric studies on the effect of the kallikrein-kinin system on fracture healing in rats]. PMID- 6901543 TI - Properdin factor B and glyoxalase 1 polymorphism in celiac disease. PMID- 6901545 TI - Measuring identification with the mothering role. AB - Three summated rating scales entitled Feelings of Motherliness (FOM), Conception of the Fetus as a Person (CFP), and Appropriateness of Fantasies about the Baby to be (AFB) were constructed. During instrument development, data were collected from a sample of 169 women selected using the criteria of gravidity, ethnicity, and experience. Thirty-four of these women were used to test the final versions of the scales. Coefficient alphas for FOM, CFP, and AFB were.87, .89, and .67, respectively. Coefficient alphas for the subscales ranged from .88 to 1.0. Content validity was built into the scales. The data supported the concept validity of FOM and CFP, but not AFB. Three subscales of the Parental Attitude Research Instrument were used as criterion measures; criterion validity was not established. Construct validity was assessed using convergent and discriminant measures. Data provided support for convergent validity, but not for discriminant validity. Further modification and testing of the scales are needed. PMID- 6901546 TI - Comparative analysis of nonverbal interpersonal communication of schizophrenics and normals. AB - The nonverbal communications of schizophrenics and normals in dyadic interactions were analyzed and compared. Twelve purposively selected women were videotaped in normal-normal, normal-schizophrenic, and schizophrenic-schizophrenic communication acts for 30 minutes. Using a PLATO IV computer program and a modified Kendon Kinesic Notation System, a priori sets of nonverbal behaviors were recorded at 1-second intervals. Frequency and duration scores for the sets of nonverbal behaviors with corresponding communication meanings were totaled. A nested analysis of variance showed that the three groups differed significantly (p less than .05) in engagement and defensiveness and that the normal interactors were the least imitative of the three groups. An analysis and description of the patterns of nonverbal communication also revealed differences, lending support to the theory of dysjunctive schizophrenic communication. PMID- 6901547 TI - A critique of several conceptions of practice theory in nursing. AB - The thesis of this article is that the Dickoff, James, and Wiedenbach (1968a, 1968b) conception of a practice theory is roughly equivalent to a plan of action. This idea is contrasted with other conceptions of a prescriptive practice theory, especially the set-of-rules conception described by Jacox (1974). The set-of rules conception is shown to be untenable, and other conceptions of practice theory are shown to be nothing more than examples of established forms of knowledge. PMID- 6901548 TI - Life events, emotional support, and health of older people. AB - The effects of life events, emotional support, interaction of life events and emotional support, and age on indices of physical and psychological health were examined within a hierarchical multiple-regression design. Fifty older people who were randomly selected from among the residents of a high-rise apartment building provided retrospective data on their life events and emotional support. These same subjects provided more recent data on their functional health, distress arising from chronic health problems, and four indices of morale (agitation, attitude toward own aging, lonely dissatisfaction, and a combined index of the morale dimensions). As expected, significant multivariate effects were demonstrated on all but two measures: distress arising from chronic health problems and attitude toward aging. Examination of the independent contributions to these effects showed variations depending on the health index of focus. Expected moderations of the effects of life events by emotional support effects were not demonstrated. Results are discussed in relationship to previous research and the theoretical expectation that emotional support would moderate the effects of life events on health. PMID- 6901549 TI - The clinical pathology laboratory--7. Preparation of the luekocytic hemogram. PMID- 6901550 TI - Those annoying changes in the names of microbes. PMID- 6901544 TI - Ribosomal function and its inhibition by antibiotics in prokaryotes. AB - Most of the known antibiotics act at the level of protein biosynthesis probably due to the extraordinary complexity of the translation machinery which can be interfered with at many points. At first a survey is given of our present knowledge covering the structure and function of the prokaryotic ribosome. The most important antibiotics acting at the translational level are integrated into this network of data. The binding sites and the inhibition mechanisms of the drugs, together with the ribosomal components altered in resistant mutants are described. Finally, the points of interference with the translational machinery are indicated in an extended scheme of ribosomal functions. PMID- 6901551 TI - Curtailing canine activity for medical purposes. PMID- 6901552 TI - Paratracheal mediastinotomy in the dog and cat. PMID- 6901553 TI - Gastric foreign body in a dog: case report and discussion of radiographic principles. PMID- 6901554 TI - Aortic thromboembolism in a cat. PMID- 6901555 TI - Clostridium chauvoei as the cause of malignant edema in a horse. PMID- 6901556 TI - Differential diagnosis of caseous lymphadenitis in the goat. PMID- 6901557 TI - Field use of xylazine in cattle. PMID- 6901558 TI - Food-animal regional anesthesia. Bovine blocks: continuous epidural anesthesia. PMID- 6901559 TI - Pediculosis and severe heartworm infection in a harbor seal. PMID- 6901560 TI - [Components of the blood and kidney kinin system in diabetes mellitus with the signs of myocardiodystrophy]. PMID- 6901561 TI - Equal calcitonin response in paretic and non-paretic cows after intravenous calcium infusion. PMID- 6901562 TI - Art and a dying patient. PMID- 6901563 TI - Incidents--need they be accidents? PMID- 6901564 TI - Letter to Jo. PMID- 6901566 TI - Working through recovery after mastectomy. PMID- 6901565 TI - Unification: bringing nursing service and nursing education together. PMID- 6901567 TI - Treatment of pressure ulcers. PMID- 6901568 TI - Nurse management of hypertension. PMID- 6901569 TI - Nursing vs. nonnursing administration preparation. PMID- 6901570 TI - Nursing staff bylaws. PMID- 6901571 TI - Programmed instruction: pulmonary function tests in patient care. PMID- 6901572 TI - Shoes. PMID- 6901573 TI - When in doubt--speak out. PMID- 6901574 TI - "... In support of circumcision...". PMID- 6901575 TI - Cerebral artery bypass surgery. PMID- 6901576 TI - Antiarrhythmic drug therapy. PMID- 6901577 TI - Finding your leadership style in groups. PMID- 6901578 TI - Congenital adrenocortical hyperplasia: a boy with CAH. PMID- 6901579 TI - Congenital adrenocortical hyperplasia: the syndrome. PMID- 6901580 TI - Congenital adrenocortical hyperplasia: nursing interactions. PMID- 6901581 TI - Diabetes assessment guide. PMID- 6901582 TI - The nurses' health study: current findings. PMID- 6901583 TI - New approach to measuring adult nasogastric tubes for insertion. PMID- 6901584 TI - Amyloidosis-a deadly disease. PMID- 6901585 TI - Are enemas justified for women in labor? PMID- 6901586 TI - Does patient contact change racial perceptions? PMID- 6901587 TI - Electrical safety in the hospital. PMID- 6901588 TI - Competing ethical claims in abortion. PMID- 6901589 TI - Patho-physiology of kallikrein system. AB - The properties of the contact factors, factor XII, high molecular weight kininogen and prekallikrein are described as well as the abnormalities in the hereditary deficiencies of these proteins. The interactions of each of these proteins with the other as well as their regulation by plasma proteolytic inhibitors such as Cl inhibitor and antithrombin III are delineated. Biochemical techniques for measuring this system are discussed. Conditions associated with abnormal synthesis of these proteins are described. Diseases in which increased kinin formation has been documented as well as disorders where there is strong evidence for the activation of kallikrein are presented. Further knowledge of this system should increase our understanding of its pathophysiological alterations. PMID- 6901590 TI - Evidence that an autoantibody of IgG3 subclass against C3b discloses a C3 Nef activity in a pateint with partial lipodystrophy and glomerulonephritis. AB - Immunoglobulins of IgG3 subclass were purified from the serum of a patient with partial lipodystrophy and glomerulonephritis. The immunochemical data clearly showed that the immunoglobulins were directed against newly-formed determinants on C3 molecule when activation of complement occurred. This autoantibody property was related to the C3 nephritis factor activity present in the serum of the patient. Furthermore, this serum was unable to destroy cell bound C3b. This result suggested that this patient would presented a deficiency of C3b inactivation system. PMID- 6901591 TI - Antimicrobial susceptibility of Aeromonas hydrophila. AB - Minimal inhibitory concentration determinations and disk diffusion and Autobac 1 susceptibility tests were performed on 22 strains of Aeromonas hydrophila. Eleven of the strains had discrepancies between Autobac and disk diffusion or minimal inhibitory concentration results. These discrepancies occurred with the beta lactam antibiotics, primarily carbenicillin and cephalothin. It is recommended that any strain of A. hydrophila found to be susceptible to any of the beta lactam antibiotics by using Autobac 1 should be retested by a disk diffusion or minimal inhibitory concentration method. PMID- 6901593 TI - Treatment of experimental staphylococcal infections: effect of rifampin alone and in combination on development of rifampin resistance. AB - Rifampin is a potentially useful anti-staphylococcal agent, but resistance develops frequently when the drug is used alone. The efficacy of rifampin, trimethoprim, and a penicillin alone or in combination was examined in mice with acute or subacute infections. Mice were infected intraperitoneally with penicillin-susceptible Staphylococcus aureus. Survival after penicillin therapy was only 9.1% in contrast to survival after rifampin therapy which was 68% (P less than 0.001). No rifampin-resistant S. aureus were isolated from peritoneal fluid or heart blood samples from dead animals in these short-term experiments. Rifampin was ineffective (survival, 4.8%) for infections instituted with rifampin resistant strains. Long-term experiments were conducted after intravenous injection of 4 x 10(8) S. aureus. Forty percent of the animals survived after methicillin therapy; 77% survived after rifampin therapy (P less than 0.001). However, 40% of those animals that died after rifampin therapy died with rifampin resistant organisms. No animal dying in groups treated with a combination of rifampin and trimethoprim (85% survival) or rifampin and methicillin (79% survival) died with rifampin-resistant organisms. Thus, rifampin combined with a penicillin or trimethoprim was effective in preventing the development of rifampin-resistant strains. PMID- 6901592 TI - Susceptibility testing of clinically isolated anaerobic bacteria by an agar dilution technique. AB - Agar dilution minimal inhibitory concentrations (MICs) of penicillin, tetracycline, chloramphenicol, and clindamycin were determined using Wilkens Chalgren agar for 1,266 clinical isolates of anaerobic bacteria. In addition, a reference strain of Bacteroides fragilis was repeatedly tested and demonstrated the precision of the technique. Fifty-six percent of our Bacteroides melaninogenicus strains were resistant (MIC greater than or equal to 4.0 microgram/ml) to penicillin. Resistance to this antibiotic was also seen among other anaerobes, but the results are more in accord with previous reports. Resistance to tetracycline (MIC greater than or equal to 4.0 microgram/ml) was found in 60% of our isolates. Chloramphenicol proved to be the most effective agent in vitro with only 2.0% of strains resistant (MIC less than or equal to 16 microgram/ml). Only 5% of strains were resistant to clindamycin (MIC greater than or equal to 8.0 microgram/ml), and this included 10 isolates of B. fragilis and 4 of B. melaninogenicus. The incidence of resistance of anaerobic bacteria to these frequently used antibiotics is greater than previous reports and indicates the need for reliable susceptibility testing of anaerobic bacteria. PMID- 6901594 TI - Antibiotic resistance in Neisseria denitrificans. AB - An ampicillin-resistant strain of Neisseria denitrificans was produced by serial passage of the organisms in media containing increased concentrations of antibiotic. The 400-fold increase in resistance obtained was a relatively stable characteristic. Ampicillin resistance in this organism was apparently related to a loss or modification of the penicillin-binding proteins associated with the cytoplasmic membranes. Membranes isolated from the ampicillin-resistant strain bound significantly less radioactive penicillin than those isolated from the parent strain and revealed one major and three minor penicillin-binding proteins. All four penicillin-binding proteins were present in reduced amounts or had a decreased capacity for penicillin binding in the ampicillin-resistant cells. The increased resistance did not involve enzymic degradation of the antibiotic or a general reduction in the permeability of the outer layers of the cell. No difference in the amount of peptidoglycan present in the parent and ampicillin resistant cells or in the gross chemical structure of the peptidoglycans of the two strains was observed. PMID- 6901596 TI - At Whiteriver ENT clinic, home visits bring care to Apaches. PMID- 6901595 TI - Activity of ten cephalosporins on biomass of methicillin-susceptible and resistant Staphylococcus aureus. AB - The growth curves automatically recorded and printed during the action of 10 cephalosporins on methicillin-susceptible and methicillin-resistant Staphylococcus aureus showed the following. (i) The biomass of methicillin susceptible S. aureus exposed to the cephalosporins increased before lysis occurred (inoculum, 10(6) colony-forming units per ml). Lysis was more rapid with cephalothin and cephaloridine, whose minimal inhibitory concentrations were lowest. (ii) The same biomass increase followed by lysis occurred with methicillin-resistant S. aureus, and the speed of lysis was not different from those of cephalothin (without any regrowth), cefoxitin (with regrowth of a few strains), and cephaloridine (regrowth of all strains), with methicillin susceptible strains. A 2-log increase of inoculum (10(8) colony-forming units per ml) did not modify significantly the speed of lysis with cephalothin, cephaloridine, and cefoxitin, but regrowth sometimes occurred. The early transitory lysis caused by cephaloridine, cephalothin, cefamandole, and cefoxitin was not suppressed by preincubation with 32 mug of methicillin per ml, but regrowth occurred more frequently. No lysis could be observed with cefazolin, cefotaxime, cephalexin, cephradine, cefuroxime, and cefaclor unless high concentrations were achieved. (iii) From a practical point of view, the early response of the growth curve (4 h) could not determine in every case whether a strain of S. aureus was resistant or susceptible to cephalosporin. A further study of the growth curve (18 of 24 h) was necessary for this purpose. Results obtained after a few hours with automated systems should be interpreted with great caution. PMID- 6901597 TI - Study identifies children at risk for otitis media. PMID- 6901598 TI - Research ethics for the clinical nurse. PMID- 6901599 TI - Nursing assessment of preoperative anxiety. PMID- 6901600 TI - OR experience in the professional doctorate. PMID- 6901602 TI - Legislators look askance at mandatory CE. PMID- 6901601 TI - "Crash course" for scrub nurses carries risk. PMID- 6901604 TI - How should patients be addressed? PMID- 6901603 TI - Surgery open house for OR nurse day. PMID- 6901605 TI - Federation, AORN share concerns on nursing future. PMID- 6901606 TI - Perils and pitfalls of plagiarism and how to avoid them. PMID- 6901607 TI - AORN members pay the cost of "free lunches". PMID- 6901608 TI - Chemical indicators recommended both inside and outside. PMID- 6901609 TI - Mechanism of action of the wheat germ ribosome dissociation factor: interaction with the 60 S subunit. PMID- 6901610 TI - Enhancement of human leukocyte elastase activity by ionic strength. PMID- 6901611 TI - In vivo monoamine oxidase inhibition by d-amphetamine. PMID- 6901612 TI - Interaction of dansylated peptidyl chloromethanes with trypsin, chymotrypsin, elastase, and thrombin. AB - A series of N alpha-1-(dimethylamino)-5-naphthalenesfulfonyl (dansyl) derivatives of peptidyl chloromethanes (chloromethyl ketones) were synthesized and employed to introduce the fluorescent dansyl moiety specifically into the active sites of proteinases via affinity labeling. Dansylalanyllysychloromethane (DALCM) was utilized to inactivate and fluorescently label trypsin and the trypsin-like enzyme thrombin. Dansylleucylphenylalanylchloromethane (DLPCM) was synthesized and selectively employed as an inhibitor of chymotrypsin. The di-, tri-, and tetrapeptides--dansylprolylalanylchloromethane (DPACM), dansylalanylprolylalanylchloromethane (DAPACM), and dansylprolylalanylprolylalanylchloromethane (DPAPACM)--were synthesizedand their interaction with elastase was evaluated. The compounds DALCM, DLPCM, and DAPACM all proved to be effective, fast-acting proteinase inhibitors. Studies of energy transfer in the enzyme-inhibitor conjugates led to results entirely consistent with the proposed conformational bomology of thrombin with the other serine proteinases studied. The fluorescent affinity labels are believed to posses enormous potential for the localization, isolation, and characterization of enzymes. PMID- 6901613 TI - Inhibition of human pancreatic elastase 2 by peptide chloromethyl ketones. AB - The inactivation of human pancreatic elastase 2 (EC 3.4.21.11) by a series of peptide chloromethyl ketones has been investigated. Among a series of compounds with the structure X-Ala-Ala-Pro-Y-CH2Cl (where X=acetyl-, succinyl-, methylsuccinyl-, or H-), the kinetic parametrs for inhibition of elastas 2 depend markedly on the amino acid (Y) in the P1 position. Succinyl-Ala-Ala-Pro-Leu-CH2Cl was found to be an extremely effective inhibitor of human elastase 2, qith a first-order rate constant for covalent bond formation (k3) of 0.033s-1 and a dissociation constant, Ki, for the enzyme inhibitor complex of 7.4 . 10(-7) M. The second-order rate constant k3/Ki for inhibition of elastase 2 by the analogous compound containing a free amino group in place of the succinyl moiety is 150 times lower than that found for the succinyl or acetyl derivative, suggesting that the presence of a positive charge at this position reduces the proper binding of the inhibitor to the enzyme. PMID- 6901614 TI - Metabolic properties and ultrastructure of alveolar type II cells isolated with elastase. AB - We used porcine pancreatic elastase to isolate type II cells from the lungs of rats; the yield and purity of the type II cells was better than that obtained by methods using trypsin. In 102 experiments we obtained 82 +/- 23 . 10(6) cells/rat, 68 +/- 11% (mean +/- S.D.) of which type II cells. This preparation of cells, when centrifuged over a discontinuous density gradient, yielded 25 +/- 10 . 10(6) cells/rat, 80 +/- 13% of which were type II cells (n = 102). The cells, after density gradient centrifugation, could be futher purified by centrifugal elutriation (94 +/- 3% type II cells, n = 22) or adherence in primary culture (94 +/- 2% type II cells, n = 34). Type II cells isolated with elastase are similar morphologically and biochemically to type II cells isolated from rats with trypsin. The preparations of cells appeared healthy by several different criteria: ultrastructure, exclusion of vital dye, lack of stimulation of oxygen consumption by exogenous sodium succinate, and linear rates of oxidation of [1 14C]palmitic acid and of incorporation of [1-14C]acetate into fatty acids. Type II cells consumed 75 +/- 20 nmol O2/10(6) cell per h, oxidized [1-14C]palmitic acid at a rate of 0.4 nmol/10(6) cells per h, and incorporated [1-14C]acetate into fatty acids at a rate of 7.5 nmol/10(6) cells per h. PMID- 6901615 TI - Phorbol myristate acetate induces the secretion of an elastase by populations of resident and elicited mouse peritoneal macrophages. AB - Cultured thioglycollate-elicited mouse peritoneal macrophages secrete an enzyme which hydrolyzes [3H]elastin prepared by NaB3H4 reduction of bovine ligamentum nuchae elastin. Over a 24 h culture period, 3.5 . 10(6) thioglycollate-elicited cells secrete sufficient enzyme to solubilize 200--350 micrograms [3H]elastin in 18h. Secretion at this rate continues for at least 6 days in culture. Secretion of the enzyme is stimulated 3-fold by exposure of the cultured cells to 10(-7) M phorbol myristate acetate, whereas the parent alcohol 4 alpha-phorbol is inactive in this respect. Enzyme activity is linearly related to the amount of conditioned medium assayed and is linear over incubation times up to 30 h. Unlabelled elastin competitively inhibits the solubilization of [3H]elastin. The solubilization rate is doubled if the substrate is pretreated with sodium dodecyl sulfate, but the rate of solubilization of this pretreated substrate increases with time. Resident peritoneal macrophages secrete barely detectable amounts of elastase, but phorbol myristate acetate (10(-7) M) stimulates its secretion in amounts comparable to those secreted by phorbol myristate acetate-stimulated thioglycollate-elicited cells. Dexamethasone (10(-9) M) inhibits phorbol myristate acetate-induced secretion by 50%, but 10(-6) M indomethacin is without effect. The secreted enzyme has the characteristics of a metalloproteinase. PMID- 6901616 TI - Legal impact of Title 22 on practice procedures. PMID- 6901617 TI - Farming and stress. PMID- 6901618 TI - Helping patient and family cope with diagnosis of a terminal illness in the hospital setting. PMID- 6901619 TI - Vacations, recreation and other stresses. PMID- 6901620 TI - Stress. PMID- 6901621 TI - You and the law: the responsibility of the patient. PMID- 6901622 TI - Spotlight on aging. Part 1. A self-help guide to the aging process. PMID- 6901623 TI - A geriatric crisis. PMID- 6901624 TI - Spotlight on aging. Part 2. Reality orientation: establishing a climate of trust in geriatric care. PMID- 6901625 TI - Spotlight on aging. Part 3. Seniors: a target for nutrition education. PMID- 6901626 TI - Self-help groups for parents of premature infants. PMID- 6901628 TI - Nurses unions, professional associations and you. Part 1. Nurses take the union route. PMID- 6901627 TI - Income tax and the self-employed nurse. PMID- 6901629 TI - Nurses unions, professional associations and you. Part 2. The role of the nurse manager in labor relations. PMID- 6901630 TI - Malignant hyperthermia need not be lethal. PMID- 6901631 TI - A time to be born, a time to die. PMID- 6901632 TI - Whatever happened to the spiritual dimension? PMID- 6901633 TI - A developing framework for oncology nursing. PMID- 6901634 TI - Fire. PMID- 6901635 TI - A practical goal for the 80's. PMID- 6901636 TI - Patient education. PMID- 6901637 TI - Students with cancer: a school nursing perspective. PMID- 6901639 TI - Counteracting burn-out for the hospice care-giver. PMID- 6901638 TI - Development and evaluation of chemotherapy fact sheets. PMID- 6901640 TI - A matter of time. PMID- 6901641 TI - Cancer nursing and the law: informed refusal. Part III. PMID- 6901643 TI - Immunology: immunotherapy II. Programmed instruction: cancer care. PMID- 6901642 TI - An unusual accident during the administration of chemotherapy. PMID- 6901645 TI - [Study of the nursing theory based on one's own experience]. PMID- 6901644 TI - [The effect of ionizing radiation on enzymes. I. The effect of gamma radiation on proteolytic activity of pancreatin of various degrees of purity]. PMID- 6901646 TI - [Nursing and formats of education (5) - postgraduate education (1)]. PMID- 6901647 TI - [A patient's concern with death]. PMID- 6901648 TI - [Pleasure associated with improvement of the nursing work condition - selecting a daily problem as a topic of nursing research]. PMID- 6901649 TI - [Research on the design of a meal table for the patient in a supine position]. PMID- 6901650 TI - [Re-establishment of one's own nursing philosophy and a thought on its relationship to nursing technology]. PMID- 6901651 TI - [In response to the gaze of the patient]. PMID- 6901652 TI - [The position of the nursing study in the changing academic trends]. PMID- 6901653 TI - [Basic theory of nursing: outline of the course. (8: conclusion)]. PMID- 6901654 TI - Care study: Mr. Poot and family. PMID- 6901655 TI - Varicose ulcers. PMID- 6901656 TI - Pneumothorax. PMID- 6901658 TI - Psychological reactions to myocardial infarction. Part II. Psychosocial update! PMID- 6901657 TI - Hemoptysis. Respiratory care update! PMID- 6901659 TI - Field flight assessments. Emergency care update! PMID- 6901660 TI - Patient management of systemic lupus erythematosus. PMID- 6901662 TI - The effects of octylglucoside on the Semliki forest virus membrane. Evidence for a spike-protein--nucleocapsid interaction. AB - Evidence is presented for a non-covalent interaction between the spike glycoprotein and the nucleocapsid of Semliki Forest virus. When isolated viruses were treated with the non-ionic detergent beta-D-octylglucoside at neutral pH and low ionic strength the lipid bilayer membrane could be removed leaving most of the spike glycoproteins attached to the nucleocapsids. The interaction between capsids and membrane protein was sensitive to elevated pH and ionic strength, but at least partially reversible at neutral pH and low ionic strength. The possible role of this interaction in the viral structure and in the mechanism of budding of the virus from the host cell is discussed. PMID- 6901661 TI - Problems and challenges in the treatment of the aging patient. PMID- 6901663 TI - The indirect mechanism of action of the trifluoroacetyl peptides on elastase. Enzymatic and 19F NMR studies. AB - Trifluoroacetyl (CF3CO) dipeptide anilides are potent reversible inhibitors of elastase. Their 19F NMR spectra in the presence of the enzyme correspond therefore to slow chemical exchange. Their characteristics are very similar to those previously reported for other CF3CO-peptides. This should correspond to a single binding mode, in which the CF3CO group lies in a specific site in close contact with protein protons. Elastase, irreversibly inhibited by alkylation of Ser-195 with phenylsulfonyl fluoride derivatives, binds the CF3CO-Ala-containing dipeptide anilides still more tightly than the native enzyme. It no longer binds the dipeptide anilides containing a bulky CF3CO-Lys group, suggesting a location of the CF3CO site near the S1 subsite. On the other hand, the chemical shift of the CF3CO 19F resonance in the complex is the only NMR property affected by the enzyme sulfonylation, the T1 and nuclear Overhauser effect values being unmodified as compared to those in the complexes with the native enzyme. The observation of the NMR characteristics of elastases inhibited by phenylsulfonyl groups substituted with fluorine shows that complexation with CF3CO-peptides induces a change of conformation of the catalytic site which should correspond to a displacement of His-57 toward the ortho position of the phenylsulfonyl ring. Such a transconformation is not observed with corresponding acetylated peptides. The phenylsulfonyl fluoride derivatives are still able to react with elastase in the presence of a large excess of CF3CO-peptides. In such conditions the rate of inactivation is much slower but still at least 5% of that measured in the absence of the reversible inhibitors. This residual activity is hardly compatible with the presence of two exclusive modes of interaction of the CF3CO-peptides with native elastase. On the contrary, these observations are better interpreted by a single and identical mode of binding of the peptide to the native and sulfonylated enzymes. According to this mode of binding, the reversible inhibition of elastase by CF3CO-peptides should correspond to an indirect mechanism by which a change of conformation at the active site results in a reduced catalytic activity. PMID- 6901665 TI - [Sepsis in infants]. PMID- 6901664 TI - Ureteral contractions induced by rat urine in vitro: probable involvement of renal kallikrein. AB - Rat urine, even at a 1:10 final dilution in Tyrode's solution, stimulates contraction of the ureteral musculature in vitro. This effect can be ascribed to the presence of kallikrein or a kallikrein-like enzyme in urine. Isometric contractions of ureters were prevented by previous addition of aprotinin to the organ bath. Urine also lost its activity after inactivation of enzymes by heat or acid treatment. PMID- 6901666 TI - [Nutrition during pregnancy]. PMID- 6901667 TI - [Anesthesia in labor]. PMID- 6901668 TI - [Action of alcohol on the fetus and progeny]. PMID- 6901669 TI - [Work of preliminary admission offices in the polyclinic]. PMID- 6901671 TI - [Drug anaphylactic shock]. PMID- 6901672 TI - [Medical codes in the USA and private medical practice]. PMID- 6901670 TI - [Sleep disorders]. PMID- 6901673 TI - [Modern sulfanilamide preparations]. PMID- 6901674 TI - [Content of family hygienic instruction in home care for infants in the 1st year of life (material for discussions)]. PMID- 6901675 TI - [Conducting practical exercise at a first aid station]. PMID- 6901676 TI - [Tuberculosis of the female genital organs (clinical aspects, differential diagnosis, treatment and dispensary observation)]. PMID- 6901678 TI - [No hospitalization for tuberculosis patients]. PMID- 6901677 TI - [Drug therapy of rheumatoid arthritis]. PMID- 6901679 TI - [Phenylketonuria]. PMID- 6901680 TI - [Concepts of nursing care]. PMID- 6901681 TI - [The intermediate program for nursing and midwifery care in Europe]. PMID- 6901682 TI - [Organization of rehabilitation centers in the Netherlands. Nursing care with your hands behind your back?]. PMID- 6901684 TI - Activity and subcellular distribution of initiation factor eIF-2 in extracts of well-fed and amino acid-starved Ehrlich ascites-tumour cells [proceedings]. PMID- 6901683 TI - Regulation of protein synthesis in Ehrlich ascites tumour cells in culture. PMID- 6901685 TI - Regulation of polypeptide-chain initiation in Ehrlich ascites-tumour cells by amino acid starvation [proceedings]. PMID- 6901686 TI - Effects of storage on anti-elastolytic properties of normal human serum [proceedings]. PMID- 6901688 TI - How do you answer. Hey, what's in it for me? Why should I joint? PMID- 6901689 TI - Dealing with the issue of death and dying. PMID- 6901687 TI - Genetic linkage between Bf S0.7 (Bf S1) and HLA-Bw50. AB - Two hundred and one unrelated French Basque individuals were studied for HLA-A, B, C, DR and Bf polymorphisms. The results show that the Bf S0.7 (Bf S1) variant, which is known to be associated with HLA-Bw21, presents a highly significant linkage disequilibrium with a subtypic specificity, i.e., Bw50 (delta = 0.0123, delta S=100%, P less than 10(-8)). As neither Bf S0.7 variant nor Bw50 antigen is found in Mongoloid populations, it is suggested that in evolutionary terms, the Bf S0.7 mutation is a more recent event than the HLA-Bw21 split. PMID- 6901690 TI - Nurses' order: political action in 1980. PMID- 6901692 TI - An interview: why nursing? PMID- 6901691 TI - Plan ahead for the BSN. PMID- 6901693 TI - How to maximize your clinical experiences. PMID- 6901694 TI - The ERA era. PMID- 6901695 TI - Kennedy - on health. PMID- 6901696 TI - The O.R. needs you! PMID- 6901697 TI - Can I come close enough to touch you? PMID- 6901698 TI - [Questions raised about the utilization of a new treatment for oozing wounds: dextranomere]. PMID- 6901699 TI - [Reflexions of a nurse on the fight against tuberculosis after the closure of numerous dispensaries: reality or utopia?]. PMID- 6901700 TI - [The psychiatric nurse. Dyslexia]. PMID- 6901701 TI - [Decubitus ulcers]. PMID- 6901702 TI - [Social security in the framework of and the European Economic Community]. PMID- 6901703 TI - Complement activation by Coccidioides immitis: in vitro and clinical studies. AB - Mycelial- or spherule-phase derivatives of Coccidioides immitis caused a decrease in vitro of total hemolytic complement in serum from a nonsensitized person. Activation involved both classic and alternative pathways as shown by deprssion of hemolytic C4 and by generation of products of activation of components C3, C4, and factor B. In addition, functional complement activity or immunoreactive levels of complement components or both were measured in 23 patients with self limited or disseminated coccidioidomycosis. Low total hemolytic complement was found in nine, usually during the early phase of primary illness, and was transient. Hemolytic C4 was low, and the effect of inulin to decrease complement levels was blunted, suggested both classic and alternative pathways may be deficient. However, associated depression of immunoreactive levels of components assayed (C3, C4, C5, factor B, and properdin) was not consistently found. This disparity raises the possibility of enhanced in vitro inactivation analogous to activation by immune complexes. PMID- 6901705 TI - [Point blank. Criticism will pour down...harmony will guide evolution]. PMID- 6901704 TI - [Fertility under the guidelines of health, autonomy and responsibility]. PMID- 6901706 TI - And all that jazz. PMID- 6901707 TI - A data bank of closed circuit videotape recordings on health care techniques and its effects on the quality of health care. PMID- 6901708 TI - [Nursing the adult patient with aphasia]. PMID- 6901709 TI - [Audiology programs: another point of view]. PMID- 6901710 TI - [Income taxes for self employed nurses]. PMID- 6901712 TI - [Judicial aspects. Hospitals and nurses: evolution of judicial responsibility]. PMID- 6901711 TI - [Experience]. PMID- 6901713 TI - Hyperuricosuria in cystic fibrosis patients treated with pancreatic enzyme supplements. A study of 16 patients in Israel. AB - Uric acid metabolism was evaluated in 16 Israeli cystic fibrosis patients, all of whom were taking pancreatic enzyme supplements. The findings were compared with those in a recent study of uric acid metabolism in 65 healthy Israeli children. Hyperuricemia of 4.9 +/- 0.2 (SE) mg/dl was found in the cystic fibrosis patients, compared with a normal level of 3.1 +/- 0.2 mg/dl ( P < 0.05). In five patients, 24-h urine collections were assayed and all showed hyperuricosuria. Thirteen patients had high urinary uric acid/creatinine ratios. Hyperuricosuria increased with the age of the patient and when the administered dosage of pancreatic enzyme exceeded 10,000 lipase units/kg body weight. Despite normal levels of serum creatinine and urea, and normal creatinine clearance in the cystic fibrosis patients, risk of future renal damage seems obvious and preventive measures should be considered. PMID- 6901714 TI - Prevention: an exploratory study of health visiting in England, Wales and Scotland. PMID- 6901715 TI - The health visitor in court - 3. PMID- 6901717 TI - The relevance of sociology to health visitors. PMID- 6901716 TI - A further education course for health visitors. PMID- 6901718 TI - The National Childminding Association. PMID- 6901719 TI - An enuresis clinic. PMID- 6901720 TI - Patients first. Comments on 'Patients first', the consultative paper on the structure and management of the National Health Service in England and Wales. PMID- 6901721 TI - Ethnic minorities. PMID- 6901723 TI - Health visiting with a difference. PMID- 6901722 TI - Health visiting Vietnamese refugees in Britain. PMID- 6901724 TI - Changing patterns of conception and fertility. PMID- 6901725 TI - Nutrition. PMID- 6901726 TI - Focus on school health. The National Study of Health and Growth (NSHG): surveillance on nutritional status of primary schoolchildren. PMID- 6901727 TI - Health education: health interests of children. PMID- 6901728 TI - Vitamin D -- too much of a good thing? PMID- 6901729 TI - How adequate are vegan diets for children? PMID- 6901730 TI - Know your organizations: National Women's Aid Federation. PMID- 6901731 TI - Thoughts of a health visitor housewife. PMID- 6901732 TI - A visit to Sweden. PMID- 6901733 TI - Paradoxical effects of protein synthesis inhibitors on uridine uptake in cultured cells: possible role of uncharged tRNA in regulating metabolism. AB - Previous studies (J. Biol. Chem, 253: 99--105, 1978) showed that thyrotropin releasing hormone (TRH) acutely stimulated uridine uptake in pituitary cell (GH 4Cl)) cultures. Studies on the role of protein synthesis in this response to TRH led to the finding that an inhibitor of ribosomal translation, cycloheximide, also stimulated uridine uptake acutely. Studies reported here attempt to determine the mechanism of cycloheximide action and whether cycloheximide and hormone stimulation of uridine uptake occurred by similar pathways. The experiments presented indicate that: (1) seven inhibitors of ribosomal translation stimulated uridine uptake; (2) in contrast, inhibition of protein synthesis at tRNA aminoacylation resulted in reduced rates of uridine uptake; (3) inhibition of tRNA aminoacylation blocked cycloheximide but not TRH stimulation of uptake; (4) cycloheximide stimulation of uptake was restricted to amino acid depleted cultures; (5) amino acid supplementation stimulated uridine uptake with a time-course identical to that of cycloheximide; (6) cycloheximide and amino acid supplementation promoted reacylation of cellular tRNAs in amino acid depleted cultures; and (7) cycloheximide stimulation of uridine uptake resulted from enhanced nucleoside phosphorylation rather than increased uridine transport. We conclude that cycloheximide and amino acid stimulation of uridine phosphorylation may be mediated through a common pathway involving the extent of amino-acylation of cellular tRNAs. Furthermore, cycloheximide and TRH stimulate uridine phosphorylation by pathways that are distinguishable. It is apparent that not all cellular effects of cycloheximide can be attributed solely to inhibition of the synthesis of proteins. PMID- 6901735 TI - The Meharry way: program of guided studies: RN to BSN. PMID- 6901736 TI - Evaluating a continuing education program. PMID- 6901734 TI - Immunoassay of serum conjugates of cholic acid in cystic fibrosis. AB - Pre- and post-prandial serum conjugates of cholic acid (SCCA) were measured by radioimmunoassay (RIA) in 83 patients with cystic fibrosis (CF), 14 of whom did not have steatorrhoea, and in 25 controls. Of the CF patients with steatorrhoea, 38% had fasting SCCA levels greater than 3 standard deviations above mean fasting control values, whereas no CF patient without steatorrhoea had elevated fasting SCCA levels. Steatorrhoeic patients with palpable livers had higher pre- and post prandial SCCA levels. Post-prandial SCCA levels failed to discriminate between control and CF groups however. Other serum tests of liver function, including the aspartate amino transferase, alkaline phosphatase, albumin, gamma globulin, and albumin : globulin ratio, failed to correlate with the SCCA. Changes in serum protein constituents correlated strongly with pulmonary dysfunction. The results suggest that elevation of fasting SCCA levels in CF patients is a more sensitive indicator of liver dysfunction than other tests and is a better discriminator than post-prandial SCCA levels between normal and abnormal liver function. The test is recommended for early detection of liver dysfunction in CF patients. PMID- 6901737 TI - Personal qualities of nurses implying need for continuing education to increase interpersonal and leadership effectiveness. PMID- 6901738 TI - Methods of teaching-revisited self-instructional modules. PMID- 6901743 TI - You have been here before. PMID- 6901739 TI - Statewide continuing education needs assessment in nursing: the SNAP system. PMID- 6901741 TI - Thinking about learning: because I am a learner, what questions should I ask myself as a facilitator? PMID- 6901740 TI - Statewide continuing education for nurses increases accessibility to university resources. PMID- 6901742 TI - Developing a department of continuing education in a diploma nursing school. PMID- 6901744 TI - A study of morale in low income blacks. PMID- 6901745 TI - Decubitus prevention through early assessment. PMID- 6901746 TI - Informal activity invovlvement and the perceived rate of time passage for an older institutionalized population. PMID- 6901747 TI - Self-administration of drugs in the elderly: nursing responsibilities. PMID- 6901748 TI - Voluntary relocation among the elderly: nursing implications. PMID- 6901750 TI - Undergraduate education in gerontological nursing: integration or separation? PMID- 6901749 TI - Know your community resources. Hospice care at home: an alternative. PMID- 6901751 TI - The need for personal space in institutions for the elderly. PMID- 6901752 TI - Aging as deviance - nursing implications. PMID- 6901754 TI - An adventure in geriatric nursing. PMID- 6901753 TI - Criteria leading to quality control in rehabilitation: the elderly patient - a team member. PMID- 6901755 TI - Developing an effective long-term prospective study. PMID- 6901756 TI - Death with dignity. PMID- 6901757 TI - Vanadate as a transport probe. PMID- 6901759 TI - [Theory and practice of group therapy]. PMID- 6901758 TI - The renal response to intravenous vanadate in rats. PMID- 6901761 TI - [Nursing care of a patient with cultural bound syndrome]. PMID- 6901760 TI - [Primary nursing: how to take a health history]. PMID- 6901762 TI - [Understanding the defense mechanisms]. PMID- 6901763 TI - Suicide and the university student - a population at risk. PMID- 6901764 TI - [Suicide and the university student - a population at risk]. PMID- 6901765 TI - [Recognize DIC syndrome]. PMID- 6901766 TI - [Medication errors]. PMID- 6901767 TI - [Tumor and malignant transformation]. PMID- 6901768 TI - [A report on the knowledge of, and attitude toward contraceptive methods of students in National Chung-Hsing University]. PMID- 6901769 TI - [Patient's adverse reactions during hemodialysis - a primary study]. PMID- 6901770 TI - [Practicing group psychotherapy in a psychiatric ward]. PMID- 6901772 TI - Visible particle limits in small volume parenterals. PMID- 6901771 TI - [Primary nursing is alive and well in the hospital]. PMID- 6901773 TI - Degradation of dextrose during heating under simulated sterilization. PMID- 6901774 TI - Theoretical aspects of particulate matter monitoring by microscopic and instrumental methods. PMID- 6901776 TI - Pfizer's DRUMBEAT program. PMID- 6901777 TI - Parenteral fundamentals. Basic principles and applications of bioindicators. PMID- 6901778 TI - Nutrition and the elderly. PMID- 6901775 TI - Low temperature vacuum drying: evaluation of excipients in injectable dosage forms. PMID- 6901780 TI - Alternate avenues: unique career paths for LP/VNs. Home health care. PMID- 6901779 TI - Drugs and the elderly. What the nurse should know. PMID- 6901781 TI - Innovative programs in geriatric care. PMID- 6901782 TI - Don't give up! There are many ways to reach the elderly. PMID- 6901784 TI - Emotional (over) involvement. Can a nurse care "too much" for a patient? PMID- 6901785 TI - Pharmacology update. Cephalosporin antibiotics--Part III. PMID- 6901783 TI - Community health in the Guatemalan highlands. PMID- 6901786 TI - [Fundamental and clinical studies on sisomicin in children (author's transl)]. AB - Fundamental and clinical studies on sisomicin, a new aminoglycoside antibiotic were carried out and the following results were obtained. 1. Antibacterial activity of sisomicin was superior to that of gentamicin, amikacin, cefazolin and ampicillin against S. aureus and Ps. aeruginosa. Against E. coli and K. pneumoniae, it was superior to that of amikacin, cefazolin, ampicillin and equal or slightly superior to that of gentamicin. 2. Mean serum levels of sisomicin were 18.0 +/- 0.5 microgram/ml, 15.7 +/- 1.3 microgram/ml, 9.6 +/- 0.6 microgram/ml, 3.2 +/- 0.4 microgram/ml, 1.7 +/- 0.2 microgram/ml and 0.95 microgram/ml at 1/2, 1, 2, 4, 6 and 8 hours after a single intramuscular administration of sisomicin 2.0 mg/kg to 3 children. Mean half-life time was 1.6 +/- 0.2 hours. Mean urinary recovery was 60.4 +/- 7.5% within 6 hours after administration of sisomicin 1.6-2.1 mg/kg to 4 children. 3. Sisomicin was given intramuscularly to 13 children with acute pyelitis (11), acute cystitis (1) and stomatitis gangrenosa and cervical lymphadenitis (1). The daily dose was 2.0 -4.2 mg/kg, divided into twice. Clinical response was excellent in 8 and good in 5. In bacteriological examinations, 13 pathogens (E. coli 9, K. pneumoniae 2, Ps. aeruginosa 2) were eradicated after administration. No adverse reactions were observed. PMID- 6901788 TI - [The theory and practice of the Lamaze method]. PMID- 6901787 TI - Genetic polymorphism of serum proteins and levels of immunoglobulin and complement components in high caste community (Brahmins) of Madhya Pradesh, India. PMID- 6901792 TI - [Expectant mothers' return to her parents' homes to give birth--physical symptoms associated with extended travelling]. PMID- 6901790 TI - [The problem of health manpower and the role of the traditional birth attendant]. PMID- 6901789 TI - [Course on Lamaze method for both parents]. PMID- 6901791 TI - [Nursing to encourage breast feeding. I. Conditions of the mother and child 1 to 2 weeks following discharge from the hospital. II. Status of breast feeding 1 to 2 weeks following discharge from the hospital and reasons for switching to bottle feeding]. PMID- 6901793 TI - [Nursing of a patient with hyperemesis gravidarum and exaggerated psychological tension]. PMID- 6901794 TI - [Pregnancy and alcohol drinking]. PMID- 6901795 TI - [Diagnosis of toxoplasmosis in pregnancy]. PMID- 6901796 TI - [Pregnancy and food habits. The nutritional state of the pregnant woman observed by midwives in clinical facilities. 2. The nutritonal status in the district sercice]. PMID- 6901797 TI - [Pregnancy and food habits. Maternal nutrition and its concept]. PMID- 6901798 TI - [Pregnancy and food habits. The nutritional state of the pregnant woman observed by midwives in clinical facilities. 2. The nutritional state observed at the obstetrical ambulatory department]. PMID- 6901799 TI - [Pregnancy and food habits. Starting point in nutritional education--an approach to maternal and child health care by the municipal government]. PMID- 6901800 TI - [Pregnancy and food habits. Practice of nutritional education of pregnant and puerperal patients]. PMID- 6901801 TI - [Pregnancy and food habits. Food habits of high school girls--the status of the future mothers]. PMID- 6901802 TI - [Care of a patient with myasthenia gravis throughout two pregnancies]. PMID- 6901803 TI - [Determination of timing of delivery by the extent of cervical maturation]. PMID- 6901804 TI - [Maternal idiopathic thrombopenic purpura and the newborn infant]. PMID- 6901805 TI - [Maternal health care and obstetrical problems of working women]. PMID- 6901806 TI - [Maternal health care and equal employment opportunities for women]. PMID- 6901807 TI - [Maternal health care reflected in working women and industries--from the surveys on "attitudes and lives of working women in Saitama prefecture"]. PMID- 6901808 TI - [A thought on the attitude of industries observed in the survey on the "attitude and lives of working women in Saitama prefecture"--with special reference to working conditions of women]. PMID- 6901809 TI - [An impression on a class for expectant mothers]. PMID- 6901810 TI - [Professionally speaking: midwifery as a nursing specialty]. PMID- 6901811 TI - [Mechanism of premature labor and agents to prevent the process]. PMID- 6901812 TI - [Practice and theories of hepatic examinations - progress in hepatic angiography]. PMID- 6901813 TI - [Implantation of an artificial lens and associated nursing - on health instruction after hospital discharge reflected in questionnaires]. PMID- 6901814 TI - [Adaptation: implications for curriculum change]. PMID- 6901815 TI - [The psychological rehabilitation of the amputee]. PMID- 6901816 TI - [Hepatectomy - current trends and its practice]. PMID- 6901817 TI - [Catheterization of the hepatic artery and its associated care]. PMID- 6901818 TI - [Drug therapy of metastatic hepatic cancer by catheterization of the umbilical vein and the care associated with the procedure]. PMID- 6901819 TI - [Prevention and management of postoperative hepatic failure]. PMID- 6901820 TI - [Nursing care before and after hepatectomy]. PMID- 6901821 TI - [Progress in the diagnosis of hepatic cancer and an overview on the early diagnosis]. PMID- 6901822 TI - [Nursing of patients with hepatic artery catheterization]. PMID- 6901823 TI - [Care and management of a patient with liver cirrhosis and live cancer]. PMID- 6901824 TI - [Conference: care of a patient with hepatic cancer treated with catheterization of the umbilical vein]. PMID- 6901825 TI - [Science of symptomatology: blood pressure. Abnormalities of the blood pressure]. PMID- 6901826 TI - [Science of symptomatology: blood pressure. The mechanism and actions of the vasomotor control system]. PMID- 6901827 TI - [Possibility of early therapy of hepatic cancer - trends in new diagnosis and therapy]. PMID- 6901828 TI - [Science of symptomatology: blood pressure. Pitfalls in planning of the care of hypertensive patients]. PMID- 6901830 TI - [Postoperative nursing of patients with complete transposition of great vessels (type I)]. PMID- 6901829 TI - [Science of symptomatology: blood pressure. Backgrounds and knowledge of the disease by hypertensive patients]. PMID- 6901831 TI - [Physiopathology and fundamentals of respiratory insufficiency]. PMID- 6901832 TI - [Prolonged respiratory insufficiency and problems in its care]. PMID- 6901834 TI - [Respiratory care following aortic valve replacement - management of a case complicated with hemothorax]. PMID- 6901833 TI - [Postoperative respiratory care of the newborn and young infants and its problems]. PMID- 6901835 TI - [Nursing of a myasthenia gravis patient with intratracheal intubation for respiration for an extended time - the effect of a team effort]. PMID- 6901836 TI - [Conference: respiratory care of a patient with chronic obstructive pulmonary disease (COPD)]. PMID- 6901837 TI - [Science of symptomatology. Respiratory difficulty and respiratory insufficiency]. PMID- 6901838 TI - [Science of symptomatology. Respiratory difficulty: regulation of the respiratory actions and the mechanism of the development of respiratory difficulty]. PMID- 6901839 TI - [Science of symptomatology. Respiratory difficulty: respiratory care at an emergency hospital - standardization of respiratory mucus extraction]. PMID- 6901840 TI - [Science of symptomatology. Respiratory difficulty: sterilization of the instrument used in tracheal aspiration]. PMID- 6901841 TI - [Science of symptomatology. Respiratory difficulty: nursing and problems associated with artificial respiration of newborn infants]. PMID- 6901842 TI - [Nursing of a 1-year-2-month-old child with a second degree 100% burn - care starting in 7 hours after the injury extending to rehabilitation]. PMID- 6901843 TI - [Care involved in arteriovenous shunt of a hemodialysis patient - with special reference to the hygienic care]. PMID- 6901844 TI - [Nursing of a hemodialysis (chronic kidney failure) patient with congenital heart defect; a study of a case undergoing open heart surgery]. PMID- 6901845 TI - [The psychological rehabilitation of the amputee. VI]. PMID- 6901846 TI - [Multiple injuries]. PMID- 6901847 TI - [Significance of case studies and problems of nursing observation--a discussion on the answers to the questionnaires by 10 respondents]. PMID- 6901848 TI - [Measures of transactional analysis ego states for nurses]. PMID- 6901850 TI - [Experiment on the workload of daily activities--the workload of shampooing in a supine position]. PMID- 6901849 TI - [Effect of basic preventive health practices and mass media on the practice of breast self-examination]. PMID- 6901851 TI - [Importance of nursing observation in case studies. Discussion]. PMID- 6901854 TI - [Recording in the study of counseling]. PMID- 6901852 TI - [Questionnaires: opinions of 10 people on case studies]. PMID- 6901853 TI - [Clinical records at a psychiatric department and their problems]. PMID- 6901855 TI - [Case study and records]. PMID- 6901856 TI - [Significance of the daily records based on the accurate grasping of the problems: discussion]. PMID- 6901857 TI - [Conference: interactions between the nurse and a child suffering from pain]. PMID- 6901858 TI - [Comparison of the attitude of the nurse and that of the matron toward nursing action at a special nursing home for the aged]. PMID- 6901859 TI - [Discussion on "An Introduction to the Theoretical Basis of Nursing" by Martha E. Rogers]. PMID- 6901860 TI - [Experience with a 2-year nursing education]. PMID- 6901861 TI - [Continuing nursing education designed to suit the professional development of nurses]. PMID- 6901862 TI - [My experience with continuing nursing education: continuing education as the source of capability for the future for a nurse facing a choice between the profession and child-rearing]. PMID- 6901863 TI - [My experience with continuing nursing education: decision making of a nurse and re-evaluation of behavior]. PMID- 6901864 TI - [My experience with continuing nursing education: changes in nursing view point, a vital support for a nurse with practical nursing education]. PMID- 6901865 TI - [My experience with continuing nursing education: a joy in self-expression at professional practice]. PMID- 6901866 TI - [Basic nursing education and on the job training. Discussion]. PMID- 6901867 TI - [Understanding of the "object" - observation of the life of the patient as a means to understand him]. PMID- 6901868 TI - [A scene with illness - 6. A day of a physician assigned to a hospital in a small town]. PMID- 6901869 TI - [Maxim in giving comfort. 2]. PMID- 6901870 TI - [Aquisition of basic knowledge and technics to enrich the clinical training]. PMID- 6901872 TI - [Elaboration on a report on clinical training, "learning process for understanding of patients' crises": an instructor's comment]. PMID- 6901873 TI - [Learning during the process of forming a relationship with the patient: use of a process record in reassignment of patients to students in clinical training]. PMID- 6901871 TI - [Learning process for understanding patients' crises: a report on clinical training in adult nursing]. PMID- 6901874 TI - [A trial at the clinical training at a public health clinic: home nursing training in cooperation with the public health nursing department]. PMID- 6901875 TI - [Observation on teaching of nursing technology in clinical training]. PMID- 6901876 TI - [The system of nursing education in the Republic of Mexico]. PMID- 6901877 TI - [Scenes with illness. 7. A funeral in a village]. PMID- 6901878 TI - [Activities directly related to medical care as the basis of public health nursing--a discussion by the public health nurses associated with the Home Nursing Section of Horikawa Hospital]. PMID- 6901879 TI - [Theories of surveys for public health nurses ( 5 ). Drawing conclusions from the accumulated data]. PMID- 6901880 TI - [Care involved in excretion]. PMID- 6901881 TI - [Health care activities in industries. 2. Its evaluation in the area of health education]. PMID- 6901882 TI - [Re-evaluation of a panel discussion--its application to health education]. PMID- 6901884 TI - [A child with Holt-Oram syndrome and health instruction for her family]. PMID- 6901883 TI - [Home nursing of aged bed-ridden patients--start of the home nursing service in our area]. PMID- 6901886 TI - [Promotion of breast feeding]. PMID- 6901885 TI - [Breast feeding over bottle-feeding]. PMID- 6901887 TI - [Financing public health clinics by taxes allocated to local governments : on the article by Sugawa]. PMID- 6901888 TI - [Financing of public health clinics by taxes allocated to local governments- rebuttal to the article by Akiyama]. PMID- 6901889 TI - [Distribution of public health nurses in relation to the public health clinics and local municipalities. (1) : the statistics concerning prefectural public health districts]. PMID- 6901890 TI - [Development of primary health care specific to Japan. A new focal point in public health activities--its' application to the evaluation of the practice of the 4 basic principles of primary health care]. PMID- 6901891 TI - [Public health nurses in Santama (3). Ms. Hisako Sawanishi, a public health nurse of Higashi-Kurume-shi and problems of urbanization]. PMID- 6901892 TI - [Life of a public health nurse--a disabled mobile unit used for gastric mass screening]. PMID- 6901893 TI - [Analysis of salt contents of "Miso" soup at Naka-machi]. PMID- 6901894 TI - [Continued nursing care investigated, using patient cards]. PMID- 6901895 TI - [Sudden death after hospitalization of housewife with schizophrenia]. PMID- 6901898 TI - [Study to determine retirement age]. PMID- 6901896 TI - [Who is wanted in the delivery room?]. PMID- 6901897 TI - [Hypertension and pregnancy]. PMID- 6901899 TI - [Even an infant is susceptible to becoming a smoker]. PMID- 6901900 TI - [Crohn's disease]. PMID- 6901901 TI - [Activities and projects of the ILO subcommittees]. PMID- 6901902 TI - [Social, economic, and welfare activities of the members of the American Nursing Association--a lesion from their group actions in negotiation]. PMID- 6901903 TI - [Dissociation from a fixed pattern in nursing]. PMID- 6901904 TI - [Finding one's own tendencies in decision-making and helping]. PMID- 6901905 TI - [Recognition of one's own tendency in nursing action: a discussion]. PMID- 6901906 TI - [Training in finding one's own emotional trends]. PMID- 6901907 TI - [Observation on the educational goals in the study of adult nursing - with special reference to nursing of young adult]. PMID- 6901908 TI - [Programmed learning. Anxiety - perception and intervention - 2]. PMID- 6901909 TI - [Flowers until it falls. 6]. PMID- 6901911 TI - Portrait: Carla Lee. PMID- 6901910 TI - [Profile of a nurse: Ms. Tachi Lazum Cho, a nurse from Kashmir studying at Nagoya Nursing College]. PMID- 6901912 TI - Dedication: Florence Nelson. PMID- 6901913 TI - Defining nursing ethics apart from medical ethics. PMID- 6901915 TI - ANA a politically oriented organization. PMID- 6901916 TI - Oral care protocals after chemotherapy? PMID- 6901914 TI - [State of the blood kallikrein-kinin system in arteriosclerosis obliterans of the lower extremities]. PMID- 6901918 TI - [How fire-safe is your hospital? An expert on fire prevention in hospitals and nursing homes]. PMID- 6901917 TI - The who, what, when, why and how of professional negotiations for nurses. PMID- 6901920 TI - [Intestinl helminthiasis]. PMID- 6901919 TI - [Arena hospital: servant or partner - against each other or together - communication problems]. PMID- 6901921 TI - [What do we really want - or how would you like it?]. PMID- 6901922 TI - [Influencing factors in the planning of job needs]. PMID- 6901923 TI - [At the limits]. PMID- 6901924 TI - A molecular model of peptide chain propagation. PMID- 6901925 TI - [Primary health care and the future of the nursing profession. Discussion]. PMID- 6901926 TI - [Primary health care and regional activities - on individual and group efforts for self help in promotion of the health of the aged]. PMID- 6901928 TI - [Primary health care and nursing profession from the viewpoint of manpower]. PMID- 6901927 TI - [Problems facing the practice of primary health care and nursing education]. PMID- 6901929 TI - [Study on nursing of patients with systemic lupus erythematosus - 2. A survey on the level of nursing capacities of nurses]. PMID- 6901930 TI - [Life science (3). Genetics and life science]. PMID- 6901931 TI - [Bedside conference on pediatric nursing. 6. Hematological diseases (3), lung diseases (1), and chromosome abnormalities (2) in children]. PMID- 6901933 TI - [A viewpoint on nursing education (3). Psychology of the instructor]. PMID- 6901932 TI - [Primary health nursing in England (3). Primary health care and nursing education]. PMID- 6901934 TI - [Teacher-student relationship. 1]. PMID- 6901935 TI - [A study on training of nursing students at the radiology department - the clinical lectures]. PMID- 6901936 TI - [Various problems concerning reassignment of nurses]. PMID- 6901937 TI - [Reassignment of the nursing personnel in view of a morale survey]. PMID- 6901938 TI - [Reassignment of nursing personnel and development of nursing capability]. PMID- 6901939 TI - [Trends in nursing specialities and reassignment of personnel]. PMID- 6901940 TI - [Nursing of patients with systemic lupus erythematosus. 3]. PMID- 6901941 TI - [Life science. 4. History of the eating mechanism - in relation to the evolution of vertebrate animals]. PMID- 6901942 TI - [Bedside conference in pediatric nursing. 7. Nursing of children with congenital heart disease. 3]. PMID- 6901943 TI - [Primary health nursing in England. 4. Primary health care and nursing management]. PMID- 6901944 TI - [Focal point in nursing education. 4. The quality of the leader expected by the students - the result of a survey among participants of a seminar for nursing instructors]. PMID- 6901945 TI - [Teacher-student relationships. 2]. PMID- 6901947 TI - New frontiers in nursing - corrections health. PMID- 6901946 TI - [Learning motivation of nursing students in various nursing courses and the factors related to their attitudes - a comparison between the 2-year and 3-year nursing courses]. PMID- 6901948 TI - American sign language: second language at Lutheran Hospital Baltimore. PMID- 6901950 TI - Transforming. PMID- 6901949 TI - Psychiatric consultation liaison nursing: 18 months later. PMID- 6901951 TI - The footwall. PMID- 6901952 TI - Kinship primitive: modern societies. PMID- 6901953 TI - Nursing education Newcastle College of Advanced Education. PMID- 6901955 TI - Consistency : The key to better nursing for the retarded. PMID- 6901954 TI - What caused the itch. PMID- 6901956 TI - An overview of community health services in England. PMID- 6901957 TI - Patient dependency studies: patient dependency classification. PMID- 6901958 TI - Myasthenia gravis. PMID- 6901960 TI - What is it a supervisor looks for? PMID- 6901959 TI - Curriculum change (The process in a school of nursing). PMID- 6901961 TI - The wearing of day clothing by patients in hospital. PMID- 6901962 TI - Labelling - some practical problems. PMID- 6901963 TI - Viewpoint: attitude to migrants. PMID- 6901964 TI - What is the use of patient dependency studies? PMID- 6901965 TI - Economics: personal and corporate perspectives. PMID- 6901966 TI - [Regimen for young infants]. PMID- 6901967 TI - [Shaping of emotions in young infants]. PMID- 6901968 TI - [Organization of care for infants newly admitted to nurseries]. PMID- 6901969 TI - [Prevention of visual disorders in preschool children]. PMID- 6901970 TI - [Gymnastics for young infants]. PMID- 6901971 TI - [Motor activity and the health of children]. PMID- 6901972 TI - [School studies and the health of schoolchildren]. PMID- 6901973 TI - [Arrangement of the lighting in children's art schools]. PMID- 6901975 TI - [Medical educational advice for the mother on child rearing in the family]. PMID- 6901974 TI - [Hygienic requirements for Pioneer camps]. PMID- 6901976 TI - [Treatment of children frequently ill with acute respiratory infections]. PMID- 6901978 TI - [Electrocardiographic method of examining children with arrhythmias]. PMID- 6901977 TI - [Prevention of acute respiratory viral infections in infants attending nurseries]. PMID- 6901979 TI - [Educational work of nurses]. PMID- 6901980 TI - [Role of the nurse in educating children to hygienic habits]. PMID- 6901981 TI - [Educational activities in the pediatric hospital]. PMID- 6901982 TI - [Organization and carrying out of extracurricular measures on the hygienic education of schoolchildren]. PMID- 6901983 TI - [Mental infantilism]. PMID- 6901984 TI - [Activities of a hospital nurses' council]. PMID- 6901985 TI - [Care of patients with spinal and spinal cord injuries]. PMID- 6901987 TI - [Medical gymnastics in femoral neck fractures]. PMID- 6901986 TI - [Diagnosis and surgical treatment of spinal canal tumors]. PMID- 6901988 TI - [Mechanisms of the therapeutic action of massage]. PMID- 6901989 TI - [Technic of therapeutic massage]. PMID- 6901992 TI - [Bayonet-shaped retractor]. PMID- 6901991 TI - [Modified 4-tailed bandage]. PMID- 6901990 TI - [Role of the nurse in the work of the phlebology office]. PMID- 6901993 TI - [Elastic clamp]. PMID- 6901994 TI - [Medical support for the competition and training sites of the 1980 Olympics]. PMID- 6901995 TI - [Stand for oxygen therapy]. PMID- 6901996 TI - [Use of drugs in aerosol containers]. PMID- 6901997 TI - [Work of the nurse on a medical consultation committee (MCC)]. PMID- 6901998 TI - [Scientific work organization in the activity of a central district hospital]. PMID- 6901999 TI - [Plant agent stimulants]. PMID- 6902000 TI - [Machines for washing needles, syringes, surgical instruments and laboratory glassware]. PMID- 6902001 TI - [Quality day]. PMID- 6902003 TI - [Legends, facts, hypotheses: the drug may be everything]. PMID- 6902002 TI - [Characteristics of the care of acute pancreatitis patients]. PMID- 6902004 TI - [Prevention of complications in chronic cholecystitis]. PMID- 6902005 TI - The politics of health care. PMID- 6902006 TI - Human rights and health care for the developmentally disabled population. PMID- 6902007 TI - Getting organized: a simple recipe for change. Part II. PMID- 6902009 TI - Inside Matsapha: mental health nursing in Swaziland. PMID- 6902008 TI - Michigan Hospital Association attempts to control. PMID- 6902010 TI - Sexual abuse of children. PMID- 6902011 TI - The developmentally disabled--nursing action. PMID- 6902012 TI - Perinatal morbidity and mortality. PMID- 6902013 TI - Perinatal mortality surveys. What value are they? PMID- 6902015 TI - Dental health education for mothers of pre-school children. PMID- 6902014 TI - Travel medicine. PMID- 6902016 TI - The tricyclic antidepressants. PMID- 6902017 TI - Midwives and their training: Second report from the social services committee "Perinatal and Neonatal Mortality", (Chapter 11) PMID- 6902019 TI - Advice services and the health worker--a constructive partnership. PMID- 6902018 TI - The complications of difficult forceps. PMID- 6902020 TI - A pilot study to detect hearing impairment in the young. PMID- 6902021 TI - Teacher training through the National Childbirth Trust. PMID- 6902022 TI - Response and initiative: breast feeding in the community. PMID- 6902023 TI - Rubella immunization in the USA and in Great Britain. PMID- 6902024 TI - Letters from abroad: Kenya. PMID- 6902025 TI - Perinatal and neonatal mortality: House of Commons Social Services Committee - second report. PMID- 6902026 TI - Prenatal education - parentcraft classes. PMID- 6902027 TI - Intractable nasal carriage of methicillin-resistant Staphylococcus aureus. AB - The elimination of a methicillin-resistant strain of Staphylococcus aureus (MRSA) from the nose of a hospital staff member is described. Administration of antibacterial agents and intranasal inoculation of a sensitive strain of Staph. aureus failed to eradicate the MRSA. The MRSA disappeared after removal of the staff member from the hospital environment. PMID- 6902028 TI - In-sevice education can be provided to health care agencies through a community/junior college. PMID- 6902029 TI - One's man's view: peripheral arterial surgery. PMID- 6902030 TI - The years of the child. PMID- 6902031 TI - Preparing children for surgery. PMID- 6902032 TI - Comments by The National Association of Theatre Nurses on Patients first. PMID- 6902033 TI - The implementation of teaching programmes for learners in operating departments. PMID- 6902035 TI - Student nurses in the operating theatre. PMID- 6902034 TI - A sharp reminder. PMID- 6902036 TI - Student nurses in the operating theatre: a choecystectomy. PMID- 6902037 TI - Career opportunities in nephrology nursing. PMID- 6902038 TI - What does an administrator look for in selecting nephrology nursing personnel? PMID- 6902039 TI - Staff nurse position: flexibility and variety gives the staff nurse a choice of many areas of patient care. PMID- 6902041 TI - Home dialysis coordinator. PMID- 6902042 TI - The self care training nurse: moving the renal patient from basic acceptance to competence. PMID- 6902040 TI - Nephrology nurse clinician: the motivations and rewards of patient contact. PMID- 6902043 TI - Nephrology nursing coordinator. PMID- 6902044 TI - Career opportunities in nephrology nursing : the administrator. PMID- 6902045 TI - Preparation and functions of faculty members in a baccalaureate nursing program: academic requirements and instructional techniques for the nursing faculty. PMID- 6902047 TI - The nurse in industry. PMID- 6902046 TI - Career opportunities for the nephrology nurse consultant: hints and experiences from the professional life of a successful nephrology nurse consultant. PMID- 6902048 TI - Renal disease at a glance: analgesic nephropathy : a case study, including symptoms, diagnoses, and prognosis. PMID- 6902049 TI - Nursing and the network: services and requirements of the end-stage renal disease network. PMID- 6902050 TI - A beginning knowledge base for the psychomotor domain. PMID- 6902051 TI - Droppings. PMID- 6902052 TI - Philosophy of school nursing. PMID- 6902053 TI - Community outreach: Part II. PMID- 6902054 TI - On the scene: the community. PMID- 6902056 TI - Educating nurses to reach out. PMID- 6902055 TI - Creating links between hospital and community. PMID- 6902057 TI - Meeting special needs. PMID- 6902058 TI - How to make the audit work. PMID- 6902059 TI - NAQ forum: outreach programs: past, present and future. PMID- 6902060 TI - Outpatient nurses and the community. PMID- 6902061 TI - Staff development via television. PMID- 6902062 TI - Teaching home health care with videotapes. PMID- 6902063 TI - Video taping as a viable teaching strategy in nursing education. PMID- 6902064 TI - Sharing: home sweet home. PMID- 6902065 TI - Medication errors: never borrow medications. PMID- 6902066 TI - Guillain-Barre syndrome: helping the patient in the acute stage. PMID- 6902067 TI - Facial fractures: take a special kind of nursing care. PMID- 6902069 TI - Rabies update. PMID- 6902068 TI - Preventing...and treating...cancer chemotherapy's oral complications. PMID- 6902070 TI - New thinking about parenteral iron supplements. PMID- 6902071 TI - Making every minute count with an esophageal gastric tube airway. PMID- 6902072 TI - Depression: what to do, what to say. PMID- 6902074 TI - Measuring patient stress with the hospital stress rating scale. PMID- 6902075 TI - Understanding and treating hemophilia. PMID- 6902073 TI - Physical reconditioning--Rx for the convalescent patient. PMID- 6902076 TI - Test your knowledge of current nursing practice. Part 5. PMID- 6902077 TI - RNs and NAs working together: two perspectives. PMID- 6902078 TI - Your legal liability as a critical care nurse. PMID- 6902080 TI - Understanding your patient's pain. PMID- 6902081 TI - Digitalis: reducing the risks of toxicity. PMID- 6902079 TI - Sharing: if I can see, you can remember. PMID- 6902082 TI - If your patient's joints hurt, the reason may be osteoarthritis. PMID- 6902083 TI - Cardiac arrest: a crisis for all people. PMID- 6902084 TI - Severely burned patients: anticipating their emotional needs: nursing grand rounds. PMID- 6902085 TI - Defusing the dangers of autonomic dysreflexia. PMID- 6902086 TI - Alcoholic cardiomyopathy: abstinence makes the heart grow stronger. PMID- 6902087 TI - Reducing the side effects of steroid therapy. PMID- 6902088 TI - Food for thought: meeting the nutritional needs of the elderly. PMID- 6902089 TI - Taking the trauma out of nasogastric intubation. PMID- 6902090 TI - Test your knowledge of caring for the stroke patient. PMID- 6902091 TI - Evaluate your patient's level of independence. PMID- 6902092 TI - Vantage point: equal employment opportunities. PMID- 6902093 TI - Saving lives: introduction. PMID- 6902095 TI - The mentally handicapped: a group at risk. PMID- 6902094 TI - The ambulance service. PMID- 6902096 TI - Safety in the NHS. PMID- 6902097 TI - Saving lives at work. PMID- 6902098 TI - Saving lives at Pilkington. PMID- 6902099 TI - First aid in the street and home. PMID- 6902100 TI - Major incident procedures. PMID- 6902101 TI - Flood alert - would you be ready? PMID- 6902102 TI - Saving life--a difficult decision. PMID- 6902103 TI - Not 'just another casualty'. PMID- 6902105 TI - Community care of disturbed adolescents. PMID- 6902104 TI - Health visiting in a changing society. PMID- 6902106 TI - The district nurse as a life-saver. PMID- 6902107 TI - Pictures in nursing: emergency resuscitation. PMID- 6902108 TI - Intensive therapy units. PMID- 6902109 TI - Mother and baby--two lives at stake. PMID- 6902110 TI - Careers in nursing: accident and emergency work. PMID- 6902112 TI - Poisoning. PMID- 6902111 TI - Safe practice in theatre. PMID- 6902113 TI - Assessing levels of consciousness. PMID- 6902114 TI - Faecal elimination: introduction. PMID- 6902116 TI - Care study of a colostomy patient. PMID- 6902117 TI - Management of ulcerative colitis. PMID- 6902115 TI - Normal and abnormal bowel function. PMID- 6902118 TI - Living with a stoma. PMID- 6902119 TI - Carrers in nursing: stoma care nursing. PMID- 6902121 TI - Pictures in nursing: appliance management. PMID- 6902120 TI - Counselling the stoma patient. PMID- 6902122 TI - Community care of the stoma patient. PMID- 6902123 TI - Constipation in children. PMID- 6902124 TI - Constipation. PMID- 6902125 TI - Constipation in pregnancy. PMID- 6902126 TI - Constipation in the elderly. PMID- 6902128 TI - Collection of stool specimens. PMID- 6902127 TI - Constipation in the terminally ill. PMID- 6902129 TI - Colonoscopy. PMID- 6902130 TI - The health professions in Europe. 2. Nurses and midwives. PMID- 6902131 TI - Nursing with the forces: 3. The QARNNS. PMID- 6902132 TI - Maternity rights and employment in the National Health Service. PMID- 6902133 TI - Nursing as a research based profession - some ethical issues. PMID- 6902134 TI - Ergonomics--the team approach. PMID- 6902135 TI - Making work more human: the case for group technology. PMID- 6902136 TI - Safety: reducing the risk of fire. PMID- 6902137 TI - Case history: scrombotoxic poisoning. PMID- 6902138 TI - Organisation theory revisited: is it an essential skill for OH nurses? PMID- 6902140 TI - Occupational first aid. No. 13. New legislation--reactions I. PMID- 6902141 TI - Hazards of treatment with ultraviolet light. PMID- 6902139 TI - Right of reply: organisation theory in occupational health. PMID- 6902142 TI - Looking at problems--a new approach to injury records. PMID- 6902143 TI - Safety: applying TLVs. PMID- 6902144 TI - The ASTMS strategy--will it work? PMID- 6902145 TI - Dead end arguments. PMID- 6902146 TI - Cadmium - working with a poison. PMID- 6902148 TI - Safety: explosions - prevention and control. PMID- 6902147 TI - Looking at health from the consumers' point of view. PMID- 6902149 TI - Fire, mist and vapours. PMID- 6902150 TI - Spouse abuse. PMID- 6902151 TI - Occupational biologic hazards. PMID- 6902152 TI - Employee Education Programs-one aspect of a nurse's expanded role in an occupational health program. PMID- 6902153 TI - Introduction to assessment of the skin. PMID- 6902155 TI - The nurse as a change agent. PMID- 6902154 TI - Knowing the diabetic worker: how diabetics are discovered in industry. PMID- 6902156 TI - Occupation health nurses and collective bargaining: a statement by the American Association of Occupational Health Nurses, Inc. PMID- 6902157 TI - Occupational health nursing: employee mental health. PMID- 6902158 TI - IRB's: are your clients and staff protected? PMID- 6902159 TI - Summary report of the task force to develop implementation plan for two levels of entry into nursing practice. PMID- 6902160 TI - The education/service split: who loses? PMID- 6902162 TI - A course in self-care for rural residents. PMID- 6902161 TI - How independent should independent learning be? PMID- 6902163 TI - Faculty burnout--and some reasons why. PMID- 6902164 TI - Nursing the dying: suggested teaching strategies. PMID- 6902166 TI - Split brain theory: implications for nurse educators. PMID- 6902167 TI - It could happen again. PMID- 6902165 TI - Students participate in the legislative process. PMID- 6902168 TI - Learning to observe. PMID- 6902169 TI - [Ideology of nursing care staff toward the rehabilitation of the elderly sick: validation of an attitude scale]. PMID- 6902170 TI - Doctoral preparation for nurses. PMID- 6902172 TI - An overview of simulation games and comments on their use in baccalaureate nursing education: : a response. PMID- 6902171 TI - An overview of simulation games and comments on their use in baccalaureate nursing education. PMID- 6902173 TI - The invulnerable child. PMID- 6902174 TI - Analysis of student performance ratings. PMID- 6902175 TI - Worth more than money. PMID- 6902176 TI - 'East' is a cold word. PMID- 6902177 TI - Not in front of the children? PMID- 6902179 TI - Occupational health 3: X-ray on the job. PMID- 6902178 TI - Nightmares: terrors lurking in the dark. PMID- 6902181 TI - Marital therapy: uncomfortable feelings. PMID- 6902180 TI - British Diabetic Association camps: a holiday with a difference. PMID- 6902182 TI - Sleeping sickness. PMID- 6902183 TI - Specialist nurse: the case for a cancer nurse. PMID- 6902184 TI - A clinical refresher: back to the grass roots. PMID- 6902185 TI - Nursing care study - alcoholism: the sins of the father.... PMID- 6902187 TI - Living with mother. PMID- 6902186 TI - Light years away from the NHS: a recent course on refugee camps gave invaluable insights to volunteer helpers. PMID- 6902188 TI - A computer system for student nurse allocation during training. PMID- 6902189 TI - A computer-based system for the automatic production of nursing workload data. PMID- 6902190 TI - A child with an infected Spitz-Holter valve. PMID- 6902191 TI - The contraceptive effects of lactation. Failure to appreciate these effects resulted in unnecessary stress for a couple. PMID- 6902192 TI - An attempted suicide. After psychiatric treatment, the patient's mental state improved and he is now attending work regularly. PMID- 6902193 TI - The nursing process and nursing care studies. How the school of nursing can prepare learners for working in wards which have introduced the nursing process. PMID- 6902194 TI - First aid first. PMID- 6902195 TI - Synapse: arrival in paradise. PMID- 6902197 TI - Laurence Dopson interviews Ruth Ashton, the quiet but determined new general secretary of the Royal College of Midwives: the quiet secretary. PMID- 6902196 TI - The national childbirth trust teacher. PMID- 6902198 TI - What risk a home cofinement? PMID- 6902199 TI - Over to you: unit assessment from below. PMID- 6902200 TI - A sore point? PMID- 6902201 TI - A nursing care plan for convalescence following a cerebrovascular accident. PMID- 6902202 TI - Mastectomy and insertion of prosthesis. PMID- 6902203 TI - Breast prostheses in the UK. PMID- 6902204 TI - Oral hygiene and infection. Patients with oral problems can suffer emotionally just as much as they do physically. PMID- 6902205 TI - The nursing process in psychiatry. One of the greatest problems had been convincing staff of the benefits of the nursing process both to them and to their patients. PMID- 6902206 TI - You and your money: pensions. PMID- 6902207 TI - Progress at the poly. PMID- 6902209 TI - Primary health care in Thamesmead - 1. PMID- 6902208 TI - Synapse: a day in Dagua. What a lot we take for granted. PMID- 6902210 TI - Hospitals should do the sick no harm. 7. Urinary tract infection. PMID- 6902211 TI - A new experience. PMID- 6902212 TI - An old, old story. PMID- 6902213 TI - Nursing and human sexuality. PMID- 6902214 TI - Nursing care study: illness - the last refuge of despair. PMID- 6902215 TI - Madness - or just a case of sadness? Psychodrama with a group of psychiatric patients. PMID- 6902216 TI - Nurse and chaplain. PMID- 6902217 TI - Building play skills. PMID- 6902218 TI - Clinical parable: many unhappy returns. PMID- 6902219 TI - Acute ward planning: an alternative approach. PMID- 6902220 TI - Planning a study tour. PMID- 6902221 TI - X-ray anatomy 4. PMID- 6902222 TI - The shape of things to come. PMID- 6902223 TI - Bricks without mortar. PMID- 6902226 TI - Nurses in tabards. PMID- 6902224 TI - Does he take sugar? PMID- 6902225 TI - Nursing care study: a patient with chronic bronchitis, emphysema, cor pulmonale and pulmonary embolism. PMID- 6902227 TI - Fats and heart disease: a point for controversy. PMID- 6902228 TI - Geriatric care: the nurse's contribution to the team. PMID- 6902229 TI - Sources and levels of noise on the ward at night. PMID- 6902230 TI - Problems of extreme weather in Sweden. PMID- 6902231 TI - Primary health care in Thamesmead - 2. PMID- 6902232 TI - Systems of life No 68. Systems and signs: the cardiovascular system - 3. PMID- 6902233 TI - 'And grief itself be mortal.'. PMID- 6902234 TI - On location - 2. The challenge of nursing in suburbia. PMID- 6902235 TI - Nursing care study: care in chronic illness using a Health Profile - 1. PMID- 6902236 TI - Psychological approaches to violence. PMID- 6902237 TI - The working life of the nurse teacher. PMID- 6902239 TI - The pending file. PMID- 6902238 TI - State registration - a ticket to ride. PMID- 6902240 TI - Not-so-goodbye? PMID- 6902241 TI - Coping with grief. PMID- 6902242 TI - Complete nursing care-1. PMID- 6902243 TI - Nursing care study: care in chronic illness using a Health Profile-2. PMID- 6902244 TI - A home delivery in Holland. PMID- 6902246 TI - Natural family planning. PMID- 6902245 TI - Mandibular deformity. PMID- 6902247 TI - Disposable gloves. PMID- 6902248 TI - How should we dispose of our used needles and syringes? PMID- 6902249 TI - Continuous assessment within the King's Health District. PMID- 6902251 TI - Maggie is dead ... they said. PMID- 6902250 TI - Hospitals should do the sick no harm. 8. The infection of wounds. PMID- 6902252 TI - A myth, a model, a necessity. PMID- 6902253 TI - Nurse - could you care more? PMID- 6902255 TI - Complete nursing care - 2. The feelings of the ward sister. PMID- 6902254 TI - Theatre nursing care study: Heller's operation for achalasia of the cardia. PMID- 6902256 TI - Complete nursing care - 2. PMID- 6902257 TI - Complete nursing care - 2. Two student nurses' opinions. PMID- 6902258 TI - Complete nursing care - 2. The view of an NO on night duty. PMID- 6902259 TI - Complete nursing service - 2. Education perspectives from an SNO. PMID- 6902260 TI - Autogenic training. PMID- 6902261 TI - Breastfeeding twins. PMID- 6902262 TI - The resident's role in residential homes for the elderly. PMID- 6902263 TI - Clinical parable: Old Queen Cole. PMID- 6902264 TI - Safety representatives - warts and all. PMID- 6902265 TI - Save the children. PMID- 6902266 TI - Home thoughts. PMID- 6902268 TI - Nursing care study: Congenital dislocation of the hip - 2. PMID- 6902267 TI - Congenital dislocation of the hip - 1. PMID- 6902269 TI - Hormonal influences in lactation. PMID- 6902270 TI - Congenital scoliosis. PMID- 6902271 TI - Where now? A social problem. PMID- 6902272 TI - Where have all the patients gone? PMID- 6902273 TI - Immortality - the American dream - or, what a way to go! PMID- 6902274 TI - District nursing: a sign of the times. PMID- 6902275 TI - District nursing. PMID- 6902276 TI - District nursing: bringing the system home. PMID- 6902277 TI - District nursing: a processed approach to Annie. PMID- 6902278 TI - District nursing: SOS...patients in distress. PMID- 6902279 TI - District nursing: a sore subject. PMID- 6902280 TI - District nursing: new course, new scope, new prestige. PMID- 6902282 TI - When it's a voluntary decision. PMID- 6902281 TI - A question of birth. PMID- 6902284 TI - Lie back and enjoy it. PMID- 6902283 TI - Halfa de League from Barbados! PMID- 6902285 TI - Catherine Hall: confessions of a workaholic. PMID- 6902287 TI - New nursing legislation: from Briggs to eternity. PMID- 6902286 TI - Law and the nurse: why patients must consent to treatment. PMID- 6902288 TI - Plastic surgery: result-a lip to be kissed with relish. PMID- 6902290 TI - Picture quiz: schistosomiasis. PMID- 6902289 TI - Nursing care study. Cleft lip and palate: the boy who wouldn't lie down. PMID- 6902291 TI - Cot death: studying the unknown. PMID- 6902292 TI - An age of intimate concern. PMID- 6902294 TI - The two wheels of freedom. PMID- 6902293 TI - In camera: how much exercise do you get? PMID- 6902295 TI - On your bike! PMID- 6902296 TI - Tobacco and the Third World. The promotion of an epidemic. PMID- 6902297 TI - Delegation: to do or not to do? PMID- 6902299 TI - Specialists in birth. PMID- 6902298 TI - Fairy tale or nightmare? PMID- 6902300 TI - Delirium in old age. Confusing the causes of confusion. PMID- 6902302 TI - Melanoma. PMID- 6902301 TI - Have typhoid, will travel. PMID- 6902303 TI - Anomalies of the newborn. Biochemistry and blood group serology. PMID- 6902305 TI - Let 'adaptable' be the key word. PMID- 6902304 TI - Whipple's pancreaticoduodenectomy: Restless nights. PMID- 6902306 TI - A rare twosome. Monoamniotic twins. PMID- 6902307 TI - Marital therapy: 'you could have a laugh'. PMID- 6902308 TI - Health care in America and England. Crosswinds over the Atlantic. PMID- 6902309 TI - Design and patient care: a chair is a chair, or is it? PMID- 6902310 TI - Stoke Mandeville 2: where there's a will... PMID- 6902311 TI - We are seeking progress. PMID- 6902312 TI - Medical uses of charcoal cloth. PMID- 6902314 TI - Baby mortality: it's not just a question of cash. PMID- 6902315 TI - Time to sit down and talk. PMID- 6902313 TI - The most dangerous day in our lives. PMID- 6902316 TI - Occupational health. 1. Diving into deep water. PMID- 6902317 TI - Marital therapy: losing interest. PMID- 6902318 TI - Calcium. PMID- 6902320 TI - Inflammatory bowel disease: causing problems world wide. PMID- 6902319 TI - Nutrition: eat, drink and be healthy. PMID- 6902321 TI - Schizophrenia: the slow march of knowledge. PMID- 6902322 TI - Nursing care study: Breast cancer: a time for reassurance. PMID- 6902323 TI - Nursing care study. Acute ulcerative colitis: facing up to fear. PMID- 6902324 TI - Under fire from all sides. PMID- 6902325 TI - Baby mortality: getting it right for mother and baby. PMID- 6902326 TI - 'My nurse'--and 'my patient'. PMID- 6902327 TI - Naturopathic clinic: a cocktail of alternative medicines and diet. PMID- 6902328 TI - Students' forum - psychiatry. PMID- 6902330 TI - Occupational health. 2. Dangerous substances at work. PMID- 6902329 TI - Marital therapy: breaking up over a baby. PMID- 6902331 TI - Is Exit the way out? PMID- 6902332 TI - Biochemistry: a protective device. PMID- 6902333 TI - Community nursing. Pressure sores: a sore point at home. PMID- 6902334 TI - Nursing care study. Schizophrenia: silence filled with sound. PMID- 6902336 TI - Nursing is a two-sided coin. PMID- 6902335 TI - The long battle over St Benedict's. PMID- 6902337 TI - Relief from pomposity and paranoia. PMID- 6902338 TI - How can nurses stop smoking? PMID- 6902339 TI - St Joseph's Hospice: death-a part of life. PMID- 6902340 TI - Occupational health 4: clouds of misery. PMID- 6902341 TI - Students' forum: infectious diseases. PMID- 6902342 TI - Nursing process: making a new record. PMID- 6902343 TI - Marital therapy: do you know the one about my mother-in-law? PMID- 6902344 TI - Real-time ultrasound scanning: fitting into the routine. PMID- 6902345 TI - Community nursing. Psychiatric nursing: out of the wards. PMID- 6902346 TI - Nursing care study. Peripheral arterial disease: road to rehabilitation. PMID- 6902347 TI - Will a fine record save the Northern? PMID- 6902348 TI - Childhood cancer: introduction. PMID- 6902349 TI - Childhood cancer. PMID- 6902350 TI - Childhood cancer: the 'double hit' disease. PMID- 6902351 TI - Childhood cancer: common cancers. PMID- 6902352 TI - Childhood cancer: in the balance. PMID- 6902353 TI - Childhood cancer: the nurse's viewpoint. PMID- 6902354 TI - Childhood cancer: a family matter. PMID- 6902355 TI - Childhood cancer: death - the final relief. PMID- 6902356 TI - Some of my best friends have babies. PMID- 6902357 TI - The search for racial equality. PMID- 6902358 TI - How can nurses stop smoking? PMID- 6902359 TI - Occupational health 5: when leaving the job may be too late. PMID- 6902360 TI - Computers: when in France. PMID- 6902362 TI - Down memory lane: a laborious trek. PMID- 6902361 TI - Nursing process: a way to better care. PMID- 6902363 TI - Martial therapy: when two is not company. PMID- 6902366 TI - Nursing care study. All quiet on the Western Front. PMID- 6902364 TI - Cannabis sativa: behind the smokescreen. PMID- 6902365 TI - Picture quiz: leishmaniasis. PMID- 6902367 TI - Double trouble for Smith. PMID- 6902368 TI - Legionnaires' identity parade. PMID- 6902369 TI - Breast self-examination: factors influencing compliance. PMID- 6902370 TI - Husbands as health educators for their wives: a pilot study in breast cancer education. PMID- 6902372 TI - The Richmond Virginia area oncology nurses: a small but dynamic group. PMID- 6902371 TI - Hi-protein nutritional supplement. PMID- 6902373 TI - Exploring nursing issues: cost containment. PMID- 6902374 TI - The ONS-ANA outcome standards for cancer nursing practice: two models for implementation. I. Integrating the standards in a clinically elective oncology nursing course. PMID- 6902375 TI - The ONS-ANA outcome standards for cancer nursing practice: two models for implementation. II. Implementation of the nutrition standard at City of Hope National Medical Center. PMID- 6902376 TI - Professional communications: Part IV the agony and the ecstasy: how to successfully write and publish your paper. PMID- 6902377 TI - The adolescent unit: a holistic approach to cancer management. PMID- 6902378 TI - Defining the scope of nursing practice: actors, criteria and economic implications. PMID- 6902379 TI - Malpractice screening panels: do nurses have a role? PMID- 6902380 TI - [Health care and social welfare following the 8th Congress of the Polish Communist Party]. PMID- 6902381 TI - [We and the profession]. PMID- 6902382 TI - [Health education]. PMID- 6902383 TI - [Internal medicine and nursing]. PMID- 6902384 TI - [Head nurse]. PMID- 6902387 TI - [She loves her profession more than anything else. Interview by Zofia Krzanowska]. PMID- 6902385 TI - [Prevention of an Rh serological incompatibility]. PMID- 6902386 TI - [Psychosocial care on the ward level]. PMID- 6902388 TI - [Health and smoking]. PMID- 6902389 TI - [Blood donors and hemotherapy in Poland]. PMID- 6902390 TI - [How easy it is to discard the nursing cap as junk]. PMID- 6902391 TI - [Balance of developmental age medicine]. PMID- 6902392 TI - [Documentation connected with the functions of a head nurse]. PMID- 6902393 TI - [Infant nursing care]. PMID- 6902395 TI - [Nurse's role in health education]. PMID- 6902394 TI - [Advances in the prevention, diagnosis and treatment of nervous system diseases in children]. PMID- 6902396 TI - [The nurse as a leader and her personality]. PMID- 6902397 TI - [Rabka greets children with a smile]. PMID- 6902398 TI - [Hematogenic preparations and their use]. PMID- 6902399 TI - [Protective vaccination]. PMID- 6902400 TI - [Acute laryngeal dyspnea in children]. PMID- 6902401 TI - [The organization and organizational activity of the Polish Nurses' Association]. PMID- 6902402 TI - [A nurse's work day]. PMID- 6902404 TI - [Physical education and the midwife's profession]. PMID- 6902403 TI - [Professional perfection. The floor nurse]. PMID- 6902405 TI - [Fetal distress, its etiology, manifestations and treatment]. PMID- 6902406 TI - [Diagnosis and therapy]. PMID- 6902408 TI - [Nursing and its XIII-th Olympic games]. PMID- 6902407 TI - [Treatment of obesity in health resorts]. PMID- 6902409 TI - [The great success of a comparatively little known nursing school]. PMID- 6902410 TI - [The nurse's cap should be worn with dignity]. PMID- 6902411 TI - [Homogenic preparations and their use]. PMID- 6902412 TI - [Invasive diseases]. PMID- 6902413 TI - [Are you active in the Polish Nurses' Association?]. PMID- 6902414 TI - [Nursing consultation in child health - operational model]. PMID- 6902415 TI - [Address by Dr. Carlos da Silva Lacaz on 15 March, 1980, as patron of a group of graduates of 1979 of the School of Nursing of the Sao Paulo University]. PMID- 6902416 TI - [Urine testing: great care in collecting the samples]. PMID- 6902417 TI - [Protection of the perineum of the parturient woman and protection of the fetus during the expulsion period of labor]. PMID- 6902418 TI - [The nurse's assisting function as performed in the health centers of the State Secretary of Health of Sao Paulo]. PMID- 6902419 TI - [Position of the patient during surgery and implications for nursing care]. PMID- 6902420 TI - [Current aspects in neuropsychosurgery nursing]. PMID- 6902421 TI - [School libraries and courses for practical nurses in the State of Sao Paulo]. PMID- 6902423 TI - Yes, you can help a sexually abused child. PMID- 6902422 TI - [Observed cardiovascular parameters in patients with infarcts during family visits]. PMID- 6902424 TI - What to watch for with synthetic adrenocortical steroids. PMID- 6902425 TI - When a gaping ulcer spells 'spider bite'. PMID- 6902426 TI - Tuberculosis today. The siege isn't over yet. PMID- 6902427 TI - Why pre-op stoma planning is a must...and how you can make sure it's done right. PMID- 6902428 TI - Dysrhythmia of the month club: why the dramatic change in this ECG? PMID- 6902429 TI - How one nurse came to terms with her patients' prejudice. 'Get your black hands off me!'. PMID- 6902430 TI - Cancer chemotherapy. Those dreaded side effects and what to do about them. PMID- 6902431 TI - Legally speaking: beware: your hospital could turn on you! PMID- 6902432 TI - Let's turn off the soap opera image of nursing! PMID- 6902433 TI - Sex Q and A. Frank answers to your most delicate patient-counseling questions. PMID- 6902434 TI - Sound off: 'Ivory tower' vs. practice: the real split in nursing. PMID- 6902435 TI - Is staffing 'realignment' just another word for 'layoff'? PMID- 6902436 TI - Leadership at work: how to make sure that things get done. PMID- 6902437 TI - Sex Q and A: frank answers to your most delicate patient-counseling questions. PMID- 6902438 TI - Special report: drive for independent practice caused joint practice demise. PMID- 6902439 TI - Pulling your patient through congestive heart failure. PMID- 6902440 TI - Is temporary staffing worth it? PMID- 6902442 TI - Turning your patients - mechanically. PMID- 6902441 TI - The drug interactions we all overlook. PMID- 6902443 TI - Cancer chemotherapy: those dreaded side effects and what to do about them. PMID- 6902444 TI - Dysrhythmia of the month club: are these multifocal PVCs? Don't jump to conclusions! PMID- 6902445 TI - 'Me? I'm just pushing the papers'. Yes, supervisor is a cushy job, once you've handled the streakers, the codes, overcrowding, and death. PMID- 6902447 TI - Culture specimens: how to collect, what to expect. PMID- 6902446 TI - Troubling dilemma for career women: 'How long dare I put off having a baby?'. PMID- 6902448 TI - Opinion exchange: was it abortion? Was there a choice? PMID- 6902449 TI - Indochina moves to main street: exotic diseases you're sure to see more of. PMID- 6902450 TI - Drug therapy today: how to coax maximum pain relief from standard drugs. PMID- 6902451 TI - Legally speaking: think twice before you give advice. PMID- 6902452 TI - Five heads are better than one. PMID- 6902453 TI - Lessons in leadership. PMID- 6902454 TI - Begin ... and then continue. PMID- 6902455 TI - Buyer's guide to education. PMID- 6902456 TI - [Thrombopenic purpura in children]. PMID- 6902457 TI - [Hemophilia]. PMID- 6902458 TI - [Hematology in children: psychological management is necessary]. PMID- 6902459 TI - [Acute leukemia in children]. PMID- 6902461 TI - [Psychological aspects in the management of children with leukemia]. PMID- 6902462 TI - [A child with leukemia; an actual case]. PMID- 6902460 TI - [Erythrocytic hemolytic anemia]. PMID- 6902463 TI - [Pharmacology of diazepam and atropine]. PMID- 6902464 TI - [State Diploma for Nurses and nursing subject examinations]. PMID- 6902466 TI - [Campaign against alcoholism: everybody's business]. PMID- 6902465 TI - [Medical complications of chronic alcoholism]. PMID- 6902467 TI - [Alcoholism and digestive system]. PMID- 6902469 TI - [Alcohol and women : the alcoholic woman]. PMID- 6902471 TI - [The child and alcohol]. PMID- 6902468 TI - [Psychological factors in alcohol-induced disorders]. PMID- 6902470 TI - [Alcoholism: nosological and classification problems]. PMID- 6902474 TI - [Place and role of nurses in alcohology]. PMID- 6902473 TI - [Alcoholism: therapeutic management]. PMID- 6902472 TI - [Alcoholism and work]. PMID- 6902475 TI - [The National Committee for Protection against Alcoholism]. PMID- 6902476 TI - [4 questions apropos of movements of former drinkers]. PMID- 6902477 TI - [Food hygiene. The kitchen and cookery]. PMID- 6902478 TI - [Anesthesia and surgical resuscitation. Long-term preoperative resuscitation]. PMID- 6902480 TI - [Early case finding of excessive alcohol consumption and teaching of physical examination]. PMID- 6902479 TI - [Anesthesia and surgical reanimation. Premedication]. PMID- 6902481 TI - [Aquired immunologic deficiencies]. PMID- 6902482 TI - [Review of the physiological and physiopathological fundamentals of immunology]. PMID- 6902483 TI - [Immunologic reactions to certain drugs]. PMID- 6902484 TI - [Corticotherapy]. PMID- 6902485 TI - [Supervision of corticosteroids]. PMID- 6902487 TI - [Glossary of immunologic terms and diseases]. PMID- 6902486 TI - [Nursing care of a patient with multiple myeloma]. PMID- 6902488 TI - [Preparation of the patient and transfer to the operating theater]. PMID- 6902489 TI - [Hygiene of food and beverages: spices, fruit and vegetables]. PMID- 6902490 TI - Drug-resistant pneumococci. PMID- 6902491 TI - Nurse's medication "errors": a new perspective. PMID- 6902492 TI - The structure of conflict in nurse-physician relations. PMID- 6902493 TI - Commitment to nursing in Columbia. PMID- 6902494 TI - Professional nursing practice in the hospital setting. PMID- 6902495 TI - Values. Part IV--Leading educators believe that the most important learning is the continuing education of educated adults. PMID- 6902496 TI - Systems control: reducing lost central supply charges. PMID- 6902497 TI - Nurses and the malpractice law--Part II. Law for the nurse supervisor. PMID- 6902499 TI - Inside...outside...upside down. PMID- 6902500 TI - Do labor union activities decrease professionalism? PMID- 6902498 TI - The art and science of supervision. Make it specific. PMID- 6902501 TI - Collective action: the basis for professionalism. PMID- 6902502 TI - The professional association and collective bargaining. PMID- 6902503 TI - The director of nursing and collective bargaining. PMID- 6902505 TI - Effective management during labor disputes. PMID- 6902504 TI - Organized nurses view their collective bargaining agent. PMID- 6902506 TI - A 70-day strike by professional nurses. PMID- 6902507 TI - The decertification process. PMID- 6902508 TI - Collective bargaining. Law for the nurse supervisor. PMID- 6902509 TI - Caught in a bind. The art & science of supervision. PMID- 6902510 TI - Negotiating for a change. PMID- 6902511 TI - Perspectives in nursing. Unions and the character of nursing practice. PMID- 6902512 TI - [District health services' proposals]. PMID- 6902513 TI - [American viewpoint: patient care outside of institutions in the 1980s]. PMID- 6902514 TI - [New Norwegian picture series for childbirth education]. PMID- 6902515 TI - [Summer and closed hospital departments]. PMID- 6902516 TI - [Gjovik students' research: patients' need for information and education]. PMID- 6902517 TI - [Health facilities and working environment]. PMID- 6902518 TI - [Occupational health nurses' study days in Bergen]. PMID- 6902519 TI - [That is why we will continue to have nurses in the roentgen department]. PMID- 6902520 TI - [Nursing education]. PMID- 6902522 TI - [Nursing services in psychiatric institutions is nursing's responsibility]. PMID- 6902521 TI - [Norwegian Nurses' Association and specialty nursing]. PMID- 6902523 TI - [Service department informs: regulations on responsibility conditions within institutions for mental health services]. PMID- 6902524 TI - [Health nurses' discussion: reorganization of school health services]. PMID- 6902525 TI - [Research in nursing. 2. Danish Nursing Council's contribution to research in nursing]. PMID- 6902526 TI - [A poor choice over many a weaker group]. PMID- 6902527 TI - [The spiritual need]. PMID- 6902528 TI - [Drug information. Therapeutic main group: agents for the treatment of angina pectoris. 8. Angina pectoris agents with effect on calcium metabolism]. PMID- 6902529 TI - [Statement from the Environmental Administration on increasing Danish preparedness concerning the Barseback works: evacuation functions must be able to be carried out in spite of health risks]. PMID- 6902530 TI - [Interview with the chairman of the Committee for the Aged: a policy for the elderly which is not concerned with the aged. Interview by Soren Palsbo]. PMID- 6902531 TI - [Danish Nursing Council at the start of the 1980s. 1. We found a structure which can also function in adverse times. Interview by Peter Hjorth]. PMID- 6902533 TI - [Once parents hit a crying child]. PMID- 6902532 TI - [A new series of publications from the Danish Hospital Institute]. PMID- 6902534 TI - [Does society want a well-educated nurse?]. PMID- 6902536 TI - [A work which should not come to a standstill]. PMID- 6902535 TI - [Nurse-educated nursing home administrator undermines Danish Nursing Council's right to negotiate: a matter which is a sign of professional bankruptcy]. PMID- 6902538 TI - [Research in nursing: direct action research becomes a book on clinical nursing. Interview by Inger Rosenkvist]. PMID- 6902537 TI - [Help in rehabilitation of handicapped children--from the parents' viewpoint: the entire family is handicapped]. PMID- 6902539 TI - [Drowning and hypothermia: results are good with timely instituted therapy]. PMID- 6902540 TI - [Drug information. Therapeutic main group: agents for the treatment of angina pectoris. 9. Angina pectoris agents with effect on calcium metabolism]. PMID- 6902542 TI - [Danish Nursing Council at the start of the 1980s. 2. Decentralization has contributed towards increased activities]. PMID- 6902541 TI - [Nursing research. Nursing process as introduced to new students]. PMID- 6902543 TI - [From one colleague to another: anesthetic gases and their effect on the working environment]. PMID- 6902544 TI - [Framework time plan for activities concerning negotiations in 1980]. PMID- 6902545 TI - [Sexuality and cohabitation during pregnancy and after childbirth: problems in cohabitation often appear first as sexual problems]. PMID- 6902546 TI - [Nursing home matters in the town of Ulfborg-Vemb: nurse maintains professional requirements despite underhandedness]. PMID- 6902547 TI - [Nursing home conditions in Denmark: many nursing homes have insufficient staff]. PMID- 6902548 TI - [Savings all the way down]. PMID- 6902549 TI - [Danish Nursing Council on training of nursing home aides: training of new groups increasingly pressed by nurses]. PMID- 6902550 TI - [Danish Nursing Council at the start of the 1980s. 3. Use of representatives in the action for already gained benefits. Interview by Soren Palsbo]. PMID- 6902551 TI - [Nursing research. Keys to individualized nursing care]. PMID- 6902552 TI - [Enuresis--involuntary urination in children: a more extensive disorder than one realizes]. PMID- 6902553 TI - [Drug information. Therapeutic main group: agents for the treatment of angina pectoris. 10th and last part. 4. Other angina pectoris agents]. PMID- 6902554 TI - [Year of the Child headquarters: report from the Year of the Child]. PMID- 6902555 TI - [Danish Nursing Council's president at opening of congress: nursing shortage may take hold seriously]. PMID- 6902556 TI - [Nurses will get down to it in the 1980s with courage, strength and endurance]. PMID- 6902557 TI - [Danish Nursing Council's president on economics in the health care sector: the same excellence cannot prevail with reduced personnel]. PMID- 6902558 TI - [Activity of the kallikrein-kinin system of blood and microcirculatory disorders in ischemic heart disease]. PMID- 6902559 TI - Prekallikrein (Fletcher factor) deficiency in clinical disease states. PMID- 6902560 TI - [Inservice education]. PMID- 6902562 TI - [Educational broadcasting offerings: tough answers and questions on handicapped, among others]. PMID- 6902561 TI - [National and local regulations for nursing instructor services in senior high schools]. PMID- 6902563 TI - [Will we have quality or quantity in the education of pediatric nursing?]. PMID- 6902564 TI - [Education - in the form of thoughts]. PMID- 6902565 TI - [Qualifications for laboratory assistants who have had a teachers' education]. PMID- 6902566 TI - [The National Committee on Equality]. PMID- 6902567 TI - [Employment conditions of nursing instructors]. PMID- 6902568 TI - [County council in Orebro extends its research program with health care research]. PMID- 6902570 TI - [Women and professions]. PMID- 6902571 TI - [To work professionally. Interview by Lena Andersson-Svensson]. PMID- 6902569 TI - [Team work in education]. PMID- 6902572 TI - [There you are, in the middle of life--experiences of a pediatric nurse instructor]. PMID- 6902573 TI - [I, myself]. PMID- 6902574 TI - [Rearing children]. PMID- 6902575 TI - [The future of the cross organization activities]. PMID- 6902576 TI - [Tuberculosis--today]. PMID- 6902577 TI - [Experience report of a working period in psychogeriatrics. 3. The condition of employees in the units]. PMID- 6902578 TI - [Once again burns]. PMID- 6902579 TI - [Quality improvement in nursing care]. PMID- 6902580 TI - [Children with cardiovascular disorders]. PMID- 6902581 TI - [Children with congenital heart defects, their parents and the hospital]. PMID- 6902582 TI - [Central Council for Public Health. 2d Interim Advice on development of nursing education]. PMID- 6902583 TI - Studies on porcine pancreatic elastase activity. I. Radioimmunoassay of porcine pancreatic elastase. AB - An improved method of radioimmunoassay was devised to offer a successful formula for determining blood concentration of elastase. With porcine pancreatic elastase as the antigen, rabbits were immunized to obtain antiserum. Iodinated elastase labeled by the chloramine-T procedure using 131I (or 125I) had a specific activity of 200-300 mCi/mg. The double antibody method was used for BF separation. While the usual method of radioimmunoassay was not always successful in obtaining accurate serum concentration of elastase, the use of diisopropyl fluorophosphate (DFP) was able to eliminate the disturbing influence of intra serious inhibitors, alpha 1-AT and alpha 2-M, eventually producing satisfactory results. With the use of DFP, the elastase standard curve and the porcine serum dilution curve had a statistically significant correlation; precision and recovery were both satisfactory; cross-reactivity of the antiserum with trypsin and chymotrypsin was less than 0.001%. The minimal detectable concentration of elastase was 5 ng/ml, and the range of normal fasting porcine serum level was 70 100 ng/ml. PMID- 6902584 TI - Nursing-its diversified roles: spotlight on nursing directors. PMID- 6902585 TI - Test your knowledge: blood transfusions. PMID- 6902586 TI - OR symposium: Part II. PMID- 6902588 TI - Preoperative care of the pediatric patient. PMID- 6902589 TI - Test your knowledge: effective verbal communication. PMID- 6902587 TI - Orthopedic nursing: where have all the orthopedic nurses gone? PMID- 6902590 TI - Legal responsibility for nursing negligence. PMID- 6902591 TI - Cataract: the changing scene. PMID- 6902593 TI - Orthopedic nursing: to be involved or not to be involved: no longer the question. PMID- 6902592 TI - Surgery safari - a preoperative tour. PMID- 6902594 TI - Clinical orientation by objectives. PMID- 6902595 TI - The establishment and development of an occupational health service in hospitals and community service. PMID- 6902596 TI - Work and health. PMID- 6902598 TI - Educational opportunities for the baccalaureate seeking registered nurse. PMID- 6902597 TI - Viewpoint: Nurse dedicated to patients defeats union; "Nurse dedicated to whom?". PMID- 6902599 TI - Entry level into nursing practice. PMID- 6902600 TI - Nursing with self-esteem. PMID- 6902601 TI - [Civil employees have most to lose with social contract]. PMID- 6902602 TI - [Nurses reactivate: back to nursing care after many years of working at home]. PMID- 6902603 TI - [Ulla found a job immediately following the course]. PMID- 6902604 TI - [Tierp Project. Despite underestimation of problems at start work functions during the day]. PMID- 6902605 TI - [National Committee for LPV-proposals established: mentally recovered addicts need not be admitted compulsorily to a mental hospital]. PMID- 6902606 TI - [Trial in Lund: entirely new professional role for hospital managers]. PMID- 6902607 TI - [Questions on employee funds: does nursing get better working conditions?]. PMID- 6902608 TI - [Laboratories computerize--various experiences among staff: positive in Huddinge, negative in Danderyd]. PMID- 6902609 TI - [Tierp Project. We in the profession have never had any influence]. PMID- 6902611 TI - [More information to lessen anxiety/fear]. PMID- 6902610 TI - [Tierp Project. Improved personal communication and less work duplication]. PMID- 6902612 TI - [Does the nurse get sufficient education in technology?]. PMID- 6902614 TI - [Education important for professional activities]. PMID- 6902613 TI - [Large-scale data system explained]. PMID- 6902615 TI - [Research nurses will have own facility]. PMID- 6902616 TI - [Primary health care must expand]. PMID- 6902617 TI - [Here one invests so that children can thrive]. PMID- 6902618 TI - [Proposal on psychiatry policy: nurse's role clarified]. PMID- 6902619 TI - [Personnel manages nursing care development in Jonkoping]. PMID- 6902620 TI - [A stake in comprehensive health care research]. PMID- 6902621 TI - [Debate on Cambodia articles]. PMID- 6902622 TI - [Conflict--how does it affect us?]. PMID- 6902623 TI - [Midwives resign: we won't accept not to have any more holidays!]. PMID- 6902624 TI - [Semper persists: artificial feeding in Turkey via baby bottle]. PMID- 6902625 TI - [Professional and organizational problems dominate delegates' meeting]. PMID- 6902626 TI - [Theme day on comprehensive health care research: nurses have key role]. PMID- 6902627 TI - Primary nursing - what does it all mean? PMID- 6902628 TI - Open your heart and your home - be a foster parent. PMID- 6902629 TI - [State of the human kallikrein-kinin system indices during artificial ventilation with a helium-oxygen mixture under geneal anesthesia]. PMID- 6902631 TI - In vitro antimicrobial susceptibility of Salmonellae from animals in Louisiana. AB - A total of 56 Salmonella isolates from animals were tested for susceptibility to 12 antimicrobial agents by the standard disk diffusion and mirodilution methods. All isolates were susceptible to gentamicin, tobramycin, amikacin, chloramphenicol, crimethoprim and sulfonamide, colistin, and nitrofurantoin. Isolates were most frequently resistant to tetracycline (50%) and kanamycin (36%). A low prevalence of resistance to ampicillin (16%), carbenicillin (16%), and cephalothin (4%) was found. The differences in susceptibility results between the two methods were minor. PMID- 6902630 TI - Prophylactic antibiotics in common dog bite wounds: a controlled study. AB - A double-blind prospective study of 98 patients was carried out, but 57 (58%) returned for follow-up and form the basis of this report. Wound irrigation and debridement were found to be important in reducing infection. Hand wounds were most likely to become infected; face and scalp wounds were at low risk. Puncture wounds became infected more often than did lacerations. Suturing wounds did not increase the likelihood of infection except on the hand, where the data were equivocal. Prophylactic penicillin decreased the incidence of infection in high risk wounds; there was no difference in low-risk wounds. Cultures of wounds showed many different organisms but were of no predictive value. Pasteurella multocida was found very rarely. Staphylococcus aureus accounted for 10% of all infections, a finding which makes use of a penicillinase-resistant penicillin logical. PMID- 6902633 TI - Staff nurses describe frustrations, offer suggestions. PMID- 6902632 TI - House retains current ANA structure. PMID- 6902634 TI - Nursing leaders reflect on the profession's future. PMID- 6902635 TI - Providing health care in jail has its rewards. PMID- 6902636 TI - Paying women less is one more way to exploit them. PMID- 6902637 TI - Proposed design for practice component of ANA. PMID- 6902638 TI - Survey shows a million RNs employed. PMID- 6902639 TI - Sulfamethoxazole- trimethoprim versus ampicillin in treatment of acute invasive diarrhea in adults. AB - Twenty-seven Navajo adults with moderate to severe acute inflammatory diarrhea were hospitalized and randomly given ampicillin or sulfamethoxazole-trimethoprim. All patients had invasive diarrhea as defined by sheets of fecal leukocytes, seen on methylene blue wet-slide preparations, and significant clinical symptoms, including postural hypotension from dehydration or fever (temperature greater than 100 degrees F [or 37.8 degrees C]). Patients were followed daily for 5 days in the hospital. Responses of symptoms in all 13 patients who were given sulfamethoxazole-trimethoprim were comparable to or better than those 14 patients randomly assigned to receive ampicillin. Nineteen (73%) of the 27 patients had culture-proven shigellosis, 6 of whom had ampicillin-resistant Shigella isolates. All isolates were susceptible to sulfamethoxazole-trimethoprim in vitro. The eight patients with culture-proven shigellosis treated with sulfamethoxazole trimethoprim responded as well as the eight patients with ampicillin-susceptible infections treated with ampicillin. Three of the eight patients successfully treated with sulfamethoxazole-trimethoprim had ampicillin-resistant organisms. The three patients with ampicillin-resistant organisms who were treated with ampicillin appeared to do less well; one was a clinical and bacteriological failure at 72 h and subsequently improved after sulfamethoxazole-trimethoprim therapy. As predicted by in vitro susceptibility studies and by studies in children, sulfamethoxazole-trimethoprim was highly effective in treating adult patients with shigellosis and appears to be the treatment of choice in areas where ampicillin resistance among Shigella is common. PMID- 6902640 TI - Defective killing of enterococci: a common property of antimicrobial agents acting on the cell wall. AB - We tested the ability of antimicrobial agents that act on the cell wall to kill enterococci and found defective killing (a minimal bactericidal concentration/minimal inhibitory concentration ratio of greater than or equal to 32) with both beta-lactams (penicillin G and cephalothin) and non-beta-lactams (vancomycin, cycloserine, and bacitracin). Our results indicate that the resistance of enterococci to antimicrobial killing spans the spectrum of agents known to inhibit cell wall synthesis and suggest that the mechanism responsible for enterococcal resistance to killing by these drugs may be a defective autolytic enzyme system. PMID- 6902641 TI - Nurse, what are you all about? PMID- 6902642 TI - Neurological aspects of rehabilitation Part 2: Spinal cord injury. PMID- 6902643 TI - Stimulatory effect of lysophosphatidic acids on uterine smooth muscles of non pregant rats. AB - Lysophosphatidic acids stimulated isolated uterine smooth muscle dose dependently. The contractions were not reduced by pretreatment with atropine or an anti-5-hydroxytryptaminic agent. The potency depended on the nature of the acyl chain in the molecule. Of the compounds with a saturated fatty acyl group tested, the most effective were myristoyl- and lauroyl-lysophosphatidic acid. In a series of unsaturated lysophosphatidic acids, the potency increased with the number of cis double bonds in the acyl chain, and linolenoyl-lysophosphatidic acid was the most active. When injected intravenously, these compounds induced an immediate rise in blood pressure and intrauterine pressure, like prostaglandin F2 alpha: The order of potency of their effects on the intact uterus was consistent with that of their effects on isolated uterine smooth muscle, but not with that of their hypertensive effects in rats. PMID- 6902644 TI - Treatment of staphylococcal infections. PMID- 6902645 TI - Staff involvement in the problem-solving and decision-making processes. PMID- 6902647 TI - Worth noting: Australian volunteers abroad. PMID- 6902646 TI - Flashback, June, 1940. PMID- 6902648 TI - Tonsillectomy - current concepts and nursing care. PMID- 6902649 TI - The patient in hospital: actors in an anxious play. PMID- 6902650 TI - Caring in nursing - are we being side-tracked? PMID- 6902651 TI - Neonatal hypoglycaemia: a potential cause of brain damage? PMID- 6902652 TI - Which tool for measuring quality of care? PMID- 6902653 TI - The Federation. Royal Australian Nursing Federation Annual Report May 1979 - April 1980. PMID- 6902654 TI - Nursing in a male-dominated society. PMID- 6902656 TI - Put yourself in your child's place. PMID- 6902655 TI - Total family involvement. PMID- 6902657 TI - A flaming nuisance: thermal injuries. PMID- 6902659 TI - The pre-schooler. PMID- 6902658 TI - Hot-line electricity. PMID- 6902660 TI - Oops! PMID- 6902661 TI - Those lollies tasted nice. PMID- 6902662 TI - The explorer. PMID- 6902663 TI - Venomous bites and vitamin C status. PMID- 6902664 TI - Women sport and feminism. PMID- 6902665 TI - World health. PMID- 6902666 TI - Pressure areas. PMID- 6902667 TI - What causes accidents? PMID- 6902668 TI - Measurement of protein synthesis in rat lungs perfused in situ. AB - Compartmentalization of amino acid was investigated to define conditions required for accurate measurements of rates of protein synthesis in rat lungs perfused in situ. Lungs were perfused with Krebs-Henseleit bicarbonate buffer containing 4.5% (w/v) bovine serum albumin, 5.6mm-glucose, normal plasma concentrations of 19 amino acids, and 8.6-690mum-[U-(14)C]phenylalanine. The perfusate was equilibrated with the same humidified gas mixture used to ventilate the lungs [O(2)/CO(2) (19:1) or O(2)/N(2)/CO(2) (4:15:1)]. [U-(14)C]Phenylalanine was shown to be a suitable precursor for studies of protein synthesis in perfused lungs: it entered the tissue rapidly (t((1/2)), 81s) and was not converted to other compounds. As perfusate phenylalanine was decreased below 5 times the normal plasma concentration, the specific radioactivity of the pool of phenylalanine serving as precursor for protein synthesis, and thus [(14)C]phenylalanine incorporation into protein, declined. In contrast, incorporation of [(14)C]histidine into lung protein was unaffected. At low perfusate phenylalanine concentrations, rates of protein synthesis that were based on the specific radioactivity of phenylalanyl-tRNA were between rates calculated from the specific radioactivity of phenylalanine in the extracellular or intracellular pools. Rates based on the specific radioactivities of these three pools of phenylalanine were the same when extracellular phenylalanine was increased. These observations suggested that: (1) phenylalanine was compartmentalized in lung tissue; (2) neither the extracellular nor the total intracellular pool of phenylalanine served as the sole source of precursor for protein; (3) at low extracellular phenylalanine concentrations, rates of protein synthesis were in error if calculated from the specific radioactivity of the free amino acid; (4) at high extracellular phenylalanine concentrations, the effects of compartmentalization were negligible and protein synthesis could be calculated accurately from the specific radioactivity of the free or tRNA-bound phenylalanine pool. PMID- 6902670 TI - Familial discoid lupus erythematosus associated with heterozygote C2 deficiency. AB - Two siblings with chronic discoid lupus erythematosus and several family members were found with heterozygous C2 deficiency. An association with histocompatibility markers HLA-B18 and HLA-Dw2 was demonstrated, and the slow allotype of factor B was present. Linkage studies in this family suggested a close linkage between the C2 deficiency gene and genes coding for B18, Dw2, and BfS antigens. One HLA-ACB/DBf recombinant was observed showing closer linkage between HLA-D and Bf than between HLA-B and Bf. PMID- 6902671 TI - In vitro preparation of elastin--triglyceride complexes. Fatty acid uptake and modification of the susceptibility to elastase action. PMID- 6902672 TI - Assessing the outcomes of cancer patients in a home nursing program. PMID- 6902669 TI - Immune complexes in Sjogren's syndrome. AB - Sera from 48 patients with Sjogren's syndrome were examined for immune complexes by the Raji cell assay. There was no correlation between levels of immune complexes and the degree of lymphocytic infiltration of the labial salivary glands. Serum complement levels were normal. Five patients were serially followed during the development of pseudolymphoma or malignant lymphoma. Immune complex levels in 4 of the 5 patients were generally unchanged throughout the illness and did not parallel disease activity, rheumatoid factor, or SS-A and SS-B concentrations. Possible roles for immune complexes in Sjogren's syndrome are discussed. PMID- 6902673 TI - Assessment of nausea and vomiting in cancer patients undergoing external beam radiotherapy. PMID- 6902674 TI - History and development of cisplatin in the management of malignant disease. PMID- 6902675 TI - Cancer audit: how the quality of care improves the quality of life. PMID- 6902677 TI - Toxicity of anticancer drugs used in children. PMID- 6902676 TI - Research highlights: a study in cancer control. PMID- 6902678 TI - Cancer nursing and the law: legislating "patients' rights". PMID- 6902680 TI - INA defends Illinois Nursing Act in court. PMID- 6902681 TI - Inhibition of rat liver isoleucyl-tRNA formation by microsomal membrane and the partial prevention of this inhibition by spermine. PMID- 6902679 TI - [New methods and Czechoslovak kits for the estimation of trypsin, chymotrypsin and elastase (author's transl)]. PMID- 6902682 TI - School nursing-a personal view. PMID- 6902684 TI - Abuse of old people. PMID- 6902683 TI - The gaslight phenomenon. PMID- 6902685 TI - The battered wife. PMID- 6902686 TI - Care study: one man and his leg: the missing link. PMID- 6902687 TI - Mode of action of protein synthesis initiation factor eIF-1 from rabbit reticulocytes. PMID- 6902688 TI - Progesterone-binding properties of the microsomal fraction from chick oviduct. AB - Progesterone binds to specific high-affinity and limited-capacity binding sites of chick-oviduct microsomes of estrogen-primed chicks. The dissociation constant is 2 x 10(-9) M (range 1.6--3.0) and the number of binding sites 500 femtomoles/mg microsomal protein (range 464--551). Treatment of the estrogen primed chicks by progesterone had no apparent effect on the progesterone-binding capacity or affinity. Competition studies showed that testosterone, R-5020, Org 2058, D-norgestrel, 5 alpha-dihydrotestosterone and R-2323 were effective competitors of progesterone, in that order, whereas cortisol, estradiol and estrone exhibited only minimal displacement. No displacement of microsome-bound [3H]progesterone was found with fenoterol or prostaglandin F2 alpha. No high affinity progesterone-binding sites were found in the microsomal fractions of liver, muscle, intestine or brain. On the basis of steroid-binding affinity and steroid-specificity determinations, the microsomal progesterone-binding components seem to be different from the progesterone receptor previously described in chick oviduct cytosol. PMID- 6902690 TI - [Psychophysiology of dreaming and neurosis therapy: the functional state-shift model, a synopsis (author's transl)]. PMID- 6902689 TI - [Electrophysiologic investigations in a family with malignant hyperthermia (author's transl)]. AB - The value of the quantitative electromyogram in the detection of subclinical myopathic signs was tested in a family consisting of 11 members, one of them showing a Malignant Hyperthermia crisis. Furtheron an in vitro contracture test and an ATP-test was performed and the Serum CPK and the isoenzyme in serum and muscle examined. The following conclusions were taken: 1) Although unspecific pattern (in 5 cases more than 12% polyphasic potentials were found, one of them showing a reduction of the mean duration of 30%) the electromyography is a good but not absolutely certain indicator of subclinical myopathic signs in Malignant Hyperthermia. 2) The exclusion of M.H. risk is not possible using a single test. 3) The diagnostic value of not invasive methods, as the electromyography is of special importance. The diagnostic use of many M.H. tests seems necessary. PMID- 6902691 TI - [Prognosis in patients with cerebral ischemia treated with short term anticoagulant therapy -- a controlled trial (author's transl)]. PMID- 6902692 TI - [Metabolism of noradrenaline and endogenous depression (author's transl)]. PMID- 6902693 TI - [Depressive syndromes in the course of schizophrenia (author's transl)]. PMID- 6902695 TI - [Anemia]. PMID- 6902694 TI - [Social and family relationships of depressive patients (author's transl)]. PMID- 6902696 TI - [Need for gynecological examinations for all women during their active ovarian period]. PMID- 6902698 TI - [Social security in the framework of the European Economic Community]. PMID- 6902697 TI - [The psychiatric nurse: use of psychological tests in adult psychiatry]. PMID- 6902699 TI - An integrated approach to training in research methodology and statistics. PMID- 6902700 TI - Preparation of school-age children for surgery: a program in preventive pediatrics--philippines. PMID- 6902702 TI - Loneliness: measuring the abstract--II. PMID- 6902701 TI - A study of white males with hypertension: manifest needs and self actualization. PMID- 6902703 TI - Social work and community psychiatric nursing--a review. PMID- 6902704 TI - Prediction of nursing requirements from patient characteristics--II. PMID- 6902705 TI - The nursing process: a problem-solving approach to patient care. PMID- 6902706 TI - Epidemiological study of a body temperature in patients in a teaching hospital. PMID- 6902707 TI - Nursing abroad in an undergraduate programme. PMID- 6902708 TI - Development of maternal and child health services in Israel. PMID- 6902709 TI - Nursing: thoughts on nursing service and identification of the service offered. PMID- 6902710 TI - The migration of nursing personnel. PMID- 6902711 TI - Meeting the immunological challenge--Rush Presbyterian-St. Luke's Medical Center symposium. PMID- 6902712 TI - Physiology of the immune system. PMID- 6902713 TI - Immunosuppression, autoimmunity, and hypersensitivity. PMID- 6902715 TI - Anaphylaxis and drug reactions: guidelines for detection and care. PMID- 6902714 TI - The immunologic assessment: a nursing focus. PMID- 6902716 TI - Plasmapheresis: current research and success. PMID- 6902717 TI - The patient with systemic lupus erythematosus: prototype of autoimmunity. PMID- 6902718 TI - The intrigue and challenge of Goodpasture's syndrome. PMID- 6902719 TI - Right ventricular infarction: recognition, treatment, and nursing considerations. PMID- 6902720 TI - Convulsive disorder mimicked by prolonged asystole and cured by permanent pacing. PMID- 6902721 TI - Obesity--a new approach to an old person. PMID- 6902722 TI - The hyperacute phase of posterolateral myocardial infarction. PMID- 6902723 TI - Angina pectoris in the absence of coronary artery disease. PMID- 6902724 TI - C NMR spectra of streptolydigin, tirandamycin, and related degradation products. AB - Absorptions of the 32 carbon atoms of streptolydigin, a 3-acyltetramic acid, have been assigned in its C NMR spectrum, as have the adsorptions of triandamycin and related degradation products. Methods employed in assigning the individual carbons include off-resonance decoupling, and comparison studies with appropriate model compounds. PMID- 6902725 TI - Degradation of fibronectin by human leukocyte elastase. Release of biologically active fragments. AB - We have identified the biological activity of three polypeptides released by limited proteolysis of human plasma fibronectin by leukocyte elastase. A Mr = 140,000 peptide contains cell-spreading activity; a Mr = 60,000 peptide mediates binding to denatured collagen (gelatin), and a Mr = 29,000 peptide contains glutaminyl residues responsible for the transglutaminase (blood coagulation factor XIIIa)-catalyzed incorporation of amines. More extensive proteolysis yielded numerous peptides, including a Mr = 40,000 peptide derived from the Mr = 60,000 peptide which retains gelatin-binding activity. Quantification of the gelatin-binding peptides is consistent with two binding sites per dimeric fibronectin molecule of Mr = 440,000. Both Mr = 60,000 and 40,000 gelatin-binding peptides were enriched with half-cystine residues, containing 28 and 25, respectively, but devoid of cysteine. This, coupled with the electrophoretic behavior of both peptides, was consistent with the presence of intramolecular disulfide bonds in the gelatin-binding domain. Intact fibronectin contains 1 free cysteine residue/monomer, as recently described. This cysteine reacts with 5,5' dithiobis(2-nitrobenzoic acid) very slowly under nondenaturing conditions but rapidly when fibronectin is denatured. The free cysteine is located in the Mr = 140,000 peptide. While the Mr = 40,000 and 60,000 gelatin-binding peptides bind to gelatin with an affinity about 30-fold and 5-fold less than intact fibronectin (based on a monomeric fibronectin Mr = 220,000), neither gelatin-binding peptide supports spreading of fibronectin-deficient test cells on gelatin or tissue culture plastic substrates. The purified Mr = 140,000 peptide supported cell spreading on plastic, retaining about one-half of the spreading activity of intact fibronectin on a weight basis. These data confirm recent results, suggesting multiple, protease- resistant domains with discrete biological functions within fibronectin. Our results, together with established data, suggest a model for the location of the transglutaminase-reactive glutaminyl residues, gelatin binding, and cell-adhesive domains in fibronectin. The release of univalent, biologically active fibronectin fragments by elastase, a major physiologically released inflammatory protease of human leukocytes, suggests a new potential mechanism for alteration of cell connective tissue interactions at sites of inflammation in vivo. PMID- 6902726 TI - Activation of human leukocyte elastase activity by excess substrate, hydrophobic solvents, and ionic strength. PMID- 6902728 TI - Theory development and its relevance for nursing. AB - If the nursing profession is to continue to make advancements, it must envision new ways of perceiving the phenomena peculiar to nursing and must propose meaningful explanations for these perceptions. The approaches to nursing theory development are spread out over a theory practice continuum, ranging from Martha Roger's pure scientific approach to Dickoff and James' practice approach. The very existence of this continuum signifies nursing's problem in deciphering the nature of the relationship between nursing theory and nursing practice. While the development of nursing theory is essential to the establishment of a theoretical body of knowledge unique to nursing as a science, this must not be its only function. Theory development must be integrated with nursing practice if the profession is to survive and grow. PMID- 6902727 TI - Nephritic factor of the classical pathway of complement: immunoglobulin G autoantibody directed against the classical pathway C3 convetase enzyme. AB - A factor, functionally characterized by its capacity to stabilize the normally labile classical pathway C3-converting complex of the classical pathway of complement, has been isolated from the serum of one patient with a case of acute glomerulonephritis, subsequent to a cutaneous infection. The factor confers long lived stabilization of classical pathway C3 convertase complexes formed both in the solid (sensitized sheep erythrocytes bearing activated C1 and the classical pathway C3 convertase) and fluid phase. The half-life of such stabilized C3 cleaving enzymes extended beyond several hours at 37 degrees C. The stabilizing activity was associated with a protein fraction immunochemically identified as immunoglobulin (Ig)G, a sizeable population of which exhibited a gamma chain of 60,000 daltons. The IgG-associated stabilizing activity was found to bind to the classical pathway C3 convertase enzyme via a fragment bearing the antigen-binding site of the molecule [F(ab)(2) and F(ab)]. Such binding was demonstrable for classical pathway and not for alternative pathway C3 convertase. Thus, the stabilizing factor behaves like an autoantibody to the C3-converting complex of the classical pathway of complement. The binding of the antibody to the enzyme affords protection of the latter against decay-degradation. By analogy with the nephritic factor of the alternative pathway situation where IgG autoantibodies specifically bind to alternative pathway C3 convertase enzymes and protect them from degradation, the functionally unusual IgG in our patient was designated as the nephritic factor of the classical pathway. Indirect evidence suggests that nephritic factor of the classical pathway-IgG might be of the IgG3 subclass. PMID- 6902729 TI - Obtaining access to data sources: an exploration of method, problems and possible solutions. AB - A method, route and problems relating to the gaining of access to research data or respondents is discussed. In seeking permission to gather data from patients and staff in Scottish psychiatric hospitals, using Flanagan's Critical Incident Technique, a number of problems were encountered, viz. (i) the varying admnistrative levels to which the first formal request for entry had to be made; (ii) the varying routes which had to be followed in order to gain permission, and (iii) the time taken to obtain access to data sources. The problems, their possible consequences, and a number of long and short term recommendations are made. If implemented, these may go some way toward minimizing the difficulties associated with gaining access to data sources. The long term recommendations, including improved nurse representation on existing research and ethical committees, are directed to those who shape and influence policies relating to research practice generally. The short term recommendations are directed to the nurse researcher who is seeking access to field sites, with a view to minimizing problems relating to this aspect of planning and carrying out research activity. PMID- 6902731 TI - Setting performance goals in geriatric nursing. AB - Behavioural techniques are increasingly being applied in the geriatric field as part of a broader emphasis on psychological and social treatments in the care of the elderly. The nurse is in the best position to analyse a patient's performance and manage an intervention programme; however, some nurses have had little experience of autonomously diagnosing problems and setting performance goals. The authors argue that it is important to set such goals and give examples of how performance may be objectively specified, prerequisites made explicit, criteria for success defined and the consequences of goal attainment or non-attainment discussed with those most concerned. A complex situation drawn from the geriatric setting which was used as part of a teaching workshop to help nurses define suitable targets for intervention is described in the Appendix. PMID- 6902730 TI - Organization development in a psychiatric hospital: creating desirable changes. AB - The organization of the way in which hospitals and hospital staff provide a service to patients is obviously of critical importance to their effectiveness, yet it is clear that rigidities and inappropriate and ineffective procedures frequently intrude. It is commonly held that changing hospitals as organizations is difficult to acomplish, and indeed, reported attempts at such change reflect this. The project reported here was a successful attempt at changing a number of different aspects of the culture of a psychiatric hospital which included managerial practices and structure, aspects of patient care, multidisciplinary team work, and staff development. The present paper concentrates on some specific outcomes at ward level. The general pattern for bringing about change involves the collection of (valid) data and then feeding this back to the staff involved so that they can take appropriate action. The data discussed here concerned ward nursing staff's attitude to the 'climate' of the hospital, their job satisfaction and aspects of patient care. This was fed back to nursing, managerial and medical staff, and action plans were agreed to overcome the difficulties highlighted. Outcomes have included the production of ward and unit objectives and changes in treatment programmes and aspects of patient care on the wards. PMID- 6902732 TI - Shared learning for shared care. AB - This is an account of a pilot multidisciplinary course in geriatric care for medical, nursing and physiotherapy students at The Middlesex Hospital, London. The course organization, content and evaluation methods are described. A problem solving approach to shared learning is discussed and the author argues for the development of similar teaching programmes. PMID- 6902733 TI - Commitment by the nurse as the foundation of cancer nursing. AB - To consider commitment by the nurse requires reflection upon what is the unique and particular role and function of nursing in achieving optimum support for patients requiring the help of health care agencies. Excellence in this role and function can only be judged by the quality of care actually delivered to patients. It is useless to boast of excellent teaching programmes, a first class nursing management structure or a flourishing nursing research unit if the standards of nursing practice do not directly reflect the contribution of such agencies. In this paper the author considers the present, apparently subordinate role, of the clinical nurse and suggests that if nurses have a commiotrment to nursing then they must begin to re-establish the position of the clinical nurse as equal to that of her colleagues in other spheres of nursing. Possible ways in which this can be achieved are outlined together with the support that will be required from colleagues in nursing education, management and research. PMID- 6902734 TI - The nurse as health educator: the prevention and early detection of cancer. AB - To assess their potential as health educators 785 female hospital nurses (trained nurses, learners, auxiliaries and nursery nurses) were asked, by means of a postal questionnaire, to give their opinion of three measures of cancer control- the cervical smear test, breast self-examination (BSE) and not smoking. Eighty four % thought the cervical smear test of definite value, 68% had this opinion of BSE, but only 59% thought that it was of definite value not to smoke. Most nurses saw all three measures as having some degree of benefit as few rejected any measure as being of no value. Factors related to whether they regarded a particular measure as being of definite, rather than a lesser degree of value, included (but not necessarily always for all measures) grade, training, age, professional experience of cancer nursing, acceptance of the curability of cancer, knowledge of survival rates, likelihood of reading an article about cancer, and smoking behaviour. It is suggested that nurses' relative assessment of the measures is not based on the intrinsic value of the measures themselves, but on the nurses' personal health behaviour and on the perceived difficulty in undertaking a measure. Furthermore, additional barriers to nurses' likelihood of recommending such measures to others include: lack of understanding of, and skills in health education and an inadequate knowledge base. Thus, simply exhorting nurses to engage in health education is unlikely to succeed. The barriers described have to be taken into account and in particular nurses need to be taught health education skills. PMID- 6902735 TI - Research in gerontological nursing. PMID- 6902736 TI - Physical fitness: its role in health for the elderly. PMID- 6902737 TI - Thank you, Mr. Reed. PMID- 6902738 TI - Problem solving: urinary incontinence in the elderly. PMID- 6902739 TI - A novel approach to the process of life review. PMID- 6902740 TI - Developing a well-elderly assessment clinic: a collaborative approach. PMID- 6902741 TI - Know your community resources: where can you go for nutritional assistance for the elderly? PMID- 6902742 TI - Dissemination of contact activation in plasma by plasma kallikrein. AB - The dissemination of contact activation of plasma was examined by measuring the cleavage of Hageman factor (HF) molecules on two separate sets of kaolin particles, one of which contained all of the components of the contact activation system, HF, prekallikrein (PK) and high molecular weight kininogen (HMWK) in whole normal plasma, and the second set of particles containing only HF and HMWK, being prepared with PK-deficient plasma. After mixing of the particles, cleavage of HF on the second set of particles occurred at a rate similar to that occurring on the first set of particles. This indicated that rapid dissemination and burst of activity of the contact reaction takes place in fluid phase. A supernatant factor, responsibel for the dissemination of the contact reaction, was identified as kallikrein. A rapid appearance of cleaved PK (kallikrein) and HMWK on both the kaolin surface and in the supernate was observed. Within 40 s, > 70-80% of the PK and HMWK in the supernate was cleaved. On the surface, approximately 70% of each radiolabeled protein was cleaved at the earliest measurement. Cleavage of PK by activated HF occurred at least 17 times faster on the surface than in the fluid phase, as virtually no cleavage of PK occurred in fluid phase. Each molecule of surface-bound, activated HF was calculated to cleave at a minimum, 20 molecules of PK per minute. It is concluded that the contact activaton of plasma may be divided into three phases: (a) the reciprocal activation of a few molecules of zymogen HF and PK on the surface, with HMWK acting as cofactor to bring these molecules into apposition; (b) the rapid release of kallikrein into the fluid phase and the continued conversion of PK to kallikrein by each surface-bound molecule of activated HF; and (c) the activation by fluid-phase kallikrein of multiple surface-bound HF molecules, and the cleavage of multiple molecules of MHWK both in fluid phase and on the surface by the soluble kallikrein. The evidence suggests that steps b and c account for a great majority of the generation of contact activation of plasma. PMID- 6902744 TI - Radioimmunoassay of human urinary kallikrein: determination of human urinary kallikrein, II. AB - A radioimmunoassay for the determination of human urinary kallikrein was developed. The sensitivity of the assay was 0.5 microgram/l. Dose-response curves of human submandibular and parotid saliva, sweat, pancreatic juice and bile paralleled the standard curve obtained with purified human urinary kallikrein. Substances with similar antigenic determinants were also found in human serum, ascites, seminal plasma, amniotic fluid, cervical mucus, tears, liquor and faeces, but not in human breast milk and gastric juice. Moreover, immunoreactive material was detected in the urine of guinea pigs, orangoutangs and chimpanzees, but not in the urine of rats, cats and rabbits. Porcine acrosin and kallikrein, as well as bovine trypsin and chymotrypsin, showed no cross reactivity. PMID- 6902743 TI - Detection of active kallikrein in induced blister fluids of hereditary angioedema patients. AB - Six suction-induced blister fluids obtained from five patients with hereditary angioedema (HAE) contained active kallikrein, whereas only two blister fluids obtained from eight normal volunteers contained small amounts of this activity. Kallikrein was present in large amounts of HAE blister fluids as assessed by its ability to liberate smooth-muscle-contracting activity from purified high molecular weight kininogen. It was inhibited by purified antibodies specific for plasma prekallikrein and also by purified C1 inhibitor, but not by antibodies specific for C1s. These observations suggest that activation of the Hageman factor-dependent pathways occurs in the tissues of HAE patients, and once generated, active kallikrein persists in these tissues. PMID- 6902745 TI - Feeding the severely dysphagic patient. PMID- 6902746 TI - Cerebral vasospasm: update and implications. PMID- 6902747 TI - Regaining urinary continence through intermittent catheterization. PMID- 6902748 TI - The concept and application of nursing diagnosis. PMID- 6902750 TI - Understanding sexuality and spinal cord injury. PMID- 6902751 TI - Identifying brain tumors. PMID- 6902749 TI - Stroke: an update on vascular disease. PMID- 6902753 TI - Current concepts of chemotherapy for brain tumors. PMID- 6902752 TI - Identification and treatment of status epilepticus. PMID- 6902754 TI - The dynamic focus of nursing: a challenge to nursing administration. AB - Nursing administrators are challenged to establish a climate that facilitates the use of appropriate frameworks to guide nursing. The author presents an extension of a self-care practice model demonstrating that the focus of nursing strategies changes as the patient's health state changes. Practical application of the proposed model is included. PMID- 6902755 TI - Helping critical care nurses with work-related stress. PMID- 6902756 TI - Computer software. AB - While many nurses are aware that the term "software" denotes the programs of instructions by which the computer operates, most of us could probably benefit by knowing more about software basics--what constitutes a program, what constitutes a system, what distinguishes various types of systems, and levels of computer language, and so forth. Few of us are familiar with the types of computer languages in use today. Fewer still realize that the type of language used to program a system has a significant effect on the resources needed to develop and maintain application programs; that specific languages are best used for specific types of applications; or that the amount of flexibility inherent in a specific system depends largely on the language used to program it. This article attempts to inform nurses at the decision-making level about the characteristics of computer software and their implications as criteria for selecting software systems that perform the required functions as efficiently and economically as possible. PMID- 6902758 TI - Responsible intervention: a legal duty to act. PMID- 6902757 TI - Managing nurse practitioners in ambulatory care: what are the issues? AB - Current emphasis on cost containment of health care services has spurred interest in the expansion of primary care in ambulatory care centers. While nurse practitioners can contribute significantly to ambulatory care, their effectiveness depends on the climate in which they perform--nursing administrators play a key role in creating that climate. This article discusses the issues nursing administrators face in the selection, management, evaluation, and reimbursement of nursing practitioners. PMID- 6902759 TI - The anatomy of peer selection. PMID- 6902760 TI - A clinical advancement program. PMID- 6902762 TI - The numbers game: who shall play? PMID- 6902761 TI - Projecting staffing requirements for intensive care units. PMID- 6902764 TI - Enhancement of paternal--newborn affectional bonds. PMID- 6902763 TI - Interdependence reexamined. PMID- 6902765 TI - Assertive strategies for the nurse-midwife. PMID- 6902766 TI - Planning a nurse-midwifery caseload by a computer simulated model. PMID- 6902767 TI - Jewish religious practices related to childbearing. PMID- 6902768 TI - Nestle boycott. PMID- 6902769 TI - Education exchange: nurse midwives from Yale--what are they doing now? PMID- 6902770 TI - Circulating prostaglandin E2 concentrations and patent ductus arteriosus in fetal and neonatal lambs. AB - We used pregnant sheep and their fetuses as well as newborn lambs (with and without severe respiratory distress due to prematurity) to study the differences in plasma clearance rate, production rate, and circulating concentrations of immunoreactive PGE2. Fetal PGE2 concentrations were significantly higher than simultaneous maternal concentrations. After delivery by cesarean section, all newborn animals were paralyzed and mechanically ventilated. The PGE2 concentrations fell in those lambs that required only minimal ventilatory support (FIO2 < 0.25) and were similar to maternal concentrations by two to three hours. Newborn lambs that developed severe respiratory distress (FIO2 < 0.55) continued to have concentrations that were even greater than fetal concentrations. The elevated PGE2 concentrations in severely distressed lambs were due not only to a decreased plasma clearance rate but also to an increased production rate of PGE2. Since PGE2 appears to maintain the patency of the ductus arteriosus in the fetus and preterm neonate, we examined the patency of the ductus arteriosus in 3-hour old newborn lambs by radioactive microsphere injections. The ductus was more widely patent in lambs with higher concentrations of PGE2. The increased circulating concentrations of PGE2 in newborn lambs with severe respiratory distress may contribute to the pathogenesis of patent ductus arteriosus by exerting an additional vasodilatory effect on the vessel. PMID- 6902771 TI - A conceptual framework for the qualification/validation of ethylene oxide sterilization cycles. PMID- 6902772 TI - Aqueous filter extractables: detection and elution from process filters. PMID- 6902773 TI - 99mTc-radiopharmaceuticals and the Limulus test. PMID- 6902774 TI - An alternate approach for preservative testing of ophthalmic multiple-dose products. PMID- 6902775 TI - Concepts and issues--container/closure microbial validation. PMID- 6902776 TI - Validation of elastomeric closures for parenteral use: an overview. PMID- 6902778 TI - Cesarean patients: delivering the right kind of nursing care. PMID- 6902777 TI - Medicated intrauterine devices: development considerations and clinical uses. PMID- 6902779 TI - Cesarean patients: delivering the right kind of nursing care. The psychological considerations. PMID- 6902780 TI - The myth and reality of cesareans. PMID- 6902782 TI - Aspirin: miracle drug or potential problem? PMID- 6902781 TI - Nursing care of the cesarean patient. PMID- 6902783 TI - Puzzles for patients: a "fun" approach to patient teaching. PMID- 6902784 TI - What one young patient taught her nurses: the privilege of caring. PMID- 6902785 TI - Cerebrovascular disease: tailoring the cure to the cause. PMID- 6902786 TI - Nursing care of the patient with cerebrovascular disease. PMID- 6902787 TI - Discovery of the self in health care. PMID- 6902788 TI - [A thought on the current medical services]. PMID- 6902789 TI - [Continuing education in the 2 year nursing course: the results of a survey on the students' attitudes]. PMID- 6902790 TI - [Keypoints in the 2-year-nursing course, with special reference to educational methodology]. PMID- 6902791 TI - [The current status and future prospect of the 2-year-nursing course]. PMID- 6902793 TI - [Nursing education in a high school nursing course: solution to various problems by facing reality]. PMID- 6902792 TI - [Factors affecting the grades of clinical training: a comparison of the grades of those with clinical experiences as practical nurses and those without]. PMID- 6902794 TI - [Scenes with illness. 8. Tragic past of the leprosy patients]. PMID- 6902795 TI - [Suicide and attempted suicide. I. Facts and statistics]. PMID- 6902796 TI - [Stress ulcer: causes, prevention and therapy]. PMID- 6902797 TI - [Current and required condition of midwives]. PMID- 6902798 TI - Enhanced parotid kallikrein secretion in essential, adrenal, and renoparenchymal hypertension and in advanced renal failure. PMID- 6902800 TI - Moving ahead: building better nursing staffs as a nurse recruiter. PMID- 6902799 TI - Career guide: burnout doesn't have to happen. PMID- 6902801 TI - Medication errors: don't leave medications at the patient's bedside. PMID- 6902802 TI - Sharing: making contact with Juan. PMID- 6902803 TI - Patients shouldn't have to suffer: how to relieve pain with injectable narcotics. PMID- 6902804 TI - Anaphylaxis sudden death anytime. PMID- 6902805 TI - Nursing grand rounds: innovative discharge planning: try it: the results may surprise you. PMID- 6902806 TI - How can you improve care of the hospitalized child? By establishing rapport between parents and staff...and this assessment tool can help you do it. PMID- 6902807 TI - Challenge: Can you help Terry with his sore? PMID- 6902808 TI - Administering oxygen safely: when, why, how. PMID- 6902809 TI - Denial isn't all bad. Sometimes not facing facts is helpful. PMID- 6902810 TI - Monitoring with telemetry. PMID- 6902811 TI - Is part-time nursing the answer for you? Part 1. PMID- 6902812 TI - Caring for the patient in a halo apparatus. PMID- 6902813 TI - When it came to communicating without words... Cyrus was an expert. PMID- 6902814 TI - Consultation: impedance audiometry. PMID- 6902815 TI - Organizational conflict: a creative or destructive force. PMID- 6902816 TI - Influencing an academic future: on planning ahead. PMID- 6902818 TI - Who's who among nursing leaders. PMID- 6902817 TI - Evaluation of the clinical nurse specialist role: development and implementation of a dual purpose framework. PMID- 6902819 TI - Primary nursing and change: a case study. PMID- 6902820 TI - An interview with a rural nurse practitioner. PMID- 6902821 TI - Pediatric hearing loss. PMID- 6902822 TI - Working with families experiencing a cesarean birth. PMID- 6902823 TI - Evolution of holistic practice in nurse practitioners. PMID- 6902824 TI - Management of pediatric poisoning: role of the nurse practitioner. PMID- 6902825 TI - Management of pediatric poisoning: update on first aid management. PMID- 6902826 TI - Management of pediatric poisoning: part I. PMID- 6902827 TI - Management of pediatric poisoning: part II. PMID- 6902828 TI - Pediatric management problems: school phobia. PMID- 6902830 TI - An American PNP in Cuba. PMID- 6902829 TI - Living with juvenile diabetes mellitus. PMID- 6902831 TI - Parenting group for teen-agers fails. PMID- 6902833 TI - Cognitive dissonance: interpreting and implementing faculty practice roles in nursing education. PMID- 6902834 TI - Faculty practice as one component of the faculty role. PMID- 6902832 TI - School phobia: the school anxiety symptom. PMID- 6902836 TI - Evaluating the practice component for faculty rank and tenure. PMID- 6902835 TI - Faculty practice in a nursing center: an integrated model. PMID- 6902838 TI - Promoting collaboration/unification models for nursing education and service. PMID- 6902837 TI - Evaluating the clinical performance of faculty: fact or fantasy? PMID- 6902839 TI - Economic realities of faculty practice. PMID- 6902840 TI - Future perspectives for faculty practice--credibility, visibility, accountability. PMID- 6902842 TI - Raising your political blood pressure. PMID- 6902843 TI - NLN update. PMID- 6902841 TI - Faculty practice: models, methods and madness. PMID- 6902844 TI - The National Health Planning Resources and Development Act of 1974. PMID- 6902846 TI - Piercing the legislative smog. PMID- 6902845 TI - Power-politics-problems. PMID- 6902847 TI - Tax initiatives and their effect on public services. PMID- 6902848 TI - Expert power: the basis for political strength. PMID- 6902849 TI - War on inflation begins with the nurse. PMID- 6902850 TI - Clinical nursing research: beyond the methods books. PMID- 6902852 TI - Negotiating group process experiences. PMID- 6902851 TI - Follow the leader. PMID- 6902854 TI - On writing and writing workshops. PMID- 6902853 TI - If not the 1985 resolution, then what? : an alternative proposal. PMID- 6902855 TI - Teaching the teachers to teach. PMID- 6902856 TI - Women in management: an assessment. PMID- 6902858 TI - Agency staff facilitate student learning. PMID- 6902857 TI - Is the public health nurse's bag anachronism? PMID- 6902860 TI - Knowledge for practice: directions for the future. PMID- 6902859 TI - Nursing research: out of the past and into the future. PMID- 6902862 TI - Summary of 'Knowledge for practice' conference group discussions. PMID- 6902861 TI - Strategies to promote nursing research. PMID- 6902863 TI - Lamaze method of childbirth. AB - The effect of the Lamaze method of childbirth on material adjustment and feelings of crisis experienced by new parents during the postpartum period was investigated utilizing a nonprobability sample of 20 married, primiparous couples. The experimental group consisted of 10 couples who attended Lamaze classes; the control group consisted of 10 couples who did not. The women were in the third trimester of pregnancy at entry into the study. The study was terminated four- to six-weeks postpartum. No significant difference was found in the prebirth marital adjustment scores between experimental and control groups. Although most of the marital adjustment scores of both groups increased after birth, increases were not significant. Postbirth marital adjustment scores were significantly less for the experimental group than for the control group. Experimental group husbands' and wives' prebirth stress scores were significantly greater than those of the control group; stress scores increased significantly after birth for experimental group husbands and control group husbands and wives. Experimental group fathers were under significantly greater levels of postbirth stress than control group fathers, although there was no significant difference in mothers' postbirth stress scores between groups. Most mothers and fathers in both groups experienced slight to moderate feelings of crisis during the postpartum period, but no significant difference was found in crisis scores between groups. PMID- 6902864 TI - Pronominalization: a linguistic facet of the maternal-paternal sensitive period. AB - Two studies of how parents use pronouns in describing their newborn infants are presented. Fathers more often than mothers used the neuter pronoun "it" in describing their new babies. Parents who used the neuter pronoun were more often multiparous, were more likely to have attended childbirth preparation classes, and did not differ from other parents in parenting behaviors or husband-wife communication patterns assessed six months after birth. The data suggest that pronominalization may be a linguistic component of the development of the parental role. PMID- 6902865 TI - Reducing devices for pressure sores with respect to nursing care procedures. AB - In a study that focused on patient comfort and ease of performing nursing care activities 10 common pressure-reducing devices were evaluated for cost, stability, dimensions, positioning, temperature, bounce, noise, cleaning, leakage, weight, mechanical reliability, linen displacement, transfers, bathing, feeding, and dressing. Thirteen subjects--six quadriplegic patients, five paraplegic patients, and two patients with cerebrovascular accidents--and three nurses evaluated each device according to a prearranged schedule of daily patient care activity. Each subject tested five devices at least four times during two separate 24-hour periods. The devices were ranked and rated by subjects and nurses. When Kendall rank correlation coefficients were compared, the tau for ranking by subjects and nurses was .82; for rating, .42; and for ranking and rating combined, .73. Subjective comments by subjects and nurses were examined for relevant factors. PMID- 6902866 TI - Obesity: locus of control, body image, weight loss, and age-at-onset. AB - In a retrospective investigation designed to measure locus of control, body image, and weight loss in Overeaters Anonymous members who had childhood, adolescence, or adulthood onset of obesity, 116 subjects were grouped according to age at onset of obesity and the year they joined OA. A convenience, volunteer sample of OA members completed a demographic data questionnaire, Rotter's Social Reaction. Inventory, and Secord and Jourard's Body Cathexis Scale. Significant overweight percentage differences were not found when the three age-at-onset groups were compared. Significant differences emerged, however, for adolescent onset group persons who were categorized as "old" members; they had a larger weight loss and were more satisfied with their body image. A positive linear relationship between greater perception of internal control and a good body image was found in the entire adulthood-onset group. Weight loss and good body image of the oldest adolescent-onset group probably was the outcome of their association with a self-help group i.e., OA. Assessment of developmental issues related to the time of initial weight gain may indicate which treatment regime would be most effective. PMID- 6902869 TI - Hemodialysis regimen compliance and social environment: a panel analysis. AB - This correlational panel analysis, which investigated compliance behavior of chronic hemodialysis patients, was based on the assumption that attitudes and behaviors are influenced by those of significant others with whom the patient interacts on a continuing basis. Data for the study were collected initially and after a three-year interval, when a panel of 63 patients was identified. Study variables were operationalized by scales relating to social environment and compliance with the hemodialysis regimen. Analysis revealed the existence of statistically significant associations between patients' perceptions of the expectations of significant others, in terms of both primary group members--i.e., family and friends--and secondary group members--i.e., hemodialysis center personnel--and compliance. Multiple regression procedures were used to evaluate these relationships while holding constant the variable of education. PMID- 6902868 TI - Knowledge-informed behavior and the nursing culture: a preliminary study. AB - The pilot study reported in this article was undertaken to identify roles that nurses perform in actual practice and factors and behaviors that enable or prevent them from resolving practice problems in a knowledge-informed way. It was theorized that if nursing roles based on actual practice can be described and if behaviors which enhance knowledge-utilization can be identified, nurses can learn to implement the specific activities needed to ensure the full application of professional knowledge in the practice setting. This preliminary study uncovered six intersecting roles assumed by nurses in the practice of their profession and identified nine categories of behavior and their influence on the ability to use knowledge in carrying out each role. The findings provide additional insight into the nursing culture and suggest the need for changes for education and service. PMID- 6902867 TI - Financial incentive and labor supply of married professional nurses: an economic analysis. AB - The extent to which the supply of nursing services would increase in response to higher nurse compensation and other employment inducements, as the topic pertains to married nurses, was investigated. Higher wages, it was found, probably would not be effective in providing more nursing services but would, indeed, have the opposite effect--of reducing the number of hours worked by registered nurses. PMID- 6902870 TI - Preventive health practices of generic baccalaureate nursing students. PMID- 6902871 TI - Teaching research at the undergraduate level. PMID- 6902872 TI - Research preparation in baccalaureate nursing education. PMID- 6902874 TI - Research Q & A: writing articles. PMID- 6902873 TI - Confidentiality pledge for research grant staff. PMID- 6902875 TI - Organisational and management problems of mental illness hospitals. PMID- 6902876 TI - Quality of life is the challenge - not quantity. PMID- 6902877 TI - To err is human. PMID- 6902878 TI - On location - 3. Powys: sheep country where integration is complete. PMID- 6902880 TI - Ectopic gestation. PMID- 6902879 TI - Nursing care study: a new lease of life. PMID- 6902881 TI - Seclusion: can it be justified? PMID- 6902882 TI - Hospitals ...should do the sick no harm. 9. Respiratory tract infection. PMID- 6902884 TI - Tamsin-- a baby with multiple ileal atresias. PMID- 6902883 TI - Setting up terminal care units. PMID- 6902885 TI - Preparing the infant with a major surgical congenital abnormality for discharge home. PMID- 6902886 TI - 'I didn't know what "SBCU" was...'. PMID- 6902887 TI - Whose life? PMID- 6902888 TI - Recruitment--1. Where are the nurses coming from? PMID- 6902889 TI - Recruitment--1. Assessing the labour market for nurses. PMID- 6902890 TI - Nursing care study. Perthes disease. PMID- 6902891 TI - Aftercare of cardiac surgery patients. PMID- 6902892 TI - These boots are made for walking. PMID- 6902893 TI - Symposium on rehabilitation nursing. PMID- 6902894 TI - Rehabilitation of the patient with a spinal cord injury. AB - The goal of rehabilitation of the person with spinal cord inury is to enable the individual to live successfully in the community. This implies that persons are prepared to care for themselves (or to direct others in their care) and are independent to the greatest extent possible. They are also able to maintain a healthy and adjusted social and vocational life. Independent living centers, providing access to services such as attendant care, have allowed the most severely disabled perons to live indenpendently in the community. PMID- 6902895 TI - Guidelines for rehabilitation of multiple sclerosis patients. PMID- 6902896 TI - Guillain-Barre syndrome: a framework for nursing care. PMID- 6902897 TI - Aphasia and endurance: considerations in the assessment and care of the stroke patient. PMID- 6902898 TI - Alterations in cognitive functioning in the brain-damaged patient. PMID- 6902899 TI - Rehabilitative aspects of neurologic bladder dysfunction. PMID- 6902900 TI - Psychosocial aspects of neurologic disability. PMID- 6902902 TI - Early postpartum nursing care of mother and infant in the home care setting. PMID- 6902903 TI - The cancer patient in the community: a nursing challenge. PMID- 6902904 TI - Health care of the confused elderly at home. PMID- 6902901 TI - Community health nursing in a minority setting. PMID- 6902905 TI - A home care program for patients with rheumatoid arthritis. PMID- 6902906 TI - The hospice movement a unifying force? PMID- 6902907 TI - The function of weeping in the adult. PMID- 6902909 TI - Holistic nursing: the transcendental factor. PMID- 6902908 TI - Academic freedom: a relevant concept for collegiate nursing education. PMID- 6902910 TI - Theory development for a nursing science. PMID- 6902912 TI - A re-examination of the synergistic theory of nursing. PMID- 6902911 TI - The nurse educator and the adult dialysis patient. PMID- 6902913 TI - How well I remember. PMID- 6902914 TI - The psychology of running: implications for nursing and health. PMID- 6902915 TI - Zero base budgeting for nursing services: an opportunity for cost containment? PMID- 6902917 TI - The effect of ordinal position or birth order on child development. PMID- 6902916 TI - The nurse shortage, the president, and the congress. PMID- 6902918 TI - Nursing and the community college movement. PMID- 6902919 TI - The ethics of computer technology in health care. PMID- 6902920 TI - Alcoholism: a disease? an illness? or a sickness? PMID- 6902921 TI - Philosophically speaking. PMID- 6902922 TI - Getting your just deserts. PMID- 6902923 TI - Training the mentally handicapped: the reinforcers. PMID- 6902925 TI - Law and the nurse: the case of the bitten postman. PMID- 6902924 TI - Malnutrition: the spectre at our dining table. PMID- 6902926 TI - Students' forum - ophthalmology. PMID- 6902927 TI - Childhood gastrointestinal allergy: forbidden fruits. PMID- 6902928 TI - Nursing care study. Food allergy: no milk today. PMID- 6902929 TI - A case study in counselling: finding feelings behind the words. PMID- 6902930 TI - A question of balance. PMID- 6902931 TI - Dance away the heartache. PMID- 6902932 TI - Training the mentally handicapped: 'eat your food Simon'. PMID- 6902934 TI - Nurse education: the resource center revisited. PMID- 6902936 TI - Nursing care study--tetanus: a dirty foul... PMID- 6902933 TI - Law and the nurse: who is responsible for health and safety. PMID- 6902935 TI - Clinical--Picture quiz: malaria. PMID- 6902938 TI - Forget the medical diagnosis! PMID- 6902937 TI - Life in the land of plenty... PMID- 6902939 TI - The chicken or the egg? PMID- 6902941 TI - Glan Clwyd Hospital: small is beautiful. PMID- 6902940 TI - Hypertension 1. Too much pressure. PMID- 6902942 TI - Tropical medicine: on the road to Katmandu. PMID- 6902943 TI - Law and the nurse: not so strictly confidential. PMID- 6902944 TI - Microbiology: spreading it around. PMID- 6902945 TI - Nurse education: obedience is not enough. PMID- 6902946 TI - Premenstrual syndrome: defeating the curse of the calendar. PMID- 6902947 TI - Herpes simplex: a cure for some ills. PMID- 6902948 TI - Keeping it in the family. PMID- 6902949 TI - Laetrile: should the dying patient decide? PMID- 6902950 TI - Recognition and management of soft tissue injuries of the ankle in the athlete. AB - The ankle is the site of frequent athletic injuries, the most significant of which include Achilles' rupture, peroneal tendon dislocation, and lateral ligamentous rupture. Evaluation techniques and treatment methods stressing an early but graduated return to function are discussed for the major soft tissue injuries of the ankle. PMID- 6902951 TI - The diagnosis of patellofemoral derangements. AB - An accurate differential diagnosis of a patellofemoral injury can be made through careful observation and history-taking and through the use of x-ray examination. For successful treatment, the physician should be aware that internal derangement of the knee is often caused by a combination of lesions. PMID- 6902952 TI - The treatment of patellofemoral problems. AB - With few exceptions, patellofemoral problems should initially be treated with conservative measures. If results are unsatisfactory and no contraindications are present, surgery should be considered. PMID- 6902953 TI - Injuries of the distal finger. AB - The distal finger is the most commonly injured part of the hand. Adequate initial care should lead to speedy recovery and minimal residual disability. Inadequate initial care or neglect upon the part of the patient can result in a painful and prolonged period of disability. The primary care physician sees and treats the vast majority of these injuries. PMID- 6902954 TI - Injuries of the flexor and extensor tendons. AB - Unless there is vascular compromise, tendon injuries of the hand need not be considered emergencies and can be successfully treated with primary or even delayed primary repair. Methods of treatment for common injuries of the flexor and extensor tendons are discussed. PMID- 6902955 TI - The painful shoulder. AB - Acute peritendinitis calcarea, adhesive capsulitis, and anterior acromion impingement syndrome are common problems of the shoulder. Needle and drug therapy are indicated to relieve pain in the treatment of acute cases, with a regular home program of exercise essential for successful results in all cases. Surgery is recommended only if the nonoperative approach is unsuccessful. PMID- 6902956 TI - Scoliosis. To refer or not to refer. AB - The scoliotic curve, at greatest risk for deterioration during the adolescent growth spurt, can be diagnosed by the simple procedure of the "bend test." Patients with curves less than 20 degrees need not be referred to a specialist, but continuous evaluation of the progression of the curve by the primary physician is essential until skeletal maturity is attained. Braces can control the progression of the curve, although surgical correction may sometimes be indicated. PMID- 6902957 TI - Hip dysplasia in infancy. Diagnosis and treatment. AB - Diagnosis of hip dysplasia in the newborn is entirely by physical examination. In older infants, however, x-ray examination is valuable in confirming the diagnosis. The Pavlik harness is recommended as a safe, simple, and effective method of treatment; but no matter which device is preferred, once hip dysplasia is suspected, treatment should begin immediately. PMID- 6902958 TI - Musculoskeletal problems in hemophilia. AB - Spontaneous deep muscle and joint bleeding is a common characteristic of severe hemophilia, often causing damage to the musculoskeletal system. The development of concentrated replacement factors, however, has made home care programs possible, helped prevent deformity, and improved surgical management. PMID- 6902959 TI - The role of bioengineering in orthopedics. AB - Orthopedic bioengineering is an example of professionals in distinct disciplines applying their skills to problems that require an interdisciplinary approach. Two current research projects, the development of replacement ligaments and tendons and of an absorbable fracture fixation device, illustrate this integrated approach. PMID- 6902960 TI - Junior League Football: risks versus benefits. AB - Major concerns about physical injury, emotional stress, poor adult leadership, and interference with junior high school football programs contribute to the Junior League Football controversy. In the final analysis, benefits of participation in these football programs are shown to far outweigh the risks. PMID- 6902961 TI - Active intestinal transport of methyl red isomers. AB - Transport across the wall of rat jejunum of two isomers of methyl red has been studied. These isomers, meta-methyl red (MMR) and para-methyl red (PMR), are absorbed against a concentration gradient. Uptake consists of three components: rapid adsorption on to the mucosa, a steady uptake proportional to lumen concentration and a reflux which increases exponentially to a limiting value. A substantial part of the uptake is stored in the mucosa, and some of it is metabolized to colourless derivatives. If methyl red is washed out of the lumen after the mucosa has been loaded, there is some reflux into the lumen, but most of the stored methyl red passses into the secretion. The rate of this transport on to the serosal surface is not noticeably diminished until the adverse concentration gradient exceeds 13-14:1. Once the methyl red has been washed out of the lumen there is no further metabolism of methyl red to colourless derivatives. Shifting the lumen pH from 7.4 to 6.4 whilst keeping the tissue fluid pH constant increases the rate of uptake from the lumen by a factor of only 1.68 although the concentration of unionized methyl red is increased approximately 10-fold. It seems that at pH 7.4 about 90% of the uptake is of the ionized form, and that at pH 6.4 this percentage falls to 50. It is concluded that the methyl reds form fresh examples of foreign organic compounds which can be transported actively by the small intestine and that they can be taken up from the lumen into the mucosa in both ionized and unionized states. PMID- 6902962 TI - The effects of bile acids on colonic motility in the rabbit. AB - The content of the rabbit colon has been examined and found to contain the secondary bile acid deoxycholate. Infusions of sodium deoxycholate stimulated colonic motor activity, but the infusion of the primary bile acid sodium glycocholate did not have this effect. Infusions of control amounts of distilled deionized water and isotonic saline were not followed by a significant change in motor activity. Histological damage was caused by 15 mmol.l-1 solutions but was not severe till above 24 mmol.l-1. The possibility that mucosal damage produced motor activity was discounted by the fact that this damage was also present in rabbits treated by sodium glycocholate with no observed motor response. It is postulated that the secondary bile acid, sodium deoxycholate, could have a role in the production of colonic motor activity in the rabbit. PMID- 6902963 TI - Changes in renal haemodynamis and electrolyte excretion after intraventricular infusion of carbachol in conscious sheep. AB - Infusion of carbachol at 10 nmol x min-1 for 30 min into one lateral cerebral ventricle of conscious sheep caused long-lasting increases in arterial blood pressure, heart rate and haematocrit. The increase in haematocrit resulted from release of red blood cells from the spleen. The systemic cardiovascular changes were accompanied by increased glomerular filtration rate (G.F.R.), renal plasma flow (R.P.F) and renal blood flow (R.B.F) which did not return to pre-carbachol levels within 180 min post-carbachol. Intracerebroventricular (ICV) infusion of carbachol increased the rates of sodium excretion and clearance, potassium excretion and clearance, osmolal clearance and solute-free water reabsorption and increased the concentration of vasopressin in arterial plasma. The increase in sodium excretion rate was caused by increased sodium filtration associated with a fall in the proportion of filtered sodium being reabsorbed. The increase in potassium excretion rate resulted mainly from increased potassium secretion possibly stimulated by increased distal sodium delivery and by increased vasopressin levels. The observed effects of ICV carbachol infusion resembled those previously reported for ICV infision of hyperosmotic sodium solutions. PMID- 6902964 TI - Breath hydrogen (H2) and methane (CH4) excretion patterns in normal man and in clinical practice. PMID- 6902965 TI - The depressive action of ammonium chloride on the hepatic blood flow in sheep. AB - Using the 133Xe clearance method it is shown that NH4Cl infusion into the anterior mesenteric vein decreased capillary blood flow in the liver. Phentolamine completely and propranolol partially prevented the depressive action of NH4Cl on hepatic blood flow. NH5Cl infused into the jugular vein provoked a slight increase in the hepatic blood flow. The adrenaline-like action of ammonium ion on the blood circulation in the liver region is discussed. PMID- 6902966 TI - Resting metabolism of inorganic phosphorus and changes during mechanical activation in perfused muscle fibres from Balanus. AB - The levels of inorganic phosphorus (Pi), arginine (and indirectly N-phosphoryl arginine) and adenosine triphosphate (ATP) were measured in intact and perfused muscle fibres from the barnacle Megabalanus psittacus, in resting conditions and during mechanical activity. A twitch caused the liberation of Pi to the intracellular perfusion solution and there was a corresponding decrease in the content of N-phosphoryl arginine of the muscle fibre. Mechanical activation did not induce a significant change in the level of ATP, but since the technique did not allow fast changes in ATP to be observed, the possibility that there was breakdown of ATP followed by a rapid resynthesis cannot be ruled out. PMID- 6902967 TI - Phosphate exchange between high-energy phosphate compounds in resting crustacean muscle. AB - Single giant muscle fibres from Megabalamus psittacus was microinjected with ATP 32P or internally perfused with a solution containing 32P-PArg in an attempt to demonstrate, in the absence of inhibitiors, ATP utilization during mechanical activity with negative results. The rate constant of transfer of 32P from microinjected 32P-PArg to endogenous ATP was studied at two different temperatures, obtaining a Q10 of 1.08 +/- .012. It is concluded that the rate limiting step in the process of transference of phosphate in the resting muscle from balanus is the intracellular diffusion of PArg and not the rate at which the equivalent of Lohman's reaction in invertebrates proceeds. PMID- 6902968 TI - Effects of starvation on cardiovascular function (including the mammary circulation) and water balance in pregnant goats. AB - In conscious goats, starved for 48 hr, in mid-pregnancy (70 days) cardiac output and blood volume decreased; total peripheral resistance increased; heart rate, stroke volume, blood pressure, mammary blood flow and mammary resistance were not significantly affected. In late pregnancy (132 days) cardiac output, heart rate, blood volume and mammary blood flow fell; peripheral resistance increased; stroke volume and blood pressure were not significantly affected. In mid-pregnancy, water consumption fell and the animal entered a stage of negative sensible water balance which persisted for both days of starvation. A similar change was obtained on the first day in late-pregnant goats, but on the second day water consumption increased and positive water balance was restored. Cardiac output, heart rate, blood volume and mammary blood flow was higher in fed late-pregnant than in fed mid-pregnant goats, total peripheral resistance was lower while there were no significant changes in stroke volume or blood pressure. Indications of correlations between litter size and cardiac function were obtained. The results are compared with previous studies on the effects of starvation in lactating animals and are discussed in relation to the control of cardiac function and mammary blood flow in pregnancy and lactation. PMID- 6902969 TI - The role of plasma transferrin in iron absorption in the rat. AB - The question of whether plasma transferrin acts as a carrier of iron from intestinal mucosal cells to the blood plasma was investigated in a series of experiments in the tat. By thoracic duct cannulation and collection of lymph during absorption it was confirmed that nearly all absorbed iron passes directly to portal blood. The total rate of transcapillary exchange of transferrin and the rate of passage of plasma transferrin into the extravascular compartment of the intestinal mucosa were then measured in separate groups of rats. The rate of exchange were insufficient for transferrin to act as the carrier of iron at the rate at which it passes from intestinal cells to portal plasma after ingesting a dose of inorganic iron. Some specific binding of transferrin and cellular uptake of iron by intestinal mucosa was observed after the intravenous injection of transferrin labelled with 59Fe and 125I. It is concluded from these experiments that absorbed iron passes from intestinal cells to portal plasma largely in a low molecular weight form. The passage of plasma transferrin into the interstitial fluid of the intestinal mucosa and binding to mucosal cells probably functions primarily to supply iron to the cells and not to act as a carrier of iron from the cells. PMID- 6902971 TI - Temping for fun and profit. PMID- 6902970 TI - Is it right? Just what do nurses think about the hottest controversies in health care? Here's your answer. PMID- 6902972 TI - Cardiac tamponade when dyspnea spells sudden death. PMID- 6902973 TI - Your best strategy when 'shock lung' strikes. PMID- 6902974 TI - The drug interactions we all overlook. PMID- 6902975 TI - Stool specimens: key to detecting intestinal invaders. PMID- 6902976 TI - Indochina moves to main street: what's behind the 'inscrutable' mask? PMID- 6902977 TI - Match your diagnostic acumen with the experts' in this unique re-creation of an actual case: a patient with multiple pulmonary emboli. What's your diagnosis? PMID- 6902978 TI - Diarrhea: think twice before giving meds. PMID- 6902979 TI - Legally speaking: when your silence is tantamount to fraud. PMID- 6902980 TI - Sound off! Sex in the nursing home? For Lord's sake, why not? PMID- 6902981 TI - Kinetics of the different susceptibilities of the four human immunoglobulin G subclasses to proteolysis by human lysosomal elastase. AB - Human lysosomal elastase cleaves human monoclonal IgG into components that closely resemble the fragments produced by papain digestion. IgG1 produced Fab, Fc and Fab-Fc fragments; cleavage of IgG2 produced F(ab)2, Fab-Fc, Fab and Fc fragments; IgG3 gave rise to almost pure Fab and Fch (Fc covalently joined to the extended hinge region polypeptide of IgG3), and from IgG4, F(ab)2, Fab and Fc fragments were recovered. The relative susceptibilities of the four human IgG subclasses to proteolytic attack by elastase were studied kinetically and showed the following decreasing order of susceptibility: IgG3 > IgG1 > IgG2 > IgG4. The Fab fragment from papain digestion of IgG1 and the corresponding fragment from elastase digestion showed indistinguishable molecular weights and immunochemical identity. PMID- 6902982 TI - [What expectations does the health administration have about the future of health services: the central focus of health activities merely moves slowly]. PMID- 6902983 TI - [Social Research Institute's study of primary health care: report on working conditions of health care nurses]. PMID- 6902984 TI - [General meeting in the Danish Nurses' Unemployment Fund: current political leadership meets at a historic date]. PMID- 6902985 TI - [Research in nursing: the ideal is research worker and nurse in one and the same person]. PMID- 6902987 TI - [Clear declaration on around-the-clock nursing care in the Danish Council of Nursing's congress: nurses contribute in quality around-the-clock care organization]. PMID- 6902986 TI - [Ethical questions in nursing: nursing research of the person as a whole]. PMID- 6902988 TI - [Nursing research: breast feeding is at present well investigated in research]. PMID- 6902989 TI - [Pregnancy leave should be taken under discussion again]. PMID- 6902990 TI - [Danish Nursing Council's 2d vice-president, Benny Andresen, in the annual meeting of representatives: harsh struggle for the defense of professional principles]. PMID- 6902991 TI - [Experts in working environment: give quality high priority in choice of shoes and gloves]. PMID- 6902992 TI - [Drug information: agents for the treatment of cardiac arrhythmias. 1]. PMID- 6902993 TI - [The field of education under discussion in the Danish Nursing Council's congress: the groups of aides we educated are taking over our jobs]. PMID- 6902994 TI - [Discussion on conditions for cooperation with other organizations: nurses don't want to be strapped in front of the party political wagon]. PMID- 6902995 TI - [Subject evenings in the demand for around-the-clock care in Copenhagen: Viborg's experiences cannot be transferred to Copenhagen]. PMID- 6902996 TI - [President of Copenhagen's municipal nursing organization, Esther Klint: nurses should have a seat on official committees]. PMID- 6902998 TI - [Debate on negotiation conditions in the 1980 Danish Nursing Council's congress: we attain most by making our influence felt where we can]. PMID- 6902997 TI - [Social Research Institute's study of home nursing conditions: communities think that widely different personnel groups can replace each other]. PMID- 6902999 TI - [Drug information: agents for the treatment of cardiac arrhythmias. 2]. PMID- 6903000 TI - [Study of requirement characteristics of school health services in 3 schools in the community of Odense: a more case-finding and serviceable school health service]. PMID- 6903002 TI - [After a weeks stay in a French hospital in the middle of a time of economizing: our hospital expenditure is gigantic in proportion to that of the French]. PMID- 6903001 TI - [Nurses from the EEC will not relieve the shortage]. PMID- 6903003 TI - [Reorganization in health service administration]. PMID- 6903004 TI - [Nurse sent out by the Central Popular Association to Lesotho, Africa: hygiene is what one makes of it oneself]. PMID- 6903005 TI - [Clinical instructor course - a link in the preparation of student nurses' education in primary health care: home nurses look ahead to the guidance of student nurses]. PMID- 6903006 TI - [EDP-Committee in the Frederiksborg County Board: advantages and drawbacks of a come-and-go system]. PMID- 6903008 TI - [32 congress members failed to vote for reports on Danish Nursing Council's activities: we cannot share responsibility for what happened in December]. PMID- 6903007 TI - [Research project in the health sector: study of health and working environment]. PMID- 6903009 TI - [From discussions on the Danish Nursing Council's educational activities: multiple proposals and participant numbers]. PMID- 6903010 TI - [If only we would economize now]. PMID- 6903011 TI - [Influence on EDP development requires members' activity]. PMID- 6903013 TI - [Refugee camp Khao I Dang, Thailand: after hunger comes the fear for the future]. PMID- 6903012 TI - [This is what happened at the Danish Nursing Council's congress 1980. Discussions certainly in general agreement on the big issues]. PMID- 6903015 TI - [Pastoral care is also a nursing role]. PMID- 6903014 TI - [Collection of sensitive data]. PMID- 6903016 TI - [Refugee camps in Thailand: refugee camps lie in a zone which can remain combat zone continuously]. PMID- 6903017 TI - [General assembly in the pension fund for nurses: henceforward you will have to contribute more in the share]. PMID- 6903018 TI - [Minister of the Interior: clergy have no need to have access to the patient registry]. PMID- 6903019 TI - [Hospice care - where and how? We can use the elements of hospital nursing care]. PMID- 6903020 TI - [The British hospice system - can we use it? Where prognosis is at hand]. PMID- 6903021 TI - Granulocyte elastase activation and degradation of factor XIII. PMID- 6903022 TI - Enzymatic properties of human Hageman factor fragment with plasma prekallikrein and synthetic substrates. PMID- 6903024 TI - [Breast feeding naturally]. PMID- 6903025 TI - [Breast feeding in an obstetric department]. PMID- 6903023 TI - [From Grafenberg to the Multiload Cu 250--the development of the so-called spiral]. PMID- 6903026 TI - [The nurse's role in breast feeding]. PMID- 6903029 TI - [Sarcoidosis or Besnier-Boeck-Schaumann disease]. PMID- 6903028 TI - [Is nursing a separate independent profession?]. PMID- 6903027 TI - [A new study direction within the HO (higher education)?]. PMID- 6903030 TI - [First Aid in Accidents on high-speed roads]. PMID- 6903032 TI - [A new curriculum for the course of occupational health nurse]. PMID- 6903031 TI - [The future for a healthy growth of nursing sciences]. PMID- 6903033 TI - The clinical pathology laboratory: evaluation of the leukocytes: morphology, production, maturation, and function. PMID- 6903035 TI - How to keep dogs from tearing off bandage wraps. PMID- 6903034 TI - Surgical treatment of venomous snakebite wounds. PMID- 6903036 TI - The atopic dog: success in hyposensitization. PMID- 6903037 TI - Immunologically mediated thrombocytopenia and anemia in a dog. PMID- 6903039 TI - Use of a small animal incubator as an anesthetic chamber for cats. PMID- 6903040 TI - Repair of eyelid lacerations in horses. PMID- 6903038 TI - A thymoma in a cat. PMID- 6903041 TI - Peritoneal fluid. PMID- 6903042 TI - Good cattle-restraining good equipment is essential. PMID- 6903043 TI - Prolapsed rectum and eventration of the small intestine in a pig: surgical treatment. PMID- 6903044 TI - Bovine blocks: paravertebral lumbar anesthesia. PMID- 6903046 TI - Husbandry, nutrition, and diseases of backyard poultry. PMID- 6903045 TI - Evaluation of two cuprimyxin formulations in the treatment of cutaneous and ophthalmic infections in horses and cattle. PMID- 6903047 TI - [Change in the kallikrein-kinin blood system indices in protracted, recurrent and chronic bronchopneumonia in young children]. PMID- 6903048 TI - [State of the kinin system and blood coagulation processes in acute glomerulonephritis in children]. PMID- 6903050 TI - [The yield of the strike]. PMID- 6903049 TI - [The work is a burden and difficult - many quit after a while]. PMID- 6903051 TI - [The poor treatment of nursing personnel must come to an end]. PMID- 6903052 TI - [Home nursing gives the nurse a lot of responsibility]. PMID- 6903053 TI - [The good death]. PMID- 6903054 TI - [Swedish Student Nurses' Association: new education plans must be revised]. PMID- 6903055 TI - [Haganaset - a new hospital entirely built for group care]. PMID- 6903056 TI - [Stockholm's county council indifferent and irresponsible]. PMID- 6903058 TI - [Clinical administrators on strike in Jonkoping: reprisals for employers' foolishness]. PMID- 6903057 TI - [Government proposal on primary health care: agrees with SHSTF's statements]. PMID- 6903059 TI - [We had no alternative but to strike!]. PMID- 6903061 TI - [Final negotiations on wages--these are the results]. PMID- 6903060 TI - [Court case assessment of mistake in examination when air was injected instead of contrast media: both radiographer and roentgen assistant guilty]. PMID- 6903062 TI - [Warning--don't take the wrong bottle]. PMID- 6903063 TI - [Tropical medicine in London]. PMID- 6903064 TI - [Problems are still here but optimism is great]. PMID- 6903065 TI - [18-year-old Melencio manages deliveries and undernourished children]. PMID- 6903066 TI - [New drug dosage forms]. PMID- 6903067 TI - [Summer situation miserable though usual]. PMID- 6903068 TI - [A journey in life]. PMID- 6903069 TI - [Dissenter in management of Professional Teachers' Association: expulsion unreasonably severe punishment]. PMID- 6903070 TI - [Not a single other job is so hard under conflict]. PMID- 6903071 TI - [Negotiation representatives criticize: poor information influence decisions]. PMID- 6903072 TI - [The drug industry should be nationalized]. PMID- 6903074 TI - [Wage negotiations--this is the effect o it on you]. PMID- 6903073 TI - [Conflict in nursing]. PMID- 6903075 TI - [Now the staff gets fixed breaks--by way of increased services]. PMID- 6903076 TI - [every holiday we are anti-social]. PMID- 6903077 TI - ["More of a home atmosphere in the hospital"]. PMID- 6903078 TI - [Professional and organizational issues dominate representative meeting]. PMID- 6903079 TI - [Information, exemptions, interpretations... hot days for county departments]. PMID- 6903081 TI - [Irresponsibility of physicians not planned]. PMID- 6903080 TI - [First days of the strike: physicians try to sidestep the strike]. PMID- 6903083 TI - Does a renal vasodilator system mediate racial differences in essential hypertension? AB - Clinical and epidemiologic data support the contention that black people have a higher incidence and severity of essential hypertension than white people, a phenomenon which is likely due to genetic factors. Physiologic profiles in such patients reveal a striking prevalence of low renin, volume-expanded hypertension, with an exaggerated propensity to sodium retention. A deficiency in the natriuretic, vasodilatory renal kallikrein-kinin system may explain these phenomena and may be of practical importance in the selection of therapy. PMID- 6903082 TI - [A benign form of rheumatoid arthritis, associated with low IgG, IgM and IgA and C3-proactivator concentrations in the serum]. AB - In 31 case studies, 29 patients diagnosed with definite rheumatoid arthritis and 2 patients with probable rheumatoid arthritis were investigated. The duration of the disease averaged 8 years with 3 years being the minimum. These patients received either no basic therapy or had not been treated six months previous to the investigation. Patients with low levels of immunoglobulins were shown to have significantly better functional capacity (Steinbrocker) and significantly less synovitis, erosions and joint destructions despite longer duration of the disease than the control group with higher levels of immunoglobulins and C3-proactivator. All patients with this benign development of rheumatoid arthritis had an IgG level below 1000 mg/100 ml (mean 767 mg/100 ml +/- 166) and low levels of IgA (mean 194 mg/100 ml +/- 73), IgM (mean 111 mg/100 ml +/- 53) and C3-proactivator (mean 23 mg/100 ml +/-6). 50% of these patients had positive rheumatoid factors. PMID- 6903084 TI - The hospitalized rich and famous. PMID- 6903085 TI - Prolapsed mitral valve: living with chest pain. PMID- 6903086 TI - Prolapsed mitral valve syndrome. PMID- 6903088 TI - What it's like to go to convention: a first-time, first-hand report. PMID- 6903087 TI - Digital replantation. PMID- 6903090 TI - An adult's reaction to measles vaccine. PMID- 6903091 TI - Nurse-mother-writer--a dynamic combination. PMID- 6903089 TI - Immunization: what's it all about? PMID- 6903092 TI - Hospice: enabling a patient to die at home. PMID- 6903093 TI - Home as a place to die. PMID- 6903094 TI - Professional action through positive thinking: a case in point. PMID- 6903095 TI - Sensory overload. PMID- 6903096 TI - Conversation with a Navajo nurse. PMID- 6903097 TI - Ethical dilemmas: conflicts among rights, duties, and obligations. PMID- 6903098 TI - Anorexia nervosa: a veiw for the mirror. PMID- 6903099 TI - Anorexia nervosa: an overview. PMID- 6903100 TI - Anorexia nervosa: a behavioral approach. PMID- 6903102 TI - Nursing at the cutting edge of health services reform. PMID- 6903101 TI - Drug therapy in the elderly. PMID- 6903103 TI - Augmentation mammaplasty. PMID- 6903104 TI - Settting up a pnp clinic. PMID- 6903105 TI - Diurnal rhythm of mitosis in rabbit corneal epithelium. AB - Incorporation of 3H-thymidine by rabbit corneal epithelium during the course of a one-hour incubation in vitro varies according to the time of day, suggesting a diurnal rhythm of mitotic activity. Adrenergic decentralization of the cornea does not affect this rhythm. Furthermore, there is no diurnal variation in the basal or sympathomimetically-stimulated cyclic AMP production by freshly excised rabbit corneas, incubated in vitro. Therefore, the diurnal rhythm of corneal epithelial mitotsis in the rabbit is not paced by catecholamines. PMID- 6903106 TI - Cilia in the ciliary epithelium. AB - Cilia in the pigmented and nonpigmented ciliary epithelial cells were studied by electron microscopy in the normal Rhesus monkey eye. In addition cilia formation was studied following paracentesis as well as injection of hemoglobin into the vitreous cavity. In all eyes studied, cilia had a 9 + 0 microtubule pattern; however, some cilia had aberrant arrangement of microtubules. Cilia increased in number and showed elongation in the treated eyes, these newly-formed cilia occasionally extending towards the cell interior opposite to the normal orientation. The results suggested that the formation of ciia can be provoked by a variety of experimental stimuli either with or without drugs. PMID- 6903107 TI - [Histological findings in dysgenesis mesodermalis iridis et corneae Rieger]. AB - The histological examination of an enucleated eye with dysgenesis Rieger showed microcornea, broad anterior synechia, hypoplasia and atrophia of the stroma of the iris as well as of the ciliary body. Excessive proliferations of the endothel combined with the formation of thick glass membranes allow the assumption that the dysgenesis Rieger, the essential progressive atrophy of the iris, the Chandler and Cogan-Reese syndrome are related in their aetiopathogenesis and are only variations of the same proliferative endotheliopathy. PMID- 6903109 TI - Iris fluorescein angiography and Irvine Gass' syndrome. AB - Iris fluorescein angiography and fundus fluorescein angiography were performed three months to three years after cataract extraction in two series of aphakic eyes--32 eyes with vitreous adherence to the wound, and 32 with no vitreous adherence to the wound. In these series there is a significant correlation between dye leakage on iris fluorescein angiography and vitreous adherence to the corneal wound since dye leakage was observed in 40.6% of eyes with vitreous adherence to the wound and only 3.1% of eyes with no vitreous adherence to the corneal wound. On the other hand cystoid macular edema was observed in 100% of eyes with vitreous adherence to the wound associated with dye leakage on iris fluorescein angiography and in only 10% of eyes with vitreous adherence to the wound but no dye leakage on iris fluorescein angiography. PMID- 6903108 TI - Treatment of chronic simple glaucoma with an adrenaline/guanethidine combination at three different dosages (comparative double-blind study). AB - Undesirable side effects have limited the use of adrenaline/guanethidine combinations in the usual concentrations in the treatment of chronic simple glaucoma. Better tolerance to lower concentrations has already been demonstrated in other studies. In the double-blind study described here, three different combinations (adrenaline 1%, 0.5% and 0.2% combined respectively with guanethidine 5%, 3% and 1%) were compared in respect of their depressive action on intraocular pressure and the tolerance shown to them. All three combinations were found to be effective. The combination with the lowest concentration was significantly less hypotensive in its effect than the other two but the number of patients treated was too small to allow a clear distinction to be made between the effects of the other two combinations. Nevertheless, there was a tendency for the effectiveness to fall with decreasing concentration. As far as tolerance was concerned, there was little difference between the middle and lowest concentrations, the latter being that best tolerated. The excellent effect of the strongest concentration was impaired by the poor tolerance shown to it. The comparison between the three combinations was followed by a study of the diurnal pressure changes in patients during the course of the treatment. The slow rise up to midday and the abrupt afternoon fall remain unexplained. The low concentration of the preparation had a better hypotensive action than pilocarpine, while the middle concentration proved even a little better than the beta-blocker Timolol PMID- 6903111 TI - [Metabolic alterations in corneal stroma of rabbit's eye in the early phase after experimental alkali burning (author's transl)]. AB - The cornea and conjunctiva of rabbits are burned with 0.25 n NaOH for exactly 30 s. Then, the cornea and conjunctiva are cleaned with 0.9% NaCl. After sacrification the cornea is rinsed and the levels of the glucose and lactate are measured. The alterations of the metabolites for corneal nutrition are discussed. PMID- 6903112 TI - [Plasmacortisol level in patients suffering from glaucoma]. AB - the plasmacortisol-levels of 27 patients suffering from glaucoma were compared with those of 156 healthy persons. There was no difference between the two groups compared. In addition, a diurnal inversion of the plasmacortisol-level in patients suffering from glaucoma as reported in the literature was not found. PMID- 6903113 TI - Prevention of elastase-induced experimental emphysema by oral administration of a synthetic elastase inhibitor. PMID- 6903110 TI - Retinal anomalies in trisomy 18. AB - The eyes of three patients with trisomy 18, the second most common human autosomal trisomy, were examined histopathologically. In the posterior retina transmission and scanning electron microscopic examinations reveal cytological details characteristic of immature neural retinas. We are able to confirm the report that the posterior retinal pigment epithelium in trisomy 18 has a paucity of mature melanosomes and, in fact, resembles human albino retinal pigment epithelium. The asociation of hypopigmentation and retinal immaturity suggests pigmentation plays a role in the control of the maturation of the neural retina. PMID- 6903114 TI - Ozone inactivation of human alpha 1-proteinase inhibitor. AB - Ozone decreased the trypsin, chymotrypsin, and elastase inhibitory activities of human alpha 1-proteinase inhibitor (alpha 1-PI) both in plasma and in solutions of the pure inhibitor. The total loss of porcine elastase inhibitory activity required 18 mol of ozone/mol of pure alpha 1-PI and approximately 850 mol of ozone/mol of alpha 1-PI in plasma. A corresponding loss of the ability to inhibit human leukocyte elastase was observed. Inactivated alpha 1-PI contains four residues of methionine sulfoxide, in addition to oxidized tyrosine and tryptophan. Electrophoretic analysis demonstrated that the ozone-inactivated alpha 1-PI did not form normal complexes witrh serine proteinases. These findings suggest that the inhalation of ozone could inactivate alpha 1-PI on the airspace side of the lung to create a localized alpha 1-PI deficiency, which might contribute to the development of emphysema. PMID- 6903115 TI - Immunologic identification of elastin-derived peptides in the serums of dogs with experimental emphysema. AB - Pulmonary emphysema is a disease in which peptides formed by the enzymatic degradation of the amorphous component of interstitial elastin may be release from the lung. In order to provide a test that can monitor the destruction of lung elastin invivo, we developed a hemagglutination inhibiton assay that specifically and quantitatively measure elastin-derived peptides in serum. Using this method, was measured the concentration of elastin-derived peptides in the serums of dogs developing emphysema through the administration of porcine pancreatic elastase. Elastin-derived peptides could be detected in the serums for a period of 12 days after the administration of a single 25- or 50-mg dose of elastase, and for at least 40 days after a 100-mg dose. There was a good correlation between the maximal concentration of elastin derived peptides found in the serums and the amount of elastase administered to the animal. This immunologic method may be useful in following the progression of experiment emphysema. PMID- 6903117 TI - More union activity intensifies pressure for tough decisions. PMID- 6903119 TI - Collective bargaining: a nursing dilemma. PMID- 6903118 TI - If wearing a mask, which way should you face for a sneeze? PMID- 6903120 TI - Unions: choice and mandate. PMID- 6903116 TI - In vitro antimicrobial susceptibility of Actinobacillus actinomycetemcomitans. AB - The agar dilution technique was used for determination of the antibiotic susceptibilities of 57 oral isolates and 2 nonoral isolates of Actinobacillus actinomycetemcomitans. Tetracycline, minocycline, and chloramphenicol inhibited more than 96% of the strains tested at a concentration of less than or equal to 2 micrograms/ml; 89% of the strains were inhibited by 2 micrograms of carbenicillin per ml. The other antimicrobial agents tested were less active. Approximately 10% of the A. actinomycetemcomitans strains were resistant to ampicillin, erythromycin, and penicillin G at concentrations of 32 to 64 micrograms/ml. These data suggest that tetracycline and minocycline may be valuable drugs in the treatment of A. actinomycetemcomitans infections. PMID- 6903121 TI - Making a decision on organizing. PMID- 6903122 TI - Unions and continuing education. PMID- 6903123 TI - Is consent valid if patient is confused? PMID- 6903124 TI - Students a natural resource for the OR. PMID- 6903125 TI - Nurses' attitudes toward research. PMID- 6903126 TI - EO exposure poses employee health hazard. PMID- 6903127 TI - Grievances within the nursing profession. PMID- 6903128 TI - A resident's impressions: moonbeams in a nursing home. PMID- 6903129 TI - Q-day at the Mercy Maternity. PMID- 6903130 TI - The result of inadequate documentation in student clinical performance. PMID- 6903131 TI - The education role of the nurse practitioner. PMID- 6903132 TI - Gunshot wounds: initial assessment and management. PMID- 6903133 TI - Mechanism-based inhibitors of elastase. PMID- 6903134 TI - Elastinolytic activity in the rat aortic smooth muscle cells in culture. AB - Elastinolytic activity was examined in cultured rat aortic smooth muscle cells, using Congo Red elastin as a substrate. Elastinolytic activity was demonstrated in the soluble fraction of sonicated smooth muscle cells, with an optimal pH around 10.0. The soluble fraction also showed elastase-like esterolytic activity against the synthetic substrate, N-succinyl-trialanyl-paranitroanilide. PMID- 6903135 TI - Purification and characterisation of an 'elastase-like' enzyme from rabbit polymorphonuclear leucocytes. AB - An enzyme with proteolytic activity has been isolated from the subcellular granules of rabbit polymorphonuclear leucocytes. Purification of the enzyme involved extraction of the granule membranes with 0.01 M sodium phosphate buffer, pH 7.4, containing 1 M NaCl and 0.1% Triton X-100, followed by gel exclusion chromatography on Sephadex G-75. The enzyme hydrolysed p-nitrophenol-N-tert butyloxylcarbonyl-L-alaninate, a synthetic substrate for elastase, but failed to hydrolyse elastin. The enzyme also hydrolysed azo-albumin with a pH optimum between 7.5 and 8.5. Inhibition studies indicated that the enzyme was a serine proteinase (EC 3.4.21.-) and it was found to have an apparent molecular weight of 25 000 by polyacrylamide gel electrophoresis. The purified enzyme behaved as a single on SDS-polyacrylamide gel electrophoresis, had a single isolectric point at pH 5.9, yet showed multiple components on centrifugation. PMID- 6903136 TI - Health hotline makes house calls in Halifax. PMID- 6903137 TI - Care for the caregiver. PMID- 6903138 TI - Stressed? Or burnt out? PMID- 6903140 TI - Six steps to better bonding. PMID- 6903139 TI - Increased intracranial pressure: when assessment counts. PMID- 6903141 TI - New baby in the family. PMID- 6903142 TI - Nursing mothers then and now. PMID- 6903143 TI - Are your students positive about their experience in the clinical area? PMID- 6903144 TI - Adult respiratory distress syndrome. PMID- 6903145 TI - Student nurses and the law. PMID- 6903146 TI - Critical patient behaviors in high blood pressure control. PMID- 6903147 TI - The type A personality: implications for nursing practice. PMID- 6903148 TI - Activation of the alternative complement pathway by extracts of cotton dust. AB - Extracts of cotton dust were tested for their ability to activate the alternative complement pathway in fresh normal human serum (NHS). Alternative pathway activation was determined by a haemolytic assay utilizing glutathione-sensitized human erythrocytes, consumption of alternative pathway components in terms of alternative pathway CH50 units and an immunoelectrophoretic assay to detect split products of activation of factor B. All assays were performed under conditions that have been shown to block the initial steps of classical pathway activation but permit activation of the alternative complement pathway. Results demonstrate that the cotton dust extracts could consume alternative complement pathway proteins in a dose-response manner. The complement activating factor is probably endotoxin since a cotton dust extract obtained by an extraction method for endotoxin yielded the greatest activity. PMID- 6903149 TI - Emergent care of the burn patient. PMID- 6903150 TI - Emergency care of the burn patient. PMID- 6903151 TI - Legionnaires disease. PMID- 6903152 TI - "STAPF" (Staphylococcus aureus). PMID- 6903153 TI - Early management of patients with head injuries. PMID- 6903154 TI - Pacemakers in the emergency department. PMID- 6903155 TI - Cardiopulmonary bypass. PMID- 6903156 TI - Urinary incontinence. PMID- 6903158 TI - [Tularemia]. PMID- 6903159 TI - [Differential diagnosis of fever states in children]. PMID- 6903157 TI - Evidence for di-peptide uptake in Tetrahymena. AB - We have established growth conditions in a synthetic nutrient medium in such a way that utilization of free phenylalanine, but not of phenylalanine-containing di-peptides, limits cell multiplication in species of the genus Tetrahymena (Ciliata). These results suggest that these cells take up intact di-peptides. PMID- 6903161 TI - [Extrauterine pregnancy]. PMID- 6903160 TI - [Diagnosis and management of labor in contracted pelvis]. PMID- 6903162 TI - [Closed injuries of the skull and brain]. PMID- 6903163 TI - [Bronchial asthma attack]. PMID- 6903164 TI - [Health education work among students]. PMID- 6903165 TI - [Prevention of autonomic vascular dystonia in students (material for talks)]. PMID- 6903166 TI - [Importance of health education work among students]. PMID- 6903167 TI - [Work experience of the Municipal Council of Feldshers in Ulan-Ude]. PMID- 6903168 TI - [Development of the professional interests of students]. PMID- 6903169 TI - The effect of kinins (kallikrein) on recovery of motility of frozen human spermatozoa. PMID- 6903170 TI - The politics of health care. PMID- 6903171 TI - Nurse power: a reality now. PMID- 6903172 TI - [Questing and despairing. On the problem of self-destructive behaviour in youths with particular reference to "destructive sects" (author's transl)]. PMID- 6903174 TI - Tune in, turn on, drop out? A look at burnout. PMID- 6903173 TI - [Assessment of brain atrophy by computer tomography (author's transl)]. AB - Computer tomograms from 512 patients with brain atrophy were analysed according to standardized criteria. Exact studies of the outer and inner CSF spaces allowed a redefinition of this disease entity. The limits of change related to the physiological process of aging were established. In addition, an attempt was made to correlate CT findings with EEG tracings and psychiatric criteria. PMID- 6903175 TI - Patients, paychecks and panic--the real world. PMID- 6903176 TI - The nurse in the hospital social system. PMID- 6903177 TI - Belonging to your professional organization: a commitment to personal growth and professional development. PMID- 6903178 TI - Entry into practice: a career entry guide for nurses. PMID- 6903179 TI - Career choice by lifestyle--the better way. PMID- 6903180 TI - In vitro-activity of clavulanic acid and amoxicillin combined against amoxicillin resistant bacteria. AB - The ability of clavulanic acid to inactivate beta-lactamase was investigated using 47 amoxicillin-resistant bacteria. In the presence of 10 mg/l clavulanic acid most strains of staphylococci, Escherichia coli, Klebsiella and Proteus mirabilis became fully amoxicillin-sensitive. This effect of clavulanic acid was in most instances not observed with Serratia marcescens, Proteus inconstans, Pseudomonas aeruginosa, Enterobacter and indole-positive Proteus species. PMID- 6903181 TI - [Orem's conceptual model: a new concept of the profession. I]. PMID- 6903182 TI - [Communicating with the whole human being]. PMID- 6903183 TI - [Decubitus ulcers: prevention is the best treatment]. PMID- 6903185 TI - [Health and culture of the Quebecois]. PMID- 6903184 TI - [Spotlight on the occupational health nurse]. PMID- 6903186 TI - [Nursing assessment and physical examination]. PMID- 6903187 TI - Antibiotic-tolerant mutants of Streptococcus pneumoniae that are not deficient in autolytic activity. AB - Several mutants of Streptococcus pneumoniae were isolated that appeared tolerant, to varying extents, to the lytic and bactericidal effects of some antibiotics that inhibit peptidoglycan synthesis, but were not deficient in autolytic activity. The method used to select the mutants was based on the survival of tolerant mutants during treatment with either bacitracin, benzylpenicillin, D cycloserine plus beta-chloro-D-alanine, or vancomycin. Most (60 to 80%) of the surviving isolates were found to be deficient in autolytic activity, and these were rejected. The smaller proportion that had wild-type sensitivity to deoxycholate-induced lysis was studied further with respect to tolerance to the other antibiotics used in the selection procedures. Two of these mutants (selected by treatment with benzylpenicillin) were tolerant to either benzylpenicillin or D-cycloserine plus beta-chloro-D-alanine, but were supersusceptible, in terms of initiation of lysis, to either bacitracin or vancomycin. The minimal inhibitory concentration values of several antibiotics for these two mutants were identical to those for the wild-type strain. Moreover, the interaction of radioactive benzylpenicillin with the penicillin-binding proteins, examined in whole organisms, also appeared the same as previously found for either wild-type or autolytic-deficient strains of S. pneumoniae. PMID- 6903188 TI - The radioimmunoassay of human urinary kallikrein and comparisons with kallikrein activity measurements. AB - Human urinary kallikrein was purified to homogeneity, and an antiserum to it was raised in rabbits. A RIA was devised which uses this rabbit antiserum (Keq = 2.75 x 10(11) M-1) in a final dilution of 1:2,500,000 and the purified kallikrein labeled with 125I using a lactoperoxidase method. Assay sensitivity is 8 pg kallikrein. Thus far, the assay is specific for human and perhaps monkey urinary kallikrein. Correlations between this assay of immunoreactive kallikrein and the alpha-N-Tosyl-L-arginine-[3H]methylester (Tos-Arg-OMe) activity method or a kininogenase assay were highly significant (r = 0.94 and 0.96, respectively) and show that each assay measures human urinary kallikrein comparably. Low or high dietary sodium intakes, maneuvers known to change human urinary Tos-Arg-OMe esterase excretion, change immunoreactive kallikrein to an equivalent degree. Normal black children, already known to excrete significantly less Tos-Arg-OMe esterase than white children, excrete similarly reduced amounts of immunoreactive kallikrein. Kallikrein excretion in children with cystic fibrosis of the pancreas was not different from that in normal children. The data show that a specific and sensitive direct RIA for human urinary kallikrein has been developed and that both the Tos-Arg-OMe esterase and kininogenase assays measure human urinary kallikrein activity specifically, at least in the described circumstances. PMID- 6903189 TI - Chemotactic activity of elastin-derived peptides. AB - Elastin-derived peptides, produced by digesting human aortic elastin and bovine ligament elastin with human neutrophil elastase, were tested for chemotactic activity. At 100 micrograms protein/ml, elastin digests were nearly as active for monocytes as saturating amounts of complement-derived chemotactic activity. Neutrophils and alveolar macrophages showed less response to elastin peptidces than did monocytes. Fractionation of the digests by gel filtration chromatography disclosed that maximal chemotactic activity eluted in fractions corresponding to 14,000-20,000 mol wt containing most of the desmosine cross-links in the digests. Whole human serum and rabbit anti-elastin immunoglobulin inhibited the chemotactic activity. Purified desmosine also showed chemotactic activity for monocytes, maximal at 10 nM. These findings suggest that elastin-degradation products enriched in cross-linking regions recruit inflammatory cells in vivo and that elastin proteolysis, characteristic of emphysema, may be a signal for recruitment of mononuclear phagocytes into the lungs. PMID- 6903190 TI - Partial properdin deficiency. AB - The action of properdin in supporting complement consumption has been investigated in the serum from two individuals with partial properdin deficiency. Our studies are in agreement with those in which serum were artificially depleted of properdin in showing that serum deficient in properdin results in less C3 consumption in the presence of activators of both the alternative and classical complement pathways. Properdin deficiency did not lessen C3 consumption by C3NeF or CoF, confirming that properdin is not necessary for the action of these substances. Our findings indicate that partial properdin deficiency is innocuous but that complete absence of properdin may severely limit one's ability amplify complement activation. PMID- 6903191 TI - Immunological studies of prekallikrein, kallikrein, and high-molecular-weight kininogen in normal and deficient plasmas and in normal plasma after cold dependent activation. PMID- 6903194 TI - Jerry: a difficult - but not impossible - patient. PMID- 6903192 TI - Relation of putative thioester bond in C3 to activation of the alternative pathway and the binding of C3b to biological targets of complement. AB - The reaction of [14C]methylamine with native human C3 led to the stoichiometric incorporation of methylamine, loss of hemolytic activity, and the concomitant exposure of a sulfhydryl group that could be labeled with [14C]iodoacetamide. Both labeled sites were located in the C3d portion of the alpha-chain, which is known to contain the metastable binding of C3b. The methylamine-modified C3 [C3(CH3NH2)] was shown to exhibit many of the functional properties of C3b, although the C3a portion of the molecule remained covalently attached. C3(CH3NH2) bound Factor B and beta 1H, and could be cleaved by C3b inactivator in the presence of beta 1H. C3(CH3NH2) added to human serum caused activation of the alternative pathway and consumption of C3. In presence of Factors B and D and Mg++, C3(CH2NH2) formed a C3 convertase. The convertase-forming material could be removed from solution by anti-C3a Sepharose and the preformed convertase was completely inhibited by purified antibody to C3a. This antibody did not affect the function of the C3 convertase that contained C3b. Similar functional properties were exhibited by C3 exposed for short periods of time to relatively low concentrations of chaotropic reagents, such as KSCN or guanidine. These results suggest that the initial C3 convertase of the alternative pathway may be formed from native C3, without proteolysis, by the attack of a variety of nucleophiles including water. The C3 convertase formed from this altered C3 then generates by proteolytic cleavage the initial metastable C3b that is capable of attaching to receptive surfaces. Conversion of C3 to C3b exposes one sulfhydryl residue as does modification of C3 with methylamine. When the C3d portion of C3b bound to zymosan particles via the metastable binding site was treated with radiolabeled methylamine, the fragment was released from the particles in radiolabeled form. These findings are consistent with the concept that native C3 contains an active carbonyl group, probably in the form of a thioester, which can either react with water to form functionally C3b-l;ike C3 or, upon enzymatic conversion of C3 to C3b, allows C3b to form an ester bond with hydroxyl groups on the target surface. PMID- 6903193 TI - Fetal lamb lung phosphatidylcholine: response to asphyxia and recovery. AB - Acute fetal asphyxia resulting from maternal blood loss and hypotension causes a reduction in the incorporation of precursors into disaturated phosphatidylcholine, the principal lipid in the pulmonary surfactant. Treatment of the maternal hypotension is associated with return of fetal lung DSPC synthesis to control levels by 72 hours. PMID- 6903195 TI - Myasthenia gravis: the mysterious masquerader. PMID- 6903197 TI - You have a role - and a responsibility - in the anti-smoking campaign. PMID- 6903196 TI - The struggle to the top of the mountain. PMID- 6903198 TI - Challenges in nursing. PMID- 6903200 TI - [Early therapy and management of spinal cord injuries]. PMID- 6903199 TI - [The current status of spinal cord injuries--etiology and types of injuries]. PMID- 6903201 TI - [Implication of "acceptance" of injuries by spinal cord injured patients and their psychological support]. PMID- 6903202 TI - [Rehabilitation of spinal cord injuries and current rehabilitation problems]. PMID- 6903203 TI - [Management of decubitus ulcer in patients with spinal cord injuries]. PMID- 6903204 TI - [Care involved in urination in spinal cord-injured patients--prevention of infection and problems involved in their care]. PMID- 6903205 TI - [Education of patients with spinal cord injuries at the time of discharge from our hospital and observation of the results]. PMID- 6903206 TI - [Assistance of a patient with a cervical cord injury resisting the ADL training]. PMID- 6903207 TI - [Home nursing of patients with spinal cord injuries--a case study]. PMID- 6903208 TI - [Care of the urinary tract of patients with spinal cord injuries. A conference]. PMID- 6903209 TI - [The etiological mechanism of diarrhea]. PMID- 6903210 TI - [Physiology and mechanism of defecation]. PMID- 6903211 TI - [Nursing of a child with persistent diarrhea]. PMID- 6903212 TI - [Training of defecation control in a child with affective disturbances]. PMID- 6903213 TI - [Teaching patients to rotate injection sites]. PMID- 6903214 TI - [Case reports on tetanus--nursing planning during the acute stage]. PMID- 6903215 TI - [Re-evaluating the care for maternal milk--an observation using bacteriological data]. PMID- 6903216 TI - [Ecology of the operating room (1)--a survey on airborne bacteria]. PMID- 6903217 TI - [Ecology of the operating room (2)--contamination of the floor]. PMID- 6903218 TI - [Anatomy and physiology of heart diseases]. PMID- 6903219 TI - [Spinal cord injuries]. PMID- 6903220 TI - Economic & general welfare report: the collective bargaining process. PMID- 6903222 TI - Poverty in paradise: inside the Dominican Republic. Interview by Kathy Busch. PMID- 6903221 TI - Ethics: models of nurse/patient physician relations. PMID- 6903223 TI - [Plasma esterase activity in acute myocardial infarct]. PMID- 6903224 TI - [Change in the state of the renal kallikrein-kinin system in hypertension]. AB - The work discusses the results of the investigation of kallikrein excretion in the urine in healthy individuals and in patients with hypertensive disease examined under similar conditions. The following tests were undertaken: tests for tolerance to physical exercise (walking and exercise on the bicycle ergometer) and to emotional stress and test with decreased extracellular fluid volume and sodium content (acute and long-term furosemid administration) or with their increase (intravenous salt infusion). Functional reorganization of the renal kallikrein-kinin system was revealed in patients with hypertensive disease. It was expressed in an increase in the activity of this humoral system in patients with the initial stage of the disease when they were examined in a state of physical rest and its decrease in all stages of the disease when examined during physical activity. A reduction was noted in the reaction of the kallikrein-kinin system of the kidneys to stimulation associated with acute or long-term (stage IIB) decrease in volume. A simultaneous increase in kallikrein excretion in the urine in response to acute and long-term salt tolerance tests was noted in hypertensive disease. PMID- 6903225 TI - The who, what, when, why and how of professional negotiations for nurses. PMID- 6903226 TI - Preliminary report. Gamma camera detection of oleic acid alveolar-capillary albumin leak. PMID- 6903227 TI - Prolonged rupture of the membranes during pregnancy: case history. PMID- 6903228 TI - Mandatory continuing education for continued registration. PMID- 6903229 TI - Text of a press statement by the Federal Minister for Education re government decision on nurse education and training (Sax Report). PMID- 6903230 TI - Treatment and staff attitudes--an addendum to 'psychiatric hospitals, treatment of schizophrenia and staff attitudes'. PMID- 6903232 TI - 'The good old days.'. PMID- 6903231 TI - Special problems of suicidal adolescents. PMID- 6903233 TI - Determining the quality of nursing care. PMID- 6903235 TI - [Croupous pneumonia]. PMID- 6903236 TI - [Complications of acute pneumonias]. PMID- 6903237 TI - [Chronic pneumonia]. PMID- 6903238 TI - [Therapeutic physical exercise in croupous pneumonia]. PMID- 6903239 TI - [Respiratory tract secretion examined for the microflora]. PMID- 6903240 TI - [Role of the nurse in treating burn patients]. PMID- 6903241 TI - [Use of koumiss made from cow's milk in liver diseases]. PMID- 6903242 TI - [Acute focal pneumonias]. PMID- 6903243 TI - [First aid in syncope, collapse and shock]. PMID- 6903244 TI - [Erythrocyte sedimentation rate]. PMID- 6903246 TI - [Work of the nurse in the inhalation room]. PMID- 6903245 TI - [Venipuncture]. PMID- 6903247 TI - [Technic of performing intrarectal oxygen therapy]. PMID- 6903248 TI - [Rendering first aid in acute oxygen deficiency due to drowning]. PMID- 6903249 TI - [Work organization for the head hospital nurse]. PMID- 6903250 TI - [Health bulletin]. PMID- 6903251 TI - [Combined drug therapy of arterial circulation disorders]. PMID- 6903252 TI - [Kallikrein and electrolyte excretion in essential hypertension]. PMID- 6903253 TI - Smoking and health. PMID- 6903254 TI - Handicap and brain haemorrhage in the neonate. PMID- 6903255 TI - Passive smoking--the evidence confirmed. PMID- 6903256 TI - The health problems of retirement areas. PMID- 6903258 TI - Atlanta--my American connection. PMID- 6903257 TI - Return of the sheath. PMID- 6903259 TI - The use and care of cystoscopes. PMID- 6903260 TI - The development of the modern endoscope. PMID- 6903261 TI - Increased kallikrein excretion in spontaneously hypertensive rats and its inhibition by 6-hydroxydopamine. AB - Urinary kallikrein excretion was studied in young, stroke-prone, spontaneously hypertensive rats (spSHR). Seven-week-old spSHR were found to excrete more kallikrein into the urine than normotensive Wistar Kyoto control rats (WKR). "Chemical sympathectomy", induced by 6-hydroxydopamine (6-OHDA) immediately after birth, resulted in normotensive blood-pressure levels and in a reduction of kallikrein in spSHR. In normotensive WKR, blood pressure and urinary kallikrein excretion were only slightly diminished by 6-OHDA. The results suggest a relationship between sympathetic activity and kallikrein excretion, being especially pronounced in spSHR, which have an elevated sympathetic activity. PMID- 6903262 TI - U.S. health care: reasons for increased costs. PMID- 6903263 TI - Should the battle go on? PMID- 6903264 TI - Notes on gerontological nursing. PMID- 6903265 TI - Who's professional? PMID- 6903267 TI - Nurses as health planners. PMID- 6903266 TI - Using video tapes to teach therapeutic interaction. PMID- 6903268 TI - The continuing nurse learner: who and why. PMID- 6903269 TI - An associate degree educator supports the entry to practice resolution. PMID- 6903270 TI - Criteria for evaluating nursing process models. PMID- 6903271 TI - NOrmal and abnormal micturition. PMID- 6903272 TI - Treatment of chronic renal failure. PMID- 6903273 TI - Urinary tract investigations. PMID- 6903274 TI - Careers in nursing. Renal nursing. PMID- 6903275 TI - Urinary diversion. PMID- 6903276 TI - Pictures in nursing: incontinence aids. PMID- 6903277 TI - What can urinalysis tell you about your patient? PMID- 6903278 TI - Urinalysis. PMID- 6903279 TI - Stress incontinence. PMID- 6903280 TI - Assessing incontinence. PMID- 6903281 TI - Urethral catheterization. PMID- 6903282 TI - Toilet training the mentally handicapped. PMID- 6903283 TI - A study of 15 incontinent women. PMID- 6903284 TI - Questions mothers ask about toilet training. PMID- 6903285 TI - Incontinence in the elderly. PMID- 6903286 TI - The health professions in Europe. 3. Can we control our destiny? PMID- 6903287 TI - A girl called Jo. PMID- 6903288 TI - Legal notes: vicarious liability. PMID- 6903289 TI - Reorganisation--the government's blueprint. PMID- 6903290 TI - Continuing education: American attitudes. PMID- 6903291 TI - The baccalaureate--an attainable goal. PMID- 6903292 TI - Metal fume fever- a case review. PMID- 6903293 TI - Some aspects of consultation and management by objectives. PMID- 6903294 TI - Union-busting - it's big business. PMID- 6903295 TI - Nursing: a potential political force. PMID- 6903296 TI - IRB's: can they serve your clients and staff? PMID- 6903297 TI - Educational preparation for nursing--1979. PMID- 6903298 TI - Supply and demand for registered nurses: some observations on the current picture and prospects to 1985. Part 1. PMID- 6903300 TI - National trends affecting credentialing. PMID- 6903299 TI - Credentialing in nursing--design for a workshop. PMID- 6903301 TI - Critique of the credentialing study and identification of issues. PMID- 6903302 TI - Strategies for change. PMID- 6903303 TI - Together we can shape nursing's future. PMID- 6903305 TI - Systems of life no 69: systems and signs: the cardiovascular system-4. PMID- 6903304 TI - The League's participation in the credentialing study. PMID- 6903306 TI - Communication and the nurse. PMID- 6903307 TI - Stress, smoking and nursing. PMID- 6903308 TI - Extending the register. PMID- 6903310 TI - A conduit for life. PMID- 6903309 TI - Raze out the written troubles of the brain. PMID- 6903312 TI - 'The professionals provide practical care and sympathy; ileostomy association visitors provide empathy.' here we look at their work and how they are trained for it. All in the same boat. PMID- 6903311 TI - Care of the ostomist undergoing radiotherapy and anti-tumour chemotherapy. PMID- 6903313 TI - Sickle cell disease. An inherited disorder for which as yet there is no specific treatment without causing unacceptable toxicity. PMID- 6903314 TI - Instant replay. PMID- 6903315 TI - If there's one thing that definitely doesn't make for successful community psychiatric nursing, it's ... complacency! PMID- 6903317 TI - A rethink on nurse education. PMID- 6903316 TI - X-ray anatomy 5. PMID- 6903318 TI - Taking the lid off... sexuality and the nurse. PMID- 6903319 TI - A little discomfort for a worthwhile cause. PMID- 6903320 TI - The travelling scholars. PMID- 6903321 TI - Nursing care study: triple coronary vein--grafts. PMID- 6903323 TI - Educating the educators. The new Diploma in Nursing of the University of London. PMID- 6903322 TI - Recruitment--2. Recruitment of trainee nurses--the role of schools of nursing. PMID- 6903324 TI - A new approach to qualification as a teacher of nursing. PMID- 6903325 TI - An alternative view. PMID- 6903326 TI - Learner centred education. PMID- 6903328 TI - Why this condescending attitude? PMID- 6903327 TI - Challenge of paediatric nursing. PMID- 6903329 TI - Nurses of India, unite. PMID- 6903330 TI - World Health Day, 1980: smoking or health, the choice is yours. PMID- 6903331 TI - The smoker - a family menace. PMID- 6903332 TI - Nine steps to prevent smoking. PMID- 6903333 TI - Nurses and ethical issues. PMID- 6903335 TI - Outline of primary health care. PMID- 6903334 TI - Research Orientations in nursing--XV. my two sets of scores seem related how can I analyze these relationships? PMID- 6903336 TI - Multi-purpose worker scheme: nurses' place in the health care system. PMID- 6903337 TI - Research orientations in nursing--XVI. I have stated my hypotheses now what do I do with them--Part I. PMID- 6903338 TI - The health team: the nursing component. PMID- 6903339 TI - An ash tray for your lung. PMID- 6903340 TI - Research orientations in nursing--XVI. I have stated my hypotheses now what do I do with them--Part II. PMID- 6903341 TI - Abortion practices in the rural areas around Najafgarh. PMID- 6903342 TI - Country health programming: a tried out managerial tool. PMID- 6903343 TI - Bedside manners: your biggest gift. PMID- 6903344 TI - Meaning of discipline: the day you set your own rules. PMID- 6903345 TI - Opportunities that go by: point of view concerning World Conference for Women 1980. Interview by Tina Jorgensen. PMID- 6903346 TI - Status of nursing. PMID- 6903348 TI - The changing roles of the Indian nurses. PMID- 6903347 TI - Research orientations in nursing--XVII. My chi-square is significant. Is that analysis or interpretation. PMID- 6903349 TI - Reflections on our needs of motivational factors and attitudes which are significant in recruiting students for basic diploma nursing in India. PMID- 6903350 TI - Attitudes to nursing in India. PMID- 6903351 TI - Need for rural-oriented research in health field. PMID- 6903352 TI - Nursing today and tomorrow. PMID- 6903354 TI - Why nurses form unions. PMID- 6903353 TI - Research orientations in nursing--XVIII. Is my hypothesis statistically significant--Part I. PMID- 6903355 TI - When patients are prisoners they lose their right to refuse life-maintaining treatments. PMID- 6903356 TI - Reporting incompetent colleagues. PMID- 6903357 TI - Nurse anesthetists: written contracts. PMID- 6903358 TI - Legal lesson of the month. Force-medicating the mental patient: assault? Case in point: Goedecke v. State (602P. 2d 123-COLO.). PMID- 6903359 TI - Legal case briefs for nurses. Minn.: tylenol/codeine PRN: orders; LA.: retarded patients and accidents. PMID- 6903360 TI - Treatment accidents: government nurses. Case in point: Gregory v. Martyak, Kapish et als (404 A. 2d 188-PA.). PMID- 6903361 TI - Charting: importance of nurses notes. PMID- 6903362 TI - Medication mistakes: fire the nurse? Case in point: Edgewood Nursing Center v NLRB (581 F. 2d 373 - PA.). PMID- 6903363 TI - Legal case briefs for nurses. LA.: hepatitis: were the needles sterile? PMID- 6903364 TI - Legal case briefs for nurses. N.Y.: weapon, marijuana: R.N. license suspended. PMID- 6903366 TI - Charting: nursing care data sheets. PMID- 6903365 TI - Nursing assessment and nursing judgment. Case in point: Lindsey v. Clinic for Women (253 S.E. 2d 034 - N.C.). PMID- 6903367 TI - Legal lesson of the month. Hospital employees: religious rights. Case in point: State v. Genesee Hospital (418 N.Y.S. 2d 687 - N.Y.). PMID- 6903368 TI - Legal case briefs for nurses. III.: Nurses failed to call M.D. Colo.: Pronouncing death; brain death. PMID- 6903369 TI - Clinical nursing. Tracheotomy: post-operative nursing care. Case in point: Higgenbotham v. Ochsner Foundation Hosp. (607 F. 2d 653 - LA.). PMID- 6903370 TI - Special duty nursing: who pays the nurses? PMID- 6903371 TI - Drug abuse by RN's: unprofessional conduct? Case in point: Leib v. Conn. Bd. of Examiners for Nursing (411A.2d42-CONN.). PMID- 6903372 TI - Legal case briefs for nurses. D.C.: Hysterectomy complications; no liability. PMID- 6903373 TI - Legal case briefs for nurses. N.Y.: Breast resection: no informed consent. PMID- 6903375 TI - Nursing assessments: legal impact. PMID- 6903374 TI - Suicide in Air Force Hosp.--R.N. liability? Case in point: Abille v. United States (482 F. Supp. 703--CALIF.). PMID- 6903376 TI - Blue Cross and private nursing service. Case in point: Heiser v. Blue Cross of Ohio (401 N.E. 2d 483--OH). PMID- 6903377 TI - S.C.: RN-MD communication mixup. PMID- 6903378 TI - TX: unregistered grad: equipment error. PMID- 6903379 TI - Public health nursing: child custody proceedings. Case in point: in re Hoppe (289 N.W. 2d 613-IA). PMID- 6903380 TI - Nurse practitioners and professional neglicence. PMID- 6903381 TI - Nurses unlawfully fired. Court: rehire! Case in point: Misericordia Hosp. Med Ctr. v.N.L.R.B. (89 LC P. 12, 098, 6/6/80). PMID- 6903382 TI - Legal case briefs for nurses. CA.: hospital liability for R.N. felony. LA.: foley catheter error: liability. PMID- 6903383 TI - Doctor's orders and nurse's judgment. PMID- 6903384 TI - Psychiatric assessment--R.N.'s vs. psychologists. Case in point: Delicata v. Bourlesses (404 N.E. 2d 667--Mass.). PMID- 6903385 TI - Legal case briefs for nurses. IL: R.N.'s delayed medication: fatality; N.Y.: kidney disease: orders ignored. PMID- 6903386 TI - Nursing assessment: recognize ruptured appendix? Case in point: Vassey V. Burch (262 S.E. 2d 865--N.C.). PMID- 6903387 TI - [Sensitivity to combined metronidazole and penicillin in 227 strains of non sporulated anaerobic bacteria]. AB - Combined metronidazol-penicillin, used in large amounts corresponding to the selective concentrations in vitro of 25 + 25 IU, may be assumed to be effective in all clinical infections in which one or several anaerobes are implicated. The experiments carried out demonstrate that this is valid for all categories of Grampositive or Gramnegative non-sporulate anaerobes. The antibiotic concentrations used are well tolerated by the human organism. PMID- 6903388 TI - Sex Q and A. Frank answers to your most delicate patient-counseling questions. PMID- 6903389 TI - Chest tubes. The crucial points you mustn't forget. PMID- 6903390 TI - Puzzle out the cause of this patient's double trouble. PMID- 6903391 TI - Would you have drawn this 'drunken driver's blood? PMID- 6903392 TI - The drug interactions we all overlook. PMID- 6903393 TI - Indochina moves to Main Street. The refugees and childbearing: what to expect. PMID- 6903394 TI - Respiratory tract cultures. When identifying the pathogen is crucial to the cure. PMID- 6903395 TI - The shortage. How it's changing nursing. What you can expect. PMID- 6903397 TI - Sound off! Are you letting your aides go to waste? PMID- 6903396 TI - Legally speaking: her return to nursing became a disaster. PMID- 6903398 TI - What is nursing? PMID- 6903399 TI - Nursing values need scrutiny. PMID- 6903400 TI - Continuing education: voluntary and mandatory? PMID- 6903402 TI - Nursing shortage: an issue of quality. PMID- 6903401 TI - [Pneumococcal pneumonia: epidemiology, therapy, immunoprophylaxis]. AB - Despite modern antibiotic therapies, pneumococcal pneumonia still remains a serious epidemiologic problem. Some 25% of pneumococcal pneumonias are accompanied by bacteremia. The mortality rate in these forms is some 17%, and in patients above 50 it is as high as 28%. Early toxic injury is responsible for the high mortality rate, which is as high as 13,000-60,000 deaths every year in the USA. Several resistant strains of pneumococci have recently been discovered, and for all these reasons research into active immunization against pneumococci has been resumed. A vaccine is now available which consists of polysaccharide antigens of the 14 most important serotypes and confers a protection rate of some 80% against pneumococcal pneumonia. Vaccination is recommended for elderly and debilitated persons in particular. PMID- 6903403 TI - Nurses run hurricane shelters. PMID- 6903404 TI - Know your generics: the thiazide drugs. PMID- 6903405 TI - Hospice: a gift of love. PMID- 6903406 TI - Report of the task force to study structural alternatives. PMID- 6903407 TI - The Good Samaritan in Virginia. PMID- 6903408 TI - Fifteen cent stamp stops million dollar business. PMID- 6903409 TI - Accepting death. Interview by Juliana van Olphen Fehr. PMID- 6903410 TI - Guidelines for collaboration of pharmacists and nurses in institutional care settings developed by American Nurses' Association and American Society of Hospital Pharmacists. PMID- 6903411 TI - Emotional first aid. PMID- 6903412 TI - Acute aortic dissection. PMID- 6903413 TI - Learning on your own for credit. PMID- 6903414 TI - Project Health PACT in action. PMID- 6903415 TI - Home peritoneal dialysis. PMID- 6903416 TI - Southeast Asian refugees: life in a camp. PMID- 6903417 TI - Southest Asian refugees: life in America. PMID- 6903418 TI - Southeast Asian refugees: from Khao I Dang to life in America. Health screening in a family clinic. PMID- 6903419 TI - The nurse as advocate. PMID- 6903420 TI - How children, mothers, and nurses view primary and team nursing. PMID- 6903421 TI - When hope dies--so might the patient. PMID- 6903422 TI - Amyotrophic lateral sclerosis. PMID- 6903423 TI - Care plans in long-term facilities. PMID- 6903424 TI - Health teaching for recovering alcoholic patients. PMID- 6903425 TI - Unit dose. PMID- 6903426 TI - When parents disagree on treatment. PMID- 6903427 TI - Effect of vasopressin on renal kallikrein excretion. AB - In an attempt to investigate a possible interaction between vasopressin and the renal kallikrein-kinin system, renal function and urinary kallikrein excretion were monitored in trained conscious dogs and in anesthetized rats in water diuresis and in vasopressin-induced antidiuresis. Vasopressin elevated urinary kallikrein excretion in a dose-dependent way in both species, with concomitant increases in urinary osmolality and electrolyte excretion. A significant increase in kallikrein excretion was observed with a dose of vasopressin as low as 2 mU . kg-1 . h-1 in the dog and 3 mU . kg-1 . h-1 in the rat without a change in renal hemodynamics. In the rat vasopressin-induced changes in kallikrein excretion were positively correlated with changes in sodium and potassium excretion and negatively correlated with changes in free water clearance. It is concluded that vasopressin over its normal physiological range of concentration stimulates renal kallikrein secretion. PMID- 6903428 TI - Information coding in the visual system: a new hypothesis. AB - Experiments on subjective color sensations using a special signal generator and a standard TV monitor (black and white) led to a new hypothesis on information coding in the visual system. According to this hypothesis a trigger signal is required which restores the phase correlation of the pulse-coded spiking of the neurons transmitting visual information from the eye to the brain. The "shift effect" ("periphery effect"), either artificially induced or initiated by microsaccades, might act as the postulated trigger. PMID- 6903429 TI - Shigella endotoxin-induced ocular inflammation in the normal and sensory denervated rabbit eye. AB - Injection of Shigella endotoxin (2 mug) into the vitreous chamber of a normal rabbit eye induces on infiltration of polymorphonuclear leucocytes, miosis, a moderately intense dilation of iris, conjunctival and limbal vessels, and a breakdown in the blood-aqueous and blood-vitreal barriers. Significant amounts of soluble blood protein and prostaglandin-like (PG) material are found in the aqueous and vitreous humours withdrawn at 24 h. Endotoxin injected into the sensory denervated eye elicits similar vascular changes which appear to occur less rapidly than in normal eyes. conversely, the levels of aqueous and vireal PG like material, as well as the capacity of excised irides to form PG from exogenous precursors, seems greater in the denervated eyes. If PG is an important mediator of ocular changes in the early phases, the results suggest that the action of this inflammatory autacoid in facilitating the ocular changes is less effective in eyes deprived of functional sensory nerves. PMID- 6903430 TI - Macula and periphery: their contributions to the visual evoked potentials (VEP) in humans. AB - An alternating checkerboard pattern subtending a visual angle of 25 min arc is capable of eliciting remarkably high amplitudes of visually evoked potentials (VEP) outside a visual angle of 2.5 degree. These contributions cannot be neglected when evaluating a VEP response obtained with a larger field of stimulation. When the retina is consecutively stimulated by concentric frame shaped stimuli, the algebraic sum of all single cortical responses augmented the cortical response obtained when stimulating the whole field simultaneously by approximately 30%. This finding may be explained by the inhibiting interactions within the receptive field organisation of the retina. PMID- 6903431 TI - Peripheral retinal degenerations and breaks. AB - One-hundred-three patients referred for evaluation of peripheral retinal lesions were reviewed; 56 eyes had peripheral degenerations without breaks, 62 eyes had atrophic holes, and 88 eyes presented retinal tears. Peripheral degenerations of the snail-track and typical lattice-like types occurred with reasonable uniformity throughout the periphery and were seen symmetrically in both eyes. Atrophic retinal holes frequently occurred within these degenerative areas. Peripheral degeneration with or without holes were ofter seen in young myopes and occurred mostly without giving rise to symptoms. Retinal tears occurred in older, predominantly hyperopic or emmetropic subjects, and usually presented with symptoms of acute entopsiae and/or photopsiae. The tears presented mainly in the upper temporal quadrants and were only associated with lattice degenerations of the ipsi or contralateral eye in one-third of cases. It was concluded that the population suffering from retinal tears only partially overlaps with that presenting with lattice degeneration of the retinal periphery, and that it is questionable if a causal link is present between these two conditions. As a result the raison d'etre of prophylaxis can be called into question. PMID- 6903432 TI - The effect of acetyl-salicylic-acid pretreatment on re-formed aqueous humor. A study of intracapsular lens extraction in the human eye. AB - Aqueous humor (a.h.) was sampled in 67 patients operated on for cataract by intracapsular lens extraction at the start and finish of surgery. Twenty eight of these patients received pretreatment with acetyl-salicylic acid (ASA), to a total of 2.5 g, beginning 18 hours prior to surgery. A serum sample was drawn immediately following the operation from 55 patients. Using radial immunodiffusion, albumin and IgG were measured in primary and secondary a.h. and in serum. The group pretreated with ASA showed a significantly smaller relative increase of IgG (P < 0.05). The increase of the proteins, however, showed no dependence on their serum-level and the only side-effect of the treatment was an unexplained rise in serum-albumin. The possible clinical application of patients with a high risk of postoperative complications is briefly summarized. PMID- 6903433 TI - Cataract Surgery: types and frequencies of complications. AB - A total of 4,300 cataract extractions were evaluated with respect to operative complications and their effects on postoperative visual function. Severe vision threatening complications such as vitreous or expulsive hemorrhage occurred in 6 of the 4,300 eyes; 726 eyes followed up over 1--3 years showed late complications in 0.44%--1.77%. The relevance of the date prior to surgery is discussed. PMID- 6903434 TI - Bactericidal synergy between penicillin or ampicillin and aminoglycosides against antibiotic-tolerant lactobacilli. AB - The bactericidal activities of penicillin G and ampicillin alone were compared with those of their combinations with streptomycin or gentamicin against 17 strains of lactobacilli classified as tolerant to various beta-lactam antibiotics. The penicillin G combinations with streptomycin and gentamicin were synergistic against 17 and 16 of these strains, respectively, whereas the corresponding ampicillin-aminoglycoside combinations were synergistic against 12 and 15 strains, respectively. Importantly, synergy was manifested at concentrations of these antibiotics that are attained in serum after their administration in conventional dose regimens. In no instances were combinations antagonistic. These in vitro observations provide a partial explanation for the favorable results obtained in preliminary clinical evaluations of the benefits of combination regimens in the treatment of lactobacillus infections refractory to single-drug therapy. PMID- 6903435 TI - Bioassay of antibiotics in body fluids from patients receiving cancer chemotherapeutic agents. AB - Patients receiving antitumor chemotherapy are at increased risk of developing nosocomial infections, and the antibacterial therapy of such infections is often monitored by bioassay. The effect of antitumor agents on seven bioassay procedures using strains of Sarcina, Klebsiella, Clostridium, Pseudomonas, Staphylococcus aureus, and S. epidermidis or Bacillus was evaluated. The minimum inhibitory concentrations of six antitumor drugs, cytarabine, dactinomycin, doxorubicin, 5-fluorouracil, methotrexate, and vinblastine, determined for each of the test organisms, showed that 5-fluorouracil, dactinomycin, and doxorubicin are used at blood levels sufficient to interfere with bioassay procedures. The other drugs have minimum inhibitory concentrations as much as 100 times the expected blood levels. Antibiotic (gentamicin, kanamycin, cephalothin, and carbenicillin) recovery experiments in the presence of therapeutic levels of antitumor agents showed no in vitro inactivation of antibiotic. However, at low cephalothin concentrations (less than 20 microgram/ml) in the presnce of 5 fluorouracil, bioassay results were in error by as much as 100%. The data indicate that bioassay procedures for the determining of antibacterial drug levels may need to be modified for those patients receiving antitumor therapy with 5-fluorouracil, doxorubicin, or dactinomycin. PMID- 6903436 TI - Penicillin-binding proteins of multiply antibiotic-resistant South African strains of Streptococcus pneumoniae. AB - Multiply drug-resistant South African pneumococci (with penicillin minimal inhibitory concentrations ranging from 0.2 to 12.5 microgram/ml) showed several types of major alterations in their penicillin-binding protein (PBP) pattern compared with that of a penicillin-susceptible laboratory strain of Streptococcus pneumoniae (R6; penicillin minimal inhibitory concentration = 0.006 microgram/ml). Genetic transformants were obtained by using South African pneumococcus (strain 8249) deoxyribonucleic acid as donor and the competent cells of strain R6 as recipient; seven classes of transformants with progressively higher penicillin resistance were isolated, and their PBPs were tested. The PBP patterns exhibited a gradual shift from a pattern similar to that of the recipient to a pattern resembling that of the donor strain as the level of penicillin resistance increased. PMID- 6903437 TI - Penicillin-binding components of penicillin-susceptible and -resistant strains of Streptococcus pneumoniae. AB - Three strains of Streptococcus pneumoniae with low-level resistance to penicillin, one strain with resistance to penicillin, and three strains susceptible to penicillin were compared. The three susceptible strains had very similar patterns of penicillin-binding components (PBCs) as detected by fluorography after sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Gels of these strains showed four major bands and a single minor band. All of the resistant strains showed different PBC patterns from those obtained for susceptible strains. The most marked changes were observed with the most resistant strain SPR110, which showed markedly reduced intensity of PBC 3 and a reduction in intensity of PBCs 1 and 2, as well as additional bands in the region of band 2. Low-level resistant strains had band densities different from the susceptible strains principally for PBC 3. No beta-lactamase activity or plasmid was detected in the resistant strains. An apparent difference in affinity for cloxacillin was also demonstrated between some of the PBCs of susceptible strain S. pneumoniae SPS101 and resistant strain S. pneumoniae SPR110. Penicillin resistance in the low-level resistant and the resistant strains was associated with PBCs possessing different properties from those seen in the three susceptible strains. Reduction in affinity for penicillin or a reduction in the amount of a PBC protein, or both, are the probable explanations of penicillin resistance in these strains. PMID- 6903438 TI - [Effect of antibiotic therapy in the mother on the colonization of the newborn by enterobacteriaceae (author's transl)]. AB - Two studies were undertaken to determine the effect of antibiotic therapy in the mother on the enterobacteriaceae of the newborn's fecal flora. In the first, mothers were given tetracycline after delivery. Although the effect on the maternal flora was important there was no noticeable effect on the enterobacteriaceae of the newborn although the organisms were predominantly susceptible. In the second, mothers were given ampicillin before delivery and resistant enterobacteriaceae were predominant in all the newborns. In the controls born to untreated mothers susceptible organism still predominate. Antibiotic treatment of the mother has an important effect on the newborn's flora if the treatment is given before delivery. PMID- 6903439 TI - Stress and the working mother. PMID- 6903440 TI - Rejection of Government statement on nursing education. PMID- 6903441 TI - A letter from America. PMID- 6903442 TI - Prazosin hydrochloride. PMID- 6903443 TI - Overseas experiences and trends in primary health care. PMID- 6903444 TI - Implementation of a quality assurance programme in community nursing. PMID- 6903445 TI - Conceptual models for teaching: a current examination. PMID- 6903446 TI - Treatment of snake bite in Australia and P.N.G. PMID- 6903448 TI - Clinical review a rationale. PMID- 6903447 TI - Kampuchean refugees--an encounter with grief. PMID- 6903449 TI - Activation of the alternative pathway of complement by microcrystalline cholesterol. AB - Microcrystalline cholesterol in either the anhydrous or monohydrate form was a potent activator of the alternative pathway of complement as measured by the electrophoretic conversion (crossed immunoelectrophoresis) of C3 and properdin factor B. Chelation with 0.01 M ethylene-diaminetetraacetate (EDTA) completely eliminated conversion, but 0.01 M ethyleneglycol tetraacetate (EGTA) had little or no effect. The magnitude of activation by cholesterol crystals was similar to that by zymosan, heat-aggregated IgG, or crystals of monosodium urate monohydrate. The microcrystalline forms of the acetate, linoleate, or oleate esters of cholesterol did not activate more complement than did saline controls. Cholestanol retained full C3 activating potency, but cholestane had none. Binding of IgG by cholesterol monohydrate is very small compared to that by sodium urate. PMID- 6903450 TI - Purification and characterization of the elastase-like enzyme of the bovine granulocyte. AB - The extracts of granules isolated from bovine granulocytes show elastase- and chymotrypsin-like activities, as detected with specific synthetic substrates. Extraction of these enzymes depends upon salt concentration. In the course of the present studies a 21-fold purification of the elastase-like enzyme was achieved on a (Ala)3-CH-Sepharose 4B gel. The molecular weight of the enzyme is 33 000, as determined by gel electrophoresis in the presence of sodium dodecyl sulfate. The elastase-like activity is inhibited by phenylmethylsulfonyl fluoride, soybean trypsin inhibitor, basic pancreatic inhibitor and by heparin at different rates. Elastatinal inhibits the enzyme competitively (Ki = 80 microM). The cytosol of bovine granulocytes contains a protein which strongly inhibits the elastase-like enzyme of the bovine granulocyte (Ki = 0.4 nM) as well as porcine pancreatic elastase (Ki = 11 nM). PMID- 6903451 TI - [Elastase activity in experimental pancreatitis]. AB - The activity of elastase, elastase inhibitor and isozymes of lactate dehydrogenase (LDH) was studied in 11 dogs with experimental pancreatitis and 5 control dogs. All dogs with experimental pancreatitis died 6--14 hours after the induction of pancreatitis. Morbid anatomy studies proved severe pancreonecrosis. The results obtained show that after the induction of pancreatitis the elastase blood activity increased 3-fold as compared with the initial level, and remained unchanged up to the animals' death. At the same time the activity of elastase inhibitor fell, correlating with the rise in elastase activity. Also there was a disproportion between LDH 1 and LDH 2 which became more conspicuous to the 3d hour, and an increase in LDH 5 by the end of the experiment. A conclusion is made that dysfunction of the liver may be one of the causes of the decreased inhibitory activity of elastase in pancreonecrosis. PMID- 6903453 TI - Skilled anesthesia is often key figure during surgery. PMID- 6903452 TI - Depletion of epinephrine in rat hypothalamus by Ro 4-1284: influence of pargyline and harmaline. AB - Ro 4-1284, 2-ethyl-2,3,4,6,7,11b-hexahydro-3 isobutyl-9,10-dimethoxy-2H benzo[a]quinolizin-2-ol hydrochloride, depleted epinephrine in rat hypothalamus; the depletion occurred within 1 hr and persisted at 24 hr. The rapid lowering of epinephrine by Ro 4-1284 was antagonized by pargyline, a monoamine oxidase inhibitor, which alone elevated epinephrine concentration. The ability of pargyline to antagonize epinephrine depletion by Ro 4-1284 was prevented by co treatment with harmaline, which protects aginst type A but not type B monoamine oxidase inhibition by pargyline. Pargyline also antagonized the Ro 4-1284-induced depletion of norepinephrine in hypothalamus and of norepinephrine and dopamine in cerebral hemispheres, and these effects of pargyline were also prevented by co treatment with harmaline. The results suggest that epinephrine in rat brain, like norepinephrine and dopamine, is destroyed primarily by type A monoamine oxidase. PMID- 6903454 TI - Professional liability newsletter: a 400,000 dollar settlement for death from dental anesthesia. PMID- 6903455 TI - Use of the esophageal obturator airway with a report of an unusual complication. PMID- 6903456 TI - Background narrative script. The film: "A different kind of nurse.". PMID- 6903457 TI - Professional liability newsletter: an anesthesia death. PMID- 6903458 TI - You and the law. "Nurse, you did this to me! It's your fault!". PMID- 6903460 TI - Use? or abuse? PMID- 6903459 TI - Drug abuse: perspective--a health-oriented approach. PMID- 6903461 TI - It could happen to you. PMID- 6903462 TI - A learning program in the addictions. PMID- 6903463 TI - Dangerous equations: drugs and carelessness add up to danger. PMID- 6903464 TI - Gasoline inhalation: a community challenge. PMID- 6903465 TI - Dealing with the disruptive patient. PMID- 6903466 TI - The drug abusing patient in the ER. PMID- 6903467 TI - Primary nursing: treatment that works for the hospitalized drug dependent client. PMID- 6903468 TI - Breaking the cycle of abuse. PMID- 6903469 TI - Living and working with drugs. PMID- 6903470 TI - Understanding the physiology of alcohol abuse. PMID- 6903471 TI - AWS: recognition and rehabilitation. PMID- 6903472 TI - Information exchange. PMID- 6903473 TI - Oral hygiene measures for patients with cancer. II. PMID- 6903474 TI - Use of therapeutic play in the ambulatory pediatric hematology clinic. PMID- 6903475 TI - Factors that impact data collection from children. PMID- 6903476 TI - The association of numerous life changes with cervical dysplasia and metaplasia. PMID- 6903477 TI - Reexamining the dietary restrictions with procarbazine (an MAOI). PMID- 6903478 TI - Nursing research: new definitions, collegial approaches. PMID- 6903479 TI - Programmed instruction: cancer care. Immunology. PMID- 6903480 TI - Cancer nursing and the law: informed refusal. Part IV. PMID- 6903481 TI - INA presents views on the nursing shortage. PMID- 6903482 TI - 1980 INA/AJN Essay Contest Winner. Don't hesitate: you have a lot going for you! PMID- 6903483 TI - [For future nurses: correspondence between Ms. Masu Yumaki and Rosemary Ellis]. PMID- 6903484 TI - [This I believe--about questioning the right to die]. PMID- 6903485 TI - [Nursing process. 1--Its theoretical background]. PMID- 6903487 TI - [Sensitivity to perceive the patient accurately--trial by case conference at Yokohamaa Shimin Hospital]. PMID- 6903486 TI - ["Nursing theory: notes on lectures"--a discussion with Prof. Hiroko Usui]. PMID- 6903488 TI - [Transition to a new nursing system]. PMID- 6903489 TI - [Need for constant gentleness and cheerfulness--a message to nursing students]. PMID- 6903490 TI - Growing up with deafness. PMID- 6903491 TI - Health visiting priorities. PMID- 6903492 TI - More than just physical care. PMID- 6903493 TI - Hearing tests on twins. PMID- 6903494 TI - Bacitracin therapy in antibiotic-associated pseudomembranous colitis. AB - Two patients with antibiotic-associated pseudomembranous colitis, and stool positive for Clostridium difficile cytotoxin were successfully treated with oral bacitracin. One patient had previously suffered two relapses of pseudomembranous colitis following successful treatment with vancomycin and one patient was allergic to vancomycin. Bacitracin appears to be a reasonable choice to treat patients with antibiotic-associated colitis who are allergic to vancomycin. Further studies comparing vancomycin and bacitracin are needed. PMID- 6903495 TI - [Comparison of activity of fosfomycin, oxacillin and penicillin G against staphylococci and micrococci (author's transl)]. AB - The in vitro sensitivity against fosfomycin, oxacillin and penicillin G was tested in 65 Staphylococcus aureus strains, 71 coagulase negative staphylococci and 46 micrococci. Fosfomycin was very effective against staphylococci. Cross resistance with simultaneously tested penicillins could not be demonstrated. Fosfomycin was only partially effective against micrococci for which penicillin G was most effective. PMID- 6903496 TI - [Inflammatory diseases of the female genitalia]. PMID- 6903497 TI - [Diagnosis and management of labor in placental presentation]. PMID- 6903498 TI - [Medical and genetic counseling for families with hereditary diseases]. PMID- 6903499 TI - [Urolithiasis]. PMID- 6903500 TI - [Public organized for the 1980 Olympics]. PMID- 6903501 TI - [Neurodermatitis]. PMID- 6903502 TI - [Side effects of antibiotics]. PMID- 6903503 TI - [Acute carbon monoxide poisoning]. PMID- 6903504 TI - [Drugs with primary central nervous system action]. PMID- 6903506 TI - [Medical service at sports competitions]. PMID- 6903505 TI - [Psychotropic drugs in out-patient practice]. PMID- 6903507 TI - [Competition for best in the profession among the paramedical workers of epidemiological health institutions]. PMID- 6903508 TI - [Exacerbation of bilateral inflammation of the uterine adnexa and dysfunctional uterine hemorrhage]. PMID- 6903509 TI - [Improved bottle for feeding nursing infants]. PMID- 6903510 TI - [Role of individual transmission factors in the spread of intestinal infections]. PMID- 6903511 TI - [Effect of the kinin system on adrenal cortical hormonal function]. PMID- 6903512 TI - Are HLA types or Bf alleles markers for diabetic retinopathy? PMID- 6903513 TI - From custodial care in a state hospital to therapeutic nursing. PMID- 6903514 TI - Patient-administered drugs in a municipal hospital. PMID- 6903515 TI - Putting down roots in retirement. PMID- 6903516 TI - Photography in a nursing home. PMID- 6903517 TI - "Who's confused here"? PMID- 6903518 TI - Hamlet dweller--city dweller. PMID- 6903519 TI - Interrupting the depression cycle. PMID- 6903520 TI - Transportation: how do senior citizens get around? PMID- 6903521 TI - Nutrition: What can you learn from labels? PMID- 6903522 TI - How do digitalis tolerance and toxicity change with age? PMID- 6903523 TI - 70+ and going strong. PMID- 6903524 TI - Ombudsman for all. How to negotiate the hospital system for patients in trouble. PMID- 6903525 TI - Act your age! Does this command haunt us all our lives no matter how young we feel? PMID- 6903526 TI - Foot problems and assessment. PMID- 6903527 TI - Health screening in Hawaii. PMID- 6903528 TI - Annie. "Uncooperative?" "Confused?" Not by a long shot, when she had a nurse who really listened. PMID- 6903529 TI - Touching is not taboo. PMID- 6903530 TI - Caring: nursing's promise to the elderly. PMID- 6903531 TI - Older wiser learners. PMID- 6903532 TI - Medications that contain sodium. PMID- 6903533 TI - A high carbohydrate diet for the person with diabetes? PMID- 6903534 TI - Promoting urine control in older adults. Scope of the problem. PMID- 6903535 TI - Urinary continence/incontinence. Assessing the problem. PMID- 6903536 TI - Nursing care for the incontinent person. PMID- 6903537 TI - Urinary continence/incontinence. Strengthening pelvic floor muscles. PMID- 6903538 TI - Urinary continence/incontinence. Habit retraining: a tested method to regain urinary control. PMID- 6903539 TI - Urinary continence/incontinence. Recognizing warning time: a critical step toward continence. PMID- 6903540 TI - Urinary continence/incontinence. Modifying behavior at home: a team effort. PMID- 6903542 TI - Urinary continence/incontinence. Helpful equipment: what' s available to make life pleasanter for patients and staff. PMID- 6903541 TI - Urethral catheterization. Pros and cons of an invasive but sometimes essential procedure. PMID- 6903543 TI - Urinary continence/incontinence. Helpful drugs: depending on the cause of incontinence, medication may be the answer. PMID- 6903544 TI - Urinary continence/incontinence. Nursing implications of drug therapy. Close observation for both expected and unexpected effects is a must. PMID- 6903545 TI - Advocacy or control: which do we offer the elderly? PMID- 6903546 TI - How risky is self-care with OTC medicines? PMID- 6903547 TI - Vitamins--what's fiction? What's fact? PMID- 6903548 TI - [Changes of signs and delusional behaviour in aged chronic schizophrenics (author's transl)]. PMID- 6903549 TI - [Recent aspects of the suicide problem (author's transl)]. AB - The problem of suicide is linked not only with psychiatric and psychological aspects, but also with sociological, ethical and legal, philosophical and theological problems. Significantly results of suicide research are represented by the psychoanalytic aspects of suicide as a conflict of aggression and narcissistic crisis, as well as by the description of the "presuicidal syndrome" (Ringel) and the structural analysis of the suicidal event. Today, suicidal syndromes are strikingly frequent among adolescents, the aged, drug addicts, dipsomaniacs and alcohol and other addicts in general as well as among psychotic patients. It is often particularly difficult to assess suicidality. Quite frequently the suicidal patient taxes the therapist's resources to a very high degree. Prevention of suicide must be considered as an important psychiatric and social challenge; the goal should be to correct the inner attitude of the person concerned and to influence and change the conditioning factors of the social environment. All preventive measures can be considered meaningful and justified only if they are directed not only at the preservation of life but also at the quality of the life led by the persons considered as suicide risks. PMID- 6903550 TI - [Psychosocial influences on the success of therapy in epileptic children (author's transl)]. PMID- 6903551 TI - [A disease pattern simulating a cubitocarpal "double-tunnel" syndrome due to anastomosis after Martin-Gruber (author's transl)]. AB - The article reports on a case which appeared as though two tunnel syndromes were present simultaneously, namely, the cubital and the carpal tunnel syndromes. Thorough electrophysiological examination revealed, however, that this simulated pattern was due to the presence of an anastomosis after Martin-Gruber. Three months after surgery the patient was free from symptoms. Intraoperative neurography had established the compression and its resolution. Anastomosis of Riche-Canieu was an additional, secondary finding. PMID- 6903553 TI - [What does the psychiatrist expect as to computerized tomography? (author's transl)]. PMID- 6903552 TI - [Mortality in hospitalized psychiatric patients (results from a 5-year study) (author's transl)]. AB - During 5 years we have registered mortality in 1239 chronic hospitalized psychiatric patients (609 men and 630 women) aged between 40-70 years in 6 German hospitals. We examined this patients on incidence of cardial riskfactors. The death rates were compared to the others of BRD. In this connection we found out an intensified mortality in all age groups of psychiatric patients as against to BRD average. The mortality of respiratory system diseases surpassed death rates of BRD many times better. Also psychiatric patients died by cardiovascular diseases more than expected. The death rates from ischaemic heart diseases in men were approximately twice as much than at BRD statistic. Patients who died in arteriosclerotic diseases had more often riskfactors than the other deceased. The great number of sudden and unexpected deaths was remarkable. PMID- 6903554 TI - [Hemodialysis in patients with chronic schizophrenia (author's transl)]. AB - In an open study three chronically schizophrenic patients with normal kidney function were treated by hemodialysis in an attempt to ameliorate their psychotic symptoms. Neuroleptic treatment was stopped at least four weeks prior to hemodialysis. The patients were dialysed once weekly for twelve (in one case eleven) weeks. Psychopathology was evaluated using the IMPS, BPRS and NOSIE. No patient showed any improvement during the course of dialysis, one patient showed a marked detrioration. These observations raise doubts about whether schizophrenic psychoses can be improved by means of hemodialysis as previously published by Wagemaker (1977). PMID- 6903555 TI - [In what way can the clinical usefulness of the Wechslers-Bellevue test for general knowledge be improved for the testing of neuropsychiatric patients? An attempt at revalidation (author's transl)]. AB - Questions related to general knowledge were adapted to the mental capacity of neuropsychiatric patients by means of regrouping and suitable modifications. The sequence of items according to the degree of difficulty, enables a more profitable use of the Wechsler-Bellevue test, since the questions relating to general knowledge need not begin with Question No. 1. The general knowledge subtest was changed into a psychopathometric method by means of an item analysis. In this manner, it is more adequately adapted to the mental capacities of neuropsychiatric patients. Moreover, irregular distribution of data which have not yet been evaluated and classified, is avoided, so that the intellectual performance of the patient can be explored in a fairer manner than before. PMID- 6903556 TI - The hemolytic equivalence of human, guinea pig and canine complement proteins. AB - The ability of functionally pure human, guinea pig and canine complement proteins to fulfill the hemolytic function of a substituted analagous component in an otherwise totally homogeneous complement sequence was investigated by means of conventional hemolytic assays. A striking feature was the observation that for hemolysis to occur, differing requirements for enzyme-substrate homology were exhibited by each of the three species of C3 and C5 convertases (C3 and C5 CVA). The results suggest that different strategies of molecular interaction evolved in complement systems of different species. PMID- 6903557 TI - Stabilization of the classical pathway C3 convertase C42, by a factor F-42, isolated from serum of patients with systemic lupus erythematosus. AB - Sera from sixteen patients with SLE were investigated for the presence of a factor which would conserve convertase activity on preformed EAClgp 4hu2hu for 30 min at 30 degrees in EDTA. Although such a factor could not be detected readily in the sera, chromatography on DE-52 cellulose yielded fractions appearing as three peaks in one patient and as two peaks in a second patient. These peaks were capable of conserving C42 activity and were designated as F-42. Purification of F 42 from the second peak eluting between 4 and 7 mS on DE-52 was obtained by SP C50, S-300 and QAE-A50 chromatography. F-42 exhibited charge heterogeneity upon SP-C50 chromatography. On polyacrylamide gel electrophoresis the final material migrated as one band, which coincided with the position of F-42 activity upon eluation from a parallel gel. F-42 had an apparent molecular weight of 150,000 and reacted with anti-IgG in Ouchterlony analysis. Sepharose-bound anti-IgG was capable of neutralizing F-42 activity. The purified material was shown to prolong the half-life (T 1/2) of performed cell-bound C42 in GVB-EDTA at 30 degrees from 5 to 80 min. PMID- 6903558 TI - Increased biosynthesis of complement components by cultured monocytes, synovial fluid macrophages and skynovial membrane cells from patients with rheumatoid arthritis. AB - Monocytes, synovial fluid (SF) and synovial membrane (SM) macrophages from patients with rheumatoid arthritis (RA) were maintained in short-term tissue culture for up to 10 days, and the synthesis of C4, C2, C3, C5, factor B(B), D, properdin (P), C3b inactivator (C3bINA) and beta 1H globulin studied. Functionally active C2, B, D, P, C3bINA and beta 1H were synthesized by the cells in each type of culture. C4, C3 and C5 could be detected, but were functionally inactive. RA monocytes synthesized more C2 than monocytes from patients with degenerative joint disease (DJD) (P < 0.001). Similar studies revealed that SF macrophages synthesized more C3 than SM macrophages (P < 0.001) which in turn produced more C2 than monocytes (P < 0.001). Other experiments showed that SF macrophages synthesized more of each component than the other cell types. SM macrophages made more C2 than B than RA and DJD monocytes, but synthesized only small quantities of P, D and beta 1H. RA monocytes synthesized more of each component than DJD monocytes. The results of these studies show that (1) in RA, complement components can be synthesized locally in the inflamed joints, and (2) local factors in the joints probably stimulate complement synthesis. PMID- 6903560 TI - Differences in importance ratings of self-care geriatric patients and the nurses who care for them. PMID- 6903561 TI - Correlation between the quality patient care scale and the Phaneuf audit. PMID- 6903559 TI - Alterations in serum opsonic activity and complement levels in pneumococcal disease. AB - Pneumococcal opsonic activity and concentrations of pneumococcal capsular polysaccharide antigen, C3, C4 factor B, C3 and factor B breakdown products were measured in the serum obtained acutely from 12 patients with serious pneumococcal disease. One patient showed markedly reduced pneumococcal opsonic activity, borderline-low C3, and the presence of C3 and factor B breakdown products and died. Although eight additional patients showed depressed levels of C3 or C4 or the presence of C3 or factor B breakdown products, none had reduced pneumococcal opsonic activity. All of the three remaining patients had normal opsonic activity and C3 and C4 levels. Covalescent serum was obtained from eight patients; six had normal C3 and C4 levels, and two had persistent C4 depression. These data show that complement is activated during pneumococcal disease and suggest that extensive complement activation may impair pneumococcal opsonic activity in certain patients and thereby compromise an important host defense mechanism. PMID- 6903562 TI - Exploration of student nurses' stereotypes of patients. PMID- 6903563 TI - Towards the development of an operational definition of the concept "therapeutic use of self". PMID- 6903564 TI - The status of nurses' knowledge and beliefs about autism. PMID- 6903565 TI - Community psychiatric nursing--a literature review. PMID- 6903566 TI - Human relations in the hospital setting: a critical analysis. PMID- 6903567 TI - The expanded role of the nurse in the Caribbean. PMID- 6903568 TI - Nursing: a social service--considerations for nursing administration. PMID- 6903569 TI - Patients' perceptions of time: current research. PMID- 6903570 TI - The family clinic--an experiment in primary health care in Nigeria. PMID- 6903571 TI - Improvement of the productivity of elasnin, a specific elastase inhibitor, by Streptomyces noboritoensis KM-2753. AB - Streptomyces noboritoensis KM-2753, an elasnin-producing strain, co-produces an antimycin complex and its elasnin productivity is low (0.006 mg/ml). To obtain mutants possessing higher degrees of elasnin productivity and deficient in antimycin production, the strain was treated with N-methyl-N'-nitro-N nitrosoguanidine (NTG), ultraviolet light, acriflavine (AF) and high temperature. Mutant N-134 obtained by treatment with NTG was 108 times higher than the original strain in elasnin productivity and produced no antimycin. Strain AF-17 obtained by AF treatment and strain H-80 obtained by incubation at high temperature showed 715 and 428 times higher productivities than that of the original strain, respectively. The productivity of elasnin was further increased 1.6 approximately 2.6 times by addition of saturated fatty acids, especially lauric acid, to the culture. Consequently, strain AF-17 produced 11.1 mg/ml of elasnin in the presence of 10 microgram/ml of lauric acid. PMID- 6903572 TI - Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase. AB - Compactin (ML-236B) and the related compound, mevinolin, are competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG CoA reductase), the rate-controlling enzyme in cholesterol synthesis. Previous studies have shown that administration of compactin to cultured cells elicits a compensatory increase in the amount of HMG CoA reductase in the cells. A similar increase in HMG CoA reductase has been reported in livers of rats and mice that have been treated with compactin. In this study, we explore the mechanism for the mevinolin-mediated increase in hepatic HMG CoA reductase in mice that have been fed a control diet and a 2% cholesterol diet. Administration of mevinolin to mice on a control diet produced a 6- to 10-fold increase in the amount of HMG CoA reductase in liver microsomes. When mice were fed the cholesterol-enriched diet, cholesterol accumulated in the liver and HMG CoA reductase declined by 90%. The administration of mevinolin to cholesterol-fed mice produced a three to eightfold increase in HMG CoA reductase. Despite the abundant amount of cholesterol that was already present in the livers of the mevinolin-treated, cholesterol-fed animals, their elevated HMG CoA reductase could be rapidly suppressed by the subcutaneous injection of small amounts of mevalonate, the product of HMG CoA reductase. These data are compatible with the existence in mouse liver of a multivalent feedback regulatory mechanism for HMG CoA reductase in which suppression of the enzyme requires both a sterol and a nonsterol substance derived from mevalonate. By blocking mevalonate synthesis, mevinolin activates this regulatory mechanism, and this in turn causes an increase in hepatic HMG CoA reductase. The ability to suppress the elevated HMG CoA reductase with mevalonate may prove useful in potentiating the effectiveness of mevinolin as a hypocholesterolemic agent. PMID- 6903573 TI - Hospital sisters: work attitudes, perceptions and wastage. AB - This study attempts to describe the attitudes and perceptions that hospital sisters have towards their work and the relationship, if any, of these attitudes and perceptions to absence, leaving intent and wastage. The theoretical approach adopted was based on the Minnesota Theory of Work Adjustment and the role stress theory originally developed at the University of Michigan, and the measures used included rating scales developed in these centres. The results indicated that most of the sisters were, in general, satisfied with their jobs, although a substantial minority were dissatisfied with and experienced role conflict and ambiguity from certain features of their working environment. Comparison of the leavers with the stayers revealed no difference between the groups on intrinsic satisfaction, absence and role ambiguity, but the leavers were less satisfied with extrinsic features of the job, and experienced more tension and role conflict than the stayers. The fairly strong 'mobility culture' reported by other research was supported and it was tentatively concluded that after a year or two, the job fails to provide the sister with sufficient challenge, and her propensity is to leave for more stimulating work. The implications of this conclusion are discussed. PMID- 6903574 TI - Imogene King's conceptual framework: a proposed model for continuing nursing education. AB - This paper presents a proposed model for continuing nursing education based on Imogene King's conceptual framework. The rationale for using King's conceptual framework as the foundation underlying this proposed model is three-fold: the concepts--social systems, health, perception, and interpersonal relationships- are relevant in every nursing situation; the interacting levels of operation- individuals, groups, and society--depict a reciprocal relationship between human behaviour and the environment; and the triad of elements--continuing nursing education, nursing practice, and nursing research--are interrelated in the nursing profession. The authors contend that this approach to continuing nursing education is beneficial to participating nurses, the health care consumer, and to the advancement of the nursing profession. Based on its simplicity and flexibility, the proposed intra-systems model described in this article is useful as a systematic guide for continuing nursing education. The authors believe that this proposed model provides an approach for stimulating continued learning, for establishing innovative foundations for nursing practice, and for generating inquiry through research. Utilizing this approach in maintaining the educational standards for professional practice will promote change for the advancement of the nursing profession. PMID- 6903575 TI - A case for community psychiatric nurses. AB - The author reviews the development of community psychiatric nursing services since the Mental Health Act 1959. In particular, the community services to her own catchment population are discussed, analysed and evaluated. A claim is made that community care is cost-effective and makes a contribution to prevention. It is also agreed that the presence of community psychiatric nurses in the community fosters greater tolerance and acceptance of the mentally sick by the community at large. PMID- 6903576 TI - Some aspects of the teaching and learning of nursing. AB - The argument on which this paper is based is that the activities of teaching and learning nursing draw on a number of disciplines and fields of knowledge. To support this argument, elements in the process of teaching and learning in nursing are set out and each one is analysed and discussed. The elements so analysed are later put together to give a synthesis of the intended outcomes of the process of nursing education. The paper is supported with an extensive bibliography. PMID- 6903577 TI - The effectiveness of clinical teaching: a model for self-evaluation. AB - The most widely used process for evaluating teachers' effectiveness is student ratings. Although student ratings of teachers are vitally important in the evaluation process, self-evaluation and that of peers are equally important in accurately defining an individual's effectiveness in his/her teaching role. The model for self-evaluation of clinical teaching presented in this paper is adapted from the analysis in Jacobson's model of instruction evaluation. This model comprises three steps: the pre-active, interactive, and post-active. The pre active step in clinical teaching includes such activities as preparing objectives for both teacher and students, and communicating them to the students before clinical practice. The interactive step in clinical teaching may be seen as the actual process of teaching in the clinical area, with its central activity as being the preparation and presentation of clinical assignments to the students. It is in this step when the teacher-student relationship is put to a real test. The post-active step is a process for finding out the extent to which the teacher has achieved the desired results. This step also entails such activities as grading assignments, evaluating students' clinical performance, and conducting post-experience clinical conference. A check list for self-evaluation of clinical teaching is included. PMID- 6903578 TI - Overseas nurses--effective therapeutic agents? AB - Factors affecting the effectiveness of overseas people employed as psychiatric nurses are discussed. Basic cultural influences, especially different value systems between the immigrant and the host population, are seen as unlikely to be greatly altered by the environment in which the immigrant nurses find themselves. In fact a greater divergence would seem more likely to occur. The different experiences of immigrant nurses compared with nurses recruited in Britain are considered under the following headings: expectations of the immigrants on entering nursing, their contact with the host culture, the reaction of the indigenous population to the immigrant, language difficulties, and the insecurity of employment. The conclusion drawn is that the cultural differences, recruitment methods, the immigrants' experiences in employment and lack of contact with the culture of the indigenous population (apart from their deviant members) are likely to adversely affect his/her ability to function as a therapeutic agent. This is particularly important where the form of treatment is based on the social model. PMID- 6903579 TI - Relative resistance of the F-42-stabilized classical pathway C3 convertase to inactivation by C4-binding protein. AB - The sera of some patients with SLE contain an IgG antibody (F-42) directed against the classical pathway C3 convertase (C-42), which is capable of stabilizing C42 in a dose-dependent manner. The half-life (T 1/2) of C42 is prolonged by F-42. In order to determine whether C4-binding protein was capable of reversing stabilization of C42, stabilized and unstabilized cell-bound C42 were exposed to purified C4-bp and the convertase activity was assessed. C4-bp was capable of accelerating the decay of C42 in a dose-dependent manner; 2 microgram/ml C4-bp reduced the T 1/2 of C42 from 5 to 2.5 min at 30 degrees C. On the other hand, 16 microgram C4-bp could reverse stabilization of C42 by F-42 from T 1/2 = 78 min to a T 1/2 - 40 min; 128 microgram C4-bp reduced the T 1/2 of stabilized C42 to 4 min. Functional inactivation of C42 occurs via enhanced decay dissociation of C2 from the convertase by C4-bp, as shown by the release of 125I C2i from the cell-bound convertase. Stabilization of C42 by F-42 is caused by prevention of decay-dissociation of 125I-C2. F-42 was also capable of stabilizing C4oxy2 even further, as shown by prolongation of the T 1/2 of cell-bound C4 oxy2 to a T 1/2 of at least 300 min at 30 degrees C. PMID- 6903580 TI - Administering the contract. AB - Administering the collective bargaining contract is a challenging and important nursing administration responsibility. This article discusses the attitudes, skills, and strategies that the nursing administrator who manages a unionized professional staff can use to minimize employee grievances and foster a professional practice climate. Directors of nursing in nonunionized settings also can use these guidelines to maintain the union-free status of their departments. PMID- 6903581 TI - Performance appraisal is not enough. AB - The authors suggest that performance planning and appraisal is a cooperative venture between you and your employees based on a genuine concern for each other's success. In this article they outline a performance appraisal approach that includes advance agreement between you and your employee about what is to be accomplished. Their advice will help you design a performance appraisal system that encourages employee participation and goal achievement. PMID- 6903582 TI - A review of organizational development. AB - Organizational development (OD) stresses the involvement of staff members in improving organizational effectiveness. It is a management strategy well-suited to the people-intentive hospital organization. This review of OD, its principles and objectives, the assumptions underlying its use, and the conditions necessary for success provides a picture of its application in the hospital. PMID- 6903583 TI - Essential skills for baccalaureate graduates: perspectives of education and service. AB - What psychomotor tasks should baccalaureate graduates be able to perform when they arrive on the doorsteps of practice settings? This article describes a research study in which a representative sample of nursing educators and nursing service personnel provide their perceptions in regard to that question. The content offers a clear view of the expectations of both groups, emphasizes the need for dialogue on this topic between educational service, and raises important issues for nursing administrators regarding the role of staff development and the transition of new graduates to the work setting. PMID- 6903584 TI - Mastering the people skills. PMID- 6903585 TI - Marketing nursing research. PMID- 6903586 TI - Mediation--what it is, what it does. PMID- 6903587 TI - Nursing consultation: a collaborative process. PMID- 6903588 TI - Stressed but satisfied: organizational change in ambulatory care. PMID- 6903589 TI - Nurses as health planners. AB - Nursing leaders have the knowledge and responsibility to serve on the boards of health planning agencies. This article provides suggestions and strategies for developing your role as an active and articulate member of a health systems agency. PMID- 6903590 TI - The ins and outs of collective bargaining. AB - Negotiation of a collective bargaining agreement requires knowledge and preparation. This article outlines considerations and strategies for nursing administrators who are about to participate in labor negotiations. A "how-to" focus is presented by the author, an attorney who represents major hospitals in labor negotiations. PMID- 6903591 TI - Management by whose objectives? PMID- 6903592 TI - Education for nursing administration: what investment yields highest returns? PMID- 6903593 TI - Burnout: assessment and intervention. PMID- 6903595 TI - Food fads and the elderly. PMID- 6903594 TI - Atypical cilia in rabbit bronchial epithelial cells induced by elastase: an ultrastructural study. AB - Ultrastructural study of the bronchial epithelium of elastase-treated rabbits revealed the presence of luminal atypical cilia resembling the pathological cilia seen in the tracheobronchial epithelium in animal models of human lung cancer. It is suggested that the results may contribute to knowledge of the mechanisms whereby compound cilia are produced. PMID- 6903596 TI - Today's agency nurse--a growing challenge. PMID- 6903597 TI - Multiple sclerosis. PMID- 6903598 TI - Hospitals: what they represent. PMID- 6903599 TI - Continuing education. PMID- 6903600 TI - The beat goes on. PMID- 6903601 TI - Nursing management--cancer chemotherapy. PMID- 6903602 TI - [Current leukemia therapy and its trends]. PMID- 6903603 TI - [Early diagnosis and treatment of leukemia]. PMID- 6903604 TI - [Chemo- and immunotherapy and prognosis of leukemia--complications and their prevention]. PMID- 6903605 TI - [Early diagnosis of recurrence of acute leukemia in adults]. PMID- 6903606 TI - [Nursing care associated with current leukemia therapy]. PMID- 6903607 TI - [Treatment of infections associated with acute leukemia. Nursing care of the patient undergoing granulocyte infusion]. PMID- 6903608 TI - [Care and assistance of a leukemic child during drip infusion]. PMID- 6903609 TI - [Nursing assistance given to the mother of a child with acute leukemia]. PMID- 6903610 TI - [Conference: nursing of leukemic patients in a germ free ward]. PMID- 6903611 TI - [Physiopathology of "vertigo"]. PMID- 6903612 TI - [Vertigo and equilibrium]. PMID- 6903613 TI - [Clinical characteristics of vertigo and current, specialized treatment]. PMID- 6903614 TI - [Nursing of patients with vertigo--with special reference to Meniere's disease]. PMID- 6903615 TI - [Sequential changes in air-borne bacteria in a ward and a surgical room]. PMID- 6903616 TI - [Lymphography and nursing]. PMID- 6903617 TI - [Clinical course and nursing of patients with herpes zoster]. PMID- 6903618 TI - [Nursing experience with fatal hyperpyrexia associated with tranquilizers--a study on psychophysiologic nursing in a psychiatric department]. PMID- 6903619 TI - [Assistance in social rehabilitation of patients after an extended hospitalization at a psychiatric department]. PMID- 6903620 TI - [Various types of heart diseases]. PMID- 6903621 TI - [Nursing care of burns]. PMID- 6903622 TI - [Current definition of the aged]. PMID- 6903623 TI - [Careful selection of teaching materials and model format: a trial in a course for adult nursing. (1)]. PMID- 6903624 TI - [Report on personal teaching experiences. 4. A process in which students' comprehension takes place]. PMID- 6903625 TI - [Report on personal teaching experiences. 5. A conflict between kindness and professional attitude]. PMID- 6903626 TI - [Humanistic leadership in a pragmatic age]. PMID- 6903627 TI - [A survey on the image of the nurse]. PMID- 6903628 TI - [Teaching of nursing process with emphasis on individual differences - with special reference to clinical training in obstetrical nursing]. PMID- 6903629 TI - [Scenes with illness - 10. Room 527: people without families]. PMID- 6903630 TI - The disciplines of medicine and nursing. PMID- 6903631 TI - Out of controll: one aspect of infertility. AB - A perceived loss of control over many aspects of life often accompanies the problem of infertility. While most couples feel the effects of this lack of control in their lifestyle, relationship, and reproductive capacities, there are also some benfits inherent in giving up some control of the problem to outside sources. Nursing interventions are discussed which incorporate the concept of control into the plan of care for the infertile couple. PMID- 6903632 TI - Basics of breastfeeding. Part II: the anatomy and psychophysiology of lactation. AB - The major anatomical structures of the lactating breast are identified and related to the psychophysiologic mechanisms of lactation. Hand expression of breast milk is explained in a practical manner and some causes of lactation dysfunction are described. PMID- 6903633 TI - Nursing and regionalization of perinatal services. AB - In regional perinatal projects, which include emphasis on service coordination and education, nursing must be planned to coordinate with the general goals of regionalization that go beyond the limits of individual institutions. This approach was applied in one such program where the nursing departments were successfully united to develop nursing care standards. A multifaceted educational program, based on these standards and a survey of 200 nurses, is in operation. This experience suggests that it is possible to organize perinatal nursing care throughout regions as long as due consideration of hospital individuality and autonomy is extended. PMID- 6903634 TI - Recognizing fetal alcohol syndrome in the nursery. PMID- 6903635 TI - Nurse practitioner acceptance in private Ob/Gyn practice. AB - One of the ways to help meet consumer demands is by utilizing nurse practitioners in private Ob/Gyn practices. To determine consumer satisfaction with a nurse practitioner in one such practice, patients were asked to fill out a response sheet after their examination by the nurse practitioner. The 86 patients felt they received a good medical examination and would be willing to see the nurse practitioner on future visits. The physician and nurse practitioner found this change in delivery of health care to be a positive experience for both patient and professional. PMID- 6903636 TI - Maternal attitudes in prepared and unprepared cesarean deliveries. AB - Cesarean preparation classes were instituted in an Eastern hospital and are described here briefly. One hundred and forty-three prepared and unprepared women delivering vaginally and by cesarean during a six-week period at that hospital were tested with the Maternal Attitude to Pregnancy Instrumemt. Prepared cesarean women had a significantly greater desire for active participation in the delivery than women unprepared for cesarean delivery. Multiparous cesarean-delivery mothers with previous vaginal deliveries had a significantly more positive attitude than those who had never delivered vaginally. PMID- 6903637 TI - Culturally induced postpartum depression: a theoretical position. AB - A three-factor theory, based on an independently conducted survey of 49 primigravidas, is postulated to explain the potential that exists for cultural attitudes toward pregnancy to become precipitating agents in the postpartum depression syndrome. Changes in body proportions, public attitudes, and the social lives of expectant women are viewed primarily as negative experiences which result in a loss of self-esteem. A means of reducing cognitive dissonance by increasing interaction with those also pregnant is proposed. PMID- 6903638 TI - The new birth experience. PMID- 6903639 TI - The post-op gyn patient: questions and answers. PMID- 6903640 TI - [Confinement from the viewpoint of the midwife and her patient]. PMID- 6903641 TI - [A test at sea]. PMID- 6903642 TI - [A letter]. PMID- 6903643 TI - [The ability to stop smoking is our mutual concern]. PMID- 6903644 TI - [Social position of nurses in the modern history of nursing in Japan and its evaluation]. PMID- 6903645 TI - [Sexuality of the aged. (7)]. PMID- 6903646 TI - [Profile of a nurse: Ms. Yasuko Fujiwara - problems in nursing education and her future trip to Mexico as part of the exchange program]. PMID- 6903647 TI - [Topics in nursing - primary health care]. PMID- 6903648 TI - [Medical topics - contraceptive pills and hepatobiliary cancer]. PMID- 6903649 TI - [Medical topics - endotoxins]. PMID- 6903650 TI - [Discovery during hospitalization]. PMID- 6903652 TI - [ICN/WHO joint workshop on the "role of nursing in primary health care"]. PMID- 6903651 TI - [Opening remarks by the President at the General Assembly]. PMID- 6903653 TI - [Programmed learning: anxiety - perception and intervention]. PMID- 6903654 TI - [3 years' effort in promotion of labor conditions for nurses: observations at adoption of the recommendation on working conditions for nursing personnel]. PMID- 6903656 TI - [Nursing experiences in understanding of patients]. PMID- 6903655 TI - [Primary health care]. PMID- 6903657 TI - [On understanding and comprehension]. PMID- 6903659 TI - [Overview on continuing education in nursing in the 80's and the responsibility of the professional organizations. JNA Committee report]. PMID- 6903658 TI - [Significance of recognition of items not fully understood]. PMID- 6903660 TI - ["Understanding" in nursing. A discussion]. PMID- 6903661 TI - [Creative writing in nursing education - psychological process related to nursing expressed in verses]. PMID- 6903662 TI - [Analysis of nursing information at the transfer of patients. 2. Evaluation of the transfer method]. PMID- 6903664 TI - [Sexuality of the aged]. PMID- 6903663 TI - [Social position of nurses in the modern history of nursing in Japan and its evaluation]. PMID- 6903665 TI - [Profile of a nurse. Ms. Kazu Kawashima who is active in home nursing services]. PMID- 6903667 TI - [Medical topics: cholelithiasis and acute pancreatitis]. PMID- 6903666 TI - [Medical topics: ovarian cancer]. PMID- 6903668 TI - [Medical topics: prostaglandin]. PMID- 6903669 TI - [Suicide and attempted suicide. II. Understanding, recognizing and acting]. PMID- 6903670 TI - [Water as a source of infection]. PMID- 6903671 TI - [First aid in drowning]. PMID- 6903672 TI - [Current aspects in performance evaluation. To what extent is performance measurable in nursing?]. PMID- 6903673 TI - [Dying as an individual destiny. Theological and ethical reflections on the limits of aid to the dying]. PMID- 6903674 TI - [A bit of guidance: possibilities and limitations of hospital medicine from the ethical viewpoint]. PMID- 6903675 TI - Innovative nurses demonstrate expanded roles. PMID- 6903676 TI - Education for aging. AB - The increasing proportion of older adults within the population has two major implications for health education. First, provision of factual information relating to increasing longevity at optimal levels of wellness is likely to produce a new generation of older adults able to enjoy an improved quality of life during the later years. Second, self-esteem and positive emotional health can be enhanced through programs emphasizing positive attitudes regarding this stage of the life development cycle. Basic concepts and generalizations related to aging are presented to illustrate how aging content can be integrated within existing health curricula. As each of us ultimatley must develop a successful pattern of aging to enjoy older adulthood, the provision of a clearer understanding of the aging process is a responsibility that must be addressed within the arena of the schools. PMID- 6903677 TI - Psychosocial aspects of chronic illness in children. PMID- 6903678 TI - Is "natural" always healthy? PMID- 6903679 TI - Helping the child with cancer go back to school. PMID- 6903680 TI - Two promising measures of health education program outcomes and asthmatic children. AB - Two measures of health education program outcomes were administered to a group of 50 asthmatic children: the Child's Health Locus of Control Scale and the Piers Harris Children's Self Concept Scale. Interest centered on the reliabilities and discriminant validity of these instruments. Results showed high alpha reliabilities for both scales and a low, positive intercorrelation. Mean health locus of control and self-concept scores for this group were comparable to those of healthy children. These findings may be useful in designing and evaluating health education programs for children with asthma. PMID- 6903681 TI - Barriers to sex education. PMID- 6903683 TI - School health training for the practicing physician. PMID- 6903682 TI - Health education programs in New Jersey public schools. PMID- 6903684 TI - The role of the state school nurse consultant. PMID- 6903685 TI - Visual function: electrophysiological tests. PMID- 6903686 TI - Curriculum guides for nutrition education. PMID- 6903687 TI - Getting corporate funding for health education. PMID- 6903688 TI - Adolescence: psychological and social development. PMID- 6903689 TI - It's never too early for nutrition education. PMID- 6903690 TI - School nursing & dental referrals. PMID- 6903691 TI - Children's food preferences. PMID- 6903692 TI - Writing a health education curriculum guide from scratch. PMID- 6903693 TI - Most frequently cited health education articles, 1969-1977. PMID- 6903694 TI - Is your school prepared to handle emergency care? PMID- 6903695 TI - Ageism: need we discriminate? PMID- 6903696 TI - Nurses in service to their community. PMID- 6903697 TI - The use and transmission of audio-visual material in overseas schools of nursing and medicine. PMID- 6903698 TI - Some aspects of neurophysiological sciences at Royal Alexandra Hospital for Children. PMID- 6903699 TI - Community development principles. PMID- 6903701 TI - Performance of student nurses on clinical skills assessment test. PMID- 6903700 TI - Our birthday, by the second twin. PMID- 6903702 TI - Nurses graduating with diplomas of applied science: their attitudes toward their training and careers. PMID- 6903703 TI - Sensory psychology. PMID- 6903704 TI - A prisoner of neglect: 'I pray that I may die.'. PMID- 6903705 TI - New & changing technology: treating ulcers with a laser; an electronic device that puts a heart in the right place. PMID- 6903706 TI - Development of an item bank. PMID- 6903707 TI - Psychiatric hospitals treatment of schizophrenia and staff attitudes. PMID- 6903708 TI - Post basic education: a certificate course in emergency care nursing. PMID- 6903709 TI - Ureteric reimplantation: paediatric surgical study. PMID- 6903710 TI - Rehabilitation - a community setting and Dylan Thomas. PMID- 6903711 TI - Case history: experiences of a baby health sister. PMID- 6903712 TI - Progress report: hospitals rationalisation. PMID- 6903713 TI - Viewpoint: Year of the Child. PMID- 6903714 TI - When your child dies: the Compassionate Friends. PMID- 6903715 TI - Manpower utilisation and quality control. PMID- 6903716 TI - Asbestos hazard at Monson Developmental Center. PMID- 6903717 TI - An experience with the Kampuchean refugees. PMID- 6903718 TI - [Treatment of children with iron-deficiency anemia]. PMID- 6903719 TI - [Systemic blood diseases of hereditary origin]. PMID- 6903720 TI - [Typological traits in personality]. PMID- 6903721 TI - [Ophthalmic migraine]. PMID- 6903722 TI - [Electrical injuries to the eyes]. PMID- 6903723 TI - [Chronic tonsillitis]. PMID- 6903724 TI - [Clinical aspects and treatment of ichthyosis]. PMID- 6903725 TI - [Lichen ruber planus]. PMID- 6903726 TI - [Poikilodermatomyositis]. PMID- 6903727 TI - [Phytotherapy in dermatology]. PMID- 6903728 TI - [Rendering first aid and the treatment of lesions from poisonous marine animals]. PMID- 6903729 TI - [Treatment of rhinitis and rhinopharyngitis using a mixture of copper, Eucalyptus and tea]. PMID- 6903730 TI - [Work of the nurse in a venereology office]. PMID- 6903731 TI - [Rules for patients undergoing a course of treatment in physical therapy offices]. PMID- 6903732 TI - [Standardized control over student knowledge in carrying out final assignments]. PMID- 6903733 TI - [Method of planning preventive inoculations and the principles of estimating their effectiveness. II]. PMID- 6903734 TI - [Principles and methods of vaccination. III]. PMID- 6903735 TI - [Cerebral aneurysm in childhood]. PMID- 6903736 TI - [First aid in closed injuries to the chest cavity organs]. PMID- 6903737 TI - [New massage procedure applicable to bronchial asthma (methods and technic)]. PMID- 6903738 TI - [Emergency care in acute toothache]. PMID- 6903740 TI - [Therapeutic physical exercise in the overall treatment of bronchial asthma]. PMID- 6903739 TI - [Therapeutic physical exercise in endarteritis obliterans]. PMID- 6903741 TI - [Hidradenitis]. PMID- 6903742 TI - [Role of nurses in the development of the blood donor system]. PMID- 6903743 TI - [Role of paramedical personnel in realizing a complex of rehabilitative measures]. PMID- 6903744 TI - [Work of the nurse in the day-care hospital for mental patients]. PMID- 6903745 TI - [Nurse and patient social rehabilitation]. PMID- 6903746 TI - [Physiotherapy in the social rehabilitation of the mentally ill]. PMID- 6903747 TI - [Therapeutic physical exercise in the system of patient rehabilitative treatment]. PMID- 6903748 TI - [Work organization of the paramedical personnel in reflexotherapy offices]. PMID- 6903749 TI - [Importance of social living condition studies for the rehabilitation of the mentally ill]. PMID- 6903750 TI - [Ideological educational work in the collective]. PMID- 6903752 TI - [Scientific organization of work in performing polyclinic patient registration]. PMID- 6903751 TI - [Patients themselves register for a physician consultation]. PMID- 6903753 TI - [Work of offices for treating alcoholism patients in industrial, construction and agricultural enterprises]. PMID- 6903754 TI - [Changes in the organ of vision in collagen diseases]. PMID- 6903755 TI - [Work of a central sterilization department]. PMID- 6903757 TI - [Our traditions (from the work experience of a tutors' council]. PMID- 6903756 TI - [Nervous system lesion in brucellosis]. PMID- 6903758 TI - [Role of the tutorial system in the communist education of youth]. PMID- 6903759 TI - [Role of the nurses' council in maintaining sanitary, hygienic conditions in a therapeutic institution]. PMID- 6903761 TI - [Use of electrooculography in ophthalmology]. PMID- 6903762 TI - [Ethics and deontology for the intensive therapy ward nurse]. PMID- 6903760 TI - [Work experience of a coordinating methods center]. PMID- 6903763 TI - [Characteristrics of the deontological education of nurses in polyclinics]. PMID- 6903764 TI - [Fracture treatment by skeletal traction]. PMID- 6903765 TI - Who will serve the vulnerable populations? Human rights and health care for the aged. PMID- 6903766 TI - Equal pay for women: thoughtful strategies are developing. PMID- 6903767 TI - Preference for off-campus courses in a graduate nursing program. PMID- 6903768 TI - Nursing in Hong Kong: roadblocks to an expanded role? PMID- 6903769 TI - Today's family lifestyles: tomorrow's parents. PMID- 6903770 TI - Professional standards--mandatory issues for bargaining. PMID- 6903771 TI - Nursing students in the OR. PMID- 6903772 TI - Another hat, another uniform. PMID- 6903773 TI - Educating patients about their medication. PMID- 6903774 TI - Acetate vs. bicarbonate dialysis. PMID- 6903776 TI - Arrhythmias and the dialysis nurse. Some to be aware of--some to beware of. PMID- 6903775 TI - Acute tubular insufficiency: nursing impact on recovery. PMID- 6903777 TI - Psycho-social stressors impacting on adults on hemodialysis. PMID- 6903778 TI - You can prevent peritonitis. PMID- 6903780 TI - Femoral catheterization: the nurse's role. PMID- 6903779 TI - Peritoneal dialysis--a nursing update. 1. Physiological aspects and nursing responsibilities. PMID- 6903781 TI - Components of a successful home dialysis program. PMID- 6903782 TI - The evolution of medical uncertainty. AB - Modern developments of scientific medicine have uncovered and created uncertainties and risks that were previously not known or experienced; the stakes have become very much higher. The rise in public expectation, however, is paralleled by a lowered tolerance of uncertainty. Metaphors of "deliverance" and "disaster" abound in discussions of scientific discovery, reflecting differing conceptions and philosophies about errors and mistakes, and the role they play in the physical universe, the biosphere, and human affairs. These concerns highlight the difficulties and dilemmas of finding scientifically adequate, culturally appropriate, and socially effective ways of appraising and controlling risk. PMID- 6903783 TI - Representing consumer interests: imbalanced markets, health planning, and the HSAs. AB - The health planning legislation of 1974, establishing HSAs, represented an important attempt to break recurring patterns of decision making in public choices. One widely heralded strategy for controlling contemporary medical care- consumer involvement through accountability, representation, and participation- is flawed by failure to recognize that political markets are always imbalanced because of unequal interests and disproportionate resources. How can we represent broad, diffuse interests when all the incentives point to domination by a minority of intensely interested producers? Solutions favored at the local level may not best serve the entire nation; they cannot mirror the full spectrum of constituencies. Adjustment of mechanisms both internal to HSAs and external to them are suggested--yet, even so, their mandate reaches beyond possibility of accomplishment. PMID- 6903784 TI - Changing the balance of power in American medicine. AB - Representation and competition, as democratic and market strategies, have been of small consequence in producing significant improvement in medical care. Membership in an HMO is a greater source of consumer power than is representation in an HSA. Regulation and competition will continue to have limited--often ironic and incoherent--results in the absence of new institutional structures for reform. PMID- 6903785 TI - The problem of monopoly power in federal health policy. AB - Federal programs to regulate health care providers appear to have contradictory objectives, indicating ambivalence toward group power in American political philosophy. The conflict between monopoly-creating monopoly-destroying strategies is demonstrated through three attempts to integrate professional power into a democratic political system. PMID- 6903786 TI - Antitrust enforcement in the medical services industry: what does it all mean? AB - Before 1975, federal antitrust authorities neglected the health care sector, thereby allowing the entrenchment of many anticompetitive practices and institutions that seemed not only "natural," but also beneficial to the quality and professionalism of doctor-patient relations. While antitrust enforcement shares the usual physician preference for free enterprise, prosecutorial discretion is often feared as eroding professional discretion and even well intentioned reform. However, strengthened competition in the health services industry offers a way to bring some stability to health policy, and to resolve some of the conflicts between advocates of institutional status quo and enthusiasts for increased government regulatory power. PMID- 6903787 TI - Social science and health services research: contributions to public policy. AB - Public skepticism of the promised links between research and practical ends, and of the role of natural scientists as the ultimate judges of progress, is not new. After the unprecedented new social legislation and related research of the 1960s, social scientists today are being questioned about their contribution to improved public policy. Government interventions in the health services industry created new needs for information and knowledge, and at the same time altered the institutions and mechanisms through which relevant research is conducted and used. Social scientists and public officials will have to act in concert in response to new policy and research environments. PMID- 6903788 TI - Observations on health services research and health policy analysis. AB - The importance of mutual communication between researchers and policy makers cannot be overestimated. Although economists are presumed to have an advantage, more interdisciplinary health services research is needed. The case for government support of research and use of its findings is not based solely on government spending for health care. The interests of the federal programs are not well served by a declining access to data or by ambiguous distinctions between research and policy analysis. PMID- 6903789 TI - Evaluating medical technology in the context of a fiscal crisis: the case of New Zealand. AB - Planning for health services in New Zealand, and the implications of increasing use of high technology, fail to take account of the mounting crisis in the country's economy. Social policy that ignores structural problems in the economy or the system of medical care is unrealistic. A strategy is advanced to determine what resources are likely to be available, and how they can be allocated to ensure value for money. The situation is not unique to New Zealand. PMID- 6903790 TI - Public health and public wealth: social costs as a basis for restrictive policies. AB - Historically the most important rationale for coercive public health measures has been the prevention of disease and harm to others. As noncommunicable diseases, induced by personal habits, account for higher rates of death and disability, governmental restrictions on individuals are being based on a new argument- social costs. Indirect monetary effects are substituted for direct health effects. But since we lack precise measurements of net costs, the risks of coercion should be approached cautiously. PMID- 6903791 TI - The National Health Service Corps: rapid growth and uncertain future. AB - From inauspicious origins in laudable, but vague, legislation and diffident--even disorganized--implementation, the NHSC has evolved into a major federal program for delivering health care to underserved areas. Tying together the financing of medical education and the delivery of health services for the first time could enable responsiveness to both qualitative and quantitative changes in medical care. But competing demands, within the program and its administration, and in the communities to be served, have made evaluation of the NHSC effort and impact difficult, but all the more necessary for future planning. PMID- 6903792 TI - Marketing principles and the future of preventive health care. AB - Whether preventive programs are advanced as complementary to therapy or as partial substitutes to lower costs, public resistance makes the cost effectiveness of these programs questionable. "Marketing" may be helpful in differentiating among the nature of products, services, and ideas of prevention, on the one hand, and heterogeneous consumer needs, attitudes, and responsibilities on the other. Making policy for marketing will involve new strategies and use of leverage: the "message' is not the only medium. PMID- 6903793 TI - Social and economic attitudes shaping American health policy. AB - The Health Clark Lectures (University of London) explore the development of American health care policy in a social and economic context; the probability of transatlantic relevance is substantial. I. American Health Care: Selected Policy Issues. The U.S. economy is beset with difficulties, and social policy bends to these realities and to perceptions of them. In the climate of growing neoconservatism, efforts to develop a coherent and cohesive national health policy are discontinuous and even inconsistent. II. Efficiency and Equity in Medicine: The Role of the Economist. The critical issue for economic policy is the amount spent for health care in society; for social policy it is the way that amount is shared. Certainly, there is an interplay between the two, but we must be wary of finding common ground in economic-investment and benefit-cost approaches. Striving for equity offers the best strategy to attain efficiency. PMID- 6903794 TI - Toward an epidemiology of work disability. AB - The indirect cost of illness due to lost wages exceeds the cost of medical services by a large margin. Social characteristics of persons with physical impairment are more important than the characteristics of their medical condition in predicting whether disability will lead to work loss. Public policy toward disability currently emphasizes the "human capital" with which persons with impairments confront the labor market; this study suggests a new emphasis on social characteristics of the workplace. PMID- 6903795 TI - Models of man and models of policy: reflections of "Exit, Voice, and Loyalty" ten years later. AB - The challenge of health care policy is how to combine sensitivity to both consumer preferences (the economic model) and citizen wishes (the political model): what either wants the other may wish to deny him. Competing economic (exit) and political (voice) activities in response to deterioration in the quality of a service, however, may be an inadequate framework to encompass discontent with the complex mix of types of services offered. The "political market" in which decisions about health care are made is suggested for further exploration. PMID- 6903796 TI - Repeated hospitalization for the same disease: a multiplier of national health costs. AB - In five typical hospitals, and a specialized treatment center, more than half of all patients--and 60 percent of all costs--were attributable to repeated admissions for the same disease. The fiscal and clinical nature of repeated hospitalization suggests changes for national health policy. These will require more sensitive identification of patients "at risk" of recidivism, and insurance mechanisms that relate more rationally and equitably to long-term needs. PMID- 6903797 TI - Assessing the evidence on HMO performance. AB - HMOs contract to provide physician and hospital services to enrolled populations in return for fixed periodic payments. Total costs for HMO members are shown to be lower than for those enrolled in conventional insurance plans. But the explanation for this and related differences cannot be attributed solely to matters of efficiency, quality, or even consumer self-selection or physician satisfaction. Although public policy assumes that HMOs will encourage beneficial competitive responses by traditional health care providers, too little is known to predict the nature and extent of such probabilities. PMID- 6903798 TI - Health status and health care use by type of private health coverage. AB - There is considerable speculation on the causes of the frequently observed lower rates of hospital use by group practice--or HMO--members than by persons covered by other health care arrangements. It is often asserted that HMO enrollees are a self-selected healthier population, or that their use of hospitals is not fully recorded. A major study in California of the actual health and use of hospitals by a representative sample of persons under age 65 showed these assertions to be unfounded. PMID- 6903799 TI - The federal government as venture capitalist: how does it fare? AB - The federal government's interest in promoting the development of HMOs is a unique experiment in venture capitalism. Under the beleaguered administration of the Office of Health Maintenance Organizations, the conflicting goals and procedures of government and private business have not been easily reconciled. Within a department (HHS) that tilts to regulatory approaches, OHMO has made some notable progress as an outpost of marketplace solutions to the problems of production, distribution, and financing of health care. PMID- 6903800 TI - Perspectives on improving nursing's public image. PMID- 6903801 TI - Supply and demand for registered nurses: some observations on the current picture and prospects to 1985. Part 1. PMID- 6903802 TI - Nursing: a professional practice discipline in Academia. PMID- 6903803 TI - Who determines health manpower policy? PMID- 6903804 TI - 17 large hospitals surveyed: trends revealed. PMID- 6903805 TI - Toward a more definitive understanding of the nurse's role. PMID- 6903806 TI - Carter Administration foresees an era of cautious expansion of health care programs. Republicans look toward greater private sector and consumer involvement in health. PMID- 6903807 TI - Caring: a central focus of nursing and health care services. PMID- 6903808 TI - Primary nursing - the adoption of nursing care modality. PMID- 6903809 TI - Cost and quality: primary and team nursing compared. PMID- 6903810 TI - Measuring a nursing services department's effectiveness. Designing the assessment instrument. PMID- 6903811 TI - Recognizing and caring for the patient with Legionnaire's disease. PMID- 6903812 TI - Career guide: if you're moving into management... PMID- 6903813 TI - Sharing: what Danny didn't know. PMID- 6903814 TI - Your fingers on the pulse. Evaluating what you feel. PMID- 6903815 TI - Solving the very big problems of the morbidly obese. PMID- 6903816 TI - Nursing grand rounds: diabetes in pregnancy: special care for a special case. PMID- 6903817 TI - Theophylline. Know how to handle this potent bronchodilator. PMID- 6903818 TI - Compartmental syndrome. PMID- 6903819 TI - Primary nursing. What's so exciting about it? PMID- 6903820 TI - How to relieve your patients' pain fast and effectively ... with oral analgesics. PMID- 6903821 TI - A checklist for better discharge planning. PMID- 6903823 TI - Caring for the catheter carefully ... before, during, and after peritoneal dialysis. PMID- 6903822 TI - The part-time question and the hospital's answer. Part 2. PMID- 6903824 TI - Test your knowledge of medical nursing. PMID- 6903825 TI - Difficult patients. Cal wanted to take charge. PMID- 6903826 TI - Beliefs and behaviour: introduction. PMID- 6903827 TI - Nurses are individuals too. PMID- 6903828 TI - Understanding patients' beliefs. PMID- 6903829 TI - Practical care of Asian patients. PMID- 6903830 TI - Religion as a way of life. PMID- 6903831 TI - Beliefs and behavior: body image. PMID- 6903832 TI - Pictures in nursing: mastectomy and body image. PMID- 6903833 TI - The hospital chaplain. PMID- 6903834 TI - Birth control. PMID- 6903835 TI - Family planning and immigrants. PMID- 6903837 TI - Health education. PMID- 6903836 TI - Careers in nursing: VD clinics. PMID- 6903838 TI - Some new prospects in management development. PMID- 6903839 TI - Pick your problem! Random reflections by a community physician. PMID- 6903840 TI - Cheaper in the community? PMID- 6903841 TI - Continuing education: 2. A change of direction. PMID- 6903843 TI - Career advancement programs: careers in nursing practice. PMID- 6903842 TI - An unattainable ideal. PMID- 6903844 TI - Are you a match for primary nursing? PMID- 6903845 TI - Career opportunities in critical care nursing. PMID- 6903847 TI - CE roundup: mandatory CE. The status today. PMID- 6903846 TI - Focusing on continuing education in nursing. Correspondence instruction: one way to learn. PMID- 6903848 TI - Selecting a job that satisfies. PMID- 6903849 TI - The Health Management Cooperative of California. Multiple choice: a cooperative approach to nursing careers. PMID- 6903850 TI - More matches for primary nursing. PMID- 6903851 TI - Career advancement programs: a model to identify levels of professional practice. PMID- 6903853 TI - CE roundup. PMID- 6903852 TI - Diagnosing stress in your nursing world: a home-study course good for three contact hours of CE credit. PMID- 6903854 TI - Why practice in a small town? PMID- 6903855 TI - The nursing shortage: current trends in recruitment and retention. A solution to the nursing shortage. PMID- 6903856 TI - The nursing shortage: current trends in recruitment and retention. Has recruitment outgrown recruiters? PMID- 6903857 TI - The nursing shortage: current trends in recruitment and retention. Recruiting and retaining nurses. PMID- 6903858 TI - Critical issues. PMID- 6903859 TI - The NHS and the psychiatrically ill worker. PMID- 6903860 TI - Safety: whose responsibility?--2. PMID- 6903861 TI - Clockwise: a guide to working flexible hours. PMID- 6903862 TI - Fire, mist and vapours--2. PMID- 6903863 TI - Safety: planning for emergencies. PMID- 6903864 TI - A meeting of minds: Avon's OH society. PMID- 6903865 TI - An alternative to the patient's Bill of Rights. PMID- 6903866 TI - [Kinin system component study in viral hepatitis in children]. PMID- 6903867 TI - Starting a private practice of psychotherapy. PMID- 6903868 TI - Self-disclosure: implications for mental health. PMID- 6903869 TI - Should there be a national organization of directors of graduate programs in psychiatric mental health nursing? PMID- 6903870 TI - Should there be a national organization of graduate programs in psychiatric mental health nursing? PMID- 6903871 TI - The psychiatric nurse--accountable? to whom? for what? PMID- 6903873 TI - This is the National League for Nursing. PMID- 6903872 TI - Supply and demand for registered nurses: some observations on the current picture and prospects to 1985. Part 2. PMID- 6903874 TI - Community health nursing: education and practice. PMID- 6903875 TI - Perspectives of community health nursing practice. PMID- 6903876 TI - Perspectives of community health nursing education. PMID- 6903877 TI - Competencies for practice of community health nursing. PMID- 6903878 TI - Application of theories, models and constructs for the practice of community health nursing. PMID- 6903880 TI - Factors influencing accountability in nursing education. PMID- 6903879 TI - Quality assurance in a home health agency. PMID- 6903881 TI - Factors that influence accountability in community health nursing education and practice. PMID- 6903882 TI - Community health nursing--our challenge. PMID- 6903883 TI - Nucleotide sequence of Scenedesmus obliquus cytoplasmic initiator tRNA. AB - The cytoplasmic initiator tRNA from the green alga Scenedesmus obliquus has been purified and its sequence shown to be p A G C U G A G-U m G m G C G C A G D G G A A G C G psi m G A psi G G G C U C A U t A A--C C C A U A G m G D m C A C A G G A U C G m A A A C C U Gm U C U C A--G C U A C C A-O H. The sequence has been deduced and confirmed using several different P-post labelling techniques. The sequence is similar to those of other eukaryotic cytoplasmic initiator tRNAs and it has the sequence G A U C in place of the usual G T psi C. Although it resembles lower eukaryotic species in having a U preceding the anticodon and a modified G in the T psi C stem, in overall homology it is closer to the higher eukaryotic than to the fungal initiator tRNAs. PMID- 6903884 TI - The nucleotide sequence of a major species of leucine tRNA from bovine liver. AB - Through the use of a variety of post-labeling techniques, the nucleotide sequence of a major species of leucine tRNA from bovine liver was determined to be pG-G-U A-G-C-G-U-G-m-G-C-ac-C-G-A-G-C-G-G-D-C-psi-A-A-G-G-C-m-G-C-U-G-G-A-psim- U-I-A-G m-G-C-psi-C-C-A-G-U-C-psi-C-psi-U-C-G-G-G-G-G-m-C-G-U-G-G-G-T-psi-C-G-m -A-A-U-C C-C-A-C-C-G-C-U-G-C-C-A-C-C-AOH. A comparison of known sequences of leucine tRNAs shows a consistent set of features which clearly distinguish prokaryotic and eukaryotic leucine tRNAs from each other. PMID- 6903885 TI - Power and interest groups: a study of ANA and AMA. PMID- 6903886 TI - Graduate education for the anesthesia nurse practitioner. PMID- 6903887 TI - Changing patterns in school health and school nursing. PMID- 6903888 TI - A student leadership experience for the experienced RN. PMID- 6903889 TI - Does the nurse practitioner involve the patient in his care. PMID- 6903890 TI - Joint endeavors: the way to bring service and education together. PMID- 6903891 TI - The strengths and weaknesses in nursing service administration. PMID- 6903892 TI - Nursing administrators' assessment of nursing education. PMID- 6903893 TI - Television talk shows: an untapped resource for nursing. PMID- 6903894 TI - Conflict resolution and the communication myth. PMID- 6903895 TI - Alumni involvement in nursing research development. PMID- 6903896 TI - All systems go--but slowly. PMID- 6903897 TI - Wielding Occam's razor. PMID- 6903899 TI - Use of automobile restraining devices for infants. AB - Use of crash-tested and approved restraining devices for infants was studied in relationship to parents' locus of control, knowledge scores, and demographic data. Of 66 mothers who provided complete data, 19 (29 percent) owned and made proper use of the devices. Thirty-four mothers (52 percent) owned devices but did not use them properly. PMID- 6903898 TI - Engagement-involvement and blood pressure change: a methodological inquiry. AB - In a study that examined further Singer's model of engagement-involvement in a community nursing setting, 31 black inner-city women conversed informally with a nurse while their blood pressure was monitored at two-minute intervals using a Hoffman-LaRoche Arteriosonde. Type A (coronary-prone) and hypertensive subjects were judged to not display greater engagement than type B and normotensive subjects, respectively. Within-subject correlations between observers' ratings of engagement and blood pressure showed substantial differences across subjects. Nevertheless, for correlations based on engagement judgments corresponding to the minute immediately preceding the blood pressure determination the mean within subject values ranged from .14 to .32 (mean = .20) and were all significantly different from zero. Attention is directed to the need for refining the criteria used for judging engagement and to identifying patients for whom increased engagement may invalidate blood pressure measurements in a clinical setting. PMID- 6903900 TI - A hard hand-positioning device to decrease wrist and finger hypertonicity: a sensorimotor approach for the patient with nonprogressive brain damage. AB - To investigate whether a hand-positioning device placed in the palm of a patient with nonprogressive brain damage will decrease hypertonicity of the flexor muscles of the hand through proprioreceptive sensory input to the alpha-gamma coactivation loop, a hard cone was placed in the affected hand of 11 subjects who had sustained cerebrovascular accidents and had flexor hypertonicity of the upper extremity. Measurements of hypertonicity and functionality were made weekly for four weeks. All subjects experienced a significant decrease in flexor hypertonicity. Only slight changes were observed in functionality. PMID- 6903901 TI - Attitude change as a motivational factor in producing behavior change related to implementing primary nursing. AB - This study examined the relationship between nurses' improved attitudes toward the feasibility of primary nursing within the Veterans Administration setting and resultant behaviors directed at implementing primary nursing. Festinger's cognitive dissonance theory served as an explanatory model for observed outcomes. Improved attitudes motivated participants to engage in predicted behaviors. Findings implied that effective training is maximized in situations in which correspondence exists between the source of the behavioral deficiency and educational activities designed to remedy the deficiency. PMID- 6903902 TI - Sex-role identity and image of nursing of females at two levels of baccalaureate nursing education. AB - Ninety-two female nursing students, 56 at entry (ENTL) to and 36 at exit (EXTL) from the baccalaureate program, participated in an investigation of the relationship between sex-role identity and image of nursing. Bem's Sex Role Inventory, which allows subjects to receive both masculinity and femininity scores, was used to categorize subjects as masculine, androgynous, feminine, or undifferentiated. Frank's Image of Nursing Questionnaire was used to evaluate subjects' image of nursing. Study purposes were to: compare the sex-role identity of nursing students and general college females, compare the image of nursing held by nursing students with the image advanced by the profession, determine the relationship between sex-role categorization and image of nursing, and determine the relationship between level of endorsement of masculine and feminine characteristics and image of nursing. Analyses indicated: a significant (p < .05) difference in sex-role identity based on categorization between the total nurse sample and general college females, EXTL students endorsed more masculine characteristics than ENTL students (p < .003), EXTL students endorsed more feminine characteristics than general college females (p < .001), ENTL and EXTL students and Frank's judges held significantly different images of nursing (p < .01 for all comparisons), and significant correlations between the image of nursing and level of endorsement of masculine characteristics, not masculine role identity, for EXTL (p < .002) and total nurse (p < .001) samples. PMID- 6903903 TI - Changing breast self-examination behavior. AB - Breast self-examination instruction was presented to 130 women. Four instructional methods used were: modeling alone, modeling plus guided practice, modeling plus self-monitoring, and modeling plus peer support. Follow-up data were collected at three- and six-month intervals. Data analyses revealed that, although the study population as a whole made statistically significant changes in breast self-examination behavior, no statistically significant outcomes were related to the dependent variables of frequency and knowledge of self-examination and confidence in ability to detect breast abnormalities between subjects in the modeling alone method--which served as the control--and subjects in the other three instructional methods. PMID- 6903904 TI - Paternal attachment behavior as related to presence at delivery and preparenthood classes: a pilot study. AB - This pilot study explored father-infant attachment and its relationship to preparenthood classes, presence at delivery, and infant state. The sample consisted of 48 fathers and their infants who were observed in the mother's hospital room between 12 and 72 hours after delivery. The fathers were divided into three groups: those who took classes and were present at delivery, those who were present at delivery but did not take classes, and those who neither took classes nor were present at delivery. Fathers who were present at delivery demonstrated more social attachment behavior than fathers who were not present. Also, presence at delivery was significant in regard to total attachment scores. Sleeping infants elicited significantly less attachment behavior from fathers. Preparenthood classes were not significant in regard to fathers' attachment behavior. Results of this study support the theory of a sensitive period shortly after birth for the development of the parental-infant bond for fathers as well as mothers, and demonstrates, indirectly, that alert, awake infants may elicit certain attachment behaviors from fathers. PMID- 6903905 TI - Mechanisms responsible for the sustained fall in arterial oxygen tension after endotracheal suctioning in dogs. AB - Because a sustained fall in arterial oxygen tension (PaO2) was observed after endotracheal suctioning in previous studies on anesthetized dogs and in humans, this study was designed to investigate the nature of the fall, its duration, and its response to several challenges. Experiments were performed at weekly intervals using three anesthetized dogs. Each dog was subjected to five experiments. In spontaneously breathing dogs, the duration of the sustained fall after suctioning or after suction catheter insertion without application of suction pressure persisted through 15 minutes. At 30 minutes afterwards, PaO2 had partially or completely returned to control levels. One hyperinflation breath given after suctioning did not produce a lasting reversal of the sustained fall, and pretreatment with isoproterenol mist inhalations failed to prevent the sustained fall. In dogs which were mechanically ventilated both before and after suctioning or catheter insertion without application of suction pressure, three hyperinflations before suctioning or pretreatment with isoproterenol failed to prevent the sustained fall. The data supported the hypothesis that a reflex mechanism, initiated by mechanical stimulation of the airways, was responsible for the sustained fall in PaO2 observed. PMID- 6903906 TI - Effect of teaching on primiparas' perceptions of their newborn. AB - To determine if a relationship exists between structured, informative in-home teaching concerning infant behavior and primiparous mothers' perceptions of their newborn, 30 primiparas completed Broussard's Neonatal Perception Inventories I and II. The sample--30 women between the ages of 18 and 30 who had had no chronic disorders and had experienced normal pregnancy, labor, delivery, and postpartal course--was deliberately selected from a 489-bed community teaching hospital; 15 women were assigned randomly to a control group and 15 to an experimental group. All participants completed NPI I on their first or second postpartum day. Experimental participants received structured, informative teaching concerning infant behavior two to four days after discharge. All subjects were again visited at one month to complete NPI II. Data were analyzed by t test; significance was set at p = .05. No significant difference was found between the groups in NPI I perceptions. On NPI II a significantly positive change in perception was found for the experimental group, but not for the control group. PMID- 6903907 TI - Three-minute time interval when using an oral mercury-in-glass thermometer with or without J-temp sheaths. PMID- 6903909 TI - Safety first. PMID- 6903908 TI - An exploratory study of body image dimensionality. PMID- 6903910 TI - Effect of restricted mobility and dominance on perceived duration. AB - Perceived duration has been found to decrease with decreased cadence and with increased muscular effort. In this study, 64 volunteer college-student subjects who walked a circular track at a preferred tempo produced temporal judgments significantly longer when either the right knee and ankle or the left knee and ankle were restricted, compared to their production estimates when they walked without restriction. No difference in production estimates was found when the effect of restriction of one leg was compared with that of the other. Decreased perceived duration, thought to result from a combination of decreased cadence and increased muscular effort necessitated by the restriction of mobility, may be a mechanism for preserving system integrity in those whose mobility is restricted. PMID- 6903911 TI - Movement therapy with the aged. AB - This study examined effect of participation in a movement therapy group on morale and self-esteem in a population of institutionalized aged persons. Control group subjects participated in the usual treatment program at the nursing home, and experimental group subjects participated in a series of movement therapy sessions. Scores on morale and self-esteem scales were used to compare differences between the groups. Movement therapy group members demonstrated greater improvement in total morale and attitudes toward their own aging. Findings from the study contribute to the body of knowledge of nursing science as well as to gerontological theory development by further defining types of activities which are compatible with successful aging and by providing empirical support for specific nursing interventions. PMID- 6903912 TI - A psychosocial screening tool for ambulatory health care clients: a pilot study of validity. AB - This study tested the concurrent validity of a psychosocial screening tool, the Assessment of Life Conditions Scale (ALC), a brief checklist developed at Kaiser Permanente Health Maintenance Organization. It was found to be a significant predictor of a client's score on two longer valid and reliable psychosocial screening tools, the Social Readjustment Rating Scale and the Heimler Scale of Social Functioning. Clients' ALC scores were significantly correlated with their perception of their current and usual health status. Their ALC score was also associated with their perception of how they felt a nurse could be most helpful to them during their clinic visit. This brief screening tool has potential usefulness for guiding mental health referrals for ambulatory health care clients and for planning nursing care. PMID- 6903913 TI - Patients' and spouses' causal explanations of a myocardial infarction. AB - This study examined lay explanations of an illness episode, myocardial infarction, at acute and convalescent phases of illness. Data were collected by interviews, using a structured questionnaire during the acute phase of illness (in hospital) and convalescent phase (at home) after discharge, from 50 first time MI patients and 50 spouses or significant others. Tension (at work, in the home situation, and in general) was the most frequent cause given for the heart attack by both patients and spouses at both phases. Half the patients and half the spouses changed their mind regarding the cause of the heart attack between the acute and the convalescent phases. Further, over 50 percent of the patient/spouse pairs disagreed regarding the cause of illness at both phases. A high percentage of patients changed their smoking, diet, and exercise behavior, even when they did not list these factors as causes of the heart attack. Findings also suggested spouses should be included in discharge planning and special problems which spouses may face after patients' discharge should be addressed. PMID- 6903914 TI - Relationship of sodium bicarbonate to intraventricular hemorrhage in premature infants with respiratory distress syndrome. AB - It has been suggested that hypertonic loads of saline built up in the administration of sodium bicarbonate to correct acidosis in infants with respiratory distress syndrome (IRDS) can precipitate intraventricular hemorrhage (IVH). Therefore, from medical records we noted the daily intake of sodium of 36 babies with IRDS who were on mechanical respirators. Eighteen of the infants developed IVH, and for these infants total sodium intake 24 hours prior to IVH was also recorded. The mean was 5.83 +/- 4.22 mEq/kg per day, a dose substantially less than the recommended limit of 8 mEq/kg per day. The difference between means was not significant (p = .071), but the variance was significant (p = .016). The results indicated that the total sodium dose, particularly that taken in during the sodium bicarbonate administration, did not regularly contribute to the development of IVH, when given under controlled conditions, that is, conservative doses, dilution, and slow injection to minimize the hypertonic load. PMID- 6903915 TI - Responses to life events as predictors of suicidal behavior. AB - This study, built on Jacobs' conceptual work, considered the interaction of a complex of predictor variables (hopelessness; locus of control; preference for inclusion, control, and affection; and stress from life events) in relation to the degree of suicide intent. Although the multiple regression equation computed for the combination of variables was significantly related to the criterion variable, suicide intent, hopelessness and preference for affection were the only major variables that contributed a significant amount of variance. Hopelessness, however, was the only variable that significantly related to suicide intent when considered outside the context of the multiple regression equation. In addition, the correlations between locus of control and hopelessness, as well as preference for affection and hopelessness, were significant and appeared to account for different variance than accounted for by the correlation of hopelessness and suicide intent. PMID- 6903916 TI - Dropouts from nursing education: path analysis of a national sample. AB - Path analysis was used to test a theoretical model of college nursing student dropouts. Multiple regression was used to assess the relative importance of the predictor variables. Students' self-reported reasons for dropping out were studied by contingency and correlational analyses to determine the relationship between these reasons and individual difference variables. Factor analysis was used to develop scales to measure the variables of locus of control, self-esteem, social integration, and institutional commitment. The sample of students was drawn from the National Longitudinal Study of the High School Class of 1972. Included in the sample were students entering two- and four-year nursing programs full-time in the fall of 1972. These two groups of students were found to be significantly different in measures of cognitive ability and in aspirations for further education. Approximately 27 percent of the two-year and 41 percent of the four-year students withdrew from their nursing programs during this study. Reasons for withdrawal most frequently cited by both groups related to losing interest in nursing and becoming interested in other fields of study. Educational aspirations had the strongest direct effect on persistence in nursing for two year students; for four-year students, academic ability was the most powerful predictor of persistence. PMID- 6903917 TI - Values of baccalaureate nursing students in secular and religious schools. AB - This study examined if and how values held by baccalaureate nursing students in secular and religious schools changed during their school experience. The Rokeach Value Survey was used to measure and assess respondents' hierarchical arrangement of two kinds of values, instrumental and terminal. Two-way analysis of variance was done on each value to ascertain difference by class level or school orientation. Significant differences were found for 25 of the 36 values when the students were compared for school orientation, but for only 17 or the 36 values when freshmen and seniors were compared. PMID- 6903918 TI - Factors influencing adolescents' perceptions of life change events. PMID- 6903919 TI - An investigation of nursing student self-concept levels: a pilot survey. PMID- 6903920 TI - Rubella on a university campus: an evaluation of case immunity histories. PMID- 6903921 TI - Systems and signs. The cardiovascular system-5. PMID- 6903922 TI - Management of violent patients. PMID- 6903923 TI - Psychiatric nursing for the eighties: 'into the arms of the big wide world'. PMID- 6903924 TI - Nitty Norahs--Cinderellas no more. School nurses want national training. PMID- 6903925 TI - An on-going polyphonic interaction. PMID- 6903926 TI - Nursing in an inner city area--Glasgow. PMID- 6903927 TI - Recruitment--3. The work of a nurse recruitment officer, careers adviser. PMID- 6903928 TI - Postoperative progress in a day-stay ward. PMID- 6903929 TI - Turncoat. Profundities over the bedpans. PMID- 6903930 TI - Nurse, are you there? PMID- 6903931 TI - Stop the world...I want to get off. PMID- 6903932 TI - Forty years on. Interview by Laura Swaffield. PMID- 6903934 TI - Motor neurone disease. PMID- 6903933 TI - Listening to patients. PMID- 6903935 TI - A district hospital disinfection unit. PMID- 6903936 TI - Recruitment--4. The work of a nursing careers adviser. A personal account of one approach to careers advice. PMID- 6903937 TI - Broadening horizons. A cross-cultural clinical experience. PMID- 6903938 TI - Organisation of activity periods for profoundly mentally handicapped young adults. PMID- 6903939 TI - Nursing care at a hospice. PMID- 6903940 TI - Robbie: a tale of rehabilitation? PMID- 6903941 TI - Theatre nursing supplement. An assessment of postoperative pain. PMID- 6903942 TI - Theatre nursing supplement. A wound infection explored. PMID- 6903943 TI - Theatre nursing supplement. Only a pair of eyes? PMID- 6903944 TI - A world-wide commitment. PMID- 6903945 TI - Stressing the point. PMID- 6903946 TI - Nursing care study: total pancreatectomy and splenectomy for a patient with chronic pancreatitis. PMID- 6903947 TI - The effect of an antibiotic spray on umbilical cord separation times. PMID- 6903948 TI - Music in hospitals. PMID- 6903949 TI - Recruitment--5. Looking for tomorrow's nurses. PMID- 6903950 TI - Recruitment--5. The role of an advertising agency in the recruitment exercise. PMID- 6903951 TI - The dependence of elderly people in residential homes. PMID- 6903952 TI - Making practice perfect? PMID- 6903954 TI - Much ado about agency nursing. PMID- 6903953 TI - Mentally handicapped children get homesick too. PMID- 6903955 TI - Suffer little children. PMID- 6903956 TI - Nursing care study: right lower lobectomy for bronchiectasis. PMID- 6903957 TI - Mr Smith's total laryngectomy. PMID- 6903959 TI - The changing nature of health education. PMID- 6903958 TI - Psychosocial problems of patients on renal dialysis. PMID- 6903960 TI - Recruitment--6. Where can I get help? PMID- 6903961 TI - The expected occupational satisfactions of student nurses. PMID- 6903962 TI - Hospitals should do the sick no harm. 10. Hospital acquired bacteraemia. PMID- 6903963 TI - Face to face with Europe. PMID- 6903964 TI - Barely managing? PMID- 6903965 TI - Research at work. PMID- 6903966 TI - A case for counselling. PMID- 6903967 TI - Marian Morgan. A new style president for the Rcn. Interview by Laurence Dopson. PMID- 6903968 TI - Community care study: a 'little' boy. PMID- 6903970 TI - Prescribed medicines in a residential home for the elderly. PMID- 6903969 TI - Revision arthroplasty of the hip. Some current methods for reducing failure in this branch of surgery. PMID- 6903971 TI - Recruitment. 7. A clearing house for entry to nurse training. PMID- 6903972 TI - What's in a game? PMID- 6903973 TI - National Association of Theatre Nurses: Lancashire lass. Interview by Tamara Ross. PMID- 6903974 TI - National Association of Theatre Nurses: the good and the bad. PMID- 6903975 TI - National Association of Theatre Nurses: small beginnings. PMID- 6903976 TI - National Association of Theatre Nurses: keep it clean! PMID- 6903977 TI - National Association of Theatre Nurses: correcting a 'list to port'. PMID- 6903979 TI - One nurse's week. PMID- 6903978 TI - How do you circumcise a whale? PMID- 6903980 TI - Profile - Eirlys Rees: the not so retiring President.. Interview by Nonnie Blackford. PMID- 6903981 TI - Law and the nurse: rule of law. PMID- 6903982 TI - Industrial relations: striking point. PMID- 6903983 TI - Hypertension. 2. The science of detection. PMID- 6903984 TI - Nursing care study.--Anorexia nervosa: a daunting prospect. PMID- 6903985 TI - The state of things to come? PMID- 6903986 TI - Clues to a leading question. PMID- 6903987 TI - Orthopaedics--cause unknown. PMID- 6903988 TI - Industrial relations. 2. A commitment to trust. PMID- 6903989 TI - Ward sister. Keeping watch on a vital link. PMID- 6903991 TI - Hypertension. 3. Keeping the pressure in check. PMID- 6903990 TI - One day at a time. PMID- 6903992 TI - International cancer nursing conference. 1. Nursing intervention during chemotherapy. PMID- 6903993 TI - Psychiatric care. On target with staff and patients. PMID- 6903994 TI - Microbiology. Defences up! PMID- 6903995 TI - Hypothermia. 1. Let the Christmas spirit live on. PMID- 6903996 TI - Myocardial infarction. A pain in the night. PMID- 6903997 TI - Home is where it's at. PMID- 6903998 TI - Pride of place. PMID- 6903999 TI - Orthopaedics. 2. Telling them apart. PMID- 6904000 TI - International conference on cancer nursing. 2. 'Let's face it.'. PMID- 6904001 TI - Everyone's favourite nurse. Interview by Tamara Ross. PMID- 6904002 TI - Burns--a continuing battle. PMID- 6904003 TI - Hypothermia. 2. The invisible baby killer. PMID- 6904004 TI - Planning--zero growth. PMID- 6904005 TI - Retarded growth in children. PMID- 6904006 TI - Entamoeba histolytica. PMID- 6904007 TI - Neonatal surgery--a flight for life. PMID- 6904008 TI - Gifted children. PMID- 6904009 TI - Struggling through days and nights with a hyperactive child. PMID- 6904011 TI - Health visitors. A little help goes a long way. PMID- 6904010 TI - Health visitors. The kiwi who came to Cable Street. Interview by Mark Allen. PMID- 6904012 TI - Health visitors. A team approach. PMID- 6904013 TI - Mind that child! PMID- 6904014 TI - A new lesson for school nurses. PMID- 6904015 TI - Teamwork--triumph or disaster? PMID- 6904016 TI - Putting the pressure on blood. PMID- 6904018 TI - Hypothermia. 3. Try to avoid cold comfort. PMID- 6904019 TI - Community nursing--psychiatric geriatric service. Just one makes all the difference. PMID- 6904017 TI - Preventive health care policies. Dreaming of an ideal world. PMID- 6904020 TI - 'Briggs' crosses Irish Sea. PMID- 6904021 TI - A mental nurse is an advantage. PMID- 6904022 TI - Parasitology 1. From the Arctic to the tropics. PMID- 6904023 TI - Pressure sores. Individuality equals success. PMID- 6904024 TI - Dangerous dust. PMID- 6904025 TI - Orthopaedics. 4. Joint treatment. PMID- 6904026 TI - Preparing nurses for Hickman catheter care: a self-learning module. PMID- 6904027 TI - Care at St. Christopher's. PMID- 6904028 TI - Vocal rehabilitation of the patient with a laryngectomy. II. Assessment for vocal rehabilitation. PMID- 6904029 TI - Vocal rehabilitation of the patient with a laryngectomy. III. Specific techniques in laryngectomee vocal rehabilitation. PMID- 6904030 TI - Ethical issues in cancer nursing. I. Defining the issues. PMID- 6904031 TI - Ethical issues in cancer nursing. II. Impediments to ethical nursing practice. PMID- 6904032 TI - Ethical issues in cancer nursing. III. The ANA's human rights guidelines for nurses in clinical and other research. PMID- 6904033 TI - Ethical issues in cancer nursing. IV. A model for ethical decision making. PMID- 6904034 TI - Nurses do care. PMID- 6904035 TI - Nursing actions in cancer chemotherapy administration. PMID- 6904036 TI - [Effect of various hypotensive drugs on the plasma level of kininogen and prekallikrein in hypertension]. PMID- 6904037 TI - Toward a new philosophy of nursing. PMID- 6904038 TI - Ethical dilemmas: on concealing mistakes. PMID- 6904039 TI - [Views on structure and function of elongation factor 1 (EF1) from Eucaryotes (author's transl)]. PMID- 6904040 TI - ["Professional emblem"]. PMID- 6904041 TI - [Patients must trust their nurses]. PMID- 6904042 TI - [Planned parenthood and active family planning]. PMID- 6904044 TI - [Advances in pediatric gastroenterology]. PMID- 6904043 TI - [Prevention of cross infection]. PMID- 6904045 TI - [The safety of patients]. PMID- 6904046 TI - ["Lwi Grod"]. PMID- 6904047 TI - [Hospital infections]. PMID- 6904048 TI - [How good health should be valued]. PMID- 6904050 TI - [Blood preservation]. PMID- 6904049 TI - [Personal conflict]. PMID- 6904051 TI - [Developmental esophageal abnormalities]. PMID- 6904052 TI - ["What should be discarded?"]. PMID- 6904053 TI - Family-centered maternity care. PMID- 6904054 TI - Needs assessment for hospital-based home care services. AB - Careful needs assessment is a prerequisite to addressing issues of health care program effectiveness and program planning from a population-based perspective. Home care program evaluation literature is lacking in examples of strategies for such assessment. A nurse-screening of admissions was conducted at an acute care general hospital to estimate need for hospital-based home care (HBHC) services among the 2,613 patients discharged from medical and surgical services over a 5 month period. After careful delineation of inclusion and exclusion criteria for identifying HBHC patients and participant-observer training, the nurse's judgments on patient appropriateness for HBHC care were shown to agree reliably with those of the HBHC staff (k = + .45). In the study hospital under current conditions, an estimated 64% of discharged patients appropriate for home care do not receive these services. A comparison of the incidence according to service of HBHC-appropriate patients and patient-referral rates to HBHC suggests that one service over-refers (neurology), but most under-refer. Screening nurse salary expenditures constitute the major costs of this approach to home care needs assessment, which is recommended only for addressing major, infrequent programmatic policy issues. PMID- 6904055 TI - Anxiety levels and concerns among pregnant women. AB - Since maternal anxiety has been implicated as one variable in the etiology of maternal and fetal complications, this study was done to identify specific concerns and anxiety levels among pregnant women. One hundred pregnant women, 48 private and 52 clinic patients, completed the Taylor Manifest Anxiety Scale, a concerns questionnaire, and an information sheet. Twenty-nine specific concerns were identified by 50% or more of the pregnant women. Major concerns identified were "if your baby will be healthy and normal" (94%) and "your baby's condition at birth" (93%). The number of expressed concerns showed a statistically significant correlation with anxiety level (rs = .5678; p = .001), with clinic patients having significantly higher anxiety levels than private patients. PMID- 6904056 TI - Toward scholarliness in doctoral dissertations: an analytical model. AB - The dissertation is one of the most important vehicles for providing the novice researcher with the necessary socialization for a future of productive and scholarly research activities. Research productivity and the scholarliness of research are needed in developing nursing science. In this article, the processes that have the potential to enhance the quality of the doctoral dissertation are addressed; the psychological, social, and structural processes involved in completing a quality dissertation are delineated and discussed; and a model for the development of scholarliness and scholarship in doctoral programs is presented. The authors address three major areas for consideration: (a) the dependence of scholarship and scholarliness on researchable questions that are important, evolve in the context of theoretical considerations, and improve the scientific base of nursing knowledge; (b) the development of these qualities as enhanced by the resolution of several dilemmas that revolve around decisions made throughout the dissertation process; and (c) the recomendation that these qualities (scholarship and scholarliness) be fostered meticulously during doctoral education in nursing and, preferably, earlier. PMID- 6904057 TI - Commitment to research: the most important ingredient. PMID- 6904059 TI - [alpha-n-benzoylarginine-2-naphthylamide-amidohydrolase activity in chicken liver (author's transl)]. AB - The enzyme activity from chicken liver that hydrolizes alpha-N-benzoil-DL arginine-2-naphthylamide (BANA) has been separated into three active fractions by chromatography on Sephadex G-100 and DEAE-cellulose. The enzyme in Fraction FEA has a molecular weight greater than or equal to 100,000. The other two enzymes in Fractions FE1B and FE2B have a molecular weight around 23,000 and are separated by DEAE-cellulose chromatography. The BANA-hydrolase of fraction FE2B is unstable at pH alkaline and activates trypsinogen, in contrast with the enzyme of fraction FEB1. Both are thiol enzymes which behave analogously against activators (cysteine, dithiotreitol and 2-mercaptoethanol) and inhibitors (PCMB, IAA, N ethylmaleimide, Cu2+, Hg2+ and Zn2+). PMID- 6904058 TI - Employment activity of baccalaureate and diploma nurses. AB - In this study, the general hypothesis tested was that differences in rate of employment activity between baccalaureate and diploma nurses are due to effects of extraneous and intervening variables and not to intrinsic differences in the educational process. Mailed questionnaires from 1,475 nurses registered in the State of Indiana provided data on two measures of employment activity, as well as four control variables: marital status, spouse's income, presence of young children at home, and disillusionment with career. Among recent graduates, there was a negative association between possession of the baccalaureate degree and current employment status (gamma = -.359, p < .05). It was expected that holding constant the four control variables would reduce this association to or near zero. The opposite was generally the case, however; controlling for marriage, children, and disillusionment actually increased the association between type of education and employment status. Differences in employment activity between the two types of graduates therefore can not be accounted for by "traditional" variables used in the study of female labor-force participation. PMID- 6904061 TI - Commitment falls short of renewal. PMID- 6904060 TI - Continuing education: SDL in Sudbury. PMID- 6904063 TI - Make the most of life. PMID- 6904062 TI - To thine own self be true: ethical dilemmas in nursing. PMID- 6904064 TI - Bottle babies: the Nestle boycott. The bottle baby scandal. PMID- 6904065 TI - Synergism of the toxicity of physostigmine and neostigmine by lithium or by a reserpine-like agent (Ro4-1284). AB - A single sublethal i.p. dose of lithium chloride (300 mg/kg or 7.1 meq/kg) followed 12 h later by an otherwise sublethal s.c. dose of physostigmine sulfate (1.0 mg/kg) resulted in 90% mortality among male rats following a pronounced cholinergic syndrome, including convulsions. This confirms a previous report of a lethal synergism of physostigmine after subacute dosing with lithium. Mortality could be completely prevented by 1.0 mg/kg of atropine sulfate given 30 min before physostigmine, but was incompletely, if at all, reduced by selective peripheral cholinergic blockers, methylatropine bromide (0.5, 1.5 mg/kg) or glycopyrrolate (1 mg/kg). This suggested a predominantly central site for the toxic interaction. However, a similar synergism of lethality caused by neostigmine methylsulfate (0.3 mg/kg, s.c.) after treatment with lithium, which could be eliminated by methylatropine or glycopyrrolate, indicates that lithium may also produce lethal synergism of a cholinesterase (ChE) inhibitor that does not act centrally. Ro4-1284, an agent that has reserpine-like actions, was tested in combination with physostigmine or neostigmine; it showed synergism of toxicity nearly the same as in the case of lithium plus the cholinergic agents. These findings support the hypothesis that lithium causes the toxic synergism via a reduction of adrenergic activity, leading to an imbalance between adrenergic and cholinergic influences and a consequent failure to tolerate the effects of the ChE inhibitors. A potential hazard for the clinical use of physostigmine and neostigmine, concurrently with lithium or reserpine-like agents, it suggested. PMID- 6904066 TI - Test your knowledge: time management. PMID- 6904067 TI - The clinical pathology laboratory. Examination of the bone marrow. PMID- 6904068 TI - Ultrasonography: a new diagnostic technique for veterinary medicine. PMID- 6904069 TI - Chemical keratitis in a horse. PMID- 6904070 TI - Feline upper respiratory disease: a review. PMID- 6904071 TI - Butorphanol tartrate: a new antitussive agent for use in dogs. PMID- 6904072 TI - A severe case of acute suppurative dermatitis with disseminated intravascular coagulation in a dog. PMID- 6904073 TI - Clinical chemistry and pathophysiology of horses. A data base for abdominal pain- 1. PMID- 6904074 TI - Contagious equine metritis. PMID- 6904075 TI - Surgical removal of uropygial gland tumor in budgerigars. PMID- 6904076 TI - Cesarean delivery in the snake. PMID- 6904077 TI - Food animal regional anesthesia. bovine blocks: cornual. PMID- 6904078 TI - Mastitis caused by teat-dipping error. PMID- 6904079 TI - Urea poisoning in a commercial dairy herd. PMID- 6904081 TI - The veterinarian's role in feedlot practice. PMID- 6904080 TI - Surgical repair of a perforated ruminal ulcer associated with left displacement of the abomasum in a Jersey cow. PMID- 6904082 TI - So you're going to give a talk! I know you hear me, but are you listening? PMID- 6904083 TI - Tax-wise: tidbits of tax savvy that could save you money. PMID- 6904084 TI - An effective reminder system using the mini-computer. PMID- 6904085 TI - A complication following ovariohysterectomy in a dog. PMID- 6904086 TI - Ablation of the ear canal for treatment of chronic suppurative otitis externa in a cat. PMID- 6904087 TI - Splenic sporotrichosis in a dog. PMID- 6904088 TI - Hyperplastic goiter in a budgerigar. PMID- 6904089 TI - Lead poisoning in a parakeet. PMID- 6904090 TI - Food-animal regional anesthesia: bovine blocks: epidural. PMID- 6904092 TI - Differentiating between right displaced abomasum and cecal torsion in cows. PMID- 6904091 TI - Disseminated intravascular coagulopathy (DIC) in a cow with left displaced abomasum, metritis, and mastitis. PMID- 6904094 TI - Bovine estrus synchronization--2: a checklist for client counseling. PMID- 6904093 TI - Tick paralysis in a calf. PMID- 6904095 TI - Plasma levels of sulfadimethoxine in swine given the medication in their water. PMID- 6904096 TI - Urology--2: testing for renal disease. PMID- 6904097 TI - Full Kirschner splint repair of a fractured radius in a foal. PMID- 6904098 TI - A method of repairing a fractured core of the horn in an exotic ungulate. PMID- 6904099 TI - Repair of abdominal hernia in a Gila monster (Heloderma suspectum). PMID- 6904100 TI - Keeping salaries secret: help or hindrance? PMID- 6904102 TI - The block scrub: systematic preparation for aseptic surgery. PMID- 6904101 TI - Changing perspectives on attitudes toward animals and client relations in veterinary practice--2. PMID- 6904103 TI - The role of applied animal psychology in small animal medicine. PMID- 6904104 TI - The clinical pathology laboratory--6: anemias. PMID- 6904105 TI - Wrong diagnosis, right treatment: a learning experience. PMID- 6904107 TI - Electrocardiology of the anesthetized patient--2: treatment of arrhythmias and cardiac arrest. PMID- 6904106 TI - Surgical management of salter-type fractures in an immature dog -- a study in limb deformity. PMID- 6904108 TI - The clinical pathology laboratory; interpretation of the leukocytic hemogram. PMID- 6904110 TI - The sutureless nephrotomy closure: a photographic essay. PMID- 6904109 TI - Changing the eating habits of a dog: a case study. PMID- 6904111 TI - An ovarian cyst in a West Highland White Terrier. PMID- 6904113 TI - A simple inexpensive drill for orthopedic surgery. PMID- 6904112 TI - Dietary management of a dog with hepatic insufficiency suggestive of a portasystemic shunt. PMID- 6904114 TI - Patent ductus arteriosus in a kitten. PMID- 6904115 TI - Acute bilateral glaucoma. PMID- 6904116 TI - Synovial fluid. PMID- 6904117 TI - a retrospective study of the anesthetic management of adult draft horses. PMID- 6904118 TI - Salmonella-induced vaginitis. PMID- 6904119 TI - use of a colopexy to correct eversion of the cloacal mucosa in a mynah bird. PMID- 6904120 TI - Urethral dilatation in a steer: a case report. PMID- 6904121 TI - Food-animal regional anesthesia: bovine blocks: internal pudendal (pudic) nerve block. PMID- 6904122 TI - Albendazole treatment of experimentally induced Fascioloides magna infection in goats. PMID- 6904123 TI - A guinea pig monster. PMID- 6904124 TI - Using research in practice: selected issues in the translation of research to nursing practice. PMID- 6904125 TI - A questioning attitude. PMID- 6904126 TI - The cadence and chaos of change: CSULB revisited. PMID- 6904127 TI - Black and white elderly: morale and perception of control. PMID- 6904128 TI - Consumer activism in two women's self-help groups. PMID- 6904129 TI - Problems in doing research: how to maximize missing data and lose human subjects. PMID- 6904130 TI - Ethical issues in nursing research: events in 1980. PMID- 6904131 TI - Strategies for teaching nursing research: the language and importance of nursing research. PMID- 6904132 TI - Researchmanship: the judges and their judgments. PMID- 6904133 TI - A typology of detachment/involvement styles adopted during pregnancy by first time expectant fathers. PMID- 6904134 TI - Defining and measuring student success: a three-dimensional approach. PMID- 6904135 TI - The effect of an experimental teaching program on post-operative ventilatory function: a self-critique. PMID- 6904136 TI - Problems in doing research: an alternative to classical experimental design in clinical settings. PMID- 6904139 TI - Researchmanship: the revision of the protocol. PMID- 6904138 TI - Strategies for teaching nursing research: research preparation in baccalaureate nursing education. PMID- 6904137 TI - Ethical issues: a survey of institutional review boards. PMID- 6904140 TI - Patient strategies for managing maintenance hemodialysis. PMID- 6904141 TI - Describing a new baccalaureate nursing population: the second step. PMID- 6904142 TI - Parent's view of support following the loss of their infant to sudden infant death syndrome. PMID- 6904144 TI - Ethical issues in nursing practice. PMID- 6904143 TI - Practical suggestions for the use of the audio cassette tape recorder in nursing research. PMID- 6904145 TI - Using research in practice: a research-based model for patient education. PMID- 6904146 TI - Strategies for teaching nursing research. PMID- 6904147 TI - Researchmanship: a successful proposal for intramural funds. PMID- 6904148 TI - Current issues in nursing education: comments shared with Monongalia County Medical Society February 5, 1980. PMID- 6904149 TI - Where is psychiatric nursing going? PMID- 6904150 TI - Irish cancer in association with Hume St. Hospital study day. PMID- 6904152 TI - Interview with Dr. Shirley Stinson - President of Canadian Nurses Association. PMID- 6904151 TI - [Cerebrospinal fluid and blood kinins of patients with cerebral circulatory disorders]. AB - The kallikrein-kinin system components were examined in the cerebrospinal fluid and the blood of patients with acute cerebral circulation disorders at various intervals after the vascular episode. A considerable increase in the content of all the substances being examined in the patients' cerebrospinal fluid was shown, this increase being not dependent on the stroke character. An activation of the kallikrein-kinin system was observed in the blood plasma within the first 20 days after the vascular episode. In young patients, these changes were more pronounced. The changes in the kallikrein-kinin system components, along with those of other vasoactive substances may take a certain part in the pathogenetic mechanisms of the cerebral stroke. PMID- 6904154 TI - A study to determine the relationship between the level of patient satisfaction and care given by the nurse-physician team. PMID- 6904153 TI - Messenger role of calcium in function of pancreatic acinar cells. AB - Enzyme secretion from the exocrine pancreas is elicited by a) cholinergic stimulants, b) hormones belonging to the family of pancreozymin, c) some amphibian peptides such as bombesin, eledoisin, and physalaemin, and d) secretin and vasoactive intestinal polypeptide. Whereas the mechanism of the group d hormones in stimulating enzyme secretion involves adenosine 3',5'-cyclic monophosphate, the others seem to use a common pathway involving Ca2+ as intracellular messenger and probably guanosine 3',5'-cyclic monophosphate as modulator of their action. Their effects can be ascribed to two processes. One pathway involves release of Ca2+ from an intracellular store that is most likely located in the plasma membrane. This phase is independent of extracellular Ca2+ and leads to a rise of guanosine 3',5'-cyclic monophosphate. The other pathway is characterized by an increased permeability of the plasma membrane for Ca2+ and is necessary for sustained secretion. Both pathways lead to an increase cytosolic free Ca2+ concentration. Ca2+ is either directly involved in fusion of zymogen granules with the luminal cell membrane or triggers events that lead to exocytosis. Furthermore, augmented cytosolic-free calcium concentration a) increased the plasma membrane permeability for Na+, Cl-, and K+, which leads to depolarization of the cell, and b) induces uncoupling of neighboring acinar cells. PMID- 6904155 TI - A survey of nurses' ideas about nursing practice concerns and professional organizations. PMID- 6904156 TI - Nurse leader urges change in hospital power structure. PMID- 6904157 TI - Nursing is a rich and confusing experience. PMID- 6904158 TI - Work conditions cause nurses to leave. PMID- 6904160 TI - The real purpose of the scrub suit. PMID- 6904159 TI - Methicillin-resistant Staphylococcus aureus: introduction and spread within a hospital. AB - In March 1978, a strain of methicillin-resistant Staphylococcus aureus was introduced from the community into a university hospital. Within 6 months of admission of the index case, methicillin-resistant S. aureus was isolated from 30 additional patients, 22 of whom were epidemiologically linked by a common phage type (6/47/54/75/83A) and roommate-to-roommate spread. Sixteen of 31 cases were infected, six with bacteremia. Patients with infections received cephalosporins more frequently before infection than did control subjects (p < 0.05). Patients acquiring methicillin-resistant S. aureus in the intensive care unit had a longer mean stay, had higher overall mortality, and received nafcillin and aminoglycosides more frequently than did cohorted control subjects. By mid-1979, methicillin-resistant S. aureus accounted for 38%, 31%, and 24% of all nosocomial S. aureus postoperative wound, pulmonary, and bloodstream infections, respectively. In hospitals with significant methicillin-resistant S. aureus isolation rates, initial empiric therapy of presumed S. aureus infection with vancomycin seems warranted. PMID- 6904161 TI - Does your patient need a PhD to read your consent form? PMID- 6904162 TI - Your OR suite can be a good learning environment. PMID- 6904163 TI - Avoid using brush to clean instruments during procedures. PMID- 6904164 TI - Carotid endarterectomy: before surgery. PMID- 6904165 TI - Carotid endarterectomy: care in the OR. PMID- 6904167 TI - Advising patients on sex after surgery. PMID- 6904166 TI - Carotid endarterectomy: after surgery. PMID- 6904169 TI - Obtaining patient's informed consent a dual responsibility. PMID- 6904168 TI - Ideal attitudes of a nurse researcher. PMID- 6904170 TI - Taking the mystery out of chest tubes. PMID- 6904171 TI - HHS publishes regs to permit technicians to circulate in the OR. PMID- 6904172 TI - Kock pouch: a new type of ileostomy. PMID- 6904173 TI - Nursing care of the Kock pouch patient. PMID- 6904175 TI - FDA's standards policy for medical devices. PMID- 6904174 TI - An OR nurse in the African bush. PMID- 6904176 TI - Nurses have a say in device standards. PMID- 6904177 TI - AORN recommended practices for inhospital sterilization. PMID- 6904178 TI - Research language. PMID- 6904179 TI - Hospitals can set limits on functions of private scrubs. PMID- 6904180 TI - Have we created a frenzied world of exhausted superwomen? PMID- 6904181 TI - Current concepts in pain. PMID- 6904182 TI - OR observations: key to postop pain. PMID- 6904183 TI - Can OR garb be stylish and functional? PMID- 6904184 TI - Use purchasing clout to get information from manufacturers. PMID- 6904185 TI - Selecting a research problem. PMID- 6904187 TI - Nursing provides new mid-life career for mother of four. PMID- 6904186 TI - An improved method for posting surgery. PMID- 6904188 TI - A matter of opportunity. PMID- 6904189 TI - Maslow's needs and the spinal cord injured client. PMID- 6904190 TI - Research: findings and attitudes. PMID- 6904191 TI - Nursing as a profession. PMID- 6904193 TI - One method of progressive evaluation. PMID- 6904192 TI - The beginnings of my professional self. PMID- 6904194 TI - Queen Victoria Medical Centre: Birth Centre. PMID- 6904195 TI - A visit to an Aboriginal settlement. PMID- 6904196 TI - A maternity nursing course for RNA's. PMID- 6904197 TI - Personal view in the Great Debate. PMID- 6904198 TI - WHO studies the brain drain problem. PMID- 6904199 TI - Flucloxacillin sodium. PMID- 6904200 TI - Nursing education and patient care. PMID- 6904202 TI - Demystifing programme planning: a community nursing course for Queensland. PMID- 6904201 TI - Emergency resuscitation ethics and legalisms. PMID- 6904203 TI - A time to every purpose...and it is time we got back to care as the basis for all practice. PMID- 6904204 TI - Student selection for general nurse training at Australian tertiary institutions. PMID- 6904205 TI - Spiritual care and the nursing process. PMID- 6904206 TI - "Sticks and stones" - another contribution to the vitamin controversy. PMID- 6904207 TI - Education for survival of the individual, the society and the species. PMID- 6904208 TI - President favours nursing training in hospital environment. PMID- 6904209 TI - Nursing education. PMID- 6904210 TI - The matter of framework (a conclusion drawn from two years of theory in AANT--May 78-April 80). PMID- 6904211 TI - Diet and coronary heart disease. PMID- 6904212 TI - Dealing with controversial moral issues in schools of nursing. PMID- 6904213 TI - Applying standards to practice. PMID- 6904214 TI - Traditional reverence is changing. PMID- 6904215 TI - I am a handicapped child. PMID- 6904216 TI - Joggers - beware. PMID- 6904217 TI - Clinical interpretation of arterial blood gases. PMID- 6904218 TI - Diversional therapy--some suggestions for activities aides. PMID- 6904220 TI - Reversal of role: from nurse to patient. PMID- 6904219 TI - Ashford passes strict two-day test with flying colors. PMID- 6904221 TI - Management patterns and present practice. PMID- 6904222 TI - Collaboration in care: doctor and nurse roles, community health nursing, practice and education. PMID- 6904223 TI - First aid for nurses. PMID- 6904224 TI - A country diabetic clinic. PMID- 6904225 TI - Viral vaccines vital or vulnerable. PMID- 6904226 TI - Studies on a leukocyte elastase inhibitor present in the culture medium of inflamed synovial tissue. PMID- 6904227 TI - A look at career mobility: education's response. 1. PMID- 6904228 TI - Reciprocity agreement. PMID- 6904229 TI - The modern Christmas--celebration without purpose? PMID- 6904230 TI - Ageless values. PMID- 6904231 TI - Hemostasis and the nature of its defect in hemophilia. PMID- 6904232 TI - A special hemophilia program. PMID- 6904233 TI - Primary nursing Do patients like it Are nurses satisfied Does it cost more? PMID- 6904234 TI - The postpartum period. What is reality? PMID- 6904235 TI - Man versus microbe: a case for the infection control nurse. PMID- 6904236 TI - Hepatitis B and occupational risk. PMID- 6904237 TI - Breast disease in nurses, a 30-year study. PMID- 6904238 TI - Shirley, a success story. PMID- 6904239 TI - Wanted! A new interface between administration, nursing and medical staff. PMID- 6904240 TI - Nursing's visions: dreams or reality? PMID- 6904241 TI - Malaria, a Canadian problem! PMID- 6904242 TI - Outport nursing in Newfoundland. PMID- 6904243 TI - That's me, a Prairie public health nurse. PMID- 6904244 TI - On becoming a public health nurse. PMID- 6904245 TI - A lesson in courage. PMID- 6904246 TI - How could we help Betty? PMID- 6904247 TI - Nursing the community. PMID- 6904248 TI - The health workshop. PMID- 6904249 TI - Working with a mother's group. PMID- 6904250 TI - Single parent children in school. PMID- 6904251 TI - Caring for foster children in the community. PMID- 6904252 TI - Bridging the gap between hospital and home. PMID- 6904253 TI - A province-wide ostomate program. PMID- 6904254 TI - Happy feet. PMID- 6904255 TI - Family support and friendly visiting. PMID- 6904256 TI - Computers, an administrative asset. PMID- 6904257 TI - Complement activation in Staphylococcus aureus bacteraemia. AB - Serum levels of complement components C3, C4 and factor B were measured in twenty five patients with Staphylococcus aureus bacteraemia. The levels of C3 were depressed in nine patients, five of whom also had low C4 levels, indicating activation of complement via the classical pathway. Two patients with low C3 levels also had low factor B levels, one of these being in association with a low C4 level, which indicates activation of both the classical and alternative pathways, the latter being via the C3b feedback cycle. The protein A content of the S. aureus cultures, as shown by the indirect haemagglutination titre, was high in nine patients with C3 hypocomplementaemia. There was some correlation between the presence of a high protein A content of the S. aureus culture and a low serum C3 level in the patient. Some clinical evidence of immune complex disease was found in three patients. Complement activation in S. aureus bacteraemia is most likely due to complex formation resulting from the interaction between the Fc portion of IgG and staphylococcal protein A. These complexes may also result in clinical symptoms of immune complex disease. PMID- 6904258 TI - Community outlook. A challenge! PMID- 6904259 TI - Talking about dying. PMID- 6904260 TI - Breast feeding--my way. PMID- 6904261 TI - Breast feeding--my way. PMID- 6904262 TI - Dark skin assessment: a self quiz. PMID- 6904263 TI - Legionella pneumophilia. PMID- 6904264 TI - Helping critical care nurses with work-related stress. PMID- 6904265 TI - The mystique surrounding "how to discontinue ventilator support". PMID- 6904266 TI - Management of violent patients. PMID- 6904268 TI - Burnout. PMID- 6904267 TI - Child abuse has no class. PMID- 6904269 TI - Stress. PMID- 6904270 TI - Synergy: a technique for managing stress. Psychosocial update! PMID- 6904271 TI - Clinical and medico-legal considerations in the management of gunshot wounds. PMID- 6904273 TI - Alcoholism and the alcoholic client. PMID- 6904272 TI - Acute disseminated intravascular coagulation. PMID- 6904274 TI - Intravenous techniques. PMID- 6904275 TI - Aspirin update! PMID- 6904277 TI - Behavioral pediatrics in nursing, a behavior modification approach. PMID- 6904276 TI - Pulmonary embolism. PMID- 6904278 TI - Enuresis: guidelines for nursing management. PMID- 6904279 TI - The nurse and the sexually assaulted child. PMID- 6904280 TI - Nursing implications in camps for children with diabetes. PMID- 6904281 TI - Reye's syndrome: epidemiology and treatment. PMID- 6904282 TI - The crisis of the first child. PMID- 6904283 TI - Role of the clinical specialist in the pediatric intensive care unit. PMID- 6904284 TI - The nurse's role in transporting the critically ill child. PMID- 6904285 TI - Role of the pediatric nurse practitioner as a health coordinator in a preschool. PMID- 6904286 TI - Social support and life change during early family development. PMID- 6904287 TI - The challenge of adoption. PMID- 6904288 TI - The impact of the motherhood myth on women. An approach to nursing care. PMID- 6904289 TI - Impairments of motherhood: causes and implications for nursing intervention. PMID- 6904290 TI - Jaundice in the neonate: theory practice. PMID- 6904291 TI - Neurological assessment during the first year of life. PMID- 6904292 TI - Home blood glucose monitoring: benefits for the patient and educator. PMID- 6904293 TI - Meeting the needs of the parents of children with diabetes--a babysitter's course. PMID- 6904294 TI - Diabetic retinopathy and laser photocoagulation: a personal view. PMID- 6904295 TI - Making behavioral objectives meaningful. PMID- 6904296 TI - [Current focus on care of newborn infants]. PMID- 6904297 TI - [Planning for research in nursing]. PMID- 6904298 TI - ["Nursing Day"]. PMID- 6904299 TI - Stoichiometry of interaction of chicken ovoinhibitor with pancreatic trypsin, chymotrypsin and elastase I. AB - 1. The interaction of chicken ovoinhibitor with pancreatic trypsin, chymotrypsin and elastase I was studied in the absence of substrate by affinity chromatography, electrophoresis and gel filtration. 2. It was found that ovoinhibitor has, at least, five separate and non-overlapping binding sites: two for trypsin, two for chymotrypsin and one for elastase. Most likely, all five sites may be occupied simultaneously. 3. Electrophoretic studies indicated that two binding sites for trypsin and probably also for chymotrypsin differ in their affinity toward the respective enzyme. PMID- 6904300 TI - Complement studies in children with treated coeliac disease after gluten challenge. AB - Changes of the complement components in the sera of 13 children with treated coeliac disease were studied after gluten challenge. The levels of C 1 and C3 activator (factor B) were significantly decreased at 4 h after the challenge, as were the levels of total complement (CH 50) and the components C 1, C 4 and C 1 inactivator at 8 h. After 24 h most values returned to normal but there was another significant decrease in serum C 4 after 24 h, and for CH 50, C 1, C 2 and C 4 after 48 h. PMID- 6904302 TI - Mechanism of codon-anticodon interaction in ribosomes: codon-anticodon interaction of aminoacyl-tRNA at the ribosomal donor site. PMID- 6904301 TI - Male mouse submaxillary gland secretes highly toxic proteins. AB - Submaxillary gland saliva induced by phenylephrine from male mice was highly toxic to guinea-pigs, rats and hamsters, whereas the toxicity was relatively low to mice. One of the toxic components in the saliva was isolated as a kallikrein like enzyme. PMID- 6904303 TI - [Sources of tuberculous infection and the main methods for their detection]. PMID- 6904304 TI - [Methods for the direct examination of the patient in therapy. II. The study of organs and systems]. PMID- 6904305 TI - [Cesarean section in modern obstetrics]. PMID- 6904306 TI - [Prevention of kidney calculi]. PMID- 6904307 TI - [Medical control on the railroads before a run]. PMID- 6904308 TI - [Diagnosis of cutaneous tuberculosis]. PMID- 6904309 TI - [Clinical aspects, diagnosis and treatment of psoriasis]. PMID- 6904310 TI - [Transportation of patients and victims during natural disasters and catastrophes]. PMID- 6904311 TI - [Control of drunkenness and alcoholism (facts and figures)]. PMID- 6904312 TI - [Individual prevention of occupational hearing loss]. PMID- 6904313 TI - [Clinically contracted pelvis]. PMID- 6904314 TI - [Renal colic]. PMID- 6904315 TI - [Myocardial infarct]. PMID- 6904316 TI - [Early detection of pulmonary tuberculosis in the middle-aged and elderly]. PMID- 6904317 TI - [Prevention of rheumatism and its recurrence]. PMID- 6904318 TI - [Direct observation method with the patient in therapy]. PMID- 6904319 TI - [Characteristics of diabetes mellitus in older persons]. PMID- 6904320 TI - [Blood loss in multiple and combined injuries]. PMID- 6904321 TI - [Soporific and sedative preparations]. PMID- 6904322 TI - [Sex education of children and adolescents]. PMID- 6904323 TI - [Multiple myoma of the uterus and menorrhagia]. PMID- 6904324 TI - [Chronic erythematosis. The discoid form of lupus erythematosus]. PMID- 6904325 TI - [Listeriosis]. PMID- 6904326 TI - [The status of women and children in Denmark]. PMID- 6904327 TI - [Radiotherapeutic nursing care in breast cancer]. PMID- 6904328 TI - [Infertility studies in women]. PMID- 6904329 TI - [Treatment of breast cancer]. PMID- 6904330 TI - [The European nurse in Belgium; the Belgian nurse in Europe]. PMID- 6904332 TI - Of advocacy, ethics and love. The AJN Writing Contest. PMID- 6904331 TI - [Trends in our population growth]. PMID- 6904333 TI - A national credentialing center: are we ready to take a position? PMID- 6904334 TI - Keynote Address: A nice beginning for "Communicating together for action"! PMID- 6904335 TI - You and the law. PMID- 6904336 TI - The socially isolated elderly. PMID- 6904337 TI - How many others? PMID- 6904339 TI - A water bed that works...and costs only pennies. PMID- 6904338 TI - Why the patient called for help. PMID- 6904340 TI - A comparison of care in a Scottish and a United States facility. PMID- 6904341 TI - Learning about aging from the aged. PMID- 6904342 TI - Project independence. PMID- 6904343 TI - Breaking the silence. PMID- 6904344 TI - Common concern: research--the ultimate service. PMID- 6904345 TI - What does a good drug history include? PMID- 6904346 TI - Feeding the patient who has cancer. PMID- 6904347 TI - Synthesis and analytical use of 3-carboxypropionyl-alanyl-alanyl-valine-4 nitroanilide: a specific substrate for human leukocyte elastase. AB - A simple synthesis is described for 3-carboxypropionyl-Ala-Ala-Val-4 nitroanilide, a convenient and very specific substrate for human leukocyte elastase (Km = 1.0mM, kcat = 8.7 s-1). The substrate does not undergo appreciable spontaneous hydrolysis. It is not cleaved by trypsin or chymotrypsin and only rather slowly by porcine pancreatic elastase (Km = 9.1mM, kcat = 1.4 s-1). PMID- 6904349 TI - Adolescent pregnancy. PMID- 6904348 TI - Service and education: inefficient dichotomy? PMID- 6904350 TI - Men in nursing: a continuing struggle. PMID- 6904351 TI - To strike...or not to strike...? Who will control nursing practice. PMID- 6904352 TI - Spiritual needs and nursing responsibility. PMID- 6904353 TI - The nurse's role in primary prevention in sexual health. PMID- 6904355 TI - Sexual problems of the post coronary patient. PMID- 6904354 TI - Human sexuality content: should this be included in the baccalaureate nursing programs. PMID- 6904356 TI - Sex and pregnancy. PMID- 6904357 TI - The nurse as patient advocate. PMID- 6904358 TI - Computers in health care--the present and potential. PMID- 6904359 TI - The importance of touch in patient care. PMID- 6904361 TI - [Cancer of the exocrine pancreas]. PMID- 6904362 TI - [Selecting an access vein]. PMID- 6904360 TI - Interactions of chrysotile asbestos fibres with the complement system. AB - Type A chrysotile fibres (white asbestos) were tested in vitro for activation of the complement system. Fibres were incubated in normal human serum (NHS), factor B-depleted human serum, and normal and C4-deficient guinea-pig sera; the supernates were assayed for the remaining complement activity. Activation of the alternative pathway (AP) was shown in three ways. First, quantitative measurement of factor B; second, kinetic analysis of rabbit red blood cell lysis in whole alternative pathway (AP) and factor B lytic assays; third, qualitative measurement of C3 and factor B conversion by crossed immunoelectrophoresis. No C3 convertase activity could be demonstrated on the fibres but other possible mechanisms of AP activation are discussed. Magnesium itself is not responsible for this activation because acid-treated fibres retain this property. The early classical pathway is not involved as shown by normal whole complement activity of a factor B-depleted human serum and the absence of decrease of C4 functional activity. Knowing that complement proteins are present in pulmonary alveoli, mainly provided by cell synthesis, we suggest that complement activation in vivo may be relevant to the genesis of the chronic inflammation and fibrosis in the lung. PMID- 6904363 TI - [Cardiac physiology]. PMID- 6904366 TI - [Cicatrization of atonic vascular ulcers]. PMID- 6904365 TI - [Cerebrospinal fluid studies]. PMID- 6904367 TI - [Use of water beds to promote cicatrisation of burns]. PMID- 6904368 TI - [Conceptual diagram and evaluation of the quality of health care]. PMID- 6904364 TI - [Anorexia nervosa in the young girl]. PMID- 6904369 TI - [Louise Gauthier, nursing in Thailand. Interview by L.K. Crone]. PMID- 6904370 TI - [Curing alcoholism at the employment site]. PMID- 6904371 TI - [Training in psychosocial activities of daily living in a psychiatric hospital]. PMID- 6904372 TI - [The nurse and the obese patient. Obesity, a form of malnutrition]. PMID- 6904373 TI - [Triage, an efficient reality]. PMID- 6904374 TI - [Outdoor meals, picnic basket and lunch box]. PMID- 6904375 TI - [Nurses' labor unions, professional associations and you. The nurses unionize. 1]. PMID- 6904377 TI - [Legal aspects. Legal responsibility of the patient]. PMID- 6904376 TI - [The cosmetics industry]. PMID- 6904378 TI - [A new administrative council begins its' work by the creation of committees]. PMID- 6904379 TI - [Orem's conceptual model and its impact on nursing care. II]. PMID- 6904380 TI - [Nursing services in the prison environment]. PMID- 6904381 TI - [Nurse's day in the correctional environment]. PMID- 6904382 TI - [Occupational health nursing and community health]. PMID- 6904383 TI - [La Redoute... formidable automation]. PMID- 6904384 TI - [Me, I eat well!]. PMID- 6904385 TI - [Was the patient sufficiently informed? Legal aspects]. PMID- 6904386 TI - [A study term in the school environment in France]. PMID- 6904387 TI - [Written observations of the nurse]. PMID- 6904388 TI - [The role of the supervisory nurse in work relations (II)]. PMID- 6904389 TI - [Depression and the elderly person]. PMID- 6904390 TI - [The coal mines of the Bassin du Nord and the Pas de Calais...adapting work to man]. PMID- 6904391 TI - [Legal aspects: the student nurse and the law]. PMID- 6904392 TI - Should there be an association of hospital epidemiologists? PMID- 6904393 TI - Hospital-acquired myiasis. AB - In three years we encountered two patients with hospital-acquired myiasis, a rarely reported nosocomial problem. Both patients were elderly and had lengthy thoracic surgery in August in the same operating room. Larvae removed from the nares of one patient and from the chest incision of the other were of the same species, Phaenicia serricata. There was no evidence of tissue destruction or invasion in either case. Investigation revealed several factors that contributed to the presence of flies in the operating room. After a presumed environmental access site was closed and insecticide spraying was augmented, no additional cases occurred. This experience illustrates an unusual problem that may confront those responsible for infection control programs. PMID- 6904394 TI - Two epidemics of pseudobacteremia due to Staphylococcus aureus and Aerococcus viridans. AB - Two epidemics of pseudobacteremia are reported. The first, due to Staphyloccus aureus, was caused by a physician who had active staphylococcal skin infection and nasal colonization. Because the blood culture system in use at the time was open, and used screw cap bottles, we assume that the physician contaminated the bottles at the time of inoculation. The second outbreak, caused by Aerococcus viridans, was traced to contamination of the blood culture bottle tops as they were received from the manufacturer. We assume that there was inadequate disinfection of the bottle tops by the physicians prior to their use. PMID- 6904395 TI - Recommendations for the control of Yersinia pestis infections. Recommendations from the CDC. AB - Yersinia pestis, the etiologic agent of plague, is endemic in the western United States; 105 cases were reported between 1970 and 1979. Plague may manifest in one of three clinical forms; bubonic, septicemic, or pneumonic. Bubonic and septicemic plague represent relatively little risk for human-to-human transmission to contacts, although heavily infected secretions, such as drainage from a bubo, pose a theoretical risk, especially if they are aerosolized from a syringe during diagnohree clinical forms; bubonic, septicemic, or penumonic. Bubonic and septicemic plague represent relatively little risk for human-to-human transmission to contacts, although heavily infected secretions, such as drainage from a bubo, pose a theoretical risk, especially if they are aerosolized from a syringe during diagnohree clinical forms; bubonic, septicemic, or penumonic. Bubonic and septicemic plague represent relatively little risk for human-to-human transmission to contacts, although heavily infected secretions, such as drainage from a bubo, pose a theoretical risk, especially if they are aerosolized from a syringe during diagnostic aspirations. Pneumonic plague may be highly contagious to contacts and poses a greater risk. The Plague Branch, Center for Disease Control recommends that all patients with plague be placed in strict isolation for the first 48 hours of treatment because of the possibility that pneumonia may supervene. If it does not, wound and skin precautions are adequate for the duration of hospitalization. Untreated plague pneumonia is an epidemiologic emergency. All contacts must be identified promptly and those with face-to-face exposure should receive abortive antibiotic therapy. All contacts should be under surveillance, with twice-daily temperature checks, for seven days. PMID- 6904396 TI - Infection control: old myths and new realities: N.F.I.D. lecture. PMID- 6904397 TI - Health education in the Bush. PMID- 6904399 TI - Nursing in primary health care in Brazil. PMID- 6904398 TI - Development of primary health care. PMID- 6904400 TI - Unification of nursing practice, education and research. PMID- 6904401 TI - The new emphasis on traditional medicine in Zaire--implications for nursing practice. PMID- 6904402 TI - Community participation in evaluation: problems and potentials. PMID- 6904403 TI - To whom is NCSBN accountable? PMID- 6904404 TI - The single score: a controversial issue. PMID- 6904405 TI - Professional/legal definitions: are there differences? PMID- 6904406 TI - Why licensure? PMID- 6904407 TI - Boards for nursing - an educational program. PMID- 6904408 TI - National Council faces future. PMID- 6904409 TI - State board test pool: a retrospective view. PMID- 6904410 TI - Real issues behind the critical care nursing shortage. PMID- 6904411 TI - Incidence of disseminated intravascular coagulation in patients admitted through the emergency department: a 5 year retrospective study. PMID- 6904412 TI - Closing the communication gap between physicians and nurses in the intensive care unit setting. PMID- 6904413 TI - A clinical nurse specialist-social worker team on a cardiovascular surgery service. PMID- 6904414 TI - Evaluation of an inpatient educational program for coronary patients and families. PMID- 6904415 TI - Varying the timing of information to alter preoperative anxiety and postoperative recovery in cardiac surgery patients. PMID- 6904416 TI - Cost and utility considerations in implementing ambulance telemetry. PMID- 6904417 TI - Massive bilateral hydrothorax and hydromediastinum: an unusual complication of percutaneous internal jugular vein cannulation. PMID- 6904418 TI - Paroxysmal second-degree atrioventricular block induced by exercise. PMID- 6904419 TI - A study in intracardiac conduction. PMID- 6904420 TI - Does a diagnosis of sinoatrial block imply atrioventricular nodal disease? PMID- 6904422 TI - Usefulness of prophylactic bretylium in preventing ventricular fibrillation complication acute myocardial infarction. PMID- 6904421 TI - Sudden blindness-transient and permanent. PMID- 6904423 TI - Calculation of the rate of administration of parenteral medications as infusions. PMID- 6904424 TI - Troubleshooting the Swan-Ganz catheter. PMID- 6904426 TI - Improving the communication between nursing staff and hospitalized children. PMID- 6904425 TI - Notes on continuing education. PMID- 6904427 TI - Meeting the challenge of inservice education in rural Minnesota hospitals. PMID- 6904428 TI - Developing a model for implementation of an evaluation component in an orientation program. PMID- 6904429 TI - A nontraditional access model to nursing education. PMID- 6904430 TI - Self-assessment of learning needs: a tool to assist nurses in self-directed learning. PMID- 6904431 TI - The development of a nursing education record keeping system. PMID- 6904432 TI - Staff nurse preceptorship: an experiment for graduate nurse orientation. PMID- 6904433 TI - Nurses' experiences with dangerous behavior: implications for training. PMID- 6904434 TI - Through the eyes of continuing education--OCEAN, Inc. Providing continuing education for American nurses overseas. PMID- 6904435 TI - Processing a task group: a continuing education committee at work planning a conference. PMID- 6904437 TI - Budgetary management. PMID- 6904436 TI - Notes on continuing education: designing conference brochures. PMID- 6904439 TI - Methods of teaching--revisited audiotape recordings. PMID- 6904440 TI - Developing and marketing your continuing education programs. PMID- 6904441 TI - Developing and marketing your continuing education programs. Setting the stage. PMID- 6904438 TI - Adult teaching strategies. PMID- 6904442 TI - Case report: secondary syphillis with renal involvement. PMID- 6904443 TI - Home hemodialysis and the older patient. PMID- 6904444 TI - Providing systematic continuity of care for the end-stage renal disease client. PMID- 6904445 TI - Health care for the elderly. PMID- 6904446 TI - Elderly loneliness and it's relation to residential care. PMID- 6904447 TI - Planning and implementing a group health program on sexuality for the elderly. PMID- 6904448 TI - Effect of a course on aging in a graduate nursing curriculum: a small descriptive study. PMID- 6904449 TI - Training program for nursing assistants and LPNs in nursing homes. PMID- 6904450 TI - Do nurses have the power to cause, prevent, and cure "social breakdown syndrome"? PMID- 6904451 TI - Finding a new avenue for gerontological practice. PMID- 6904452 TI - A teaching program for the elderly on developmental tasks. PMID- 6904453 TI - Self-help for senior citizens. PMID- 6904454 TI - Relocation from a different perspective: deinstitutionalization and the elderly. PMID- 6904455 TI - Attitudes of the elderly toward religion. PMID- 6904456 TI - A wine bottle, plant, and puppy. Catalysts for social behavior. PMID- 6904458 TI - Perception of touch in the elderly. PMID- 6904459 TI - Effects of touch on self-appraisal and interaction appraisal for permanently institutionalized older adults. PMID- 6904457 TI - Psychoactive medication noncompliance in a geropsychiatric outpatient agency. PMID- 6904460 TI - With regard to aging, men and women are not equal. PMID- 6904461 TI - Corneal infections in mice with toxin A and elastase mutants of Pseudomonas aeruginosa. AB - The data presented indicate that in experimental infections of the mouse cornea, toxin A of Pseudomonas aeruginosa contributes to the organism's pathogenicity, whereas active elastase may not be required. After traumatization, corneas were infected with wild-type parental toxin A-producing strains, two toxin A-deficient mutants (Tox-), or an elastase mutant. The infections produced by both Tox- mutants were less severe than infections produced by their parental strains. Furthermore, the Tox- mutants were not able to persist in the eyes as long as their parental strains. Addition of subdamaging doses of exogenous toxin A to eyes infected with the Tox- mutant PA103-29 significantly increased is virulence. The course of infection and the resulting corneal damage produced by the elastase mutant were indistinguishable from those of its parental strain. PMID- 6904462 TI - The biosynthesis of transfer ribonucleic acid in the developing rat brain and in cultured glial cells. AB - The biosynthesis of tRNA was investigated in cultured astroglial cells and the 3 day-old rat brain in vivo. In the culture system astrocytes were grown for 19 days and were then exposed to [3H]guanosine for 1.5-7.5 h; 3-day-old rats were injected with [3H]guanosine and were killed 5-45 min later. [3H]tRNA was extracted, partially purified, and hydrolyzed to yield [3H]guanine and [3H]methyl guanines. The latter were separated from the former by high performance liquid chromatography and their radioactivity determined as a function of the time of exposure to [3H]guanosine. The findings indicate that labeling of astrocyte tRNA continued for 7.5 h and was maximal, relative to total RNA labeling, at 3 h, while in the immature brain tRNAs were maximally labeled at 20 min after [3H]guanosine administration. The labeling pattern of the individual methyl guanines differed considerably betweren astrocyte and brain tRNAs. Thus, [3H]1 methylguanine represented up to 35% of the total [3H]methyl guanine radioactivity in astrocyte [3H]tRNA, while it became only negligibly labeled in brain [3H]tRNA. Conversely, brain [3H]tRNA contained more [3H]N2-methylguanine than did astrocyte [3H]tRNA. Approximately equal proportions of [3H]7-methylguanine were found in the [3H]tRNAs of both neural systems. The [3H]methylguanine composition of brain [3H]tRNA was followed through several stages of tRNA purification, including benzoylated DEAE-cellulose and reverse phase chromatography (RPC-5), and differences were found between the [3H]methylguanine composition of RPC-5 fractions containing, respectively, tRNAlys and tRNAphe. The overall results of this study suggest that developing brain cells biosynthesize their particular complement of tRNAs actively and in a cell-specific manner, as attested by the significant differences in the labeling rates of their methylated guanines. The notion is advanced that cell-specific tRNA modifications may be a prerequisite for the successful synthesis of cell-specific neural proteins. PMID- 6904463 TI - Neuroglia: the forgotten cells of neurology. PMID- 6904464 TI - The epidemiology of primary brain tumors. PMID- 6904465 TI - The specialized role of the neurosurgical operating room nurse. PMID- 6904466 TI - Acute spinal cord injury and hyperbaric oxygen therapy: a new adjunct in management. PMID- 6904467 TI - Immunological aspects of malignant glial tumors. PMID- 6904468 TI - [Drug administration for ear, nose and throat]. PMID- 6904469 TI - [Introduction of diagnostic ultrasound]. PMID- 6904470 TI - [Perioperative fluids and electrolytes]. PMID- 6904471 TI - [Alcohol. Alcoholism. Alcoholic psychosis]. PMID- 6904472 TI - [Children in the world]. PMID- 6904473 TI - [Nursing care of lung cancer patients emphasizing chemotherapy]. PMID- 6904474 TI - [Nursing and law]. PMID- 6904475 TI - [Nursing care of patient with hypospadias]. PMID- 6904476 TI - A modular approach to management development. PMID- 6904477 TI - An interdisciplinary approach to holistic diabetic care. PMID- 6904478 TI - MATRIX: a unique patient classification system. PMID- 6904479 TI - Collaborative research development. PMID- 6904480 TI - Organizational factors in discharge planning. PMID- 6904481 TI - How much is a nurse-midwife worth? PMID- 6904482 TI - Outlooks on the future of nurse-midwifery. PMID- 6904483 TI - Father and childbirth: an anthropological perspective. PMID- 6904484 TI - Routine circumcision of the newborn: reasonable precaution or unnecessary risk? PMID- 6904485 TI - Geographic distribution of certified nurse-midwives. PMID- 6904486 TI - Customized cervical cap: evolution of an ancient idea. PMID- 6904487 TI - Diaphragm use instruction: time of insertion before coitus. PMID- 6904488 TI - Seminar on antimicrobial therapy III. The penicillins. PMID- 6904489 TI - Pneumococci relatively resistant to penicillin: a prevalence survey in children. PMID- 6904490 TI - Sleep disorders: recognizing them in patients. PMID- 6904491 TI - Help yourself! Give your patients a portion of good nutrition education. PMID- 6904492 TI - A nursing network to battle burnout. PMID- 6904493 TI - Assertiveness: it's a two-way street. PMID- 6904494 TI - Holiday cheer in a hospital? Can it occur? PMID- 6904495 TI - A page for your thoughts: what LP/VNs think of continuing education. PMID- 6904496 TI - RNs and LPNs: do they work well together? PMID- 6904497 TI - Writing an article for a nursing journal. PMID- 6904498 TI - Does continuing education equal competence? PMID- 6904499 TI - What should practical nurses be able to do. PMID- 6904500 TI - A profession with a future. PMID- 6904501 TI - Controlling hypertension: there are many roles for the LP/VN. PMID- 6904502 TI - Blood pressure measurement: techniques and tips for accurate readings. PMID- 6904503 TI - The guilt trip: when parents blame themselves--or others. PMID- 6904506 TI - Maternity nursing: what's so special about my specialty? PMID- 6904505 TI - CPR: more than "nice to know.". PMID- 6904504 TI - One reaction to guilt: denial. PMID- 6904507 TI - Caffeine and pregnancy: answers to common questions. PMID- 6904509 TI - Open-ended rectangular waveguides as antennas for medical diagnostics. AB - Open-ended rectangular waveguides, potentially useful as microwave antennas for medical diagnostics are described. Reflection coefficients have been measured for the waveguides fitted with standard flanges in contact with water and skin. Antenna matching to the tissue is discussed. Near-field radiation patterns in phantom solutions were measured to obtain operature and depth distribution patterns. PMID- 6904510 TI - Microwave radiation and heart-beat rate of rabbits. AB - Each of three adult New Zealand rabbits, 2 male and 1 female albinos, was exposed dorsally or ventrally, to 2450-MHz plane waves for 20 min under each of several field conditions: 1) to continuous waves (CW) at 5 mW/cm2; 2) to pulsed waves (PW) of 1-microsecond width that recurred 700 pps at an average of 5 mW/cm2 and at a peak of 7.1 W/cm2; 3) to PW of 10-microseconds width at a peak of 13.7 W/cm2 that were synchronized with and triggered by the R wave of the electrocardiogram (EKG) at various delay times (0, 100, and 200 ms; and 4) to CW at 80 mW/cm2. Carbon-loaded Teflon electrodes were used to record the EKG from forelimbs of an animal before, during, and after irradiation whilst it was maintained in a constant exposure geometry in a wooden squeeze box. Field induced changes in the heart-beat rate were observed at 80 mW/cm2 but not a lower average power densities, although a peak positive chronotropic effect might have been occasioned by PM introduced at 100 and 200 ms after the R wave peak. No cumulative effect was observed over a period of four months. Thermographic analysis revealed relatively little absorption of microwave energy by the myocardium irrespective of anatomical aspect of exposure. PMID- 6904508 TI - Physiological and behavioral effects of prolonged exposure to 915 MHz microwaves. AB - Long-Evans male adult rats were exposed for 16 weeks to 915-MHz CW microwaves at an average power density of 5 mW/cm2. The resulting dose rate was 2.46 (+/- 0.29 SEM) mW/g. The animals were exposed eight hours a day, five days a week, for a total of 640 h in a monopole-above ground radiation chamber while housed in Plexiglas cages. Daily measures of body mass and of food and water intake indicated no statistically significant effects of microwave irradiation. Measures by activity wheels and stabilimetric platforms of spontaneous locomotion indicate than mean activity levels increased about 25% after microwave exposure, but the findings are doubtful statistical significance (Ps < .10 but > .05). Studies of blood sampled after 2, 6, 10, and 14 weeks of exposure revealed alterations of free sulfhydryls. Measures of levels of urinary 17-ketosteroids at weeks 1, 5, 9, and 12 of exposure, and measures of brain hypothalamic tissue, and of mass of adrenals, heart, and liver at the end of the 16-week period, revealed no significant differences between irradiated and control animals. Cortical EEGs sampled after conclusion of microwave exposures also revealed no significant differences. PMID- 6904511 TI - Ouch! It's gout! PMID- 6904512 TI - Metric in-service training for hospital nurses. PMID- 6904514 TI - Commentary: the American health care system. PMID- 6904513 TI - Continuing education. Mandatory vs voluntary continuing education. PMID- 6904515 TI - Choice or change. PMID- 6904517 TI - The education of nurses: a rising national concern. National Advisory Council on Vocational Education. PMID- 6904516 TI - Commentary: health care and vacations. PMID- 6904518 TI - Overdose. PMID- 6904519 TI - Community organization for an oral cancer screening program. PMID- 6904520 TI - But the greatest of these is love. PMID- 6904521 TI - Continuing education. PMID- 6904522 TI - Commentary: upgrading of the LPN. PMID- 6904524 TI - Tuning out tinnitus. PMID- 6904523 TI - The beat goes on: anatomically speaking. PMID- 6904525 TI - Tuberculosis: diagnosis & treatment. PMID- 6904526 TI - Nursing procedure in elective cardioversion. PMID- 6904527 TI - Behavioral response to stress. PMID- 6904529 TI - Comments on the tentative standards for licensed practical nurse series & nursing assistant series to the Office of Personnel Management. PMID- 6904528 TI - Mastectomy: the experiences of twelve women. PMID- 6904530 TI - Continuing education. PMID- 6904531 TI - Commentary: need for LPNs. PMID- 6904533 TI - Spiritual care. PMID- 6904532 TI - Osteoporosis: the unnecessary crippler of women. PMID- 6904534 TI - Neurological disorders. PMID- 6904535 TI - Pharmacology: to crush or not to crush, that is the question. PMID- 6904536 TI - Continuing education. PMID- 6904537 TI - "Do as I say, not as I do.". PMID- 6904539 TI - Preparing for the interview. PMID- 6904538 TI - Commentary: health. PMID- 6904540 TI - Enzymes: life-sustaining catalysis. PMID- 6904541 TI - [Identity of women and childbirth: acquisition of identity by modern women]. PMID- 6904542 TI - [Identity of women and childbirth: development of maternal psychology and its effects]. PMID- 6904543 TI - [Identity of women and childbirth: assistance in the puerperal period, a case study]. PMID- 6904544 TI - [Identity of women and childbirth: child rearing and independence of the child]. PMID- 6904545 TI - [Identity of women and childbirth: roles of the father and mother]. PMID- 6904546 TI - [Identity of women and childbirth: women's identity and child rearing - my personal history (I)]. PMID- 6904547 TI - [Identity of women and childbirth: women's identity and child rearing - my personal history]. PMID- 6904548 TI - [Observation on the use of baby hotels (nurseries) in Tokyo by mothers]. PMID- 6904549 TI - [Management of pregnancy complicated by hyperthyroidism]. PMID- 6904550 TI - [Breast feeding and physiological weight loss of newborn infants]. PMID- 6904551 TI - [Continued nursing actions for the care of maternal and child health at A healthy facility (1). a health education class for mothers and its future plans]. PMID- 6904552 TI - [Prevention of neonatal asphyxia of low-birth-weigh infants]. PMID- 6904553 TI - [A Japanese midwife working in Tunisia]. PMID- 6904554 TI - [Innovation in nursing equipment. A sponge pillow]. PMID- 6904555 TI - [Innovation in nursing equipment. A lift sheet]. PMID- 6904556 TI - [Innovation in nursing equipment. A mouthwash tube]. PMID- 6904558 TI - [Innovation in nursing equipment. A stand for continuous drip infusion]. PMID- 6904557 TI - [Innovation in nursing equipment. An intubation set]. PMID- 6904559 TI - [Innovation in nursing equipment. Urine collection belt for a male patient]. PMID- 6904560 TI - [Innovation in nursing equipment. Restraining belt]. PMID- 6904562 TI - [Innovation in nursing equipment. A tracheal suction set container]. PMID- 6904561 TI - [Innovation in nursing equipment. A restraining belt for adult patients]. PMID- 6904563 TI - [Innovation in nursing equipment. An ice pack cover and a pillow]. PMID- 6904564 TI - [Innovation in nursing equipment. A bubbling mouthwash equipment]. PMID- 6904565 TI - [Innovation in nursing equipment. A multi-purpose bed frame]. PMID- 6904566 TI - [Innovation in nursing equipment. A comfort pillow]. PMID- 6904567 TI - [Innovation in nursing equipment. Improved cross-wise sheet and vinyl sheet]. PMID- 6904568 TI - [Innovation in nursing equipment. A bedside container]. PMID- 6904569 TI - [Innovation in nursing equipment. A ring shaped cushion filled with used panty hose]. PMID- 6904570 TI - [Innovation in nursing equipment. Breast pads for mastectomy patients]. PMID- 6904571 TI - [Innovation in nursing equipment. A support for a patient in a sitting position]. PMID- 6904572 TI - [Innovation in nursing equipment. Equipment for abduction exercises of the hip joint]. PMID- 6904573 TI - [Innovation in nursing equipment. A case housing ventricular drainage bottle]. PMID- 6904574 TI - [Innovation in nursing equipment. A balloon catheter traction stand]. PMID- 6904575 TI - [Innovation in nursing equipment. Pressure bandage to be applied after mastectomy]. PMID- 6904576 TI - [Innovation in nursing equipment. A belt for ureterostomy bag]. PMID- 6904577 TI - [Innovation in nursing equipment. A surgical garment for outpatients]. PMID- 6904578 TI - [Innovation in nursing equipment. An abdominal band and protection during bathing of patients with urinary diversion]. PMID- 6904580 TI - [Innovation in nursing equipment. A restraint belt for infants]. PMID- 6904579 TI - [Innovation in nursing equipment. Equipment to be worn after PTCD--with special reference to safety and fixation of the drainage equipment for walking]. PMID- 6904583 TI - [Innovation in nursing equipment. An eye-cover fixation band]. PMID- 6904581 TI - [Innovation in nursing equipment. A board for immobilizing infants during stereoscopic radiography]. PMID- 6904582 TI - [Innovation in nursing equipment. A hammock for extremely premature infants- weight measurement using a hanging scale]. PMID- 6904584 TI - [Innovation in nursing equipment. A restraint belt and specially designed pajamas for infants and young children]. PMID- 6904585 TI - [Innovation in nursing equipment. Touch-operated fixation device for drip infusion in children]. PMID- 6904586 TI - [Innovation in nursing equipment. A garment and board for fixation during drip infusion in children]. PMID- 6904587 TI - [Innovation in nursing equipment. A holder for medical records to be attached to the wheelchair]. PMID- 6904588 TI - [Innovation in nursing equipment. A bath tub to be used in the geriatric ward of a psychiatric department]. PMID- 6904589 TI - [Innovation in nursing equipment. A bedside medication box]. PMID- 6904592 TI - [Innovation in nursing equipment. An apron forming a large pocket in front]. PMID- 6904591 TI - [Innovation in nursing equipment. Equipment to measure hourly urinary output]. PMID- 6904593 TI - [Innovation in nursing equipment. A bathroom for the orthopedic department]. PMID- 6904590 TI - [Innovation in nursing equipment. A stand for a bed pan]. PMID- 6904594 TI - [Innovation in nursing equipment. A stand for bedpans]. PMID- 6904595 TI - [Innovation in nursing equipment. A wagon for medication distribution]. PMID- 6904597 TI - [Innovation in nursing equipment. A pocket attached to the bed]. PMID- 6904596 TI - [Innovation in nursing equipment. A tray for intravenous injections equipment]. PMID- 6904598 TI - [Innovation in nursing equipment. An apron to be worn during a round for temperature taking]. PMID- 6904599 TI - [Innovation in nursing equipment. A wagon for transport of urinary bags]. PMID- 6904600 TI - [Innovation in nursing equipment. A stainless steel stand for a medicine cup]. PMID- 6904602 TI - [Innovation in nursing equipment. A stand for drying ice packs]. PMID- 6904601 TI - [Innovation in nursing equipment. An emergency cart]. PMID- 6904603 TI - [Specificity of multiple injuries and their therapeutic system]. PMID- 6904604 TI - [Physiopathology of multiple injuries]. PMID- 6904605 TI - [Severity of multiple injuries]. PMID- 6904606 TI - [First aid in multiple injuries and therapeutic priority]. PMID- 6904607 TI - [Postoperative care in multiple injuries]. PMID- 6904608 TI - [Management of hemorrhagic shock in multiple injuries and respiratory care after shock]. PMID- 6904609 TI - [First aid in multiple injuries and the nursing system]. PMID- 6904610 TI - [Respiratory and circulatory care in the acute stage of multiple injuries- nursing examples in hemorrhagic shock and multiple fractures of the thoracic and lumbar regions]. PMID- 6904611 TI - [Infections in multiple injuries--an observation on septicemia as the final stage]. PMID- 6904612 TI - [Critical care in multiple injuries--a case of multiple injuries with various complications. Clinical conference]. PMID- 6904613 TI - [Science of symptomatology: spasms. Physiopathology of motor function disorders]. PMID- 6904614 TI - [Science of symptomatology: spasms. The mechanism of voluntary movements and their disorders]. PMID- 6904615 TI - [Science of symptomatology: spasms. Nursing of patients with spasms in the department of neurosurgery--care from the time of hospitalization to discharge]. PMID- 6904616 TI - [Science of symptomatology: spasms. Infantile epilepsy and innovation in chronic care--a design of a class for the parents]. PMID- 6904617 TI - [10 problems with nasogastric tubes and how to solve them]. PMID- 6904619 TI - [Nursing of patients with anorexia nervosa]. PMID- 6904618 TI - [Participation by patients with nervous system diseases and their families in the therapeutic actions and health instructions to be given at the time of hospital discharge]. PMID- 6904620 TI - [Various problems concerning decubitus ulcer]. PMID- 6904621 TI - [Bedside guidance in cardiology. 4. Vital signs]. PMID- 6904622 TI - [New sequence in orthopedic nursing. 3. Congenital hip dislocation--diapering for prevention and therapy]. PMID- 6904623 TI - [The goal of the nursing course leading toward a nursing degree: assistance in developing a positive attitude in learning]. PMID- 6904624 TI - [Selection of teaching materials and a format of models: a plan in adult nursing study. (2)]. PMID- 6904625 TI - [Teaching in clinical training in anatomy]. PMID- 6904626 TI - [Significance of establishment of a course leading to a master's degree in nursing]. PMID- 6904628 TI - [Attitudes of students at a nursing college: at the Noto Public General Hospital School of Nursing]. PMID- 6904627 TI - [Record of clinical training in pediatric nursing: planning of the course with the nursing record as its basis. (2)]. PMID- 6904630 TI - [Scene with illness--11. The question of informing the patient with cancer of the true nature of his illness]. PMID- 6904629 TI - [Nurse's record in caring for her mother who suffers from cancer]. PMID- 6904631 TI - [Guidelines for nursing instructors]. PMID- 6904632 TI - [Report by a chief nursing instructor. 1. Slow but steady progress in nursing education]. PMID- 6904633 TI - [Report by a chief nursing instructor. 2. Focus on the process of intellectual and psychological development of the nursing students]. PMID- 6904634 TI - [Report by a chief nursing instructor. 3. Nursing education designed and carried out by us]. PMID- 6904635 TI - [Record of clinical training in pediatric nursing: planning based on the nursing process record. (1)]. PMID- 6904636 TI - [A scene with illness. 9. A patient with brain death and the reactions of her family members]. PMID- 6904637 TI - [Human interactions and psychological struggles]. PMID- 6904638 TI - [Revitalization of public health clinic activities; a discussion]. PMID- 6904639 TI - [Revitalization of the public health clinic in the present crisis, with a critique on the "Study on Reorganization of the Regional Public Health Service Systems"]. PMID- 6904640 TI - [Allocation of public health nurses and the relationship between public health clinics and local municipalities. 2. Studies on the prefectural public health clinics]. PMID- 6904641 TI - [Schizophrenic mother and her infant: a public health nurse's experience]. PMID- 6904642 TI - [Social welfare of the aged]. PMID- 6904643 TI - [Regional nursing care of hypertension patients: patient welfare, the status of medical therapy and follow-up of patient dropouts]. PMID- 6904645 TI - [Public health activities based on daily life and labor: an evaluation of the activities in Shinano-machi (Nagano Prefecture) from the viewpoint of primary health care; a discussion]. PMID- 6904644 TI - [Problems of the aged reflected in hospitalization. I. A study of 4 examples within the jurisdiction of Chuo-ku Chuo Public Health Clinic]. PMID- 6904646 TI - [Organization of the Shinano-machi Health Study Group from the viewpoint of primary health care and the evaluation of its function]. PMID- 6904647 TI - [Allocation of public health nurses in cities and special wards]. PMID- 6904648 TI - [3 years' experience in home nursing]. PMID- 6904649 TI - [Problems of the aged reflected in hospitalization. II. The utilization of hospitals and other facilities]. PMID- 6904650 TI - [Assistance to psychiatric patients at city public health clinics: the single person with psychiatric symptoms]. PMID- 6904651 TI - The marital sexual relationship during pregnancy. AB - Physical and psychological changes during pregnancy which affect sexual relationships are discussed. Some of these changes can cause a rift between husband and wife; however, the nurse can play a key role in helping couples successfully adjust to changing sexual relationship. Recommendations for counseling pregnant couples are given. PMID- 6904652 TI - Basics of breastfeeding. Part iii: the biological specificity of breast milk. PMID- 6904653 TI - Basics of breastfeeding. Part IV: Preparation for breastfeeding and early optimal functioning. PMID- 6904654 TI - Maternal position during labor and birth: a reassessment. AB - The traditional dorsal position for labor and birth is a relatively recent innovation, and distinct disadvantages have been cited. The lateral position and the upright position have been found to improve the quality of uterine contractions. The upright position, in addition, appears to result in shorter, more comfortable labors than the other positions. Women need to be educated as to the benefits of alternative positions and mobility and should be assisted to assume these more physiological postures during parturition. PMID- 6904655 TI - Postpartum sexuality. PMID- 6904656 TI - Sexual needs and concerns of expectant parents. AB - Pregnancy is a maturational crisis which involves changes in the sexually related roles and functions of an expectant couple. The needs and concerns of such couples regarding sexuality are often not readily communicated and are therefore potential contributors to marital stress. in order to assist prenatal instructors to deal with these needs a questionnaire was developed in three phases to elicit perceived needs from a total of 50 individuals. The needs elicited were categorized and subsequently directed the formulation of objectives for a prenatal teaching program. PMID- 6904657 TI - Sexual needs and interests of postpartum couples. AB - the birth of a child may cause difficulties in the sexual adjustment of a marital relationship. The informational interests of 42 postpartum couples were investigated. Results indicate that postpartum sexual counseling needs to be individualized and that nurses and health educators can make a significant contribution to the quality of nursing care given to patients. PMID- 6904659 TI - [Sudden infant death]. PMID- 6904658 TI - Contraception and adolescent pregnancy. AB - To identify reasons for increasing numbers of pregnant adolescents, questionnaires were distributed to teenagers with unplanned pregnancies to determine the level of their knowledge of contraception. Findings revealed that 94% of the subjects had an adequate knowledge of availability, while only 43% had an adequate overall knowledge of contraception. Subjects reported many misconceptions about contraceptives and a general lack of motivation concerning contraceptive use. PMID- 6904660 TI - [A visit to the Midwives' Institute which has undergone a thorough renovation]. PMID- 6904662 TI - [Care and adoption of children]. PMID- 6904661 TI - [Statement by the Parents' Council course]. PMID- 6904664 TI - [Rheumatoid arthritis and LED as pregnancy complications]. PMID- 6904663 TI - [Hypophyseal tumors]. PMID- 6904665 TI - [Pregnancy monitoring by observation of fetal movements]. PMID- 6904667 TI - [Sexuality in aged patients: a report from a hospital for the aged. 9]. PMID- 6904666 TI - [How can family prophylaxis be further promoted?]. PMID- 6904668 TI - [Profile of a nurse: Mardiyah Harun, a student studying in Japan on a Japan Indonesia Exchange Project]. PMID- 6904670 TI - [Medical topics. Chinese restaurant syndrome]. PMID- 6904669 TI - [Medical topics. Beta-endorphin and delivery]. PMID- 6904671 TI - [Imagination in nursing: sensitivity and sensibleness in nursing]. PMID- 6904672 TI - [Primary health care - a pressing current problem]. PMID- 6904673 TI - [Nursing education and nursing schools]. PMID- 6904674 TI - [Imagination in nursing: imagination expected in the nursing group]. PMID- 6904675 TI - [Imagination in nursing: understanding of the patient from the circumstances - imagination in the process of cognition]. PMID- 6904676 TI - [Imagination in nursing: perceptiveness in nursing]. PMID- 6904678 TI - [The 2nd Symposium of the Tokyo Home Care Research Organization: obstacles in continued nursing]. PMID- 6904677 TI - [Presidential address: toward establishment of a stronger organization]. PMID- 6904679 TI - [An observation on the content of the course on adult nursing]. PMID- 6904680 TI - Functions of the Kansas State Board of Nursing. PMID- 6904682 TI - Continuing education: myths and facts. PMID- 6904681 TI - Temporary nursing service benefits employer and employee. PMID- 6904683 TI - Speaking out on politics. PMID- 6904684 TI - Ethics: codes or no codes? PMID- 6904685 TI - Emergency: code blue. Interview by Kathy Busch. PMID- 6904686 TI - Ethics: blowing the whistle while you work. PMID- 6904687 TI - Advanced nursing programs: an overview of Wichita State University. PMID- 6904688 TI - The who, what, when, why and how of professional negotiations for nurses. PMID- 6904690 TI - [Chronic hepatitis: pathogenesis, clinical aspects and therapy]. PMID- 6904689 TI - Principles & policies of collective bargaining of KNA. PMID- 6904691 TI - [Alcoholism and road traffic]. PMID- 6904692 TI - [Many factors lead to carcinoma]. PMID- 6904693 TI - [There is something lacking in education and professional loyalty]. PMID- 6904694 TI - [What does it mean "really dead"?]. PMID- 6904695 TI - [Malignant melanoma]. PMID- 6904696 TI - [Current methods in performance analysis]. PMID- 6904697 TI - [Non-nursing tasks skim off manpower. Shortage of nursing personnel endangers humanization]. PMID- 6904698 TI - [Working place underneath the geysers]. PMID- 6904699 TI - Adolescent perceptions of the school nurse. PMID- 6904700 TI - Belief assessment as a component of curriculum planning: cigarette smoking as an example. PMID- 6904701 TI - The effects of school sex education programs: a review of the literature. PMID- 6904702 TI - Evaluation of a respiratory health education program. PMID- 6904703 TI - The health educator as death educator: professional preparation and quality control. PMID- 6904704 TI - The effects of educational intervention & parental support on dental health. PMID- 6904705 TI - Early school health: an analysis of its impact on primary care. PMID- 6904706 TI - Stinky. PMID- 6904708 TI - School nurses as change agents: controlling our destiny. PMID- 6904707 TI - Health educator preparation via other disciplines? PMID- 6904709 TI - [Geriatric nursing and nursing education: a basic understanding of gerontology is expected in geriatric nursing]. PMID- 6904710 TI - [Geriatric nursing and nursing education. The diversity of problems in geriatric nursing and the response of nursing education]. PMID- 6904711 TI - [Geriatric nursing and nursing education. The position of geriatric nursing in the nursing course]. PMID- 6904713 TI - [Geriatric nursing and nursing education. The welfare problems of the aged and public health nursing education]. PMID- 6904712 TI - [Geriatric nursing and nursing education. Home nursing of aged patients in the basic nursing course program]. PMID- 6904714 TI - Changes in time perception at different times of day: toward a better understanding of the patient's perception of time. PMID- 6904715 TI - [Living nursing, an essay on nursing philosophy]. PMID- 6904716 TI - [Human science. Sex. 1. The sex behaviors of animals]. PMID- 6904717 TI - [Bedside conference in pediatric nursing. 10. The nursing of children with respiratory diseases (No. 3), neurologic diseases (No. 2), malignant neoplasms (No. 3), hematologic diseases (No. 5) and kidney]. PMID- 6904718 TI - [Focal points in nursing education. 7. The definition of the curriculum]. PMID- 6904719 TI - [Curriculum evaluation: theory and practice; with a case study from nursing education. 1]. PMID- 6904721 TI - [Nursing and self care: definition of self care]. PMID- 6904720 TI - [Study of the learning process in establishing a nursing philosophy]. PMID- 6904722 TI - [Nursing and self care: patient education at the time of discharge for more effective self care]. PMID- 6904723 TI - [Nursing and self care: continued nursing and self care by the patient]. PMID- 6904724 TI - [Nursing and self care: rehabilitation and self care--an evaluation of ADL]. PMID- 6904725 TI - [Nursing and self care: regional activities to aid self care of the aged]. PMID- 6904726 TI - [Psychology of the wife who is facing her husband's death and the role of nursing]. PMID- 6904727 TI - [Life science. 6. Life science and the road to creation of new universal civilization]. PMID- 6904728 TI - [Bedside conference in pediatric nursing. 9. Nursing and hepatic, respiratory, and circulatory diseases of children]. PMID- 6904729 TI - [Primary health nursing in England. 6. The reorganized National Health Service 1974]. PMID- 6904730 TI - [A focal point in nursing education. 6. Nursing education as a professional education]. PMID- 6904731 TI - [Teacher/student relationships: perspectives in clinical teaching]. PMID- 6904732 TI - [A trial in problem-solving learning process by groups--for establishing active learning attitudes]. PMID- 6904733 TI - [Nursing process: nursing of patients with lung cancer. Description of lung cancer]. PMID- 6904734 TI - [Nursing process: nursing of patients with lung cancer. Diagnosis and treatment of lung cancer--keypoints based on histological type and clinical course]. PMID- 6904735 TI - [Nursing process: nursing of patients with lung cancer. Nursing process and patients with lung cancer--medical history and information about the patients and practice and evaluation of the nursing care]. PMID- 6904736 TI - [Nursing process: nursing of patients with lung cancer. Evaluation of the nursing process: Discussion]. PMID- 6904737 TI - [Nursing and therapy: fluid infusion. Theory and methods of fluid infusion therapy]. PMID- 6904738 TI - [Nursing and therapy: fluid infusion. Nursing care associated with infusion therapy]. PMID- 6904739 TI - [Study in humane nursing: Assistance of a patient with ICU syndrome]. PMID- 6904740 TI - [Encounter of the patient and the medical personnel. (6). In psychiatric nursing]. PMID- 6904741 TI - [Nursing action associated with excretion and its re-evaluation--analysis of the nursing process designed for the patient being trained to use a bed pan prior to surgery]. PMID- 6904742 TI - Correlation between biochemical and morphological repair in rabbit lungs after elastase injury. PMID- 6904743 TI - [Sensitivity of Salmonella species to four "classical" antibiotics and seven new beta-lactamic antibiotics (author's transl)]. AB - A study of the minimal inhibitory concentration (MIC) for 200 strains of Salmonella sp. has been performed with the following beta-lactamic antibiotics: mezlocillin and azlocillin (penicillins), cephaclor, cephamandole, cephuroxime and cephotaxime (cephalosporins), and cephoxytine (cephamycin). The MIC has been compared with that of chloramphenicol, ampicillin, amoxicillin and cotrimoxazole, all of them widely used antibiotics for the treatment of Salmonella infections in Spain. The different species and serotypes of Salmonella studied were all sensitive to all the beta-lactamic antibiotics tested. Of particular relevance is the fact that cephotaxime (HR 756) MIC was extraordinarily low even for strains resistent to the penicillins. The MIC of cephaclor, and oral cephalosporin, was similar to that of the parenteral cephalosporins. PMID- 6904745 TI - The government's economic policies and the wage earner. PMID- 6904744 TI - A.C.T.U., guest speaker. PMID- 6904746 TI - Training aid in the Pacific and Asian Region. PMID- 6904747 TI - Occupational health and safety in hospitals. PMID- 6904748 TI - Law and the nurse. PMID- 6904750 TI - Technological change: issues and impacts. PMID- 6904749 TI - Uranium. PMID- 6904751 TI - The rights of patients. PMID- 6904752 TI - Fetal heart rate monitoring. PMID- 6904755 TI - Infectious tuberculosis. PMID- 6904753 TI - Stress. PMID- 6904754 TI - Summer camp for diabetic children. PMID- 6904757 TI - Nurse education--government policies. PMID- 6904756 TI - The adaption of principles to a variety of nursing care activities. PMID- 6904758 TI - Past, present and future - nursing education of NSW. PMID- 6904759 TI - Cabinet Decision on 'SAX'. PMID- 6904760 TI - Response to the Federal Government decision on the SAX Report. PMID- 6904761 TI - Teaching strategies. PMID- 6904763 TI - The death of Tuppence. PMID- 6904762 TI - New and changing technology: the laryngograph--new speech aid for deaf children. PMID- 6904765 TI - Nursing education in limbo. PMID- 6904764 TI - The social professionalisation of student nurses. PMID- 6904767 TI - [Work experience of a children's preschool institution in protecting children's health]. PMID- 6904766 TI - President's message: Nursing's decade of decision - the 1980's. PMID- 6904768 TI - [Morphological characteristics of the red blood indices of preschool children in the Arctic]. PMID- 6904769 TI - [Complex evaluation of the health status of schoolchildren]. PMID- 6904771 TI - [Food allergy in infants]. PMID- 6904770 TI - [Otoantritis in children]. PMID- 6904772 TI - [Angiographic method of x-ray diagnosis of diseases in pediatric practice]. PMID- 6904773 TI - [Pronunciation disorders in children]. PMID- 6904774 TI - [Observation of child growth and development in children's preschool institutions]. PMID- 6904775 TI - [From the 1st day of an infant's life]. PMID- 6904776 TI - [Standard of the nurse's work in neonatal wards]. PMID- 6904777 TI - [Control of enterobiasis in children's preschool institutions]. PMID- 6904778 TI - [Poisonings of children by water hemlock]. PMID- 6904779 TI - [Method of conducting the classes in an "Introduction to Specialties" course]. PMID- 6904781 TI - [Rack with trays for disinfecting surgical instruments]. PMID- 6904780 TI - [Utilization of advanced experience in the practical work of the head nurse in a provincial hospital]. PMID- 6904782 TI - [Joint work experience of public health and public education organs in health protection for children in preschool institutions]. PMID- 6904783 TI - [Keep children from accidents]. PMID- 6904784 TI - [Ways to improve the physical education of children in preschool institutions]. PMID- 6904785 TI - [Preparing children in kindergartens for school instruction]. PMID- 6904786 TI - The President's address: perspectives in nursing. PMID- 6904787 TI - Educator's corner: entry into practice information. PMID- 6904788 TI - First nurse-managed chronic disease clinic opens. PMID- 6904789 TI - ANA: a multipurpose, representative professional association. PMID- 6904792 TI - Obstetrical consequences of epidural analgesia in multiparous patients. PMID- 6904790 TI - First impressions: can interviewers pass the test? PMID- 6904791 TI - Prevention of arterial disease. PMID- 6904793 TI - Diet and primary prevention of coronary disease. PMID- 6904794 TI - Virus infections in pregnancy--with special reference to rubella. PMID- 6904795 TI - The causes of male and female infertility. PMID- 6904796 TI - Home birth--the Dutch and the English view. PMID- 6904797 TI - A child in the labour ward. PMID- 6904798 TI - Primary care nursing in the next five years. PMID- 6904799 TI - Staffing a regional neonatal unit. PMID- 6904800 TI - Organising a midwifery school library: guidelines for the non-librarian. PMID- 6904801 TI - Prepared childbirth and drugs--especially sparine. PMID- 6904802 TI - Perinatal mortality enquiries carried out at district level. PMID- 6904803 TI - Traditional midwives and family planning. PMID- 6904804 TI - Organising a midwifery school library : quidelines for the non-librarian. PMID- 6904805 TI - A question of statistics. PMID- 6904806 TI - Image: professional. Your authority to practice: your rights, your profession. PMID- 6904808 TI - Image: knowledge. Entry level. PMID- 6904807 TI - Image: leaders. Getting involved. Interview by Jackie Gideon. PMID- 6904809 TI - A composite profile of a drug troubled nurse. PMID- 6904810 TI - The nurse's role in a critical preventive issue (child auto safety). PMID- 6904812 TI - Writers' workshop for nurses. PMID- 6904811 TI - Insurance coverage of alcoholism treatment. PMID- 6904813 TI - The legal aspects of surgery. PMID- 6904814 TI - Functions of the operating room personnel. PMID- 6904815 TI - Theatre nursing care study: cystoscopy and trans-urethral resection of a bladder tumour. PMID- 6904816 TI - The role of the nurse in the anaesthetic room. PMID- 6904817 TI - A new look for AANNT. PMID- 6904819 TI - Innovative technique for peritoneal dialysis dressing. PMID- 6904818 TI - A view of self-care as seen by patients. PMID- 6904820 TI - Pitfalls of the helping person. PMID- 6904821 TI - Reducing job stress by open meetings. PMID- 6904822 TI - Corporate nurse: seek and you shall find. PMID- 6904823 TI - Coping with dietary emergencies for dialysis patients. PMID- 6904824 TI - Peritoneal dialysis--a nursing update. PMID- 6904825 TI - Ethics as a component of the curriculum. PMID- 6904826 TI - Supply and demand for registered nurses: some observations on the current picture and prospects to 1985. Part 2. PMID- 6904827 TI - Educational preparation for nursing--1979. PMID- 6904828 TI - Characteristics of the adult learner and extended higher education for registered nurses. PMID- 6904829 TI - Government regulation of testing in the offing? PMID- 6904830 TI - Care enough to compromise. PMID- 6904831 TI - Toward collaboration: one small step. PMID- 6904832 TI - Program evaluation: an overview. PMID- 6904833 TI - Quality assurance in public health. PMID- 6904834 TI - Strategic factors in hospital nursing practice. PMID- 6904835 TI - Power & politics for the nurse executive. PMID- 6904836 TI - Attracting and retaining more nursing students: developmental instruction for the non-traditional student may be one solution to the problem. PMID- 6904837 TI - Computation competency. PMID- 6904838 TI - Salaries in community health agencies--1980. Report of the annual study conducted by NLN's division of Home Health Agencies and Community Health Services. PMID- 6904839 TI - Ambulatory care nursing: at the crossroads? PMID- 6904840 TI - Educational strategies for teaching the elderly patient. PMID- 6904841 TI - Senior citizens centers offer learning opportunities. PMID- 6904842 TI - [The Law and the A.P.D. Synthesis of the legal regulations relative to the ATS APD]. PMID- 6904843 TI - [Nursing personnel in the rural area]. PMID- 6904844 TI - ["Health for today and in the year 2000", somewhat more than a slogan]. PMID- 6904845 TI - [Contribution of nursing to primary health care]. PMID- 6904846 TI - [What kind of health will the Spanish have? The concept of health care according to the Constitution and to health services reform]. PMID- 6904847 TI - [Health services' structure in Cuba. Experiences from the 1st Congress of the Cuban Nurses' Association]. PMID- 6904848 TI - [The General Council of Physicians publishes a booklet on its problems with the ATS]. PMID- 6904849 TI - [The ADP's opinion: descriptive report of a preliminary study done among the ATS APD's of the rural area]. PMID- 6904850 TI - Emerging legal responsibilities of nurses. PMID- 6904851 TI - Nurses, nursing and malpractice litigation: 1967-1977. PMID- 6904852 TI - On the scene: risk management in health care. PMID- 6904853 TI - Current legal issues facing nursing practice. PMID- 6904854 TI - The policy manual: a basis for legal protection. PMID- 6904855 TI - NAQ forum: nursing and the law. PMID- 6904856 TI - Legal considerations in nursing service. PMID- 6904857 TI - Liability for the negligence of hospital nursing personnel. PMID- 6904859 TI - A cross-cultural approach to integrating nursing theory and practice. PMID- 6904858 TI - A framework for analysis and evaluation of conceptual models of nursing. PMID- 6904860 TI - The role of staff development in hospital cost control. PMID- 6904861 TI - Selecting a doctoral program for a career in nursing. PMID- 6904862 TI - Toward effective and efficient use of the clinical laboratory. PMID- 6904863 TI - Teaching physiological assessment of black persons. PMID- 6904864 TI - The teaching of nursing research: a survey report. PMID- 6904865 TI - Smiling faces. PMID- 6904866 TI - Getting the best out of oxygen delivery systems. PMID- 6904867 TI - We played a game with Jill...and Jill won. PMID- 6904868 TI - The new urine meters. PMID- 6904869 TI - Cisplatin: a breakthrough for the cancer patient, a nursing challenge for you. PMID- 6904870 TI - Primary nursing. Part 2. PMID- 6904871 TI - 4 steps for helping a patient alleviate anger. PMID- 6904872 TI - Nursing update. Part 2. Caring for the catheter carefully...before, during, and after peritoneal dialysis. PMID- 6904873 TI - Teaching young patients--and their families--about home peritoneal dialysis. PMID- 6904875 TI - How do you rate as a nursing manager? PMID- 6904876 TI - The story of 5B could be your story, too. PMID- 6904877 TI - Combine your nursing and administrative skills as a nephrology nurse specialist. PMID- 6904874 TI - Medication errors: don't be misled by a number preceding a drug name. PMID- 6904878 TI - Working with a killer. PMID- 6904879 TI - Vantage point: associate degree nursing. PMID- 6904880 TI - Diagnostic tests: preparing your patient psychologically for an esophagogastroduodenoscopy. PMID- 6904881 TI - Cancer immunotherapy: what, why, when, how. PMID- 6904882 TI - The Swan-Ganz catheter: a program for teaching safe, effective use. PMID- 6904883 TI - The manipulative patient spells trouble. PMID- 6904884 TI - Gastric bypass for morbid obesity. Nursing grand rounds. PMID- 6904885 TI - You don't have to be an expert to give sexual counseling to a mastectomy patient. PMID- 6904886 TI - Test your knowledge of caring for the medical patient. PMID- 6904887 TI - Getting better urine specimens with the clean-catch midstream technique. PMID- 6904888 TI - The patient's representative: whose side is she on? PMID- 6904889 TI - Report on intravenous therapy national survey. PMID- 6904890 TI - Computing i.v. flow rates. PMID- 6904891 TI - Behavior therapy: introduction. PMID- 6904892 TI - Behavioural approaches. PMID- 6904894 TI - Phobias. PMID- 6904893 TI - Therapy without pills. PMID- 6904895 TI - Agree to live dangerously. PMID- 6904896 TI - The proof of the pudding. PMID- 6904897 TI - Child abuse: a behavioural approach. PMID- 6904898 TI - Token power. PMID- 6904899 TI - Retraining geriatric patients. PMID- 6904900 TI - A programme for the mentally handicapped. PMID- 6904902 TI - Sleep and comfort: introduction. PMID- 6904901 TI - Training the mentally handicapped at home. PMID- 6904903 TI - Sleep: its function and measurement. PMID- 6904904 TI - The concept of comfort and its measurement. PMID- 6904905 TI - Chair comfort for the elderly and infirm. PMID- 6904906 TI - Sleep and comfort during pregnancy and after birth. PMID- 6904908 TI - Pictures in nursing: silent night? PMID- 6904907 TI - A good night's sleep: the problems of children in hospital. PMID- 6904909 TI - Living with rheumatoid arthritis. PMID- 6904910 TI - Comfort for the chronic arthritic in hospital. PMID- 6904911 TI - Careers in nursing: caring for children with rheumatoid arthritis. PMID- 6904912 TI - Night sedation and sleep. PMID- 6904913 TI - Sleep, body rhythms and shiftwork. PMID- 6904914 TI - A scientific approach to nursing practice. PMID- 6904916 TI - QUANGOs on the way out. PMID- 6904915 TI - The primary health care team. PMID- 6904917 TI - Legal notes: Employment Act 1980, Industrial Tribunal 1980 Procedural Rules. PMID- 6904918 TI - Ergonomics: working in harmony with machines. PMID- 6904920 TI - Health education in the workplace. PMID- 6904919 TI - Hazards that fuelled industrial unrest: the background to the Polish strikes. PMID- 6904921 TI - Safety: attributing cause. PMID- 6904922 TI - Lead: preventing absorption. PMID- 6904923 TI - First aid: teaching the teacher. PMID- 6904924 TI - Continuing education and occupational health nursing: a value analysis. PMID- 6904925 TI - Self-directed continuing education. PMID- 6904926 TI - What's happening with mandatory CE? Mandatory CE--the status today. PMID- 6904927 TI - Developing a core series of continuing education for occupational health nurses. PMID- 6904928 TI - Certification in occupational health nursing. PMID- 6904929 TI - If you have it--flaunt it. PMID- 6904930 TI - A five-state regional educational experiment. PMID- 6904931 TI - Survey of interest in continuing education for occupational health nurses in Wisconsin. PMID- 6904932 TI - Mandatory vs. voluntary continuing education. PMID- 6904933 TI - The stress response. PMID- 6904934 TI - The holistic experience of stress: opportunity for growth or illness. PMID- 6904935 TI - Stress in the crisis experience: nursing interventions. PMID- 6904936 TI - A message from the President: implementation of the Association's Structure study. PMID- 6904937 TI - Stress: a useful concept for occupational health nursing. PMID- 6904938 TI - Alcohol education program: a benefit for you. PMID- 6904939 TI - A disaster experience. PMID- 6904940 TI - [Psychological guidance of patients with neoplastic diseases]. PMID- 6904941 TI - [Trends in rehabilitation of cervical cord injuries]. PMID- 6904942 TI - [The nursing process - a practical method for nursing activities]. PMID- 6904943 TI - [Inservice education for registered nursing personnel and assistant health personnel in LKH. Feldbach 1980]. PMID- 6904944 TI - [Assistance in disease and dying. Report on the 1st work week of this continued education course]. PMID- 6904945 TI - [Hallucinatory processes]. PMID- 6904946 TI - [Extract from the results of a group activity to be reported to Privy Councillor Dr. G. Weiser about "Problems in psychogeriatrics"]. PMID- 6904947 TI - [Problems in geriatric psychiatry]. PMID- 6904949 TI - [The relationship between patient and nurse]. PMID- 6904948 TI - [By log canoe through the tropical forest: an Upper Austrian nurse in the Peruvian lowlands]. PMID- 6904950 TI - [Nursing Day 1980. Role of nursing services in primary health care]. PMID- 6904951 TI - [Research in nursing]. PMID- 6904952 TI - [Social role playing as concrete professional preparation]. PMID- 6904953 TI - [Nursing - profession or vocation]. PMID- 6904954 TI - [Care of patients with laryngeal carcinoma. 1]. PMID- 6904955 TI - [How can you get rid of the smoking habit?]. PMID- 6904956 TI - Mothers' decisions about infant nutrition. PMID- 6904957 TI - Exercise, the asthmatic child and PL 94-142. PMID- 6904958 TI - Primigravidas' perceptions of early postpartum. PMID- 6904959 TI - Imaginary companions - friend or foe? PMID- 6904960 TI - Premature infant development: the relationship of neonatal stimulation, birth condition and home environment. PMID- 6904961 TI - Pediatric drug information: food allergies, food additives, and the Feingold diet. PMID- 6904962 TI - Pediatric management problems (tubal pregnancy). PMID- 6904964 TI - NLN nursing data book 1979: statistical information on nursing education and newly licensed nurses. PMID- 6904963 TI - Siblings need a plan of care, too. PMID- 6904965 TI - The National League for Nursing/American Public Health Association program for accreditation of home health agencies and community nursing services. PMID- 6904966 TI - Curriculum design for associate degree nursing programs: teaching and evaluation in the classroom. PMID- 6904967 TI - Curriculum design for associate degree nursing programs: factors in program direction. PMID- 6904968 TI - Scholarships, fellowships, educational grants and loans for registered nurses. PMID- 6904969 TI - Scholarships and loans for beginning education in nursing. PMID- 6904970 TI - Alterations in tRNA isoaccepting species during erythroid differentiation of the Friend leukemia cell. AB - The chromatographic profiles of isoaccepting tRNAs were analyzed at five time points during the 96 hr, dimethylsulfoxide induced, erythroid-like differentiation of Friend leukemia cells. Sixty-four isoaccepting species of tRNA for 16 amino acids were resolved by RPC-5 chromatography. The relative amounts of tRNAphe, tRNAile, and tRNAval species were maintained by the cells during differentiation; whereas the relative amounts of some of the isoacceptor tRNAs for the other 13 amino acids changed significantly. Fluctuations in amounts of isoacceptors occurred between 36 and 72 hr after addition of dimethysulfoxide, corresponding to globin mRNA appearance and hemoglobin synthesis, respectively. In most cases, thepredominant tRNA isoacceptors of uninduced cells were retained throughout differentiation. Notable exceptions were tRNA species for threonine, proline, and methionine. Some of the isoacceptors occurring in relatively smaller amounts were not expressed at all times. These changes possibly reflect the cell's functional adaptation of tRNA in differentiation for hemoglobin synthesis. PMID- 6904971 TI - Psychological and social care of 'stoma' patients. PMID- 6904972 TI - Slow motion suicide--the cigarette style. PMID- 6904973 TI - Breastfeeding: the natural option. PMID- 6904974 TI - Diabetes mellitus. PMID- 6904975 TI - Schizophrenia. PMID- 6904977 TI - An introduction to cardiovascular catheterisation and angiocardiography. PMID- 6904976 TI - Hypertension. PMID- 6904978 TI - The management of cardiac arrest in hospital. PMID- 6904979 TI - Priorities in health care delivery to the school child. PMID- 6904980 TI - The promotion of better understanding of mental illness. PMID- 6904981 TI - The battered child syndrome in Singapore. PMID- 6904982 TI - Biological and medical aspects of ageing. PMID- 6904983 TI - Social problems associated with ageing and the aged. PMID- 6904984 TI - The changing status of nursing as a profession in Japan. PMID- 6904985 TI - Social implications of mental illness. PMID- 6904986 TI - Teaching ethics by case analysis. PMID- 6904987 TI - The nursing staff organization: a needed development. PMID- 6904988 TI - Preparation for community health nursing: issues and problems. PMID- 6904990 TI - Competition vs cooperation in community health nursing. PMID- 6904989 TI - Outrageous or outraged: a nurse advocate story. PMID- 6904991 TI - Equal pay for comparable work. PMID- 6904992 TI - A developmental approach to the teaching of aging. PMID- 6904993 TI - Nursing process at the aggregate level. PMID- 6904994 TI - Demystifying the dissertation research proposal. PMID- 6904995 TI - Toward a partnership in learning. PMID- 6904996 TI - Stress variance in hospice nursing. PMID- 6904997 TI - Dalhousie University School of Nursing research and development fund. PMID- 6904998 TI - Relationships between classroom theory and clinical practice. PMID- 6905000 TI - Analysis of student performance ratings: a response. PMID- 6904999 TI - The development of a teaching module for nursing students on drug use information. PMID- 6905001 TI - Nursing: image in conversation. Interview by Shirley M. Stinson. PMID- 6905002 TI - The continuing challenge for nursing. PMID- 6905003 TI - Systems of life no. 71. Systems and signs: respiration-1. Inspection. PMID- 6905004 TI - Occupational stress among student nurses--2 A comparison of male and female wards. PMID- 6905005 TI - Nurse managers challenged. PMID- 6905006 TI - Points on the pattern. PMID- 6905007 TI - Nurses on the TA. PMID- 6905008 TI - Strange encounter. PMID- 6905009 TI - Nursing care study: a patient after cerebrovascular accident. PMID- 6905010 TI - Sexual activity following acute myocardial infarction in the male. PMID- 6905011 TI - The elderly and the district nurse. PMID- 6905012 TI - Recruitment--8. Filling the nursing schools. A question of cost and calibre. PMID- 6905013 TI - Suicide--do the Samaritans really help? PMID- 6905014 TI - Gently does it for a mixed-sex ward. PMID- 6905015 TI - Who's a lucky school nurse, then? PMID- 6905016 TI - The Rampton review. PMID- 6905018 TI - Mental handicap: Gwynedd answers the need. PMID- 6905017 TI - In at the beginning...highlights of the Health Visitors Association study conference. PMID- 6905019 TI - Garth Angharad--a hospital for mentally abnormal offenders. PMID- 6905020 TI - Community nursing with mentally handicapped adults. PMID- 6905021 TI - A community nursing service for mentally handicapped children. PMID- 6905022 TI - A patient with Stevens-Johnson syndrome. PMID- 6905023 TI - Improving nurses' managerial skills. PMID- 6905024 TI - Recruitment. Part 9. Wastage from nurse training. PMID- 6905025 TI - Ward scene. PMID- 6905026 TI - Hospitals should do the sick no harm. 11. Controlling infection by isolation--1. PMID- 6905027 TI - Obtaining student nurses--1. PMID- 6905028 TI - Ruled out. PMID- 6905029 TI - All part of the job. PMID- 6905030 TI - Death with dignity. PMID- 6905031 TI - Managing violent behaviour in a psychiatric ward: a psychiatric approach. PMID- 6905032 TI - A philosophy of patient care for the disturbed violent patient in a special hospital. PMID- 6905033 TI - Nursing care study: perforated gangrenous appendix. PMID- 6905034 TI - Recruitment--10. Adult learning and nurse education. PMID- 6905035 TI - X-ray anatomy 6. PMID- 6905036 TI - If treasurers took temperatures... PMID- 6905037 TI - Living and learning community. PMID- 6905038 TI - Nursing in Uganda. PMID- 6905039 TI - Glittering prizes. PMID- 6905040 TI - The catheter of choice. PMID- 6905041 TI - A nurse's guide to managing the patient with speech handicap following a stroke or head injury. PMID- 6905042 TI - Recruitment--11. Nurse employment and mobility of trained staff. PMID- 6905043 TI - Children in hospital. PMID- 6905044 TI - A school of children in hospital. PMID- 6905045 TI - Spotlight on children. Insights and images. PMID- 6905046 TI - Spotlight on children. Dilemma: a resident mother's view of intermittent long stay hospitalisation. PMID- 6905048 TI - Obtaining student nurses--2. Conclusions. PMID- 6905047 TI - Systems of life no. 72: systems and signs: respiration. 2. Palpation. PMID- 6905049 TI - A step closer to home. PMID- 6905050 TI - The fight for a health service in Poland. PMID- 6905051 TI - No one told me... preparing staff for leadership posts. PMID- 6905052 TI - Major implications. PMID- 6905053 TI - The basic management workshop. PMID- 6905054 TI - Site-based first-line management training. PMID- 6905055 TI - A course for sisters and charge nurses. The programme was tailored to meet the individual requirements of ward sisters. PMID- 6905056 TI - Nursing care study: myocardial infarction and some of the psychological factors involved. PMID- 6905057 TI - A nurse practitioner in Britain? PMID- 6905058 TI - Jungle nursing. PMID- 6905059 TI - Recruitment--12. Staffing community nursing services in London. PMID- 6905060 TI - The end of a dream? PMID- 6905061 TI - Floral arrangements. PMID- 6905062 TI - Is nursing research-based? PMID- 6905063 TI - Why I took up nursing. PMID- 6905064 TI - Modern times. PMID- 6905065 TI - Nursing care study: laparotomy, removal of trichobezoar and appendicectomy. PMID- 6905066 TI - Brain death. PMID- 6905067 TI - Fats and heart disease: points for controversy. PMID- 6905068 TI - Nurses and alcohol-related problems. PMID- 6905069 TI - Help for families of problem drinkers. PMID- 6905070 TI - Operation Drake--2. Sulawesi newsletter. PMID- 6905071 TI - Recruitment--13. Women, work and the part-time community nurse in London. PMID- 6905072 TI - Symposium on endocrine disorders. PMID- 6905073 TI - The hypothalamus and the pituitary gland: an overview. PMID- 6905074 TI - The nurse's role in hypothyroidism. PMID- 6905075 TI - Dysfunction of the adrenal gland: physiologic considerations and nursing problems. PMID- 6905076 TI - Nursing implications of selected pediatric endocrine problems. PMID- 6905077 TI - Symposium on fluid, electrolyte, and acid-base balance. PMID- 6905078 TI - Physiology of body fluids. PMID- 6905079 TI - Clinical problems of fluid balance. PMID- 6905080 TI - Clinical problems of electrolyte balance. PMID- 6905081 TI - Fluid and electrolyte balance in the patient with a myocardial infarction. PMID- 6905082 TI - The use of a model for hemodynamic balance to describe burn shock. PMID- 6905083 TI - Blood and component therapy. PMID- 6905084 TI - Accident and emergency units: accidents will happen. PMID- 6905085 TI - Accident and emergency units. Be prepared for anything! PMID- 6905086 TI - Accident and emergency units. 'Is it a heart attack'? PMID- 6905087 TI - Accident and emergency units. Extending a helping hand. PMID- 6905088 TI - Accident and emergency units. An uncertain diagnosis. PMID- 6905089 TI - Accident and emergency units. Teamwork--an essential part of A and E. PMID- 6905090 TI - Accident and emergency units. Sudden death. PMID- 6905091 TI - What did we do last time? PMID- 6905092 TI - Midwifery was calling me. PMID- 6905093 TI - Parasitology. 2. A telling tail. PMID- 6905094 TI - International Conference on Cancer Nursing. 3. A combined therapeutic approach. PMID- 6905095 TI - Orthopaedics. 5. One step at a time. PMID- 6905097 TI - A great conspiracy of silence? PMID- 6905096 TI - Nursing care study.--Portal vein thrombosis: a severe case of bleeding. PMID- 6905098 TI - Home, unsweet home. PMID- 6905099 TI - This time next year. PMID- 6905100 TI - Diary: one nurse's week. PMID- 6905101 TI - Fighting the system. PMID- 6905103 TI - Leg elevation: shake a leg! PMID- 6905102 TI - Behaviour therapy: when a foe becomes a friend. PMID- 6905104 TI - Parasitology 3: Worming their way round. PMID- 6905105 TI - Irritable bowel syndrome: getting to the guts of the matter. PMID- 6905106 TI - Painless puncturing. PMID- 6905107 TI - Nursing care study. Abdominal mass: a suspicious burst. PMID- 6905108 TI - The babes in the ward. PMID- 6905109 TI - From one Fellow to another, take better care. PMID- 6905110 TI - Diary: one nurse's week. PMID- 6905111 TI - Where did they go right? PMID- 6905112 TI - Puberty: not so sweet sixteen. PMID- 6905113 TI - Puberty: growing pains. PMID- 6905114 TI - Is nursing more of an art than a science? NM travel scholarship. PMID- 6905115 TI - Nursery nurse: mothers and children first! PMID- 6905117 TI - International Cancer Nursing Conference. 4. What the cancer nurse can do. PMID- 6905116 TI - Geriatrics: a step in the homeward direction. PMID- 6905118 TI - Parasitology. 4. It only happens at night. PMID- 6905119 TI - Allergies: silent sufferers. PMID- 6905120 TI - Microbiology. 4. Pasteur's cheese and wine party. PMID- 6905121 TI - Community nursing. Psychiatric nurses: look to the future. PMID- 6905122 TI - Nursing care study. Haematoma of scrotum: painful end to a party. PMID- 6905123 TI - Nursing care study. Cerebrovascular accident: narrowing down the cause. PMID- 6905124 TI - What happens now? PMID- 6905125 TI - Of worms, patients and nurses. PMID- 6905126 TI - Diary: one nurse's week. PMID- 6905127 TI - Is nursing more of an art than a science? NM travel scholarship. PMID- 6905128 TI - Psychiatric emergency clinic: in time of trouble. PMID- 6905129 TI - Occupational medicine: the price of progress. PMID- 6905130 TI - Parasitology, 5. A fluke of nature. PMID- 6905131 TI - International Cancer Nursing Conference, 5. The power of the folk healer. PMID- 6905133 TI - Towards a more secure future? PMID- 6905132 TI - Nursing care study. Mental handicap: left behind. PMID- 6905134 TI - A positive push for promotion. PMID- 6905135 TI - Weaning: on the bottle again. PMID- 6905136 TI - Midwifery training: midwives first - nurses second? PMID- 6905137 TI - Sociology: times, they're a-changing. PMID- 6905138 TI - Is nursing more of an art than a science? NM travel scholarship. PMID- 6905139 TI - Psychiatry. 2. Loosening the legal straitjacket. PMID- 6905140 TI - Pharmacology: dantrolene sodium. PMID- 6905141 TI - International Cancer Nursing Conference. 6. Information - a prescription for recovery? PMID- 6905142 TI - Nursing care study. Hypertension: what is to become of me? PMID- 6905143 TI - Centre of excellence? PMID- 6905144 TI - Nursing overseas. PMID- 6905145 TI - Nursing overseas. A harbour of hope. PMID- 6905146 TI - Nursing overseas: the sacred cows of east and west. PMID- 6905148 TI - Nursing overseas: Turkish delights? PMID- 6905147 TI - Nursing overseas: after the bullets... PMID- 6905149 TI - Nursing overseas: no nurse is an island. PMID- 6905150 TI - Junk food: carving up the Third World. PMID- 6905151 TI - Is nursing more of an art than a science? NM travel scholarship. PMID- 6905152 TI - Chemotherapy related nausea and vomiting: a survey to identify problems and interventions. PMID- 6905153 TI - The development of a child's concept of death. PMID- 6905154 TI - An elective course in hospice nursing. PMID- 6905155 TI - Organizing cancer inpatient care. I. A scattered-bed model for cancer inpatient care. PMID- 6905156 TI - Organizing cancer inpatient care: scattered-bed versus oncology unit approach. PMID- 6905157 TI - Organizing cancer inpatient care. II. The specialty unit approach to cancer care. PMID- 6905158 TI - How to use methadone. A handbook for patients and families. PMID- 6905159 TI - Who will represent the members? PMID- 6905160 TI - President's message. PMID- 6905161 TI - The role of the legal system in the cesarean childbirth controversy. PMID- 6905162 TI - Enforcing professional standards. PMID- 6905163 TI - How to find the law. PMID- 6905164 TI - Moral integrity for nurses. PMID- 6905165 TI - Transfer trauma and the courts. PMID- 6905166 TI - Confidentiality - the psychotherapist's nemesis. PMID- 6905167 TI - [The ever dangerous carbon monoxide]. PMID- 6905168 TI - [Discussion]. PMID- 6905170 TI - [Practical exercises in a nursing school]. PMID- 6905169 TI - [Graduates of a nursing school]. PMID- 6905171 TI - [Personality of a teacher]. PMID- 6905172 TI - [The nursing report]. PMID- 6905173 TI - [Current classification of the clinical forms of heart disease]. PMID- 6905174 TI - [New graduates of the Medical Academy in Poznan]. PMID- 6905176 TI - [Problems of our profession]. PMID- 6905175 TI - [Health spa treatment of drug abuse]. PMID- 6905177 TI - [Between the nursing school and the hospital]. PMID- 6905178 TI - [In the service of one's own profession. Interview by Zofia Kalinowa]. PMID- 6905179 TI - [The hemophilias]. PMID- 6905180 TI - [Systems of nursing concepts]. PMID- 6905182 TI - [Preventive medicine]. PMID- 6905181 TI - [Discussion]. PMID- 6905183 TI - [Paper work in a ward]. PMID- 6905184 TI - [Quality of nursing care]. PMID- 6905185 TI - [Infectious diseases in Poland in 1970-1979]. PMID- 6905186 TI - [Student's conference]. PMID- 6905187 TI - [Plasmapheresis and its various forms]. PMID- 6905188 TI - [The Polanica spa]. PMID- 6905189 TI - [Invasive diseases]. PMID- 6905190 TI - [Male sterility - its causes and diagnosis]. PMID- 6905191 TI - [The level of our work]. PMID- 6905192 TI - [Protection of social health--in the light of the 3d session of the Polish Communist Party]. PMID- 6905193 TI - [Selection of medical students]. PMID- 6905194 TI - [The aged and their environment]. PMID- 6905195 TI - [The professional way of life]. PMID- 6905196 TI - [The role of nutrition in the etiology of neoplasms]. PMID- 6905197 TI - [Terminal care]. PMID- 6905198 TI - [The "Syrena" sanatorium]. PMID- 6905199 TI - [Is aspirin all that safe after all?]. PMID- 6905200 TI - [Pregnancy and various properties of semen]. PMID- 6905201 TI - [Problems of the 3d age]. PMID- 6905202 TI - Malignant lymphoma: an update on diagnosis, staging, and management. AB - The diagnosis of malignant lymphoma is not difficult. The various subtypes of Hodgkin's disease are easily recognized by the pathologist. The non-Hodgkin's lymphomas can be distinguished from Hodgkin's disease but are more difficult to classify. Staging of the lymphomas has improved. Computerized axial tomography and ultrasonography have assisted in the evaluation of the abdomen. Laparotomy and splenectomy continues to be a useful procedure for the pathologic staging of Hodgkin's disease, but its value will require yearly reassessment as improvements in staging and management are made. The treatment of Hodgkin's disease has been very successful. The majority of patients can be cured of the disease. Therapy has not had a major impact on survival of patients with nodular lymphomas, but has considerably improved the prognosis of patients with diffuse lymphomas. PMID- 6905203 TI - Disseminated intravascular coagulation: diagnostic and therapeutic considerations. AB - Disseminated intravascular coagulation, although an uncommon diagnosis on a general medical service, is one of the most common, acquired disorders of coagulation. With more aggressive therapy of critically ill patients it is also a diagnosis which is increasing in frequency. Recent advances in our understanding of the underlying causes for DIC and its pathophysiology have led to the establishment of diagnostic criteria and guidelines for the management of patients. Hemorrhage and thrombosis are the major criteria for initiation of therapy, and heparin is the most efficacious approach when correction of underlying causes is inadequate. Frequent monitoring of patients on heparin therapy can improve the benefit-to-risk ratio for this disorder. PMID- 6905204 TI - Idiopathic thrombocytopenic purpura. AB - The finding of thrombocytopenia with normal or increased megakaryocytes on bone marrow aspirate supports the diagnosis of ITP. It is essential, however, that every effort be made to exclude other causes of the consumption of platelets. Most cases of chronic ITP are immune in origin; consequently, steroid therapy is the initial treatment of choice, followed by splenectomy if indicated. Twenty five per cent of patients fail to respond to either treatment modality; however, bleeding manifestations are often mild even when a response in the platelet count is not achieved. Although acute ITP is often self-limiting, exacerbations and remissions may occur in both acute and chronic types of ITP. PMID- 6905205 TI - Screening for abnormal hemoglobins: who, when, and how. AB - Sickle cell and abnormal hemoglobin screening programs should not be undertaken lightly but rather should have a specific purpose or purposes. If the aim is to detect only sickle hemoglobin, a certain strategy is necessary. If the goal is to detect all abnormal hemoglobins and genetic counseling is planned, another approach should be used. A simple solubility test detects sickle hemoglobin with high reliability, but deals with no other abnormal hemoglobins. Hemoglobin electrophoresis, followed by other tests as indicated, is then necessary to ascertain other abnormal hemoglobins in addition to hemoglobin S. PMID- 6905206 TI - The evaluation of peripheral lymphadenopathy. AB - Lymph node enlargement occurs in a large variety of diseases, which may be considered in groups defined by their characteristic presentations. A meticulous history and physical examination will generally define the disorder, which may then be confirmed by appropriate laboratory procedures. Biopsy of the node is generally the last step in the diagnostic algorithm and is definitive in 40 to 60 per cent of cases. For the hard, nontender, unilateral cervical node, a meticulous search for the primary lesion should precede the biopsy. Continued observation and occasionally reevaluation are important aspects of the care of all patients. PMID- 6905207 TI - Anemia in infancy and childhood. AB - The definition, clinical manifestations, and causes of anemia in childhood are age-related and reflect the dynamic processes of growth and development during this period. Although the possible causes of anemia in children are extensive, the etiology is usually unifactorial. Thus, systematic evaluation of the anemia will usually result in the diagnosis of a specific anemia, which can then be effectively treated in a gratifying number of children. PMID- 6905208 TI - Polycythemia vera: clinical features, differential diagnosis, and treatment. PMID- 6905209 TI - Inherited and acquired bleeding disorders. PMID- 6905210 TI - The etiquette of primary care. PMID- 6905211 TI - Doctors' orders and nursing judgment. PMID- 6905212 TI - Discrimination against females in hospitals. Case in point: Watson v. Magee Women's Hospital (472 F. Supp. 325 - PA.). PMID- 6905213 TI - Legal briefs for nurses. S.C.: nurse nicked sciatic nerve. CA.: nursing in bedfall suit. PMID- 6905214 TI - Bizarre bedside behavior: employee fired! Case in point: Mitchell v. State (153 Cal. Prtr 552 - CA.). PMID- 6905215 TI - R.N. legal rights: right to complain. PMID- 6905216 TI - Nursing service director fights M.D.: loses! Case in point: Daley v. St. Agnes Hospital (490 F. Supp. 1309 - PA). PMID- 6905217 TI - Legal case briefs for nurses: N.Y.: R.N. ignored M.D. orders: malpractice. PA: ICU nurses: vital signs overlooked. PMID- 6905218 TI - Nursing supervision: reporting errant M.D.'s. PMID- 6905219 TI - Narcotics security: nursing policy. Case in point: Sapp v. Fla. State Board of Nursing (384 So. 2d 254 - FLA.). PMID- 6905220 TI - Legal briefs for nurses. IL: OBS: infant's brain damaged. GA: blood sampling: radial nerve injury. PMID- 6905221 TI - Post-op infection: poor nursing records. Case in point: St. Paul v. Prothro (590 S.W. 2d 35 - ARK.). PMID- 6905222 TI - Telephone orders: legally risky. PMID- 6905223 TI - Breast cancer - MD/RN malpractice: 185,000 dollars! Case in point: Truan v. Smith (578 S.W.2d 73 - TN). PMID- 6905224 TI - Clinical nursing. Delivery room privacy: R.N. responsibility. Case in point: Knight v. Penobscot Bay Med. Ctr (420 A. 2d 915 - ME). PMID- 6905225 TI - [Shock]. PMID- 6905226 TI - [A plan of action for improving the quality of health care]. PMID- 6905227 TI - [Social security I]. PMID- 6905228 TI - [Humanistic reflexion on nursing education]. PMID- 6905229 TI - [Use of radioisotopes for functional studies in medicine]. PMID- 6905230 TI - [Schizophrenia]. PMID- 6905231 TI - [The scope of activities of psychiatric nursing]. PMID- 6905232 TI - [Daily nursing care in psychiatry]. PMID- 6905233 TI - [Mental health services between the goat and the cabbage]. PMID- 6905234 TI - [Pediatric psychiatric nursing]. PMID- 6905235 TI - [We love them like children and respect them as human beings]. PMID- 6905236 TI - [Education of psychiatric nurses. Summary of regulations]. PMID- 6905237 TI - Sex Q and A. Frank answers to your most delicate patient-counseling questions. PMID- 6905238 TI - Caring for the patient--instead of the ventilator. PMID- 6905239 TI - Is it right? To turn off life support? To keep a body alive for its organs? To give illegal narcotics to the dying? PMID- 6905240 TI - Cancer chemotherapy. 4. Those dreaded side effects and what to do about them. PMID- 6905241 TI - Head off compartment syndrome before it's too late. PMID- 6905242 TI - Dysrhythmia of the month club: which patient is in greater danger? PMID- 6905243 TI - Indochina moves to main street: little refugees with big needs. PMID- 6905244 TI - Thoracentesis...and pericardiocentesis, too: your guide to proper prep. PMID- 6905245 TI - 'Last-ditch' heart assist is producing survivors. PMID- 6905246 TI - The drug interactions we all overlook. PMID- 6905247 TI - Legally speaking: pulling the plug isn't easy--explaining it is even harder. PMID- 6905249 TI - Aides need a little aid--from RN's. PMID- 6905248 TI - Patient education: RN's do it better than MD's. PMID- 6905250 TI - If you can't beat 'em... PMID- 6905251 TI - Minimal competence isn't even that: it's a fraud. PMID- 6905253 TI - Getting fed up? If so, some of these problems may ring a bell. PMID- 6905252 TI - Sex Q and A: frank answers to your most delicate patient counseling questions. PMID- 6905254 TI - How post-op complications can burgeon into crisis. PMID- 6905255 TI - Tips for your fractured-jaw patient. PMID- 6905257 TI - Spinal and peritoneal taps. When quick action counts. PMID- 6905256 TI - Indochina moves to Main Street: how to get through to a refugee patient. PMID- 6905258 TI - Bundle branch blocks: when to sound the alarm. PMID- 6905259 TI - Can self-hypnosis conquer stress? PMID- 6905260 TI - Drug therapy today: latest thinking on drug therapy post-MI. PMID- 6905261 TI - Legally speaking: you don't have to tolerate substandard hospital practices. PMID- 6905263 TI - Hall Commission: expanded nurses' role supported. PMID- 6905262 TI - RNABC casebook: who's right? PMID- 6905264 TI - Government subsidies: refresher courses to ease shortages. PMID- 6905265 TI - Puppets help nurses play pediatric role. PMID- 6905266 TI - The nurse shortage: no easy answers. PMID- 6905267 TI - Plasma prekallikrein (Fletcher factor) deficiency in a patient with chronic lymphocytic leukemia. AB - We have described the first patient to be reported in whom plasma prekallikrein (Fletcher factor) deficiency and chronic lymphocytic leukemia were both present. This most likely represents a coincidental occurrence, but the markedly elevated peripheral blood lymphocyte count and the detection of the defect using ellagic acid are unique for Fletcher factor deficiency. PMID- 6905268 TI - Proposed lay midwifery regulations. PMID- 6905270 TI - The status of nursing in South Carolina, 1980. PMID- 6905269 TI - The law and your practice. Liability for nurses. PMID- 6905271 TI - The influence of prejudice on women and nursing. PMID- 6905272 TI - The nursing shortage in state government. PMID- 6905273 TI - The law and your practice. Nurses in the work place. PMID- 6905274 TI - Professionals and collective bargaining. The art and science of supervision. PMID- 6905275 TI - Supervisors' rating of baccalaureate nurse competencies. PMID- 6905276 TI - A classification system for RN's. PMID- 6905277 TI - Developing a framework for inservice. PMID- 6905278 TI - Nursing's management crisis. PMID- 6905279 TI - Decentralizing nursing service--six months later. PMID- 6905280 TI - Cross-training program for nurses: a solution to a staffing problem. PMID- 6905281 TI - Enough of reality shock, burnout, and identity crisis! PMID- 6905282 TI - You who touch me in your passing. PMID- 6905283 TI - Terminally ill patient's right to refuse treatment. Law for the nurse supervisor. PMID- 6905284 TI - P.H.N. as interested person. Law for the nurse supervisor. PMID- 6905285 TI - An in-depth study of the head nurse role. PMID- 6905286 TI - The nurse internship question revisited. PMID- 6905287 TI - A quality assurance program for psychiatric nursing. PMID- 6905288 TI - Puppets in the nursing process. PMID- 6905289 TI - The photographic image process. PMID- 6905290 TI - The age of egocentrism: the art & science of supervision. PMID- 6905291 TI - Professional collegiality. PMID- 6905292 TI - A new beginning. The art & science of supervision. PMID- 6905293 TI - Research: will it help us come to age as a profession? PMID- 6905294 TI - Patient education & the audit. PMID- 6905295 TI - The role of the patient education coordinator. PMID- 6905296 TI - A comparative study of an infusion pump. PMID- 6905297 TI - Relating to the angry and withdrawn employee. PMID- 6905298 TI - Use supervisory personnel to recruit nurses! PMID- 6905299 TI - The influence of formal & informal organization within a modern hospital. PMID- 6905300 TI - Strategies for nurse-patient communication. PMID- 6905302 TI - The art and science of supervision: leadership and sex. PMID- 6905301 TI - Sticks and stones and broken bones. PMID- 6905304 TI - Identifying problems in a hospital nursing staff. PMID- 6905303 TI - Drug abuse among nurses: what nursing management can do! PMID- 6905305 TI - Meetings can improve nurse-doctor relations. PMID- 6905306 TI - Nurse internship program based on nursing process. PMID- 6905307 TI - The incident report as a risk management tool. PMID- 6905308 TI - The nurse administrator: a long distance runner. PMID- 6905310 TI - Effective management. PMID- 6905309 TI - Planning inservice education in small hospitals. PMID- 6905311 TI - [Team work out of a district college: religious communication and therapeutic consequences]. PMID- 6905312 TI - [Decentralized administration education]. PMID- 6905313 TI - [Nursing in the balance!]. PMID- 6905314 TI - [Specialty nurses - a necessity]. PMID- 6905315 TI - [Care of teeth and dental prostheses in homes for the aged and nursing homes]. PMID- 6905316 TI - [Report on suicide in the aged: it has no purpose]. PMID- 6905317 TI - [It has no purpose. Other part of an excerpt from the book on suicide in the aged]. PMID- 6905318 TI - [Ostfold study: where do student nurses want to work?]. PMID- 6905319 TI - [Future nursing education]. PMID- 6905320 TI - [Administration and leadership in the health sector]. PMID- 6905321 TI - [Nursing education reorganization in focus again]. PMID- 6905322 TI - [From the Blom Committee proposal: nursing services in Reitgjerdet]. PMID- 6905323 TI - [Information to heart patients]. PMID- 6905324 TI - [Occupational nurses' internal cooperation]. PMID- 6905325 TI - [Development of continued education in nursing]. PMID- 6905326 TI - [Recommendation on the need for a medication unit in the hospital]. PMID- 6905327 TI - [Project-oriented education and participant guidance]. PMID- 6905328 TI - [Professionalization or cooperation in district health services?]. PMID- 6905329 TI - [Nurses and wages]. PMID- 6905330 TI - [24-hour schedule planning in hospital and nursing home]. PMID- 6905331 TI - [Who will now lead Norwegian nursing?]. PMID- 6905332 TI - [Title headache: are midwives and health nurses vanishing?]. PMID- 6905333 TI - [What is the International Council of Nurses?]. PMID- 6905334 TI - [Team work: permanent parents' need for information]. PMID- 6905336 TI - [Illnesses spread among Norwegian nurses]. PMID- 6905335 TI - [Psychiatric nursing education in Iceland]. PMID- 6905337 TI - [District health services--leadership and team work]. PMID- 6905338 TI - [Ostfold made a study: old age and nursing homes could be used more efficiently]. PMID- 6905339 TI - [Reflection in Finland: 1000 new positions in the hospital sector per year]. PMID- 6905340 TI - [Deacon home hospital trial: new comprehensive care model for long-term patients]. PMID- 6905341 TI - [Professorosis and its spread in Norway]. PMID- 6905342 TI - [District health services in focus]. PMID- 6905343 TI - [Unpaid work is also work: care for the aged and the aged's concern. Interview by Sverre Rostol]. PMID- 6905344 TI - [Operating room nursing and nurse's role]. PMID- 6905345 TI - [Digitalis in heart diseases: American professor warns against overdose]. PMID- 6905346 TI - [Sudden unexpected infant death]. PMID- 6905347 TI - [Collective hospital management?]. PMID- 6905348 TI - [Future nursing education]. PMID- 6905349 TI - [5 reasons to select district colleges]. PMID- 6905350 TI - ["Community medicine" a new specialty?]. PMID- 6905351 TI - [Cytostatics as a residue risk]. PMID- 6905352 TI - [Quality as a recruitment factor]. PMID- 6905353 TI - [Inservice education--a Danish example]. PMID- 6905354 TI - [Experience from Oslo: cross-professional team work necessary in the health sector]. PMID- 6905356 TI - [Midwifery education in North Norway]. PMID- 6905355 TI - [Mother's milk is best]. PMID- 6905357 TI - [Nursing home--an educational working place]. PMID- 6905358 TI - [Social care in the Radium Hospital: patient's evaluation of new venture]. PMID- 6905359 TI - [Nurses sent out into the desolate territory of Turkana, Kenya: with responsibility for everything and competence in everything one does]. PMID- 6905360 TI - [Celiac patients must stick to their diet the rest of their lives]. PMID- 6905361 TI - [Do politicians have responsibility but no power?]. PMID- 6905362 TI - [The situation in Copenhagen's District Hospital in Ballerup: changed status adds to need for more personnel]. PMID- 6905363 TI - [From the Executive meeting 10 and 11 June 1980: acting out of spite with nurses' employment foundation]. PMID- 6905364 TI - [This is the way to help toward a dignified dying process and death]. PMID- 6905365 TI - [On nurses appointed as medical officers: a number of tasks where it is an advantage to employ nurses]. PMID- 6905366 TI - [The question is not whether it is superior or inferior]. PMID- 6905367 TI - [Reorganization of county health nurses' arrangement professionally the best]. PMID- 6905368 TI - [Drug information: agents for the treatment of cardiac arrhythmias. 5. (2) Arrhythmias relieved by changed impulse conduction/changed cellular reaction pattern]. PMID- 6905369 TI - [Commencement in Denmark's Nursing College in Arhus and Copenhagen: tell what we can do that emergency solutions cannot]. PMID- 6905370 TI - [Health nurses' work with the "pregnant family": health nurses must listen and discuss current problems]. PMID- 6905371 TI - [Getting ideas and inspiration for the benefit of the profession]. PMID- 6905372 TI - [Student nurse who made a study trip to Kenya: important to maintain structures in developing countries]. PMID- 6905373 TI - [Day care arrangement will be a good supplement to policies for the aged]. PMID- 6905374 TI - [Municipal Course Evaluation Council: will ensure a more simple and equal procedural treatment]. PMID- 6905375 TI - [Who will manage research studies?]. PMID- 6905376 TI - [Retraining course for inactive nurses in Hvidovre Hospital: large profits and nearly no expenses]. PMID- 6905377 TI - [Dagny Olausen, group leader. Participant in the 1977 retraining course held in Hvidovre Hospital: I have been incredibly fortunate]. PMID- 6905378 TI - [Ulla Andersen, participant in the 1979 retraining course held in Hvidovre Hospital: I was sold on it by the first evening already]. PMID- 6905380 TI - [Ritt Bjerregaard's inadequate insight into nurse-patient relations]. PMID- 6905379 TI - [FTF's representative in the Equality Council, Eva Munck: the supply of day care provisions must increase. Interview by Steffen Dalsgaard]. PMID- 6905381 TI - [Increasing demand for urinary condoms in incontinence in men]. PMID- 6905382 TI - [Nurses shall participate in planning and priority setting]. PMID- 6905383 TI - [Diseases in a dermatologic department and outpatient clinic. 1. Psoriasis is a disease one must learn to live with]. PMID- 6905384 TI - [Nursing in the USA; in a higher degree a career profession]. PMID- 6905385 TI - [Nurses who participated in medical research: we have the troubles while physicians reap the laurels]. PMID- 6905386 TI - [Diseases in a dermatologic department and outpatient clinic. 2. Information to patients with chronic eczema is very important]. PMID- 6905387 TI - [Diseases in a dermatologic department and outpatient clinic. 3. This is the way to perform allergy testing with patch tests]. PMID- 6905388 TI - [Voluntary, developing countries' nurse in a bush hospital in Zambia: patients come to us after they have visited the medicine man]. PMID- 6905389 TI - [Prisoner pardoned and again imprisoned]. PMID- 6905390 TI - [Nurses' comments on the endorsement of the letter concerning nursing home assistants' education: nursing home residents must be satisfied with the replacement of nurses]. PMID- 6905391 TI - [Drug information: agents for the treatment of arrhythmias. 7. Heart electrophysiology]. PMID- 6905392 TI - [Nursing assistants' education superfluous at the present time]. PMID- 6905393 TI - [It could remain the same situation in the nursing home field]. PMID- 6905394 TI - [Welfare institutions Sundholm: residents are not happy with the address]. PMID- 6905395 TI - [Relationship between unemployment in youth and nursing shortage]. PMID- 6905396 TI - [Diseases in a dermatologic department and outpatient clinic. 5. Gonorrhea is continually the venereal disease which occurs with greatest frequency]. PMID- 6905397 TI - [Nurses' comments following the publishing of the letter on nursing home assistants: we risk the disappearance of nurses from nursing homes]. PMID- 6905398 TI - [Visit to a Scottish hospital to study the use of automatic data processing in nursing: uncertain how ADP will be used in personnel management]. PMID- 6905400 TI - [Winter activities]. PMID- 6905399 TI - [Accident project in Copenhagen's District Hospital in Glostrup: there is a need for social guidance in accidents]. PMID- 6905401 TI - [Drug information: agents for the treatment of arrhythmias. Therapeutic main group: anti-arrhythmia agents. 7]. PMID- 6905402 TI - [Breast feeding of infants with allergic parents or allergic siblings: necessary with more research and identical designs]. PMID- 6905403 TI - [Evaluation of risk in the use of ethylene oxide as a sterilization gas: is ethylene oxide an acceptable risk in the hospital environment?]. PMID- 6905404 TI - [Working party has prepared a framework plan for a joint course for personnel groups in occupational health services]. PMID- 6905405 TI - [The Minister of the Interior has no reason to create a scandal]. PMID- 6905406 TI - [Minister of the Interior in the annual hospital administrators' meeting: debt forces us to lower living standards]. PMID- 6905407 TI - [Principles of the nursing process as a basis for administrative nursing plans in a gynecologic department: nursing process still a theoretic plan for many nurses]. PMID- 6905409 TI - [Educational system both oversized and insufficient]. PMID- 6905408 TI - [Status in services for the mentally retarded: most of the residents have no more morbidity than the rest of the population. Interview by Peter Hjorth]. PMID- 6905410 TI - [Proposal for the establishment of a central working-conditions register in occupational health services' management: new industrial risks must be detected as early as possible]. PMID- 6905411 TI - [A study of occupational accidents treated in the emergency room of Copenhagen's District Hospital in Glostrup: could form a basis for measures against occupational accidents]. PMID- 6905412 TI - [Are there any who said admission restriction?]. PMID- 6905413 TI - [Accomplishment of the adjusted nursing education: guidelines delimited for continued work]. PMID- 6905414 TI - [Will nursing homes have acute beds?]. PMID- 6905415 TI - [Drug information: agents for the treatment of arrhythmias. Therapeutic main group: anti-arrhythmia agents. 8]. PMID- 6905416 TI - [The future of school health services and nurses'/community health nurses' role: this single field ought to be performed by nurses]. PMID- 6905418 TI - [A great need for improvement in wage conditions]. PMID- 6905417 TI - [President of the Physicians' Committee concerning services for mentally retarded: one should accept limits to one's own knowledge and need for assistance. Interview by Soren Palsbo]. PMID- 6905419 TI - [Home nurses do not have the necessary clinical experience for assessment]. PMID- 6905420 TI - [Practice experiment for student nurses: students get the chance to experience the patient's situation around the clock]. PMID- 6905421 TI - [Administrative nurse from Kenya on a visit in Denmark: team nursing can be transferred to the new hospital in Nairobi]. PMID- 6905422 TI - [Statement by the Danish Nursing Council on the draft for revised guidelines for home nursing organization: stick to the wish for clear regulations on staff composition]. PMID- 6905423 TI - [Interview with president Kirsten Uth Laursen about the status in services for mentally retarded: we have been everything for a few to organize a nursing service]. PMID- 6905424 TI - [We are tradition-bound and have always appeared and acted like puppets]. PMID- 6905425 TI - [Nursing research in Finland in relation with WHO's Medium Term Programme: stable and functioning system of the center doing nursing research]. PMID- 6905427 TI - [Home nurses' cause from Haderslev: protracted affair about additional wages to members is now concluded]. PMID- 6905426 TI - [Aspects in the psychological care of isolation patients]. PMID- 6905428 TI - [Executive meeting, 16-17 September: this is a great need which real wages will improve now]. PMID- 6905429 TI - [Danish Nursing Council on the situation in services for mentally retarded: thorough analysis of needs should form basis for staff composition]. PMID- 6905430 TI - [Drug information: agents for the treatment of arrhythmia. Therapeutic main group: Anti-arrhythmia agents. 9]. PMID- 6905431 TI - [A home for Danish research in nursing]. PMID- 6905432 TI - [A Danish institute for nursing research is now a reality]. PMID- 6905433 TI - [The future is ours]. PMID- 6905434 TI - [FTF-representative in Work Environment Council: work environment legislation scope supplements Work Environment Council]. PMID- 6905435 TI - [Videotape series about the hospitalized child: information for children and parents in 7 languages]. PMID- 6905436 TI - [Observations about the Danish Hospital Institute should not remain unchallenged]. PMID- 6905437 TI - [Developments benefit in team work with other groups]. PMID- 6905438 TI - [Copenhagen community hospital plans 1981-1992: Minister of Labor shares fear for the consequences of hospital plans]. PMID- 6905439 TI - [Nurse in the clinical-physiological department, Frederiksberg Hospital: nursing process proceeds with great success in the department]. PMID- 6905440 TI - [Drug information: agents for the treatment of arrhythmia. Therapeutic main group: anti-arrhythmia agents. 10]. PMID- 6905441 TI - [Engineer with 20 years practical experience within the hospital system: nurses should be instructed in electrical safety. Interview by Steffen Dalsgaard]. PMID- 6905442 TI - [A question and answer statement about plans for the education of nursing home assistants: we have not received any concrete information on the utilization of nursing home assistants]. PMID- 6905443 TI - ["Danish Nursing Council" out of letter about nursing home assistants]. PMID- 6905444 TI - [1st Scandinavian congress for occupational health nurses: if occupational health services are to function all personnel groups should learn to cooperate]. PMID- 6905445 TI - [Norwegian occupational health nurse at the Scandinavian congress for occupational health nurses: our work can also be a balancing act between management and employee]. PMID- 6905446 TI - [The decade of indifferent decisions]. PMID- 6905448 TI - [Danish Nursing Council's president in the conference on nursing shortage: everybody has the responsibility to remedy the nursing shortage]. PMID- 6905447 TI - [Nurse's dilemma or privilege?]. PMID- 6905449 TI - [When the Scandinavian Nursing Cooperation was 60 years. Scandinavian Nursing Cooperation at reception with world's first female President]. PMID- 6905450 TI - [Social administration's prognosis for the department of the aged expects nursing home assistants' number to increase a lot but gives no statement about problems such as practice capacities]. PMID- 6905452 TI - [Chairmen of the Educational Board for health services at the conference on nursing shortage: demands for education complicate an adequate capacity]. PMID- 6905451 TI - [Nurse instructor after 6 weeks study trip in the USA from West to East: behind it is a professionalism in the best sense of the word]. PMID- 6905453 TI - [Chairman of the Danish Municipal Labor Organization on nursing shortage: unfilled positions not necessarily a sign of nursing shortage]. PMID- 6905454 TI - [Continuity provides a better understanding of a family's living conditions]. PMID- 6905455 TI - [Drug information: agents for the treatment of arrhythmia. Therapeutic main group: Anti-arrhythmia agents. 11]. PMID- 6905456 TI - [Request for care with drug names and strength indications: name changes are to be blamed for a lot of uncertainty in drug administration]. PMID- 6905457 TI - [Organic solvents' toxic action an urgent industrial hygiene problem: studies on damage to health can be detected early]. PMID- 6905458 TI - [Women are always poorly represented]. PMID- 6905459 TI - [Psychosocial consequences of brain damage]. PMID- 6905460 TI - [Economic policy - economic planning]. PMID- 6905461 TI - [Medical society's representative at the conference on nursing shortage: irresponsible not to start with the education of more nurses]. PMID- 6905462 TI - [New legislation on the right to leave of absence and daily allowance in illness and pregnancy: childbirth leave of absence prolonged to 18 weeks - in certain cases to 22 weeks]. PMID- 6905463 TI - [Hospital nurse's experience with job rotation between home care nursing and hospital nursing in Horsens: one makes entirely different patient contacts than in the hospital]. PMID- 6905464 TI - [Home care nurse's experience with job rotation between home care nursing and hospital nursing in Horsens: we will learn enough to work out our problems together]. PMID- 6905465 TI - [Ethical aspects of the medical decision making process: nurses and physicians should be instructed in ethical analysis]. PMID- 6905466 TI - [Representative of the National League of Communities at the conference on nursing shortage: we only recently got an education aimed at the needs of the elderly]. PMID- 6905468 TI - [Hiding behind blinkers is no cutting-down policy]. PMID- 6905467 TI - [Copenhagen's hospital mayor in the conference on nursing shortage: Copenhagen is not in a vicious circle where nursing shortage is concerned]. PMID- 6905469 TI - [Patient participation in their own care: patients' subjective perception of things should be taken seriously]. PMID- 6905470 TI - [Consequences of tightening in pamphlet on "Child care problems": problems and blame overflow to citizens]. PMID- 6905471 TI - [This is not the assistance we dreamed of]. PMID- 6905472 TI - [FTF's president on the crisis in society: we put desire for employment foremost]. PMID- 6905473 TI - [Consequences of tightening in the letter about "Child care problems". 2. Will child care become occupational therapy?]. PMID- 6905474 TI - [Plans for the development of day care facilities in 3 large hospitals]. PMID- 6905475 TI - [Press release from the Equality Council: organization of day care arrangements should continue]. PMID- 6905476 TI - [Specially for nursing instructors: advice and guidance on teaching materials]. PMID- 6905477 TI - [Proposal from the representative of the County Council Society's Hospital Committee to alleviate the nursing shortage: education in modules which can give a certain competence to everybody]. PMID- 6905478 TI - [President of the County Council Society in the conference on nursing shortage: we don't have to go all the way to the wall in our health services]. PMID- 6905479 TI - [Sexual abuse of children: it would help if we had organized a joint child policy]. PMID- 6905480 TI - [Nursing research: profitable knowledge and exchange of experience]. PMID- 6905481 TI - [Experiences from a project-oriented course in the family section of the reorganized basic education: project activities have made us more education conscious]. PMID- 6905482 TI - [Changes - no thanks!]. PMID- 6905483 TI - [Drug information: agents for the treatment of arrhythmia. Therapeutic main group: anti-arrhythmia agents. 13. Digitalis glycosides]. PMID- 6905484 TI - [Health Administration's representative in the conference on nursing shortage: reasons to expect a much more positive result from educational planning]. PMID- 6905485 TI - [Establishment of continued education for home nurses in Copenhagen: it is worthwhile to establish needs and in spite of times to economize. Interview by Steffen Dalsgaard]. PMID- 6905486 TI - [In the year 2000 the level of nursing care will have decreased so drastically that people will be afraid to be hospitalized]. PMID- 6905487 TI - [County Council Society conference on nursing shortage: we cannot organize or educate ourselves out of a nursing shortage]. PMID- 6905488 TI - [County Council Society conference on nursing shortage: problems don't solve themselves by the education of more nurses]. PMID- 6905489 TI - [Their resistance is not going to mean a standstill for necessary education]. PMID- 6905490 TI - [Home health nurse and practicing physician on constipation: the educational effort is the most essential means for treatment of constipation]. PMID- 6905491 TI - [Planning and carrying out educational reorganization in Ribe county: scattered educational places presupposes a strongly aimed program]. PMID- 6905492 TI - Rape: RNs respond. PMID- 6905493 TI - [Learning from others. 4 months study trip to Ben Gurion University]. PMID- 6905495 TI - [Children's home with child care worker education in Tanzania]. PMID- 6905494 TI - [Education for child care worker]. PMID- 6905496 TI - [Nursing care research institute developing health care activities in Finland]. PMID- 6905497 TI - [Nursery school in Bethany]. PMID- 6905498 TI - [Research activities as seen from a school director's viewpoint]. PMID- 6905500 TI - [Health and nursing care instructors' study days in Kalmar, 21-22 November 1979]. PMID- 6905499 TI - [Qualifications for instructors in social service science]. PMID- 6905501 TI - [How did Finland cooperate with WHO's Medium-term Programme in Nursing?]. PMID- 6905502 TI - [Foreign country activities in South Korea and Turkey]. PMID- 6905503 TI - Properdin factor B alleles in patients with idiopathic membranous nephropathy. PMID- 6905504 TI - [The propaedeutic social medicine]. PMID- 6905505 TI - [It's easy for you to talk--the aphasia patient in the hospital]. PMID- 6905506 TI - [Euthanasia: reflections by several hospital clergy on the application of euthanasia and the presentation of living wills]. PMID- 6905507 TI - [Homosexuality and health care. III]. PMID- 6905508 TI - [Nursing assistance to the aged]. PMID- 6905509 TI - [Young Moroccan and Turkish children in the hospital]. PMID- 6905510 TI - [Compiling of a small nursing library]. PMID- 6905511 TI - [Automutilating behavior]. PMID- 6905512 TI - [The why and how of a day center. A look at the development of a day center in a general hospital]. PMID- 6905513 TI - [Euthanasia: reflections by a person asking for euthanasia]. PMID- 6905514 TI - [Nursing: choosing for a science]. PMID- 6905515 TI - [Rehabilitation and team work between hospitals/rehabilitation centers--family physicians/rehabilitation centers]. PMID- 6905516 TI - [Psychiatric nursing--is this professional field still viable?]. PMID- 6905518 TI - [Meal time in the nursing home--a social event?]. PMID- 6905517 TI - [Rooming-in, is it really that necessary?]. PMID- 6905520 TI - [Are we serious about the educational reorganization?]. PMID- 6905519 TI - [Diseases which affect vision]. PMID- 6905521 TI - [This is how patients can feel...the dot on the i]. PMID- 6905523 TI - [The Advisory Committee for education in the field of nursing--a justification from Brussels]. PMID- 6905522 TI - [Role and place of the nurse--a place-determining essay on nursing]. PMID- 6905524 TI - [Unequal persons--on nurses and patients in a psychiatric hospital]. PMID- 6905525 TI - [Various teaching methods for nurses: exercises for the promotion of team work. I]. PMID- 6905527 TI - Test your knowledge: management thought. PMID- 6905526 TI - [Resistance in the providers of assistance]. PMID- 6905528 TI - Test your knowledge: erectile impotence. PMID- 6905529 TI - "Are you listening?". PMID- 6905530 TI - Orthopedic nursing: NAON is growing. PMID- 6905531 TI - The laryngectomized patient: part I. PMID- 6905532 TI - Operating room nursing, then and now. PMID- 6905533 TI - Adaptation to breathlessness. PMID- 6905534 TI - The child with a tracheostomy: a holistic approach to home care. PMID- 6905535 TI - Successful weaning of ventilator-dependent patients. PMID- 6905536 TI - Home care of persons with respiratory problems: optimization of breathing and life potential. PMID- 6905538 TI - Questions about cancer: indicators for patient education. PMID- 6905537 TI - The nurse as clinical consultant. PMID- 6905539 TI - The adolescent with cancer: concerns for care. PMID- 6905540 TI - Assessment of anxiety and depression in the dying patient. PMID- 6905541 TI - Coping with stress through peer support. PMID- 6905542 TI - Promoting informed consent. PMID- 6905543 TI - Economic realities in the treatment and care of the cancer patient. PMID- 6905544 TI - Geographic patterns in the risk of dying and associated factors ages 35-74 years: United States, 1968-72. PMID- 6905545 TI - National estimates of marriage dissolution and survivorship: United States. PMID- 6905546 TI - The who, what, when, why and how of professional negotiations for nurses. PMID- 6905547 TI - The new Medical Practice Act: implications for medical discipline. PMID- 6905548 TI - On the educational front. PMID- 6905549 TI - Health care for all. PMID- 6905550 TI - Prevention of alcoholism. PMID- 6905551 TI - [SHSTF Congres 80. Activities report examined carefully]. PMID- 6905553 TI - [County Council Organization's congress: politicians pretend not to have more than 5000 strikes]. PMID- 6905552 TI - [SHSTF Congres 80: time frame failed]. PMID- 6905555 TI - [Cytology assistants - small group with big problems]. PMID- 6905554 TI - [Social administration study points out: health care varies greatly between county councils]. PMID- 6905556 TI - [Conflict in health care is not dangerous to society]. PMID- 6905557 TI - [Vub- students in Eskilstuna after hospital practice: to be a patient is worse than we thought]. PMID- 6905558 TI - [Public sector in England reduced: St. George in London closes]. PMID- 6905559 TI - [Public employees' right to strike will not be restricted]. PMID- 6905560 TI - [An innocent drink easily becomes abuse]. PMID- 6905561 TI - [Apropos the report on heparin in No. 12: risk of mix up discussed]. PMID- 6905562 TI - [New liability committee judges all personnel]. PMID- 6905563 TI - [Public employees' contribution needs a better political understanding]. PMID- 6905564 TI - [Profile: interview with Martagreta Nilsson by Ulf Backman]. PMID- 6905565 TI - [Revealing UN-report: mass media preserve an old-fashioned view of womanhood]. PMID- 6905566 TI - [New system with minimum wages in new agreement with the private sector]. PMID- 6905567 TI - [MBA and working environment agreement dispute definite in the Fall]. PMID- 6905568 TI - [Important to take a position on the new educational plans]. PMID- 6905569 TI - [Discussion on educational plans: health care with empathy is not enough]. PMID- 6905570 TI - [A gynecologic examination is not like examining ears]. PMID- 6905571 TI - [Labor movement has failed the forgotten and hidden people]. PMID- 6905573 TI - [Nurses' real wages have increased 2 percent in 7 years]. PMID- 6905572 TI - [Poor patient information before minor procedures?]. PMID- 6905574 TI - [Dare to acknowledge that women's nursing care is problematic]. PMID- 6905575 TI - [Increased student practice suggested on evenings, nights, holidays]. PMID- 6905576 TI - [Children may go along to professional courses]. PMID- 6905577 TI - [SHSTF's union lawyer on current regulations for parents' allowance for sick children: no increased responsibility for district health nurses and child health center nurses]. PMID- 6905579 TI - [Difficult for older students to get appropriate continued education]. PMID- 6905578 TI - [Ever more routine tasks for laboratory assistants: we have to clean up fools' jobs]. PMID- 6905580 TI - [These are your representatives' opinions on cooperative decision making agreement]. PMID- 6905581 TI - [A single day lost can destroy the aged's pensions]. PMID- 6905582 TI - [Labor Tribunal: night nurses guilty of working in homes for the aged]. PMID- 6905583 TI - [Swedish round, the yearly around with an airplane full of patients]. PMID- 6905584 TI - [Continued education in Brigitta School in Linkoping: project activities as a form of teaching]. PMID- 6905585 TI - ["Endless patience" provided cytology assistants with improved working environment]. PMID- 6905586 TI - [Criticism against educational plans: proposal's diffusion not guaranteed]. PMID- 6905589 TI - [Swedish Organization of Municipal Employees' congress: intense discussion about members' influence on parliamentary committee analyzed]. PMID- 6905587 TI - [Inger from Tjorn, one of many in refugee camp. Interview by Lars-Kristian Crone]. PMID- 6905588 TI - [Communication important for respirator patients]. PMID- 6905590 TI - [Federal Institute for Radiation Protection in critical letter: we cannot clear our work - staff and money affairs]. PMID- 6905591 TI - [Transfers, consumption, investments, etc. - this is how it is in the public sector]. PMID- 6905592 TI - [Heat camera reveals anesthetic gases]. PMID- 6905593 TI - [In psychiatric care relationships are a necessity]. PMID- 6905594 TI - [District health nurses back in their old and central role]. PMID- 6905595 TI - [Staff worked out improved work organization themselves]. PMID- 6905596 TI - [Ulla has observed the working environment during surgery. An isolated island within the nursing system]. PMID- 6905598 TI - [How would a national section with 20,000 members be able to function?]. PMID- 6905597 TI - [English nurses satisfied with computerization]. PMID- 6905599 TI - [Swedish parent education nothing unique: Yugoslavia has its courses much longer than we]. PMID- 6905600 TI - [County Council Organization's wish following evaluation: more courses for nursing assistants]. PMID- 6905601 TI - [Parents should have better everyday contact with children]. PMID- 6905602 TI - [Proposal on regional health care: dissatisfaction and optimism]. PMID- 6905604 TI - [SHSTF-demand: no changes in management]. PMID- 6905603 TI - [SHSTF says no to more courses]. PMID- 6905605 TI - [I put a bandage on the wounds - not much help]. PMID- 6905606 TI - [One day leave of absence--employer takes off 2 days wages]. PMID- 6905609 TI - [Professional Teachers' Organization rescinds exclusion policy]. PMID- 6905607 TI - [Complaint about negligent treatment by cancer patient]. PMID- 6905608 TI - [Complication with feeding of infant]. PMID- 6905610 TI - [Who will have responsibility for health and nursing care?]. PMID- 6905611 TI - [She works in the entire school. Interview by Viveka Holmertz]. PMID- 6905612 TI - [Education work-out locally: planning committees have the decisive influence]. PMID- 6905613 TI - [Now we should strike for professional competence. Interview by Viveka Holmertz]. PMID- 6905614 TI - [Education and service - are they in agreement?]. PMID- 6905615 TI - [Lena Rosen, SHSTF's first vicechairman: profession should engage in community problems. Interview by Kristina Lindgren]. PMID- 6905616 TI - [Employee Funds discussed: how will public employees secure employment?]. PMID- 6905617 TI - [With shorter service hours still a long Sunday shift]. PMID- 6905618 TI - [District health nurse - who is that?]. PMID- 6905619 TI - [SHSTF on proposal for educational plans: important to formulate goals as well as to be allowed to direct education]. PMID- 6905620 TI - [Swedish Student Nurses' Association demands adequate education in psychiatry]. PMID- 6905621 TI - [Maria and Mikael prepare an exhibit about their work]. PMID- 6905622 TI - [Here one has a stake in continued education for department heads]. PMID- 6905623 TI - [Sam Wenngren, Conflict Committee, about conflicts in the Spring: an investment for the future. Interview by Jan Thomasson]. PMID- 6905624 TI - [Profile: nurse in Mozambique. Interview by Inger Lernevall]. PMID- 6905625 TI - [Public health: occupational health services without white uniforms]. PMID- 6905626 TI - [Sodertoalje Hospital has a long experience: interpreter doesn't solve all problems]. PMID- 6905627 TI - [Social anthropologist Lisbeth Sachs: illness is a relative concept. Interview by Monika Trozell]. PMID- 6905628 TI - [Women's exhibit is a fraud - they don't work for emancipation]. PMID- 6905629 TI - [Temporary solution in Sodermanland: chairman's position is shared]. PMID- 6905630 TI - [Educational meeting: physicians know but little about health problems]. PMID- 6905631 TI - [Work environment problem more than just a cold. Interview by Inger Lernevall]. PMID- 6905633 TI - Supply of nurses - can we meet the demand? PMID- 6905632 TI - [Fibrinolysis activation and the kininogen system and prostaglandin activity in the blood of patients with arteriosclerosis]. PMID- 6905634 TI - Comprehensive examinations: past, present and future. PMID- 6905636 TI - Professionalism in nursing today. PMID- 6905635 TI - Preparation and utilization of the beginning practitioner. PMID- 6905637 TI - Intraglandular transport of 125I-glandular kallikrein in the rat submandibular salivary gland. AB - The transport of radiolabelled rat submandibular gland kallikrein was studied after local administration to the resting and activated rat submandibular gland. The iodinated kallikrein was electrophoretically, immunologically, and biologically indistinguishable from the intact enzyme. After intraductal and intraglandular application the radioactivity in venous effluent was quantitated and characterized. As judged by gel-filtration 125I-kallikrein in venous effluent eluted at a position similar to that seen when the iodinated enzyme was mixed with plasma, but earlier than the elution of 125I-kallikrein in buffer. In plasma, therefore, glandular kallikrein is probably bound to macromolecules. The radioactive fractions in venous effluent did not contain free iodine. Maximum concentration of 125I-kallikrein in venous effluent of resting glands was repeatedly reached about 20 min after intraductal administration. Moreover, the ductal epithelium represented the main permeation barrier since after intraglandular application the maximum venous 125I-kallikrein concentration was reached almost immediately. In activated gland (parasympathetic and sympathetic nerve stimulation), the venous 125I-kallikrein concentration was inversely related to glandular blood flow. We conclude that kallikrein present in the duct lumen or in the interstitium is able to reach the circulation, thereby making possible the local generation of plasma-kinins. PMID- 6905639 TI - Biochemistry and functional aspects of human glandular kallikreins. AB - Human urinary kallikrein was purified by gel filtration on Sephacryl S-200 and affinity chromatography on aprotinin-Sepharose, followed by ion exchange chromatography on DEAE-Sepharose. In dodecylsulfate gel electrophoresis two protein bands with molecular weights of 41,000 and 34,000 were separated. The amino acid composition and the carbohydrate content of the kallikrein preparation were determined; isoleucine was identified as the only aminoterminal amino acid. The bimolecular velocity constant for the inhibition by diisopropyl fluorophosphate was determined as 9 +/- 2 1 mol-1 min-1. The hydrolysis of a number of substrates was investigated and AcPheArgOEt was found to be the most sensitive substrate for human urinary kallikrein. Using this substrate an assay method for kallikrein in human urine was developed. It was shown by radioimmunoassay that pig pancreatic kallikrein can be absorbed in the rat intestinal tract. Furthermore, in dogs the renal excretion of glandular kallikrein from blood was demonstrated by radioimmunological methods. PMID- 6905640 TI - Determination of kallikrein by radioimmunoassay in human body fluids. AB - A sensitive and specific radioimmunoassay for human urinary kallikrein was developed, which allows tissue kallikrein determination in human urine, saliva, pancreatic juice, bile and sweat. In several body fluids a kallikrein-like antigen was found, but not in gastric juice and breast milk. According to gel filtration studies, complex formation of kallikrein with serum proteins or different molecular weight forms of kallikrein in serum and urine may be assumed. Pancreatic kallikrein secretion follows the same pattern after stimulation with secretin and cholecystokinin as trypsin and chymotrypsin in normal individuals. In chronic pancreatitis the kinetic behaviour remains unchanged with respect to the enzyme secretion, but the secretion of kallikrein is reduced to about 20%. PMID- 6905638 TI - The role of the kallikrein-kinin system for hormonal and metabolic regulation. Proceedings of a workshop held at the XIIth Acta Endocrinologica Congress 1979, Munchen, Germany. PMID- 6905641 TI - Impaired renal kallikrein activity and elevated blood pressure normalized by orally applied kallikrein in essential hypertension. AB - Urinary kallikrein excretion was significantly lower in patients with essential hypertension (0.48 +/- 0.05 EU/24 h) than in normotensive controls (1.26 +/- 0.14 EU/24 h). Oral administration of hog pancreatic kallikrein normalized decreased urinary kallikrein and reduced arterial pressure. The treatment-induced rise in urinary kallikrein was due to an enhanced release of endogenous enzyme, as was determined by radioimmunoassay. It is proposed that in the hypertensive patients the low urinary kallikrein excretion reflects a defect in renal kallikrein formation which is normalized by oral kallikrein. The hypotensive action of oral kallikrein, as well as its stimulating effects on renal kallikrein release, suggest that the kallikrein-kinin system is involved in blood pressure regulation and that impaired renal kallikrein activity may be a factor in the maintenance of essential hypertension. PMID- 6905642 TI - "My, these are beautiful flowers". PMID- 6905643 TI - A nurse practitioner program for women's health care. PMID- 6905644 TI - Helping the person with low vision. PMID- 6905645 TI - Acute and chronic asthma: a guide to intervention. PMID- 6905646 TI - Assertiveness training. PMID- 6905647 TI - Infrared therapy for skin ulcers. PMID- 6905648 TI - Tumor cell kinetics and cancer chemotherapy. PMID- 6905649 TI - Reducing stress in patients having cardiac catheterization. PMID- 6905650 TI - Pseudomembranous colitis: a personal account. PMID- 6905651 TI - Nursing in ambulatory settings: a head nurse's perspective. PMID- 6905652 TI - "Student-made, student-played games". PMID- 6905653 TI - Transphenoidal hypophysectomy. PMID- 6905654 TI - Clinical preceptors for new nurses. PMID- 6905656 TI - Caution: objectivity and specialization may be hazardous to your humanity. PMID- 6905655 TI - Programmed instruction: controlling diabetes mellitus. PMID- 6905657 TI - Understanding the electrolyte maze. PMID- 6905659 TI - Organ transplantation: recognizing the donor. PMID- 6905658 TI - Contracting with patient-selected reinforcers. PMID- 6905661 TI - A student sues. PMID- 6905660 TI - Reappraising newborn eye care. PMID- 6905662 TI - How to use methadone for the cancer patient's pain. PMID- 6905663 TI - Double standards? Double standards? PMID- 6905665 TI - Treating the patient, not the constipation. PMID- 6905664 TI - Nursing rounds: care of the patient with a mitral commissurotomy. PMID- 6905666 TI - A survival strategy: kinship networks. PMID- 6905668 TI - Death sentence: an invitation to life. PMID- 6905667 TI - Nurse practitioner/physician relationships. PMID- 6905669 TI - Quadriceps contracture. PMID- 6905670 TI - Empathetic intervention with the widow. PMID- 6905671 TI - Clearance and metabolism of circulating pancreatic proelastase in the rat. AB - A rat model has been employed to study the mechanism of clearance of pancreatic proelastase from the circulation. The clearance of 125I-labeled proelastase was shown to be biphasic, with a half-life for clearance of free 25,000-dalton proelastase of approximately 7-10 min. A slow component of clearance possibly due to proelastase associated with plasma protease inhibitors was also observed. At 10 min after injection of 125I-labeled proelastase into the circulation, the major fraction of the 125I was found to be localized in the kidney. However, appearance of 125I in urine is slow, with 16 h being required for excretion of 50% of the injected 125I as acid-soluble material. Subcellular localization experiments on homogenates of kidneys removed at 10 min postinjection revealed that the majority of the 125I-labeled material was associated with the mitochondrial and lysosomal fraction. Sucrose-gradient centrifugation studies of this fraction demonstrated that the labeled material passes from the membrane fraction to the lysosomal fraction with time. These data demonstrate that the rat kidney constitutes the major site for both circulatory clearance and catabolism of circulating pancreatic proelastase. PMID- 6905672 TI - Severe electrical burn of the eye. AB - The clinical and histopathologic findings in an 18-year-old male who sustained a severe orbital and ocular electrical burn as a result of contact with a "third rail" are described. The third rail was 600 volts positive with respect to the ground, and a maximum of 50,000 amperes was available as current. The anterior segment changes described are considered secondary to heat, as well as electrical energy; whereas the more discrete pathology in the posterior retina and optic nerve was thought to be caused by passage of electric current. Ocular and orbital electric injuries of this severity have rarely been described. PMID- 6905673 TI - CT-evaluation of extraocular muscles - anatomic-CT-correlations. AB - CT evaluation of the extraocular muscles is unsatisfactory in the commonly used axial and coronal planes. Based on the analysis of anatomic and computed tomographic sections and reformations in various planes, optimal examination techniques for the evaluation of the extraocular muscles are discussed. Their anatomic relationship to other clinically and surgically important orbital structures is shown. As a rule, visualization of an eye muscle is optimal if the plane of section or reformation is parallel to its course. Judgments regarding muscle size should be based only on true cross-sections obtained from reformations 90 degrees to the course of the individual muscle. PMID- 6905675 TI - [The functional examination of the visual system by means of delayed triggered VECP (author's transl)]. AB - The VECP represents a brain reaction evoked by fairly abrupt visually perceived changes of one or several environmental features. If the stimulus consists of a finite temporal luminance rise, then the VECP is triggered later as compared to an abruptly appearing stimulus. This delay is an expression of the dynamic input properties of a VECP trigger mechanism. This system evaluates sudden changes of luminance slope and the temporal luminance integral in the first 50 ms after commencement of the stimulus. It may be assumed that deficiencies of the processing of visual information are manifested especially and first of all in a change of the dynamic trigger conditions of VECP. This is shown for colour stimulation (under isolation of the green and red colour mechanism) in different deficiencies of the visual system. PMID- 6905674 TI - The inability of superoxide dismutase to inhibit the depolymerization of hyaluronic acid by ferrous ions and ascorbate. AB - Superoxide radicals were investigated as to their capability of depolymerizing the hyaluronic acid of the bovine vitreous body. Using viscometry it was found that O2 radicals, generated by the hypoxanthine/xanthine oxidase method or the combination of NADH and phenazine methosulphate, degraded hyaluronic acid. This reaction was suppressed by superoxide dismutase, catalase, and peroxidase. In contrast, the depolymerization of hyaluronic acid by oxidation-reduction systems like ascorbic acid or ferrous ions was abolished by catalase and peroxidase while superoxide dismutase showed no effect. PMID- 6905676 TI - [Influence of fundus sclerosis and blood pressure on the ability of compensation of ocular circulation (author's transl)]. AB - The visual fields of nine eyes (nine patients, aged 51--60 years) with fundus sclerosis and relatively low systemic blood pressure, as well as the visual fields from 25 eyes (25 patients, aged 51--60 years) with increased blood pressure, but no ophthalmologic evidence of arteriosclerosis or fundus sclerosis were investigated with the Goldmann Perimeter before and after the application of pressure to the eye. In the first group pressure application resulted in a narrowing of the I/4-isopters and a marked narrowing of the I/2-isopters of the visual field. The blind spot scotomes become larger and are excluded from the I/2 isopters by their marked narrowing. In contrast, the I/4-isopters on the second group of eyes are little influenced by pressure application and I/2-isopters are never narrowed to an extent which excludes the blind spot from the I/2 scale. PMID- 6905677 TI - Ultrasonic and biomicroscopic observations on the vitreous space in patients with idiopathic detachment of the retina. AB - Biomicroscopy and ultrasonography were used to examine the vitreous bodies of 22 unselected eyes with idiopathic detachment of the retina. In addition, the subretinal space was examined acoustically. Optical examination showed severe degeneration of the vitreous body in 17 cases, slight degeneration in four cases, while in one case optical examination was not possible. Acoustic examination yielded the same results. The subretinal space was acoustically heterogeneous in all the eyes examined. In two eyes, the subretinal fluid reflected rapidly moving echoes, in the other 20 the movements were slow. The echoes from the degeneration of the vitreous body were 5-10 dB higher in amplitude than those from the subretinal space. Both optical and acoustic methods should be used to ascertain the disposition of the other eye to detachment of the retina. PMID- 6905678 TI - [Blood-staining of the cornea]. AB - Clinical signs and morphological evidence suggest a primary endothelial damage by the blood-clot in the anterior chamber, and, may be, by raised intraocular pressure, in blood-staining of the cornea. Corneal oedema develops, hemoglobin penetrate into the oedematous corneal stroma peripheral of the edge of Descemet's membrane (Abb. 1, 3). Multiple hemoglobin deposits without iron positive reaction appear in the corneal stroma (Abb. 2-5). Keratocytes take up these fragments and ferritine is formed in the lysosomes (Abb. 6). PMID- 6905679 TI - Phagocytes that invade the vitreous after injury stimulate DNA synthesis in neural retina in vitro. AB - Phagocytes that invade the rabbit vitreous after intravitreal injection were co cultured with cells from the rabbit neural retina. Counts of labeled nuclei after exposure to 3H-thymidine indicate an increase in DNA synthesis by retinal cells exposed to the phagocytes. In contrast, using the same procedures, vitreal phagocytes do not promote DNA synthesis by rabbit dermal fibroblasts in vitro. The apparent proliferation stimulus due to vitreal phagocytes may be functionally related to other macrophage-dependent proliferation-stimulating activities. Since blood components promote vitreal phagocyte invasion, ocular hemorrhage may aggravate some extraretinopathies in part by a phagocyte-mediated stimulation of retinal cell proliferation. PMID- 6905680 TI - The use of a passive hemagglutination test (PHA) in the diagnosis of viral eye diseases. Investigation of lacrimal fluid for the presence of antibody to herpes simplex virus (HSV). AB - The use of a passive haemagglutination test (PHA) with a stable erythrocyte diagnostic preparation sensitized with herpes simplex virus for the detection of antibody to herpes simplex virus (HSV) in the lacrimal fluid of the patients is described. Specific antibody to HSV antigen was found in 68% of the lacrimal fluids taken from patients suffering from herpetic eye disease. In patients with superficial keratitis the antibodies were found more frequently and in higher titers than in deep involvements of the cornea. In patients with keratitis and keratouveitis of unknown etiology, antibody in tears was found in 23%, and in those with inflammatory diseases of nonherpetic etiology, in 14.2%. In clinically normal subjects and patients with non-inflammatory eye affections no HSV antibody could be found in tears. Geometric mean antibody titers in tears of patients with herpes simplex keratitis and keratouveitis were statistically significantly higher than in patients with other diagnoses. The diagnostic importance of HSV antibody found in tears is discussed. PMID- 6905681 TI - Electron microscopical studies on the resorption of vitreous hemorrhages. AB - An electron microscopical study of vitreous structure in 14 eyes suffering from different types and durations of vitreous hemorrhages submitted to vitrectomy showed the typical stages of disintegration of erythrocytes. Neither the type (retrovitreal, intravitreal or combined retro- and intravitreal) nor the duration of the vitreous hemorrhages influenced the histological picture significantly. In cases of shrinkage of the vitreous body the collagen fibrillar meshwork showed normal periodicity of 640 A, partly split and irregular. PMID- 6905684 TI - Ethics in nursing practice and education. PMID- 6905682 TI - The aqueous humor dynamics and the biphasic response in intraocular pressure induced by guanethidine and adrenaline in the glaucomatous eye. AB - Continuous administration of guanethidine (3%) and adrenaline (0.5%) in one eyedrop (GA) induced a biphasic response of intraocular pressure (IOP). In ten patients with primary open angle and seven glaucoma suspects treated with (GA) twice daily during a 7 month period, tonography, and tonometry were performed and the pupil diameter measured 3 and 8 h post-GA. The combined data of both groups in the hypertensive phase, showed an IOP increase of 2.8 mm Hg (P < 0.05), an unchanged coefficient of the outflow, dilated pupil (1.73 mm) (P < 0.005) and a 36% increase of aqueous humor production (P < 0.02). The specific biphasic course of IOP during treatment with GA seems to be caused by fluctuations in aqueous humor production. The increase in aqueous rate during the hypertensive phase could be related to secondary (rebound) vasodilation in the ciliary body and/or to a transient disruption of the blood-aqueous barrier induced by release of prostaglandins. PMID- 6905683 TI - Maintenance therapy of glaucoma patients with guanethidine (3%) and adrenaline (0.5%) once daily. AB - Over a period of 4 months, 16 of 24 patients (30 of 46 eyes) with either primary open angle glaucoma (POAG) or suspected glaucoma were treated successfully with a maintenance dose of guanethidine (3%) and adrenaline (0.5%) combined in one eyedrop (GA) once daily. In the previous month the medication was given twice daily and at the end of 4 months the decrease in intraocular pressure (IOP) was 8.9 mm Hg (33%) compared to 9.9 mm Hg (37%) with twice-daily application; three of four eyes responded just as well to single-daily application as to twice daily application of GA. Once-daily treatment with GA was not successful when the average IOP in the absence of treatment was over 32 mm Hg. The advantages of once daily application were less conjunctival hyperemia, less dilation of the pupils, less ptosis and difficulty reading, plus the advantage that the drops needed only to be applied once a day (patient compliance). The recommended regime for GA therapy in patients with an IOP of less than 32 mm Hg is application of GA twice daily for 1 month followed by a decrease in the dosage to once a day. GA can best be applied in the evening before retiring. PMID- 6905685 TI - Reflections and questions from a nurse in practice. PMID- 6905686 TI - A nursing administrator's view of ethics in practice. PMID- 6905687 TI - Ethical decision making: considerations for future activities. PMID- 6905688 TI - Ethical decision making in an interdisciplinary setting. PMID- 6905689 TI - Arguments for ethics in the nursing curriculum. PMID- 6905690 TI - Ethics in nursing practice and education. Curriculum considerations. PMID- 6905691 TI - A bioethical program for baccalaureate nursing students. PMID- 6905692 TI - Guidelines for implementing the Code for Nurses. PMID- 6905693 TI - New directions for nursing in the '80s. PMID- 6905694 TI - A multidisciplinary approach to offering true alternatives for childbirth. PMID- 6905695 TI - Practice-relevant research development. PMID- 6905696 TI - The role of the registered nurse in a practical new approach to delivery of gerontological care. PMID- 6905697 TI - A nursing model for delivery of primary health care for women. PMID- 6905698 TI - Combining psychiatric-mental health nursing and primary health care nursing in the out-patient setting: a new role. PMID- 6905699 TI - The gerontological nurse's role in implementing geropsychiatric primary nursing. PMID- 6905700 TI - Self-care model for nursing. PMID- 6905701 TI - How attribution theory can shape therapeutic goal setting. PMID- 6905702 TI - An overview of health assessment of the institutionalized elderly. PMID- 6905705 TI - A statement on the scope of high-risk perinatal nursing practice. PMID- 6905703 TI - Mental health assessment as a part of the assessment of physiological status of the elderly. PMID- 6905704 TI - Endorphins and mental illness: a summary of research findings and implications for nursing. PMID- 6905706 TI - Enrolling in a baccalaureate program in nursing: general information and guidelines. PMID- 6905707 TI - Nursing: a social policy statement. PMID- 6905708 TI - A sensitive and specific enzyme assay for elastase activity using alpha [3H]elastin as substrate. PMID- 6905710 TI - Nurses ponder impact of Reagan sweep. PMID- 6905709 TI - [Experimental investigations concerning the specific concentrations of kininogenases in testis and epididymis]. AB - In an experimental study the localisation and activity of hog-pancreatic Kallikrein was investigated immunologically and enzymatically in the testis and epididymis. A concentration of Kallikrein was observed in the Ductus epididymis, but the same could not be seen in the germinal epithelium of the testes. PMID- 6905711 TI - Changes predicted for health programs. PMID- 6905712 TI - Non-nursing tasks inflate shortage. PMID- 6905713 TI - A time for sharing our commitment to nursing. PMID- 6905714 TI - Clinical significance of tolerant strains of Staphylococcus aureus in patients with endocarditis. AB - We have studied 50 cases of endocarditis and 54 cases of bacteremia due to Staphylococcus aureus to ascertain the clinical significance of the newly described phenomenon of tolerance. In 32 of the patients with endocarditis and 35 of those with bacteremia strains were classified as tolerant (minimum bactericidal concentration/minimum inhibitory concentration greater than or equal to 16). Patients with endocarditis due to a tolerant strain responded less favorably than did patients with a sensitive strain. A larger number of patients with a tolerant strain had prolonged fever (58% versus 19%), a higher mean number of complications (1.6 versus 0.73), a greater number of intensive-care unit admissions (66% versus 33%), and a higher mortality (25% versus 11%). In contrast there was no difference in response to therapy in bacteremic patients without endocarditis having sensitive and tolerant strains. We conclude that infection with a tolerant organism adversely influences the outcome of staphylococcal endocarditis. PMID- 6905715 TI - Antimicrobial susceptibility testing of Streptococcus pneumoniae by micro-broth dilution. AB - Thirty-three clinical isolates of Streptococcus pneumoniae were tested for susceptibility to penicillin and ampicillin by a standard agar dilution method. Results were compared to those obtained using a micro-broth dilution technique in which Mueller-Hinton broth was supplemented with 5% difibrinated whole sheep blood. Among the 33 strains, 2 were resistant (minimal inhibitory concentration, 8 micrograms/ml), 10 were relatively resistant (minimal inhibitory concentration, 0.12 to 0.5 micrograms/ml), and 20 were susceptible (minimal inhibitory concentration, less than or equal to 0.06 micrograms/ml) to penicillin by both methods. Only one stain showed a two-dilutional-step difference by micro-broth and agar dilution testing resulting in categorization as relatively resistant by the former method but susceptible by the latter. A 1-microgram oxacillin disk correctly identified 11 of the 12 resistant strains. The micro-broth dilution technique is a reliable, simple method for penicillin or ampicillin susceptibility testing of pneumococci and economically feasibile to perform manually or with a semiautomated system. PMID- 6905716 TI - Tritium labeling of thermolysin, elastase, and ribonuclease by exposure to tritium gas at low pressure. PMID- 6905717 TI - Rehabilitation nursing core curriculum report. PMID- 6905718 TI - Recruiting rehabilitation nurses. PMID- 6905719 TI - Neurophysiology of sexual response in spinal cord injury. PMID- 6905720 TI - The challenge of rehabilitation nursing in the '80s. PMID- 6905721 TI - Support group improves quality of life. PMID- 6905722 TI - From the President's pen: ethics and honesty--are they really one? PMID- 6905723 TI - Changing nurses' participation in health planning. PMID- 6905724 TI - Tertiary nursing education: a conversation about changing nursing care. PMID- 6905725 TI - Nurse education in Thailand and questions about the direction of nursing education in Australia. PMID- 6905726 TI - "Man as a total being"--RANF's new Nursing Officer describes ideals and goals. PMID- 6905727 TI - Preparing nurses for an expanded role in primary health care delivery. PMID- 6905728 TI - Stress and the child. PMID- 6905729 TI - An evaluation of the aims, tasks and priorities of the Infant Welfare Service in Victoria. PMID- 6905731 TI - When the 'biological clock' runs out: late night mortality. PMID- 6905730 TI - Creative crisis and the role of the chaplain. PMID- 6905732 TI - Nursing education - the saga to date. PMID- 6905733 TI - Racism. PMID- 6905734 TI - What of the future? PMID- 6905735 TI - Restore to rights. PMID- 6905736 TI - New nursing home concept for Australia's oldest residents. PMID- 6905737 TI - The conditions of aborigines. PMID- 6905738 TI - Antidotes. PMID- 6905739 TI - The role of education in breaking the poverty cycle. PMID- 6905740 TI - The Aboriginal Community College: a simple response to complex conditions. PMID- 6905742 TI - The future of the Aborigines. PMID- 6905741 TI - Aboriginal health: the cause of bad health standards. PMID- 6905743 TI - Brown men and red sand. PMID- 6905744 TI - Aboriginals, the law, and the future. PMID- 6905745 TI - Aboriginal women today. PMID- 6905747 TI - Hospital drama: a new role for video? PMID- 6905746 TI - Aboriginal women in the health role. PMID- 6905748 TI - You are special. PMID- 6905749 TI - The 'natural death' Bill. PMID- 6905750 TI - Divorce: the untreated cancer. PMID- 6905752 TI - The Cleft Palate and Lip Society. PMID- 6905751 TI - Patients' Bill of Rights and Responsibilities. PMID- 6905753 TI - Observing and recording behaviors of hospitalised children. PMID- 6905754 TI - Nurse and aide: nursing assistant's point of view. PMID- 6905755 TI - The delivery of Aboriginal health care--a community based approach. PMID- 6905756 TI - [A word from our President: 5 months later]. PMID- 6905757 TI - [Professional assessment: for a better understanding of its basic mechanisms]. PMID- 6905758 TI - [Continuing education: principles of body mechanics]. PMID- 6905759 TI - [Authorization regulations and the law]. PMID- 6905760 TI - [Mr. Jacques-Yvan Morin, Minister of Education, and professional education of youth in Quebec]. PMID- 6905761 TI - Cardiac effects of vanadate. PMID- 6905763 TI - Influence of vanadate on electrophysiological and contractile parameters of atrial myocardium. AB - Whereas vanadate increases isometric force of contraction in stimulated rat left atria (EC50: 36.6 mumol/1), it decreases force of contraction in guinea-pigs (EC50: 4.7 mumol/1). Action potential duration at 90 and 30% repolarisation is decreased in guinea-pig atria by 70 and 60%, but in rat atria by only 40 and 7% respectively. Whereas the time course of the negative inotropic action is rapid and correlates with that of the shortening of the action potential, there is no relationship between action potential changes and the slowly developing positive intropic effect. Negative and positive inotropic actions seem to be the result of two superimposed processes, whose kinetics suggest an extra- and intracellular site of action. Na+, K+-ATPase prepared from rat and guinea-pig atria and ventricle is inhibited by vanadate to a similar extent: IC50 (mumol/1) rat: atria 1.05, ventricle 0.49; guinea-pig: atria 0.75, ventricle 0.62. This indicates that the discrepancy in inotropy cannot be explained by the different sensitivity of the Na+, K+-ATPase to vanadate. PMID- 6905762 TI - Effect of vanadate on myocardial force of contraction. AB - Ammonium vanadate (NH4VO3; 50-1000 microM) increases the force of contraction of isolated electrically driven cat papillary muscles in a concentration-dependent manner. The positive inotropic effect (PIE) of NH4VO3 became significant at 50 microM and was maximal at 500 to 1000 microM. It was accompanied by an increase in the rate of force development, in the rate of relaxation and in relaxation time of the isometric contraction. Similar results as with NH4VO3 were also observed in the presence of 1 microM propranolol, 5 microM phentolamine or after reserpine-pretreatment (5 mg/kg i.p.). These results indicate that vanadate produces a direct PIT in ventricular cardiac muscle which is unlikely to be mediated by alpha- or beta-adrenoceptor stimulation. In cat left atrial strips, however, vanadate ions produced a negative inotropic effect through a hitherto unknown mechanism. Vanadate effects similar to those observed in the cat heart were obtained in ventricular and atrial preparations from bovine hearts. PMID- 6905764 TI - Vascular effects of vanadate. AB - The present experiments demonstrate that vanadate (sodium orthovanadate) given i.v. to anesthetized cats induces a marked, transient and reversible constriction of visceral arteries, including the renal artery, whereas the femoral and carotid artery escape constriction. The constriction of the renal artery is accompanied by a pronounced reduction of glomerular filtration rate and urine production. The vasoconstriction appears to be caused by a direct effect of vanadate on the vessel wall, but the mechanism of action is not established. PMID- 6905765 TI - Stimulation of human cardiac adenylate cyclase by vanadate. AB - Experiments have been carried out to characterize the influence of the positive inotropic trace element vanadium (used as Na3VO4) on beta-adrenergic receptor coupled adenylate cyclase activity from human myocardium. Na3VO4 (10(4)M) stimulates basal activity as well as isoprenaline (10 microM)- and Mg2+ (20 mM) activated enzyme activity 1.5-2.4-fold. In contrast, adenylate cyclase activity in the presence of maximally activating concentrations of Gpp(NH)p (10 microM) cannot be further increased by Na3VO4. The results confirm the assumption (5) that vanadate stimulates adenylate cyclase by interacting with the nucleotide binding site of this enzyme. PMID- 6905766 TI - The Singapore heroin control programme. AB - In 1975 Singapore experienced a sudden heroin epidemic, and within two years an estimated 3 per cent of the males, 15-24, were involved. In 1977 the Government responded with an all-out enforcement strategy aimed at rapid containment. Demand reduction involved the large scale arrest of suspected users, and the immediate commitment of those with positive urines to Drug Rehabilitation Centres. The primary rehabilitation emphasis is on instilling discipline, social responsibility and sound work habits. Releases are placed on two years of compulsory supervision with a 5-day cycle for reporting and urine specimens. Sixty-three per cent show no detected drug use within the first year of supervision. Supply reduction efforts are equally strong and, while these were not immediately successful in limiting availability, heroin is currently very scarce and expensive. While there is some evidence of the substitution of cannabis, psychotropic drugs and alcohol, the number of new heroin cases is minimal. Overall, the epidemic appears to have been controlled. PMID- 6905768 TI - The role of the general administration in drug abuse control in Egypt. PMID- 6905767 TI - New light on the maturing out hypothesis in opioid dependence. PMID- 6905769 TI - Herbicidal treatments for control of Papaver somniferum L. AB - Fifty-five commercially available herbicides were evaluated for possible use to destroy illicit opium poppy crops (Papaver somniferum). In the first stage, herbicides were sprayed on poppy plants grown in containers. The following compounds killed poppy plants: (a) herbicides with typical foliar activity- amitrole, bromoxynil, 2,4-D, glyphosate, ioxynil and paraquat; and (b) herbicides with root and foliar activity--the triazines ametryn, atrazine, metribuzin, prometryn, simazine and terbutryn; the substituted ureas benzthiazuron, chloroxuron, diuron, fluometuron, linuron, methabenzthiazuron, neburon and phenobenzuron; and the miscellaneous compounds karbutilate, methazole, oxadiazon and pyrazon. Severe but sublethal injury was caused by cycloate, EPTC, molinate, pobulate, cacodylate + MSMA, ethofumesate, perfluidone and phenmedipham. Abnormal development of vegetative or reproductive parts of the plant was induced by benefin, butralin, dinitramine, pendimethalin, trifluralin, diphenamid, napropamide, dalapon and propham. Efficient herbicides with negligible persistence in soil at the doses applied were evaluated on poppy plants in the field at various stages of growth. Small plants were severely injured by 2,4-D, killed rapidly by bromoxynil, ioxynil, paraquat (in mixture + diquat), and more slowly by glyphosate and metribuzin. The resistance to herbicides increased with the age of the poppy plant. Severe damage with partial kill of developed plants was obtained with bromoxynil, ioxynil, glyphosate, and paraquat + diquat; the last treatment produced the fastest effect. PMID- 6905770 TI - Quantitative in situ fluorometry of LSD by HPTLC. PMID- 6905771 TI - Applying the Neuman model to nursing practice with hypertensive clients. PMID- 6905772 TI - Where do we stand? District nursing--here and now. PMID- 6905773 TI - Idiopathic hypercalciuria in calcium nephrolithiasis. PMID- 6905774 TI - "Retreading" the experienced diabetic. PMID- 6905775 TI - A teaching plan for pregnant diabetics. PMID- 6905776 TI - Third party payments. PMID- 6905777 TI - Compliance from a patient's perspective. PMID- 6905778 TI - Profiles of diabetes education in 1979; results of three surveys. PMID- 6905779 TI - To learn...to teach...to grow. PMID- 6905780 TI - Teaching-learning strategies. PMID- 6905781 TI - Creative growth makes a difference. PMID- 6905782 TI - Establishment of a diabetes youth group. PMID- 6905783 TI - Diabetes teaching: a close-up. PMID- 6905784 TI - The genetics of diabetes. Nursing roles and responsibilities. PMID- 6905786 TI - Your prospective interview: the preparation process. PMID- 6905785 TI - Planning for recertification. PMID- 6905787 TI - Standards for nursing care of the critically ill. PMID- 6905788 TI - The AACN nominating process. PMID- 6905789 TI - Observations on the development of the critical care nurse. PMID- 6905790 TI - HERA: health environment responsibility arousal. PMID- 6905791 TI - [Pneumococcal meningitis partially resistant to penicillin]. PMID- 6905793 TI - [Activation of epilepsy-typical potentials in the EEG (author's transl)]. AB - In the case of seizures which are difficult to diagnose, the demonstration of epilepsy-typical graphoelements in the EEG confirms the suspected presence of an epilepsy. Activation methods are employed, since epilepsy-typical potentials may be even absent in established cerebral convulsibility in the routine wake EEG. The purpose of these method is the activation of epilepsy-typical potentials in patients, whereas the activation should not be so strong that those potentials may also be activated in healthy persons - since they can be provoked by a sufficiently strong stimulation in any individual. Hyperventilation, photostimulation, sleep, sleep deprivation and, in addition, drug provocation with Bemergrid, have proved most effective in routine diagnostic procedures; the diagnostic significance of the latter is still most problematic. - The various activation methods show a variably marked effect in the different types of seizures. PMID- 6905792 TI - [Importance of predisposing factors and personality characteristics in cluster headache patients (author's transl)]. AB - Predisposing factors and concomitant diseases were examined in cluster headache patients. A positive or negative correlation to a particular disease, e.g. gastrointestinal ulcerative disease, could not be showen. Factors indicating a genetic predisposition could also not be found. In the Freiburg Personality Inventory cluster and migraine patients had an essentially normal profile; however, both groups evidenced a tendency towards psychosomatic reactions. PMID- 6905794 TI - Isolation and characterization of native single-chain porcine pancreatic kallikrein, another possible precursor of urinary kallikrein. AB - Porcine pancreatic kallikrein B' was isolated from partially purified prokallikrein B activated "spontaneously" (most probably due to the action of some contaminating proteinase). Upon dodecyl sulfate electrophoresis after reduction, the enzyme migrated like the single-chain alpha-kallikreins A from submandibular glands and urine of the pig, indicating an apparent molecular weight of about 36,000. Evidently, porcine pancreatic kallikrein B' is also a single-chain alpha-kallikrein, in contrast to the two-chain beta-kallikrein obtained by the usual isolation procedure from autolyzed porcine pancreas. The amino acid composition of kallikrein B' is very similar to that of the other porcine glandular kallikreins and it too contains glucosamine. The specific activities of kallikrein B', as measured under various conditions, also resemble closely those of porcine urinary and submandibular kallikreins, as do the rates of the enzyme-catalyzed hydrolyses of various amino acid ester substrates. During the hydrolysis of Bz-LysOMe or low concentrations of Bz-ArgOEt, the same strange biphasic course of the reaction is seen, as observed previously in the case of the other single-chain porcine kallikreins. Consequently, the properties of native porcine pancreatic kallikrein are well consistent with the suggestion that urinary kallikrein represents filtered enzyme of pancreatic and submandibular origin. Further available evidence for this and the alternative hypothesis of synthesis of urinary kallikrein in the kidney is discussed. PMID- 6905795 TI - Comparison of Naja n. naja and Naja h. haje cobra-venom factors: correlation between binding affinity for the fifth component of complement and mediation of its cleavage. AB - Two cobra-venom factors, one from Naja n. naja (CVFn), the other from Naja h. haje venom (CVFh), have been purified and compared, functionally and structurally. Both factors interacted with human factors B and DS to form a potent C3 convertase, CVFBb. However, while the convertase formed with CVFn did also efficiently cleave C5, CVFhBb had very little C5-cleaving potency only, in particular when human C5 was used as substrate. Studies with agarose-linked CVF preparations indicated that CVFh has only low binding affinity for C5gp and C5hu whereas CVFn binds to both C5 species with much higher affinity. Since C5-binding (to CVF or to C3b) is a prerequisite for its cleavage by C3/C5 convertases, the difference in binding potency explains the different C5-cleaving activity of the two CVF preparations. When a ligand for C5, surface-fixed C3b, is present, CVFhBb is also capable of cleaving C5. The difference in activities of CVFn and CVFh is reflected in their different potency to interfere with immune haemolysis and in causing indirect lysis by their complexes with activated factor B. By gel chromatography of the CVF preparations in C5-containing medium, a stoichiometric complex CVFn-C5 (1 + 1) could be demonstrated. An analogous complex of C5 was neither found with CVFh, nor with C3hu or soluble C3bhu. Structural differences between CVFn and CVFh were revealed by immunodiffusion analysis and by polyacrylamide-gel electrophoresis in presence of SDS. The data available so far provide, however, no clear information about the structure of the C5 binding site. PMID- 6905796 TI - [Maternal breast feeding]. PMID- 6905797 TI - [Diet in myocardial infarction]. PMID- 6905799 TI - [Contraceptives--return of the condom]. PMID- 6905798 TI - [Dietary habits and nutrition education. Interview by Dr. P. Hermann]. PMID- 6905803 TI - Research as an inactional situation: objectivity in the interview. PMID- 6905802 TI - [Burns]. PMID- 6905800 TI - [Esophageal stenosis]. PMID- 6905801 TI - [The nurse in psychiatry: delirium. I]. PMID- 6905804 TI - Personality profiles for qualified nurses: possible implications for recruitment and selection of trainee nurses. PMID- 6905805 TI - Occupational orientations in nursing in Britain. PMID- 6905807 TI - Nurses' smoking behaviour: review and implications. PMID- 6905806 TI - Formation of professional images among Israeli student nurses. PMID- 6905808 TI - Childbirth. PMID- 6905809 TI - The role of the nurse in the management of deliberate self-poisoning in the general hospital. PMID- 6905811 TI - Topical antibiotic ointments for staphylococcal nasal carriers: survey of current practices and comparison of bacitracin and vancomycin ointments. AB - One measure used in the management of staphylococcal disease outbreaks in newborn nurseries is to obtain nasal cultures from nursery personnel and then treat nasal carriers with topical antibiotic ointments. Because recent infection control guide-surveyed current practices in larger hospitals in the U.S.A. Seventy-one percent of respondents indicated that they would obtain nasal cultures from personnel during a staphylococcal disease outbreak, and 40% indicated that they would prescribe topical antibiotic ointments for personnel with positive nasal cultures before the results of bacteriophage typing became known. Because little has been written about the efficacy of topical intranasal antibiotics within the past decade, we compared bacitracin ointment with a vancomycin ointment for treatment of the staphylococcal nasal carrier state. Both ointments reduced nasal carriage in the majority of instances. However, similar reduction was also observed in an untreated control group. The need for different approaches to the problem of nasal carriers is discussed. PMID- 6905810 TI - Hospital costs of nosocomial infections: a prospective three-month study in a community hospital. AB - A prospective three-month study of the hospital costs associated with nosocomial infections was done in a 390-bed, 30-bassinet community-teaching hospital early in 1978. All hospital charges for diagnostic and therapeutic services required by nosocomial infections, and added length of stay due to the infections, were recorded. During the study period 123 infections occurred in 104 patients (a 2.7% incidence, considering the 4,485 patients discharged during this time). The average length of stay was prolonged 3.0 days for all nosocomial infections; this accounted for about half of the $636 average hospital charges for each nosocomial infection. The 65 nosocomial urinary tract infections prolonged the length of stay an average of 0.6 days and the total hospital charges were $146 for each infection, leading us to believe that the proportion of nosocomial infections at any given site may greatly alter the "average" cost of nosocomial infections. Our data from a community hospital show a shorter prolongation of length of stay and lower hospital costs when compared with the few other studies in the literature. PMID- 6905812 TI - Describing sample data. PMID- 6905813 TI - Hospital-acquired staphylococcal infection transmitted by hospital personnel. PMID- 6905814 TI - A statewide characterization of hospital infection control practices and practitioners. AB - Selected features of infection control programs among the 163 general hospitals in Tennessee were surveyed in 1976 and 1979. Each hospital but one had a designated infection control practitioner. Three-fourths of the hospitals had fewer than 200 beds and most were in rural areas. The practitioners in these small hospitals worked in an isolated professional milieu: few (4%) had attended a basic training course or were members of a national (11%) or local (16%) infection control association. They also had significantly less access to standard infection control resource publications than did practitioners in large hospitals. Use of aqueous quaternary ammonium compounds for disinfection was reported by 37% of all hospitals in 1979; 68% of hospitals routinely performed bacteriologic cultures of personnel or the environment. In contrast, only 3% of hospitals did not have a policy specifying the use of sterile closed-system drainage of indwelling bladder catheters. Although these practices varied somewhat by hospital size, the differences were not statistically significant. Modest improvement in each parameter was noted since 1976. Pathology was the most common medical specialty (34%) among chairman of infection control committees; internal medicine and pediatrics accounted for only 13%. The practice of routine microbiologic monitoring was significantly more common among hospitals with chairmen who were pathologists. The implications of these findings for national priorities in hospital infection control are discussed. PMID- 6905817 TI - Testing the differences between means. PMID- 6905815 TI - Surveillance for nosocomial infections: can the sources of data be reduced? AB - With the goal of achieving economy in infection control surveillance we tested the relative efficiency of the various surveillance sources for detecting nosocomial infections (NIs). We reviewed the initial and final surveillance sources of 415 NIs at Hackensack Hospital during an 11-month period; cultures were taken on most of the patients with NIs. Positive microbiology cultures were the initial sources in 64.8% of NIs and secondary sources in 23.6%. Chart review of patients with positive cultures added another 2.9%. Therefore, 91.3% of NIs could have been detected by positive culture reports. The remainder were discoverable by notification from nurses, or by studying admission cards or temperature rounds. Although the NIs missed by lack of a positive culture report often were significant infections, these alternate methods of surveillance did not help to detect any clusters of infections that could be traced to a particular source among the staff or the environment. PMID- 6905816 TI - Gentamicin and tobramycin resistant gram-negative bacilli in a community hospital. AB - The incidence and spectrum of resistance to gentamicin and tobramycin among gram negative bacilli (GNB) isolated in a community hospital over a one-year period were studied. The overall incidence of resistance was 3.7%. Pseudomonads constituted almost half of the resistant organisms. The majority of resistant GNB was isolated from the respiratory and urinary tracts. Acquisition of resistance was correlated with both the total use of gentamicin in the hospital and recent treatment of individual patients with gentamicin plus tobramycin. The overall incidence of resistant isolates (3.7%) and the incidence of resistance for the enterobacteriaceae (1.9%) were lower than rates reported by comparable studies at several university or municipal hospitals. PMID- 6905818 TI - Superior vena cava syndrome as the initial clinical manifestation of sarcoidosis. PMID- 6905819 TI - Complete atrioventricular block, shock, and hyperkalemia induced by toxic adenoma of the thyroid gland. AB - The case of a 74-year-old woman with toxic thyroid adenoma, presenting as complete heart block, is described. Upon admission the patient was in a state of circulatory collapse with metabolic acidosis and hyperkalemia. After initiation of right ventricular pacing the circulatory and metabolic disorders rapidly normalized without any other specific therapy. Since treatment and attainment of the euthyroid state the patient has had no conduction delays or arrhythmias. Complete heart block in thyrotoxicosis is uncommon and previous reports relate to its occurrence in Graves' disease, usually complicated by infectious disorders. This is the only case known to us of complete heart block in toxic thyroid adenoma. PMID- 6905820 TI - Symptomatic abdominal bronchogenic cyst mimicking acute ischemic heart disease. AB - A 57-year-old female patient presented with a symptomatic abdominal bronchogenic cyst that was associated with ECG changes. The patient's clinical presentation with chest pain, ST and T wave changes, and rate-related bundle branch block initially suggested a myocardial infarction. The ECG reverted to normal after the cyst was removed. The physiologic origins of these observations are unknown. PMID- 6905822 TI - The new inotropic drug, dobutamine. PMID- 6905823 TI - An electrocardiographic study of myocardial infarction. PMID- 6905821 TI - The physiologic basis for combined nitroprusside-dopamine therapy in post myocardial infarction heart failure. PMID- 6905824 TI - Type I hypersensitivity and anaphylaxis from insect stings. PMID- 6905825 TI - Sudden death in the six-month postinfarction period. AB - Complex ventricular arrhythmias that appear during convalescence following an MI and up to a period of 6 months post MI are known to increase the risk of sudden death. The majority of subjects with this complication have above-normal left ventricular filling pressures, a hemodynamic measure of congestive heart failure. In this clinical setting, it is therefore important to consider and search for evidence of congestive heart failure. Drug therapy for arrhythmias is more effective in patients whose congestive heart failure has been adequately treated. Not infrequently, after cardiac compensation the arrhythmia subsides without any further intervention. PMID- 6905826 TI - The unit of measure for systemic vascular resistance (SVR) PMID- 6905827 TI - A nursing assessment of unions. PMID- 6905829 TI - A simplified concept of complete physiological monitoring of the critically ill patient. PMID- 6905828 TI - A simple, programmable calculator technique for dosage determination and administration of drugs by continuous infusion. PMID- 6905830 TI - Autotransfusion: current status. PMID- 6905831 TI - A method of intraoperative placement of atrial pressure line. PMID- 6905832 TI - Respiratory disorders during sleep. Part II. PMID- 6905833 TI - Lidocaine prophylaxis: an alternative to computerized arrhythmia monitoring. PMID- 6905834 TI - Monitoring technicians--the critical interface. PMID- 6905836 TI - Heart rate and blood pressure responses to sexual activity and a stair-climbing test. PMID- 6905835 TI - Respiratory disorders during sleep. Part I. PMID- 6905837 TI - Positioning the patient with intracranial hypertension: how turning and head rotation affect the internal jugular vein. PMID- 6905838 TI - Prolonged rehabilitation of patients after acute myocardial infarction and its effects on a complex of physiological variables. PMID- 6905839 TI - Nurse acceptance of a computerized arrhythmia monitoring system. AB - Implementation of a sophisticated computerized arrhythmia monitoring system in our institution initially met with negative attitudes from the critical care nurses in the ICCU and IMCU. This negative response can be attributed to several factors: (1) reliability of a computer monitoring system, (2) requirement of extensive education and training in the operational aspects of the system, and (3) time-consuming interface to the system. The nurses' responsibility to direct patient care did not allow enough time to properly adjust program parameters and react to the system. However, the comparative study performed by Zencka and colleagues overwhelmingly supported the effectiveness of the use of this system in the clinical setting. The introduction of the Arrhythmia Monitoring Technician obviated these problems. The technicians are responsible for the total operation of the monitoring system. Interface to the system occurs on two levels: (1) technician interface to the system by the adjustment of parameters and the verification of detected abnormalities and (2) technician interface to the nurses by notification of detected arrhythmias via remote transmission. In a recent survey, a majority of the nurses in the ICCU and IMCU indicated their positive support of the effectiveness of this computerized arrhythmia monitoring system. Critical care nurses in our institution consider computerized arrhythmia monitoring an essential component in the provision of quality patient care. PMID- 6905840 TI - Leveling when monitoring central blood pressures: an alternative method. AB - Monitoring central hemodynamic pressures is an important part of total assessment by those who assume responsibility for total care of those critically ill patients in need of invasive monitoring. In such patients frequent measurements are required during the course of the several days, on a 24 hour basis. If the data are to be highly reliable and valid, particular attention must be given to the important aspects of leveling the two reference points by the several nurses who assume such responsibility. The two methods of leveling now in use, sighting and use of the spirit level, leave the question of such consistent accuracy in doubt. This alternative method of using water in a closed loop of tubing for leveling, with its definite and necessary steps, may seem to be time consuming to the already busy critical care nurse. The ability to master the necessary technique after a few practices and to gain speed and confidence in performing the steps has been demonstrated clearly by those nurses who have received instruction and supervision in this approach to leveling and monitoring central blood pressures. The loop of tubing used for this alternative method is easily made from materials readily available in each critical care unit. Its looped construction allows it to be placed for convenience and accessibility to the patient undergoing frequent hemodynamic monitoring, and can be used for a number of similarily placed patients. PMID- 6905841 TI - Infusion pump artifacts: the potential danger of a spurious dysrhythmia. PMID- 6905842 TI - Critical care nursing orientation: a comparison of teaching methods. AB - In summary we have shown in this small group of 32 nurses that the PIM approach is as effective a method for critical care orientation as traditional classroom teaching. The savings in instructors' and orientees' time via PIMs result in dollar savings; but more importantly, the PIM was found by our orientees to be more satisfying. PIMs encouraged flexibility and individualized attention, and by self-pacing allowed several nurses to begin practice in the critical care setting earlier than usual. In light of the high cost of orientation, one finding that warrants further exploration is the orientee's uncertainty of remaining in critical care nursing. It is possible that as the orientee becomes socialized into the critical care setting, her values, attitudes, and commitment to remain may change over time. Future follow-up will help us to examine changing attitudes as these nurses become acclimated to the critical care setting. Head nurses and staff development instructors play a major role in preventing frustration and turnover and in creating a positive climate for growth. PMID- 6905843 TI - Effects of nurses' knowledge of teaching-learning principles on knowledge of coronary care unit patients. PMID- 6905844 TI - A study of the difference in health knowledge gained through formal and informal teaching. PMID- 6905845 TI - A study of escape-capture bigeminy. PMID- 6905846 TI - New antibiotics--uses and dangers. PMID- 6905847 TI - Torsade de pointes. AB - Prolonged QT or QU intervals can be caused by a variety of conditions which include drugs, electrolyte imbalance, and acquired and congenital diseases. This finding is associated with life-threatening ventricular arrhythmias that, at times, have unusual morphologies characteristically named "torsade de pointes." Treatment, when iatrogenic, is obvious--when due to acute acquired diseases, therapy is supportive until the acute phase passes. In congenital prolonged QT syndromes, primidone (Mysoline) recently has been found to be successful in long term management. PMID- 6905849 TI - Entry into practice--a nuts-and-bolts appraisal. PMID- 6905848 TI - Cardiopulmonary resuscitation. PMID- 6905850 TI - Successful 'normalizing' tactics of parents of chronically-ill children. AB - To be or to parent a chronically-ill child is a difficult experience. Parents can initiate 'normalizing' tactics that alleviate the child's feeling of being different and enable a sense of control with the possibility to influence the quality of life of the child and the family. Following up among 20 parents of chronically-ill children, the author was able to identify a number of principles which underlined the 'normalizing' tactics. These principles, it is suggested, should be helpful to nurses and other health workers when guiding and advising parents and others who come into daily contact with chronically-ill children. PMID- 6905851 TI - Training for team care. AB - The aim of this paper is to highlight some of the findings of a research study concerned with the perception of general practitioner trainees, health visitor, district nurse and social work students towards the primary health care team. Areas of role understanding; role restriction/role euphoria and high referral of problems to others are illustrated. The results suggest a need for role learning experiences during training which are subsequently extended and reinforced by interdisciplinary participation in simulated patient management experiences. The idea of team care in the United Kingdom was first mooted as early as 1920 when a committee under the chairmanship of Dawson proposed that doctors should work in teams from health centres. This suggestion was destined to lie dormant until the 1960s, when due to a more favourable political, social and economic climate, the idea was rejuvenated. District nurses and health visitors became associated with doctors in general practice and such terms as 'attached', 'aligned', 'linked' and 'in liaison with' were in vogue (C.E.T.H.V. 1977). However, the bringing together of personnel was only the first small step in what should have been a dynamic drive to progress from an individualistic effort to that of a concerted team approach. In recent years however, there has been increasing controversy about the effectiveness of the team as a unit. PMID- 6905852 TI - Objectively toward curriculum improvement in nursing education in England and Wales. AB - The General Nursing Council (G.N.C.) for England and Wales (circular 77/19/4) is currently influencing schools of nursing to use behavioural objectives, which means immediate implications for the basic training of nurses. As the majority of nurse teachers seek to influence their students' behaviour, there appears to be good grounds for stating clearly what it is they hope their students will achieve. Operationalizing objectives in realistic learning environments will rest on two fundamental assumptions. First, there must be a clear foundation of integrated theory and practice. Secondly, nurse teachers must be using objectives in the light of clear understanding of objective approaches which are based in a conceptual framework of curriculum theory. PMID- 6905853 TI - Academic gaming in nurse education. AB - This paper describes a study of the usefulness of academic gaming in nurse education. The research has been carried out over the course of 3 years and represents an attempt by a nurse tutor to carry out a study on research lines, during the course of normal working and with a minimum of interference to the normal working of a nurse education department. The study involved psychiatric nurse learners at Winterton Hospital, Sedgefield, Durham and attempted to assess the usefulness of academic gaming by evaluating one academic game which has been designed for nurse learners. This game aims to teach various aspects of the digestive system and digestive processes. The questions which required answers were, can nurse learners learn from academic games? Do they like this method of learning? How does this method compare with other learning methods? Eighty-six learners participated in a test/game/test situation and completed a questionnaire after playing the game. Results suggest that learners can increase their knowledge of the subject by playing the game but it may be most useful as a consolidation method. Learners most often stated that they enjoyed the game and when ranked according to preference, gaming was preferred to film, reading and discussion methods but equally preferred to the lecture method. PMID- 6905854 TI - Nurses' perceptions of the British hospital nursing officer. AB - A major objective of the Report of the committee on senior nursing staff structure (Salmon Report) was to clarify the role of middle-management nurses. This paper analyses the views of 170 nurses in two general, one psychiatric, and one mental subnormality hospital, about nursing officers. A nursing officer was mentioned as the person with most say or influence over them by more nurses of all grades in the two non-general than in the two general hospitals, a difference explained in terms of the greater role of the medical model, and hence the sister consultant relationship in the latter. There were, however, also marked differences between the responses received from staff in the two general and between the two non-general hospitals in the perceived influence of the nursing officer which could not be explained in this way. Analysis of repertory grids suggested more problems in relations with senior nurses overall in the general hospitals. Nurses' descriptions of relationships with superiors suggested that nursing officer superiors were seen more as 'socio-emotional' whilst sisters and charge nurses were seen as 'instrumental' leaders. Asked to choose a person who had annoyed them at work, nurses chose a nursing officer more frequently than other grades of nurse, particularly in the non-general hospitals. Reasons for annoyance with a nursing officer included unwarranted interference, destructive criticism, and lack of specialized knowledge. PMID- 6905855 TI - Hospital ward routine--friend or foe? PMID- 6905856 TI - Nursing research information: are nurse educators and practitioners seeking it out? AB - This paper is concerned with if and how nurses are obtaining information on research into nursing. It is based on the results of a wider survey conducted in Northern Ireland in 1979, the aim of which was to assess the degree to which those most concerned with administering, managing, and teaching patient care were managing to obtain and implement information on nursing research. The main sources examined were nursing journals, nurse education curricula, and libraries relevant to nursing. For the purpose of the survey the writer took the view that, in terms of the relationship between nursing and practice, any dichotomy of opinion as to what nursing research is, or is not, is largely semantic. It was decided, therefore, to adopt the holistic approach to the term 'nursing research' as supported by Treece & Treece (1977) who claimed that 'Nursing Research includes the breadth and depth of the discipline of nursing, the rehabilitive, therapeutic and preventive aspects of nursing, as well as the preparation of practitioners and personnel involved in the total nursing sphere. PMID- 6905857 TI - The role of immunoglobulins in alternative pathway activation by zymosan. II. The effect of IgG on the kinetics of the alternative pathway. PMID- 6905858 TI - Implementing a reality shock program. PMID- 6905859 TI - A classification system to meet today's needs. AB - Patient classification systems hold the promise of providing nursing services with objective and scientific means to identify acuity levels and project staffing requirements. Nursing administrators have an obligation to base nurse staffing on objective documentation. To ensure the cooperation of nursing staff, they must make the classification system meaningful to staff and patient care goals. A classification system based on accurate and objective assessment of patient acuity levels will enable administrators to use their most valuable resource--their nursing staff--efficiently and effectively. PMID- 6905860 TI - Evaluating research requests: a model for the nursing director. PMID- 6905861 TI - Stress and the critical care nurse reaffirmed. PMID- 6905862 TI - Selecting a doctoral program for a career in nursing. PMID- 6905863 TI - Unifying education and practice: one medical center's design. Part I. PMID- 6905865 TI - Application of good manufacturing practice regulations to investigational biologic products. PMID- 6905864 TI - Validation studies of the Fostoria infrared tunnel sterilizer. PMID- 6905866 TI - Freeze drying: past, present and future. PMID- 6905867 TI - The effect of chamber pressure on heat transfer in the freeze drying of parenteral solutions. PMID- 6905869 TI - Recovery of biological indicator organisms after sublethal sterilization treatment. PMID- 6905870 TI - A study of the phase transitions in frozen antibiotic solutions by differential scanning calorimetry. PMID- 6905868 TI - Implementation and automation of a particle detection system for parenteral products. PMID- 6905871 TI - Bioavailability of parenteral drugs I. Intravenous and intramuscular doses. PMID- 6905872 TI - Changes of kallikrein and serotonin in plasma during and after open-heart surgery. AB - Plasma kallikrein activity and plasma serotonin were studied during and after open-heart surgery in 15 patients with extracorporeal circulation and in 15 patients with surface-induced deep hypothermia. Following results were obtained: 1) Plasma kallikrein activity which reflects the activation of the kinin system, showed no significant change during extracorporeal circulation, and significantly increased three hours after the termination of perfusion. However, there was no significant difference in plasma kallikrein activity between the patients with and without low cardiac output syndrome (LOS). In surface-induced deep hypothermia, plasma kallikrein activity showed no significant change during and after operation. 2) Plasma serotonin significantly decreased during both extracorporeal circulation and hypothermia. Moreover, there was no significant difference in plasma serotonin between the patients with and without postoperative LOS or pulmonary hypertension. It is assumed that plasma serotonin may not play an important role in regulating blood pressure during or after open heart surgery with either extracorporeal circulation or surface-induced deep hypothermia. PMID- 6905873 TI - [Development of perinatology and its future prospect]. PMID- 6905874 TI - [The role of the midwife in the perinatal care team. Discussion]. PMID- 6905877 TI - [East Germany and her system of maternal and infant care]. PMID- 6905876 TI - [Studying nursing of newborn infants - a viewpoint of a new nursing graduate]. PMID- 6905875 TI - [Progress in the treatment and nursing of premature infants - education in nursing of premature infants]. PMID- 6905878 TI - [Visiting practicing midwives. 38. Midwives at Yaeyama, Okinawa: Isolation of midwives in an island]. PMID- 6905880 TI - [My activities as a midwife at a public health clinic]. PMID- 6905879 TI - [Regional maternal and child health care and the role of midwives. Recommendations for allocation of a midwife at a public health clinic - the opinion by the Tokyo Branch of Midwifery Section, Japan Nursing Association]. PMID- 6905881 TI - [Progress of a maternal and child health study group in Shibuya-ku]. PMID- 6905882 TI - [Lessons in clinical training in regional maternal and child health care]. PMID- 6905883 TI - [Health consulting service by a practicing obstetrician]. PMID- 6905884 TI - [Puerperal health instruction formulated on the basis of a survey on the daily problems of puerperal patients]. PMID- 6905885 TI - [Regional maternal and child health care in Niigata Prefecture--the current status and future prospect. Discussion]. PMID- 6905886 TI - [Medical scope. Premature labor and bacterial infection]. PMID- 6905887 TI - Students participate in the legislative process. PMID- 6905888 TI - Quality assurance in nursing: what others are doing. PMID- 6905889 TI - Advanced nursing programs: an overview of the University of Kansas. PMID- 6905890 TI - [Systemic arterial hypertension characteristics in bronchial obstruction]. PMID- 6905891 TI - Planning and implementing health screening programs. PMID- 6905892 TI - The experts rate important features and outcomes of sex education programs. PMID- 6905893 TI - Daily, dry toothbrushing in kindergarten. PMID- 6905894 TI - Smoking Sam goes to school. PMID- 6905896 TI - Adolescent homosexual behavior and the health educator. PMID- 6905895 TI - Practical multiple-choice exams. PMID- 6905897 TI - The impact of bronchial asthma on school attendance and performance. PMID- 6905898 TI - What do teens know about the facts of life? PMID- 6905899 TI - When adolescent mothers return to school. PMID- 6905900 TI - Linking health education content with classroom group development: a suggestion for planning. PMID- 6905901 TI - [Sex (2). The neurophysiological mechanism of sex]. PMID- 6905902 TI - [Bedside conference in pediatric nursing (11). Nursing of children with congenital heart diseases. (4)]. PMID- 6905903 TI - [The nursing system: a vision for future reform (1)]. PMID- 6905904 TI - [The concept of the curriculum in nursing education and new trends--with adult nursing as an example]. PMID- 6905905 TI - [Theories of curriculum evaluation (2)]. PMID- 6905906 TI - [Evaluation of clinical training in the basic nursing course--with special reference to planning the nursing process]. PMID- 6905907 TI - [Emergency care at a ward]. PMID- 6905908 TI - [Nursing capability expected at the sudden exacerbation of the clinical condition of the patient]. PMID- 6905909 TI - [Role of the nurse at the sudden change in the patient's condition. Emergency treatment of the patient and patient care team--the present status at the circulatory disease ward of our hospital]. PMID- 6905910 TI - [Hospital training in emergency treatment]. PMID- 6905911 TI - [Criteria of nursing action at the sudden change in patients--a medicolegal aspect]. PMID- 6905912 TI - [A survey on the attitude of nurses towards X-ray therapy]. PMID- 6905913 TI - [An aspect of emergency care--problems concerning members of the emergency rescue team and their nursing activities]. PMID- 6905914 TI - Perceptions of time by multiparous women in relation to themselves and others during the first postpartal month. PMID- 6905915 TI - Update 1980: new developments in high blood pressure. PMID- 6905916 TI - Hypertension: five-year detection and follow up report. PMID- 6905917 TI - The prevalence of high-level methicillin resistance in multiply resistant hospital staphylococci. AB - This study was prompted by observing in the summer of 1975, five lethal septicemias caused by methicillin resistant staphylococci. Among the 17 initial S. aureus strains, only 36% were killed at 250 micrograms per ml of methicillin. One phage type of S. aureus predominated (85, group III). Methicillin resistance was found in 17 of 102 S. aureus and in 28 off 102 S. epidermidis septicemias; the mortality among methicillin resistant S. aureus cases was 52.9%, corresponding to 39.3% for S. epidermidis sepsis. Antibiograms revealed methicillin resistance in 59/400 S. aureus and 94/400 S. epidermidis isolates. Cross-resistance to other drugs was common. It is concluded that the emergence of methicillin and gentamicin-tobramycin resistance among hospital staphylococci represents a serious, persistent problem. Certain microbiologic characteristics of these resistant strains differ from results heretofore reported by others. PMID- 6905918 TI - How to get through the organizational maze? PMID- 6905919 TI - Violet: a case of sensory deprivation. PMID- 6905920 TI - Collective bargaining: a tool for professional growth. PMID- 6905921 TI - The equal rights amendment. PMID- 6905922 TI - ICN: its international role. PMID- 6905923 TI - Students in the operating department: an examination of some factors governing their choice of career. PMID- 6905924 TI - Ability of kallikrein to generate angiotensin II-like pressor substance and a proposed 'kinin-tensin enzyme system'. AB - Pig pancreatic kallikrein liberates kallidin from kininogen, whereas trypsin releases bradykinin. Recently, both kallikrein and trypsin have been reported to convert inactive plasma renin to active renin. However, we found that at pH 6.0, trypsin generated an angiotensin II-like pressor substance from human plasma protein in the absence of converting enzyme. This has been isolated and found to have the same amino acid composition as angiotensin II. Thus, in vitro trypsin can directly liberate both the depressor, bradykinin, in weak alkaline conditions, and the pressor, angiotensin II, at weakly acidic pH, from the appropriate substrates. We have now investigated whether kallikrein--a serine protease like trypsin--also generates a pressor substance at weakly acidic pH. Our results demonstrate that it does. We therefore suggest that kallikrein may be involved in a direct link between the pressor and depressor systems and we propose the term 'kinin-tensin system' for this sort of one-enzyme system capable of generating both depressor and pressor substances. PMID- 6905925 TI - CE for the educator role of nursing faculty. PMID- 6905927 TI - Health policy in the nursing curriculum: why it's needed. PMID- 6905926 TI - Credit-for-faculty practice model: a proposal. PMID- 6905930 TI - Hospice nursing. Walking a fine line. PMID- 6905929 TI - Career guide: who wants to think about an unsatisfactory evaluation? PMID- 6905931 TI - Sharing: breaking the ice. PMID- 6905932 TI - Reporting an incompetent co-worker--and protecting your patients. PMID- 6905933 TI - Abdominal assessment. A blending of science and art. PMID- 6905934 TI - Understanding endorphins: our natural pain relief system. PMID- 6905935 TI - New life for lungs...through incentive spirometers. PMID- 6905936 TI - Understanding the signs of intracranial pressure. A bedside guide. PMID- 6905937 TI - Appearances can be deceiving...in Mr. Langley's case, they were shocking, too. PMID- 6905938 TI - Helping the patient who wants to die at home. PMID- 6905939 TI - When you face the alcoholic patient. PMID- 6905940 TI - Need to track your patient's heart? Try telephones and tape recorders. PMID- 6905941 TI - Test your knowledge of preventing and treating septic shock. PMID- 6905942 TI - A clean, quick way to administer a barium enema through a colostomy. PMID- 6905943 TI - A key to compliance. Systematic teaching to help hypertensive patients follow through on treatment. PMID- 6905944 TI - Diagnostic tests: preparing your patient physically for an esophagogastroduodenoscopy. PMID- 6905946 TI - Mothers and children in society. PMID- 6905948 TI - The changes that take place during pregnancy. PMID- 6905947 TI - Adjustment of women to motherhood. PMID- 6905945 TI - Mother and newborn: introduction. PMID- 6905949 TI - What do we know in advance? PMID- 6905950 TI - Antenatal care in Britain. PMID- 6905951 TI - Neonatal abilities. PMID- 6905952 TI - Signs and symptoms of late pregnancy and the onset of labour. PMID- 6905953 TI - Normal labour and the midwife's role. PMID- 6905954 TI - Abnormal labour and pain relief. PMID- 6905955 TI - Recent changes in labour management. PMID- 6905956 TI - Post-natal care. PMID- 6905957 TI - Careers in nursing: midwifery. PMID- 6905958 TI - Handicap, bereavement and the midwife. PMID- 6905959 TI - Welfare rights and organizations. PMID- 6905961 TI - District nursing in the 1980s. PMID- 6905960 TI - Service planning--an essential role of the nurse. PMID- 6905962 TI - Thoughts on "cot sides". PMID- 6905963 TI - Your lifestyle: a jog in the right direction. PMID- 6905964 TI - More emphasis on attitude. PMID- 6905965 TI - Nursing officers and supplies. PMID- 6905966 TI - You are the guardians of human life. PMID- 6905967 TI - [Evolution--promotion--spirituality]. PMID- 6905968 TI - Scientific and humanistic elements in the formation of nurses. PMID- 6905969 TI - Profile of the christian nurse and her responsibility towards the actual society(Puerto Rico). PMID- 6905970 TI - Christian spirituality challenge to the nurse. PMID- 6905971 TI - Neonatal necrotizing enterocolitis associated with penicillin-resistant, toxigenic Clostridium butyricum. AB - The cause of neonatal necrotizing enterocolitis (NEC) is unknown. An association between NEC and clostridial infection has been reported from several centers, but the organisms have not been extensively characterized. Clostridium butyricum was isolated from the peritoneal fluid and cerebrospinal fluid of a neonate with NEC. The organism was resistant to the penicillins, but sensitive to vancomycin. Toxin production was demonstrated. Although the role of clostridial toxins in the pathogenesis of NEC is unknown, clostridial toxins are well established as the causes of two other intestinal diseases (antibiotic-associated pseudomembranous colitis and pig-bel). Further investigation of the role of clostridia in the pathogenesis of NEC and of the use of oral, nonabsorbable antibiotics in the treatment of NEC is needed. PMID- 6905972 TI - Therapeutic tasks: strategies for change. PMID- 6905973 TI - Point--the scatter bed system of care: should psychiatric patients be placed in medical/surgical units? PMID- 6905975 TI - Defining the role and function of the psychiatric nurse as a member of the team. PMID- 6905974 TI - Counterpoint--the scatterbed system of care: should psychiatric patients be placed in medical/surgical units? PMID- 6905978 TI - Health policy: the clinical perspective. PMID- 6905977 TI - Health policy in the nursing curriculum: why it's needed. PMID- 6905976 TI - Implementing health policy in baccalaureate nursing curricula. PMID- 6905979 TI - Speaking out: the views of nurse leaders. PMID- 6905980 TI - Issues in diploma nursing education in the eighties. PMID- 6905981 TI - Health and nursing issues in the eighties. PMID- 6905982 TI - Assuming leadership roles. PMID- 6905984 TI - Recruiting students in the eighties. PMID- 6905983 TI - Preparing graduates in the eighties. PMID- 6905985 TI - Cost containment--a constant concern. PMID- 6905987 TI - Decade assessment: accentuating the positive. PMID- 6905986 TI - Articulation: possibilities and restrictions. PMID- 6905988 TI - Beyond assessment: the tacit dimension in nursing. PMID- 6905990 TI - Work of the Task Force on Competencies. PMID- 6905989 TI - Beyond technology: ethical issues in nursing. PMID- 6905991 TI - Background and findings of the Task Force on Competencies. PMID- 6905992 TI - The impact of technology on patients, providers, and care patterns. PMID- 6905993 TI - Compensating faculty for their clinical practice. PMID- 6905994 TI - Is practice a viable faculty role? PMID- 6905995 TI - Extending home care services: an experiment that failed. PMID- 6905996 TI - Writing a master's thesis. PMID- 6905997 TI - Perishing while publishing: as the authors see it. PMID- 6905998 TI - Perishing while publishing: as the editor sees it. PMID- 6905999 TI - The real vs ideal content in master's curricula in nursing. PMID- 6906000 TI - The systems approach: a basis for course redesign. PMID- 6906001 TI - Symbolic acts and the development of a professional identity. PMID- 6906002 TI - Videotape as an evaluation tool. PMID- 6906003 TI - Undergraduate research. PMID- 6906004 TI - Health care issues as an interdisciplinary course. PMID- 6906005 TI - Public knowledge of hospice care. PMID- 6906007 TI - Continuing education: step two. PMID- 6906006 TI - Minority nurses in the news. PMID- 6906008 TI - Stress and coping in hypertensive and emergency room patients. AB - Stressful life events (SLEs) and coping behavior were compared in 25 emergency room patients with nonserious acute illness and 25 newly diagnosed hypertensive patients. Stress was evaluated with a modified Rahe's SLE questionnaire and coping with a rate scale developed by the primary investigator. Results showed that: ER patients reported significantly more (p < .05) SLEs for one year preceding illness onset, although more hypertensives subjectively rated their stress level as high; ER patients experienced significantly more SLEs in personal and social, home and family, and financial categories; hypertensives experienced significantly more health-related SLEs; age was seen as influencing SLEs; hypertensive patients used significantly more problem-oriented coping methods than did ER patients; hypertensives relied more on religion and physical activity in coping than did the ER group; ER patients more often day-dreamed or used their past experience as a guide for coping with stress; each group rated use of drugs as least important in coping; and educational level proved to be a salient variable affecting coping. PMID- 6906009 TI - Diagnosing boredom and confusion. AB - An interview schedule to determine whether individuals could be diagnosed psychologically as being in a bored, confused, or adaptive state of mind was constructed and tested. Boredom and confusion were viewed as two distinct maladaptive states of mind. Objectivity, reliability, and validity were demonstrated for the interview schedule. The schedule was effective in diagnosing maladaptive and adaptive states of mind in outpatients who sought help at a family practice clinic and in detecting changes from maladaptive states to an adaptive state of mind after four weeks of psychological treatment. PMID- 6906010 TI - The Institutional Review Board: a case study of no-risk decisions in health related research. PMID- 6906013 TI - Committee evolution in a medical center. AB - Development of the Nursing Research Committee in the Mary Hitchcock Memorial Hospital, Hanover, New Hampshire, is described. Six problems were identified, and ways in which the committee solved the problems are discussed. PMID- 6906011 TI - Research program development in a tertiary care setting. AB - The Committee on Clinical Nursing Research was established in April 1979 at the Hospital of the University of Pennsylvania, Philadelphia, not only to encourage clinical nursing research for the provision of optimal care and the development and evaluation of nursing practice, but also to monitor consumer safety vis-a-vis the research effort. The development of the committee and relevant issues are discussed. PMID- 6906012 TI - Nurse involvement in Institutional Review Boards; the service setting perspective. AB - Access to nursing service settings and protection of human subjects for research purposes are facilitated by the institutional review board if nursing is represented on the board and nurses' research protocols are reviewed for scientific merit and human subject implications. A nurse researcher recounts experiences in achieving these goals within a service setting. PMID- 6906014 TI - Effect of therapeutic touch on anxiety level of hospitalized patients. AB - Effect of therapeutic touch on the anxiety of 90 volunteer male and female subjects between the ages of 21 and 65, hospitalized in a cardiovascular unit of a large medical center in New York City, was examined. The dependent variable, state anxiety, was defined as a transitory emotional state of the individual at a particular point and was measured by the Self-Evaluation Questionnaire x-1, developed by Spielberger, Gorsuch, and Lushene. Subjects were administered this tool pre- and postintervention. Three matched intervention groups were formed; each subject received an individual five-minute period of intervention by therapeutic touch, casual touch, or no touch. Subjects who received intervention by therapeutic touch experienced a highly significant (p < .001) reduction in state anxiety, according to a comparison of preposttest means on A-state anxiety using a correlated t ratio. Subjects who received intervention by therapeutic touch had a significantly (p < .01) greater reduction in posttest anxiety scores than subjects who received intervention by causal touch or no touch. PMID- 6906015 TI - Communication patterns and conflict in marital dyads. AB - Responses--pauses, laughter, and interruptions (postulated to be communication techniques of couples with more equal power in decision making) and questions, silence time, and longer decision time (hypothesized to be communication techniques of couples in a dominant-submissive power structure)--of 68 middle class suburban couples who volunteered to take the Inventory of Marital Conflicts were analyzed. Although study hypotheses were not supported, a high intercorrelation was revealed among communication variables hypothesized to be characteristic of power-sharing couples. PMID- 6906016 TI - Selected correlates of job performance of community health nurses. AB - Using a study sample of 32 community health nurses employed by the Visiting Nurse Association of Hartford, Inc., the relationship of selected attribute and environmental variables was studied, and a quantitative rating of the nurses' job performances was developed. A nonhierarchical stepwise multiple regression analysis was used to determine the relationship between job performance and the independent variables: age, education, work experience, five state board licensure examinations, job satisfaction, and leadership behavior. A principal component analysis with Varimax rotation was used to reduce the independent variables to three components: state board examinations, biographical information, and attitude toward the work environment. The raw score model produced a larger multiple correlation (p < .05) than the reduced rank model in the regression analyses. This result was due, in part, to the small sample size in relation to the number of independent variables for the raw score model. However, the rank reduction of the raw scores captured only 38 percent of the variation among the items. PMID- 6906017 TI - Prediction of freshman students' success in a baccalaureate nursing program. AB - The best predictor of achievement in college when cognitive and noncognitive variables were tested in two classes of freshmen nursing students (1975 and 1976) at Wilkes College, Wilkes-Barre, Pennsylvania, was the Aptitude Test for Nursing. Cognitive variables significant in 1975 were mathematics Scholastic Aptitude Test scores and high school rank, while in 1976 arithmetic formulation entered into the regression equations as did the noncognitive variable of conformity. A discrepancy was found between 1975 and 1976 predictor variables of dropping out of nursing. For the 1975 freshman class, science grade point average and the support scale of the Gordon Survey of Interpersonal Values were the best predictors of dropping out of the nursing program; in the 1976 class, nursing GPA alone was the best predictor of dropping out. Although an intercorrelation was noted between science GPA and nursing GPA, the success of predicting dropping out of nursing in relationship to science GPA and nursing GPA appeared to be unstable. PMID- 6906019 TI - Nurses' quality of working life in an HMO: a comparative study. AB - Three dimensions of the quality of nurses' working life in a health maintenance organization--job satisfaction, job tension, and organizational commitment--were studied. Subjects included 50 licensed vocational nurses, 47 registered nurses, and 14 nurse practitioners. Nurse practitioners registered a statistically significant higher level of job satisfaction than RNs and LVNs; RNs registered a statistically significant higher level than LVNs. Nurse practitioners reported more job tension than RNs or LVNs, and RNs reported more than LVNs, but the differences were not significant. Differences among the groups were not significant for organizational commitment, but NPs expressed the highest level of commitment. PMID- 6906020 TI - Parametric statistics and ordinal data: a pervasive misconception. PMID- 6906021 TI - Microbiology. A concern for nursing. AB - As nurses become aware, once again, of the devastating effects of nosocomial infection on the patient in terms of morbidity, permanent disability, mortality, excess hospital costs, and law suits, attention is being directed toward its prevention and control. Florence Nightingale intimated that a person should not become sicker in the hospital after admission than before entry as the result of infection. We still need to heed her admonitions. The other articles in this issue will deal with microorganisms in regard to specific patients, anatomic sites, treatment regimens, and infectious diseases. Hopefully, the reader will be provided with enough information to reduce the nosocomial infection rate on her or his nursing unit to nearly zero. PMID- 6906018 TI - Measurement properties of clinical simulation tests: hypertension and chronic obstructive pulmonary disease. AB - Reliability and validity of two clinical simulation tests were studied, using a multimethod approach. The instruments were originally tested in a project that compared ability of physicians, nurse practitioners, and public health nurses to provide primary care. Reliability was assessed by comparing test scores of the same subjects on two occasions. Validity was assessed by: 1) comparing test scores of two expert panels and of professional health groups (nurses and physicians) with preprofessional groups (nursing and medical students), 2) comparing test contents with authoritative literature on the disease, and 3) analyzing results of test evaluation by all subjects. Subjects of the original project were compared with those in this study. Both tests were found reliable and valid, corroborating the original project's findings that nurse practitioners and physicians are equally proficient in assessment and treatment of health problems. Findings also lend validity to the tests' developmental model and suggest the usefulness of such tests in nursing and medical education. PMID- 6906023 TI - Preventing infection in the catheterized patient. PMID- 6906022 TI - The patient's environment: haven or hazard. AB - The hospital environment is a complex mix of animate and inanimate components that interact in a myriad of ways to alter the normal flora of a patient, become reservoirs for hospital strains, and provide pathways for transmission of potential pathogens to patients, personnel, and visitors. It is increasingly vital that those responsible for medical and nursing care have the knowledge of normal microbial flora, potential pathogenic organisms, and the routes of transmission through direct or indirect contact, air, or vehicles on which to base responsible decisions. To be effective this knowledge must be incorporated into assessments of individual patients which identify risks and hazards and into daily routine activities (such as handwashing) to block or minimize colonization by hospital strains that can lead to nosocomial infection. PMID- 6906024 TI - Decontamination, disinfection, and sterilization. PMID- 6906025 TI - Prevention of nosocomial infection in critical care unit. PMID- 6906026 TI - Maternal infections. Problems and prevention. AB - Prenatal care; proper aseptic technique in labor, delivery, and postpartum areas; and general postpartum hygiene are important factors in preventing nosocomial infections. However, if these infections do occur, they must be promptly recognized and early signs and symptoms reported in order that proper therapy may be instituted. PMID- 6906027 TI - Prevention of infection in the nursery. AB - Most infants are "sterile" when admitted to the newborn nursery. Rapid colonization of microorganisms in the infant then occurs. Colonization of virulent microorganisms can overwhelm the immature local and systemic immunity of a newborn infant. Cannulae, catheters, and assisted ventilation can bypass these fragile defenses. Effective infection control in the nursery attempts to reduce the exposure of the neonate to harmful microorganisms. Important measures include (1) the reduction of bacterial colonization through appropriate care of the umbilical stump and skin of the patient; (2) handwashing before and after contact with a patient; (3) low nurse-to-patient ratios; (4) cohorting of newborn infants; (5) isolation and cohorting of infected babies; (6) good hygiene among personnel; and (7) use of aseptic technique. Neonatal intensive care units have extraordinarily high infection rates. Most infants are on ventilators. Daily decontamination of respiratory equipment is essential. Regular monitoring of endotracheal cultures is useful, particularly when bacteria that are resistant to multiple antibiotics emerge. PMID- 6906029 TI - Control and prevention of infection on hemodialysis units. AB - The maintenance hemodialysis unit, an area of special infection control concern, was discussed. An approach was presented which illustrates that effective control and prevention measures evolve from an organized method of identifying the pertinent data, defining the problems, creating workable and reasonable control measures, implementing the measures, and then evaluating their effectiveness. Nurses represent the largest percentage of direct patient care practitioners. Since infection control and prevention measures affect them directly, nurses must assume a predominant role in the development, application, and evaluation of these measures. PMID- 6906031 TI - Research Orientations in nursing. XVIII. Is my hypothesis statistically significant--Part II. PMID- 6906030 TI - Standard versus status. PMID- 6906028 TI - Prevention of infection in extended care facilities. PMID- 6906032 TI - The teacher and the child. PMID- 6906033 TI - Prospects for leprosy control in the eighties. PMID- 6906034 TI - The suicidal client: philosophical bases for nursing intervention. PMID- 6906036 TI - Employer retaliation: the myth and the reality. PMID- 6906037 TI - Responses of systemic vascular smooth muscle to hypoxia. AB - The rapidity and extent of hypoxic relaxation of vascular smooth muscle (VSM) from different systemic vessels is relevant to the study of mechanisms of vasodilation in different vascular beds. Variations between sites may also assist understanding of the link between oxygen tension and mechanical activity, which has been shown not to be a simple deprivation of aerobic processes. Strips of rat portal vein (RPV), rabbit ear artery (REA) and rabbit common carotid artery (RCC) were studied under isotonic conditions, contracted by 10(-6) noradrenaline (NA). Reduction of Po2 to less than 3KPa during NA constraction led to relaxation which was rapid and 90% complete in RPV, rapid and 60% in REA: the relaxation began when tissue Po2 was decreasing and was not lower than 5.5 K Pa. RCC responded slowly and only some strips relaxed. The rapidity and magnitude of relaxation for each type of vessel was comparable to that produced by removal of external calcium. Also for any one type of VSM the response to NA was abolished or diminished to a similar extent by preliminary exposure to hypoxia, or by preliminary removal of calcium. Preliminary hypoxia diminished 50 mmol.1(-1) K+ contractions as much as it diminished NA contractions. Preliminary 1-2 hour exposure to hyperoxia diminished the subsequent relaxant effect of hypoxia. Inhibition of glycolysis (iodoacetic acid) had no effect on normoxic NA contraction or on hypoxic relaxation, but prevented or diminished the subsequent recovery on reoxygenation. Low oxygen tension appears to act in VSM as though it interferes with net influx or utilisation of external calcium. PMID- 6906038 TI - Physical fitness training in patients. AB - Patients recovering after heart valve surgery are not in an optimum state of 'cardiorespiratory fitness'. To examine this proposition a controlled trial of physical training was undertaken in patients recovering from the replacement of a single heart valve. Patients were allocated to a test or control group two weeks after operation. Each patient performed a submaximal exercise test at entry, and twelve and twenty-four weeks after this test. The Canadian Air Force exercise programme was undertaken by the test group, while the control group continued normal activities for the twenty-four weeks between the first and last exercise test. A regression line of submaximal heart rate on oxygen consumption was calculated from the data of each exercise test in each patient. Alterations in this line were used as an 'index' of changes in 'cardiorespiratory fitness'. The individual results showed a consistent improvement in 'cardiorespiratory fitness' over the first 12 weeks in both groups. Only patients in the test group continued to improve between 12 and 24 weeks. Thus the exercise programme modified the recovery of 'cardiorespiratory fitness' after operation. A physical fitness rehabilitation programme may help these patients gain maximum benefit from correctiv surgery. PMID- 6906039 TI - Diuretic effect of intraventricular and intravenous infusions of noradrenaline in conscious sheep. AB - Infusion of noradrenaline at rates between 32-160 nmol.min-1 for 30 min into one lateral cerebral ventricle of conscious sheep caused a diuresis which was accompanied by negative solute-free water reabsorption and which lasted for 90 120 min. The range of noradrenaline infusion rates used reflects differences between individual animals in the rate of infusion necessry to cause diuresis. Intracerebroventricular (ICV) infusion of noradrenaline at half the diuretic rate caused no significant changes in urine flow. The diuresis induced by ICV noradrenaline infusion was prevented by concurrent ICV administration of the alpha-adrenergic antagonist, phentolamine, but was not prevented by concurrent ICV administration of the beta antagonist, propranolol, or by concurrent intravenous infusion of phentolamine. Intravenous infusion of noradrenaline at rates that were diuretic by ICV infusion caused a diuresis of approximately 30 min duration which coincided with the period of intravenous noradrenaline infusion. This diuresis was prevented by concurrent intravenous infusion of phentolamine. These results were interpreted as indicating that the higher rates of ICV infusion of noradrenaline caused the prolonged water diuresis by acting at a site in the brain and, thereby, inhibiting the release of endogenous vasopressin. ICV infusion of noradrenaline at all rates was followed by a reduction in mean arterial blood pressure and pulse pressure with variable changes in heart rate and by depression of the rates of renal clearance of PAH, potassium and total solute. PMID- 6906041 TI - Identifying talented health administration students: a look at academic criteria. AB - The objective of this study was to examine the relationships of undergraduate academic and admission test performance with graduate academic performance. Results could aid in selecting health service administration students in the future. The sample included 139 students (40 women and 99 men) entering seven health services administration programs during the fall of 1975 and graduating during the spring and summer of 1977. Participating programs were located in the Midwest, Northeast, South, and West Coast. Independent variables included undergraduate academic performance and admission test scores, while the dependent variable was graduate academic performance. Correlation analyses revealed that: (a) the verbal and quantitative subtest scores of the GRE were related to most aspects of graduate academic performance for men but only to selected aspects for women, (b) performance on the MAT was related to women's graduate academic performance in quantitative courses, and (c) men's and women's composite undergraduate grade point average was not related to composite graduate grade point average. These findings suggest that some of the standardized tests presently employed as admission screening devices should be used judiciously. PMID- 6906040 TI - The effects of colchicine on milk secretion, mammary metabolism and blood flow in the goat. AB - Mammary function in the conscious goat was studied during colchicine-induced depression of milk secretion in one mammary gland. Milk yield of the treated gland was reduced to approximately a quarter of previous, while there were significant increases in afternoon milk yield from the untreated glands on the 2nd and 3rd days after treatment in goats in late lactation. Milk composition in the untreated glands was not significantly affected. In the treated gland, milk [Na+], [Cl-], [citrate] and [protein] increased while [K+] and [lactose] decreased, although the time course of these changes differed; milk [fat] was unaffected. Mammary extractions ((A-V)/A) of glucose, acetate and most amino acids were significantly decreased during the period of maximal inhibition of secretion. There were no significant changes in arterial plasma concentrations of glucose, acetate or any essential amino acids. In another series of experiments, mammary blood flow increased and then returned to normal after colchicine treatment even though milk yield and mammary glucose uptake decreased markedly; oxygen uptake was not significantly affected. The results are discussed in relation to the actions of colchicine on the mammary secretory cell, to the normal control of mammary blood flow and to the mechanism of compensation by the untreated gland. PMID- 6906043 TI - Perceived choice, social interaction, and dimensions of moral of residents in a home for the aged. AB - In a study of 50 residents in a home for the aged, the relationships of health at relocation, choice in relocation, income, perceived choice within an institutional environment, and social interaction to four indices of morale were examined in hierarchical multiple regression designs. The theoretical concept of decisional control (i.e., perceived choice) guided the investigation. Significant multivariate effects were found for all dimensions of morale: agitation, attitude toward own aging, lonely dissatisfaction, and a combined morale index. Choice within the institution and social interaction were the major contributors to these significant multivariate relationships, but income was also influential in analysis of the attitudinal and combined morale indices for a subsample. Retrospective measures of health at relocation and choice in relocation were unstable in their contributions to overall multivariate relationships. Relationships of age, recency of loss of a significant other, and length of residency to morale were explored and found not to be significant. Results are discussed against the background of theoretical expectations, and avenues for future research are identified. PMID- 6906042 TI - Women's roles and illness episodes: a prospective study. AB - As more women enter the labor force, their roles proliferate. The purpose of this study was to determine whether proliferation of roles would have a deleterious effect on the women's health. A group of 96 women completed a family health diary for 3 weeks which included an estimate of stress level typical of the family on each day, the measures taken by the family to maintain health, an estimate of how each family member felt, whether or not behavior restriction was necessary, and any symptoms or complaints. An illness episode was considered to be any continued sequence of days during which health complaints were recorded in the health diary. The mean number of illness episodes for the 3-week diary-keeping period was 3.23 (SD = 1.50). Role proliferation did not correlate with the number of illness episodes (Spearman's rho = -.115 p < .132). The variables that best explained the variance in the number of illness episodes were the number of children and role reinforcement, both of which had modest negative effects on number of illness episodes; together they explained 11.3% of the variance. It was concluded that the number of episodes of illness women experience is a function of the compatibility of a woman's other roles with being ill and with the support available to her performing her roles. PMID- 6906044 TI - Concurrent validity of three self-report measures of assertiveness. AB - The relative validity of three self-report measures of assertiveness was assessed by correlating the scored obtained by 88 student nurses with peer and faculty ratings of assertiveness. Self-reported assertiveness failed to predict frequency of class participation within a subsample of 48 students. Type of instructional setting, however, did exert a significant effect on class participation. PMID- 6906045 TI - Comparison of glucosuria in the first- and second-voided specimens and the time of day as tested by four commercial testing products. AB - The questions addressed in this study were whether testing first- and second voided urine specimens yielded different results and whether selected commercial testing product (Clinitest 2 drop, Clinitest 5 drop, Tes-Tape, and Keto-Diastix) yielded similar estimates of glucosuria. Twenty adult diabetic experiencing glucosuria served as subjects. First- and second-voided specimens were collected before meals and before retiring. Data were analyzed using a three-way ANOVA with repeated measures on all factors. The findings indicated significant main effects for product type, F (3,57) = 7.61, p = .0004, and time of day, F (3,57) = 8.60, p = .0002. The main effect for first- and second-voided specimens did not approach significance. PMID- 6906046 TI - [Importance of the antibiogram in Streptococcus pneumoniae (pneumococcal) infections]. PMID- 6906047 TI - [Bf groups in ankylosing spondylitis]. AB - The phenotypes Bf were studied in 50 patients (42 men and 8 women) with definite ankylosing spondylitis and in certain of their relatives. The alleles BfF and BfS were most frequently encountered and the rare allele BfF1 in one case only. There may exist a preferential transmission of the haplotype HLA B27- Bf S. In 11 patients without B27 antigen, the distribution of the phenotypes was similar to that in a control group. It is probable that the locus Bf cannot be used as a preferential marker for ankylosing spondylitis. PMID- 6906048 TI - [Taking social responsibility for tuberculous patients]. PMID- 6906049 TI - [Farms for the city's children]. PMID- 6906050 TI - [Alcohol; strange sickness]. PMID- 6906051 TI - [Aides to assist in the home]. PMID- 6906052 TI - [The hospital, the nurse and waste]. PMID- 6906054 TI - [Bandages and dressings]. PMID- 6906053 TI - [Inventories]. PMID- 6906055 TI - [And dying of old age...]. PMID- 6906057 TI - [A hematology center in the mountains]. PMID- 6906056 TI - [The Americans in Paris: putting daily actions into words]. PMID- 6906058 TI - [A roof for social promotion]. PMID- 6906059 TI - [Renaissance of bioclimatic architecture]. PMID- 6906060 TI - [A municipal initiative: the Health Center of Goussainville]. PMID- 6906061 TI - [Get up and walk]. PMID- 6906064 TI - [Make your purchases in the hospital]. PMID- 6906063 TI - [When a simple reception turns into quality]. PMID- 6906062 TI - [Tuberculin skin reactions]. PMID- 6906065 TI - [Nurses, one of the support of a new health policy]. PMID- 6906066 TI - [The psychiatric nurse tomorrow]. PMID- 6906067 TI - [Pocket computers in the service of patients]. PMID- 6906068 TI - [Foam for bedsore prevention]. PMID- 6906070 TI - [Helping to live - helping to grow old. Interview by M. Clave]. PMID- 6906069 TI - [Alexander, Natalie, Patrick, Franck, and the others]. PMID- 6906072 TI - [The health and social professions: 8th stage in the Tour de France of major problems in Social Security]. PMID- 6906071 TI - [Starting out with good feet]. PMID- 6906075 TI - [The price of the public hospital system]. PMID- 6906074 TI - [A nurse from Quebec reflects on her profession]. PMID- 6906073 TI - [Nurses and infants]. PMID- 6906077 TI - [If glycemia is calculated for me]. PMID- 6906078 TI - Urinalysis: the physical and chemical examination. PMID- 6906076 TI - [Conquering alcoholism in France]. PMID- 6906079 TI - Environmental causes of animal diseases? PMID- 6906080 TI - Amputation of canine rear limb using nerve blocks. PMID- 6906081 TI - Autoimmune hemolytic anemia in sibling cats. PMID- 6906083 TI - Osteochondritis dissecans of the shoulder joint: its surgical treatment. PMID- 6906082 TI - Acquired achalasia: a case report. PMID- 6906084 TI - Idiopathic congestive cardiomyopathy in giant breeds of dogs. PMID- 6906085 TI - Ampicillin sodium (amp-equine) as a parenteral antibiotic for horses. PMID- 6906086 TI - A data base for abdominal pain--2. PMID- 6906087 TI - Percutaneous arterial catheterization in the horse. PMID- 6906088 TI - Intrauterine aspiration of amniotic fluid in a chimpanzee. PMID- 6906090 TI - Food-animal regional anesthesia. Bovine blocks: ocular. PMID- 6906089 TI - Early detection of sickness in feedlot cattle: a planned approach. PMID- 6906091 TI - Exotic Newcastle disease diagnosed in pet birds in 14 states. PMID- 6906092 TI - Screwworm diagnosed in a sheep in Texas. PMID- 6906093 TI - [Indices of components of the kallikrein-kinin system of the blood of healthy full-term and premature infants during the first 3 months of life]. PMID- 6906094 TI - [Effect of physical activity on the state of the kinin system and atherogenesis]. AB - Hydrocortisone-induced hyperlipemia was inhibited by physical loading in trained dogs and rabbits. Hyperlipemia simultaneously with activation of the kinin system was noted in physically untrained animals after the hormone treatment. At the same time, the patterns of lipid metabolism and of the kinin system components approached to the normal values in the trained animals. Importance of the phenomenon found for genesis of atherosclerosis is discussed. PMID- 6906095 TI - [Effectiveness of commercial polyvalent proteinase inhibitors. Use of gordox in vascular surgery]. AB - Effect of hordox on activity of the kallikrein-prekallikrein system was studied in blood plasma of patients with stenosis of abdominal aorta during the reconstructive operation and in patients with septic complications after the open heart operation. These impairments were accompanied by a distinct increase in kallikrein activity with simultaneous decrease in prekallikrein content, suggesting activation of the kininogenase system; the kallikrein activity was normalized in patients treated with the inhibitor. The highest efficiency of the inhibitor was observed in patients with stenosis of abdominal aorta; in patients with septic complications it was 4-fold less effective. The data obtained suggest that inhibition of the blood plasma kininogenase system correlates with restoration in these patients. The results, obtained in study of the inhibitor efficiency in vitro and in vivo, may be used for calculation of therapeutic doses of the proteinase inhibitors. PMID- 6906096 TI - Electrolytes across the age continuum: implications for the practicing nurse. PMID- 6906098 TI - Implications of social, political and economic changes for nursing and nursing organizations. PMID- 6906097 TI - The impact of social, political and economic changes on voluntary organizations. PMID- 6906099 TI - Experimental pulmonary emphysema: its induction in rats by leuko-elastase extracted from purulent sputum. AB - Pulmonary emphysema was induced in rats by leuko-elastase extracted from purulent sputum, with the aim of throwing light on the part played by the elastolytic activity in the pathogenesis of pulmonary emphysema. A brief review of the pertaining literature is presented. PMID- 6906100 TI - Professional obligations and nursing workloads: who speaks for the staff nurse? PMID- 6906101 TI - Brain edema factors: current state with particular reference to plasma constituents and glutamate. PMID- 6906103 TI - Drug interactions and digitalis toxicity. PMID- 6906102 TI - Stalls in the therapeutic process. PMID- 6906104 TI - Growing more balmy each day--love, Mom. PMID- 6906105 TI - Independent nurse project in a VNS. PMID- 6906106 TI - Gallbladder disease: current trends and treatments. PMID- 6906107 TI - Using words without sound. PMID- 6906108 TI - Giving intravenous chemotherapy at home. PMID- 6906109 TI - Nurses united! One staff's decision to strike. PMID- 6906115 TI - Packaging the package. PMID- 6906110 TI - When the baby is sick and the mother's concerns are ignored. PMID- 6906112 TI - The transient man. PMID- 6906113 TI - Responding to the malpractice crisis. The legal side. PMID- 6906111 TI - The value of life-by what standard? PMID- 6906114 TI - Quick assessment of hemiplegics' functioning. PMID- 6906116 TI - Professional nurturance: preceptorships for undergraduate nursing students. PMID- 6906118 TI - "How can I get a job on Capitol Hill?". PMID- 6906117 TI - Dealing with feelings. Managing anxiety. PMID- 6906119 TI - The nurse as admission evaluator. PMID- 6906120 TI - New concepts in understanding congestive heart failure. Part 1: how the clinical features arise. Programmed instruction. PMID- 6906121 TI - Dilemmas in practice: to tell or not. PMID- 6906122 TI - Nurses' solutions for nursing's crisis. PMID- 6906123 TI - Why nurses leave nursing and what can be done about it. PMID- 6906124 TI - Teaching patients about adrenal corticosteroids. PMID- 6906125 TI - Toxic shock syndrome. PMID- 6906126 TI - How to work with a crock. PMID- 6906127 TI - Current research in ophthalmic electron microscopy. PMID- 6906128 TI - The development of the irido-corneal angle in the chick embryo. AB - The iridocorneal angle of the chick embryo was examined by scanning electron microscopy from the 7th day to the 19th day of development. The mesodermal tissue situated between the corneal endothelium and the iris differentiated into trabecular cells. These cells formed a strip on the 9th day and enlarged on the 13th day to form long cellular fibres. The trabecular meshwork was recognizable on the 15th day and reached full development only on the 19th day. The development of the trabecular meshwork was probably much earlier than is usually described. It began with differentiation of the corneal endothelial cells and these cells acquired a multipolar cell body with long cellular processes. The last stage is probably regulated to avoid an abnormal development of the angle structure. These results can be correlated with those obtained in the morphological examination of the structure of the angle in congenital glaucoma and the "cleavage syndrome" of the anterior chamber. PMID- 6906129 TI - Immunoelectronmicroscopical investigations on isolated collagen fibrils. AB - Isolated collagen fibrils treated with type-specific antibodies can be stained using a peroxidase-antibody complex. The staining pattern of the fibrils with this peroxidase-antibody complex is demonstrated and compared with the normal negative staining pattern of the fibrils. The possible binding sites of the anticollagen antibodies on the fibrils is also discussed. PMID- 6906130 TI - Combined macular dystrophy and cornea guttata: an electron microscopic study. AB - Four cases of macular dystrophy in siblings were studied, 2 brothers and 2 sisters (49, 52, 55, 57 years old). The two youngest had an associated cornea guttata. We performed histologic, transmission, and scanning electron microscopic studies, and in addition a morphometric analysis of Descemet's membrane and of guttata excrescences. Previous studies have been confirmed and the problem of the relationship between the two conditions of macular dystrophy and guttate excrescences is emphasised. PMID- 6906132 TI - Preliminary observations on human trabecular meshwork cells in vitro. AB - This report presents our preliminary observations on the trabecular meshwork from human eyes up to 5 days post-mortem in tissue culture. Satisfactory primary cultures were obtained from about 20% of the 423 explants which were investigated. The period prior to growth was from 4 days to 4 weeks and from the appearance of the initial outgrowth it took 25 to 30 days to reach maximum cellular spread within the culture chambers. The progress of the explant and the spreading of the trabecular meshwork cells was monitored by phase-contrast microscopy, time-lapse cinephotomicrography, light microscopy, transmission electron microscopy, scanning electron microscopy and autoradiography (using tritiated thymidine). On the basis of their ultrastructural appearance the cultured meshwork cells seems to be metabolically active. Their cytoplasm contained abundant rough endoplasmic reticulum, many mitochondria, a well developed Golgi apparatus and many coated and uncoated micropinosomes. However, even in short-term culture the trabecular meshwork cells had adapted to the artificial environment of our system and no longer resembled "normal" trabecular meshwork cells as seen in vivo. Since trabecular meshwork cells can quickly adapt their morphology in a culture environment and because the adult human meshwork contains a significant population of non-trabecular cells, the value of long term culture as a means of investigating the cellular activity of the normal and glaucomatous outflow system must be open to question. PMID- 6906131 TI - Age related changes in extracellular materials in the inner wall of Schlemm's canal. AB - An electron microscopic investigation was conducted to study the extracellular materials of the endothelial meshwork in the human outflow apparatus. A quantitative analysis was made to determine the changes which occur with age. Tissue from 20 cases, ages 4 months to 80 years, was examined. A morphometric technique which utilised a grid of 100 random points was used to estimate the percentage area of extracellular components in the endothelial meshwork. It was found that while the percentage area occupied by amorphous ground substance and fibrillar material decreased with age, the percentage area occupied by the electron-dense component increased. Variation in distribution of these components was noted both between cases of similar age and also within one section. A qualitative description of other changes in the trabecular meshwork is given, and the limitations of the technique are discussed. PMID- 6906133 TI - Transcellular aqueous humor outflow: a theoretical and experimental study. AB - When the aqueous humor passed through the transcellular channels of the inner wall endothelium of Schlemm's canal the flow was estimated to be very slow and viscous (Reynolds' number about 10(-3)). It was found to be accurate to treat this extreme flow situation with conventional hydrodynamic formulae without specific corrections. Four different principal configurations of the transcellular channels were investigated. The theoretical calculations yielded results in good agreement with those obtained from the experimental model studies. Where deviations occurred they were probably explained by a radial flow component, which was not incorporated in the theoretical formulae applied. A spherical channel configuration was considered most similar to the in vivo situation and this yielded experimental resistance values half those of previously applied theoretical methods. Using previous morphological data the present results indicated that less than 5% of the total resistance to aqueous humor outflow was located in the inner wall endothelium in normal human eyes, and about 10% in cynomolgus monkey eyes at normal intraocular pressures. PMID- 6906134 TI - Increased vascular permeability in the rabbit iris induced by prostaglandin E1. An electron microscopic study using lanthanum as a tracer in vivo. AB - Prostaglandin E1 (PGE1) (25 micrograms) was applied topically to the eyes of albino rabbits, and lanthanum was used as an electron microscopic tracer to study possible vascular permeability changes in the iris of these eyes. Lanthanum was injected directly into the blood circulation 15 min after application of the PG, and the eyes were enucleated 30 to 60 min later. PGE1 was found to induce increased vascular permeability. Heavy deposits of the tracer were found in the walls of iridial venules, especially between the endothelium and its basement lamina. The highest concentration of lanthanum was found in close relation to the interendothelial clefts. Occasionally, gaps between neighbouring endothelial cells were observed. In control eyes, not treated with PG, no extravasation of the tracer was found. The study indicates that the iridial blood vessels contribute to the production of the plasmoid aqueous humour induced by PGE1 in the rabbit eye. PMID- 6906135 TI - Frozen resin-cracking, dry-cracking and enzyme-digestion methods in SEM as applied to ocular tissues. AB - Frozen resin-cracking and dry-cracking methods, as well as enzyme digestion by trypsin, hyaluronidase and collagenase, were applied to ocular tissues to study the usefulness of these methods in scanning electron microscopy (SEM). The methods are described and compared, and their advantages and limitations indicated. It is concluded that all the methods presented can give extended information in SEM, but that it is necessary to be familiar with the artifacts produced. PMID- 6906139 TI - Recovery of the rabbit retina after light damage (preliminary observations). AB - The retinae of anaesthetised Dutch rabbits were exposed to one of two intensities of white light for a period of 1 h. After exposure the animals were allowed to recover for various periods up to 4 weeks. The animals were then killed, and retinal and choroidal tissue was taken for investigation by both light and electron microscopy. Exposure to the lower intensity produced disruption of the visual cell outer segments and distension of the pigment epithelium. Recovery from this insult was rapid although disturbances in rod disc stacking and a loss of cone cell outer segments were evident 4 weeks after exposure. Exposure to the higher intensity resulted in necrosis of visual cells and pigment epithelial cells. Non-native phagocytic cells were active in the removal of cellular debris. Recovery from this insult was not observed. Four weeks after exposure much of the previously illuminated retina was reduced to disorganised Muller cells and occasional macrophages. PMID- 6906138 TI - Scanning electron microscopy of frozen-cracked, dry-cracked, and enzyme-digested retinal tissue of a monkey (Cercopithecus aethiops) and of man. AB - Cracking and enzyme-digestion methods were applied to retinal tissue from a monkey (cercopithecus aethiops) and from man. By scanning electron microscopy (SEM) of the various layers of the retina, as well as of single cells, cell connections and cell interiors were demonstrated in a three-dimensional form. The methods were particularly successful in demonstrating the fibre baskets of Muller cells and the tongue-like processes of the inner photoreceptor segments surrounding the outer segment. Cristae-like protrusions of the inner segments lying in rows along the axis of the segment, possibly disconnected interphotoreceptor contacts, were clearly seen. PMID- 6906136 TI - Vitreous membrane formation after experimental vitreous haemorrhage. AB - The formation of vitreous membranes after intravitreal haemorrhage was studied in rabbit eyes. Early detachment of the posterior vitreous was followed by the formation of large cellular membranes, composed of aggregated giant macrophages within fine collagen sheets. Progressive reabsorption of the cellular material resulted in acellular membranes composed of endogenous vitreous collagen. Fibroblastic activity was not observed, and it was considered that the vitreous body, particularly its hyaluronic acid component, may present a barrier to the invasion of fibroblasts and other cells during the resolution of vitreous clots. PMID- 6906137 TI - Cellular decay in the rat retina during normal post-natal development: a preliminary quantitative analysis of the basic endogenous rhythm. AB - The diurnal variation in the appearance of cell death in the rat retina during postnatal development was investigated. The frequency and the morphology of the necrotic cells and the mitotic figures were studied by light and electron microscopy at various stages of ontogenesis and at specified times during each day. Preliminary results show that there is a varying exponential behaviour of mean necrosis-densities at certain periods each day. This chronobiological pattern and the general problems of physiological cellular decay in the developing retina are discussed. PMID- 6906140 TI - Ultrastructural lesions of retinal pericapillary Muller cells in streptozotocin induced diabetic rats. AB - Seventeen Wistar inbred rats were made diabetic by a single injection of streptozotocin (50 mg/kg body weight) and were killed after periods of 3, 6, 9 or 12 months. Pathological changes in pericapillary Muller cells of the retina were studied using electron microscopy. Basement membrane-like material proliferated in the intercellular space of the Muller cell network and occasionally appeared to insinuate into the Muller cell cytoplasm far from capillary pericytes and endothelial cells. The part of the Muller cell that was enveloped by proliferating basement membrane-like material showed partial necrosis which was thought to contribute to the widening of the capillary wall. A breakdown of the retinal framework, which leads to capillary dilatation, was also thought to be associated with partial necrosis of Muller cells. Highly electron-dense bodies accumulated in the Muller cell cytoplasm which surrounded the retinal capillaries. Ultrastructurally, these dense bodies resembled lysosomes. Their increased number might reflect the altered metabolism of the diabetic retina. PMID- 6906141 TI - Endothelial cells in dominant cornea guttata. AB - A family with autosomal dominant cornea guttata in three generations is described. The investigated pedigree consisting of 25 healthy patients and 6 patients with cornea guttata. A few guttata were already present at an early age and very pronounced corneal endothelial guttata appeared in the middle-aged patients. No other ocular pathology was associated with this condition and the endothelial cell counts were not affected by guttata excrescences. The corneal thickness was normal in the affected and non-affected members of the family while bullous keratopathy did not seem to be associated with dominant cornea guttata in this family. PMID- 6906143 TI - Congenital retino-pigment epithelial malformation: a clinicopathological case report. AB - An unusual unilateral fundus lesion in a 16-year-old boy is described consisting of hyperpigmentation and presumed hypertrophy of the retinal pigment epithelium combined with malformation and thickening of the overlying sensory retina. Based on its clinical and histological characteristics, this lesion is considered to be a congenital retinal pigment epithelial malformation. PMID- 6906142 TI - Effects of timolol maleate on tear flow in human eyes. AB - Lacrimal function was studied in 30 patients treated for glaucoma, with 0.25% timolol eye drops. Rose bengal and fluorescein staining disclosed punctate epithelial defects in 11 eyes after one week. During the following weeks there defects disappeared spontaneously in most eyes. Schirmer tests (I and II), tear lysozyme and pre-corneal film break-up time were significantly decreased by the treatment, while tear immunoglobulins were unimpaired. The authors conclude that topical timolol treatment decreases tear production. This effect is quantitatively limited and does not appear dangerous for normal eyes, although it may become so for eyes with an originally low lacrimal secretion. PMID- 6906144 TI - Myopia and glaucoma. AB - 2,528 visual fields of patients with glaucoma were examined. All atypical nerve fibre bundle defects (NFBD) were selected and all myopes. Myopic defects are a) enlargement of the blind spot, occurring in 18% to 30% of the myopic eyes depending in the degree of myopia, b) super-temporal refraction defect (2-6%) and c) irregular defects due to myopic choroidal dystrophy. Atypical NFBD were found in only a few non-myopes but in a large number of myopes. Temporal NFBD occurred in 16% and cecocentral NFBD in 9 to 18% of myopic glaucoma (MG). It is difficult to predict the existence of an atypical defect from optic disc evaluation. PMID- 6906145 TI - [Effect of serum osmolarity, arterial blood pressure and volume loss on IOP during hemodialysis, hemofiltration and simultaneous hemofiltration/hemodialysis (author's transl)]. AB - In 29 patients suffering from chronic renal failure intraocular pressure was measured during different therapeutic regimens. Conventional hemodialysis (principle of transport diffusion, n = 15) led to an increase in IOP after one hours treatment. In individuals complaining of headaches during dialysis a marked increase in IOP was observed indicating a disequilibrium syndrome. Hemofiltration is characterized by mass transfer and exchange of plasma water. When this treatment was applied to 6 patients IOP was elevated during the second hour. Simultaneous hemofiltration/hemodialysis (n = 8) had no influence on IOP behaviour. Statistically there was no correlation between the behaviour of serum osmolarity, arterial blood pressure, loss of body weight and IOP. PMID- 6906146 TI - [Light- and electron microscopic findings of an adenocarcinoma of the caruncle (author's transl)]. AB - The clinical, histological and electron microscopical findings of an adenocarcinoma of the caruncle are discussed. This type of adenocarcinoma differs neither in clinical development nor fine tissue structure from the adenocarcinoma of the Meibomian or Zeis's glands. Although, it seems to have a better prognosis than columnar cell carcinoma, radical excision and postoperative radiotherapy are recommended. The possibility of confusion with chronic inflammatory processes (chalazion) is pointed out. PMID- 6906147 TI - [Televised flurescein angiography of the retina--new technical aspects (author's transl)]. AB - A television-fundus-camera is described, which makes possible video-tape recordings of both conventional fundal- appearances as well as fluorescein angiograms. Minimal illumination of the fundus with a spectral lamp is utilized. The use of a spectral lamp optimizes the excitation of fluorescein dye and the intensity of the illumination can therefore be reduced to a minimal level. Thus, patient inconvenience is minimized and ocular immobility can be maintained for the duration of the examination, which results in better quality recordings. PMID- 6906148 TI - Ultrastructures of the normal surface of corneal epithelium of the heterozygous rhino mouse with special reference to so-called epithelial holes. AB - The surface structures of the corneal epithelium of the heterozygous rhino mouse were examined by transmission electron microscopy and scanning electron microscopy. The surface structures of the corneal epithelium were composed of microvilli, microplicae and epithelial holes. Microvilli and microplicae showed the same features as those described previously. However, some microvilli bent at the top of stalk and looked like microplicae by scanning electron microscopy. The structure of epithelial holes was different from that reported previously. Epithelial holes with elevated rim demonstrated by scanning electron microscopy were formed by a large fold or process of epithelial cells in the outermost layer. Microvilli were present on the process (margin) and floor of epithelial holes. Thus microvilli on the floor belong to the outermost layer, not to the second layer. PMID- 6906149 TI - [Decreasing local stereopsis with increasing horizontal disparity, indicating decreasing density of binocular cortical projection towards the limits of Panum's area (author's transl)]. AB - Measuring local stereopsis by means of random dot stereograms with increasing horizontal disparity, the relative density of binocular cortical projection has been determined at a distance of 75 min of arc from the fovea. The accuracy of stereoscopic perception decreased with increasing horizontal disparity. The reciprocal value of the error frequency was used to measure the density of binocular cortical projection. Panum's area at the above mentioned distance from the fovea can be constructed by plotting the error frequency against the horizontal disparity. We observed a decrease of the relative density of binocular cortical projection towards the limits of Panum's area without a sharp break. The results are in agreement with those reported by Bishop and Henry and Joshua in the cat (receptive field disparity). The theory of stereopsis as proposed by Bishop explains our findings well and may be transferred to binocular vision in man. PMID- 6906151 TI - Familial exudative vitreoretinopathy. AB - A pedigree of familial exudative vitreoretinopathy is presented; 12 out of 37 family members examined were affected and the inheritance pattern was compatible with an autosomal dominant disease. Clinical findings and fluorescein angiographic studies of patients with the early stages of the disease support the concept that familial exudative vitreoretinopathy is a disease primarily of the small peripheral vessels leading to peripheral fibro-vascular mass lesions. PMID- 6906150 TI - [Does dionine (aethylmorphin) influence the lymph drainage of the eye? (author's transl)]. AB - Drainage of a lymphotropic solution of Tc-99m sulfur colloid from the vitreous body was studied in twelve rabbits. Shortly after the application of this tracer, six of these rabbits had an injection of 0.06 ml, 0.5% dionine (Aethylmorphin) solution into the retrobulbar space. After the dionine injection, the decay of radio-activity from the eyes was significantly increased. The radio-activity in the control group approximated to 81.6% of the total applied radio-activity after six hours, whereas the radio-activity in the eyes of the dionine treated group was, on average, only 5% after the same time interval. Simultaneously, the radio activity in the cervical lymph nodes increased significantly from approximately 0.10% in the control group to 0.67% in the dionine treated group. It is not known, as yet, whether dionine increases lymph drainage in man. PMID- 6906152 TI - Courses of diabetic retinopathy. AB - A follow-up study on 93 patients suffering from diabetic preretinopathy showed different courses of development. Predominantly occlusive types of microangiopathy were significantly more predisposed to a rapid progression of lesions than predominantly exudative types or occlusive exudative types. In addition, transition of one type into the other and reversibility of all symptoms were observed. PMID- 6906153 TI - Cytological studies on the developing vitreous as related to the hyaloid vessel system. AB - The embryonic development of the cell population of the mammalian vitreous has been traced to two sources: the undifferentiated mesenchymal cells of the eye primordium and the primitive reticular cells of the bone marrow. Undifferentiated mesenchymal cells invade the future vitreous space in two ways: through the annular opening between the rim of the optic cup and the lens primordium, and through the open embryonic fissure. They differentiate into prevascular cells, hemangioblasts, and fibrocytes located in the area of the optic nerve head. From the very beginning of fetal development, another ameboid-type cell of mesenchymal origin makes its entrance into the vitreous through the hyaloid vessels; these monocyte-like cells differentiate into hyalocytes and populate a well-defined area of the cortical vitreous close to the retina and to the ora serrata. Gamma irradiation (600 rads) of newly born rabbits and cats decreases the number of migrating amebocytes in their vitreous; 24 h later, however, they are replaced by monocytes from the hyaloid vessels. PMID- 6906155 TI - Automatic (Octopus) and manual (Goldmann) perimetry in glaucoma. AB - Of 115 patients with chronic open angle glaucoma or suspected glaucoma 115 eyes were subjected to a visual field examination with the manual Goldmann perimeter and the automatic Octopus perimeter. In 84.4 +/- 8.9% the automaton detected more visual field loss, including 27.8 +/- 10.9% of the eyes where no visual field loss was found by the manual perimetry. Since some eyes with normal fields on manual perimetry and abnormal fields detected by automatic perimetry remained abnormal on retesting, it is assumed that scotomas found by automatic perimetry and not shown by manual perimetry constitute false-negative manual fields rather than false-positive automatic fields. PMID- 6906154 TI - Presence of lysosomal hyaluronidase in human corneoscleral tissue. AB - Hyaluronidase activity in human corneoscleral tissues was biochemically studied. The corneoscleral junction, particularly the inner layer, showed higher activity than other corneoscleral tissues. The possible role of lysosomal hyaluronidase in the trabecular meshwork is discussed. PMID- 6906156 TI - [Research on the biomechanical vibration behaviour of man's bulbi (author's transl)]. AB - Mechanical vibration may lead to a decrease in visual performance. This may be expected if the natural frequency of the eye is excited. Experiments wit eight subjects and one repeat were carried out with the aim of calculating the biomechanical transmission of vibration between the cranium and the eye. The oscillation of the reflex-point of the cornea and of a light-point on the forehead were observed by a TV-camera and recorded using a multipoint-X-Y-tracker system with a direct writer. The analysis showed typical resonance curves for the eye with maxima at 25-31.5 Hz typical to those found in animal experiments using other methods. Therefore at places of work transmission of such vibration frequencies to the head should be avoided to prevent a decrease in visual performance. PMID- 6906157 TI - [Early effects of clonidine, epinephrine, and pilocarpine on the intraocular pressure and the episcleral venous pressure in normal volunteers (author's transl)]. AB - In four different groups of eight normal volunteers the intraocular (IOP) and episcleral venous pressures (EVP) were measured before, and at 7.5, 15, 30, 45, and 60 min after topical application of one drop of clonidine (1/4%), epinephrine (1%), or pilocarpine (2%) by means of applanation tonometry or the air-jet method, respectively. The results were compared with a control group. In the control group the IOP decreased by 16% until the fourth measurement. Subsequently it increased to -10% after 60 min. The EVP remained unchanged. After clonidine application the IOP decreased throughout the whole experiment (-31% after 1 h) and after the third measurement the IOP decrease was significantly more marked than in the control group. The EVP I diminished significantly during the first 15 min by 25% and then increased, reaching its initial value after 60 min. IOP and EVP I showed parallel behavior only during the first 30 min. Topical application of epinephrine was followed by a much smaller decrease in IOP (17% after 60 min); compared to the control group the differences were minor. The EVP I was reduced significantly by 15% below the initial level after 45 min while EVP and IOP behaved identically. After pilocarpine application the IOP rose initially (7% after 7.5 min) and decreased markedly after 10 min (33% after 1 h). Compared to the untreated volunteers there were significant differences at nearly all times. At the outset the EVP I increased significantly (29% after 7.5 min), and then decreased again until it regained the initial value after 30 min. Only at the beginning of the experiment were the reactions of IOP and EVP similar. PMID- 6906158 TI - Comparative investigations of catalase activity in different ocular tissues of cattle and man. AB - As previously published, ocular catalase activity was measured by Warburg's respirometer, the examined material being taken from the local slaughterhouse and keratoplasty-donor eyes. The results were given in microliter O2 per mg soluble protein (Biuret's solution) and showed an extensive parallelism between human and bovine eyes: They were in a decreasing order of catalase activity, i.e., conjunctiva > retina > vitreous > sclera > iris > choroid > cornea > aqueous humor > serum > lens. In the latter, catalase activity was a sensitive indicator of aerobic metabolism. Oxidative processes in the vitreous merit more consideration. PMID- 6906159 TI - [Acute arterial hypotension by sodium-nitroprusside and intraocular tension (author's transl)]. AB - The relationship between intraocular pressure by short-term intravenous Sodium Nitroprusside induced arterial hypotension in intubation-anaesthesia was studied in 19 cats. A reduction of the blood pressure from an average of 168 mm Hg to 89 mm Hg (that is 47%) was followed by a clearly reproducible reduction of intraocular pressure from an average of 22 mm Hg to 10 mm Hg (that is 55%). These findings for the "closed" eye are a prerequisite for the understanding of the effects of sodium-nitroprusside in the "open" eye. PMID- 6906161 TI - Ocular hypertension in primary glaucoma: a new hypothesis. AB - Some considerations of the vascular events occurring the uvea during the course of glaucoma are reported and a mathematical model is adopted to clarify the interdependence between intraocular pressure, rate of blood flow, blood pressure gradient, and the number of unobstructed capillary vessels in the uveal membrane. By means of this mathematical model the physiopathological vascular cause of the rise in intraocular pressure is confirmed (also independently of an obstacle to aqueous outflow), and the clinical implications in relation to visual sensory impairment are emphasized. PMID- 6906160 TI - [The effect of timolol and dipivalyl-epinephrine in the treatment of the elevated intraocular pressure (author's transl)]. AB - Twenty-seven patients with ocular hypertension or open angle glaucoma were tested to see if, and to what extent, timolol and dipivalyl-epinephrine produced a supplementary reduction of intraocular pressure. In a shortterm study, 14 patients were tested with timolol (0.1%) and dipivalyl-epinephrine (0.25%). Simultaneous application of both substances produced a statistically more significant reduction of intraocular pressure than either timolol (0.1%) or dipivalyl-epinephrine (0.25%) alone. In 13 patients a comparison was made between patients who received both timolol (0.25%) and dipivalyl-epinephrine (0.1%) bis x and patients who received only timolol (0.25%) bis x over a period of 6, 9 and 12 weeks. Both substances used in combination produced a statistically more significant reduction in intraocular pressure than timolol (0.25%) bis x alone. The simultaneous application of an alpha and beta-adrenergic agonist and beta adrenergic antagonist is not contradictory. The results are discussed on the basis of the mode of action of the applied substances. PMID- 6906162 TI - Visual field decay in normal subjects and in cases of chronic glaucoma. AB - Visual field information obtained with the automatic Computer-Perimeter ('Competer') can be condensed into a single numerical value. This performance measure was applied to a normal population to determine the physiologic decay of retinal sensitivity with aging. Further, the development of this performance measure was followed in 54 glaucoma eyes which were divided into three groups: Untreated, treated with satisfactory intraocular pressure (IOP) regulation, and treated with satisfactory IOP regulation. All eyes were examined perimetrically on at least three separate occasions. Decaying performance measures were found in the preponderance of glaucoma eyes. Therapy aimed at lowering the IOP did not offer a protective effect. Papillary hemorrhage and a significant decay in performance are usually found in the same eye. PMID- 6906164 TI - Anterior pars plana vitrectomy in ciliary and iris block glaucoma. AB - Ciliary and iris block glaucoma in aphakic and phakic eyes is characterized by the accumulation of aqueous humor in the vitreous cavity causing an increase in vitreous volume, a flattening of the anterior chamber, and an elevation of intraocular pressure. As vitreous blocks the space between the ciliary body and the iris or lens, respectively, an anterior vitrectomy via the pars plana is the logical surgical approach. This operation was performed in one phakic and 15 aphakic eyes with so-called pupillary block. The anterior chamber retained a normal depth in each case. Post-operatively the vitreous was found to be completely removed from the posterior chamber and the epiciliary space, rendering a free communication between the ciliary body and the posterior and anterior chamber. Early surgery in aphakic eyes with a flat anterior chamber resulted in a prompt normalization of intraocular pressure, whereas eyes with a block duration of over 4 weeks were at high risk of developing a secondary outflow resistance probably due to chronic angle closure. PMID- 6906163 TI - Ultraviolet induced lysosome activity in corneal epithelium. AB - A 5,000 W Xe-Hg high pressure lamp and a double monochromator were used to produce a 3.3 nm half-bandpass ultraviolet radiation at 295 nm. Pigmented rabbit eyes were irradiated with radiant exposures from 140 Jm-2 to 10,000 Jm-2 and evaluated by slit-lamp biomicroscopy, light and electron microscopy. Corneal threshold (Hc) was 200 Jm-2 and lens threshold (HL) was 7,500 Jm-2. The most repeatable and reliable corneal response to these levels of UV was the development of corneal epithelial granules. Histological changes included a loss of superficial epithelial cells and selective UV induced autolysis of the wing cells. It is suggested that the biomicroscopically observed granules are the clinical manifestation of the secondary lysosomes revealed by light and electron microscopy. It is proposed that UV breaks down the primary lysosome membranes to release hydrolytic enzymes which in turn form the secondary lysosomes during autolysis. Extreme levels of radiant exposure at 295 nm result in indiscriminate destruction of all layers of the corneal epithelium, but the posterior cornea was spared. PMID- 6906165 TI - Cyclocryokoagulation. Sequelae of induced alterations and effect of a prostaglandin-inhibitor on the breakdown of the blood-aqueous barrier. AB - Histopathological changes following cyclocryokoagulation in a group of rabbits pretreated with acetylsalicyclic acid (ASA) were studied and compared with similar changes in a control group. As observed clinically, macroscopical and histological differences were only noted in the early phase after the procedure. In this phase, all operated eyes revealed an immense vascular response with edema, exudation and extravasation of blood cells. The treated animals, however, showed some reduction of tissue edema than the animals not treated. At a later stage there is an necrosis of the stroma with reduction of small vessels and tissue cells. The reparative process, tending to restore both epithelial and stromal lesions, begins already in the 3rd. week after cyclocryokoagulation. Neither the epithelial nor the stromal alterations differed significantly in any of the operated eyes at this stage. This indicates that ASA mainly affects an obviously prostaglandin-mediated acute vascular response. The disruption of the epithelial barrier may be aggravated by the subsequent stromal alterations, but does not seem to be influenced by ASA. PMID- 6906166 TI - [A model to measure the volume of choroidal melanomas (author's transl)]. AB - A formula to calculate the volume of biconvex-shaped malignant melanomata of the choroid is presented. The axial length of the eye, whatever the refractive error, has nearly no influence on the results. A computer printout of the range of results is added for clinical use. The reliability of contact B-Scan ultrasonography to obtain those parameters is examined using various tumor models of defined sizes. PMID- 6906168 TI - The fellow eye in retinal detachment. AB - The examination findings of the fellow eye of 534 patients affected by a unilateral retinal detachment are reported. Nearly 90% of these eyes showed degenerative areas and about 20% showed one or more retinal breaks. These findings are quite different from those reported in examinations of 'random eyes' and suggest that fellow eyes are 'high risks' that often need prompt prophylactic treatment. PMID- 6906167 TI - [Focal epiretinal fibroplasias overlying photocoagulations in diabetic retinopathy (author's transl)]. AB - This clinico-pathological study compares photocoagulated diabetic retinae with cases of spontaneous epiretinal fibroplasia. Focal epiretinal fibroplasias were found overlying 5-10% of the Xenon-arc photocoagulations but not over Ruby-laser coagulations. These foci are contiguous-forming membranes but they do not cause surface wrinkling. The topography and appearance of the fibrous components of these membranes in trypsin-digest specimens are described and compared with foci of spontaneous epiretinal surface wrinkling. Destruction of the inner retinal surface by heavy coagulation is believed to be the principal cause of focal post photocoagulation fibroplasia. Other possible pathogenetic factors are discussed. PMID- 6906170 TI - Macular holes. AB - Twenty-four eyes with macular holes have been followed for periods ranging from one to four years. Each hole was demonstrated, clinically, to be full thickness and associated with a small, localized, retinal detachment and a posterior vitreous separation. With one exception, all eyes were within three diopters of emmetropia, and only one eye developed progression of the retinal detachment. A high incidence of systemic estrogen therapy was noted in these patients. PMID- 6906171 TI - Changing appearance of retinal arteriovenous malformation. AB - Retinal arteriovenous malformations (racemose angiomas) are usually described as non-changing congenital vascular anomalies. The authors describe prominent retinal vascular changes that occurred in the fundus of a patient with a complex retinal arteriovenous malformation as part of the Wyburn-Mason syndrome during a follow-up period of 17 years. PMID- 6906172 TI - An introduction to nursing theories, concepts, and models. PMID- 6906169 TI - Specialized intramembrane organizations of the cone presynaptic membrane in the pigeon retina. Freeze-fracture study. AB - The presynaptic membranes of the cone cell endings of the pigeon retina were investigated using the freeze-fracture technique. En face views of the cytoplasmic leaflet (P-face) of the split presynaptic membrane revealed several specialized membrane organizations, 1. membrane particle aggregates composed of 10-20 particles which were larger than the usual ones seen in the cell membrane, 2. fenestration-like circular structures of 30-50 nm in diameter which were not surrounded by membrane particles. 3. similiar circular structures as described above but which were accompanied by a few membrane particles on the circular margin and were considered to be an intermediate form of the first and second membrane structures. These three structures appeared simultaneously in one fracture plane of the presynaptic membrane; were situated at the same intervals from one another and were approximately equal in size to synaptic vesicles (30-50 nm). These findings strongly suggested that these three structures were serial events in presynaptic membrane organization. When fortuitous cross fractures exposed both the P-face of the presynaptic membrane and the adjacent cytoplasm of the cone ending, fusion of the synaptic vesicles to the presynaptic membrane was observed, and was considered to be the opening of the synaptic vesicle to the synaptic cleft. These openings were also situated at the same distance as the structures described above. These findings demonstrate the process of exocytosis of the synaptic vesicles by which the chemical transmitter is probably released to the synaptic cleft. PMID- 6906173 TI - Implantable devices should be sterilized ahead of time. PMID- 6906175 TI - Can employer block nurse from acting as expert witness? PMID- 6906174 TI - Debt-ridden Denver health system to stretch staff with technicians. PMID- 6906176 TI - If we teach holistic care, can we exclude perioperative nursing? PMID- 6906177 TI - OR experience teaches continuity of care. PMID- 6906179 TI - Chapter promotes student OR experience. PMID- 6906178 TI - Linking the OR to curriculum goals. PMID- 6906180 TI - The hypothesis: an educated guess. PMID- 6906181 TI - American College of Surgeons: qualifications of the first assistant in the operating room. PMID- 6906183 TI - Proposed recommended practices for traffic patterns in the surgical suite. PMID- 6906184 TI - A practical guide for perioperative practice. PMID- 6906182 TI - Charting a course for the first assistant. PMID- 6906185 TI - Perioperative nursing can be cost effective. PMID- 6906186 TI - Alcohol foam for hand disinfection. PMID- 6906187 TI - Getting a degree requires balancing multiple roles. PMID- 6906188 TI - Avoid legal problems by knowing your scope of practice. PMID- 6906191 TI - Cardiac arrest in the OR. PMID- 6906189 TI - Is hepatitis carrier liable for infection of surgical patient? PMID- 6906190 TI - A surgical answer to spastic dysphonia. PMID- 6906192 TI - The research approach. PMID- 6906193 TI - Active site mapping of human and rat urinary kallikreins by peptidyl chloromethyl ketones. PMID- 6906194 TI - Inhibition of progesterone receptor activation by vanadate. PMID- 6906195 TI - How different are college-trained nurses? PMID- 6906196 TI - N.S.W. College of Nursing President speaks out on tertiary education. PMID- 6906197 TI - Key educationist's view on the need for nursing education. PMID- 6906198 TI - Two days in the life of a rural health sister. PMID- 6906199 TI - Sunday at the park. PMID- 6906200 TI - Acute pancreatitis--the pathophysiology of multi-systems failure. PMID- 6906202 TI - The nursing interview. PMID- 6906201 TI - Personal space theories: lessons for nurses. PMID- 6906203 TI - Management of terminally ill cancer patients and facilities and services for their care. PMID- 6906204 TI - Evaluation of student clinical performance. PMID- 6906205 TI - Preparing nurses for an expanded role in primary health care delivery. PMID- 6906207 TI - The process of communication. PMID- 6906206 TI - The mothercraft nurse in a child psychiatric unit. PMID- 6906208 TI - Natural birth control. PMID- 6906209 TI - Royal Australian Nursing Federation 19th National Students of Nursing Conference 13-17th October, 1980. "The role of accountability in nursing of the future". PMID- 6906211 TI - How American nurses see their professional goals. PMID- 6906210 TI - Number twenty-seven. PMID- 6906212 TI - Laxatives. PMID- 6906213 TI - International Year of Disabled Persons. Case history of Richard. PMID- 6906214 TI - International Year of Disabled Persons. Spasticity: the nursing management. PMID- 6906215 TI - National Steering Committee: opposition to the proposed contractual arrangements between hospital schools of nursing and colleges of advanced education and accreditation of hospital course. PMID- 6906217 TI - Designing a nursing care plan. PMID- 6906216 TI - A child, adolescent and family health service (Paper 6). PMID- 6906218 TI - Communicate. PMID- 6906219 TI - Treatment of burnt ears. PMID- 6906220 TI - Prevention: what is happening in South Australia. PMID- 6906224 TI - Collaborating in care: Paper 2. PMID- 6906223 TI - Collaboration in care: Paper 1. PMID- 6906221 TI - Parents & Children Anonymous. PMID- 6906222 TI - Coping with congenital blindness. PMID- 6906225 TI - Collaboration in care - Paper 3. PMID- 6906227 TI - How we saw the need for a diabetic clinic - Paper 5. PMID- 6906226 TI - Collaboration in care (Paper 4) - a doctor's viewpoint. PMID- 6906228 TI - The human complement system: assembly of the classical pathway C3 convertase. AB - The assembly of the classical pathway C3 convertase in the fluid phase has been studied. The enzyme is assembled from C2 and C4 on cleavage of these proteins by C1s. Once assembled, the enzyme activity decays rapidly. Kinetic evidence has been obtained that this decay is even more rapid than previously suggested (kdecay is 2.0 min-1 at 37 degrees C). As a result, optimal C3 convertase activity is only observed with high C1s levels, which result in rapid rates of cleavage of C2 and increased rates of formation of the C3 convertase. Using high concentrations of C1s at lower temperatures (22 degrees C) in the presence of excess substrate we have demonstrated kinetically that the enzyme comprises an equimolar complex of C4b and cleaved C2. We have obtained direct evidence from gel-filtration experiments for the role of C2a as the catalytic subunit of the enzyme. C2b appears to mediate the interaction between C4 (or C4b) and C2 at pH 8.5 and at low ionic strength where the interactions can easily be detected. It may therefore be important in the assembly of the enzyme, though it is not involved in the catalytic activity. The decay of the C3 convertase reflects the release of C2a from the C4b x (C2b) x C2a complex, and the stabilizing effect of iodine on the C3 convertase is therefore apparently one of stabilizing the C4b C2z interaction, which is otherwise weak. C1s is not a part of the C3 convertase enzyme. PMID- 6906230 TI - Inhibition of rifampin of elastase and lysozyme secretion in mouse peritoneal macrophages. PMID- 6906231 TI - The rights of the terminally ill. PMID- 6906229 TI - The binding of human complement component C4 to antibody-antigen aggregates. AB - The binding of human complement component C4 to antibody-antigen aggregates and the nature of the interaction have been investigated. When antibody-antigen aggregates with optimal C1 bound are incubated with C4, the C4 is rapidly cleaved to C4b, but only a small fraction (1-2%) is bound to the aggregates, the rest remaining in the fluid phase as inactive C4b. It has been found that C4b and th antibody form a very stable complex, due probably to the formation of a covalent bond. On reduction of the C4b-immunoglobulin G (IgG) complex, the beta and gamma chains, but not the alpha' chain, of C4b are released together with all the light chain, but only about half of the heavy chain of IgG. The reduced aggregates contain two main higher-molecular-weight complexes, one shown by the use of radioactive components to contain both IgG and C4b and probably therefore the alpha' chain of C4b and the heavy chain of IgG, and the other only C4b and probably an alpha' chain dimer. The aggregates with bound C1 and C4b show maximal C3 convertase activity, in the presence of excess C2, when the alpha'-H chain component is in relatively highest amounts. When C4 is incubated with C1s in the absence of aggregates, up to 15% of a C4b dimer is formed, which on reduction gives an alpha' chain complex, probably a dimer. The apparent covalent interaction between C4b and IgG and between C4b and other C4b molecules cannot be inhibited by iodoacetamide and hence cannot be catalysed by transglutaminase (factor XIII). The reaction is, however, inhibited by cadaverine and putrescine and 14C-labelled putrescine is incorporated into C4, again by a strong, probably covalent, bond. It is suggested that a reactive group, possibly an acyl group, is generated when C4 is activated by C1 and that this reactive group can react with IgG, with another C4 molecule, or with water. PMID- 6906232 TI - Cultural variations among clients' diets. PMID- 6906233 TI - Problems of the unwed father. PMID- 6906234 TI - The 'knotting' problem in proteins. Loop penetration. AB - The 'knotting' problem in proteins is redefined in terms of the more general concept of loop penetration. Disulfide-containing proteins are represented as linear graphs, and it is proposed that proteins with nonplanar graph representations display loop penetrations in their three-dimensional structure. With this argument, it is shown that the occurrence of loop penetration in disulfide-containing proteins is approximately that expected based on the random pairing of sulfhydryl groups. It is argued that loop penetration is not as rare as currently held. PMID- 6906236 TI - A look at career mobility. Part 2. PMID- 6906237 TI - Intestinal helminths. PMID- 6906238 TI - Overworked and undernourished? PMID- 6906235 TI - Effect of surfaces on fluid-phase prekallikrein activation. AB - The activation of prekallikrein by factor XII fragments (XIIf), during incubation in plastic tubes was previously noted to be increased by high molecular weight (HMW) kininogen as well as other plasma proteins. In this report, we investigated the mechanism responsible for this increase. Although we confirmed that HMW kininogen, bovine serum albumin, fibrinogen, cold insoluble globulin, and mixed phospholipids apparently increased prekallikrein activation, we found that the product of prekallikrein activation (kallikrein) lost substantial activity in less than 0.5 min after exposure to a variety of fresh surfaces. This loss was partially prevented by the presence of various proteins and phospholipids. Similar protection against inactivation of XIIf, the enzyme in this reaction, was also found. In contrast, no loss of the substrate, prekallikrein, was observed during incubation. The loss of kallikrein activity was found to be proportional to the surface area of the incubation vessel as well as the concentration of kallikrein. Further loss of kallikrein activity could also be prevented by pretreating the vessel with kallikrein. We therefore conclude that various substances apparently affect prekallikrein activation in a purified system by preventing the enzyme and product in the reaction mixture from losing activity due to adsorption to a surface. PMID- 6906239 TI - Homosexuality: the cost of being different. PMID- 6906240 TI - The quiet revolution: establishing a nurse-midwifery practice. PMID- 6906241 TI - The nurse consultant: an independent practice setting. PMID- 6906242 TI - Appearance, behavior and capabilities. Teaching new parents infant ABC's. PMID- 6906243 TI - The hidden epidemic. PMID- 6906244 TI - The Nestle controversy. PMID- 6906248 TI - [Self-evaluation of the nursing process]. PMID- 6906246 TI - You and the law. When nurses fail to communicate. PMID- 6906245 TI - Generalist to specialist: an inservice challenge. PMID- 6906247 TI - [Effect of ionizing radiation on enzymes. III. The effect of gamma irradiation on the activity of trypsin in pancreatin]. PMID- 6906250 TI - [Teaching methodology in the training of nursing technics]. PMID- 6906249 TI - [On understanding of the object of nursing in comprehensive nursing study]. PMID- 6906252 TI - [Nursing and nursing education. 6. Continuing education]. PMID- 6906251 TI - [Constant gracefulness and kindness expected in nursing instructors]. PMID- 6906253 TI - [An equal nurse-patient relationship and understanding of the patient - in a study of a patient with alcoholism]. PMID- 6906254 TI - "Social" baths. PMID- 6906255 TI - Action plan. PMID- 6906257 TI - Attitudes to incontinence. PMID- 6906256 TI - Attitudes to incontinence. PMID- 6906258 TI - Care study - two different people. (1). Where will it end? Attitudes to incontinence. PMID- 6906259 TI - Care study -- two diifferent people. 2. A long, hard haul. Attitudes to incontinence. PMID- 6906263 TI - Toxicological implications of polymorphic drug metabolism. AB - The occurrence of genetic polymorphisms of drug metabolism means that populations contain subgroups (phenotypes) that differ sharply in their abilities to effect a number of metabolic reactions. Because of this, major interphenotype differences occur in responsiveness to drugs and toxic substances. The well established genetic polymorphisms of acetylation and hydrolysis illustrate the important association that exists between phenotype and propensity to develop toxic and exaggerated responses to some substances. Recently, for metabolic oxidation, a new genetic polymorphism of drug metabolism has been described and it promises to provide a better understanding of inter-individual variability in the metabolic handling of, and responsiveness to, drugs and toxic substances. The following effects of the polymorphism are described here: (a) its influence in determining variable presystemic metabolism and hence systemic drug availability; (b) its role in determining alternative toxic pathways of metabolism in individuals who have a genetically determined impairment of oxidative capacity and (c) its influence on the development of agranulocytosis associated with metiamide administration. PMID- 6906260 TI - Induction of drug-metabolizing enzymes by phenobarbitone: structural and biochemical aspects. AB - Two aspects of the induction of microsomal monooxygenases by phenobarbitone have been investigated. First, structural associations between mitochondria and single cisternae of rough endoplasmic reticulum (mitochondria--RER complexes) may operate as functional units in the biosynthesis of cytochrome P-450. This was deduced from (i) studies on the subcellular distribution of the phenobarbitone induced incorporation of leucine into microsomal proteins including apocytochromes P-450 and (ii) the incorporation of labelled delta-aminolaevulinic acid into the haem prosthetic group of cytochrome P-450. Secondly, in hepatocytes from chick embryo in primary monolayer culture, induction of cytochrome P-450 haemoproteins was markedly influenced by changes in the proliferative activity of hepatocytes. Inducibility of cytochrome P-450 by phenobarbitone and by beta naphthoflavone was decreased in cultures with 'spontaneous' or experimentally increased proliferative activity of hepatocytes. Treatment with inhibitors of DNA synthesis increased the induction response. PMID- 6906262 TI - Regulation of human drug metabolism by dietary factors. AB - Several dietary factors influence the oxidative metabolism of chemicals in humans. Increasing the ratio of protein to carbohydrate or fat in the diet, feeding cabbage and brussels sprouts or feeding charcoal-broiled beef for several days stimulates human drug metabolism. The chronic ingestion of ethanol stimulates drug metabolism whereas the chronic ingestion of methylxanthine containing foods inhibits drug metabolism. In contrast, an increase in the ratio of fat to carbohydrate in the diet of normal subjects or the fasting of obese individuals for several days has little or no effect on drug metabolism. Flavonoids in edible plants influence the metabolism of foreign chemicals by human liver in vitro. The addition of flavone, tangeretin or nobiletin to human liver microsomes activates both the hydroxylation of benzo[alpha]pyrene and the metabolism of aflatoxin B1 to mutagens. On the other hand, quercetin, kaempferol, morin and chrysin, which are also normally occurring flavonoids, inhibit the hydroxylation of benzo[alpha]pyrene by human liver microsomes. PMID- 6906261 TI - Substrate-dependent irreversible inactivation of cytochrome P-450: conversion of its haem moiety into modified porphyrins. AB - 2-Allyl-2-isopropylacetamide and other drugs containing either an allyl, a vinyl or an ethynyl unsaturated side chain are metabolized by liver cytochrome P-450 to reactive derivatives that irreversibly inhibit the haemoprotein by a suicidal type of inactivation. The main target is the haem moiety of cytochrome P-450 which is converted into abnormal porphyrins. These have been isolated from the liver of treated rats, extensively purified and compared with model porphyrins. The abnormal porphyrins incorporate metal ions in vitro much more readily than does their parent porphyrin, protoporphyrin. They are also much more basic than protoporphyrin, and on titration with a strong acid they readily give rise to a porphyrin monocation which then requires relatively large amounts of acid for conversion to the porphyrin dication. In all these respects and also in the intensity of their bathochromic shifts these abnormal porphyrins closely resemble N-alkylated porphyrins and they markedly differ from porphyrins that are substituted at one of their meso-carbon positions or which bear electron withdrawing substituents at the beta-positions of the pyrrole rings. This suggests strongly that reactive derivatives of the unsaturated drugs act as electrophilic reagents and alkylate one of the pyrrole nitrogen atoms of cytochrome P-450. A model centred on the apoprotein of cytochrome P-450 is considered for the degradation of liver haem caused by unsaturated drugs. The apocytochrome may accept exchangeable pools of liver haem for degradation, leading to a state of haem depletion and to activation of delta-aminolaevulinate synthase. PMID- 6906265 TI - The influence of nutrition and inducers on mechanisms of toxicity in humans and animals. AB - A high proportion of toxic and carcinogenic effects of chemicals develop through the pathway of lethal synthesis. A part of this pathway is along the inducible cytochrome P-450-linked enzyme system. It has previously been suggested that the variations in disease patterns between individuals and between national groups may be due to differences in nutritional intake which in turn act by altering the pathways controlled by cytochrome P-450. However, patients with epilepsy, who are taking large amounts of inducing anticonvulsants, and who are known to have increased cytochrome P-450-linked enzyme activity, fail to show clear-cut changes in their patterns of mortality. It is possible that the reactions in the cytochrome P-450 pathways are not usually rate-limiting steps in toxicity in humans, and that we must look elsewhere, beyond the activation step, for the cause of variability in human responses to toxic materials in the environment. There are in current circulation three major theories of acute cell injury by chemicals. Using isolated liver cells and slices we conclude that none of them offers a reasonable explanation of the events of cell injury and necrosis in their usual simple form. Lipid peroxidation and calcium entry into cells can be blocked by antioxidants and calcium-free media, without interference with cell injury. Covalent binding of p-aminophenol to liver is far greater than binding of paracetamol, but it does not cause cell injury. The reversibility of some cell injuries implicates the existence of specific metabolic blocks by reactive metabolites rather than any generalized attack by insertion of metabolite groups. PMID- 6906264 TI - Toxicological significance of liver hypertrophy produced by inducers of drug metabolizing enzymes. AB - Changes in enzyme activity due to induction by chemicals is an important property that can determine the type of response seen in tissues exposed to environmental chemicals. Two major types of response, acute irreversible liver cell injury or death (necrosis) and long-term cancer induction, are discussed in terms of their modulation by enzyme induction. Most commonly, enzyme induction leads to a more severe toxic response by the liver, and to more cell death. However, inducers may have a protective effect, especially in carcinogenesis, when they most frequently protect against cancer induction if used early in the process. There is a discrepancy between this observation and the increase in mutagenic activity of liver preparations observed after induction. However, when enzyme induction occurs at a later stage, after initiation, it often accelerates or promotes cancer induction. Also, new cell populations constantly observed during liver carcinogenesis are composed of very hypertrophic hepatocytes containing a large amount of smooth endoplasmic reticulum. This is associated with a radical change in enzyme activities in the reticulum, which may account in part for the characteristic resistance exhibited by initiated cells to hepatotoxins and carcinogens. The resistance is considered to be an important property that may play a key role in the development of cancer under some circumstances. PMID- 6906266 TI - Influence of environmental chemicals on drug therapy in humans: studies with contraceptive steroids. AB - The effects have been studied of various environmental factors on the variability in response to oral contraceptive steroid therapy in women. Ten- to thirty-fold variations in plasma concentrations of norethisterone, L-norgestrel and ethinyloestradiol have been shown in samples taken 12 h after administration of oral contraceptives in mid-menstrual cycle. Factors shown to be responsible for this variation include passage into the enterohepatic circulation, a variable first-pass effect, and changes in metabolism in the gut wall or liver due to diet, disease, smoking or administration of drugs. Phenobarbitone and the antibiotic rifampicin increase both oestrogen and progestogen metabolism in women and in experimental animals by increasing hepatic and gut wall metabolism. In animals, other antibiotics (ampicillin, neomycin and lincomycin) suppress the gut flora that normally hydrolyse steroid conjugates excreted in bile; enterohepatic circulation or oral contraceptive steroids is thus reduced and their plasma concentrations lowered by up to 90%. In the human, ampicillin has a variable but less dramatic effect on elimination of oral contraceptives. Samples of gut wall mucosa obtained from patients with coeliac disease are defective in their ability to metabolize oral contraceptives. Cigarette smokers eliminate ethinyloestradiol more rapidly than non-smokers; an increased production of reactive steroid metabolites may thus be a cause of vascular disease in women who smoke and take contraceptive steroids. PMID- 6906268 TI - Induction of drug-metabolizing enzymes by polycyclic aromatic hydrocarbons: mechanisms, and some implications in environmental health research. AB - The mechanisms by which administration of polycyclic aromatic hydrocarbons (PAH) stimulates drug-metabolizing enzymes are summarized. The hepatic monooxygenase system of marine and freshwater fish is also induced by PAH-type compounds, including chlorinated dioxins and certain polychlorinated and polybrominated biphenyl isomers, and these chemicals are, or are suspected to be, toxic to humans. Consequently, there is considerable interest in whether or not PAH-type induction in fish can be used as a sentinel or early warning indicator for certain classes of toxic pollutants in the aquatic environment. We have investigated various aspects of PAH-type induction in marine fish and have found that approximately 50% of the winter flounder (Pseudopleuronectes americanus), captured near Mount Desert Island, Maine, appear to have induced hepatic monooxygenase systems, which suggests that they are exposed to PAH-type chemicals in the environment. The potential advantages and limitations of using PAH-type enzyme induction as a sentinel system for pollutants in aquatic ecosystems are discussed. PMID- 6906267 TI - Implications for future studies in humans. AB - While an environmental link with cancer is widely accepted, its implications are not always understood. Because of the multistage nature of carcinogenesis, it is insufficient to study initiation only at the level of the 'target cell', since events before and after initiation may prove pivotal to neoplastic development. Estimates of the relative contributions of factors causing human cancer are briefly summarized. Tumours related to patterns of life style--including diet and behaviour--and individual susceptibility are discussed. It is in this group of tumours that metabolizing enzymes are probably most significant, especially for weak initiating stimuli, whether extrinsic or intrinsic. There are few epidemiological data available at present but future research can be suggested, to improve the definition in biochemical terms of individual susceptibility and effects of life style. PMID- 6906269 TI - [Structure of tryptophanyl-tRNA synthetase and limited proteolysis products according to circular dichroism findings]. PMID- 6906272 TI - [Diuretic agents]. PMID- 6906271 TI - [Foreign bodies in the respiratory tract of children]. PMID- 6906270 TI - [Sodium fucidin treatment of pustular skin diseases]. PMID- 6906273 TI - [Drug incompatibility]. PMID- 6906274 TI - [Scientific organization of work in public health]. PMID- 6906276 TI - [New health education films]. PMID- 6906277 TI - [Sanitary hygiene conditions for work training of students in senior classes]. PMID- 6906275 TI - [Subject content for talks on preventing drunkenness and alcoholism]. PMID- 6906278 TI - [Routine sanitary control over school dining rooms]. PMID- 6906279 TI - [Primary atonic labor]. PMID- 6906280 TI - [Cancer of the ovaries]. PMID- 6906281 TI - [Treatment with mineral waters]. PMID- 6906283 TI - [Puerperal strain and rupture of the public symphysis]. PMID- 6906282 TI - [Prevention of caries with phytoncides]. PMID- 6906285 TI - [Hemangioma]. PMID- 6906284 TI - [Chronic pancreatitis]. PMID- 6906286 TI - [Obesity]. PMID- 6906287 TI - [Clinical assessment of urinalysis]. PMID- 6906288 TI - [Gynecological morbidity in workers of the furniture and wood-working industries]. PMID- 6906289 TI - [Detection, registration and curative treatment of the chronically and frequently ill]. PMID- 6906291 TI - [Poisoning with psychopharmacological action preparations]. PMID- 6906290 TI - [Dairy products and their role in nutrition]. PMID- 6906292 TI - [Material for talks on preventing hypertension (facts and figures)]. PMID- 6906293 TI - [Experience in eradicating ascariasis in the population]. PMID- 6906294 TI - [Chronic lympholeukemia]. PMID- 6906296 TI - [Amniotic fluid embolism complicated by uterine hemorrhage]. PMID- 6906295 TI - [Preinfarct state]. PMID- 6906297 TI - [Sclerocystic ovary syndrome]. PMID- 6906298 TI - [Foot-and-mouth disease]. PMID- 6906299 TI - [Rheumatoid arthritis]. PMID- 6906300 TI - Bouquets and a brickbat. PMID- 6906303 TI - The hardest decision. PMID- 6906302 TI - An SNF for BSN students. PMID- 6906301 TI - The plight of the elderly alcoholic. PMID- 6906304 TI - Deciding with the elderly. PMID- 6906305 TI - Rehabilitation for long term residents. PMID- 6906306 TI - Reflections: mirrors and the aged, a subject for study? PMID- 6906307 TI - A drug education program for the well elderly. PMID- 6906308 TI - Common concern: toward a stimulating retirement. PMID- 6906309 TI - Drugs and the elderly: when the patient is on diuretics. PMID- 6906311 TI - Isolation of an enzymatically active glandular kallikrein from human plasma by immunoaffinity chromatography. AB - A glandular kallikrein from human plasma was isolated by immunoaffinity chromatography and characterized. The molecular weight was determined to 40,000 by gel filtration. The enzyme preparation liberates kinins from human HMW kininogen (specific activity: 0.328 HMW kininogen-U/A280 unit), lowers the blood pressure of dogs after intravenous injection (specific activity: 1090 KE/A280 unit), is inhibited by diisopropyl fluorophosphate and aprotinin, but not by SBTI. In the radioimmunoassay for human urinary kallikrein parallel binding curves were obtained. AcPheArgOEt, DVal-LeuArgOEt and ZTyrONp are cleaved with identical rates by the kallikrein preparation and human urinary kallikrein. PMID- 6906310 TI - Nutrition: what can elders eat to prevent iron deficiency? PMID- 6906312 TI - Structure of the elastase-cathepsin G inhibitor of the leech Hirudo medicinalis. AB - The leech Hirudo medicinalis contains three different groups of proteinase inhibitor proteins, the thrombin-specific hirudin, the bdellins directed against trypsin, plasmin and acrosin, and the eglins which were discovered only recently. We are interested in the eglins mainly for two reasons: (i) They form strong complexes with the granulocytic elastase and cathepsin G with Ki values close to 1 x 10(-10) mol/l. Due to this property they are potential candidates for the therapeutic treatment of various diseases. (ii) Although the eglins do not contain a disulfide bridge to stabilize the tertiary structure, they are highly resistant to denaturation by acidification and by heat as well as to proteolytic degradation. PMID- 6906313 TI - A publication project at the undergraduate level. PMID- 6906314 TI - A study of the effects of teacher gender on learning. PMID- 6906315 TI - How professionalized is nursing? PMID- 6906316 TI - Why write, why publish? PMID- 6906322 TI - Working in other countries: a unique opportunity for American nurses. PMID- 6906320 TI - Culture, ethnicity, and the health care system. PMID- 6906317 TI - "Spouse abuse". PMID- 6906318 TI - Main motion: entry into practice. PMID- 6906321 TI - Minimizing your federal income tax. PMID- 6906323 TI - In nursing -- it's a small, small world. PMID- 6906319 TI - Health policy around the world. PMID- 6906324 TI - Missionary nursing in Honduras. PMID- 6906325 TI - The importance of touch in patient care. PMID- 6906326 TI - From graduate nurse to registered nurse. PMID- 6906327 TI - Helping patients help themselves! PMID- 6906328 TI - How to make friends with a hurricane. PMID- 6906329 TI - Isolation and characterization of rat complement factor B and its interaction with cell-bound human C3. AB - Factor B was isolated from fresh rat plasma by sequential chromatography on QAE A50, Biorex-70, gel filtration on Sephadex G-200 superfine and rechromatography on QAE-A50. That Brat was isolated in its native form was indicated by its migration during immunoelectrophoresis and by its capacity to react with cobra venom factor (CoVF) in the presence of human D to form a C3 convertase capable of cleaving purified rat C3 and human C3. The recovery of Brat was between 8 and 15%; the final material was homogeneous according to SDS-PAGE analysis. Reduction of Brat with DTT in the presence of urea and SDS did not produce detectable peptides of lower molecular weight. Both reduced and unreduced Brat had an apparent molecular weight of 100,000. An antiserum against Brat induced in rabbits recognized only one protein in fresh rat plasma as indicated by immunodiffusion and immunoelectrophoretic analysis. Zymosan treatment of rat serum resulted in the cleavage of Brat into two fragments with alpha and gamma mobility. Native Brat has a beta electrophoretic mobility. The plasma concentration of Brat in Wistar rats was 215 +/- 38 microgram/ml (mean +/- SD). PMID- 6906330 TI - Lymphocyte traffic through antigen-stimulated lymph nodes. I. Complement activation within lymph nodes initiates cell shutdown. AB - Complement activation within lymph nodes has been shown to alter lymphocyte traffic through the node. Challenge of cannulated sheep lymph nodes with either immune complexes or complement activators was found to initiate the phenomenon of cell shutdown associated with antigenic challenge of lymph nodes in primed animals. PMID- 6906331 TI - [Tetralogy of Fallot, a teaching plan]. PMID- 6906333 TI - [Original stomotherapy technics in the treatment of fistulas and ostomies]. PMID- 6906332 TI - [Coronary vasodilators: quiz]. PMID- 6906335 TI - [Industrial visit of Tioxide Inc...strict legislation]. PMID- 6906334 TI - [The Dollfuss-Mieg textile factories]. PMID- 6906336 TI - [Use of sleeping pills. A habit to be eliminated in the elderly]. PMID- 6906337 TI - [Legal aspects: nurse it's your fault!]. PMID- 6906338 TI - [Nursing the patient in his own setting]. PMID- 6906339 TI - [Nurses' approach to homosexuality]. PMID- 6906341 TI - [Patient transfer, a difficult enterprise]. PMID- 6906340 TI - [Helping relationship]. PMID- 6906342 TI - [The National Institute for Research and Safety]. PMID- 6906343 TI - [Nursing services at the Women's Show]. PMID- 6906344 TI - Innovative educational changes: a paradigm. PMID- 6906345 TI - Uncovering fear: group experience of nurses in a cancer ward. PMID- 6906346 TI - Attachment behavior of the Egyptian mother. PMID- 6906347 TI - Distress associated with menstruation among Israeli women. PMID- 6906348 TI - Methodological considerations in hospital patient opinion surveys. PMID- 6906350 TI - Community health aide programme in Jamaica. PMID- 6906349 TI - Action models for health centre staff. PMID- 6906351 TI - Current trends and issues in nursing in the United States: the primary health care nurse practitioner. PMID- 6906352 TI - Rehabilitation: core of nursing. PMID- 6906353 TI - Purification and characterization of urinary trypsin inhibitor, UTI68, from normal human urine, and its cleavage by human uropepsin. PMID- 6906355 TI - Principles of patient education for the patient with an altered neurological status. AB - Teaching patients with an altered neurological status is a difficult task but a task which is a priority to consider when planning patient care. The task can be accomplished as principles are considered, barriers are removed, and the process is adapted to meet the individual's needs. PMID- 6906354 TI - Characterization of initiation factor eIF-3 from wheat germ. AB - Initiation factor eIF-3 has been isolated from the 120 mM KCl postribosomal supernatant of wheat germ by chromatography on DEAE-cellulose and phosphocellulose. Glycerol gradient centrifugation and polyacrylamide gel electrophoresis under nondenaturing conditions indicate that the eIF-3 prepared in this manner is at least 85% pure. Polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate shows that the wheat germ eIF-3 contains 11 polypeptides, ranging in molecular weight from about 25,000 to 120,000. Eight of the polypeptides are present in equimolar amounts; two of the polypeptides are present at molar ratios of about 0.5; and one is present at a molar ratio of about 0.3. The highly purified wheat germ eIF-3 does not prevent the association of wheat germ 40S and 60 S ribosomal subunits to a significant extent. Wheat germ eIF-3 does not increase appreciably the ability of eIF-2 to form a ternary complex with Met-tRNAf and GTP. It does, however, enhance the binding of Met tRNAf to 40 S ribosomal subunits in the presence of eIF-2 and GTP. PMID- 6906358 TI - Development of a resource support system for nurses caring for spinal cord injured patients. PMID- 6906357 TI - Alternate programs of steroid administration for patients on long-term therapy. PMID- 6906356 TI - Nursing management of the patient with meningeal carcinomatosis. AB - The care of the patient with meningeal carcinomatosis is not unlike the care of any other patient. Despite varying symptomatology, the nurse views the patient holistically. The nurse helps the patient and family adjust to a disease process which at present, shows a gradual deterioration of function even with current therapy. PMID- 6906360 TI - Identifying brain tumors. PMID- 6906359 TI - Vasospasm secondary to subarachnoid hemorrhage: the current controversy, research, and nursing dilemmas. PMID- 6906361 TI - Prolactin secreting pituitary adenoma: a review and study of their implications for fertility in women. PMID- 6906362 TI - The differential diagnosis of headache and its nursing management. PMID- 6906364 TI - Voluntary standards--the USP and the PDA. PMID- 6906365 TI - Clarification of sterilization nomenclature. PMID- 6906363 TI - Comparative effects of antacids, enteric coating, and bile salts on the efficacy of oral pancreatic enzyme therapy in cystic fibrosis. PMID- 6906367 TI - Inspectional guidelines for sterile bulk antibiotics. PMID- 6906366 TI - Rubber stopper and component identification using syringeless gas chromatography. PMID- 6906368 TI - Review of excipients and pH's for parenteral products used in the United States. PMID- 6906369 TI - On the structural compatibilities of membrane filters. PMID- 6906370 TI - Use of the capacitance manometer gauge in vacuum freeze-drying. PMID- 6906372 TI - Anti-peptic ulcer agents--Part II. Single component antacids. PMID- 6906371 TI - Bioavailability of parenteral drugs II. Parenteral doses other than intravenous and intramuscular routes. PMID- 6906373 TI - It isn't senility: the nurse's role in Alzheimer's disease. PMID- 6906374 TI - Demystifying diagnostic procedures: stress testing. PMID- 6906375 TI - Dx: osteoporosis. Rx: patient teaching. PMID- 6906376 TI - Foot care for your diabetic patients. PMID- 6906377 TI - The woman in white: it's time to put the nurse back into that image. PMID- 6906378 TI - What drives nurses out of hospitals? PMID- 6906379 TI - So you always wanted to write about that patient who. PMID- 6906380 TI - Anti-peptic ulcer agents - Part III. Multiple component antacids. PMID- 6906381 TI - Easing the pain of peptic ulcers: the nurse's role in treatment and prevention. PMID- 6906382 TI - Peptic ulcers: on the front lines of research and treatment. PMID- 6906383 TI - Crisis: recognition and intervention are crucial nursing roles. PMID- 6906385 TI - The 1985 issue: are there more than two options? PMID- 6906384 TI - A taste of success. PMID- 6906386 TI - Caring for - and about - the elderly. PMID- 6906387 TI - The status of the LPN. PMID- 6906389 TI - Positive identification of patients. PMID- 6906388 TI - I never wear white after dark. PMID- 6906390 TI - Preparing for the interview. PMID- 6906391 TI - Maternity - the newborn. PMID- 6906392 TI - Update on mandatory continuing education. PMID- 6906393 TI - The beat goes on: television entertainment. PMID- 6906395 TI - [Births of infants with congenital abnormalities and assistance for their families: basic attitude of health personnel. A discussion]. PMID- 6906394 TI - [On the determination of plasma prekallikrein with chromogenic peptide substrate (author's transl)]. PMID- 6906397 TI - [Births of children with congenital anomalies and the role of the case worker]. PMID- 6906399 TI - [Births of children with external anomalies and their nursing (II). With special reference to hospitalization of a child with cleft lip and palate]. PMID- 6906396 TI - [outlines of the treatment of external anomalies and guidance of the parents - external anomalies of the skull and facial regions with special reference to cleft lip and palate and microtia]. PMID- 6906398 TI - [Births of children with external anomalies and their nursing (I). Nursing of a child with cleft lip and palate from the initial diagnosis to hospitalization]. PMID- 6906400 TI - [Congenital anomalies and genetic counseling]. PMID- 6906401 TI - [Comparative obstetrics in man and primates. 8. Sex and reproduction in primates (III)]. PMID- 6906402 TI - [Choice in disconnection of the respirator used to maintain the lives of severely handicapped newborn infants]. PMID- 6906403 TI - [A letter from the Philippines. (2)]. PMID- 6906404 TI - [History of sex therapy and related problems]. PMID- 6906405 TI - [Instances where sex counseling is needed]. PMID- 6906406 TI - [Health instructions concerning sexual activities and birth control]. PMID- 6906407 TI - [Assistance for the patients after extirpation of reproductive organs]. PMID- 6906408 TI - [Human sexuality in literature]. PMID- 6906409 TI - [Comparative obstetrics in man and primates. 9. Labor in primates. (V)]. PMID- 6906411 TI - [Therapeutic policies in breech presentation]. PMID- 6906410 TI - [Care of an expectant patient with primary hypothyroidism]. PMID- 6906412 TI - [Etiology and factors associated with the development of toxemia in the late stage of pregnancy]. PMID- 6906413 TI - [Classification and diagnosis of pregnancy toxemias]. PMID- 6906414 TI - [Methods of diagnosis of toxemias in the late stage of pregnancy]. PMID- 6906416 TI - [Management of pregnancy toxemias]. PMID- 6906415 TI - [Dietary instructions for patients with pregnancy toxemias]. PMID- 6906418 TI - [Conditions of pregnancy toxemias observed at our delivery section and future problems]. PMID- 6906417 TI - [Problems concerning health instructions for patients with toxemia in the late stage of pregnancy]. PMID- 6906420 TI - [Study on determination of bath temperature]. PMID- 6906419 TI - [Study of baby hotels (unlicensed infant nurseries) operated in Tokyo]. PMID- 6906422 TI - [Medical topics. The effects of hypothermia during the neonatal stage]. PMID- 6906421 TI - [Status of family planning in the Philippines]. PMID- 6906423 TI - [Obstetrical nursing reflected in child care]. PMID- 6906424 TI - [Various problems concerning case studies in clinical psychiatry]. PMID- 6906425 TI - [Meaning of negative data in medicine]. PMID- 6906426 TI - [Significance in learning from failures]. PMID- 6906427 TI - [Elimination of subjectivity from the estimation. A discussion]. PMID- 6906428 TI - [Care of a patient with difficulty in adapting to the hospital environment]. PMID- 6906429 TI - [Nursing of a child with postoperative complications and resultant brain damage - nursing assistance in weaning]. PMID- 6906430 TI - [Nursing with an objective - from an interaction with a patient with pre operative anxiety]. PMID- 6906431 TI - [Changes in nursing technics in association with progress of medicine and medical technics - skin disinfection]. PMID- 6906432 TI - [Unforgettable encounter: an experience in nursing of a premature infant]. PMID- 6906434 TI - [Essay on nursing education. A thought having undergone a critical stage in an illness: re-evaluation and questions on nursing and nursing education]. PMID- 6906436 TI - [Planning of training in obstetrical nursing (3). Clinical training in nursing of puerperal patients]. PMID- 6906435 TI - [Developments in practical training by "visiting patients"]. PMID- 6906433 TI - [Philosophical notes on nursing theory]. PMID- 6906437 TI - [Trial in a seminar for clinical nursing instructors: for recognition of problems in a process of self-development]. PMID- 6906438 TI - [Experience in pediatric nursing at the Royal Brisbane Children's Hospital]. PMID- 6906440 TI - [Concept of a regional community, public health, and medical care]. PMID- 6906439 TI - [Scenes with illness. 12. Experiences as a local practitioner]. PMID- 6906441 TI - [Trends involving public health nurses and future problems]. PMID- 6906442 TI - [On food additives. Discussion]. PMID- 6906443 TI - [Problems of the aged and public health nursing activities]. PMID- 6906444 TI - [School health and regional health]. PMID- 6906446 TI - [Health promotion plans and public health nursing activities. A discussion]. PMID- 6906445 TI - [Public health nursing education. A discussion]. PMID- 6906447 TI - [Health problems of workers. A discussion]. PMID- 6906448 TI - [Public health and the significance of public health statistics]. PMID- 6906449 TI - [Efforts toward 50 percent reduction and eventual total elimination of infant mortality in Iwate Prefecture]. PMID- 6906451 TI - [The role of public health nurses working for municipal governments]. PMID- 6906450 TI - [Structures of public health budgets and methods for requesting these budgets]. PMID- 6906452 TI - [Meal services for the aged at Matsubara-shi - the role of the public health clinic. Symposium]. PMID- 6906454 TI - [Excessive diversification in public health nursing: an observation by the nurses transferred from Tokyo]. PMID- 6906453 TI - [Full utilization of the public health clinic: public health activities in Hokkaido and their problems. Isolation from the public: an observation by a public health nurse transferred from Tokyo]. PMID- 6906455 TI - [Need for cooperation among public health nurses--improved activities with common ideals and joint efforts. A discussion]. PMID- 6906457 TI - [Public health activities responding to the public needs--planning of need oriented activities]. PMID- 6906456 TI - [Re-evaluation of functions of midwives in regional health activities. A question on their roles as primary health workers]. PMID- 6906458 TI - [Toward creation of a healthy and affluent village--health activities of the Kamigo Health Center]. PMID- 6906459 TI - [Assistance in application of a bed pan. (2)]. PMID- 6906460 TI - [The nursery school teacher and the public health nurse]. PMID- 6906461 TI - Editorial. PMID- 6906462 TI - Effects of cigarette smoking on maternal nutrition and the fetus. AB - Available evidence supports the importance of including facts about smoking and pregnancy in all teaching to women in the childbearing years. The incidence of low birthweight infants is possibly almost twice as high among smoking mothers, and these low birthweight babies are known to be at risk on several counts. Compromised utilization of vitamins and minerals is presented as a causative factor: calcium, vitamin B12, and vitamin C levels are lower in smokers. Other vitamin levels may be affected. Poor nutrition and other factors connected with smoking may result also in stillbirths, spontaneous abortions, congenital anomalies, and cancer in the offspring. Nurses have a unique opportunity to contribute to maternal-child health by teaching and counseling about smoking in pregnancy. PMID- 6906463 TI - Nursing and medical students' sexual attitudes and knowledge. Curricular implications. AB - Sexual attitudes and knowledge of graduate nursing students were compared with those of sophomore medical students in a large, urban Midwestern university and also with the national normative values for nonmedical graduate students. The Sex Knowledge and Attitude Test (SKAT) was used to collect data. Graduate nursing students did not differ significantly in the attitude and knowledge of human sexuality when compared with sophomore medical students. Graduate nonmedical students were not significantly more knowledgeable, but were significantly more tolerant toward human sexuality than sophomore medical students and graduate nursing students. The fundamental implication is the need for more constructive education in human sexuality as a planned part of the nursing curricula. PMID- 6906464 TI - Obstetrical nurses' attitude toward fetal monitoring. AB - A 24-item tool, using a Likert attitudinal scale, was developed to measure labor and delivery nurses' attitudes toward fetal monitoring and was administered to 124 nurses. For each of the 24 attitude statements, cumulative responses were over 50% positive at least. Fifty-two percent of the nurses felt that routine continuous monitoring of all labor patients would be ideal, and 88% felt that the fetal surveillance achieved by monitoring cannot be matched by intermittent auscultation. PMID- 6906465 TI - Patient acceptance of fetal monitoring as a helpful tool. AB - In 1972, 50 women on a postpartum unit were interviewed to investigate responses to fetal monitoring. Not one woman interviewed had a positive initial response; 31 women had negative initial responses. In 1977, in a replication of the study, 11 women had positive initial responses, 11 had negative initial responses, and 28 had neutral initial responses. Two significant findings: 1) older women initially reacted more positively to fetal monitoring than younger women; and 2) married women initially reacted more positively to fetal monitoring than single women. This indicates a need for nurses to be more sensitive to young, single women's initial responses to fetal monitoring. In the 1977 study subsequent responses were 37 positive, 4 negative, and 9 neutral. PMID- 6906466 TI - Basics of breastfeeding. Part V. Self-care for continued breastfeeding. AB - The advantages of continuing breastfeeding beyond the neonatal period are reviewed and general guidelines for self-care at home are discussed. Developmental changes in the infant and psychological and physical changes in the mother are outlined and related to breastfeeding success. Advice for working mothers and for weaning is also presented. PMID- 6906467 TI - Basics of breastfeeding. Part VI. Some breastfeeding problems and solutions. AB - Management of several potential physical problems is presented: sore breasts, engorgement, leaking, breast infections, nipple damage, and thrush. Then problem solving for the separated mother and breastfeeding infant, genetic abnormalities, and slow weight gain are discussed. The final sections deal with maternal medication and environmental contaminants in breast milk. PMID- 6906468 TI - The structure and function of brown adipose tissue in the neonate. AB - Presented is a discussion of brown adipose cell structure as compared to that of the white adipose cell, the role which brown adipose tissue (BAT) plays in thermoregulation, the physiologic mechanisms which control BAT heat generation, and the proposed biochemical processes which are responsible for heat production in the cell. Based on the physiology of BAT thermogenesis, specific nursing measures to minimize cold stimuli are recommended. PMID- 6906469 TI - Nursing care for the relinquishing mother. AB - Unmarried adolescents with unplanned pregnancies face, along with the usual physiologic and psychologic changes, parental force and/or peer pressure to leave home and live elsewhere and a decision about the relinquishment of the infant. An important figure during the parental and immediate postpartum periods is the nurse. Nursing care required by relinquishing mothers is outlined and recommendations are given. PMID- 6906471 TI - [Impression on the 2nd International Oncology Nursing Congress]. PMID- 6906470 TI - Parenting: are NIC nurseries meeting the challenge? PMID- 6906472 TI - [The Old People's Town and the aged population (a large nursing home complex in Copenhagen)]. PMID- 6906474 TI - [Statistics on the graduates of nursing schools]. PMID- 6906473 TI - [Nursing focal point in grasping the patient's personality]. PMID- 6906475 TI - [The modern attitude of children to their parents]. PMID- 6906476 TI - [Understanding the patient's psychology]. PMID- 6906477 TI - [The weight of the personality column in the patient record in understanding the patient--on the often-used expression, "nervous"]. PMID- 6906479 TI - [Understanding of patients' personality--changes of the image in interpersonal relationship]. PMID- 6906480 TI - [Sexuality in the aged. (11)]. PMID- 6906478 TI - [What are the "personality" and "grasping the personality"?]. PMID- 6906481 TI - [Controversies in primary health care: a suggestion on the implementation of primary health care in Japan (a)]. PMID- 6906483 TI - [Liver cancer and water]. PMID- 6906482 TI - [Profile of a nurse. Ms. Kayoko Shimizu, the 5th head of the Nursing Section, Ministry of Health and Welfare]. PMID- 6906484 TI - [Synergistic action of various types of asbestos in carcinogenesis]. PMID- 6906485 TI - [Sudden infant death syndrome]. PMID- 6906486 TI - Effects of sodium orthovanadate on whole kidney and single nephron function. AB - The renal effects of sodium vanadate (Na3VO4), an inhibitor of sodium-potassium ATPase recently shown to be a potent diuretic, were studied by using clearance and micropuncture techniques in nondiuretic anesthetized rats. Administration of 1.0 mumole of sodium vanadate (high dose) increased urine flow rate (V) from 9.8 +/- 1.4 to 17.5 +/- 4.0 microliter/min (mean +/- SEM, P < 0.025), UNaF from 1.73 +/- 0.36 to 3.05 +/- 0.65 microEq/min (P < 0.025), and FENa from 0.67 +/- 0.15 to 1.24 +/- 0.28% (P < 0.025)., No significant changes in GFR or RPF were observed. Late proximal tubular-fluid-to-plasma (F/P) inulin decreased from 2.28 +/- 0.19 to a minimum value of 1.38 +/- 0.06 (P < 0.025). Absolute water reabsorption decreased from 15.8 +/- 3.5 to 6.5 +/- 1.7 nl/min (P < 0.025) and fractional water reabsorption from 52.0 +/- 4.4 to 26.5 +/- 4.1% (P < 0.025). The injection of 0.5 mumole of sodium vanadate (low dose) resulted in no significant changes in V. Late proximal F/P inulin decreased, however, from 2.37 +/- 0.14 to a minimum value of 1.59 +/- 0.12 (P < 0.025). SNGFR remained unchanged, as did GFR and RPF. UNaV increased from 1.41 +/- 0.35 to 2.25 +/- 0.35 microEq/min (P < 0.025), and FENa rose from 0.64 +/- 0.16 to 0.91 +/- 0.15% (P < 0.025). The decrease in F/P inulin was observed in all but one animal, even in the absence of a diuretic response. The amount of fluid remaining in the lumen of the late proximal tubule was virtually the same in both low- and high-dose animals (18.9 +/- 3.0 and 19.5 +/- 3.4 nl/min, respectively). We conclude that sodium vanadate causes a decrease in superficial proximal tubule fluid and salt reabsorption. Inasmuch as the low dose does not result necessarily in a diuretic response, an increase in fluid reabsorption distal to the late proximal tubule must take place. PMID- 6906487 TI - [Plasma kininogenesis in acute pancreatitis]. PMID- 6906488 TI - [Use of depot kallikrein for preventing liver necrosis in ligation of the end branches of the hepatic artery proper]. PMID- 6906489 TI - President's pen: the current nursing shortagae. PMID- 6906490 TI - The who, what, when, why and how of professional negotiations for nurses. PMID- 6906491 TI - Environmental effects on children's hearing: how can school systems cope? AB - Physical, social and psychological environments have had substantial impact on the hearing efficiency of American youth. During the neonatal, preschool and school years, environmental factors such as injuries, drugs, fractures, noise, viruses and Rh incompatibility have exposed youth to auditory damage. School administrators can plan and should implement acoustical measures in the design of their school buildings and screening programs. Teachers can learn to practice communication techniques that result in more effective education for those students with hearing losses as well as those who hear normally. PMID- 6906492 TI - Project superheart: an evaluation of a heart disease intervention program for children. PMID- 6906494 TI - Toward understanding stress: a map of the territory. PMID- 6906493 TI - Student delivery of health services to students: a longitudinal analysis. PMID- 6906497 TI - Epilepsy workshop for public school personnel. PMID- 6906496 TI - Lead poisoning in children, a persistent disease of industrialized society, and be prepared to take action should they encounter it. PMID- 6906495 TI - More about stress and some management techniques. PMID- 6906498 TI - Health career training in high school: the magnet concept. PMID- 6906499 TI - How will it affect children? The need for child advocacy process and policy. PMID- 6906500 TI - Selected health beliefs of Vietnamese refugees. PMID- 6906502 TI - [Significance of nursing research conducted in the hospital]. PMID- 6906501 TI - Nurses and nurse practitioners in schools. PMID- 6906503 TI - [Hospital seminar as part of in-service training--introduction of a program]. PMID- 6906505 TI - [Lessons from case studies]. PMID- 6906504 TI - [Nursing seminar on the revision of nursing records]. PMID- 6906506 TI - [The current status and problems of the in-service study group--from the viewpoint of the personnel in charge of training]. PMID- 6906509 TI - [Primary health nursing in England. 5. Evolution of a team approach]. PMID- 6906507 TI - [Visitor education program by the United Ostomy Association]. PMID- 6906508 TI - [Bedside conference in pediatric nursing. 8. Nursing in hematologic diseases (No. 4), malignant tumors (No. 2), immunologic deficiency, and a psychophysiologic disorder]. PMID- 6906510 TI - [Reminiscence in nursing education]. PMID- 6906512 TI - [A program for a joint study by the nursing staff and students--a thought on comprehensive training]. PMID- 6906511 TI - [Teacher/student relationships]. PMID- 6906513 TI - [Nursing process/nursing of a patient with multiple sclerosis. Description of multiple sclerosis]. PMID- 6906514 TI - [Nursing process/nursing of a patient with multiple sclerosis. Treatment of multiple sclerosis]. PMID- 6906515 TI - [Nursing process for patients with multiple sclerosis. I. Clinical history and diagnosis. II. Nursing process from the time of hospital admission to tracheotomy. III. Nursing process after tracheotomy to admission to the ICU. IV. Nursing process from the release from the ICU to the start of rehabilitation and training. Evaluation of the nursing process]. PMID- 6906516 TI - [Medication and management of drugs]. PMID- 6906517 TI - [Nursing technology concerning medication]. PMID- 6906518 TI - [Postoperative drip infusion and its care]. PMID- 6906519 TI - [Methods and care in oxygen therapy]. PMID- 6906520 TI - [Nursing care associated with oxygen inhalation therapy]. PMID- 6906521 TI - [Nursing of an alcoholic patient and the nursing personnel]. PMID- 6906522 TI - [A superficial image and the real nature of nursing practice]. PMID- 6906523 TI - [Basis of the contact with patients. (1)]. PMID- 6906524 TI - [Basis of the contact with patients. (2)]. PMID- 6906525 TI - [Nursing process / nursing of patients with leukemia. Description of leukemia - with special reference to physiopathology]. PMID- 6906526 TI - [Nursing process / nursing of patients with leukemia. Diagnosis and treatment of leukemia]. PMID- 6906527 TI - [Physiology of defecation and indication for the use of an enema]. PMID- 6906529 TI - [Enema therapy for patients with colostomy]. PMID- 6906530 TI - [Application of endoscopy]. PMID- 6906528 TI - [Keypoints in nursing care associated with enema therapy - scientific and safe application of an enema]. PMID- 6906531 TI - [Assistance and care during endoscopic examination. (1)]. PMID- 6906532 TI - [Nursing of a patient in a vegetative state and the nursing personnel]. PMID- 6906533 TI - [Nursing action reaching the depth of the patient's emotion]. PMID- 6906534 TI - [Innovation in the prevention of decubitus ulcer]. PMID- 6906535 TI - [Description of rectal cancer - an increase in the incidence of rectal cancer]. PMID- 6906536 TI - [Nursing process for the colostomy patient (with rectal cancer)]. PMID- 6906537 TI - [Nursing process/nursing of patients with rectal cancer. Problems in nursing planning. A discussion]. PMID- 6906538 TI - [Massage and its significance]. PMID- 6906539 TI - [Massage as a nursing technology]. PMID- 6906540 TI - [Humanistic significance of touching]. PMID- 6906541 TI - [Practice of endoscopy]. PMID- 6906542 TI - [Assistance and nursing care in endoscopic examination. (2)]. PMID- 6906543 TI - [Assistance of the blind and the nursing personnel]. PMID- 6906544 TI - [New nursing philosophy. III. Action toward awakening the lost sensitivity]. PMID- 6906545 TI - [Pain: a case report]. PMID- 6906546 TI - [Test yourself: nursing of a child with esophageal atresia]. PMID- 6906547 TI - [A physician's experience in hospitalization]. PMID- 6906549 TI - Effective letter-writing to your legislators. PMID- 6906548 TI - Effective grievance processing--Part I. PMID- 6906550 TI - An impossible dream? PMID- 6906551 TI - Women and employment. PMID- 6906552 TI - Critical stress. PMID- 6906553 TI - On grief. PMID- 6906554 TI - Fetal heart rate monitoring (continued from November Issue). PMID- 6906555 TI - The nurse: the modern day Spartan. PMID- 6906556 TI - The New South Wales College of Nursing Annual Oration and Investiture of Fellows and Members 17th September, 1980. PMID- 6906557 TI - Educating for clinical excellence. PMID- 6906558 TI - Fact sheet--House Bill 4250. An act providing reimbursement for services of certain health care providers. PMID- 6906559 TI - [Infertile marriage]. PMID- 6906560 TI - [Ejaculate study]. PMID- 6906561 TI - [Adrenogenital syndrome]. PMID- 6906562 TI - [Changes in the urinary system during pregnancy and in gynecologic diseases]. PMID- 6906563 TI - [Prodigiozan treatment of chronic inflammatory processes in the uterus and adnexa]. PMID- 6906564 TI - [Work organization in gynecological consultation]. PMID- 6906565 TI - [Drug anesthesia of labor]. PMID- 6906566 TI - [Care by medical workers for the young family]. PMID- 6906567 TI - [Women's personal hygiene room in a plant]. PMID- 6906568 TI - [Comprehensive health promotion and the treatment of children: a guarantee of the work effectiveness of a specialized preschool institution]. PMID- 6906569 TI - [Reflexotherapy]. PMID- 6906570 TI - [Trichomoniasis of the urogenital organs in women]. PMID- 6906572 TI - [Hygiene for the young girl (material for talks)]. PMID- 6906571 TI - [Measures to improve health protection and decrease child morbidity in preschool institutions of the Lithuanian SSR]. PMID- 6906573 TI - [Outpatient service for pregnant and puerperant women]. PMID- 6906574 TI - [Congenital cleft upper lip and palate]. PMID- 6906575 TI - [Outpatient care after gastric resection]. PMID- 6906576 TI - [Physiotherapy in deep burns]. PMID- 6906577 TI - [Medical gymnastics in Perthes' disease]. PMID- 6906578 TI - [Work organization for the clinical nurse in a burn ward]. PMID- 6906581 TI - [Eye lesions in cardiovascular pathology]. PMID- 6906580 TI - [Experience with using improved electrodes]. PMID- 6906579 TI - [Prevention of postinjection abcesses of the buttocks]. PMID- 6906582 TI - [Work experience of a people's university of health for senior students]. PMID- 6906583 TI - [Results of immunoprophylaxis with Soviet vaccinal preparations (IV)]. PMID- 6906584 TI - [Work of the head nurse in raising the level of patient care]. PMID- 6906585 TI - [Work organization in polyclinical department registration]. PMID- 6906586 TI - [Role of the district nurse in outpatient polyclinical care]. PMID- 6906587 TI - [Organization of health education work]. PMID- 6906588 TI - [Tutorial system experience]. PMID- 6906589 TI - [Tutorial system is a noble matter]. PMID- 6906590 TI - [Duty of the senior nurses]. PMID- 6906592 TI - [Professional skills competition]. PMID- 6906591 TI - [Competition for the title of "Best Nurse" at Donetsk Province Trauma Hospital]. PMID- 6906593 TI - [Lesions of the eye]. PMID- 6906594 TI - A new look at childbirth in the Netherlands. PMID- 6906595 TI - The best of both worlds. PMID- 6906596 TI - It's not so frightening if there are teddy bears in the corridor. PMID- 6906597 TI - Visit to a divided city. PMID- 6906598 TI - A preliminary report on the research project on the role and responsibilities of the midwife: Part 1. PMID- 6906599 TI - 26th Sir William Power Memorial Lecture. A quarter of a century of progress--but the perinatal mortality rate is still too high! PMID- 6906601 TI - Nursing research: the basis of clinical decisions. PMID- 6906600 TI - President's message. Nursing as a profession. PMID- 6906602 TI - Health promotion discussion groups for older adults. PMID- 6906603 TI - A study of the utilisation of the nursing process in operating theatre nursing in the United States and Canada. PMID- 6906604 TI - The marriage of national health insurance and la medicine liberale in France: a costly union. AB - In France, as in the United States, the problems of controlling health care costs are seemingly intractable. The incongruity of private provision with public financing is traced to adherence to competing and contradictory policies solidarity and liberal-pluralism. This "marriage" of ideologies has been costly, and efforts to stem rising prices have resulted in political stalemate. PMID- 6906606 TI - Washington focus. PMID- 6906607 TI - "A campaign for men". PMID- 6906608 TI - The not-so-obvious limits of nursing. PMID- 6906605 TI - Advantages and limitations of explicit criteria for assessing the quality of health care. AB - Explicit criteria for assessing the quality of health care should appeal to practitioners because such criteria make possible consistent judgments, openly arrived at. The process of their formulation encourages more critical scrutiny of current practice, identifying what the generality of practitioners can accept, and what is still doubtful. But, as instruments of social control, explicit criteria are a two-edged sword-vehicles for the best that medicine can offer, or instruments of institutionalized and pervasive error. Therefore, it is important to see who controls the criteria, whose perspectives and interests they serve, and what images of quality they render at once concrete and dominant. PMID- 6906610 TI - Preventing reality shock: one AD program's plan. PMID- 6906609 TI - Toward an understanding of accreditation practices. PMID- 6906611 TI - Patient classification systems: the problems faced. PMID- 6906612 TI - Accountability, review boards, and the lay participant. PMID- 6906613 TI - Nurses in action. PMID- 6906614 TI - The "good" patient. PMID- 6906615 TI - Some hidden costs of primary nursing. PMID- 6906616 TI - The post-natal period: a time of change. PMID- 6906617 TI - The baby's needs. PMID- 6906618 TI - Neonatology. PMID- 6906619 TI - Alternatives to a mothers care. PMID- 6906620 TI - Health visiting and post-natal care. PMID- 6906621 TI - Going home. PMID- 6906622 TI - Feeding from birth to 18 months. PMID- 6906623 TI - Play with babies and small children. PMID- 6906624 TI - Common problems and their management. PMID- 6906625 TI - Managing common behavioural problems. PMID- 6906626 TI - Peter, a premature baby. PMID- 6906627 TI - Legionnaires' disease: facts and fancies. PMID- 6906628 TI - Ergonomics: made to measure. PMID- 6906629 TI - First aid: answering the call at work. PMID- 6906630 TI - Counselling: the case for the specialist. PMID- 6906632 TI - What is epidemiology? PMID- 6906631 TI - Safety: by any other name. PMID- 6906633 TI - Ergonomics: the mechanics of man. PMID- 6906634 TI - The hazards of screening. PMID- 6906635 TI - Safety: fire-prevention and control. PMID- 6906636 TI - Control and prevention in occupational health: the nurse's role. PMID- 6906638 TI - Why objectives? Relationship to occupational health nursing practice. PMID- 6906637 TI - Is noise a potential hazard to pregnancy? PMID- 6906640 TI - Prenatal preparation: an industrial application. PMID- 6906639 TI - On teaching breast self-examination. PMID- 6906641 TI - Wellness, the worker and the nurse. PMID- 6906642 TI - Basic epidemiology for occupational health nurses. PMID- 6906643 TI - Legislators speak out on nursing, health care. PMID- 6906644 TI - Inflation ravages dues dollar value. PMID- 6906645 TI - Nursing shortage 'myths' busted. PMID- 6906646 TI - A nursing diagnosis taxonomy for quality assurance and reimbursement. Part I. PMID- 6906647 TI - Pediatrics ward, Khao-i-Dang. PMID- 6906648 TI - Keynote Address: "Unity and diversity: partners in the '80's". PMID- 6906649 TI - Reimbursement for nursing services. Part II. PMID- 6906650 TI - Toilet training: ready or not? PMID- 6906651 TI - Mothers of adolescent mothers: how do they cope? PMID- 6906652 TI - Adolescent consent: questions, confusion and conflicts. PMID- 6906654 TI - Teaching history-taking and interviewing skills to PNPs. PMID- 6906653 TI - Update: mandatory continuing education. PMID- 6906655 TI - Pediatric management problems: frostbite. PMID- 6906656 TI - Nurses' exchange: announcing your practice. PMID- 6906657 TI - Breast-feeding the adopted newborn. PMID- 6906659 TI - Beyond self-help. The underlying assumptions of paperback therapy. PMID- 6906658 TI - Community mental health consultation in police court. PMID- 6906660 TI - Nursing care of patients on lithium. PMID- 6906661 TI - The nucleotide sequence of a small (3S) seryl-tRNA (anticodon GCU) from beef heart mitochondria. AB - The primary structure of a 3S serine tRNA from beef heart mitochondria has been determined using our new two-dimensional "read-off" sequencing method (Tanaka, Y., Dyer, T.A. and Brownlee, G.G (1980) Nucleic Acids Res. 8, 1259-1272). When arranged in the "cloverleaf" form it shows unique features since (i) it completely lacks the dihydrouridine arm, (ii) it has an extended "T gamma" loop, but lacks the T and gamma residues, and (iii) it has only one minor base, N6(N threonylcarbamoyl)adenosine, next to the anticodon. PMID- 6906663 TI - Sounding board: in support of part-time faculty. PMID- 6906664 TI - Mutual interaction: a model of nursing practice. PMID- 6906662 TI - A mammalian mitochondrial serine transfer RNA lacking the "dihydrouridine" loop and stem. AB - A unique transfer RNA has been identified in human and bovine mitochondria that lacks the "dihydrouridine" loop and stem structure. This tRNA is mitochondrially coded as shown by DNA sequence analysis of the human and bovine mitochondrial DNA. Sequence analysis of the RNA shows that it is post-transcriptionally modified by the addition of CCA at the 3' terminus and that at least one base is modified. As predicted by its anticodon (GCU, corresponding to the serine codons AGU/C) this tRNA can be aminoacylated with serine when purified mitochondria are incubated in a medium containing 3H-serine. PMID- 6906665 TI - Students' adaptation according to Roy. PMID- 6906666 TI - A case for collaboration. PMID- 6906667 TI - Faculty development activities. PMID- 6906668 TI - Nurse Clones for sale. PMID- 6906669 TI - Deans of nursing: changing socialization patterns. PMID- 6906670 TI - The alcoholic nurse. PMID- 6906671 TI - Hospitals should do the sick no harm. 12. Controlling infection by isolation - 2. PMID- 6906673 TI - Thanks, Nurse, you did care more. PMID- 6906672 TI - Dying children at home. PMID- 6906675 TI - Taking to the waters of Israel: the curative springs of Tiberias. PMID- 6906674 TI - A plant for Sam. PMID- 6906676 TI - Producing a programme on videotape and taking care of the equipment. PMID- 6906677 TI - Recruitment-14. Initiatives in nursing recruitment. PMID- 6906678 TI - Systems of life No. 73. Systems and signs: respiration - 3. Auscultation. PMID- 6906679 TI - Motor neurone disease. PMID- 6906681 TI - Standards of nursing care. PMID- 6906682 TI - A new aid to geriatric nursing. PMID- 6906680 TI - Communication in nursing. PMID- 6906683 TI - Nursing care study: a New Year's Day baby. PMID- 6906684 TI - Health visitor to university student. PMID- 6906685 TI - Cleggs, frogs and Briggs: 1980 reviewed. PMID- 6906687 TI - Ward sister training. PMID- 6906686 TI - Behaviour modification. PMID- 6906688 TI - Spreading the word. A recent convention on the nursing process held in Saudi Arabia. PMID- 6906689 TI - Resolution realized. Kiss a non smoker...enjoy the difference! PMID- 6906690 TI - Feeding the hungry. From bedside nursing to digging latrines. A method of approaching problems of health and disease in refugee camps. PMID- 6906691 TI - The recruitment and training of volunteers for emergency relief work. PMID- 6906693 TI - Working at a camp in Thailand. PMID- 6906692 TI - Selective feeding procedures. PMID- 6906694 TI - Community nursing care study. A patient who wanted to die at home. PMID- 6906697 TI - Self-help. PMID- 6906695 TI - Learn before you practice. A training programme for nurses to administer intravenous additives. PMID- 6906696 TI - How am I doing as a health teacher? PMID- 6906698 TI - Changing the face of geriatric care. PMID- 6906699 TI - Meet 'Dr Hypothermia'. Interview by Lawrence Dopson. PMID- 6906700 TI - Nursing care study: Batten's disease. PMID- 6906701 TI - Management of a temporary colostomy. PMID- 6906702 TI - Ireland looks to the future. PMID- 6906703 TI - The nurse and the patient: communication skills. Introduction to communication. PMID- 6906704 TI - Experience with the Rhys Hearn geriatric workload package--a regional survey. PMID- 6906705 TI - The battle of Hastings. PMID- 6906706 TI - Where angels fear. PMID- 6906707 TI - The patient process. PMID- 6906708 TI - Community nursing care study: the ups and downs in the life of Betty. PMID- 6906709 TI - The bridge-builders' guide--1. PMID- 6906711 TI - Stress and anxiety in physical illness--the role of the general nurse. PMID- 6906710 TI - Precious eyesight. PMID- 6906712 TI - Three non-overlapping shifts in a neonatal unit--can it work? PMID- 6906713 TI - Medical notes--whose secrets? PMID- 6906714 TI - Finding nurses for the future. PMID- 6906715 TI - Nursing, education and research. PMID- 6906718 TI - Nursing staff for the mental and mental deficiency fields in Scotland. PMID- 6906717 TI - Finding nurses for the future. 3. Points of view.. Interview by Sheila Collins. PMID- 6906716 TI - Finding nurses for the future. 1. The recruitment and selection of nurse learners. PMID- 6906719 TI - Some lessons worth learning. PMID- 6906720 TI - Nursing care study: malignant melanoma. PMID- 6906721 TI - Self-referral to an accident and emergency department. PMID- 6906722 TI - Frequency of drug overdose. PMID- 6906723 TI - Care without carrying: looking after the elderly in residential homes. PMID- 6906724 TI - Nurses as home matrons. PMID- 6906726 TI - Systems of life No 74. Systems and signs: lymph nodes, the breast. PMID- 6906725 TI - Divine intervention? PMID- 6906727 TI - Health and the family. PMID- 6906728 TI - Medication compliance--a factor in the drug wastage problem. PMID- 6906729 TI - Working to a deadline: 37 1/2--hour week. PMID- 6906730 TI - Sharing some solutions. PMID- 6906731 TI - The genetics of cancer--1. PMID- 6906732 TI - Nursing care study: testicular teratoma. PMID- 6906733 TI - An experience of the nursing process. PMID- 6906734 TI - A prescription chart survey. PMID- 6906735 TI - A new service for parents with crying babies. PMID- 6906737 TI - First impressions. PMID- 6906736 TI - The behavioural approach to nursing the elderly. PMID- 6906738 TI - Change for the better. PMID- 6906740 TI - Do-it-yourself medicine--1. PMID- 6906739 TI - 'The creaks are now becoming cracks'. PMID- 6906741 TI - Nursing care study: behavioural treatment of an agoraphobic. PMID- 6906742 TI - The genetics of cancer-2. PMID- 6906744 TI - Aftercare in mourning. PMID- 6906743 TI - Venereology. PMID- 6906745 TI - Theories and concepts. PMID- 6906746 TI - The gentle touch... could we... should we? PMID- 6906747 TI - Choosing and using post-basic clinical training. PMID- 6906748 TI - Guide lines for a public relations programme for national nurses associations in membership with ICN. PMID- 6906749 TI - Research orientations in nursing--XIX. Why do I need theory. PMID- 6906751 TI - The role of medical social worker in the medical record department. PMID- 6906750 TI - Care of mentally ill patients. PMID- 6906752 TI - Anxiety neurosis. PMID- 6906753 TI - An evaluation of nutritional knowledge of nursing students. PMID- 6906754 TI - Research orientations in nursing--XXI. Writing a research report--how do I begin. PMID- 6906755 TI - Nursing: thoughts on nursing service and identification of the service offered- II. PMID- 6906756 TI - Review of 1980: look back in uncertainty. PMID- 6906757 TI - Arthritis: a joint approach. PMID- 6906758 TI - Mastectomy: facts and figures. PMID- 6906759 TI - Nursing in India. 2. Breaking with tradition. PMID- 6906760 TI - Research. 1. The numbers game. PMID- 6906761 TI - Nursing care study. Tetanus: the problem lies in the soil. PMID- 6906762 TI - Stay with the patient, expert nurse. PMID- 6906763 TI - Arabian nightingales. PMID- 6906764 TI - Rickets. 1. An old enemy returns. PMID- 6906765 TI - Research. 2. Checking vital statistics. PMID- 6906766 TI - Nurses and publishing: blood, sweat and tears. PMID- 6906767 TI - Cambridge Medical Answering Services: message received - over and out! PMID- 6906768 TI - Health and colours: looking in the pink. PMID- 6906769 TI - Research: hitches, hurdles and hopes. PMID- 6906770 TI - Biochemistry: antibodies - source and supply. PMID- 6906771 TI - Communication with the elderly: a good gossip goes a long way. PMID- 6906772 TI - International Conference on Cancer Nursing. 7. Give us our daily care. PMID- 6906773 TI - Nursing care study. Guillain-Barre syndrome: fading away. PMID- 6906774 TI - A complicated case: brain damage caused by forceps delivery. PMID- 6906775 TI - Save your own breath--and time! PMID- 6906776 TI - Sexually transmitted diseases: opening doors. PMID- 6906777 TI - Rickets. 2. Measure of success. PMID- 6906778 TI - Interviews: everything you wanted to know. PMID- 6906779 TI - Psychiatry and endocrinology: it's all in the glands. PMID- 6906780 TI - Education: carry on learning. PMID- 6906781 TI - Nursing care study. Community: my crabbit old woman. PMID- 6906782 TI - Management. Decision-making: how to make up your mind. PMID- 6906783 TI - Nursing care study. Cystic fibrosis: getting it off your chest. PMID- 6906784 TI - Where have all the tutors gone? PMID- 6906785 TI - Clinical forum: urological emergencies. Urinary tract infection. PMID- 6906786 TI - Clinical forum: urological emergencies. Griping about renal colic. PMID- 6906787 TI - Clinical forum: urological emergencies. Haematuria. PMID- 6906788 TI - Clinical forum: urological emergencies. When once is not enough. PMID- 6906789 TI - Clinical forum: urological emergencies. Childhood problems. PMID- 6906792 TI - Lay midwifery in USA. Labour force. PMID- 6906790 TI - Black stockings and bed baths; the public's opinion of a nurse. PMID- 6906791 TI - Innovations. 1--microsurgery. A stitch in time. PMID- 6906793 TI - Reith lectures. Power to the people--or professionals? PMID- 6906795 TI - Artificial insemination: aiding and abetting. PMID- 6906796 TI - International cancer nursing conference. 8. Speak in support. PMID- 6906794 TI - Diploma of nursing. Part A. Physiology and psychology. PMID- 6906797 TI - Dependency in agoraphobia. A woman in need. PMID- 6906798 TI - New units for the new NHS. PMID- 6906799 TI - Put it down to principles! Nurses education needs to be rationalized and restructured. PMID- 6906800 TI - Health and safety. 1. Safe as hospitals? The Nurses Action Group. PMID- 6906803 TI - Citizens Advice Bureau. Call me a CAB! PMID- 6906801 TI - Innovations. 2- Mental handicap nursing. A bold experiment. PMID- 6906802 TI - The babymilk controversy. When milk doesn't come first. PMID- 6906804 TI - Mental handicap: the hidden handicap factors. PMID- 6906805 TI - Sexual deviation. Children in danger. PMID- 6906806 TI - Pyloric stenosis. Clearing an obstruction. PMID- 6906807 TI - Business is booming! PMID- 6906808 TI - The progress of 'the process'. PMID- 6906809 TI - Only just a profession. PMID- 6906810 TI - Not a spark of interest! Reactions to fire. PMID- 6906811 TI - Fetoscopy: I spy with my little eye... PMID- 6906812 TI - Diploma of nursing: Part B. Cause and effect: blood clotting. Pseudomonas infections. PMID- 6906813 TI - The art of health visiting. PMID- 6906815 TI - International conference on cancer nursing. 10. Support your team. PMID- 6906814 TI - Nursing research in practice. Practising what is preached. PMID- 6906816 TI - Clay will do it his way... PMID- 6906817 TI - Pain. The last piece in the puzzle. PMID- 6906819 TI - The way they 'manage'. PMID- 6906818 TI - Deep vein thrombosis: tying the knot. PMID- 6906820 TI - Treating patients with allergies by desensitizing them with minute doses of the allergen diluted in saline. PMID- 6906821 TI - Health and safety. 4. Fighting the hidden hazards. The Nurses Action Group. PMID- 6906822 TI - Pressures in nursing. Stresses, strains and smoking. PMID- 6906823 TI - Alcohol counselling service. Think before you drink... PMID- 6906825 TI - Nursing abroad. WHO does what in Europe? PMID- 6906824 TI - Psoriasis. Cells with a silver lining. PMID- 6906826 TI - International cancer nursing conference. 10. Breast restoration. PMID- 6906827 TI - When a nurse is not a nurse... PMID- 6906828 TI - Clinical forum: the eye. PMID- 6906829 TI - Gradual visual loss. PMID- 6906830 TI - Congenital cataracts. PMID- 6906831 TI - Rapid visual loss. PMID- 6906832 TI - Retinal detachment. PMID- 6906835 TI - Conjunctivitis. PMID- 6906834 TI - Retinal dialysis. PMID- 6906833 TI - Central retinal artery occlusion. PMID- 6906836 TI - First, the good news. PMID- 6906837 TI - Royal Preston Hospital: on the map. PMID- 6906840 TI - Superannuation. 2. All round benefits. PMID- 6906839 TI - Health and safety. 6. Dealing with distress. The Nurses Action Group. PMID- 6906838 TI - Living with cancer: for Mara. PMID- 6906841 TI - Innovations. 6. Computer-assisted nursing: chips with everything. PMID- 6906842 TI - Who should decide? PMID- 6906843 TI - Informed consent and the nurse. PMID- 6906844 TI - Invasion of privacy in the hospital. PMID- 6906845 TI - Hiding medical records behind the law. PMID- 6906846 TI - Charting deficiencies and R.N. liability. PMID- 6906847 TI - Nurses' rights: right of free speech. Case in point: Hitt v. No. Broward Hospital Dist. (387 So. 2d 482 - FL). PMID- 6906848 TI - Legal case briefs for nurses. CA: neonatal death: heparin overdose? AZ: errant M.D.: refusal to treat patient. PMID- 6906849 TI - RN's professional acts: hospital accountability. Case in point: South Bend Osteopathic Hosp. v. Phillips (411 N.E. 2d 387 - IND.). PMID- 6906851 TI - Termination of employment: R.N.'s remedies. Case in point: Kurle v. Evangelical Hosp. Assn. (411 N.E. 2d 326 - ILL.). PMID- 6906850 TI - Nursing supervisors and careless R.N.'s. PMID- 6906852 TI - Legal case briefs for nurses. ME: OBS: birth injury; paralysis. GA: "Good Samaritan" nurse injured. PMID- 6906853 TI - Arteriography: nurses, doctors sued - cleared. Case in point: Hirn v. Edgewater Hospital et als (408 N.E. 2d 970 - ILL). PMID- 6906854 TI - [Hemodialysis treatment of chronic renal insufficiency in adults]. PMID- 6906855 TI - [Hemodialysis: the patient and the nurse]. PMID- 6906856 TI - [Caloric and nutritional allowances]. PMID- 6906857 TI - [Nutrition disorders]. PMID- 6906859 TI - [Carpal tunnel syndrome]. PMID- 6906858 TI - [Pericarditis: diagnosis and treatment]. PMID- 6906861 TI - [Utilization of plastic syringes]. PMID- 6906862 TI - [Physiopathology of renal insufficiency]. PMID- 6906860 TI - [Prevention of transfusion accidents]. PMID- 6906864 TI - Toward impeccable IV technique: trouble free IV starts. PMID- 6906863 TI - Sex Q & A: Frank answers to your most delicate patient-counseling questions. PMID- 6906865 TI - Is it right? Protect the MD...or the patient? Nursing's unequivocal answer. PMID- 6906866 TI - Opinion exchange. Right patient, wrong drug: was the nurse to blame? PMID- 6906867 TI - Simple new remedy for the odor of open lesions. PMID- 6906868 TI - Prolapsed disc removal. New surgical approach minimizes post-op pain. PMID- 6906870 TI - Coping: 'Stop driving yourself crazy!'. PMID- 6906869 TI - Collecting synovial fluid and wound drainage cultures. PMID- 6906871 TI - Cancer chemotherapy: those dreaded side effects and what to do about them. Part five. PMID- 6906872 TI - Drug therapy today: latest strategies for post-MI dysrhythmias. PMID- 6906873 TI - Legally speaking: short staffing means increased liability for you. PMID- 6906874 TI - Sound off! Reality shock: are we coping or copping out? PMID- 6906875 TI - B.C. nurses need 'courage to change'. PMID- 6906876 TI - You can do it this way, too. PMID- 6906877 TI - The dollars and sense of health care. Part I. PMID- 6906878 TI - Right to sign: let's clarify the confusion--both emotional and legal--around health care consent by minors. PMID- 6906879 TI - Both parents liable for payment of child's hospitalization. PMID- 6906881 TI - Professional survival: we must redefine expectations to match the amount of our power and the level of our competence. PMID- 6906880 TI - Performance analysis--a how to. PMID- 6906882 TI - A new concept on scheduling for nurses. PMID- 6906883 TI - Managing maladaptive attitudes among nursing personnel. PMID- 6906885 TI - Planning patients' discharge. PMID- 6906884 TI - Quality assurance: an ethical responsibility. PMID- 6906886 TI - Why not chart first? PMID- 6906887 TI - The art and science of supervision: instruments of influence. PMID- 6906888 TI - Nursing--its diversified roles: spotlight on nurse practitioners. PMID- 6906889 TI - Perspectives: an exclusive STAT interview with ANA President Nichols. PMID- 6906890 TI - Nursing education. PMID- 6906892 TI - Power: use it or lose it. PMID- 6906891 TI - Legislative bulletin. PMID- 6906893 TI - The laryngectomized patient: Part II. PMID- 6906895 TI - Urinalysis: examination of the urine sediment. PMID- 6906894 TI - Povidone-iodine gel: a new skin preparation agent. PMID- 6906896 TI - Surgical repair of atresia ani & rectovaginal fistula in a goat. PMID- 6906897 TI - Food-animal regional anesthesia: bovine blocks: intravenous limb block. PMID- 6906898 TI - Cassia obtusfolia (sicklepod) toxicity in a dairy herd. PMID- 6906899 TI - Reduced reproductive potential of Fasciola hepatica surviving in cattle treated with albendazole. PMID- 6906900 TI - Diagnosis of canine wobbler syndrome using myelography (case report). PMID- 6906901 TI - Anatomic orientation for lateral thoracolumbar disc fenestration (a photographic essay). PMID- 6906902 TI - Recurrent esophageal hairballs in a cat (a case report). PMID- 6906903 TI - Nocardiosis in the dog (a clinical case report). PMID- 6906904 TI - Cystic ovary in a dog: a case report. PMID- 6906907 TI - A technique for cosmetic pinioning of adult birds. PMID- 6906906 TI - Cholangiohepatitis in a horse. PMID- 6906908 TI - Watch your language. PMID- 6906905 TI - Data base for polyuria:polydipsia. PMID- 6906909 TI - Tax-wise: how to take the sting out of taxes. PMID- 6906910 TI - Psittacosis on the upswing in California. PMID- 6906911 TI - Legg-Calve-Perthes disease in a lowland gorilla. PMID- 6906912 TI - Azalea poisoning in a Llama: a case report. PMID- 6906913 TI - Necropsy procedures used at the Maryland Department of Agriculture Animal Health Laboratory. PMID- 6906914 TI - Colorimeters and spectrophotometers. PMID- 6906916 TI - Veterinarians and trapping. PMID- 6906917 TI - Pathophysiology and management of medial patellar luxation in the dog. PMID- 6906915 TI - Ethology. The scientific study of animal behavior. PMID- 6906918 TI - Diagnosis of Giardia canis, the elusive parasite. PMID- 6906919 TI - Feline uterine prolapse (a case report). PMID- 6906920 TI - Mesocestoides corti in a dog: a case report. PMID- 6906921 TI - Use of a pacemaker to correct sinus bradycardia in a dog. PMID- 6906922 TI - Outbreak of septicemic listeriosis in a dairy herd. PMID- 6906923 TI - The importance of herd health to swine producers. PMID- 6906924 TI - Food-animal regional anesthesia. Bovine blocks: interdigital nerve block. PMID- 6906925 TI - Infestation of a mare's liver with Gasterophilus intestinalis. PMID- 6906926 TI - Protocol for differential diagnosis of diseases of the equine foot. PMID- 6906927 TI - Data base for weight loss and chronic diarrhea. PMID- 6906928 TI - [Kallikrein-kinin system in macrofocal myocardial infarct during complex treatment]. PMID- 6906930 TI - The who, what, when, why and how of professional negotiations for nurses. PMID- 6906929 TI - Public health nursing faces the challenges in rural health. Part 1. PMID- 6906931 TI - West Virginia legislation for third party reimbursement for nurses. PMID- 6906932 TI - Hospice. PMID- 6906933 TI - Report of the Working Party on general nursing. PMID- 6906935 TI - Message from Ruth B. Bear, R.N., Immediate Past President, VNA. PMID- 6906934 TI - The need for research into nursing in Ireland. PMID- 6906936 TI - Resources for doctoral education in nursing in Virginia and the Carolinas: survey of nurses with graduate degrees. Preliminary report. PMID- 6906937 TI - How much are you worth? PMID- 6906938 TI - Keynote address: strategies for action: policy and politics in health care. PMID- 6906939 TI - The planning of a convention. PMID- 6906941 TI - Practice protection. PMID- 6906940 TI - A prescription for political activation: nursing political networks. PMID- 6906942 TI - Continuing nursing education. Statement of belief - planning & coordinating activities - policies, procedures, criteria for approval. PMID- 6906943 TI - Patient classification systems - an introduction. PMID- 6906944 TI - The A.A.R.N. gives direction: the continuing education document -- so what? PMID- 6906945 TI - A.H.A. "Nursing manpower study of factors in nursing supply and demand" -- November, 1980. PMID- 6906947 TI - "Clonidine in ... withdrawal ...". PMID- 6906946 TI - Eradication of epidemic methicillin-gentamicin-resistant staphylococcus aureus in an intensive care nursery. AB - A methicillin-resistant strain of Staphylococcus aureus (phage type 47,54,75,83A) became epidemic in our 50 bed level III nursery, with a colonization rate of 70 percent and an infection rate of more than 25 percent. This prevalence and the appearance of gentamicin resistance necessitated epidemic control measures. Standard measures included separate housing for infants in whom colonization had occurred and infants in whom it had not, low nurse to patient ratios, and cohorting of all personnel. Use of all antibiotics was curtailed by the requirement of infectious disease consultation. Gentamicin was available only on order of the Director. The colonization rate fell from 55 percent to 25.4 percent, the first-week colonization rate from 31 percent to 0 percent, and the infection rate from 29.3 percent to 15.9 percent over eight weeks. The mean duration of antibiotic therapy decreased from 12.21 to 9.05 days per treated patient; however, the frequency of gentamicin usage and the proportion of gentamicin resistance were unchanged. Nurse to patient ratios were modified to allow increased admissions, but cohorting was continued for 12 weeks until all infants in whom colonization had occurred were discharged. With the elimination of the reservoir, no further colonization occurred and antibiotic resistance did not reappear. Standard infection control measures can eliminate epidemics of multiple antibiotic-resistant Staph. aureus, and control of antibiotic usage may present re-emergence of resistant strains. PMID- 6906949 TI - Staff nurses as clinical teachers. PMID- 6906948 TI - Nursing's leaders: an endangered species? PMID- 6906950 TI - Cisplatin: delivering a safe infusion. PMID- 6906951 TI - Nursing priorities for the 1980's: hospitals and nursing homes. AB - It is clear that the two institutions where nurses play a critical role- hospitals and nursing homes--are experiencing major problems. Patients in these institutions are not receiving the full benefits of the best health care America has to offer. Organized nursing has the opportunity and capacity to resolve these difficulties and in the process improve both patient care and the importance of our profession. The time is right for change. To date, nursing has not taken on this difficult leadership task. I believe we will remain dependent on other professions unless we take on significant responsibilities for resolving the problems facing these two institutions. The GMENAC report on health manpower suggests that out profession should not rely on others for public policy recommendations which will affect our future. Nursing has greater respect and national visibility than ever before. Within this decade, nursing has the potential ability to help resolve the crisis affecting these two institutions. The future of the nation's hospitals, nursing homes, those for whom we care, and of the nursing profession may depend upon how we respond to these two challenges in the years ahead. PMID- 6906952 TI - Discrepancies in estimating blood loss. PMID- 6906953 TI - The patient on radiation therapy. PMID- 6906954 TI - Planning care for the patient receiving external radiation. PMID- 6906956 TI - Choosing daycare. PMID- 6906955 TI - Medication group for psychiatric patients. PMID- 6906957 TI - Authors and publishers: the mutual selection process. AB - Writing a book is a full-time job--a demanding, frustrating, and lonely occupation. Most nurse authors append this task to another full-time job in teaching or practice and, often, to family responsibilities as well. To fulfill all these commitments and emerge physically and mentally healthy requires a special kind of person--one who is organized, disciplined, and tenacious. Yet having written and been published affords a satisfaction unsurpassed by few other experiences. If your careful, informed search for a publisher culminates in a successful book, you will have added an exciting and profitable dimension to your life. PMID- 6906958 TI - Dealing with feelings. Control your thoughts. PMID- 6906960 TI - New antiarrhythmic drugs. PMID- 6906959 TI - New concepts in understanding congestive heart failure. Part 2: How the therapeutic approaches work. PMID- 6906961 TI - Legal restraints on restraint. PMID- 6906962 TI - Life-saving alarm system is brainchild of plant nurse. PMID- 6906963 TI - The nurse: the enabler. PMID- 6906964 TI - Home study feature: pulmonary problems in infants and children. PMID- 6906965 TI - Bronchopulmonary dysplasia. PMID- 6906966 TI - The crises of bronchiolitis. PMID- 6906967 TI - Pneumonia. PMID- 6906968 TI - Foreign body aspiration. PMID- 6906969 TI - How to do segmental postural drainage. PMID- 6906970 TI - Cystic fibrosis. PMID- 6906971 TI - Coin-operated sphygmomanometer. PMID- 6906972 TI - Dealing with feelings: positive self talk. PMID- 6906973 TI - When the patient is the family. PMID- 6906974 TI - Taking charge of change in hospital nursing practice. PMID- 6906975 TI - Organ transplantation: Matching organ donors and recipients. PMID- 6906976 TI - When your client has a weight problem. PMID- 6906978 TI - When your client has a weight problem. Nursing management. PMID- 6906977 TI - When your client has a weight problem. Nursing assessment. PMID- 6906979 TI - Pickwickian syndrome. PMID- 6906980 TI - Teenagers and obesity. PMID- 6906981 TI - Overeaters Anonymous: a self-help group. PMID- 6906982 TI - Gastric partitioning: the latest surgical means to control morbid obesity. PMID- 6906983 TI - Drug data: intravenous admixtures. PMID- 6906984 TI - Dilemmas in practice: to make live or let die. PMID- 6906985 TI - Nurse midwives forced out of practice. PMID- 6906986 TI - Black nursing schools need support, funding. PMID- 6906987 TI - Hospital changes urged to end nursee "shortage". PMID- 6906988 TI - Political action wins friends, influence for nursing. PMID- 6906990 TI - Credentialing center future depends on nursing support. PMID- 6906989 TI - Proposed recommended practices for OR wearing apparel. PMID- 6906991 TI - Methods of data collection. PMID- 6906992 TI - Are your fears keeping you from being assertive? PMID- 6906993 TI - What goes into an examination? A good question. PMID- 6906994 TI - Public has confidence in surgical care. PMID- 6906995 TI - Adult scoliosis: a personal experience. PMID- 6906996 TI - Preoperative fluid balance assessment. PMID- 6907000 TI - All nurses can be involved in teaching patient and family. PMID- 6906998 TI - Mehaffy discusses technicians at ACS. PMID- 6906999 TI - Surgeons summarize progress. PMID- 6906997 TI - Mediastinoscopy in bronchogenic carcinoma. PMID- 6907001 TI - The patient as an adult learner. PMID- 6907002 TI - The hypophysectomy patient in the OR. PMID- 6907004 TI - Proposed recommended practices for documentation of perioperative nursing care. PMID- 6907003 TI - Nursing care for hypophysectomy. PMID- 6907005 TI - An OR nurse reports from the "mainstream' of patient care. PMID- 6907006 TI - Data analysis and statistics. PMID- 6907007 TI - OR nursing in correctional facilities. PMID- 6907008 TI - Finding an OR job abroad. PMID- 6907009 TI - Nursing shortage less severe in ORs. PMID- 6907010 TI - Spinal cord injury: impact on clients' significant others. PMID- 6907012 TI - "A" formula for professional nursing care. PMID- 6907011 TI - Continuity of care for spinal cord injury--a reality. PMID- 6907013 TI - Life cycle; simulation game for understanding senior citizens. PMID- 6907014 TI - Children: the right to removal and other rights. PMID- 6907015 TI - Peptide elongation in rat kidney after cadmium administration. AB - Rats received two injections (each 2.6 mg/kg body wt.) of CdCl2, and the kidneys were removed 24 h later. Postmicrosomal supernatant fractions of the homogenized kidneys were used as a source of elongation factors 1 and 2 in assays for [14C]phenylalanyl-tRNA binding to ribosomes and for peptide-bond synthesis. After purification of these preparations by precipitation with (NH4)2SO4 and gel filtration on Sephadex G-200 and G-100, elongation factor 1 activity was significantly increased. A significant increase in the activity of purified elongation factor 2 was also found. The results are discussed in relation to the reported effects of CdCl2 and of HgCl2 on renal tissue. PMID- 6907016 TI - Affinity-chromatographic purification of human alpha 2-antiplasmin. AB - A new simple and efficient purification method for alpha 2-antiplasmin is described that is based on the interaction between alpha 2-antiplasmin and a fragment from elastase-digested plasminogen constituting the three N-terminal triple-loop structures in the plasmin A-chain (LBSI). After a single-step adsorption of the alpha 2-antiplasmin from plasminogen-depleted plasma to LBSI Sepharose and elution with 6-aminohexanoic acid, an 80-90% pure preparation with a yield of 50-60% is obtained. The major impurity is fibrinogen, which can easily be removed by gel filtration, and, as a result, a homogeneous fully active alpha 2-antiplasmin preparation is obtained that has the same properties as previously described for alpha 2-antiplasmin. Evidence is put forward that a form of alpha 2 antiplasmin with less affinity for the lysine-binding sites in plasminogen may exist, even in unfractionated plasma. PMID- 6907017 TI - Stimulation of polypeptide synthesis by spermidine at the level of initiation in rabbit reticulocyte and wheat germ cell-free systems. PMID- 6907019 TI - Transfer ribonucleic acid genes in the chloroplast deoxyribonucleic acid of pea leaves. AB - The saturation hybridization between pea ctDNA and 125I-labeled pea ct-tRNAs has shown that 1.2% of the peak ctDNA codes for tRNA genes. The observed level of hybridization has been found to result from specific base pairings between ctDNA and ct-RNA as shown by competition hybridization experiments and thermal stability studies on DNA-tRNA hybrids. The level of hybridization obtained in this study amounts to the presence of approximately 40 tRNA genes in pea ctDNA. The tRNAs from the cytoplasm of the pea leaves, Escherichia coli, yeast, and calf thymus did not compete with the pea ct-tRNAs for the common base sequences in pea ctDNA. The presence of 17 aminoacyl-tRNA synthetases and their corresponding tRNAs was demonstrated in chloroplast. The acylation of ct-tRNAs proceeds with the same rate whether the partially purified tRNA synthetases from chloroplasts of E. coli are used. The aminoacylation of the three amino acids glutamic acid, glutamine, and cysteine proceeded very slowly in chloroplasts. The individually labeled aminoacyl-tRNAs hybridized with pea ctDNA. The hybridization follows true saturation rates, and the melting profiles of aminoacyl-tRNA-ctDNA indicate the formation of specific base pairs between the ctDNA and tRNA. Seventeen aminoacyl tRNA genes have been identified in the pea ctDNA. PMID- 6907020 TI - The use of clonidine in detoxification from opiates. AB - Use of clonidine hydrochloride in detoxification from opiates has demonstrated that this substance can rapidly suppress the signs and symptoms associated with opiate withdrawal. Clonidine hydrochloride, an alpha-adrenergic agonist, is a non opiate substance. Studies to date indicate that clonidine is useful for withdrawal from methadone maintenance, where it can help in detoxifying the patient in less than 14 days (instead of the usual three to six months) with a high rate of success in achieving zero dosage. The results of a clinical investigation of clonidine are presented and discussed in this paper. It has been shown to suppress signs and symptoms of opiate withdrawal in patients taking up to 75 mg of methadone daily. Shorter-acting narcotics may be withdrawn in less than a week. To prevent relapse, post-detoxification counselling and the use of the narcotic antagonist, naltrexone, are recommended. PMID- 6907018 TI - Lipoprotein-elastin interactions in human aorta fibrous plaque lesions. AB - The nature of lipoprotein and elastin associated with hyaluronate in human atherosclerotic plaque tissue was studied by digesting the tissues with elastase. The elastase-solubilized lipoprotein-hyaluronate complexes, isolated by Bio-Gel A 50m column chromatography, contained 7.8 mg calcium/100 mg protein. The Sephadex G-200 chromatography of delipidated complexes yielded high (fraction I) and low (fraction II) molecular weight protein fractions. Dialysis of the complexes against 0.01% EDTA resulted in removal of fraction II. Fraction I reacted immunologically against antihuman LDL, and its amino acid composition resembled that of human apoB. Fraction II contained 5 peptide fragment and had high levels of nonpolar amino acids that are characteristic of elastin. However, these peptides also contained high levels of polar amino acids, thus resembling the plaque elastin. These findings suggest that certain regions of plaque elastin may have affinity for apoB containing lipoproteins and calcium. PMID- 6907021 TI - Identifying drug-dependent persons in a survey: a note on methodological issues. AB - A survey of 2,064 male persons in a rural area revealed that 423 (20.5 per cent) expressed craving for one or more abused substances. Close relationships were found between self-expressed craving and daily use of a drug. These data also suggest that in a large-scale survey, self-expressed craving and frequency of drug use could be used for fairly reliable estimates of the state of dependence on a drug. PMID- 6907022 TI - A methodology for intensive case-finding and monitoring of drug use in Mexican community. AB - An intensive case-finding model of drug use is presented with respect to its advantages and limitations. Two approaches were used: (a) direct, in which the questions concerning drug use were asked openly by the field-workers, and (b) indirect, where the field-workers obtained information about drug use from general conversation with interviewees. The indirect approach was found to be very useful in contacting new drug users and in assessing the psycho-social context of drug use. This research suggests that the intensive case-finding method is suitable for a community where the majority of drug users form cohesive groups, while it was found to be less effective for the study of isolated cases. PMID- 6907023 TI - Urine drug testing survey and characteristics of populations of seven Los Angeles County methadone maintenance clinics. AB - One thousand urine samples from each of the seven Los Angeles County methadone maintenance clinics were examined for presence of drugs of abuse. The clinic populations were also concurrently studied with regard to various social factors. Significant variations which have been found among the clinics in both population characteristics and drugs detected in urine samples are discussed in the paper. PMID- 6907024 TI - Illicitly imported Cannabis products: some physical and chemical features indicative of their origin. AB - Samples taken from seizures of illicitly imported cannabis and cannabis resin of known geographical origin have been examined by thin-layer chromatography. The chromatographic characteristics were considered in conjunction with the gross physical appearance of the materials and it was found possible to discriminate between samples of different origin. Thus by carrying out thin-layer chromatography and a visual inspection on a sample of unknown provenance, an opinion as to its geographical origin can be offered. Extensive use is made of a reference collection of samples. PMID- 6907026 TI - Recovery of thebaine and cryptopine from Indian opium. AB - The thebaine content of the opium collected in the Madhya Pradesh region of India has been estimated and reported to range from 1.5 to 2.0 per cent. A technological process for the recovery of thebaine from the mother liquor remaining after the separation of natural codeine in the Government Opium and Alkaloid Works, Neemuch, has been developed in the laboratory and stepped up to an industrial scale. A method for the recovery to thebaine from the waste slaked lime residues obtained from crude alkaloid cake mother liquor in the Government Opium and Alkaloid Works at Ghazipur has been worked out and the technical details of the process described. The recovery of thebaine would help to increase the production of codeine, and thebaine can also be used as a raw material for the manufacture of other drugs. Cryptopine has also been recovered from the mother liquor after the separation of thebaine. PMID- 6907027 TI - Effect of vanadate on rat myometrium plasma membrane enzyme activities. AB - Vanadate inhibited K+-activated and K+-activated ouabain-sensitive p-nitrophenyl phosphatases of rat myometrium at nanomolar concentrations. The vanadate concentrations required for 50% inhibition were 220 +/- 30 nM for the K+ activated component of the enzyme and 200 +/- 30 nM for the K+-activated ouabain sensitive component. Micromolar concentrations of vanadate inhibited acid and alkaline p-nitrophenyl phosphatases. ATP-dependent Ca uptake by the plasma membrane vesicles was not inhibited by 10nM - 1 mM vanadate. Mg2+-ATPase was also not affected. Thus K+-activated and K+-activated ouabain-sensitive p-nitrophenyl phosphatase activities of the plasma membrane were most sensitive to inhibition by vanadate. Preliminary experiments demonstrated that similar to ouabain, vanadate inhibited potassium-induced abolition of spontaneous contractile activity of isolated rat myometrium in K-free Krebs. This effect of vanadate is consistent with vanadate inhibition of K+-activated ouabain-sensitive p nitrophenyl phosphatase. PMID- 6907025 TI - The role of testosterone in the development of experimental alcoholism. AB - The hormonal effects of testosterone, progesterone and extradiol on voluntary preference of ethanol were investigated in experiments carried out on castrated male albino rats. It was observed that testosterone stimulated the development of ethanol preference, while the effects of progesterone and estradiol were significantly slower and less intensive. It was also observed that the androgenic action of testosterone was more important than its anabolic action in stimulating ethanol preference. PMID- 6907029 TI - The Ontario experiment. PMID- 6907030 TI - A new lifestyle in a new land. PMID- 6907028 TI - The paradoxical nature of helpless behaviour: control through helplessness. PMID- 6907031 TI - A "professional" approach to helping immigrants and refugees. PMID- 6907032 TI - A model for cultural assessment of the new immigrant. PMID- 6907033 TI - The East Indian family in Canada. PMID- 6907034 TI - The adolescent immigrant. PMID- 6907035 TI - Self-medication. PMID- 6907036 TI - Let's cool the shop talk. PMID- 6907037 TI - New goals for oral hygiene. PMID- 6907038 TI - Women as health care consumers. PMID- 6907040 TI - When regression becomes a problem. PMID- 6907039 TI - Community nursing in Quebec. PMID- 6907041 TI - Baby talk. PMID- 6907042 TI - Nurses and politics. PMID- 6907043 TI - For nurses only. Nursing management. PMID- 6907044 TI - The silent majority. PMID- 6907045 TI - We can weekend: a program for cancer families. PMID- 6907046 TI - Oral hygiene measures for patients with cancer. III. PMID- 6907048 TI - Oncology nursing conflict: a case presentation of holistic care and the family in crisis. PMID- 6907047 TI - Pancreatic insufficiency in the person with cancer. PMID- 6907050 TI - Programmed instruction: cancer care. Leukemia: a hematology review. PMID- 6907049 TI - Cancer nursing and the law. The duty to advise of minority opinions. PMID- 6907051 TI - Development of a self-care teaching program for postoperative head and neck patients. PMID- 6907054 TI - Sexuality and the cancer patient. PMID- 6907053 TI - Use of the heparin lock on an outpatient basis. PMID- 6907052 TI - Oncology grand rounds for nurses: the need for case-oriented continuing education programs in cancer nursing. PMID- 6907055 TI - Cancer nursing and the law. Emotional injuries. PMID- 6907056 TI - Pharmaceutics: mechlorethamine (nitrogen mustard). PMID- 6907057 TI - Programmed instruction: cancer care. Leukemia: the leukemia process. PMID- 6907058 TI - Beyond the hospital ... who cares? PMID- 6907059 TI - Early exercise testing after myocardial infarction. PMID- 6907060 TI - [Effect of ionizing radiation on enzymes. II. The effects of gamma rays on chymotrypsin activity in pancreatin]. PMID- 6907061 TI - Centrifugal analysis for plasma kallikrein activity, with use of the chromogenic substrate S-2302. AB - The amidolytic activity of activated kallikrein in plasma can be measured by use of the chromogenic substrate, S-2302 (H-D-Pro-Phe-Arg-pNA). Plasma prekallikrein was activated to kallikrein by exposure to 50 mg/L dextran sulfate in acetone/water (35/65 by vol) at 0 degrees C for 15 min. The acetone slows anti kallikrein activity and increases the kallikrein activity by 30%. The 37 degrees C reaction mixture contained 0.54 mmol of S-2302 substrate per liter of Tris buffer (pH 7.5 at 37 degrees C). We monitored the change in absorbance at 405 nm for 60 s. The specificity of the substrate for kallikrein was demonstrated by using plasma deficient in prekallikrein (Fletcher trait) diluted with pooled normal human plasma. We recommend collecting blood specimens with sodium citrate as the anticoagulant and with use of a double-syringe technique and all-plastic containers. Plasma kallikrein activity with Chromozym-PK (Bz-Pro-Phe-Arg-pNA) as substrate (y-axis) compared with S-2302 as substrate (x-axis) gave the relation: y = 0.28x + 0.82 (r = 0.94). Day-to-day analytical variation was 2.4% for a pooled plasma with a mean value of 85.9 mukat/L. The mean (and 2 SD) for 50 healthy adults was 86.4 (32.4) mukat/L. PMID- 6907062 TI - Renal hemodynamic changes during long-term antihypertensive therapy. AB - Studies of renal hemodynamics were carried out in 84 patients with essential hypertension during long-term antihypertensive therapy with a number of drugs. Renal perfusion was maintained or enhanced despite a fall in mean arterial pressure during therapy with hydrochlorothiazide, furosemide, clonidine, prazosin, and the combination of guanabenz and hydrochlorothiazide. Renal perfusion deteriorated during long-term treatment with propranolol. Renal hemodynamics may be enhanced, maintained, or adversely influenced depending on the choice of antihypertensive agent. PMID- 6907063 TI - What does the health visitor do? PMID- 6907065 TI - Special foods for special babies. PMID- 6907064 TI - A 24-hour HV service. PMID- 6907066 TI - A resource - the dietitian. PMID- 6907067 TI - Another world. PMID- 6907068 TI - Conflict. PMID- 6907069 TI - Psychosocial update! Resolution for 1981! A healthful year through self-care. PMID- 6907070 TI - Toxic shock syndrome: an update. PMID- 6907071 TI - New sunlamp standards and photosensitivity. FDA drug bulletin - July 1980. PMID- 6907072 TI - Neonatal necrotizing enterocolitis. PMID- 6907073 TI - Hyperbaric oxygen therapy. PMID- 6907074 TI - Nursing management of the head injured patient. PMID- 6907075 TI - Infection control update! Chlamydia. PMID- 6907076 TI - Patient education update! Often asked questions about patient health education. PMID- 6907077 TI - Cancer chemotherapy. PMID- 6907078 TI - A comparison of the myocardial depressant effects of several aminoglycoside antibiotics. AB - The myocardial depressant action of aminoglycosides has been known for a number of years but there was no available data on newer derivatives. We have thus studied the contractile responses of isolated guinea pig left atria to increasing concentrations of gentamicin, tobramycin, lividomycin and amikacin (0.02, 0.04, 0.08, 0.13, 0.17 and 0.22 mM). Our results are consistent with those of previous workers and show that newer aminoglycosides do exert a similar depressant action. As gentamicin and tobramycin are more depressant than lividomycin, then amikacin at similar concentrations, no clear-cut difference was obtained when respecting a relative range of concentrations mimicking that of clinical situations. However, these depressant effects were attained using concentrations far exceeding those reached in man. PMID- 6907080 TI - Ultrastructural organization of the alveolar-capillary unit. AB - As a result of its special position in the circulatory system the lung can screen and monitor the composition of the blood which comes from and is returned to all the tissues. This function, together with the exchange of gases, takes place at the level of the alveolar-capillary unit. The cellular components of the unit are: the epithelium, lining the air spaces, and the endothelium, facing the blood compartment. The epithelium is composed of two types of cells: type I--broad, squamous, highly branched cells occupying approximately 97% of the total alveolar surface; these cells seem to be involved mostly in exchange of gases; and type II -cuboidal cells containing characteristic osmiophilic lamellar bodies in their cytoplasm. The epithelial cells are connected to one another by tight junctions. A thin layer of a surface-active material--the surfactant--covers the epithelium toward the air space, where its role is to lower the surface tension. Surfactant is a mixture of lipids (approximately 75%) and proteins; dipalmitoyl phosphatidylcholine is the major lipid component and is synthesized and secreted by type II epithelial cells. The endothelium is of continuous type and has a large population of plasmalemmal vesicles; the cells are linked together by tight junctions. Morphometric studies indicate that in humans the capillary surface area is approximately 120 m2 and the alveolar surface area is approximately 140 m2. Some of the metabolic functions ascribed to the lung have been localized to cellular components. Phospholipids needed for the constantly renewed surfactant are synthesized in type II epithelial cells. Angiotensin-converting enzyme is associated with the endothelial cell membrane and vesicles opening to the blood front. There are indications that pulmonary cells also intervene in the metabolism of circulating vasoactive substances which during their passage through the lung can be activated (angiotensin I), inactivated (bradykinin) or removed from the circulation (5-hydroxytryptamine). The lung is a metabolically active organ where the anabolism and catabolism of pharmacologically active substances and the synthesis of lipids take place and a proper balance for blood homeostasis is maintained. PMID- 6907079 TI - Inactivation of monoamines by the lung. AB - Inactivation of monoamines was the first pharmacokinetic property of lung to be identified. For some amines inactivation in perfused lung but not in liver is limited by uptake. Inactivation of beta-phenylethylamine in lung is limited not by uptake but by the activity of intracellular monoamine oxidase. The uptake of this amine is like that of basic drugs such as amphetamine and propranolol. Changes in the external environment of the lung (exposure in vivo to gaseous anaesthetics or to high concentrations of oxygen, greater than 95%) change amine inactivation processes in lung. The oestrous cycle and administration of ovarian steroids also affect the inactivation of 5-hydroxytryptamine and phenylethylamine. Monoamine oxidase activity in lung homogenates is highest at met- and lowest at pro-oestrus for both substrates. However, in perfused lung, inactivation is better correlated with variations in uptake. Therefore the main effect of the oestrous cycle is on uptake rather than on enzymic activity. Uptake processes are thus crucial determinants of monoamine activation in lung and the pharmacokinetic properties of lung are capable of responding to changes in its internal or external environment. PMID- 6907081 TI - Regulation of pulmonary arachidonic acid metabolism by anti-inflammatory steroids. AB - Enzymes in cells from many tissues including the lung metabolize arachidonic acid to a variety of highly active local hormones such as prostaglandins and 'slow reacting substances'. Many of these play a part in the inflammatory response which follows injury or trauma or, in the case of slow-reacting substance, asthmatic bronchoconstriction. Both non-steroidal and steroidal anti-inflammatory drugs inhibit the formation of some or all of these products. The non-steroidal drugs block prostaglandin formation but not the formation of products such as slow-reacting substances. The steroids block the formation of all products. Their mechanism of action, investigated in the guinea-pig perfused lung, involved inhibition of arachidonic acid liberation, probably by suppression of phospholipase activity. To achieve this steroids must first bind to receptors in lung tissue and initiate de novo RNA and protein synthesis. This culminates in the synthesis or secretion by some cells in the lung of a polypeptide of mol.wt. 10 000-15 000 with potent anti-phospholipase properties. The generation of this factor could partly explain why steroids are so effective in the treatment of many types of inflammatory disease, and in particular why they are so efficacious against asthma. PMID- 6907082 TI - Hormonal influences during fetal lung development. AB - Maturation of the fetal lung is accelerated by in utero treatment with corticosteroids and thyroid hormones. Other agents such as catecholamines, thyrotropin-releasing hormone, oestradiol, heroin and cyclic AMP also influence pulmonary phospholipid metabolism. Glucocorticoids cause precocious development of both lung morphology and the surfactant system in type II cells, resulting in more stable lungs with increased air space. The properties of glucocorticoid action are consistent with enzyme induction mediated by interaction of steroid with cytoplasmic glucocorticoid receptors. Receptors are present in lung of many species, including the human fetus, and in both pulmonary fibroblasts and type II cells. Corticosteroid therapy of women in premature labour is currently used to reduce the incidence of infant respiratory distress syndrome (RDS). Treatment of the mother with 12 mg betamethasone causes an approximately four-fold maximal increase in unbound glucocorticoid activity in fetal plasma which is calculated to cause 80% nuclear occupancy by receptor-steroid complex. It is likely that endogenous corticoids influence normal lung development; possible sources of cortisol include the fetal adrenal, maternal adrenal, and conversion of cortisone to cortisol by amniotic membranes and lung fibroblasts. Thyroid hormones have effects similar to corticosteroids, but appear to influence different biochemical steps. Synthetic analogues of triiodothyronine (T3) are available which readily cross the placenta, in contrast to T3 and thyroxine, and accelerate surfactant synthesis and release. Thyroid hormones probably act through nuclear receptors which are present in lung of both animals and the human. Thyroid treatment in utero also appears to accelerate lung maturation and prevent RDS in premature infants. PMID- 6907083 TI - Hypoxia and pulmonary vascular endothelium. AB - The steady development of pulmonary hypertension in the rat between Days 1 and 14 of exposure to hypoxia is based largely on structural remodelling of the pulmonary arterial circulation. The changes induced by hypobaric hypoxia (380 Torr; PaO2 of 40 mmHg) are different in the pre-acinar muscular arteries from the intra-acinar (alveolar wall) arteries, including the effect on the endothelial cell. Quantitative analysis of normal lungs has revealed structural features peculiar to the pulmonary microcirculation. The precapillary arterial unit that lies within the alveolar region includes (i) a non-muscular region and (ii) a partially muscular region as well as (iii) a muscular region. The endothelial cells in these segments or 'compartments' appear different from each other in the normal animal and behave differently in disease. In the various segments the endothelial cell has different neighbours and there are differences in its boundary markers (the basement membrane and elastic lamina). In the normal precapillary arterial unit the neighbour may be a pericyte, intermediate cell or smooth muscle cell. The pericyte and intermediate cell are precursor smooth muscle cells that under the influence of hypoxia develop into mature muscle. PMID- 6907084 TI - Methods for the study of lung metabolism. AB - The recognition of the non-respiratory functions of the lung has led to an increased interest in pulmonary metabolism. The practical methods used to study metabolism in other tissues have all been applied to the investigation of lung metabolism. Methods fall into two groups: those used in vivo and those used in vitro after disrupting the organ or isolating it from other tissues and perfusing its circulation. Some of the methods used in vitro disturb the tissue environment in such a way as to introduce experimental artifacts which make the interpretation of results difficult. There are advantages to the use of the isolated perfused organ technique which, although it has been established for many years, has recently been improved. This method lends itself particularly well to studies of the intermediary metabolism and uptake of drugs by lung tissue. These improvements are described and the application to pulmonary drug uptake is illustrated by reference to the drug mexiletine. The relative advantages of the various methods and their applications are discussed. PMID- 6907085 TI - Copper in fetal and neonatal development. AB - The essentially of copper for normal fetal and neonatal development has been well documented, although copper metabolism during this period is poorly understood. The dietary requirement for copper is influenced by genetic background. The neurological phenotypic characteristics of the mutant gene quaking (qk) in mice resemble in part those of copper-deficient animals. Supplementation of the maternal diet with copper during pregnancy and lactation, or during lactation alone, greatly reduced the frequency of tremors characteristic of these mutants, and brought the otherwise low copper concentrations in the brain to normal. Prenatal copper supplementation of crinkled (cr) mice increased neonatal survival and produced nearly normal development of skin and hair. Non-supplemented cr/cr mice showed anaemia at 21 days of age which disappeared later. Similarly, copper concentration in liver and hair was low in young but normal in old cr/cr mice. However, activity of copper--zinc-superoxide dismutase (Cu-ZnSOD) remained low even at 60 days of age. Copper supplementation brought both SOD activity and copper concentration of liver and hair to normal. The errors in copper metabolism produced by qk and cr appear to be expressed at different periods of development. The hypothesis that there are rapid changes in the metabolism of copper is supported by the observation that molecular distribution of copper in rat intestine changes drastically during the neonatal period. PMID- 6907086 TI - Absorption, transport and distribution of copper. AB - This paper deals with the way animals regulate the supply of copper to sites within the body where the metal exercises its functions. Homeostasis is maintained by the control of both absorption and excretion of the metal, although the efficiency with which this balanced is achieved varies between species. These processes are influenced by dietary intake of copper and they also depend on genetic factors, age, dietary composition and the physiological state of the animal. Some of these effects are described, with emphasis on the possible mechanism of absorption of the metal. The distribution of copper after its absorption from the intestine and, in particular, its uptake by the liver and kidneys are also discussed. Much of the copper removed by these organs is incorporated into, and may induce synthesis of, metallothionein. The precise role of this protein in copper metabolism is still, however, a matter of conjecture. The subsequent binding of hepatic copper to metalloenzymes, its excretion in bile and its incorporation into lysosomes during copper overload are also considered. PMID- 6907087 TI - Copper and neurological function. AB - The role of copper in maintaining normal neurological function has been examined in animals copper-deficient by dietary means, and in the genetic disorders of copper homeostasis -- Menkes' kinky-hair disease in humans and the mottled (Mo) mutants in the mouse. With the exception of the disorder in Mo mice, reduced myelination is a constant feature of these copper diseases but there is otherwise a lack of conformity in the structural defects produced in different species. Dietary copper-deficient animals show a reduction in noradrenaline and dopamine concentrations, together with a depressed tyrosine 3-monooxygenase activity (EC 1.14.16.2). Noradrenaline concentrations are also reduced in brain tissue of Mo mice and this reduction is associated with a decrease in the vivo activity of the copper metalloenzyme, dopamine beta-monooxygenase (EC 1.14.17.1). Many tissues contain potent inhibitors of dopamine beta-monooxygenase activity, and assays of this enzyme have utilized cupric ions to inactivate these inhibitors. The elevated in vitro activities of dopamine beta-monooxygenase obtained for both Mo brain and adrenal tissue may therefore reflect either a reduced inactivation of these endogenous inhibitors in the intact animal or the activation in vitro of apoenzyme. Concentrations of dopamine and tyrosine 3-monooxygenase are unchanged in Mo mice. The reduction in dopamine and tyrosine 3-monooxygenase activity in dietary copper-deficient animals may therefore reflect neuronal loss rather than reduced catalytic activity of the catecholamine biosynthetic pathway. The possible effects of depressed activities of cytochrome c oxidase (EC 1.9.3.1) and superoxide dismutase (EC 1.15.1.1) in the development of neurological dysfunction are also discussed, and attention is drawn to the possible significance of the elevated uptake of neutral amino acids, especially tyrosine and tryptophan, by Mo brain tissue. PMID- 6907088 TI - Copper and hepatic function. AB - When hepatic excretion of copper into bile is impaired, the amount of copper in the liver increases. This happens in extrahepatic cholestasis, primary biliary cirrhosis and in two inherited diseases of copper disease. By six months of age the homozygously affected Bedlington terrier has already begun to accumulate copper in its liver. The trend continues, peaking at the age of five to eight years, when hepatic copper may exceed 10 000 microgram/g dry weight (normal 90- 400 microgram/g in livers from mongrels). Despite these concentrations, which are several times higher than those found in any human disease, there is remarkable little evidence of hepatic inflammation or fibrosis in younger Bedlington terriers. The copper is condensed in lysosomes and is identified by X-ray emission spectroscopy. Hepatic cirrhosis eventually develops and death is often associated with ascites and jaundice. Despite characteristic histological differences between the livers in Wilson's disease and in the Bedlington disease, there is a striking general resemblance between the two conditions. PMID- 6907089 TI - Therapeutic uses of copper-chelating agents. AB - Equilibrium analysis of a model system for the in vivo reactions between penicillamine and copper (I), the penicillamine--glutathione--Cu(I) system, indicates that in a certain concentration range the therapeutic use of penicillamine will not disturb the normal Cu(I) metabolism. The equilibrium data required for this analysis were obtained by e.m.f. titrations on the Cu(I) glutathione (H3A) and on the Cu(I)-penicillamine (H2A) systems at 25 degree C, in 0.5 M NaClO4 medium, using glass and copper amalgam electrodes; the data were analysed first by various graphical methods and then by a general least-squares computer program. The results show that mononuclear Cu(I) species, Cu(HA)2, from in both systems; in addition, the polynuclear Cu5A4(3-) species forms in the penicillamine system and the mononuclear CuHA- species might form in the glutathione system. The results are discussed in relation to the therapeutic use of penicillamine. PMID- 6907090 TI - Metabolic interactions of copper with other trace elements. AB - Metabolic interactions between copper and other trace elements influence not only the susceptibility of animals and humans to deficiency or toxicity of copper but also the biochemical and pathological consequences of these states. Antagonistic trace elements affect the utilization of copper by reducing its solubility within the intestinal lumen, by competing with copper during its absorption or transport, or by modifying its distribution between receptors in body tissues. The derangement of iron-dependent functions during the development of copper deficiency provides a further example of such interactions which, in this instance, arise from the involvement of copper in processes that apparently regulate the flux of iron between plasma and cellular pools. This paper deals with recent studies of the mechanisms of the interactions between copper and zinc, cadmium molybdenum and iron. PMID- 6907091 TI - Copper proteins and copper enzymes. AB - The copper proteins that function in homeostasis, electron transport, dioxygen transport and oxidation are discussed. Particular emphasis is placed on the role of the ligands, their type and disposition which, in conjunction with other residues in the active site, determine the role of the copper ion. It is proposed that copper proteins can be considered in four groups. Those in Group I contain a single copper ion in an approximately tetrahedral environment with nitrogen and sulphur-containing ligands. Group II proteins have a single copper ion in a square-planar-like arrangement. Group III proteins have two copper ions in close proximity. Group IV consists of multi-copper proteins, composed of sites representative of the other three groups. PMID- 6907092 TI - Caeruloplasmin: a multi-functional metalloprotein of vertebrate plasma. AB - Ceruloplasmin is a blue copper protein found in the alpha 2-globulin fraction of vertebrate plasma. It is a single-chain glycoprotein of molecular weight 132 000. It contains six copper atoms per molecule, comprising three or possibly four different types of copper. Its many functions may be related to the heterogeneous nature of these six copper atoms and to the various catalytic activities which they provide. Caeruloplasmin resembles albumin and transferrin in that all three serum proteins are regarded primarily as transport proteins. However, each has numerous other action as important as this transport function. Caeruloplasmin directly mobilizes iron into the serum and provides the major molecular link between copper and iron metabolism; it is the most prominent serum antioxidant, preventing deleterious oxidation of polyenoic acids and other substrates; it scavenges superoxide radicals; it serves as an acute-phase reactant (an endogenous modulator) of the inflammatory response; finally, caeruloplasmin may regulate the serum concentration of the biogenic amines, adrenaline (epinephrine) and serotonin (5-HT). PMID- 6907093 TI - Sickle cell disease. PMID- 6907094 TI - [Holistic health in nursing: 34th anniversary of the foundation of National Institute of Nutrition]. PMID- 6907096 TI - [Holistic health at the physician-nurse level]. PMID- 6907095 TI - [Holistic health: final message]. PMID- 6907097 TI - [Organization of nursing in rural communities]. PMID- 6907098 TI - [Evolution of the transformation processes of the ethical legal nursing principles and standards in the last decade]. PMID- 6907099 TI - Effects of vanadate on mechanical responses and Na-K pump in vascular smooth muscle. AB - The effects of vanadate on tension and on the Na-K pump in isolated guinea-pig aorta were investigated. Vanadates (NH4VO3 or Na3VO4 . nH2O) (10(-3) M) produced a sustained contraction (about 0.5 g) which was not influenced by phentolamine (10(-6) M). In the absence of external Ca, vanadate and norepinephrine (2 x 10( 6) M) induced a small contraction, although high K (45.4 mM) did not. In a Ca depleted, high K (142.2 mM) solution, vanadate and norepinephrine still caused muscle contraction. D600 (10(-6) M) slightly inhibited the contractions induced by vanadate and norepinephrine, while this agent completely inhibited the contraction induced by high K. Sodium nitroprusside (10(-5) M) strongly inhibited the contractions induced by vanadate and norepinephrine but not the contraction induced by high K. Vanadate produced a contraction in K-free solution with ouabain (10(-4) M). The tissue K content did not change during a 2 h treatment of the muscle with vanadate. Reaccumulation of K following a 3 h treatment of the muscle with K-free solution was inhibited by ouabain but not by vanadate. These results indicate a similarity between the contractions induced by vanadate and by norepinephrine and suggest that the vanadate-induced contraction is not due to an inhibition of the Na-K pump. PMID- 6907100 TI - [Industrial hygiene and radiation safety for x-ray laboratory worker]. PMID- 6907101 TI - [Goals and tasks of the All-Union "Ready for Work and for the Defense of the USSR" program complex]. PMID- 6907102 TI - [Peptic ulcer of the stomach and duodenum]. PMID- 6907103 TI - [Use of mineral waters and therapeutic nutrition in stomach diseases]. PMID- 6907104 TI - [Therapeutic and dietary importance of milk and fermented dairy products in digestive organ diseases]. PMID- 6907105 TI - [Raise the level of health protection for the population!]. PMID- 6907106 TI - [Dysfunctional uterine hemorrhages]. PMID- 6907107 TI - [Modern propaganda of medical and hygienic knowledge]. PMID- 6907108 TI - [Fluorographic examinations of the population]. PMID- 6907109 TI - [Work of the provincial council of feldshers and midwives]. PMID- 6907110 TI - [Prevention of acute otitis externa in miners]. PMID- 6907111 TI - [Physiological method and intrauterine devices for contraception]. PMID- 6907113 TI - [Soviet exhibit at the 2d International Specialized Exposition "Public Health 80"]. PMID- 6907112 TI - [Use of an electric suction pump converted from the Shmel' home electric vacuum cleaner]. PMID- 6907114 TI - [Arthrosis deformans]. PMID- 6907115 TI - [Fractures in the elderly]. PMID- 6907116 TI - [Throat lesion in blood diseases]. PMID- 6907117 TI - [Clinical evaluation of biochemical analyses]. PMID- 6907118 TI - [Clinical evaluation of blood analyses]. PMID- 6907119 TI - [Work organization problems of the health centers in industrial enterprises]. PMID- 6907120 TI - [Health education in auxiliary schools]. PMID- 6907122 TI - [Clinical aspects, diagnosis, treatment and prevention of climacteric cardiopathy]. PMID- 6907121 TI - [Ways to increase hygiene teaching effectiveness]. PMID- 6907123 TI - [Clinical aspects, diagnosis and treatment of cancer of the corpus uteri]. PMID- 6907124 TI - [Antialcohol propaganda]. PMID- 6907125 TI - [Work in a psychoneurological isolation ward]. PMID- 6907126 TI - [Feeding infants in the 1st year of life]. PMID- 6907127 TI - [Congenital adrenogenital syndrome]. PMID- 6907129 TI - [Nursing approach of complications in intravenous therapy]. PMID- 6907128 TI - [The status of women and children in Denmark]. PMID- 6907130 TI - [A novel treatment of decubitus]. PMID- 6907131 TI - [The nurse at the cross roads of the health professions and the hospital authorities]. PMID- 6907132 TI - [The 7th pandemic: cholera. A review in 25 points]. PMID- 6907133 TI - [From "nursing care" to "professional nursing". Observations on (systematic) nursing functions]. PMID- 6907134 TI - [Study of the relationships between student nurses, the school, the hospital and health personnel]. PMID- 6907135 TI - [Assistance: experience in the treatment of sexual dysfunction in women]. PMID- 6907136 TI - [Intensive care in pediatrics. 1]. PMID- 6907137 TI - [Experiences in the treatment of sexual dysfunctions in men]. PMID- 6907138 TI - [The organization of home nursing services in Belgium]. PMID- 6907139 TI - [10th anniversary of Schaerbeek's home care services "Home Care"]. PMID- 6907140 TI - [Living and working at the hospital]. PMID- 6907141 TI - [Standard nursing care plans for the operating room]. PMID- 6907143 TI - [Intensive care in pediatrics. 2]. PMID- 6907142 TI - [Psychomotor therapy: an interview with Pesso]. PMID- 6907144 TI - [Theories and concepts in nursing care]. PMID- 6907145 TI - Personally speaking: challenge for action. PMID- 6907146 TI - Florida begins a gerontological nurse practitioner program. PMID- 6907147 TI - A legal opinion: mandatory overtime. PMID- 6907149 TI - Blood pressure plus. PMID- 6907148 TI - Elevation of complement components in diabetes mellitus. AB - The serum proteins composing the complement system play a role in defense against infection and in the generation of immune-mediated disorders. To examine this system three components of the complement system in diabetes have been measured- an element in the classic (antibody-mediated) pathway, C4; an element in the properdin (non-antibody) pathway, C3 activator; and an element common to both pathways, C3. The levels of all three are increased both in diabetics and in individuals with glucose intolerance. In the glucose intolerant subjects elevation occurred either with or without fasting hyperglycemia. The levels of all three complement components were found to be positively correlated with fasting plasma glucose in the glucose intolerant group. An increase of complement components with age was found in the overall study population, and in two individual groups. For this reason a further comparison was made between nondiabetics and diabetics on the basis of age; the diabetic complement increase was still detectable. The levels of individual complement components were correlated with each other in both diabetic and nondiabetic groups. An inverse correlation was found between C3 activator and albumin level. The elevation of all complement components was found to be unrelated to the presence or severity of diabetic microvascular sequelae. The simultaneous development of complement elevation and glucose intolerance strongly suggests a metabolic basis for the increase in its components while the lack of association of complement elevation with diabetic sequelae argues against a role for complement in the pathogenesis of diabetic microangiopathy. PMID- 6907150 TI - A change of life. PMID- 6907152 TI - Recruitment/selection retention. PMID- 6907151 TI - Geriatric nursing audit. PMID- 6907153 TI - Crestview Manor: a caring community. PMID- 6907154 TI - The wheel of aging. PMID- 6907155 TI - Enjoyable activity for everyone. PMID- 6907157 TI - Drugs and the elderly. Could your patient's confusion be caused by drugs? PMID- 6907156 TI - Common concern: "Blueprint for a new age". PMID- 6907158 TI - Nutrition: how can you lower sodium intake? PMID- 6907159 TI - Managing your time. PMID- 6907160 TI - Legal boundaries of nursing conduct. PMID- 6907161 TI - Health fairs. PMID- 6907162 TI - ANA's commission on nursing education. PMID- 6907163 TI - Breakthrough to nursing: "Housekeeping" time. PMID- 6907164 TI - Who cares about health care? PMID- 6907166 TI - Crisis intervention: why me (and you)? PMID- 6907165 TI - Growing up with diabetes mellitus. PMID- 6907167 TI - Pediatric hypertension. PMID- 6907168 TI - Surviving on the job: hints for the new graduate. PMID- 6907169 TI - Genetic polymorphisms of properdin factor B(Bf), the second component (C2), and the fourth component (C4) of complement in leprosy patients and healthy controls from Thailand. PMID- 6907171 TI - [Dirty hands: regulations and limits of asepsis]. PMID- 6907170 TI - Urinary kallikrein activity and renal vascular resistance in the antihypertensive response to thiazide diuretics. AB - To evaluate the mechanism of chronic thiazide diuretic action in hypertension, we treated 19 essential hypertensive white men for 1-month periods on placebo alone and hydrochlorothiazide alone. During therapy, mean arterial pressure (MAP) fell, but radioisotopically determined intravascular volume remained unchanged, suggesting other mechanisms of thiazide action upon blood pressure. In the renal circulation, thiazides did not change renal plasma flow or glomerular filtration rate, but renovascular resistance was diminished, probably at the afferent arteriole. Concomitant with the decline in blood pressure and renovascular resistance, urinary kallikrein excretion increased, from subnormal (hypertensive) levels back into the normal range. The kallikrein increase did not correlate with changes in plasma aldosterone. In addition, patients with blood pressure responses (reduction greater than or equal to 10%) to thiazides (n = 12) had greater increases in kallikrein excretion than those without such a blood pressure decrement (n = 7), suggesting a role for renal kallikrein in the hypotensive response to thiazide diuretics. PMID- 6907172 TI - [Diet of the athlete]. PMID- 6907173 TI - [Management of multiple metabolic overcharge]. PMID- 6907174 TI - [From plethora to famine. Interview by J. Vebret]. PMID- 6907175 TI - [Ionizing radiation: dangers and protective measures]. PMID- 6907176 TI - [Delusions]. PMID- 6907177 TI - [Pityriasis rosea of Gibert]. PMID- 6907180 TI - [Obesity]. PMID- 6907178 TI - [Social security in the framework of the European Economic Community]. PMID- 6907179 TI - [Cerebral edema]. PMID- 6907182 TI - [Declaration of pregnancy]. PMID- 6907181 TI - [Symptomatic treatment of diarrhea]. PMID- 6907183 TI - [Required or recommended vaccines for children]. PMID- 6907185 TI - [An educational and beneficial parent-teacher relationship: bread at all costs, but not at any cost]. PMID- 6907184 TI - [Advantages of long term progestative treatment for women in their forties]. PMID- 6907186 TI - [Retinal detachment]. PMID- 6907187 TI - [Insomnia]. PMID- 6907188 TI - [Hypoglycemic syndrome]. PMID- 6907189 TI - [Panaris]. PMID- 6907190 TI - [Research in tropical disease. New methods of control. World Health Organization]. PMID- 6907191 TI - [International classification of diseases. World Health Organization]. PMID- 6907192 TI - [Interesting therapeutic use of acupuncture]. PMID- 6907195 TI - [Lumbar sympathectomy]. PMID- 6907193 TI - [Electric accidents]. PMID- 6907194 TI - [Psychiatric nursing. Pseudodementia of the elderly]. PMID- 6907196 TI - [Uterine fibroma]. PMID- 6907197 TI - [Rabies. World Health Organization]. PMID- 6907198 TI - [Nursing process and care planning]. PMID- 6907199 TI - [Holidays for children on hemodialysis]. PMID- 6907201 TI - [Systematic structuring of the helping relationship, a pressing need today]. PMID- 6907200 TI - [The future of the nursing profession]. PMID- 6907202 TI - [The well child in the hospital]. PMID- 6907203 TI - [The Regional Union of Chemical Industries]. PMID- 6907204 TI - [Trying to moderate obstetrics]. PMID- 6907207 TI - Health visitors and social workers. PMID- 6907205 TI - [Legal aspects: when the nurse neglects to communicate]. PMID- 6907206 TI - A public image. PMID- 6907208 TI - An adult slimming group. PMID- 6907209 TI - A framework for health visiting: a systems approach. Part 1: The application of systems theory to health visiting. PMID- 6907210 TI - The health mobile. PMID- 6907212 TI - A Well Man Clinic--thoughts for the future. PMID- 6907213 TI - From the grass roots. PMID- 6907211 TI - A register for health visitors? PMID- 6907215 TI - The developing child: behaviour problems in the young child. PMID- 6907216 TI - Psychological influences affecting growth. PMID- 6907214 TI - Inequalities in health. Report of a research working group. PMID- 6907217 TI - The developing child: children with sleep difficulties. PMID- 6907219 TI - A framework for health visiting: a systems approach. Part 2: the nature of health visiting activity. PMID- 6907218 TI - Learning in time: a radical look at health visitor training. PMID- 6907221 TI - British Epilepsy Association. PMID- 6907222 TI - Prospects for a preventive care service for the elderly. PMID- 6907220 TI - Talking about the CETHV. PMID- 6907223 TI - Health visiting the aged. PMID- 6907224 TI - Caring for an elderly relative: a personal experience. PMID- 6907225 TI - Keeping fit in retirement. PMID- 6907226 TI - Know your organization: National Eczema Society. PMID- 6907227 TI - A framework for health visiting: a systems approach. Part 3. The environment and the time dimension. PMID- 6907228 TI - Perinatal and neonatal mortality. PMID- 6907229 TI - NHS reorganization. PMID- 6907230 TI - Social inequalities undiminished. PMID- 6907231 TI - Fathers and childbirth: 'just hold my hand'. PMID- 6907232 TI - Stress during the human life-cycle. PMID- 6907233 TI - A support group for health visitors. PMID- 6907234 TI - Can your Citizens Advice Bureau help you? PMID- 6907236 TI - Is prevention productive work? PMID- 6907235 TI - A health visitor on the Council. PMID- 6907237 TI - Prevention par excellence: the health visitor's task. PMID- 6907238 TI - A 24 hour health visiting service. PMID- 6907239 TI - Evaluation of screening: an epidemiological approach. 1: Measuring the effectiveness of health visitors. PMID- 6907241 TI - Focus on school health: health appraisal/surveillance by school nurses. PMID- 6907240 TI - Smokescreen: a survey on smoking in pregnancy. PMID- 6907242 TI - Prevention of coronary heart disease: is there a role for the health visitor? PMID- 6907243 TI - Changing patterns of childbirth and childcare. PMID- 6907245 TI - Health visiting in the eighties. PMID- 6907244 TI - Health visiting in the 80s. PMID- 6907247 TI - Evaluation of screening: an epidemiological approach. 2: a review of vision screening in pre-school children. PMID- 6907246 TI - The father's role in child health care: is dad an expert too? PMID- 6907248 TI - An evening on call. PMID- 6907249 TI - Family planning: a cautionary tale. PMID- 6907251 TI - Sleeping problems in pre-school children: what to ask and what to do. PMID- 6907250 TI - Know your organizations: Let Live. PMID- 6907252 TI - Evaluation of screening: an epidemiological approach. Part 3: monitoring pre school screening of visual acuity by health visitors-a feasibility study. PMID- 6907253 TI - How mothers help themselves. PMID- 6907254 TI - Know your organizations: toy libraries. PMID- 6907256 TI - The behavioural approach in health visiting. PMID- 6907257 TI - Power: yesterday, today, and tomorrow. PMID- 6907255 TI - The Volunteer Centre. PMID- 6907258 TI - Why certify? PMID- 6907259 TI - Epidemiology of hypertension as a guide to treatment and control. AB - Knowledge of the epidemiology of hypertension can be used as an excellent guide in treatment and control of hypertension in the community. Available evidence on the epidemiology of hypertension that has direct bearing on clinical decisions for diagnosis and treatment can be listed as follows: 1. Frequently distribution of arterial blood pressure in a population of unimodal and continuous. 2. The adverse effects of high blood pressure (e.g., death) are related numerically to the level of blood pressure, both systolic and diastolic. 3. Prevalence of actual hypertension in the community depends upon the variability of blood pressure between occasions of measurement, and the arbitrary cutoff points used in screening. 4. Prevalence rates of actual hypertension in the community are the same for men and women and differ by race; the rate is higher in black than in white subjects. 5. Although the proportion of those cases of hypertension under control has increased dramatically in the United States communities since 1974, a disparity exists between men and women in the degree of their hypertension control. More women (black and white) than men have their hypertension under control. 6. There is an interaction between blood pressure and other risk factors. Decision on treatment should be based on total health profiles of the patient and not just the level of blood pressure. 7. Results of recent experimental epidemiologic studies (HDFP) indicate that judicious and rigorous treatment of mild hypertension in the community is feasible and that such a treatment is successful in reducing total mortality rate in the community by at least 17%. PMID- 6907261 TI - Screening hypertensive patients for surgically reversible causes--unsettled issues. AB - 1. The frequency of surgically reversible hypertension in the general or unselected hypertensive population is not established. Most published studies reporting frequency of surgical hypertension are based on studies from referral centers. 2. Future surveys regarding surgically remediable hypertension should be reported both in terms of frequency and in terms of the actual percent or number of patients who undergo surgical therapy. Studies to date suggest that there is a significant difference between frequency and operated cases. 3. Currently available screening tests for surgical hypertension are not generally recommended except for the serum potassium as a screen for aldosterone adenomas. Other currently available screening tests do not meet the criteria of acceptable tests for mass screening. 4. Medical therapy is a reasonable alternative for selected cases of aldosterone adenomas and is preferred therapy for certain cases of renal artery stenosis. PMID- 6907260 TI - Status of high blood pressure control in California: a preliminary report of a statewide survey. PMID- 6907262 TI - Electrolyte intake, electrolyte excretion, and hypertension. AB - Tribes that exist on a very low salt intake while consuming large amounts of potassium, and whose members are quite small and thin, develop practically no hypertension. Within the Western world little correlation between sodium intake and blood pressure can be found in the untreated patient. However, as individuals with high-normal blood pressure develop further blood pressure elevation on sodium loading, those with a family history of hypertension or high-normal blood pressure should restrict their sodium intake. There is a modest amount of evidence to suggest that potassium protects against the blood pressure-raising effects of sodium. The case for sodium restriction is best demonstrated in the treated hypertensive patient. Modest sodium restriction will enable the treated hypertensive patient to obtain good blood pressure control with much less drug intake and, therefore, less drug side effect. PMID- 6907263 TI - Treatment of hypertensive emergencies. PMID- 6907264 TI - Nursing management of the parenteral drug abuser with infective endocarditis. AB - Caring for the parenteral drug abuser with infective endocarditis is a challenge. In many ways, the nursing care needed for these patients differs from that needed by other patients with infective endocarditis. This article has identified some of the important considerations: maximizing the effectiveness of the treatment regimen, fostering patient adaptation to hospitalization, and planning for discharge to minimize the risk of recurrence. By understanding the nature of drug abuse and of infective endocarditis, and by understanding how they interact to create a particular set of problems in the parenteral drug abuser with infective endocarditis, the nurse can provide optimal nursing management for these patients. PMID- 6907265 TI - Nurse retention in burn care: a report of 14 years' experience. PMID- 6907266 TI - Hypotensive crises: identifying the high-risk patient on hemodialysis. AB - Hypotensive crises in patients on hemodialysis remains a substantial problem for both patient and nurse. Awareness of its causes, research-develop assessment tools, and their application in the field may minimize this problem. Nurses play a prominent role in a patient's hypotensive crisis by administering, monitoring, and evaluating the effectiveness of intervention measures used to reverse this hemodynamic state. This study has provided a nursing assessment tool that will enable nurses to predict systolic risk levels and aid them in deciding when to initiate intervention measures. PMID- 6907267 TI - A concordant pattern. PMID- 6907268 TI - Can heparin cause clotting? PMID- 6907269 TI - An unusual complication of acute myocardial infarction. AB - Right ventricular infarction occurs exclusively as a complication of a transmural inferoseptal left ventricular infarction. Up to 50% of patients with transmural inferoseptal infarction may have associated right ventricular involvement. In the majority of cases, however, the right ventricular involvement is clinically silent. However, significant right ventricular infarction is being recognized with greater frequency. Clinically, distended neck veins and hypotension are frequent findings in acute right ventricular infarction and their presence should suggest the diagnosis. Damage to the right ventricle causes poor contractility and output, and thus the right ventricle functions more as a passive conduit to the left ventricle. The patient should lie with the bed flat to improve volume return to the right and left ventricles. Volume expansion is used when left ventricular filling pressure is low and there is clinical evidence of poor peripheral perfusion. PMID- 6907270 TI - Comparative activity of BRL 25.000 with amoxycillin against resistant clinical isolates. PMID- 6907271 TI - Vancomycin therapy of experimental pneumococcal meningitis caused by penicillin sensitive and resistant strains. PMID- 6907272 TI - Properties of the lactose transport system in Klebsiella sp. strain CT-1. AB - Highly purified [D-glucose-1-14C]lactose has been used to study the transport of lactose by Klebsiella sp. strain CT-1. Strain CT-1 transports lactose by a lactose-inducible system that exhibited an apparent Km of 6 mM lactose and an apparent Vmax of 140 nmol/min per mg of cell protein. Lactose uptake was inhibited competitively by o-nitrophenyl-beta-D-galactoside with a Ki value of 8 mM, but was not inhibited by thio-beta-methyl-galactoside. D-Glucose, D-mannose, 2-deoxyglucose, and alpha-methyl-D-glucoside also inhibited lactose uptake. Phosphoenolpyruvate-dependent hydrolysis of o-nitrophenyl-beta-D-galactoside and lactose-dependent release of pyruvate from phosphoenolpyruvate by benzene-treated CT-1 cells showed that CT-1 transports lactose by a phosphoenolpyruvate:sugar phosphotransferase system. Correlations between the growth rate of CT-1 on lactose and properties of the transport system indicated that transport is the rate limiting step in utilization of lactose. PMID- 6907274 TI - Notes on continuing education: Bloom's theory of school learning. PMID- 6907275 TI - Evaluation: the key to accountability in continuing education. PMID- 6907273 TI - Stimulation of human leukocyte elastase by platelet factor 4. Physiologic, morphologic, and biochemical effects on hamster lungs in vitro. AB - The purpose of this study was to determine if human platelet factor 4 (PF4) stimulates human leukocyte elastase (HLE) against lung elastin. Lung elastin was purified from hamster lungs and tritiated by reduction with NaB3H4. We found that HLE activity against this substrate is increased by concentrations of PF4 as low as 1.6 microgram/ml, and that this stimulation increased linearly with additional PF4. Lungs removed from hamsters and inflated with solutions containing buffer alone, low dose HLE, HLE plus PF4, or PF4 alone were incubated for 2 h at 37 degrees C. Whereas low-dose HLE failed to lower lung elastin when compared to control animals, HLE stimulated by PF4 lowered lung elastin by 20%. PF4 alone had no effect. Furthermore, low-dose HLE failed to alter the mechanical properties of hamster lungs as measured by pressure-volume curves in saline, although there was a significant loss of lung elasticity in the mid- and high-lung volume ranges in lungs treated with HLE and PF4. Morphologic studies revealed that low dose HLE resulted in a minimal emphysemalike lesion whereas HlE plus PF4 caused a significantly more severe lesion. PF4 is capable of stimulating HLE against lung elastin, and this effect may have a role in the pathogenesis of emphysema. PMID- 6907276 TI - Evaluation of Maine's telelecture continuing education program: part I. PMID- 6907277 TI - Designing practical continuing education program evaluation forms. PMID- 6907278 TI - Method for detection of enzymatic activities which use aminoacyl-tRNA as a substrate. AB - A method for detection of enzymatic activities which use aminoacyl-tRNA is described. It is based on the synthesis of aminoacyl-tRNA in the reaction mixture (in situ) without additional purification. The results are the same as when using purified AA-tRNA. PMID- 6907279 TI - For nursing homes: a mental health charting instrument. PMID- 6907280 TI - Aging each other. PMID- 6907281 TI - The challenge of gerontological nursing in a nursing home. PMID- 6907282 TI - Effect of a gerontological educational experience on adolescent girls' attitudes toward the elderly. PMID- 6907283 TI - Dining experiences of the institutionalized aged. PMID- 6907284 TI - Drugs and the elderly patient. PMID- 6907285 TI - Abuse and neglect among the elderly. PMID- 6907287 TI - Utilizing research in the placement of the elderly. PMID- 6907286 TI - Nocturnal behavior of selected institutionalized adults. PMID- 6907288 TI - Elastase +/- soybean trypsin inhibitor dissociation of rat oral mucosa: ultrastructural and oxidative metabolic destructive changes in isolated, epithelial and dermal mitochondria after dissociation. AB - Epithelial and connective tissue compartments of rat oral mucosa were dissociated after incubation with elastase +/- soybean trypsin inhibitor (SBTI). Elastase + SBTI induced greater ultrastructural damage within the dissociated compartments than elastase alone. The basal lamina remained with the epithelial layer after elastase separation and was destroyed after exposure to elastase + SBTI. Isolated epithelial mitochondria were more severely damaged ultrastructurally after elastase + SBTI separation of the compartment than those prepared after exposure to elastase alone. Isolated fibroblast mitochondria were damage to the same extent after dissociation of the compartment with either medium. Oxidative metabolism and mitochondrial recoveries declined significantly after exposure to either dissociating medium. Cytochrome oxidase activity was significantly greater than succinic cytochrome c reductase in the control and experimental groups. Oxidative metabolism was found to be significantly greater in the connective tissue compartment than the epithelial compartment after dissociation of immature rat oral mucosa. Our data suggests that caution be utilized in assessing cellular viability and oxidative metabolism in tissue compartments immediately after their dissociation by proteolytic enzymes. PMID- 6907289 TI - A hormonal assessment of bovine parturient paresis: evidence for a role of oestrogen. AB - A comparative assessment was made of the hormonal control of calcium homeostasis in eight dairy cows which developed parturient paresis and in seven normal animals from the same herd. Plasma levels of calcium, phosphorus, magnesium, free hydroxyproline, 25-hydroxycholecalciferol (25-OHD), 1,25-dihydroxycholecalciferol (1,25-(OH)2D), parathyroid hormone, calcitonin, prolactin and oestrogen were monitored from 30 days prepartum to 15 days post partum. Prepartum levels of plasma calcium, hydroxyproline and calcitonin were depressed in the paretic animals, and plasma levels of phosphorus and oestrogen were elevated. Plasma levels of 25-OHD remained stable in both groups, whereas levels of 1,25-(OH)2D, parathyroid hormone and prolactin rose sharply at parturition. Plasma hydroxyproline, an index of bone resorption, began to rise 2 days prepartum in the control cows but not until 2 days post partum in the paretic cows. The data indicate that bone resorption was inhibited in the paretic group at the onset of lactation, and that a decreased capacity for bone resorption is a major factor in the susceptibility of some cows to this disease. The failure of the paretic animals to resorb bone was not associated with an inability to synthesize the calcium-mobilizing hormones parathyroid hormone or 1,25-(OH)2D, or to regulate the production of calcitonin. However, hypocalcaemia in the affected animals was associated with a significantly higher plasma level of oestrogen (a known inhibitor of bone resorption) in the immediate prepartum period. Following parturition, plasma levels of oestrogen fell rapidly and active bone resorption ensued in the paretic animals. PMID- 6907291 TI - Compliance with therapeutic regimens: issues, answers, and research questions. PMID- 6907290 TI - Characterization of an initiating cell-free protein synthesis system derived from rabbit brain. AB - Protein synthesis in the brain is known to be affected by a wide range of treatments. The detailed analysis of the mechanisms that are involved would be facilitated by the development of cell-free translation systems derived from brain tissue. To date, brain cell-free systems have not been fully characterized to demonstrate a capacity for initiation of translation. The following criteria were utilized to demonstrate that a cell-free protein synthesis system derived from rabbit brain was capable of initiation in vitro: (a) sensitivity of cell free translation to the initiation inhibitor aurintricarboxylic acid (ATA); (b) binding of [35S]Met-tRNAf to 40S and 80S initiation complexes; (c) incorporation of labeled initiation methionine into high-molecular-weight proteins; and (d) the association of labeled exogenous mRNA with polysomes. The optimum conditions for amino acid incorporation in this system were 4 mM-Mg2+, 140 mM-K+, and pH 7.55. Incorporation was dependent on the addition of ATP, GTP, and an energy-generating system. Cell-free protein synthesis reflected the normal process, since a similar spectrum of proteins was synthesized in vitro and in vivo. This initiating cell free translation system should have wide application in the analysis of the mechanisms whereby various treatments affect protein synthesis in the brain. PMID- 6907293 TI - Prolactin producing pituitary adenomas. PMID- 6907292 TI - Resolution of an ethical issue in the hospitalized adult neurosurgical patient. PMID- 6907294 TI - The insidious spinal cord tumor. PMID- 6907295 TI - Plasmapheresis as a treatment for myasthenia gravis. PMID- 6907296 TI - Overview of multiple sclerosis and nursing care of the M.S. patient. PMID- 6907297 TI - The patient undergoing craniofacial surgery: nursing assessment and intervention. PMID- 6907299 TI - Minority recruitment. PMID- 6907300 TI - Fetal movement counts: an assessment tool. PMID- 6907298 TI - Primary care nursing: the "how-to" of transition. PMID- 6907301 TI - Fetal movement and fetal outcome in a low-risk population. PMID- 6907303 TI - Duration of breastfeeding in women with varied prenatal preparation and postpartum followup. PMID- 6907302 TI - Nurse-midwife involvement in medical student education: the pelvic examination. PMID- 6907304 TI - Nestle Boycott. PMID- 6907305 TI - Improving the outcome of pregnancy through increased utilization of midwives. PMID- 6907306 TI - Weaning practices. PMID- 6907307 TI - What happens to CNMs if there are too many obstetricians in 1990? PMID- 6907308 TI - Controversies in maternal effort during labor and delivery. PMID- 6907309 TI - Collective bargaining: a personal professional experience and an ACNM imperative. PMID- 6907310 TI - A faculty fellowship at Maternity Center Association: an innovative approach in nurse-midwifery continuing education. PMID- 6907312 TI - The bottle baby controversy: a rejoinder. PMID- 6907311 TI - Comparison of interactional deprivation of the mother with a transported versus nontransported premature infant. PMID- 6907313 TI - Intact perineum: a slow delivery of the head does not adversely affect the outcome of the newborn. PMID- 6907315 TI - Anti-peptic ulcer agents - Part IV. Anticholinergics. PMID- 6907316 TI - [Are you infecting your patients? Prevention goes a long way in infection control]. PMID- 6907317 TI - Back to basics: communicating with your aphasic patients. PMID- 6907318 TI - Respiratory care for patients with amyotrophic lateral sclerosis. PMID- 6907319 TI - Nursing care considerations for the ALS patient. PMID- 6907320 TI - Wishes, midlife, and nursing. PMID- 6907314 TI - The effect of pargyline pretreatment on the enhancement of the exocytotic release of norepinephrine during nerve stimulation which is induced by a benzoquinolizine compound with reserpine-like properties. AB - Pretreatment of guinea pigs with paragyline (100 mg/kg i.p., 18 hr before sacrifice) resulted in a significant depression in the overflow of endogenous norepinephrine (NE), total 3H, [3H]NE and dopamine beta-hydroxylase associated with stimulation of the sympathetic nerves to the isolated heart. The depression was pronounced at 5 Hz. At 10 Hz, pargyline pretreatment was without effect. The effect on dopamine beta-hydroxylase output was not as great as that on total 3H, [3H]NE or endogenous NE release, suggesting the possibility that more than one mechanism is responsible for the depressant effect of monoamine oxidase (MAO) inhibition on sympathetic neurotransmission. A benzoquinolizine compound with reserpine-like properties, 2-hydroxy-2-ethyl-3-isobutyl-9, 10 dimethoxy,1,2,3,4,6,7-hexahydro-11b-H-benzo[alpha]quinolizine (RO 4-1284), increased the nerve stimulation-mediated overflow of all the measured indices of neurotransmitter release, in addition to producing a significant increase in the spontaneous overflow of 3H from hearts of untreated guinea pigs. The augmentation of nerve-stimulated NE release by RO 4-1284 was even greater in hearts from pargyline pretreated guinea pigs. These results would tend to eliminate a causal role for a deaminated metabolite of NE in the augmenting effect on release seen with RO 4-1284. Conversely, the inhibition of neurotransmitter release associated with MAO inhibition is not mediated by the blockade in the formation of deaminated catecholamine metabolites. Enhancement in the negative feedback mechanism on release and the accumulation of false transmitter probably account for the local effects of MAO inhibitors on neurally mediated norepinephrine release. PMID- 6907321 TI - What's so special about my specialty? Geriatric nursing. PMID- 6907322 TI - Giving your best to nursing: is it worth it? PMID- 6907323 TI - The conversation game. PMID- 6907324 TI - Radiation: an invisible two-edged sword. PMID- 6907325 TI - When your patient is a nurse. PMID- 6907326 TI - Face the issues. PMID- 6907327 TI - Getting the patient out of bed. PMID- 6907328 TI - Bill of rights for nursing home residents. PMID- 6907330 TI - [A keypoint in nursing: primary care. Discussion]. PMID- 6907329 TI - Methicillin-resistant Staphylococcus aureus osteomyelitis in a neonate. PMID- 6907331 TI - [Primary health care - its conceptual interpretation]. PMID- 6907332 TI - [Primary health care and its relationship to midwifery activities]. PMID- 6907333 TI - [A survey based on the delivery records of the Kofu Municipal Hospital]. PMID- 6907334 TI - [Comparative obstetrics of monkeys and man. 10. Sex and reproduction of primates (IV)]. PMID- 6907335 TI - [Reflection of a 3-month nursing seminar]. PMID- 6907336 TI - [Report by a nurse visiting the Philippines]. PMID- 6907337 TI - Factor B and C3b inactivator clearance in patients with proteinuria. PMID- 6907338 TI - [Significance of medical and health statistics in nursing activities]. PMID- 6907339 TI - [Interpretation of health and medical statistics: statistics concerning health facilities and their personnel]. PMID- 6907340 TI - [Medical and health statistics and their interpretation: morbidity statistics]. PMID- 6907341 TI - [Health and medical statistics and their interpretation: statistics concerning health insurance]. PMID- 6907342 TI - [Medical and health statistics and their interpretation: statistics concerning maternal and child health]. PMID- 6907343 TI - [Health and medical statistics and their interpretation: health statistics concerning adult diseases]. PMID- 6907344 TI - [Medical and health statistics and their interpretation: health statistics concerning diseases of the aged]. PMID- 6907345 TI - [Medical and health statistics and their interpretation: statistics concerning mental health]. PMID- 6907346 TI - [Statistics concerning population dynamics and the life table]. PMID- 6907347 TI - [Nutrition survey]. PMID- 6907348 TI - [National health survey: prevalent trends]. PMID- 6907349 TI - [Patient surveys and the prevalent trends]. PMID- 6907350 TI - [Nursing and medical information]. PMID- 6907352 TI - [Methods of questionnaire distribution and sampling]. PMID- 6907353 TI - [Focal points in modern medicine. 3. The food habits of the Japanese and their health--the Japanese and their diet]. PMID- 6907351 TI - [Accurate statistical analysis and methods of sampling]. PMID- 6907354 TI - [High risk pregnancy - with special reference to the care of the fetus]. PMID- 6907355 TI - [Pregnancy of aged patients and their health care instructions]. PMID- 6907357 TI - [Management of severe pregnancy toxemias and fetal growth]. PMID- 6907356 TI - [Prediction of pregnancy toxemias - the significance of the roll-over test]. PMID- 6907358 TI - [Preparation of a check list for prediction of high risk pregnancy and its effects]. PMID- 6907359 TI - [Nursing of a patient with recurrence of severe pregnancy toxemia]. PMID- 6907360 TI - [A study on weight control of pregnant patients]. PMID- 6907361 TI - [Nephrotic syndrome in pregnancy and problems in nursing care]. PMID- 6907362 TI - [Conference: care of patients with severe pregnancy toxemias - the nursing process from ambulatory nursing care to continued nursing after delivery]. PMID- 6907363 TI - [Urination anomalies]. PMID- 6907364 TI - [Mechanisms of urine formation and urination]. PMID- 6907365 TI - [Psychosomatic medicine and urination abnormality]. PMID- 6907366 TI - [Nursing of aged patients wit difficulties in unassisted urination and defecation]. PMID- 6907368 TI - [Nursing of a severely burned child in a mixed ward - total care with special reference to the stage liable to infections]. PMID- 6907367 TI - [Dialysis-associated nursing as a speciality]. PMID- 6907369 TI - [Pain caused by immobilization during surgery and its nursing]. PMID- 6907370 TI - [Case study in nursing of a patient with hypothyroidism]. PMID- 6907371 TI - [An observation on the status of acute cerebral apoplexy]. PMID- 6907372 TI - [Bedside guidance in heart diseases. Symptoms and diagnosis of heart diseases]. PMID- 6907374 TI - [Alcohol-related problems and alcohol dependence syndrome--establishment of their concepts and diagnosis]. PMID- 6907373 TI - [Nursing of aged patients with fractures - the role of nursing in prevention of senile dementia]. PMID- 6907375 TI - [Psychotherapy of alcohol-dependent patients--group therapy and beyond]. PMID- 6907376 TI - [Application of the introspective therapy to alcohol-dependent patients and its significance]. PMID- 6907379 TI - [Physical care and nursing plans for alcoholic patients during the detoxication period]. PMID- 6907378 TI - [Socio-psychiatric approach in the treatment of alcohol-dependence syndrome]. PMID- 6907377 TI - [Prognosis of alcohol-dependent patients and their families]. PMID- 6907380 TI - [Therapy, nursing and prognosis of alcoholic patients during rehabilitation]. PMID- 6907382 TI - [Instructions given to the families of local alcohol-dependent patients]. PMID- 6907381 TI - [Care of patients with chronic gastrointestinal diseases caused by alcohol dependence]. PMID- 6907383 TI - [Case conference: therapy and nursing of an alcohol-dependent patient with repeated hospitalization]. PMID- 6907384 TI - [Jaundice]. PMID- 6907385 TI - [Jaundice: functions of the liver and it's disorders]. PMID- 6907386 TI - [Classification of jaundice and management of acute cases]. PMID- 6907387 TI - [Jaundice: changes of the icterometric readings due to test conditions]. PMID- 6907388 TI - [Evaluation of neonatal hyperbilirubinemia--neonatal jaundice and icterometric readings]. PMID- 6907389 TI - [An approach to a patient with multiple sclerosis--planning of nursing in preparation for discharge from the hospital]. PMID- 6907390 TI - [Bedside guidance in cardiology. 5. Basis of therapy and nursing]. PMID- 6907392 TI - [Diagnosis by comprehensive imaging]. PMID- 6907393 TI - [Interpretation of the imaging information based on data theory]. PMID- 6907391 TI - [Environmental control of the operating room for the prevention of infection]. PMID- 6907394 TI - [Diagnosis of cancer and imaging]. PMID- 6907395 TI - [Imaging in neurosurgery]. PMID- 6907396 TI - [Imaging in emergency services]. PMID- 6907397 TI - [CT scanner]. PMID- 6907398 TI - [Angiography]. PMID- 6907399 TI - [Ultrasonography]. PMID- 6907400 TI - [Thermography]. PMID- 6907401 TI - [Echocardiography]. PMID- 6907402 TI - [Radioisotope dynamic study]. PMID- 6907403 TI - [Cytodiagnosis and image processing]. PMID- 6907405 TI - [Information processing in imaging and its concept]. PMID- 6907404 TI - [Radiography]. PMID- 6907407 TI - [Diseases causing obesity and emaciation--causative factors and pathophysiology]. PMID- 6907406 TI - [The focal point in modern medicine. 2. Medical science with emphasis on individuals. A discussion]. PMID- 6907409 TI - [Description of obese patients seen at a health examination center and the focal points in their health education]. PMID- 6907408 TI - [Clinical conditions and physiopathology of simple obesity]. PMID- 6907410 TI - [Psychophysiologic approach to pathologically thin patients--care of patients with anorexia nervosa]. PMID- 6907411 TI - [Needs of patients with neurologic diseases and their categorization]. PMID- 6907412 TI - [Bedside guidance in heart diseases. 6. Ischemic heart disease]. PMID- 6907413 TI - [Diagnosis, prediction, and prevention of fulminant hepatitis]. PMID- 6907416 TI - [Artificial liver--current progress]. PMID- 6907414 TI - [Treatment of fulminant hepatitis--recent developments]. PMID- 6907415 TI - [Treatment of fulminant hepatitis--prevention of complications and plasma exchange therapy]. PMID- 6907417 TI - [Total care and nursing in the acute stage of fulminant hepatitis]. PMID- 6907418 TI - [Management and nursing of a patient with fulminant hepatitis receiving plasma exchange]. PMID- 6907419 TI - [Treatment and nursing of a patient with fulminant hepatitis saved by hemoperfusion]. PMID- 6907420 TI - [Development of viral hepatitis into a fulminant stage and pathogenesis of hepatic failure]. PMID- 6907422 TI - [Conference: therapeutic examples in fulminant hepatitis]. PMID- 6907421 TI - [Treatment and care of hepatic coma]. PMID- 6907423 TI - [Medical information to determine nursing actions for patients with fulminant hepatitis--with special reference maintaining bed rest]. PMID- 6907424 TI - [Theories on iatrogenic incidents based on human relationship--with special reference to responsibilities of the physician and nurse]. PMID- 6907425 TI - [Proposal of a term: "diseases caused by habits"--the role of nursing in life planning. Discussion]. PMID- 6907426 TI - [The medical standard and nursing duties]. PMID- 6907428 TI - [Life and nursing of hospitalized children. A speech at the 29th Igakushoin Nursing Seminar]. PMID- 6907427 TI - [Iatrogenic incidents and judgement of errors--instances with involvement of nurses]. PMID- 6907429 TI - [Iatrogenic incidents and compensation]. PMID- 6907430 TI - [Bedside nursing. Assistance of a patient at the terminal stage of lung cancer- relief of cancerous pain with administration of the Brompton cocktail]. PMID- 6907431 TI - [Iatrogenic incidents and the responsibility of the nurse]. PMID- 6907432 TI - [Bedside nursing. Assistance of a patient in the terminal stage of gastric cancer who has learned the nature of her illness]. PMID- 6907433 TI - [Medical records--their significance in prevention of iatrogenic accidents]. PMID- 6907434 TI - [Bedside nursing. Psychological assistance of a dying leukemic child]. PMID- 6907435 TI - [Emergency nursing duties--prevention of nursing-related accidents]. PMID- 6907436 TI - [Bedside nursing. Re-evaluation of health instruction given during home visits to dialysis patients]. PMID- 6907437 TI - [Problems of injection-related accidents--recent development]. PMID- 6907438 TI - [Observation by students. Lessons from the first basic clinical training--through the observation and care of patients in grave conditions]. PMID- 6907439 TI - [Nursing duties and prevention of iatrogenic incidents--with special reference to nursing planning and nursing sequence]. PMID- 6907440 TI - [Scene of life and death. Description of a nurse sharing the life of her patients. 2. A nurse at a special home for the aged without families. 1]. PMID- 6907441 TI - [Discussion. Nursing duties and nursing-related incidents--a thought on prevention of accidents]. PMID- 6907442 TI - [Lessons in computers. 2. Communication with the computer]. PMID- 6907443 TI - [Sex at the clinical scene. 13. Sex education]. PMID- 6907444 TI - [Questions and answers on respiratory diseases. 11. Mediastinal cancer]. PMID- 6907445 TI - [Disinfection and sterilization. 7. Disinfection, sterilization and the operating room]. PMID- 6907446 TI - [Profile of a nurse. Ms. Emiko Imada, a volunteer member of an organization of cervical cord injured patients]. PMID- 6907447 TI - [New medical problems and medical ethics]. PMID- 6907449 TI - [Neural paralysis caused by erroneous injections]. PMID- 6907448 TI - [Life with the Japanese population in Argentina. 2. Medical care in Argentina]. PMID- 6907450 TI - [Care in preparation for colonoscopic examination]. PMID- 6907451 TI - [Focal points in modern medicine. 5. The life of the aged in Japan--the aging society in view of population dynamics]. PMID- 6907452 TI - [Diagnosis of senile dementia: the criteria for determination of psychological aging]. PMID- 6907453 TI - [Various types of senile dementia and therapeutic approaches]. PMID- 6907455 TI - [Dementia of aged, bedridden patients and effectiveness of rehabilitation technics]. PMID- 6907454 TI - [Prognosis of senile dementia]. PMID- 6907456 TI - [Psychological characteristics of aged, demented patients and understanding of their mental processes]. PMID- 6907457 TI - [Planning of nursing of hospitalized dementia patients]. PMID- 6907458 TI - [Approach to patients with senile dementia--in psychiatric care]. PMID- 6907459 TI - [Abnormal behaviors of aged patients following surgical procedures]. PMID- 6907461 TI - [Conference: nursing of aged, demented patients--with special reference to a case observed at an orthopedic department]. PMID- 6907460 TI - [Families of aged, demented patients being cared for at home and assistance extended to them--activities of an organization of families with aged demented patients]. PMID- 6907462 TI - [Innovation in preparation of water to be used for topical cooling in open heart surgery]. PMID- 6907464 TI - [Etiology of anemia]. PMID- 6907463 TI - [Easing of pain caused by gastric intubation--intubation by the patient and application of a smaller tube]. PMID- 6907465 TI - [Physiopathology and treatment of anemia]. PMID- 6907466 TI - [Preparation and evaluation of the standard for health guidance of pregnant patients with anemia]. PMID- 6907467 TI - [Understanding the needs of heart patients]. PMID- 6907469 TI - [Nursing through touch and hearing]. PMID- 6907468 TI - [Bedside guidance of heart diseases. 7. Hypertension]. PMID- 6907470 TI - [An unforgettable nursing student]. PMID- 6907471 TI - [An encounter with a student: a viewpoint of a nursing school director]. PMID- 6907472 TI - [Identity of nursing students]. PMID- 6907473 TI - [Initiation into a woman's profession: identity problems in the status transition of coed to student nurse]. PMID- 6907474 TI - [Minerva's light: a thought on man and nursing. (1). A conversation with Caligula]. PMID- 6907475 TI - [In search of a new educational encounter. 1. Teaching to nurture the nursing attitude: educational direction and educational technic]. PMID- 6907476 TI - [Encounters with nursing students]. PMID- 6907477 TI - Nursing and nursing education in the last 35 years since the end of world war II. (2). PMID- 6907478 TI - Minerva's light: unpretentious thoughts on nursing and man. (2). Compassion and sympathy. PMID- 6907480 TI - The basis of nursing: through an interaction with a patient. PMID- 6907479 TI - Overcoming the undue emphasis on objectivity in nursing study. PMID- 6907481 TI - Self expression. PMID- 6907482 TI - Lessons in clinical training: responsibility of the instructor. PMID- 6907483 TI - Participation in the clinical scene and lessons from the experience--a viewpoint of the instructor. PMID- 6907484 TI - Initiation into a women's profession: identity problems in the status transition of coed to student nurse. PMID- 6907485 TI - Record of clinical training in pediatric nursing: planning based on the nursing process records (3). PMID- 6907486 TI - [Improvement of nursing training at a public health clinic. Transition from individual training to group training: a trail at Osaka-fu]. PMID- 6907487 TI - [Improvement in nursing training at a public health clinic. Group training of public health nursing students and reception at the public health clinic]. PMID- 6907489 TI - [Refusal by the public health clinic of the transfer of the program of health examination of 1 1/2-year-olds to municipal governments]. PMID- 6907488 TI - [Discussion: toward more responsible education. Efforts by the nursing schools in response to the voice of public health nurses on the job]. PMID- 6907491 TI - [Nursing education at the Kashimir region, India, and the relationship between nursing and regional characteristics]. PMID- 6907490 TI - [An attempt at unification of basic nursing and public health nursing education programs - a plan to organize the curricula with emphasis on public health nursing theories]. PMID- 6907494 TI - Effects of tactile and kinesthetic stimulation on premature infants. AB - Forty premature infants, divided equally into matched treatment and control groups, were studied to determine the effect of compensatory tactile and kinesthetic stimulation on clinical course. The treatment group received a 15 minute period of tactile and kinesthetic stimulation once daily on Days 1-10 postpartum; control group received routine care. Treated infants showed increased stooling frequency on Days 5-10, and increased feeding intake on Days 6-10. Treated infants gained increasingly more weight each day, but these differences did not reach statistical significance. These results suggest that single daily stimulation treatments in the first 10 days postpartum were sufficient to enhance the clinical course of premature infants. PMID- 6907493 TI - Maternity nurses' knowledge of factors promoting successful breastfeeding. A survey at two hospitals. AB - An investigator-designed questionnaire was used to survey 53 RNs and LPNs at two urban hospitals concerning knowledge for support of breastfeeding mothers. Maternity nurses demonstrated limited knowledge, especially in drugs, maternal emotions, and neonatal physiology as related to breastfeeding. Level of education affected test scores positively; length of experience affected test scores negatively. PMID- 6907492 TI - Assessing postpartum adjustment. A pilot study. AB - Utilizing crisis theory, the stages of growth and development, and a theory of role transition and enactment, a series of questionnaires was developed as a clinical tool to study women's adaptation to motherhood during six weeks postpartum. The tool was tested on six women. Results suggest that the postpartum is indeed a critical period of identity reformation and role transition. Theories are developed for a framework, and a timetable for nursing intervention is given. PMID- 6907495 TI - Perinatal assessment. AB - The role of the nurse in early recognition of risk factors in the perinatal period is very important. The author suggests that obstetrical units use a perinatal nursing team whose role would include the careful assessment of mother and infant for risk factors during the prenatal, intrapartal, and immediate neonatal periods. The perinatal assessment guide accompanying the text offers a comprehensive compilation of data to assist in the identification of perinatal risk factors. This guide will be useful for nurses working in obstetrical units and for nursing instructors teaching student nurses maternal-newborn nursing assessment. PMID- 6907498 TI - Patient comfort during pelvic examination. New foot supports vs metal stirrups. AB - One hundred women patients at a midwestern university health center were randomly assigned to a control or experimental group to measure statistically comfort levels of new foot supports vs. traditional metal stirrups during pelvic examinations. Written comments were also obtained. Analyses using the t test demonstrated a significant positive change in attitude in the experimental group. PMID- 6907496 TI - Parturition care planning. AB - Nursing care planning is not a new concept, but in contemporary nursing, this tool is taking on new meaning. In an area such as labor and delivery, the concept of the nursing process must be scrutinized and adapted to facilitate its usefulness in providing optimum care of the parturient. A perspective on the scope of care planning, its benefits to the parturient, and its value and implications is presented. PMID- 6907497 TI - Epidural anesthesia for obstetric patients. AB - The use of epidural anesthesia for the obstetric patient is increasing in many areas of the country. The maternity nurse needs to have a basic understanding of the technique used by the physician to initiate this type of anesthesia, and also has a responsibility to know the contraindications, possible complications, and disadvantages and advantages of epidural anesthesia. This information is presented below. Skilled nursing and medical management will reduce the potential risks of epidural anesthesia for both the mother and fetus. PMID- 6907503 TI - Tasks of infertile couples. AB - The author presents four psychological tasks that face infertile couples as they attempt to deal with the childlessness and restore stability to their lives. Each task is discussed with attention to how the nurse can assist couples in dealing with their infertility. Emphasis is placed on the role of the nurse as facilitator, with the couple being the ones who must work through the problem. PMID- 6907502 TI - Zinc insufficiency during pregnancy. A review. AB - Zinc deficiency has been found to cause problems in parturition and in the growth and development of the offspring. There are several groups of pregnant women at known risk of developing a zinc insufficiency; these include vegetarians, alcoholics, teenagers, women with multiple pregnancies, and women with impaired intestinal absorption of zinc. Nurses need to be able to identify the population at risk and to offer dietary counseling. PMID- 6907500 TI - The nurse role in parent-infant bonding. Overview, assessment, intervention. AB - The recognition of appropriate and inappropriate attachment behavior is vital to maternal health and self-esteem and effective infant growth and development. An overview of parent-infant bonding is presented, followed by a discussion of the principles and methods of assessment and intervention. PMID- 6907501 TI - Early postpartum separation and maternal attachment to twins. AB - A mother's attachment to her newborn twins was delayed due to a postpartal maternal illness. Attachment as affected by twin births and separation from the mother is reviewed. Nursing actions, designed to facilitate attachment, are described as encompassing the needs of the whole family. Use of these concepts in similar situations is discussed. PMID- 6907499 TI - The evolution of an antepartum testing program. PMID- 6907504 TI - Participation: the key to learning for patients in antepartal clinics. AB - An approach to patient education which recognized successful participation in the learning process as a key factor in providing information for antepartal clinic patients, known to be poorly motivated, was instituted without changing any system or organization and using a minimal amount of nursing and patient time. Important information on care during pregnancy, labor and delivery, and care of the newborn was shared. Group process also provided a vehicle for expression of feelings, opportunity for reassurance, and direction for particular action. The difficulties inherent in this approach to learning are recognized and recommendations are made for dealing with them. PMID- 6907505 TI - Maternal practice and attitudes toward breastfeeding. AB - An age-graded sample of 411 New York City mothers is assessed to evaluate the direction and amount of change in incidence of breastfeeding. Social and demographic factors are considered and are found to have little trend effect. This limited sample fails to indicate any increase in breastfeeding in the 1970s, as compared to earlier decades. However, maternal attitudes are more positive toward breastfeeding than toward bottlefeeding; and some ethnic, economic, and sociocultural factors do affect decision to breastfeed. PMID- 6907506 TI - Portrait of a newborn. AB - To discover whether the American woman has a preconceived idea of her newborn's appearance, ten primigravidas were asked to draw their newborns-to-be and were interviewed about their expectations. Responses were analyzed for recurring themes and compared with a stereotypical baby described by Lorenz. The informants' general descriptions of their newborns-to-be were specific to the particular family. The newborns were closer in appearance to an older baby than to a newborn. The informants' newborns had two of the Lorenz's six stereotypical attributes. PMID- 6907508 TI - [Crib death]. PMID- 6907509 TI - [Aspects of present-day maternity care]. PMID- 6907507 TI - [Diagnosis and prevention of developmental disorders]. PMID- 6907510 TI - [Training of candidates of health care at Kuopio College]. PMID- 6907511 TI - [Gynecological genital herpes infections]. PMID- 6907512 TI - [Operation Family]. PMID- 6907513 TI - [In Sweden a pregnancy allocation has been added to the family allocation]. PMID- 6907514 TI - [The outlook for 1981]. PMID- 6907515 TI - [Family planning in Finland in the 1970s]. PMID- 6907516 TI - [The Finnish registry of congenital malformations and its application in epidemiological studies]. PMID- 6907517 TI - [Psychological aspects in contraception counseling]. PMID- 6907518 TI - [That marvelous telemetry equipment]. PMID- 6907519 TI - [Gynecologic health tests from the woman's viewpoint]. PMID- 6907520 TI - [Skin and psyche: central nervous system and skin develop from the same germ layers]. PMID- 6907521 TI - [Overcoming frustration]. PMID- 6907522 TI - [Paradox and paradox therapy. Therapy meeting in Bad Boll: experiences with human fundamental experiences]. PMID- 6907524 TI - [Ergometry in the diagnosis of stress-induced coronary insufficiency]. PMID- 6907523 TI - [A way out of speechlessness. Music therapy opens new life chances to mute and multiple handicapped children]. PMID- 6907525 TI - [Hypertensive patients: self-assessment of blood pressure]. PMID- 6907526 TI - [Sufficient working positions for community health nurses. Opportunities for recruits]. PMID- 6907528 TI - [Will nursing be called to account? Questionable advantages of rationalization in the hospital]. PMID- 6907529 TI - [Christ and depressions]. PMID- 6907530 TI - [Anorexia nervosa]. PMID- 6907527 TI - [Lack of leadership and administration. Critical observations on reorganization of continued education in nursing administration]. PMID- 6907531 TI - [Causes and therapy of liver cirrhosis]. PMID- 6907532 TI - [Time - devotion - affection: an initiative against deprivation in early childhood: "German League for the Child in the Family and the Community"]. PMID- 6907533 TI - In-service workshop on child abuse. PMID- 6907535 TI - Decision-making and the behavior gap. PMID- 6907536 TI - A community approach: school-based health care delivery. PMID- 6907534 TI - Hemophilia: the role of the school nurse. PMID- 6907537 TI - The research dilemma. PMID- 6907538 TI - Sex education in a rural high school. PMID- 6907540 TI - "All or None" evaluation: is it valid? PMID- 6907539 TI - Cooking as a learning experience. PMID- 6907541 TI - A health inventory for the school nurse. PMID- 6907543 TI - CPR certification in the classroom: it can be done! PMID- 6907542 TI - School health screening of Indochinese refugee children. PMID- 6907544 TI - Introducing nutrition education. AB - A significant increase in nutrition knowledge followed a short-term nutrition education series among junior high school students in two local schools. This increase in knowledge was measured by pretests and posttests and was determined to be statistically significant. Ideally, nutrition education should be instituted in early childhood rather than delaying until adolescence; but the educational process must begin somewhere regardless of income, cultural, social or economic practices or level of education. Until the process can be implemented at an early age, every opportunity must be taken to reach individuals. PMID- 6907545 TI - Mildly handicapped children in the mainstream--implications for the health educator. AB - The Education for All Handicapped Children Act of 1975, PL 94-142, will cause mildly handicapped children to be integrated into mainstream academic classes including health education. Because of the disparate needs of these children, health educators will have to provide for a diverse group of learners. Since it is clear that health education encompasses topics crucial to the overall social and personal development of the handicapped, it is essential that health educators become prepared to maximize learning opportunities for the handicapped child in the mainstream. PMID- 6907546 TI - An experiment in group adolescent weight loss guidance. PMID- 6907547 TI - Development of a preventive fire education program based on a profile of the hospitalized burn victim. PMID- 6907548 TI - Organization and evaluation of health fairs. AB - In summary, the success of a health fair as a source of health education and promoter of healthful behaviors depends to a great extent upon the organizational expertise of the sponsor and cooperating forces. However, even more essential is the stimulation of health fair visitors' interest and participation, the provision of information and health status feedback and the reinforcement of positive health values. The health fair which best achieves these objectives will have a greater likelihood of also attaining its original preventive health goals and objectives. Although evaluation articles tend to stress the positive findings, this review does not imply that every health fair is a success or that every successful health fair is without criticism. Long waiting lines, unexpected equipment malfunctions, inadequate hours for visiting, understaffed activities, limited floor space and/or visual distractions and noise disturbances may still occur despite the most thorough organizational efforts. This review has attempted to synthesize from the existing sources on health fairs those essential organizational and evaluative factors necessary for a health fair to maximize its potential health education impact. PMID- 6907549 TI - Institutionalizing peer education in the health education classroom. PMID- 6907550 TI - A birth defects prevention curriculum for inner-city junior high school students. PMID- 6907551 TI - [Continuity of medical care and significance of the written report on the patient at the time of discharge]. PMID- 6907552 TI - [The written report at discharge from the hospital and the nursing notes]. PMID- 6907553 TI - [Written report at discharge from the hospital as a nursing record]. PMID- 6907554 TI - [Written report at discharge from the hospital and evaluation of continuity of nursing--transfer from the hospital to ambulatory care and the regional public health clinic]. PMID- 6907555 TI - [Survey of needs of families of patients in the terminal stage of cancer]. PMID- 6907556 TI - [Human science. Sex (3). Depth of sexual psychology]. PMID- 6907557 TI - [Bedside conference on pediatric nursing: 12. Hematological disease (6), malignant tumor (4), collagen disease in children and nursing of an infant hospitalized for observation]. PMID- 6907559 TI - [Clinical training in education]. PMID- 6907558 TI - [Nursing system: a vision for future changes (2). National Commission for the Study of Nursing and Nursing Education]. PMID- 6907560 TI - [Curriculum evaluation: theory and practice: with a case study from nursing education]. PMID- 6907561 TI - [Planning clinical training with cooperation of the local health facilities--a study originated by students. 1]. PMID- 6907562 TI - [New problems concerning manpower allocation in a hospital. On allocation of nursing personnel for continued nursing]. PMID- 6907563 TI - [New problems concerning manpower allocation in a hospital. The ICU and the concept of allocation of nursing personnel]. PMID- 6907564 TI - [New problems concerning manpower allocation in a hospital. Changing features of nursing duties and problems of manpower allocation]. PMID- 6907565 TI - [New problems concerning manpower allocation in a hospital. The current status and trends in basic research in computation of necessary nursing personnel]. PMID- 6907566 TI - [New problems concerning manpower allocation in a hospital. Obstacles in the increase of nursing manpower]. PMID- 6907567 TI - [Development of team conference]. PMID- 6907569 TI - [Nursing system: a vision for future changes. 3]. PMID- 6907570 TI - [Bedside conference: planning of clinical training programs. The circulatory system (1) - evaluation of nursing needs during the recovery process]. PMID- 6907568 TI - [Human science. Sex. 4. Sexual and psychological maturity]. PMID- 6907572 TI - [Focal point in nursing education. (10). Problems in clinical training in nursing]. PMID- 6907571 TI - [The nurse, a person within the system. (1) Basic factors in the organization of the modern work system]. PMID- 6907573 TI - [Curriculum evaluation: theory and practice - with a case study from nursing education]. PMID- 6907574 TI - [Understanding of the needs of patients with poor prognosis - with special reference to patients with malignant disease of female reproductive organs]. PMID- 6907575 TI - [Planning of nursing activities for patients with poor prognosis - a case of a cancer patient who was aware of his condition]. PMID- 6907576 TI - [Approach to a mother of a child with poor prognosis (malignant meningioma)]. PMID- 6907577 TI - [Interactions with patients with poor prognosis and their families within a local public health jurisdiction]. PMID- 6907578 TI - [Study on anemia among female students - characteristics of anemic diathesis]. PMID- 6907580 TI - [Human science. Sex. (5) Common courtesy and sex in an illiterate society]. PMID- 6907581 TI - [Bedside conference: planning of clinical training. (2) The circulatory system (2) Nursing during recovery]. PMID- 6907579 TI - [A solution to the confusion in the problem of nursing planning]. PMID- 6907582 TI - [The nurse: a person within a system. (2) Problems of organizational problems in medicine]. PMID- 6907583 TI - [Focal points in nursing education (11). Education and evaluation]. PMID- 6907584 TI - [Research on clinical training: a study by Roper]. PMID- 6907585 TI - [Psychology of patients with poor prognosis and problems concerning nursing]. PMID- 6907587 TI - [Nursing process: nursing of patients with kidney failure. Diagnosis and treatment of kidney failure]. PMID- 6907588 TI - [In search of new nursing philosophy. IV. Sorrow of illness]. PMID- 6907589 TI - [Test yourself. Nursing of patients with lumbar disk herniation]. PMID- 6907586 TI - [Nursing process: nursing of patients with kidney failure. Physiopathology of kidney failure]. PMID- 6907590 TI - [Nursing process: nursing of patients with kidney failure. Nursing process for a patient with chronic kidney failure associated with adrenal insufficiency]. PMID- 6907591 TI - [Puncture: indication and methods]. PMID- 6907592 TI - [Basic nursing care associated with bone marrow puncture]. PMID- 6907593 TI - [Assistance of the patient during puncture]. PMID- 6907594 TI - [Nursing and therapy: radiotherapy. Indication and methods of radiotherapy (I)]. PMID- 6907595 TI - [Nursing and therapy: radiotherapy. Nursing of patients undergoing radiotherapy (1) - the concept of radiotherapy and nursing of patients undergoing external irradiation]. PMID- 6907596 TI - [Toward humane nursing. Assistance of the amputee and the nursing personnel - keypoints during the rehabilitation stage of the amputee who has attempted suicide]. PMID- 6907597 TI - [Nursing process: nursing of patients with apoplexy. Etiology and physiopathology of apoplexy]. PMID- 6907598 TI - [Nursing process: nursing of patients with apoplexy. Diagnosis and therapy of apoplexy]. PMID- 6907599 TI - [Nursing process: nursing of patients with apoplexy. Nursing process in the care of patients with apoplexy]. PMID- 6907600 TI - [Nursing process: nursing of patients with apoplexy. Discussion: on the problems in nursing planning]. PMID- 6907601 TI - [Nursing seminar: restraints. On the methods of restraints--with special reference to the classroom practice]. PMID- 6907602 TI - [Nursing seminar: restraints. Methods of restraints for children]. PMID- 6907603 TI - [Nursing seminar: restraints. On the problems of restraints in the psychiatric department]. PMID- 6907605 TI - [Nursing and therapy: radiotherapy. Nursing of patients receiving radiotherapy (2)--brachytherapy]. PMID- 6907604 TI - [Nursing and therapy: radiotherapy. Application and methods of radiotherapy (II)]. PMID- 6907606 TI - [Assistance for young paraplegic patients and the nursing personnel--with special reference to the psychological approach]. PMID- 6907608 TI - [Assistance for the mother who gave birth to a premature infant--motivation for sound mother-child relationship. (1)]. PMID- 6907607 TI - [New nursing philosophy. V. "Added luster to the light" as an analogy to nursing in medical therapy]. PMID- 6907609 TI - Night sleep of children in a hospital. Part I: sleep duration. PMID- 6907612 TI - The vulnerability of a primipara during the antepartal period. PMID- 6907610 TI - Cognitive and affective aspects of the responses of pregnant women to sonography. PMID- 6907611 TI - Extinction of pacifier and bottle behavior in a three-year-old child. PMID- 6907615 TI - From the executive director: shortages in nursing. PMID- 6907614 TI - [Penicillin-resistant Branhamella catarrhalis. Frequency and appropriate therapy]. PMID- 6907613 TI - Aging of connective tissue. AB - The purpose of this paper is to review and to illustrate some of the themes underlying recent research on the aging of connective tissues. The systematic variation with age of the relative rates of biosynthesis (and of degradation) of the macromolecules of the intercellular matrix (collagens, elastin, proteoglycans and structural glycoproteins) is interpreted as the result of an "age program" of matrix synthesis by differentiated mesenchymal cells. This relative rates of synthesis of a well-defined set of matrix macromolecules can be used in its turn to define the state of differentiation (and of aging) of mesenchymal cells. This relative rate of synthesis of a well-defined set of matrix macromole-followed by its degradation through the elastases. The increasing frequency of some diseases with age ("aging diseases" of connective tissues, athero-/arteriosclerosis, diabetes, osteoarticular diseases, etc.) is probably related to this changing composition of the intercellular matrix. Cell-matrix interaction does depend on the secretion of a specific matrix which in its turn influences cell behaviour. With changing matrix composition (changing cell environment) cell behaviour will also change. This informational feedback mechanism may be of great importance in the aging of connective tissues and also in the increasing frequency of some pathologies with age. PMID- 6907616 TI - Quality assurance. PMID- 6907617 TI - Barbara Blakeney addresses AHA hearing on nursing shortage. PMID- 6907618 TI - Janet Beirne 'spells it out' for AHA Commission on Nursing. PMID- 6907619 TI - [Role of the nurse anesthetist in cardiac anesthesiology]. PMID- 6907620 TI - [Complete transverse heart block]. PMID- 6907621 TI - [Anesthesia and the immediate postoperative period in young infants with congenital heart defects operated on under artificial circulation]. PMID- 6907622 TI - [Medical gymnastics and massage with children after heart operations]. PMID- 6907623 TI - [Physiotherapeutic treatment of patients with implanted cardiac pacemakers]. PMID- 6907624 TI - [Medical gymnastics after heart valve prosthesis]. PMID- 6907625 TI - [Use of bioprostheses for replacement of heart valves]. PMID- 6907626 TI - [Pressing problems of modern cardiac and vascular surgery]. PMID- 6907627 TI - [Asepsis and antisepsis in modern surgery]. PMID- 6907628 TI - [Principles of formulating balanced menus in preschool institutions]. PMID- 6907629 TI - [Information support for the paramedical workers of a city hospital]. PMID- 6907631 TI - [Vulvovaginitis in girls]. PMID- 6907630 TI - [Experience in raising the qualifications of nurses in Moscow tuberculosis institutions]. PMID- 6907632 TI - [Introduction of hygienic habits among the population]. PMID- 6907633 TI - [Principles of anesthesia in heart operations]. PMID- 6907634 TI - [Chronic glomerulonephritis]. PMID- 6907635 TI - [Acute pyelonephritis]. PMID- 6907636 TI - [Acute and chronic nonspecific cystitis]. PMID- 6907637 TI - [Closed injuries of the kidney, bladder and urethra]. PMID- 6907638 TI - [Hemodialysis in the treatment of kidney failure]. PMID- 6907639 TI - [Urine collection and study]. PMID- 6907640 TI - [Carbohydrates in the nutrition of the elderly]. PMID- 6907641 TI - [Rehabilitation of patients in older age groups who have had a stroke]. PMID- 6907643 TI - [Medical gymnastics in changes in the joints of the lower extremities in the elderly]. PMID- 6907642 TI - [Drug therapy principles in old age]. PMID- 6907644 TI - [Physio- and balneotherapy for diabetes mellitus patients]. PMID- 6907645 TI - [Hypocorticism]. PMID- 6907646 TI - [Complications in glucocorticoid treatment]. PMID- 6907648 TI - [Subcutaneous and intramuscular injections]. PMID- 6907647 TI - [Physiotherapy in hypertension]. PMID- 6907649 TI - [Role of the nurse in caring for the elderly]. PMID- 6907650 TI - [Characteristics of care for geriatric patients]. PMID- 6907651 TI - [Instruction and training of nurses in geriatrics]. PMID- 6907652 TI - [Drug plants with sedative and hypotensive action]. PMID- 6907654 TI - Guidelines: use of supplemental nursing services. PMID- 6907653 TI - [Kallikreins, proteases with multiple biological activity]. PMID- 6907655 TI - Nursing alive and well and closely glued together. PMID- 6907656 TI - Michigan Public Health Code: definitions of nursing. PMID- 6907657 TI - Emotional stages of dying. PMID- 6907659 TI - The Second Report from the Social Services Committee on perinatal and neonatal mortality. PMID- 6907658 TI - Direct entry method of training midwives in three countries: 1. The Netherlands. PMID- 6907660 TI - A preliminary report on the research project on the role and responsibilities of the midwife: Part 2. PMID- 6907661 TI - International views of breast feeding. PMID- 6907662 TI - A risky business. PMID- 6907663 TI - A preliminary report on the research project on the role and responsibilities of the midwife: Part 3. PMID- 6907665 TI - Mind over body. PMID- 6907664 TI - Direct entry method of training midwives in three countries: 2. Denmark. PMID- 6907666 TI - The care and safety of patients and staff in the operating department. PMID- 6907667 TI - The United Kingdom's contribution to Europe. PMID- 6907668 TI - Pondocillin--novel approach to ampicillin therapy. PMID- 6907669 TI - The road to a Fellowship Award (or "A Nurse's Tale"--not ascribed to Chaucer). PMID- 6907670 TI - An informed legislator can make a difference for nursing! PMID- 6907671 TI - Pitfalls of budgeting. PMID- 6907672 TI - Otosclerosis: its history and new hope for the otosclerotic. PMID- 6907673 TI - Education mobility of the associate degree and diploma students in the State of Nebraska. PMID- 6907674 TI - The patient's need to know. PMID- 6907675 TI - Continuous ambulatory peritoneal dialysis and the blind patient. PMID- 6907676 TI - Teaching and learning for self-care dialysis. PMID- 6907677 TI - Health technology and the role of the nurse in ESRD care. PMID- 6907679 TI - Adjustment and quality of patient-nurse interaction among dialysis patients. PMID- 6907678 TI - Dealing with an ethical dilemma: a case in application. PMID- 6907680 TI - Heparin usage in chronic hemodialysis. PMID- 6907681 TI - Psycho-social care for the home dialysand and partner. PMID- 6907682 TI - Facility report. Cleveland Clinic Foundation. PMID- 6907683 TI - Renal disease at a glance: diabetic nephropathy. PMID- 6907684 TI - Renal clinic modality. PMID- 6907685 TI - Establishing a CAPD program. I. The nurses' role in setting up the CAPD program. PMID- 6907686 TI - Establishing a CAPD program. PMID- 6907688 TI - Establishing a CAPD program. II. The CAPD patient teaching program. PMID- 6907687 TI - Legislative log: incentive reimbursement for outpatient dialysis and self-care dialysis training. PMID- 6907690 TI - Recognizing the communications disorder in dialysis dementia. PMID- 6907689 TI - Establishing a CAPD program. III. Nursing management in continuous ambulatory peritoneal dialysis. PMID- 6907691 TI - CAPD for the blind. PMID- 6907692 TI - Possible dialyzer hypersensitivity. PMID- 6907693 TI - The hemodialysis client: nursing focus on self-care. PMID- 6907694 TI - Vancomycin and the ESRD patient--a nursing focus. PMID- 6907695 TI - Always a nurse. PMID- 6907696 TI - Nursing is not a profession. PMID- 6907697 TI - The development of an evaluation process for technical level competency. PMID- 6907698 TI - Are PHN skills used in screening clinics? PMID- 6907699 TI - Supplemental agency nurses and hospital staff nurses: what are the differences? PMID- 6907700 TI - Evaluating home care? Compare viewpoints. PMID- 6907701 TI - Strengthen the nurse's role in nutritional counseling. PMID- 6907702 TI - "Supply-side" nursing. PMID- 6907703 TI - [Cycling and nutrition]. PMID- 6907705 TI - [Bladder catheterization and rectal palpation]. PMID- 6907704 TI - [Method of extracting a harpoon]. PMID- 6907706 TI - [Female circumcision and infibulation. Involuntary collaboration, through ignorance, in 6 cases of intra-hospital female circumcision, technics]. PMID- 6907707 TI - [The matron and sex education]. PMID- 6907708 TI - [Family planning]. PMID- 6907709 TI - [Contraceptive methods]. PMID- 6907710 TI - [Primary health care]. PMID- 6907712 TI - [Health facility of Tenerife. Confrontation between the Physicians' Council and nursing personnel. Need for nursing's direction with its own autonomy]. PMID- 6907711 TI - [Maternal-infant welfare]. PMID- 6907713 TI - [Conceptual framework for the matron]. PMID- 6907714 TI - [The concept of public health]. PMID- 6907715 TI - [Reasons for the accreditation with an examination and a course]. PMID- 6907716 TI - [Administration's role in a conflict]. PMID- 6907717 TI - [Aviation accident en Tenerife; the other side of the conflict]. PMID- 6907718 TI - [The health reorganization we hope for]. PMID- 6907719 TI - [1st Vice-president responsible for the field of Education and Planning of the Council. Interview with Ms. Francisca Benabent, 1st Vice-president]. PMID- 6907720 TI - [Fetal erythroblastosis]. PMID- 6907721 TI - [3 questions concerning the conflict]. PMID- 6907722 TI - [University School of Nursing: problems without solution]. PMID- 6907723 TI - [A continuing disillusion: nursing and the Ministry of Health]. PMID- 6907724 TI - [To the Assembly of Presidents of the Medical Council: the Technical Health Assistance are all right]. PMID- 6907725 TI - [To Spanish nursing which has removed the confining ceiling. Interview with Nelly Garzon, President of the National Nurses' Association of Colombia]. PMID- 6907727 TI - [Post-basic education]. PMID- 6907726 TI - [The Congress of the Cuban Nurses' Association]. PMID- 6907728 TI - [General information on the standardization course]. PMID- 6907729 TI - [Research in nursing: process which contributes to and promotes professional development]. PMID- 6907731 TI - [Activities of the International Council of Nurses]. PMID- 6907730 TI - [Nursing as a discipline]. PMID- 6907732 TI - [Winifred Logan, Executive Director of the I.C.N]. PMID- 6907733 TI - [Nursing process, a theoretical concept, an ideology, a reality]. PMID- 6907734 TI - [Cornella de Llobregat: health planning]. PMID- 6907735 TI - [The nursing professional is the worker in the first line of combat. Interview with Angela Garcia Moreno, General Director of Planning of the Health Advisory Body of the Council of the Canary Islands]. PMID- 6907736 TI - [Shaping history, shaping the profession]. PMID- 6907738 TI - [Health center project. The Mataro Health Committee]. PMID- 6907737 TI - [Health administration]. PMID- 6907739 TI - [Health education in the community: possible role of the Technical Health Assistant of the public health service]. PMID- 6907740 TI - [Health education in the school world]. PMID- 6907742 TI - [Family planning in primary health care]. PMID- 6907741 TI - [Maternal-infant care in primary care]. PMID- 6907743 TI - [The 100-to-300-bed hospital, teaching center for the nursing profession, integral member of the health team]. PMID- 6907744 TI - [Health reform: the President of the Council reports to the Delegates' Congress]. PMID- 6907747 TI - One the scene: Stanford University Hospital. Developing a patient classification system. PMID- 6907745 TI - The nurse's role and responsibility in corporate-level planning. PMID- 6907748 TI - On the scene: Stanford University Hospital. Developing nurse managers. PMID- 6907746 TI - One the scene: Stanford University Hospital. Job satisfaction survey: a tool for organizational change. PMID- 6907749 TI - On the scene: Stanford University Hospital. Claiming power: a strategy for change. PMID- 6907750 TI - On the scene: Stanford University Hospital. Resistance to change: primary nursing versus therapeutic community. PMID- 6907751 TI - On the scene: Stanford University Hospital. From inservice to educational services... PMID- 6907752 TI - On the scene: Stanford University Hospital. The changing role of the nurse in product evaluation. PMID- 6907753 TI - On the scene: Stanford University Hospital. Nursing Research in an acute care setting. PMID- 6907754 TI - One the scene: Stanford University Hospital. Changing work stress: use of nurse to-nurse consultation. PMID- 6907755 TI - On the scene: Stanford University Hospital. An innovative approach to a chronic recruitment problem. PMID- 6907756 TI - Using theory to promote change. PMID- 6907757 TI - Peer review: change and growth. PMID- 6907758 TI - NAQ forum: planning for change. PMID- 6907760 TI - Promoting change in nurse communication with cancer patients. PMID- 6907759 TI - One the scene: Stanford University Hospital. PMID- 6907761 TI - Faculty intervention into suicidal crisis. PMID- 6907763 TI - Determining faculty workload. PMID- 6907762 TI - Investigate before you educate. PMID- 6907764 TI - No more Mr. Nice Guy. Sharing. PMID- 6907765 TI - News makers. In practice. PMID- 6907766 TI - Pulmonary embolism: preventing it, treating it. PMID- 6907767 TI - Speaking to the needs of your aphasic patient. PMID- 6907769 TI - Charting: how to get out of a rut. PMID- 6907768 TI - How to spot...and care for...the patient with Lown-Ganong-Levine syndrome. PMID- 6907771 TI - Helping pregnant teenagers eat right. PMID- 6907772 TI - A short, simple tool for assessing your patient's pain. PMID- 6907770 TI - Ambulatory nursing: old enough to get pregnant...too young to have babies. PMID- 6907773 TI - Nursing grand rounds: postoperative complications. How to help the patient when everything goes wrong. PMID- 6907774 TI - Challenge: is there a cure for Kent? PMID- 6907775 TI - Test your knowledge of managing the patient with hypertension. PMID- 6907776 TI - Improving patient compliance with a self-medication teaching program. PMID- 6907778 TI - Medication errors: check before administering the last capsule in a container. PMID- 6907779 TI - Diagnostic tests: what to do when they call for inserting gastrointestinal tubes. PMID- 6907777 TI - Helping the ostomate return to normal life. PMID- 6907781 TI - Understanding ultrasonography. PMID- 6907782 TI - "Well" is just another way of feeling. PMID- 6907780 TI - Career guide: to change what needs changing...doesn't take Wonder Woman. PMID- 6907783 TI - Medication errors: check the name on the medication administration record before transcribing a drug order. PMID- 6907784 TI - Furosemide: a potent diuretic that requires careful patient monitoring. PMID- 6907785 TI - Three common gastrointestinal tests--and how to help your patient through each. PMID- 6907788 TI - Counseling the pregnant teenager. PMID- 6907787 TI - Usually benign, but always frightening--that's mitral valve prolapse. PMID- 6907786 TI - A guide to headaches--and how to relieve their pain. PMID- 6907789 TI - Taking the fear out of bone marrow examinations. PMID- 6907790 TI - If your patient's legs hurt, the reason may be arterial insufficiency. PMID- 6907791 TI - How to plan patient-oriented team conferences that will save you time. PMID- 6907792 TI - Test your knowledge of helping patients cope with C.O.P.D. PMID- 6907793 TI - The great stent mystery; can you solve it? PMID- 6907794 TI - Sharon wanted more than we could give. PMID- 6907797 TI - Ethical issues, nursing, and the health care system. PMID- 6907796 TI - Professional and personal stress: a survey. PMID- 6907795 TI - Hispanic leadership considerations in nursing. PMID- 6907798 TI - Mentorhood: a key to nursing leadership. PMID- 6907800 TI - Middle East health services. PMID- 6907799 TI - A different focus on the job. PMID- 6907801 TI - Nurses and the legality of abortion. PMID- 6907802 TI - Legal notes: confidentially in nursing. PMID- 6907803 TI - Changes at Rampton? PMID- 6907804 TI - Voice of the ward sister. PMID- 6907806 TI - Communicating .... not just a one-way process. PMID- 6907807 TI - The role of the assessor in nursing appointments. PMID- 6907805 TI - Durham area library service. PMID- 6907808 TI - Legal notes: notification of accidents. PMID- 6907809 TI - Ear syringing. PMID- 6907810 TI - Ergonomics: the mechanics of man. 2.--The physiology of work. PMID- 6907811 TI - The dole toll. PMID- 6907812 TI - Safety: accident reporting - a guide to the new regulations. PMID- 6907813 TI - Maths genius - is he a numberskull? PMID- 6907815 TI - Handling stress makes dollars and sense. PMID- 6907814 TI - Alcoholism in the workplace: differential diagnosis. PMID- 6907816 TI - Drugs and dosages: marketing drugs. PMID- 6907817 TI - Nursing roles in alcoholism: the employees' assistance program in a one-nurse setting. PMID- 6907818 TI - Know your generics. PMID- 6907819 TI - Medical-surgical nursing practice standards. Standard V: the plan for nursing care is implemented. PMID- 6907820 TI - Drug diversion - the legal aspect. PMID- 6907821 TI - Drug diversion- the addicted nurse. PMID- 6907822 TI - Health care - expensive but we're still not healthy. PMID- 6907823 TI - Task force on aging. PMID- 6907824 TI - [Relations with the blind and vision-impaired. I]. PMID- 6907825 TI - [Living a dignified life - assistance towards living a full life]. PMID- 6907826 TI - [Relations with the blind and the vision-impaired. II]. PMID- 6907829 TI - [Personnel release as a necessary tool in the industrialization of hospital functions]. PMID- 6907827 TI - [The sick infant and his parents in the hospital]. PMID- 6907828 TI - [Primary health services - recommendations by the ICN]. PMID- 6907831 TI - Helping young children cope with the physical examination. PMID- 6907830 TI - Screening for seizures. PMID- 6907832 TI - Faith development in children. PMID- 6907833 TI - Reye syndrome: clinical guidelines for practitioners in ambulatory care. PMID- 6907834 TI - Pediatric management problems: cerebral palsy. PMID- 6907835 TI - Coping with hospitalization: a study of school-age children. PMID- 6907836 TI - Intervention in the interaction of a mother and child with nonorganic failure to thrive. PMID- 6907837 TI - Pediatric drug information: effects of caffeine on pregnancy and lactation. PMID- 6907838 TI - President's message: PNP's role in our national health policy. PMID- 6907839 TI - Equitable pay; research and reality. PMID- 6907841 TI - Should the clinical nurse specialist be free of administrative responsibility? PMID- 6907840 TI - A teaching design: standards of practice as a basis for peer review. PMID- 6907842 TI - Learned helplessness: a phenomenon observed among the nursing staff of "city hospital". AB - An interesting phenomenon could be observed among the nursing staff on a unit in a large city hospital where I was employed. One might describe it as apathy, laziness, or uncaring, or one could define the situation as "learned helplessness." PMID- 6907843 TI - A consultation analysis of learned helplessness at "city hospital". AB - It is known variously as "reality shock," bureaucratic-professional conflict, institutionalization, and even oppression. Whatever one calls it, however, the phenomenon described and conceptualized as "learned helplessness" by nurse-author Karen Malcomson is a vexing, trying, and familiar one to any clinician who has attempted to bring about change in a complex institution. PMID- 6907844 TI - Localization of kallikrein-like activity along a single nephron in rabbits. AB - In order to investigate the presence of renal kallikrein, the localization of kallikrein-like proteolytic activity along a single nephron was determined in rabbits. Single nephrons were dissected into 8 segments under a microscope. Activity was fluorometrically measured with two different substrates (benzoyl-L arginine ethyl ester: BAEE and prolyl-phenylalanyl-arginine-methylcoumarin amide: MCA). Proteolytic activity could be detected in the early (S1), the middle (S2), and the terminal (S3) portions of the proximal tubule and in the granular portion of the distal tubule (DCTg). With MCA, the specific activity in S1, S2, S3 and DCTg was 0.77 +/- 0.08, 0.28 +/- 0.10, 0.13 +/- 0.05, and 0.27 +/- 0.05 pmoles/microgram/min, respectively. The activity in DCTg was inhibited by aprotinin but that in the proximal tubules was not inhibited. No activity was found in the glomerulus, the thick ascending limb of Henle's loop, the bright portion of the distal tubule, and the light portion of the cortical collecting tubule. The inhibition of the activity by aprotinin in DCTg suggests that intrarenal kallikrein could be localized only in DCTg. PMID- 6907846 TI - The role of the professional association. PMID- 6907845 TI - The nucleotide sequence of spinach chloroplast tryptophan transfer RNA. AB - Spinach chloroplast tRNATrp, purified by column chromatography and two dimensional gel electrophoresis, has been sequenced using in vitro labeling techniques. The sequence is : pG-C-G-C-U-C-U-U-A-G-U-U-C-A-G-U-U-C-Gm-G-D-A-G-A-A C-m2G-psi-G-G-G-psi-C-U-C-A-A*-A-A-C-C-C-G-A-U-G-N-C-G-U-A-G-G-T-psi-C-A-A-G-U-C C-U-A-C-A-G-A-G-C-G-U-G -C-C-AOH. Like the E. coli suppressor tRNA psu+UGA which translates both the opal terminator codon U-G-A and the tryptophan codon U-G-G, spinach chloroplast tRNATrp has C-C-A as an anticodon and contains an A-U pair in the D-stem. PMID- 6907847 TI - Will faculty practice make perfect? PMID- 6907848 TI - Disseminating the results of nursing research. PMID- 6907849 TI - A VNA-organized hospice volunteer program. PMID- 6907850 TI - Child psychiatric nursing option. PMID- 6907851 TI - Evaluating patient outcomes. AB - In this study, nurses effectively demonstrated that in addition to stating goals in observable outcomes, they could develop rating scales to measure a patient's progress toward goal attainment. An unexpected finding was that improvement in evaluation was accompanied by corresponding improvement in other components of the nursing process. For example, prior to the study period, nurses rarely listened to chest sounds or measured ventilatory volume to assess lung congestion, even though many had received training in physical assessment and a respirometer was available on the unit. During the study period, however, there was a flurry of auscultation and spirometric measurement activities for patients whose goals were to decrease lung congestion. When one such patient failed to progress as rapidly as the nurse anticipated, greater assistance was given to pulmonary physiotherapy and assistance with coughing. Although nursing has not given sufficient attention to the development of patient evaluation tools, recent legislation as well as consumers' demand for quality care are providing the impetus for developing such mechanisms in a scientific way. This fact may significantly contribute to refining clinical data for the objective evaluation of patient progress. Since most nurses receive some theoretical education in the evaluation process, the challenge may well be to provide nurses, in both educational and service settings, with practical experiences in developing and implementing evaluation techniques. PMID- 6907853 TI - Facilitating student grade appeal hearings. PMID- 6907852 TI - A community is... PMID- 6907854 TI - Debunking the dead end dogma. PMID- 6907856 TI - Territorial issues in an interdisciplinary experience. PMID- 6907855 TI - Philosophical foundations of baccalaureate nursing education. PMID- 6907858 TI - Sounding board. Accreditation: the tail that wags the dog? PMID- 6907857 TI - Nursing turnover: some causes and solutions. PMID- 6907859 TI - Nursing and tenure. PMID- 6907860 TI - Using staff preceptors in a senior experience. PMID- 6907861 TI - Teaching assessment of client functioning. PMID- 6907862 TI - Lessons not learned. PMID- 6907863 TI - Measuring moral judgment in nursing dilemmas. AB - Based on cognitive theory of moral development, this research investigated the difference between nurses' responses to general, hypothetical moral dilemmas and their responses to real-life nursing dilemmas. The purpose of the research was to: identify recurrent moral dilemmas experienced by staff nurses; develop an instrument (Nursing Dilemma Test [NDT]) to measure nurses' responses to nursing dilemmas and the importance given to moral issues and practical considerations; relate staff nurses' responses to nursing dilemmas in the NDT and responses to hypothetical moral dilemmas in the Defining Issues Test to two subject variables (level of nursing education and length of clinical nursing experience); and compare moral judgments, both hypothetical general and nursing specific, of five subject groups (N = 225): staff nurses with associate degrees (57) and baccalaureate degrees (85) in nursing, nurses with masters degrees in nursing (10), college junior prenurses (36), and graduate level nonnurses (37). Findings verified the significance of formal education and previous involvement with similar dilemmas in enhancing principled thinking and raised questions about the relative strength of practical considerations in the hospital milieu. PMID- 6907864 TI - Predicting nurses' charting behavior based on Fishbein's model. AB - This study tested a theoretical model of behavior prediction within a quality assurance framework. Fishbein's mathematical model and the ANA quality assurance model were used to study nurses' charting behavior, based on selected attitudes, norms, and motivation levels. The sample consisted of nurses employed on a postcoronary care unit in a general, private hospital. Although significant findings were not obtained and the null hypotheses were not rejected, this study provided insight into nurses' attitudes, motivations, and behavior with regard to specific QA activities in a clinical setting. PMID- 6907865 TI - Methodological considerations in using videotape to establish rater reliability. PMID- 6907866 TI - A theoretical framework for nursing research in child abuse and neglect. AB - Three existing models for studying child abuse and neglect are evaluated and a theoretical framework with 10 assumptions about parent-child transactions in abusive or neglectful families are presented. PMID- 6907869 TI - Self-esteem changes in hospitalized school-age children. AB - This study compared changes in self-esteem in three groups of late school-age children (ages 9 through 12 years): those undergoing surgery (26 subjects), those hospitalized for nonsurgical reasons (25 subjects), and those not hospitalized (28 subjects). The children responded to the Coopersmith Self-Esteem Inventory which is designed to measure self-esteem derived from four sources--self, peer/social, school, and home/family--on two occasions with a one-month interval between responses. The hypothesis was tested using a one-factor analysis of variance, with change scores (final score minus initial score) as criterion measures. The hypothesis was supported; total self-esteem scores of surgical children dropped more than scores of nonsurgical and nonhospitalized children. Differences were found for the subscales of peer/social and school derivatives of self-esteem. Peer/social subscale scores of the surgical children dropped more than those of the other groups, and school subscale scores of surgical and nonsurgical children dropped more than the scores of nonhospitalized children. PMID- 6907868 TI - Enhancing reciprocity between mother and neonate. AB - Thirty mothers of newborn infants were assigned to one of three equal-sized treatment groups to assess the effects on maternal responsiveness of an early intervention designed to familiarize mothers with the capabilities and individual characteristics of their infants. Mothers in one treatment group observed the administration of the Brazelton Neonatal Behavior Assessment Scale to their infants, were given an explanation of each item on the scale, and were told their infants' responses. Mothers in a second group were given the same individualized explanations about the scale items and their infants' responses, but did not observe the events. A third group of mothers, which served as control group, received individual instruction on infant furnishings. Maternal responsiveness was enhanced significantly in the "show-and-tell" group but not in the "tell only" group. Parallel effects on infant responsiveness were also observed. ' PMID- 6907867 TI - Self-reported climacteric symptoms as a function of the relationships between marital adjustment and childrearing stage. AB - The relationship between reported climacteric complaints of 185 healthy middle class women between 40 and 60 years of age and marital adjustment and stages of childrearing were studied. Women low on marital adjustment had significantly more frequent and severe symptoms than women high on marital adjustment, but no differences in climacteric symptoms were reported for stage of childrearing or for the interaction between marital adjustment and stage of childrearing. Physical and psychosocial factors that may be related to the symptoms should be assessed before intervention strategies for midlife complaints are begun. PMID- 6907870 TI - Critical thinking, educational preparation, and development of moral judgment among selected groups of practicing nurses. AB - The focus of this descriptive study was the relationship between critical thinking, educational preparation, and level of moral judgment in 79 practicing nurses. The Watson-Glaser Critical Thinking Appraisal Test was used to measure critical thinking; information on the participating nurses' educational preparation was obtained from a personal information sheet. Moral judgment was measured by Rest's Defining Issues Test. The hypothesis that critical thinking would be positively related to moral judgment was tested by Pearson product moment correlation; the obtained coefficient of .5326 was significant at the .001 level. The hypothesis that there would be a difference between professional and technical nurses' moral judgments was tested through a one-way analysis of variance. The F ratio (F [1,77] = 9.6) was significant beyond the .01 level. Data also supported the hypothesis that critical thinking and educational preparation would predict greater variance in moral judgment than either variable alone, which was tested through multiple regression analysis (F [2,75] = 18.3, p = .01). Critical thinking and education together accounted for 32.9 percent of the variance in moral judgment. Implications of the findings are discussed for nursing research, practice, and education. PMID- 6907872 TI - Spotlight on children. Association of British Paediatric Nurses. PMID- 6907871 TI - Spotlight on children. The Bristol and South West Children's Heart Circle. PMID- 6907873 TI - Spotlight on children. Going into action. PMID- 6907874 TI - Spotlight on children. From university student to paediatric nurse. PMID- 6907875 TI - Spotlight on children. Diaphragmatic hernia. PMID- 6907876 TI - Spotlight on children. First impressions. PMID- 6907877 TI - Systems of life No. 75. Systems and signs: digestive system--1. PMID- 6907879 TI - Supervision of dissertations of undergraduate nursing students. PMID- 6907880 TI - Children and their parents in hospital. PMID- 6907881 TI - Pay '81: what are the prospects? PMID- 6907878 TI - Spotlight on children. Faith. PMID- 6907882 TI - Getting away from it all. Holiday for dialysis patients and their families. PMID- 6907883 TI - A psychiatric sister's ABC--1. PMID- 6907884 TI - Restructuring the NHS. The story so far. PMID- 6907885 TI - When is a nurse a management cost? PMID- 6907886 TI - Intensive and coronary care units. PMID- 6907887 TI - Stepping-stone to home. Self-care flatlets for geriatric patients. PMID- 6907889 TI - Heads first. The day we had an outburst from an unexpected quarter. PMID- 6907888 TI - A question of mind over matter? 1: a study of the psychological problems of patients with brain tumours. PMID- 6907890 TI - Going private. PMID- 6907891 TI - Getting it taped. PMID- 6907892 TI - Talking points no. 7. Dressed? You don't need to get dressed. PMID- 6907893 TI - Vegetarianism--an alternative diet or a crazy fad? PMID- 6907894 TI - Nursing care study: open lung biopsy and subsequent treatment. PMID- 6907895 TI - The care of the ward community. PMID- 6907896 TI - A question of mind over matter? 2: The response of the nurse using counselling skills. PMID- 6907898 TI - A psychiatric sister's ABC--2. PMID- 6907897 TI - Multiple sclerosis--2. PMID- 6907899 TI - Child health and local authority liaison nursing advice in the restructured health service. PMID- 6907901 TI - Pressure sores: pathogenesis, prophylaxis and treatment. 3. Medical Management and surgical intervention. PMID- 6907900 TI - Moulding the character. PMID- 6907902 TI - Elderly women's opinions about the benefits of health visitor visits. PMID- 6907903 TI - Elderly clients and withdrawal of night hypnotics. PMID- 6907905 TI - Where does all the money go? PMID- 6907904 TI - Recruiting for private hospitals. Interview by Cherril Hicks. PMID- 6907906 TI - They're gonna put me in the movies. PMID- 6907907 TI - The right information. PMID- 6907908 TI - Talking points no. 8. would you mind if we stood you up? PMID- 6907909 TI - Intravenous technology and the nurse. PMID- 6907911 TI - Nursing care study: rearing a premature infant in the Third World. PMID- 6907910 TI - The care of intravenous solutions. PMID- 6907912 TI - Team up to control infection. PMID- 6907913 TI - A psychiatric sister's ABC--3. PMID- 6907914 TI - Living and working in the USA. PMID- 6907915 TI - Letter from America. PMID- 6907916 TI - Geriatric patients and nurse learners' attitudes--1. PMID- 6907917 TI - The nurse and the patient. Communication skills. Non-verbal communication. PMID- 6907918 TI - TV documentaries: "Special hospital". Open to question. PMID- 6907919 TI - Uncle Sam's shopwindow. PMID- 6907920 TI - Health visiting in the 80's. PMID- 6907921 TI - The real needs of our growing population of elderly people. It all depends... PMID- 6907922 TI - Within our reach. Improvised dance. PMID- 6907924 TI - A psychiatric sister's ABC--4. PMID- 6907923 TI - Community nursing care study. Dying at home with dignity. PMID- 6907925 TI - The bridgebuilders: guide--3. Getting through without words. PMID- 6907926 TI - Communication skills. Talking points no. 9. You will be nil by mouth for a little while. PMID- 6907928 TI - Budget management in baccalaureate nursing programmes. PMID- 6907927 TI - Control of the nursing budget. The development of a new system. PMID- 6907929 TI - Community units of management in the restructured health service. PMID- 6907930 TI - Transfer of health information in cases of adoption. PMID- 6907931 TI - The duties of a health visitor. PMID- 6907932 TI - Pressure sores: pathogenesis, prophylaxis and treatments. 2. Predisposing factors: the 'at-risk' patient. PMID- 6907933 TI - The role and function of the registered nurse--1. PMID- 6907934 TI - CHCs are here to stay. PMID- 6907935 TI - A question of privilege. PMID- 6907936 TI - The shop window. PMID- 6907937 TI - Talking points. No. 4. If I'm not here in the morning. PMID- 6907938 TI - 'Quick, Nurse, give me some more water'! PMID- 6907940 TI - After the mastectomy: prostheses and clothing. PMID- 6907939 TI - The present and future roles of the anaesthetic nurse. PMID- 6907941 TI - Do-it-yourself medicine--2. PMID- 6907942 TI - The genetics of cancer--3. PMID- 6907943 TI - Aye, there's the rub. Communication skills. PMID- 6907944 TI - Extending the role of the clinical nurse specialist. PMID- 6907945 TI - The nurse and the patient. Communication skills. PMID- 6907947 TI - The journal of infection control nursing. PMID- 6907946 TI - The role and function of the registered nurse--2. PMID- 6907948 TI - The journal of infection control nursing. The biology, importance and control of pharaoh's ant (Monomorium pharaonis L.) infestations in hospitals. PMID- 6907949 TI - Postoperative wound sepsis. An infection control sister's approach. PMID- 6907950 TI - Candida in the mouth. PMID- 6907951 TI - Birth of a district. PMID- 6907953 TI - When is service not continuous? PMID- 6907952 TI - Legal semantics. Nurses and non-surgical abortions. PMID- 6907954 TI - Woe! Woe! Woe! PMID- 6907955 TI - The bridgebuilders' guide--2. What's in a word? PMID- 6907956 TI - Nursing care study: transient erythroblastopenia of childhood. PMID- 6907957 TI - A behavioural approach to psychiatric rehabilitation. PMID- 6907958 TI - Do-it-yourself medicine--3. PMID- 6907959 TI - Continuous assessment as effective industrial practice. PMID- 6907960 TI - A comparative study of nursing in Scottish and Danish prisons. PMID- 6907961 TI - Communication skills. Talking points no. 5. I want to go to bed. PMID- 6907962 TI - Fitting images. PMID- 6907963 TI - My long road to registration. PMID- 6907964 TI - Indigenous treatment of eye-complications: as reported by the villagers of a rural area. PMID- 6907965 TI - Research orientations in nursing--XX. Help! Where's the programme? The use of hand calculators and computer services. PMID- 6907966 TI - Report on the first phase of the project on primary health care. PMID- 6907967 TI - Prevention of sepsis in hospital wards and departments. PMID- 6907968 TI - Basal metabolic rate. PMID- 6907970 TI - Hardware on the ward. PMID- 6907969 TI - Nurse and aide: a nursing assistant's point of view. PMID- 6907971 TI - Innovations 7 - Intravenous chemotherapy: defeating the fear of the needle. PMID- 6907972 TI - Communication. 1. Getting the message across. PMID- 6907973 TI - Diploma in nursing: psychology, physiology. PMID- 6907974 TI - Alcoholism: a distinctive disease? PMID- 6907976 TI - Virology. 1. Agents of infection. PMID- 6907977 TI - Nursing care study. Subacute sclerosing panencephalitis: what's the matter with Norma? PMID- 6907975 TI - Adriamycin-induced alopecia: preventing fall-out. PMID- 6907978 TI - Care in action. PMID- 6907979 TI - CHCs: less bark and no bite? PMID- 6907981 TI - Innovations. 8. Psychosocial nursing: in search of reality. PMID- 6907980 TI - What's in a name? PMID- 6907982 TI - Communication. 2. Got the message? PMID- 6907983 TI - Park Hospital maternity unit: home sweet hospital. PMID- 6907984 TI - Park Hospital maternity unit: out of the ordinary. PMID- 6907985 TI - Management - wastage: in need of tender loving care. PMID- 6907987 TI - Virology. 2. Quality control. PMID- 6907986 TI - Post-cardiotomy delirium: windmills of your mind. PMID- 6907988 TI - Nursing care study. Personality disorder: labelled for life? PMID- 6907989 TI - Who cares about drug addicts? PMID- 6907990 TI - Radiotherapy. PMID- 6907991 TI - Radiotherapy: a focus on the Royal Marsden. PMID- 6907992 TI - Radiotherapy: gynaecological malignancies. PMID- 6907993 TI - Time for a change (again!). PMID- 6907994 TI - Cracking the colour bar. PMID- 6907995 TI - Communication. 3. Taking the simple route. PMID- 6907996 TI - Diploma in nursing: cause and effect of disease. Specialty. PMID- 6907997 TI - Why nursing is so special. PMID- 6907998 TI - So, what have you got to lose? PMID- 6908001 TI - Bromocriptine and endocrine imbalance. PMID- 6907999 TI - Veterinary diseases and man: rabies. PMID- 6908000 TI - Nursing care study. Diabetes mellitus: goodbye to all that. PMID- 6908002 TI - War games? PMID- 6908003 TI - Young--but with wrinkles. PMID- 6908004 TI - Psychiatry. 1. Two fistfuls of porridge. PMID- 6908005 TI - Pakistan diary: that was the week that was. PMID- 6908006 TI - A year ago this week. PMID- 6908008 TI - The nurse's role in the prevention of food poisoning. 1. Eat, drink and be healthy... PMID- 6908007 TI - Communication. 4. On a personal level. PMID- 6908009 TI - Nursing care study. Circumcision: big cut for a little boy. PMID- 6908010 TI - Wessex Regional Health Authority. October 1: a foolish decision? PMID- 6908011 TI - The work we have chosen and accepted. PMID- 6908012 TI - Is there sex after death? PMID- 6908013 TI - Smoking questionnaire. Warning: nursing can damage your health. PMID- 6908014 TI - Psychiatry. 2. A shock to the system. PMID- 6908016 TI - Diploma in nursing. Part B. Specialty. PMID- 6908015 TI - Nursing in Asia. 1. Going against the grain. PMID- 6908017 TI - The nurse's role in the prevention of food poisoning. 2. Now wash your hands please. PMID- 6908018 TI - Resident care plan: practising what is preached. PMID- 6908019 TI - Colostomy: changing the body's image. PMID- 6908021 TI - Going, going ... gone? PMID- 6908020 TI - Nursing care study. Gynaecology: piercing pains. PMID- 6908022 TI - Feeling the pressure yet? PMID- 6908023 TI - A luxury worth fighting for. PMID- 6908025 TI - Nursing in Asia. 2. Woman's realm. PMID- 6908024 TI - District nurse training. 1. Practice makes perfect. PMID- 6908026 TI - Psychiatry. 3. Knifing the soul. PMID- 6908027 TI - Standards of nursing care: quo vadis? PMID- 6908028 TI - Professing self control. PMID- 6908029 TI - Ingrowing toenails: nailing the problem. PMID- 6908030 TI - Behaviour therapy: sanction busting. PMID- 6908031 TI - Computerised tomography: all in a day's work. PMID- 6908033 TI - Voluntary Service Overseas: volunteering to care. Interview by Catherine Sadler. PMID- 6908032 TI - Nursing care study. Neuroblastoma: Darren's story. PMID- 6908034 TI - New units for the new NHS (2). PMID- 6908036 TI - Health and safety 5. Protection is better than Curie. The Nurses Action Group. PMID- 6908035 TI - Innovations 5. Community liaison nursing. Life beyond the hospital. PMID- 6908037 TI - Superannuation. 1. Towards retirement. PMID- 6908038 TI - The use of steroids in carcinomatosis. PMID- 6908039 TI - A chance for change. Interview by Andrew Brown. PMID- 6908040 TI - Echocardiography: sounding out the heart. PMID- 6908041 TI - Nursing care study. Endogenous depression: moody blues. PMID- 6908042 TI - Where angels fear to tread. Interview by Andrew Brown. PMID- 6908043 TI - Waiting, worry and the cancer experience. PMID- 6908044 TI - A hospice model and self-care theory. PMID- 6908045 TI - Patient education. PMID- 6908046 TI - Patient education. I. Why patient education? PMID- 6908047 TI - Patient education. II. Organizing for patient education: a nurse clinician's perspective. PMID- 6908048 TI - Patient education. III. The health educator's role in patient education: complement or conflict? PMID- 6908049 TI - Patient education. IV. Evaluating patient education programs. PMID- 6908050 TI - Teaching plan for patient undergoing total pelvic exenteration. PMID- 6908051 TI - In support of staff nurses. PMID- 6908052 TI - The nurse as expert witness. PMID- 6908053 TI - What to know before you testify in court. PMID- 6908054 TI - Dealing with controversy, Part I: Nursing Grows up. PMID- 6908056 TI - Transition from school to practice. PMID- 6908055 TI - What is "Entry into practice". PMID- 6908057 TI - The kallikrein-kinin system, renal function and hypertensive diseases. AB - The possibility that kallikrein and kinins play an important part in kidney function is strengthened by data that localized and characterized system components, described their pharmacologic effects and responses to various drugs and maneuvers, and discovered system abnormalities in hypertensive and renal diseases. The available data support the contention that further investigation will lead to important insights into the contribution the kallikrein-kinin system makes to normal kidney function. PMID- 6908058 TI - The nurse in the BLISS program. PMID- 6908060 TI - The role of nursing in primary health care. PMID- 6908059 TI - The new R.N. licensing examination in the United States: its implications to foreign nurse graduates. PMID- 6908061 TI - The clinical instructor: a vital catalyst. PMID- 6908062 TI - Stimulating teacher behavior. PMID- 6908063 TI - Search for the authentic self. PMID- 6908064 TI - Broadening employment opportunities for nurses. PMID- 6908065 TI - On the smoking issue: two views--I. Smoking: a professional matter. II. A plague from the West. PMID- 6908066 TI - The rural health practice program evaluated. PMID- 6908067 TI - Conceptual framework: students's conceptualization and interpretation. PMID- 6908068 TI - [Situation in practice]. PMID- 6908070 TI - [Sterilization and storage of sterilizing and sterile equipment]. PMID- 6908069 TI - [Professional evaluation and self-evaluation]. PMID- 6908071 TI - [After myocardial infarct]. PMID- 6908072 TI - [Nursing as a science]. PMID- 6908074 TI - [Graduate nurse]. PMID- 6908073 TI - [Personality and motivation in practice]. PMID- 6908075 TI - [A success story]. PMID- 6908076 TI - [We shall lead the way in our profession]. PMID- 6908077 TI - [Our work day in Cambodia]. PMID- 6908078 TI - [Spa treatment of arteriosclerosis]. PMID- 6908079 TI - [Catheterization of the bladder]. PMID- 6908081 TI - [Head nurse and nursing staff]. PMID- 6908080 TI - [Nursing functions]. PMID- 6908083 TI - Identifying the depressed patient. PMID- 6908082 TI - Problems with medicines. PMID- 6908084 TI - Essentials of geriatric care. AB - The geriatric patient presents a challenge to the primary care provider. Negative attitudes and stereotypes that have been imposed by society are a major block to the successful care of the elderly and need to be examined and changed. The teaching of geriatrics in medical and nursing schools and schools for health related professions may prevent some of these negative attitudes in the future. The elderly often present with many problems, which are the result of physical changes and multiple losses. These problems are physical, emotional, social, and spiritual. The possibility for resolution of each of these needs should be investigated using a holistic, multidisciplinary team approach, with no need being dismissed simply because of the patient's age. Interventions are directed toward assisting the elderly patient to achieve self-actualization or self fulfillment and attain and maintain the highest possible level of health, functioning, and quality of life. The physiologic changes that occur with aging result in a deviation from normal in the presentation and progression of disease, in the effects of medications, and in laboratory test results. There are alternatives to institutionalization, and these should be actively sought utilizing community supports. When institutionalization is chosen, rehabilitation should be the goal, if at all possible. Availability and therapeutic listening on the part of the primary care provider are invaluable. More time, energy, and giving of self are needed in order to successfully provide care to the geriatric patient; the challenge is great but the rewards are also great. The elderly are a wise, warm, and wonderful people. PMID- 6908085 TI - Ethics and medical decision-making. AB - There is a tendency for physicians to approach ethical problems in a manner similar to that in which they approach medical problems. Instead of disease categories (such as congestive heart failure or diarrhea), the physician substitutes moral quandaries (such as euthanasia or abortion). The goal is to learn what the "right" rules are for this particular problem at this particular moment. Although this method has important practical and instructive value, it can produce an empirical attitude toward ethics akin to that found in students who strive to learn medicine solely by algorithms. Using theoretical models as a center for discussion, this article has attempted to approach medical ethics as a decision-making process derived from the physician-patient relationship model in use. What is the type of physician-patient relationship that forms the soundest base for making ethical decisions? It must be realized that the contractual relationship cannot be ignored, for in our consumer-oriented society it will surely remain as a protection for the patient against the incompetent or immoral physician. It should not become the sole guide of physician behavior, however, lest we be satisfied with mediocre behavior as the maximal standard. Likewise, although technical competence is required for one to make the right and good decision, it is insufficient alone as a guide for moral behavior. Given the medically correct facts, a multitude of responses are available which necessitate a moral choice. Physicians need a guiding principle that goes beyond any aesthetic code of behavior, or protection of self-interest, and which enables them to deal with all the unexpected ethical questions faced in providing care to patients. Moral principles such as truth-telling, promise-keeping, and protecting the patient when he is vulnerable, help the physician to act in a moral manner, but lack the encompassing nature of the covenantal promise. The covenantal model includes a donative element that empowers the physician to go beyond any specific prescriptions of behavior in repayment of his gifted position. It inspires fidelity to the patient and the profession and respect for the patient's rights as an individual without either falling prey to the presumptuous attitude of the parental model or the legalistic tone of the contractual model. PMID- 6908086 TI - The dogged physical examination in the era of the C.A.T. AB - In attempting to evaluate the usefulness of the screening physical examination, it is necessary to remember that these recommendations are for asymptomatic individuals. When specific symptoms are present they need to be evaluated using physical examination and laboratory techniques that are appropriate to diagnosis. Although some of the same examination techniques are applicable for diagnostic evaluation, the goals, techniques, and interpretation of results are frequently different. One must also be aware of the past history of the patient, which may suggest specific risk factors even in the absence of current symptoms. A past history of breast cancer, for instance, might increase the intensity and scope of the physical examination. A history of alcohol consumption might turn an optimal mouth and throat examination into a diligent search. Additional elements of the physical examination may be pertinent to special high-risk groups. For instance, a mental status examination might be part of the routine examination for the elderly. Finally, it is important to remember that the findings on routine physical examination may themselves alter what should be done during the rest of the examination. For example, the finding of high blood pressure requires a search for arterial narrowing, coarctation, and renal bruits. Positive findings on a screening physical examination must always be supplemented by physical examination techniques designed for specific diagnosis. The recommended elements for a screening physical examination are an attempt to assemble reasonable conclusions based on current clinical use. They do not deal with the question of how frequently routine screening should be done. These recommendations need to be adjusted to the needs and views of each individual physician. One cannot help but be impressed by the medical, social, economic, and technical advantages of the physical examination. Although not a perfect technology, it serves important clinical functions in diagnosis and screening for the 1980s. The physical examination, like the human memory, will not be displaced easily even in this era of the C.A.T. scan, the radioimmunoassay, or the nuclear angiogram. PMID- 6908087 TI - Immunizations for adults and children. PMID- 6908088 TI - The interpretation of laboratory tests. PMID- 6908090 TI - "Nothing more to do". PMID- 6908089 TI - Evaluating medical research. PMID- 6908092 TI - Nurses qualify as expert witnesses. Case in point: Page v. Wilson et als (272 S.E.2d 8 - N.C.). PMID- 6908091 TI - Emergency nursing and professional judgement. PMID- 6908094 TI - Mental patients and forced-medication. Case in point: Rogers et al v. Okin, M.D. et al (634 F 2d 650 - MASS.). PMID- 6908093 TI - Legal case briefs for nurses. TX: Bedfall: family lowered bed rails. N.Y.: O2 and N.O. mixed: R.N., others, cleared. PMID- 6908095 TI - Catheter management programs and postoperative urinary dysfunction. AB - This study was designed to compare the effectiveness of two approaches to urinary catheter management in controlling postoperative urinary dysfunction in 110 patients following abdominoperineal resection or low anterior bowel resection. Patients, stratified by sex and surgical procedure, were randomly assigned to either straight gravity drainage or a 6-day progressive catheter clamping program. The bladder training program following abdominoperineal resection reduced significantly the urinary dysfunction rate in women but not in men. Marked differences in dysfunction rates were related to type of surgery, gender, and surgeon. Etiology of postoperative voiding dysfunction in various groups is discussed. PMID- 6908096 TI - Patient-centered variables in primary and team nursing. AB - Patient-centered variables and their relationship to primary and team nursing have rarely been studied. In the present study the investigation focused on the following patient-centered variables: nurturance received, patient involvement, and frequency of nurse-patient contacts. Baseline observational data were collected on 12 adult medical patients experiencing team nursing care. A primary nursing care approach was then implemented on the same nursing unit, and 6 months later 12 patients were observed under this system. Patients were directly observed 24 hours a day for 5 days of hospitalization and audiotaped, using a specimen record method. This method produced transcripts that were coded for nurturance, involvement, and nurse-patient contacts. Results of the study showed that there were no differences between primary and team nursing care groups in the number of contacts, nurturance, or patient involvement with all nursing personnel or with professional nurses. However, when the primary group was adjusted to include only those patients for whom primary nursing care was fully implemented, the primary group received more nurturance (p less than .05) and had a tendency to be more active involved than did the team group (p less than .10). These findings indicate that the institution of primary nursing care is related to increased quality of nursing care. PMID- 6908097 TI - Father to infant attachment: effects of early contact and characteristics of the infant. AB - Fifty-one father-infant dyads were studied at 24-72 hours of age and at 1 month to determine the effects of early contact, sex, and irritability of the infant on fathers' perceptions and behaviors. Irritability was measured by a factor of four items from the Brazelton Neonatal Assessment Scale administered at 24-72 hours. Fathers who held their infants in the first hour of life demonstrated more nonverbal behavior toward their infants during on observation at 1 month than those who did not have this early contact. Fathers interacted more verbally with girls than with boys at 1 month. A sex and irritability interaction effect was found in fathers' perception of high-irritability boys and low-irritability girls. Fathers also reported more frequent care-taking of high-irritability infants of both sexes than of low-irritability infants. PMID- 6908099 TI - [Rights of hospital patients]. PMID- 6908098 TI - Influencing adherence among hypertensives. AB - In the treatment of hypertension, problems of nonadherence and consequent poor blood pressure control are particularly severe. Alternative intervention strategies were compared to explore means of improving adherence and lowering blood pressures. In a 3 x 4 repeated measures analysis of variance design, 115 patients were randomly selected and randomly assigned to one of three treatment modalities (routine clinic care, patient education, and contingency contracting) and were followed over four clinic visits. Subjects' knowledge about hypertension and its management, adherence to requests for regular medical follow-up, and blood pressure levels were measured. Patient education was not effective in lowering blood pressures; it produced an untoward outcome, a dropout rate higher than that for patients receiving only routine clinic care. However, contingency contracting was an effective intervention strategy for improving patient knowledge, F (1,59) = 51.32, p less than .0001; adherence to requests for regular medical care, Max L (2) = 25.9, p less than .0001; and decreasing diastolic blood pressures, F (2,49) = 3.39, p less than .05. PMID- 6908100 TI - [In Europe: a program for the development of nursing care]. PMID- 6908101 TI - [In Germany (FRG): the organization of hospital nursing services]. PMID- 6908102 TI - [In Belgium: home care services organization]. PMID- 6908103 TI - [In Denmark: with a nurse of PMI]. PMID- 6908104 TI - [In Denmark: Bystaevneparken, the city of "Elderly People"]. PMID- 6908105 TI - [In Spain: the nursing profession]. PMID- 6908106 TI - [In Great Britain: in a great industrial enterprise]. PMID- 6908107 TI - [In the Netherlands: school health services start before school]. PMID- 6908108 TI - [In Switzerland: care of the elderly patient: a renewed professional role]. PMID- 6908109 TI - [Broncho-pulmonary cancers]. PMID- 6908110 TI - [Those patients with lung cancer]. PMID- 6908111 TI - [Architecture and pedagogy]. PMID- 6908112 TI - [Care of natural cavities]. PMID- 6908113 TI - [Common problems in preschool children. I. Hygiene of the young child: questions raised by the normal development of children]. PMID- 6908114 TI - [Multiple wounds: management in the emergency department and immediately thereafter]. PMID- 6908115 TI - [Digestive hemorrhages]. PMID- 6908116 TI - [Heart catheterization: purpose, indications, technic, results. Comparison with other methods]. PMID- 6908117 TI - [Social Security. 2. General regulations: health insurance]. PMID- 6908118 TI - [The nurse and the aphasic patient or nonverbal communication]. PMID- 6908120 TI - [Prolonged fever]. PMID- 6908119 TI - [Home care for the laryngectomized patient]. PMID- 6908121 TI - [The role of the nurse as being considered by the Ministry of Health]. PMID- 6908122 TI - Sex Q and A. Frank answers to your most delicate patient-counseling questions. PMID- 6908123 TI - Keeping cool in a code. PMID- 6908124 TI - Code drugs in brief. PMID- 6908125 TI - I tried hypnosis instead of anesthesia and never felt a thing. PMID- 6908127 TI - Opinion exchange: is it safe to give "friendly advice"? PMID- 6908126 TI - Toward impeccable IV technique. Those all too common IV complications...and the simple steps you can take to avoid them. PMID- 6908128 TI - Parenteral antibiotics: the hazards to watch for. PMID- 6908129 TI - IV and IM antibiotics: when giving. PMID- 6908130 TI - Look alike lesions. PMID- 6908131 TI - 27 reasons people don't take their meds...and what you can do about it. PMID- 6908132 TI - Eye and ear cultures. Tips on taking these simple, yet important, specimens. PMID- 6908133 TI - A troubleshooter's guide to indwelling catheters. PMID- 6908134 TI - Part six. Cancer chemotherapy. Those dreaded side effects and what to do about them. PMID- 6908135 TI - The right first aid for poisoning. PMID- 6908136 TI - Legally speaking. Let the visitor beware! PMID- 6908137 TI - Advice of counsel. Controlling non-prescription drug risks. PMID- 6908138 TI - Sound off! So you say you're a professional? PMID- 6908139 TI - A cavalcade of new drugs. PMID- 6908140 TI - Sex Q & A. Frank answers to your most delicate patient-counseling questions. PMID- 6908141 TI - Urgent priorities in severe trauma: life-threatening respiratory injuries. PMID- 6908142 TI - 'Humans are fragile; handle with care'. PMID- 6908145 TI - 'Will visiting hours even end?'. PMID- 6908144 TI - Under stress? Try laughing it off. PMID- 6908143 TI - Toward impeccable IV technique. A safe approach to IV antibiotics. PMID- 6908146 TI - [Giardiasis and amebiasis: symptoms, specimens, the counseling you'll need to do]. PMID- 6908147 TI - RN/MD team-up ... with no hassles. PMID- 6908148 TI - The drug interactions we all overlook. PMID- 6908149 TI - Is it a fungal infection, or VD? Sometimes only a culture can tell for sure. Save these guidelines for taking a specimen. PMID- 6908150 TI - Don't give up on the hopelessly obese. PMID- 6908151 TI - The factors contributing to obesity: an assessment tool. PMID- 6908153 TI - Sound off! Fun and frolic with 'unit dose'. PMID- 6908152 TI - Legally speaking: she wouldn't play by the rules. PMID- 6908154 TI - Where are the nurses? PMID- 6908155 TI - Plain talk about nursing. PMID- 6908156 TI - In business for health reasons. The joys and fears of independent practice. PMID- 6908158 TI - [A nurse in the city]. PMID- 6908157 TI - [Migrant children: their problems]. PMID- 6908159 TI - [At the Christian Center for the Health Professions: establishing one's profession]. PMID- 6908160 TI - [Dependency: a fact of life]. PMID- 6908162 TI - [Self determination of arterial pressure; yes or no?]. PMID- 6908161 TI - [Hello...hello...don't go away, you have a call!]. PMID- 6908163 TI - [CARPE: Center of Reception and Study of Early Infancy]. PMID- 6908165 TI - [Do budget restrictions in health care threaten quality of care?]. PMID- 6908164 TI - [Experts for nursing education in Brussels]. PMID- 6908166 TI - [Unemployment and mental health]. PMID- 6908167 TI - The complement system in uremia. AB - Plasma C1q, C1 esterase inactivator, C4, C3 and C3 proactivator were measured in 20 chronic uremic patients on maintenance hemodialysis, in 10 conservatively treated chronic uremic patients and in 20 healthy volunteers. There was no statistical significant difference between the patient groups in any of the measured complement components. The C1q, C1 esterase inactivator and C4 concentration were found to be the same in the patient and the control groups. The C3 and C3 proactivator levels were equally and significantly lower in both patient groups compared with the healthy volunteers. PMID- 6908168 TI - The art and science of supervision: too much of a good thing. PMID- 6908170 TI - What's happening in continuity of care? PMID- 6908169 TI - Breaking a turnover cycle--a successful approach. PMID- 6908171 TI - Motivation, management and the supervisory nurse. PMID- 6908172 TI - Multisensory modularized learning packages. PMID- 6908173 TI - Acknowledgement supports effective communication. PMID- 6908174 TI - Nursing management starts and succeeds with self-esteem. PMID- 6908175 TI - Law for the nurse supervisor; telephone orders. PMID- 6908176 TI - Can you keep a secret? PMID- 6908177 TI - The nurse in the corporate world. PMID- 6908178 TI - A systems approach to increased productivity. PMID- 6908179 TI - The transfer summary--an essential link. PMID- 6908180 TI - Four West Diners' Club. PMID- 6908182 TI - Controlling patient transportation. PMID- 6908181 TI - The motivation pyramid in nurse retention. PMID- 6908183 TI - Alcoholic patients in a hospital: model for change. PMID- 6908184 TI - A view from inside the patient gown. PMID- 6908185 TI - Short-cuts to problem solving. PMID- 6908186 TI - Law for the nurse supervisor. Refusal to treat patient. PMID- 6908187 TI - A shortage of nurses--or the sabotage of nursing? PMID- 6908188 TI - [Australia discusses also: nurses' changed responsibility conditions]. PMID- 6908190 TI - [Temporary employment]. PMID- 6908191 TI - [Intensive care nursing--care and/or technic?]. PMID- 6908189 TI - [Health education and guidance--only by professionals?]. PMID- 6908193 TI - [Geriatric nursing in institutions]. PMID- 6908192 TI - [Nurses and first line services in the Army]. PMID- 6908194 TI - [Study of alternative obstetric practice and new childbirth positions]. PMID- 6908195 TI - [Psychiatric nursing dilemma]. PMID- 6908196 TI - [Can we afford to sleep?]. PMID- 6908197 TI - [Part-time work--a special arrangement for women]. PMID- 6908198 TI - [Report from the Hygiene Group: cleaning of incubators]. PMID- 6908199 TI - [PPT (Pedagogic Psychiatric Service)--what is it?]. PMID- 6908201 TI - [Glimpse of psychiatric nursing in the USA]. PMID- 6908200 TI - [From the Scandinavian Research Seminar: maternity institutions in Scandinavia. Routines in relation to parents and siblings]. PMID- 6908202 TI - [Are you using approved disinfectants?]. PMID- 6908203 TI - [Health policy in the 80s]. PMID- 6908205 TI - [From the Lillehammer Conference: mental health protection--facts and expectations]. PMID- 6908204 TI - [Possibilities in primary nursing care]. PMID- 6908206 TI - [Lawyer's opinion: psychiatry should be standardized]. PMID- 6908207 TI - [Action mechanisms of analgesic agents and the body's own pain-relieving system]. PMID- 6908211 TI - [A great year for the elderly?]. PMID- 6908208 TI - [Nurses in primary health services--some challenging questions]. PMID- 6908210 TI - [Our priorities and temporary employment]. PMID- 6908209 TI - [Terminal care: a different student task]. PMID- 6908212 TI - [District midwives and families' need for services]. PMID- 6908215 TI - ["Sisteritis"]. PMID- 6908213 TI - [Nursing education at the college level]. PMID- 6908214 TI - [Helping profession and family life]. PMID- 6908216 TI - [Project relatives]. PMID- 6908217 TI - [Rubella vaccination]. PMID- 6908218 TI - [Aphasia patients--our forgotten group of handicapped?]. PMID- 6908219 TI - [Council for nursing education]. PMID- 6908220 TI - [Home nursing in Ostfold: recruitment and team work with primary care physicians]. PMID- 6908221 TI - [Care of children with cancer]. PMID- 6908222 TI - [Finnish health personnel under one "umbrella" and with a joint professional journal]. PMID- 6908223 TI - [Intelligence and skill in nursing care]. PMID- 6908224 TI - [Economic new thoughts and team work in the health sectors]. PMID- 6908225 TI - [We all work with the same goals; I have discovered no spooks. Interview by Bjorn H. Larssen]. PMID- 6908226 TI - [Nursing process: abstract concept or work tool?]. PMID- 6908227 TI - [Students' experiences from: a pioneer year in the Norwegian College of Nursing]. PMID- 6908228 TI - [Drug information: agents for the treatment of arrhythmias. Therapeutic main group: anti-arrhythmia agents. 14. Digitalis glycosides]. PMID- 6908229 TI - [Personnel evaluation can solve many conflict situations]. PMID- 6908230 TI - [Use your organization Danish Nursing Council]. PMID- 6908231 TI - [A busy start for the poor 80s]. PMID- 6908233 TI - [Pain and pain treatment. 2. Pain treatment with drugs]. PMID- 6908232 TI - [It would be ideal to employ visiting nurses]. PMID- 6908234 TI - [Statement concerning revision of wage budget 1981 for Odense Hospital: structure change can provide half of needed economy]. PMID- 6908235 TI - [Research and the Science Ethics Committee: make sure the weakest parts also receive safeguards]. PMID- 6908236 TI - [Regulated conditions for occupational health nurses]. PMID- 6908237 TI - [New Year's interview with Danish Nursing Council's president: nurses have, despite great pressure, managed to stick together]. PMID- 6908238 TI - [Is the sacred cow no longer quite so sacred?]. PMID- 6908239 TI - [How does nursing education in the Scandinavian countries agree with nurses' function in the respective countries. 3. Great need for the inhabitants' own cooperation]. PMID- 6908240 TI - [How does nursing education in the Scandinavian countries agree with nurses' function in the respective countries. 4. Nurses are specialists in their own field]. PMID- 6908241 TI - [Younger dentists in sugar action: sugar consumption is gradual by changing its structure]. PMID- 6908242 TI - [Application to Danish Nursing Council's executive board: desired interpretation of statute paragraph on representative election]. PMID- 6908243 TI - [Executive meeting 10-11 February: broad agreement on backing of negotiation lines]. PMID- 6908244 TI - [Danish Institute for Nursing Research is inaugurated today]. PMID- 6908245 TI - [My idea about school health care: a necessity that team work relations are utilized optimally]. PMID- 6908246 TI - [An average selected day for a school health nurse: rarely occasion to analyse a problem till it drops]. PMID- 6908247 TI - [Research in nursing]. PMID- 6908248 TI - [Problem solving: a characteristic for professional development]. PMID- 6908249 TI - [Resident exchange between Danish and Icelandic nursing homes: healthy to experience how others fare in the same situation]. PMID- 6908250 TI - [How does nursing education in the Scandinavian countries agree with nursing function in the respective countries. 5. Education has to a great extent compelling needs]. PMID- 6908251 TI - [How does nursing education in the Scandinavian countries agree with nursing function in the respective countries. 6. Clinical functions are characterized by routines]. PMID- 6908252 TI - [Former director in health administration, Eli Magnussen: where are the results of all these courses and of improved education?]. PMID- 6908254 TI - [Pain and pain treatment. 3. Problems of abuse in pain treatment]. PMID- 6908253 TI - [Clinical nurse specialist in function in Denmark: we have been able to offer children and their parents a lot of help]. PMID- 6908255 TI - [Home care nurses have published a pamphlet about their field of work]. PMID- 6908256 TI - [Adverse effects of dapsone (Avlosulfon)]. PMID- 6908257 TI - [Drug information: agents for the treatment of arrhythmias. Therapeutic main group: anti-arrhythmia agents. 16. (3). Anti-arrhythmia agents with action on ventricular arrhythmias]. PMID- 6908260 TI - [Care and teaching of a patient with cervical neck fracture. Teaching for increased abilities in self help]. PMID- 6908259 TI - [Community no. 2 gets 24-hour home care]. PMID- 6908258 TI - [The pregnant drug addict: great need for a concerted effort for a growing clientele of "narcobabies"]. PMID- 6908261 TI - [Interview with the director of the Danish Institute for Health and Nursing research: need for a Danish education in nursing research]. PMID- 6908262 TI - [Guidelines on income tax returns]. PMID- 6908263 TI - [Misuse of psychiatric treatment]. PMID- 6908264 TI - [Infant preventive care in Denmark. 1. A lot of variation in health visitors' work load]. PMID- 6908265 TI - [Infant preventive care in Denmark. 2. Remarkably many health visitors visit sick children]. PMID- 6908266 TI - [Legislation and nursing home rates]. PMID- 6908267 TI - [Misuse of psychiatric treatment. 2. Special psychiatric hospitals in the Soviet Union]. PMID- 6908268 TI - [Executive meeting 9-10 December: administrative nurses must have a solid basic knowledge through continued education]. PMID- 6908269 TI - [Drug information: agents for the treatment of arrhythmias. Therapeutic main group: anti-arrhythmia agents. 17. Mexiletine (Mexitil)]. PMID- 6908271 TI - [It requires consideration for prospects in purchasing Danish merchandise. Interview by Steffen Dalsgaard]. PMID- 6908270 TI - [Nursing process: an abstract concept or a working tool?]. PMID- 6908272 TI - [Administrator education in the public sector]. PMID- 6908273 TI - [Nursing education subject for researcher: modified teacher role will provide a better educated nurse. Interview by Inge Rosenkvist]. PMID- 6908274 TI - [Infant preventive care in Denmark. 3. Possible to reorganize health care without special standardization]. PMID- 6908275 TI - [Long-term evaluation following a course for psychiatric nurses: nearly everyone had acquired a more diversified view of treatment forms]. PMID- 6908276 TI - [Reform on a solid foundation is needed]. PMID- 6908277 TI - [Student nurse education in psychiatry and psychiatric health and nursing care: more attention to needs of students provides a more diversified education]. PMID- 6908278 TI - [Drug information: agents for the treatment of heart diseases. Last part]. PMID- 6908279 TI - [Statement on prescription drugs: nurses often have problems with strength conversion]. PMID- 6908280 TI - [Infant dosages and drugs]. PMID- 6908282 TI - [Danis Nursing Council has taken over school properties in Charlottenlund as of February 1: activities soon to start at the construction site]. PMID- 6908281 TI - [It is not dangerous says employer: up to fivefold of the limit values of anesthetic gases]. PMID- 6908283 TI - [Misuse of psychiatric treatment. 3. Prisoners of conscience's prospects of getting released]. PMID- 6908284 TI - [State hospital's pediatric orthopedic department GU 4054: we try to have as few rules as possible. Interview by Ulla Dietl]. PMID- 6908286 TI - [Disengagement certificate - a new concept in unemployment legislation: right to supplemental day money with exemption from termination notice]. PMID- 6908285 TI - [Development of a national and international network of research centers: will form a basis for a research tradition within nursing]. PMID- 6908287 TI - [Danish Nursing Council on education of nurses and radiographers in roentgen diagnosis and radiotherapy department: special education should be established with a reasonable geographic spread]. PMID- 6908289 TI - [Water is many things]. PMID- 6908288 TI - [Study of the health status of 19,000 school children in Copenhagen: geographic differences in the incidence of mental and social problems]. PMID- 6908291 TI - [What shall we do with research in nursing?]. PMID- 6908290 TI - [Sleep rhythms. How nursing personnel can contribute towards improved patient sleep during hospitalization]. PMID- 6908293 TI - [Ambulatory care of children with hip dislocation: cooperation with child's parents is the important thing]. PMID- 6908292 TI - [One earth, several worlds]. PMID- 6908294 TI - [Use of ethylene oxide in the hospital environment: hospitals could also use an effective occupational health service]. PMID- 6908295 TI - [Nurse administrators' perception of own role in team work with administrators and physicians: nursing has lived up to its responsibility in leadership functions]. PMID- 6908296 TI - [Part-time work is for many an invisible form of duress]. PMID- 6908297 TI - [How does nursing education in the Scandinavian countries agree with nurses' functions in the respective countries. 1. Nurses' possibilities to function according to the goals are limited]. PMID- 6908298 TI - [Team work in Scandinavia in joint education has been minimal]. PMID- 6908299 TI - [How does nursing education in the Scandinavian countries agree with nurses' functions in the respective countries. 2. Roles responsible for health and nursing care are of growing importance]. PMID- 6908300 TI - [Patient education with local steroid treatment of skin diseases: side effects greatly diminished with detailed instructions]. PMID- 6908301 TI - [Orthopedic Hospital's merger with Rigshospital: a little house inside a big house]. PMID- 6908302 TI - [An aid in blood sugar determination]. PMID- 6908303 TI - [The control of licensure and nursing practice]. PMID- 6908305 TI - [Acceptance of expanding role in public health nursing]. PMID- 6908304 TI - [Development of ethics and legislation in the public health system]. PMID- 6908306 TI - [Improve the environment to promote nursing career]. PMID- 6908308 TI - [A nurse who is an outstanding teacher]. PMID- 6908307 TI - [Creation of a model to survey and evaluate nursing performance]. PMID- 6908309 TI - [Nursing performance in Thailand]. PMID- 6908310 TI - [Advice for a would-be author]. PMID- 6908311 TI - [Nurses and children]. PMID- 6908312 TI - [Play and recreation for children]. PMID- 6908314 TI - [A study of factors influencing preschool children's nutritional status]. PMID- 6908313 TI - [Children's response to hospitalization and illness]. PMID- 6908315 TI - [Needs of parents of hospitalized children]. PMID- 6908316 TI - [Headache in children]. PMID- 6908318 TI - [Nurses and bedside nursing care]. PMID- 6908317 TI - [Attitude of student nurses and staff nurses toward pediatric nursing]. PMID- 6908319 TI - The mechanism by which the light chain of cleaved HMW-kininogen augments the activation of prekallikrein, factor XI and Hageman factor. PMID- 6908320 TI - [Encounter in the hospital - a study on how changes in health care affect communication and relations between nurses and patients. Society and health care a model]. PMID- 6908321 TI - [Research in the comprehensive health care field--a position paper]. PMID- 6908322 TI - [Research's connection with basic nurses education, Alnang School in Orebro]. PMID- 6908323 TI - [Perspectives in comprehensive health care research]. PMID- 6908324 TI - [Nursing education's connection with research; from practice to research]. PMID- 6908325 TI - [More women as school managers]. PMID- 6908326 TI - [Research's connection with nurse faculty education]. PMID- 6908327 TI - [Research's connection with the health sector]. PMID- 6908328 TI - [Researcher education and research in obesity]. PMID- 6908329 TI - [Health and nursing care legislation]. PMID- 6908330 TI - [Education in health care theory]. PMID- 6908332 TI - [Various teaching methods for nurses--exercises for the promotion of cooperation. II]. PMID- 6908333 TI - [Biological consequences of irradiation]. PMID- 6908331 TI - [The head nurse in the hospital. A concise report of a preliminary study]. PMID- 6908334 TI - [Nursing a hazardous occupation]. PMID- 6908335 TI - [Professional errors and their legal sequelae]. PMID- 6908336 TI - [Crisis center in mental health services]. PMID- 6908337 TI - [Allergy]. PMID- 6908338 TI - [The world diarrhea program]. PMID- 6908339 TI - [Discussion on euthanasia]. PMID- 6908340 TI - [Discussion on euthanasia. III. While writing on euthanasia]. PMID- 6908342 TI - [Epidural analgesia as pain control during parturition]. PMID- 6908341 TI - [Open visiting regulations in the pediatric department. Design, introduction and evaluation of an 'open' visiting regulation in the pediatric department in the Deaconess House of Leeuwarden]. PMID- 6908343 TI - [Managing of complaints in nursing homes]. PMID- 6908344 TI - [Infant health centers--sensible or not? A brief philosophy]. PMID- 6908345 TI - [The viability of psychiatric nursing]. PMID- 6908346 TI - [Intramural mental retardation services and nursing education in mental retardation care]. PMID- 6908347 TI - [Integrated approach: substance dependence. 1. Alcohol]. PMID- 6908348 TI - [Dependence on alcohol and drugs]. PMID- 6908350 TI - [The sequelae of prolonged use of drugs and alcohol]. PMID- 6908349 TI - [Why an article about the somatic sequelae of excessive alcohol use?]. PMID- 6908351 TI - [Integrated approach: substance dependence. 1. Alcohol. Giving or asking for help... What I wanted to tell you...]. PMID- 6908352 TI - [The neurological complications of chronic alcoholism]. PMID- 6908353 TI - [Alcoholism in women: experience from practice]. PMID- 6908355 TI - [A request of health personnel]. PMID- 6908354 TI - [Fetal alcohol syndrome]. PMID- 6908357 TI - [AA - Alcoholics Anonymous]. PMID- 6908356 TI - [Treatment clinic for persons with alcohol dependence problems]. PMID- 6908358 TI - [The viability of psychiatric nursing. III. Human vision important]. PMID- 6908359 TI - [Plea for a different kind of education]. PMID- 6908360 TI - [The Bill on Nursing Legislation]. PMID- 6908361 TI - [Team nursing in psychiatry - organization of the attention]. PMID- 6908362 TI - [Guiding employment socialization of the graduate from the Intermediary Professional Nursing Education program]. PMID- 6908363 TI - [Migraine]. PMID- 6908364 TI - [Function and place of nursing. This is how a patient can feel or where are we headed in the practice!]. PMID- 6908365 TI - [The patient's rights]. PMID- 6908366 TI - [Integrated approach: substance dependence. 2. Drugs. Addiction to drugs]. PMID- 6908367 TI - [Drugs and the Dutch Penal Code]. PMID- 6908368 TI - [Medical aspects of heroin dependence]. PMID- 6908369 TI - [Nomenclature of drugs]. PMID- 6908370 TI - [Indicating problems for nursing research]. PMID- 6908371 TI - [What is antipsychiatry?]. PMID- 6908372 TI - [This is how patients can feel...Something's wrong...]. PMID- 6908373 TI - Nursing role in office hand surgery. PMID- 6908374 TI - S. W. A. N. song. PMID- 6908375 TI - Hilke Lazzeroni: OR supervisor. Interview by Ann Caputo. PMID- 6908376 TI - Delivery of care to older people: issues and outlooks. PMID- 6908377 TI - Physical assessment of the elderly. PMID- 6908378 TI - Hearing loss and aural rehabilitation of the elderly. PMID- 6908379 TI - Maximizing psychological adaptation in an aging population. PMID- 6908381 TI - Health promotion and the assessment of health habits in the elderly. PMID- 6908380 TI - Promoting healthful aging through strengthening family ties. PMID- 6908382 TI - Sexuality in the later years. PMID- 6908383 TI - Chronic care and the elderly: impact on the client, the family, and the nurse. PMID- 6908384 TI - Aspects of aging in planned communities. PMID- 6908386 TI - [There is a need for the one stoma operation to be successful]. PMID- 6908387 TI - [20 participants in first course in stoma care]. PMID- 6908385 TI - [Kinin system of blood in respiratory and cardiopulmonary insufficiency in chronic bronchitis]. PMID- 6908388 TI - [Professional agreement: the State should keep Karolinska]. PMID- 6908389 TI - [Marianne Lundqvist on 1981]. PMID- 6908390 TI - [Team care in the nursing home - it is a question of creating one comfortable and normal last home in life]. PMID- 6908391 TI - [Health employees on strike in Poland: our wages are a sheer disgrace]. PMID- 6908392 TI - [Spri (Health Planning and Rationalization Institute) will reduce anesthetic gas leakages]. PMID- 6908393 TI - [Parttime employees: choose their own working time but lose benefits]. PMID- 6908394 TI - [With fairly simple methods irradiation of personnel and patients can be considerably reduced]. PMID- 6908395 TI - [Departmental chairman on her activities: a funny and formidable job. Interview by Inger Lernevall]. PMID- 6908396 TI - [She visits schools and tells about professions. Interview by Inger Lernevall]. PMID- 6908397 TI - [Studies show: hazards great in the laboratory environment]. PMID- 6908398 TI - [Personnel: we were surprised, did not believe it could be that bad]. PMID- 6908399 TI - [Gote Hansson, responsible politician: we shall do what we can to improve the working environment]. PMID- 6908400 TI - [Facts on Colombia: the professionally active individuals risk being fired]. PMID- 6908401 TI - [Facts on Colombia: problem with health services in the rural area - distances are great and there is lack of money]. PMID- 6908402 TI - [Increase knowledge on drug purposes for new agency]. PMID- 6908403 TI - [Annica, liaison person: I am no fiery spirit, but I like the profession. Interview by Viveka Holmerts]. PMID- 6908404 TI - [Inadequate supervision of a patient in the smoking room of the nursing home]. PMID- 6908405 TI - [Ingrid Mohlin, Matron: nursing department's need must be the starting point. Interview by Kristina Lindgren]. PMID- 6908406 TI - [We work to strengthen the matron's position]. PMID- 6908408 TI - [Anesthetist--a service unit whose only contacts are with needs]. PMID- 6908407 TI - [Inger, Lena and Ingrid are nurses in Huddinge Hospital. this is what they think of "Babels hus" on TV]. PMID- 6908409 TI - [Nattis provides security for children and parents]. PMID- 6908411 TI - [All collaborators--federation's jurisprudence not conclusive; the most important thing is that the right person gets elected as protection ombudsman]. PMID- 6908410 TI - [The new secrecy legislation - what does it comprise?]. PMID- 6908412 TI - [Scandinavian health care college: expanded viewpoint in health services in interdisciplinary education]. PMID- 6908413 TI - [3 shifts - good or bad? Many will be forced to close because of lack of ability]. PMID- 6908414 TI - [Complaint about treatment]. PMID- 6908415 TI - [Notification by relative about negligent treatment]. PMID- 6908417 TI - [3 shifts - good or bad? Necessary because nothing comes later in the profession]. PMID- 6908416 TI - [Mix up of blood in a blood transfusion]. PMID- 6908418 TI - [We work just like before - use common sense]. PMID- 6908419 TI - [Jonkoping: nurses in pools get assistant nurses' jobs. Interview by Viveka Holmertz]. PMID- 6908420 TI - [Legislation will be of great significance fo SHSTFs members]. PMID- 6908421 TI - [SHSTF alarmed about developments in surgery: those with basic education have shift duty and on-call duty]. PMID- 6908422 TI - [Erroneous administration of a drug]. PMID- 6908423 TI - [Continued discussion about secrecy legislation: law is being interpreted more restrictive than needed]. PMID- 6908424 TI - [Carin about her job as a physiology assistant: our future looks bright. Interview by Viveka Holmertz]. PMID- 6908425 TI - Brief report on "operation refugees: Matabeleland". PMID- 6908426 TI - Entrance to the E.E.C.--the effects on nursing education in England. PMID- 6908428 TI - The importance of practical teaching. PMID- 6908427 TI - Nursing research. PMID- 6908429 TI - Interaction of nursing services administration. PMID- 6908430 TI - Mental health--the constant in nursing. PMID- 6908431 TI - A.A.R.N. position statement on graduate education for nurses. PMID- 6908432 TI - A.A.R.N. starts work on blueprint for the development of nursing research in Alberta. PMID- 6908433 TI - Cimetidine as an adjunct to oral enzymes in the treatment of malabsorption due to cystic fibrosis. AB - The effects of two doses orally administered Cimetidine on gastric and acid production and on intestinal absorption in 13 patients with cystic fibrosis who were treated with pancreatin supplementation were studied. Although both doses of Cimetidine reduced the acid secretion significantly, no reduction in the steatorrhea and creatorrhea or increase in weight were found, although less pancreatin seemed to be inactivated while on cimetidine. It is concluded that pancreatic extract supplementation alone is not sufficient to normalise the digestion in cystic fibrosis. PMID- 6908436 TI - Mechanical ventilation. PMID- 6908434 TI - Kinins in relation to kallikrein activity, kininogen, electrolytes, aldosterone and catecholamines in urine from normal individuals. AB - The object of the present study was to test the hypothesis that urinary kinin excretion is an indicator of intrarenal kinin formation and to investigate urinary excretion of kinins in relation to natriuresis, kaliuresis, diuresis and urinary aldosterone and catecholamines in normal individuals on a free salt and water intake. In freshly voided urine collected from 24 normal individuals kinin concentration was directly related to kallikrein activity. Kininogen concentration was very low and neither related to kallikrein activity nor to kinin concentration. The excretion rates of kinins and kininogen were unrelated to the time interval between micturitions. In 24 hour urine collections from 50 normal individuals the excretion of kinins was positively correlated to natriuresis, kaliuresis and diuresis and also to dopamine but not to aldosterone, noradrenaline and adrenaline. Kinin excretion was inversely related to age and was lower in women than in men. On the basis of these results it is concluded that urinary kinin excretion reflects intrarenal kinin formation in normal ambulatory individuals and that urinary kinins are formed mainly in the interstitial and vascular space of the kidney. Furthermore, kinins and dopamine seem to play a physiological role in the renal handling of electrolytes and water. PMID- 6908435 TI - Temperature effect on cephalothin sensitivity of methicillin-resistant Staphylococcus aureus. AB - Nineteen methicillin-resistant Staphylococcus aureus isolates from clinical specimens were tested for cephalothin sensitivity by disk diffusion and tube dilution methods using incubation temperatures of 35 C and 30 C. Resistant colonies were observed to grow within the zones of antibiotic inhibition for 17 of the 19 isolates at 30 C but not at 35 C incubation. Twenty control strains known to be methicillin-sensitive did not show these resistant colonies at 30 C. Five of the methicillin-resistant isolates were sensitive, one of intermediate sensitivity to cephalothin, and the rest were resistent by tube-dilution testing at 35 C. At 30 C, however, two isolates were of intermediate sensitivity, and the rest were resistant to cephalothin by tube-dilution testing. These observations strongly suggest that the 30 C incubation temperature is more reliable in detecting in-vitro resistance of methicillin-resistant strains of Staphylococcus aureus to cephalothin in agar as well as in liquid media. PMID- 6908437 TI - Getting our act together. PMID- 6908439 TI - Work/study: a bridge to practice. PMID- 6908440 TI - Touching is for everyone. PMID- 6908441 TI - The psychological aspects of genetic counseling. PMID- 6908438 TI - Placebo response: myth and matter. PMID- 6908442 TI - Dealing with feelings. Disputing irrational thoughts. PMID- 6908443 TI - Correctional health care--beyond the barriers. PMID- 6908444 TI - A change process for prison health nursing. PMID- 6908445 TI - Nursing in juvenile corrections. PMID- 6908446 TI - Prison--a learning experience. PMID- 6908447 TI - Caring for the patient with chemotherapy-induced thrombocytopenia. PMID- 6908448 TI - Giving up smoking: a lesson in loss theory. PMID- 6908450 TI - Who is this nurse? PMID- 6908449 TI - Getting a new job. PMID- 6908451 TI - New student in psych. PMID- 6908452 TI - Programmed instruction. Patient assessment: examining joints of the upper and lower extremities. PMID- 6908453 TI - Antacid therapy. PMID- 6908454 TI - A judgment on standards. PMID- 6908455 TI - Nurse/judge attributes election to RN backing. PMID- 6908456 TI - Visual evoked potentials as an aid in evaluating brain dysfunction following concussional injury: an animal model. AB - Visual evoked potentials were recorded sequentially, using permanent epidurally implanted electrodes, before and after accelerating the heads of rabbits. The amplitude of VEP, recorded after lesioning, was diminished and recovery time was prolonged depending on the amount of acceleration and the extent of brain lesions found later in histological examinations. VEP reflected damage to the brain more precisely than EEG or somatosensory evoked potentials, thus giving values for judging the extent of lesions in patients with brain injuries. PMID- 6908457 TI - [Evidence for metabolites of the cornea (author's transl)]. AB - The supply of nutrient metabolites to the cornea is largely dependent on the levels of aqueous humour metabolites. When the ciliary body was destroyed totally by cyclodiathermy, a deficiency of glucose was observed in the aqueous humor and consequently in the corneal stroma. The diminished glucose levels could be increased by intravenous glucose infusions to values above normal. On the other hand, fructose infusions may be of value as nutrient metabolites of the cornea. Analyses of the fructose levels in the anterior segment of the eye showed that significant quantities of fructose were present in the corneal epithelium with a concentration gradient to the stroma and the aqueous humor. When the corneal epithelium was removed, the fructose of the corneal stroma and the aqueous humor was significantly diminished. In aphakic eyes without corneal epithelium, the fructose levels were decreased to nearly zero values both in the corneal stroma and in the aqueous humor. It was concluded that corneal epithelium was able to synthesize fructose and release it into the aqueous humor. PMID- 6908458 TI - [Importance of orientation on visual and neuronal resolution (author's transl)]. AB - Spatial resolution of gratings of different orientation has been evaluated in 39 patients, by means of projected slides and by laser interference fringes. Both methods reveal a significantly higher resolution (about 12%) for vertical or horizontal bars compared to oblique ones. The similarity of findings for both methods is indicative of the neuronal origin of this orientation-dependent effect and exclude an optical origin. PMID- 6908459 TI - [Utility of low light level television cameras for the fluorescein angiography of the retina (author's transl)]. AB - A survey of the major proportion of low-light level TV cameras available on the German market is described. A comparison and an assessment of the applicability of televised fluorescein angiography were carried out with the aid of technical data and measured results. It became evident that some systems were practicable for clinical use. With those it was possible to record angiograms at minimal illumination levels and patient inconvenience was reduced significantly. Measurements of blood flow parameters were possible with good temporal and geometrical resolution and full reproducibility. PMID- 6908461 TI - [Measurement of color-coordinates of the fundus by the color-comparison method with a widened measurement scale (author's transl)]. AB - The method of color measurements by visual comparison was first described in 1974, but the original method was not always adequate in documenting fundal changes in patients being treated with vasodilatators. In these cases the color coordinates reached the threshold of the measuring scale or went beyond it in the livid color area. A few years ago the color measuring instrument was supplied with a new filter system for this purpose and was necessary to move the left cornerpoint of the measuring scale far into the blue range. The instrument and the physical data are described, the standard color values x and y being found by transformational equations. The technical error was measured on a phantom eye. In a defined group of 100 normal eyes (=100 testing persons) the standard color values of the temporal and nasal papillary segments were measured. They are graphically demonstrated in the now widened x; y measuring scale. Clinical use and results will be described later. PMID- 6908460 TI - [HLA antigens in uveitis anterior (author's transl)]. AB - From January 1977 to May 1978, 101 patients with anterior uveitis were typed for HLA antigens. All came from the southwestern area of Germany, and 75 of these patients exhibited no signs of associated systemic disease (21 under 20 years of age, 54 over 20). In this group of 75 patients without associated systemic disease, a B27 frequency of 33.3% (8.9% in a random population) and a Cwl frequency of 16.0% (5.8% in a random population) was found as well as a B27-Cwl linkage of 13.3% (1.9% in a random population). A significant association with HLA antigens was found in (1) the adult form of anterior uveitis (disease onset over 20 years of age), namely, B27 antigen 38.9%, Cwl antigen 18.5%, B27-Cwl linkage 16.7%; and (2) male patients with anterior uveitis but without associated systemic disease, namely, B27 antigen 46.2%, Cwl antigen 17.9%, and B27-Cwl linkage 17.9%. No significant association with HLA antigens was found in (1) the juvenile form of anterior uveitis (disease onset under 20 years of age) and (2) female patients with anterior uveitis but without associated systemic disease. PMID- 6908462 TI - Experimental cryosurgical lesion of the optic nerve. AB - The right optic nerves of three cynomolgus monkeys were frozen under direct visualization after a modified Krohnlein operation. Left optic nerves were subjected to an identical procedure without freezing. Postoperatively, visual evoked responses (VERs) could not be obtained by stimulating right eyes, while electroretinograms from both eyes and VERs obtained by stimulating left eyes were normal. Extensive lesions which were found in the right optic nerves of all animals were histologically similar to those obtained by freezing in the brain. PMID- 6908463 TI - A case of central serous choroidopathy with peripheral retinal detachment. AB - A case of bilateral CSC is reported: a 36-year-old man, whose fluorogram showed a peculiar change of leak type, namely smokestack phenomenon to ink-blot, and then to descending type in succession. As the leak type changed to descending type, serous detachment of the macula extended to the inferior periphery, and shifting of subretinal fluid occurred. PMID- 6908464 TI - How good is normal visual acuity?. A study of letter acuity thresholds as a function of age. AB - Visual acuity levels were studied in 100 normal subjects of different ages, using a finely graduated letter chart under carefully optimized test conditions. Each line on the chart contained 10 letters of similar difficulty, arranged in random order. A statistical analysis of different response criteria showed a clear superiority of fractional criteria (e.g. 50% correct responses) over the traditional 100% correct requirement. The average difference between right and left eyes was 0.04 +/- 0.15 (decimal notation). Regression analysis of the dependence of visual acuity on age showed a monotonic rise towards the age of 25 years, and a gradual decline thereafter. The most marked decline occurred after the age of 60. Age-dependent confidence intervals were tabulated. The results indicate that minor modifications of the conventional test procedure can enhance the diagnostic potential considerably. PMID- 6908465 TI - Synaptic vesicle exocytosis in goldfish photoreceptor cells. AB - The photoreceptor cell endings of goldfish retinas were examined using ultrathin and freeze-fracture techniques. The synaptic vesicles could be seen lying closely packed in rows on each side of the synaptic ribbon, and the vesicles nearest to the end of the ribbon could be seen to be in direct contact with the presynaptic membrane. The openings of the synaptic vesicles to the synaptic cleft could also be observed at the presynaptic membrane nearest to the end of the ribbon, that is, 100 nm distant from the center of the apex. In the freeze-fractured replicas of the presynaptic membrane, the band-shaped membrane particle aggregation was seen at the apex and a row of the crater-like or circular protuberances were observed at each side of the apex. These structures were considered to be changes of the presynaptic membrane organizations according to the synaptic vesicle exocytosis. It may be possible that the synaptic vesicle exocytosis in the photoreceptor cells occurs at the sites of the presynaptic membrane nearest to the apical end of the synaptic ribbon, and that the exocytotic sites form a line on each side of the apex. PMID- 6908466 TI - Fine structure of trabecular meshwork and iris in pigmentary glaucoma. AB - Trabecular meshwork and iris were studied by light and electron microscopy in a 40-year-old female with pigmentary glaucoma. Elevation of the intraocular pressure was most likely due to closure the intertrabecular space by pigment granules and large cells resembling clump cells, fibrous substances, and hypertrophied endothelial cells of the trabecular sheet, which had phagocytized pigment granules. PMID- 6908467 TI - [Antibacterial in vitro activity of sulfurhexafluoride (SF6) (author's transl)]. AB - The sterility of the gas sulfurhexafluoride (SF6) was proved by means of microbiological examinations. It was also shown that sulfurhexafluoride has no antibacterial influence on important clinically relevant bacteria. PMID- 6908469 TI - Sex inequities cheat RNs, hearing told. PMID- 6908468 TI - Etomidate induced retinal changes. AB - The author examined the effect of etomidate-anaesthesia of one hour duration on the ultrastructure of the retina in animal experiments. Immediately after the exposure only the Muller's cells were moderately damaged. One day following the narcosis more serious pathological changes developed in the external nuclear layer which were partly irreversible. The changes found in the internal nuclear layer were less serious. The structure of the glial cells also altered. In the specimens taken 48 h following the anaesthesia the pathological changes of the neurons regressed to some degree, the Muller's cells reorganised and masses of glycogen accumulated in them. Further studies are needed to explain the eventual retinal toxic effect of this agent. PMID- 6908470 TI - Nursing shortage is acute, widespread. Hospitals face critical issues. PMID- 6908471 TI - Nursing shortage is acute, widespread. ANA President cites need for better salaries, work schedules. PMID- 6908472 TI - Being old and mentally healthy demands courage. PMID- 6908473 TI - As I see it... on the pain and power of organizing. PMID- 6908474 TI - RNs' hard work is key to labor gains. PMID- 6908475 TI - Table shows earnings, effects of inflation. PMID- 6908476 TI - Reagan budget proposes deep cuts in health programs. PMID- 6908477 TI - Employers must improve working conditions. PMID- 6908478 TI - Nurse legislator enjoys power of politics. PMID- 6908479 TI - Nurses deserve recognition and a good contract. PMID- 6908481 TI - Readers respond to Aiken editorial. PMID- 6908480 TI - As I see it... staff nurse cites frustrations, suggests remedies. PMID- 6908482 TI - ANA testifies on proposed budget cuts. PMID- 6908483 TI - California considers alternative licensure exam. PMID- 6908484 TI - Nurse Judy Runnels lobbies for Kansas Governor. PMID- 6908485 TI - Nursing school opens doors for American Indians. PMID- 6908486 TI - Shortcuts not the way to end nurse shortage. PMID- 6908487 TI - Creative policies help end frustrations for "burned out" nurses. PMID- 6908488 TI - Legislation: nursing takes stock of wins and losses in the last session. PMID- 6908489 TI - Getting through the management maze. PMID- 6908490 TI - Power: what nursing school never taught. PMID- 6908491 TI - An OR nurse manager's guide to budgeting. PMID- 6908492 TI - Stress and the OR nurse. PMID- 6908493 TI - A computer information system for the OR suite. PMID- 6908494 TI - A financial recording system for the OR. PMID- 6908495 TI - OR nursing law. PMID- 6908497 TI - Preparing a written research report. PMID- 6908496 TI - Speak out: chapters benefit from cooperating on joint workshop. PMID- 6908499 TI - Grandfather clause: right or privilege? PMID- 6908498 TI - Assessing the excretory system. PMID- 6908502 TI - A team approach to patient assignments. PMID- 6908500 TI - Experts stymied by mysteries of breast cancer. PMID- 6908501 TI - Nurses responsible for their own negligence. PMID- 6908503 TI - Ruby Gumdrop: OR teaching aid. PMID- 6908504 TI - Supply of experienced OR nurses should be number one priority. PMID- 6908505 TI - California challenges relevance and fairness of state board exam. PMID- 6908506 TI - Patient care in vascular surgery. PMID- 6908507 TI - Surgery for peripheral vascular disease. PMID- 6908508 TI - A technical look at vitrectomy. PMID- 6908509 TI - Assessing research for clinical use. PMID- 6908510 TI - Three ways to study for certification work well for nurses. PMID- 6908512 TI - Medical device regs: are they doing the job? PMID- 6908511 TI - How can we overcome barriers to preop interviews? PMID- 6908514 TI - Medical device regs: are they doing the job? Higher cost, even delayed availability, are a possibility. PMID- 6908513 TI - Medical device regs: are they doing the job? FDA and industry share common goal of device safety. PMID- 6908515 TI - Putting communication skills into practice. PMID- 6908516 TI - How to keep up with nursing while inactive. PMID- 6908517 TI - In Israel, organizing for the OR for mass casualties. PMID- 6908518 TI - Developing skills as a public speaker. PMID- 6908519 TI - Controlled breathing pattern in COPD. PMID- 6908521 TI - A procedure for goal setting: a method for formulating goals and treatment plans. PMID- 6908520 TI - Primary nursing in a rehabilitation hospital. PMID- 6908522 TI - Isolation and partial characterization of an elastase-type enzyme from human arterial wall by lima-bean trypsin inhibitor affinity chromatography. AB - A serine protease active on insoluble elastin at neutral pH has been isolated from human aortic media employing a Lima-bean trypsin inhibitor - Sepharose column. It is also hydrolyzed Suc (Ala)3 pna and casein but was found inactive against Benzoyl-Tyr-pna and Benzoyl-Arg-pna. Its apparent molecular weight as determined by SDS-PAGE was 22,300 Daltons. It differs from other elastases of human origin (human pancreatic elastase-1, human pancreatic elastase-2, human leucocyte elastase) on the basis of amino-acid composition and immunological specificity. PMID- 6908524 TI - S-bends. PMID- 6908523 TI - Aboriginal health: the gentle art of deception. PMID- 6908525 TI - An assessment guide for diuretics. PMID- 6908526 TI - The beginning of a professional life. PMID- 6908527 TI - Little risk that tampons cause toxic shock syndrome. PMID- 6908529 TI - Stress and distress: problems for us all. PMID- 6908528 TI - Adolescents burned as children. PMID- 6908530 TI - Stress and distress: the social worker's contribution. PMID- 6908531 TI - Stress and distress: the doctor/patient relationship. PMID- 6908532 TI - Stress and distress: treatment in psychiatry. PMID- 6908533 TI - A radioassay for proteolytic cleavage of isolated cartilage proteoglycan. 2. Inhibition of human leukocyte elastase and cathepsin G by anti-inflammatory drugs. AB - 20 non-steroidal anti-inflammatory drugs and other agents were evaluated for their effectiveness in directly inhibiting the proteolytic activity of human leukocyte elastase and cathepsin G. The proteolysis of hide powder azure by leukocyte granule extracts was used for initial testing, and selected drugs were then studied further using a radioassay of the proteolysis of isolated proteoglycan by purified leukocyte elastase and cathepsin G. The results indicated that at drug concentrations likely to be attained to vivo, phenylbutazone may significantly inhibit elastase, while gold thiomalate and mucopolysaccharide polysulfonic acid ester (MPSE; Arteparon) could limit the action of cathepsin G. Oleic acid may provide a useful starting point for development of agents specifically designed to inhibit cartilage erosion. PMID- 6908534 TI - Incorporation of labelled amino acids into proteins, from rabbit reticulocytes, retained on heparin-sepharose. AB - Fractions of rabbit reticulocyte lysates retained on heparin-Sepharose 4B catalyze incorporation of labelled amino acids into proteins in the absence of ribosomes, and several characteristics of this reaction are identical with peptide bond formation mediated by aminoacyl-tRNA-protein transferases. At least five different proteins become labelled, as revealed by polyacrylamide gel electrophoresis. Active fractions synthesize aminoacyl-tRNA which is utilized by transferase. Aminoacyl-tRNA-protein transferase activity may be uncoupled from that of aminoacyl-tRNA synthetase by puromycin or lysyl-phenylalanine which both inhibit the transferase activity only. Adenosine and phosphate inhibit aminoacyl tRNA synthetase as well as the incorporation of labelled amino acids into proteins. This indicates that the incorporation must be preceded by charging of tRNA with amino acids. Presence of three different aminoacyl-tRNA-protein transferases, each of them specific for a group of four amino acids, was demonstrated. Serum albumin stimulates the incorporation of amino acids and a labelling of this protein was demonstrated in mixtures into which it had been added. Addition of both ribosomal subunits and globin messenger ribonucleoprotein significantly changes the pattern of labelled proteins, and synthesis of globin was demonstrated by polyacrylamide gel electrophoresis. Density-gradient analysis revealed formation of a 48 S ribosomal complex and the formation of polyribosomes. Systems composed of active fractions retained on heparin-Sepharose supplemented with ribosomes and globin messengers apparently catalyze the translation of this message, but interactions do exist between the ribosome mediated peptide synthesis and non-ribosomal incorporation of amino acids into proteins. PMID- 6908536 TI - Resources for RN programs, educational mobility in the state. PMID- 6908535 TI - Effects of cholinergic stimulation on levels and fatty acid composition of diacylglycerols in mouse pancreas. AB - 1. During 15 min after intraperitoneal injection of 1 mg pilocarpine in vivo in the mouse, the level of diacylglycerol in the pancreas rose from 0.47 to 0.80 mumol per g wet weight. There were increase in the levels of all of the individual fatty acids which were measured in the diacylglycerol pool. The major increases were in palmitic and linoleic acids. These accounted for 65% o the total increase. 2. After in vitro incubation of mouse pancreas for 80 min, the levels of diacylglycerol (expressed in mumol/g wet weight) in unstimulated tissue and in tissue incubated with 10 micrometer or 100 micrometers acetylcholine (plus 100 micrometers eserine) were, respectively, 0.51 1.30 and 3.73. Increases in palmitic, oleic and linoleic acids in the diacylglycerol pool accounted for 75% of the total increase. With 100 micrometers acetylcholine, the proportions of individual fatty acids in diacylglycerol showed a significant enrichment of stearic and arachidonic acid at 40 min and of linoleic and arachidonic acids at 80 min. With the exception of an enrichment of stearic and arachidonic acids, the fatty acid composition of the new diacylglycerol resembled that of the triacylglycerol pool more closely than that of other classes of lipid in the pancreas. 3. After addition of atropine to acetylcholine-stimulated tissue, the level of diacylglycerol fell so that, after 40 min, the levels and proportions of all individual fatty acids in the diacylglycerol were not significantly different from those in unstimulated tissue. 4. In both the in vivo and in vitro experiments, the changes in levels of stearic and arachidonic acids in diacylglycerol indicated that only a small proportion of the total increase in diacylglycerol level could have been derived from the breakdown of stearoyl, arachidonoyl phosphatidylinositol which occurs in response to cholinergic stimulation in the pancreas. The major effect of acetylcholine in diacylglycerol metabolism in mouse pancreas in separate, therefore, from the effect on phosphatidylinositol metabolism. PMID- 6908537 TI - Changing the image of nursing in Pakistan. PMID- 6908538 TI - Quantity first, then quality: a hospital looks at cost-effective staff utilization. PMID- 6908539 TI - Two steps forward and one back: familial patterns of child abuse. PMID- 6908541 TI - A day to remember. PMID- 6908540 TI - Relieving the pain of accreditation. PMID- 6908542 TI - On becoming a public person. PMID- 6908543 TI - Nursing the well elderly. The health resource. PMID- 6908544 TI - You and the law: disciplinary action and the nurse. PMID- 6908545 TI - A simple purification procedure for rat pancreatic elastase and radioimmunoassay of the enzyme. PMID- 6908547 TI - Those baths. PMID- 6908546 TI - Demonstration of a local exhaustion of complement components and of an enzymatic degradation of immunoglobulins in pleural empyema: a possible factor favouring the persistence of local bacterial infections. AB - Local bacterial infections such as abscesses or purulent exudates most often contain numerous, easily culturable bacteria despite an intense inflammatory reaction characterized by the ingress of polymorphonuclear leucocytes. In order to understand the mechanisms leading to such a persistent infection, we used pleural empyema as a model and measured the levels and catabolism of complement as well as of immunoglobulins in 28 infectious pleural effusions associated with either a positive or with a negative bacterial culture. Classic and alternative pathway haemolytic activities, factor B and C4 haemolytic activities as well as native C3 were markedly decreased or undetectable in most culture-positive effusions when compared to culture-negative effusions (P less than 0.005); breakdown products of factor B and C3 were markedly increased in culture-positive fluids. Eleven out of 14 culture-positive fluids exhibited IgG breakdown as opposed to none of the culture-negative fluids. In seven out of 14 culture positive fluids, incubation with 125I-IgG led to their in vitro breakdown. This proteolytic activity could be abolished by preincubation of the culture-positive fluids with normal sera. Thus, increased catabolism of complement and breakdown of immunoglobulins, both leading to local consumption of immune reactants, could be one of the causes for bacterial persistence in pleural empyema. PMID- 6908548 TI - School nurses - the potential. PMID- 6908549 TI - School nurses - the potential. PMID- 6908551 TI - Stewart's standards. PMID- 6908550 TI - A healthier diet? PMID- 6908552 TI - Use of "DMSO" for unapproved indications. PMID- 6908554 TI - Visual field and perceptual deficits in the brain damaged patient. PMID- 6908553 TI - Nosocomial pneumonia. PMID- 6908555 TI - Anticoagulation therapy. PMID- 6908556 TI - Fungal infections in the compromised host. PMID- 6908558 TI - Evidence for an androgen-dependent urinary arginine esterase in the rat: separation from other urinary arginine esterases including kallikrein. AB - DEAE-Sephadex chromatography of male rat urine resolved three peaks of arginine esterase activity using the synthetic substrate alpha-N-p-tosyl-L-arginine methyl ester . HCl (Tos-Arg-O-Me). Esterase activity in peak 1 (esterase A1 fraction) was present in sexually mature males, but it was not found in mature females, castrated mature males, or sexually immature males. Urinary esterase A1 activity could be restored in castrated mature males by the administration of testosterone, and it is, therefore, androgen dependent. Esterase A1 activity was undetectable and could not be induced in females by daily doses of testosterone (up to 20 mg/day). The second urinary esterase peak (esterase A2 fraction) and the third peak (urinary kallikrein) were found in both male and female rats. Molecular sieve chromatography of esterase fractions A1, A2, and kallikrein, as determined by Sephacryl S-200 chromatography, gave single peaks of activity. Molecular weights were estimated to be 28,500, 42,000, and 41,500, respectively. Kinin-generating activities of esterases A1, A2, and kallikrein were also determined using dog plasma substrate. Esterase A1 fraction had no kinin generating activity, while esterase A2 fraction demonstrated significant activity but was 12 times less active than kallikrein per Tos-Arg-O-Me esterase unit. Esterase A2 fraction could not induce direct contraction of the rat uterus, and A2 did not cause a transient decrease in rat blood pressure when injected iv, both of which are criteria for kallikrein activity. It is concluded that the androgen-dependent Tos-Arg-O-Me esterase has properties quite different from both esterase A2 and kallikrein. Esterase A2 appears to be similar to the esterase A described in female rat urine by Nustad and Pierce. PMID- 6908559 TI - Contractile effect of vanadate and other vanadium compounds on the rat vas deferens. AB - Sodium metavanadate (NaVO3), vanadium pentoxide (V2O5) and vanadyl sulphate (VOSO4), evoked rhythmic and tonic contractions of the normal and reserpinized rat isolated vas deferens. Contractions were not observed by the use of vanadium trichloride (VCl3) The order of potency of these compounds, for their maximum contractile effects was NaVO3 greater than V2O5 greater than VOSO4 greater than VCl3. Differences in pD2 values were less than 0.5 long units in relation to the first compound. Vanadium-induced contractions were blocked by Ca2+ deprivation, nifedipine, Mg2+, Mn2+, Ni2+ and Co2+, indicating the involvement of a loosely bound or extracellular calcium-dependent mechanism. It is still unclear whether this calcium translocation was related, or not, to changes in Na+, K+-ATPase activity. Since ouabain blocked the action of vanadyl or vanadate non competitively, it is concluded that vanadium compounds and ouabain induce their effects by interacting with different sites in vas deferens, both of which may or may not be located on the (Na+, K+)ATPase enzyme complex. PMID- 6908560 TI - [Stomach cancer]. PMID- 6908557 TI - [Lung disease after long-term inhalation of organic dusts in employees of a drug firm (author's transl)]. AB - Nine patients, as employees of a drug firm exposed to pancreatin and other organic substances in dust form for long periods of time, complained of non specific breathing disorders and exercise dyspnoea. Investigation revealed predominantly restrictive-obstructive disorders of ventilation with diffuse emphysema and evidence of abnormal oxygen diffusion. In two patients the chest X ray revealed signs of acute alveolitis, in a third a marked pulmonary fibrosis after exposure for several years. Six of seven patients reacted positively to a prick test with pancreatin. Precipitating antibodies were demonstrated in only one patient. Immunopathological and chemical-toxic effects of pancreatin dust may be causes of the described pulmonary disease. PMID- 6908561 TI - [Traumatic dislocations]. PMID- 6908562 TI - [Differential diagnostic importance of pain in the joints]. PMID- 6908563 TI - [Cesarean section in modern obstetrics (1.)]. PMID- 6908564 TI - [Organization and management of prophylactic inoculations of children]. PMID- 6908566 TI - [Endemic goiter]. PMID- 6908565 TI - [Management of pregnancy and labor in umbilical pathology]. PMID- 6908568 TI - [Dog rose]. PMID- 6908567 TI - [Infant mortality in foreign countries]. PMID- 6908571 TI - [Disinfection of milk glassware and equipment]. PMID- 6908569 TI - [Female hygiene (subject matter and content for talks)]. PMID- 6908570 TI - [Dissemination and study of the knowledge of the urban population of prevention and early detection of tuberculosis]. PMID- 6908572 TI - [Seafood products in human nutrition]. PMID- 6908573 TI - [Rules for taking medicines]. PMID- 6908574 TI - [Dispensary care of children suffering from cardiovascular diseases]. PMID- 6908575 TI - Task force on credentialing in nursing presentation on structure. PMID- 6908576 TI - The effect of low-molecular-weight inhibitors on the growth in vitro of a human pancreatic adenocarcinoma cell line. PMID- 6908577 TI - [Two new methods for the determination of serum elastase activity and their clinical significances (author's transl)]. PMID- 6908578 TI - [Useful diagnostic tests in obesity]. PMID- 6908579 TI - [Female sterility]. PMID- 6908580 TI - [Pain and anal gesics]. PMID- 6908581 TI - [Migraines and anti-migraine drugs]. PMID- 6908582 TI - [Alcohol, biology and health of the child]. PMID- 6908583 TI - [Hysterical neuroses]. PMID- 6908584 TI - [Toxoplasmosis]. PMID- 6908585 TI - [Social security in the framework of the European Economic Community]. PMID- 6908586 TI - Certification for infection control practitioners: the time is now. PMID- 6908588 TI - Applied statistics in infection control. Sources of variation in data. PMID- 6908587 TI - Hospital hygiene in the German Democratic Republic. PMID- 6908589 TI - The professionalization of nursing: United States and England. PMID- 6908590 TI - Accountability--definition and dimensions. PMID- 6908591 TI - The deposition, distribution and retention of inhaled 239PuO2 in the lungs of rats with pulmonary emphysema. PMID- 6908594 TI - The abdication of the role of health education by hospital nurses. AB - As nurses are in a unique position to influence patients and so carry out health education to their 'captive audience', it is pertinent to discuss why so many nurses appear to abdicate this role. Reasons are suggested that the nurses' own education has failed to equip her with the skills necessary for the fulfilment of this role. Even basic communication skills appear to be poorly developed, let alone the more complex and analytical skills required by the nurse in order to effectively deliver a planned programme of health education to either individual patients or groups. A Health Belief Model (HBM) has been discussed and is proposed as a useful framework around which the nurse can formulate her health teaching. Variables to be considered include motivation, value of illness threat reduction, probability that compliant behaviour will reduce the threat of illness, and modifying and enabling factors. The HBM should be incorporated into a individualized nursing care plan, so that health teaching is an integral part of the patient's planned care in hospital. The ward sister is the key figure in implementing such procedures, and it is to her that education should also be directed. PMID- 6908593 TI - The effect of music on the pain of selected post-operative patients. AB - The study investigated the effect of music (musical preferences of subjects) on the pain of selected post-operative patients during the first 48 hours. The subjects were 24 female gynaecologic and/or obstetric patients who made the control and experimental sample, paired accordingly by age, type of surgery, educational background and previous operative experience(s). The measurement of the experimental variable was done using an Overt Pain Reaction Rating Scale (OPRRS) devised by the writer. Analgesics received, arterial blood pressures, pulse rates, and respiratory rates were also used to test the hypothesis. Significant differences were found between the groups of post-operative patients in their musculo-skeletal, and verbal pain reactions during the first 58 hours at the 0.05 level. The blood pressures showed significance only at the 0.07 level. The pulse rate during the second 24-hour period was significant at the 0.01 level; however, no significance was shown during the first 24-hour period. The respiratory rate was insignificant during the first 48-hour post-operative period. The raw data on pain-relieving medications received by the sample indicated a difference, but this was not statistically significant. The conceptual framework of the study was based on the concept of distraction following the 'Gate Control Theory' of pain by Melzack & Wall (1965). The recommendation arrived at is to use music as a nursing measure for post-operative patients. PMID- 6908592 TI - Characterization of eukaryotic initiation factor 2 containing two polypeptide chains of Mr = 48,000 and 38,000. PMID- 6908595 TI - Improvement of quality of nursing care: a goal to challenge in the eighties. AB - Some general thoughts on the use of the quality concept as a means to structure critical reflection on patient-client care and health services is discussed. The continuous request for more health care facilities and quality of services occupies not only the minds of the health workers, but also of the consumer who is becoming more aware of his rights and privileges. Health care should not be identified with curative care only. It involves prevention and promotion of people's status of health as well. Nurses have an important contribution to make in the promotion of health. The paper deals also with the evaluation of quality of care. If nurses become involved in the evaluation of nursing care they should have a clear concept of what nursing is. The nursing profession has a responsibility to develop standards and criteria for the evaluation of nurses' contribution in patient care. An example of a well-tested monitoring quality instrument is given. In the last part of the paper some practical suggestions for managers who are responsible for the quality care improvement in their own health care institutions are given. PMID- 6908596 TI - The accuracy of nurses' knowledge about survival rates for early cancer in four sites. AB - To consider the role of nurse education in the development of a body of professional knowledge about cancer, trained nurses (n = 372), learners (n = 160) and auxiliaries (n = 238) were asked, by means of a postal questionnaire, to estimate the 5-year survival rates for early cancers in four sites: breast, cervix, skin and lung. Among trained nurses only a minority had accurate knowledge; four to five out of ten answering accurately for breast, cervix and lung, but only two in ten for skin. All three grades were less well informed about skin cancer. For all sites trained nurses were more likely to be accurate than learners or auxiliaries, but the variations were statistically significant only for skin and cervix. Taking auxiliaries as a baseline the degree of differentiation between their knowledge and that of the SRNs was disappointing. Nurses' reliance on bedside experience as their major source of information about cancer is suggested as one explanation for their levels of knowledge. The implications both for the nurse's role in health education and for nursing education are discussed. PMID- 6908597 TI - Making use of unsolicited research data. AB - Two hundred and fifty-one unsolicited comments, relating in general terms to the research subject, were recorded during the collection of data for the writers current research concerning the role of the psychiatric nurse. The paper demonstrates how such 'unofficial' comments may be used to further our understanding of the research process generally and of the research subject in particular. The comments are analysed and used to highlight a number of areas which are of concern to nurses, for example the difficulty which some respondents had with thinking about nursing activity in specific terms, and relating it to individual patients. The role of trade unions in the decision making process preceding, and following, entry to data collection sites is discussed. That lines of communication between the researcher, nurse administrators and trade unions be clarified is one of the recommendations made in this paper. Other recommendations include the proposal that, where possible, research respondents be given an opportunity to make general and specific comment relating to the research in which they are being asked to participate. PMID- 6908598 TI - The implementation of nursing research related to the nursing profession in Northern Ireland. AB - Adopting the holistic approach to the definition of nursing as purported by Treece & Treece (1977), this paper presents the findings of the reported efforts of five grades of nursing personnel, directly involved in hospital care in Northern Ireland, to utilize research information in their area of work during the 12 months up to Spring 1979. It draws the conclusion that these groups have not yet begun to identify to any great extent the importance of research to nursing practice, or with the need to devise a process through which research can be implemented and evaluated. PMID- 6908599 TI - Self-directed learning and student selected goals in nurse education. AB - This paper is a consideration of the philosophy of, and research into, general education. It examines some of the approaches to education and a small part of the research into discovery learning, self-directed study and student-selected goals of learning. Proposals are made for a single module of nurse training for admission to the register of general nurses which incorporate the philosophy and research-based ideals of self-directed learning. Finally, problems which may be anticipated in its implementation are discussed but no firm conclusions are drawn until these can be based on fact rather than conjecture. PMID- 6908600 TI - Health policy in the nursing curriculum: why do we need it? PMID- 6908601 TI - Sexual adjustment after a hysterectomy. PMID- 6908602 TI - Preparation for childbirth: a Cesarean birth series. PMID- 6908603 TI - Evaluation of nurse-initiated telephone calls to postpartum women. PMID- 6908605 TI - Nurse-midwifery management of health care for pregnant adolescents. PMID- 6908604 TI - Adolescent sexuality and pregnancy. PMID- 6908606 TI - IgG on mouse erythrocytes augments activation of the human alternative complement pathway by enhancing deposition of C3b. PMID- 6908607 TI - Effect of Colchicine, vinblastine, D2O and cytochalasin B on elastase secretion, protein synthesis and fine structure of mouse alveolar macrophages. PMID- 6908608 TI - [Study of disc method for determining bacterial sensitivity to a combined preparation of ampicillin and cloxacillin (author's transl)]. PMID- 6908609 TI - [Obstetrical practice and medical ethics]. PMID- 6908610 TI - [The ethics concerning the matters of life and death and the response of the medical profession. A discussion]. PMID- 6908611 TI - [Midwifery practice and professional ethics]. PMID- 6908612 TI - [Creation of life and medical ethics: the meaning of birth]. PMID- 6908613 TI - [Medical practice based on love]. PMID- 6908614 TI - [Medicine and consumer's movements: rights and responsibilities of the patient]. PMID- 6908615 TI - [A report from the United States: tampon toxic shock syndrome]. PMID- 6908616 TI - [Sinusodial NST (non-stress test)]. PMID- 6908618 TI - [Characteristics of experimental studies in life sciences]. PMID- 6908617 TI - [Progress in mankind and experimental studies]. PMID- 6908619 TI - [Characteristics of experimental studies in psychology]. PMID- 6908620 TI - [Characteristics of experimental studies in education]. PMID- 6908622 TI - [Relationships of processes of care to patient outcomes]. PMID- 6908621 TI - [Significance of experimental studies in nursing research. Discussion]. PMID- 6908623 TI - [Women's knowledge about menopause]. PMID- 6908624 TI - [Characteristics of experimental studies in physics]. PMID- 6908627 TI - [Pleasure in doing research]. PMID- 6908626 TI - [Attitude to research]. PMID- 6908625 TI - [Developmental changes of nursing students help-oriented cognition and nursing behaviors toward dying patients]. PMID- 6908629 TI - [Morals in research]. PMID- 6908628 TI - [Significance in planning research]. PMID- 6908630 TI - The Kansas Nurse visits a meeting of the State Board of Nursing. PMID- 6908631 TI - Modern nursing education in a rural setting: pittsburg State University. PMID- 6908632 TI - Update: toxic shock syndrome. PMID- 6908633 TI - Evaluating the effectiveness of an anti-smoking program. PMID- 6908634 TI - A nutrition component for high school health education curriculums. PMID- 6908635 TI - Redefining school health services: comprehensive child health care as the framework. PMID- 6908636 TI - Taking the disaster out of disease education. PMID- 6908637 TI - School mental health services following an environmental disaster. PMID- 6908638 TI - Problems faced in developing a state constituent organization. PMID- 6908639 TI - Is there a relationship between drug use and academic achievement? PMID- 6908640 TI - Occupational stress. Coping and health problems of teachers. PMID- 6908641 TI - Development of a high school health education curriculum. PMID- 6908642 TI - The 1985 resolution and the nursing shortage: another viewpoint. PMID- 6908643 TI - Effective grievance processing Part II. PMID- 6908644 TI - An innovative approach to the delivery of behavioral services in Worcester County. PMID- 6908645 TI - Getting a bachelor's degree? PMID- 6908646 TI - [Use of pereflat in the systematic preparation for echography exams of the abdomen and of the pelvis (apropos of 1000 cases)]. PMID- 6908648 TI - Neutrophil elastolytic activity in adult respiratory-distress syndrome. PMID- 6908647 TI - Complement proteins and macrophages. II. The secretion of factor B by lipopolysaccharide-stimulated macrophages. AB - The secretion of factor B by mouse peritoneal macrophages was found to be enhanced following in vivo or in vitro stimulation with lipopolysaccharide (LPS). The intravenous administration of LPS to mice of various strains caused an increased release of factor B but not the release of acid phosphatase by the peritoneal macrophages obtained from the stimulated mice. In vitro stimulation of cultured macrophages with LPS resulted in an enhanced secretion of both factor B and acid phosphatase. The dose-dependent augmentation of factor B secretion by LPS was found in the macrophages from LPS-responsive C3H/HeN mice, whereas the macrophages from LPS-unresponsive C3H/HeJ mice did not respond to either phenol extracted LPS or butanol-extracted LPS. The ability of LPS to cause the enhancement of factor B secretion by macrophages was abolished by alkali or acid treatment of LPS, indicating that its lipid A part was responsible for the observed effect. PMID- 6908649 TI - What's in the air of the operating theatre? PMID- 6908650 TI - The 37 1/2 hour working week for nurses, its implementation and implications in the operating department: NATN/Surgikos Scholar Award 1980. PMID- 6908651 TI - Activation of the alternative complement pathway by unidentified substances in human glomerulonephritis. AB - Activation of the alternative complement pathway (AP) has been investigated in 79 serial serum samples obtained from 28 patients which had different types of glomerulonephritis. Serum factors activating the AP of the complement system have been detected in 12 patients with various forms of glomerulonephritis. Immune complexes (IC), levels of complement components of the classical and the alternative pathways and cobra venom factor activity were measured. Serum specimens were subcategorized as 2 study populations: (i) patients with serum factors activating AP and (ii) patients with both serum activators and IC. Although CoVF-AH50, properdin factor B and C3 concentrations were comparably depressed in these two groups, the levels of Clq and C4 were very low only in patients with circulating IC. These data were highly suggestive of AP activation due to serum factor. In contrast the patients also showing circulating IC had activation of both pathways. The presence of these factors suggests that renal damage can be determined by other immunological stimuli. PMID- 6908652 TI - Reflections on a television image: the nurses 1962-1965. PMID- 6908653 TI - Nurse abuse--nurse abusers. PMID- 6908654 TI - A council of staff nurses: a proposal. PMID- 6908656 TI - Washington focus. Nursing and the proposed budget. PMID- 6908655 TI - A clinical preceptorship to prepare reality based ADN graduates. PMID- 6908657 TI - Curing with kindness. PMID- 6908658 TI - Three more gastrointestinal tests--and how to help your patient through each. PMID- 6908659 TI - Chest tubes. They're really not that complicated. PMID- 6908661 TI - Sperm to bank on. PMID- 6908660 TI - Taking your part in the fight against testicular cancer. PMID- 6908662 TI - Teenage mother...high-risk baby. PMID- 6908663 TI - Skillcheck: on assessing respiratory function. PMID- 6908664 TI - New drugs. PMID- 6908665 TI - Test your knowledge of caring for the patient with peptic ulcer. PMID- 6908666 TI - Discharge planning: good planning means fewer hospitalizations for the chronically ill. Nursing grand rounds. PMID- 6908667 TI - Helping your diabetic patients help themselves. PMID- 6908668 TI - Diabetes: how your patient looks at it. PMID- 6908669 TI - Managing your time. PMID- 6908671 TI - Voice of the ward sister. Interview by Celia Fairbrother. PMID- 6908670 TI - Staff participation in management decision-making. PMID- 6908672 TI - Talking to Sister Rosemary Walsh. PMID- 6908673 TI - Law Lords split on prostaglandin abortion. PMID- 6908674 TI - Another look at the selection interview. PMID- 6908675 TI - Mine rescue workers: their perceived health and absence from work. PMID- 6908676 TI - The body's reaction to noise. PMID- 6908677 TI - Safety: Inside information. PMID- 6908678 TI - The NHS and the psychiatrically ill worker--2. PMID- 6908679 TI - Occupational lung disease: pneumoconiosis. PMID- 6908680 TI - Pathways of progress. PMID- 6908681 TI - Aviation opportunities for occupational health nurses. PMID- 6908683 TI - A simple hypertension screening program. PMID- 6908682 TI - Continuing education: who needs it? PMID- 6908684 TI - American Association of Occupational Health Nurses, Inc. Statement and suggested guidelines OSHA Standard 29 CFR 1910.20, Access to Employee Exposure and Medical Records. PMID- 6908685 TI - Trazodone. PMID- 6908686 TI - The practice of assertiveness. PMID- 6908688 TI - The use of health education as a form of societal control. PMID- 6908689 TI - Paternalism in health care. PMID- 6908687 TI - Health education series--Article II. Body mechanics. Lifting, pushing and sprains. PMID- 6908690 TI - Clinical sites used in baccalaureate programs. PMID- 6908692 TI - The nursing shortage: an optimistic view. PMID- 6908691 TI - Nursing in the future. PMID- 6908694 TI - Doctoral curricula in nursing. PMID- 6908693 TI - Teaching assertiveness to seniors. PMID- 6908695 TI - Problem patients or problem nurses? PMID- 6908696 TI - The dilemma of duality. PMID- 6908697 TI - Every nurse's responsibility: Standards of care. PMID- 6908698 TI - Communication skills. Talking points 11. The doctors have told, haven't they? PMID- 6908699 TI - Who am I? Where am I? Why do I hurt so much? Standards of care. PMID- 6908700 TI - Nursing care study: hills of freedom. PMID- 6908701 TI - Fats and heart disease: a reply. PMID- 6908702 TI - Care of the profoundly handicapped in the Netherlands. PMID- 6908703 TI - SNIPPET. A computerised nursing information bank. PMID- 6908704 TI - A psychiatric sister's ABC--6. PMID- 6908705 TI - A study on internship of B.Sc. nursing programme at College of Nursing P.G.I. Chandigarh. PMID- 6908706 TI - A model of anesthesia training programme for nurses. PMID- 6908707 TI - Character first, career next. PMID- 6908708 TI - Peritoneal dialysis in industrial hospital. PMID- 6908709 TI - Clinical forum 4. Mental handicap. PMID- 6908710 TI - Mental handicap: making progress. PMID- 6908711 TI - Mental handicap: colleagues, not experts. PMID- 6908712 TI - Mental handicap: the consultant's challenge. PMID- 6908713 TI - Mental handicap: a joint approach to a new kind of help. PMID- 6908719 TI - Thyrotoxicosis. PMID- 6908715 TI - The second coming. PMID- 6908714 TI - Mental handicap: what is an artist doing here? PMID- 6908716 TI - Psychiatry. 4. Drugged to the eyeballs. PMID- 6908717 TI - District nurse training. 2. How to catch and keep your district nurse. PMID- 6908718 TI - Nursing in Asia. 3. Space, the final frontier. PMID- 6908720 TI - When caring's a matter of policy. Travel scholarship. PMID- 6908721 TI - Paranoid states: seeing things. PMID- 6908724 TI - Male midwives: will they be denied a chance? PMID- 6908723 TI - RCN conference on standards of nursing care. Wanted: a clinical revolution. PMID- 6908722 TI - Nursing care study. Thyroidectomy: a strangling feeling. PMID- 6908725 TI - Victims of the Iranian hostage crisis: nursing interventions. PMID- 6908727 TI - Dealing with controversy, Part II: guiding nursing students into troubled waters. PMID- 6908726 TI - Patient rights: an agenda for the '80s. PMID- 6908729 TI - Nurse-specialists: malpractice targets - 1981. PMID- 6908728 TI - [The practical importance of the newly introduced antibiotics (author's transl)]. PMID- 6908730 TI - Theft in hospitals: investigations and accusations. Case in point: Newman v. Greater Kans. City Bapt. Hosp. (604 S.W. 2d 619 - MO.). PMID- 6908731 TI - Legal case briefs for nurses. N.Y.: nurses bungled orders: M.D. cleared. CO.: nurse witness helps M.D. defendant. PMID- 6908732 TI - O.R. nurses: important trial witnesses. Case in point: Stevens v. Union Memorial Hospital (424 A. 2d 1118 - MD.). PMID- 6908734 TI - Sex Q & A: frank answers to your most delicate patient-counseling questions. PMID- 6908733 TI - The staffing mess: who can we turn to? PMID- 6908736 TI - Back from burnout. PMID- 6908735 TI - How close are you to burnout? PMID- 6908737 TI - Bringing them back out of renal shutdown. PMID- 6908738 TI - Toward impeccable IV technique. When you have to reconstitute meds? PMID- 6908739 TI - Put the patient's leg on ice? PMID- 6908740 TI - 'Take with meals'...or not? Quick answers to a pesky question. PMID- 6908741 TI - A new procedure...A sudden complication...What's your diagnosis? PMID- 6908742 TI - Urgent priorities in severe trauma. Stab and crush wounds to the heart. PMID- 6908744 TI - Now: an alternative to breast cancer surgery. PMID- 6908743 TI - Essential precautions with IV solutions. You can't be casual...even with normal saline. PMID- 6908745 TI - Drug therapy today. Progress report: preventing post-MI thromboembolism. PMID- 6908746 TI - Legally speaking. You can't escape the good Samaritan role--or its risks. PMID- 6908747 TI - The law and your practice. PMID- 6908748 TI - Assistance for education: #2 in series on available scholarships by the Subcommittee on Scholarships by the Council on Education. PMID- 6908749 TI - Urinary kallikrein and hypertension in cadmium-exposed rats. AB - Chronic exposure of rats to cadmium (Cd) in drinking water induced elevated systolic and diastolic blood pressure. Heart rate, however, was lowered, suggesting that the hypertension in these rates may be due to an increase of the total peripheral resistance, possibly involving a central nervous system (CNS) component in Cd-induced hypertension. Urinary kallikrein activity was reduced in the exposed animals and may explain the previously reported antinatriuretic effect of Cd, since renal kallikrein is an enzyme responsible for the synthesis of kallidin, a potent vasodilator and natriuretic polypeptide. PMID- 6908750 TI - Evaluation of renal function--1: blood urea nitrogen and creatinine determinations. PMID- 6908751 TI - The avermectin complex: a new horizon in anthelmintic therapy. PMID- 6908752 TI - Sexual behavior in mares. PMID- 6908753 TI - Errors in radiography that interfere with diagnosis. PMID- 6908754 TI - Cryosurgical treatment of glaucoma in a horse. PMID- 6908755 TI - Blastomycosis: a practical therapeutic approach (a review of 26 cases). PMID- 6908756 TI - Neurologic signs associated with congenital anomalies in a Yorkshire terrier. PMID- 6908758 TI - Data base for weight loss and chronic diarrhea--2. PMID- 6908757 TI - Three concurrent urinary diseases in a cat: urinary obstruction, hypoplasia of the kidney, and nephritis caused by feline infectious peritonitis. PMID- 6908760 TI - Efficacy of oxfendazole in reducing bovine helminthiasis in field trials. PMID- 6908759 TI - IgG immunodeficiency in a half-Arabian foal with salmonellosis. PMID- 6908761 TI - Changes in components of sera from calves after injections of adult bovine serum. PMID- 6908762 TI - Comments on canine castration. PMID- 6908763 TI - Comments on canine castration. PMID- 6908764 TI - Evaluation of renal function-3: Evaluation, treatment, and management of patients with chronic primary renal failure. PMID- 6908765 TI - Behavioral histories. PMID- 6908766 TI - A modified treatment of equine uterus. PMID- 6908767 TI - An outbreak of Bordetella bronchiseptica respiratory disease in foals. PMID- 6908768 TI - Chemotherapy of a dog with malignant lymphoma. PMID- 6908769 TI - Urolithiasis in an 11-week-old kitten. PMID- 6908770 TI - Tape muzzle for mandibular fractures. PMID- 6908771 TI - Correction of contracture of the quadriceps muscle. PMID- 6908772 TI - Insect-contaminated dog food. PMID- 6908773 TI - Clinical evaluation of Panolog Cream used to treat canine and feline dermatoses. PMID- 6908774 TI - Hypertrophic pulmonary osteoarthropathy. PMID- 6908775 TI - Abdominal tumor affecting flight. PMID- 6908776 TI - Upper airway of the California sea lion: an anesthetist's perspective. PMID- 6908777 TI - Improving blood smears and staining techniques. PMID- 6908778 TI - Food-animal regional anesthesia. Caprine blocks: cornual. PMID- 6908779 TI - Mixed sweat gland tumor in a bull (a case report). PMID- 6908780 TI - Programmable calculator program for assessment of losses due to subclinical mastitis. PMID- 6908781 TI - Congenital internal hydrocephalus in Polled Hereford cattle. PMID- 6908783 TI - Finding the right employee: 5 simple steps. PMID- 6908782 TI - Repair of entropion in the lamb. PMID- 6908784 TI - A court sets the value of a dog. PMID- 6908785 TI - Porous plastic implants. PMID- 6908786 TI - [Blood system kinin components in rheumatoid arthritis]. PMID- 6908787 TI - Ambulatory maternity health care: bicultural aspects. PMID- 6908789 TI - Initiating a comprehensive study of the Virginia Nurse Practice Act. PMID- 6908788 TI - Nursing shortage: conditions not numbers. PMID- 6908790 TI - Rx for reality shock: a care plan for the new nurse. PMID- 6908791 TI - Advocacy: a function of the community mental health nurse. PMID- 6908793 TI - Inhibition of human lysosomal elastase by the cartilage bone marrow extract Rumalon. AB - Human lysosomal elastase from polymorphonuclear leucocytes is inhibited by the cartilage bone marrow extract Rumalon. Separately, both the cartilage and the bone marrow extracts are able to inhibit the enzymatic activity by 73%, under saturating conditions. The mixture of the two extracts inhibits elastase by 93%. It is suggested that the two partners act as a cumulative inhibition mechanism and this phenomenon is emphasized in a general theoretical model for synergy of proteinase-directed inhibitors. PMID- 6908792 TI - [Activated C3 in the synovial fluid of patients with rheumatoid arthritis and arthrosis (correlations with C3, C4 and C3 proactivator/modification caused by storage)]. AB - Cleavage products of C3 in synovial fluid were determined by the method of 2 dimensional electrophoresis (Laurell). Statistically significant differences were observed in rheumatoid synovial fluid compared with the osteoarthrosis group. Storage is of crucial importance for the in vitro activation of C3. In fresh synovial fluid there was a significant positive correlation between breakdown products of C3 and C3, C4 and C3-proactivator. After storage (even in -70 degrees C) this positive correlation in the rheumatoid synovial fluid changes into a negative one. This phenomenon is not observed in synovial fluid from patients with osteoarthrosis. There is evidence that in the rheumatoid synovial fluid C3 activating fractions in 40S, 19S and 2,5S are responsible for the generation of C3 cleavage products. PMID- 6908794 TI - [Diagnostic and therapeutic problems in thoracic actinomycosis]. PMID- 6908795 TI - [Kallikrein-kinin system of the blood in acute cerebrovascular disorders]. PMID- 6908796 TI - Fletcher factor deficiency, source of variations of the activated partial thromboplastin time test. AB - The activated partial thromboplastin time test measures the integrity of the intrinsic clotting system. The sensitivity of this test to Fletcher factor deficiency is dependent upon the particular protocol and reagents utilized in the test system. The case report presented here demonstrates conflicting laboratory results obtained for a patient who had Fletcher factor deficiency, the results depending on the laboratory choice of test reagents. This serves to emphasize the importance of physician awareness of the procedures utilized in laboratory testing. PMID- 6908797 TI - A standard care plan for alcoholism. PMID- 6908798 TI - When the diagnosis is raynaud's. PMID- 6908799 TI - Temperature measurements in children. PMID- 6908800 TI - Second stage labor--has tradition replaced safety? PMID- 6908801 TI - Cimetidine update. PMID- 6908802 TI - A newborn's right to life vs. death. PMID- 6908803 TI - RN's experience in weight control prompts new venture. PMID- 6908805 TI - Yes, Virginia, nursing is a profession. PMID- 6908804 TI - Rain, rain, don't go away, Mommy wants to play. PMID- 6908806 TI - Living with cancer. PMID- 6908807 TI - How to increase compliance in hypertensives. PMID- 6908808 TI - Putting joint practice into practice. PMID- 6908809 TI - Dealing with feelings: handling depression by identifying anger. PMID- 6908811 TI - Nurses' reactions to restraining patients. PMID- 6908810 TI - Drugs and renal disease. PMID- 6908812 TI - The integrated curriculum: the emperor is naked. PMID- 6908813 TI - The advantages of part-time nursing. PMID- 6908814 TI - Seizure disorders. PMID- 6908816 TI - Surgical treatment of epilepsy. PMID- 6908815 TI - Seizure disorders. PMID- 6908817 TI - Complex partial seizures. PMID- 6908818 TI - Circulating and deposited immune complexes in patients with glomerular disease: immunopathologic correlations. AB - The presence of circulating immune complexes (ICs), and alterations of serum immunoglobulins G, A, and M, properdin factor B, and C3 and C4 levels were correlated with glomerular immune deposits in 50 consecutive renal biopsy patients. Urine from 25 of these patients was also examined for ICs. Agarose gel zone electrophoresis (AGE) was used for IC screening. This method detects greater than or equal to 200 ng of IC per 1.5 microliter sample application (approximately equal to 130 micrograms/ml of serum immune complexes) and gives some indication of antigen or antibody excess in the ICs. Glomerular immune deposits were detected by immunofluorescence and electron microscopy in 72% (36/50) of these patients. Circulating and/or urinary IC were found in 69% (25/36) of patients with positive immunofluorescence and 78% (11/14) of patients with negative immunofluorescence. Five of 11 patients with circulating IC but no renal deposition presented with idiopathic crescentic glomerulonephritis (ICGN). These results indicate that IC that persist in the circulation and/or pass renal glomeruli with minimal deposition may result in tissue injury. Circulating IC in antibody excess were detected in all patients with membranous glomerulonephritis. ICs were also found in 55% of patients with IgA nephropathy. Our observations support the hypothesis of an immune complex pathogenesis for these diseases. Determination of circulating and urinary IC in patients with glomerular disease may help in clinical assessment and provide information concerning the pathogenesis of these diseases in humans. PMID- 6908819 TI - Effects of freezing on the corneal stroma of the rabbit after keratophakia. AB - In three rabbits a keratophakia as described by Barraquer (1972) was performed on both eyes, in one rabbit it was performed on one eye. In the right eye no cryoprotective agent was used, in the left eye the cryoprotective agent KM 26 was applied. Twelve hours after the operation, the majority of keratocytes in the tissue lens were destroyed. The nuclear chromatin was clumped, the cell membrane was destroyed and cytoplasm showed vacuolar alteration; cell organelles were no longer recognizable. After 24 h hardly any keratocytes were found. All corneae operated on with and without a cryoprotective agent, showed the same morphology. The cell debris was removed by macrophages, which could be found earlier in corneae operated on without cryoprotection. Three weeks after keratophakia no increase in the number of the residual keratocytes had occurred. PMID- 6908820 TI - The post-mortem vacuoles of Schlemm's canal. AB - A two-part study was conducted in which post-mortem changes were investigated in the baboon outflow system. It was found that the meshwork cells closest to the chamber angle were particularly susceptible to post-mortem advance. Post-mortem vacuoles developed in the endothelium of Schlemm's canal and by light microscopy these structures could be mistaken for giant vacuoles. On the other hand it was shown by electron microscopy that the giant vacuoles which have been implicated in the transendothelial transfer of aqueous humour and post-mortem vacuoles were distinct and separate entities. PMID- 6908821 TI - Cellular composition of post-haemorrhagic opacities in the human vitreous. AB - The morphology of vitreous membranes from enucleated human eyes containing vitreous haemorrhage was studied by electron microscopy. Three types of membrane are described, based on their cellular composition: haematogenous, fibroblastic and neovascular. Simple vitreous haemorrhages usually failed to stimulate a fibroblastic cellular response, whereas vitreous blood clots in eyes with penetrating injuries were frequently invaded by choroidal and/or scleral fibroblasts. Fibroblast-like cells were also found in neovascular membranes, but not as a major cellular component. They had the appearances of astrocytes, suggesting an origin from the retina or optic disc in association with the intravitreal new vessel growth. These data suggest that two factors are necessary for intravitreal fibrosis: an adequate port of entry for cellular invasion and a suitable substratum on which migrating cells can crawl. PMID- 6908823 TI - An electron microscopic study of the epiretinal membrane of human eyes. AB - An electron microscopic study was conducted to elucidate the cell types involved in the formation of epiretinal membranes in four cases. In three cases, the specimens were provided by a vitrectomy and pigment epithelial cells (two cases) and fibrocytes (one case) represented the preponderant constituents of the membrane, whereas the membrane consisted chiefly of glial cells in the fourth case in which an eye showing this condition was obtained by enucleation. PMID- 6908822 TI - Qualitative observations on the variation of light induced damage to the rabbit retina. AB - The retinae of anaesthetised Dutch rabbits were exposed to light of various known intensities for one hour. Immediately after exposure the animals were killed and retinal and choroidal tissues were taken for investigation by electron microscopy from selected sited with the previously illuminated area. Initial qualitative observations suggested that a considerable variation in the degree of cellular damage had occurred even within retinal and choroidal tissues taken from the same eye. This variability of damage appeared to be related to intensity of illumination and patency of the choroidal vasculature. The mechanisms which could be underlying this variation of damage and possible methods of quantification are discussed. PMID- 6908824 TI - Regeneration of the human corneal endothelium. AB - The ability of the human corneal endothelium to regenerate is studied with the scanning electron microscope through examples of corneal diseases and penetrating keratoplasties. This study does not lead to final conclusions on the possibilities of regeneration of the human corneal endothelium but allows us to say that: --regeneration occurs through size increasing and deformation of the remaining cells. --the increase in number and size of surface microvilli may simply indicate a state of cell activation. --the presence of two nuclei in one cell is probably obtained by amitotic division but no complete mitosis has been seen. --Displacement of endothelial cells is a real progression and the cell is able to overcome obstacles. --the fibroblastic transformation of the endothelial cells is present in man but this may simply represent the migrating form of the cells. PMID- 6908826 TI - Attracting nursing students to the OR critical for future. PMID- 6908825 TI - Solid-phase immunoassay of dog neutrophil elastase. PMID- 6908827 TI - If nurses are treated like handmaidens, they may not stay. PMID- 6908829 TI - Implementing research in clinical settings. PMID- 6908830 TI - Speech patterns reflect power. PMID- 6908831 TI - Develop your skills at writing objectives for continuing education. PMID- 6908828 TI - Kerato refractive surgery: new horizon. PMID- 6908833 TI - Women's health risk expected to increase. PMID- 6908832 TI - Colombia's poverty poignant reminder to conserve resources. PMID- 6908834 TI - Nursing assertiveness in two cities. PMID- 6908835 TI - Collective bargaining: the American way. PMID- 6908836 TI - Clinical teaching and the nursing process-implications for nurse teacher education. PMID- 6908837 TI - Rationale, psychology, philosophy and reason for recreational activities for the frail aged. PMID- 6908838 TI - Why are there so few women in parliament? PMID- 6908839 TI - Do your meetings do any good? PMID- 6908840 TI - Rehabilitation engineering in Australia: future planning. PMID- 6908841 TI - Australian Council of Community Nursing. PMID- 6908842 TI - Assessment potential and limitations of rehabilitation-role of the nurse. PMID- 6908843 TI - Protein synthesis in pulmonary alveolar macrophages. Source of amino acids for leucyl-tRNA. AB - Extracellular, intracellular and tRNA-bound leucine pools of the adherent pulmonary alveolar macrophage were examined to determine the relationships between them and the precursor for protein synthesis. When cells were cultured in media of various leucine concentrations, the patterns of isotope distribution in intracellular and extracellular leucine did not correlate with the patterns seen in protein-bound leucine. hence, the free leucine pools cannot be used reliably as precursors for calculating rates of protein synthesis. tRNA-bound leucine, however, behaved isotopically as if it were the precursor. Constant synthetic rates were calculated using the tRNA specific activity over a wide range of leucine concentrations. In addition, by measuring the tRNA-bound specific activities of three different amino acids, leucine, valine and phenylalanine, and their respective specific activities in protein, we were able to calculate independently three separate but identical synthetic rates. At physiological amino acid concentrations, the macrophage intracellular leucine pool and the tRNA bound leucine pool received less than half of their amino acids from extracellular sources. At 5 mM external leucine, the intracellular specific activity was indistinguishable from that of the medium leucine, but the specific activity of the tRNA-bound leucine pool remained only about 50% that of the extracellular value. The most straightforward interpretation of why the tRNA bound leucine did not flood with external label under conditions where the intracellular pool has reached equilibrium is to propose that some portion of the leucine for protein synthesis is derived directly from protein turnover before the degradation products have mixed with the common amino acid pool. PMID- 6908844 TI - Vanadate and phosphate ions reduce tension and increase cross-bridge kinetics in chemically skinned heart muscle. AB - Tension development, immediate stiffness and ATPase of chemically skinned myocardial strips were measured in solutions with varying concentrations of phosphate (Pi) or vanadate (predominantly H2VO4 at pH 7) ion. Vanadate and Pi decreased stiffness in proportion to tension. The results show that, like Pi, vanadate accelerates the turnover rate of cross-bridges, but is effective at about 1/500 the concentration required for the Pi effect. Both Pi and vanadate increased the energy cost of isometric tension maintenance (that is, the ratio of ATPase to tension) and increased the velocity of delayed tension development following quick stretch of the chemically skinned myocardial strips. The results also show that changes in the rate of rise of delayed tension during stretch activation probably reflect changes in the kinetics of the biochemical cycle of the cross-bridges. PMID- 6908845 TI - The tissue response to exogenous elastase. PMID- 6908846 TI - Ultrastructural evidence of mucociliary function impairment induced by elastase. PMID- 6908847 TI - Characterization of different elastases. Their possible role in the genesis of emphysema. PMID- 6908848 TI - Prevention of elastase-induced experimental emphysema by a synthetic elastase inhibitor administered orally. PMID- 6908849 TI - Comparative effects of reversible and irreversible specific elastase inhibitors on elastase-induced emphysema. PMID- 6908851 TI - Modifications of 14C-glucosamine incorporation into hamster lung glycoconjugates in elastase induced emphysema. PMID- 6908850 TI - Elastase and lysozyme secretion by peritoneal macrophages: effects of dexamethasone and rifampin. PMID- 6908853 TI - Studies of kallikreins. V. Purification and characterization of rat intestinal kallikrein. PMID- 6908852 TI - Glycosaminoglycans in elastase induced emphysema. PMID- 6908854 TI - Some aspects on certain pathogenic agents in malaria. PMID- 6908856 TI - The penicillins. PMID- 6908857 TI - [Oral magnesium therapy in cases of preterm labour (author's transl)]. AB - 19 patients with preterm labour received an oral application of 20-30 mval/d Magnesium in addition to the common Fenoterol-Verapamil tocolysis. This therapy showed the following results: 1. augmentation of the Mg2+ serum level from 1.48 to 1.7 mval/l, 2. significant reduction of contraction frequency (p less than 0.005), 3. significant reduction of Fenoterol dose (p less than 0.005), 4. in 14 patients it was possible to change from parenteral to oral therapy. PMID- 6908859 TI - [The antepartum evaluation of pulmonary maturity in high risk pregnancies (author's transl)]. AB - In normal pregnancies the determination of the L/S ratio permits a reliable ante partum evaluation of fetal maturity. Good correlation between ante-partum determination and the condition of the newborn is obtained. In the 566 L/S ratios obtained from abnormal pregnancies the method was also reliable. There was 217 Rh incompatabilities, 51 pre-eclampsias, 31 diabetic patients, 112 premature labours, 78 placental insufficiencies and 77 premature ruptures of the membranes. In patients with diabetes the ante-partum diagnosis of pulmonary maturity is doubtful. In some patients with diabetes pulmonary maturity appears to be delayed. A difference between the abnormal pregnancies was not recognized. In the different types of high risk pregnancies no acceleration or retardation of pulmonary maturity was detected with statistical significance. However, in some cases of premature rupture of the membranes, premature labour and placental insufficiency, pulmonary maturity appears to be accelerated. PMID- 6908858 TI - [The cardiac situation of newborn children after long-term tocolysis with fenoterol (author's transl)]. AB - 516 newborn children were subject to a thorough cardiac and neurological test program after a long-term tocolysis with Fenoterol with and without a supplementary medication of Verapamil. No symptoms of a myocardial damage caused by the drug appeared neither in the electrocardiogram nor by means of lab chemical parameters such as CK-MB, Serum-Myoglobin and CK-B. Except for premature children, no significant neurological characteristics were found either. Due to the low quantity of Fenoterol passing through the placenta and based on the minimum cumulation of Fenoterol in the fetal tissue, especially in the fetal myocardium, a tocolysis does not seem to have any significantly dangerous fetal effects, if control parameters are strictly adhered to. The endeavoured therapeutical objective, namely the prevention of premature labour, thus justifies the application of the betasympathomimetic Fenoterol. PMID- 6908860 TI - [Comparison of different methods for estimating fetal weight by cephalo- and abdominometry (author's transl)]. AB - To check the accuracy of different published methods of fetal weight estimation based on head and abdominal parameters, all methods were used in every individual case in 123 pregnancies. It became apparent that the single methods gave the best results in different indications. As far as normal fetal development at term is concerned the best results were achieved by estimating the weight from the biparietal and the abdominal diameters whereas in macrosomy the prediction of fetal weight became much more precise in using head and abdominal circumferences. In premature and small-for-date infants, however, the best results were recorded if only the abdominal circumference was used for this reason reflecting the importance of the severe reduction in volume of the big parenchymateous organs of the abdomen. PMID- 6908855 TI - An evaluation of four methods for the measurement of elastase activity. AB - The precision of four different methods for the measurement of low levels of porcine pancreatic elastase was assessed using a synthetic substrate and by three other methods using the natural substrate elastin. The most precise method used the synthetic substrate Succ(Ala)3NA (within-batch coefficient of variation = 1.9%, between-batch coefficient of variation = 2.5%). Fluorescein-labelled elastin was the most precise of those methods using elastin as substrate (within batch coefficient of variation = 5.1%, between-batch coefficient of variation = 5.5%). PMID- 6908861 TI - [Is asymptomatic bacteriuria in pregnancy combined with pyuria? (author's transl)]. AB - The midstream urine of 269 pregnant women between 10 and 36 weeks gestation were investigated bacteriologically by the semi-quantitative dip method and microscopically for leukocytes in the urinary sediment. In 20 of 269 urines (7%) an asymptomatic bacteriuria was found but only in 10% of these bacteriurias leukocytes were found in the urine. An isolated pyuria without significant bacteriuria was found in 15 of 249 urines (6%). The assumption that a physiological pyuria exists in pregnancy was not substantiated. PMID- 6908862 TI - [The pathophysiology in treatment of asphyxia of the newborn (author's transl)]. AB - The pathophysiologic adaption mechanisms following perinatal asphyxia are a shock reaction with an integrated cardio-vascular reaction. For resuscitation of the newborn the therapeutic principle of ventilation with infusion resulting in perfusion is emphasized. The importance of sodium bicarbonate buffer treatment in primary resuscitation is discussed and the reasons for the limitation of their indication is explained by theoretical discussions and clinical findings. In closing the secondary (cerebral) resuscitation according to the multi-system reaction concept following perinatal asphyxia is discussed. This serves the treatment of functional changes in other subsystems especially the brain. PMID- 6908863 TI - [Clinical results of the treatment of ovarian carcinoma following 16 years of experience with the chemotherapy resistance test (author's transl)]. AB - A prospective study on the results of chemotherapy selected by the treatment chemotherapy resistance test of Limburg an Krahe (oncobiogram) of 191 cancers of the ovary from the same department from the years 1962-1978 is presented. In 152 cases (79.6%) surgical or radio-therapy was impossible or insufficient because of the advanced spread of the tumour (T4 of FIGO 3 and 4). Nevertheless in the hopeless state T4 Nx M1b (N = 89) a two years survival rate of 58% was obtained following the selective treatment according to the oncobiogram compared to 28% two years survival in blind chemotherapy. The five year survival rate was 38% compared to 18%. The total five years survival rate of all patients was 25% in a series with 80% inoperable cases. The advantages of chemotherapy following the oncobiogram with the chemotherapy resistance test compared to treatment after other testing methods or compared to blind chemotherapy are described and discussed in detail. PMID- 6908864 TI - [Aspiration cytology of the endometrium for the early diagnosis of carcinoma of the endometrium in its precursors (author's transl)]. AB - In 783 patients from age 38 to 83 aspiration cytology of the endometrium was carried out and compared to microscopic findings of the endometrium from the curettages. The samples were obtained from women with post-menopausal and pre menopausal bleeding and from women without bleeding prior to hysterectomy for various indications. In 49.% of the cases adenocarcinoma of the endometrium was detected, and in 4.2% of the cases pre-cancerous lesions such as adenomatous or atypical glandular hyperplasia of the endometrium and of the endocervix were observed. PMID- 6908866 TI - [Functional disturbances of the lower urinary tract following radical surgery for cervical cancer (author's transl)]. AB - 1972 to 1977 141 patients at the university department of gynecology and obstetrics in Innsbruck had radical abdominal hysterectomies according to Latzko because of carcinoma of the cervix uteri state I-IIa. 111 (78.8%) patients without recurrence of carcinoma were investigated without recurrence of carcinoma were investigated in the period of 2 to 36 months after operation in a modern urodynamic testing unit to state functional troubles of the lower urinary tract. We judged the sensibility of the bladder, the incidence of urinary incontinence, residual urine determinations and the frequency of infections of the lower urinary tract after radical hysterectomies. In particular we were interested in the urodynamic investigation (spontaneous flow rate and uroflow-metrie after bladder filling, liquid cystometry and simultaneous measurement of the pressure in the rectum for a faithful expression of the detrusor pressure). Based on these investigations we could indicate a typical type of troubles after radical abdominal hysterectomies, which partly depends on lesions of the autonomous nerval system of the lower urinary tract. 89.5% of all these patients within the first year after operation could not feel any desire to void although the bladder was full. Longer than one year after operation we could find the same symptom in 45.5%--recovery in part seems to be possible. Moreover we could find unnoticed urinary loss, residual urine and infections of the lower urinary tract (24.7%) in higher incidence compared with a control group. Because of our investigation we could work out advice for prevention and therapy of functional troubles of the lower urinary tract after radical abdominal hysterectomy. PMID- 6908865 TI - [The correlation between evidence of breast-cancer in the nipple and the axillary lymph nodes in cancer of the breast in women (author's transl)]. AB - In a random sample of 1,000 mastectomies from microscopically proven cancer of the breast the concomitant evidence of cancer in the nipple and the axillary lymph nodes were studied. Cases with evidence of cancer in the nipple showed axillary metastases twice as often as cases without evidence of cancer in the nipple. In cases with diffuse or lymphangetic evidence of cancer in the nipple the incidence of metastases in the axillary lymph nodes was twice as high in cases with intra-ductal or paget type evidence of carcinoma in the nipple. In cases with evidence of cancer in the nipple, the incidence of metastases in the axillary lymph nodes decreases more with age than in cases without evidence of breast cancer in the nipple. With increasing tumour size the evidence of breast cancer in the axillary lymph nodes was higher in cases without evidence of cancer in the nipple than in cases with evidence of cancer in the nipple. The microscopic differentiation and the grade of malignancy also had an influence on the incidence of axillary metastases in correlation to evidence of cancer in the nipple. PMID- 6908867 TI - [The importance of the long pelvis in clinical practice and medical education (author's transl)]. AB - The importance of the long pelvis with lumbo-sacral assimilation in obstetrics is evaluated. 111 x-rays of the pelvis in cases with abnormal deliveries were evaluated and compared to the clinical data. The incidence of the long pelvis was not increased in the total group, nor in the 100 cases with abnormal deliveries. A long pelvis was present in 30.2% of the 43 breech presentations. In 4 cases with a funnel pelvis vaginal delivery occurred without difficulty. In 42 posterior vertex presentation the long pelvis appears to have a pathogenetic importance regarding the primary posterior position. The further course of the delivery was not influenced by the long pelvis. In 7 cases of low transverse arrest, 4 had a long pelvis but only 1 had a funnel pelvis to explain this abnormal position. In summary, the long pelvis even in its most severe form, the funnel pelvis, does not block the adaptation processes in the lesser pelvis. The changes in the pelvic inlet due to the lumbo-sacral assimilation have an etiologic importance on the initial presentation at the inlet such as breech presentation, military vertex presentation, brow presentation, or Roederers anomaly. However, no prognostic value for the mechanism of the delivery can be derived from the initial presentation. The delivery dose not depend on the long pelvis but on the malpresentation when delivery becomes necessary. PMID- 6908869 TI - [Clinical study of the labour inhibiting effects an side effects of acetylsalicylic acid (ASA) (author's transl)]. AB - In 37 pregnancy women preterm labour was inhibited with intravenous administration of ASA. 20 patients (Group I) had a combined treatment of ASA and Fenoterol. 7 pregnant women (Group II) without successful labour inhibition under Fenoterol were treated with ASA subsequently. In a third group of 10 women we administered ASA alone. The treatment was considered as successful if signs of preterm labour stopped and pregnancy maintained for 7 days or more. In the first group 16, in the second group all patients had been treated successfully. In group III we succeeded in labour inhibiting for more than 7 days in 6 cases. An initial loading dose of 5.5 to 7.0 mn/min ASA had been infused for 24 hours. If preterm labour was stopped, the dosage had been reduced. In all patients dose related but reversible symptoms of vertigo, tinnitus, headache and hyperventilation were seen. Furthermore we found a non-dose-dependent prolongation ( by 30% or normal) of bleeding time. In the fetus respectively the newborn an affection by this ASA treatment could be excluded. We propose inhibition of preterm labour by i.v. ASA administration in all pregnant women if beta-mimetic drugs are not successful or an intolerance is diagnosed. Contraindications for ASA therapy are mentioned. PMID- 6908868 TI - [Improved diagnosis of pregnancy-associated gynaecological emergencies via rapid beta-HCG test (author's transl)]. AB - A pregnancy-related disorder was identified by a rapid radioimmunoassay or serum chorionic gonadotropin in 151 out of 600 women (25%) with lower abdominal pain or bleeding, while a routine pregnancy test in urine was positive in only 7% of these cases. In 60 patients with ectopic pregnancy the rapid hCG-RIA was positive in 90% as compared with 10% for the routine pregnancy test. In patients with evidence of intrauterine pregnancy (80 cases) the rapid hCG-RIA was positive in 99% and routine pregnancy test in 39%. The clinical sensitivity of the hCG-RIA was 95%, specificity 96% and predictive value 88%. These figures should introduce a considerable improvement in the routine diagnosis of early intra- and extrauterine pregnancy-related disorders. PMID- 6908870 TI - [Possibilities of ultrasonic examination of the mammae (author's transl)]. AB - 1,344 women were examined in the course of 3 years by means of the ultrasonic system Multiplanar MS 3 which was coupled direct to the skin. This direct coupling to the skin of the breast and the freely mobile sound head enable immediate puncture of tumours of the breast in direct ultrasonic vision. In multiple cysts it will be possible to puncture all cysts--including the occult ones--in one session. In the first 229 examined tumours, the rate of accuracy of the diagnosis "cyst" was 98%. Successful punctures, including the non-palpable cysts, were effected down to a minimum volume of 0.1 ml. The problem of the nonpalpable cysts can be considered as solved from the sonographic angle. In our case, this entailed omission, and hence saving in cost, of every third biopsy of the mammae (approximately 200 out of 600 biopsies per annum). PMID- 6908871 TI - [On-target accuracy of tumour punctures in the breast. Possible sources of error in puncture cytology (author's transl)]. AB - Puncture cytology can yield false results if the tumour to be explored is not definitely located by the puncture needle. The risk of missing the tumour is particularly great if the tumour is small. We do not know of any safe method to control and ensure on-target accuracy. In the course of 3 years we punctured in 203 women 665 palpable and also non-palpable cysts, using compound scanner Multiplanar-MS-3. 38 further individual punctures failed despite repeated attempts under visual control of this device which supplies a spatial impression of the target during puncture. Some of the small tumours will evade the advancing needle time and again. PMID- 6908872 TI - [Microcalcifications in mammography and visualization by ultrasound (author's transl)]. AB - Sonography can yield indirect visualization only of microcalcifications in the female breast. In order to obtain an image of the echo pattern of the grouped microcalcifications, it is essential that the device employed possesses suitable dynamic characteristics, and it is also necessary to employ the technique of additive tomography. The investigator must familiarize himself with the proper interpretation of reflex patterns. Microcalcifications cannot be detected via sonography with the same degree of accuracy as with the help of mammography. However, sonographic detection is easier if the microcalcifications are more closely grouped. Nevertheless, the authors were able to show in a small comparative series that grouped calcifications can be detected even without previous information of their presence. PMID- 6908873 TI - [The effectiveness and ultilization of screening cytology for cervical cancer in the Federal Republic of Germany (author's transl)]. AB - The mortality from invasive carcinoma of the uterine cervix in the Federal Republic of Germany decreased from 1970 to 1977 in the age group 35 to age 59, between 19% and 28% in an age standarized study. A correlation with the introduction of the universal screening cytology in 1971 is highly probable. The utilization of the screening program in the age group of 30 to 60 years is 40- 50% of the eligible women. At 2 year intervals the utilization is 55%. The utilization be senior citizens is only 25%. The number of women screened in the most important age groups is higher than usually quoted in the German literature. PMID- 6908876 TI - [A report about 311 ovarian carcinomas, treated at the "Universitats-Frauenklinik des Klinikums Mannheim der Universitat Heidelberg" from 1960--1978 (author's transl)]. AB - In the medical histories no hints could be found, suggesting a definite risk group for ovarian carcinoma. Symptoms and complaints are often uncharacteristic and no methods for early recognition are known. The therapy of the ovarian cancer is an operation, combined with chemotherapy, or radiation considering to the stage of the tumour. Most important for the prognosis is the degree of expansion, besides age of the patients and the histological pattern of the tumour. The three years-survival rate of our patients with stage T1 is 71,7%, and with stage T4 only 13,5%. Above all advance in early diagnosis it is necessary to achieve higher survival rates. PMID- 6908874 TI - [Colposcopy and early changes of cervical carcinoma (author's transl)]. AB - Cytology and colposcopy are well recognized methods in the early diagnosis of pre malignant and early invasive changes of the uterine cervix. Since 1971 the University Department for Women in Leipzig has a cytology clinic. The results of repeat smears before biopsies and the follow-up examinations on 202 cone biopsies are reviewed. The incidence of negative findings decreases with increasing atypia of the squamous epithelium. The highest incidence of false negative smears was 73.3% in mild and moderate dysplasias. The more pronounced the atypia the smaller is the number of inadequate pap smears. In cases with negative cytology and colposcopic atypia the colposcopic findings must be clarified. Only the combination of colposcopy and cytology leads to optimal early diagnosis of cervical intra-epitheal neoplasia and invasive carcinoma of the cervix. The false positive cytosmears in the screening are discussed and a treatment with estrogens prior to repeat examination is recommended. Diagnostic problems arise from a discrepancy in the colposcopic and cytologic findings. Discrepancies depend on the colposcopic experience of the examiner. Improvement of the colposcopic diagnosis is obtained by directed colposcopic biopsy. PMID- 6908875 TI - [High-dosage gestagen long-term therapy in corpus carcinoma; influence on survival time (author's transl)]. PMID- 6908877 TI - [Bilateral ovarian carcinoma during pregnancy (author's transl)]. AB - A case of bilateral ovarian carcinoma during pregnancy is reported. The diagnosis was obtained at 18 weeks gestation by laparoscopy and bilateral salpingo oophorectomy with excision of macroscopically evident tumour was carried out. The gravid uterus was retained because of the high desire for childbearing of the 27 year old primirgravida. At 39 weeks gestation the pregnancy was terminated by Cesarean section and a small retrouterine metastasis were excised. Post-partum a single agent chemotherapy with Cyclophosphami was started. Eight years later mother and child are in good condition. The treatment of this case is compared to reports from the literature. PMID- 6908878 TI - [A retrospective study of 211 twin births (author's transl)]. PMID- 6908880 TI - [Medical accuracy in the decision: forceps versus cesarean section]. PMID- 6908879 TI - [Twins--intra- and extrauterine alive at term (author's transl)]. PMID- 6908882 TI - [Artificial insemination with donor semen in gynaecological office practice (author's transl)]. AB - Artificial insemination with donor semen (AID) is by no means rare in present gynaecological office practice. When fresh semen is used the success rate is satisfactory. 64 women were treated, 47 patients became pregnant. 4 women conceived twice. There were 3 pairs of twins in 51 pregnancies. Of the 64 treated women 3 had an early abortion. One of these patients conceived a second time and had a term delivery of a healthy infant. The abortion rate was around 4% and therefore much less than the comparable abortion rate of 13.5% in series with frozen semen. The 47 mothers had 51 healthy newborns within 66 months. The success rate was approximately 75% for the 48 term pregnancies in the 64 treated patients. This success rate is better than that quoted by Bergman of 38%. The mean age of all pregnant women was 30.02 years. The mean age of women which required additional hormonal therapy was 32.09 years, the mean age of pregnant women without hormonal therapy was 28.45 years. PMID- 6908881 TI - [Notes on sexual development and sexual behaviour of sterile marriage partners (author's transl)]. AB - Criteria which are essential for sexual development were examined on the basis of interviews conducted with 57 married couples who had remained without children without wanting to be childless, the reasons for their sterility being different in each case. It appears that both the experience of the first cohabitation and of the first orgasm, as well as the number of sexual partners before marriage are in some way connected with subsequent infertility. We also attempted to examine marital sexual relations in a kind of stock-taking operation. The cumulative occurrence of disturbances of intimate life was confirmed by this study, especially the reduced sexual satisfaction which depends on the cause of sterility. It also appears that changes in libido and feeling are influence by fertility; however, relative increases in such changes seem to indicate psychosexual disturbances of maturity in some of the partners, from which it would be possible to derive causal connections with infertility and therapeutic approaches. PMID- 6908883 TI - [Obligation of presence of the obstetrician in the delivery room]. PMID- 6908884 TI - Complement increases in experimental Leishmania donovani infection of the golden hamster. PMID- 6908885 TI - Our power to become. PMID- 6908886 TI - Introduction: chronic ventricular arrhythmias--a major unresolved health problem. PMID- 6908887 TI - The electrophysiologic basis for cardiac electrical activity: normal and abnormal. AB - The participation of several more-or-less independent electrophysiologic and structural phenomena may be required to generate and maintain a cardiac arrhythmia. Until these phenomena are better understood, therapy of these disorders will remain largely empirical. PMID- 6908888 TI - The Wolff-Parkinson-White syndrome--diagnosis and treatment. PMID- 6908889 TI - Editorial: Enzymes in the diagnosis of myocardial infarction. PMID- 6908890 TI - Diagnostic assessment of myocardial infarction based on lactate dehydrogenase and creatine kinase isoenzymes. PMID- 6908892 TI - Types of preventive health cues given to high-risk individuals. AB - Nineteen hospitalized patients with CAD were questioned about the types of preventive health recommendations they received during the 5 year period prior to development of symptomatology. Types of patient-practitioner interactions (egalitarian or dependency) were also investigated to assess consumer attitudes toward physicians and professional nurses as providers of preventive health and/or health maintenance services. The following conclusions were drawn in relation to the study population: (1) Health practitioners are, in many cases, identifying individuals at risk for developing CAD but they often fail to identify all pertinent risk factors and to give appropriate preventive health recommendations, and (2) there is consumer support for expanding the role of the nurse in the delivery of preventive health care and in the management of chronic illnesses. PMID- 6908891 TI - Prevention and treatment of pulmonary complications in patients after surgery of the upper abdomen. AB - Pulmonary complications are the leading cause of morbidity and death during the postoperative period in patients who have undergone upper abdominal surgery. Significant pulmonary mechanical alterations, such as reductions in VC, TV, and FRC and an increase in CV, are noted postoperatively in this patient population. Preexisting patient conditions, postoperative treatments, and certain respiratory maneuvers may increase the patient's risk in the development of postoperative pulmonary complications. Current research unanimously advocates sustained maximal inspiration, the normal physiologic sigh maneuver, as the best method of prevention and treatment of this problem. Commonly utilized maneuvers, such as blowing into a rubber glove or bag, blow bottles, and the like, should be avoided in all situations. A guide for preoperative and postoperative pulmonary assessment and care based on current research is included. After consideration of the data in addition to personal clinical experience, I conclude that to prevent pulmonary complications in patients after upper abdominal surgery, as well as in all hospitalized patients, sustained maximal inspiration, preferably with an incentive spirometer, and conscientious nurse supervision and coaching is the method of choice. PMID- 6908893 TI - Grand rounds in critical care: Problems in swallowing and esophageal carcinoma. PMID- 6908894 TI - Acute myocardial infarction and left bundle branch block. AB - Complete left bundle branch block often masks old as well as acute myocardial infarctions. However, a diagnosis of acute myocardial infarction in the presence of complete left bundle branch block can be made when the acute injury current is large enough to modify the secondary repolarization abnormalities of left bundle branch block. Under these circumstances the classical ST-T changes of an acute infarction may evolve in serial electrocardiograms. PMID- 6908896 TI - The use of monitoring technicians. PMID- 6908895 TI - Calculating dosage determination and delivery when using vasoactive drugs. PMID- 6908897 TI - The effect of aging on urinary kallikrein excretion in normotensive subjects and in patients with essential hypertension. AB - The effect of aging on urinary kallikrein excretion (UkalV) was investigated in 54 normal subjects, 11-88 yr old, and 37 patients with essential hypertension, 17 82 yr old. Urinary sodium, potassium, and aldosterone excretion (U(Ald)V) were also measured in these subjects. Urinary sodium and potassium excretion in both normal subjects and hypertensive patients did not significantly change with aging. In normal subjects, U(kal)V (r = 0.45; P less than 0.001) and U(Ald)V (r = 0.58; P less than 0.01) significantly decreased with increasing age. U(kal)V was positively correlated with U(Ald)V (r = 0.44; P less than 0.001). In contrast, the hypertensive patients had a significant decrease with age in U(Ald)V (r = 0.36; P less than 0.05), but no significant age-related change in U(kal)V. No significant correlation between U(kal)V and U(Ald)V was observed in the hypertensive patients. In individuals less than 60 yr old, there was no significant difference in U(kal)V values between normal subjects and hypertensive patients. Hypertensive patients more than 60 yr old excreted more urinary kallikrein than normal subjects of the same age group (P less than 0.05). In conclusion, the age-related decrease of U(kal)V in normal subjects may be due to the reduced activity of the renin-angiotensin-aldosterone system. It remains to be elucidated whether the absence of the age-related decrease in U(kal)V in hypertensive patients is related to the pathogenesis or pathophysiology of essential hypertension. PMID- 6908900 TI - The selection of students for health visitors training courses. PMID- 6908899 TI - Cleansing incontinent patients: an evaluation of the use of non-ionic detergents compared with soap. PMID- 6908898 TI - Emergence of gentamicin- and methicillin-resistant Staphylococcus aureus strains in New York City hospitals. AB - Gentamicin- and methicillin-resistant strains of Staphylococcus aureus have been isolated from Spring 1979 to the present from many hospitals in New York City. A large proportion of the strains were resistant to the majority of antistaphylococcal antibiotics. The ratio of multiply resistant strains was highest among tetracycline-resistant strains. There were significant differences in phage susceptibility patterns and the resistance spectrum of strains isolated at different hospitals, whereas strains isolated at the same hospital often showed a marked degree of similarity. This suggests multiple origins of gentamicin- and methicillin-resistant strains isolated in New York City. PMID- 6908901 TI - Perspectives on attitudes to nursing in Australian nursing students. AB - At a hospital school of nursing in Australia, a pilot study was carried out on first year students' images of nursing and work values. Students were found to accept most items on the College of Nursing (Australia) Inventory as characteristics of nursing and as work values. Background factors had minimal effect on their attitudes to nursing and work values, although age, type of secondary school attended, and religion had minor effects. Responsibility for decisions, individuality, job security, maintaining personal identity, and flexibility, were more highly rated as work values than as characteristics of nursing. No difference between students with and without previous psychiatric nursing training was found on the attitude scales. Limitations of the study and suggestions for further research are discussed. PMID- 6908902 TI - A study of the nurse tutor's role. AB - The aim of the study was to determine how British nurse tutors and nurse learners perceive the role of the nurse tutor in the field of general nursing. A survey by questionnaire was the method of inquiry used. The sample was drawn from eleven schools of nursing in one Regional Health Authority in England, and comprised 317 nurse learners and 93 nurse teachers. Data from the questionnaires were analysed using the statistical technique of factor analysis. In particular the learners' data were used to derive factor scales relating to aspects of the role of the nurse tutor. Twelve such factor scales emerged from the factor analysis of the data. Agreement was found between the learners and the teachers on four of these factor scales and disagreement was found relating to the remaining eight. It is suggested that the areas of agreement might form the basis for the systematic description of the role of the nurse tutor. Conversely, the areas of disagreement could provide a basis for further research into this subject. PMID- 6908903 TI - From task assignment to patient allocation: a change evaluation. PMID- 6908905 TI - The health dimension in nursing practice: notes on nursing in primary health care. PMID- 6908904 TI - Bridging the gap: liaison between nursing education and nursing service. AB - The integration of nursing education and nursing practice is a problem of both the British system and the North American system. Liaison between educators and service staff is often difficult. Between December 1977 and December 1978 informal observations were made at a London teaching hospital and three Scottish colleges of nursing, to determine how much liaison actually occurs between education and service. Some organizational literature gives pointers to ways education and service may be integrated. The British and North American systems are contrasted to highlight some of the differences and similarities of the systems. The integration of theory and practice is perceived as a cycle, effective nursing care leading to good learning experiences, and effective education leading to effective nursing care. The paper indicates areas for further study and approaches to solving the problems. PMID- 6908906 TI - Territoriality as a universal need. AB - Three aspects of territoriality are important to consider when planning nursing care: a physical space of one's own, a personal space, and the territory of expertise or role. Territoriality serves four functions: it provides security, privacy, autonomy, and self-identity, all of which are important for well-being. Many factors, such as age, sex, culture, and health status, affect the way people relate spatially to one another. The nurse should assess territorial needs routinely by asking the patient questions and by observing him in his environment. If the patient is in his own home, she should avoid invading his territory without his permission and should help him maintain and protect his territory. If the patient must leave his own home to be hospitalized, she should help him establish a temporary territory elsewhere and help him adapt to the loss of his own physical space, personal space, and/or territory of expertise and role. Careful attention to territorial needs, particularly when the person is ill, at a vulnerable age, or is facing a move, can contribute a great deal to his health and well-being. PMID- 6908907 TI - An overview of evaluation research in nursing. PMID- 6908908 TI - Ward orientation training with psychogeriatric patients. PMID- 6908909 TI - The effect of instruction on control of blood pressure in individuals with essential hypertension. AB - This exploratory study examined the effect of structured teaching about essential hypertension on control of the diastolic blood pressure in individuals with a diagnosis of essential hypertension. Using the pre-test, post-test design, study participants were measured on knowledge about essential hypertension and diastolic blood pressure before and after intervention. Six hypotheses were tested, three related to control of blood pressure, and three related to knowledge about essential hypertension. There was no significant difference between the experimental and control groups on diastolic blood pressure readings at the conclusion of the study. There was a significant difference between the experimental and control groups on post-test scores on knowledge of essential hypertension. It was concluded that structured teaching had no significant effect upon control of the diastolic blood pressure. Instruction increased knowledge, but not blood pressure control. PMID- 6908911 TI - Antibody that recognizes total human urinary kallikrein: radioimmunological determination of inactive kallikrein. PMID- 6908910 TI - On localization of kallikrein in the human pancreas and salivary glands by direct immunofluorescence. PMID- 6908912 TI - Measurement of kallikrein activity in urine of rats and man using a chromogenic tripeptide substrate. Validation of the amidolytic assay by means of bradykinin radioimmunoassay. AB - Urinary kallikrein activity in rats and man was measured by an amidolytic assay using the chromogenic tripeptide D-valyl-leucyl-arginine-p-nitroanilide (S 2266). The sensitivity of the assay permits the measurement of 3.5 to 250 mKU of purified porcine pancreatic kallikrein. The intraassay coefficient of variation was 1.6 +/- 0.3% and the interassay coefficient of variation 7.4 +/- 0.9%. No changes in kallikrein activity was found in urine samples kept for 7 days at 4 degrees C for 14 months at -20 degrees C. Repeated freezing and thawing reduced kallikrein activity. Kallikrein activity of the same urine samples was also estimated by means of a bradykinin radioimmunoassay, which determines the kinins released during incubation of urine with partially purified dog kininogen (kininogenase activity). The urinary kallikrein activity assayed by means of these two methods showed a high correlation with coefficients of r = 0.9134 for rat urine (p less than 0.0001) and r = 0.8002 for human urine (p less than 0.001). PMID- 6908913 TI - Antibiotic therapy of serious Haemophilus infections--a continuing problem. PMID- 6908915 TI - Childbirth education in 1980. AB - A questionnaire was developed to elicit information from childbirth educators regarding their preparation; their clients; their business arrangements; and their opinions on class content, national guidelines, and certification. From 776 questionnaires mailed, 238 usable responses were obtained. Persons of varing backgrounds enter childbirth education through a variety of routes, practice in a variety of settings, and use varied content. A majority agree that there is a need for national guidelines for preparation and content. PMID- 6908914 TI - Renal vascular and tubular effects of vanadate in the anesthetized rat. AB - The purpose of these experiments was to establish the renal vascular and tubular effects of vanadate. Three groups of adult rats were anesthetized with Na pentobarbital and given an i.v. infusion of a physiological saline solution at 0.055 ml/min. After a 60-min equilibration period, mean arterial blood pressure was measured, as were clearances of para-amino-hippuric acid (CPAH) and inulin (Cin), urine flow (V) and osmolality (Uosm) and the excretion rates of Na (UNaV), of K (UKV) and of Ca (UCaV). After the initial measurements, the i.v. infusion of physiological saline was continued in group 1 (controls), while vanadate was added to the saline and infused at 0.07 and 0.14 microM/min in groups 2 and 3. Then, all measurements were repeated. Compared with the control group, the following dose-dependent changes were observed in the vanadate-infused rats: increased mean arterial blood pressure, decreased CPAH (effective renal plasma flow), decreased Cin (glomerular filtration rate), increased V, UNaV and UCaV and decreased Uosm and UKV. Both the renal vascular and renal tubular effects of vanadate are similar to the renal effects of ouabain, previously reported by others. These effects can be explained by inhibitory effects of vanadate on Na,K adenosine triphosphatase (ATPase) and/or Ca/ATPase activities of renal vascular and tubular cells. PMID- 6908916 TI - Continuous fetal tissue pH monitoring. A preliminary experience. AB - Measurement of fetal scalp pH can aid in the detection of fetal acidosis. In order to evaluate fetal status further and possibly reduce fetal and neonatal mortality and morbidity, as well as reduce unnecessary cesarean section, continuous assessment of fetal pH is being investigated. Discussion of a six month experience with a continuous + pH scalp electrode and monitor is presented, together with results of the limited study, as well as specific nursing action appropriate to an invasive method of research. PMID- 6908917 TI - Initial mothering patterns of low-income black primiparas. AB - Observations at three separate intervals of 24 black, low-income primiparas revealed that there is not necessarily a progressive use of the mother's fingers, hands, and arms during the attachment process. Although the mothers did use fingertips to explore their new infants at some time during the first contact, this was not their immediate behavioral responses as defined by Rubin as well as Klaus, et al. The orderly sequence from fingertip exploration to encompassing behavior has been noted by Rubin to occur over a period of time. Klaus reports the interval to be only days. The mothers in this study exhibited encompassing behavior immediately by reaching out for their infants using both hands and arms. The majority held and looked at their new babies throughout the contact time indicating the instinct for the en-face position which Klaus, et al. have described so clearly. The study data would also support Perry's statement that eye contact is an indicator of the intensity of the mother-infant interaction. Over one-half of the subjects, during the first contact, initiated verbal response to their infants. None, however greeted their infants by using given names. Clark, Affonso, and Harris do not refer to the significance of identification of baby by the mother, only to verbal interaction. All mothers in the study made positive statements regarding their infants's appearance and behavior which compares exactly with findings of Robson and Moss. PMID- 6908918 TI - The older primipara: implications for nurses. AB - The professional nurse plays a major role in counseling the older couple throughout the pregnancy, labor, delivery, and puerperium. Nurses need to keep abreast of the new testing and monitoring procedures used during pregnancy and labor and delivery, and these procedures need to be explained to the pregnant couple. Individual and group teaching are ways that the nurse can counsel and support the older couple, thereby increasing their confidence in the health team and their ability to incorporate a child into their lifestyle. In this article these concerns are addressed as related to 1) physical needs and 2) psychological needs. PMID- 6908919 TI - Nursing care of the pregnant woman with diabetes mellitus. AB - The woman with diabetes who becomes pregnant faces increased risk of morbidity, urinary tract infections, vaginitis, difficult delivery, hemorrhage, cesarean section, preeclampsia, and hydramnios. Chronic disease alone produces emotional tension. Added to this she has increased general life stresses such as added financial responsibility, increases time commitments, and changes in lifestyle demands. The infant of the diabetic is often large for dates, faces respiratory distress syndrome with early delivery, may experience hypoglycemia, and may have fetal anomalies. Clinical specialists of nursing, consulting and working together, can develop a plan of nursing care for the pregnant woman with diabetes. Because the pregnant diabetic woman faces the usual adjustments to pregnancy plus problems dealing with a chronic condition of diabetes, nursing care should combine consideration of the physical, emotional and educational needs. In view of the many health team members providing care to the pregnant diabetic, one central figure with continued interaction can decrease fragmentation and provide continuity of care. PMID- 6908920 TI - Developing a community-based parent education support group. PMID- 6908921 TI - Breastfeeding and the working mother. PMID- 6908922 TI - Family mental health care in the neonatal intensive care unit. PMID- 6908923 TI - Pelvic examination of children. PMID- 6908924 TI - Fetal monitoring. PMID- 6908925 TI - Sex education in the public schools. PMID- 6908926 TI - It isn't sex education unless. PMID- 6908927 TI - Putting sex education in its place. PMID- 6908928 TI - The case for a moral sex education in the schools. PMID- 6908930 TI - The Falls Church experience. PMID- 6908929 TI - Family life and human development (sex education): the Prince George's County Public Schools experience. PMID- 6908931 TI - Sex and society: teaching the connection. PMID- 6908932 TI - Coordinating and planning for human sexuality education. AB - The coordinator provides parent education, teacher and staff inservice training, team-teaching experiences, student counseling and a broad range of support activities related to the wider community as well as to the schools involved. The need for a coordinator for programs may depend on size and/or diversity of the school population, professional readiness of teachers and types of programs to be implemented. Despite the advances made in the Pomona program, there continue to be such problems as occasional resistance from special interest groups, administrators and school staff, individual instructors' personal value conflicts, transitional nature of student population and turnover in teacher personnel. A coordinator for sexuality programs is certainly not a total remedy for such problems in all school districts; but as an essential element in the solution of those problems, he/she provides an approach which will help school districts in initiating and implementing programs with a greater degree of success. PMID- 6908933 TI - STD education: challenge for the 80s. PMID- 6908935 TI - Teacher training for sex education. PMID- 6908936 TI - Developing community support: a first step toward a school sex education program. PMID- 6908934 TI - Starting family life & sex education programs: a health agency's perspective. PMID- 6908937 TI - The PTA's health education project and sex education in the schools. PMID- 6908938 TI - Adolescent sources of information on sex. PMID- 6908939 TI - Evaluation in sex education: evaluation research for sex education applied to program planning. PMID- 6908940 TI - Planning school based sexuality programs utilizing the PRECEDE model. PMID- 6908942 TI - Mandated family life education a rose is a rose is a rose is a rose. PMID- 6908941 TI - Teacher characteristics and the inclusion of sex education topics in grades 6-8 and 9-11. PMID- 6908943 TI - Difficulties in implementing sex education--the Nevada experience. PMID- 6908945 TI - The SIECUS/New York University principles basic to education for sexuality. PMID- 6908944 TI - The new opposition to sex education: a powerful threat to a democratic society. PMID- 6908946 TI - Complement proteins and macrophages. III. The production of factor B by particle ingesting macrophages. AB - A kinetic study of factor B secretion by particle-ingesting macrophages showed that the ingestion of zymosan but not latex lead to an early suppression of factor B secretion followed by a significant enhancement. This dual response was proportional to the number of ingested zymosans. After a suppressive period of 24 48 hr, the ingested zymosan stimulated the synthesis of factor B. The response of acid phosphatase synthesis to ingested zymosan was the same as that of factor B, while the synthesis of lactic dehydrogenase proceeded without an early suppression. These results suggest that factor B should be considered an enzyme released into the lysosomes of macrophages. PMID- 6908947 TI - Structure and incentive problems in economic regulation of medical care. AB - Health-care markets, characterized by unusual structures and incentives, are less effectively influenced by direct economic regulation than are other markets. Command-and-control economic regulation may contain costs but to the detriment of access, efficiency, innovation, and responsiveness to consumers. Market reform strategies offer a sound and feasible policy alternative. PMID- 6908948 TI - Competition and health cost containment: cautions and conjectures. AB - Market approaches based on reformed incentives and newly vigorous competition are increasingly proposed as reliable, preferable alternatives to public regulation in the quest for health care cost containment. Health maintenance organizations (HMOs) are often said to provide both theoretical and empirical support for market approaches and are expected to be important vehicles for the exercise of market forces in a "reformed" health care system. Yet experience in the 1970s with federal efforts to increase the number and enrollment of HMOs suggests that serious problems of organization, expectations, and political interest will arise even in a reformed marketplace. PMID- 6908949 TI - Altering the tax treatment of employment-based health plans. PMID- 6908950 TI - The essential role of antitrust in a competitive market for health services. PMID- 6908951 TI - On public values and private regulation: some reflections on cost containment strategies. PMID- 6908953 TI - A nurse's view of Soviet psychiatry. PMID- 6908952 TI - A model for advanced nursing preparation in chronic psychiatric care. PMID- 6908954 TI - The day hospital on state hospital grounds: paradigm of cooperation. PMID- 6908955 TI - The developmental phases of the nurse/resident relationship on an in-patient psychiatric unit. AB - We have identified four developmental phases of the nurse-resident relationship during a six month residency rotation. The first phase is the "Honeymoon Phase," characterized by the nurse and resident working together to maintain superficial harmony. The second, or "Testing Phase," raises issues of trust and control which must be resolved before the more collaborative team work characteristic of the "Cohesive Phase" may begin. The third, or "Cohesive Phase," is a period of sharing in which the nurse and the resident have developed trust in one another's abilities. Finally, during the "Separation Phase," the nurse must identify and resolve her own feelings about the resident's upcoming departure. When the nurse has successfully resolved these feelings, she is then in a position to reinvest her energies in the initial stages of another nurse-resident relationship. The nurse's awareness of developmental phases and their respective developmental tasks fosters her objectivity and ability to define specific professional goals. PMID- 6908956 TI - Communicating clinical nursing issues through the newspaper. AB - The information quality of nursing news is a critical factor in gaining public support for the acquisition of scarce resources necessary to undergird clinical nursing practice. A content analysis of 3,098 newspaper articles about nursing in 1978 was employed to examine the treatment of clinical nursing news. Among the variables studied were practice settings, educational levels, role clarity, professional activities, nurse-physician relationships, and degree of favorable image. Results revealed that the quality of news about clinical nursing varied by specialties, with maternity nursing and pediatric nursing news shown to be more progressive and community health nursing and medical-surgical nursing revealed as quite traditional. Psychiatric nursing received an inordinately low level of news coverage. Recommendations are offered to assist improvement in the amount and quality of news treatment of clinical nursing. PMID- 6908957 TI - A validation study: simulations as a measure of nurse practitioners' problem solving skills. AB - A national sample of 79 masters- and certificate-prepared family and adult nurse practitioners completed six instruments designed to validate one type of clinical simulation, patient management problems (PMPs). The instruments were: a self chart audit, self-evaluation rating scale, colleague evaluation rating scale, multiple-choice examination. PMP simulation, and demographic questionnaire. Use of a multitrait-multimethod correlation matrix, a multivariate analysis of covariance, and a stepwise multiple regression analysis provided modest evidence to support the claim that the PMP simulation is a valid measure of the construct clinical problem solving. In fact, a multiple-choice examination appeared to be an equal, if not superior, instrument. PMID- 6908959 TI - Trace anesthetic vapors in hospital operating-room environments. AB - This study investigated concentrations of halothane anesthetic vapors in the operating rooms of two hospitals in the Ottawa, Ontario, Canada, area. Air samples, taken by active charcoal tubes and dosimeter badges, were analyzed by a gas chromatographic technique. Readings of 71 samples taken from hospital A and 65 samples from hospital B ranged from 1.0 to 29.4 parts per billion (ppb) for the active period and 0.1 to 3.8 ppb for the inactive period. All samples showed trace concentrations of halothane, but were well below the recommended maximal level. PMID- 6908958 TI - Effect of information on emotional responses during barium enema. AB - A quasi-experimental study was conducted to extend: 1) Johnson's findings by using a measure of anxiety proneness to control for individual variations in responding to stressful situations and 2) the applicability of Johnson's work to another procedure, barium enema. The subjects, 24 hospitalized patients, were assigned to one of three information conditions: sensation, procedure, or no information. Prior to the barium enema all subjects took the trait portion of Spielberger's State-Trait Anxiety Inventory to measure relatively stable individual differences in anxiety proneness. Two groups heard a taped measure of sensation or procedural information; the third group heard no information. After the barium enema, all subjects took the state portion of the State-Trait Anxiety Inventory to measure emotional responses during the barium enema. Subjects who received sensation information reported less anxiety than subjects who received no information or procedural information. However, the hypothesized relationships between the mean state anxiety scores for the three information groups were not found. PMID- 6908961 TI - How nursing students' reactions to rape victims are affected by a perceived act of carelessness. AB - This experiment focused on how reactions to a rape victim would be affected by a perceived act of carelessness. The subjects were 116 graduating baccalaureate nursing students, 31% of whom were registered nurses. All subjects read a vignette of a rape in which the victim was described as having driven to a drugstore on a legitimate errand. Subjects were randomly assigned to read one of four versions, in which the victim either locked or failed to lock her car door (carelessness manipulation) and in which the rape occurred at 10:00 P.M. or midnight. All subjects evaluated the victim on a series of 11-point rating scales, and the data were analyzed by means of 2 x 2 analyses of variance. As hypothesized, subjects in the unlocked condition (compared to those in the locked condition) liked and identified with the victim significantly less, and attributed significantly more carelessness and responsibility for the rape to her. There was no significant main effect for the time the rape occurred. Use of vignettes as an unobtrusive measure of attitude toward rape, and implications for nursing education and practice are discussed. PMID- 6908960 TI - Sex-role identity and perception of professional self in graduates of three nursing programs. PMID- 6908962 TI - Moral reasoning and moral behavior among selected groups of practicing nurses. AB - This study examined the relationship between moral reasoning and moral behavior in 79 practicing nurses. Moral reasoning was measured by Rest's Defining Issues Test. Judgments about Nursing Decisions (JAND), developed by the investigator, was used to measure moral behavior. JAND is compromised of seven stories, each depicting a nurse in an ethical dilemma, with a total of 48 items. It measures two components of moral behavior: knowledge and valuation of ideal moral behavior and perception of realistic moral behavior. The hypothesis that moral reasoning would be positively related to knowledge and valuation of ideal moral behavior was tested by Pearson product moment correlation; the obtained coefficient of .28 was significant at the .01 level. The hypothesis that moral reasoning would be positively related to nurses' perception of realistic moral behavior was also tested by Pearson product moment correlation; the obtained coefficient of .19 was significant at the .05 level. Additional analyses showed significant differences in the knowledge and valuation component of JAND between educational groups, ethnic groups, age groups, and years of practice in nursing; but, there were no differences between these groups with respect to the perception of realist moral behavior component of JAND. Implications of the findings for nursing practice, education, and research are discussed. PMID- 6908963 TI - Open-closed mindedness, intolerance of ambiguity and nursing faculty attitudes toward culturally different patients. PMID- 6908964 TI - Employment patterns among newly hired hospital staff nurses; comparison of nursing graduates and experienced nurses. AB - Comparison of newly hired nursing graduates in their first hospital staff nurse positions and newly hired experienced nurses employed in the same hospitals revealed that the two groups were indistinguishable with respect to turnover patterns and rates, job hunting behavior, and job satisfaction levels. Type of basic nursing education did not alter results. Differences between the two groups were in the opposite direction from that expected based on the literature which emphasizes problems associated with role transition among new graduates. These findings imply that the process of job acclimation is fundamentally the same for the two groups. Implications for hospital and nursing administrators are discussed. PMID- 6908967 TI - Properdin factor Bf polymorphism and glyoxase I allotypes in Graves' disease. PMID- 6908965 TI - Radioimmunoassay of methionine(5)-enkephalin sulphoxide: phylogenetic and anatomical distribution. AB - A sensitive and specific radioimmunoassay (RIA) for the oxidised form of methionine(5)-enkephalin (Met(5)-Enk), Met(5)-Enk sulphoxide (Met(5)-Enk-S), has been developed. Antisera were raised in rabbits against Met(5)-Enk coupled to carrier proteins with glutaraldehyde or carbodiimide. Displacement of (125I) Met(5)-Enk bound to antiserum by Met(5)-Enk was poor, but Met(5)-Enk-S displayed good displacement suggesting that the Met(5)-Enk immunogen was oxidised to Met(5) Enk-S and that the antisera were formed against this compound. The sensitivity of the RIA for Met(5)-Enk-S was 0.02 pmole/tube using the most sensitive antiserum. The antisera showed negligible cross-reactivity with leucine(5)-enkephalin and with both native and oxidised endorphins. Cross-reactivity was between 15% and 28% with the fragment Met(5)-Enk (2--5) sulphoxide and between 9% and 25% with D Ala(2)-Met(5)-Enk sulphoxide. The antisera showed less than 0.01% cross reactivity with other Met(5)-Enk fragments and naturally occurring neuropeptides. Tissue extracts were oxidised with hydrogen peroxide prior to assay. Met(5)-Enk-S immunoreactivity (IMR) was detected in brain, pituitary gland, pancreas, and intestine extracts of the rat, chicken, toad and teleost, and in cerebral suboesophageal ganglion extracts of the snail. All tissue extracts showed parallelism in serial dilution to synthetic mammalian Met(5)-Enk-S, suggesting possible immunological identity. The results indicate that spontaneous oxidation of Met(5)-Enk immunogen occurs such that antisera are produced against the sulphoxide analogue of Met(5)-Enk, and may account for the relative insensitivity of some published RIAs using Met(5)-Enk standard. Our findings demonstrate a wide phylogenetic and anatomical distribution of Met(5)-Enk IMR. PMID- 6908968 TI - Looking for giardia. PMID- 6908969 TI - Still looking. PMID- 6908966 TI - Bf polymorphism and its relationship with HLA antigens in a sample of the Spanish Population: high BfF1 frequencies. AB - Bf allele frequencies were studied in a sample of the normal Spanish population and in family haplotypes. BfF1 shows a frequency higher than in other Caucasoid populations and closer to that found in Negroids. Basques show an even higher BfF1 frequency BfF1 is in strong linkage disequilibrium with B18. HLA-Bw44 is found to be the B12 split in linkage disequilibrium with BfF and Bw50-BfS1 association is confirmed. DR3--BfF1 are not in linkage disequilibrium in the normal Spanish population, in contrast to DR3--BfF1 in linkage found in a diabetic Spanish population. Results are discussed on the bases of the paleo North African Iberian population origins and of the use of Bf to define B12 and Bw21 splits. PMID- 6908970 TI - Renal function tests--2: water-deprivation response test, exogenous antidiuretic hormone response, and phenolsulfonphthalein-excretion test. PMID- 6908971 TI - Talking with pets: the search for a trustworthy friend. PMID- 6908974 TI - A clinical evaluation of the proximate stapling system for closing skin incisions. PMID- 6908973 TI - Maternal behavior in mares. PMID- 6908972 TI - Ventricular fibrillation during anesthesia. PMID- 6908975 TI - Animals and alcohol don't mix? PMID- 6908976 TI - A modified surgical approach to chronic otitis externa. PMID- 6908977 TI - Use of plaster casts to stabilize long-bone fractures in small animals (a photo essay). PMID- 6908978 TI - Thymoma and food-bolus choke in a dog. PMID- 6908980 TI - An acrylic maxillary splint used to correct malalignment of mandibular canine teeth in a dog. PMID- 6908981 TI - An unusual case of chronic hepatitis in a Kerry Blue terrier. PMID- 6908979 TI - Thoracic and abdominal wound in a cat shot with an arrow. PMID- 6908982 TI - The effect of aspirin on endogenous prostaglandin-F2a in dog plasma. PMID- 6908983 TI - Eperythrozoonosis as a cause of infertility in swine. PMID- 6908986 TI - Food-animal regional anesthesia: porcine blocks: lumbosacral (epidural). PMID- 6908985 TI - Cervopexy as a treatment for chronic vaginal prolapse in the cow. PMID- 6908987 TI - Local nasal anesthesia in the bull. PMID- 6908984 TI - Interdigital myxoma in a Hariana cow. PMID- 6908989 TI - Hip dysplasia in a timber wolf. PMID- 6908988 TI - A method for correcting vaginal prolapse in a cow. PMID- 6908990 TI - Use of acupuncture in treatment of laminitis in a horse. PMID- 6908992 TI - Anesthesia and supportive therapy during surgery for equine colic. PMID- 6908991 TI - Castration of mules by unskilled laymen: surgical correction of traumatic results. PMID- 6908993 TI - Mebendazole treatment of stomach-wall worm in the racing pigeon. PMID- 6908994 TI - Social and economic implications of cancer in the United States. PMID- 6908995 TI - [Mechanisms of action and clinical importance of C3-nephritic-factor (author's transl)]. AB - The C3-nephritic-factor is an autoantibody specific against C3-convertases. This IgG-immunoglobulin is particularly found in patients suffering from membranoproliferative glomerulonephritis and causes a complement-activation under elimination of physiological regulator mechanisms. The clinical importance of this factor is discussed. PMID- 6908996 TI - Effect of ultraviolet radiation and kinins on oxygen uptake by tissue slices and on basal metabolism in rabbits. AB - The experiments were carried out on 85 rabbits in 15 groups of 5-8 animals in each. The different groups received: 1) ultraviolet radiation once during 45 minutes or daily during 10 minutes for 6 weeks, 2) bradykinin intravenously 10 microgram/kg, 3) kallikrein 5 B.U./kg intramuscularly during 3 weeks. The levels of kinins and kininogen, and the activity of kallikrein and kininases were determined in the blood several times during 24 hours after radiation exposure, and at intervals of two weeks during long-term exposure to radiation. In the same time periods after exposure the basal metabolism and the uptake of oxygen by slices of the kidneys, liver, heart and skin in vitro were determined. Determinations of aerobic metabolism were carried out also after bradykinin injection and at weekly intervals during kallikrein administration. It was found that: 1) after exposure to ultraviolet radiation there was a high rise in the level of kinins and a fall of kininogen, the activity of kininogenases was raised and that of kininases was decreased, while oxygen uptake was reduced moderately; 2) exogenous bradykinin and endogenous kinins reduced oxygen uptake in vivo and in vitro. PMID- 6908997 TI - Vanadate-induced oliguria and vasoconstriction in the cat. AB - The effect of sodium orthovanadate (vanadate) on kidney function and hemodynamics was tested in chloralose anesthetized, fasting cats. Vanadate given i.v. caused a reversible, marked decrease in glomerular filtration rate and urine production without significantly affecting the fractional water excretion rate. In the recovery period, after administration of vanadate, urine flow and the urinary excretion rate of electrolytes were only slightly different from control values. This action of vanadate appears to be due mainly to constriction of the renal blood vessels leading to a fall in glomerular capillary pressure. Vanadate likewise caused a dose dependent decrease in arterial conductance and blood flow of other vessels in the splanchnic area, whereas the femoral and carotid arteries were reversely and less affected. The vascular effect appears to be caused by a direct action of vanadate on vascular smooth muscle, but the mechanism of action is still unsettled. PMID- 6908998 TI - Deficient activity of the alternative pathway of complement in beta thalassemia major. AB - Patients with thalassemia major suffer frequent and serious infections, especially after splenectomy. To explore the basis for this susceptibility, we examined activity of the complement system in sera from 24 patients. All sera had normal or increased activity of the classic complement pathway. However, six of the 24 (three with and three without splenectomy) had abnormal alternative pathway function, and mean alternative pathway activity was significantly decreased in both splenectomized and nonsplenectomized patients. Mean concentrations of C3, factor B, properdin, and immunoglobulins were normal. Defective alternative pathway function, especially in conjunction with asplenia, could contribute to the propensity to infection that exists in thalassemia. PMID- 6908999 TI - Methicillin-resistant Staphylococcus aureus bacteriuria. AB - Methicillin-resistant Staphylococcus aureus (MRSA) bacteriuria was detected in 11 of 41 patients colonized or infected with MRSA. The patients with bacteriuria generally were older than 40 years of age, five were diabetic, seven had prior indwelling uretheral catheters, two had undergone other urologic manipulations, and only one was clinically symptomatic. Eight patients received variable combinations of antibiotic therapy prior to the diagnosis of MRSA bacteriuria, and seven were still on antibiotic therapy at the time the bacteriuria was detected. Bacteriuria lasted four days to 14 weeks, and was eradicated promptly with cephalosporin therapy in five six patients. Bacteriuria in the untreated patients cleared spontaneously in one month. A single MRSA serotype (83A) predominated. The MRSA isolates were resistant in vitro to most antibiotics except vancomycin. Resistant colonies were observed within cephalothin disc zones of inhibition at 30C (resistance was confirmed by microtube-dilution sensitivity testing). MRSA disc sensitivity testing for cephalothin may be unreliable when performed at 35C. PMID- 6909000 TI - The demise of the traditional 5-40 workweek? PMID- 6909001 TI - Seven days on and seven days off. PMID- 6909002 TI - The aminoglycoside antibiotics. PMID- 6909003 TI - A severe case of viral myocarditis. PMID- 6909004 TI - The child undergoing a leg-lengthening procedure. PMID- 6909005 TI - Graduation/Termination. PMID- 6909006 TI - Opportunistic mycoses. PMID- 6909007 TI - Rhinocerebral Mucormycosis. PMID- 6909008 TI - Amphotericin B: Ten common questions. PMID- 6909009 TI - Whose autonomy is at stake? PMID- 6909010 TI - Human rabies. PMID- 6909011 TI - The Arab American in the health care system. PMID- 6909012 TI - Acute intermittent porphyria. PMID- 6909013 TI - Handling depression through activity. PMID- 6909014 TI - The manipulative patient. PMID- 6909015 TI - Nurses' feelings about working with the dying. PMID- 6909017 TI - The nurse training act: yesterday, today, and... PMID- 6909016 TI - Hyperbaric oxygen therapy. PMID- 6909019 TI - Verbal no-code orders. PMID- 6909018 TI - The "simple" analgesics. PMID- 6909020 TI - [Changes in the blood kallikrein-kinin activity in pregnancy and labor in women with late toxicosis]. PMID- 6909021 TI - The morphology of the amelanotic Greene melanoma. AB - Pieces of amelanotic Greene melanoma were transplanted onto the iris surface of rabbit eyes, where they started to grow rapidly after a dormant period of four to five days. Light microscopically, the melanoma cells appeared round or polygonal and contained large, lightly staining nuclei and prominent nucleoli. Electron microscopy revealed rather electron translucent nuclei containing only a small rim of heterochromatin immediately subjacent to the nuclear envelope. The very prominent, reticulated nucleoli frequently lay close to the nuclear surface. The cytoplasm of the cells showed a well developed Golgi field which contained myriad vesicles of different shape and density and cross-striated, membrane-bound organelles of early melanin synthesis. The mitochondria were short and the smooth surfaced endoplasmic reticulum was inconspicuous. The rough-surface endoplasmic reticulum was sparse and exhibited predominantly short segments. Like other very active cells, the melanoma cells contained a multitude of ribosomes. Melanoma cells which were not completely surrounded by other cells exhibited numerous processes at the free cell surface and, directly subjacent to these, a layer of very electron dense cytoplasm, indicating that these cells may possess a certain amount of motility. Many light and electron microscopical aspects of the amelanotic Greene melanoma are identical or similar to human uveal melanomas, especially of the epithelioid variety. On morphological grounds it is therefore possible to suspect a close biological relationship of these tumors. Thus, the use of the Greene amelanotic melanoma as a model for study of diagnostic and therapeutic problems in ophthalmology may be considered adequate. PMID- 6909022 TI - An evidence for adrenergic involvement in the choroidal circulation. AB - The ciliary nerve endings of adult albino rats were observed by transmission electron microscopy after the injection of 5,6-dihydroxytryptamine. The content of both large and small granular vesicles in these endings markedly increase in density by administration of the drug. The result suggests that the endings derive from the adrenergic nerve fiber. PMID- 6909023 TI - Programs SARGON and DELTA: two new principles for the automated analysis of the visual field. AB - The new Octopus programs SARGON and DELTA are described. The SARGON program makes possible the arbitrary distribution of a maximum number of 66 test locations with a resolution of up to 0.2 degrees across the 60 degrees visual field. Eighty user defined self-created programs can be permanently stored and recalled later at will from the program diskette.. The program DELTA evaluates perimetric examination results with the aid of a series of statistical tests and investigates whether the data base is sufficient to assume a significant deviation, or alternatively, whether a visual field defect can be explained simply by spontaneous fluctuations or if a true pathologic defect should be assumed at a particular level of significance. Furthermore, the program tests changes in the visual field as a function of time for their statistical significance. PMID- 6909024 TI - Physical forces involved in pseudophacodonesis and iridodonesis. AB - Studies of high-speed motion pictures of the eyes of patients after extracapsular (EC) and intracapsular (IC) cataract extraction show that pseudophacodonesis and iridodonesis are the result of oscillations of the fluids in the anterior segment of the eye. These oscillations, initiated by movement of the eye, result in shearing forces on the corneal endothelium which may result in damage. Similar motion of the vitreous causes shearing forces which may damage the retina. PMID- 6909025 TI - Dose-related interaction between timolol and adrenaline. AB - The effects on IOP of a combination of oral timolol maleate and adrenaline eye drops were investigated in a double-blind randomized trial using health volunteers. Timolol was given in two doses, 20 and 5 mg a day. One percent adrenaline eye drops were given to one eye, placebo to the other. The results showed a significant additive effect of adrenaline with the smaller dose of timolol, but with the larger dose of timolol the effect of adrenaline was antagonistic. These results may be due to an incomplete beta-blockade with the smaller dose of timolol, but a complete blockade with the larger dose. PMID- 6909026 TI - [Pigmented deposits into conjunctiva after local application of epinephrine (author's transl)]. AB - Prolonged local application of epinephrine produces deposits of pigment in the conjunctiva, which is found in conjunctival cysts or crypts. The fine granular structure sometimes shows concentric layers. Granular particles seen by electron microscope are often found adsorbed to the surface of microvilli. It is not known whether the electron-sense particles in the cysts or crypts have developed from active secretion or by influx from the conjunctival surface. The metabolic product of locally applied epinephrine is probably not a typical melanin (negative Masson-Hamperl staining), but appears to be a related pigment. PMID- 6909028 TI - Lysophosphatidic acid-induced aggregation of human and feline platelets: structure-activity relationship. PMID- 6909027 TI - [The influence of corticosteroids on the fibrinolytic activity indifferent tissues of the eye (author's transl)]. AB - The influence of corticosteroids on the fibrinolytic activity in different tissues of the eye was investigated. Rats were treated with corticosteroids, and the fibrinplate method of Todd 1962) was used to estimate the fibrinolytic activity. After 14 days treatment with corticosteroids the fibrinolytic activity decreased. In the control eyes no fibrinolytic activity was left after 6 h of autolysis. The eyes treated with corticosteroids, however, still had fibrinolytic activity. PMID- 6909029 TI - Arginase and kallikrein activities as biochemical indices of occupational exposure to lead. AB - In a group of 60 workers occupationally exposed to lead the blood and urine lead concentrations, haematocrit, ALA-D and arginase activities, and urinary 5 aminolaevulinic acid (ALA) and coproporphyrin concentrations, and kallikrein activity were determined. Correlation coefficients of -0.78 and 0.77 for Pb-B/ALA and Pb-B/arginase were found respectively for lead concentrations above 40 microgram/dl blood, and 0.83, 0.76, 0.74, and -0.64 for Pb-U/ALA, Pb-U/Cp-U, Pb U/kallikrein, and Pb.U/kallikrein, respectively. It seems that the increase in serum arginase activity may be indicative of liver damage while the decrease in kallikrein activity may indicate kidney damage in workers exposed to lead. PMID- 6909031 TI - Sexual harassment: no place for it in the workplace! PMID- 6909030 TI - Fetal rat lung phosphatidylcholine synthesis in diabetic and normal pregnancies: a comparison of prenatal dexamethasone treatments. AB - The effects of maternal diabetes upon fetal lung surfactant phospholipid metabolism were studied using 19-day gestational age fetal rats from mothers with streptozotocin-induced diabetes mellitus. In this experimental animal model, maternal glucose intolerance significantly impaired fetal body and lung development. However, incorporation of [14C]palmitate and [3H]choline into lung total and disaturated phosphatidylcholine was unimpaired in offspring of diabetic mothers. Dexamethasone, which is known to promote fetal lung maturation in normal pregnancies, was administered to diabetic and control mothers during late gestation. Prenatal dexamethasone inhibited lung growth in both diabetic and control pregnancies. While this agent slightly stimulated [14C]palmitate incorporation into total phosphatidylcholine and markedly enhanced [3H]choline incorporation into both disaturated and total phosphatidylcholine in control pregnancies, it failed to stimulate incorporation of either precursor into fetal lung from diabetic pregnancies. PMID- 6909032 TI - The court vs the disciplinary hearing. PMID- 6909034 TI - Special groups for special nurses. PMID- 6909033 TI - Nursing the mentally disordered offender. PMID- 6909035 TI - CNJ talks to Shirley Wheatley, independent nurse practitioner. PMID- 6909036 TI - Nursing diagnosis: a vital component of the nursing process. PMID- 6909037 TI - Patient compliance: is that what we really want? PMID- 6909038 TI - The costs of cancer: a challenge to health care providers. PMID- 6909039 TI - Mastectomy patients and the fear of cancer recurrence. PMID- 6909040 TI - Nurses as teachers and support persons for breast cancer patients. PMID- 6909041 TI - Meeting the information needs of patients on clinical trials: a new approach. PMID- 6909042 TI - Cancer nursing and the law. Emotional injuries. Part II. PMID- 6909043 TI - Programmed instruction: cancer care. Leukemia: the treatment of leukemia. PMID- 6909044 TI - Testing approaches to teaching breast self-examination. PMID- 6909045 TI - Estrogen receptors and advanced breast cancer. PMID- 6909046 TI - Mitral valve prolapse: its recognition and nursing implications. PMID- 6909047 TI - Writing for consumers. PMID- 6909048 TI - Collaborative practice: the joining of two professions. PMID- 6909049 TI - [Nursing process. 2. Nursing history taking]. PMID- 6909050 TI - [Constant tenderness and considerations to details - expectations about head nurses]. PMID- 6909051 TI - [Women's role and nursing - lessons from folk medicine. 1]. PMID- 6909052 TI - [The ideal forms of nursing and education (7). On graduate education. (3)]. PMID- 6909053 TI - [Modern nursing education]. PMID- 6909054 TI - Community outlook: hospitals at home. PMID- 6909055 TI - Pressure sores. Pinpointing the problem. Interview by Laura Swaffield. PMID- 6909056 TI - Pressure sores. Gauging the problem. Interview by Laura Swaffield. PMID- 6909057 TI - Slimming. Part 1. New ideas on behavior. PMID- 6909058 TI - Slimming. New ideas on eating. PMID- 6909060 TI - Slimming: wonderland or jungle? PMID- 6909059 TI - Home aids exhibition. PMID- 6909061 TI - Fat sheet. PMID- 6909062 TI - Childminding: minding matters. PMID- 6909063 TI - Childminding: Stephanie, Perena and me. PMID- 6909064 TI - The young child in the critical care unit. PMID- 6909065 TI - The organ donor. PMID- 6909066 TI - Nursing implication of toxic shock syndrome. PMID- 6909067 TI - Transsphenoidal hypophysectomy. PMID- 6909068 TI - Pancreatitis and the lung. PMID- 6909069 TI - Hypothyroidism. PMID- 6909071 TI - Behavior modification for adult onset diabetes. PMID- 6909072 TI - Self-monitoring of blood glucose. PMID- 6909070 TI - Hypersensitivity pneumonia. PMID- 6909073 TI - The need to improve diabetes education programs. PMID- 6909075 TI - Attitudes toward dietary management of diabetes among diabetic youngsters at camp. PMID- 6909074 TI - Diabetes education: report on financing and reimbursement. PMID- 6909076 TI - [Diet therapy of children suffering from obesity]. PMID- 6909077 TI - [Therapeutic nutrition in obesity]. PMID- 6909078 TI - [Pathogenetic treatment of acute pancreatitis]. PMID- 6909079 TI - [Cesarean section in modern obstetrics (II)]. PMID- 6909080 TI - [Trichomoniasis of the female genitalia]. PMID- 6909081 TI - [Systemic lupus erythematosus]. PMID- 6909083 TI - [Cholagogic agents]. PMID- 6909082 TI - [Hemostatic agents]. PMID- 6909084 TI - [Propaganda and the organization of a blood donor system without compensation]. PMID- 6909085 TI - [Health education work of an industrial enterprise health center]. PMID- 6909086 TI - [Bee venom treatment of lumbosacral radiculitis]. PMID- 6909087 TI - [Dispensary care of children with digestive organ diseases]. PMID- 6909088 TI - [Primary carcinoma of the Fallopian tube--a clinical study of 37 cases (author's transl)]. AB - Thirty-seven cases of primary fallopian tube carcinoma treated at our institution over the years 1946 to 1976 are described. The overall 5-years survival rate was 30%, although patients with early tumors had 42% survival rate. The single most important factor affecting survival appeared to be the extent of disease at the time of diagnosis. Present treatment modalities are discussed, even though the number of tube carcinomas are few, it might be useful to adopt an official classification. PMID- 6909090 TI - [Urodynamic findings in anamnestic urge incontinence (author's transl)]. AB - Cystometric finding of 93 urge incontinent and 157 not urge incontinent women were compared by evaluating the following 4 parameters: uninhibited detrusor contractions, first desire to void, maximum cystometric capacity and bladder compliance. Of these 4 parameters only uninhibited detrusor contractions were significant for the urodynamic diagnostic evaluation of urge incontinence. Bladder compliance especially showed no correlation to anamnestic urge incontinence. PMID- 6909089 TI - [The problem of so-called conservative treatment of the atypical cervical epithelium (author's transl)]. AB - There is an increasing tendency of a so-called conservative treatment of intraepithelial atypia. The new term of cervical intraepithelial neoplasia (CIN) supposedly called for a new concept of treatment. However, the term CIN replaces only the ambiguous terms of Carcinoma in situ and Dysplasia. The term CIN expresses the latter two being principally identical changes that are distinguishable only by differentiation. Persistent dysplasia is nothing but a highly differentiated Carcinoma in situ and must be treated as such. - For final diagnosis of CIN not only the histological pattern must be known but above all the relationship to the stroma and the extent of changes. NEither cytology nor colposcopy and directed biopsy or a combination of these can define the lesions with such accuracy as is necessary as a basis for a really adequate treatment. It could be proved that treatment results of Carcinoma in situ depended on the quality of primary diagnosis. Out of 390 cases that were treated after limited biopsy, eight died of cancer. After treatment of 1012 cases with conization alone there was not one fatal case. The danger of so-called conservative treatment lies not only in unrecognized invasive lesions but above all in preinvasive lesions remaining in deeply situated glands. Their discovery may fail in spite of regular follow-ups. They will reappear possibly only after a long latency period as invasive cancer. PMID- 6909091 TI - [Comparative determination of the vesico-urethral angle in incontinence via ultrasound and lateral urethro-cystogram (author's transl)]. AB - Pre-operative diagnostic procedures in evaluating stress urinary incontinence in women became increasingly important within the last years. In many clinics the measurement of the posterior vesico-urethral angle using lateral urethro cystograms has become an eminent criterion for the selection of the operative method applied. Until now, this angle could be measured by employing X-ray examination techniques. In this paper, an ultrasonic examination with the same accuracy as in X-ray. The technique of both methods and their advantages and disadvantages are discussed. PMID- 6909092 TI - [Endometritis--a diagnostic problem. Differentialdiagnostical considerations including histological and microbiological methods (author's transl)]. AB - In 100 patients with the assumed diagnosis "endometritis" an examination program including histological and microbiological methods was conducted. In only 73% of these, the histological examination confirmed the assumed diagnosis, and only in 3% concerning the microbiological tests; therefore other diagnoses such as peritoneal irritation at ovulation, adenomyosis uteri and spastic pelviopathias were dominant. The diagnosis of an endometritis therefore is often an exclusive one and should induce subtle examination methods before an unspecific antibiotic therapy is begun. This procedure is absolutely possible regarding out-patients. PMID- 6909093 TI - [Immature solid teratoma of the uterine cervix (author's transl)]. AB - A 27-year-old woman with an inconspicuous anamnesis developed within two years a solid tumor of about 10/5 cm in size, and extending from the left corner of the external os up to the lumen of the vagina and consisting of partly immature ectodermic, mesodermic and endodermic parts. After the radical removal of the tumor by means of abdominal hysterectomy and left-sided adnexectomy no signs of a recurrence could be observed for about ten years. Except a shortly described case of teratoma of the endometrium no further case of a uterine teratoma has been mentioned in the literature so far. A brief discussion of differential diagnosis and etiology is also present. PMID- 6909094 TI - [A lymphogranulomatosis simulating an ovarian tumour (author's transl)]. AB - A case of lymphogranulomatosis involving the left broad ligament in a 68-year-old patient is reported. The lymphogranuloma with the extent of two fists presented like an immobile ovarian tumour on palpation. An abdominal hysterectomy with bilateral salpingo-oophorectomy and lymphnode resection was performed. No complications occurred during the postoperative course. Haematologic treatment was subsequently initiated. PMID- 6909095 TI - [Sonographic demonstration of the fetal extremities in the mid-trimester (author's transl)]. AB - In 251 pregnancies fetal extremities were systematically examined by means of an ultrasound sector scanner between the 12th and 28th week of gestation. The procedure is demonstrated by typical pictures. The long tubular bones, hands and feet were visualized regularly, and differentiation of radius and ulna or tibia and fibular was possible. Studies took between 5 and 25 minutes. In all cases the length of the diaphyses was determined, resulting normal growth tables and rate of growth curves. Between the 12th and 28th week, the humerus grows from 9 to 51 mm., the radius from 7 to 46 mm., the femur from 10 to 55 mm., and the tibia from 8 to 48 mm. Sonographic depiction of fingers and clavicles was also quite successful. For best results, examinations were done between the 16th and 20th week. In three fetuses later aborted, sonographic and direct (after preparation) measurements of bone length for the diaphysis differed by no more than 4%. The study shows that visualization of the extremities regularly succeeds in the mid trimester. A multitude of localized or systemic limb malformations may be recognized. In cases with known predisposition to malformations a regular ultrasonic checkup should be performed, thus extending the scope of prenatal diagnosis. PMID- 6909096 TI - [Ultrasonographic findings in "Potter's syndrome" (author's transl)]. AB - The foetal Potter's syndrome represents a relatively frequent malformation syndrome, the incidence being 0.3% of all live births. The phenotypical changes seen in these newborn occur in complete bilateral renal agenesia = the original Potter's syndrome, but they are also found in various congenital cystic diseases of the kidneys and/or the other urinary organs. In additional to the original Potter's syndrome, a patho-anatomical classification of cystic deformations of the kidneys or of the efferent urinary organs was introduced by Osathanondh and Potter (1976) (Potter Type I-Type IV). These severe foetal malformations can be diagnosed at least in part via timely ultrasonic examination during the first half of the pregnancy period. In such cases, an oligoamnion or sometimes an anhydramnion is regularly observed as principal sign. This diagnosis is probably confirmed if the foetal urinary bladder is not demonstrable following application of furosemide (Campbell). Occasionally the cystic changes of the urinary organs can be proven direct by means of sonography. Ten examples of cases are described presenting the typical ultrasonographic findings in the so-called extended "Potter's syndrome" (oligoamnion or anhydramnion, malformations of the kidneys and/or the efferent urinary organs and phenotypical changes). Due to their infaust prognosis these foetal diseases result in the indication for termination of pregnancy. PMID- 6909097 TI - [Preventive hysterectomy versus paragraphs 224 and 225 of the german penal code (author's transl)]. PMID- 6909098 TI - Carolyne Davis, R.N., administrator, Health Care Financing Administration. PMID- 6909099 TI - Reality orientation in a general hospital. PMID- 6909101 TI - When it's time to face dying. PMID- 6909100 TI - Ethical considerations in gerontological nursing research. PMID- 6909103 TI - Some very good years. PMID- 6909102 TI - Reflections: the aged today and tomorrow. PMID- 6909104 TI - John, a severely regressed man. PMID- 6909107 TI - Nutrition: eating habits--chance or choice? PMID- 6909105 TI - Common concern: accidents and older adults. PMID- 6909106 TI - Drugs and the elderly: when the patient is taking a sulfonylurea. PMID- 6909108 TI - 70+ and going strong: what one octogenarian does with her time. PMID- 6909109 TI - Immunolocalization of kallikrein in porcine pancreas at the ultrastructural level. AB - The immunological localization of kallikrein in porcine pancreatic tissue was investigated by an immunoferritin method and presented by electronmicroscopy. Kallikrein was found in the zymogen granules of the pancreatic acinar cells as well as in the golgian area of the same cells. On the same section, all the zymogen granules of all acinar cells gave a positive reaction. Kallikrein was not found in the centroacinar or interstitial cells. PMID- 6909110 TI - Of women and walls. PMID- 6909111 TI - Transcultural nursing research--alien in an alien land. PMID- 6909112 TI - Beyond umbrellas: health care delivery in Kenya. PMID- 6909113 TI - Variation in stress and coping in three migrant settlements - Guatemala City. PMID- 6909115 TI - Folk health practices among north coastal Peruvians: implications for nursing. PMID- 6909114 TI - Solving problems of cross-cultural health teaching: the Filipino childbearing family. PMID- 6909116 TI - Evolution of nursing sciences: implications for nursing world wide. PMID- 6909117 TI - [The obese diabetic]. PMID- 6909118 TI - [Spasmophilia and tetany]. PMID- 6909119 TI - [Fecalogram]. PMID- 6909120 TI - [Alcohol, biology and child health. II. Metabolism of alcohol in the young]. PMID- 6909121 TI - [Diagnosis of phospho-calcium metabolism disorders]. PMID- 6909122 TI - [Puerperal psychoses]. PMID- 6909124 TI - [Birthweight]. PMID- 6909123 TI - [Psychoanalysis: myths and reality]. PMID- 6909125 TI - [Tetanus]. PMID- 6909126 TI - [Ca/P metabolic disorders]. PMID- 6909127 TI - [Fecalogram]. PMID- 6909128 TI - [Alcohol, biology, and child health. III. Biological basis of alcohol dependence]. PMID- 6909130 TI - [Temperature chart and rounds]. PMID- 6909129 TI - [Psoriasis]. PMID- 6909131 TI - [How to help solve problems]. PMID- 6909133 TI - [Teaching of hospitalized children]. PMID- 6909132 TI - [Private practice]. PMID- 6909134 TI - [At James Bay: nurses in satellite camps]. PMID- 6909135 TI - [Maternal self-help groups during the postnatal period]. PMID- 6909136 TI - [Abused women]. PMID- 6909137 TI - [Promoting the development of young children]. PMID- 6909138 TI - [Health education, life education. Point-blank]. PMID- 6909139 TI - [Self-actualization: myth or reality?]. PMID- 6909140 TI - [University and the nurse]. PMID- 6909141 TI - [Bladder reeducation and self-catheterization in urinary incontinence]. PMID- 6909142 TI - [The adolescent and his breakfast: what is the situation?]. PMID- 6909143 TI - Council targets broad services. PMID- 6909144 TI - How is the NCSBN financed? PMID- 6909145 TI - Exploring funding options. PMID- 6909147 TI - Loneliness: the syndrome. PMID- 6909146 TI - Uses of CPI. PMID- 6909148 TI - Sexual attitudes in a group of older women. PMID- 6909149 TI - Geriatric abuse. PMID- 6909150 TI - Nurses' perceptions of the meaning of support in nursing. PMID- 6909151 TI - Common characteristics of abused women. PMID- 6909152 TI - Goal attainment of psychiatric clients after group experience to learn social independence skills. PMID- 6909153 TI - Self-consistency as a dimension of self-concept related to birth order in families of five to seven siblings. PMID- 6909154 TI - Death education for the elderly. PMID- 6909155 TI - Relationships between attitudes toward family change of residence and children's postmove adjustment. PMID- 6909156 TI - Play therapy: a review of theories and comparison of some techniques. PMID- 6909157 TI - Someone is lonely. PMID- 6909158 TI - The consultation process. PMID- 6909159 TI - Identification of environmental stressors for patients in a surgical intensive care unit. PMID- 6909160 TI - Behind the veil: the mental health of Asian women in Britain. 1. Life in Asia. PMID- 6909161 TI - Health problems of London's Asian and Afro-Caribbeans. PMID- 6909162 TI - Making a nurse into a health visitor. PMID- 6909163 TI - Feminism and health visiting. PMID- 6909164 TI - What health visitors say they do - a job description approach. PMID- 6909165 TI - Focus on school health. What school nurses want: results of the school nurses' questionnaire. PMID- 6909166 TI - Present day practice in infant feeding: 1980. New revised version of 1974 Oppe Report. PMID- 6909167 TI - Behind the veil: the mental health of Asian women in Britain. 2. Migration and life in Britain. PMID- 6909168 TI - The primary health care team. PMID- 6909169 TI - How health visitors' aims evolve in a group practice. PMID- 6909170 TI - We need the primary health care team. PMID- 6909172 TI - Child abuse: appearing in court. A practical course on court procedure. PMID- 6909171 TI - The health visitor and the law: confidentiality of case records. PMID- 6909173 TI - Know your organizations: Association for Research into Restricted Growth. PMID- 6909174 TI - The menopause: how much do women know? PMID- 6909175 TI - The health visitor and speech impaired children. PMID- 6909177 TI - Know your organizations: Parkinson's Disease Society. PMID- 6909176 TI - The 'Outside World' Society. PMID- 6909178 TI - Allergy to cows' mild protein. PMID- 6909179 TI - Cows' milk allergy in babies -- a review. PMID- 6909180 TI - Maternal food allergy as a cause of infantile colic in the breast fed baby. PMID- 6909181 TI - The importance of support for the breast feeding mother at home. PMID- 6909182 TI - Breast feeding guidelines for a health district. PMID- 6909183 TI - A breast feeding circle. PMID- 6909185 TI - National Association for Maternal and Child Welfare. PMID- 6909184 TI - Behind the veil: the mental health of Asian women in Britain. 3. Preventing stress--the role of the health visitor. PMID- 6909186 TI - The 1979 Nurses, Midwives and Health Visitors Act. PMID- 6909188 TI - Supraventricular tachycardias. PMID- 6909187 TI - Atrioventricular dissociation. PMID- 6909189 TI - Detection, prevalence, and significance of arrhythmias during exercise. PMID- 6909190 TI - Effects of alternative techniques of low-dose heparin administration on hematoma formation. AB - A small clinical trial was conducted to compare a modified subcutaneous injection technique with the standard subcutaneous method. The data in this study do not strongly support the use of either technique. However, the modified subcutaneous method may be preferable in that fewer injection-site hematomas formed. Further research with a larger population is indicated before either method can be recommended over the other. PMID- 6909192 TI - Oxygen consumption and hemodynamic and electrocardiographic responses to bathing in recent post-myocardial infarction patients. PMID- 6909191 TI - Effect of backrest position on cardiac output measured by the thermodilution method in acutely ill patients. PMID- 6909193 TI - A new, versatile blood gas syringe. PMID- 6909194 TI - Reading pulmonary artery and pulmonary capillary wedge pressure waveforms with respiratory variations. AB - Various techniques for reading pulmonary artery and pulmonary capillary wedge pressures have been described. We feel that the most easily obtained and accurate method for reading pressures with respiratory variations should be with reference to end expiration. This is a relatively constant period of intrathoracic pressure and allows for a stable pressure waveform, which can be measured easily. No matter which technique is utilized, a standard procedure should be adopted by those reading the pressures and understood by those who must interpret them. Consistency in the method of pressure waveform reading is important to ensure meaningful measurements and subsequent appropriate treatment of the patient. PMID- 6909195 TI - Nasal oxygen sampler. PMID- 6909196 TI - Measuring tracheal tube cuff pressures--tool and technique. AB - A three-part study identified factors essential to accurate determination of pressure exerted against the lateral wall of the trachea by three types of endotracheal tube cuffs. Part I compared 31 mercury sphygmomanometer measurements of tracheal cuff pressures to those of pressure-sensitive aneroid Portex manometer during simulated intubation and found 99.28% of mercury manometer readings accurate to within 2 mm Hg of Portex readings. Part II demonstrated that cuff compliance (i.e., the distensibility of the cuff material) influences such pressure determinations. Part III compared two methods of obtaining tracheal cuff pressure readings with the mercury sphygmomanometer during simulated intubation. Accurate measurement was made only with a stopcock system that simultaneously opened to the cuff, the manometer, and the inflator syringe and when a separate cuff distensibility factor was used in the computation. PMID- 6909197 TI - Premature ventricular contractions: Which ones require treatment? AB - Treatment of ventricular arrhythmias remains a difficult problem owing to our lack of understanding of etiology, prognosis, and efficacy of various antiarrhythmic agents. Lidocaine appears to prevent ventricular fibrillation during the CCU of myocardial infarction. Warning arrhythmias seen in the CCU do not in actuality accurately warn the clinician of risk of fibrillation. Secondary prevention of sudden death following infarction with antiarrhythmic agents may be of some value. There is little to suggest that drugs available in the United States are efficacious for this use. For the most part, treatment of outpatients with ventricular arrhythmias probably should be confined to those patients with symptomatic arrhythmias or to patients with complex ventricular arrhythmias and other objective evidence of cardiac disease. PMID- 6909198 TI - The effects of drugs on the electrocardiogram--a reference chart. PMID- 6909199 TI - Multiple sclerosis--new ideas and a new test. PMID- 6909200 TI - Acute myocardial infarction and fascicular block. AB - Left anterior fascicular block may mask an IWMI. On the other hand, a narrow QS deflection in a VF is often misinterpreted as evidence of extensive inferior wall infarction. Vectorcardiographic analysis usually establishes the coexistence of LAFB and IWMI. Standard Lead II of the ECG is the most valuable in differentiating the etiology of ALAD: (1) rS pattern in LAFB, (2) Qr or QR in IWMI, or (3) a QS pattern or a smaller or slurred r wave with a deep S wave in combined IWMI and LAFB. PMID- 6909201 TI - Postdischarge follow-up. PMID- 6909202 TI - Legal aspects of communication with and about the pediatric patient. PMID- 6909203 TI - Sickle-cell anemia. PMID- 6909204 TI - Folic acid deficiency related to the use of goat milk for infant feeding. PMID- 6909205 TI - The costs of children: are they worth it? PMID- 6909206 TI - Case recognition and assessment of father-daughter incest. PMID- 6909207 TI - Preschool feeding problems: it's not nutritious unless they eat it. PMID- 6909208 TI - Notes on continuing education. Libraries: a resource for continuing education. PMID- 6909210 TI - Integration of the role of clinical nurse specialist. PMID- 6909209 TI - Continuing education in nursing dissertation abstract. PMID- 6909211 TI - Workshop worries: planning is the answer. PMID- 6909212 TI - Is the computer the answer? PMID- 6909213 TI - Teaching mental health principles through continuing education. PMID- 6909214 TI - Notes on continuing education. Employee mental health: a self-directed learning approach. PMID- 6909215 TI - Continuing education: how do you build a program? PMID- 6909216 TI - The new graduate socialization. PMID- 6909217 TI - Evaluation of Maine's Telelecture continuing education program: part II. PMID- 6909218 TI - A workshop for development of simulation games in nursing. PMID- 6909219 TI - Methods of teaching--revisited displays and exhibits. PMID- 6909220 TI - Teaching staff to cope with patient violence. PMID- 6909221 TI - The nursing process: application of current thinking in clinical problem solving. PMID- 6909222 TI - Course evaluation in post-basic education. AB - Course evaluation is defined 'as the collection and use of information in order to make decisions about an educational programme' (Cronbach 1963). The study described in this paper was undertaken by members of the professional and research staff of the Joint Board of Clinical Nursing Studies, London. The paper describes how the need for work on course evaluation arose and how a package was developed and piloted in 15 course centres with a total of 205 students. The ways in which the package is being used by schools of nursing and colleges of higher and further education is also described. The philosophy that evaluation has an important part to play in developing dynamic and sound educational systems is emphasized. Evaluation should be an integral part of every course and planned at the outset with other parts of the detailed course programme, involving both students and teachers in measuring the effectiveness of the course. PMID- 6909223 TI - Indicators for nursing practice: the use of research findings. AB - Until recently discussion about nursing research centred on the need to get it carried out. Attention is now being focused on how to get nursing research used, since so far, such research findings has not, on the whole, been assimilated into practice. Until this occurs the practice of nursing will not and cannot be research-based in any meaningful way. It is postulated that nursing research findings provide nurses with indicators for practice. This assumes that such findings are available and that the main barrier to their use is the poor communication of this research, (in a form they can understand) to nurse practitioners. However recent research into the use of research findings casts doubt on this assumption and it can be argued that such a view is too simplistic. In this paper therefore, three questions are asked: (1) Are relevant nursing research findings available which provide indicators for practice? (2) What indicators do such findings provide? (3) Are such findings used by nurse practitioners? Using specific examples from nursing research, ideas and suggestions are put forward which provide a basis for possible answers. Finally the paper discusses the interdependence of research and practice and the need for them to develop together. PMID- 6909224 TI - Changes in alcohol consumption after childbirth. AB - The early post-partum period is one of the few times of life stress for which health care professionals recommend alcohol consumption. In this study, a group of nursing mothers who had delivered normal full-term, first-born infants were examined during the 1-month period following childbirth. Data were collected on alcohol consumption patterns prior to and during pregnancy and following childbirth. Most women reported abstaining or decreasing consumption during pregnancy. Those who continued to drink during pregnancy reported drinking on social occasions, rather than when depressed or bored. During the post-partum period, a number of women began drinking. By far the most common post-partum drinking situation was during or prior to breast feeding. Reportedly, many women were advised to drink by nurses and doctors in order to relax and to aid the letdown reflex. Several factors seem worth noting. First, professional advice may be based on misinformation. Animal studies have suggested that alcohol inhibits the letdown reflex and may interfere with nursing. Secondly, because alcohol has been shown to enter the milkstream, attention should be given to possible harmful effects of alcohol (on the newborn) during nursing. Nurses could easily incorporate up-to-date information into their nursing practice. PMID- 6909225 TI - Attitudes of psychiatric hospital staff towards mental illness. AB - The use of the social model of psychiatry as a form of treatment is increasingly accepted as a legitimate therapy. This is expressed in the continued growth of the 'therapeutic community' regimes. However, investigations into components of the social model, i.e. attitudes of nursing staff in psychiatric hospitals, have not accompanied this growth. A cross-section of research over the past 25 years has shown an omission of behavioural correlations in attempting to measure staff attitudes. Research into attitudes expressed indicate a correlation between age, education, regime in hospital and occupation and the responses to attitude questionnaires. Without behavioral correlations however, the value of this research is very questionable. A few studies have included behavioral correlations such as perception of staff, discharge rates and length of stay in the community. An example of an area in nursing that attitude studies with behavioral correlations could usefully be employed is in examining the effectiveness of using staff from different cultures in therapeutic communities. PMID- 6909226 TI - Polygamy: a cultural trait and maternal and child health. AB - This study indicates that it is probable that the cultural trait of polygamy was instituted as an adaptive measure in a particular ecology within a particular tribal group. Polygamy perpetuated because of its positive contribution to maternal and child health. The study further indicates that it is also probable that monogamy as a foreign cultural trait and its introduction without concomitant changes in other spheres of the ecosystem (biophysical and social environment) must have produced a negative effort on maternal and child health. The particular ecosystem is described and its effects on maternal and child health are pointed out. PMID- 6909227 TI - The contribution of research to the understanding of nursing. AB - In summary, it is contended that the research being carried out by nurses in a university is rich source for analysis and synthesis, and that the synthesis itself will produce a new and unique contribution to the understanding of nursing. The methodology of theoretical research may well take in a taxonomy of cognitive skills which follows Bloom's (1956) taxonomy of educational objectives. The propositions, hypotheses and generalizations evolved would demand evaluation in terms of internal evidence and external criteria. But one would expect to find as a result of analysis and synthesis the emergence of new concepts and theories not clearly identified before. PMID- 6909229 TI - The pros and cons of having a nurse education research unit in a university. PMID- 6909228 TI - The pros and cons of having a nursing research unit in a university. PMID- 6909230 TI - The problems of safeguarding the community's interest if students are doing research. PMID- 6909231 TI - Nursing research and higher education. PMID- 6909232 TI - A team approach to patient death and staff grieving. PMID- 6909233 TI - The psychological adjustment of a CAPD patient. PMID- 6909234 TI - Hemodialysis and the spinal cord injury patient. PMID- 6909235 TI - Kinetic modeling: a nursing perspective. PMID- 6909236 TI - Dialysis staff: their feelings and how they cope. PMID- 6909237 TI - Home-training peritoneal dialysis in pediatric patients. PMID- 6909238 TI - Certification for hemodialysis technicians: present limitations and future potential. PMID- 6909239 TI - Continuous ambulatory peritoneal dialysis in pediatrics. PMID- 6909240 TI - Research and the nephrology nurse. PMID- 6909241 TI - Teaching students on dialysis. PMID- 6909243 TI - Continuous ambulatory peritoneal dialysis nursing follow-up: how much times does it take? PMID- 6909242 TI - Assessment of the role of the community renal nurse. PMID- 6909244 TI - Experience with continuous ambulatory peritoneal dialysis. PMID- 6909245 TI - The use of the Amicon filter in dialysis related complications. PMID- 6909246 TI - Improving communication between families and dialysis staff: a parent's point of view. PMID- 6909247 TI - Managing stress in a hemodialysis unit. PMID- 6909248 TI - The use of bicarbonate-buffered dialyzing solution for chronic hemodialysis patients with established acetate buffer intolerance. PMID- 6909249 TI - A cooking nutrition program for a pediatric hemodialysis unit. PMID- 6909250 TI - The cost of quality health care. PMID- 6909251 TI - To treat or to allow to die: an ethical dilemma in gerontological nursing. PMID- 6909252 TI - A humanistic view of the nurse and the dying patient. PMID- 6909253 TI - Knowledge levels of personnel in gerontological nursing. PMID- 6909254 TI - Identification of health problems at well elderly clinics. PMID- 6909256 TI - AAFP Position Paper on aging. PMID- 6909255 TI - Fostering positive attitudes toward the elderly: a teaching strategy for attitude change. PMID- 6909257 TI - Screening of older adults--an ethical issue. PMID- 6909258 TI - Gerontological nursing research revisited. PMID- 6909259 TI - Reality orientation and effective reinforcement. PMID- 6909260 TI - Interdisciplinary collaboration between nursing and dental hygiene: clinical care for the elderly. PMID- 6909261 TI - Physiologic aspects of confusion. PMID- 6909262 TI - Use of health assessment for placing patients for geropsychiatry. PMID- 6909263 TI - Decision making for nursing home admission: a preliminary study. PMID- 6909264 TI - So very vulnerable. PMID- 6909265 TI - Social organization and nurses' attitudes toward older persons. PMID- 6909267 TI - Aged abuse. PMID- 6909266 TI - Perception of health by the elderly. PMID- 6909268 TI - Developing a course in gerontologic nursing. PMID- 6909269 TI - Fear of loss and attachment: a major dynamic in the social isolation of the institutionalized aged. PMID- 6909270 TI - Retirement: aspects, response, and nursing implications. PMID- 6909271 TI - Simple methods for preparing EAC1,4b,2a,3b and EAC4b,3b with human or guinea pig complement components using an anticomplementary agent, K-76 monocarboxylic acid. PMID- 6909272 TI - High frequency of the properdin factor Bf F1 and its linkage to HLA in French Basques. AB - We studied 201 unrelated French Basque individuals for HLA and Bf polymorphisms. The haplotypes of eighty-seven of them were deduced from family studies. The results show the frequency of the Bf F1 allele (0.1393) which is the highest one currently reported. They confirm the high frequencies of HLA-Aw19.2 and B18 previously reported in that population and show that a whole haplotype with strong linkage disequilibria, namely Aw19.2, Cw5, B18, Bf F1, DRw3 is frequent. On the other hand, the gene frequency of Bf S is decreased (0.5497) as compared with the other European Caucasoid populations, while a slight increase in the Bf F gene frequency (0.2960) appears. These results point out that it is of importance to consider the genetic background choosing the population where linkage disequilibria are to be studied. PMID- 6909274 TI - [Two female patients' reactions to pituitary gland tumor (author's transl)]. PMID- 6909273 TI - [The dynamics and its clinical significance of complement system, especially alternative pathway related to normal human pregnancy, delivery, puerperium and fetus (author's transl)]. AB - The author studied human complement system, especially alternative pathway as a primitive biological defense system, in maternal serum during normal pregnancy, delivery and puerperium. The results obtained were as follows. 1. The mean value of hemolytic activity of alternative pathway (AlCH50) in healthy women was 18.3 +/- 1.1. This value was increased gradually in progress of gestational stages up to 26.6 +/- 2.3 of the average in the last trimester. Stochastically, significant differences about this value was noted between in the first trimester and in the last. This AlCH50 is decreased temporarily at delivery, and it was increased again rapidly, then went down to normal range about one month after delivery. 2. The average of immunochemical C3PA by SRID method during pregnancy was 22.5 +/- 0.4 mg/dl. It was significantly higher than the average 18.1 +/- 0.4 mg/dl of 59 healthy women. C3PA was noted to remain high level constantly during pregnancy. This C3PA level after delivery was observed to take a similar pattern as AlCH50. 3. beta 1C/1A globulin (C3) in 19 healthy women was 60.7 +/- 2.1 mg/dl. This C3 was also increased gradually during pregnancy up to maximum level of 87.5 +/- 2.8 mg/dl at the 3rd trimester. 4. Classical pathway (CH50, C4 and Cl INA) and fetal complement level were investigated at the same time and discussed here. PMID- 6909275 TI - [Nursing care of the patient with Addison's disease (author's transl)]. PMID- 6909276 TI - [Nursing of gout patient (author's transl)]. PMID- 6909277 TI - [The impact of premenstrual endocrine changes on women (author's transl)]. PMID- 6909279 TI - [Nursing care of diabetes in pregnancy (author's transl)]. PMID- 6909278 TI - [How to control diabetes mellitus? (author's transl)]. PMID- 6909280 TI - [Diabetic neuropathies and nursing care (author's transl)]. PMID- 6909281 TI - [Care of diabetic foot problems (author's transl)]. PMID- 6909282 TI - [Survey of the nursing activities in a psychiatric ward (author's transl)]. PMID- 6909284 TI - [A study on health examination behavior of the elderly (author's transl)]. PMID- 6909285 TI - [Ahead to an aggressive life with age (author's transl)]. PMID- 6909283 TI - [Thyrotoxic crisis and nursing care (author's transl)]. PMID- 6909286 TI - Managers and leaders: are they different? PMID- 6909287 TI - General systems theory: applications for organization and management. PMID- 6909288 TI - Clarity of expression in interpersonal communication. PMID- 6909289 TI - Penicillins - Part I. PMID- 6909290 TI - Decubitus ulcers: new treatments for an old problem. PMID- 6909291 TI - Hiccups: a passing annoyance or a true problem? PMID- 6909292 TI - Getting a job in nursing: how to make your choice a good one. PMID- 6909293 TI - A nurse's guide to continuing education. PMID- 6909294 TI - What's so special about my specialty: Coronary care nursing. PMID- 6909295 TI - The great imitator: understanding lupus erythematosus. PMID- 6909296 TI - Babies having babies: the epidemic of teenage pregnancies. PMID- 6909297 TI - Learning by doing. PMID- 6909298 TI - When your patient is a nurse. PMID- 6909299 TI - The problem patient: the dying of the light. Nursing strategies for the patient who is going blind. PMID- 6909301 TI - Penicillins - Part II. PMID- 6909300 TI - What's so special about my specialty? Psychiatric med nursing. PMID- 6909302 TI - A generalized model for the interaction of microwave radiation with bound water in biological material. AB - Calculations have been performed concerning the deposition of microwave energy in bound water surrounding a biological macromolecule immersed in a continuum consisting of free water and dissolved ions. In particular a previous model of a hydrated macromolecule has been generalised to one where the relaxation frequency of the bound water varies across the layer, and the calculations have been carried out for three combinations of values of ionic conductivity of the bound water and the continuum. When these conductivities are equal, but low, the average energy deposition per unit volume in the bound water is greater, sometimes by at least an order of magnitude, than that in the continuum at frequencies in the region of hundreds of MHz to a few GHz. As the ionic conductivity increases this effect decreases and at conductivities equal to that of physiological saline the specific energy deposition in the bound water is not more than around twice that in the surrounding electrolyte continuum over this frequency range. Therefore, for tissues of high bound water content exposed to microwaves of a given power density the biological effect produced is enhanced. For a biological tissue of high ionic conductivity with 20% of its water in the bound state the overall energy absorption would be 25% greater at certain frequencies than if all the water were in the free state. For materials of low ionic conductivity the increase would be more than one order of magnitude. PMID- 6909303 TI - The effect of microwaves on dimensions and nucleic-acid concentration in snail neurons. AB - Effects of microwaves (continuous wave, frequency 2450 MHz, rate of energy absorption 15.5 mW/g, irradiation time 60 min) on isolated subesophageal ganglia of Helix lucorum snail were studied. During exposure a constant temperature of the solution in which the ganglia were bathed was maintained. It was found that such an exposure led to a decrease in the concentration of nucleic acids in snail neurons as well as to an increase of nuclear area and to dimunition of cytoplasmic area. PMID- 6909304 TI - Complement receptor positive spleen cells in microwave (2450-MHz)-irradiated mice. AB - Male CBA/J mice were exposed under far-field conditions in a temperature and humidity controlled environment to 2450-MHz (CW) microwaves. Mice were exposed once for 30 minutes at a power density of 15, 20, 30, or 40 mW/cm2. The whole body-averaged dose rate was approximately 0.7 mW/g per mW/cm2. Six days after irradiation, the percentage of complement-receptor-positive (CR+) spleen cells was determined. No difference was observed in the percentage of CR+ spleen cells of young adult (10-12-week-old) mice exposed at any of the power densities as compared with sham-irradiated controls. However, a significant (P less than .05) increase was observed in the percentage of CR+ cells from 16-week old mice exposed at 40 mW/cm2. This increase in CR+ cells was accompanied by a significant (P less than .05) decrease in the number of nucleated cells in the spleens of these mice. This change in CR+ and nucleated spleen cells was not consistently produced. The available data indicate that the age and strain of the mouse, the microwave exposure characteristics, and the environmental conditions may all be sources of variation that affect the CR+ end point. PMID- 6909305 TI - Observations of rat fetuses after irradiation with 2450-MHz (CW) microwaves. AB - Female Sprague-Dawley (CD) rats were exposed to 2450-MHz (CW) microwave radiation at incident power densities of 0 or 28 mW/cm2 for 100 min daily on the 6th through 15th day of gestation. The whole-body specific absorption rate at 28 mW/cm2 is estimated to be 4.2 W/kg. These exposure conditions raised rats' average colonic temperatures to 40.3 degrees C at the end of irradiation. There were 67 sham-irradiated and 70 microwave-irradiated females. When these groups were compared, no significant differences were found in pregnancy rates; in the numbers of live, dead, or total fetuses; in the incidences of external, visceral, or skeletal anomalies or variations; or in the body weight of live fetuses. It is concluded that these conditions do not have an effect on the gross structure of the fetal rat when applied repetitively during post-implantation pregnancy. It is also strongly suspected that this lack of an effect may hold true at any exposure level less than that which will kill a significant number of the dams by hyperthermia (colonic temperature greater than 40 degrees C). PMID- 6909306 TI - Keeping pace with change. PMID- 6909307 TI - To endure is nothing. PMID- 6909308 TI - Coping with student nurses. PMID- 6909309 TI - Management of the child with appendicitis. PMID- 6909310 TI - Continuing education. PMID- 6909311 TI - The beat goes on: kismet. PMID- 6909312 TI - Legal restraints on the delivery of health care. PMID- 6909313 TI - Where we are going. PMID- 6909314 TI - The new Reagan health policies threaten patient care and LP/VN employment opportunities. PMID- 6909315 TI - [Evaluation of ampicillin-dicloxacillin combination (HI-56 G) in pediatric field (author's transl)]. PMID- 6909317 TI - [Methods for successful breast feeding]. PMID- 6909316 TI - [Clinical studies on serum trypsin by radioimmunoassay (author's transl)]. PMID- 6909318 TI - [Process leading to successful breast feeding and its importance in mother-child relations: a case study]. PMID- 6909319 TI - [Survey on the public awareness of the importance of breast feeding]. PMID- 6909320 TI - [Survey on mothers' knowledge and attitude to sex]. PMID- 6909321 TI - [Comparative obstetrics on man and monkeys. 12. Pregnancy of monkeys (II)]. PMID- 6909322 TI - [Letters from America. The methods of delivery in Milwaukee]. PMID- 6909323 TI - [Importance of ultrasonography at the early stage of pregnancy]. PMID- 6909324 TI - [Discussion on the "Woman's Body": on knowing one's own body]. PMID- 6909325 TI - [The Japanese and world-wild population problems]. PMID- 6909326 TI - [History of population problems and their impact on daily lives: an interview with Ms. Haruko Hashimoto, an experienced midwife at Mitaka-shi. Interview by N. Yamashita]. PMID- 6909328 TI - [Family-related problems in the age of low birth rate and low mortality]. PMID- 6909327 TI - [Family planning in Bangladesh]. PMID- 6909330 TI - [Recording of the partogram using the information derived from the monitoring system during delivery]. PMID- 6909329 TI - [Low birth rate and the modern women. A discussion]. PMID- 6909331 TI - [Letters from America. Introduction of "When a woman wants to deliver outside the hospital"]. PMID- 6909332 TI - [Comparative obstetrics of man and monkeys. 13. Pregnancy of monkeys (III)]. PMID- 6909333 TI - [Agents suppressing uterine contraction]. PMID- 6909334 TI - [High risk babies--their classification and evaluation of the risk]. PMID- 6909335 TI - [A long-term follow-up of premature infants with high risks--on the NICU management to improve their mortality]. PMID- 6909337 TI - [Water-electrolyte balance of high risk premature infants and detection of deviations]. PMID- 6909336 TI - [Detection of respiratory anomalies--respiratory deviations in high-risk premature infants and their monitoring]. PMID- 6909338 TI - [Respiratory care of premature infants with high risks and their monitoring program--cases of IRDS]. PMID- 6909339 TI - [Fluid infusion therapy of premature infants at high risk--innovation of an infusion chart]. PMID- 6909340 TI - [Improvement of the format of the nursing records in the premature and newborn infant ward]. PMID- 6909341 TI - [Emotional development and nursing care of a premature infant reared in an incubator for an extended time]. PMID- 6909343 TI - [Care of high risk babies: from the perinatal period to continued nursing]. PMID- 6909342 TI - [Nursing of neonatal hypoxia and standards for observation]. PMID- 6909344 TI - [Case conference: treatment and care of neonatal necrotizing enteritis- successful management with application of long-term ventilation, surgery, and exchange transfusion]. PMID- 6909345 TI - [Nursing care of late metabolic acidosis in premature infants]. PMID- 6909346 TI - [Emergency treatment of rupture of esophageal varices]. PMID- 6909347 TI - [Science of symptomatology. Palpitation: development of palpitation]. PMID- 6909348 TI - [Science of symptomatology. Palpitation: major conditions responsible for palpitation and their treatment]. PMID- 6909349 TI - [Science of symptomalogy. Palpitation: disability evaluation of patients with heart diseases and tachycardia and their nursing]. PMID- 6909350 TI - [Science of symtomatology. Palpitation: re-evaluation of guidance of cardiovascular patients concerning their daily activities]. PMID- 6909351 TI - [Ten basic needs of patients with respiratory tract diseases--evaluation of the current nursing technology for patients with respiratory insufficiency]. PMID- 6909353 TI - [Expectation on strengthening nursing education in the area of infection prevention]. PMID- 6909352 TI - [Bedside guidance in cardiology. 8. Congenital heart disease]. PMID- 6909354 TI - [Direction in teaching processes: starting from the "darkness"]. PMID- 6909355 TI - [On "Expectation on teaching personnel--between humanism and behaviorism" by Susan L. Carter]. PMID- 6909356 TI - [Understanding the object. Analysis of the fundamental life activities from the social aspect. (1)]. PMID- 6909358 TI - [Planning of clinical training in obstetrical nursing. (4) On training in home care]. PMID- 6909357 TI - [The current status and problems concerning the classrooms for clinical training in nursing]. PMID- 6909359 TI - [Minerva's light. A casual thought on nursing and man. (3). Beyond the realm of intelligence]. PMID- 6909360 TI - [In search of a new educational encounter. 2. Evaluation of nursing students and personalized education]. PMID- 6909361 TI - [Overcoming undue emphasis on objectivity in nursing study. (2)]. PMID- 6909363 TI - [Approaches to effective and efficient use of materials in public health nursing]. PMID- 6909362 TI - [A trial at incorporation of public health nursing education in the basic nursing education system--an outline of plans for public health nursing]. PMID- 6909365 TI - [Activities of a public health nurse. Discovery of a case of pneumoconiosis]. PMID- 6909364 TI - [A thought on patient education in infant care--a survey on mothers visiting the infant care consulting service]. PMID- 6909366 TI - [Regional care of patients with refractory diseases. Panel discussion. Home care of patients: case of muscular dystrophy in brothers]. PMID- 6909367 TI - [Regional society and home nursing - recognition of the problems and improvement of the conditions]. PMID- 6909368 TI - [Public health nurses at the Santama area (4). 40 years as a public health nurse: an interview with Ms. Kikuko Kumagaya]. PMID- 6909369 TI - [Active participation by citizens in public health activities]. PMID- 6909370 TI - [Activities of the family welfare workers in Bangladesh]. PMID- 6909371 TI - [Life style of primigravida of urban nuclear families - changes in life schedules before and after pregnancy]. PMID- 6909372 TI - [Infantile eczema and feeding methods]. PMID- 6909373 TI - [Status of dropouts of tuberculosis patients]. PMID- 6909374 TI - [Needs requiring assistance - assistance for the mothers who present difficulty in nursing]. PMID- 6909375 TI - [Psychological viewpoints in counseling on contraceptives]. PMID- 6909376 TI - [The end of an era]. PMID- 6909377 TI - [Gentle and family-centered. A report on the true meaning of a confinement conducted according to Dr. Leboyer's principles]. PMID- 6909378 TI - [Ensuring professional competence in maternity care centers]. PMID- 6909380 TI - [Care of the terminally ill patient]. PMID- 6909379 TI - [Approach to a patient with an emotional crisis due to pregnancy]. PMID- 6909381 TI - [The effect of position on the transcutaneous oxygen pressure of premature infants]. PMID- 6909383 TI - [Visit to a different kind of maternity hospital]. PMID- 6909382 TI - [Childbirth today and yesterday]. PMID- 6909384 TI - [Medical topics: controversy concerning primary health care]. PMID- 6909385 TI - [Report on the activities of the ILO]. PMID- 6909386 TI - [Current problems of clinical training]. PMID- 6909388 TI - [Nursing travel through England and Denmark]. PMID- 6909387 TI - [Iatrogenic accidents at a psychiatric hospital and the responsibility of the nursing personnel]. PMID- 6909389 TI - [Medical care in China with the primary emphasis on the public]. PMID- 6909390 TI - [Statistical file. Transitions in the statistics of the medical facilities and nursing personnel]. PMID- 6909391 TI - [Nursing education and clinical practice]. PMID- 6909392 TI - [Health and exercises for a writer. An essay]. PMID- 6909393 TI - [Unification in nursing]. PMID- 6909394 TI - [Changes in medical therapy: its effects on clinical training and the future directions]. PMID- 6909395 TI - [Relationship between in-service training and basic education - an observation on overnight training of new nurses]. PMID- 6909396 TI - [Trends and an overview on nursing students - a study on the nursing students at Kyushu University]. PMID- 6909397 TI - [Evaluation of systematized nursing planning]. PMID- 6909399 TI - [Mesothelioma in children]. PMID- 6909398 TI - [Copper content of the hair]. PMID- 6909400 TI - [Mycosis of the viscera]. PMID- 6909401 TI - [The incident at the Fujimi Gynecologic and Obstetrical Hospital: expectation on nursing. A discussion]. PMID- 6909402 TI - [The modern American professional nurse]. PMID- 6909404 TI - [Social position and recognition of the nurse in the modern nursing history in Japan]. PMID- 6909403 TI - [Reports on the activities of the ILO]. PMID- 6909405 TI - [Help extended to post-mastectomy patients - report on the American Cancer Society]. PMID- 6909406 TI - [Medical topics: controversy concerning primary health care]. PMID- 6909407 TI - [Statistical file. Fluctuations and the status of midwifery power]. PMID- 6909408 TI - [Minor ailments. An essay]. PMID- 6909409 TI - [Thoughts on the incident at the Fujimi Gynecologic and Obstetrical Hospital: a discussion]. PMID- 6909410 TI - [Medical practice and its assistance by unlicensed personnel]. PMID- 6909411 TI - [Significance of the incident at Fujimi Gynecologic and Obstetrical Hospital: the outline and aftermath of the incident]. PMID- 6909412 TI - [Malpractice suit concerning nursing]. PMID- 6909414 TI - [Myocardial magnesium and calcium]. PMID- 6909413 TI - [Profile of a nurse. Ms. Takeko Kanai, who is active in home nursing supported by a city government]. PMID- 6909415 TI - [Medical topics. Antiplatelet therapy]. PMID- 6909416 TI - The Washburn nursing curriculum: returning to school from the perspective of an educator, formerly an R.N. student. PMID- 6909417 TI - Community health nursing in Kansas. PMID- 6909418 TI - The Washburn nursing curriculum: interpreting Martha Rogers in the Land of Oz. PMID- 6909419 TI - The Washburn nursing curriculum: perspectives from Washburn graduates. PMID- 6909420 TI - The Washburn nursing curriculum: returning to school from the perspective of a registered nurse student. PMID- 6909421 TI - New nursing program begins: Bethel College. PMID- 6909424 TI - Gerontological nursing. PMID- 6909422 TI - School nursing in Kansas today. PMID- 6909423 TI - "Burnout, the inevitable professional hazard?". PMID- 6909426 TI - Implementation of research findings: St. Mary of the Plains College. PMID- 6909425 TI - Baccalaureate nursing program for generic and R.N. students: an overview of St. Mary of the Plains College. PMID- 6909427 TI - [Causes, pathophysiology and therapy of migraine]. PMID- 6909429 TI - [Current legal questions for nursing personnel]. PMID- 6909428 TI - [New function fields for pediatric nursing: proposal for structured continued education for (pediatric) nurses in the field of special education]. PMID- 6909430 TI - [Schizophrenia - heredity and environment. Strong influence of social factors - oneness of body and soul]. PMID- 6909431 TI - [Once again rickets problems in pediatric hospitals. Pediatricians want nutrition counseling and rickets prevention for Turkish children]. PMID- 6909432 TI - [The mental status of patients]. PMID- 6909434 TI - [Measures against stress. Administrative personnel in nursing services tell what is urgently needed - position of the BALK (Federal Union of the Study Group of Administrative Nursing Personnel)]. PMID- 6909433 TI - [Causes and therapy of gonarthrosis]. PMID- 6909435 TI - [Psychomotor aspects for children with minimal cerebral movement disorders]. PMID- 6909436 TI - [Infections in the hospital]. PMID- 6909438 TI - [Anxiety about the fear of the patient]. PMID- 6909437 TI - [Foot mycosis - a civilization disease?]. PMID- 6909439 TI - [A crisis mood in nursing: overburdened, apathetic and disenchanted]. PMID- 6909440 TI - [Not only the educators are worried about education. Nursing Congress - desire for a nursing board]. PMID- 6909441 TI - Pediatric-based assessment: children with school problems. AB - Twenty-one children with school problems underwent pediatric assessment within a university hospital primary care clinic. Assessment included history-taking facilitated by parent and teacher questionnaires, physical examinations, vision and hearing screening and neurodevelopmental examination. For 11 of the children, psychoeducational assessment was also obtained. Parent and school personnel were interviewed 2 to 6 months following assessment to determine implementation rates for recommendations. Overall, 66% of parent recommendations were implemented, including 72% of medical, 58% of mental health and 64% of educational recommendations. Seventy-two percent of school recommendations were implemented. Interdisciplinary evaluation as compared to pediatric-based assessment alone resulted in a greater number of recommendations generated (p less than .05) and a higher percentage of school recommendations implemented (p less than .01). Implementation rates for school recommendations were greater for young children (p less than .01). This study supports the usefulness of pediatric-based assessments for school problems and documents the advantages of an interdisciplinary approach to such children. PMID- 6909442 TI - Evaluation of a comprehensive cardiovascular curriculum. PMID- 6909443 TI - My daughter wants to be a nurse: occupational stereotyping in health textbooks. PMID- 6909444 TI - Relation of intensity and frequency of student drug use to reasons for use. PMID- 6909445 TI - Smoking awareness and practices of urban pre-school and first grade children. PMID- 6909446 TI - Child safety programs: implications affecting use of child restraints. AB - Automobile deaths have been identified as the leading cause of death for children between the ages of one and fourteen. Those children who are unrestrained as passengers are at particularly high risk to injury and death. School health and safety programs need to include an understanding of this problem and implement efforts to increase restraint usage. A study of parental seatbelt and child passenger restraint use was conducted to identify frequency of use and behavioral and attitudinal factors influencing use of child restraints. Self-reported data of driver seatbelt use at all times was 19.0%, and the use of a child restraining device was 49.6%. Data recorded in a previous observational study noted a driver seatbelt usage rate of 14.2% and use of a child restraining device at 25.6%. Major reasons for non-use of seatbelts by drivers included discomfort and restricted movement. Reasons for non-use of child restraints focused upon the dislike and discomfort of the child for the restraint. PMID- 6909447 TI - The effects of a heart health education workshop. PMID- 6909448 TI - Controlling stress & tension: biomedical and psychometric evaluation of programs at the University of Maryland. PMID- 6909449 TI - Effects of death education on nursing students' anxiety and locus of control. PMID- 6909451 TI - [Uterine cancer]. PMID- 6909450 TI - Progress report of the Role Delineation Project. PMID- 6909452 TI - [Diagnosis and treatment of uterine cancer]. PMID- 6909453 TI - [Nursing process for a patient with uterine cancer]. PMID- 6909454 TI - [Evaluation of nursing process for a patient with uterine cancer. Discussion]. PMID- 6909455 TI - [Aspiration as a therapeutic measure]. PMID- 6909457 TI - [Aspiration and nursing in surgery of breast cancer]. PMID- 6909456 TI - [Keypoints in nursing care during aspiration]. PMID- 6909458 TI - [Nursing of patients undergoing inhalation therapy]. PMID- 6909459 TI - [Assistance of an aphasic patient and the nurse--evaluation of communication capacity of the aphasic patient and nursing]. PMID- 6909461 TI - [Nursing of an emergency case with acute angina]. PMID- 6909460 TI - [Assistance for the mother after delivery of a premature infant--motivation for development of affection toward the child. (2)]. PMID- 6909462 TI - [Personal notes on nurses]. PMID- 6909463 TI - [Cholelithiasis]. PMID- 6909464 TI - [Diagnosis and surgical therapy of cholelithiasis]. PMID- 6909465 TI - [Nursing process for a patient with cholelithiasis]. PMID- 6909466 TI - [Evaluation of the nursing process for a patient with cholelithiasis]. PMID- 6909467 TI - [Body temperature: its significance and methods of determination]. PMID- 6909468 TI - [Recording and control of body temperature in the ICU]. PMID- 6909470 TI - [Significance of case studies]. PMID- 6909469 TI - [Body temperature determination and care in a pediatric ward]. PMID- 6909471 TI - [Assistance for a child undergoing extended hemodialysis and the nursing personnel]. PMID- 6909472 TI - [Experience in nursing of premature infants]. PMID- 6909474 TI - [Obstetrical nursing during the puerperial period]. PMID- 6909473 TI - [Effects of hospitalization on children]. PMID- 6909475 TI - [Prevention of adult diseases starting in childhood]. PMID- 6909477 TI - Night sleep of children in a hospital. Part II: sleep disruption. PMID- 6909479 TI - Postpartum depression and mothers of infant twins. PMID- 6909478 TI - Collecting information: a way to cope with cardiac surgery. PMID- 6909476 TI - Infant feeding and anticipatory care: supporting the adaptation of parents to their new babies. PMID- 6909481 TI - Australian Kidney Foundation. PMID- 6909480 TI - Involvement-- "what's a nice person...?". PMID- 6909484 TI - 'The worst of all possible worlds.'. PMID- 6909482 TI - Pastoral care - the intrusion of pastoral services. PMID- 6909483 TI - Case history midwifery: abruptio placenta. PMID- 6909486 TI - Graduation address Canterbury Hospital 1980. PMID- 6909485 TI - The needs of the user. PMID- 6909487 TI - Suffering adults reduced to naughty children. PMID- 6909488 TI - Cooperative education: its relevance for basic nursing education in colleges of advanced education. PMID- 6909489 TI - Babies, births, basics. PMID- 6909490 TI - Isolation of mothers in the community. PMID- 6909492 TI - Report on observation visits to paediatric hospitals and units in Great Britain and the United States July-October, 1980. PMID- 6909491 TI - Pastoral care. PMID- 6909493 TI - Updating intravenous injection technique. PMID- 6909494 TI - Post natal follow-up slip pilot survey. PMID- 6909496 TI - Manpower utilisation and quality control. PMID- 6909497 TI - Conceptual frameworks used in baccalaureate and master's degree curricula. PMID- 6909498 TI - Faculty research development grants: a follow-up report. PMID- 6909499 TI - Effect of Ro 4-1284 on audiogenic seizure susceptibility and intensity in epilepsy-prone rats. PMID- 6909501 TI - [Care of severely burned patients]. PMID- 6909500 TI - New directions in nursing ethics. PMID- 6909502 TI - [Prevention and treatment of frostbite]. PMID- 6909504 TI - [Work of the nurse in a cosmetology establishment]. PMID- 6909503 TI - [Prevention of obesity]. PMID- 6909506 TI - [Holder for the dental x-ray film]. PMID- 6909505 TI - [Spirographic method of studying lung function]. PMID- 6909507 TI - [Work planning for the chief ward nurse]. PMID- 6909508 TI - [Work organization for district nurses]. PMID- 6909509 TI - [Pollinosis (hay fever)]. PMID- 6909510 TI - [Mortality and lethality indices (nature and characteristics of the calculations)]. PMID- 6909512 TI - [Taking of drugs before and after meals]. PMID- 6909511 TI - [Scientific organization of work in the physical therapy department (office)]. PMID- 6909513 TI - [Work of a district nurses' council]. PMID- 6909514 TI - [Allergic diseases of the ear, throat and nose]. PMID- 6909515 TI - [Diseases of the eyelashes]. PMID- 6909516 TI - [Bronchiole spasm in anesthesiological practice]. PMID- 6909518 TI - [Physiotherapy in the neurological syndromes of cervical osteochondrosis]. PMID- 6909517 TI - [Tietze's syndrome]. PMID- 6909519 TI - [Medical work expertise and the rehabilitation of patients with peripheral facial nerve lesions]. PMID- 6909520 TI - [Use of antibiotics in ophthalmic practice]. PMID- 6909521 TI - [Care of the subclavian catheter in resuscitation patients]. PMID- 6909522 TI - [Endoscopic study, an important diagnostic method]. PMID- 6909523 TI - [Clamp for the tourniquet]. PMID- 6909524 TI - [Mobile washstand]. PMID- 6909525 TI - [Device for flow-through systems irrigation]. PMID- 6909526 TI - [Modification of gas-bubble baths]. PMID- 6909527 TI - [Stand for sterilizing bloodletting needles]. PMID- 6909528 TI - [Patient participation in carrying out a therapeutic and protective regimen]. PMID- 6909529 TI - [Information for the nurse on prescriptions]. PMID- 6909531 TI - [Stomach bezoars]. PMID- 6909530 TI - [Operating tables]. PMID- 6909532 TI - [What one should know about cancer]. PMID- 6909533 TI - [Treatment of chronic suppurative otitis]. PMID- 6909534 TI - [Films on health and their influence]. PMID- 6909535 TI - [Organization of educational work among paramedical and auxilliary personnel]. PMID- 6909536 TI - [Let us talk about courtesy]. PMID- 6909538 TI - Nursing saved. PMID- 6909537 TI - [Congenital fistulas and cysts of the ENT organs]. PMID- 6909539 TI - Guidelines for hospital nursing privileges for nurses not employed by hospitals developed by The Michigan Joint Practice Commission. PMID- 6909540 TI - Reducing the danger of asphyxia. PMID- 6909541 TI - Direct entry method of training midwives in three countries: 3. France. PMID- 6909542 TI - Effect of present patterns of maternity care on the emotional needs of mothers: Part 1. PMID- 6909543 TI - What's wrong with our library services? PMID- 6909545 TI - Gynecologic oncology nursing. PMID- 6909544 TI - Menopause. PMID- 6909546 TI - The nurses' role in electronic fetal monitoring. PMID- 6909547 TI - Irradiation therapy for gynecology patients. PMID- 6909548 TI - Infection control for the obstetric patient and the newborn infant. PMID- 6909549 TI - The nursing process. PMID- 6909550 TI - The total care of a patient within the operating department. PMID- 6909551 TI - DHSS advice on some aspects of disinfection and sterilization. PMID- 6909552 TI - Transfer-RNA: the early adaptor. AB - Evolutionary history of tRNA is studied by comparative sequence analysis of two specified tRNA's at various phylogenetic levels and of tRNA families within four different species. Criteria are developed that allow 1) to distinguish between convergent and divergent evolution, 2) to determine the mechanism of divergence and 3) to estimate the degree of randomization of the variable parts of the sequences. The conclusion of these investigations is that tRNA's represent ancient molecules that existed in the form of a mutant distribution prior to their integration into genomes. PMID- 6909553 TI - Pre-treatment patient education for dialysis. PMID- 6909554 TI - Hypotension during hemodialysis: physiological mechanisms involved. PMID- 6909555 TI - Nursing goals in the patient with membranous nephropathy. PMID- 6909556 TI - Algorithms for the dialysis nurse. PMID- 6909557 TI - Facility report: Saint Margaret Hospital. PMID- 6909558 TI - Dialysis: the nephrology nurse/patient relationship. PMID- 6909559 TI - Legislative log: a bit of housecleaning. PMID- 6909560 TI - [Administration of public health nursing services]. PMID- 6909563 TI - [For the period 1981-1985: working program of the General Council of the ATS (Technical Health Assistants)]. PMID- 6909564 TI - [Basic concepts of public health and primary care]. PMID- 6909562 TI - [Educational plan in public health nursing]. PMID- 6909561 TI - [Educational strategy in public health]. PMID- 6909565 TI - [Applied research in nursing and public health. Technics of data collection and statistical evaluation of results in the field of primary health care]. PMID- 6909566 TI - [Technics of case finding and surveillance of groups at risk. Potential role of the Technical Health Assistant (ATS) in public home care services]. PMID- 6909567 TI - [Tirajana's health center (Canary Islands)]. PMID- 6909568 TI - [Community health nursing in Spain]. PMID- 6909569 TI - [Interview with Gonzalo Sampascual, Secretary of the Graduate Course. The National University of Extended Education clarifies uncertainties]. PMID- 6909570 TI - [Health services in Colombia]. PMID- 6909572 TI - On the scene: Beth Israel Hospital. PMID- 6909571 TI - Primary nursing revisited. Part I. PMID- 6909573 TI - On the scene: Beth Israel Hospital. The development of a professional practice system. PMID- 6909574 TI - On the scene: Beth Israel Hospital. Group anxiety precipitated by primary nursing. PMID- 6909575 TI - On the scene: Beth Israel Hospital. Preventing isolation in primary nursing. PMID- 6909576 TI - On the scene: Beth Israel Hospital. Night nurses can be primary nurses. PMID- 6909577 TI - On the scene: Beth Israel Hospital. Evaluation research: a quality assurance program. PMID- 6909578 TI - On the scene: Beth Israel Hospital. A centralized staffing resource system. PMID- 6909579 TI - On the scene: Beth Israel Hospital. Development of group cohesiveness. PMID- 6909580 TI - Primary nursing: more data. PMID- 6909581 TI - On the scene: Beth Israel Hospital. The role of the head nurse. PMID- 6909582 TI - Clinical ladders and primary nursing: the wedding of the two. PMID- 6909583 TI - Is primary nursing the answer? PMID- 6909584 TI - The legal implications of informed consent. PMID- 6909586 TI - Buyer beware: the RN as baccalaureate student. PMID- 6909585 TI - On the scene: Beth Israel Hospital. From line to staff: a change in concept. PMID- 6909587 TI - Backwoods nursing. PMID- 6909588 TI - The teaching of nursing research--Part III: a comparison of teaching strategies. PMID- 6909589 TI - The economics of health care and the future of nursing. PMID- 6909591 TI - Guiding your patient... a step at a time... through a colonoscopy. PMID- 6909592 TI - Nursing diagnosis. How to define the problem can be half the solution. Here's how to make diagnostic language work for you. PMID- 6909593 TI - Caring for the cardiac cripple. Nursing grand rounds. PMID- 6909594 TI - Teaching patients to cope with psoriasis. The unshared disease. PMID- 6909595 TI - When your patient's still in pain don't just do something: sit there. PMID- 6909597 TI - Defibrillation when and how to use it. PMID- 6909598 TI - Test your knowledge of caring for the woman with cancer. PMID- 6909596 TI - Solving chest tube problems. PMID- 6909599 TI - Zomepirac sodium. Learn about this potent new non-narcotic analgesic. PMID- 6909600 TI - Believe it or not: conflict can be healthy once you understand it and learn to manage it. PMID- 6909601 TI - Diagnostic tests. Two intestinal tests: one oral, one anal. PMID- 6909602 TI - Food and drugs: managing the right mix for your patients. PMID- 6909603 TI - Gauging abdominal girth accurately. PMID- 6909604 TI - Diagnosing your patient's strengths. PMID- 6909605 TI - From I.V. to P.O. titrating your patient's pain medication. PMID- 6909606 TI - Organize your workday for more effective discharge planning. PMID- 6909607 TI - Ambulatory nursing: your patient's discharge plan--does it include home-care referral? PMID- 6909608 TI - Challenge: Martin's problem--can you figure it out? PMID- 6909609 TI - Test your knowledge of congestive heart failure. PMID- 6909610 TI - Caring for someone close to you. PMID- 6909612 TI - In the beginning... the new academic administrator. PMID- 6909611 TI - Congruence of nurse-patient expectations regarding nursing intervention in pain. PMID- 6909613 TI - Take a chance on change! PMID- 6909614 TI - Role discrepancy: implications for nursing leaders. PMID- 6909615 TI - Joint practice: a model - the origin, implementation and evaluation of a discharge unit. PMID- 6909616 TI - Res ipsa loquitur (the thing speaks for itself) PMID- 6909617 TI - Who's who among nursing leaders. Interview by Dorothy F. Corona. PMID- 6909618 TI - A new role for Maude Storey. Interview by Barbare Sim Rogers. PMID- 6909619 TI - Voice of the ward sister: talking to Desmond O'Grady.. Interview by Celia Fairbrother. PMID- 6909620 TI - Stress ... in the community. PMID- 6909621 TI - Education means teamwork. PMID- 6909622 TI - Psychiatric nurses meet. PMID- 6909623 TI - Counselling patients with cancer. PMID- 6909624 TI - Legal notes: confidentiality in nursing. PMID- 6909625 TI - Positive discipline at work. PMID- 6909627 TI - Using equipment effectively. PMID- 6909626 TI - Commissioning a new general hospital. PMID- 6909629 TI - Nursing in Pakistan. A new training school is opened. PMID- 6909628 TI - Voice of the ward sister. Interview by Celia Fairbrother. PMID- 6909630 TI - Legal notes: selection for redundancy. PMID- 6909631 TI - Is critical-care nursing for you? PMID- 6909632 TI - Temporary agencies offer poor solution to staffing problems. PMID- 6909633 TI - Burn center: burn unit nurses treat mental and physical pain. PMID- 6909634 TI - Spotlight on AACN: the American Association of Critical Care Nurses. PMID- 6909635 TI - Who takes CE and why? PMID- 6909636 TI - New "movement synthesis" for nurses and patients. PMID- 6909637 TI - Legal nurse. PMID- 6909638 TI - Nurses in action. PMID- 6909639 TI - Career milestone: finding your first job. PMID- 6909640 TI - Supplemental staffing and home health care: solutions to dropping out. PMID- 6909641 TI - Legal nurse: the nurse as a witness. PMID- 6909642 TI - Non-traditional careers for nurses. PMID- 6909643 TI - Epidemiology: industry, occupation and the chemical environment. PMID- 6909644 TI - Ergonomics: noise and vibration control. PMID- 6909645 TI - Solidarity: fair loss but a lot gained. PMID- 6909646 TI - Safety: planning a hygiene survey. PMID- 6909647 TI - Building up hygiene and safety. PMID- 6909648 TI - Alcohol dependency: spotting the tell-tale signs at work. PMID- 6909649 TI - Occupational first aid-- a personal view. PMID- 6909650 TI - Ergonomics: light and colour. PMID- 6909651 TI - Safety: legal restrictions on women at work. PMID- 6909652 TI - Hydrotherapy: its history, theory and practice. PMID- 6909653 TI - Safety: what does responsibility mean? PMID- 6909654 TI - Hungary's approach to safety. PMID- 6909655 TI - Ergonomics: thermal comfort. PMID- 6909656 TI - Occupational health nursing in Australia. PMID- 6909657 TI - Occupational health nursing in the United States. PMID- 6909658 TI - Occupational health nursing in Sweden. PMID- 6909659 TI - Occupational health nursing in The Netherlands. PMID- 6909660 TI - Soaring through time zones. PMID- 6909661 TI - Occupational health nursing in Finland. PMID- 6909662 TI - Practical methods of how to examine the external eye. PMID- 6909664 TI - Simple nursing procedures for the occupational health nurse. PMID- 6909663 TI - Common toxic effects of systemic drugs on the eye. PMID- 6909666 TI - Glaucoma screening. PMID- 6909665 TI - Some common visual symptoms: what they mean and what to do about them. PMID- 6909667 TI - Chemical and thermal burns of the eye. PMID- 6909668 TI - When to use topical steroids in the treatment of eye disease. PMID- 6909669 TI - The management of corneal abrasions and corneal foreign bodies. PMID- 6909670 TI - Practical anatomy and physiology of the eye and orbit. PMID- 6909671 TI - Nursing's involvement in the health planning process. PMID- 6909673 TI - The Brazelton Neonatal Behavioral Assessment Scale: implications for intervention. PMID- 6909672 TI - Child car seats: a must for safety. PMID- 6909674 TI - Clinical uses of the Brazelton Neonatal Behavioral Assessment Scale in nursing practice. PMID- 6909676 TI - Child discipline: what we know and what we can recommend. PMID- 6909677 TI - Recertification: a systematic program of continuing education. PMID- 6909675 TI - Parents of asthmatic kids (PAK): a successful parent support group. PMID- 6909679 TI - Not for parents only: "Malcomb the miserable learns about medicines". PMID- 6909680 TI - Pediatric management problems: bacteremia. PMID- 6909678 TI - Teething. PMID- 6909681 TI - Tampons, teen-agers and toxic shock. PMID- 6909682 TI - Are surveillance of resistant enteric bacilli and antimicrobial usage among neonates in a newborn intensive care unit useful? AB - From March 1976 through December 1978, the prevalence of ampicillin- and gentamicin-resistant enteric bacilli was monitored in fecal cultures of neonates in an intensive care unit. Substantial fluctuations in colonization rates were observed which did not correlate with the occurrence of sepsis due to these organisms nor with variations in antibiotic use. This experience suggests that the availability of these surveillance data did not result in more effective control of neonatal sepsis due to enteric bacilli. PMID- 6909684 TI - More dialogue needed among health care professionals. PMID- 6909683 TI - Indomethacin and its effect on renal function and urinary kallikrein excretion in premature infants with patent ductus arteriosus. AB - In the course of a double-blind trial of intravenous indomethacin therapy in premature infants with patent ductus arteriosus, renal function and urinary kallikrein were studied in 21 infants following one dose of either saline placebo or indomethacin. Ten infants were assigned to the control group and 11 were in the indomethacin group. Significantly lower urine output, fraction excretion of sodium, fraction excretion of chloride, and urinary kallikrein were noted by 45%, 59%, 63%, and 51%, respectively, in the indomethacin group as compared to the control group. There was a concomitant decrease in serum sodium concentration (P less than .05) at 24 hours following indomethacin therapy. No significant difference in glomerular filtration rate was seen between the control group and the indomethacin-treated infants. PMID- 6909685 TI - The public image of the nurse: is it changing? PMID- 6909686 TI - Position statement on national shortage of nurses. PMID- 6909688 TI - Faculty practice as one component of the faculty role. PMID- 6909687 TI - Cognitive dissonance: interpreting and implementing faculty practice roles in nursing education. PMID- 6909689 TI - Faculty practice in a nursing center: an integrated model. PMID- 6909690 TI - Evaluating the practice component for faculty rank and tenure. PMID- 6909691 TI - Evaluating the clinical performance of faculty: fact or fantasy? PMID- 6909692 TI - Promoting collaboration/unification models for nursing education and service. PMID- 6909693 TI - Economic realities of faculty practice. PMID- 6909695 TI - Faculty practice: models, methods and madness. PMID- 6909694 TI - Future perspectives for faculty practice--credibility, visibility, accountability. PMID- 6909696 TI - Cognitive dissonance: an examination of CBHDP stated beliefs and their effect on educational programs. PMID- 6909698 TI - Can nursing be taught at liberal arts college? PMID- 6909697 TI - Faculty educational preparation- what type? How much? How utilized? PMID- 6909699 TI - The conceptual framework as a basis for curriculum development in baccalaureate programs. PMID- 6909702 TI - Are conceptual frameworks needed in nursing curricula? PMID- 6909700 TI - Nursing programs and their institutional settings. PMID- 6909701 TI - How sacred are the sacred cows? PMID- 6909703 TI - Faculty educational preparation: a case for practice what you teach. PMID- 6909704 TI - Measurement and evaluation in nursing education. PMID- 6909705 TI - Nursing data book 1980: statistical information on nursing education and newly licensed nurses. PMID- 6909706 TI - Curriculum design for associate degree nursing programs: teaching and evaluation in the classroom. PMID- 6909707 TI - Environmental Sanitation Division; Bureau of Health and Medical Services, Ministry of Health. Food poisoning. PMID- 6909708 TI - Primary health care. PMID- 6909710 TI - Of MPH people and watermelons. PMID- 6909709 TI - Graduation message. PMID- 6909711 TI - Diarrhoeal Diseases Control Programme. World Health Organization/AHRTAG. PMID- 6909712 TI - Oral rehydration therapy: the Philippine field experience. PMID- 6909713 TI - The Human Development Council of the Bohol Provincial Hospital. PMID- 6909714 TI - Home visit, a challenge to public health nurse. PMID- 6909715 TI - "Because there are isolated islands, far-flung barrios and high mountain peaks". PMID- 6909716 TI - On the status of schools of nursing in the Ministry of Health. A position paper. PMID- 6909717 TI - In defense of the traditional nurse. PMID- 6909718 TI - Political factors influencing nursing practice. PMID- 6909719 TI - Nationalizing health care: a humanitarian approach. PMID- 6909720 TI - National health service: rationale and implementation. PMID- 6909721 TI - The therapeutic use of pets. PMID- 6909722 TI - The women's movement and the nurse practitioner's sense of role. PMID- 6909723 TI - The nursing profession viewed as a political pressure group: selected review of the literature. PMID- 6909724 TI - Nurses and political action: the legacy of sexism. PMID- 6909725 TI - Stress, social support, and the transition to fatherhood. AB - Over the past ten years, nurses have shown increasing interest in understanding and assisting men in their transition to fatherhood. Inadequate data and lack of a framework for interpreting diverse studies have hindered the development of appropriate intervention strategies. In this article, a paradigm from the field of stress research is adapted to the transition to fatherhood. The new paradigm organizes and integrates the factors that impact on a man's experience of becoming a father. The utility of this paradigm in generating theory and hypotheses for future research is illustrated by fully exploring one of the potential variables impacting on fatherhood, i.e., social support. Through this process a better theoretical understanding of social support as well as a guide to future inquiry concerning fatherhood is acquired. PMID- 6909726 TI - Single custodial fathers and the parent-child relationship. AB - This exploratory study was designed to investigate the relationship between selected background characteristics of single fathers and the quality of existing parent-child relationships, to see if background characteristics could be used to predict father-child nurturance. Correlations between the social class of the fathers and the history of their relations with their own fathers were not statistically significant. However, the reason for their having custody of their children (seeking it or assenting to it) appears to be worth further investigation. The results of this study have ramifications for nursing. Nursing educators need to acknowledge the advent of the single-family structure (as well as other alternative family configurations different from the traditional nuclear family) when planning the curriculum for nursing students. The increasing involvement and importance of the male as a parent must be given due consideration. Married fathers and single fathers (with or without custody) can and do play an important role in the lives of their children. Let us not lose sight of this important member of the parenting team. PMID- 6909727 TI - Preferences of hospitalized adolescents for information providers. AB - The purposes of this study were to determine: (1) what are the preferences of hospitalized adolescents for information providers (parent(s), health professionals, or both parent(s) and health professionals); and (2) criteria to predict preferences, based on significant relationships between preferences and selected variables (sex, illness, length of illness, question topics, parental preference for information providers, length of hospitalization, number of previous hospitalizations, and age). A nonexperimental survey of 40 hospitalized adolescents utilized questionnaires to identify preferences of adolescents and 25 parents. Preferences were related to adolescent age and question topic. Age was statistically significant but the other variables were not. Adolescent preferences and that of their parents varied widely. Anecdotal information presented clarification of adolescent and parental preferences. The study results demonstrate that hospitalized adolescents have preferences for information providers and are willing to state those preferences when asked. Health professionals need to weigh these preferences with those of their own when delivering information to hospitalized adolescents. Replication of the study and variations of the design are suggested for further research. PMID- 6909728 TI - Moving the patient in bed: effects on intracranial pressure. AB - Intracranial pressure (ICP) was measured in 20 patients before and after each of eight nursing care activities: turning the body to four positions, passive range of motion (arm extension and hip flexion), and rotation of the head to the right and to the left. Technically usable data was available for 18 patients. Mean ICP increased for at least five minutes in all patients after one of the four turns and in 88 percent after half the turns. Change in mean ICP with one of a pair of lateral or supine turns was strongly predictive of the direction of change (increase or decrease) of the other turn of the pair. Large increases in ICP occurred in the five patients for whom head rotation was done, while there was minimal change in ICP with both passive range of motion procedures. A cumulative increase in ICP occurred with activities spaced 15 minutes apart, regardless of the nature of the activity. No cumulative increase in ICP was found with procedures spaced at least one hour apart. PMID- 6909729 TI - Effectiveness of teaching in the rehabilitation of patients with chronic bronchitis and emphysema. PMID- 6909730 TI - Friendship patterns and altruistic behavior in preadolescent males and females. PMID- 6909731 TI - The Nurse Practitioner Rating Form. Part I: Conceptual development and potential uses. AB - Most research and evaluation studies of nurse practitioner practice have used data collection instruments developed for that specific study, choosing and defining variables of interest to them and developing ad hoc measurement instruments with psychometric properties that are largely unknown. The primary focus of such studies and the instruments used in them has been on activities related to the assessment and management of medical problems. Such focus in the early studies is understandable, since these are the activities that have been added to the traditional nursing functions to form the nurse practitioner role. However, the nursing components of the role, such as patient teaching and attention to patients' psychosocial needs, have not been adequately studied. The Nurse Practitioner Rating Form (NPRF) was designed specifically to measure both the medical and nursing components of the nurse practitioner role. PMID- 6909732 TI - Measuring adjustment in chronically ill clients in community mental health care. An assessment of the Psychological Mental Health Index. PMID- 6909733 TI - Structure vs. people in primary nursing: an inquiry. AB - This paper raises the question, "Is it the structure or the competency of the nursing staff that improves the quality of primary nursing over team nursing?" In the study an all-RN model of primary nursing was compared to a team nursing care system. The nursing competency scores of registered nurses on the two units were equalized through six months of continuing education and staff development programs, and the nursing competencies and the quality of patient care were measured by Slater and Qualpac scores, respectively. Although the primary nursing unit scored higher than the team unit on five out of six subscales, the scores were statistically significant (p = .06) only on one, the communications subscale. Results of this study were compared to Felton's study, which found primary nursing units had a more competent nursing staff and higher Qualpac scores. The comparison suggests that nursing competencies may be a stronger contributing factor to the quality of care than is the structure of primary nursing. PMID- 6909734 TI - Nursing process, student attributes, and teaching methodologies. AB - This study investigated the relationship among methodologies used in teaching the nursing process, nursing students' ability to use nursing process, and the following student attributes of: field-related perceptual functioning, impulsiveness, locus of control, convergent-divergent thinking ability, and scholastic aptitude. Data were collected from 201 students at the beginning and at the end of their first clinical nursing course in six institutions. Mean scores on the Group Embedded Figures Test, Different Uses Test, and Inference Test increased significantly. The most-used teaching methodology was teacher dominated presentation; the least-used, individual conference. Findings regarding methods were based on replies from 77 faculty teaching the clinical course. A significant predictive relationship was found between the ability to use nursing process and inference ability, locus of control, and minimal time spent in small group discussion. PMID- 6909736 TI - Methodology corner: know thy data. PMID- 6909735 TI - Toward an explanatory model of nursing performance. AB - This article suggests a general substantive framework which may be used to integrate conceptually the numerous strands of research conducted in the area of nursing performance. A model which employs the variable-blocking technique discussed by Blalock is presented. Examples--in terms of the model--are given of aspects of nursing performance which have been intensively researched as well as areas which have received limited attention but hold promise. The issue of methodologies used in performance research is addressed. Three multivariate analytical techniques (factor mapping, canonical correlation, and structural equation models), which could be brought to bear on relatively complex performance data and which could prove useful for a wide range of substantive problems, are discussed. PMID- 6909737 TI - Pressure sores. 4. Mechanical devices (continued). PMID- 6909738 TI - An integrated SRN/RMN course--1. A future for nursing training? PMID- 6909739 TI - Gardens galore. PMID- 6909740 TI - Vital elements of nursing care: standards of care. PMID- 6909741 TI - Marathon man. PMID- 6909742 TI - Talking points 12. Oh, Elsie, you're having some difficulty. PMID- 6909744 TI - A cerebrovascular accident following a mitral valve replacement. PMID- 6909743 TI - Biorhythms in medicine-1. PMID- 6909745 TI - Oestrogen receptor and breast cancer. PMID- 6909746 TI - Implementing the nursing process at a unit for mentally handicapped children. PMID- 6909747 TI - Communication in nursing--3. Student nurses' construction of nursing: a discussion of a qualitative method. PMID- 6909748 TI - A psychiatric sister's ABC - 7. PMID- 6909750 TI - The nurse and the patient. Communication skills: the geography of encounter. PMID- 6909749 TI - Continuing care in the NHS at home and in hospital. PMID- 6909752 TI - What is professionalism? PMID- 6909751 TI - An integrated SRN/RMN course-2. A survey: what happens to integrated nurses? PMID- 6909753 TI - Relevant research. PMID- 6909754 TI - Patient participation - a new approach to primary health care. PMID- 6909756 TI - Communication skills: it's the way that you do it. PMID- 6909755 TI - Managers v. teachers: a plague on both your houses. PMID- 6909757 TI - Don't be shocked. PMID- 6909758 TI - Community nursing care study: decubitus ulcer. PMID- 6909759 TI - Biorhythms in medicine -2. PMID- 6909760 TI - The impact of afterloading machines in the treatment of gynaecological cancer. PMID- 6909761 TI - Drug level monitoring in children. PMID- 6909762 TI - Who has the best to offer migraineurs? PMID- 6909763 TI - A psychiatric sister's ABC--8. PMID- 6909764 TI - An aspect of infection control. PMID- 6909765 TI - Educating the professional nurse of tomorrow...today. PMID- 6909766 TI - Quest: continuing assessment. The General Nursing Council and continuing assessment. PMID- 6909767 TI - Quest. Continuing assessment. PMID- 6909768 TI - Homeless men in Oxford--1. PMID- 6909769 TI - Quest: continuing assessment. 1. The relationship between the student and the employee: a personnel approach to the employment of learners. PMID- 6909771 TI - Systems of life no 77. Digestive system--3. Abdomen. Palpation. Percussion. PMID- 6909770 TI - Quest. 2. Continuing assessment and the fieldwork teacher. PMID- 6909772 TI - The Sorrento story. PMID- 6909773 TI - Agents of change. Bringing about organizational changes. PMID- 6909774 TI - Talking points. 13. Communication skills. PMID- 6909775 TI - Head injuries. 1. Advances in care during the past decade. PMID- 6909776 TI - Clinic booklets: help or hindrance in patient education? PMID- 6909777 TI - Communication in nursing--5. A view of ethics. PMID- 6909778 TI - The bridgebuilders' guide--3. Spacing and touching and hugging. PMID- 6909779 TI - A psychiatric sister's ABC--9. PMID- 6909780 TI - An outbreak of streptococcal infection in a children's ward. PMID- 6909781 TI - Child abuse and its prevention a behavioural approach. PMID- 6909782 TI - Homeless men in Oxford-2. PMID- 6909783 TI - Nursing and the infection control nurse. PMID- 6909784 TI - Pressure sores. 5. Topical applications and wound agents. PMID- 6909785 TI - Professional development. PMID- 6909786 TI - Creative day care. PMID- 6909787 TI - Diabetes mellitus--short-stay treatment in a specialised unit. 2. Stabilisation of a patient with maturity onset diabetes. PMID- 6909788 TI - Blood glucose monitoring devices for diabetic children at home. PMID- 6909789 TI - Nursing care study: ulcerative colitis. PMID- 6909790 TI - Head injuries. 2. Advances in diagnostic equipment. PMID- 6909791 TI - Ready for home? PMID- 6909793 TI - A psychiatric sister's ABC-10. PMID- 6909792 TI - Communication in nursing. 6. Experiences of a new staff member. PMID- 6909795 TI - Integrated study in student nurse training. PMID- 6909794 TI - Talking points. 14. Communication skills. PMID- 6909796 TI - A case for action. PMID- 6909797 TI - A considerable expert. Interview by Andrew Cole. PMID- 6909798 TI - Communication skills. Talking points 15. PMID- 6909800 TI - Toxic epidermal necrolysis. PMID- 6909799 TI - Nursing care study: the mask of deafness. PMID- 6909801 TI - A psychiatric sister's ABC--11. PMID- 6909803 TI - Objective test questions. Advice to learners. PMID- 6909802 TI - A psychologist's approach to individuals with special needs. PMID- 6909804 TI - Thinking about tomorrow's patient. Interview by Alison Dunn. PMID- 6909805 TI - The community that helped itself. PMID- 6909806 TI - Nursing care study: cataract extraction under local anaesthesia. PMID- 6909807 TI - Original British trials on the functional bracing of Colles' fractures. PMID- 6909808 TI - Production of a videotape. PMID- 6909809 TI - So you think you know about counselling? PMID- 6909810 TI - Social skills and personal effectiveness training for student nurses. PMID- 6909811 TI - A psychiatric sister's ABC-12. PMID- 6909812 TI - Communication skills: talking points. 16. Doctor does not tell you much, does he? PMID- 6909813 TI - Letter from America. PMID- 6909814 TI - A patient with a difference. PMID- 6909815 TI - Performance appraisal tests for staff nurses. PMID- 6909817 TI - ZIMCORD: let's build Zimbabwe together. PMID- 6909816 TI - The nurse and patient: communication skills. Role and the presentation of self. PMID- 6909818 TI - Whooping cough vaccine in perspective. PMID- 6909819 TI - Maybury. PMID- 6909820 TI - Haemodialysis-1. PMID- 6909821 TI - Nursing care study: Lyell's syndrome. PMID- 6909822 TI - A psychiatric sister's ABC - 13. PMID- 6909823 TI - Haven of hope. PMID- 6909824 TI - The bridgebuilder's guide--5. Role playing for nurses. PMID- 6909825 TI - Communication skills: talking points.17. Something smells a bit suspicious. PMID- 6909826 TI - Written English. PMID- 6909828 TI - Ward learning climate and student nurse response. PMID- 6909827 TI - Systems of life No 78. Systems and signs. Digestive system - 4. Anus and rectum. PMID- 6909829 TI - Haemodialysis-2. PMID- 6909830 TI - Communication skills: talking points 18. Come on, say yes. PMID- 6909831 TI - No longer residential. PMID- 6909832 TI - Larger than life. Interview by Alison Dunn. PMID- 6909833 TI - The formulation of a district laundry policy. PMID- 6909834 TI - The hospital laundry bag. PMID- 6909835 TI - Nursing care study: a young patient with extensive pneumococcal pneumonia. PMID- 6909836 TI - A psychiatric sister's ABC-14. PMID- 6909837 TI - Communicating with dying patients. PMID- 6909838 TI - Bedside or classroom? PMID- 6909839 TI - Complain at your ease. PMID- 6909840 TI - Good management makes good nursing. PMID- 6909841 TI - The monster of health: could you care more? PMID- 6909842 TI - Sickness and absenteeism survey. PMID- 6909843 TI - Nursing care study: subungual melanoma of the left big toe. PMID- 6909845 TI - Swimming aids for laryngectomees. PMID- 6909844 TI - Problems of communication in patient care. PMID- 6909846 TI - Haemodialysis-3. PMID- 6909847 TI - Communication skills: talking points. 19. You mustn't say that. PMID- 6909848 TI - Picric acid poisoning. PMID- 6909849 TI - A psychiatric sister's ABC-15. PMID- 6909850 TI - The Aberdeen Formula psychiatric X-factor -- fact or fiction? PMID- 6909851 TI - The psychiatric nurse in general practice. PMID- 6909852 TI - Spotlight on children: a disabled mother. PMID- 6909853 TI - Pressure sores. 6. Physical methods. PMID- 6909854 TI - Spotlight on children: the hidden handicap. PMID- 6909855 TI - Spotlight on children: a clicky hip. PMID- 6909856 TI - Spotlight on children: the mentally handicapped and the family. PMID- 6909857 TI - Spotlight on children: early screening for hearing impairment. PMID- 6909858 TI - Nursing care in the ICU: communication skills. PMID- 6909860 TI - The nursing process in action - I. The quiet revolution: introduction of the nursing process in a region. PMID- 6909859 TI - Theorists get it wrong. PMID- 6909862 TI - Statistics for nurse managers-1. Why should they understand them? PMID- 6909861 TI - Nursing care study: a baby with necrotising enterocolitis. PMID- 6909865 TI - Organising a library for the school of nursing. 1. Basic functions. PMID- 6909863 TI - A psychiatric sister's ABC-16. PMID- 6909864 TI - Communication skills: talking points. 20. I've just got a little jab for you. PMID- 6909866 TI - Symposium on emergency nursing. Foreword. PMID- 6909867 TI - Symposium on child abuse and neglect. Foreword. PMID- 6909868 TI - Child abuse: recognition and reporting by health professionals. AB - Nurses who are involved in child abuse and neglect have three major areas of concern: the child, the parent or caretaker, and their personal feelings. In terms of the child, the nurse needs to know the physical and behavioral indicators of abuse and neglect in order to make objective assessments. Indicators may be mild or severe, and usually occur in a pattern or in combination. The abused child may evoke sympathy in the nurse to an extent that may be detrimental to the resolution of a family problem. In terms of the parent, the nurse needs to determine the presence or absence of mental pathology and to recognize the good intent of the majority of abusive and neglectful parents. In dealing with parents, the nurse must always be honest, nonjudgmental, and supportive. Discussion of the report offers the best opportunity for providing support. Personal feelings are the greatest obstacle to the successful management of child abuse and neglect. Nurses must recognize their feelings regarding "proper" discipline and their fear of "getting involved." The feeling that "it's none of my business" must be overcome, and positive attitudes toward the parents and reporting must be promoted. Recognition of legal and moral responsibilities must take precedence over personal feelings. Through professional involvement, nurses can contribute to the primary prevention of child abuse and neglect. PMID- 6909869 TI - Dealing with feelings: who is the victim? AB - The nurse is an essential member of the child abuse team. Provision of care to identified abusive families requires intense, long-term intervention. Without a clear understanding of the emotions being experienced by family unit and the professionals involved in their care, progress will be limited. It is the responsibility of the nurse to identify and work through feelings, to recognize factors contributing to the family's behavior, and to provide quality care. Anger, shock, or pity inhibit effective treatment. The nurse is not expected to feel positively about injury of a child, but is required to take the steps necessary to understand the dynamics of abuse. PMID- 6909870 TI - Care of the hospitalized abused child and family. A framework for nursing intervention. PMID- 6909871 TI - Triage systems. AB - Triage is the process by which patients are assessed upon their arrival at a health care facility to determine the urgency of their problem and to determine the appropriate health care resource. Of the five major types of triage, advanced triage is the most comprehensive system. It includes initial assessment, initiation of diagnostic procedures, appropriate physical examination, documentation, and a referral system. Implementation of a triage system should include didactic components, a clinical trial, written examinations, and documented certification. PMID- 6909872 TI - Legal aspects of child abuse: guidelines for the nurse. AB - Legislation provides certain mandates for the identification and treatment of child abuse and neglect. State intervention on behalf of the child occurs at the onset of suspected abuse or neglect. Court involvement may be necessary to ensure the protection of children through court-ordered provision of services to families. The implementation of legal mandates requires a multidisciplinary effort, so that nurses who work with children and families need to know the child abuse legislation of the state in which they practice. Because of their professional skills, nurses are in a vital position to identify and assist vulnerable children and families. Through effective reporting, record-keeping, and an understanding of the uses and benefits of court intervention, nurses can effect a positive impact upon the legal system in behalf of abused children and their families. PMID- 6909873 TI - A multidisciplinary approach to child abuse. AB - The multidisciplinary approach has been utilized extensively by health care professions working with child abuse and neglect families. The multidisciplinary approach has allowed nurses, physicians, social workers, and mental health workers to collaborate in resolving complex problems. Multidisciplinary teams have taken many forms, depending on the demonstrated needs of the clinical setting. The many functions of the team may be summarized as: information sharing, decision-making, support, and planning. Additional advantages include role clarification and many benefits for patients and families. Despite a number of well-recognized disadvantages, the multidisciplinary approach appears to have become well established in the child abuse field. Its application to other health care problems may lead to further collaboration among members of the health care professions. PMID- 6909874 TI - Child abuse: the nurse and prevention. AB - As professional practitioners, nurses can promote prevention by becoming knowledgeable about all aspects of the phenomenon of child abuse, by carefully scrutinizing their own beliefs and values, and by monitoring their own behavior. By careful use of the problem-solving approach in their practices they can effectively intervene in potentially problematic situations. As citizens who have more complete and accurate information than their lay counterparts, they can be vital resources. They can support movements and legislation that seek to establish methods for preventing child neglect and abuse, and where neither movements nor legislation exists, they can promote both. Finally, nurses can promote and participate in relevant research that will continue to identify causes and seek solutions. PMID- 6909875 TI - Sexual abuse of children: case finding and clinical assessment. PMID- 6909876 TI - Evaluation of acute chest pain. PMID- 6909877 TI - Clinical assessment and priority-setting. PMID- 6909878 TI - Management of cardiopulmonary arrest. PMID- 6909879 TI - Emergency management of the unconscious patient. PMID- 6909881 TI - Psychiatric emergencies and crisis intervention. PMID- 6909880 TI - Adult respiratory medical emergencies. AB - Respiratory emergencies are a challenge, both to the patient's life and to the nurse who must deal with the emergency. Regardless of the initiating event, the patient must be assessed and treatment instituted rapidly. Clearing of the airway and breathing are the first two considerations for action in the emergency department's protocol, and in many cases it will be the sole responsibility of the nurse to facilitate these essential functions. PMID- 6909882 TI - The role of the nurse in the care of sexual assault victims. AB - In this article, a unique and comprehensive role has been described for the nurse who functions within the context of a rape counseling team. Nurses can assume a variety of nontraditional roles in facilitating the recovery of sexual assault victims. They can function as crisis intervention counselors, victim advocates with regard to law enforcement and medical personnel, as well as educators in relation to both the victim's significant other and to legal, medical, mental health personnel with whom the victim may interact. The nurse who responds to the victim in a holistic manner, fulfilling a number of nontraditional roles, can promote the victim's smooth navigation of systems involved with her care. In so doing, the nurse provides continuity of care and facilitates the victim's recovery from the trauma of sexual assault by simplifying the process of treatment. PMID- 6909883 TI - The "Angel of Death": the anatomy of 1980's major news story about nursing. PMID- 6909884 TI - Nursing administration in crisis. PMID- 6909885 TI - Physiological response to stress: a nursing concern. PMID- 6909886 TI - Reminiscence in old age. PMID- 6909888 TI - How to understand and communicate with a person in sorrow. PMID- 6909887 TI - Moral education for nursing. PMID- 6909889 TI - On research and the professionalization of nursing. PMID- 6909891 TI - Nursing: thoughts on nursing service and identification of the service offered. PMID- 6909890 TI - Nursing in transition: issues and challenges. PMID- 6909893 TI - Resolutions adopted by World Conference of the United Nations Decade for Women: equality, development and peace. PMID- 6909892 TI - Choice of profession, role performance and future orientation--a sociological study of nurses. PMID- 6909894 TI - I know how you feel... PMID- 6909895 TI - Prevention. A tense situation. PMID- 6909896 TI - Psychiatry. 5. Thought control. PMID- 6909897 TI - District nurse training. 3. A matter of practice. PMID- 6909898 TI - Antenatal care in North America. Full of Western promise. PMID- 6909899 TI - Nursing overseas. Medical safari. PMID- 6909900 TI - Alcoholism, who are the experts? PMID- 6909901 TI - Bereavement. A 'hush-hush' subject. PMID- 6909902 TI - Intraocular foreign bodies. An eye for treatment. PMID- 6909903 TI - Brain tumour. Where there's hope, there's life. PMID- 6909905 TI - The patient's advocate. PMID- 6909904 TI - Suitable to nurse? PMID- 6909906 TI - The games people play. PMID- 6909907 TI - Yoga and pregnancy. Unbending thoughts. PMID- 6909908 TI - Cholelithiasis. PMID- 6909909 TI - A loving thing to do. PMID- 6909910 TI - Is your brain really necessary? PMID- 6909911 TI - Nurse responsibilities: easy does it! PMID- 6909912 TI - Circadian rhythms: clocking in. PMID- 6909914 TI - Ectopic pregnancy: the pain in Spain. PMID- 6909913 TI - Veterinary diseases and man: psittacosis. PMID- 6909915 TI - Foreign report: for a few dollars more. PMID- 6909916 TI - The official secrets act? PMID- 6909917 TI - Waking patients up. Rise and shine? PMID- 6909919 TI - Education and the RMN. Room for change? PMID- 6909918 TI - Designed for children. PMID- 6909920 TI - Olfaction. Not to be sniffed at. PMID- 6909921 TI - Paranoid schizophrenia. A serpent which licked my eyes... PMID- 6909922 TI - When the masquerade is over... PMID- 6909924 TI - The publishing process. Who better to serve the nurse? PMID- 6909923 TI - The publishing process. PMID- 6909925 TI - The publishing process. Getting it together. PMID- 6909928 TI - The publishing process. When no news is bad news. PMID- 6909927 TI - The publishing process. The forgotten few. PMID- 6909926 TI - The publishing process. Postman's knock... PMID- 6909929 TI - The publishing process. Everything (else) you wanted to know... PMID- 6909930 TI - Caring across the Atlantic. PMID- 6909931 TI - Supplement. Nursing education. PMID- 6909932 TI - Nurse education. Not so quite on the central council front.... Interview by Mark Allen. PMID- 6909935 TI - Learning to teach. PMID- 6909933 TI - Will they shoot the director of education at dawn?. Interview by Tamara Ross. PMID- 6909934 TI - Training for reality. PMID- 6909936 TI - A dream come true? PMID- 6909937 TI - Nurse education. Continuous assessment. PMID- 6909938 TI - Nurse education: holism: a philosophy of life. PMID- 6909939 TI - Nurse education: night duty and the nurse. PMID- 6909940 TI - Nurse education: primary degree courses. PMID- 6909941 TI - Let's find time to talk. PMID- 6909942 TI - Nursing practice. Knowledge is everything. PMID- 6909944 TI - Acute bronchitis. PMID- 6909943 TI - Man's best friend? PMID- 6909945 TI - Staff development: groomed for management. PMID- 6909946 TI - Hydatid disease. A vicious cycle. PMID- 6909947 TI - Teratoma. Putting two and two together. PMID- 6909949 TI - Accidents in childhood. PMID- 6909948 TI - The million dollar question. TUC affiliation for nurses. PMID- 6909950 TI - Accidents in childhood: careful-don't touch! PMID- 6909951 TI - Accidents in childhood: a childproof environment. PMID- 6909954 TI - By appointment only? PMID- 6909953 TI - Who are you kidding? PMID- 6909952 TI - Accidents in childhood: growing to independence. PMID- 6909955 TI - Deafness: breaking through the sound barrier. PMID- 6909956 TI - Prevention: the deadly crab. PMID- 6909957 TI - Third World health: building on what they have. PMID- 6909958 TI - Clinical nurse specialists: something special. PMID- 6909959 TI - Problem children: the non-conformists. PMID- 6909960 TI - Nursing care study.--Secondary carcinoma: fighting a losing battle. PMID- 6909961 TI - Maintaining professional purity? PMID- 6909962 TI - Nursing racial equality. PMID- 6909963 TI - Portage system: programmed for success. PMID- 6909964 TI - Voluntary nursing: helping hands. PMID- 6909965 TI - Alcoholism: on the rocks. PMID- 6909966 TI - Let's look at a problem: acute nephritis. PMID- 6909967 TI - Recovering from illness: looking down the road to recovery. PMID- 6909968 TI - Immunosuppression: 'foreign bodies' in the womb. PMID- 6909969 TI - Research report: a light in the tunnel? PMID- 6909970 TI - Nursing care study. Manic-depressive psychosis: 'I can't get it out of my head.'. PMID- 6909971 TI - If you've named one you've named them all! PMID- 6909972 TI - Why was Sister Jennings put on the carpet? PMID- 6909973 TI - What's your line? PMID- 6909974 TI - Not waving, but drowning. PMID- 6909975 TI - Coping with death: a time of stress. PMID- 6909976 TI - Meningitis: Christopher--alive but dead. PMID- 6909977 TI - Community nursing. Group therapy: reducing the risks together. PMID- 6909978 TI - Plastic surgery: hard to swallow. PMID- 6909979 TI - Felty's syndrome: a triad of problems. PMID- 6909980 TI - Veterinary diseases and man: brucellosis. PMID- 6909981 TI - Are you the sex lady, Miss? PMID- 6909982 TI - Law and the nurse. 2. A duty to care. PMID- 6909983 TI - Let's look at a problem: abdominal hernia. PMID- 6909984 TI - Capacity of schools of nursing: a model for the future. PMID- 6909985 TI - District nurse training. 1. How can we manage without it? PMID- 6909986 TI - Nursing care study. Cerebral palsy: a case for careful handling. PMID- 6909987 TI - The new face of Normansfield. PMID- 6909988 TI - Beanz meanz laughs. PMID- 6909990 TI - COHSE conference? A cosy meeting? PMID- 6909989 TI - Albert Spanswick: a man of his word. Interview by Mark Allen. PMID- 6909991 TI - Law and the nurse. 3. What will happen to Sister Duncan? PMID- 6909992 TI - Nursing in tomorrow's world. 1. Beam me up, nurse! PMID- 6909993 TI - Nursing auxiliaries: like the 'wee wifie' next door? PMID- 6909994 TI - District nurse training. 2. The price of progress. PMID- 6909995 TI - Psychiatry: wind of change. PMID- 6909996 TI - Mental handicap: standing on the outside. PMID- 6909997 TI - Patrick splint: towards immediate mobility. PMID- 6909999 TI - Nursing care study: psychiatry. Lydia: a lonely lady. PMID- 6910000 TI - Reaching out for the primary health care team. PMID- 6909998 TI - Forensic psychiatry: old habits die hard. PMID- 6910002 TI - Nurse practitioners in the USA: from handmaiden to health specialist? PMID- 6910001 TI - The end of term? PMID- 6910003 TI - Psychiatric nursing in the USA: that'll do nicely. PMID- 6910004 TI - Nursing in tomorrow's world. 2. A five star future. PMID- 6910006 TI - Prevention: getting the balance right. PMID- 6910005 TI - Law and the nurse. 4. The great brain death debate. PMID- 6910007 TI - Students' forum. Let's look at a problem: amputation. PMID- 6910008 TI - Wound dressing: foam - a new approach. PMID- 6910009 TI - Drug dosage and the elderly: old enough to know better. PMID- 6910011 TI - Nursing care study. Puerperal psychosis: with a lot of help from her friends. PMID- 6910010 TI - Breast cancer: time is of the essence. PMID- 6910012 TI - When is a learner not a learner? PMID- 6910013 TI - Look after your learners. PMID- 6910014 TI - Sliding down the scale. PMID- 6910015 TI - Nursing in the navy: keeping the fleet afloat. PMID- 6910017 TI - Writing a research project: let's start at a very beginning. PMID- 6910016 TI - Law and the nurse. 5. From all points of view. PMID- 6910018 TI - Informed consent: given the facts. PMID- 6910019 TI - Agoraphobia: far from the madding crowd. PMID- 6910020 TI - Nursing care study. Jaundice: putting up the barriers. PMID- 6910021 TI - Compassion, suffering, morality: ethical dilemmas in caring. PMID- 6910023 TI - Hospital responsibilities to the general public. PMID- 6910022 TI - Orders not to resuscitate: the Sharon Siebert case. PMID- 6910024 TI - [The role of nutrition in the preservation of health]. PMID- 6910025 TI - [Stress provoked by work]. PMID- 6910026 TI - [A small child's health]. PMID- 6910027 TI - [Professional improvement]. PMID- 6910028 TI - [The way nursing should be taught]. PMID- 6910029 TI - [Infant nursing]. PMID- 6910031 TI - [The visiting nurse]. PMID- 6910030 TI - [Ethical problems]. PMID- 6910032 TI - [The sanatorium at Zagorze]. PMID- 6910033 TI - [Chronic cor pulmonale]. PMID- 6910034 TI - [Endosseous dental implantation]. PMID- 6910037 TI - [Art therapy in spa therapy]. PMID- 6910036 TI - [Duties, rights and responsibilities of a nurse]. PMID- 6910035 TI - [Lassa fever]. PMID- 6910038 TI - [Principles of disinfection]. PMID- 6910039 TI - [Perfecting one's professional knowledge]. PMID- 6910041 TI - [The entrance examination]. PMID- 6910040 TI - [Advances in stomatology]. PMID- 6910042 TI - [The social theory of nursing]. PMID- 6910043 TI - [Something called a sanatarium]. PMID- 6910044 TI - [Olympic minigames]. PMID- 6910045 TI - [Breast feeding]. PMID- 6910046 TI - [The nurse in a therapeutic role]. PMID- 6910047 TI - [A nurse's workload]. PMID- 6910048 TI - [Physiological role of food components. 1]. PMID- 6910049 TI - [Worker assessment]. PMID- 6910050 TI - [Medical rehabilitation: the nurse's role]. PMID- 6910052 TI - [Current problems in rehabilitation]. PMID- 6910051 TI - [Health of the small child]. PMID- 6910053 TI - [Nursing diagnosis]. PMID- 6910054 TI - [Tetanus]. PMID- 6910055 TI - [Psychological aspects of carrying pregnancy to term]. PMID- 6910056 TI - [Postmyocardial infarct]. PMID- 6910057 TI - [Hospital in Brodnica]. PMID- 6910058 TI - [Occlusal disorders]. PMID- 6910059 TI - [Education for the caring function]. PMID- 6910060 TI - [School and professional specialization]. PMID- 6910062 TI - [Woman in Poland]. PMID- 6910061 TI - [Problems of adaptation in the profession]. PMID- 6910063 TI - [Education for the caring function. II]. PMID- 6910064 TI - [Rehabilitation in injuries to the extremities]. PMID- 6910065 TI - [Correspondence education system]. PMID- 6910066 TI - [Nursing care process]. PMID- 6910068 TI - [... Remember us, school]. PMID- 6910067 TI - [Public-spirited distinction]. PMID- 6910069 TI - [Physiological role of food components. II]. PMID- 6910070 TI - [Perinatal fetal injuries]. PMID- 6910071 TI - [Plan for organizing nursing. The department of nursing]. PMID- 6910072 TI - The law and your practice. PMID- 6910074 TI - Midwifery: outside nursing scope. Case in point: Leggett v. Tennessee Bd. of Nursing (612 S.W. 2d 476 - TENN.). PMID- 6910073 TI - Nurses and medical records: legalities. PMID- 6910075 TI - Legal case briefs for nurses. TX: bedfall: unanticipated; no liability. IN: E.R. nurse is hospital agent. PMID- 6910077 TI - Nurses and doctors interchangeable as expert witnesses. Case in point: Avert v. McCormick (271 S.E. 2d 832 - GA.). PMID- 6910078 TI - Legal case briefs for nurses. MA: still another bed rail mishap! LA: nurse anesthetist in valium error. PMID- 6910076 TI - Geriatrics: nursing assistance for elderly. Case in point: Block v. Michael Reese Hosp. & Med. Ctr. (417 N.E. 2d 724 - ILL.). PMID- 6910079 TI - Psychiatric nursing: restraint & supervision of patients. Case in point: Vattimo v. Lower Bucks Hospital (428 A 2d 765 - PA.). PMID- 6910080 TI - [Anatomy of the kidney]. PMID- 6910081 TI - [Acute polyradiculoneuritis. 1. Medical aspects]. PMID- 6910082 TI - [Acute polyradiculoneuritis. 2. Therapy and care by paramedial personnel]. PMID- 6910083 TI - [Common problems in young children. 2. Common pathology]. PMID- 6910084 TI - [Prevention of contagious diseases]. PMID- 6910085 TI - [The placebo effect: integral part of nursing care]. PMID- 6910086 TI - [Pets and mental health]. PMID- 6910087 TI - [Kidney tumors]. PMID- 6910088 TI - [Definition of a function: supervisor]. PMID- 6910089 TI - [Current aspects of tuberculous meningitis]. PMID- 6910090 TI - [State of shock]. PMID- 6910091 TI - [Occupational accidents: from care to prevention]. PMID- 6910092 TI - [Dietetics in digestive pathology: pathology of the colon]. PMID- 6910093 TI - [Paraneoplastic syndromes]. PMID- 6910094 TI - [Day of debate on the right to health]. PMID- 6910095 TI - [Prevention of ulcero-necrotizing enterocolitis of the newborn in public and private gynecological and obstetrical services]. PMID- 6910096 TI - [Echotomographie: physical principles and formation of the image]. PMID- 6910097 TI - [Technique: drainage of wounds under depression, Redon's method]. PMID- 6910098 TI - Sex Q & A. Frank answers to your most delicate patient counseling questions. PMID- 6910099 TI - Are you getting your share? PMID- 6910100 TI - Urgent priorities in severe trauma: life-threatening head and spinal injuries. PMID- 6910101 TI - Now--peritoneal dialysis for chronic patients, too. PMID- 6910102 TI - Is it an MI? PMID- 6910103 TI - 'Take with meals'...or not? Part II. PMID- 6910104 TI - Precautions to take with dextrose and hypotonic saline. PMID- 6910105 TI - Legally speaking: how to cover yourself when the MD's wrong. PMID- 6910106 TI - Sound off! Death without dignity. PMID- 6910107 TI - Sex Q & A: frank answers to your most delicate patient counseling questions. PMID- 6910108 TI - Innovative nursing for a 'worst case' wound. PMID- 6910109 TI - Warning signs to watch for in your post-MI patient. PMID- 6910111 TI - Salary survey: how inflation has chiseled away your gains. PMID- 6910110 TI - Urgent priorities in severe trauma: abdominal injuries and dangerous fractures. PMID- 6910112 TI - What to watch for with lithium. PMID- 6910113 TI - Are you cut out for terminal care? PMID- 6910114 TI - Electrolyte solutions: monitor, monitor, monitor! PMID- 6910115 TI - Do-it-yourself dialysis. PMID- 6910116 TI - Legally speaking: 1001 ways to land in court. PMID- 6910117 TI - Advice of counsel. Your civil rights go only so far. PMID- 6910118 TI - Sound off! Why fight floating? PMID- 6910119 TI - Does QAP work? PMID- 6910120 TI - Then I had a baby. PMID- 6910121 TI - The real cause of our discontent. PMID- 6910123 TI - Safety to practice: what's in it for you? PMID- 6910122 TI - RNABC discipline process: is nursing care safe? PMID- 6910124 TI - [The Hospital Federation of France in defense of public hospital]. PMID- 6910125 TI - [Nurse in mountain country]. PMID- 6910126 TI - [Progress in stoma therapy: the Combihesive system]. PMID- 6910127 TI - [The habits of young children]. PMID- 6910128 TI - [Disposable drawsheets... protected beds]. PMID- 6910129 TI - [The nurse's body]. PMID- 6910130 TI - [Those who monitor the French pharmacies]. PMID- 6910131 TI - [Management of bites]. PMID- 6910132 TI - [Care of the aged]. PMID- 6910133 TI - [The bedpan, so ill-liked]. PMID- 6910134 TI - [The important thing is to talk about it!]. PMID- 6910135 TI - [Softening of the brain]. PMID- 6910136 TI - [Hemiplegia]. PMID- 6910138 TI - [Abnormal movements]. PMID- 6910137 TI - [Cerebro-vascular hemorrhagic accidents]. PMID- 6910139 TI - [L. Dopa]. PMID- 6910140 TI - [Helping a motor-sensory handicapped patient]. PMID- 6910141 TI - [A case of Parkinson's disease]. PMID- 6910142 TI - [Human sciences and nursing care]. PMID- 6910143 TI - [New program...initial assessments]. PMID- 6910144 TI - [Saltwater and freshwater products]. PMID- 6910146 TI - [Mitral valve stenosis]. PMID- 6910145 TI - [Acquired mitral valve insufficiency]. PMID- 6910147 TI - [Aortic insufficiency in adults]. PMID- 6910148 TI - [Congenital or acquired, never to be neglected]. PMID- 6910150 TI - [Acquired diseases of the tricuspid aperture]. PMID- 6910149 TI - [Acquired aortic stenosis in adults]. PMID- 6910151 TI - [Polyvalvulopathies]. PMID- 6910152 TI - [Congenital heart valve diseases, pulmonary and aortic stenosis]. PMID- 6910153 TI - [Anesthesia and per-operative resuscitation]. PMID- 6910154 TI - [Final examination of module I. Nursing school D.E. of the Department of Paris]. PMID- 6910155 TI - [Legislation of recruitment and promotion conditions: allied health personnel and nursing personnel]. PMID- 6910157 TI - [Pulmonary valve stenosis]. PMID- 6910156 TI - [Congenital aortic valve stenosis]. PMID- 6910158 TI - [Valvular surgery]. PMID- 6910159 TI - [Complex surgery, careful monitoring]. PMID- 6910160 TI - [Calciparin]. PMID- 6910161 TI - [Bloodletting]. PMID- 6910162 TI - [Percutaneous catheterization]. PMID- 6910163 TI - [Mrs B...hospitalized for catheterization]. PMID- 6910164 TI - [Medical treatment of valvulopathies]. PMID- 6910165 TI - [Food and beverage hygiene: standards of freshness for fish. Bread]. PMID- 6910166 TI - [Recruitment and promotion of administrative and supervisory personnel in educational centers]. PMID- 6910167 TI - [Legislation: sterilization with ethylene oxyde]. PMID- 6910168 TI - [Surgery of valvulopathies]. PMID- 6910169 TI - [Determination of visual acuity in the young child]. PMID- 6910170 TI - [Measurement of visual acuity in the adult. Precautions to be taken]. PMID- 6910171 TI - [How to determine ocular tension?]. PMID- 6910173 TI - [Everyday tests in a specialized pathology]. PMID- 6910174 TI - [Pre- and post-operative care of retinal detachment]. PMID- 6910172 TI - [Pre- and post-operative care of glaucoma]. PMID- 6910175 TI - [A case of acute glaucoma]. PMID- 6910176 TI - [Physiology of the eye]. PMID- 6910177 TI - [A case of corneal ulcer]. PMID- 6910179 TI - [Timoptol]. PMID- 6910180 TI - [Lenses]. PMID- 6910178 TI - [Eye washes]. PMID- 6910181 TI - [Lasers in ophthalmology]. PMID- 6910182 TI - [Nanterre 1980--two theories]. PMID- 6910183 TI - [Per-operative monitoring]. PMID- 6910184 TI - [Per-operative resuscitation]. PMID- 6910185 TI - [Father, birth and child]. PMID- 6910186 TI - [Place of the mother during her stay in a maternity ward]. PMID- 6910187 TI - [Revealing a genetic disease to the parents of a stricken child]. PMID- 6910189 TI - [Coordinated case finding of phenylketonuria and hypothyroidism in France]. PMID- 6910188 TI - [The health care team at birth: don't substitute for the parents]. PMID- 6910190 TI - [What kind of parent-health care professional communication in neonatal resuscitation?]. PMID- 6910191 TI - [Introduction: parent-child-nurse relations in maternity care]. PMID- 6910192 TI - [Psychodynamics of parents of premature infants and of the health care team]. PMID- 6910193 TI - [Basic nursing care on the maternity ward]. PMID- 6910194 TI - [Mother-child relations]. PMID- 6910195 TI - [Advice upon leaving the maternity ward]. PMID- 6910197 TI - [Health care records]. PMID- 6910196 TI - [Responsibility of auxiliary medical personnel employed in private hospitals]. PMID- 6910198 TI - [Microbiological criteria for certain animal foods or foods of animal origin]. PMID- 6910200 TI - [46th congress of the French National Association of State Certified Nurses and Nursing Students. Place of the nurse in the economic and social order. Towards what professional project?]. PMID- 6910199 TI - [Per-operative complications]. PMID- 6910201 TI - [Abdominal parietal emergencies]. PMID- 6910202 TI - [Hernias]. PMID- 6910203 TI - [Dakins' solution]. PMID- 6910204 TI - [Food and beverage hygiene. Drinking water and ice--dietary foods]. PMID- 6910205 TI - [An example to follow: educational action for health in the framework of the fair exhibit of Limoges]. PMID- 6910207 TI - [Nurses. Report of the general inspection of social affairs]. PMID- 6910206 TI - [The ambulatory care nurse and cardio-vascular diseases in an occupational setting]. PMID- 6910208 TI - [Eating behavior and obesity]. PMID- 6910209 TI - [Obesity: a complex phenomenon]. PMID- 6910210 TI - [Risks and complications of obesity]. PMID- 6910212 TI - [Practical methods for studying obesity]. PMID- 6910213 TI - [Epidemiology of obesity]. PMID- 6910211 TI - [Hormonal disturbances and obesity in the child]. PMID- 6910214 TI - [Practical dietetics for obesity]. PMID- 6910216 TI - [Dietary and drug abuse during reducing therapy]. PMID- 6910215 TI - [Treatment of obesity in terms of a cure. Principles of dietetics and adjuvants]. PMID- 6910217 TI - [Ponderal Retard]. PMID- 6910218 TI - [Treatment of obesity in metabolic units: a double polarity]. PMID- 6910219 TI - [The nurse and migrants]. PMID- 6910220 TI - [Obesity: definition, diagnosis procedures and classification]. PMID- 6910221 TI - [Study of water-electrolyte disorders]. PMID- 6910222 TI - [Hydration disorders]. PMID- 6910223 TI - [Hyponatremia]. PMID- 6910224 TI - [Homeostasis: a very complex equilibrium that can be disturbed by many causes]. PMID- 6910225 TI - [Hypokalemias and hyperkalemias]. PMID- 6910226 TI - [Lasilix]. PMID- 6910227 TI - [Acid-base equilibrium: control--studies]. PMID- 6910228 TI - [Water-electrolyte composition of the body]. PMID- 6910230 TI - [Water-electrolyte and acid-base disorders in terminal chronic renal insufficiency. Their treatment by peritoneal dialysis]. PMID- 6910229 TI - [Acid-base disorders]. PMID- 6910232 TI - [Renal control of water-electrolyte balance]. PMID- 6910231 TI - [Pediatric needs in allergy. Requirements and reality: practical organization of a day hospital]. PMID- 6910233 TI - [Vascular aches of the face]. PMID- 6910235 TI - [Variability and complexity of pain]. PMID- 6910234 TI - [Trigeminal neuralgia]. PMID- 6910236 TI - [Acute abdominal pain]. PMID- 6910237 TI - [Nephrotic colic]. PMID- 6910238 TI - [Pain and the nervous system]. PMID- 6910239 TI - [Surgical treatment of pain]. PMID- 6910240 TI - [Pain]. PMID- 6910241 TI - [Painful situations suffered at the hospital]. PMID- 6910243 TI - [Informative labeling--qualified organizations]. PMID- 6910242 TI - [Nursing interventions in relation to pain]. PMID- 6910244 TI - [Migraine]. PMID- 6910245 TI - [Deafness and associated disorders]. PMID- 6910247 TI - [Different treatments for hearing disorders]. PMID- 6910246 TI - [Functional exploration of hearing]. PMID- 6910249 TI - [One of the most serious afflictions that can hurt man]. PMID- 6910248 TI - [Two concrete cases of deafness]. PMID- 6910250 TI - [Legislation for the deaf]. PMID- 6910251 TI - [Role of the nurse in hospital hygiene]. PMID- 6910252 TI - [Anatomo-physiologic bases of hearing]. PMID- 6910253 TI - [Hearing disorders]. PMID- 6910254 TI - [Anaerobic infections]. PMID- 6910255 TI - [Antibiotic intolerance with the exception of cutaneous manifestations]. PMID- 6910256 TI - [From antibiotics to "nursing audit"]. PMID- 6910257 TI - [Classification of antibiotics and antibacterial agents (excluding antitubercular agents)]. PMID- 6910258 TI - [Role of the laboratory in antibiotic therapy]. PMID- 6910259 TI - [Meningitis]. PMID- 6910260 TI - [A case of meningococcal meningitis]. PMID- 6910261 TI - [Antibiotics and health care economics]. PMID- 6910262 TI - [The "nursing audit" or evaluation of nursing care at the American Hospital in Paris]. PMID- 6910264 TI - The use of transactional analysis in patient teaching. PMID- 6910263 TI - Law for the nurse supervisor: rights of mental patients. PMID- 6910265 TI - Sabotage in nursing. PMID- 6910266 TI - Toward optimal patient care: the nursing conference. PMID- 6910267 TI - The consumer's perception of nursing care. PMID- 6910268 TI - Measuring quality of patient care: a computerized approach. PMID- 6910269 TI - Quality assurance beyond the bloodbank. PMID- 6910270 TI - The art and science of supervision. On your toes! PMID- 6910271 TI - Every which way but up... PMID- 6910272 TI - Recent developments in consent to treatment--Part 1. PMID- 6910273 TI - Supervisory nurses & continuing education. PMID- 6910274 TI - Patient power & powerlessness. PMID- 6910275 TI - Preceptors. A resource for new nurses. PMID- 6910278 TI - Nursing care in a technological age. PMID- 6910277 TI - A systematic approach to developing a dress code. PMID- 6910276 TI - Extending the role of the coronary care nurse. PMID- 6910281 TI - Nursing's token leaders. PMID- 6910279 TI - The role of nursing education in critical care. PMID- 6910280 TI - The art and science of supervision. Mind and heart. PMID- 6910282 TI - Are you using the wrong yardstick? The art & science of supervision. PMID- 6910283 TI - The nursing shortage: this time traditional responses won't work. PMID- 6910284 TI - Ethical decisions in daily practice. PMID- 6910285 TI - The clinical coordinator in a changing system. PMID- 6910286 TI - Data presentation in infection control. PMID- 6910287 TI - The dynamics of a strike. PMID- 6910288 TI - Does the career woman face infertility? PMID- 6910289 TI - Nurse power--projecting self & ideas. PMID- 6910290 TI - The jawbone of an ass. PMID- 6910291 TI - Law for the nurse supervisor. Recent developments in consent to treatment--Part II. PMID- 6910292 TI - [Nurse, keep your finger on the pulse!]. PMID- 6910294 TI - [Patient groups - who are they? What do they want?]. PMID- 6910293 TI - [Nursing care of patients with brain damage - behavior therapy approach]. PMID- 6910295 TI - [The aging mentally retarded patient in the institution]. PMID- 6910296 TI - [Revealing symptoms in bacterial infections]. PMID- 6910297 TI - [Radical psychiatry and emancipating therapy]. PMID- 6910298 TI - [Compulsory training?]. PMID- 6910299 TI - [The significance of Dwyer's spondylodesis method in the treatment of severe spinal deformities]. PMID- 6910300 TI - [Suicidal behavior of psychiatric patients]. PMID- 6910301 TI - [The bad-news communication]. PMID- 6910303 TI - [The significance of interpersonal relations between patients]. PMID- 6910302 TI - [FONA (errors, incidents and near accidents) committees in hospitals]. PMID- 6910304 TI - [The road peculiar to professional nursing associations. Professional activities in the Christian professional association]. PMID- 6910305 TI - [Competencies and qualifications of the nursing instructor in the intermediate professional education]. PMID- 6910306 TI - [The Nursing Advisory Council of the Netherland Heart Foundation]. PMID- 6910308 TI - [Work management in the nursing department - how often does it occur and what does it involve?]. PMID- 6910307 TI - [Tampon disease]. PMID- 6910309 TI - [The new basic nursing education: what is the current status?]. PMID- 6910310 TI - [Developments concerning the intermediate professional nursing education]. PMID- 6910311 TI - [Regression therapy]. PMID- 6910312 TI - [Is care for the mentally retarded health care?]. PMID- 6910313 TI - [The C. O. C. M. A. (Central Educational Course for Intermediate Diploma) Nursing Instructors' Education in Leusden]. PMID- 6910314 TI - [Het Beterschap, that's you yourself]. PMID- 6910315 TI - Bacteriologic competence of the twin peel suture package. PMID- 6910316 TI - Jane Thelen: OR nurse. PMID- 6910317 TI - Test your knowledge: the process of change. PMID- 6910318 TI - Innovative scheduling in the OR: you bet!. Interview by Carter Jarrell. PMID- 6910319 TI - Exercise and the maintenance of health. PMID- 6910320 TI - Fitness evaluation. PMID- 6910321 TI - Creative movement and health. PMID- 6910322 TI - Exercise before, during, and after pregnancy. PMID- 6910324 TI - Exercise-induced injuries. PMID- 6910323 TI - Running: immunization against the diseases of hypokinesis. PMID- 6910325 TI - The effects of controlled exercise on the client with coronary artery disease. PMID- 6910326 TI - Running therapy for the depressed client. PMID- 6910327 TI - Exercise therapy for the patient with pulmonary dysfunction. PMID- 6910329 TI - The who, what, when, why and how of professional negotiations for nurses. PMID- 6910328 TI - The prevention of hyaline membrane disease (HMD) in the preterm fetal lamb through the static inflation of the lungs: the conditioning of the fetal lungs. AB - Preterm fetal lambs of a gestational are highly susceptible to hyaline membrane disease were placed on apneic oxygenation while keeping the umbilical circulation intact and still connected to the mother ewe for the removal of metabolically produced CO2. After 4-6 hrs the total lung compliance and the chest x-ray films had markedly improved, allowing normal pulmonary ventilation with a mechanical ventilator. Fetuses older than 135 days gestation were later extubated and allowed to breathe room air unassisted. Fetuses 134 days gestation and younger were kept on mechanical ventilation. None of the animals so treated developed hyaline membrane disease. We believe pulmonary conditioning is an important tool in the prevention and the treatment of hyaline membrane disease. In this animal model we have shown that hyaline membrane disease is a preventable and curable disease. PMID- 6910330 TI - Challenge at the crossroads in nursing. PMID- 6910331 TI - Nursing now. PMID- 6910332 TI - A large outbreak of infections caused by a strain of Staphylococcus aureus resistant of oxacillin and aminoglycosides. AB - An extensive outbreak of nosocomial infections caused by oxacillin- and aminoglycoside-resistant Staphylococcus aureus (OARSA) occurred over a 16 month period. A total of 349 isolates of OARSA were obtained from 174 patients. Colonization with OARSA was found in 92 patients. There was 120 infections in 82 patients; 50 were surgical wound infections, 13 were nonsurgical wound infections, six were pneumonias, 15 were urinary tract infections, 12 were intravenous site infections, and there were 19 episodes of bacteremia (seven transient, 12 persistent). In patients with persistent bacteremia, the mortality rate was 33 percent. In patients treated for persistent bacteremia with vancomycin, the survival rate was 80 percent. Infections were highly associated with the surgical intensive care unit, and 90 percent of the isolates of OARSA tested had the same phage-type. Elderly patients with significant underlying disease, a history of previous surgery or of prior antimicrobial therapy appeared to be at increased risk for OARSA infections. OARSA were resistant to multiple antibiotics besides oxacillin, but all isolates were sensitive to vancomycin and rifampin. Three surgical intensive care unit nurses were found to be nasal carriers of OARSA, and one nurse had dermatitis of both hands colonized with OARSA. Following the removal of these nurses from the surgical intensive care unit and the institution of strict infection control measures, the number of OARSA infections and colonizations decreased to less than one per month. OARSA produces serious nosocomial disease, and epidemiologic intervention was effective in controlling this outbreak. PMID- 6910333 TI - Status report. PMID- 6910334 TI - Heat and heat-related illnesses. PMID- 6910335 TI - Antidepressants: old drugs, new uses. PMID- 6910336 TI - Psychotropic drugs: lithium. PMID- 6910337 TI - Using computers in newborn intensive care settings. PMID- 6910338 TI - An eclectic approach to practice. PMID- 6910339 TI - Multiple Myeloma. PMID- 6910340 TI - "That's not the way we do things around here". PMID- 6910341 TI - Coping with a leg amputation. PMID- 6910342 TI - Handling depression through positive reinforcement. PMID- 6910344 TI - Sunset laws. PMID- 6910343 TI - Of pillows and pineapple juice. PMID- 6910345 TI - Nurse practitioner in a VNA. PMID- 6910346 TI - An obligation to treat vs. a right to refuse. PMID- 6910347 TI - School nursing deserves an 'A+', says Juan Robles, R.N. PMID- 6910348 TI - Photoreceptor outer segment and retinal pigment epithelium in vitamin E deficient rats. An electron microscopic and electron histochemical study. AB - The photoreceptor outer segments and retinal pigment epithelium of vitamin E deficient rats were examined by electron microscope using electron histochemical techniques. In rats fed a vitamin E deficient diet for more than 6 months starting 20 days after birth, the photoreceptor outer segment showed vesiculation of the discs near the apical portion of the retinal pigment epithelium. In the retinal pigment epithelium, secondary lysosomes were increased in number. Reaction products of acid phosphatase activity were located in secondary lysosomes in the retinal pigment epithelium and on the disc membranes of the photoreceptor outer segment. These alterations became more prominent with the duration of vitamin E deficiency. It was assumed that the disc degeneration of the photoreceptor outer segment might be due to enhanced activity of lysosomal enzymes in the retinal pigment epithelium and the effect of released lysomal enzymes on the photoreceptor outer segment. PMID- 6910349 TI - Borna disease virus-induced retinouveitis treated with immunosuppressive drugs. AB - Borna disease occurs naturally in horses and sheep and causes an encephalomyelitis which is fatal. Little is known about the etiologic agent. There is evidence, however, that this neutrotropic virus belongs to the conventional enveloped RNA viruses. Experimentally infected rabbits exhibited a highly reproducible multifocal retinochoroidopathy. Clinical, histologic, as well as virologic results suggested that immunologic events gave rise to the characteristic clinical, histologic, as well as virologic results suggested that immunologic events gave rise to the characteristic clinical expression of the disease. To investigate possible immunpathologic factors, infected rabbits were treated with immunosuppressive drugs. As compared with controls three outstanding features were observed in the treated group: (1) The time interval between infection and the occurrence of inflammatory ocular foci was considerably prolonged; (2) confluency of retinal lesions was not noted in the early course of the disease; and (3) a lack of ocular lesions or a nonprogression over several days, never observed in controls, occurred in a small percentage of treated animals. These observations indicate that the clinical course of virus-induced inflammatory lesions of the retina and choroid can be changed by treatment with immunosuppressive drugs. It can be assumed that the appearance of the individual fundus lesion depends on the immuno-logic status of the infected host. PMID- 6910350 TI - The electric consensual response of the non-stimulated eye in normal subjects and patients with optic atrophy. PMID- 6910351 TI - The cardiac involvement in chronic progressive external ophthalmoplegia: consideration on the Kearns-Sayre syndrome. AB - The report describes a case of Kearns syndrome in which cardiac involvement occurred more than 15 years after the appearance of the myopathic disorder. The surface electrocardiogram showed a left axis deviation and Q-waves in D3 and aVF leads, and appeared against a background of general systemic worsening of the condition of the muscular system. In the eye, despite a slightly increased salt and-pepper macular pigmentary disturbance, retinal fluorescein angiography did not show significant differences in comparison with previous examinations. Some observations are made on the possible evolution of the Kearns syndrome. PMID- 6910352 TI - Incidence of epibulbar tumors in lesotho. AB - A series of 18 epibulbar tumors are reported from Lesotho, a nontropical African country. The etiologic risk factors in epibulbar tumors are evaluated in termas of the environmental conditions present in Lesotho. The pathogenesis of epibulbar tumors is discussed in terms of histological progression from benign to malignant lesions following prolonged exposure to presumed etiologic risk factors. PMID- 6910353 TI - [Barraquer-silk (8 x 0) and polyglactin 910 (8 x 0) in corneo-scleral incisions of rabbit eyes. A histological study]. AB - Barraquer-silk (8 x 0) and Polyglactin 910 (8 x 0) were histologically examined in corneo-scleral incisions of rabbit eyes. Wound healing using both suture materials was complete after two weeks, as observed by light microscopy. Barraquer-silk excited more cellular reaction than Polyglactin 910. Absorption of Polyglactin 910 suture began 18 days after surgery whilst Barraquer-silk did not begin to absorb until 42 days had passed. PMID- 6910354 TI - Octopus programs SAPRO and F. Two new principles for the analysis of the visual field. AB - The automatic Octopus perimeter has a large software development potential. An important property of the Octopus programs developed to date is their ability to distinguish between pathological and normal behaviour. At the moment, program development is concentrating upon programs in which criteria of normality are used as feed-back parameters during the examination itself, and thus guide the visual field analysis. This property permits the algorithm to undertake a precise spatial analysis of disturbed visual field areas, without wasting time on a detailed analysis of normal areas. The efficiency of a visual field examination program is thereby substantially increased (SAPRO* program). Using the F-program series, individual (as opposed to fixed) stimuli configurations can be realised, which may represent a better fit to a particular problem. The principles of two other programs, SARGON and DELTA, have been described before (Fankhauser and Jenni 1981). PMID- 6910355 TI - [Experimental and clinical examinations of the effect of cryosurgery of intraocular pressure]. AB - Diathermy and cryosurgery have different effects on living tissue. Cell membranes are ruptured by cryosurgery, but the proteins are less affected than by diathermy. A short review of experimental cyclocryosurgery and the clinical results are presented. Data from the literature as well as evaluation of patients confirm that, as yet, the results are not satisfactory. The sequelae of freezing are very different in slow-and fast-freezing procedures. Therefore, the results in rabbits treated with a cryosurgical unit used for retinal detachment surgery (Amoils, -80 degrees C) were compared with the results using a cryoprobe cooled with liquid nitrogen (-180 degrees C). A permanent reduction in intraocular pressure was not achieved using cyclocryotherapy applied with the equipment used for detachment surgery (-80 degrees C). Repeated cryosurgery of this type did not result in a permanent pressure reduction. Histopathology demonstrated that the ciliary epithelium had regenerated and prolongation of the cyclocryotherapy applications did not result in a permanent intraocular pressure reduction. Lens opacities occurred in all rabbits of this series. Application of cryotherapy with a nitrogen-cooled cryoprobe (2.5 mm2 contact area) caused severe damage, resulting in phthisis bulbi. Another nitrogen-cooled probe (contact area of about 1 mm2 diameter) resulted in a permanent reduction in intraocular pressure, but the anterior parts of the lens became opaque. Histopathology revealed total necrosis of the ciliary epithelium and the basal membrane. Three months after cyclocryotherapy of this type the ciliary processes were atrophic and covered with connective tissue and regeneration of epithelial cells was not found in areas of such cryotherapy scars. Further experiments have been commenced including a reduction of application time, in order to find the optimum application technique resulting in permanent intraocular pressure reduction and the fewest possible side effects. PMID- 6910357 TI - Effects of commercial ophthalmic drugs on rabbit corneal epithelium. A scanning electron-microscopic study. AB - Surface changes on rabbit cornea were studied by scanning electron-microscopy after instillation of commercial corticosteroid and antibiotic collyria extensively used in ophthalmic practice. All the collyria caused loss of surface microvilli and cell damage. The collyrium containing dexamethasone, neomycin, and benzalkonium chloride caused less damage than similar collyrium with polymyxin, but without dexamethasone. On the other hand the collyrium containing dexamethasone and neomycin was still less damaging than similar collyrium with benzalkonium chloride as preservative. Chloramphenicol with dexamethasone caused damage similar to collyria containing dexamethasone, neomycin, polymyxine B sulphate, and benzalkonium chloride. PMID- 6910356 TI - The histopathology of cystoid macular edema. AB - The pathological findings in ten eyes with cystoid macular edema are used to demonstrate typical details, stages and clinical associations. A history of ocular hypotony leads the list of associated conditions. Cyclitis is also very common. Separation of the central cones from the pigment epithelium due to folding of the outer retinal layers is observed and this can be used to explain early central vision loss associated with cystoid macular edema. PMID- 6910358 TI - Extrusion of lysosomal bodies from apical mouse retinal pigment epithelium. AB - The retinal pigment epithelium (RPE) of 1- 24-month-old CF-1 mice was examined by both light and electron microscopy. Measurement of the area occupied by lysosomal bodies was carried out using a semiautomatic quantitative picture analyzing system (Kontron-EKO). Accumulation of lysosomal bodies in the apical RPE cytoplasm was the most characteristic feature in eyes over 12 months of age. The relative volume of lysosomal bodies to each RPE cytoplasm was maximal in 24-month old mice RPE, approximately three times that of 3-month-old mice. Complicated lysosomal bodies and small lysosomal bodies were also observed in the dilated microvilli, in the apices of the apical RPE cytoplasm and in the subretinal spaces in eyes over 18 months of age. The passway and extrusive mechanism of lysosomal bodies are discussed. PMID- 6910360 TI - [A method of standardizing the results of quantitative chemical investigations on material gained from vitrectomy (author's transl)]. AB - In this study a method is described which allow conclusions to be drawn from the concentration of chemical substances in the material gained from vitrectomy in relation to the content of these substances in the whole vitreous body. In 16 pairs of human postmortem eyes enucleated 3-5 h after death one eye of each pair was subjected to vitrectomy under constant suction and infusion pressure and cutting rate; the duration of surgery varied (3-9 min) and in each fellow eye the whole vitreous body was removed. Comparison of the different concentrations of chemical substances in the samples showed that they could be correlated. PMID- 6910359 TI - Mediation of the ocular response to cyclocryocoagulation. AB - The possible roles of prostaglandins and a neural pathway in the disruption of the blood-aqueous barrier in the rabbit eye after cyclocryocoagulation were studied. Both the preoperative IV administration of the prostaglandin inhibitor acetylsalicylic acid and the application of retrobulbar and topical anesthesia reduced IOP and decreased breakdown of the blood-aqueous barrier, as measured by protein in the aqueous humour. These results imply that the acute response of the animal eye to cyclocryocoagulation is mediated partly by prostaglandins and partly by a neural component resistent an inhibitor of prostaglandin synthesis. When administered together, acetylsalicylic acid and ocular anesthesia yielded a further reduction in postoperative reactions and protein concentrations in the aqueous humour, but were unable to abolish the ocular response completely. The dual ocular mediation to cyclocryocoagulation is apparently due to the combined thermal and mechanical injury caused to ocular structures which synthesize prostaglandins and receive sensory innervation from the trigeminal nerve. The considerable breakdown of the blood-aqueous barrier in cyclocryocoagulation allows leakage of different molecular weight proteins, in equal ratio, into the aqueous humour. PMID- 6910361 TI - [Quantitative chemical analyses on the material gained by vitrectomy (author's transl)]. AB - The material gained by vitrectomy from 13 eyes suffering from different pathological changes of the vitreous body was analysed in relation to the concentrations of protein, lactic acid and glycogen, and standardized by means of a special method. The concentration of protein was found to have increased in cases of intravitreal haemorrhage, shrinkage of the vitreous body after complete spontaneous resorption of intravitreal haemorrhage, and in a case of intravitreal membranes following endophthalmitis; in cases of subvitreal haemorrhage the protein content was approximately normal. The concentrations of lactic acid and glycogen were examined to find out if anaerobic glycolysis could be proved in cases of ischaemic retinopathy. Only one case showed an increased concentration of lactic acid while in three cases there was a reduced content of glycogen. In these three cases the possibility of anaerobic glycolysis could not be excluded, because in rabbits a rapid excretion rate of increased lactic acid concentrations via retinal vessels has been reported. PMID- 6910363 TI - Effects of vitrectomy and phakectomy on the drainage of the vitreous compartment. AB - Plastic microspheres (7-10 micrometers in diameter), 51Cr-labeled autologous red blood cells (RBC), and 125I-tagged homologous albumin were injected into the vitreous space of vitrectomized phakic and aphakic rabbits. The drainage into the aqueous compartments and blood circulation was assessed. In phakic eyes, there was practically no movement of microspheres and RBC into the anterior chamber over a period of 19 days. In aphakia, vitreous clearance improved but only 1%-3% of labeled RBC appeared in the blood circulation during the first 3-4 days. About 40%-70% of the 125I-albumin injected left the eye within 24 h, as compared to 15% 25% in phakic rabbits. Thus, a vitrectomy in phakic eyes does not lead to anterior drainage of intact RBC and even after combined vitrectomy and phakectomy, the drainage of RBC is not complete; the elimination of albumin is greatly enhanced after vitrectomy. PMID- 6910365 TI - Economic stress and families: introduction. PMID- 6910362 TI - [Changed retinal cell content in diabetics (author's transl)]. AB - A quantitative exploration of retinal cell content was carried out in diabetics and metabolically healthy controls of the same age and sex distribution. After diabetes of 6 years duration there was a drastic diminution of cells in the ganglion cell layer of the central retinal area, while the number of cells of the inner nuclear layer was slightly reduced and that of the outer nuclear layer was still unchanged. The periphery of short duration diabetic retinae showed a normal cell content in all nuclear layers. In long-term diabetes (about 10 years), significant diminutions in cell numbers were found in all layers of both the retinal center and periphery. The described cell deficits are accounted for by disturbances of retinal microcirculation. After a relatively short duration of diabetes, blood flow interruptions in the area supplied by the central retinal artery occur; in long-term diabetics the chorioidal vessels are also affected. Connexions between the cell-deficit pattern and functional (electrophysiological) findings are discussed. PMID- 6910364 TI - Research priorities for the 1980s: generating a scientific basis for nursing practice. PMID- 6910366 TI - Some effects of changes in natural resources on clients in a public health nursing practice. PMID- 6910367 TI - Income, mothers' mental health, and family functioning in a low-income population. PMID- 6910368 TI - The impact of changing resources on health care of the future. PMID- 6910370 TI - Conserving educational resources: a community-based model for an outreach master's program in nursing. PMID- 6910369 TI - Energy-related stress and families' coping response. PMID- 6910371 TI - Cost containment: impact on nursing service and nursing education. PMID- 6910372 TI - A statement on the scope of gerontological nursing practice. PMID- 6910373 TI - Kallikrein and male subfertility. Usefulness of high-unit kallikrein tablets. AB - We studied the therapeutic effect of long-term oral administration of Kallikrein tablets on male subfertility. Subjects were 26 patients with poor sperm motility and divided into two groups according to the rate of motile spermatozoa: less than 40% (Group A: 9 cases) and 40% or more (Group B: 17 cases). Patients in Group A administered with 600 K.U./day orally for 6 months and those of Group B received 300 K.U./day for initial 3 months and 600 K.U/day for the ensuing 3 months. The changes of semen parameters during the treatment were as follows. a) No increase in sperm count. b) significant improvement of quantitative and qualitative sperm motility. c) Improvement of sperm morphology. d) Significant increase in total number of motile spermatozoa. e) Volume of semen was increased without statistical significance. Testosterone, FSH, and LH levels in blood plasma did not change significantly. The constituents of seminal plasma (fructose, cholesterol, ALP, ACP, GOT and LDH) were determined. Although ACP and GOT showed an increasing tendency and ALP tended to decrease during treatment, we found no biochemical parameter changing parallel with therapeutic results. Eight out of the 26 subjects successfully impregnated their wives (conception rate: 30.8%). No remarkable side effect was detected. PMID- 6910375 TI - Japan: seeking the best of a growing profession. PMID- 6910376 TI - Finland: new focus on prevention calls for changes. PMID- 6910374 TI - E&GW study raises questions for ANA. PMID- 6910377 TI - Jamaica: professional progress, care for all are goals. PMID- 6910378 TI - England: a lighthearted view of American nursing. PMID- 6910379 TI - Italy: better education, expanded nursing services are key issues. PMID- 6910380 TI - ICN Congress salutes spirit, tradition of nursing. PMID- 6910381 TI - India: nurses provide curative, preventive, rehabilitative care. PMID- 6910382 TI - An interview with Mary Opal Wolanin. PMID- 6910383 TI - Answers to questions on dental health care. PMID- 6910384 TI - Nursing aspects of the Jamison Report of Hospital Efficiency. PMID- 6910385 TI - Where do I stand? The nurse & the law. PMID- 6910386 TI - The application of ILO Conventions and Recommendations: role of the workers' organizations. PMID- 6910387 TI - The American way. PMID- 6910388 TI - Tamoxifen. The Royal Melbourne Hospital Pharmacy Department. PMID- 6910389 TI - A trial of a transparent adhesive dressing ("Op Site") in the treatment of decubitus ulcer. PMID- 6910390 TI - The role of values in the nursing curriculum. PMID- 6910391 TI - The expanding role of the occupational health nurse. PMID- 6910392 TI - The relationship between the bodies of knowledge of medicine and nursing. PMID- 6910394 TI - How to treat your guest speaker. PMID- 6910395 TI - The nurse as an agent of social change. PMID- 6910396 TI - The 'Jamison report'--a nagging query. PMID- 6910393 TI - Perspectives on the father's childbearing role. PMID- 6910397 TI - Let's remember the spiritual and emotional needs of the patient. PMID- 6910398 TI - Maternity leave. PMID- 6910399 TI - Demonstration project--the home health aide as part of the domiciliary care team. PMID- 6910401 TI - The American way. PMID- 6910400 TI - A hard day's night. PMID- 6910402 TI - Melioidosis: a not so rare tropical disease. PMID- 6910403 TI - Patients' responses to stoma therapy: suitable only for loners. PMID- 6910404 TI - Emerging trends in nursing. PMID- 6910405 TI - Student stress. A pilot study comparing stress in nursing students undertaking hospital-based and tertiary college basic nursing programmes. PMID- 6910406 TI - Prevention and control of cross infection. PMID- 6910407 TI - Society's view of nurses and their education: to see ourselves as others see us. PMID- 6910408 TI - Consumerism in health--are we accountable and if so, how? PMID- 6910409 TI - Nurse counselling. PMID- 6910411 TI - The Leboyer birth: an assignment for postgraduate course in midwifery. PMID- 6910410 TI - The people who aren't there. PMID- 6910413 TI - Crisis intervention in an adult burns unit. PMID- 6910412 TI - Schizophrenia: the bias is hope. PMID- 6910414 TI - Aboriginal customary law--recognition. PMID- 6910415 TI - To run or not to run - that is the question and reply: ascorbate (Vit. C) utilisation and stressful physical exertion. PMID- 6910416 TI - How safe is your home? PMID- 6910417 TI - Crime: how you can help prevent it. PMID- 6910418 TI - Women's access to justice. PMID- 6910419 TI - Special role and responsibilities. PMID- 6910421 TI - The "iatrogenic disease" controversy. PMID- 6910420 TI - Vitamin C: the dangers of calcium and safety of sodium ascorbate. PMID- 6910422 TI - Vaccinia viral core inhibits Met-tRNA.40S invitation complex formation with physiological mRNAs. PMID- 6910423 TI - Protection of human plasma kallikrein from inactivation by C1 inhibitor and other protease inhibitors. The role of high molecular weight kininogen. AB - High Mr kininogen increases the activation rate of prekallikrein by activated factor XII on a surface. The resulting serine protease, plasma kallikrein, Mr 88 000, is inhibited in plasma by C1 inhibitor, Mr 105 000. Since prekallikrein circulates in plasma with high Mr kininogen as a complex and a kallikrein-high Mr kininogen complex can be formed in purified systems, we studied whether the inhibition of kallikrein by C1 inhibitor was influenced by high Mr kininogen. With C1 inhibitor in excess, the inactivation of kallikrein followed pseudo-first order kinetics. The second-order rate constant for the reaction was 1.7 X 10(4) M 1 s-1, and a kallikrein-C1 inhibitor complex, Mr 190 000 was identified on polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. Kallikrein and C1 inhibitor formed an irreversible complex without measurable prior equilibrium. The rate of this reaction was decreased by 50% in the presence of high Mr kininogen (1 unit/mL or 0.73 muM). Kinetic analysis indicated that this protection was the result of the formation of a reversible complex between kallikrein and high Mr kininogen, which had a dissociation constant of 0.75 muM. However, low Mr kininogen did not protect kallikrein from inactivation by C1 inhibitor. High Mr kininogen also protected kallikrein from inactivation by diisopropyl fluorophosphate. These findings suggest that the kallikrein-high Mr kininogen complex was formed by noncovalent interactions between the light chains of both kallikrein and high Mr kininogen. PMID- 6910424 TI - A new class of synthetic elastase inhibitor. PMID- 6910425 TI - [Biological activity of hepatic transfer RNA of rabbits of different ages]. PMID- 6910428 TI - Studies on Kallikreins. VI. Effect of pancreatic kallikrein and kinin on the transport of amino acids and glucose across the rat small intestine. PMID- 6910427 TI - The foetal transfusion syndrome. A report of two cases. PMID- 6910429 TI - Detection and elimination of serum protein contaminants during the purification of human urinary kallikrein. PMID- 6910430 TI - Biosynthesis of complement by human monocytes. PMID- 6910426 TI - Transient conformational states in proteins followed by differential labeling. AB - Refolding of previously denatured and reduced elastase has been followed by titration of chemical reactivities of amino acid side chains to study the topography of the protein in the native state, and the microenvironment variations of protein side chains during the structural transition. Groups accessible to chemical reagents in the denatured form and buried in the "native" form were used as a local conformational probe. Times of labeling, depending on the reagent used, ranged from 100 to 800 ms. The reaction was stopped by isotopic dilution with an excess of unlabeled reagent under denaturing conditions to obtain a chemically homogeneous but heterogeneously labeled material. Peptide fractionation after degradation of the labeled proteins allowed the determination of the amount of radioactive label incorporated by the individual side chains during the refolding. Refolding rates, determined by physicochemical, enzymatic or immunochemical criteria, were compared with the conformational states of protein areas and evaluated by the variation of chemical reactivity at various denaturant concentrations. The importance of the last folding stages is emphasized by the results obtained which indicate that early during the refolding, two domain substructures (H-40 to H-71 and M-180 to H-200)( are stabilized, while the protein remains inactive at the time ranges of the labeling reactions. PMID- 6910431 TI - Caustic ulcers from lime dust. PMID- 6910433 TI - [Biliary tract dyskinesia]. PMID- 6910432 TI - The effect of elastase on pulmonary elastin and collagen: comparison of intravenous and intratracheal exposure. AB - Intravenous injection of exogenous pancreatic elastase to hamsters within tolerable limits (up to 133 units/100 g animal) induced no significant changes in lung elastin as compared with the controls whereas intratracheal injection of a much smaller amount of enzyme (5 units) caused a remarkable decrease in total elastin within 24 hr. Decrease in lung collagen is observed by both routes of elastase injection only at the highest tolerable level of enzymes utilized (28 U IT and 133 U IV). The large differences in the tolerable limits of IV and IT injections of elastase may be ascribed to large differences in dilution volumes encountered in the vascular circuit as compared to the airways and to the nature and amounts of elastase inhibitors in serum as opposed to pulmonary fluid. Collagenase impurities in the elastase may also be in part responsible for the observed biochemical changes in lung collagen. PMID- 6910435 TI - [Vomiting in pregnancy]. PMID- 6910434 TI - [Diabetes mellitus and its therapeutic nutrition]. PMID- 6910436 TI - [Myopia and pregnancy]. PMID- 6910437 TI - [Overheating in children]. PMID- 6910438 TI - [Organization of medical care for children with chronic gastroenterologic diseases]. PMID- 6910439 TI - [Measles]. PMID- 6910440 TI - [Raynaud's disease]. PMID- 6910441 TI - [Providing aid before the hospital stage to children with water hemlock poisoning]. PMID- 6910443 TI - [Blood components and preparations]. PMID- 6910442 TI - [First aid for acute epididymitis]. PMID- 6910445 TI - [Propagandizing the health life style]. PMID- 6910444 TI - [Hygienic training of milkmaids]. PMID- 6910446 TI - [Role of hypothalamo-hypophyseal disorders in the pathogenesis of menstrual function disturbances]. PMID- 6910447 TI - [Cardiac-type neurocirculatory dystonia]. PMID- 6910448 TI - [Role of the kallikrein-kinin system in achieving the hemodynamic effects of catecholamines]. PMID- 6910449 TI - [Motor activity of bile-excreting system following activation of kininogenesis]. PMID- 6910450 TI - [Interchange of babies in Portugal by exclusions in the ADA, GPT, ESD and HLA systems (author's transl)]. AB - The suspicion of an interchange of babies in two Portuguese families could not be dissipated in the first course of testing the following systems being considered: AB0, MNSs, Rhesus, Kell, Cellano, Duffy. Including further markers in an additional opinion, multiple father- and mother-exclusions could be made in the systems of ADA, GPT, EsD, and HLA. The suspicion thus showed to be justified and the children were given back to their natural parents. PMID- 6910451 TI - [Human placental lactogen and free estriol in maternal blood before and after external version of the fetus from breech to vertex presentation near to term (author's transl)]. AB - In 51 patients with 53 external versions of the child from breech presentation to vertex presentation near to term under tocolysis, the maternal serum-level of human placental lactogen (HPL) and free estriol (E3) was examined immediately before attempting the version and also 30 minutes and 60 minutes after the version, in order to find out whether these two parameters vary according to stress made on the placenta and fetus. In the whole group these were no significant differences in the HPL and estriol levels 30 and 60 minutes after the version compared with the levels before the version. Furthermore comparisons made with attempted versions with heavier stress on the placenta, such as anterior wall placenta, small volume of amniotic fluid, longer duration of the version, and placenta insufficiency did not lead to any significant HPL or estriol decrease in these groups. PMID- 6910452 TI - [The antenatal ultra-sonic diagnosis of ascites in the newborn (author's transl)]. AB - The antenatal diagnosis of fetal ascites by ultrasonography is possible by the typical finding of a zone free of echos in the fetal abdomen. Among 7,833 newborns 2 live born infants with fetal ascites were observed. The fetal prognosis can be improved by early diagnosis and differential diagnostic tests during the pregnancy. The antenatal diagnosis includes a search for hydrops, congenital anomalies of the heart, anomalies of the lower urinary tract, intra abdominal calcifications and diagnosis of the sex. Infectious causes such as syphilis, toxoplasmosis, cytomegaly and hepatitis must be excluded. Delivery may have to be by cesarean section paracentesis of the fetal ascites through the maternal abdominal wall may be necessary. A neonatalogist must be present at birth. The neonatal diagnosis of the ascites starts with a flat plate of the abdomen in search of calcifications, bowel distensions, and pneumoperitoneum. Intravenous pyelogram and cystography show urine-ascites which has the best therapeutic prognosis. The investigation should be finished within 12 hours after birth. Acute respiratory distress may require neonatal paracentesis. PMID- 6910453 TI - [Ultra-sonographic diagnosis of a thoraco-gastroschisis (author's transl)]. PMID- 6910454 TI - [The direct fetal electrocardiography following intra-uterine fetal death (author's transl)]. AB - During labor the maternal cardiogram was traced through the dead fetus. The technical prerequisites for this phenomenon are described. The concomitant intra uterine tracings of the contractions showed decelerations during the contractions in the maternal cardiogram obtained from the dead fetus. Similar observations have been described by other authors. The etiology of maternal cardiographic decelerations during the contractions is discussed. Decelerations in the maternal cardiogram traced from the dead fetus during labor may result in misinterpretations which lead to inappropriate obstetric management. PMID- 6910455 TI - [A rare dicephalous monster (author's transl)]. PMID- 6910456 TI - [Early complications after intra-cervical application of prostaglandin F2 alpha gel for therapeutic abortion (author's transl)]. AB - The intracervical application of prostaglandin F2 alpha gel reduced the hospital stay compared to previous methods of therapeutic abortion by one day. The operative technique of the therapeutic abortion is simplified by the medical dilatation of the cervix by the prostaglandin gel. The early complication rate was 10% initially but was reduced to 5% when the application time of prostaglandin gel was reduced from 18 to 14 hours and suction curettage introduced instead of sharp curettage. The side effect rate of the prostaglandin gel was relatively high with 14%. Many patients complained about severe labor like pain which responds poorly to analgesics. Therefore the application of intracervical prostaglandin gel is only recommended for therapeutic abortions beyond nine weeks gestation. Prior to nine weeks gestation suction curettage only is recommended. PMID- 6910457 TI - [On the dispersion capacity of an intra-vaginal contraceptive ovule. Results of an in-vivo study in sexually not stimulated women (author's transl)]. AB - In 62 sexually mature women in the out-patient department the intra-vaginal contraceptive ovule was inserted by the physician into the posterior vaginal vault and removed 15 minutes later and then weighed. The mean loss of weight was about 24%. Except in one case the ovule remained intact in all other cases the foam development was confined to the upper third of the vagina. With a probability of error of P = 0.12 it can be assumed that the dispersed amount from the ovule is less in older patients than in younger patients. There was no difference in the dispersed amount during in the first and the second half of the menstrual cycle. Further in-vivo investigations on intra-vaginal contraceptive ovules appear to be required. PMID- 6910458 TI - [Continuous differential-cytological control examinations of light dysplasia processes (author's transl)]. PMID- 6910459 TI - [Monitoring of post-operative prevention of thrombosis by low dosage heparin with the radioactive iodine fibrinogen test (author's transl)]. AB - In a prospective study low dosage subcutaneous heparin was administered to 148 patients after major gynaecological operations. The preventive effect on deep vein thrombosis was monitored by the radioactive iodine fibrinogen test. In 10.1% (15) of the cases higher than normal activity of the radioiodine fibrinogen test was detected. Only 4 patients (2.7%) had clinical signs of deep vein thrombosis. Because of the early occurrence of silent signs of deep vein thrombosis in the radioactive iodine fibrinogen test the onset of the subcutaneous heparin prophylaxis of thrombosis was shifted from the post-operative period to the pre operative administration. PMID- 6910460 TI - [A case of spontaneous perforation of a tension ulceration of the posterior vaginal vault in procidentia with subsequent small bowel prolapse (author's transl)]. AB - A case of spontaneous perforation of a tension ulceration in procidentia in an 82 year old woman is reported. A similar case has not been reported in the literature. The extra-ordinary rarity of this observation justifies the publication of this case. The main etiologic factor is considered to be a local perfusion problem of the tissue due to arterial sclerosis of the terminal vessels of the area. The small bowel was replaced. The uterus was replaced. A vaginal packing with clauden and later local treatment of the vaginal ulcers resulted in spontaneous closure of the fistula, histology of the margin of the fistula showed inflammation only and no malignant change. Treatment was completed by a subtotal vaginal colpocleisis according to Labhardt. PMID- 6910461 TI - [A new disposable, self-retaining, single-bladed vaginal speculum (author's transl)]. AB - A new, disposable vaginal speculum has been tested clinically. It consists of a thin, elastic plastic sheet which, rolled into the shape of a narrow tube, can be introduced into the vagina. Due to its inherent elasticity, it unfolds and allows examination of the cervix uteri. Of 507 patients investigated using this disposable speculum, cervical examination could be performed in 96%. In a comparative group of 138 patients using the usual metal speculum of Cusco, cervical examination was possible in 100%. The plastic speculum, developed for use in cancer screening tests, is suitable for routine vaginal examination after a little practice in the introduction technique. PMID- 6910462 TI - [Mortality as a central process in society (author's transl)]. AB - Population politicians and population planners face great difficulties in the realization of their goals. They are obliged to set preferences in their work such as an increase in the birth rate. They overlook that preferences are not empirical phenomena which can be measured in the same way as the rate marriage, death and birth. Therefore the population politician makes his decisions according to ideological concepts which is not too successful. Appeals to the common sense only surface old prejudices and views. The same is true of an appeal to religious principles. Myths, misconceptions and dubious rules of thumb are unnecessarily generated. An attempt is made to explain demographic problems in industrial societies with the example of the development of the death rate. The goal is to bring problems closer to a solution by documentation and interpretation which have far reaching consequences for the society and its economy. PMID- 6910463 TI - [Toxic shock syndrome in menstruating women]. PMID- 6910465 TI - [Bacterial penicillin-binding proteins as specific targets of beta-lactam antibiotics and as factors of resistance to antibiotics (author's transl)]. AB - Bacteria contain several isofunctional, beta-lactam sensitive membrane enzymes engaged in the synthesis of cell wall peptidoglycan (peptidoglycan-DD carboxypeptidases, -transpeptidases, -endopeptidases) as members of sets of even more numerous membrane proteins with specific, high binding-affinity for beta lactam antibiotics (penicillin-binding proteins, PBPs). Effective inhibition of bacterial growth by beta-lactam antibiotics requires simultaneous inactivation of the essential functions of several PBPs by formation of stable enzyme-antibiotic complexes. Failure to achieve permanent inactivation of all essential targets by a given beta-lactam appears to be another cause of bacterial beta-lactam resistance, in addition to known resistance mechanisms based on action of beta lactamases and on screening off targets from antibiotic by a penetration barrier. Different groups of beta-lactam antibiotics vary characteristically in their affinity for specific essential PBPs. Combined application of two beta-lactams which complement each other in the inactivation to essential targets is a possibility to overcome resistance of single antibiotics. PMID- 6910466 TI - [Diagnosis of eosinophilia]. PMID- 6910467 TI - [Catecholamines]. PMID- 6910464 TI - Red cell glyoxalase I polymorphism in Alsace, France: linkage of GLO with Bf. PMID- 6910468 TI - [alcohol, biology and health of the child. Part IV]. PMID- 6910469 TI - [Cardiac physiology--III]. PMID- 6910470 TI - [Status of fecal examinations]. PMID- 6910471 TI - [Blindness is often avoidable]. PMID- 6910473 TI - [Biological diagnosis of Vaquez' disease]. PMID- 6910472 TI - [The number of physicians per inhabitant remains insufficient in developing countries--no noticeable change tor the last 10 years]. PMID- 6910474 TI - The Guild in the future. PMID- 6910475 TI - The sanctity of human life. PMID- 6910476 TI - Differential polyamine inhibition of Met-tRNAMetf deacylation by prostate enzymes. PMID- 6910477 TI - Taxonomy of the antibiotic Bu-2313-producing organism. Microtetraspora caesia sp. nov. AB - An aerobic actinomycete strain isolated from an Indian soil sample and designated No. E864-61 was found to produce in submerged fermentation a new antibiotic complex, Bu-2313 (components A and B). Strain E864-61 forms single, pairs or chains of three to eight spores on the aerial mycelium and its aerial mass color is grayish blue-green. The cell wall of strain E864-61 contains meso diaminopimelic acid and galactose. Strain E864-61 has been classified as a new species of the genus Microtetraspora and designated as Microtetraspora caesia sp. nov. PMID- 6910478 TI - Close correlation between initiator methionyl-tRNA level and rate of protein synthesis during human lymphocyte growth cycle. PMID- 6910479 TI - Combination of minocycline and rifampicin against methicillin- and gentamicin resistant Staphylococcus aureus. AB - Methicillin- and gentamicin-resistant Staphylococcus aureus may remain sensitive to minocycline and to rifampicin. A study of growth curves has shown that at inhibitory concentrations (0.4 mug/ml), minocycline prevents the development of mutants resistant to rifampicin. PMID- 6910480 TI - Haplotype study of the HLA-A, B, C and Bf associations by the factorial correspondence analysis a study of 325 haplotypes. PMID- 6910481 TI - Complement receptor is an inhibitor of the complement cascade. AB - A glycoprotein from the membrane of human erythrocytes has been identified as a receptor for C3b (CR1). It promotes the dissociation of the alternative pathway C3 convertase C3b,Bb and the cleavage of C3b by C3b/C4b inactivator. We find that CR1 also inactivates the C3 and C5 convertases of the classical pathway. CR1 inhibits the consumption of C3 by C3 convertase EAC142 and enhances the decay of C4b,2a sites. On a weight basis, CR1 is approximately 5-10 times more active than C4 binding protein, a serum inhibitor of C4b,2a. The binding of 125I-CR1 to EAC14 cells is inhibited by C2. Therefore, it is likely that CR1 and C2 compete for a site on C4b. CR1 inhibited C5 convertase even more effectively, but had no effect on the assembly of the late complement components. At high concentrations, CR1 alone has no irreversible effects on cell-bound C4b. In the fluid phase, CR1 can function as a cofactor for the cleavage of the alpha' chain of C4b by C3b/C4b inactivator. A well-known function of CR1 is to promote adherence of microbes or immune complexes bearing C3b and C4b to cells. This interaction could result in a microenvironment damaging to the plasma membrane of the responding cell because the extrinsic C3b and C4b fragments can serve as additional sites of assembly of enzymes of the cascade. We therefore wish to propose that CR1 on the surface of cells supplies an increased local concentration of a strong inhibitor of the amplifying enzymes of the complement system and provides cells with a mechanism for circumventing damage when they bind C3b- and C4b-bearing substrates. PMID- 6910483 TI - [Link between medicine and biology]. PMID- 6910484 TI - [Man and ethology--behaviors of animals and man's volition]. PMID- 6910485 TI - [Creation of a clone man and human reproduction]. PMID- 6910482 TI - Chemotactic activity generated from the fifth component of complement by plasma kallikrein of the rabbit. AB - Rabbit plasma kallikrein incubated with rabbit C5 resulted in the generation of chemotactic and secretagogue activity for rabbit neutrophils. This effect on C5 appeared to be due to kallikrein itself and not to a contaminating enzyme, because it could be inhibited by anti-kallikrein IgG or by soybean trypsin inhibitor to the same extent the kinin generation by the same kallikrein preparation was inhibited by these agents. The chemotactic response was consistent with the generation of a C5a-like peptide from C5 because the effect could be partially inhibited by carboxypeptidase N and was related to the generation of a small (approximately 14,000 mol wt) fragment of C5. No direct chemotactic response was detectable for kallikrein, activated Hageman factor, high-molecular weight kininogen, or intact C5. Incubation of Kallikrein, high molecular weight kininogen, and Hageman factor together, so that activation of all three proteins occurred, did not results in the generation of detectable chemotactic activity. PMID- 6910486 TI - [The mechanism of aging and medical intervention]. PMID- 6910487 TI - [Hormone actions and growth in man]. PMID- 6910489 TI - [Nursing as a study of humanity and life science]. PMID- 6910488 TI - [Biohazard and bio-ethics--the position of the public]. PMID- 6910490 TI - [Guidelines for the nursing care of stroke patients]. PMID- 6910491 TI - [Effective nursing actions in connection with urination in the neurology department--on neurogenic bladder]. PMID- 6910492 TI - [Assistance in recovery of memory by a patient with a total loss of recall of his past]. PMID- 6910493 TI - [On the system of survival by man]. PMID- 6910494 TI - [Diagnosis and prognosis of burns--determination of the severity]. PMID- 6910495 TI - [Initial treatment of severe burns and the practice of intensive care]. PMID- 6910496 TI - [Physiopathology of shock associated with severe burns]. PMID- 6910497 TI - [Fluid therapy for patients with severe burns]. PMID- 6910498 TI - [The initial treatment of severe burns and practice of nursing]. PMID- 6910499 TI - [Problems in nursing care of patients with severe burns--reflection on the activities in the past year and an overview]. PMID- 6910500 TI - [Respiratory care and nursing of patients with airway burns]. PMID- 6910501 TI - [Characteristics and nursing of patients with facial burns]. PMID- 6910502 TI - [Nursing for prevention of kidney failure during the shock stage of burns--fluid therapy during shock]. PMID- 6910503 TI - [Rehabilitation of burn patients and associated nursing care]. PMID- 6910504 TI - [Conference: critical care and nursing of patients with severe burns--4 clinical cases]. PMID- 6910505 TI - [Science of symptomatology: hemorrhage. Bleeding and hemostasis]. PMID- 6910506 TI - [Science of symptomatology: hemorrhage. Disturbance of the consciousness level due to massive hemorrhage and nursing care--a case of Korsakoff syndrome]. PMID- 6910507 TI - [Bedside guidance concerning cardiac diseases. Heart failure]. PMID- 6910508 TI - [Patients' needs in the department of neurosurgery]. PMID- 6910509 TI - [In search of the ideal in nursing education--active nursing in the early days of modern nursing education]. PMID- 6910510 TI - [Notes in research]. PMID- 6910512 TI - [What is the literature?]. PMID- 6910511 TI - [Discussion on the "study on computation of nursing personnel required in a ward"]. PMID- 6910513 TI - [Re-evaluation of nursing in thoracic surgery]. PMID- 6910514 TI - [Report on the 6th Seminar of the Nursing Research Alumni. Learning from clinical training - learning while assuming responsibility of each case. Group discussion. II]. PMID- 6910515 TI - [Report on the 6th Seminar of the Nursing Research School Alumni. 2. Impression by an attendant]. PMID- 6910516 TI - [Report on the 6th Seminar of the Nursing Research Alumni. 2. A discussion at the conclusion]. PMID- 6910517 TI - [Record of clinical training in pediatrics: planning of teaching based on the nursing process record]. PMID- 6910518 TI - [Minerva's light. Unpretentious thoughts on nursing and man. (4). In Greece]. PMID- 6910519 TI - [In search of a new educational encounter. 3. Impression of a lecture]. PMID- 6910520 TI - [The nurse and humanity]. PMID- 6910521 TI - [re-evaluation of the course on comprehensive nursing theory in basic nursing education: the position of basic nursing study and its role]. PMID- 6910522 TI - [On nursing education: experience in the United States]. PMID- 6910524 TI - [Objects of understanding: analysis of fundamental life activities based on sociological phases]. PMID- 6910523 TI - [Impressions made by nursing students on inpatients]. PMID- 6910525 TI - [Education in anatomy: examples at Katsu-nan Hospital School of Nursing]. PMID- 6910526 TI - [Effective learning of nursing associated with art therapy at a psychiatric department]. PMID- 6910528 TI - [In search of a new educational encounter. 4. Methods of in-service training: progress of in-service training and improvement of clinical teaching]. PMID- 6910527 TI - [Minerva's light. Unpretentious thoughts on nursing and man. (5). The meaning of life]. PMID- 6910529 TI - [Medical topics: controversy concerning primary health care]. PMID- 6910530 TI - [Profile of a nurse: Ms. Hiromi Endo, who gave emergency care to a high school girl having a heart attack in a train]. PMID- 6910532 TI - [Medical topics - ultrasonic microscopy]. PMID- 6910531 TI - [Incidences of colonic cancer in married couples]. PMID- 6910533 TI - [Reports on the activities of the ILO]. PMID- 6910535 TI - [Social position and recognition of the nurse in the modern nursing history in Japan]. PMID- 6910534 TI - [Report on the 11th Congress of the Japan Nursing Association]. PMID- 6910536 TI - [Surveys on admission and graduation at nursing schools]. PMID- 6910537 TI - [Consideration for the others: an essay]. PMID- 6910538 TI - [Vocational aptitude in nursing and my personal experience]. PMID- 6910539 TI - [Notes on vocational aptitude]. PMID- 6910540 TI - [Without a superficial pretention of being a good nurse]. PMID- 6910541 TI - [Determination of vocational aptitude at admission to a nursing school]. PMID- 6910542 TI - [Tasks and overview of 1981. An interview with Ms. Omori, President of the Japanese Nursing Association]. PMID- 6910543 TI - [Nurturing the aptitude - at the educational scene]. PMID- 6910544 TI - [San Francisco Visiting Nurse Association]. PMID- 6910545 TI - [Vocational aptitude in nursing. A discussion]. PMID- 6910546 TI - [Nurse-related medical accident: incident due to a lack of nursing observation]. PMID- 6910547 TI - [Sexuality of the aged]. PMID- 6910549 TI - [Changes in the "life cycle" of women and the professional attitude of nurses]. PMID- 6910548 TI - [Nursing profession and the life cycle of women]. PMID- 6910550 TI - [The life cycle of women and nursing: development of maternal awareness and nursing]. PMID- 6910551 TI - [The life cycle of women and nursing: changes in the life cycle of women and the profession]. PMID- 6910552 TI - [Establishment of a professional status in nursing]. PMID- 6910553 TI - [Human science. Sex. 6. Sexuality]. PMID- 6910555 TI - [The nurse: a human existence within the system. (3). The system and man in the nursing profession]. PMID- 6910554 TI - [Bedside conference. Planning of clinical training in nursing. The nerves (1)]. PMID- 6910556 TI - [Focal points in nursing education. (12). Evaluation in nursing education]. PMID- 6910557 TI - [An "image" of nursing related to patients' characteristics]. PMID- 6910558 TI - [Problems and goals in clinical training--practice at our school]. PMID- 6910560 TI - [Re-evaluation of the nursing procedure. The procedure and standards in nursing]. PMID- 6910559 TI - [Re-evaluation of the nursing procedure. Needs and pitfalls in preparation of a nursing manual]. PMID- 6910561 TI - [Re-evaluation of the nursing procedure. A trial in planning a nursing procedure applying a flow chart]. PMID- 6910562 TI - [A concept of nursing procedure--from the viewpoint of hospital industrial engineering]. PMID- 6910563 TI - [Patient transfer--a day at the Kobe Shiritsu Chuo Shimin Hospital]. PMID- 6910565 TI - [The background for the birth of the nurse practitioner]. PMID- 6910564 TI - [An observation on nursing at a private hospital--with special reference to the result of survey on aged patients]. PMID- 6910566 TI - [Bedside conference: planning of clinical training. (4). The nerves (2)]. PMID- 6910567 TI - [The nurse: a human being within a system. Motivation and morale. (1)]. PMID- 6910568 TI - [Complications of bedrest]. PMID- 6910570 TI - Case history: Ima Howler--student nurse. PMID- 6910569 TI - Fifty years on: the state's first bachelor's degree in nursing. PMID- 6910571 TI - Tuberculosis--what's that? PMID- 6910572 TI - Your tax guide: a guide to help you prepare your 1981 Income Tax Return. PMID- 6910573 TI - [Intestinal dysbacteriosis]. PMID- 6910574 TI - [Rubella]. PMID- 6910575 TI - [Epidemic parotitis]. PMID- 6910576 TI - [Epidemic typhus and Brill's disease]. PMID- 6910577 TI - [Schedule of prophylactic inoculations in effect]. PMID- 6910578 TI - [Q fever]. PMID- 6910580 TI - [Prevention of plague]. PMID- 6910579 TI - [Clinical aspects, diagnosis and treatment of bovine-type brucellosis]. PMID- 6910581 TI - [Gas gangrene]. PMID- 6910582 TI - [Anatoxins and immune sera]. PMID- 6910583 TI - [Influenza]. PMID- 6910584 TI - [Differential diagnosis of balantidiasis]. PMID- 6910585 TI - [Yersiniasis]. PMID- 6910586 TI - [Diagnosis of acute intestinal diseases]. PMID- 6910587 TI - Alcohol and the unborn child. PMID- 6910588 TI - Effect of present patterns of maternity care on the emotional needs of mothers: Part 2. PMID- 6910590 TI - A three-week module for student nurses in the operating department. PMID- 6910591 TI - Fixation of an inter-trochanteric fracture by intermedullary nails of the Ender type. PMID- 6910589 TI - Isolation of globin pre-messenger RNA on thiol-agarose by terminally mercurated complementary DNA. AB - A mercurated DNA complementary to globin mRNA was prepared by the addition of mercurated poly(dC) tails to the 3'-end of the molecule using the enzyme terminal deoxynucleotidyl transferase. The mercurated complementary DNA was retained efficiently on thiol-agarose from which it was eluted by 2-mercaptoethanol. Hybridization of the mercurated probe to globin mRNA led to a specific selection of the latter from a mixed population of RNA through hybrid retention on thiol agarose. In some pilot experiments this technique was applied for the isolation of globin gene-specific pre-mRNA. Pulse-labeled RNA up to 3 X 10(6) MW was thus isolated with prominent peaks of 1.5 kb ('15 S'), 4.0 kb ('28 S') and up to about 10 kb. Electron microscopical analysis revealed pre-mRNA molecules of up to 1.2 mu (about 4.5 kb) in length isolated by hybridization to (Hg)cDNA; in control experiments, hybridization of this high MW RNA was competed out by highly purified globin mRNA. These data provide another indication for the existence of globin gene transcripts in the 10 kb range, i.e. transcripts larger than the about 1 500 nucleotides long '15 S' pre-mRNA, the substrate to final splicing. Such 'giant' transcripts can be interpreted as either the obligatory primary pre mRNA or only facultative transcripts of the globin genes. PMID- 6910592 TI - A study of day unit surgery in North America NATN/Surgikos Fellow Award winner 1979. PMID- 6910593 TI - Using video tapes to teach interviewing skills. PMID- 6910594 TI - Utilization of quality concepts in educational evaluation. PMID- 6910596 TI - Medication errors: always check for drug allergies. PMID- 6910595 TI - One of the "regulars". PMID- 6910597 TI - Cardiogenic shock: catch it early! PMID- 6910598 TI - Sam was dying... we had to help him live again. PMID- 6910599 TI - No need for space wars: a parable for our times. PMID- 6910600 TI - Don't combine those drugs (until you check this table). PMID- 6910601 TI - About using restraints--with restraint. PMID- 6910602 TI - Step by step...renew a patient's interest in life with an ambulation incentive program. PMID- 6910604 TI - Fighting fire: your role in hospital fire safety. PMID- 6910603 TI - In-line I.V. filters. Are they really worthwhile? PMID- 6910605 TI - Transferring patients safely and efficiently. PMID- 6910606 TI - When all else fails: continuous morphine infusion for controlling intractable pain. PMID- 6910607 TI - The power of positive suggestion: persuading patients to cooperate. PMID- 6910608 TI - Flagyl I.V., a new form for metronidazole. PMID- 6910609 TI - Test your knowledge of chest pain. PMID- 6910610 TI - Into the next century. PMID- 6910611 TI - Teacher activity analysis. PMID- 6910612 TI - Ward sisters and student nurses--a survey of attitudes. PMID- 6910614 TI - Liability of employing authorities for accidents at work. PMID- 6910613 TI - Higher education for nurses?--a student's view. PMID- 6910615 TI - A new concept: the new geriatric acute assessment unit at Hammersmith Hospital. PMID- 6910616 TI - Voice of the ward sister: from nursing officer back to ward sister. Interview by Celia Fairbrother. PMID- 6910618 TI - Intravenous therapy: the extended role of the nurse. PMID- 6910617 TI - Regional close-up: South Western Region. PMID- 6910619 TI - Management development workshop: 1. PMID- 6910620 TI - Voice of the ward sister. Interview by Celia Fairbrother. PMID- 6910622 TI - Analysis of 1980 salary survey of Northern California Association of Occupational Health Nurses. PMID- 6910621 TI - Regional close-up: southwest Thames. PMID- 6910624 TI - Insomnia: the common sense approach. PMID- 6910623 TI - What ANA accreditation means for AAOHN. PMID- 6910625 TI - Tetanus is still deadly. PMID- 6910626 TI - Job description: key to your future. PMID- 6910627 TI - Nursing perception needs changing. PMID- 6910628 TI - Cultures deserve dignity. PMID- 6910629 TI - Blood pressure measurement and hypertension in children. PMID- 6910630 TI - Canine and feline rivalry: another form of sibling rivalry. PMID- 6910631 TI - ABC for teens: parent education after the baby comes. PMID- 6910632 TI - Father/daughter incest: a family problem. PMID- 6910633 TI - Hyperactivity: a possible consequence of maternal alcohol consumption. PMID- 6910634 TI - The McCarthy scales of children's abilities: their usefulness in developmental assessment. PMID- 6910635 TI - Pediatric management problems (incest). PMID- 6910636 TI - Cathodal elastase in duodenal juice from children with gastrointestinal disorders. AB - Immunoreactive cathodal elastase, elastinolytic activity, and activity on the low molecular elastase substrate succinyl-trialanine were assayed in duodenal juice from 89 fasting children with different malabsorption problems. Cathodal elastase immunoactivity (mean value, 0.06 g/liter) averaged 1% of the total protein content in duodenal juice and 1/16 of the succinyl-trialanine-splitting activity. A strong influence of age was found for immunoactivity and elastinolytic activity, indicating continuing development of the cathodal elastase during the first 24 months of life. In 81 children with normal pancreatic function, significantly lower levels for all parameters including total protein were found for 14 with coeliac disease than for 34 children with unclassified gastrointestinal disorders and 33 with cow's milk protein intolerance. In eight children with pancreatic insufficiency, seven lacked detectable immunoactive cathodal elastase; low levels of succinyl-trialanine-splitting activity were found in six, and remnants of elastinolytic activity in three. PMID- 6910638 TI - Clones at Duke? PMID- 6910639 TI - Clones at Duke? PMID- 6910637 TI - Cross-linking of Met-tRNAf to eIF-2 beta and to the ribosomal proteins S3a and S6 within the eukaryotic inhibition complex, eIF-2 .GMPPCP.Met-tRNAf.small ribosomal subunit. AB - In the quaternary initiation complex, eIF-2.GMPPCP.Met-tRNAf.40S ribosomal subunit, the Met-tRNAf can be cross-linked to the beta subunit of initiation factor eIF-2 as well as to ribosomal proteins S3a and S6 by treatment with the bifunctional reagent, diepoxybutane. Using 40S subunits, modified in advance with the heterobifunctional reagent, methyl-rho-azido-benzoylaminoacetimidate, Met tRNAf is covalently bound to the same ribosomal proteins (S3a and S6) upon irradiation of the complex with ultraviolet light. Under both conditions proteins S3a and S6, together with a limited number of other ribosomal proteins, are covalently bound to 18S ribosomal RNA. PMID- 6910640 TI - Patients' work in the technologized hospital. PMID- 6910641 TI - Nursing's scientific quest. PMID- 6910642 TI - The postdoctoral research fellow in nursing: in between the cracks in the academic wall. PMID- 6910643 TI - Debate as a teaching-learning strategy. PMID- 6910644 TI - Reframing the issue: a debate on third-party reimbursement. PMID- 6910646 TI - The new breed. PMID- 6910645 TI - Responding to patients' concerns. AB - Training our nursing staff in reflective responding techniques was a worthwhile project, and patients are benefitting from a staff better prepared to help them cope with some of the emotional stresses they face. Staff members now possess some basic helping skills on which other counseling skills may be built and have eliminated many nonhelpful responses. The participants are more aware of their unique role in helping patients deal with feelings about illness. By using these helping behaviors nursing staff members fulfill an autonomous function in the health care field. "They feel satisfied because they are doing a good job." PMID- 6910647 TI - Nursing's image on campus. PMID- 6910649 TI - Self-directed learning: an option for nursing education. PMID- 6910648 TI - Gaps and contracts. PMID- 6910650 TI - Toward professional adulthood. PMID- 6910651 TI - To advance, we must unite. PMID- 6910652 TI - This is my colleague. PMID- 6910653 TI - Sugar'n' spice and all things nice? PMID- 6910654 TI - Change in the making. PMID- 6910656 TI - Communication skills: talking points. 23. Baby-talk rules OK. PMID- 6910655 TI - Nursing care study: tonsillectomy, adenoidectomy and bilateral myringotomy. PMID- 6910657 TI - Organising a library for the school of nursing. 4. Journals, indexes and abstracts; library orientation. PMID- 6910658 TI - Learning to cope with sickle cell disease--a parent's experience. PMID- 6910659 TI - Communication with psychogeriatric patients. PMID- 6910660 TI - The nursing process in action--4. The nursing process in a psychiatric context. PMID- 6910661 TI - Pressure sores--1. Thermography as a screening technique. PMID- 6910662 TI - Pressure sores--2. The value of the Norton score. PMID- 6910663 TI - Communication skills: getting it across (information giving - Part 1). PMID- 6910664 TI - The nurse's contribution to the Medical Research Council's trial for mild hypertension. PMID- 6910665 TI - Nursing care study: an electrical burn injury. PMID- 6910667 TI - The nursing process in action--5. Fully involved. PMID- 6910666 TI - Leg ulcers. PMID- 6910668 TI - A visit to a psychiatric hospital in Thailand. PMID- 6910669 TI - Improving practice by skill sharing. PMID- 6910670 TI - Restless feet, restless minds. PMID- 6910671 TI - Culture in the classroom. PMID- 6910672 TI - Prevention: WHO can turn on the tap? PMID- 6910674 TI - Nurses' ability to manage-- an answer to the critics. PMID- 6910673 TI - Tracheostomy. PMID- 6910676 TI - Vision: seeing is believing. PMID- 6910675 TI - Asian medicine--in the best of traditions? PMID- 6910677 TI - Subarachnoid haemorrhage: a family concern. PMID- 6910678 TI - Open to discussion--how to transfer long-stay patients into the community. PMID- 6910679 TI - Malignant cells and ectopic hormone production. PMID- 6910680 TI - The young adult with cancer: a developmental approach. PMID- 6910681 TI - Evaluation of TOUCH: an oncology self-help group. PMID- 6910682 TI - Evaluating quality-of-life in oncology patients: pilot observations. PMID- 6910683 TI - The development of support systems on oncology units. PMID- 6910684 TI - Determining the effectiveness of an ostomy care guide in facilitating comprehensive patient care. PMID- 6910686 TI - The ONS abstract review process a report from the 1981 Congress committee. PMID- 6910685 TI - Informational needs of the Oncology Nursing Society membership. PMID- 6910687 TI - Continuing education programs in cancer nursing: annual update and survey results. PMID- 6910688 TI - Reviewed research abstracts for the sixth congress: the process, a critique, and future directions. PMID- 6910689 TI - [Daily food ration]. PMID- 6910690 TI - [Rehabilitation after amputation of the extremities]. PMID- 6910691 TI - [Breast tumor patient]. PMID- 6910692 TI - [Patient safety]. PMID- 6910693 TI - [Education in the field of obstetrical nursing]. PMID- 6910694 TI - [Nursing care process: an analysis of the conceptual substance]. PMID- 6910695 TI - [Nurses look forward to correspondence courses]. PMID- 6910696 TI - [Half a century of a hospital]. PMID- 6910697 TI - [Method of operating has changed; an interview with the president of the National Council of the Trade Union of Health Service Workers, Dr. Janusc Biernacky]. PMID- 6910698 TI - [Inoculations against mumps]. PMID- 6910699 TI - [In the matter of an exceptional chance]. PMID- 6910700 TI - [Health protection system and nursing]. PMID- 6910701 TI - [Education for the caring function. III]. PMID- 6910702 TI - [Respiratory system diseases]. PMID- 6910703 TI - [Husband in the psychoprophylaxis of labor]. PMID- 6910704 TI - [Rehabilitation after spinal cord injuries]. PMID- 6910705 TI - [Fire hazard]. PMID- 6910706 TI - [They describe us the way they see us]. PMID- 6910707 TI - [Bases of the nursing process]. PMID- 6910709 TI - [Correspondence studies]. PMID- 6910708 TI - [Inoculations against rubella]. PMID- 6910710 TI - [Regulations have become outdated]. PMID- 6910711 TI - [Food preservation]. PMID- 6910712 TI - [Demands]. PMID- 6910713 TI - [In the matter of education]. PMID- 6910714 TI - [Prevention of birth injuries]. PMID- 6910715 TI - The influence of high and low sodium intake on blood volume in the dog. AB - Plasma volume and blood volume were measured using T-1824 in two groups of dogs which were kept on a diet differing only in its content of sodium chloride for periods exceeding six weeks. The group on low sodium intake received 0.55 mmol Na.g-1.day-1 and the group on high sodium intake received 12.4 mmol Na.g-1.day-1. Both plasma and blood volumes were distinctly greater in the group on high sodium intake than those in the group on low sodium intake, and there was no differences in the haematocrit between the two groups of dogs. It is concluded that a greater plasma volume and red cell volume resulted from high sodium intake than from low sodium intake. PMID- 6910716 TI - Effects of pregnancy on the febrile responses in sheep. AB - Pyrogens were injected into unshorn pregnant and non-pregnant Soay and Clun Forest sheep and the effects on rectal temperature and thermoregulatory mechanisms monitored. Plasma concentrations of unconjugated oestrogens, progesterone and cortisol were measured in the sheep tested in late pregnancy. The effect of pyrogens was also examined in ovariectomized ewes treated with oestrogen and with oestrogen plus progesterone. In contrast to reports of work on shorn sheep all sheep developed a fever even when close to term but the increase in peripheral vasomotor tone normally induced by pyrogens was attenuated in the pregnant Clun Forest ewes. The hormone-treated ovariectomized animals developed normal fevers and provided little indication of a possible relation between peripheral levels of ovarian steroids and the degree of fever. The question of whether an endogenous antipyretic substance is present in pregnant sheep is discussed. PMID- 6910718 TI - Role of dopamine in the diuresis caused by stimulation of atrial receptors. AB - The diuretic response to stimulation of left atrial receptors, by distending balloons located either at the pulmonary vein-left atrial junctions or in the body of the left atrium was studied during blockade of dopamine receptors using a continuous infusion o sulpiride in doses ranging from 0.632 to 5.153 mumol . kg-1 . min-1, in anaesthetized dogs. A diuretic response was obtained in each experiment of distension of the balloons: the response was similar to that observed in dogs without blockade of dopamine receptors and was not significantly related to the dose os sulpiride used. It is concluded that the diuretic response to stimulation of atrial receptors, known to be mediated by a blood-borne agent, is unlikely to be caused by dopamine. PMID- 6910717 TI - A horseradish peroxidase study of vagal motoneurones with axons in cardiac and pulmonary branches of the cat and dog. AB - The location, within the brain stem, of vagal efferent neurones with axons in the cardiac and pulmonary branches of the cat, and the cardiac branch of the dog, have been defined. Horseradish peroxidase was applied to the cut central ends of these vagal branches and, after an appropriate time, sections of the brain stem were examined for labelled cell bodies. Labelled cell bodies were found ipsilaterally in the dorsal motor vagal nucleus, the nucleus ambiguus and in the reticular formation between these two nuclei. We suggest that the dual location for cell bodies of vagal axons may represent a separation of somata with myelinated and non-myelinated vagal axons to the nucleus ambiguus and the dorsal motor vagal nucleus respectively. PMID- 6910719 TI - The role of renal nerves in the diuresis and natriuresis caused by stimulation of atrial receptors. AB - The diuretic response to stimulation of left atrial receptors by distending balloons located either at the pulmonary vein-left atrial junctions or in the body of the left atrium, was studied in anaesthetized dogs in which on kidney had been surgically denervated. In these dogs diuretic and natriuretic responses to stimulation of atrial receptors were obtained in the denervated and the intact kidney; both responses were significantly greater in the intact kidney than in the denervated kidney. In the denervated kidney the natriuretic response showed a significant correlation to increases in heart rate resulting from stimulating of atrial receptors. It is concluded that the renal nerves contribute significantly to the increases in urine flow and sodium excretion in response to stimulation of atrial receptors. In the denervated kidney, the diuresis appeared to be mediated by a humoral mechanism and the natriuresis was associated with concomitant increases in heart rate. PMID- 6910720 TI - The responses in renal nerves to stimulation of atrial receptors, carotid sinus baroreceptors and carotid chemoreceptors. AB - The reflex reduction in activity in renal sympathetic nerves in response to distension of small balloons in the pulmonary vein-atrial junctions was studied in dogs anaesthetized with chloralose; the carotid sinuses were isolated and perfused with blood. In the first group of dogs, the response to distension of the balloons was studied at different levels of carotid sinus pressure. In thirteen preparations of renal nerves in eight dogs the response was not significantly influenced when the mean carotid sinus pressure was changed from 9.5 kPa to 17.5 kPa, despite marked changes in control frequencies of activity in the nerves. In the second group of dogs, the response to distension of the balloons was studied when the carotid sinuses were perfused alternately with arterial and venous blood. In six preparations of renal nerves in five dogs the response was not significantly influenced when the blood perfusing the carotid sinuses was changed, despite marked changes in control frequencies of activity in the nerves. In a third group of dogs, the reflex reduction in activity in renal nerves in response to a step increase in pressure in one carotid sinus was examined at different levels of pressure in the contralateral carotid sinus. In six preparations of renal nerves in five dogs the response to an increase in pressure in one carotid sinus was significantly reduced when the mean pressure in the contralateral sinus was changed from 8.7 kPa to 17.1 kPa. It is concluded that there is no interaction between the projections of atrial receptors and carotid sinus baroreceptors or carotid chemoreceptors in their convergence on the same efferent renal neurones. PMID- 6910721 TI - Active transport of salicylate by rat jejunum. AB - Using an improved segmented flow technique the uptake of salicylate in low concentration (1-3 mM) by rat jejunum is found to be steady for ca. 30 min, and is proportional to lumen concentration. At higher lumen concentrations (6-8 mM) the rate of uptake falls from the beginning to very low levels. At low lumen concentrations the tissue fluid concentration rises to approximately three times the lumen concentration without significant effect on the uptake rate. This rise is an exponential function of the net water transport across the intestinal wall. The rate constant is of the same order of magnitude as those found earlier for equilibration of tissue fluid with glucose and wash-out of protein from the tissue fluid. The uptake of salicylate is inhibited irreversibly by 2,4 dinitrophenol (2-4 x 10(-5) M). PMID- 6910722 TI - Effect of dietary linoleic and linolenic acids on gestation and parturition in the rat. AB - Six rats fed a basal, purified diet low in essential fatty acids gave birth to a total of twenty-eight pups, of which twenty-six were born dead (range of two to six pups per rat) after a mean gestation of 24 days. A seventh rat carrying ten fetuses had a protracted process of parturition with dystocia. Six rats fed the basal diet supplemented with linoleate gave birth to a total of sixty-one pups of which fifty-seven were born alive (range of two to fourteen pups per rat) after a mean gestation of 21.8 days. Seven rats fed the basal diet supplemented with linolenate and carrying a total of sixty-three fetuses (seven to twelve per rat) had a protracted process of parturition with dystocia, and only one live and one dead pup were born (mean gestation of 22.8 days). At Caesarian operation a marked uterine inertia was noted. In four more rats where the supplement of linolenate was replaced by linoleate from the seventeenth day of gestation, parturition appeared normal and twenty-nine live and four dead pups were born. The occurrence of dystocia appeared to be related to the number of fetuses being carried to term. It is concluded that, in the rat, linolenate satisfies the requirement for the growth of mother rat and of the fetuses but is inadequate for the normal process of parturition, probably through inadequate production of the prostaglandins involved. There appears to be an obligatory requirement for linoleate at parturition. PMID- 6910724 TI - The short-latency respiratory response to sudden withdrawal of hypercapnia and hypoxia in man. AB - Five healthy young male subjects were maintained in a state of mild asphyxia (PA, CO2 approximately 45 torr, 6.0 kPa, PA, O2 approximately 50 torr, 6.6 kPa), i.e. with moderately strong drives from both arterial and intracranial chemoreceptors VT, TT and TI were recorded and V and TE derived breath by breath. The arterial chemoreceptor component was briefly and abruptly reduced, perhaps silenced, by two separate procedures, each repeated twenty-four times on each subject: B, removal of hypercapnia (two breaths hypoxia with PI, CO2 = 0 through a separate inspiratory line) and C, removal of asphyxia (two breaths O2). In control tests, A, the maintenance mixture was replaced by an identical mixture, using an identical manipulation. For each subject means of B and C were compared with means of A and with each other. Quick reflex changes (first three breaths) in V, VT and TE in tests B were not appreciably different from those in tests C in any subject; changes in TI were minimal in all. Thus removal of only the hypercapnic component of the arterial chemoreflex drive appears to be as efficient as the removal of both components simultaneously. PMID- 6910725 TI - Intracellular marking of identified neurones in the superficial dorsal horn of the cat spinal cord. AB - Intracellular iontophoresis of horseradish peroxidase has been used to mark identified neurones in the superficial dorsal horn of cats. The cats were anaesthetized with alpha-chloralose and paralysed with gallamine triethodide. Four specific nocireceptive neurones in the marginal zone and seven neurones in the substantia gelatinosa were recovered. One of the former and four of the latter are described in detail and are illustrated as reconstructions from serial sections. The results confirm previous conclusions that the substantia gelatinosa contains neurones classified as 'inverse' and that the nocireceptive neurones of lamina I are Waldeyer Cells. PMID- 6910726 TI - In vivo morphology and ultrastructure of thyroid autografts in rabbit ear chambers. AB - Partial thyroidectomies were performed in half-lop rabbits. Small pieces of thyroid tissue were grafted into fully healed Sandison--Clark rabbit ear chambers. Thyroid grafts were observed directly through the compound microscope and sequential observations were recorded on photographic films and video tapes, with grafts remaining undisturbed within their vascular bed. Circulation within grafts was established within 3-5 d post-operatively, and between the second and fourth week pulsatile lymphatics loaded with lymphocytes could be observed within the grafts. Moreover, initial cellular infiltration, epithelial cell necrosis and regeneration have been recorded. Clear spaces or droplets observed within the colloid in vivo are considered to correspond to histological features long considered to be artefacts. This technique allows a non-intrusive approach to the study of the thyroid gland and thus can be used in studies of in vivo thyroid physiology, pharmacology, pathology and therapy. PMID- 6910723 TI - The utilization of lactic acid by sheep in late pregnancy. AB - The irreversible loss of lactate and the respiratory exchange in four conscious ewes that were about 138 days pregnant were measured at least seven days after surgery. In addition, the uptake and net output of lactate and the net uptake of glucose and alanine by the gravid uterus and an upper hind limb (primarily skeletal muscle) were measured. Calculated heat production of the ewes was 496 kJ/d.kg 3/4; irreversible loss of lactate was 9.5 mumol/min.kg of which 73% was oxidized to CO2, contributing 9% to the ewes' CO2 production. About 2% of the glucose and 65% of the alanine was derived from lactate. Lactate was taken up by both the gravid uterus and the upper hind limb; output of lactate could have accounted for from 8-12% of glucose uptake by the gravid uterus but from 35-50% of that by the upper hind limb. The carbohydrate/O2 quotient was 1.07 for the gravid uterus and 0.35 for the upper hind limb. PMID- 6910727 TI - The effects of age on spatial frequency perception in human subjects. AB - Visual performance was measured in sixty-six subjects aged from 5 to 94 years. The curve of contrast sensitivity against spatial frequency was obtained for each subject. This curve had a peak contrast sensitivity in the 2-6 c/deg (cycles/degree) range with the fall-offs to either side of the peak described, on a double logarithmic plot, by straight lines. With advancing age, the position of the peak sensitivity remained unchanged but there was an overall decrease in contrast sensitivity. The highest spatial frequency which could be perceived remained constant up to 50 years, thereafter it fell with increasing age. The slope of the low frequency straight line remained unchanged while that of the high frequency straight line fell with increasing age, i.e. the loss of contrast sensitivity was greater for middle range spatial frequencies than for higher spatial frequencies. The possible site of these changes, i.e. the optics of the eye, the retina/brain or higher decision making centres, is discussed. PMID- 6910728 TI - Respiratory modulation by vagal afferents in pigs. AB - We have studied the role of pulmonary vagal afferents and baroreceptors of the aortic arch on control of breathing in anaesthetized pigs. As in other species (dog, cats and rabbits) the depth and rate of breathing was found to be controlled by a volume-related vagal feed-back loop from pulmonary stretch receptors. Rapid shallow breathing following histamine aerosol and phenyldiguanide i.v. (which are likely to stimulate pulmonary vagal irratant and J receptors) occurred through a decrease in the activation threshold of the inspiratory cut-off mechanism without altering the matching of inspiratory to expiratory time. These results are also similar to those found in cats and rabbits. Histamine caused an increase in pulmonary resistance and a decrease in compliance: these effects were partially vagally mediated and partially due to a direct stimulation of smooth muscles by the drug. It seems, from relating the respiratory to the vascular systemic effect of histamine administration, that pigs have a greater respiratory response than cats or rabbits. A stepwise decrease in blood pressure through haemorrhage under iso-PCO2 and iso-PO2 conditions was found to affect the matching of the expiratory to the inspiratory time without affecting the activation threshold of the inspiratory cut-off mechanism. PMID- 6910729 TI - Tolerance of high altitude acclimatized rats to blood loss at sea level. AB - After acclimatization to high altitude, the sea level haemorrhagic tolerance of rats was measured by determining the bleeding volume which resulted in death under anaesthesia following cannulation. For each animal this was recorded as a bleeding volume index (BVI), the total volume of blood lost per 100 g of body weight. The mean BVI of altitude acclimatized rats was greater than that for non acclimatized rats (P less than 0.001), showing that chronic exposure to altitude enabled the animals to tolerate more severe blood loss. Evidence is presented which suggests that the increased haemorrhagic tolerance resulted, in part, from an increased initial blood volume and an increased ability for arterial blood pressure regulation during haemorrhage. PMID- 6910730 TI - Effect of secretin on intestinal lymph flow and composition in the rat. AB - The effects of natural porcine and synthetic secretin, given by intravenous bolus or infusion, on intestinal lymph flow and protein composition in unanaesthetized rats were studied. Both forms of secretin increased lymph flow and protein output from the lymph fistula; dose-response relationships were determined. No change was observed in protein concentration in lymph or in the relative concentrations of large and small protein molecules during secretin-induced enhanced lymph flow, compared with the basal state. These results are in keeping with an increase in the functional exchange vessel area of the small intestine produced by secretin. It is possible that secretin may play a part in the hyperaemia and augmented intestinal lymph flow which occurs in the post-prandial period. PMID- 6910731 TI - Cardiovascular changes in elicited by vagal gastric afferents in the rat. AB - Cardiovascular changes elicited by gastric distension in the urethane anaesthetized rat are described. Heart rate changes were mediated via a vago vagal pathway with 'in-series' tension receptors in the stomach wall providing the afferent input and cholinergic cardio-inhibitory fibres forming the efferent pathway. Blood pressure changes occurred independently of the heart rate changes; the main afferent pathway was again vagal but the efferent outflow was non cholinergic and probably sympathetic. PMID- 6910732 TI - Reflex responses of single renal sympathetic fibres to stimulation of atrial receptors and carotid baro- and chemoreceptors. AB - Recordings were made of the discharge of single fibres from renal sympathetic efferent nerves in the anaesthetized dog. Stimulation of left atrial receptors by distension of small balloons at the junctions of the pulmonary veins and the left atrium resulted in a reduction in the discharge of one group of these single fibres and no change in the discharge of a second group of fibres. Bilateral occlusion of the common carotid arteries resulted in an increase in the discharge of all single fibres tested. All fibres tested which responded to stimulation of atrial receptors also responded to carotid occlusion. These results provide evidence for convergence of the central pathways from atrial receptors and baroreceptors on individual sympathetic efferent neurones. PMID- 6910733 TI - The effect of cooling on transmission of impulses in vagal nerve fibres attached to atrial receptors in the dog. AB - In anaesthetized dogs, the effect of graded cooling on the transmission of the maximum frequency of impulses, evoked by supramaximal stimulation, was studied in myelinated and non-myelinated vagal fibres attached to receptors in the atria. In these fibres, it is shown that first, there is a continuous relation between the maximum frequency of transmission of impulses and vagal temperatures ranging between 37 degrees C and the temperature at complete blockade (no conduction at 0.5 impulses . s-1) for these fibres; second, there is a direct relationship between the maximum frequency of transmission of impulses and the conduction velocity. It is concluded that the maximum frequency of transmission of impulses in vagal fibres attached to atrial receptors in the dogs is related to temperature and conduction velocity. This relationship between maximum frequency of transmission and temperatures provides a quantitative explanation for the previously observed effects of cooling the vagi on the responses to stimulation of atrial receptors which were used to show that the reflex increases in heart rate and reflex reduction in activity in renal nerves involved only atrial receptors attached to myelinated vagal fibres. PMID- 6910734 TI - Diuresis from stimulation of left atrial receptors: ADH and the Malpighian tubules of Rhodnius prolixus. AB - Stimulation of left atrial receptors causes a diuresis partly through a blood borne agent. Malpighian tubules of Rhodnius prolixus can detect a blood borne agent during the diuresis. It has been suggested that the agent is ADH but this is in dispute. In the present investigation, vasopressin (1-300 mu i.u. cm-3) was found to have no effect on Malpighian tubule secretion when added to plasma, Rhodnius Ringer and Rhodnius Ringer + 5-HT. In addition, it was shown that incubation with sodium thioglycollate of plasma samples obtained from anaesthetized dogs, before and during stimulation of atrial receptors by distension of a balloon in the lumen of the left atrium, did not abolish the differences between test and control plasma samples detected by the Malpighian tubules. It is concluded that differences in plasma detected by the Malpighian tubules and related to the diuresis which results from left atrial stimulation are not attributable to changes in concentration of ADH. PMID- 6910736 TI - Maternity leave: "earned time" and wages due. Case in point: Richardson v. St. Mary Hospital (627 p. 2d 1143--KANS.). PMID- 6910735 TI - Patient behavior: limits on R.N. liability. PMID- 6910737 TI - Breast surgery: inadequate consent = $600,000.00. Case in point: Kinikin v. Heupel, M.D. (305 N.W.2d 589--MINN.). PMID- 6910738 TI - Functions of preschool children's questions in coping with hospitalization. AB - This study was designed to determine the functions of hospitalized preschool children's questions. Subjects were 24 hospitalzied preschool children ranging in age from 3 years to 5 years, 11 months. Subjects' spontaneous questions, addressed to adults in a hospital setting, were recorded and categorized using Piaget's functional classification. The categories were: (a) causal explanation, (b) reality and history, (c) actions and intentions, (d) classification and evaluation, (e) rules, and (f) calculation. The frequency distribution of questions was determined by categories. The largest perentage of questions (53%) was about actions and intentions of persons, primarily hospital personnel. Small percentages dealt with classification and evaluation (13%) and reality and history (12%) Causal explanation questions (8%) were uncommon. A larger percentage of actions and intentions questions was found in the hospital than in nonstressful school settings. The findings suggest that hospitalized preschool children need orientation to the actions and intentions of personnel in regard to therapeutic activities, routine care, and play and social activity. PMID- 6910739 TI - Personal space preferences of hospitalized adults. AB - The questions addressed in this study were whether hospitalized adults' personal space preferences (PSP) differed between the hospital and home setting and whether these patients assigned different PSP to a nurse, doctor, family member, or stranger. The effects of age and sex of the subjects were also examined. Sixty subjects (30 men and 30 women) meeting selected criteria participated. The figure placement technique (Little, 1965; Guardo, 1976) was used to measure PSP. Data were analyzed using a four-factor ANOVA (age X sex X role X setting) with repeated measures on the last two factors. Main effects were found fer setting, F(1,54) = 11.54, p less than .001, and role, F(3,162) = 112.95, p less than .0001; no other variables approached statistical significance. The major findings indicated that preferred distances in the hospital were smaller than in the home and that in both settings the family member was placed closest to the "self" silhousette followed by a doctor, nurse, and stranger, respectively. PMID- 6910740 TI - Psychometrics in nursing research: construction of an interpersonal conflict scale. AB - A step-wise description of a self-report instrument to measure interpersonal conflict between marital partners illustrates the primary aspects of the development of a psychometric tool. Definition of the construct to be measured, formulation and classification of items, and appropriate methods to establish validity and reliability are discussed. Indications are considered for alternate forms of a scale, which include repeated measurement over time for the purpose of identifying patterns in human behavior in interaction within the family system. The procedure for constructing alternate forms of equal reliability is outlined. PMID- 6910741 TI - Job satisfaction of staff registered nurses in primary and team nursing delivery systems. AB - Job satisfaction for nurses in team and primary nursing delivery systems as measured by a human needs questionnaire was studied. Staff-level registered nurses from 27 units in a large research hospital completed a 22-item questionnaire. Each item measured present and desired job satisfaction and the importance of the item to the respondent. Data from 115 primary-system nurses and 65 team-system nurses were analyzed by Kruskal-Wallis tests of significance and chi-square contingency tables. Overall, primary-system nurses reported greater job satisfaction than team-system nurses. The primary system offered more opportunity for accountability and fulfilling higher level needs. Neither system provided sufficient opportunities for self fulfillment, decision-making, or independent judgment. The identified weakness of the primary system was the unmet need for supervision. Of all the nurses in this study, 75% were dissatisfied with the prestige accorded to them. PMID- 6910743 TI - [Nursing process]. PMID- 6910742 TI - Research publication credit assignment: nurses' views. AB - A national survey of 1,693 persons (primarily nurses) from eight target groups was done to assess views on publication credit assignment. Data were collected using scenarios in a questionnaire based on the instrument developed by Spiegel and Keith-Spiegel (1970). Scenario items and the percentages of 897 respondents selecting each response alternative are presented in an appendix. Response rates indicated that authorship credit assignment is an important issue for nurses functioning primarily in academic settings. Among items selected by 85% or more of 620 nurses in four subsample groups (American Academy of Nursing, Council of Nurse Researchers, authors, and nursing doctoral students) with response rates greater than 50%, 10 points of agreement were found. These points are summarized as possible guidelines for publication credit assignment. Few differences were found among scenario item responses of: (a) subjects classified as high and low publishers, (b) those with research as their major role responsibility and others, and (c) doctoral students and others. PMID- 6910744 TI - [Various aspects of education-service integration]. PMID- 6910745 TI - [Vomiting and hematemesis: general aspects and nursing care]. PMID- 6910746 TI - [Theoretical aspects of primary health care]. PMID- 6910747 TI - [Control of sterilization. Role of the nurse]. PMID- 6910749 TI - [Family planning: "Billing's" ovulation method]. PMID- 6910748 TI - [The inefficiency of pediatric nursing education in relation to the assistance to the parents]. PMID- 6910750 TI - [Nursing care of patients with senility]. PMID- 6910752 TI - [Nursing in a pediatric intensive care unit, beyond technical activities]. PMID- 6910751 TI - [Health education in a pediatric health center. The work of a voluntary nurse]. PMID- 6910753 TI - [Nursing students of the male sex: a problem in the teaching of obstetrical nursing?]. PMID- 6910754 TI - [Tools and procedures for research in psychiatric nursing. I. Classification of activities performed by psychiatric nursing personnel]. PMID- 6910755 TI - [Tools and procedures for research in psychiatric nursing. II. Inventory of possible situations in psychiatric nursing]. PMID- 6910756 TI - [Professional job satisfaction of the nurse. Study of psychosocial needs]. PMID- 6910757 TI - [Function of the hospital nursing staff. Emergence of a new activity: nursing research and of a new function: supervisory nursing]. PMID- 6910758 TI - [Amebiasis]. PMID- 6910759 TI - [Current aspects of salpingitis and its management]. PMID- 6910760 TI - [Therapeutics: non-steroid anti-inflammatory agents]. PMID- 6910761 TI - A celebration of life. PMID- 6910762 TI - Toward impeccable IV technique. The right things to say about IVs. PMID- 6910763 TI - Multiple emergencies? Don't panic! PMID- 6910764 TI - If a full-fledged disaster strikes. PMID- 6910765 TI - Hypochondriacs I have known--and learned to love. PMID- 6910766 TI - Nursing salaries: just beginning to catch up. PMID- 6910767 TI - Of course you can manage head trauma patients. PMID- 6910768 TI - Repair a Swan-Ganz? Why not? PMID- 6910769 TI - What to watch for with cimetidine. PMID- 6910770 TI - Getting the best of those difficult abdominal wounds, part two. A big payoff for painstaking care. PMID- 6910771 TI - Legally speaking: 1001 ways to land in court, Part two. PMID- 6910772 TI - Back to basics. Sound off! PMID- 6910773 TI - Sex Q & A. Frank answers to your most delicate patient-counseling questions. PMID- 6910774 TI - [Health and development in the Third World countries]. PMID- 6910775 TI - [In the sun, be reasonable]. PMID- 6910776 TI - [Home care services in the community of Frederiksberg, Denmark]. PMID- 6910777 TI - [The cousins of the Redon]. PMID- 6910778 TI - [To your health. For a different understanding of disease]. PMID- 6910779 TI - [Living at home in one's old age]. PMID- 6910780 TI - [As theater, as therapy]. PMID- 6910781 TI - [Prevention of cardiovascular disorders; myth or reality]. PMID- 6910782 TI - [Promoting thermalism in France]. PMID- 6910783 TI - [The paraplegic at the discovery of a new identity]. PMID- 6910784 TI - [Scabies and pediculosis]. PMID- 6910785 TI - Changes of urinary kallikrein and kinin excretions induced by adrenalin infusion in conscious dogs. AB - A subpressor dose of adrenalin (0.5 mg/h) infused intravenously into nine conscious trained dogs increased urine kinin excretion from 41 +/- 9 ng/h to 191 +/- 29 ng/h. The effect was abolished by phenoxybenzamin pretreatment (1 mg/kg). In alpha-blocked condition adrenalin increased urine TAMe-esterase activity from 12.7 +/0 2.3 mEU/h to 15.7 +/- 2.8 mEU/h whilst in beta-blocked condition the catecholamine decreased urine enzyme activity from 12.7 +/- 1.0 mEU/h to 11.7 +/- 1.1 mEU/h. Adrenalin invariably decreased urine sodium excretion. In comparable experiments with dopamin (1.0 mg/h) a slight natriuresis was observed, yet urine kallikrein and urine kinin excretions remained unmodified. PMID- 6910786 TI - [Rehabilitation of breast cancer patients]. PMID- 6910788 TI - [Immunotherapy of cancer: what good does it do?]. PMID- 6910787 TI - [Radiotherapy: its effects on pathological and psychological aspects]. PMID- 6910789 TI - [Rehabilitation after treatment of ENT cancer]. PMID- 6910790 TI - [Evaluation of intake and output: the monitoring record]. PMID- 6910791 TI - [State Diploma of Nursing (examination subjects)]. PMID- 6910792 TI - [Radiography in injuries of the ankle]. PMID- 6910793 TI - [Treatment of benign and medium severe sprains of the ankle]. PMID- 6910794 TI - [Sprains of the knee and the ankle: a wellknown pathology of athletes]. PMID- 6910795 TI - [Surgical treatment of recent severe sprains of the ankle]. PMID- 6910796 TI - [Rehabilitation of ankle sprains]. PMID- 6910797 TI - [Clinical evaluation of knee sprains]. PMID- 6910798 TI - [Radiographic evaluation of recent ligament injuries of the knee]. PMID- 6910799 TI - [Treatment of knee sprains]. PMID- 6910800 TI - [Rehabilitation after severe knee sprain]. PMID- 6910801 TI - [Xylocaine]. PMID- 6910802 TI - [Benign sprain of the knee not necessitating surgical intervention]. PMID- 6910803 TI - [Interrelations between the person cared for, the care given and the nurse]. PMID- 6910804 TI - [Clinical diagnosis of the severity of ankle sprains]. PMID- 6910805 TI - [Drug dispensing in the hospital: need for unit dosages]. PMID- 6910806 TI - [The risk of errors in carrying out drug prescriptions]. PMID- 6910807 TI - [Drug administration routes]. PMID- 6910808 TI - [Organization of the pharmacy in a Public Welfare hospital]. PMID- 6910809 TI - [Pharmacy at home; the emergency box]. PMID- 6910810 TI - [The nurse and drugs]. PMID- 6910811 TI - [The introduction of new drugs in therapeutics: a strict systematic regulation]. PMID- 6910812 TI - [Criteria for correct drug administration]. PMID- 6910813 TI - [The structure of nursing education in Belgium. Nursing legislation in Belgium. Nomenclature of Belgian hospital personnel]. PMID- 6910814 TI - [The medicine cabinet in the hospital]. PMID- 6910815 TI - [Death and care of the dying]. PMID- 6910817 TI - [Assistance in crossing the final stage]. PMID- 6910816 TI - [Practical problems occasioned by a death]. PMID- 6910818 TI - [Dying]. PMID- 6910819 TI - [Euthanasia]. PMID- 6910820 TI - [Various components of the sociological analysis of the nursing profession]. PMID- 6910821 TI - [Hygiene of food products and beverages. Legal basis]. PMID- 6910822 TI - [Facing death]. PMID- 6910823 TI - [The child and death: an interview with Doctor G. Raimbaud]. PMID- 6910824 TI - [Treatment of Hodgkin disease]. PMID- 6910825 TI - [Hodgkin disease: today a curable disease]. PMID- 6910826 TI - [Hodgkin disease: results of treatment: monitoring of the patient]. PMID- 6910827 TI - [Role of the nursing team in the day hospital]. PMID- 6910828 TI - ["Recovery" from Hodgkin disease]. PMID- 6910829 TI - [Hodgkin disease: general aspects]. PMID- 6910830 TI - [Oncovin]. PMID- 6910831 TI - [Utilization of a nursing record in a cardiology service. Evaluation of 4 years experience]. PMID- 6910832 TI - [Prevention of cerebrospinal meningitis]. PMID- 6910833 TI - [Hodgkin disease: clinical aspects, diagnosis and study of spread]. PMID- 6910834 TI - [Emergency resuscitation and transportation of the multiple injured]. PMID- 6910835 TI - [Assessment of lesions in the multiple injured]. PMID- 6910836 TI - [Practical management in the shock treatment unit]. PMID- 6910837 TI - [The multiple injured: first of all ensure survival]. PMID- 6910838 TI - [Surgical treatment of the multiple injured]. PMID- 6910839 TI - [First aid to the multiple injured]. PMID- 6910840 TI - [Hospitalization of a multiple injured in an intensive care unit]. PMID- 6910841 TI - [First hours of a multiple injured]. PMID- 6910842 TI - [The lateral safety position]. PMID- 6910844 TI - [Anguish of the patient and the family]. PMID- 6910845 TI - [Architecture and equipment of a shock treatment unit. An example: the Montfermeil Hospital Center]. PMID- 6910843 TI - [Abdominal puncture-lavage]. PMID- 6910846 TI - [The qualification certificate of the ambulance technician]. PMID- 6910847 TI - [The role of SAMU (Emergency Medical Health Services) in the treatment of the multiple injured]. PMID- 6910848 TI - [Laryngeal obstruction]. PMID- 6910849 TI - [Respiratory distress due to obstruction. Clinical symptoms]. PMID- 6910850 TI - [Airway obstruction: more emergency problems]. PMID- 6910851 TI - [Foreign bodies of the airways]. PMID- 6910852 TI - [Asphyxiating facial injuries]. PMID- 6910853 TI - [Heimlich maneuver: emergency technic for removing foreign bodies from the airways]. PMID- 6910854 TI - [Medical aspiration procedures and their utilization]. PMID- 6910856 TI - [Mayo's canula]. PMID- 6910855 TI - [Anatomy and physiology of the upper airways]. PMID- 6910857 TI - [Clearing the airways: management]. PMID- 6910858 TI - [Tracheotomy]. PMID- 6910859 TI - [Care of Mister B...]. PMID- 6910860 TI - [Auxiliary headquarters for medical regulation of the SAMU (Emergency Medical Health Services) and of "15"]. PMID- 6910861 TI - [Physiopathology of obstructions]. PMID- 6910862 TI - [Injuries of the tendons of the hand and their surgical treatment]. PMID- 6910863 TI - [The place of microsurgery in the treatment of hand injuries]. PMID- 6910864 TI - [Hand injuries: meticulous and specialized surgery]. PMID- 6910865 TI - [Operating room suite and traumatology of the hand]. PMID- 6910866 TI - [Management of a distal amputation]. PMID- 6910867 TI - [Evaluation of an apparently benign finger injury or injury of the metacarpus]. PMID- 6910868 TI - [A clinical case of fracture of the finger]. PMID- 6910869 TI - [The place of kinesitherapy in the treatment of hand injuries]. PMID- 6910870 TI - [The place of ergotherapy in the rehabilitation of the injured hand]. PMID- 6910871 TI - [The importance of the hand from a psychological viewpoint]. PMID- 6910872 TI - [Ether and fire hazard]. PMID- 6910873 TI - [Fractures of the metacarpal bones and the phalanges]. PMID- 6910874 TI - [Hypothalamo-hypophyseal-ovarian sterility]. PMID- 6910875 TI - [Tubal sterility]. PMID- 6910876 TI - [Uterine adhesions of traumatic origin]. PMID- 6910877 TI - [Education of midwives]. PMID- 6910878 TI - [Male evaluation of a sterile couple]. PMID- 6910879 TI - [Oligo-astheno-teratozoospermia]. PMID- 6910880 TI - [Azoospermia]. PMID- 6910881 TI - [Artificial insemination: technical aspects]. PMID- 6910882 TI - [Potential legislation of artificial insemination]. PMID- 6910883 TI - [What one should know about adoption]. PMID- 6910884 TI - [Professional-patient relations in the course of sterility]. PMID- 6910885 TI - [Letter to Matthew]. PMID- 6910886 TI - [Madame T.'s breast abscess]. PMID- 6910887 TI - [Clinical examination and self examination of the breast]. PMID- 6910888 TI - [Don't even neglect a breast anomaly]. PMID- 6910889 TI - [Radiologic studies of the breast]. PMID- 6910890 TI - [Benign mastopathies of the breast]. PMID- 6910891 TI - [Breast echography]. PMID- 6910892 TI - [Thermography in breast pathology]. PMID- 6910893 TI - [Cytology and needle biopsy in breast pathology]. PMID- 6910894 TI - [They say that nursing care does exist... but I haven't seen any of it]. PMID- 6910896 TI - [Rubella and pregnancy]. PMID- 6910895 TI - [Abscess of the breast]. PMID- 6910897 TI - [Toxoplasmosis and pregnancy]. PMID- 6910898 TI - [Listeriosis and pregnancy]. PMID- 6910899 TI - [Maternofetal infection: always serious for the fetus]. PMID- 6910901 TI - [Rupture of the fluid sac in Madame H]. PMID- 6910900 TI - [Attitude of the patient care team in a service for "high risk pregnancy"]. PMID- 6910902 TI - [Breast feeding in France constantly on the increase]. PMID- 6910903 TI - [Breast feeding today, a shared pleasure]. PMID- 6910904 TI - [Maternofetal infection. Fetal risk, clinical and paraclinical aspects]. PMID- 6910906 TI - [Nursing care process of a handicapped infant]. PMID- 6910905 TI - [Echography in obstetrics]. PMID- 6910907 TI - [Maternofetal infection. Urinary infections and pregnancy]. PMID- 6910909 TI - [Therapeutic indications in breast cancer]. PMID- 6910908 TI - [Streptococcal infections and pregnancy]. PMID- 6910911 TI - [Chemotherapy in breast cancer]. PMID- 6910910 TI - [Possibilities of radiotherapy in the local-regional treatment of breast cancer in 1981]. PMID- 6910913 TI - [Surgery in the treatment of breast cancer]. PMID- 6910912 TI - [Breast cancer: meticulous care and psychological support]. PMID- 6910914 TI - [Role of the circulating nurse in operations for breast tumors]. PMID- 6910915 TI - [Epidemiology of breast cancer]. PMID- 6910916 TI - [A concrete case of breast cancer based on the observations of a patient]. PMID- 6910917 TI - [Living like before]. PMID- 6910918 TI - [Waiting for the baby]. PMID- 6910919 TI - [Diagnosis of breast cancer]. PMID- 6910921 TI - [Anguish in psychiatry]. PMID- 6910920 TI - [Anguish and organic disease]. PMID- 6910922 TI - [Anguish in surgery]. PMID- 6910924 TI - [Insomnia and anxiety]. PMID- 6910923 TI - [Anguish and anxiety]. PMID- 6910925 TI - [Anguish and abandonment]. PMID- 6910926 TI - [Anguish and loneliness]. PMID- 6910927 TI - [Alcohol and anguish: apropos of a case report]. PMID- 6910928 TI - [Anxiety and personality tests]. PMID- 6910929 TI - [The caring function and anguish]. PMID- 6910930 TI - [The psychodysleptics]. PMID- 6910931 TI - [Adoption: some observations from the psychoanalytic and therapeutic viewpoint]. PMID- 6910932 TI - [Anguish and anxiety]. PMID- 6910933 TI - [Institutional psychotherapy and administration]. PMID- 6910934 TI - [Hierarchy, segregation, and institutional psychotherapy]. PMID- 6910935 TI - [What about institutional psychotherapy?]. PMID- 6910936 TI - [Illustration with case histories of the relationship between community psychiatry and institutional psychotherapy]. PMID- 6910937 TI - [Organization of therapeutic recreation in an institutional psychotherapy service]. PMID- 6910938 TI - [Packing and therapeutic club: Barbara's case history]. PMID- 6910939 TI - [Institutional psychotherapy from the children's aspect]. PMID- 6910940 TI - [Institutional psychotherapy and precariousness: dialogue]. PMID- 6910942 TI - The art and science of supervision: entitlements and obligation. PMID- 6910941 TI - [Role of the day hospital and conditions for admission]. PMID- 6910943 TI - Stress and the critical care nurse. PMID- 6910944 TI - Identities in nursing: a territorial issue. PMID- 6910945 TI - A mock drill can save a life. PMID- 6910946 TI - Performance evaluation of staff nurses. PMID- 6910947 TI - Objective management of attendance problems. PMID- 6910948 TI - Human relations management on a burn unit. PMID- 6910950 TI - Hospitalized patients work! PMID- 6910949 TI - Development of audit criteria for ambulatory nursing. PMID- 6910951 TI - Law for the nurse supervisor: nosocomial infections. PMID- 6910952 TI - Nursing's fifth column. PMID- 6910953 TI - [How does nursing education in the Scandinavian countries agree with nurses' function in the respective countries? 11. Education might in itself be cast totally wrong]. PMID- 6910954 TI - [How does nursing education in the Scandinavian countries agree with nurses' function in the respective countries? 12: The large institutions and specialties should first be demolished]. PMID- 6910955 TI - [Possible to experience class work as something positive]. PMID- 6910956 TI - [Child abuse and family orientation: important that we also discuss child's development and needs]. PMID- 6910957 TI - [Research of late results in surviving Argentinian torture victims: psychological harm most dominant after torture]. PMID- 6910958 TI - [Aabenraa community has recently established 24-hour home care]. PMID- 6910959 TI - [Keep an eye on the Committee for the Aged]. PMID- 6910960 TI - [How does nursing education in the Scandinavian countries agree with nurses' functions in the respective countries? 10. Necessary to have a change of direction in all educational programs]. PMID- 6910961 TI - [Blood kallikrein-kinin system in patients with coronary atherosclerosis]. PMID- 6910962 TI - Holistic nursing: what is it? PMID- 6910963 TI - American lifestyles put elderly at disadvantage. PMID- 6910964 TI - TNA testifies on education, presents BRC interim report. PMID- 6910965 TI - [Working as a health care teacher in laboratory assistants' education]. PMID- 6910966 TI - [Report on medical education at the University of Maastricht, Holland]. PMID- 6910967 TI - [Stress in children]. PMID- 6910968 TI - [Instruction in microbiology-hygiene, what good will it do?]. PMID- 6910969 TI - [Children's culture--everybody's business]. PMID- 6910971 TI - [Active evaluation]. PMID- 6910970 TI - [Language development. Situation with emigrants' children--rather a problem which emigrants' children encounter in Sweden]. PMID- 6910972 TI - [Terminal care--what do we know about it?]. PMID- 6910973 TI - [Progress work within a teachers' college]. PMID- 6910974 TI - The credentialing study. PMID- 6910975 TI - Questions and answers on Task Force on Credentialing in nursing. PMID- 6910976 TI - Guest editorial: medication administration by unlicensed personnel. PMID- 6910977 TI - The OR in the big city. Interview by Ann Caputo. PMID- 6910979 TI - Milk fever control. PMID- 6910978 TI - Certain characteristics of Corynebacterium pyogenes infection. AB - Isolation, characterisation and antibiotic sensitivity of 18 strains of Corynebacterium pyogenes from different animals have been reported. All the C pyogenes isolates uniformly differed from the typical strains of this species by the utilisation of trehalose and their failure to acidify maltose. The majority of the strains failed to grow in the presence of 0.1 per cent potassium tellurite. Tuberculosis-like lung lesion in a seven-day-old calf yielded one of the strains of C pyogenes. Histopathological changes in the calf lung have also been described. PMID- 6910980 TI - Antibiotic sensitivity pattern of recent clinical isolates of Streptococcus pneumoniae. AB - Antimicrobial susceptibility of 180 recent isolates of Streptococcus pneumoniae was determined by microdilution technic. There was a high degree of susceptibility to both penicillin G and cefuroxime, except for one strain which required 0.25 microgram/ml. All strains were inhibited by 0.06 microgram/ml of ampicillin, clindamycin and erythromycin. When tested against doxycycline 97.2% of the strains were inhibited by 1.0 microgram/ml. 8 microgram/ml inhibited all strains. Three of the strains were chloramphenicol-resistant with MIC more than 8 microgram/ml. These strains could be shown to inactivate chloramphenicol. All strains but three were susceptible to 20/l microgram/ml of sulfamethoxazole/trimethoprim. PMID- 6910981 TI - Scuba diving hazards: emergency management. PMID- 6910982 TI - Scuba diving hazards: health counseling. PMID- 6910984 TI - Dealing with feelings: coping with lethargy. PMID- 6910983 TI - Fiberoptic bronchoscopy. PMID- 6910985 TI - Oral hygiene for the elderly. PMID- 6910986 TI - Coping with quadriplegia. PMID- 6910987 TI - Otitis media: a common childhood infection. PMID- 6910988 TI - Diagnosis of middle ear effusion and infection. PMID- 6910989 TI - Malignant hyperpyrexia. PMID- 6910990 TI - A physician speaks out on nurses' burnout. PMID- 6910991 TI - Professional identity crisis--is nursing finally growing up? PMID- 6910992 TI - Encouragement counts in breast feeding. PMID- 6910993 TI - Programmed instruction: mental status assessment. PMID- 6910994 TI - Over-the-counter drug products. PMID- 6910995 TI - The legal side: treatment beyond death? PMID- 6910996 TI - Regional distribution of lysosomal enzymes in the retina and choroid of human eyes. AB - Regional distribution of lysosomal enzymes in the retina and choroid of human eyes was studied biochemically. Specific activities of acid phosphatase, cathepsin D, and arylsulfatase in the retina and choroid varied by area were also studied. The macular area showed the highest activities in comparison to other areas. PMID- 6910997 TI - The three-dimensional organization of lens fibers in the rabbit. A scanning electron microscopic reinvestigation. AB - The importance of the present reinvestigation of the three-dimensional structure of lens fibers in the rabbit is that it has shown the presence of all types of membrane specializations described before in one single lens of one species, the restricted distribution of some specializations, and the conformational changes within one fiber. Interlocking protrusions are present throughout the whole lens and must be considered as the main anchoring processes in the rabbit. Ball-and socket junctions are present in restricted regions and can be considered an additional anchoring processes. Undulations of the apical and lateral edges of the hexagonal fibers and folds and bends of the lateral surface have a limited distribution. It is postulated that they may play a role in lens changes during accommodation. PMID- 6910998 TI - [The strength of retinal sear tissue after argon-, xenon-, and cryocoagulation (author's transl)]. AB - A method is presented for measuring the adhesive force between retina and pigment epithelium in rabbit eye preparations. This force shows a great interindividual variation and so the absolute value is of little interest. The variation of several readings in one animal is, however, significantly smaller. Therefore the relative change in adhesive force between untreated and treated areas of one animal can be used. The data shows similar increases of +25-30%. For laser-, xenon-, and cryocoagulation, the maximum adhesive strength is reached within 4-8 days after treatment. After a few weeks the additional adhesion in treated areas slowly fell to about +10% as compared to pretreatment levels. PMID- 6910999 TI - 3H-thymidine autoradiography of guinea pig cornea and skin after exposure to solar simulating radiation. AB - In vitro autoradiography with tritiated thymidine was performed in guinea pig cornea and guinea pig skin after in vitro exposure to solar simulating radiation (UVB). UVA-irradiated and unirradiated specimens served as controls. Sparsely labelled nuclei, indicating the unscheduled thymine dimer repair DNA-synthesis (dark repair), were observed immediately after UVB exposure in the epidermis and upper dermis of the skin and in all cellular compartments of the cornea. Control samples did not exhibit dark repair. The ratio of sparsely labelled cells was similar in the epidermis and in the corneal epithelium, but was significantly higher in the corneal stroma and highest in the endothelium. PMID- 6911000 TI - [Retinoscopy under cycloplegic and non-cycloplegic conditions in children comparison of measurements of three examiners (author's transl)]. AB - The refractive status of 100 eyes were measured by three ophthalmologists utilizing retinoscopy under non-cycloplegic and cycloplegic conditions. The statistical analysis of the results was done by multiple regression. The retinoscopic measurements of sphere and cylinder of the three examiners show smaller differences under cycloplegic than under non-cycloplegic conditions. The largest differences in the measurements of axis were found in cases of small cylinder power. Especially in children and in patients with strabismus, the authors feel that measurements of the refractive state have to be carried out under cycloplegia. PMID- 6911001 TI - Freeze-fractured replica of Schlemm's canal and the trabecular meshwork in the primate. AB - Using a freeze-fracture technique, the fine structure of the Schlemm's canal and trabecular meshwork in the monkey was studied with special reference to intercellular junctions. Gap junctions were observed between the endothelial cells of Schlemm's canal and between the trabecular meshwork cells. Maculae occludentes were rarely observed between the endothelial cells of the inner wall of Schlemm's canal. The trabecular meshwork cells appeared to act in an electrotonic and metabolic syncytium. PMID- 6911002 TI - Ocular findings in leprous patients. A report of a survey in Malunga/Nepal. AB - A total of 116 patients in Nepal with advanced leprosy were examined in an ophthalmological survey. All patients were older than 20 years and none had suffered from leprosy for less than 10 years. Abnormal ocular findings occurred in 69.8% of all patients and 9.3% of the eyes were blind. The results are compared with those of other authors. PMID- 6911003 TI - In vivo and in vitro measurements of P32-uptake in the ocular tissue in cases of malignant melanoma. AB - In vivo and in vitro measurements of radioactive phosphorus uptake after intravenous injection of P32 in 26 cases of malignant melanoma of the choroid is reported. The specific radioactivity of dissected ocular tissue after enucleation is described. No statistically significant relationship between the radioactive phosphorus uptake and the histologically differentiated cell type was found. It was possible to demonstrate the P32 uptake as a function of the mass of the tumor. PMID- 6911004 TI - Transvitreal channel related to an intravitreal developmental anomaly. Slitlamp and electron-microscopical study. AB - Description of an intravitreal glia particle connected to an atypical transvitreal channel, which was found incidentally during the autopsy of an unfixed sheep vitreous. The anomaly is interpreted as an avulsion of retinal tissue during prenatal development, resulting in a decreased density of the vitreous framework (transvitreal channel) above the retinal defect. In analogy to other observations of transvitreal channels, which occur at all sites where the inner retinal surface is altered, the analysis of the anomaly sustains the hypothesis that framework of the vitreous is formed by elements of the retinal surface. The cells within the particle were examined with electronmicroscopy. They show immature collagen fibrils between glia cells, which may be precursors of vitreous collagen, immigrating through intercellular lacunae into the vitreous. PMID- 6911005 TI - Congenital retinal fold as a sign of dominant exudative vitreoretinopathy. AB - Four eyes of three patients from two large families with dominant exudative vitreoretinopathy showed an elevated retinal fold extending from the posterior pole toward the inferotemporal periphery of the fundus. A congenital retinal fold (ablatio falciformis congenita) has to be considered as a sign rather than a diagnosis, and can be caused by a few underlying disorders, to which dominant exudative vitreoretinopathy can be added. There are no indications that the hyaloid system is involved in the pathogenesis of a retinal fold in the latter condition. The formation of a retinal fold in dominant exudative vitreoretinopathy is the consequence of a developmental disorder of retinal vasculature during the last few months of intrauterine life, and may even occur after birth. The clinical picture and familial occurrence of many cases of congenital retinal fold described in the literature are suggestive of dominant exudative vitreoretinopathy, which only recently has been recognized as being a rather common condition. PMID- 6911007 TI - Representing nurses called a priority. PMID- 6911008 TI - 6,200 nurses attend ICN Congress. PMID- 6911006 TI - [A new classification scheme of non-proliferative diabetic retinopathy (author's transl)]. AB - The correlation of the topography of certain areas of the fundus, which exhibit relentless progression of microangiopathy (within the framework of general fluctuations in the course of the disease), as well as the degree of predominance of capillary perfusion and permeability disturbances in these respective areas justifies a classification of non-proliferative diabetic retinopathy into three distinct types: (1) pre-maculopathy/maculopathy in non-proliferative diabetic retinopathy (DR), (2) nonproliferative DR, and (3) non-proliferative DR lacking a tendency towards vasoproliferation or maculopathy. These results are based on regular biannual angiographic examinations of six different standard fundus areas in a total of 365 patients with non-proliferative DR. This scheme of classification has prognostic as well as therapeutic consequences. PMID- 6911009 TI - 'Nurse, where are you?' TV show gets high marks. PMID- 6911010 TI - Nurse wins disputed seat on hospital Board. PMID- 6911011 TI - Nurse is humanist in residence for terminal patients. PMID- 6911012 TI - New Hampshire loses Board as Nursing Practice Act expires. PMID- 6911013 TI - Breast-feeding is best for U.S. babies too. PMID- 6911014 TI - As I see it; bounties can't hide it: system swallows nurses. PMID- 6911015 TI - The moderation of elastase-induced emphysema in the hamster by intratracheal pretreatment or post-treatment with succinyl alanyl alanyl prolyl valine chloromethyl ketone. AB - The capacity of the synthetic elastase inhibitor, succinyl alanyl alanyl prolyl valine chloromethyl ketone (CMK), to moderate elastase-induced emphysema in hamsters was examined using morphometric and physiologic measurements. When 0.5 mg of CMK in saline was injected intratracheally 1 h before the intratracheal injection of 0.1 mg of porcine pancreatic elastase, the hamsters did not develop emphysema. When CMK was injected intratracheally 1 h after elastase, the severity of emphysema was reduced by approximately 50% compared with control animals receiving saline 1 h after elastase. The CMK was ineffective when administered intratracheally 4 h after elastase. PMID- 6911017 TI - AORN education: you can develop your own modules for self-instruction. PMID- 6911018 TI - Certification a force of planned change in nursing practice. PMID- 6911016 TI - Nosocomial staphylococcal infections. PMID- 6911019 TI - 'Direct supervision' has only one meaning in the operating room. PMID- 6911020 TI - Simplified surgery for varicose veins. PMID- 6911022 TI - Concerns continue over staff exposure to OR waste gases. PMID- 6911021 TI - Necrotizing enterocolitis in premature infants. PMID- 6911023 TI - A teaching plan for Nissen fundoplication. PMID- 6911025 TI - An unexpected visit beyond the Great Wall. PMID- 6911024 TI - Funding for nursing research. PMID- 6911026 TI - On-the-job problems require communication, flexible leadership. PMID- 6911027 TI - Effects of orthovanadate on salt and water effluxes from the gills of seawater eels, Anguilla anguilla. AB - Orthovanadate (5 . 10(-7) M) perfused through isolated gills at a constant rate increased the perfusion pressure by 40% but inhibited the effluxes of Na+ and Cl- by 40%. Water efflux was unaltered. Ouabain (10(-4) M) and rotenone (10(-4) M) influenced salt and water effluxes in the same way but did not alter perfusion pressures. Orthovanadate (10(-5) M) perfused at constant rate increased the pressure nearly 2.5-fold; under these conditions effluxes of Na+, Cl- and H2O were all increased approximately 2.5-fold. PMID- 6911028 TI - [Method of determining human and animal plasma kallikrein inhibitors]. AB - A method for determining blood plasma kallikrein inhibitors is suggested. It is based on inhibiting the kininogenase activity of kallikrein. The donors' dry plasma devoid of kininases, of other proteolytic enzymes and their inhibitors was used as source and reference of prekallikrein, kallikrein and high-molecular kininogen. Freshly centrifuged plasma was incubated in the presence of unithiol at 37 degrees C in amounts producing a 30-50% inhibition of the kininogenase activity of kallikrein. The values obtained reflected the activity of kallikrein inhibitors and might be of great importance in the study of the physiological role and biochemical properties of kallikrein inhibitors in different animal species, in the diagnosis and prediction of various diseases, as criterion for laboratory control over administering tissue inhibitors of proteolytic enzymes of animal origin. PMID- 6911029 TI - Catha edulis (khat): some introductory remarks. PMID- 6911030 TI - The cathedulin alkaloids. AB - Studies on fresh and dried leaf and shoot material of Catha edulis (khat) collected in Ethiopia, Kenya and the Yemen Arab Republic have led to the isolation, separation and characterization of new celastraceous alkaloids, the cathedulins, with molecular weights in the 600-1,200 range. All the cathedulins whose structures have been investigated prove to be polyesters or lactones of a sesquiterpene polyol core and fall into three groups: (a) low molecular weight esters of pentahydroxydihydroagarofuran; (b) cathedulins of medium molecular weight characterized by the possession of a euonyminol core and an evonimic acid dilactone bridge; and (c) high molecular weight, more complex esters of euonyminol. Chemical evidence and spectral data were used in assigning structures to the cathedulins studied as well as in placing the various esterifying acids on the different hydroxyl positions of the sesquiterpene core. In addition to cathedulins, neutral products isolated from khat include beta-sitosterol and its glycoside, friedeline, and hydroxylated delta 4-exo-relatives of the latter. Moreover, the pigmented root-bark contains triterpenoid quinones including celastrol, pristimerin, iguesterin and tingenone (tingenin A and B). PMID- 6911031 TI - The chemistry of khat. AB - This paper presents a review of literature on the chemical composition of khat (Catha edulis Forsk., Celastraceae). The effect of chewing fresh khat could not be explained satisfactorily by the action of d-norpseudoephedrine which was, for a long time, believed to be the only stimulant in khat. A comprehensive study on the chemical composition of khat was undertaken at the United Nations narcotics Laboratory with the aim of isolating and characterizing the principles of the fresh plant active on the central nervous system. This work resulted in the detection and isolation of cathinone, a phenylalkylamine characterized as (-) alpha-aminopropiophenone. It is the main phenylalkylamine component of fresh khat, and pharmacological studies indicate that it may be the compound responsible for the characteristic stimulant activity and abuse potential of the plant. Some of its "decomposition" or transformation products, such as norpseudoephedrine, norephedrine, 3,6-dimethyl-2,5-diphenylpyrazine, and 1-phenyl 1,2-propanedione, have also been isolated and characterized. PMID- 6911032 TI - Khat: pharmacognostical aspects. AB - A survey was made of the early literature on the production of khat. A botanical and micromorphological examination of 15 samples of Catha edulis was carried out and the findings were compared with data from the earlier literature on the subject. Based on earlier and present observations, the vital organs (leaves, flowers, fruit and seeds) are described, with illustrations, to assist in the identification of khat. PMID- 6911033 TI - Conclusions and recommendations of the Expert Group on the Botany and Chemistry of Khat. PMID- 6911034 TI - Behavioural effects of cathinone, an amine obtained from Catha edulis Forsk.: comparisons with amphetamine, norpseudoephedrine, apomorphine and nomifensine. AB - The effect of khat (Catha edulis Forsk., family Celastraceae), a plant used for its stimulant effects in eastern Africa and southern Arabia, has until recently been attributed to the pharmacological action of d-norpseudoephedrine, also known as cathine. The isolation in 1975 of cathinone revived an earlier suggestion that the fresh leaves contained a substance more potent than cathine. The pharmacological assays reported on in this paper appear to confirm the higher stimulant capacity of cathinone. This substance produces qualitatively similar locomotor stimulation in mice and comparable stereotypy in rats as amphetamine does, although it is approximately half as active. The results obtained after pre treatment with reserpine or alpha-methyl-p-tyrosine, which interfere with the catecholamine system, strongly suggest that cathinone interacts with brain catecholamines by an indirect mechanism and, most probably, by affecting neurotransmitter release of the labile pool. PMID- 6911035 TI - Educational mobility: more RNs needed in baccalaureate programs. PMID- 6911036 TI - Pressure sores: distinguishing fact from fiction. PMID- 6911037 TI - 16 steps to better decubitus ulcer care. PMID- 6911038 TI - Care planning a comment on the Canadian experience. PMID- 6911039 TI - Cuddlers: a volunteer infant stimulation program. PMID- 6911040 TI - Nurse do you hear me? PMID- 6911041 TI - Before it's too late... PMID- 6911042 TI - How do you stay so slim? PMID- 6911043 TI - Epidemic: what to do before a mass immunization program. PMID- 6911044 TI - When minutes count-helping your MI patient know when to get the help he needs. PMID- 6911045 TI - Intravenous containers--variability in measurement. PMID- 6911046 TI - Helpful hints on how to read a plastic I.V. container. PMID- 6911048 TI - Inroads in consumer participation. PMID- 6911047 TI - CNA's standards for nursing practice: an interpretation. PMID- 6911049 TI - No time to quit! PMID- 6911050 TI - For nurses only: the professional responsibility clause in the Ontario nursing contracts. PMID- 6911051 TI - Comparison of the rate of aminoacylation of tRNA isolated from NMRI mouse liver with tRNA isolated from Krebs II ascites or mouse plasmacytoma cells. AB - A comparison of the initial rates of aminoacylation of tRNAs isolated from different sources for 17 amino acids was performed. tRNA was isolated from NMRI mouse liver (tRNA L) and from Krebs II ascites tumors (tRNA Asc), and aminoacyl tRNA synthetases were prepared from the latter cells. The aminoacylation of tRNA Asc was 31-88% slower than the charging of tRNA L. In similar studies, tRNA from a mouse plasmacytoma tumor (tRNA Mt) and from suspension cultured cells of the same cell line (tRNA M) were compared to tRNA L in the aminoacylation reaction catalysed by synthetases isolated from tumor or suspension cultured cells. About half of the tRNAs (Mt or M) for the 17 amino acids tested differed in charging rate when compared to tRNA L, but the differences were not as great as those observed in the experiments where tRNA Asc and tRNA L were compared. PMID- 6911052 TI - Comparison of the codon recognition properties and of the utilization of normal and tumor specific Phe-tRNAs in protein synthesis. AB - Phe-tRNA from normal rat liver (designated Phe-tRNAN) and the under-modified, tumor specific, Phe-tRNAs from mouse neuroblastoma (designated Phe-tRNANB) and rat lymphoma (designated Phe-tRNARL) recognize the phenylalanine codons, UUU and UUC in a ribosome binding assay, but not other codons that differ from UUU and UUC in a single base at either the 5' or 3' position. Phe-tRNANB was incorporated into protein more extensively than either Phe-tRNARL or Phe-tRNAN in wheat germ extracts programmed with globin mRNA. The utilization level of each Phe-tRNA was correlated with its rate of deacylation in wheat germ extracts, i.e., Phe-tRNANB deacylated less rapidly than Phe-tRNARL or Phe-tRNAN. Phe-tRNA, from which the Y base was chemically excised (designated Phe-tRNA-Y), did not respond to UUU or UUC in the ribosomal binding assay, nor did it transfer its phenylalanine to protein in wheat germ extracts programmed with globin mRNA. PMID- 6911053 TI - A good death. PMID- 6911054 TI - Nursing assessment of the ambulatory patient with brain metastases. PMID- 6911055 TI - Implementation of one standard of care in a variety of patient care agencies. PMID- 6911056 TI - Hypercalcemia of malignancy. PMID- 6911057 TI - Technical and psychological problems and concerns arising from the outpatient treatment of cancer with direct intraarterial infusion. PMID- 6911058 TI - Chemotherapy: helping patients to know the drugs they are receiving and their possible side effects. PMID- 6911060 TI - Cancer nursing and the law: emotional injuries. Part III. PMID- 6911059 TI - Tamoxifen: a brief review. PMID- 6911061 TI - Programmed instruction: cancer care. Leukemia: the acute and chronic leukemias. PMID- 6911062 TI - Nursing care of the patient with chronic occlusive peripheral artery disease. PMID- 6911063 TI - Permeabilization of Ehrlich ascites tumor cells by human serum. PMID- 6911065 TI - [The role of women and nursing--a lesson from folk medicine. (2)]. PMID- 6911066 TI - [Interpretation of Louis Bower's "Nursing Plan Process"--a systemic approach in nursing and a nursing model]. PMID- 6911064 TI - Dexamethasone, aldosterone and kallikrein release by isolated rat kidney. AB - 1. The effect of D-aldosterone and dexamethasone on kallikrein release was studied in the isolated rat kidney perfused with modified Krebs-Henseleit buffer. 2. Animals received D-aldosterone or dexamethasone (10 microgram/100 g body weight) daily for 3 days. Their isolated kidneys were then perfused with the same steroids at rates of 2.0-2.5 microgram/min for 30 min. 3. Dexamethasone increased kallikrein release significantly (P less than 0.001) both in urine and in venous outflow. 4. D-Aldosterone had no significant effect on kallikrein release, either in urine or in venous outflow. PMID- 6911067 TI - [Nursing audit--a definition]. PMID- 6911068 TI - [Regional health care activities in Nepal--activities in the past 20 years and future prospects]. PMID- 6911069 TI - [A patient with exaggerated illusions]. PMID- 6911070 TI - Midwifery: breath of life. PMID- 6911071 TI - Chat sheet (community health nursing). PMID- 6911072 TI - I chose a midwife. PMID- 6911073 TI - Adhesion and microorganism pathogenicity. PMID- 6911074 TI - Plasmodial modifications of erythrocyte surfaces. AB - The maturation of malarial parasites in red blood cells produces major alterations in the composition and properties of the host cell surfaces. Existing surface-exposed proteins are modified and new antigenic glycoproteins are synthesized by the parasite and inserted into the membrane. Some of the neoproteins are associated with surface excrescences on the host cells and in some cases these foster adhesion of those cells to capillary endothelium. The erythrocyte endoskeleton is degraded and in association the infected cells become deformed and lose pliability. An increase in intracellular Ca2+ may contribute to the changes in host cells surfaces. PMID- 6911075 TI - Interaction of chlamydiae with host cells and mucous surfaces. AB - For chlamydiae, as obligate intracellular parasites, attachment to and ingestion by host cells are essential steps in reproduction. Their attachment site appears to be heat-sensitive; it has not been correlated with any morphological entity. Antibody blocks chlamydial attachment to cells and, for certain chlamydia psittaci and chlamydia trachomatis strains which are highly infective for cell cultures, N-acetylglucosamine appears to contribute to cell receptor specificity. Sialic acid residues have been suggested as receptors for other C. trachomatis strains. The guinea-pig inclusion conjunctivitis strain of C. psittaci becomes associated with the conjunctiva during incubation of inoculated tissue fragments in vitro. However, although antibody from tears neutralizes infectivity of this strain in vivo, association of the organism with tissue fragments is not inhibited, suggesting that antibody neutralization in vivo is not mediated by prevention of attachment to cells. Chlamydial infectivity for cell monolayers is greatly increased by centrifugation. The process is temperature-dependent and involves cooperative interactions between direction force and the pressure generated during centrifugation. Enhanced infectivity appears to result from changes induced in the cell surface. These changes may favour nonspecific interactions in attachment, since antibody inhibition of infectivity on static cell monolayers is overcome by centrifugation. PMID- 6911076 TI - Functions of surface glycoproteins of myxoviruses and paramyxoviruses and their inhibition. AB - Two glycoproteins, HN and F, are present on the surface of paramyxoviruses. HN has receptor-binding amd neuraminidase activities. F is involved in viral penetration, cell fusion and haemolysis and is activated by proteolytic cleavage by a host enzyme into two disulphide-bonded subunits (f1 and F2). The ability of the virus to initiate infection and undergo multiple cycle replication depends on the presence of an activating protease in the host; thus cleavage of F is a major determinant of pathogenesis. The new N-terminus generated on F1 by cleavage is involved in biological activity, and the amino acid sequence of this region of F1 by cleavage is involved in biological activity, and the amino acid sequence of this region of F1 is hydrophobic and highly conserved among para-myxoviruses. In an attempt to design specific inhibitors, oligopeptides and analogous to this region were synthesized and found to be highly active, specific inhibitors of viral penetration, cell fusion and haemolysis. Inhibition is amino-acid-sequence specific and affected by peptide length, steric configuration and addition of groups to the n-terminal and C-terminal amino acids. Replication of influenza virus was also specifically inhibited by oligopeptides resembling the N-terminus of the HA2 polypeptide. Like that of F1 protein the N-terminus of HA2 is generated by a proteolytic cleavage that activates infectivity. These results have provided information on the action of proteins in viral penetration and membrane fusion and they suggest a possible new approach to chemical inhibition of viral replication. Studies with specific antibodies to each of the paramyxovirus glycoproteins have shown that antibodies to the F protein are essential for effective prevention of the spread of infection. Antibodies to the HN protein, although capable of neutralizing released virus, do not prevent spread to adjacent cells through membrane fusion mediated by the F protein. These findings have implications for the design of effective vaccines against paramyxoviruses and also provided additional insight into the mechanisms involved in the atypical and severe infections observed in individuals who received inactivated paramyxovirus vaccines and were later infected. PMID- 6911077 TI - An in vivo model for studying adherence of intestinal pathogens. AB - A new method for preparing an isolated colonic loop in a living rabbit is described. The loop with its intact neurovascular supply can be used as as a "living test tube" to study the adherence of microorganisms to intestinal mucosa. Moreover, the clear colonic mucus produced by the loop can be used to study its physiochemical nature and protecting properties in health and disease. PMID- 6911078 TI - [Integrated education and student-teacher relations]. PMID- 6911079 TI - [Nursing and urological endoscopy]. PMID- 6911080 TI - [Actualization of the introduction to the principles of integrated nursing and integrated education in our institution]. PMID- 6911081 TI - [Integrated nursing as seen from the patient-nurse viewpoint]. PMID- 6911082 TI - [The urological patient in the operating room]. PMID- 6911083 TI - The nurse of the future. PMID- 6911084 TI - [The influence of the urethral pressure profile on the prognosis of incontinence surgery (author's transl)]. AB - In 114 out of 1215 stress-incontinent women the maximal urethral closure pressure was determined. Descensus of urinary bladder and urethra was proved by lateral urethrocystography. In the group of sphincter weakness (Edwards) which was to be found in 46 patients, only 48% became continent after colporrhaphy, Marshall Marchetti-Krantz or sling surgery. If the pressure profile was found to be normal 74% of our patients felt cured after incontinence-operation. Sphincter weakness determines a failure due to surgery which is statistically of significance (P less than 0,01). PMID- 6911085 TI - [Results of the operative treatment of severe second degree stress incontinence in 425 cases (author's transl)]. AB - The results of the operative treatment of 425 women with severe stress incontinence grade II and grade III according to Ingelman-Sundberg are reported. The following types of operation were used: diaphragmaplasty (DP), urethrovesicosuspension Marshall-Marchetti-Krauz (MK), lyoduraslings (LDS), and puborectalisplasty of Franz-Ingelman-Sundberg (PRP). The choice of the operative method and the evaluation of the results of the operation were done by history, clinical examination and radiological examination. The urodynamic investigation with a microtransducer which we used since 1977 prior and after each operation for stress incontinence does have little influence on the choice of the operation. The value of urodynamic studies on a quantitative evaluation of the type of operation is at present doubtful. Our definitive evaluation of the result of the operation was done not earlier than one year following the operation in a prospective stress incontinence clinic. Because of our individual treatment plan from the onset by different methods 89% of the 425 patients were cured or markedly improved. PMID- 6911086 TI - [Cytological and colposcopic diagnosis of decidual ectopy of the cervix (author's transl)]. AB - The cytological and colposcopic fundamentals for correct diagnosis have been compiled in this article on the basis of 86 cases with residual transformation of the cervix. Colposcopically, the decidual transformation of the portio was subdivided into 4 groups, and the colposcopic characteristics of ectopia decidualis were defined. For cytological clarification of decidual transformation of the cervix, two smears are required. The first, taken from the lateral vault of the vagina, enables an insight into the hormonal functioning of the vaginal mucosa. The second smear is prepared by scraping off the transformed tissue. The smear also contains cells from the lower stratum. These are the decidually transformed stroma cells. Evaluation of these preparations and final diagnosis should be effected by an experienced and skilled cytologist. Colposcopic cytological examination can supply sufficient diagnostic material to eliminate the need for biopsy for the purpose of histological examination. This has been tested in 21 cases of decidual ectopy. PMID- 6911087 TI - [Endolymphatic stromal myosis, a rare semimalignant tumour (author's transl)]. AB - The rarely occurring disease of endolymphatic stromal myosis is discussed by means of an impressive case. The cells of this semimalignant tumour resemble those of the endometrium, but it is not clear whether this tumour can be derived histogenetically from the endometrium or from the cells of the duct of Muller (ductus paramesonephricus) or from pericytal cells. The histological pattern of the tumour, which is characterized by the uniformity of small spindle-like oval cells without remarkable mitotic activity, and by a lack of atypical criteria, does not permit any prognosis in respect of its clinical behaviour. According to the rare references in literature, the clinical course is usually protracted with occasional occurrence of metastases and relapses. The therapy consists of radiotherapy and administration of progesterone. The case described in this article is a clinically malignant one because of disseminated metastases and relapse following initially successful therapy. PMID- 6911088 TI - [Human in vitro fertilisation and embryotransfer: first results at the 2nd department of obstetrics and gynaecology, university of vienna (author's transl)]. AB - Methods and Results of human in vitro fertilisation at the 2nd Department of Obstetrics and Gynaecology, University of Vienna are reported. Applying preparations of media and culture techniques according to Edwards et al. no satisfactory results could be achieved: only 3 out of 11 preovulatory oocytes were fertilised, no cleavages occurred. Using modified Ham's F 10 medium according to Lopata et al. fertilisation could be observed in 60% as well as regular cleavages in 40%. 5 Embryotransfers have been performed in the 8 cell or in the 16 cell stage respectively. No implantation occurred in 4 of these, in one case evidence for a transient implantation could be proved by an increased activity of SP1 and HCG beta. In this case obviously postimplantation death occurred resulting in a bleeding 16 days after oocyte recovery. Possible reasons for failures in fertilisation and cleavage as well as possibilities for improving the rate of reimplantation are discussed. PMID- 6911089 TI - [Advanced ectopic pregnancy including combined ectopic and intra-uterine pregnancy (author's transl)]. PMID- 6911090 TI - [Ranking of hysterosalpingography (HSG) in the physician's consultation-room practice concerning sterility problems (author's transl)]. AB - In the following up of the diagnosis of the female sterility we practised 123 hysterosalpingographies (HSG) from 1972--1978. Presupposition was the proof of the ovulation by base temperature. The HSG is the beginning of the diagnosis to recognize the intracanalicular changes of the uterus and to avoid senseless treatment with hormones. 34.9% of the patients showed absolutely normal uteri or tubes. Pathological results were be found in 17.7% by the uterus and 47.4% by the tubes. Without any treatment we have had a success of pregnancy after HSG in 26.8%. Further pregnancies we got by operative intervention or medicamentous treatment in only 4,8%. 23 patients = 18,7% could not be evaluated because they were missing. The HSG is an important and supplementary method for a diagnosis of the female sterility and it does not compete with the method of the useful pelviscopy. PMID- 6911091 TI - [Ultrasonic diagnosis in cervical pregnancy (author's transl)]. AB - The cervical pregnancies are most times complicated by severe uterine haemorrhages which can be stopped generally only by hysterectomy. Ultrasonic diagnosis provides new possibilities in diagnosing this dangerous localization of pregnancy prior to the onset of clinical symptoms. The characteristic sonographic findings of two cases are discussed: one early and one advanced case, both were symptomless. Although in rare cases a delivery at term could be observed, the termination of pregnancy seems to be indicated in cases of a doubtless ultrasonic diagnosis. PMID- 6911092 TI - [Pregnancy and parturition in idiopathic thrombocytopenic purpura (author's transl)]. AB - The article reports on the case of a 39-year old primipara with severe idiopathic thrombocytopenic purpura (ITP). The patient, who did not respond to corticosteroids, gave birth to a healthy child after thrombocyte substitution, parturition being effected by means of Caesarean section. The article discusses pathogenesis, prognosis and the therapeutic aspects of corticosteroid treatment, platelet substitution, splenectomy and mode of delivery. PMID- 6911093 TI - [Spontaneous rupture of an uterine vein during pregnancy. A case report (author's transl)]. AB - The rare case of a spontaneous rupture of the uterine vein is reported. The diagnosis and the etiology are discussed from a review of the literature and the report of a new case. The case is reported to alert to the possibility of rupture of an uterine vein when acute abdominal symptoms and signs are found during pregnancy and present diagnostic problems of an unclear nature. Early laparotomy is necessary to improve the treatment of the haemorrhagic shock and the maternal mortality. In most cases of antepartum of intrapartum rupture of the uterine vein a Caesarean section and suture ligation of the ruptured vein is adequate treatment. Without prior knowledge of this syndrome a Caesarean hysterectomy was performed in our case. PMID- 6911094 TI - [Heart diseases and pregnancy (author's transl)]. PMID- 6911095 TI - Nutrition: fractures and diet--what's the relationship? PMID- 6911097 TI - Cooperative care: patient, partners, and professionals. PMID- 6911096 TI - Legislators on the Mall, who's the neediest group of all? PMID- 6911098 TI - How to improve the first stage of digestion. PMID- 6911099 TI - It was easier, but... PMID- 6911100 TI - Identity awareness as a holistic approach to self-healing. PMID- 6911101 TI - Hypothermia in the elderly. PMID- 6911102 TI - Common concern: legal guardianship. PMID- 6911103 TI - Drugs and the elderly. When the patient has a potassium deficiency. PMID- 6911104 TI - 70+ and strong. A World War I pilot revisits the airways by glider. PMID- 6911105 TI - Frontier Nursing Service: looking towards tomorrow. PMID- 6911107 TI - Clinical experience in Mound Bayou, Mississippi. PMID- 6911106 TI - Being a courier - four accounts of a courier's daily activities. PMID- 6911108 TI - Education and service: the Leslie County Health Careers Program. PMID- 6911109 TI - Respiratory care project. PMID- 6911110 TI - One step toward prevention. PMID- 6911112 TI - Breakthrough to nursing: retention is part of breakthrough, too. PMID- 6911113 TI - Since the world revolves around you, why aren't you in charge? Some thoughts on self assessment. PMID- 6911111 TI - Take the first step; a legislative primer. PMID- 6911114 TI - Even "people helpers" need help--stress and addictive behaviour in nurses. PMID- 6911115 TI - Is life the pits? PMID- 6911116 TI - How to study and remember efficiently. PMID- 6911118 TI - My most unforgettable patient. PMID- 6911117 TI - Nursing's image. PMID- 6911119 TI - Self awareness. PMID- 6911120 TI - [A milligram of reflexion on medicines]. PMID- 6911121 TI - [Guillain Barre syndrome]. PMID- 6911122 TI - [Patient care planning for an elderly patient in a hospital]. PMID- 6911124 TI - [Freedom of choice... in continuing education]. PMID- 6911123 TI - [Children alone in the land of giants]. PMID- 6911125 TI - [The nurse and her "fool" or the limits of "mothering"]. PMID- 6911126 TI - [Before its too late...]. PMID- 6911127 TI - The HVA and key workers. PMID- 6911128 TI - Cot deaths--the current situation and the role of the health visitor today. PMID- 6911129 TI - Some psychological consequences of bereavement by sudden infant death syndrome. PMID- 6911131 TI - The dying child and professional withdrawal. PMID- 6911130 TI - Keep cool, baby: the risks of overheating in young babies. PMID- 6911132 TI - Help for the bereaved. PMID- 6911133 TI - A terminal care and bereavement counselling service. PMID- 6911134 TI - Care of the bereaved. PMID- 6911135 TI - What a shame. PMID- 6911136 TI - Foundation for the Study of Infant Deaths. PMID- 6911137 TI - Linkage disequilibria between HLA-B and the rarer properdin factor B alleles, BfF1 and BfS1. AB - Phenotypic association and highly significant linkage disequilibria have been demonstrated for HLA-B18 and BfF1 and HLA-Bw50 and BfS1 alleles among Caucasians from Australia and the United States (San Francisco Bay area). The HLA-B18, BfF1 association appears to be associated with HLA-Aw30. It is possible that BfS1 arose as a mutation, after the evolutionary splitting of HLA-Bw21, on an HLA-Bw50 haplotype, and that BfF1 arose on an HLA-Aw30, B18 haplotype. PMID- 6911138 TI - Smoking among new student nurses. AB - Smoking is very common among nurses. Various explanations have been offered for this but the reasons for it are still unclear. To investigate some aspects of this problem and prepare for a longitudinal study, an intake of students to a large nursing school was surveyed. Information was obtained on their smoking behaviour, social background and preconceptions of nursing. PMID- 6911139 TI - A comparison of mothers' concerns regarding the care-taking tasks of newborns with congenital heart disease before and after assuming their care. AB - This exploratory study sought to identify, during the newborn's hospitalization, mother's concerns regarding the care-taking tasks of their infants with congenital heart disease and to determine, 1 month subsequent to discharge, whether the mother's concerns had changed. The sample consisted of ten mothers of infants aged up to 2 months at the time of the first interview which was conducted in hospital. A second interview was conducted in the home of the subjects 1 month subsequent to discharge. The content of the responses to the interview questions was analysed and presented under the major headings of selected characteristics of the sample, developmental tasks of parenthood and selected maternal attributes. The largest number of concerns in both interviews related to the tasks of learning how to anticipate and to recognize the needs of the baby. A significant difference was found between the total number of concerns reported by each mother in the two interviews. There was an overall increase of 61%. Implications and recommendations are presented in light of the small non random sample. PMID- 6911140 TI - Interactions of mothers with their newborns in the first half-hour of life. AB - Eight first-time and eight second-time working class mothers were observed interacting with their newborn babies during the first half-hour of life. In all cases the father was present for at least some of this period. The interactions were notable for their passivity, mothers looked for long periods at their babies and engaged in some finger-tip touching of the babies face and head, but they engaged in very little exploration of the babies, few vocalizations and few expressive acts such as kissing. However, the presence of the father was associated with more intense mother-newborn interaction. First-time but not second-time fathers tended to be excluded from interaction with either the mother or the baby at this time. These results are discussed in the light of current thinking on mother-newborn bonding and the role of midwifery staff in promoting that bonding process. PMID- 6911141 TI - Pain assessment: development of a tool for the nurse and the patient. AB - The assessment of pain is a difficult and yet vital component of nursing care. Discrepancies in the nursing management of pain can result from inadequate data collection and personal biases about the pain experienced by the patient. For example, how often is the patient with chronic pain consulted about personal remedies used at home to facilitate pain relief? Do nurses have preconceived ideas of how much pain should exist with each disease entity? A tool was developed which incorporated many of the variables affecting the pain response in order to sensitize nurses to the need for careful pain assessment. The information in this tool was conveyed to both graduate and student nurses resulting in improved charting of the patient's pain and improvement in the ability to assess the patient in pain. Description of pain by the patient is often a frustrating experience and yet necessary in helping to determine the cause of the pain and the appropriate interventions. Patients often have difficulty describing their pain to health professionals. A ruler which includes the most frequently utilized terms to describe pain was developed, revised and tested on various patients. The patients interviewed found the tool easy to use and all felt they could communicate their sensation of pain to the nurse. PMID- 6911142 TI - Recording patients blood pressure: a review. AB - This paper reviews the proper technique which should be adopted by the nurse in order to obtain accurate blood pressure measurements. Although this is difficult using conventional instruments, statistics uniformly confirm the harmful significance of an elevated blood pressure. Any nurse delivery high quality care must be able to carry out nursing procedures skillfully and accurately. The methodology of blood pressure recording is discussed, analysed and evaluated. It is well-documented that there are many potential sources of error in recording blood pressure, including poor technique and observer bias. The paper deals with these and highlights some of the dilemmas that this technique presents to the nurse. A claim is made that many nurses are often inadequately trained in blood pressure measurement, and with increasing reliance on the nurse for records, much more attention need to be focused on this area. PMID- 6911143 TI - A phenomenological look at giving an injection. AB - Phenomenology attempts to get beyond the surface structure of experience to examine the underlying meaning of the realities of everyday life. In this paper, the writer attempts to answer the question, what is it live to give an injection? The paper is based on essays and interviews with ten experienced nurses, ten undergraduate nursing students and four diabetic patients who administered their own insulin. The author explores the meaning of the language used relating to an injection, the meaning that giving an injection has for the nurse, the feelings involved in preparing and giving the injection, and the meaning of the patient's response to the nurse. Two particular client groups create additional feelings for the nurse; the child and the unconscious patient. The phenomenologist never reaches a conclusion. The essay should challenge the reader to respond by saying, 'Yes, it is like this,' or 'No, I don't believe it is like that.' In responding, further understanding is developed. The aim of the author is to stimulate readers so they better understand the anxiety nursing students feel about giving an injection. PMID- 6911144 TI - The public health nurse as a guide in infant child-care and education. AB - The prime aim of the study was to develop the child-care and education guidance provided by public health nurses at health centres for parents of children aged 1 or 2. The research was partly carried out according to the principles of action research. The researcher's purpose was to influence the public health nurses' child-care and education guidance by designing measures and forms for the documentation and evaluation of the development, environment, and care practices of children aged 1 or 2. Methods were improved by the collaboration between the researcher and the nurses in the course of the research. In addition, the investigator designed a child-care and guidance programme for parents of such children. The premise of the public health nurse's action was the WHO's process model for nursing. The study focused on public health nurses and on children aged 1-2 and their parents. The overall action model of the public health nurses (needs assessment, goal-setting, implementation of action and evaluation) improved in the course of the experiment. The methods facilitated the implementation of action and provided it with clear objectives. The reliability and validity of the methods were reasonably high. The parents of the experimental group felt significantly more often then than those of the control group that they had obtained information about the development, care, and education of the child aged 1-2 from the public health nurses. The guidance had also helped the parents solve child rearing problems. The level of development in the children of the experimental group was higher than that of the control group at 24 months, in certain areas. PMID- 6911145 TI - Working women and breastfeeding in Israel. AB - Two-hundred and ninety-one working women in Israel were interviewed 7-9 months after childbirth. The mean number of months that they had breastfed was 2.03. The duration of breastfeeding increased with religiousity and higher education. Women born in Europe, primiparas and grandparas (4 + children) and those over the age of 40 breastfed longer. Most of the women returned to work only after completing breastfeeding. Duration of breastfeeding was reduced when the mother suffered from stress, tiredness, encountered feeding problems, or if the baby cried excessively. PMID- 6911146 TI - An investigation of distress and discontent in various types of nursing. AB - It has been claimed that nurses in intensive therapy units are prone to high levels of distress and discontent. A questionnaire was designed to assess nurses' reactions to intensive therapy work and thus provide an object check on these claims. Nurses from eight intensive therapy units in England took part in the survey together with comparison groups from two renal units, a medical ward and a surgical ward. High levels of job satisfaction were registered in all the intensive treatment units with very few nurses indicating distress or a wish to leave their job. Some features of the work did attract criticism though, in particular the large fluctuations in work load, the level and adequacy of support, and the sparse amount of feedback given to nurses by senior staff. Much the same pattern was recorded with the medical and surgical nurses, and from one of the renal units. The second renal unit was known to be in a state of crisis at the time and it was predicted that a high level of discontent would be registered there. This proved to be the case and was taken as conformation of the validity of the questionnaire, and also as giving insight into the psycho-social conditions which may foster distress in nurses. PMID- 6911147 TI - The process of ageing. AB - An increasing elderly population involves nurses with older people in a wide sphere of activities. It is essential that an understanding of ageing and its effects is included as part of the knowledge which to common to all nurses. The study of gerontology has intensified in recent years but an interest in the phenomenon of ageing can be traced back through the centuries. A number of theories about the causes of ageing have been put forward but the evidence in support of these is still inconclusive. Control of hte ageing process remains beyond mankind, but it is known that environmental and hereditary factors contribute to the rate of ageing. Knowledge about the effects of ageing is accumulating. The influence of ageing on the functions of the body can be measured. Most functions are reduced in efficiency and the lowered levels of performance have to be considered in their relation to the medical and nursing care of older people. Ageing also has psychological and social implications. Changes in behaviour patterns can occur as a result of the influence of ageing on personality, intellect and memory. There are also changes in the social circumstances of older people resulting from such factors as retirement and bereavement. The growing problem of an elderly population is stimulating increasing research into the causes and effects of ageing. PMID- 6911148 TI - Activated factor B (Bb) of the alternative pathway of complement activation cleaves and activates plasminogen. AB - Activated Factor B (Bb), the central serine esterase of the alternative pathway of complement activation, exhibits restricted substrate specificity in the complement system for C3 and C5. The results presented here indicate that Bb can cleave and activate plasminogen in an experimental system containing purified plasminogen and Bb; complement cellular intermediate bearing the Bb-enzyme; or cobra venom factor-stabilized Bb-enzyme (CVF,Bb). Cleavage of plasminogen by Factor Bb generated 2 disulfide-linked polypeptides with apparent m.w. of 64,000 and 25,000 to 32,000 (SDS-PAGE). Complement cellular intermediates containing the C3b, Bb-enzyme cleave 40 to 80% of 4.5 micrograms of 125I-labeled plasminogen during 30 min of incubation at 37 degrees C; native Factor B was inactive; and anti-Factor Blg inhibited by 100% the plasminogen cleavage mediated by complement cellular intermediates bearing the Bb-enzyme. Fibrinolytic activity was detected in plasminogen activator (PA) assays when purified plasminogen and 125I-labeled fibrin tubes were incubated with Bb, CVF, Bb, or complement cellular intermediates bearing the C3b,Bb-enzyme: 10 micrograms Bb released 40 to 65% of the 125I-fibrin released by 5 micrograms urokinase in 4 hr at 37 degrees C. Plasminogen activator activity of the C3b,Bb-enzyme was found to be regulated in serum. At dilutions of NHS 1:50, the PA-activity of 1.6 micrograms Bb was 100% inhibited, and at a 1:250 dilution, 50% inhibition was observed. This report describes a novel activity for the Bb-enzyme, which constitutes the C3/C5 convertase of the alternative pathway of complement activation. PMID- 6911149 TI - Activation of the fifth and sixth component of the complement system: similarities between C5b6 and C(56)a with respect to lytic enhancement by cell bound C3b or A2C, and species preferences of target cell. AB - Brief shift of purified C5 and C6 at 0 degrees C to pH 6.4, followed by immediate neutralization, results in the generation of a factor, designated C(56)a, that lyses erythrocytes together with C7, C8, and C9. We compared C(56)a and C5b6 generated by an alternative-pathway convertase, with regard to their action on different target cells. We found tht C(56)a is similar to C5b6 in the following properties: 1) Together with C7, C(56)a forms a stable intermediate on either sheep or guinea pig erythrocytes. 2) Membrane-bound C3b, or A2C incorporated in the membrane, enhances lysis by C(56)a-9, as well as lysis by C5b6-9. We also found that the lysis of EC(56)a7 or EC5b67 intermediates by C8 and C9 depends on the species of the erythrocytes and the species of C8 and C9. Thus, lysis of sheep erythrocytes is more efficient with guinea pig C8 and C9 than with human C8 and C9. In the case of guinea pig erythrocytes, this relationship is reversed, i.e., these cells lyse more efficiently when human C8 and C9 are used. Enhancement of lysis by membrane-bound C3b or A2C does not abrogate this species incompatibility pattern. PMID- 6911150 TI - Advertising by nurse-midwives: beyond content. PMID- 6911151 TI - Independent reimbursement from third-party payers to nurse-midwives. PMID- 6911152 TI - Nurse-midwifery practice: a descriptive study of prenatal care. PMID- 6911153 TI - An attitude survey of lay-midwives and nurse-midwives. PMID- 6911154 TI - The impetus toward home birth. PMID- 6911155 TI - Use of the certified nurse-midwife in the education of the lay-midwife. PMID- 6911156 TI - Recertification for competence. PMID- 6911157 TI - Counseling working mothers. PMID- 6911158 TI - Five years of experience with public relations at the local level. PMID- 6911159 TI - Midwifery in seven European countries--a surprising spectrum. Part I. PMID- 6911160 TI - Why research in midwifery? PMID- 6911161 TI - [Effect of elastase on platelet adhesiveness and platelet aggregation (author's transl)]. PMID- 6911162 TI - [Basis of the care in obstetrical emergencies]. PMID- 6911164 TI - [Handling of neonatal emergencies]. PMID- 6911163 TI - [Significance of monitoring and the therapeutic policies in obstetrical emergencies: the interpretation of vital signs]. PMID- 6911165 TI - [Monitoring, examination, special equipment, handling of drugs and the keypoints in neonatal emergencies]. PMID- 6911166 TI - [Impressions of travel in China]. PMID- 6911167 TI - [Survey of the nursing technics of student midwives; the analyses of a questionnaire and test results at the time of course admission]. PMID- 6911168 TI - [Letter from America. Fetal alcohol syndrome]. PMID- 6911169 TI - [My point of view: imprinting]. PMID- 6911170 TI - [Natural childbirth. A discussion]. PMID- 6911171 TI - [New definitions of midwifery actions]. PMID- 6911172 TI - [Mechanism of natural childbirth and labor pain]. PMID- 6911173 TI - [Goal of midwifery service--toward emphasis on the family]. PMID- 6911174 TI - [Natural childbirth with the help of a team composed of the physician, patient, husband, midwife, and friends]. PMID- 6911175 TI - [Assistance for breast-feeding mothers on an ambulatory basis--continued maternal and child care]. PMID- 6911176 TI - [The role of the midwives and the result of a follow-up study of genetic counseling]. PMID- 6911177 TI - [A letter from America. Life in America]. PMID- 6911178 TI - [Expectations on midwives: discussion]. PMID- 6911179 TI - [Evaluation of the plan for midwifery training, with special reference to the table for evaluation of midwifery technics]. PMID- 6911180 TI - [Current status of and problems in clinical midwifery training]. PMID- 6911181 TI - [Blood transfusion system used at a local hospital, section Gynecology]. PMID- 6911182 TI - [Individual health education of expectant patients at the ambulatory department of Kimitsu Central Hospital]. PMID- 6911183 TI - [The relationship between Okeya's method of breast massage and the volume of milk secretion]. PMID- 6911184 TI - [Letter from America. Mid-trimester amniocentesis]. PMID- 6911185 TI - [Update on IUDs]. PMID- 6911186 TI - [Counseling sexually active, very young adolescent girls]. PMID- 6911187 TI - [Childbirth in England]. PMID- 6911188 TI - [PAG (pelvic angiography) following surgical treatment of hydatidiform mole]. PMID- 6911189 TI - [Methods of conducting and reporting the results of research]. PMID- 6911190 TI - [Reflection on midwifery actions in the past 7 years]. PMID- 6911191 TI - [Determination of the size of the uterine fundus and its increase to predict SFD (small for date baby) and LFD (large for date baby) during pregnancy]. PMID- 6911192 TI - [Study on health instruction for puerperal patients following episiotomy--with special reference to the patient's apprehension concerning their sex life]. PMID- 6911193 TI - [Survey on the sex life during pregnancy]. PMID- 6911195 TI - [Survey on sexual activities during pregnancy--responses from husbands]. PMID- 6911194 TI - [Pregnant women and episiotomy]. PMID- 6911197 TI - [Letter from America: amniocentesis]. PMID- 6911196 TI - [Return to nature: the birth of human ecology--philosophy of Dr. Michele Odan]. PMID- 6911198 TI - [Comparative obstetrics of monkeys and man. 17. Sex and reproduction of primates. (VI)]. PMID- 6911199 TI - [Pregnancy and delivery after artificial heart valve replacement]. PMID- 6911201 TI - [Diagnostic technology for nursing care]. PMID- 6911200 TI - [Technics for medical history taking and interviews necessary in nursing]. PMID- 6911202 TI - [Methods and new viewpoints in nursing assessment]. PMID- 6911204 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The skin and skin appendages]. PMID- 6911203 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). General health conditions]. PMID- 6911205 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The head and neck areas]. PMID- 6911206 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The eye]. PMID- 6911207 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The ear and the nose]. PMID- 6911208 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The oral cavity and the pharynx]. PMID- 6911209 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The breast]. PMID- 6911210 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The respiratory system]. PMID- 6911211 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The cardiovascular system]. PMID- 6911212 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The digestive system]. PMID- 6911213 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The urogenital system]. PMID- 6911214 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The bones and joints]. PMID- 6911215 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The neuromuscular system]. PMID- 6911216 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The hematologic and hematopoietic systems]. PMID- 6911217 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). The endocrine systems]. PMID- 6911218 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). Allergy and the immune system]. PMID- 6911219 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). Psychiatric and psychological observations]. PMID- 6911220 TI - [Technics and guidelines in nursing observation (specific areas of assessment: items of observation and their significance). Pediatrics]. PMID- 6911221 TI - [Focal points of modern medicine. 7. The Japanese and alcohol. A discussion]. PMID- 6911222 TI - [Current status and future of the surgical treatment of apoplexy: the need for early treatment]. PMID- 6911223 TI - [Apoplexy at the time of hospital admission: the initial treatment and determination of its severity]. PMID- 6911224 TI - [Radiological diagnosis of apoplexy and the nurse's role in the examination]. PMID- 6911225 TI - [Early surgery in cerebral aneurysm and the pre- and postoperative care]. PMID- 6911226 TI - [New surgical methods of treating cerebral arteriovenous malformations]. PMID- 6911227 TI - [Surgical treatment of ischemic cerebrovascular disorders and the pre- and postoperative care]. PMID- 6911228 TI - [Danger signs in apoplexy patients following surgical treatment]. PMID- 6911229 TI - [Current status and future problems of patients with cerebral aneurysms]. PMID- 6911230 TI - [Respiratory care of apoplexy patients in the acute state: blood gases and the nursing objectives]. PMID- 6911231 TI - [Ventricular drainage: its importance and the factors to be observed to prevent complications]. PMID- 6911232 TI - [Pre- and postoperative nursing of patients with cerebral vasospasm]. PMID- 6911233 TI - [Keypoints in the nursing of apoplexy patients with complications]. PMID- 6911234 TI - [Nursing of a patient in a vegetative state due to a cerebral aneurysm rupture]. PMID- 6911235 TI - [Conference. The postoperative nursing of a patient with recurrent rupture of an anterior communicating artery aneurysm: assistance with independent urination]. PMID- 6911236 TI - [Science of symptomatology: skin manifestations. Itching and the mechanism of its development]. PMID- 6911237 TI - [Science of symptomatology: skin manifestations. Skin diseases associated with metabolic disorders: the observation of systemic conditions through the dermal symptoms]. PMID- 6911238 TI - [Science of symptomatology: skin manifestations. Skin protection of inpatients and the nursing approach]. PMID- 6911240 TI - [Understanding patients' needs. 8. Obstacles in recognizing the need: experiences in home care]. PMID- 6911239 TI - [Bathing of apoplexy patients: the design of a simplified tub]. PMID- 6911241 TI - [Bedside guidance in cardiology. 13. Pulmonary heart disease and pulmonary embolism]. PMID- 6911242 TI - [Disseminated intravascular coagulation in the field of pediatrics and its management]. PMID- 6911243 TI - [Disseminated intravascular coagulation in pregnancy and its treatment]. PMID- 6911245 TI - [Nursing of patients with disseminated intravascular coagulation being cared for at the intensive care unit]. PMID- 6911244 TI - [Disseminated intravascular coagulation associated with acute leukemia and nursing care]. PMID- 6911246 TI - [Disseminated intravascular coagulation complicating malignant tumor and nursing care--clinical course and medical therapy leading to discharge from the hospital and continued care at home]. PMID- 6911247 TI - [Experience in nursing of infants with disseminated intravascular coagulation]. PMID- 6911248 TI - [Therapy and nursing of disseminated intravascular coagulation caused by acute infection]. PMID- 6911249 TI - [Treatment of disseminated intravascular coagulation developing in severe burns and the practice of nursing]. PMID- 6911251 TI - [Science of symptomology: coughs. Development and physiopathology of cough]. PMID- 6911250 TI - [Conference: treatment and nursing of patients with disseminated intravascular coagulation--a study of 3 clinical cases]. PMID- 6911252 TI - [Science of symptomatology: cough. The mechanism of the respiratory control and its deviation]. PMID- 6911253 TI - [Science of symptomology: cough. The focal point in guidance of children with bronchial asthma in regard to their daily activities]. PMID- 6911254 TI - [Science of symptomology: cough. EIA (exercise induced asthma) of asthmatic children in cold weather and the optimum range of their activities]. PMID- 6911255 TI - [Understanding the patient's need: monologue by schizophrenic patients and their nursing assessment]. PMID- 6911256 TI - [Bedside guidance in cardiology. Arrhythmia]. PMID- 6911257 TI - [The basic characteristics of the blood and disseminated intravascular coagulation--the mechanism of the development of DIC]. PMID- 6911258 TI - [Physiopathology and clinical symptoms of disseminated intravascular coagulation]. PMID- 6911259 TI - [Treatment of disseminated intravascular coagulation--on the therapeutic use of anticoagulants]. PMID- 6911260 TI - [Disseminated intravascular coagulation occurring at the ICU and its management]. PMID- 6911261 TI - [A thought on a 2-year nursing college]. PMID- 6911262 TI - [Survey on the activities of graduates of the member schools of the Japanese Association of Privately-funded Nursing Colleges]. PMID- 6911264 TI - [Study of nursing and related matters (1)]. PMID- 6911263 TI - [Re-employment of inactive nurses and their training. A discussion]. PMID- 6911265 TI - [Regional characteristics of nursing schools and mobility of the graduates. 2. Graduation and employment of students of the School of Nursing, Nara Prefectural School of Medicine]. PMID- 6911266 TI - [Minerva's light: an assumed thought on nursing and man. (6). The meaning of life (2)]. PMID- 6911267 TI - [In search of a new educational encounter. 5. Thoughts given to students' lives]. PMID- 6911268 TI - [Impressions at the seminar for nursing instructors: search in one's own thought process]. PMID- 6911270 TI - [Evaluation of the curriculum in nursing education: with special reference to Buffalo University School of Nursing]. PMID- 6911269 TI - [Methods and technology of modern nursing education--with special reference to the experience in the United States]. PMID- 6911272 TI - [Welfare system suited to the economic and social conditions of the nation (1). The undercurrent concerning the welfare system]. PMID- 6911271 TI - [Regional characteristics of nursing schools and mobility of the graduates. 3. Comprehensive study of admission, graduation, and employment of the graduates of the School of Nursing affiliated with Nara Prefectural School of Medicine and suggested plan for revision of nursing education as part of regional health care]. PMID- 6911273 TI - [Medicine to meet the patient's basic desire to live]. PMID- 6911274 TI - [Minerva's light: an assumed thought on nursing and man. (7). On human sexuality]. PMID- 6911275 TI - [A question to myself: the true nature of nursing]. PMID- 6911276 TI - [Tokyo Neuroscience Laboratory Seminar: methodology in nursing education concerning primary health care: teaching planning with special emphasis on chronic diseases]. PMID- 6911277 TI - [Role of the instructor in clinical training]. PMID- 6911278 TI - [Instructional theory concerning conferences in clinical training of adult nursing in the field of internal medicine]. PMID- 6911279 TI - [Welfare system suited to the economic and social conditions of the nation. (2). Personal touch in daily lives]. PMID- 6911280 TI - [Minerva's light: an assumed thought on nursing and man. (8) Unfulfilled dream of boyhood: death of a stranger]. PMID- 6911281 TI - [Sanctity of life]. PMID- 6911282 TI - [Cooperation and unification in public health activities]. PMID- 6911283 TI - [Significance of the concept of the "action area" in the analysis of public health activities - a proposal of a focal point in the research of public health services]. PMID- 6911284 TI - [Progress of the group studying clinical cases]. PMID- 6911285 TI - [Vast land and unassuming people - an impression on China]. PMID- 6911286 TI - [Simplification of the organization of the Japan Nursing Association: a move contrary to the interest of public health nurses. Questions on exclusion of PT, OT, rehabilitation therapist, and dental hygienists and inclusion of public health nurses and midwives in the category of nurses. A discussion]. PMID- 6911288 TI - [Re-evaluation of conventional activities: revitalization of the activities applying the concept based on PHC (primary health care). The ideal and methods of re-evaluation of public health activities: analysis of activities based on the concept of PHC]. PMID- 6911289 TI - [Re-evaluation of conventional activities. Re-evaluation of the in-house training program to meet patients' needs: analysis based on PHC: health education of hospitalized patients with Basedow's disease]. PMID- 6911287 TI - [Methodology in evaluation of public health activities by the analysis based on primary health care (PHC)]. PMID- 6911290 TI - [Analysis based on PHC in re-evaluation of public health activities directed at the aged at Asahi-Ku, Yokohama-shi: nursing activities (home care) of bedridden patients]. PMID- 6911291 TI - [Re-evaluation of regional public health nursing activities based on PHC--public health activities at Manazuru-machi, Kanagawa Pref]. PMID- 6911292 TI - [Public health activities based on the concept of PHC--activities initiated at Manazura-machi. Conference]. PMID- 6911293 TI - [Re-evaluation of public health activities and the analysis based on PHC]. PMID- 6911295 TI - [Public health problems: ineptness of the public health nurse or unfairness of the bureaucrat?]. PMID- 6911296 TI - [A trial at more effective training at public health clinics: a report on clinical training of nursing students at Chigasaki Public Health Clinic]. PMID- 6911298 TI - [Movements involving public health nurses and their future problems]. PMID- 6911299 TI - [Public health actions concerning alcoholism]. PMID- 6911294 TI - [Invitation to Scotland]. PMID- 6911297 TI - [Japanese economy and the living standard of the public]. PMID- 6911300 TI - [Environmental pollution and activities of public health nurses]. PMID- 6911301 TI - [On Oriental medicine]. PMID- 6911302 TI - [Health examination of infants and young children]. PMID- 6911303 TI - [Problems of the aged and public health nursing activities]. PMID- 6911304 TI - [Reports on various sections and lecture periods]. PMID- 6911307 TI - [My public health nursing activities: lessons from the inhabitants and actions based on Christianity]. PMID- 6911306 TI - [Health of the working population in a region]. PMID- 6911305 TI - [Symposium: health problems at Matsukawa-cho; campaign for the interest of the inhabitants and public health nursing activities]. PMID- 6911308 TI - The postpartum follow-up nurse clinician. PMID- 6911310 TI - Paternal--infant bonding in the first-time father. PMID- 6911309 TI - Smoking and alcohol consumption: advice given by health care professionals. PMID- 6911311 TI - Childbirth education classes: effects on attitudes toward childbirth in high-risk indigent women. PMID- 6911313 TI - Improving nipple graspability for success at breastfeeding. PMID- 6911312 TI - The cervical cap: an alternative contraceptive. AB - The cervical cap is a convenient, inexpensive, nonhormonal and non-invasive contraceptive method. This method has potential for better effectiveness if custom-fit caps are manufactured. As more health care providers become knowledgeable in the use of the cap, more women will become aware of this contraceptive method as an alternative to oral contraceptives and intrauterine devices. Research is needed to document the most accurate method of cervical cap fitting and the effectiveness rate of the cervical cap. Nurse practitioners who counsel patients and fit them for caps are in the perfect position to start doing this research. PMID- 6911314 TI - Family support in infant death. PMID- 6911315 TI - A systems approach to adolescent pregnancy. PMID- 6911316 TI - A tool to facilitate mother--infant attachment. AB - Although the MIST is helpful, it is still in its embryonic stage of development. It will need to be refined further by practitioners and researchers to see if it is relevant to them and to different cultures and socioeconomic groups. Research must be done to see if each researcher finds the same results and if the items are significant, or if the different gradations are just arbitrary. These are important questions to be asked. We must begin to look at tools for evaluating mother--infant interactions because, until we have a tool, significant mother- infant intervention cannot begin. PMID- 6911317 TI - Chlamydial infections in women. AB - The impractical isolation procedures available to the general provider of women's health services make diagnosis difficult and often one of exclusion. Looking at the presence of antichlamydial antibodies in cervical secretions may be a more practical detector of infection. More research needs to be carried on in the area of isolation techniques. More importantly, nurse clinicians/practitioners need to be aware of the necessity of treating NGU contacts. As with many conditions, the asymptomatic carrier is the most important link in the control of the disease. Awareness of the potential of these infections will help in their control. PMID- 6911318 TI - My baby was premature. PMID- 6911319 TI - Fetal monitoring. PMID- 6911320 TI - Basics of breastfeeding. PMID- 6911321 TI - Parturition care planning. PMID- 6911322 TI - Relinquishing mothers' legal rights. PMID- 6911323 TI - [Problems in breast feeding: does the baby get enough?]. PMID- 6911324 TI - [Treatment of mastitis]. PMID- 6911325 TI - [Hypertension in the aged]. PMID- 6911326 TI - [Symposium on sterility]. PMID- 6911327 TI - [Home visiting program conducted by a local nursing association]. PMID- 6911328 TI - [11th Congress of the Japanese Nursing Association: the 1980 Committee Report]. PMID- 6911329 TI - [1980 Committee Report: at the conclusion of the 11th Congress of the Japanese Nursing Association]. PMID- 6911331 TI - [Statistical file: a transition in the number of active public health nurses]. PMID- 6911332 TI - [Volunteer home nursing activities]. PMID- 6911330 TI - [Items adopted by the ILO concerning nursing personnel and their relationship to the primary health care promoted by WHO/UNICEF]. PMID- 6911333 TI - [Private practice by a public health nurse as a health consultant]. PMID- 6911334 TI - [Potentials of inactive nurses]. PMID- 6911335 TI - [Make life as meaningful as possible: the utilization of professional nursing experience for the care of local residents]. PMID- 6911336 TI - [Public expectation of nursing]. PMID- 6911337 TI - [New era in nursing study. A discussion]. PMID- 6911340 TI - [Fibrinopeptide]. PMID- 6911338 TI - [Iatrogenic incidents involving nursing. 4. The involvement of midwives]. PMID- 6911342 TI - [If the 1985 resolution is to be rejected, what should we propose instead?]. PMID- 6911341 TI - [Medical topics. IgA nephrosis]. PMID- 6911339 TI - [Profile of a nurse. Ms. Kieko Nakajima who organized a telephone counseling service for families with senile patients]. PMID- 6911343 TI - [Interrelation of the blood kallikrein-kinin and anticoagulation systems in experimental myocardial infarct]. AB - The activity of the kallikrein-kinin and anticoagulation blood systems was studied in dogs with experimental myocardial infarction. Changes were revealed in the kallikrein-kinin system which create conditions for uncontrolled production of kinins in the first 24 hours of the disease. A direct correlation was detected between the activity of kallikrein and plasmin in the first three days of experimental myocardial infarction, which the authors claim to be a pathophysiological reaction of the body because it is conductive to the uncontrolled production of kinins. It is also noted that in this pathological process the depression of the anticoagulation system in the first two days is mainly due to reduced activity of nonenzymatic fibrinolysis, while, beginning with the third day, it is caused by reduced activity of enzymatic fibrinolysis, increased antiplasmin activity in particular. PMID- 6911344 TI - Standards of mental-health nursing practice. PMID- 6911345 TI - [Nursing, independent home]. PMID- 6911347 TI - [Clinical aspects and therapy of stomach carcinoma]. PMID- 6911346 TI - [With one another - for one another]. PMID- 6911348 TI - [Pathogenesis and clinical aspects of cor pulmonale]. PMID- 6911349 TI - [Nursing inquiry - a call of distress from Rheinland-Pfalz. The status of nursing and pediatric nursing in the hospitals of the Rhine-Pfalz district]. PMID- 6911350 TI - [When he saw him, he passed him by]. PMID- 6911351 TI - [Nursing autonomy - where has it gone?]. PMID- 6911352 TI - [They all helped]. PMID- 6911354 TI - [Patient self-help - a challenge]. PMID- 6911353 TI - [Extrauterine pregnancy]. PMID- 6911355 TI - [Control of self-help groups]. PMID- 6911356 TI - [Always with one leg in prison? Liability, civil and criminal legal consequences in the assumption of so-called medical acts]. PMID- 6911357 TI - [Early diagnosis of cancer using skin temperature measurements]. PMID- 6911358 TI - Needed: comprehensive profiles of school health educators. PMID- 6911359 TI - Dental needs in children of Mexican-American migrant workers. PMID- 6911360 TI - A proposal for certification of school nurses the West Virginia model. PMID- 6911361 TI - Assessing nutrition education practices in the high school health curriculum. PMID- 6911362 TI - Smoking-related attitudes and behaviors of parents of fourth grade students. AB - In an attempt to determine the effect of tobacco education homework on the smoking behavior and/or attitudes of parents of fourth graders, a sample of students was given homework assignments at the beginning of the school year with which their parents had agreed to help. A control sample had the regular tobacco education unit, with no homework assignments. A follow-up survey at the end of the school year revealed that for parents who had been cigarette smokers at the beginning of the school year, those in the homework sample (n = 215) reported smoking fewer cigarettes and a greater reduction in smoking than those in the nonhomework sample (n = 89). While parents in the two samples did not differ in their general attitude toward cigarette smoking, those in the homework sample were more opposed to their children starting to smoke at a later time and more approving of tobacco education introduced as early as the fourth grade. PMID- 6911363 TI - Role playing in VD education. PMID- 6911365 TI - Burns and their psychological effects on children. AB - Thousands of children are burned each year, and hundreds die from their burns. The physical wounds of burns take less time to heal than psychological wounds caused by the burns. The child will need to make adjustments in self-concept and body image as well as social adjustments. Through support of school programs in safety education and education of the community, health educators and school nurses can help prevent the high incidence and seriousness of burns. PMID- 6911364 TI - Just a pinch between the cheek & gum. AB - At least in part, through a skillful manipulation of the public by the tobacco industry, the use of smokeless tobacco is rapidly increasing, especially among young male athletes and students in high school and colleges. Advertising implies that smokeless tobacco habits are innocuous and safe, but existing scientific evidence indicates that dipping and chewing are potentially harmful to one's health. Health professionals are urged to advise patients and students concerning the potential hazards of using smokeless tobacco. Further, health professionals should take a strong public stance in opposition to the current dipping and chewing advertising campaigns aimed at youth. These advertisements totally ignore the possible health hazards of smokeless tobacco. If the tobacco companies are allowed to continue to advertise smokeless tobacco in the same manner that they use to promote cigarette smoking, then some effort should be directed to require health warnings in these advertisements. In fact, some serious consideration should most likely be given to banning this new wave of tobacco marketing in the interest of public health, just as was the case with cigarette advertisements, especially in light of the fact that these ads are primarily targeted to young boys and men. PMID- 6911366 TI - Teacher-observer of student health problems. PMID- 6911367 TI - School health educators as school health educators. PMID- 6911368 TI - "Take thou". PMID- 6911370 TI - [Policies concerning possible disasters at a hospital--with special reference to planning for seismic emergencies]. PMID- 6911369 TI - Computers maximize nurses' time. PMID- 6911371 TI - [Disasters at hospitals and the law]. PMID- 6911372 TI - [Disaster prevention and preparedness in nursing]. PMID- 6911373 TI - [Hospital disasters and personnel training]. PMID- 6911374 TI - [Patient rescue at disasters]. PMID- 6911375 TI - [Instruction for the patient with chronic disease about to be discharged and subsequent problems concerning home care]. PMID- 6911376 TI - [Nursing administration in changing conditions]. PMID- 6911377 TI - [Human science. Religion (3). Rituals and the community--in search of the origin of the rituals and communities]. PMID- 6911378 TI - [Bedside conference; planning of clinical training (6). The digestive system (2)]. PMID- 6911380 TI - [Nursing education and technological education (2)]. PMID- 6911379 TI - [Nurse in an organization: motivation and morale (3). Motivation and morale: from the nurse's viewpoint]. PMID- 6911381 TI - [A model of nursing]. PMID- 6911382 TI - [Students' interpretation of the importance of nursing activities]. PMID- 6911383 TI - [Nursing process: nursing of patients with stomach cancer. Description of stomach cancer]. PMID- 6911384 TI - [Nursing process: nursing of patients with stomach cancer. Diagnosis and treatment of stomach cancer]. PMID- 6911385 TI - [Nursing process: nursing of patients with stomach cancer. The nursing process for patients with stomach cancer]. PMID- 6911387 TI - [Nursing seminar: examination of the pulse]. PMID- 6911388 TI - [Nursing seminar: examination of the pulse. The role of the nurse in management of arrhythmia]. PMID- 6911386 TI - [Nursing process: nursing process of patients with stomach cancer. Evaluation of the nursing process. Discussion]. PMID- 6911389 TI - [Nursing seminar: examination of the pulse. Keypoints in nursing of patients with arrhythmia--study of 3 cases]. PMID- 6911390 TI - [Nursing process: the possibilities and limitations of the practice of the nursing process. Evaluation of the procedures involved in the nursing process; assessment (1)]. PMID- 6911391 TI - [Nursing and therapy: the pacemaker. Theories involved in the application of the pacemaker]. PMID- 6911392 TI - [Nursing and therapy: the pacemaker. Nursing of the patient using a pacemaker]. PMID- 6911393 TI - [In search of a new nursing philosophy. VIII. Nurturing of nursing philosophy in nursing students]. PMID- 6911394 TI - [Assistance of a patient with spinal cord injury in acquiring a desire for recovery]. PMID- 6911395 TI - [Test yourself: nursing of a child with bronchial asthma]. PMID- 6911396 TI - [Clinical essay. Knowledge and wisdom]. PMID- 6911397 TI - [Nursing process: nursing of patients with cleft lip and cleft palate. Diagnosis of cleft lip, cleft alveolus, and cleft palate]. PMID- 6911398 TI - [Nursing process: nursing of patients with cleft lip and cleft palate. Treatment of cleft lip and cleft palate]. PMID- 6911399 TI - [Nursing process: nursing of patients with cleft lip and cleft palate. Nursing process for patients with cleft lip and cleft palate]. PMID- 6911400 TI - [Nursing process: nursing of patients with cleft lip and cleft palate. Nursing of a patient with cleft lip and cleft palate in a clinical example]. PMID- 6911401 TI - [Nursing process: nursing of patients with cleft lip and cleft palate. Evaluation of the nursing process. Discussion]. PMID- 6911402 TI - [Nursing seminar--evaluation of respiration. Observation and examination of the respiratory function]. PMID- 6911403 TI - [Nursing seminar--evaluation of the respiratory function. Evaluation of the respiratory function and the care of patients with respiratory insufficiency]. PMID- 6911405 TI - [Nursing process: possibilities and limitations of its application. Evaluation of the procedures of each step: assessment. (2)--collection of the information useful in recognizing the problem]. PMID- 6911404 TI - [Nursing seminar--evaluation of the respiratory function. Respiratory care practiced at the ICU]. PMID- 6911406 TI - [Nursing and therapy: traction therapy. Traction: its application and methodology]. PMID- 6911407 TI - [Nursing and therapy: traction therapy. Nursing of a patient with traction]. PMID- 6911408 TI - [In search of humane nursing. The nurse and assistance for a patient who lost the phonation function--care and speech rehabilitation of the voiceless patient after a pharyngectomy due to pharyngeal cancer]. PMID- 6911409 TI - [Seeking new nursing philosophy. IX. At the death of an infant]. PMID- 6911410 TI - [Test yourself. Nursing of a patient with chronic kidney failure]. PMID- 6911411 TI - [Clinical essay. Medical care of Cambodian refugees]. PMID- 6911412 TI - [Clinical forms of goiter]. PMID- 6911413 TI - [Hashimoto's goiter and its treatment]. PMID- 6911414 TI - [Hypothyroidism]. PMID- 6911415 TI - [Hypothyroidism in young infants]. PMID- 6911416 TI - [Subacute thyroiditis]. PMID- 6911417 TI - [Emergency states in thyroid pathology]. PMID- 6911418 TI - [Emergency states in endocrinology]. PMID- 6911419 TI - [Diabetes insipidus]. PMID- 6911420 TI - [Pheochromocytoma]. PMID- 6911421 TI - [Itsenko-Cushing's syndrome]. PMID- 6911422 TI - [Juvenile gynecomastia]. PMID- 6911423 TI - [Methods of preventing infections in the heart surgery clinic]. PMID- 6911424 TI - [Genetic reasons for drug side effects]. PMID- 6911425 TI - [Use of drugs in aerosol containers]. PMID- 6911426 TI - [Ethical bases of the interrelationships of paramedical workers with patients]. PMID- 6911427 TI - Partial resistance to methemoglubin-induced acute renal failure in rats recovering from prior renal failure. PMID- 6911428 TI - [Renal hormones. The kallikrein, kinin and prostaglandin systems]. PMID- 6911429 TI - President's message. PMID- 6911430 TI - The EEC recommendations and modular training in the operating department for learner nurses. PMID- 6911431 TI - Ways in which effective cost saving could be made in the operating department. PMID- 6911432 TI - Anaesthetics in Holland--a personal view. PMID- 6911433 TI - The work of the NATN public relations committee. PMID- 6911434 TI - The organisation and management of operating departments. PMID- 6911435 TI - Implementing counts in the operating room. PMID- 6911436 TI - One hospital's successful implementation of primary nursing. PMID- 6911437 TI - NAQ legal forum: the ethical implications of informed consent. PMID- 6911438 TI - After primary nursing is implemented: then what? PMID- 6911439 TI - On the scene: Beth Israel Hospital. PMID- 6911440 TI - Nursing education: a resource for primary nursing development. PMID- 6911442 TI - The clinical advisor as a primary nurse support. PMID- 6911441 TI - Patient advocacy in primary nursing. PMID- 6911443 TI - Peer support in implementing primary nursing. PMID- 6911444 TI - Primary nurse/primary therapist. PMID- 6911445 TI - A cardiac rehabilitation program in a primary nursing setting. PMID- 6911446 TI - Primary nursing in the oncology ambulatory setting. PMID- 6911447 TI - Primary nursing in a clinical research center. PMID- 6911449 TI - Primary nursing and the care and management of the elderly. PMID- 6911448 TI - Primary nursing: a greater opportunity for patient independence. PMID- 6911450 TI - Orientation for the primary nurse role. PMID- 6911451 TI - Primary nursing: practice and staff issues. PMID- 6911452 TI - Primary nursing's effect on professional development. PMID- 6911454 TI - NAQ forum: primary nursing. PMID- 6911453 TI - Research--a friend of primary nursing. PMID- 6911455 TI - Primary nursing in neurological nursing. PMID- 6911456 TI - The still unanswered questions about primary nursing. PMID- 6911457 TI - Will primary nursing survive in the 80s? PMID- 6911458 TI - Primary nursing phase 1: 1980--the year of explosive beginnings. PMID- 6911459 TI - Primary nursing phase 2: a public relations campaign. PMID- 6911460 TI - A model for evaluating primary nursing. PMID- 6911461 TI - Test your knowledge of common medical problems. PMID- 6911462 TI - Broken promises. PMID- 6911463 TI - Medication errors: use accepted abbreviations in medication orders. PMID- 6911464 TI - Liability for death: nine nurses' legal ordeals. PMID- 6911465 TI - Pain. Angina pectoris: how to recognize it; how to manage it. PMID- 6911466 TI - Turning an impossible situation into a manageable one. Nursing grand rounds. PMID- 6911467 TI - Teaching is a two way street. PMID- 6911468 TI - Danger: you are... facing the violent patient. PMID- 6911469 TI - A care plan that really works for children on long-term I.V. therapy. PMID- 6911471 TI - Skillcheck: on assessing abnormal organ function. PMID- 6911470 TI - Timely techniques in caring for the patient with an endotracheal tube. Part 1. PMID- 6911472 TI - Drug alert: two forms of dilantin. PMID- 6911473 TI - Concussion. PMID- 6911474 TI - Self-esteem: an answer to the nurse's dilemma. PMID- 6911476 TI - Reality breakdown. PMID- 6911475 TI - Wanted: uniform quality assurance standards for registries. PMID- 6911477 TI - Safety, noise and communication. PMID- 6911478 TI - Hydrotherapy 2: caring for pool staff. PMID- 6911479 TI - Stress: cause and effects outside the workplace. PMID- 6911480 TI - Safety: organic solvents--their uses and hazards. PMID- 6911481 TI - VDUs--the outcome of a screen test. PMID- 6911483 TI - Stress: its effects on people at work. PMID- 6911482 TI - Court damages: how a preexisting medical condition can affect a settlement. PMID- 6911484 TI - Safety: the scrutiny and control of new toxic substances. PMID- 6911485 TI - Glaucoma and occupational health nursing. PMID- 6911486 TI - Heat injury syndromes. PMID- 6911487 TI - Occupational health nurses, a periodic screening examination program, and the computer. PMID- 6911488 TI - Physical fitness programs in industry: applications of social learning theory. PMID- 6911489 TI - Advances in cataract surgery. PMID- 6911490 TI - Visual acuity. PMID- 6911491 TI - Medical surveillance--a way to go. PMID- 6911492 TI - Power: how to get it and keep it. PMID- 6911493 TI - The employed pregnant worker: the risks of physical exertion. PMID- 6911494 TI - Obesity--incidence, causes, prevention and treatment. PMID- 6911495 TI - Recognition of drug and alcohol use and abuse. PMID- 6911496 TI - Priorities in trauma management. PMID- 6911497 TI - Doing better, yet feeling worse. PMID- 6911498 TI - Primary nursing. PMID- 6911499 TI - Detachment: the road towards recovery. PMID- 6911500 TI - [Alcoholism and drug addiction.1]. PMID- 6911501 TI - [The Glasgow Coma Scale]. PMID- 6911502 TI - [A modern basic care hospital in Baden]. PMID- 6911503 TI - [Utopists, technocrats, romantics (or whatever?) in community psychiatry]. PMID- 6911504 TI - [The newborn infant and its parents in the hospital]. PMID- 6911505 TI - [Hygiene via byways. Interview by Hannelore Burstmayr]. PMID- 6911506 TI - [Alcoholism and drug addiction. 2]. PMID- 6911507 TI - [The relationship of graduate nursing personnel to their profession]. PMID- 6911508 TI - [WHO's intermediate program for nursing and midwifery in Europe. Introduction of the nursing process in Austria]. PMID- 6911509 TI - [The nursing profession in the pressure area between responsibility and subordination]. PMID- 6911510 TI - [Historical causes of the pressure field]. PMID- 6911512 TI - [Principles and goal proposals of the Austrian Nurses' Association]. PMID- 6911511 TI - [Nursing tomorrow - closer to the patient]. PMID- 6911513 TI - [Anxiety or information in the hospital. 1]. PMID- 6911514 TI - Inflation: prospects and predictions for the Pennsylvania Nurses Association. PMID- 6911515 TI - How PNA dues stack up compared to other organizations. PMID- 6911516 TI - Management of conflict. PMID- 6911517 TI - Conflict and strategies for conflict management. PMID- 6911518 TI - Conflict and diploma nursing education. PMID- 6911519 TI - Conflict and diploma nursing education. PMID- 6911520 TI - Conflicts arising in the process of curriculum revision. PMID- 6911521 TI - Conflicts in the curriculum revision process. PMID- 6911522 TI - The administrator of the diploma program in nursing manages conflict. PMID- 6911523 TI - Criteria for the evaluation of educational programs in practical nursing. PMID- 6911524 TI - Systems of life No 76, Systems and signs: digestive system - 2. Abdomen. Inspection. PMID- 6911525 TI - Ward sisters and their influence upon nurse learners. PMID- 6911526 TI - Geriatric patients and nurse learners' attitudes - 2. PMID- 6911527 TI - The facts of life--and death. PMID- 6911528 TI - The only solution. PMID- 6911529 TI - The other side of paediatrics. PMID- 6911530 TI - Traditional medicine. PMID- 6911531 TI - Nursing care study: that was her life. PMID- 6911533 TI - A screen for intensive care units. PMID- 6911532 TI - Communication in nursing--1. The Nursing Research Unit, University of Edinburgh. PMID- 6911534 TI - How should nursing be managed below the level of director of nursing services? PMID- 6911535 TI - A psychiatric sister's ABC - 5. PMID- 6911536 TI - Communication skills: talking points. 10. What if I said no? PMID- 6911537 TI - Injections--a humble task? PMID- 6911538 TI - Trends in psychiatric nursing research. PMID- 6911540 TI - The jobless mind. PMID- 6911539 TI - The nurse and the patient Communication skills: questions and listening. PMID- 6911541 TI - Plugging all the gaps. PMID- 6911542 TI - Child abuse inquiries. PMID- 6911543 TI - She loves me--she loves me not. PMID- 6911544 TI - Reflections on the role of a stoma care nurse. PMID- 6911545 TI - Stoma care after cystectomy and ileal conduit formation: the role of the stoma care nurse. PMID- 6911546 TI - Preliminary experience with Natuderm, used as a protective on peristomal skin. PMID- 6911547 TI - Statistics for nurse managers--2. Avoiding common pitfalls and hazards. PMID- 6911548 TI - The nursing process in action - 2. The nursing process. 1. Teaching and evaluating care. PMID- 6911549 TI - The nursing process in action - 2. The nursing process. 2. The teaching program. PMID- 6911550 TI - The nursing process in action - 2. The nursing process. 3. A student's viewpoint. PMID- 6911551 TI - Communication skills: talking points. 21. She's not gone, she's in the loo. PMID- 6911553 TI - Pastry surprise. PMID- 6911552 TI - Organising a library for the school of nursing. 2. Classification and cataloguing. PMID- 6911554 TI - Systems of life No 79. Systems and signs: digestive system - 5. The acute abdomen. PMID- 6911555 TI - Do the mentally handicapped need specialist community nursing care? PMID- 6911556 TI - Ultraviolet rays and its effects on human skin. PMID- 6911557 TI - Nursing care study: total laryngectomy for advanced carcinoma of the larynx. PMID- 6911558 TI - How nurses and neurotic patients view each other in general hospital psychiatric units. PMID- 6911559 TI - Statistics for nurse managers--3. Some basic techniques. PMID- 6911561 TI - Alcohol-associated drowning. PMID- 6911562 TI - Letter from America. PMID- 6911560 TI - The nursing process in action--3. The nursing process related to mental handicap care. PMID- 6911563 TI - Communication skills: talking points. 22. Shall we go now? PMID- 6911565 TI - A new voice for psychiatric nursing. PMID- 6911564 TI - The under fives in hospital: a report on the emotional well-being of children aged 0-5 years in hospital. PMID- 6911566 TI - Unity in the community? PMID- 6911567 TI - The impossible dream. PMID- 6911568 TI - Monitoring dental problems in the school: a practical experiment (1973-79). PMID- 6911569 TI - Nursing care study: a young patient with cystic fibrosis. PMID- 6911570 TI - The nursing process in action-6. The nursing process in community nursing. PMID- 6911571 TI - The patient care study as a learning and assessment tool in nurse education. PMID- 6911572 TI - A family support unit. PMID- 6911573 TI - Letter from America. PMID- 6911574 TI - Systems of life No 80. Systems and signs: reproductive system - 1. Mostly male. PMID- 6911575 TI - Shared treatment facilities--an evaluation. PMID- 6911576 TI - No room for sacred cows. Interview by Laurence Dopson. PMID- 6911577 TI - Moving out. PMID- 6911578 TI - The price of professionalism? PMID- 6911579 TI - An unexpected visitor. PMID- 6911580 TI - Trouser suit. PMID- 6911581 TI - Combined degree course in mental handicap nursing. PMID- 6911582 TI - Combined degree course in mental handicap nursing. Training is provided in two vital areas of care. PMID- 6911583 TI - Combined degree course in mental handicap nursing. There will always be someone who cannot be cared for at home. PMID- 6911584 TI - Combined degree course in mental handicap nursing. 'I am hopeful that future work within the hospital will move towards education and training'. PMID- 6911586 TI - Tales of Saudi Arabia. PMID- 6911585 TI - Nursing care study: multiple pathology in old age--a nursing approach to the problems. PMID- 6911587 TI - Talking points. 24. I'm not going down there no more. PMID- 6911588 TI - Breast augmentation using the silicone prosthesis. PMID- 6911589 TI - Recorded patient-nurse interaction--an advance in psychiatric nursing. PMID- 6911590 TI - Coronary care goes mobile. PMID- 6911591 TI - Hidden handicaps. Listen, I want to tell you something. PMID- 6911593 TI - Hidden handicaps. The deaf and hard of hearing: some hints. PMID- 6911592 TI - Hidden handicaps. Incontinence--a forward look. PMID- 6911594 TI - Hidden handicaps. The forbidden foods. PMID- 6911596 TI - Hidden handicaps. The sick headache. PMID- 6911595 TI - Hidden handicaps. Migraine: current research and treatment. PMID- 6911597 TI - Grassroot guidelines. PMID- 6911598 TI - Time to seize the initiative. PMID- 6911599 TI - Profile of a president: Eunice Muringo Kiereini. PMID- 6911600 TI - Allergy ignorance. PMID- 6911602 TI - Curriculum innovation in nurse training: a school-based approach. PMID- 6911601 TI - Nursing care study: severe brain damage following multiple circulatory arrests. PMID- 6911603 TI - Admission to hospital. PMID- 6911604 TI - Treating subarachnoid haemorrhage using carotid ligation. PMID- 6911605 TI - A family close to crisis: prevention proved to be better than cure for this family. PMID- 6911606 TI - A personal view of nursing research. PMID- 6911608 TI - Nursing in a boarding school. PMID- 6911607 TI - How to promote successful breast-feeding. PMID- 6911609 TI - Symposium on respiratory care. PMID- 6911610 TI - Assessment of the individual with altered respiratory function. PMID- 6911611 TI - Bedside monitoring of respiratory function. AB - The primary focus of any monitoring technique is to alert the practitioner to change. Assessment, evaluation, and analysis of the data provide the basis for clinical decision-making. Monitoring spontaneous ventilatory parameters offers an overall assessment of the effectiveness of maintaining pulmonary gas exchange. Blood gas analysis provides the cornerstone for evaluating cardiopulmonary status and is an essential tool. The evaluation of dead space and shunt provides a foundation for differentiation between ventilation and perfusion mismatching. Collectively, these assessments focus on the stability of the cardiovascular and respiratory systems. Although modern technology is continually producing increasingly sophisticated methods of respiratory function monitoring, experienced observation by the clinician is still the key to successful assessment. PMID- 6911612 TI - Vascular pressures and critical care management. AB - The circulation of blood in the body is a closed system dependent on the heart as a pump and the vessels for movement. Movement or flow of blood is dependent on pressure gradients and resistance within the vessels. Changes in one part of the system affect other parts of the system. Changes in the flow of blood can be calculated by monitoring pressures. Changes in the pressures in remote parts of the system can be calculated by measurement of pressures in accessible parts of the system (for instance, the radial artery). Pressure monitoring at the bedside can provide valuable objective data to help determine appropriate nursing care. An understanding of the relationship between parts of the circulatory system and of the intravascular pressures strengthens the ability of nurses to give expert patient care. PMID- 6911613 TI - Application and assessment of oxygen therapy devices. PMID- 6911614 TI - A home care program for patients with chronic lung disease. PMID- 6911615 TI - Pulmonary rehabilitation. PMID- 6911616 TI - The challenge of the gram-negative rod in today's hospitals. PMID- 6911617 TI - Clinical problems in the adult with asthma. PMID- 6911618 TI - Symposium on hypertension. PMID- 6911619 TI - Opportunities for nurses in high blood pressure control. PMID- 6911620 TI - Patient education for blood pressure control. PMID- 6911621 TI - Adherence to therapy in hypertensive patients. PMID- 6911622 TI - Long-term control of hypertension. PMID- 6911623 TI - March of an idea. PMID- 6911624 TI - Community initiative for better health pays off. PMID- 6911625 TI - Role of the community health worker. PMID- 6911626 TI - People's health in people's hands. PMID- 6911627 TI - Preparation of health workers. PMID- 6911629 TI - A call for justice. PMID- 6911628 TI - World Health Day, 1981. PMID- 6911630 TI - More a matter of survival! PMID- 6911631 TI - Off the record: from one RMN to three others. PMID- 6911632 TI - Reorganization--here we go again! PMID- 6911634 TI - Reorganisation--a change for the better? PMID- 6911633 TI - Reorganisation--a change for the better? PMID- 6911635 TI - Reorganisation--a change for the better? PMID- 6911636 TI - Reorganisation--a change for the better? PMID- 6911637 TI - Reorganisation--a change for the better? PMID- 6911638 TI - Reorganisation--a change for the better? PMID- 6911639 TI - Reorganisation--a change for the better? PMID- 6911641 TI - The petulance of the TUC. PMID- 6911640 TI - Reorganisation--a change for the better? PMID- 6911642 TI - Reorganisation--a change for the better? PMID- 6911643 TI - Nuclear medicine and nursing. 2. A picture of health? PMID- 6911644 TI - Student's forum -- let's look at a problem: varicose veins. PMID- 6911645 TI - A nurse's view: 'They'll never believe me'. PMID- 6911646 TI - Karamoja: fighting the famine. PMID- 6911647 TI - Patient's page: I am a better person. PMID- 6911648 TI - Research: a creative climate. PMID- 6911649 TI - Paediatrics: a cause for crying. PMID- 6911651 TI - Midwifery. 1. PMID- 6911650 TI - Filth, squalor and lice. Self neglect in the elderly. PMID- 6911652 TI - Midwifery. 1. Prevention of prematurity. PMID- 6911653 TI - Midwifery. 1. Detection of fetal abnormality. PMID- 6911654 TI - Midwifery. 1. Dynamic tests of fetal well-being. 1: Fetal movement recording. PMID- 6911655 TI - Midwifery. 1. Dynamic tests of fetal well-being. II: Antenatal cardiotocography. PMID- 6911656 TI - Midwifery. 1. Induction of labour. PMID- 6911659 TI - May your visit be a long one. PMID- 6911658 TI - Midwifery. 1. The diary of a postnatal patient. PMID- 6911657 TI - Midwifery. 1. Partography. PMID- 6911660 TI - Nursing in the army: on duty to care. PMID- 6911661 TI - Law and the nurse. 6. Damages: who carries the can? PMID- 6911662 TI - Students' forum. Let's look at a problem: Parkinson's disease. PMID- 6911663 TI - Using literature in nurse education: a novel approach. PMID- 6911664 TI - Agoraphobia. 2. Learning to enjoy the great outdoors. PMID- 6911665 TI - Nursing care study. Peptic ulcer: bleeding on the inside. PMID- 6911666 TI - What price for a peaceful settlement? PMID- 6911667 TI - Cure our 'pain in the neck' first. PMID- 6911668 TI - RAF nursing today: in sky's the limit. PMID- 6911669 TI - Law and the nurse. 7. The law and the learner. PMID- 6911670 TI - Community midwifery - and I'm being paid to do it! PMID- 6911672 TI - Midwifery education: actions speak louder than words. PMID- 6911671 TI - Midwifery education: the right course to take. PMID- 6911673 TI - Maternal counselling: first steps in motherhood. PMID- 6911674 TI - Respiratory distress syndrome: the breath of life. PMID- 6911675 TI - Drugs and breast-feeding: like mother, like son? PMID- 6911676 TI - Rubella immunity: rubella roll call. PMID- 6911677 TI - Who's holding the baby now? PMID- 6911678 TI - Get your message across! PMID- 6911679 TI - Deafness in childhood: communication breakdown. PMID- 6911681 TI - True courage: a most courageous man. PMID- 6911680 TI - Out-patient departments: patients first! PMID- 6911682 TI - My American adventure: 1980 NM cancer nursing scholarship. PMID- 6911683 TI - Nurse education: two into one will go. PMID- 6911684 TI - Chemotherapy of tuberculosis: TB or not TB? PMID- 6911685 TI - Varicose ulcers. 1. Breaking down in vein. PMID- 6911686 TI - Community psychiatric nurses: value for money? PMID- 6911687 TI - Nursing care study. Carcinoma of the colon: from one nurse to the others. PMID- 6911688 TI - Profile: dial B for Bendall. Interview by Tamara Ross. PMID- 6911689 TI - Radical health staff rule, OK? PMID- 6911690 TI - Give the people the facts! PMID- 6911691 TI - Staff stress on intensive care units: this is the age of the strain. PMID- 6911692 TI - Getting the point. PMID- 6911693 TI - The People's March for Jobs: blisters, bruises and bravery. PMID- 6911694 TI - Psychiatry: condemned by the majority? PMID- 6911695 TI - Varicose ulcers. 2. Rewarding remedies. PMID- 6911696 TI - Pain experiences. PMID- 6911697 TI - Nursing care study. Haemophilia: an accident of birth. PMID- 6911698 TI - The unkindest cut of all? PMID- 6911700 TI - Nursing division of the DHSS: top of the tree. PMID- 6911699 TI - Mock brain and body power? PMID- 6911701 TI - Male obstetric nurse: my trip into a woman's world. PMID- 6911702 TI - Helping the elderly to leave hospital: patient thinking. PMID- 6911703 TI - Problem orientated research: practice makes perfect. PMID- 6911704 TI - Resource allocation: fair shares. PMID- 6911705 TI - Plasmapheresis: simple separation. PMID- 6911706 TI - Chlorpromazine: it leaves me cold! PMID- 6911707 TI - Nursing care study. Problems of the elderly: not an isolated case. PMID- 6911708 TI - Nursing care study. Psychiatry: my relationship with Peter. PMID- 6911709 TI - Prevention is better than cure. PMID- 6911710 TI - Practice nurses and GPs. Joining professional forces. PMID- 6911711 TI - Equality in the team. PMID- 6911712 TI - Practice nurses and GPs. Present practice. PMID- 6911714 TI - Practice nurses and GPs. Changes for the better. PMID- 6911713 TI - Practice nurses and GPs. Future developments. PMID- 6911715 TI - The Portuguese connection. PMID- 6911716 TI - Geriatric care: a matter of principle. PMID- 6911717 TI - Ectopic pregnancy. PMID- 6911718 TI - Missionary midwife. James Herriot to the rescue! PMID- 6911719 TI - Nurses in research: a way to bridge the gap. PMID- 6911720 TI - Learning methods: variation on a theme. PMID- 6911721 TI - Manic depression: a token gesture. PMID- 6911722 TI - Bilateral hip arthroplasty. Two hips for old. PMID- 6911723 TI - The great debate: 'we need more money now!'. PMID- 6911724 TI - Unwrapping the package. PMID- 6911726 TI - Nuclear medicine and nursing: tracing disease to its source. PMID- 6911725 TI - The myth of the informal patient. PMID- 6911727 TI - Diary of a VAD 1940-9. Adventures in the Australian bush. PMID- 6911728 TI - Elsie Stephenson Memorial Lecture I. Past aspirations--present hopes. PMID- 6911729 TI - The hospital chaplain's role--strictly confidential. PMID- 6911730 TI - Psychiatry--some French findings. PMID- 6911731 TI - Care evaluation: sizing up the scores. PMID- 6911732 TI - Myocardial infarction: what happens when I get home? PMID- 6911733 TI - Dizziness in the elderly--giddy in old age. PMID- 6911734 TI - Multiple sclerosis: plan from the start. PMID- 6911735 TI - The road to despair. PMID- 6911736 TI - Client-centered emergency care. PMID- 6911737 TI - Now it's the nurse who needs emergency care. PMID- 6911738 TI - The law of emergency care. PMID- 6911740 TI - [Intramuscular injections in infants]. PMID- 6911739 TI - Malpractice insurance for nurses: legal, ethical and professional issues. PMID- 6911741 TI - [Patient after a fracture of the upper thigh]. PMID- 6911742 TI - [Maternal and child health care in the world]. PMID- 6911744 TI - [New disciplines]. PMID- 6911743 TI - [Correspondence studies?]. PMID- 6911745 TI - [Stages in the nursing process]. PMID- 6911746 TI - [Professional activities in the world]. PMID- 6911748 TI - [Diphtheria]. PMID- 6911747 TI - [For sick children]. PMID- 6911749 TI - [Functional disorders in lung diseases]. PMID- 6911751 TI - [Question of regulations continues open]. PMID- 6911750 TI - [Nutrition of older persons]. PMID- 6911752 TI - [Regarding education]. PMID- 6911753 TI - Ambulatory gynecology. PMID- 6911755 TI - Papanicolaou cervical smears for screening in asymptomatic women. AB - The annual Papanicolaou smear as a screening test for cervical cancer is evaluated on the basis of cost-effectiveness, predictive value, and other factors of patient selection and comparative trends in mortality rate before and after the introduction of screening programs. For the asymptomatic woman at normal risk for cancer, Papanicolaou smears are recommended only once every five years, although symptomatic or high-risk women should still maintain an annual screening schedule. PMID- 6911754 TI - Role of the primary physician in the detection and treatment of gynecologic cancer. AB - Early detection is the cornerstone of successful treatment of gynecologic cancer. The primary physician should be able to identify patients at increased risk for a malignant lesion and be familiar with simple techniques of office detection. For those patients who require referral to the subspecialist in gynecologic oncology, collaboration of the oncologist with the primary physician is essential for optimal treatment, follow-up, and rehabilitation of the cancer patient. PMID- 6911756 TI - An overview of hospital gynecologic practice. AB - Table 1 presents an overview of current gynecologic practice in hospitals as illustrated by three New England states. We believe the balance of diagnoses and operations displayed are reasonably typical of practice elsewhere in the United States. However, since operative rates are lower in New England than in other parts of the country, the proportions of women undergoing hysterectomy or a sterilization procedure will be somewhat higher elsewhere. The general issue of variation in rates of diagnoses and operations is presented; professional uncertainty is a fact which may account for the variation. Further controlled studies are urgently needed to decrease this element of uncertainty and to distinguish too much diagnosis and treatment from too little. Ultimately, nothing less will meet the standards of the best care for patients or satisfy health insurance or government programs that premiums or taxes are supporting an appropriate level of health care. PMID- 6911757 TI - Contraception. PMID- 6911758 TI - Human sexuality. Management for the primary physician. PMID- 6911759 TI - Genetic approach to gynecologic and obstetric problems. PMID- 6911760 TI - Advocacy--the challenge. PMID- 6911761 TI - The nature of atrial receptors responsible for the increase in urine flow caused by distension of the left atrium in the dog. AB - In dogs anaesthetized with alpha-chloralose the effects of distension of a large balloon in the lumen of the left atrium on the discharge of action potentials in vagal fibres and on urine flow were studied with the cervical vagi cooled at 18 and 12 degrees C. Distension of the balloon in seven dogs resulted in an increase in urine flow. Cooling the cervical vagi to 18 degrees C reduced the response to 70% of that obtained at 37 degrees C, and at 12 degrees C the response was reduced to 28%. In a second group of dogs, the effect of distension of the balloon on atrial receptors which discharged into myelinated nerve fibres of the vagi, i.e. Paintal type A and type B receptors, was examined. The increase in the activity of these receptors was reduced to 68% when the vagus nerve was cooled to 18 degrees C and was reduced further to 25% at 12 degrees C., In a third group of dogs, the effect of distension of the balloon on receptors which discharged into non-myelinated nerve fibres in the vagi was examined. Cooling of the cervical vagi also reduced the evoked increase in activity in these fibres; this reduction in activity occurred over a wider range of temperature, unlike the effect of cooling on the response in myelinated vagal fibres. It is concluded that the increase in urine flow caused by distension of a balloon in the left atrium is mediated solely by the Paintal-type atrial receptors which discharge into the myelinated fibres in the vagi. PMID- 6911762 TI - Identification of two strains of cultured canine renal epithelial cells (MDCK cells) which display entirely different physiological properties. AB - Cultured monolayers of Madin-Derby canine kidney (MDCK) cells grown upon permeable filter supports display many features of in vivo epithelia. Measurements of transmonolayer resistance, open-circuit p.d., dilution and bi ionic p.d.s have been made of MDCK monolayers mounted in Ussing-type chamber (0.75 cm window radius). Previously reported values of transmonolayer resistance of 100 omega cm2 (Cereijido, Robbins, Dolan, Rotunno & Sabatini, 1978; Misfeldt, Hamamoto & Pitelka, 1976) indicate a 'leaky' epithelium. The major finding of this work is that MDCK monolayers can also display values of transmonolayer resistance similar to 'tight' epithelia (mean value = 4116 omega cm2). The reason for such differences is the existence of separate strains of MDCK cells. High resistance monolayers originate from cell stocks of sixty serial passages whilst low-resistance monolayers originate from cell stocks of 109 serial passages. Measurements of transmonolayer dilution, and bi-ionic p.d.s together with Na ion tracer fluxes and electron microscope observations of La3+ penetration through the apical tight junctions, substantiate the finding of high-resistance properties in MDCK monolayers and confirm the existence of two separate MDCK cell strains displaying entirely different physiological properties. Differences extend to cellular morphology and cellular volume in the two strains of MDCK cells. PMID- 6911763 TI - The effects of progesterone on glucose and lactate metabolism in ovariectomized sheep. AB - In nine samples from four ovariectomized sheep the mean plasma concentration of progesterone was 0.19 +/- 0.04 ng/ml. After the subcutaneous implantation of 3 x 375 mg of progesterone in silicone rubber the concentration rose to 3.8 +/- 0.51 ng/ml at 48 h and fell steadily to 1.5 ng/ml at 21 days. Removal of the implants caused a reduction to pre-implantation values by 48 h. The increased concentration of circulating progesterone after implantation had no significant effect on the concentration of glucose in plasma, its total entry rate, irreversible loss or on plasma lactate concentration. Glucose recycling increased from 0.13 +/- 0.05 to 0.38 +/- 0.12 mg min-1 kg-1 (P less than 0.05). Lactate entry rate fell from 1.68 +/- 0.16 to 1.12 +/- 0.10 mg min-1 kg-1 (P less than 0.02). The total net formation of lactate from glucose fell from 0.56 +/- 0.05 to 0.41 +/- 0.08 mg min-1 kg-1 (P less than 0.05). The production of lactate from non-glucose substrates fell from 1.15 +/- 0.11 to 0.70 +/- 0.04 mg min-1 kg-1 (P less than 0.02). The utilization of lactate for purposes other than glucose synthesis fell from 1.50 +/- 0.14 to 0.97 +/- 0.09 mg min-1 kg-1 (P less than 0.05). The results support the view that progesterone produces an increase in glucose recycling by pathways involving compounds other than lactate. PMID- 6911764 TI - Do the blood vessels of the antler velvet of the red deer have an adrenergic innervation? AB - Samples of antler velvet and pedicle skin of Red deer were snap-frozen, freeze dried and treated with hot formaldehyde vapour. Sections (4 microns thick) were epi-illuminated with ultra-violet light. No blue-green fluorescence characteristic of adrenergic nerves was seen in sections from the antler velvet except in one castrate, although the blood vessels of the pedicle skin were well innervated. Yellow fluorescence characteristic of 5-hydroxytryptamine was present in mast cells in the velvet. The lack of a discrete adrenergic vasomotor innervation of the antler blood vessels makes it unlikely that antlers in velvet control heat loss by functioning as heat radiators. PMID- 6911765 TI - Blockbuster lawsuits: nurse defendants. PMID- 6911766 TI - Unprofessional nursing conduct: legal definition. PMID- 6911768 TI - [Nursing care at night, nursing care during the day]. PMID- 6911769 TI - [It is night that chooses you]. PMID- 6911767 TI - Legal case briefs for nurses. CT: 3.6 million dollars: RN negligence. FL: Disoriented patient: poor supervision. PMID- 6911770 TI - [Night work and sinecure]. PMID- 6911771 TI - [To start a dialogue or the sun has a rendez-vous with the moon . Interview by F. Dambreville]. PMID- 6911772 TI - [Night, death]. PMID- 6911773 TI - [An emergency]. PMID- 6911774 TI - [Sleep is half of one's health]. PMID- 6911775 TI - [Official text. schools preparing for the state diploma of nursing]. PMID- 6911776 TI - [Sleep drugs]. PMID- 6911777 TI - Are internship/residency programs for nurses feasible? PMID- 6911779 TI - On nearing the end of my term of office: address by President. PMID- 6911780 TI - Charting tomorrow today: inaugural address. PMID- 6911778 TI - A nursing adventure: through a very small window. PMID- 6911781 TI - The future: roadblocks and remedies. Farewell address. PMID- 6911782 TI - [The meeting at Strasbourg]. PMID- 6911783 TI - [Lung changes after paraquat as an experimental model of the respiratory distress in the newborn and diffuse interstitial fibrosis of the lung]. PMID- 6911784 TI - [Masked depressive states]. PMID- 6911785 TI - [Why psychiatric care?]. PMID- 6911786 TI - [Understanding hysteria]. PMID- 6911787 TI - [Hypochondria and transplantation]. PMID- 6911788 TI - [Attempted suicide]. PMID- 6911789 TI - [Violence]. PMID- 6911790 TI - [Psychiatric infrastructures in France]. PMID- 6911792 TI - [Professional education of nursing personnel in the psychiatric sector (modification of the regulations of 6 February 1973)]. PMID- 6911791 TI - [Evolution of mental health services in Europe]. PMID- 6911794 TI - [Hospitalization and emergencies in psychiatry]. PMID- 6911793 TI - [How is mental pathology regarded in the general hospital?]. PMID- 6911796 TI - [Emergencies in psychiatry. An indispensable relational responsibility]. PMID- 6911795 TI - [Drug addiction in emergency conditions and the nurse's role]. PMID- 6911797 TI - [Mental confusion]. PMID- 6911798 TI - [Agitation in emergencies]. PMID- 6911799 TI - [Emergencies in psychiatry. Introduction]. PMID- 6911800 TI - [Psychotropic agents in emergencies]. PMID- 6911801 TI - [Suicide]. PMID- 6911802 TI - [Psychiatric emergencies in incarcerated persons and prisoners. Nurses' experience in the Cusco ward in Hotel-Dieu of Paris]. PMID- 6911803 TI - [Several concrete cases of intervention in psychiatric emergency situations]. PMID- 6911804 TI - [The organization of psychiatric services in Paris]. PMID- 6911806 TI - [Latent aggressiveness]. PMID- 6911807 TI - [Aggression: multiple aspects at all ages]. PMID- 6911805 TI - [Can psychiatric emergencies be classified?]. PMID- 6911808 TI - [Aggressiveness in children]. PMID- 6911810 TI - [Aggressiveness in adolescents]. PMID- 6911809 TI - [Introduction to concepts of aggressive behavior and aggressiveness]. PMID- 6911811 TI - [Factors favoring aggressiveness]. PMID- 6911812 TI - [Aggressiveness in health care institutions: nurse-patient relations]. PMID- 6911813 TI - [Aggressive behavior. The case of Natacha]. PMID- 6911814 TI - [Normal aggressiveness]. PMID- 6911815 TI - [Anorexia, the thin people]. PMID- 6911816 TI - [Obesity]. PMID- 6911817 TI - [Bad habits....serious behavior problems]. PMID- 6911818 TI - [Nutrition disorders in schizophrenics; 2 concrete cases. The case of Miss L... The case of Madame X...]. PMID- 6911819 TI - [Feeding behavior: symptomatology]. PMID- 6911820 TI - [Excretory behavior: symptomatology]. PMID- 6911821 TI - [A clinical case of enuresis]. PMID- 6911822 TI - [Enuresis in childhood, clinical study and practical management]. PMID- 6911823 TI - [Pathological aggressive behavior in adults - auto-aggression]. PMID- 6911824 TI - [Pathological aggressive behavior in adults - hetero-aggression]. PMID- 6911825 TI - [Professional education of health care personnel of the psychiatric sector]. PMID- 6911826 TI - [Outline of the clinical practice of a district]. PMID- 6911827 TI - [Regionalization: continuity of care and work team]. PMID- 6911828 TI - [District psychiatry at the general hospital]. PMID- 6911829 TI - [District psychiatric team functioning in a general hospital]. PMID- 6911830 TI - [Extra-hospital practice of the sector]. PMID- 6911831 TI - [District practice and... psychiatric hospital]. PMID- 6911832 TI - [Part-time hospitalization and district activities]. PMID- 6911833 TI - [Education of the nurse of the psychiatric district]. PMID- 6911834 TI - [The dangerous mental patient and the responsibility of the patient care team]. AB - Imprints indicating possible direct inner sensory cell hair contact with the tectorial membrane were observed in the cochlea of a 77-year-old women under a scanning electron microscope (SEM). The imprints were seen in the lower and upper basal cochlear turns but not in the apical and middle turns. The small dot of imprints numbered from a few up to 12 and were arranged in various forms rather than straight lines. Contact between the tectorial membrane and inner and outer sensory cell hairs of the human cochlea was discussed from the SEM findings found in this case. PMID- 6911835 TI - [The team of the psychiatric sector]. PMID- 6911836 TI - [Psychologist, psychiatrist, psychoanalyst]. PMID- 6911837 TI - [Indications and contra-indications for psychoanalytic therapy]. PMID- 6911838 TI - [Psychoanalytically inspired psychotherapy]. PMID- 6911839 TI - [Psychoanalysis and psychotherapy related to psychoanalysis]. PMID- 6911840 TI - [Indications for psychoanalytic psychotherapy in children and adolescents]. PMID- 6911841 TI - [A brief introduction to analytic psychodrama]. PMID- 6911843 TI - [Antidepressive drugs]. PMID- 6911842 TI - [Psychiatrist or psychoanalyst? An unfounded problem]. PMID- 6911844 TI - [Lithium]. PMID- 6911845 TI - [Psychotropic agents, a therapeutic tool one must know how to use]. PMID- 6911846 TI - [Combinations and interactions in psychopharmacology]. PMID- 6911847 TI - [Nursing care and chemotherapy]. PMID- 6911848 TI - [Psychotropic drugs. Introduction]. PMID- 6911849 TI - [Hypnotics]. PMID- 6911850 TI - [Intravascular coagulation in paroxysmal nocturnal hemoglobinuria]. PMID- 6911851 TI - [Infant nutrition: international research, market guide and control policy]. PMID- 6911852 TI - [Instructors in social and health occupations in extension schools]. PMID- 6911854 TI - [Patients and their right to participate in decision making]. PMID- 6911853 TI - [Are small hospitals hazardous?]. PMID- 6911855 TI - [Student subject in care of the aged: promotion of new attitudes]. PMID- 6911856 TI - [Empirical dictatorship in nursing education?]. PMID- 6911857 TI - [Communication and understanding of culture]. PMID- 6911858 TI - [Drugs in migraine. I. Treatment of individual attacks]. PMID- 6911859 TI - [Organization's decision making process; district groups' and permanent committees' voting rights]. PMID- 6911860 TI - [Nursing in primary health care]. PMID- 6911861 TI - [NSFs (Norwegian Nurses' Association) goals and function]. PMID- 6911862 TI - [Practical instruction: experiences from different forms of practical teaching in the Deaconess House Nursing College]. PMID- 6911863 TI - [Cancer nursing: report from the 2nd International Congress]. PMID- 6911864 TI - [Hospital and economics: crisis - or adjustment problems? Summary of our discussion]. PMID- 6911865 TI - [Educational branch orientation: study direction for social and health professions in extended schools]. PMID- 6911866 TI - [Job in developing countries? Think before you go!]. PMID- 6911867 TI - [After a pioneer year in Bergen: 18 pass an examination in nursing science]. PMID- 6911868 TI - [Records--also important for patients]. PMID- 6911869 TI - [Operating room and anesthesia nurses]. PMID- 6911870 TI - [Needs and demands]. PMID- 6911871 TI - [Geriatric nursing: critical perspectives on the science-oriented direction]. PMID- 6911872 TI - [Kidney failure - and dialysis department in Stavanger]. PMID- 6911874 TI - [Children's culture in child education]. PMID- 6911875 TI - [Renewal of nursing organization]. PMID- 6911873 TI - [Day care parents: an analysis of parents' answers and questions concerning goal influences and education]. PMID- 6911876 TI - [Planning of nursing care instruction in Umea]. PMID- 6911877 TI - [The soul is found in blood: Jehovah's Witnesses and blood]. PMID- 6911878 TI - [Equality between men and women]. PMID- 6911879 TI - [Smoking and poor working environment, both a menace to the employee's health. Interview by Sven Stahl]. PMID- 6911880 TI - [Children - violence in amusement - commercialism]. PMID- 6911881 TI - [Variant child health care]. PMID- 6911882 TI - [Ambulance first aid assistance in the first hour]. PMID- 6911883 TI - [Disclosing the truth: possibilities and risks]. PMID- 6911884 TI - [Nurses and medical students]. PMID- 6911885 TI - [The old Palestine or present-day Israel!]. PMID- 6911886 TI - [Breast saving therapy in operable breast carcinoma]. PMID- 6911887 TI - [A practical method for the scheduling of services in health care]. PMID- 6911888 TI - [My schizoid career]. PMID- 6911889 TI - [A patient with toxic epidermal necrolysis. Nutrition]. PMID- 6911890 TI - [Nursing and care of a patient with toxic epidermal necrolysis (Lyell's syndrome)]. PMID- 6911891 TI - [A patient with toxic epidermal necrolysis. Reverse isolation]. PMID- 6911892 TI - [A patient with toxic epidermal necrolysis. Guidance]. PMID- 6911894 TI - [The 'team' and 'zero-load']. PMID- 6911895 TI - [People-oriented care - starting point for nursing competence development. I]. PMID- 6911893 TI - ['But that's no longer necessary nowadays?!']. PMID- 6911896 TI - [Hospital hygiene, what does the hygienist do about it?]. PMID- 6911897 TI - [Terminal home care]. PMID- 6911898 TI - Possible role of prekallikrein in the mechanism of labor. AB - From the standpoint of labor mechanism, behavior of prekallikrein, a kinin forming enzyme, during pregnancy and labor has been of great importance. Plasma prekallikrein determined by synthetic chromogenic tripeptide substrate was increased with advancing gestational ages, reaching approximately 200% of normal. When labor started, it decreased rapidly to 70%, then returned gradually to the normal level after delivery. Prekallikrein and kininogen are only two plasma proteins which change so markedly during labor among many plasma proteins. Role of prekallikrein in the mechanism of labor is presumptively as follows: (1) Prekallikrein is converted to kallikrein resulting in its consumption and decrease. (2) Kallikrein contributes to uterine contraction by liberating kinin from kininogen. PMID- 6911900 TI - Guest editorial: personal observations on the Statewide Study of Nursing and Nursing Education (SSNNE). PMID- 6911899 TI - Comparative study of the action of purified scorpion toxin (tityustoxin) on the submandibular and parotid glands of the rat. PMID- 6911901 TI - Legal ledger. PMID- 6911902 TI - Test your knowledge: the management process in nursing. PMID- 6911904 TI - Diabetic student blocked at OR door what do you think? PMID- 6911903 TI - When the patient is the President. PMID- 6911905 TI - Diane Robinson: nurse and student. Interview by Ann Caputo. PMID- 6911906 TI - The marking behaviors of cats. PMID- 6911907 TI - Hepatic function test--2. Bilirubin metabolism, bromsulphalein (BSP) excretion test. PMID- 6911908 TI - Swimming-puppy syndrome in a litter of German Shepherd pups. PMID- 6911909 TI - Strychnine poisoning in dogs: sources and availability. PMID- 6911911 TI - Intervertebral disc syndrome in a domestic ferret. PMID- 6911910 TI - Epileptic seizures controlled with paramethadione/primidone. PMID- 6911912 TI - Streptococcus zooepidemicus as the cause of septicemia in racing greyhounds. PMID- 6911913 TI - Feline bladderworm. PMID- 6911915 TI - Modified Kirschner splints for application to small birds. PMID- 6911914 TI - Malignant gastric ulcer associated with adenocarcinoma of the gastric fundus in a dog. PMID- 6911917 TI - A comparison of two antibiotics in treating Mycoplasma pneumonia in swine. PMID- 6911916 TI - Using jet injection to vaccinate mink and ferrets against canine distemper, mink virus enteritis, and botulism, type C. PMID- 6911918 TI - Dermatitis induced by diesel fuel on dairy cows. PMID- 6911919 TI - The effectiveness of ivermectin for reducing bovine gastrointestinal helminthiasis. PMID- 6911920 TI - Septic arthritis in a foal with failure of passive transfer. PMID- 6911921 TI - Treatment of infertility in the mare with fluprostenol. PMID- 6911922 TI - Tetralogy of Fallot in a quarter horse foal. PMID- 6911923 TI - What to do when your practice partner dies. PMID- 6911924 TI - A veterinarian's guide to the media. PMID- 6911925 TI - WSNA President's Address to the 1981 House of Delegates. PMID- 6911926 TI - The 80's: decade of decision--time for action. PMID- 6911927 TI - Political involvement in the 80's? What is your decision! PMID- 6911928 TI - Speed of response and oxygenation in healthy aged. PMID- 6911929 TI - Goals for geriatric nursing: barriers to their achievement and proposed solutions. PMID- 6911930 TI - Nursing challenges for change in the 1980's. PMID- 6911931 TI - Quality assurance in the community health nursing setting: getting started. PMID- 6911933 TI - Campaign for pro-life amendment to the constitution. PMID- 6911932 TI - Unity, authority, accountability--nursing imperatives for the 80's. PMID- 6911935 TI - [Karolinska Hospital: decision is taken--County Council takes over]. PMID- 6911934 TI - [Comprehensive health care is also a nurse's function]. PMID- 6911936 TI - [Pool nurses protest deteriorated working environment]. PMID- 6911937 TI - [Negligence in the treatment of a patient with interruption of pregnancy]. PMID- 6911938 TI - [Fire in Beckomberg Hospital in Stockholm: a practice in coordination]. PMID- 6911940 TI - [MBA-KL actions incomprehensible but it is a question of how we have it on the job]. PMID- 6911939 TI - [A professional 'No' to illness compensation]. PMID- 6911941 TI - [Team work and professional role 2 important goals for hospital managers in the course]. PMID- 6911942 TI - [Questionable negligence in treatment at hospital]. PMID- 6911943 TI - [Everyone takes part in purchasing activities]. PMID- 6911944 TI - [A strike in primary health care for the first time]. PMID- 6911946 TI - [Increased need for control of medical equipment]. PMID- 6911945 TI - [Nurse in psychiatry; no bed of roses]. PMID- 6911948 TI - [Generalization of stoma dressings in Vardfacket]. PMID- 6911947 TI - [Alice Lindstrom: a nurse who became education advisor. Interview by Viveka Holmertz]. PMID- 6911950 TI - [Meaningful employment provides good nursing care]. PMID- 6911949 TI - [What can we offer you for the night?]. PMID- 6911952 TI - [I urge all women to donate breast milk]. PMID- 6911953 TI - [Ulla-Britta Palsson, regional representative: she is seldom idle but is happy just the same. Interview by Viveka Holmertz]. PMID- 6911951 TI - [Unemployment occurs in nursing threatened by personnel with basic education]. PMID- 6911954 TI - [Accidents - emergencies: it is important for Anna to have her bag]. PMID- 6911955 TI - [India "exports" nurses from the Middle East - receiving oil in return]. PMID- 6911957 TI - [Broken disposable articles should be reported]. PMID- 6911956 TI - [SHSTF on additional education: study times are short-inservice training and education are also needed]. PMID- 6911958 TI - [Gunnie is the support and help for foreign nurses. Interview by Elisabeth Magnusson]. PMID- 6911960 TI - [Spri (Health Care Planning and Rationalization Institute)-project shows that way: now staff mobility will be reduced in Stockholm's hospital]. PMID- 6911959 TI - [Polish Teresa relates her experiences in Goteborg. Interview by Elisabeth Magnusson]. PMID- 6911961 TI - [Continued over-occupation: 4 days stopping of admissions did not help]. PMID- 6911962 TI - [M.A.R. (Main assistant Robot)-dream remains a real nightmare - a story about the future]. PMID- 6911963 TI - [Wage earners' funds: TCO-discussion about individual profits]. PMID- 6911964 TI - [Unnecessary to have an annual physical examination]. PMID- 6911966 TI - [Alleged mistreatment of relative]. PMID- 6911967 TI - [Spri-project: less personnel in the future]. PMID- 6911965 TI - [Offensive comments in treatment of patient]. PMID- 6911968 TI - [Great changes in new, independent Zimbabwe: one kind of health care for everyone - without regard for skin color]. PMID- 6911969 TI - [Foreign personnel must complete their education - but how?]. PMID- 6911970 TI - [Swedish nurses in Vietnam: hospitals far too advanced]. PMID- 6911971 TI - [Study in an infection ward in the isolation hospital in London]. PMID- 6911972 TI - [Ebba-Lena - one of those affected: County Council saves money - takes away from continued education]. PMID- 6911973 TI - [Profile: Anna Erkki. Interview by Jan Thomasson]. PMID- 6911974 TI - [HS 90 will provide guidelines for future health care and nursing services]. PMID- 6911975 TI - [Education and challenge of other group problems; nevertheless optimism at the prospect of the future is great]. PMID- 6911976 TI - [We want to preserve as much of the manual work as possible]. PMID- 6911977 TI - [Health services in Vietnam: surveillance assistance and trends]. PMID- 6911978 TI - [Membership influence, cooperation with others, LO-SAF control - this is Bjorn Rosengren's opinion about the annual wage negotiations. Interview by Jan Thomasson]. PMID- 6911979 TI - [Contract votes should not be a mere formality. Interview by Viveka Holmertz]. PMID- 6911980 TI - [Risk of unemployment in the medical assistants' group]. PMID- 6911981 TI - [When you are injured on the job - who has the responsibility?]. PMID- 6911982 TI - [Here we are, just like a club]. PMID- 6911983 TI - [Negligent treatment of patient with general complaints]. PMID- 6911984 TI - [Questionable neglect by health personnel]. PMID- 6911985 TI - [Injury in connection with intubation]. PMID- 6911986 TI - [Health services expand in Vietnam but food is still more important]. PMID- 6911987 TI - [The effect of highly purified swine pancreatic kallikrein on sperm motility after cryopreservation]. AB - The effect of kallikrein on sperm motility in cryopreserved ejaculates was investigated. The study was productive of the following results: 1. Cryopreservation of ejaculates is followed by a significant loss of sperm motility. 2. Kallikrein is not effective when added to the ejaculates before cryopreservation. 3. Incubation of cryopreserved ejaculates with kallikrein (5 KU) and serum after thawing significantly inhibits the loss of motility due to cryopreservation in case the initial motility is normal or moderately reduced. Kallikrein is ineffective on sperm motility in ejaculates with low initial sperm motility. PMID- 6911988 TI - [The relevance of serum-complement factors in chronic obstructive pulmonary disease (author's transl)]. AB - In a search for host factors predisposing for chronic obstructive pulmonary disease we have correlated in 20 patients the function of complement with the findings in functional lung exploration. Thereby we found no interrelationship between these two biological parameters. PMID- 6911989 TI - The effects of feminism on the nursing profession. PMID- 6911990 TI - Economics of health care. PMID- 6911991 TI - Ellagic acid and APTT. PMID- 6911992 TI - The shortage of hospital nurses: a new perspective. PMID- 6911993 TI - Gruentzig answers questions about PTCA. Interview by Purcell and Griffin. PMID- 6911994 TI - The choice. PMID- 6911995 TI - VD to STD: redefining venereal disease. PMID- 6911996 TI - Venipuncture and problem veins. PMID- 6911997 TI - What patients really want to know. PMID- 6911998 TI - Benign breast disorders. PMID- 6911999 TI - Screening for early detection. PMID- 6912000 TI - Motivating bse. PMID- 6912001 TI - A breast counseling service. PMID- 6912002 TI - Postbiopsy care. PMID- 6912003 TI - Dealing with feelings: overcoming guilt and worry. PMID- 6912004 TI - ICN '81. PMID- 6912005 TI - School nurse practitioners on the job. PMID- 6912006 TI - A viewpoint on school nursing. PMID- 6912008 TI - Dilemmas in practice: deciding to blow the whistle. PMID- 6912007 TI - Drug data: antineoplastic drugs. PMID- 6912009 TI - Profile. Sue Roberts: "Flying samaritan' to Mexico's rural poor. PMID- 6912010 TI - [Kallikrein test]. PMID- 6912011 TI - Nurses assist injured at Hyatt disaster. PMID- 6912013 TI - Discuss reactions to disaster: nurses address session for Hyatt survivors. PMID- 6912014 TI - Suggestions to promote nursing offered at Forum. PMID- 6912012 TI - Forum endorses economics, practice as priorities. PMID- 6912015 TI - Reconciliation Bill completed, budget battle continues. Capital commentary. PMID- 6912016 TI - Sudan President visits ANA, describes nursing in her country. PMID- 6912017 TI - Retaining experienced nurses is key to quality care. PMID- 6912019 TI - Supreme Court ruling may make women a little more equal. PMID- 6912018 TI - [Electron microscopic study of the effect of methicillin on phagocytized Staphylococcus aureus cells]. AB - Morphological changes in phagocytized cells of Staph. aureus due to methicillin were studied with electron microscopy of ultrathin sections. Peritoneal macrophages of mice obtained by excitation of the abdominal cavity with medium No. 199 followed by infection with 1-milliard staphylococcal suspension were tested. Methicillin was administered in single doses of 2.5, 5, 25 and 50 mg/kg. The doses of 2.5 and 5 mg/kg induced specific changes in some cells. First of all the division septa were affected. After that the cell walls became thinner the cells increased in size, the cytoplasm became electronically less solid. No lysed cells were detected. The use of the doses of 25 and 50 mg/kg entailed polymorphism of the damages. Perforations formed in the bacterial cell wall. The cytoplasm acquired a characteristic granular structure evident of the cell death. With an increase in the dose from 25 to 50 mg/kg no rise in the level of the morphological changes in the bacterial cells was noted. Determination of methicillin concentration in the peritoneal exudate showed that it was 2--4 times higher depending on the dose than the MIC in vitro. PMID- 6912020 TI - Myths and facts about nursing baccalaureates. PMID- 6912021 TI - OR nursing care of cancer patients. PMID- 6912022 TI - Hemostasis: a balanced system. PMID- 6912023 TI - Computer support for a case cart system. PMID- 6912024 TI - Endoscopic movies for patient teaching. PMID- 6912025 TI - Standards of administrative nursing practice: OR. PMID- 6912027 TI - Careful analysis needed for breast cancer risks. PMID- 6912026 TI - Anesthesia for outpatient surgery. PMID- 6912028 TI - OR nurses can meet challenges to their purchasing power. PMID- 6912029 TI - Patient representatives come to the operating room. PMID- 6912030 TI - A change to primary care in day surgery. PMID- 6912031 TI - The patient as colleague: a personal philosophy. PMID- 6912032 TI - Accountability for the sexual awareness of the spinal cord injured patient. PMID- 6912033 TI - Tough training - and then a grass-roots background. PMID- 6912034 TI - The nurse and the law. Drugs draw judicial fire. PMID- 6912035 TI - Drugs used in the treatment and prophylaxis of malaria. The Royal Melbourne Hospital Pharmacy Department. PMID- 6912036 TI - Throwing a light on neonate jaundice. PMID- 6912037 TI - Don't laugh--this is serious. PMID- 6912038 TI - The right to a 'good death'. PMID- 6912039 TI - The role of accountability in nursing of the future. PMID- 6912040 TI - The evaluation stage of the nursing process. PMID- 6912041 TI - The nurse & the law: drugs, and the need for systems. Part II. PMID- 6912042 TI - Metronidazole. PMID- 6912043 TI - Bathurst Island maternity care. PMID- 6912044 TI - The education and practice of midwives in New Zealand. PMID- 6912045 TI - Preparing for childbirth the yoga way. PMID- 6912046 TI - The nutritional and immunological benefits of breast milk. PMID- 6912047 TI - Childbirth in remote Papua New Guinea. PMID- 6912048 TI - Alternative birth centre: geography or a philosophy? PMID- 6912049 TI - Reconstructing the model. PMID- 6912050 TI - A cool view of the "midwife debate". PMID- 6912051 TI - Industrial desk: a lecturer in industrial relations. PMID- 6912052 TI - Tempo of the 80's: visions and challenges. PMID- 6912053 TI - Learning about myself. PMID- 6912054 TI - How to keep fit and trim. PMID- 6912055 TI - Aiming for better health in Darwin. PMID- 6912056 TI - Side effects of vaccines: cows milk and cancer. PMID- 6912057 TI - Riddle me, riddle me, from my bellyache I flee. PMID- 6912058 TI - Standards of care. PMID- 6912059 TI - Sexuality and contraception. PMID- 6912060 TI - The physiology of lactation. PMID- 6912061 TI - Consumer expectations. PMID- 6912062 TI - Homebirth. PMID- 6912063 TI - Hospital accreditation: its implications for midwives. PMID- 6912064 TI - It is life or death? PMID- 6912065 TI - Tumor mitochondrial transfer RNAs: the nucleotide sequence of mitochondrial tRNALeuUAG from Morris hepatoma 5123D. PMID- 6912066 TI - Crystallization and identification of a binary complex of a elastase-I and a carboxypeptidase A gamma from porcine pancreas. PMID- 6912067 TI - Isoaccepting tRNAs of posterior silkgland of mutant Bombyx mori. PMID- 6912068 TI - Characterization and origin of immunoreactive glandular kallikrein in rat plasma. PMID- 6912069 TI - Reactivity of human leukocyte elastase and porcine pancreatic elastase toward peptide 4-nitroanilides containing model desmosine residues. Evidence that human leukocyte elastase is selective for cross-linked regions of elastin. AB - Elastin contains a number of cross-linking amino acid residues such as desmosine and isodesmosine which are primarily hydrophobic in character, but have a positively charged pyridinium ring. These cross-linking residues are formed by the action of lysyl oxidase upon Lys residues in tropoelastin, a precursor of elastin. A series of tetrapeptide 4-nitroanilides which contain Lys and a series of modified lysine residues were synthesized. The modified lysine residues [epsilon-carbobenzyloxy (Z), epsilon-benzoyl (Bz), epsilon-benzimidoyl (Bim), and epsilon-2-picolinoyl (Pic)] have various characteristics of desmosine and isodesmosine residues, such as a positive charge, a hydrophobic aromatic ring, or a pyridine ring. The reactivity of the tetrapeptide 4-nitroanilides containing the model desmosine residues at P4, P3, or P2 with human leukocyte (HL) and porcine pancreatic (PP) elastase was measured at pH 7.5 and 25 degrees C. HL elastase exhibited high reactivity toward the substrates with P4 or P3 hydrophobic groups (Z, Bz, or Pic), and MeO-Suc-Lys(Pic)-Ala-Pro-Val-NA is 7 times more reactive than the previous best HL elastase substrate, MeO-Suc-Ala-Ala Pro-Val-NA. The major change occurred in KM values. The substrates containing Lys residues were either nonreactive or poor. Except for two substrates with P2 hydrophobic residues (Bz and Pic), PP elastase was less reactive toward the substrates containing model desmosine residues than toward MeO-Suc-Ala-Ala-Pro Val-NA. The data support the hypothesis that HL elastase cleaves elastin selectively ner cross-linking residues. The results also indicate that HL elastase binds tightly to these regions and would be poorly effective toward regions of elastin or tropoelastin which contain Lys residues. PMID- 6912070 TI - The effects of vanadate on calcium transport in dialyzed squid axons. Sidedness of vanadate-cation interactions. AB - (1) Vanadate (VO3-) fully inhibits the ATP-dependent uncoupled Ca efflux (Ca pump) in dialyzed squid axons. (2) Vanadate inhibits with high affinity. The mean apparent affinity (K 1/2) obtained was 7 microM. (3) Inhibition by vanadate is dependent on Cao. External Ca lead to a release of the inhibitory effect. (K 1/2 congruent to 3 mM). This antagonistic effect can be reverted by increasing the vanadate concentration. Internal K+ increases the affinity of the intracellular vanadate binding site. External K+ has no effect on the inhibition. (4) Vanadate has no effect on the Nao-dependent Ca efflux component (forward Na-Ca exchange) in the absence of ATP. In axons containing ATP vanadate modified this component. PMID- 6912071 TI - Vanadate-stimulated NADH oxidation in plasma membrane. AB - The rate of NADH oxidation with oxygen as the acceptor is very low in mouse liver plasma membrane and erythrocyte membrane. When vanadate is added, this rate is stimulated 10- to 20-fold. The absorption spectrum of vanadate does not change with the disappearance of NADH. The reaction is inhibited by superoxide dismutase, and there is no activity under an argon atmosphere. This indicates that oxygen is the electron acceptor and the reaction is mediated by superoxide. The vanadate stimulation is not limited to plasma membrane. Golgi apparatus and endoplasmic reticulum show similar increase in NADH oxidase activity when vanadate is added. The endomembranes have significant vanadate-stimulated activity with both NADH and NADPH. The vanadate-stimulated NADH oxidase in plasma membrane is inhibited by compounds, which inhibit NADH dehydrogenase activity: catechols, anthracycline drugs and manganese. This activity is stimulated by high phosphate and sulfate anion concentrations. PMID- 6912072 TI - Factor requirements for the tritin inactivation of animal cell ribosomes. AB - Wheat germ contains (tritin) that efficiently inhibits protein synthesis in cell free extracts from animal cells but not from wheat germ. Tritin has been purified to apparent homogeneity and shown to block enzymatically polypeptide chain elongation. We have extended these studies to examine more closely then mechanism of tritin inactivation of animal cell ribosomes. Here we provide evidence suggesting that ATP and tRNA, previously though to be tritin co-factors, function in the inhibition by altering the conformation of the ribosome to a form susceptible to tritin attack. Tritin treatment does not inhibit the binding of aminoacyl-tRNA to ribosomes, but it does partially reduce the ribosome binding of elongation factor 2. Tritin inhibition appears to affect the core ribosome and not ribosome-associated factors. However, the core ribosome itself is not a suitable substrate for tritin attack; a factor(s) is removed from ribosomes by high salt washing which is required for the tritin-induced inhibition. The ability to be inhibited is restored when ascites cell core ribosomes are supplemented with factors from either ascites cells or wheat germ. In contrast, neither ascites cell factors nor wheat germ factors will promote a significant tritin-induced inhibition of core ribosomes from wheat germ. This indicates that the specificity of tritin inhibition resides primarily at the level of eukaryotic core ribosome. PMID- 6912074 TI - The kallikrein-kinin pathway in psoriasis. Preliminary observations. PMID- 6912073 TI - Mechanism of aminoacylation of tRNA. Influence of spermine on the kinetics of aminoacyl-tRNA synthetases by isoleucyl- and valyl-tRNA synthetases from Mycobacterium smegmatis. AB - Isoleucyl-tRNA synthetase has been purified to homogeneity from Mycobacterium smegmatis. The influence of spermine on the kinetics of valyl-tRNA and isoleucyl tRNA formation has been investigated by Cleland's method (Cleland, W.W. (1963) Biochim. Biophys. Acta 67, 104-137, 173-187, 188-196). The results suggest that in the presence of spermine and suboptimal concentration of Mg2+, the formation of valyl-tRNA and isoleucyl-tRNA follows a sequential mechanism. In the presence of an optimal concentration of Mg2+, both valyl-tRNA and isoleucyl-tRNA formation proceeds by a ping-pong mechanism. However, in the presence of spermine and optimal concentrations of Mg2+, valyl-tRNA formation follows the ping-pong mechanism while isoleucyl-tRNA formation follows the sequential mechanism. PMID- 6912075 TI - [Participation of the lungs in regulating the activity of the kallikrein-kinin system during immobilization stress]. AB - Experiments on rats have shown that during immobilization stress, there takes place an intense activation of the kallikrein-kinin system (KKS). The control animals do not show arteriovenous difference in the KKS values. Study of the time course of immobilization stress has demonstrated changes in the KKS values attesting to the system activation seen only in venous blood in the early stages of immobilization. With time activation of the kinin system is also seen in arterial blood, and by 24 hours of immobilization the arteriovenous difference disappears. Thus the arteriovenous difference in the KKS values, which occurs during immobilization stress indicates the compensatory role of the lungs in the early stages of immobilization. PMID- 6912076 TI - Treatment re-entry and outcomes of opioid addicts during a four-year follow-up after drug abuse treatment in the United States. AB - Post-treatment outcome measures during a four-year follow-up period were examined in relation to readmissions to drug abuse treatment. The sample included 1,174 opioid addicts admitted during 1972-1973 to 26 different treatment programmes throughout the United States that participated in the Drug Abuse Reporting Program (DARP). Admissions to methadone maintenance programmes, therapeutic communities, outpatient drug-free treatments, and outpatient detoxification programmes were studied, as well as a comparison group which completed admission procedures but did not return for treatment at the DARP agency. The examination of temporal patterns of treatment and outcome indicators presenting drug use, criminality, and productive activities during the four-year follow-up period showed that there were beneficial effects associated with treatment. PMID- 6912077 TI - Intervention approaches for rural opium users. AB - The rate of addiction among adults in the opium-growing areas of South East Asia and the Middle EAst varies between 3 per cent and 10 per cent. Supply-reduction efforts alone have rarely been successful and programmes aimed concurrently to reduce demand are now being initiated. Primary health care is considered a prerequisite for the success of demand-reduction programmes and includes the training of primary health care workers to assist in prevention programmes as well as in the treatment and rehabilitation of addicted persons. This supply demand-reduction approach will require careful evaluation of its effectiveness. PMID- 6912078 TI - Drug consumption among the student population of Mexico City and its metropolitan area: subgroups affected and distribution of users. AB - The results of a survey based on a sample of 4,059 students attending intermediate and upper intermediate schools in Mexico City and its metropolitan area showed that the percentage of drug use "ever" by substance was the following: alcohol, 59; tobacco, 53.2; inhalants, 5.4; cannabis, 3.8; tranquilizers, 3.1; amphetamines, 2.7; sedatives, 1.3; opium, 0.91; LSD, 0.54; cocaine, 0.52; heroin, 0.29. Of the students reporting use "ever", the percentage reporting use of one of these substances "in the past months" ranged from 22.5 to 58.3. While there were more female students among the users of tranquilizers and stimulants, male students predominated among the users of other substances, with the difference being most pronounced among cannabis users. Older students were more involved with cannabis; in contrast, inhalants were more popular with younger students. The use of other substances varied little with age. Use of alcohol and cannabis was also most frequent among students of schools in middle, upper middle and upper class areas, whereas use of inhalants was most common among students attending schools in lower class areas. PMID- 6912079 TI - Drug use among young people in Lagos, Nigeria. AB - This paper presents the results of two studies on drug abuse carried out among young people. One study included a sample of 2,846 pupils from 17 secondary schools in Lagos, the other 300 patients admitted to the Lagos University Teaching Hospital for treatment of drug abuse. Among the secondary school students the major substances used were alcohol, barbiturates, central nervous system stimulants, tobacco, Mandrax and cannabis. The majority of hospital patients treated for drug abuse were cannabis users. PMID- 6912080 TI - Observations on cannabinoid content in Cannabis sativa L. grown in Tuscany, Italy. AB - The paper summarizes the analytical results on 114 Cannabis sativa L. samples seized in Tuscany. The percentage of delta 9-tetrahydrocannabinol content in adult plants and the phenotype ratio of young plants were determined to differentiate fibre-type from drug-type cannabis plants. The analysis revealed that 71.9 per cent of the total sample were cannabis plants of a drug type. PMID- 6912081 TI - Effects of human granulocyte elastase on fibrinolysis. PMID- 6912082 TI - Everything you want to know about teeth but were afraid to ask. PMID- 6912083 TI - Sugar--guilty or not guilty? PMID- 6912084 TI - Teeth sheet. PMID- 6912085 TI - New, new, new! Sheffield, Leicester, Hull, Maidstone. PMID- 6912087 TI - Feet sheet with older people in mind. PMID- 6912086 TI - Foot care - with older people in mind. PMID- 6912088 TI - Conference: special for HVs. PMID- 6912089 TI - Conference: special for district nurses. PMID- 6912090 TI - The process of Little Red Riding Hood. PMID- 6912091 TI - Incontinence - an individual approach. PMID- 6912092 TI - Anaphylaxis. PMID- 6912093 TI - Adult respiratory distress syndrome. PMID- 6912094 TI - Distribution, subcellular localization and identity of immunoreactive alpha melanotropin in the pituitary gland and brain. AB - In homogenates of adult human or rat hypothalamic tissue, immunoreactive alpha MSH (alpha-MSHi) is concentrated in synaptosomes, suggesting that it is localized in neurons. This conclusion is supported by immunohistochemical results on the localization of alpha-MSHi in the brain. The function of alpha-MSHi in the hypothalamus is undefined but the amount of alpha-MSH in this tissue increases in young rats and decreases in old rats. There is little alpha-MSHi in pituitary glands from human abortuses before the 15th gestational week. Thereafter the amount of alpha-MSHi in the anterior and neurointermediate lobes increases appreciably. When acetic acid extracts of each lobe were analysed by high pressure liquid chromatography the alpha-MSHi in extracts of the anterior lobe had a retention time equal to that of desacetyl alpha-MSH; little if any alpha MSHi had a retention time identical to that of desacetyl alpha-MSH; alpha-MSH, if present in these extracts, appeared to be a minor component. A similar analysis of extracts of adult human hypothalamic tissue yielded results suggesting that the alpha-MSHi in this tissue is also attributable largely to desacetyl alpha MSH. PMID- 6912095 TI - Biological role of the pars intermedia in lower vertebrates. AB - The most obvious function of the pars intermedia in lower vertebrates is the secretion of melanocyte-stimulating hormone (MSH) for the purpose of pigmentary control. In some amphibia, elasmobranchs and teleosts, the histological study of the pars intermedia, the radioimmunoassay of pituitary and plasma MSH and the effects of hypophysectomy and of MSH injection suggest that the activity of the pars intermedia is regulated to satisfy the needs of cryptic colour change. MSH secretion is associated with dispersion of melanin granules and with melanogenesis. However, in other teleost species, both the evidence from pituitary cytology and the failure to respond to MSH injection suggest that pigmentary change is not regulated by changes in the plasma titres of MSH. Results discussed here indicate that MSH alone may be inadequate for pigmentary control. Evidence for non-pigmentary functions of the pars intermedia is circumstantial and fragmentary. It is based on cytological observations of altered pars intermedia activity under certain conditions, and on observations of physiological changes that accompany increased melanotropic activity. Such function include effects of plasmas titres of cortisol in teleosts, resistance to adrenaline-induced hyperglycaemia in toads, and effects on neural activity in fish and amphibia. Evidence for pars intermedia involvement in osmoregulation is briefly discussed. PMID- 6912096 TI - Melanocyte-stimulating hormone and adaptive behaviour. AB - In order to study the physiological role of alpha-MSH in adaptive behaviour, plasma concentrations of alpha-MSH were measured during acquisition and extinction of active avoidance behaviour and during retention of a passive avoidance response. In addition the effect on behaviour of neutralization of centrally available alpha-MSH by intracerebroventricular administration of antisera to alpha-MSH was investigated. Blood samples were collected either before or immediately after each acquisition session and also before and after the extinction session of an active avoidance response. In addition, blood was collected after retention of a passive avoidance response from rats which had been submitted t different shock intensities during the learning trial, resulting in various passive avoidance groups of animals could be found. Neutralization or reduction of available alpha-MSH in the brain by intracerebroventricular administration of antisera to this neuropeptide results in disturbances in active as well as passive avoidance behaviour. This may indicate that alpha-MSH available in the brain plays a physiological role in brain functions involved in adaptive behaviour and in processes related to learning. Thus, at least in some species, MSH manifests its adaptive function predominantly via the brain. PMID- 6912097 TI - The intermediate lobe of the pituitary gland: introduction and background. AB - Research from a number of laboratories using of systems has shown that cells from the anterior and intermediate lobes of the pituitary gland, from hypothalamic neurons and from the placenta produce a glycoprotein with the full sequences of corticotropin, beta-lipotropin and gamma-melanotropin. These peptides in turn contain the sequences of alpha- and beta-melanotropin, CLIP, gamma-lipotropin, alpha-, beta- and gamma-endorphins and methionine-enkephalin. The precursor molecule, here called protropin, is processed by the four types of cell to give rise to different ratios of corticotropin, CLIP, beta- and gamma-lipotropin, alpha-, beta- and gamma-endorphins and alpha-, beta- and gamma-melanotropins. The physiological roles of these peptides in neurotransmission, pre- and postnatal endocrinology, mental disorders and neoplasia are only now being established. PMID- 6912098 TI - Microenvironments in haemopoietic and lymphoid differentiation. PMID- 6912099 TI - Haemopoietic microenvironments in vitro: ultrastructural aspects. AB - Haemopoietically active long-term bone marrow cultures from several species have been investigated ultrastructurally. Human, tree shrew and mouse cultures generally support granulopoiesis, although recently it has been possible to convert a granulopoietic mouse culture to extensive erythropoiesis. The haemopoietic products of the cultures include granulocytes (neutrophil and basophil), mast cells, monocytes, megakaryocytes and all stages of the erythrocytic series. Plasmacytes and occasional lymphocytes have been observed in small numbers in human cultures (possible indicating retention rather than formation). The stromal elements of the adherent layer of these cultures include endothelial cells, reticulum cells, fat cells and fibroblasts. The adherent layers are responsible for the inductive microenvironment within the cultures, and show features specific for the line of differentiation. In the granulocytic cultures there is close association between developing fat cells (reticulum cells) and granulocyte precursors. Endothelial cell monolayers cover large regions of these cultures, and the areas beneath this monolayer are rich in early granulocytes. Mature granulocytes and monocytes migrate through the endothelial layer, demonstrating in vitro "transmural passage". Cultures stimulated for erythropoiesis show a considerable reduction in fat cells, in endothelial cell cover and in the numbers of classical monocytes. Erythropoiesis appears to be promoted by a close association of the entire erythrocytic series with monocytic cells, forming "erythroblastic islets" in vitro. A possible pathway of intracellular communication between differentiating haemopoietic cells and the stromal cells in their microenvironment is suggested. PMID- 6912100 TI - Dialysis and the diabetic patient. PMID- 6912102 TI - Dialysis and the diabetic patient: dietary management. PMID- 6912101 TI - Dialysis and the diabetic patient: basic description and problems. PMID- 6912103 TI - Dialysis and the diabetic patient: psychosocial considerations. PMID- 6912104 TI - Dialysis and the diabetic patient. Personal reflections: the trauma of diabetic renal failure. PMID- 6912105 TI - Living with diabetes and kidney disease: a one-day patient symposium. PMID- 6912106 TI - The diabetes assertiveness test: a measure of social coping skills in pre adolescent diabetics. PMID- 6912107 TI - School visits: an extension of the diabetes education program for children. PMID- 6912108 TI - The disease of familial polyposis: its impact on families. PMID- 6912109 TI - A study of benign intestinal polyps. PMID- 6912110 TI - [Agents and techniques of disinfection of the skin]. PMID- 6912111 TI - An interview with Marylyn McManus and Grace Musi of South Africa, stomatotherapists. Interview by Philip Pressel. PMID- 6912112 TI - Treatment for three ostomy patients with systemic skin disorders: psoriasis, pemphigus, and dermatomyositis. PMID- 6912113 TI - To tell or not to tell? Responses to May-June editorial on ostomate enterostomal therapists. PMID- 6912114 TI - Sexuality and the physically disabled (correction). PMID- 6912115 TI - Cardiac relaxation and myofibrillar interactions with phosphate and vanadate. PMID- 6912116 TI - Aminoacylation of ethionine to rat liver tRNAMet and its incorporation into protein. PMID- 6912117 TI - [Suppurative meningitis]. PMID- 6912118 TI - [Infantile cerebral palsy]. PMID- 6912119 TI - [Acute opisthorchiasis and pregnancy]. PMID- 6912120 TI - [Medical first aid in fractures of the extremities]. PMID- 6912121 TI - [Modern blood substitutes]. PMID- 6912122 TI - [Prevention of leishmaniasis]. PMID- 6912124 TI - [Status of medical care for the population in capitalist and developing countries]. PMID- 6912123 TI - [Parental health education in preschool institutions]. PMID- 6912125 TI - [Work organization and improvement in provincial feldsher councils]. PMID- 6912126 TI - [Incomplete placenta praevia]. PMID- 6912127 TI - [Endometrial precancer and uterine hemorrhage]. PMID- 6912128 TI - [Toxic form of influenza]. PMID- 6912129 TI - [Prevention of postinjection infiltrates and phlegmons]. PMID- 6912130 TI - [Hygiene of massage]. PMID- 6912132 TI - [Injury to the pelvic bones (clinical aspects, diagnosis and prehospital first aid]. PMID- 6912131 TI - [Pyelonephritis in children]. PMID- 6912133 TI - [Diet therapy in arteriosclerosis]. PMID- 6912134 TI - [Pleurisy in children]. PMID- 6912135 TI - [Chronic viral hepatitis in children]. PMID- 6912136 TI - [Acute inflammation of the middle ear in children]. PMID- 6912137 TI - [International activities of the Union of Red Cross and Red Crescent Societies of the USSR]. PMID- 6912138 TI - [Dental enamel hypoplasia in children]. PMID- 6912139 TI - [Characteristics of vitreous body pathology]. PMID- 6912140 TI - [Intestinal invagination]. PMID- 6912141 TI - [Work of ships' feldshers]. PMID- 6912142 TI - [Work experience in making healthier working conditions in industrial enterprises]. PMID- 6912143 TI - [Complete uterine rupture]. PMID- 6912144 TI - [Acute gonorrhea of the female genitalia]. PMID- 6912145 TI - [Sterilization and disinfection of medical devices]. PMID- 6912146 TI - [Hemorrhage into the brain]. PMID- 6912147 TI - [Outline for determining the severity of industrial injuries]. PMID- 6912148 TI - [Interaction of drugs]. PMID- 6912149 TI - [Glomerulonephritis in children]. PMID- 6912150 TI - [Acute herpetic gingivostomatitis in children]. PMID- 6912151 TI - [Management of pregnancy, labor and the puerperal period in cardiovascular system diseases]. PMID- 6912152 TI - [Traumatic chest injuries]. PMID- 6912153 TI - [Spinal fractures]. PMID- 6912154 TI - [Role of the feldsher and midwife in delivering primary medical health care to the population]. PMID- 6912155 TI - [Asepsis problems in the work of hospital and polyclinic surgery wards]. PMID- 6912156 TI - [Snake bites and their treatment]. PMID- 6912157 TI - [Diagnosis and first aid in child poisonings]. PMID- 6912158 TI - [First aid in drowning]. PMID- 6912159 TI - [Multivitamins]. PMID- 6912160 TI - [Health education in cardiovascular diseases]. PMID- 6912161 TI - [Worker interest in health bulletins]. PMID- 6912162 TI - [Postinjection abscesses]. PMID- 6912163 TI - [Use of chloroethyl on an insect bite]. PMID- 6912165 TI - Sunset of the Georgia Nurse Practice Act. PMID- 6912164 TI - Antibiotic treatment of Haemophilus influenzae type B meningitis: the problem of bacterial resistance. PMID- 6912166 TI - [The clinical significance of the unstable bladder (author's transl)]. AB - The anamnestic, clinical and urodynamic findings of 377 consecutively investigated women were evaluated. 86 (23%) patients showed bladder instability. The intensity of involuntary bladder contractions and the occurrence of incontinence in association with involuntary detrusor contractions influenced the clinical significance of unstable bladders. The maximum urethral closure pressure however had no influence on it. Urge incontinence was the most reliable symptom distinguishing those patients with bladder instability. Frequency of micturition, nocturia and nocturnal enuresis were less reliable in this respect. Urinary tract infections showed no correlation to bladder instability. PMID- 6912167 TI - [Prevention of urinary tract infections with a single dose of cotrimoxazole (bactrim forte) in patients with a urinary catheter (author's transl)]. AB - Prevention of urinary tract infections (UTT's) in female patients with postoperative indwelling catheter was investigated by applying a single dose of cotrimoxazole on the day of removal of the catheter, and the results compared to the morbidity from perioperative urinary tract infections in the years 1978-1979. Hence, it was the aim of this open study to establish whether the incidence of postoperative nosocomial UTT'S could be lowered and development of clinical symptoms prevented. Bacteriological problem and the diagnostic value of urinary sediment were also investigated. A single dose of Cotrimoxazole proved to be significantly effective in preventing or treating nosocomial UTT's. Urinary sediment in preventing or treating nosocomial UTT's. Urinary sediment is a simple, cheap and effective screening method for detecting uncomplicated urinary tract infections. However, interpretation of the sediment is doubtful if analysed in the early phase following gynaecological operations. PMID- 6912168 TI - [Colposcopic differential diagnosis of portiopapillomatosis (author's transl)]. AB - The guidelines for differential diagnosis of portiopapillomas were established on the basis of 21 cases. The term "papilloma" is exclusively confined to the changes occurring at the surface of the portio. Two colposcopic criteria of the typical portiopapilloma are defined. These are: 1. the specific surface structure and the reactivity to acid reagents, and 2. the specific vascular architectonics and its ability to react to cyclopeptid hormones. Hence, three architectonic types of papillae and 3 basic types of blood vessels are described. Basing on the guidelines it has become colposcopically possible to differentiate between a benign papillomatous growth and an exophytic carcinoma. The atypical papillomas are described in the concluding section of the article. These are characterized by anomalies of the surface and of the vessels. The epithelial layer of these papillomas often shows dysplastic or even carcinomatous proliferation. PMID- 6912169 TI - [The localization and differential diagnosis of benign and malignant gynaecological tumours in the axial computer assisted tomogram (author's transl)]. AB - 40 computer assisted tomographies of the vagina, the uterus and the ovaries were evaluated. The differential diagnosis between malignant and benign neoplasms is difficult unless there is spread into the soft tissues. The early diagnosis of ovarian neoplasms by axial computer assisted tomography is impossible. We are of the opinion that axial computer assisted tomography should be performed as early as possible in the diagnosis of local recurrences of malignant tumours of the female genital tract. PMID- 6912170 TI - [Anamnesis and findings in 501 women referred to hospital with suspected diagnosis of ectopic pregnancy (author's transl)]. PMID- 6912171 TI - [Ultrasound diagnosis of omphalocele during the first trimester of pregnancy (author's transl)]. AB - Ventral defects in the fetus occur in 1/3200 to 1/10,000 deliveries. Prognosis for the newborn is mostly fatal since these anomalies are frequently combined with other congenital anomalies. A through ultrasound study of the fetus in its longitudinal and transverse diameter permits the antenatal diagnosis of this severe fetal anomaly. The earliest diagnosis of the fetal omphalocele in the first trimester of pregnancy is described in detail in this paper. PMID- 6912172 TI - [Control of IUD-position (author's transl)]. AB - The correct position of an IUD in the uterine cavity is essential for the effectiveness of the method. Ultrasound examination of the thickness of the anterior and posterior wall of the uterus were carried out and their relation to a correct position of the IUD calculated. It was found that the position of the IUD is correct, if the distance between fundus and the cranial end of the IUD does not exceed the thickness of the uterine wall by more than one-third; i. e. in all 4/3 of the thickness. The correlation between the ultrasound results of length, version and flexion of the uterus and complaints and side-effects like bleeding and pain are discussed, especially if the IUD is not in correct position. PMID- 6912173 TI - [Sonographic diagnosis of a placental tumour with high-grade intrauterine foetal development deficiency, increasing anhydramnia and subsequent foetal death (author's transl)]. AB - The article reports on prenatal diagnosis of a large tumour of the placenta (chorioangioma) and, for the first time, on sonographic observation of the course of the disease with intrauterine deficient development of the foetus, increasing oligohydramnia and subsequent intrauterine foetal death. The complications associated with large chorioangiomas, which are well known, with an intrauterine and perinatal mortality of up to 30%, underline the need for timely sonographic diagnosis. Chances of sufficiently early intervention have been created via closely meshed checkup controls. PMID- 6912174 TI - [A new oxytocin infusion rate recorder (author's transl)]. AB - A new oxytocin-infusion rate recorder system is introduced. It provides continuous plotting dosages on the labor channel of the cardiotocogram. So far 82 conductions of labour were monitored with the new system and evaluated for oxytocin overstimulation. The rate of overstimulations could be reduced resulting in better fetal outcome. PMID- 6912175 TI - [Comparative examinations of hysterectomy clamps (author's transl)]. AB - Conventional and recently developed hysterectomy clamps were examined with respect to sure, nonslip grip and minimum resulting tissue trauma. Slippage was appraised by means of the tenacity testing device, tissue damage on the basis of macroscopic, histologic, and scanning-electron-microscope findings. The new clamp (Zeppelin) comes closest to meeting the demands set for sure grip and gentleness to tissue as compared to the conventional clamps (Wertheim, Rogers, Masterson) and best satisfies requirements for the use in hysterectomies today. PMID- 6912176 TI - [Cooper IUD and congenital malformation? (author's transl)]. AB - A 23 year old, gravida O, conceived 18 months following insertion of a copper containing IUD. At 10 weeks; gestation the IUD was removed. At 42 weeks' gestation, an infant was delivered normally, with severe upper limb reduction deformities and other minor malformations. However, reviewing the literature the possible role of the IUD in the etiology of limb reduction deformities cannot be supported. PMID- 6912177 TI - Effects of sodium loading, desoxycorticosterone acetate, and corticosterone on urinary kallikrein excretion. AB - In male Sprague-Dawley rats, changes in kallikrein activity in urine were produced by high sodium intake (1% saline as drinking fluid for 14 days), and administration of desoxycorticosterone acetate (DOCA, 15 mg/kg s.c. for 5 days), and of corticosterone (2 x 0.2 or 2 x 20 mg/kg s.c. daily for 5 days). Salt loading caused a decrease in urinary kallikrein excretion (p less than 0.005), while DOCA produced an increase (p less than 0.001). While corticosterone, administered in the low dose, had no effect on urinary kallikrein excretion, the high dose, given for 5 days, diminished kallikrein excretion to about half the basal value (p less than 0.001). Simultaneously, the excretion of aldosterone decreased to about one third the amount measured in the corresponding control rats. PMID- 6912178 TI - Reduced aminoacylation of asparagine-transfer RNA early in the developmental cycle of Dictyostelium discoideum: modification pattern and possible significance of the uncharged isoacceptor tRNAAsn3. AB - Changes in the patterns of isoacceptors of tRNAAsn and alterations in modification of the guanine residue 34, the first position of the anticodon of tRNAAsn, have been observed in eukaryotes during differentiation. We use Dictyostelium discoideum as a model system to elucidate the possible involvement of tRNAAsn in developmental processes. Vegetative amoebae were induced to undergo developmental transition by nutrient starvation. Since amino acid starvation alone is a specific stimulus initiating development and unacylated tRNAs might be involved in control mechanisms of protein synthesis, the level of aminoacylation of tRNAAsn isoacceptors has been investigated. As early as two minutes after the onset of development, the aminoacylation of tRNAAsn specifically was reduced to about 30%, whereas at the same time 10 other tRNA species were found to be charged normally, i.e. to 70-100%. One of the two major isoacceptors, tRNAAsn3, was completely deacylated, whereas the other one, tRNAAsn2, accounted for the residual aminoacylation. Analyses of the modified nucleosides of highly purified tRNAAsn2 and tRNAAsn3 are respectively, show that both isoacceptors are identical in their modification patterns except for the modification at the first position of the anticodon; tRNAAsn2 comprises queuine (Q), 7-[(4,5-cis-dihydroxy-2 cyclopenten-1-ylamino)methyl]-7-deazaguanine, whereas tRNAAsn3 contains guanine. PMID- 6912179 TI - Cleavage of peptide-4-nitroanilide substrates with varying chain length by human leukocyte elastase. AB - Two series of substrates with the formulas H-Alan-Val-4-nitroanilide and 3 carboxypropionyl-Alan-Val-4-nitroanilide (n = 1, 2 and 3) were synthesized. Elongation of the peptide chain yields increasingly better substrates for human leukocyte elastase both in terms of Km and kcat. These results indicate an extended substrate binding site for the enzyme. PMID- 6912180 TI - [Blood cell count]. PMID- 6912181 TI - [Coproculture: goals--limitations--indications]. PMID- 6912182 TI - [Cardiac physiology]. PMID- 6912183 TI - [General principles of chemical toxicity: methods of poisoning]. PMID- 6912184 TI - [Phobic neurosis]. PMID- 6912186 TI - [Between psychiatry and dementia...being a psychiatric nurse]. PMID- 6912185 TI - [Changes in the blood picture]. PMID- 6912187 TI - [Trial with compressed scheduling]. PMID- 6912189 TI - [Standards of nursing care of the AIIC" an interpretation]. PMID- 6912188 TI - [Social role of medicines]. PMID- 6912191 TI - [The spiritual dimension of nursing care]. PMID- 6912190 TI - [Birth of a child with a malformation]. PMID- 6912192 TI - [Woman's reaction to spontaneous abortion]. PMID- 6912193 TI - The nurse educator: change agent for medical student attitudes. PMID- 6912194 TI - Preparation of nursing students for health care teams. PMID- 6912195 TI - Role, selection and preparation of unit head nurses--I. PMID- 6912196 TI - Birth planning in Cuba: a basic human right. PMID- 6912197 TI - Post-natal care in hospital--time for change. PMID- 6912199 TI - The reliability and validity of rating scales in assessing the clinical progress of psychiatric nursing students. PMID- 6912198 TI - Characteristics of geriatric patients as related to nursing needs. PMID- 6912200 TI - The emphasis and effect of hospital accreditation on nursing services. PMID- 6912201 TI - Role, selection and preparation of unit head nurses--II. PMID- 6912202 TI - Successful control of hepatitis B surface antigenemia in a dialysis unit without geographic or machine isolation. AB - Persistent hepatitis B infections among patients and frequent new hepatitis B infections among both patients and staff were a major problem in our dialysis unit during its first two and one-half years of operation. During this time the mean quarterly rate of conversion to HBsAg positivity among patients ranged from 0-60% (mean 12%); in staff it ranged from 0-13%. Control efforts, including strict temporal isolation, improved sanitary measures, and use of parallel plate dialyzers without geographic or machine isolation, were begun late in 1976. After a four-month lag, new HBsAg conversions ceased among the 30 patients and staff at risk, despite continued dialysis of eight HBsAg-positive patients (at least four of whom were HBeAg-positive). Over the succeeding three years the conversion rate was zero in both patients and staff. This experience suggests that conservative control measures without geographic separation of patients may be sufficient to control an established outbreak of hemodialysis-related hepatitis B. Controlled prospective trials of this hypothesis are warranted. PMID- 6912203 TI - Prophylactic antibiotics in pediatric orthopedic surgery: current practices. AB - A limited survey of 90 orthopedic surgery programs throughout the U.S.A. was conducted to determine the use of prophylactic antibiotics in pediatric orthopedic operations. Prophylaxis was used most often in the Harrington rod procedure (80.7%); less often in hip (64.2%) and knee (44.7%) reconstructive surgery; rarely in meniscus repairs (8.0%) and in lengthening of Achilles tendons (2.3%). Cephalosporins (85%) were the antibiotics prescribed most frequently. The first dose was administered before surgery in 89.6% of the operations. Prophylaxis was discontinued within five days in 96% of the operations. These data provide a pattern of the use of prophylaxis in pediatric orthopedic surgery. PMID- 6912204 TI - Epidemiologic studies of an outbreak of nosocomial methicillin-resistant Staphylococcus aureus infections. AB - In a six-month period in 1978 61 patients at a university hospital became colonized or infected with methicillin-resistant Staphylococcus aureus (MRSA). Ninety-three percent of patients with MRSA were on surgical services. Patients with burns acquired MRSA more frequently than did other acutely ill surgical patients (p less than .001), and often remained colonized for 30 days or more. The interval between admission and acquisition of S. aureus, number of antibiotics received, duration of antibiotic therapy before becoming colonized, and cost of hospitalization, were significantly greater in patients with MRSA infection than in matched controls with nosocomial methicillin-sensitive S. aureus infections. Acquisition of MRSA was epidemiologically associated with exposure to certain hospital personnel. Fourteen (6%) of 220 personnel exposed to MRSA patients harbored MRSA intranasally. Three of 14 colonized personnel carried MRSA intermittently for three or more months. Appropriate control measures failed to terminate the outbreak. PMID- 6912205 TI - Hospital infections: the state of the art in Italy. PMID- 6912206 TI - Reye's syndrome. PMID- 6912207 TI - The law and infection control. The myth of negligence. PMID- 6912208 TI - Topics in clinical microbiology: tracheostomy and endotracheal tube specimens. PMID- 6912209 TI - Applied statistics in infection control: some comments on multiple regression and analysis of covariance. PMID- 6912210 TI - Guideline for prevention of catheter-associated urinary tract infections. PMID- 6912211 TI - Cornerstones of an effective infection control program. PMID- 6912212 TI - Nosocomial bacteremia in perspective: a community-wide study. AB - Prospective surveillance of 1,527 episodes of bacteremia in the four major hospitals serving a community of 300,000 revealed striking differences among the hospitals. The rate of community-acquired bacteremia ranged from 1.9 to 6.8 per 1000 discharges; the rate of nosocomial bacteremia ranged from 0.9 to 9.8 per 1000 discharges. Death rates attributed to nosocomial bacteremias varied among the hospitals by as much as 40-fold. Nosocomial bacteremias were less frequent at two community non-teaching hospitals than at two teaching hospitals. Although fewer blood cultures were obtained at the nonteaching hospitals, the ratio of blood cultures obtained to deaths attributed to bacteremic infection was highest at these hospitals, suggesting that physicians recognized the importance of obtaining blood cultures in critically ill patients. The potential usefulness of bacteremia surveillance is reviewed. It is suggested that hospitals serving a single community might constitute an appropriate unit for such surveillance. PMID- 6912213 TI - Sinus contamination with Pseudomonas paucimobilis: a pseudoepidemic due to contaminated irrigation fluid. AB - During a five-week period, Pseudomonas paucimobilis was isolated from maxillary sinus irrigation washes of four patients who attended an ear, nose and throat clinic. The saline irrigation solution was found to be contaminated with the same organism. Further investigation demonstrated the organism in a majority of hospital sinks surveyed. Although P. paucimobilis was isolated from clinical specimens, the presence of the organism did not appear to have clinical significance. PMID- 6912214 TI - Nosocomial viral infections: IV. Guidelines for cohort isolation, the communicable disease survey, collection, and transport of specimens for virus isolation, and considerations for the future. AB - Virus transmission within the hospital is related to transmissibility of the virus and susceptibility of the population at risk. General guidelines for the use of cohort isolation, for the control of virus transmission in the hospital, and for the use of the communicable disease survey for pediatric patients and visitors to the hospital are out-lined. We also present a brief review of how to collect and transport specimens for virus isolation to assist the infection control practitioner and the clinician and conclude with recommendations for further investigations in the areas of virology and infection control. PMID- 6912215 TI - Statistical test for possible infection outbreaks. PMID- 6912216 TI - Immunizations: risks and warnings about them. PMID- 6912217 TI - Infection control in perspective: infections due to medical equipment and devices. PMID- 6912218 TI - Ordering patterns, collection, transport, and screening of sputum cultures in a community hospital: evaluation of methods to improve results. AB - The clinical usefulness of sputum cultures depends on the quality of specimens submitted to the laboratory. In a community hospital, during two separate surveillance periods, we evaluated ordering practices and circumstances under which sputum specimens were obtained and techniques to improve the quality of the specimens. Physicians themselves rarely participated in obtaining specimens of sputum, and members of the nursing staff directly instructed patients or supervised specimen collection in only one third of cases. The mean elapsed time from collection at the bedside to processing in the laboratory was two hours, with a range from several minutes to 13 hours. One fifth of all the specimens in this study were obtained from patients with no discernible evidence of lower respiratory tract infection. Microscopic screening revealed that one half of the specimens were of poor or uncertain quality. After the first survey, inservice education of nursing personnel in the proper techniques of sputum collection, along with regular use of the screening procedure in the clinical laboratory, failed to effect any long-term change in ordering patterns or collection practices. However, the screening procedure did improve the quality of the sputum cultured, through rejection of unsatisfactory specimens. PMID- 6912219 TI - Recurrent meningococcal meningitis caused by poly groups X-W135: importance of chemoprophylaxis. AB - Presented is a case report and literature review of the causes of recurrent meningococcal meningitis. After all factors were analyzed, the cause of reinfection in this child was postulated to be ineffective chemoprophylaxis of close contacts following the initial episode. The efficacy of chemoprophylaxis in household members and close contacts in meningococcal disease, although not demonstrated in controlled trials, has been recommended since 1974 by the Meningococcal Disease Surveillance Group. Considering known carriage rates, reports of secondary infections in close contacts, reinfection in the same person, and a high case fatality ratio, chemoprophylaxis in such cases seems justified. PMID- 6912220 TI - Toxocariasis in an institution for the mentally retarded. AB - A seroepidemiologic investigation was conducted in order to determine the cause of an apparent increase in rates of eosinophilia among 1400 institutionalized children during 1976-1977. The annual serologic survey during this period revealed 283 (20%) individuals with eosinophilia that exceeded 600 cells/cu mm of blood. During a five-month period in 1977, five patients who were hospitalized in adjacent wards developed acute pneumonia with eosinophilia. Because laboratory tests of sputum, bone marrow, and stool failed to identify the etiologic agent, it was thought that these pneumonia cases might be related to the increased rates of eosinophilia. Analyses of random samples of sera from patients with eosinophilia revealed seroprevalence rates of 12% for Ascaris, 20% for Toxocara canis, 24% for Strongyloides stercoralis, and 32% with increased antibody to Entamoeba histolytica. Further investigation showed a statistically significant positive association between occurrence of eosinophilia and pica behavior, and eosinophilia and contact with dogs. Although the serologic survey showed patients to have had previous exposure to a variety of parasites, we hypothesize that a principal cause of eosinophilia among institutionalized children may be Toxocara infestation, due to their frequent pica behavior and, in this case, contact with resident animals. We recommend that children in similar facilities have limited contact with pet dogs, and only after frequent and vigorous examination of the animals for infectious parasites. PMID- 6912221 TI - The law and infection control. Immunizations: part II. PMID- 6912222 TI - Topics in clinical microbiology: clinical considerations in the detection of bacteremia. PMID- 6912223 TI - Applied statistics in infection control: analysis of variance with group interactions. PMID- 6912225 TI - Introducing the nursing process in Papua New Guinea. PMID- 6912224 TI - Maltreatment of children - the tragedy of yesterday and today. PMID- 6912226 TI - The preparation of primary care nurse practitioners. PMID- 6912227 TI - A profession and its leadership. PMID- 6912228 TI - Overactivity in young children: how health visitors can help. PMID- 6912229 TI - The last taboo: child sexual abuse - its causes and effects. PMID- 6912230 TI - A practical approach to preventing child abuse. PMID- 6912231 TI - Child abuse and the role of the school nurse. PMID- 6912232 TI - Exercise and coronary risk factor modification in the management of atherosclerosis. PMID- 6912233 TI - Comparison of aortic and brachial cuff pressures in flat supine and lateral recumbent positions. AB - Systolic, diastolic, and mean aortic pressures and bilateral systolic and diastolic brachial pressures were measured in supine and right and left lateral recumbent positions. There were no significant differences between aortic pressures recorded in supine and lateral positions. Brachial pressures measured in lateral positions (up arm, down arm) were corrected for hydrostatic effects. Uncorrected up-arm pressures demonstrated a mean drop of 13 to 14 mm Hg in systolic pressure and 14 to 17 mm Hg in diastolic pressure below corresponding supine pressures. Corrected up-arm pressures were within 3 mm Hg of their respective supine pressures. Hydrostatic effects are the most likely cause of the drop in up-arm pressures. Down-arm pressure findings were inconsistent. Influences including hydrostatic effects and flow changes resulting from compression of the brachial artery by the weight of the person's body on the arm may account for this inconsistency. Brachial pressures, when possible, should be taken in supine or sitting positions. When pressures are taken with the patient in the lateral recumbent position, the up arm should be used. Up-arm pressures will be predictably lower than respective supine pressures, whereas down-arm pressures are inconsistent. PMID- 6912234 TI - A population-based study of factors associated with the prognosis of acute myocardial infarction. PMID- 6912235 TI - Cardiac monitoring in tricyclic antidepressant overdose. PMID- 6912236 TI - The Mega-Code for training the advanced cardiac life support team. PMID- 6912237 TI - A systems approach to nursing the patient with multiple systems failure. PMID- 6912238 TI - An examination of the physiologic basis for "coronary precautions". AB - The only restriction in the list of coronary precautions that is well supported by research is the restriction of stimulant beverages. The restriction of taking rectal temperatures and the rationale usually given, vagal stimulation, are not supported by clinical studies. The restriction of iced beverages has some support only if the amount of fluid is about 600 to 800 cc and if the patients is in the supine position, allowing the heart to be cooled. Limiting the ingestion of ice water to a glass of less at a time would seem to be supported by the studies reviewed and by a recent study of healthy young adults. In contrast to the conclusions drawn in this study, a recent national survey of nurses who care for cardiac patients revealed that coronary precautions remain in practice. Mean importance and frequency ratings for the individual restrictions were comparable to ratings for other commonly practiced nursing activities; however, the standard deviations for the mean ratings were greater for coronary precaution items than for others. Hopefully this article will summarize needed information, and nurses will be able to make decisions for practice on the basis of research rather than tradition. PMID- 6912239 TI - A tracheal tumor simulating asthma in a child. PMID- 6912240 TI - Alternating Wolff-Parkinson-White pattern. PMID- 6912241 TI - A study of aberrant ventricular conduction vs. ventricular ectopy. PMID- 6912242 TI - Cardiac auscultation in acute myocardial infarction. PMID- 6912243 TI - An unusual complication of acute myocardial infarction. PMID- 6912244 TI - Double-blind cross-over trial of an enzyme preparation in pancreatic steatorrhoea. PMID- 6912245 TI - The effects of a post-transcriptional modification on the function of tRNALys isoaccepting species in translation. AB - Isoacceptors of rabbit liver tRNALys which preferentially translate the codon AAG were compared for their function in several aspects of translation. As shown in other laboratories, Lys-tRNALys1,2 are two isoacceptors which differ from each other by a single base pair and are fully modified with N6-threonyl-adenosine adjacent to the anticodon. Lys-tRNALys4, which occurs commonly in rapidly dividing mammalian cells and tissues, is hypomodified at several bases and contains a precursor of N6-threonyl-adenosine next to its anticodon. These isoacceptors were incubated in cell-free protein synthesizing systems which contain rabbit globin mRNA. (Lys-tRNALys3 which translates AAA was also included.) The resulting globin was isolated and digested with trypsin, and the relative incorporation of lysine from Lys-tRNALys1,2 and from Lys-tRNALys4 into lysine-containing sites in the globin peptides as determined. Lys-tRNALys1,2 and Lys-tRNALys4 translate AAG preferentially, but Lys-tRNALys4 wobbles more than the former and translates AAA codons more efficiently. Overall, Lys-tRNALys1,2 is preferred in globin synthesis by about 30% compared to Lys-tRNALys4, and with one exception, the incorporation of lysine into the individual AAG lysine-containing sites in globin occurs more efficiently from Lys-tRNALys1,2. There is, however, considerable variation from site to site in the relative efficiencies of the Lys tRNAs in incorporation. PMID- 6912246 TI - Continuing education impact evaluation. PMID- 6912248 TI - New perspective in continuing education: travel education. PMID- 6912247 TI - Nurses in primary care: educational background and functioning. PMID- 6912249 TI - Methods of teaching - revisited the interview. PMID- 6912250 TI - Nurse response to continuing education: relevant factors in marketing success. PMID- 6912251 TI - Whose reality: ramifications for marketing in adult education. PMID- 6912252 TI - An educational program for the prevention and management of disturbed behavior in psychiatric settings. PMID- 6912253 TI - Precepting as an entry method for newly hired staff. PMID- 6912254 TI - Implementation of the preceptor concepts: adaptation to high stress climate. PMID- 6912256 TI - Notes on continuing education: research and continuing education. PMID- 6912255 TI - Methods of teaching--revisited case method. PMID- 6912257 TI - The bottom line. PMID- 6912258 TI - Needs assessment as a marketing strategy. PMID- 6912259 TI - Factors influencing the compliance of hemodialysis patients with their therapeutic regimen. PMID- 6912260 TI - Value of a self-help group in the psychosocial adjustment of end-stage renal disease clients and their families. PMID- 6912261 TI - Home hemodialysis and the spouse assistant. PMID- 6912262 TI - Self-care for children and adolescents on dialysis. PMID- 6912263 TI - Familial response to chronic illness: the impact of home versus hospital dialysis. PMID- 6912264 TI - Perceptions and misperceptions about nursing. PMID- 6912265 TI - Personal space boundary needs of elderly persons: an empirical study. PMID- 6912267 TI - Ethical issues in the selection of a theoretical framework for gerontological nursing research. PMID- 6912266 TI - Reducing the risks to the institutionalized elderly: Part I. Depersonalization, negative relocation effects, and medical care deficiencies. Part II. Fire, food poisoning, decubitus ulcer and drug abuse. PMID- 6912268 TI - A man and a woman in the middle years. PMID- 6912269 TI - Notes on a guide to gerontic practice. PMID- 6912270 TI - Nursing intervention in support of reminiscence. PMID- 6912271 TI - Pacing effects of medication instruction for the elderly. PMID- 6912272 TI - Helping caregivers cope with loss, especially dying. PMID- 6912273 TI - Assessing confusion: a tool to improve nursing care. PMID- 6912274 TI - Groups and student teaching; putting health education into practice. PMID- 6912275 TI - Measles, histocompatibility leukocyte antigen polymorphism, and natural selection in humans. AB - Profound lymphocytopenia (greater than 2,000 lymphocytes/mm3) occurring within two days of rash in 69 South African black children with measles predicted either death or progression to chronic lung disease in 51 (77%) of 66 children who were followed for at least six weeks. Lymphocytopenia was significantly associated with the presence of histocompatibility leukocyte antigen (HLA) AW32 (P = 0.01), with a relative risk of 5.5. There was a trend toward an association between the presence of particular antigens in the HLA complex and the various indices of humoral and cellular immunity studied. These findings are discussed in terms of variation in the clinical spectrum of the disease and in relation to the evolution of HLA polymorphism. PMID- 6912278 TI - Role of elongation factor 1 in the translational control of rodent brain protein synthesis. AB - The translational control of protein synthesis during early postnatal neural development and aging was examined in the mouse and the rat. The activity of brain elongation factor 1 (bEF-1) was found to decrease exponentially with age and to decline parallel to the age-dependent decrease in total protein synthesis in both rodents. This decrement in bEF-1 activity fell within the range of reported age-related decreases in protein synthesis in in vitro systems. The factor was present in multiple forms; the lighter species predominated in older animals, whereas the young light form apparently disappeared with increasing age, and was replaced by other arising from the heavy form. Elongation factor 1 derived from young brains functioned as a rate-limiting component in polypeptide synthesis in previously saturated adult systems. The data suggest that bEF-1 has an important modulatory effect on total brain protein synthesis. PMID- 6912276 TI - Human monocyte spreading induced by factor Bb of the alternative pathway of complement activation. A possible role for C5 in monocyte spreading. AB - The central serine esterase of the alternative pathway of complement (APC) activation, activated factor B (Bb), has been shown recently to induce murine macrophages and human monocytes to become spread on a glass substrata. It has also been established that to induce the spreading reaction, the catalytic site of the Bb enzyme must be structurally intact since treatment of Bb with heat (56 degrees C for 30 min) or diisopropylfluorophosphate (10(-3) M) destroyed both enzymatic and spreading activities. In the C3b,Bb complex, Bb exhibits restricted substrate specificity for C3 and C5. With this in mind, the role of C3 and C5 in the monocyte spreading reaction was explored in the present study. Expression of C3 and C5 on the surface of human peripheral blood monocytes was investigated by the direct fluorescent antibody technique employing fluorescein isothiocyanate conjugated anti-C3 or C5 F(ab')2 antibody fragments. It was found that C3 and C5 were present on 6 +/- 7% of freshly prepared monocytes and that expression of C5, but not C3, increased to 70 +/- 6% when monocytes were incubated for 3 d in serum free medium. Biosynthesis of C5 was indicated when it was found that under serum free conditions, monocytes incorporated [3H]leucine into immunoprecipitable C5 with an apparent mol wt of 180,000 on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The role of C3 and C5 in the monocyte spreading reaction induced by factor Bb was explored by testing for the ability of anti-C3 and anti-C5 Fab' antibody fragments to block monocyte spreading. It was found that anti-C5 Fab' inhibited by up to 100% the 3-h human monocyte spreading reaction induced by Bb; in contrast, anti-C3 Fab' or anti-C4 Fab' inhibited by less than 10%. That the inhibitory effect of anti-C5 Fab' was exerted directly on the monocyte was established when it was found that the 3-h monocyte spreading reaction was significantly inhibited by pretreating monocytes with anti-C5 Fab' for 20 min and then washing before the addition of Bb. The specificity of the inhibitory effect of anti-C5 Fab' was established by quantitatively absorbing the antibody fragments with polyacrylamide gel-purified C5 antigen: greater than 4 microgram of C5 absorbed by 100% the inhibitory activity of 10-20 microgram of anti-C5 Fab'. That factor Bb exerted its effect on monocytes by interacting directly with cell surface C5 was indicated when it was found that purified C5 inhibited the monocyte spreading reaction induced by Bb; greater than 25 microgram of C5 inhibited by 100% the spreading reaction induced by 3 microgram factor Bb. PMID- 6912277 TI - Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3. AB - Activation of the alternative pathway of complement commences with the formation of an initial fluid-phase C3 convertase. Treatment of C3 with the nucleophilic reagent methylamine has previously been shown to result in the cleavage of an intramolecular thioester bond and to induce C3b-like properties, including the ability to form a fluid-phase C3 convertase. This report examines the hypothesis that spontaneous hydrolysis of the thioester generates a derivative of C3 that is responsible for the formation of the initial C3 convertase of the alternative pathway. The rate of spontaneous decay of C3 hemolytic activity in buffer was found to be between 0.2 and 0.4%/h. In the presence of other alternative pathway proteins, the rate of inactivation was 1%/h. The rate of spontaneous inactivation was greatly accelerated by low concentrations of chaotrophic agents such as KSCN or guanidine. Liberation of a sulfhydryl group, not present in native C3, correlated with loss of hemolytic activity, indicating that exposure to chaotropic agents resulted in thioester hydrolysis. Unlike native C3, C3 bearing a single reactive sulfhydryl group was capable of generating fluid-phase C3 convertase with Factors B, D, and P and was cleaved by Factor I (C3b inactivator) in the presence of Factor H (beta 1H). The fragmentation patterns indicated that the C3a domain was covalently associated with the functionally C3b-like C3. Organomercurial agarose was employed for the rapid removal of sulfhydryl-bearing, hemolytically inactive forms of C3 and C3b from native hemolytically active C3. PMID- 6912279 TI - Transsphenoidal hypophysectomy for pituitary tumors. PMID- 6912281 TI - Carpal tunnel syndrome. PMID- 6912280 TI - Brain abscess. PMID- 6912282 TI - A prospective study of patients with central nervous system trauma. PMID- 6912283 TI - Identification, implementation, and utilization of a research clinical specialist in a neuroscience setting. PMID- 6912284 TI - [Nursing care of the patient cardiac catheterization]. PMID- 6912285 TI - [A study of the results of teaching the patient before open heart surgery, and comparing the different results with different ages]. PMID- 6912286 TI - [Nursing care of a 6-year-old boy in ICU after open heart surgery]. PMID- 6912287 TI - [Swan Ganz: Swan Ganz catheter and its nursing care]. PMID- 6912288 TI - [The application of chest physiotherapy in pediatric nursing care]. PMID- 6912289 TI - [Care of the patient with coronary heart diseases]. PMID- 6912290 TI - [Study of rewarming for 24 hour-neonates in nursery]. PMID- 6912291 TI - [Continuous ambulatory peritoneal dialysis]. PMID- 6912293 TI - [Introduction of heart surgery]. PMID- 6912292 TI - [Virus B hepatitis]. PMID- 6912295 TI - [Change theory and its application in nursing]. PMID- 6912294 TI - [Stress in the nurse]. PMID- 6912296 TI - Breakthrough: nursing consultation records. PMID- 6912297 TI - Outside staffing sources--the suppliers' view. PMID- 6912298 TI - Managerial control versus professional autonomy: a paradox. PMID- 6912300 TI - Patient education in hospitals: developmental issues. PMID- 6912299 TI - Peer review: a perspective for performance appraisal. PMID- 6912301 TI - Hospital decision making: what is nursing's role? PMID- 6912302 TI - Nurse/physician collaboration: nursing practice considerations. PMID- 6912303 TI - The rebirth of the cervical cap. PMID- 6912305 TI - Faculty burn-out in nurse-midwifery education. PMID- 6912304 TI - Nurse-midwives in a hospital birth center. PMID- 6912306 TI - Two roads--which one? PMID- 6912307 TI - Pharmacology update: penicillins - Part III. PMID- 6912308 TI - Osteoarthritis: management requires sound patient teaching. PMID- 6912309 TI - Caring for the cleft palate child: nursing solutions for a family problem. PMID- 6912310 TI - The problem patient: a hotel or a hospital? Applying the principles of reality orientation. PMID- 6912311 TI - What's so special about my specialty? Critical care nursing. PMID- 6912312 TI - Legal aspects of nursing. PMID- 6912313 TI - Rape awareness. PMID- 6912314 TI - Pain and suffering. PMID- 6912316 TI - Pharmacology update: penicillins--Part IV. PMID- 6912315 TI - Are you just an LPN? PMID- 6912317 TI - The patient in the middle. Caring for your middle-aged patient. PMID- 6912318 TI - Back to basics: diverticular disease. PMID- 6912319 TI - Catheter care and UTI. The nurse's role in prevention and treatment. PMID- 6912320 TI - Don't stereotype your patients. PMID- 6912321 TI - Electrical characteristics of waveguide applicators for medical applications. AB - This work concerns the electrical properties of waveguide applicators consisting of flanged rectangular waveguides filled with a dielectric, used in medical applications (microwave thermography and local hyperthermia). The reflection coefficient and the near field configuration in lossy materials were obtained in some cases analytically and in some other cases numerically. The validity of these methods was verified experimentally. The study shows that the matching of the applicator and the penetration depth in a lossy material, such as a living tissue, depend not only on the tissue characteristics but also on the characteristics of the applicator itself. PMID- 6912322 TI - Nursing students and issues of client modesty/sexuality. PMID- 6912323 TI - Nurse legislators. PMID- 6912324 TI - Self Rx. PMID- 6912326 TI - Nursing education on the high plains at Fort Hays State University. PMID- 6912325 TI - Private nursing practice in Kansas. PMID- 6912327 TI - Nursing education on the high plains at Fort Hays State University. Program evaluation - why bother? PMID- 6912328 TI - A state of transition - nursing education in Hutchinson, Kansas. PMID- 6912329 TI - Concerns of fathers throughout the childbearing cycle: a review of the literature. PMID- 6912330 TI - Standards of mental health nursing practice. PMID- 6912331 TI - Is privacy important in scoliosis screening? PMID- 6912332 TI - The concept of health and the role of health education. AB - The field of health education needs to establish a conceptual basis that provides a legitimate focus and direction for health education. Health education should recognize that notions of health are human constructs which are restricted by man's interpretation of the functional integrity of the body and mind and relative to the activities and interests of individual societies. Health education should define health as that state of body and mind functioning which affords man the ability to strive towards his functional objectives and his culturally desired goals. The function of health education should be to impart knowledge for the purpose of developing the powers of reason and judgement in order to help people make their own choices about patterns of living which enhance the well functioning of the body and mind. PMID- 6912333 TI - Organization and function of a school health council. PMID- 6912334 TI - Selected publications for professional health educators. PMID- 6912335 TI - School nurse practitioners: analysis of questionnaire and time/motion data. PMID- 6912336 TI - Health education planning in health systems agencies. PMID- 6912337 TI - Public schools as a clinical experience for nursing students. PMID- 6912339 TI - PRECEDE for wellness. PMID- 6912338 TI - Reasons given by female virgins for not having premarital intercourse. AB - By analyzing reasons given by virgin women for not engaging in premarital coitus, we can attain greater insight into the decision-making process involved in maintaining virginity as well as in the transition to nonvirginity. Among virgin women, there is a subgroup who are likely to have premarital coitus if they should meet the right person. On the other hand, women who give moral reasons for not engaging in coitus are the least likely to engage in premarital coitus even if they should become involved in a love relationship. Our results suggest that counsellors and educators should be aware of the diversity of reasons for not engaging in premarital intercourse as well as factors influencing these reasons in order to gain a more complete understanding of premarital sexual decision making. PMID- 6912341 TI - [The current method of communication between nurses at the change of shift and possible improvement of this method--a study on the method of communication at a training hospital]. PMID- 6912340 TI - Alyce annie: a new CPR home practice manikin. PMID- 6912342 TI - [On key points in communication concerning the patients--the contents of the information to be communicated]. PMID- 6912343 TI - [Legal significance of communication by nurses on patients' conditions]. PMID- 6912345 TI - [Day care at the Musashino Clinic: a review of the last 6 1/2 years]. PMID- 6912344 TI - [Improvement of methods of communication by nurses on patients' conditions. A discussion]. PMID- 6912346 TI - [Human science. Religion (2). Personality relationship and religion]. PMID- 6912347 TI - [Bedside conference: planning of clinical training (5). The digestive system (1)]. PMID- 6912348 TI - [Nurses in an organization: motivation and morale (2). (5) Motivation and morale of health personnel]. PMID- 6912349 TI - [Nursing education and technological education (1)]. PMID- 6912350 TI - [Medical labels and nursing education]. PMID- 6912351 TI - A framework for ethical action in nursing service administration. PMID- 6912352 TI - [Diagnosis and treatment of the most wide-spread general proctological diseases]. PMID- 6912353 TI - [Chronic colitis]. PMID- 6912354 TI - [Acupuncture reflexotherapy of chronic nonulcerative colitis]. PMID- 6912355 TI - [Diet in chronic colitis]. PMID- 6912356 TI - [Familial diffuse polyposis of the large intestine]. PMID- 6912357 TI - [Cancer of the colon]. PMID- 6912358 TI - [Cancer of the rectum]. PMID- 6912360 TI - [Endoscopic studies in diseases of the large intestine]. PMID- 6912359 TI - [Health of the people is our wealth]. PMID- 6912361 TI - [X-ray study characteristics of the large intestine]. PMID- 6912362 TI - [Treatment of proctological patients by physical methods]. PMID- 6912363 TI - [Work of the physical therapy nurse in the proctology ward]. PMID- 6912364 TI - [What the nurse should know about blood transfusion]. PMID- 6912365 TI - [Use for therapeutic purposes of electrosleep and musical melodies]. PMID- 6912366 TI - [Air cushion for patients with eye pathology]. PMID- 6912367 TI - [Role of the patients' council in a psychiatric ward]. PMID- 6912368 TI - [Ginseng and its relatives]. PMID- 6912369 TI - [Military and patriotic student education]. PMID- 6912370 TI - [Tutorship]. PMID- 6912371 TI - [Problems of medical ethics and deontology in Soviet public health legislation]. PMID- 6912372 TI - [Organization of medical service for proctology patients]. PMID- 6912374 TI - You can refuse dangerous work if. PMID- 6912373 TI - Position paper on change of governance at W.C.G.H. Wayne County Professional Nurse Council. PMID- 6912375 TI - Independence or the transfer of control. PMID- 6912377 TI - You are a witness! In arbitration. PMID- 6912378 TI - You are a witness! Grievance and arbitration. PMID- 6912376 TI - We did it at U-M. PMID- 6912379 TI - Effect of present patterns of maternity care on the emotional needs of mothers: Part 3. PMID- 6912380 TI - The passing of the Midwives' Act, 1902. PMID- 6912381 TI - "Midwifery-past and present;;. PMID- 6912382 TI - [Mechanism of codon-anticodon interaction in ribosomes. Interaction of aminoacyl tRNA with 70S ribosomes in the absence of elongation factor EF-Tu and GTP]. AB - Purified Phe-tRNAPhe revealed higher affinity to the donor (D) site of vacant 70S . poly(U) complex than to the acceptor (A) site, independent on Mg2+ concentration. As a result, in excess of ribosomes Phe-tRNAPhe binds exclusively to the D site. This was proved using the tests in the presence of tetracycline and puromycin. Preferential binding of Phe-tRNAPhe to the D site was used to measure equilibrium association constants of this interaction at different temperatures and Mg2+ concentrations. A large value of reaction enthalpy (ca. -26 Kcal/mole) was found. PMID- 6912383 TI - [Role of the anticodon loop in triggering conformational changes of tryptophanyl tRNA synthetase by tRNA Trp]. AB - The circular dichroic spectrum of the bovine tRNATrp is altered in complex with homologous tryptophanyl-tRNA synthetase showing the conformational changes of the substrate under the action of enzyme. The conversion of the exposed cytosine into uridine bases in tRNATrp (beef, yeast) does not prevent complex formation but abolishes the tRNA action on the limited proteolysis of the synthetase. It was shown that elimination of this type of tRNA activity is solely attributed to the cytosine leads to uridine conversion in the anticodon loop. A conclusion is made that the anticodon loop of the tRNATrp plays a dominant role in triggering conformational changes of the synthetase under substrate action whereas the CCA end is not directly involved in this process. PMID- 6912384 TI - Inhibitory effect of elastase on the glomerular capillary basement membrane thickening of the experimental congenital diabetic mice (N.S.Y. mice). PMID- 6912386 TI - Experimental evidence and social policy. PMID- 6912387 TI - Experimentation in human populations. PMID- 6912385 TI - Liberation of catecholamines and 5-hydroxytryptamine from human blood-platelets. AB - Spontaneous and drug-induced liberation of 14C-5-hydroxytryptamine (14C-5HT), 3H dopamine (3H-DA) and 3H-noradrenaline (3H-NA) from normal and reserpinized human blood-platelets has been determined from measurements of the amine contents before and after incubation in tris-buffer. In normal platelets the spontaneous liberation of 3H-catecholamines was more marked than that of 14C-5HT, but was less in percent for all these labelled amines than in reserpinized platelets. Thrombin lowered amine contents more in normal than in reserpinized platelets. The initial thrombin-induced decrease of 14C-5HT, in contrast to that of 3H catecholamines, showed a partial recovery after 30 min which was abolished by imipramine. The benzoquinolizine Ro 4-1284 diminished all the amines in normal, but not in reserpinized platelets. In normal platelets tryamine affected 14C-5HT and 3H-DA about equally, whereas 3H-NA much less. Octopamine showed a similar pattern as tryamine, but was less potent. P-chlormethamphetamine (PCMA) and amphetamine decreased 3H-DA less markedly than 14C-5HT and 3H-NA not at all. In reserpinized platelets these arylalkylamines induced a decrease of 14C-5HT but not of 3H-catecholamines. It is concluded that (a) 3H-catecholamines like 14C-5HT are mainly localized in the granular pool of normal human platelets, (b) the pattern of action of a drug on intra- and extragranular amines depends not only on the nature of the drug and the amine to be liberated, but in comparison with previous results also on the species, (c) platelets are not completely satisfactory models for monoaminergic neurons, especially catecholaminergic ones regarding drug-induced amine liberation. PMID- 6912388 TI - Social experiments. PMID- 6912390 TI - Preparing a staff nurse for precepting. PMID- 6912389 TI - From "promising report" to "standard procedure": seven stages in the career of a medical innovation. PMID- 6912393 TI - Teaching problems and strategies with male nursing students. PMID- 6912391 TI - Moving toward interdependence: strategies for collaboration. PMID- 6912392 TI - Continuing education/continuing practice. PMID- 6912394 TI - Sharing: holy Joe. PMID- 6912396 TI - Screening for skin cancer: a necessary part of your assessment routine. PMID- 6912395 TI - Rescind the risks in administering anticoagulants. PMID- 6912397 TI - To defeat hypovolemic shock, anticipate and act swiftly. PMID- 6912398 TI - Giving an autotransfusion with MAST. PMID- 6912400 TI - Day in and day out you minister to others--but who will minister to you? PMID- 6912401 TI - It took ten of us--from various disciplines--to care for one troubled patient. PMID- 6912399 TI - When all else failed, Pavulon therapy worked. Nursing grand rounds. PMID- 6912402 TI - Timely techniques in caring for the patient with an endotracheal tube. Part 2. PMID- 6912403 TI - How autonomous are you? Nursing autonomy/patients' rights questionnaire. PMID- 6912404 TI - Your patient's anxious--what should you do? PMID- 6912405 TI - What to do when your patient's pacemaker stops working. PMID- 6912406 TI - Medication errors: if a drug doesn't look right, check with the pharmacist. PMID- 6912407 TI - Test your knowledge of the acute care patient. PMID- 6912409 TI - Nursing and the changing scene. PMID- 6912410 TI - Associate and assistant deanships in schools of nursing. PMID- 6912408 TI - A case against inflexible routine shift rotation. PMID- 6912411 TI - A black perspective: Afro-American men in nursing. PMID- 6912412 TI - Program evaluation in nursing utilizing Key Factor Analysis. PMID- 6912414 TI - A challenging role. PMID- 6912413 TI - The extension of the nurse's role--which way? PMID- 6912415 TI - Workshop: II. Change is possible. PMID- 6912416 TI - Voice of the ward sister IV. Interview by Celia Fairbrother. PMID- 6912418 TI - Liability of employing authorities for accidents at work. PMID- 6912417 TI - Relaxation while horse riding. Interview by Janet Barber. PMID- 6912419 TI - Regional close-up: South East Thames. PMID- 6912420 TI - Perspectives in nursing: this nurse is a patient advocate. PMID- 6912421 TI - Person-centered caring. PMID- 6912422 TI - Changing TGIF to TGIM. PMID- 6912423 TI - Nursing care plans. PMID- 6912424 TI - Uniting the management team. PMID- 6912425 TI - Pulling staff: problem or solution? PMID- 6912426 TI - Student learning: team vs primary nursing. PMID- 6912427 TI - You've changed...so we've changed. PMID- 6912428 TI - Evaluating ancillary staff of a health center. PMID- 6912429 TI - Monitoring supplemental staffing agencies. PMID- 6912430 TI - Art & science of management: nursing judgment. PMID- 6912431 TI - Law for the nurse manager: forced medication of mental patients. PMID- 6912433 TI - Who determines your nursing practice? - The certification question. PMID- 6912434 TI - Health education series - article IV. Selecting a nursing home. PMID- 6912432 TI - Focus: on the California State Board of Registered Nursing. PMID- 6912435 TI - Children's drawings as indicators of sexual trauma. PMID- 6912436 TI - Incest: an overview. PMID- 6912437 TI - Holism or hypocrisy? PMID- 6912439 TI - Family treatment for the disturbed child? PMID- 6912440 TI - NLN program goals for 1981-1983. PMID- 6912438 TI - Art media: a means to therapeutic communication with families. PMID- 6912441 TI - Tumor mitochondrial transfer ribonucleic acids: the nucleotide sequence of Morris hepatoma 5123D mitochondrial tRNA GUC Asp. AB - A mitochondrial aspartate tRNA (anticodon GUC) was isolated from a transplantable rat tumor, Morris hepatoma 5123D, and sequenced. The sequence, pGAGAUAUUm(1)AGUAAAAUAAUUACA psi AACCUUGUCAAGGUUAAGUUAUAGACUUAAAUCUAUAUAUCUUACCAOH, can be arranged in a cloverleaf structure. The RNA exhibits a number of unusual features, such as lack of the constant -G-G- and -T-psi-C- sequences in loops I and IV, respectively, small size of these loops, lack of the constant G.C base pair adjacent to loop IV, predominance of A.U base pairs in general, and presence of m1A in position 9. The RNA exhibits 82 and 70% homology with the DNA-derived putative sequences of human placenta and beef heart mitochondrial tRNA Asp, respectively, and bears little resemblance to other sequenced aspartate tRNAs of non-mitochondrial origin. PMID- 6912443 TI - Licensure: public protection or property right? PMID- 6912442 TI - The reaction of adenine and cytosine residues in tRNA with chloroacetaldehyde. AB - The reaction of Lupinus luteus tRNAPhe with 1 M chloroacetaldehyde in the pH range of 4 - 6 at 25 degrees C was studied. It was found that earlier difficulties lowering the utility of the reagent for structural studies of nucleic acids were caused by the formation of the stable reaction intermediates. In order to eliminate these difficulties the simple procedure of so-called maturation of the chloroacetaldehyde-modifies tRNA is proposed. It consists in further incubation of the short-term modified tRNA in water at 50 degrees C in the absence of the reagent. During the maturation step the stable intermediates are quantitatively converted into final ethenoderivatives. New HPLC conditions on Aminex A-6 were worked out which enable rapid separation of both ethenoadenosine and ethenocytidine from natural tRNA nucleosides. PMID- 6912444 TI - Anger: an occupational hazard for nurses. PMID- 6912445 TI - Nurses as co-providers of primary health care. PMID- 6912446 TI - Establishing a group private practice in nursing. PMID- 6912447 TI - Reflections while reading. PMID- 6912448 TI - Districting: an alternative community health experience. PMID- 6912449 TI - The refereed journal: prestige in professional publication. PMID- 6912450 TI - Accommodating RN students in baccalaureate nursing programs. PMID- 6912451 TI - The use of testing to modify curricula for RNs. PMID- 6912453 TI - Health and nursing: evolving one concept by involving the other. PMID- 6912452 TI - Whatever happened to caring? PMID- 6912454 TI - Family health as a perspective in assisting a family to cope with hospitalization. PMID- 6912455 TI - Nursing clients toward health: an analysis of nursing interventions. PMID- 6912456 TI - The role of a health sciences librarian in nursing education in Canada. PMID- 6912457 TI - Introduction to basic curriculum work. PMID- 6912458 TI - Nursing explorations: an introduction. PMID- 6912459 TI - Learning to nurse families: monitoring content and process. PMID- 6912460 TI - Learning to nurse families. PMID- 6912461 TI - Implementing program philosophy through curricular decisions. PMID- 6912462 TI - The health workshop: design to evaluate a prototype in primary nursing care. PMID- 6912463 TI - Mr. Priest's new parish. Interview by Laurence Dopson. PMID- 6912464 TI - A recipe for disaster. PMID- 6912465 TI - Back to school. PMID- 6912466 TI - Top marks for Tooting Bec. PMID- 6912467 TI - Warts and their treatment. PMID- 6912468 TI - Monitoring pressure sores. PMID- 6912469 TI - Helen House: our first hospice for children. PMID- 6912470 TI - Life before death. PMID- 6912471 TI - Report on the development and use of the first functional hip spica. PMID- 6912472 TI - Reality orientation--a way forward. PMID- 6912473 TI - A guide to writing nursing care studies. PMID- 6912474 TI - Discrepancies in the perceptions of a structural relationship for teamwork. 1. PMID- 6912475 TI - Educational developments: education and politics. PMID- 6912476 TI - Educational developments. 1. To teach or not to teach. PMID- 6912477 TI - Educational developments. 2. Continuous assessment: the pros and cons. PMID- 6912478 TI - Educational developments. 3. School nursing in the 80s. PMID- 6912479 TI - Trial and error. PMID- 6912480 TI - What about sister? PMID- 6912482 TI - A world of difference. PMID- 6912481 TI - Hands across the water. PMID- 6912483 TI - Nursing care study: right hemicolectomy for Crohn's disease. PMID- 6912484 TI - No man is an island. PMID- 6912485 TI - What every woman should know. PMID- 6912486 TI - Care and support for relatives in the ITU. PMID- 6912487 TI - The team of experts. PMID- 6912488 TI - English as she is doctored. PMID- 6912490 TI - Doctors not deities. PMID- 6912489 TI - Systems of life No 81. Systems and signs: reproductive system - 2. Female 1. PMID- 6912491 TI - Nurses and heroism. PMID- 6912492 TI - Towards better nursing care. PMID- 6912493 TI - RSCN's: where they go and why. 1. The postcard mailing. 2. Sick children's nursing in Brighton. PMID- 6912494 TI - Nursing care study: a patient suffering from Goodpasture's syndrome. PMID- 6912495 TI - The menopause - a wider view. PMID- 6912496 TI - The criteria for brain death in England - 2. PMID- 6912497 TI - Learning about method of research with the Open University. PMID- 6912498 TI - The good old days. PMID- 6912499 TI - Towards a healthy future. PMID- 6912500 TI - A new beginning. Interview by Laurence Dopson. PMID- 6912501 TI - Minds over matters. PMID- 6912502 TI - Rabies: the British point of view. PMID- 6912503 TI - The nurse manager and primary health care teams. PMID- 6912504 TI - The lead sandwich syndrome. PMID- 6912505 TI - Malignant strictures of the hepatobiliary system. PMID- 6912506 TI - Statistical returns in community psychiatric nursing-1. PMID- 6912508 TI - The NO jungle. PMID- 6912507 TI - Communication skills: "Cool it, man!' (feelings in talking). PMID- 6912509 TI - Health--a woman's right. PMID- 6912510 TI - Nursing care study: agitated depression. PMID- 6912512 TI - Day care cataract surgery. PMID- 6912511 TI - Airborne intensive care. PMID- 6912513 TI - The nursing contribution to social skills training for psychiatric in-patients. PMID- 6912514 TI - Continuous ambulatory peritoneal dialysis. PMID- 6912515 TI - A geriatric team within the health visiting service. PMID- 6912516 TI - A tale of two hospitals. PMID- 6912517 TI - Endoscopy disinfection workshop. PMID- 6912518 TI - The important part research plays in infection control. PMID- 6912519 TI - The Brendan Moore Educational Trust. PMID- 6912520 TI - Educational update: infection control nurses. PMID- 6912521 TI - Guidelines on the role of the infection control nurse. PMID- 6912522 TI - Why Polish midwives back Solidarity. PMID- 6912523 TI - Midwifery: episiotomy. PMID- 6912524 TI - Labour and delivery in North America. PMID- 6912525 TI - A study on aetiological factors of tuberculosis. PMID- 6912526 TI - Staffing an intensive care unit: the nursing component. PMID- 6912527 TI - Occupational health service for student nurses. PMID- 6912528 TI - Global strategy for health for all by 2000 A.D. PMID- 6912529 TI - National awards for nurses: a note on the relevant procedures and criteria. PMID- 6912530 TI - What prevents unity. PMID- 6912531 TI - Clinical forum 9. Obstetrics II: pre-eclampsia and eclampsia. PMID- 6912532 TI - Clinical forum 9. Obstetrics II: shock in obstetrics. PMID- 6912533 TI - Clinical forum 9. Obstetrics II: breech presentation. PMID- 6912534 TI - Clinical forum 9. Obstetrics II: Complications associated wih shock in obstetrics. PMID- 6912535 TI - Clinical forum 9. Obstetrics II: anaemia in pregnancy. PMID- 6912536 TI - Clinical forum 9. Obstetrics II: postpartum family planning. PMID- 6912537 TI - Student's view: the person behind the uniform. PMID- 6912538 TI - Off the record: some thoughts on ward visiting. PMID- 6912539 TI - Agnes Andrews: the president who keeps smiling. PMID- 6912540 TI - Nuclear medicine and nursing 3: on the beating track. PMID- 6912541 TI - Compassionate friends: when time doesn't heal all... PMID- 6912542 TI - Elsie Stephenson Memorial Lecture II: the shape of things to come. PMID- 6912543 TI - Drug dependency: a family matter. PMID- 6912544 TI - Diabetic retinopathy research: from a volunteer's view... PMID- 6912545 TI - Psychiatric nursing: wanted: a change of attitude. PMID- 6912546 TI - Appetite depressants: weights and measures. PMID- 6912547 TI - The nursing officer and primary health care team: making the team work. PMID- 6912548 TI - Myasthenia gravis: life transforming treatments. PMID- 6912549 TI - What the TUC wants. PMID- 6912550 TI - Encounters of the violent kind. PMID- 6912551 TI - In praise of dragons. PMID- 6912552 TI - Statistics never lie - or do they? PMID- 6912553 TI - Contraception for the under 16s: better safe than sorry. PMID- 6912554 TI - Operation count down. PMID- 6912555 TI - Nuclear medicine and nursing. 4. From diagnosis to cure. PMID- 6912556 TI - Students' forum - let's look at a problem: senile dementia. PMID- 6912557 TI - Staff/patient relations: a touching moment. PMID- 6912558 TI - Veterinary diseases and man: hydatid disease. PMID- 6912559 TI - The role of the nursing officer: who are they? PMID- 6912561 TI - Anxiety and the control of pain: highly illogical! PMID- 6912560 TI - Alternative midwifery: life on the farm. PMID- 6912562 TI - Perinatal mortality: it's the same old story. PMID- 6912563 TI - Help for the terminally ill: at your service. PMID- 6912564 TI - Nursing care study - chickenpox: causing complications. PMID- 6912565 TI - Nursing care study - deformity of toes: foot fault corrected. PMID- 6912566 TI - Reaching NO conclusions. PMID- 6912567 TI - Thoughts of a superstar. PMID- 6912568 TI - This one is not for killing. PMID- 6912569 TI - Touch and the elderly: more than a helping hand. PMID- 6912570 TI - Geriatric rehabilitation: a change of plans. PMID- 6912571 TI - Geriatric assessment: open to suggestions. PMID- 6912572 TI - Community nursing--geriatrics: risk comes before a fall. PMID- 6912573 TI - Community nursing--geriatrics: a measure of support. PMID- 6912574 TI - Nursing care study--femur fracture in an elderly patient: make or break. PMID- 6912575 TI - 'I wish my Ethel were here...'. PMID- 6912577 TI - Research: knowledge is a precious possession. PMID- 6912576 TI - Nurses and feminism: women together are strong. PMID- 6912578 TI - Participation of prostaglandins in the action of kinins on the central dopaminergic system in the rat. I. The action of kinins on the central dopaminergic system after pretreatment with indomethacin. AB - The effect of intraventricularly (ivc) administered bradykinin (BRS) and activation of kininogenic enzymes of the cerebral tissue by kallikrein on dopaminergic system was investigated in tests of amphetamine (AMPH) and apomorphine (APO)-induced stereotypy and haloperidol (HAL)-induced catalepsy in rats receiving an inhibitor of prostaglandin synthetase, indomethacin (IND). The cerebral content of dopamine (DA), noradrenaline (NA) and homovanillic acid (HVA) was determined after some dosage schedules. In rats pretreated with IND the action of AMPH was potentiated and modulated by kinins (depending on the dose). IND prolonged the duration of APO-induced stereotypy and antagonized the action of low dose (1 mu g) of BRS, but potentiated the action of high doses (2 and 4 mu g) of BRS. IND potentiated the action of BRS on catalepsy induced by a low dose of HAL (0.75 mg/kg) but abolished the action of BRS on the catalepsy produced by a high dose of HAL (1.25 mg/kg). The results of biochemical investigation do not explain in full the behavioral changes. PMID- 6912579 TI - The participation of prostaglandins in the action of kinins on the central dopaminergic system in the rat. II. Participation of PGF2 alpha in the action of kinins on the central dopaminergic system. AB - Administration of prostaglandin F2 alpha (PGF2 alpha) in the presence of kinins did not change or potentiated the action of amphetamine (AMPH). Depending on the dose, PGF2 alpha could antagonize or potentiate the effect of kinins on the apomorphine (APO)-induced stereotypy. A combined treatment with PGF2 alpha and kinins did not affect or potentiate the haloperidol (HAL)-induced catalepsy. Bradykinin (BRS) and PGF2 alpha given separately or in combination did not change the levels of dopamine (DA), homovanillic acid (HVA) and noradrenaline (NA) after administration of AMPH, but given in combination elevated the striatal level of DA after treatment with APO. PGF2 alpha given in combination with BRS to rats receiving alpha-methyl-p-tyrosine (alpha-MT) increased the DA turnover in the striatum, while combined treatment with PGF2 alpha BRS, APO and alpha-MT depressed the turnover rate. PMID- 6912580 TI - The participation of prostaglandins in the action of kinins on the central dopaminergic system in the rat. III. Participation of PGE1 in the action of kinins on the central dopaminergic system. AB - Prostaglandin E1 (PGE1) slightly inhibited the amphetamine (AMPH) induced stereotypy after administration of bradykinin (BRS) or stimulation the activity of kininogenic enzymes of the cerebral tissue by kallikrein administration. After administration of PGE1, BRS did not affect the apomorphine (APO)-induced stereotypy. The effect of kinins on catalepsy induced by haloperidol (HAL) was changed depending on the dose of PGE1. PGE1 given in combination with BRS increased the NA turnover in the rat striatum in comparison with the group receiving BRS, and given together with BRS and APO depressed the NA turnover in comparison with the group BRS and APO. A combined administration of PGE1 and BRS did not change the DA and HVA content under the experimental conditions used. PMID- 6912581 TI - How to avoid summer food poisoning! PMID- 6912582 TI - Nurse and aide: a nursing assistant's point of view. PMID- 6912583 TI - The impact of nursing. PMID- 6912584 TI - Educational preparation for nursing. PMID- 6912585 TI - Primary health care - a dream or a reality? PMID- 6912586 TI - Primary health care. PMID- 6912587 TI - Non-governmental organizations and primary health care. PMID- 6912588 TI - AKAP nurses in primary health care TB control program. PMID- 6912589 TI - The primary health care nurse practitioner. PMID- 6912590 TI - Make assertiveness work for you and your patient. PMID- 6912591 TI - Traditional herbal practices and motherhood. PMID- 6912592 TI - [Our part in the health protection of the family]. PMID- 6912593 TI - [Immobilized patient]. PMID- 6912594 TI - [Prevention of fires]. PMID- 6912596 TI - [Nursing process: the diagnosis of nursing care needs]. PMID- 6912595 TI - [Who wants to study by correspondence]. PMID- 6912597 TI - [Rehabilitation in respiratory system diseases]. PMID- 6912598 TI - [Aspects of diet therapy]. PMID- 6912599 TI - [In the admissions office]. PMID- 6912600 TI - [Education program and what else?]. PMID- 6912601 TI - Nurses and personal malpractice insurance. PMID- 6912602 TI - Legal case briefs for nurses. CA: nurse practitioner in coronary lawsuit. AR: male R.N. denied OBS employment. PMID- 6912603 TI - Nurse sues surgeon for malpractice: proof of injury. Case in point: Baldwin v. Williams, M.D., et all (306 N.W.2d 314 - MICH.). PMID- 6912604 TI - Allotypic variants of human C3 and properdin factor B in two French populations Normans and Basques. AB - Human Properdin factor B and C3 polymorphisms are of a real usefulness as genetic markers for population studies. In addition, they are more and more used for the determination of paternity cases. The present communication will be about Bf and C3 allele frequencies in two locally populations of France, Normandy and Western Pyrenees (Basques), The corresponding allele frequencies are as follows, for Normans : Bf(S) = 0.7422, Bf(F) = 0.2285, Bf(F1) = 0.0205, Bf(SO.7) = 0.0088; CsS = 0.788, C3F = 0.204, C3Srare = 0.004, C3Frare =0.004; and for Basques : BfS = 0.5625, BfF = 0.305, BfF1 = 0.1235, BfSO.7 = 0.0075; C3S = 0.7075 and C3F - 0.2925. French Basques are characterized by unusual allele frequencies in European Caucasoid populations for Bf as for C3 genes. A very high incidence of BfF1 allele is reported (BfF1 = 0.125), as previously observed [7, 17]. PMID- 6912605 TI - [Disturbance of exocrine secretion by the human pancreas in hyperlipoproteinemia]. AB - Basal and stimulated (secretin/CCK pancreozymin) duodenal aspirates were analyzed for flow rate and the protein and bicarbonate concentrations in 7 non-alcoholic controls and in 7 subjects with type IV hyperlipoproteinemia. Basal volume and bicarbonate concentration did not differ in the two groups. In the hyperlipoproteinemia patients, basal protein concentration and flow rates were significantly different from controls (p = 0.0143 and p = 0.0182 respectively). The bicarbonate flow rate is also increased in hyperlipoproteinemia. The data obtained after stimulation were similar for protein and HCO3 in both groups. These findings are identical to those observed by SARLES in alcoholic and hypercalcemic animals and in man. It is possible, but not yet proven, that hyperlipoproteinemia pancreatitis is due to protein precipitates in the pancreatic canaliculi. PMID- 6912606 TI - [Interfering tasks: a characteristics problem of hospital work]. PMID- 6912607 TI - [Ergonomic analysis of work space and planning of new hospital units]. PMID- 6912608 TI - [Adapting work to man, in the hospital also]. PMID- 6912610 TI - [Analysis of the total work responsibility of the nurses' aides in an orthopedic unit]. PMID- 6912609 TI - [Birth and development of hospital ergonomics in France]. PMID- 6912611 TI - [A look at nurses' work schedules]. PMID- 6912612 TI - [Education in hospital ergonomics]. PMID- 6912613 TI - [A cycle of continuing education on hospital ergonomics]. PMID- 6912614 TI - [Ergonomics and nursing work]. PMID- 6912615 TI - [Night work: repercussions on health and social life of hospital personnel]. PMID- 6912616 TI - [Information in the hospital service, research and methodology]. PMID- 6912617 TI - [Special electrocardiographic technics: monitoring, exercise test, endocavitary exploration and Holter technic]. PMID- 6912618 TI - [Electrocardiography]. PMID- 6912619 TI - [The normal echocardiogram]. PMID- 6912620 TI - [The electrocardiogram in chest pain]. PMID- 6912621 TI - [Electrocardiographic changes observed in treatment with digitalis, quinidine and diuretics]. PMID- 6912622 TI - [Hospital organization and methods: 2 criteria for quality of diagnosis and nursing care]. PMID- 6912623 TI - [Research on methods for personalizing care]. PMID- 6912624 TI - [Hygiene of food and beverages: departmental health regulations]. PMID- 6912625 TI - [Description of the clinical assessment of children]. PMID- 6912626 TI - [Early diagnosis of cerebral motor disorders]. PMID- 6912627 TI - [A consequence of perinatal cerebral anoxia]. PMID- 6912628 TI - [Role of surgery in orthopedic disorders due to motor disorders of cerebral origin]. PMID- 6912629 TI - [Etiology of cerebral motor disease]. PMID- 6912630 TI - [Principles of rehabilitation in cerebral motor disorders]. PMID- 6912631 TI - [Psychological aspects of cerebral motor disorders]. PMID- 6912632 TI - [The future of cerebral motor-handicapped patients]. PMID- 6912633 TI - [Role of the nurse in cerebral motor disorders]. PMID- 6912634 TI - [Nursing care of a case of cerebral motor handicap. Case report of little Sadouk]. PMID- 6912635 TI - [Practicing the profession of nursing: decree number 81-539 of the 12th of May 1981]. PMID- 6912636 TI - [Towards a proper nursing role]. PMID- 6912637 TI - [Psychological aspects of nursing care of the dying leukemic child]. PMID- 6912638 TI - [Abdominal emergencies revealing biliary lithiasis]. PMID- 6912639 TI - [Not always simple surgery]. PMID- 6912640 TI - [Complications of biliary surgery]. PMID- 6912641 TI - [Hospital admission of the future bile duct surgical patient]. PMID- 6912642 TI - [Anesthesia-rescussitation of a patient operated on for cholelithiasis]. PMID- 6912643 TI - [Diagnostic elements and surgical indications]. PMID- 6912644 TI - [Biliary intervention, role of the circulating nurse]. PMID- 6912645 TI - [Postoperative emergencies]. PMID- 6912646 TI - [Monitoring a patient operated on for cholelithiasis]. PMID- 6912648 TI - [Artificial respiration using a manual respirator of the Ambu type]. PMID- 6912647 TI - [Kehr's drainage]. PMID- 6912649 TI - [Emergency biliary pathology]. PMID- 6912650 TI - [Acute symptoms of biliary lithiasis]. PMID- 6912651 TI - [Intestinal disorders leading to enterostomies]. PMID- 6912652 TI - [Colostomies: technics, preoperative and immediate postoperative care]. PMID- 6912653 TI - [Ostomates]. PMID- 6912654 TI - [Ileostomy technics, preoperative and immediate postoperative care]. PMID- 6912655 TI - [Enterostomy complications]. PMID- 6912656 TI - [Role of the circulation nurse during enterostomies]. PMID- 6912657 TI - [Role of stomatherapy during hospitalization. Stomatherapy consultations]. PMID- 6912658 TI - [Stomatherapy, equipment]. PMID- 6912659 TI - [Practical application of stomatherapy: "care of digestive fistulas or urinary diversion"]. PMID- 6912660 TI - [Diet of stoma patients]. PMID- 6912661 TI - [The "stoma" child]. PMID- 6912662 TI - [Problems of ostomates: study of an actual case]. PMID- 6912663 TI - [Ostomy associations]. PMID- 6912664 TI - [Living with a stoma (equipment and socio-economic problems excluded)]. PMID- 6912665 TI - [Socio-economic consequences of stomas]. PMID- 6912666 TI - [Education of stomatherapists]. PMID- 6912667 TI - [Hanging--strangulation]. PMID- 6912668 TI - [Intestinal physiology in cases of ileostomy or colostomy]. PMID- 6912669 TI - [The anesthesiologist facing prematurity]. PMID- 6912670 TI - [To inform, to monitor, to prevent]. PMID- 6912671 TI - [Role of the nurse in prematurity]. PMID- 6912672 TI - [Problems of prematurity]. PMID- 6912673 TI - [Preventing prematurity. Observation of Mrs. O.L...]. PMID- 6912674 TI - [Epidemiology and mechanisms of prematurity]. PMID- 6912675 TI - [Contribution of the midwife in home monitoring of pregnancies]. PMID- 6912677 TI - [Role of the pediatric nurse in a premature infant department]. PMID- 6912676 TI - [Parent's reception in a neonatology department]. PMID- 6912678 TI - [Lactation and its inhibition]. PMID- 6912679 TI - [Cystitis in women]. PMID- 6912680 TI - [Etiology of prematurity]. PMID- 6912681 TI - [Psychology of pregnant women at risk for premature labor]. PMID- 6912682 TI - ["Normal" escape reaction]. PMID- 6912684 TI - [Multiform reactions to aggression]. PMID- 6912683 TI - [Fugue in the adolescent]. PMID- 6912685 TI - [Pathological escape reactions]. PMID- 6912686 TI - [Escape reactions observed in institutionalized psychiatric patients]. PMID- 6912687 TI - [Introduction to escape reactions]. PMID- 6912688 TI - [Management approach to escape reactions]. PMID- 6912689 TI - [The future of mentally handicapped youth: a dynamic perspective]. PMID- 6912690 TI - [Neuro-physiological mechanisms of escape reactions]. PMID- 6912691 TI - [Kallikrein-kinin system of the blood and bulbar microcirculation in peptide ulcer]. PMID- 6912693 TI - [Nurse among the Indians in Brazil]. PMID- 6912692 TI - The law and your practice. PMID- 6912694 TI - [State special school of psychiatric nursing in Bygdoy]. PMID- 6912695 TI - [Nursing and social anthropology: 2 disciplines with a common starting point]. PMID- 6912696 TI - [What can harm the fetus--tobacco - alcohol - drugs?]. PMID- 6912697 TI - [What is of general interest in the Norwegian Nurses' Association?]. PMID- 6912699 TI - [Study from Tromso: dental care needs for patients in home nursing]. PMID- 6912698 TI - [Chaos in the Polish health system]. PMID- 6912700 TI - [Pastoral care and nursing care]. PMID- 6912701 TI - [NAVF (Norwegian General Scientific Research Council)-seminar in Vettre: specialization in health services in the year 2000]. PMID- 6912702 TI - [Ada Castracane--a "grassroots nurse". Interview by Inger-Sofie Kvamme]. PMID- 6912703 TI - [Graduate education in health education]. PMID- 6912704 TI - [Expense analysis of a combination nursing home and of a nursing home only]. PMID- 6912705 TI - [Legal rights for psychiatric patients improved]. PMID- 6912706 TI - [Shortage of nurses]. PMID- 6912707 TI - [Fear of death and coping strategies]. PMID- 6912708 TI - [Sterilization of women]. PMID- 6912709 TI - [A neglected field: oral hygiene in nursing homes and homes for the aged. Interview by Henry Harm]. PMID- 6912710 TI - [New regulations: dental care of patients in institutions]. PMID- 6912711 TI - [Public endorsement of male nurses: open letter to Anne-Lise Bergenheim]. PMID- 6912712 TI - ["Dangerous" knowledge]. PMID- 6912713 TI - [Care philosophy and care in practice]. PMID- 6912714 TI - [What consequences do the EEC directives have for our work environment?]. PMID- 6912715 TI - [Technological arrangements also of current interest in the field of nursing]. PMID- 6912716 TI - [Danish Nursing Council on government's employment plan: many young persons at work under an expanded public employment policy]. PMID- 6912717 TI - [How does nursing education in the Scandinavian countries agree with nurses' functions in the respective countries? 7. Education coordinates and has common content]. PMID- 6912718 TI - [How does nursing education in the Scandinavian countries agree with nurses' functions in the respective countries? 8. A common goal in education is a condition]. PMID- 6912719 TI - [How does nursing education in the Scandinavian countries agree with nurses' function in the respective countries? 9. Against changes which signify deterioration]. PMID- 6912720 TI - [Social inequality increases in basic education]. PMID- 6912721 TI - Death in the first person. PMID- 6912722 TI - Societal/cultural views regarding death and dying. PMID- 6912723 TI - Care of a hospitalized dying patient. PMID- 6912724 TI - The hospice movement: growing pains and promises. PMID- 6912726 TI - The impact of sudden infant death on the family: nursing intervention. PMID- 6912725 TI - A special Christmas: an account of the last Christmas of Barbara Mackenzie Rogers Hepner. PMID- 6912728 TI - Near-death events and critical care nursing. PMID- 6912727 TI - The patient's need of faith at death. PMID- 6912730 TI - Death education: a continuing process for nurses. PMID- 6912729 TI - Medico-legal considerations and the quality of life. PMID- 6912732 TI - Sudden infant death syndrome--the silent killer. PMID- 6912731 TI - [Effect of proteolysis enzymes and their inhibitors on oxygen uptake by rat brain tissue and its antitryptic activity]. AB - Trypsin in a dose of 3 microgram increases the intensity of oxygen uptake and antitryptic capacity of the brain tissue in animals under study. These indices decrease considerably under the effect of trypsin in a dose of 6-12 microgram. Kallikrein in the same doses has a unidirected stimulating effect. The antitryptic serum and ingitryl block the biological effect of trypsin and similarly to the rabbit normal and antikallikreinic serum stimulate the oxygen uptake. PMID- 6912733 TI - The who, what, when, why and how of professional negotiations for nurses. PMID- 6912735 TI - Continuing education for nurses. PMID- 6912734 TI - Nursing in America. PMID- 6912736 TI - Educating for care: part one of a two part article. PMID- 6912737 TI - Ethics and nursing. PMID- 6912738 TI - The role of the nurse representative. PMID- 6912739 TI - Educating for care. 2. PMID- 6912740 TI - Nurse--you can do so much. PMID- 6912742 TI - Survival of the fittest? PMID- 6912741 TI - Early experience in the provision of university education for qualified nurses. PMID- 6912743 TI - A legal overview of nursing unionization. PMID- 6912744 TI - Nursing research in Virginia. PMID- 6912745 TI - New job--what to expect. PMID- 6912746 TI - Cultural factors in hypertension of Spanish-speakers. PMID- 6912747 TI - Entry into practice: where are we and how did we get here? PMID- 6912748 TI - Tampons and toxic-shock syndrome. PMID- 6912749 TI - Loneliness: being practical about an abstraction. PMID- 6912750 TI - Community education: a hospital commitment. PMID- 6912751 TI - Professionalism - unionism - and the future of nursing. PMID- 6912752 TI - "Health care in the '80's - nursing advocacy role" (gerontology). PMID- 6912753 TI - Clinical privileges for nonhospital-based nurses. PMID- 6912754 TI - Epidural anesthesia for the woman in labor. PMID- 6912755 TI - Graduate nurse transition program. PMID- 6912756 TI - Epidermolysis bullosa: an inherited skin disorder. PMID- 6912757 TI - An exercise class for patients in traction. PMID- 6912758 TI - Getting to the cause of headaches. PMID- 6912759 TI - Dealing with feeling: managing guilt. PMID- 6912760 TI - Programmed instruction: sensory changes in the elderly. PMID- 6912761 TI - Cephalosporin update. PMID- 6912762 TI - The legal side: when a student fails clinical. PMID- 6912763 TI - RN opens office for insurance health assessment. PMID- 6912765 TI - Eye lymphography with Iotasul. PMID- 6912764 TI - Amniotic fluid absorbance at 650 nm: a comparison with fetal lung maturity characteristics. AB - Using the rhesus monkey as an animal model we measured several indices of fetal lung maturation including pressure-volume characteristics and phospholipid concentrations and correlated them with the absorbance of amniotic fluid at 650 nm (A650). Those parameters, which are indicative of the presence of surfactant (i.e., deflation stability, lecithin-sphingomyelin ratio, lung phosphatidylcholine, as well as disaturated phosphatidylcholine), correlate significantly with the amniotic fluid A650, even after correction for gestational age. Maximal lung volume changes, thought to be reflective of alterations in tissue forces, did not correlate with A650. These data in the rhesus fetus indicate that the A650 reflects pulmonary surfactant characteristics independent of gestational age. Accordingly, this test may prove to be an accurate predictor of the risk of the respiratory distress syndrome. PMID- 6912766 TI - [Oxygen consumption and aging in longterm cultures of lens epithelia]. AB - By means of the described technique lens epithelia were cultured in 40 subcultures; at the same time, both the morphological aging processes and oxygen consumption of the cells, were observed using the Warburg respirometer. To date comparable studies are not available. Morphologically, cell enlargement took place in conjunction with signs of degeneration. Oxygen consumption of 2 microliter per hour per 10(5) cells +/- 0.8 remained at a constant level without any significant diurnal rhythm up to subculture 39 and then suddenly fell to about one-fourth of the initial value. As the cells died of an unknown cause, it was concluded that the aerobic metabolism of lens epithelia seemed to be linked to survival without being age related. PMID- 6912767 TI - The CT-topography of retrobulbar anesthesia. Anatomic-clinical correlation of complications and suggestion of a modified technique. AB - The anatomic relationship of an injection needle as traditionally placed in retrobulbar anesthesia to optic nerve, orbital vessels and eye muscles is demonstrated by computed tomography. The clinical complications of retrobulbar injections are reviewed and correlated to the orbital topography in different positions of gaze, as analyzed in anatomic sections and CT images. The results indicate that with the transitional technique of retrobulbar injection the most important orbital structures are in the immediate neighbourhood of the needle. A different injection technique is discussed. PMID- 6912769 TI - [Corneal sensitivity after photocoagulation for diabetic retinopathy]. AB - Corneal sensitivity was determined with the Draeger aesthesiometer in 39 patients with proliferative diabetic retinopathy who underwent treatment with a xenon photocoagulator or argon laser. In 29 patients measurements were performed before and after photocoagulation; in 10 patients the unaffected eye was used for comparison. Statistical evaluation showed a significant difference between the mean values for corneal touch threshold before and after argon laser coagulation. After xenon photocoagulation, corneal sensitivity was reduced in all patients (n = 7). It was shown that corneal sensitivity was significant lower after xenon photo coagulation than with argon laser coagulation. PMID- 6912768 TI - [Measurements of blood flow in retinal vein occlusion]. PMID- 6912770 TI - [Corneal sensitivity after retinal reattachment operation]. AB - The corneal touch threshold (CTT) was determined in 35 eyes before and after retinal reattachment operations. In some cases the CTT of the unaffected eye was taken for comparison. The new aesthesiometer developed by Draeger in 1977 was used and measured CTT in the center of the cornea and in the 12, 3, 6, and 9 o'clock position 1 mm from the limbus. Thirty eyes (86%) showed a rise in CTT after retinal reattachment operations, irrespective of the method of anaesthesia used, and the decrease in corneal sensitivity was observed for up to a period of 5 years postoperatively. Loss of corneal sensitivity was more marked in operations with diathermy and scleral pocketing than in cases with cryopexy and plombage operations. Extremely high CTT values were observed in eyes that underwent encircling procedures, cryopexy, vitrectomy, and gas injection. There was a significantly higher decrease in corneal sensitivity after encircling procedures than after plombage operations. PMID- 6912771 TI - Examination of the fast oscillation of the corneoretinal potential under clinical conditions. AB - The "fast oscillation" of the corneoretinal potential can be precisely examined by means of cyclic light stimuli and an automatic measuring device. This new procedure is carried out during the period of adaptation as part of the usual EOG test. Normal values and some clinical findings are presented. The fast oscillation may provide additional information when compared with EOG and ERG results. PMID- 6912773 TI - Glaucomatouslike visual field defects in chronic papilledema. AB - In 19 patients, 31 eyes with chronic papilledema were found to have visual field defects other than enlarged blind spots. In this series, the inferior nasal quadrant was most frequently involved. Dense paracentral scotomata were found in the Bjerrum area, some of which later progressed to form ring scotomata. Visual acuity usually deteriorated late in the course of the disease. The similarities of visual field defects in papilledema and glaucoma suggest common pathogenetic mechanisms of nerve fiber atrophy in both diseases. PMID- 6912772 TI - [Relation of color-coordinate transposition in temporal papillary pallor to visual acuity]. AB - The authors first described the method of fundus color measurement by visual comparison in 1974, and by its use the clinician is able to follow the development of optic disc atrophy or diseases in which hyperemia is seen by using quantitatively defined color coordinates. Color coordinates of the nasal and temporal papillary halves in 100 normal eyes are demonstrated in the x and y plane. The palor range in atrophy is in the upper left part of the scale in comparison to normality. The mathematical relationship between visual acuity and temporal papillary palor is demonstrated in a defined group of 98 eyes. A formula has been derived with which the probable visual acuity can be calculated from the measured color coordinates and its clinical use is described. PMID- 6912774 TI - Guidelines for the investigation function of nursing. PMID- 6912775 TI - Rapid purification of a prekallikrein from rat pancreas. PMID- 6912776 TI - Emphysema induced in vitro and in vivo in dogs by a purified elastase from homologous leukocytes. AB - The protease hypothesis of emphysema development evolved from systems using intratracheal instillation or aerosols of heterologous enzymes, such as papain or porcine pancreatic elastase, which bear no relation to the animal species treated. Although these enzymes did produce experimental emphysema, their exogenous origin and superphysiological dosages limit their use in definitive model systems. The observation that dog leukocyte homogenates could induce canine emphysema led us to purify the causative agent from canine neutrophils. This report establishes that a single elastolytic enzyme from dog neutrophils is responsible for inducing experimental emphysema in the dog. Two purification methods were employed. The first used solvents of increasing ionic strength in a sequential extraction of acetone powders of purified dog neutrophils. The ability to initiate emphysema-like lesions was tested in every fraction of the purification and was localized in the extract with the highest true elastolytic activity. The second purification involved neutrophil intracytoplasmic organelle fractionation and established that only extracts of the lysosomal granules were capable of emphysema induction. Finally, the enzyme was purified to homogeneity from the granules using affinity chromatography and was shown to be a true elastase. Emphysema development was quantitated using mean linear intercept and was shown to be dependent on elastase concentration. There does not appear to be any other single enzyme in the canine neutrophil capable of inducing experimental emphysema. PMID- 6912777 TI - Susceptibility of pneumococci to 14 beta-lactam agents: comparison of strains resistant, intermediate-resistant, and susceptible to penicillin. AB - To measure the susceptibility of penicillin-resistant pneumococci to newer beta lactam agents, we evaluated 54 selected strains recovered from patients with bacteremia or meningitis. Three groups of pneumococci were tested: penicillin susceptible strains, strains with intermediate penicillin resistance, and penicillin-resistant strains. Minimal inhibitory concentrations of benzyl penicillin, oxacillin, cephalothin, cefamandole, cefoxitin, moxalactam (LY127935), cefotaxime (HR756), piperacillin, pirbenicillin, N-formimidoyl thienamycin (MK0787), cefoperazone (T1551), mezlocillin, azlocillin, and mecillinam were determined. For all groups of pneumococci tested, cefotaxime, and particularly thienamycin, had the greatest activity. Piperacillin, mezlocillin, and azlocillin had activity similar to that of benzyl penicillin. Cefoperazone had less activity than penicillin against strains with penicillin minimal inhibitory concentrations of less than 1 microgram/ml but greater activity than penicillin against strains with greater resistance. Oxacillin, cephalothin, cefamandole, and pirbenicillin all had less activity for each group of pneumococci tested; moxalactam, cefoxitin, and mecillinam had the least activity. The relative differences in susceptibility to penicillin of each group of pneumococci tested were similar for each of the beta-lactam agents tested. The clinical effectiveness of cefotaxime and thienamycin for therapy of disease due to penicillin-resistant pneumococci needs further evaluation, and of particular interest will be the levels of these drugs which can be achieved in cerebrospinal fluid. PMID- 6912778 TI - Working to change physician's image of OR nurses' role. PMID- 6912779 TI - Jerry Peers to retire in 1983. PMID- 6912781 TI - Commitment needed for effective staff orientation program. PMID- 6912780 TI - What really catches your eye in job recruitment ads? PMID- 6912782 TI - OR staffs respond to Hyatt casualties. PMID- 6912783 TI - A teaching plan for external fixation. PMID- 6912784 TI - Perioperative care of myasthenic patients. PMID- 6912785 TI - The first day in surgery. PMID- 6912786 TI - Electroconvulsive therapy: an effective treatment. PMID- 6912787 TI - Evaluating surgical gowning, draping fabrics. PMID- 6912788 TI - Establishing a stroke cluster in a skilled nursing facility. PMID- 6912789 TI - Understanding pressure sores. PMID- 6912790 TI - Vanadium in photosynthesis of Chlorella fusca and higher plants. AB - The influence of vanadium compounds (vanadate, vanadyl citrate) on photosynthesis in Chlorella fusca and in algal and spinach chloroplasts has been investigated. It was found that: 1. At moderately high concentrations (at least 0.1 mM) both vanadate and vanadyl citrate enhance photosynthetic O2 production in intact C. fusca cells. At lower V concentration (about 2 microM) only vanadate stimulates photosynthesis. The increase is dependent on culture conditions and on light intensity. 2. Up to 1 mM V, neither vanadium compound influences PS II activity, either in intact cells or in algal or spinach chloroplasts. 3. The PS I reaction in algal and spinach chloroplasts is maximally enhanced (3-fold) in presence of vanadium (20 microM). The increase is independent of light intensity. 4. Cr(VI), Mo(VI), and W(VI) (1 mM) stimulate photosynthesis in intact C. fusca cells, but do not influence the photosystems of isolated chloroplasts. Vanadium is suggested to act as a redox catalyst in the electron transport from PS II to PS I. PMID- 6912791 TI - Transfer RNA in reticulocyte maturation. AB - The disappearance of tRNA during the maturation of rabbit reticulocytes under the stress of phenylhydrazine-induced hemolysis was studied. The tRNA content of reticulocytes and of erythrocytes derived from them was compared. The results show that tRNA persists longer after reticulocyte maturation than ribosomes and than the ability to incorporate amino acids into protein. Considerable uniformity of tRNA degradation was noted with about 15% of the tRNA for most amino acids remaining after reticulocyte maturation. The half-life of tRNA in the maturing cells is estimated to be 50--60 h. There is little tRNA lacking the 3'-terminal pCpCpA moiety in cells derived from reticulocytes. PMID- 6912792 TI - [Inhibition of kininogenase activity of cathepsins D by acid-resistant proteinase inhibitor from rabbit serum]. AB - The inhibitory effect of thermo- and acid-resistant inhibitor of trypsin, chymotrypsin and leukocyte proteinases (TASPI) from rabbit serum on the kininogenase activity of cathepsins D from different organs and tissues (human spleen and liver, chicken liver, spleen leukemic infiltrate from patients with myeloid leukemia) was revealed. The progressive mechanism of TASPI and cathepsins D complexation dependent on time and temperature was revealed. The rate constant of inhibition (ki) of chicken liver cathepsin D by TASPI at 37 degrees was 4,25.10(3)M-1 min-1. It was shown that the kininogenase activity of chicken liver cathepsin D was slightly inhibited by the basic pancreatic trypsin and kallikrein inhibitor from bovine organs (Kunitz type) and by soya bean trypsin inhibitor. The role of TASPI as regulator of cathepsins D activity under pathological conditions accompanied by lysosomal disintegration is discussed. PMID- 6912794 TI - But, would you want your daughter to become a nurse? Part one. PMID- 6912793 TI - Nursing in Canada's Armed Forces. PMID- 6912795 TI - Short stay assessment and treatment units, can they help? PMID- 6912796 TI - It's lonely in the library. PMID- 6912797 TI - Beginnings: a study of a group of new practitioners. PMID- 6912798 TI - Structure and properties of a bovine liver UGA suppressor serine tRNA with a tryptophan anticodon. AB - A bovine liver serine tRNA with a variety of unusual features has been sequenced and characterized. This tRNA is aminoacylated with serine, although it has a tryptophan anticodon CmCA. In ribosome binding assays, this tRNA (tRNASERCmCA) binds to the termination codon UGA and shows little or no binding in response to a variety of other codons including those for tryptophan and serine. The unusual codon recognition properties of this molecule were confirmed in an in vitro assay where this tRNA suppressed UGA termination. This is the first naturally occurring eucaryotic suppressor tRNA to be so characterized. Other unusual features, possibly related to the ability of this tRNA to read UGA, are the presence of two extra nucleotides, compared to all other tRNAs, between the universal residues U at position 8 and A at position 14 and the presence of an extra unpaired nucleotide within the double-stranded loop IV stem. This tRNA is also the largest eucaryotic tRNA sequenced to date (90 nucleotides). Despite its size, however, it contains only six modified residues, tRNASerCmCA shows extremely low homology to other mammalian serine (47-52% homology) or tryptophan (49% homology) tRNAs. PMID- 6912800 TI - Cancer: put the blame where it lies. PMID- 6912799 TI - Isolation and characterization of a low molecular weight complement inhibitor present in normal human serum. AB - Normal human serum and urine were found to contain a low molecular weight complement inhibitor (LMWI). LMWI was separated from serum by dialysis in membrane tubing or through an Amicon PM10, and then concentrated on an Amicon UM05 membrane. On Bio-Gel P-2 filtration, LMWI was eluted just after the column calibration marker, stachyose hydrate (6666 . 6 daltons), and was estimated to be 500 daltons. Both pathways of complement activation were susceptible to modulation by LMWI. Addition of LMWI reduced the haemolysis of sheep erythrocytes sensitized with antibody, rabbit erythrocytes and guinea-pig erythrocytes bearing human C3 and C4. Formation of EAC142 from EAC14 and guinea-pig C2 was blocked, indicating a failure to generate the classical pathway C3 convertase: however, the lysis of preformed EAC142 was not suppressed. Conversion of factor B and C3 did not occur when LMWI was present during zymosan activation of serum. This indicates that the inhibitor either prevented, or acted at a step prior to, the cleavage of factor B by factor D. LMWI did not prevent formation of erythrocyte C567 intermediates nor their subsequent lysis by C8 and C9. Thus, serum contains a 500-dalton inhibitor which modulates the activities of both complement pathways at an early step in each of the activation sequences. LMWI may serve as a regulator of the inflammatory process by suppressing C3 convertase formation and generation of complement-derived, biologically reactive molecules. PMID- 6912801 TI - Severe toxic and allergic reactions to insect bites and stings. PMID- 6912802 TI - Inline I.V. filters. PMID- 6912803 TI - Tumor cell kinetics and cancer chemotherapy. PMID- 6912804 TI - EKG manifestations of digitalis toxicity. PMID- 6912805 TI - A case for alternative options for registered nurses in baccalaureate education. PMID- 6912806 TI - Advocacy--risk and reality. PMID- 6912807 TI - Clinical education of nurse students: an overlooked element. PMID- 6912808 TI - Nursing service expectations of new graduates. PMID- 6912809 TI - Can you really write? PMID- 6912810 TI - NSNA path to professional identity. PMID- 6912811 TI - The adult with congenital heart disease. PMID- 6912812 TI - Cryoglobulinemia. PMID- 6912813 TI - [Nursing care in chemotherapy]. PMID- 6912814 TI - [The importance of research in nursing]. PMID- 6912815 TI - Protein synthesis in brine shrimp embryos. Regulation of the formation of the ternary complex (Met-tRNAf X eIF-2 X GTP) by two purified protein factors and phosphorylation of Artemia eIF-2. AB - We have purified from the ribosomal wash of dormant and developing embryos of Artemia two proteins, Co-eIF-2(A) and Co-eIF-2(B). These factors are essential for ternary complex formation and binding of [35S]-Met-tRNAf to 40-S ribosomal subunits with 15-30 microgram eIF-2/ml of reaction mixture. On polyacrylamide gel electrophoresis in dodecylsulfate, Co-eIF-2(A) is composed of a single polypeptide of Mr 65 000, whereas Co-eIF-2(B) contains polypeptides of Mr 105000 and 112000. Co-eIF-2(A) is sensitive to 4.5 microM aurintricarboxylic acid but Co eIF-2(B) requires approximately 15 microM aurintricarboxylic acid to give 50% inhibition of ternary complex formation. The stimulatory activity of both factors is abolished by pretreatment of the proteins with N-ethylmaleimide. Artemia eIF-2 rapidly bonds [3H]GDP or [3H]GTP and at 15 degrees C the initiation factor rapidly equilibrates bound nucleotides with free GDP or GTP. Both Co-eIF-2(A) and Co-eIF-2(B) have no effect on the exchange or the amount of nucleotide bound. The small subunit (Mr 43 000) of Artemia eIF-2 is phosphorylated in the presence of the rabbit reticulocyte heme-repressible kinase. Tryptic digestion of [32P]phosphorylated eIF-2 produces a single major phosphopeptide and several minor ones. Acid hydrolysis of these phosphopeptides, as well as of [32P]phosphorylated eIF-2, demonstrates that the radioactivity is predominantly associated with phosphoserine. Phosphorylated Artemia eIF-2 is active in ternary complex formation, in AUG-dependent binding of [35S]Met-tRNAf to 40-S ribosomal subunits and in cell-free protein synthesis. Both Co-eIF-2(A) and Co-eIF-2(B) stimulate ternary complex formation with phosphorylated eIF-2. A kinase that phosphorylates the small subunit of eIF-2 is present in the post-ribosomal supernatant as well as in the ribosomal wash of developing Artemia embryos. PMID- 6912817 TI - A radioimmunoassay for the detection of molecular forms of human plasma kininogen. PMID- 6912816 TI - The localization of kallikrein in the dog and guinea-pig submandibular glands. AB - In the dog and guinea-pig submandibular glands kallikrein seems to be present in the striated duct cells. Following sympathetic nerve and in vivo isoproterenol stimulation of the dog and guinea-pig submandibular gland respectively, there is a reduction of kallikrein concentration. Ultrastructurally this reduction corresponds to the decrease of straited duct secretory granules in both species. Parasympathetic stimulation also causes some release of kallikrein from both species. PMID- 6912818 TI - The sequence of mitochondrial arginine tRNA (anticodon UCG) from a transplantable rat tumor, Morris hepatoma 5123D. PMID- 6912820 TI - A science of nursing--to be or not to be? PMID- 6912819 TI - Properdin factor B polymorphism in continental Italy and Sardinia. AB - A sample of healthy unrelated individuals (882 from Continental Italy and Sicily, and 139 from Sardinia) were typed for HLA and Bf polymorphisms. Bf gene frequencies in Continental Italy and Sicily show an intermediate position among European populations, with Lapps on one side and Basques on the other side; while a very peculiar pattern is observed among Sardinians, with an impressive similarity with French Basques and with the highest F1 gene frequency so far observed. The HLA:Bf gametic associations in Italy and Sardinia are also reported, which confirm the different ethnic background of these populations. PMID- 6912821 TI - The nursing journal--learning resource, professional symbol, and commodity. PMID- 6912822 TI - Assessing the impact of chronic childhood illness on the family and parent coping. PMID- 6912823 TI - Nursing research outside academia: a panel presentation. PMID- 6912824 TI - Perspectives on poverty. PMID- 6912825 TI - A model for parent education. PMID- 6912826 TI - [And the nurse doesn't escape from it...]. PMID- 6912827 TI - [Tele-nursing in Quebec via the Anik B satellite]. PMID- 6912828 TI - [Confusion in the elderly person]. PMID- 6912829 TI - [A nurse's career in the Canadian Armed Forces]. PMID- 6912830 TI - [We don't have the time]. PMID- 6912831 TI - Nursing for a new century: a future framework. PMID- 6912832 TI - Six days, six thousand nurses, and the next one hundred years. PMID- 6912833 TI - ICN watchword 1981-1985. PMID- 6912834 TI - Nursing management of the pediatric patient with Kawasaki's disease. PMID- 6912835 TI - Early detection of hearing impairment. PMID- 6912836 TI - Pediatric cardiology: stressors, reactions, and interventions. PMID- 6912837 TI - Nurses' and physicians' recognition and reporting of child abuse. PMID- 6912838 TI - Siblings: the forgotten grievers. PMID- 6912839 TI - The childbearing experience: a prototype for the study of continuity of care. PMID- 6912840 TI - [Psychological aspects in counseling for preventive agents]. PMID- 6912841 TI - [Parent preparation courses - can one risk to tell about abnormalities and fetal death?]. PMID- 6912842 TI - [Diabetes--pregnancy. An interview study of womens' experience of the problems it causes]. PMID- 6912843 TI - [Evaluation of mothers' education with psychoprophylaxis as delivery preparation in Orebro]. PMID- 6912844 TI - [Encounter and activities in sex education for youth--a RSFU-course]. PMID- 6912845 TI - [Symphysiotomy]. PMID- 6912847 TI - [Pithivier clinic. Impressions from a study visit Sept. 1980]. PMID- 6912846 TI - [Sudden infant death--a puzzle about to be solved]. PMID- 6912848 TI - [Holland--country for home deliveries]. PMID- 6912849 TI - [Acute appendicitis during pregnancy]. PMID- 6912850 TI - [Collection of answers of group discussion questions on the "psychological aspects in delivery routines"]. PMID- 6912851 TI - [Women's experience of their childbirth under epidural anesthesia--a questionnaire study. June--August 1980]. PMID- 6912852 TI - [Journey to Bangladesh]. PMID- 6912853 TI - [Fetal diagnosis from the parents' perspective]. PMID- 6912854 TI - [Impressions from the congress in psychosomatic obstetrics and gynecology]. PMID- 6912855 TI - [Fewer abortions--certainly, but how?]. PMID- 6912856 TI - [Assessment of fetal maturity]. PMID- 6912858 TI - [Finnish study: effect of a breast-feeding campaign by BB]. PMID- 6912857 TI - [What happens with computers in health care?]. PMID- 6912859 TI - [Perinatal infant death and grief--various observations by a hospital clergy person]. PMID- 6912860 TI - Treatment of gentamicin-resistant Klebsiella urinary tract infections with cephradine, augmentin, cefuroxime and amikacin. PMID- 6912861 TI - The role of bovine high-molecular-weight (HMW) kininogen in contact-mediated activation of bovine factor XII: interaction of HMW kininogen with kaolin and plasma prekallikrein. AB - Previous studies from our laboratories (Sugo et al. (1980) Biochemistry 19, 3215 3220) have shown that bovine high-molecular-weight (HMW) kininogen remarkably accelerates the kaolin-mediated activation of Factor XII in the presence of prekallikrein, and that both fragment 1.2 and the light chain regions located in the COOH terminal half of the kininogen molecule are essential for the activation. In the present study, we demonstrate that the accelerating effect of HMW kininogen is mediated through its adsorption on the kaolin surface through the fragment 1.2 region and its complex formation with prekallikrein through the light chain region. The evidence is as follows: 1. HMW kininogen radio-labeled with 125I was adsorbed on kaolin and the adsorption was inhibited by the prior treatment of kaolin with fragment 1.2, fragment 1.2-light chain, kinin-free protein or HMW kininogen, but not with kinin- and fragment 1.2-free protein, light chain or low molecular-weight (LMW) kininogen. 2. The complex formation of HMW kininogen with prekallikrein in bovine plasma or in the purified system was examined by gel-filtration on a column of Sephacryl S-200 In bovine plasma, prekallikrein was eluted in the same fraction as HMW kininogen, showing an apparent molecular weight of 250,000, whereas purified prekallikrein was eluted in the fraction corresponding to an apparent molecular weight of 100,000. When purified prekallikrein was mixed with purified HMW kininogen in a mol ratio of 1 to 2, all prekallikrein was found to be associated with HMW kininogen. Furthermore, purified prekallikrein mixed with kininogen derivatives, such as kinin- and fragment 1.2-free protein, fragment 1.2-light chain or light chain, was eluted in the higher molecular weight fraction. HMW kininogen did not form a complex with prekallikrein. Using the same technique, it was shown that kinin- and fragment 1.2-free protein forms a complex not only with prekallikrein but also with kallikrein. PMID- 6912863 TI - Body experience during pregnancy. PMID- 6912862 TI - Stimulation of the elastolytic activity of leukocyte elastase by leukocyte cathepsin G. AB - Human leukocyte cathespin G strongly stimulates the rate of solubilization of human lung elastin by human leukocyte elastase. For instance, the elastolytic activity of an equimolar mixture of elastase and cathepsin G is more than 5 times higher than that of elastase alone. Optimal stimulation occurs only if cathepsin G and elastase act simultaneously on elastin. Potentiation of leukocyte elastase digestion of lung elastin may also be brought about by bovine alpha-chymotrypsin. This enzyme is about half as efficient as cathepsin G. Stimulation of leukocyte elastase activity by cathepsin G is about 3 times less pronounced with bovine ligamentum nuchae elastin than with human lung elastin. On the other hand, the elastolytic activity of porcine pancreatic elastase is only enhanced by 20 to 30% by cathepsin. Therefore, maximal potentiation of elastolysis occurs with the lung elastin/leukocyte elastase system. The pathologic relevance of these findings is discussed. PMID- 6912865 TI - Home versus hospital delivery: issues and perspectives. PMID- 6912864 TI - Techniques for reducing the need for an episiotomy. PMID- 6912866 TI - The ethics of being a female patient and a female care provider in a male dominated health-illness system. PMID- 6912867 TI - Nursing concerns for patients undergoing mastectomy. PMID- 6912868 TI - Culturally-induced stress during childbearing: the Pilipino-American experience. PMID- 6912869 TI - Intrapartum management of the large infant. PMID- 6912870 TI - Routine care of the normal neonate. PMID- 6912871 TI - Navajo nursing homes: conflict of philosophies. PMID- 6912872 TI - Working with the elderly in a life review group. PMID- 6912873 TI - Knowledge about hypertension in affected elderly persons. PMID- 6912874 TI - Seniors helping seniors: training older adults as new personnel resources in home health care. PMID- 6912875 TI - Developmental patterns of blood pressure and urinary protein, kallikrein, and prostaglandin E2 in Dahl salt-hypertension-susceptible rats. AB - S and R female rats were raised on a 1% NaCl diet, and excretion rates of urinary protein, kallikrein esterase activity, and PGE2 were measured (1) at 1 1/2 months of age, when both S and R rats were normotensive, (2) at 3 months of age, when S rats were mildly hypertensive and R controls remained normotensive, and (3) at 6 months of age, when S rats were markedly hypertensive relative to the still normotensive R rats. Urinary protein excretion rate in S compared to R rats was slightly elevated at 1 1/2 months of age and greatly elevated at 3 and 6 months of age. Urinary kallikrein was measured by hydrolysis of TAME after separation of kallikrein from nonkallikrein TAME esterases on DEAE-Sephadex minicolumns. Kallikrein TAME esterase activity was the same in 1 1/2-month-old S and R rats but became reduced in S relative to R rats at 3 and 6 months of age, concomitant with the development of hypertension and marked proteinuria. Urinary PGE2 was decreased in S rats as compared to R rats at all ages, and therefore the strain difference in urinary PGE2 preceded the development of strain differences in blood pressure and urinary kallikrein activity. We conclude that (1) reduced excretion of urinary kallikrein TAME esterase activity in S rats is probably secondary to hypertension and severe proteinuria and (2) decreased urinary PGE2 excretion in prehypertensive S rats is compatible with, but does not prove, the presence of a primary defect in intrarenal PGE2 production that could be involved in initiating hypertension. PMID- 6912876 TI - Making the most of meetings. AB - When used effectively, meetings can provide a mechanism for integrating different viewpoints, improving the decision-making process, generating new ideas, and coordinating the activities of participants. To be effective, meetings need to be conducted in an organized way by using an agenda, starting and ending on time, facilitating productive participation of members, and by summarizing the work which was accomplished. The following list includes several points to make the most of meetings: 1. Explore alternatives to meeting--telephone, conference call, memorandum. 2. Limit attendance to only those people who have to be there. 3. Make sure all participants know the purpose of the meeting in advance. 4. Send a written agenda in advance of the meeting. 5. Make sure there is a leder who will assume responsibility for starting, guiding, and closing the meeting with a summary. 6. Choose an appropriate place, conveniently located. 7. Choose an appropriate time--afternoon is usually the best. 8. Designate a recorder to make note of decisions, actions, and recommendations. 9. Start and end on time. 10. Stick to the agenda--don't get distracted by side issues which eat into time allotted for the meeting. 11. Control interruptions such as telephone calls for members, or people coming in and out. 12. Make sure everyone is clear about what is expected of them after the meeting. PMID- 6912877 TI - Nursing: healing in a feminine mode. PMID- 6912878 TI - Practice-based research: assessing your department's readiness. PMID- 6912879 TI - Nurse-intern programs: how they're working. AB - Results of the study support conclusions drawn from the literature: The nurse intern program stands as an efficient, effective method of orienting new graduate nurses in their first work experience. Internships provide a highly realistic vehicle for smoothing the transition from student to staff nurse and also promote recruitment and retention of qualified personnel. Participation in an intern program helps the graduate assume increasingly responsible roles as he or she gains self-confidence, competence, and comfort in the clinical setting and becomes more able to give quality patient care. Strong similarities among programs as noted in both the study and the literature suggest that despite differences in titles and settings for these programs, many commonalities do exist. A common feature seems to be the placement of a limited number of participants in one or two areas for a lengthy period under the guidance of a specified individual. This overall structure, in conjunction with a well developed plan of program objectives and experiences, appears to constitute the formula for success. Agencies considering development of a nurse-intern program would do well to first consider their ultimate goal in establishing such a program. Realistic assessment of the agency's capabilities and resources in relation to this desired end will help set the tone for subsequent program planning and minimize future frustration. For a program of this type, support from all levels of administration is essential, since the hoped-for return on investment may be some time in coming. PMID- 6912880 TI - Science as a way of knowing. PMID- 6912881 TI - A system for using supplemental staff. AB - This article has outlined the development of a system for using temporary nurses. Steps in this process include reevaluation of department philosophy; formulation of criteria for temporary staffing; development of scheduling mechanisms and policies that reflect the criteria; and finally, the development of methods for evaluation. Our system uses scheduling components previously in existence at Rush Presbyterian-St. Luke's Medical Center. We consider the computerized system an advantage for our purposes, but it was not essential. A written schedule could then be used to meet department needs. Defining goals and then determining methods is important, since several alternative methods might be possible to meet a goal. Our system emphasizes both continuity and accountability at the unit level. Because the unit leaders have close association with temporary staff, their input is vital. The unit leaders formally evaluate the temporary personnel and are accountable for making appropriate requests for temporary staff. The judgment of need is based on such factors as patient needs, budget allocation, and staff vacations. The system outlined was the necessary by-product of the interfacing of two staffing methods, permanent and temporary. Consistency is the key to resolving problems. PMID- 6912882 TI - Circulating immune complexes and complement levels in hemophilic children. AB - Immune complexes and complement levels were assayed in sera from a group of 69 hemophilic children. Using the Raji cell radioimmune assay and the C1q binding assay, abnormally high levels of circulating immune complexes were rarely found in the group of hemophiliacs which did not differ statistically from the control population. These results do not exclude the presence of low and transient levels of immune complexes in the circulation, but indicate that hemophiliacs are not exposed to increased immune complex loads similar to those found in immune complex diseases. By contrast frequent abnormalities of the complement system were found. Complement levels were elevated in a large percentage of patients, reaching statistical significance for C3, C4, C5, Factor B and Properdin. Levels of the C3 breakdown product C3d were significantly raised suggesting intravascular complement activation. The significance of these abnormalities is discussed in relation to perfusion of Factor VIII preparations. PMID- 6912883 TI - [Mechanism of bacterial drug resistance]. PMID- 6912884 TI - [Combination of antibacterial agents]. PMID- 6912885 TI - Feeding infants with cleft lip and/or palate. PMID- 6912886 TI - First-trimester prenatal counseling in private practice. AB - The future of first-trimester prenatal counseling in private practice is as bright as office nurses choose to make it. Currently, counseling of this kind is being offered only at two places, the Sunnyside office and at the office of another obstetrician whose nurse was trained for counseling by the author. A huge network of private practice counseling is possible, however, if office nurses would learn these skills. Despite some reports of opposition, many physicians would welcome nurses in this counselor's role. A 1972 survey of obstetrician gynecologists showed that 51% favored delegating more tasks to the office nurse, if only to free the physicians's time to see additional patients. According to the physicians surveyed, the "maternity nurse could perform many of the prevention and counseling routines" the physicians felt took up roughly 75% of their office time. First-trimester prenatal counseling in private practice is not only possible in a structured, group-oriented sense, but it is necessary and worthwhile as well. Patients have become increasingly aware of their rights as consumers of health care. Where they get their information-and how accurate and complete it is-is largely up to the nursing profession. PMID- 6912887 TI - Pelvic examination: patient safety and comfort. PMID- 6912889 TI - A couvade: a review. PMID- 6912888 TI - Are normal patients at risk during pregnancy? PMID- 6912890 TI - The process of change: a case study. PMID- 6912891 TI - Maternal attachment of high-risk mothers with well newborns: a pilot study. PMID- 6912892 TI - Needs of cesarean birth parents. PMID- 6912893 TI - Need priorities of adrenalectomy patients as perceived by patients, nurses, and physicians. AB - Patients in this study identified needs they considered important. Perceived need priorities of adrenalectomy patients need to be identified and met both pre- and postoperatively by health team members. Patient-centered nursing and medical conferences should be arranged to provide comprehensive patient care. Establishment of guidelines, based on need priorities perceived by the patient, will provide a master care plan which can assist nurses and physicians in meeting patient needs. These guidelines are important since patients need not only an immediate care plan, but also a long-term plan of care designed to meet individual needs and ever-changing problems of the long-term illness. The study findings show that patients, nurses, and physicians differ in their perception of need priorities of adrenalectomy patients. Nurses and physicians must take heed of patient concerns. Nurses, especially, must realize the needs of the patient in order to provide support, counseling, and education. The necessity for total awareness of patients' needs and perceptions is illustrated by one cancer patient's comments: "Although the disease was diagnosed early and responded successfully to treatment, there was a numbness and fear, the cold chills that accompanied the awareness of the diagnosis and later the altered perception of life, of friends and associates that grew out of the realization that death was never far away. "A human organism with a malignant neoplasm is more than a body with a disease. It is also a reacting individual who has feelings about his illness, and these feelings influence the way he perceives his medical personnel and utilizes his advice and care." It is important that all members of the health team acquire a better understanding of the various need theories and the importance of perceiving the needs of patients as the patient perceives them. In addition, it is essential for health team members to continually refer to the relevant literature concerning needs to improve the quality of total patient family care. PMID- 6912894 TI - Effectiveness of prenatal and postnatal instruction in postpartum care. PMID- 6912895 TI - Change in concerns of first-time mothers after one week at home. PMID- 6912896 TI - [Technology and humaneness in obstetric and gynecologic care]. PMID- 6912897 TI - [Multiple sclerosis and pregnancy]. PMID- 6912898 TI - [Music and the unborn infant]. PMID- 6912900 TI - [Public health care for mothers and children in the Soviet Union]. PMID- 6912899 TI - [Conditions of families with children at home and abroad]. PMID- 6912901 TI - [3-months colic and allergic reactions to certain foods]. PMID- 6912902 TI - [HYpertension in pregnancy]. PMID- 6912903 TI - [Digestion of fat and protein and its relation to the activity of faecal enzymes in mucoviscidosis infants under substitution therapy with pancreatic enzymes (author's transl)]. AB - The article reports on a study to determine the influence of different dosage schedules of a pancreas enzyme preparation on the digestion of fat and protein and on the lipolytic, tryptic and chymotryptic activity of the faeces in children suffering from mucoviscidose. After administration of the pancreatin preparation at the low dose level, the quantity of faeces, the excretion of fatty acids and of nitrogen are reduced and the absorption coefficient is improved. The faecal tryptic and chymotryptic activity increases, whereas the lipase activity in the faeces merely shows a tendency to rise. Increasing the pancreatin dose up to a still tolerable value by doubling the dosage does not result in further reduction of the excretion of fat and nitrogen although it enhances the proteolytic activity of the faeces while the lipase activity remains unaffected. Determination of the lipolytic, tryptic or chymotryptic activity is, therefore, unsuitable for assessing the fat and protein digestion and for estimating the required dose of pancreatic enzyme. No increase in uric acid excretion was seen in the urine collected for 24 hours after administration of both enzyme doses. PMID- 6912904 TI - [Kallikrein-kinin and blood coagulation in traumatic shock]. PMID- 6912906 TI - [Suggestions for the development of rehabilitation nursing]. PMID- 6912905 TI - [Action on the education of rehabilitation workers]. PMID- 6912907 TI - [Symbolic interaction theory and psychiatric nursing]. PMID- 6912908 TI - [The theory and practice of "therapeutic limitation" in child psychiatric nursing]. PMID- 6912909 TI - [A survey on current health care activities of the aged in a selected urban area]. PMID- 6912910 TI - [A study on the determinants of utilization of community health resources in Jeon Buk area]. PMID- 6912911 TI - [Analysis of the relationship between acceptance of menstruation and self-concept -according to middle and high school girls of a certain region]. PMID- 6912912 TI - [IVAC persistent infusion pump]. PMID- 6912913 TI - [Breastfeeding as prevention]. PMID- 6912914 TI - [Breastfeeding in spite of environmental pollution?]. PMID- 6912915 TI - [Medical aspects of air rescue]. PMID- 6912916 TI - [Therapeutic communication is part of nursing. Key point of the Berlin continuing education congress for nurses]. PMID- 6912918 TI - [Male slang in the OR]. PMID- 6912917 TI - [Hospital and work safety legislation]. PMID- 6912919 TI - State nursing associations and collective bargaining: a conflict of interest? PMID- 6912920 TI - Understaffing: living with the reality. PMID- 6912921 TI - Disclosure of injury and illness: responsibilities in the physician-patients relationship. PMID- 6912922 TI - Women's perceptions of their important dyadic relationships during pregnancy. AB - This study examined women's perceptions of important relationships during pregnancy. Fourteen women were interviewed at approximately monthly intervals from the third through the last month of their pregnancies. During these interviews, each woman (a) identified relationships which were important to her; (b) described each important relationship as either changing or stable; and (c) evaluated each important relationship as either satisfactory or unsatisfactory. Study results indicate that the women identified important relationships with their husbands, children, parental figures, and peers. Important relationships were described as more changing than stable throughout pregnancy. These relationships were experienced, over all, as more satisfactory than unsatisfactory. An analysis of the perceived satisfactory and unsatisfactory relationships reveals the woman's expectations for important relationships and indicates major considerations for the acceptance and accommodation process. The woman's expectations for her important relationships indicate the presence of two major systems of relationships within her social space. Each of these systems is characterized by a dominant function. One system of relationships has as its primary function, differentiation; the other, support. Within the differentiation system, the woman helps important others to reorganize for the addition of the expected baby to the family system. Within the supportive system, the pregnant woman is the recipient of the nurturing and caring actions of others. The interplay between these interdependent systems reflects the workings of the task of accommodation and acceptance. PMID- 6912923 TI - Reactions of an adolescent girl during the initial period of treatment of a neoplastic disease. PMID- 6912924 TI - Psychological upset in posthospitalized children: a review of the literature. PMID- 6912926 TI - The review and grief work of a multipara upon birth of a live infant. PMID- 6912925 TI - Maternal responses to an infant with cleft lip and palate: a review of literature. PMID- 6912927 TI - [Effect of adverse biological factors on the neuropsychological health of children and adolescents]. PMID- 6912928 TI - [Chronic kidney failure]. PMID- 6912929 TI - [Therapeutic nutrition in kidney diseases in children]. PMID- 6912930 TI - [Kasha in infant nutrition]. PMID- 6912932 TI - [Early detection of congenital dysplasia of the hip joint]. PMID- 6912931 TI - [Congenital heart defects in children]. PMID- 6912933 TI - [Treatment of children with kidney disease at local specialized sanatoria]. PMID- 6912934 TI - [Deontology in the nurse's work in a pediatric resuscitation department]. PMID- 6912935 TI - [Calendar ruler]. PMID- 6912936 TI - [Emergency states in adrenal pathology]. PMID- 6912937 TI - [New maternity hospital in Riga]. PMID- 6912938 TI - [Angina in children]. PMID- 6912939 TI - [Tics in children]. PMID- 6912940 TI - [Problems in the sex education of preschool children]. PMID- 6912941 TI - [Deontological problems in caring for older patients]. PMID- 6912942 TI - [Exudative diathesis]. PMID- 6912943 TI - [Changes in urine vitamin C, creatinine and uropepsin levels as a result of workload at standard work stations in the shipyard]. AB - In 30 randomly selected workers at standard shipyard work-stations, energetic expenditure was estimated by comparing the results with those of biochemical tests used for evaluating the workload degree, such as: creatinine and vitamin C content in urine, uropepsin activity, degree of saturating the organism with vitamin C. The same examinations were carried out in 20 auxiliary and administrative employees composing a control group. The results demonstrate decreased vitamin C level in urine and saliva towards the end of the working day in the productive" group (the one under examination) as compared to the control one." The total creatinine level and uropepsin activity were also enhanced in the urine of the productive workmen. The differences between the mean values between the examined and control groups were statistically significantly different. A correlation was found between the energetic expenditure and changes in the mentioned biochemical parameters in urine. PMID- 6912944 TI - Factors XI and XII and prekallikrein in sick and healthy premature infants. PMID- 6912945 TI - NATN workshop - the nursing process. PMID- 6912946 TI - Adenocarcinoma of the stomach presenting as multiple subcutaneous swellings. PMID- 6912947 TI - Management of operating departments in the reorganised health service - No. 4. PMID- 6912948 TI - Reorganisation and the theatre nurse manager - No. 3. PMID- 6912949 TI - Management of the operating department in the reorganised health service - No. 5. PMID- 6912950 TI - For and against equal access to health care. PMID- 6912951 TI - Corporate attitudes toward health care costs. PMID- 6912952 TI - Perspectives on the free choice of the source of personal health care. PMID- 6912953 TI - [Biological significance of the nephritic factor in membrano-proliferative glomerulonephritis]. PMID- 6912954 TI - Learning needs of the new graduate entering hospital nursing. PMID- 6912955 TI - Nurse-intern programs: how they're working. PMID- 6912956 TI - Textbook evaluation and selection in the curriculum. PMID- 6912958 TI - Self instruction: benefits and problems. PMID- 6912957 TI - She's not clumsy, she's left-handed. PMID- 6912959 TI - Law: dismissals for illness. PMID- 6912960 TI - Safe handling of cytotoxic drugs. PMID- 6912961 TI - Stress: the role of the OH nurse in prevention. PMID- 6912962 TI - Safety: the Fault Tree accident analysis. PMID- 6912963 TI - Yugoslavia: doubts on nuclear safety. PMID- 6912966 TI - [Relations with children with behavior disorders]. PMID- 6912968 TI - [Eating problems in patients with cerebral movement disorders]. PMID- 6912967 TI - [Dental prophylaxis. 1]. PMID- 6912965 TI - Job satisfaction from job safety. PMID- 6912969 TI - [Fear or information in the hospital. 2]. PMID- 6912970 TI - [Nursing profession - vocation or job?]. PMID- 6912964 TI - Who cares for the care-givers? PMID- 6912971 TI - Age-related burn injuries and their prevention. PMID- 6912972 TI - Update on dentistry for children. PMID- 6912973 TI - Nursing care of the lead-burdened child: a problem-oriented approach. PMID- 6912974 TI - A bed for infants with gastroesophageal reflux. PMID- 6912976 TI - Tradition--or transformation? PMID- 6912975 TI - Pediatric management problems: hyperkinesis. PMID- 6912977 TI - New direction. PMID- 6912978 TI - Chronobiology and health. PMID- 6912979 TI - The integrated curriculum from a developmental perspective. PMID- 6912980 TI - In quest of the perfect test. PMID- 6912981 TI - Measuring effects of a liberal education. PMID- 6912982 TI - Faculty role modeling. PMID- 6912983 TI - Health is not a right. PMID- 6912984 TI - Feminine attributes in a masculine world. PMID- 6912985 TI - Patient assessment-based on data, not intuition. PMID- 6912986 TI - Nursing economics. PMID- 6912987 TI - The measurement of uncertainty in illness. AB - The purpose of this investigation was to explore the role of uncertainty as a significant variable influencing patients' experiences in illness, treatment, and hospitalization. A theory was proposed on uncertainty in illness. Based upon this conceptualization, a 30-item scale tapping the uncertainty in symptomatology, diagnosis, treatment, relationship with care-givers, and planning for the future was developed. The Mishel Uncertainty in Illness Scale (MUIS) was factor analyzed and two factors were extracted from the data. Replication of the factor analysis provided support for the robustness of each factor. The reliability coefficient for each factor of the MUIS was highly adequate for both the initial and replication analyses. Three validation studies were conducted. Initial support for construct validity of the scale was demonstrated by the finding that the MUIS discriminates between treatment groups according to expected differences. Support for theoretical predictions was evidenced by the significant correlation between the MUIS and stress as measured by the Hospital Stress Events Scale. Convergent validity was supported by the finding that the MUIS correlates significantly with lack of comprehension. PMID- 6912988 TI - The Nurse Practitioner Rating Form. Part II: methodological development. PMID- 6912989 TI - Development of a tool for the measurement of maternal attachment during pregnancy. AB - A 24-item scale with five subscales was developed to measure the construct of maternal-fetal attachment during pregnancy and tested on 71 subjects in the third trimester of pregnancy. Content validity was built into the scale. A coefficient of reliability of .85 was demonstrated for the scale with the reliability of the subscales ranging from .52 to .73. Scores of the MFA scale were positively correlated with the amount of available social support reported by women and with their perceptions of babies three days after birth. There was a negative association between MFA scores and the amount of stress perceived by the women. Further refinement of the scale is indicated. PMID- 6912990 TI - Misconceptions and limitations of locus of control and the I-E scale. AB - Since 1966, locus of control as measured by the I-E scale has been shown predictive of many different dependent variables in both health and nonhealth situations. In hundreds of articles, expectancies have been reported to mediate perceptual, cognitive, and motivational processes. However, in many other investigations, locus of control has failed to predict the dependent variable being studied. Therefore, it is clear there are limitations to the predictive power of the construct. In recent years published research highlighting these limitations has resulted in a decrease in research about locus of control and the use of the I-E scale. Yet many investigators do not know or perhaps choose to ignore the criticisms published in recent years. Nurses who are interested in locus of control are encouraged to understand the construct and the frequent misapplications of it which occur, to realize the limitations of the I-E scale when considering instrumentation, and to consider multidimensional attribution theory as more appropriate to understanding behavior than locus of control. PMID- 6912991 TI - Health risk appraisal: process, problems, and prospects for nursing practice and research. AB - A number of methodological concerns and certain dimensions relevant to future development are generated in the above research: 1. The issue of test reactivity is especially critical in health risk appraisal instruments, since more advanced tools are designed to stimulate the recipient to take actions that might alter post-test results. Therefore, research studies using health risk appraisals need to control for the interaction effects of testing. Since health risk appraisals are reactive, the interaction of test effects with other experimental treatment (e.g. counseling) cannot be handled by use of non-reactive measures, as methodologists frequently suggest. 2. A second major threat to validity is the issue of experimental mortality. The clients who complete the health risk appraisal instrument are usually assumed to be self-motivated. Where engaged in large scale trials, however, their participation may be coerced at the outset but not enforced throughout the course of the study. Because of this some studies have a high proportion of dropouts. 3. Where this has not been the case, a third threat to validity, selectivity, is often a paramount concern, inasmuch as the populations who have subscribed to the instrument under their own motivation may be already pre-selected as very low risk individuals. In light of the paucity of controlled studies using health risk appraisals, it is difficult to draw conclusions regarding the state of the art. In summary, some general dimensions of the activity surround the development and use of health risk appraisals are: 1. The health risk appraisal appears to be more effective in motivating change with older rather than younger individuals. 2. Individuals given a health risk assessment within a supportive educational process do better than individuals exposed only to the results of a health risk appraisal. 3. Individuals given only a health risk appraisal and results without supportive education do better than individuals given no health risk appraisal. 4. Research participants and users of the instrument are, in almost every study, a self-selected group and appear to be healthier than the general population. One might question whether they are the more motivated population. PMID- 6912992 TI - Health risk appraisal: some methodologic considerations. AB - This is an outline of the structure and limitations of existing health risk appraisal tools (HRA). A general model is discussed, where average populations risk data are modified in a risk computation algorithm. This process requires information on risk relevant characteristics of the individual and rules or assumptions where sufficient data do not exist. The basis for risk estimation algorithms, the derivation of risk factors, and their combination into composites are described. HRA feedback to the individual user is discussed, including summarization of risk results in terms of risk age and life expectancy. PMID- 6912993 TI - The intraclass correlation as a measure of interrater reliability of subjective judgments. PMID- 6912995 TI - Wound care No. 1. PMID- 6912994 TI - Life events scaling: clinical methodological issues. PMID- 6912996 TI - Two community psychiatric nursing services compared. PMID- 6912997 TI - Statistical returns in community psychiatric nursing-2. PMID- 6912998 TI - What is negligence? PMID- 6912999 TI - Where's nurse? PMID- 6913000 TI - In the media: happy feelings. PMID- 6913002 TI - Nursing care study: mycoplasma pneumonia. PMID- 6913001 TI - Home treatment for children with haemophilia. PMID- 6913003 TI - Evolution of a system of nursing care in a small mixed unit. PMID- 6913004 TI - An ABC of nursing procedures. PMID- 6913005 TI - Nurses with drinking problems. PMID- 6913006 TI - Creating and working with small groups in a psychogeriatric hospital ward. PMID- 6913008 TI - Theatre nursing. PMID- 6913007 TI - Babies need BLISS. PMID- 6913009 TI - Theatre nursing: new techniques in orthopaedic surgery. PMID- 6913010 TI - Theatre nursing: middle third facial fractures. Part I: The fractures. PMID- 6913011 TI - Theatre nursing: middle third facial fractures. Part II: Fracture repair. PMID- 6913012 TI - Theatre nursing: teamwork and harmony. PMID- 6913014 TI - Theatre nursing: the air around us. PMID- 6913013 TI - Theatre nursing: cold cardioplegia. PMID- 6913015 TI - Theatre nursing: the job for me. PMID- 6913016 TI - Alive and studying in London E15! PMID- 6913017 TI - Mentally handicapped children: sensitivity is the watchword. PMID- 6913018 TI - Mentally handicapped children: the errors of our ways. PMID- 6913019 TI - Accountability in mental handicap hospitals: this deplorable state of affairs. PMID- 6913020 TI - Nodder report: winds of change. PMID- 6913021 TI - Student's forum - let's look at a problem: hiatus hernia. PMID- 6913022 TI - Verbal blunders and 'babytalk'. PMID- 6913023 TI - Reaching a key agreement. PMID- 6913024 TI - Epidemiology 1. The numbers's game. PMID- 6913025 TI - Sexual problems: time for talking. PMID- 6913026 TI - Compensation: when it's nobody's fault. PMID- 6913027 TI - The nursing process in midwifery: trial run. PMID- 6913028 TI - They never told me. PMID- 6913029 TI - Feldene: agent for many reasons. PMID- 6913030 TI - Myalgic encephalomyelitis: a baffling syndrome. PMID- 6913031 TI - Myalgic encephalomyelitis: faulty fibres? PMID- 6913032 TI - Orthopaedic traction: you're pulling my leg! PMID- 6913033 TI - Malignant hyperthermia: fighting a fatal fever. PMID- 6913034 TI - Nursing care study - astrocytoma: dignity, comfort and support. PMID- 6913035 TI - A pet may keep the doctor away. PMID- 6913036 TI - Now you're just a number. PMID- 6913037 TI - Epidemiology. 2 Patterns of disease. PMID- 6913038 TI - UK Central Council elections: why bother? PMID- 6913039 TI - Students' forum - let's look at a problem: food poisoning. PMID- 6913040 TI - Preventing hypertrophic scarring: a burning issue. PMID- 6913041 TI - Wading out of the backwaters. PMID- 6913042 TI - Possible hazards of working with cytotoxic agents: a review of the literature. PMID- 6913043 TI - Anaphylaxis resulting from chemotherapy. PMID- 6913044 TI - Clinical research and cancer nursing. PMID- 6913045 TI - A pilot investigation of home health care needs of cancer patients and their families. PMID- 6913046 TI - The impact of mastectomy on body image. PMID- 6913047 TI - Nurses' identification of patients as terminally ill. PMID- 6913048 TI - The Equal Rights Amendment and the Oncology Nursing Society. I. What is the Equal Rights Amendment? PMID- 6913049 TI - The Equal Rights Amendment and the Oncology Nursing Society. PMID- 6913050 TI - ERA and ONS: power from unity? PMID- 6913051 TI - Why the ONS has not taken a position regarding the Equal Rights Amendment. PMID- 6913052 TI - The Equal Rights Amendment and the Oncology Nursing Society. IV. Avenues for action. PMID- 6913053 TI - A patient teaching aid for the pelvic exenteration patient. PMID- 6913054 TI - Effect of vanadate on pharmacological actions of cardiac glucosides. PMID- 6913055 TI - Update on digestive diseases. PMID- 6913056 TI - The differential diagnosis of jaundice. PMID- 6913058 TI - When the recruiter gets recruited: a professional analogy. PMID- 6913057 TI - An approach to recurrent abdominal pain in children. PMID- 6913059 TI - Increasing retention through awareness of professional needs. PMID- 6913060 TI - Now that you've selected your agency, where do you begin? PMID- 6913061 TI - Why a nurse recruitment program? PMID- 6913062 TI - [Proposal of a philosophy for nursing in a university hospital]. PMID- 6913063 TI - [Nursing functions in epidemiologic surveillance]. PMID- 6913064 TI - [Support as a therapeutic measure in nurse-patient relations]. PMID- 6913065 TI - [Nursing care in antimicrobial therapy]. PMID- 6913066 TI - [Are we going to write to publish? (A teaching strategy)]. PMID- 6913067 TI - [Nursing notes]. PMID- 6913068 TI - [Integration of the pediatric nursing discipline in the graduating course curriculum of the University of Sao Paulo Nursing School]. PMID- 6913069 TI - [Nursing assistance to patients with mental confusion]. PMID- 6913070 TI - [Research tools and technics in psychiatric nursing. III. The relationship of nursing personnel attitudes and a test of the perception of their function]. PMID- 6913071 TI - [Teaching of community nursing in Sao Paulo]. PMID- 6913072 TI - [Nursing process: its implications in education and service]. PMID- 6913073 TI - [Program for training in resuscitation of cardiopulmonary arrest]. PMID- 6913074 TI - [Rehabilitation of the ostomy patient]. PMID- 6913075 TI - [Considerations and nursing routines used in radium-molding]. PMID- 6913076 TI - [Occupational accidents in hospitals]. PMID- 6913077 TI - [Experience in the use of a birdseed mattress in the prevention of decubitus ulcer]. PMID- 6913078 TI - [Manifestation of behavior by mental patients not tolerated by the nursing staff]. PMID- 6913079 TI - [Crede's methods: regulation and technic]. PMID- 6913080 TI - [Tentative course in obtaining a vaccine for the prevention of hepatitis B]. PMID- 6913081 TI - [Nursing organizations]. PMID- 6913082 TI - Sex Q & A: frank answers to your most delicate patient-counseling questions. PMID- 6913083 TI - Battered women: the ways you can help. PMID- 6913084 TI - One hospital's very workable approach to battering. PMID- 6913085 TI - Ileal conduit surgery: how to help a terrified patient. PMID- 6913086 TI - What all those pressure readings mean...and why. PMID- 6913087 TI - Looking for a job? Be picky about your benefits. PMID- 6913088 TI - Tattletale lesions: a warning in disguise. PMID- 6913089 TI - Step by step through an arterial stick. PMID- 6913090 TI - Is digitalis the solution or cause of this problem? PMID- 6913091 TI - Toward impeccable IV technique: IV bolus leaves no room for error. PMID- 6913092 TI - The fine art of giving a physical: how to coax out a frank patient history. PMID- 6913093 TI - They spared my daughter a lifetime of guilt. PMID- 6913094 TI - Keep this quick flow-rate calculator handy and hold onto this glossary of IV fluid terms, too. PMID- 6913095 TI - Legally speaking: when pulling the plug spells murder. PMID- 6913096 TI - Sound off! 'Oremization,' the curse of nursing. PMID- 6913097 TI - Leadership at work: how to write a teaching aid that patients will actually read. PMID- 6913098 TI - Leadership at work: how to polish up a tarnished image. PMID- 6913099 TI - Sex Q & A: frank answers to your most delicate patient counseling questions. PMID- 6913100 TI - Infection consult: tips and tactics to hold microbes at bay, for your patient's - and your own. PMID- 6913101 TI - Booby-trapped orders. PMID- 6913102 TI - Add paradoxical pulse to your assessment routine. PMID- 6913103 TI - When moments count... the two eye emergencies that demand instant intervention. PMID- 6913104 TI - Opinion exchange: is this hospital's 'gag rule' right? PMID- 6913105 TI - The fine art of giving a physical: organizing your plan of action. PMID- 6913106 TI - Dysrhythmia of the month club: which strip means the most trouble? PMID- 6913107 TI - Are you ready for a total pancreatectomy patient? PMID- 6913108 TI - Toward impeccable IV technique: how to make infusion control devices work for you (instead of vice versa). PMID- 6913109 TI - Neurodiagnostic studies: pre-and post-procedure care. PMID- 6913110 TI - What to watch for with digitalis. PMID- 6913111 TI - Late bloomer. PMID- 6913112 TI - Legally speaking: to avoid a lawsuit, keep the record straight. PMID- 6913113 TI - Sound off! Should a 'no code' be a death sentence? PMID- 6913114 TI - Theory to practice. Interview by Kay Harrison. PMID- 6913115 TI - Nursing leadership: where is it? PMID- 6913116 TI - [Tumors of the upper urinary tract]. PMID- 6913117 TI - [Haunted by cancer]. PMID- 6913118 TI - [Additional tests in the diagnosis of kidney tumors]. PMID- 6913119 TI - [Radiologic tests of kidney tumors: technic, indications, results]. PMID- 6913120 TI - [Fortal]. PMID- 6913121 TI - [A malignant tumor in children: nephroblastoma]. PMID- 6913122 TI - [Health of man and groups and nursing education]. PMID- 6913123 TI - [New regulations governing the nursing profession]. PMID- 6913124 TI - [Cystic tumors of the kidney]. PMID- 6913125 TI - [Amebic colitis]. PMID- 6913126 TI - [Other visceral localizations of amebiasis]. PMID- 6913127 TI - [A disease due to bad hygiene]. PMID- 6913128 TI - [Management of parasitologic diagnosis]. PMID- 6913129 TI - [Treatment of amebiasis]. PMID- 6913130 TI - [Case report of acute intestinal amebiasis]. PMID- 6913131 TI - [Amebiasis: epidemiology, physiopathology and anatomopathology]. PMID- 6913132 TI - [Health needs in Martinique]. PMID- 6913133 TI - [Ambulatory hospital team - a challenge for team work and new thinking]. PMID- 6913135 TI - [National meeting business 1981: nomination of committee for long term planning]. PMID- 6913134 TI - [Need for geriatric nurses]. PMID- 6913136 TI - [Norwegian Nurses' Association's organizational development]. PMID- 6913137 TI - [Organizational structures in the hospital sectors: Norwegian Nurses' Association's comments on the Hospital Organization Committee report]. PMID- 6913138 TI - [Year of the Handicapped: Voksentoppen--what is it?]. PMID- 6913139 TI - [Occupational health nurses' discussion: nursing schools and occupational health services]. PMID- 6913140 TI - [From the conference on cancer nursing: a life with cancer. A patient speaks]. PMID- 6913141 TI - [Counseling service for homosexuals]. PMID- 6913142 TI - [Deaconesses versus Florence Nightingale]. PMID- 6913143 TI - [Alternative proposal for psychiatric hospitals. Impressions from a study tour to Rome]. PMID- 6913144 TI - [ILO symposium on education in working environment]. PMID- 6913145 TI - [It is not enough to be kind!]. PMID- 6913146 TI - [Health activities in Nepal]. PMID- 6913147 TI - [Psychiatric nursing and qualitative intelligence]. PMID- 6913148 TI - [Aphasia]. PMID- 6913149 TI - [Nursing assistants' education in more advanced schools]. PMID- 6913150 TI - [Nurses and medical secretaries in primary health services]. PMID- 6913151 TI - [Working environment and trial of change. Experiences from a somatic hospital and a nursing home/convalescent home]. PMID- 6913152 TI - [Future nursing - in Africa and Europe]. PMID- 6913153 TI - [The concept profession - a dilemma in Norwegian nursing?]. PMID- 6913154 TI - [That's the way it is in Kirken's hospital]. PMID- 6913155 TI - [Perspectives in nursing and health care research]. PMID- 6913157 TI - [Psychiatric nurses in primary health services]. PMID- 6913156 TI - [Impressions from a study tour to Leningrad]. PMID- 6913158 TI - [College system and the new nursing education]. PMID- 6913159 TI - [Student comments: nursing education and Long-range committee recommendations]. PMID- 6913160 TI - [Nursing research in practice. An example from Innherred Hospital]. PMID- 6913161 TI - [Patient environment in health facilities]. PMID- 6913162 TI - [Executive Board meeting 6-7 April 1981: prognosis points to deprofessionalization of the primary care sector]. PMID- 6913163 TI - [Appeal from the Danish Nursing Council's executive board to the government: government should demand communities to increase the number of education positions]. PMID- 6913164 TI - [The 4th annual meeting of representatives: important to formulate joint goals for health care and nursing]. PMID- 6913165 TI - [Now we investigate to find out which of these we are]. PMID- 6913166 TI - [New direction in the campaign against unemployment: crisis will struggle both on the national and on the European plan]. PMID- 6913167 TI - [Health Administration, Communities' National League and Danish Nursing Council agree: home care nurses have no duty to relieve nursing home managers]. PMID- 6913168 TI - [Comments on the interview with Eli Magnussen: the high standards of basic education deserve to remain for the time being]. PMID- 6913169 TI - [FTF conference on social economy and the growing employment problem: nightmare for millions in West Europe]. PMID- 6913170 TI - [British labor union leader warns against following Thatcher's government example: every day 2500 lose their job]. PMID- 6913171 TI - [Internationally coordinated flight against unemployment]. PMID- 6913172 TI - [Problem solving in nursing care merely at the beginning stage]. PMID- 6913174 TI - [Drug information: general aspects of blood coagulation]. PMID- 6913173 TI - [What purpose does it serve?]. PMID- 6913176 TI - [Executive Board meeting 12-13 May 1981: contract with WHO for research-oriented expert assistance to the DISS]. PMID- 6913175 TI - [Opening of the Danish Institute for Health Care and Nursing Research (Diss): nurses have a considerable role to play in health research]. PMID- 6913177 TI - [Assessment-/treatment-/nursing progress in the hospital: what is involved in the most frequently occurring diseases?]. PMID- 6913178 TI - [Comments on "Nursing process; abstract concept or working tool" in No. 4/81: care planning and not nursing process is the working tool]. PMID- 6913179 TI - [Danish Hospital Institute on the currently observed health threshold limit values for anesthetic gases: safety conditions satisfactory if thresholds are observed]. PMID- 6913180 TI - [Community health nurse at work in England: priority setting of visits to children at risk according to a point system]. PMID- 6913182 TI - [Large words and costly meaning]. PMID- 6913181 TI - [Director of WHO Europe Regional Nursing Department retires: do unto others what you want others to do unto you. Interview by Inger Rosenkvist]. PMID- 6913183 TI - [Offer of drugs which have not been tested at all]. PMID- 6913184 TI - [New security institution in the county hospital in Nykobing Sjaelland]. PMID- 6913185 TI - [Early caries in the deciduous teeth of infants and young children: acute caries in children can be avoided by better parent education]. PMID- 6913186 TI - [Seminar in Lillehammer on the needs of sick children: for children in crisis the parents are the natural authority]. PMID- 6913187 TI - [Drug information: coagulation inhibiting agents. II. Indirectly-acting anticoagulants. Coumarin derivatives: dicumarol, phenprocoumon (Marcoumar), warfarin (Marevan). Indandione derivatives: phenindione (Dindevan)]. PMID- 6913188 TI - [From medicine order book via ADP to requisitions]. PMID- 6913189 TI - [Drug misuse or insufficient prescription procedure: can one-third of the patients use drugs correctly?]. PMID- 6913190 TI - [Choice of aids for the home control of blood sugar: can quickly cost the patient a lot of money]. PMID- 6913191 TI - [Epidural morphine provides optimal analgesia]. PMID- 6913192 TI - [Health administration on home health nurses' assistance in: pain treatment via epidural catheter]. PMID- 6913193 TI - [Home care nurse teaches the use of epidural morphine]. PMID- 6913194 TI - [Practical guidelines can lead to great risk]. PMID- 6913195 TI - [Who manages the hospital sector?]. PMID- 6913196 TI - [Annual end-of-term celebrations in Denmark's nursing colleges in Copenhagen and Arhus: remember that you don't own the patient]. PMID- 6913197 TI - [Study tour to the Soviet Union: continuous evaluation instead of an actual examination]. PMID- 6913198 TI - [Evaluation of the consequences of precise technology: technology evaluation must also include the activity plan]. PMID- 6913199 TI - [Resource control within the hospital system: not an accounting technological but an organizational problem]. PMID- 6913200 TI - [Executive Board meeting, 9-10 June 1981: larger scholarships for study can benefit the nursing profession]. PMID- 6913201 TI - [Drug information: coagulation inhibiting drugs. III, Thrombocyte function inhibiting drugs]. PMID- 6913202 TI - [It looks like an offer but it is a misrepresentation]. PMID- 6913203 TI - [More than half of all primiparas are against offer]. PMID- 6913204 TI - [Nurse on psychotherapeutic treatment of cancer patients: sound evidence that psychotherapy can be an active factor]. PMID- 6913205 TI - [Psychologist on psychological treatment of cancer patients: rich possibilities for therapeutic support of patients with cancer]. PMID- 6913206 TI - [Security institution in Nykobing Sjaelland: the closed environment offers possibilities for the best observations]. PMID- 6913207 TI - [Exciting reading save for the orthodox]. PMID- 6913208 TI - [WHO at World Health Day: WHO's future strategy has an effect on the national legislation]. PMID- 6913210 TI - [Accident statistics for social service and health service system: a necessity with an improved description of the accident conditions]. PMID- 6913209 TI - [American nursing - myths, motives and reviews. 2. The largest hospital of its kind with 4000 children under treatment]. PMID- 6913211 TI - [Drug information: antiparkinson agents]. PMID- 6913212 TI - [Why undermine a good offer and create problems?]. PMID- 6913213 TI - [American nursing - myths, motives and reviews. 3. Hard to compare Danish and American nursing education]. PMID- 6913214 TI - [Risk program in Randers community: proposal for children whose development present special problems]. PMID- 6913215 TI - [Hopes that UN funds might be used for a center for torture victims]. PMID- 6913216 TI - [Infant prophylaxis in Denmark. 4. Health visitor can often decide herself what is meant with need]. PMID- 6913217 TI - [The wise virgin]. PMID- 6913218 TI - [Executive Board meeting 11-12 August 1981: striking difficulties about extension of educational capacities]. PMID- 6913219 TI - [Infant prophylaxis in Denmark. 5. Need to discuss termination or continuation of visits to the home]. PMID- 6913220 TI - [Statement from the Health Administration in relation to the younger physicians' strike, May 1981: Health Administration's tasks and actions during physicians' conflict]. PMID- 6913221 TI - [Acute observation of patients with head trauma]. PMID- 6913222 TI - [Drug information: antiparkinson agents. I. Anticholinergic agents]. PMID- 6913223 TI - [Danish-Saudi Arabian health project in Jizan: Denmark assists with the operation of a new 475-bed hospital]. PMID- 6913224 TI - [Literature searching and use of libraries: a condition for moving along with professional development]. PMID- 6913225 TI - [Evaluation model used in management plans: evaluation which can release resources for nursing management]. PMID- 6913226 TI - [Infant prophylaxis in Denmark, 7. What good do preventive efforts really do?]. PMID- 6913227 TI - [Information from Health Administration: nurse penalized with a fine for inadequate care]. PMID- 6913228 TI - [Head nurse Tove Geisler, Finsen Institute: oncological nursing is different on account of its complexity. Interview by Inger Rosenkvist]. PMID- 6913229 TI - [Appeal to Danish nurses: help patients and colleagues in crises-wracked Poland]. PMID- 6913230 TI - [How dangerous are cytostatic agents?]. PMID- 6913231 TI - [AFK's report: Health sectors - resources and productions since 1965: exciting for everyone who follows developments in the health sectors]. PMID- 6913232 TI - [From team nursing to total care and primary nursing: total care can pave the way for primary nursing]. PMID- 6913233 TI - [Analysis of the 1954-generation: yesterday was best for men]. PMID- 6913234 TI - [Distribution of expenses will increase counties' educational capacity]. PMID- 6913235 TI - [Involvement of relatives in the care of the seriously ill patient: we should show that we have a use for the relatives in the daily care]. PMID- 6913236 TI - [To be fed - a crisis experience: patients should have confidence in themselves and in that of the food-giver]. PMID- 6913237 TI - [Drug information: antiparkinson agents. II. Dopaminergic agents]. PMID- 6913239 TI - [Report from VBL's (Health and Child Care Teachers) study days in Sundsvall. "Active evaluation"]. PMID- 6913238 TI - [Effect of hyperbaric oxygenation on the activities of the sympathetic-adrenal system and the blood kallikrein-kinin system in acute arrhythmia]. PMID- 6913240 TI - [Theories about comprehensive care]. PMID- 6913241 TI - [Children and stress]. PMID- 6913242 TI - [Terminal care]. PMID- 6913243 TI - [Research activities in clinical instructors' functions]. PMID- 6913244 TI - [They help students to "reach out" to patients]. PMID- 6913245 TI - [Comprehensive care of the dying patient and his family]. PMID- 6913246 TI - [Wife abuse - a handicap]. PMID- 6913247 TI - [Visit to the women's home in Goteborg]. PMID- 6913248 TI - [Various observations on speech prohibition]. PMID- 6913249 TI - [Report from the Home Care Congress]. PMID- 6913250 TI - [A model for research connection with education in the Red Cross school of nursing]. PMID- 6913251 TI - [Various impressions from a study tour to Bergen]. PMID- 6913252 TI - [What nursing instructors teach in consumer planning and social service planning]. PMID- 6913254 TI - [The practice of medical disciplinary law]. PMID- 6913253 TI - [Transfer problem and adaptation problems in geriatric care]. PMID- 6913255 TI - [The hard-to-measure advantages of a health center. Satisfied patients in Nieuw Waldeck]. PMID- 6913256 TI - [Folk medicine in the Netherlands. IV]. PMID- 6913257 TI - [The occurrence and prevention of hepatitis B]. PMID- 6913258 TI - [Leave the person his own dignity]. PMID- 6913259 TI - [The first 40 weeks of our life]. PMID- 6913261 TI - [Folk medicine in the Netherlands. VI]. PMID- 6913260 TI - [The importance of friends for the elderly person]. PMID- 6913262 TI - [Sage: Salvia officinalis from the mint family]. PMID- 6913263 TI - [Epidural anesthesia as analgesia during childbirth]. PMID- 6913264 TI - [Potassium and the older person]. PMID- 6913265 TI - [Nursing care in chemotherapy. Developments and current possibilities of chemotherapy]. PMID- 6913266 TI - [Nursing care in adverse effects of chemotherapy]. PMID- 6913267 TI - [Information; especially for patients treated with cytostatic agents]. PMID- 6913268 TI - [This is how patients can feel... Nursing care in chemotherapy]. PMID- 6913269 TI - [Acceptance of cancer by society. Nursing care in chemotherapy]. PMID- 6913270 TI - [Nursing care for outpatients on chemotherapy]. PMID- 6913271 TI - [Patient-nurse relationship]. PMID- 6913272 TI - Liking yourself. Nursing care in chemotherapy. PMID- 6913273 TI - [Various aspects of cancer nursing in the Netherlands]. PMID- 6913274 TI - [Possibilities of nursing instructor education for former graduates of the H.B.O.V. (Higher Professional Education in Nursing)]. PMID- 6913275 TI - [Introduction to the theory of personnel staffing on a nursing department]. PMID- 6913276 TI - [Patient-oriented care - starting-point for development of nursing competence. II]. PMID- 6913277 TI - [A patient with a muscular disease! What can we still do?]. PMID- 6913278 TI - [Revision of nursing education legislation]. PMID- 6913279 TI - [Nursing care of clients in an abortion clinic]. PMID- 6913280 TI - [Currently used methods in induced abortion]. PMID- 6913281 TI - [Induced abortion in the hospital - the role of nursing]. PMID- 6913282 TI - [Readers' position against induced abortion]. PMID- 6913283 TI - [Current viewpoint of nursing - repercussion on practice and education]. PMID- 6913284 TI - [Authorization: a pacifier]. PMID- 6913285 TI - [Patients with epilepsy. A seizure is more than one neurological fact]. PMID- 6913286 TI - [What is epilepsy and how is it treated?]. PMID- 6913287 TI - [Nursing aspects in the care of epilepsy patients]. PMID- 6913288 TI - [Patients with epilepsy. Who is the patient and how is the education?]. PMID- 6913289 TI - [Problems and desires of people with epilepsy and the attitude of the public]. PMID- 6913291 TI - Reorganizing an operating room. PMID- 6913290 TI - [Drug information. Once upon a time there was a drug addict... nonsense or future?]. PMID- 6913292 TI - CNOR: the southern way. PMID- 6913294 TI - Friendly communication by the dog. PMID- 6913293 TI - Hepatic function test--1: hepatic enzymology. PMID- 6913295 TI - It came out of the sky. PMID- 6913296 TI - Complete uterine prolapse in a mare. PMID- 6913297 TI - Hyperthermia for the treatment of dermatomycosis in dogs and cats. PMID- 6913298 TI - Surgical treatment of canine perianal fistulas. PMID- 6913299 TI - Cryotherapy performed on perianal fistulas in dogs. (Washington State University 1976--1980). PMID- 6913300 TI - Ruptured urethra caused by trauma in a dog. PMID- 6913301 TI - A metastatic pheochromocytoma causing progressive paraparesis in a dog. PMID- 6913302 TI - Safe management and prevention of gastric distention volvulus in dogs. PMID- 6913303 TI - Preliminary studies on the effect of praziquantel against tapeworms in dogs and cats. PMID- 6913304 TI - Summary of safety evaluations for praziquantel in dogs. PMID- 6913305 TI - Dirofilariasis in a captive wolf pack. PMID- 6913306 TI - Surgical repair of bovine persistent penile frenulum. PMID- 6913307 TI - Malignant theca-granulosa cell tumor in a heifer. PMID- 6913308 TI - Diagnosis of mastitis in goats. PMID- 6913309 TI - A comparison of four short-acting anesthetic combinations for swine. PMID- 6913310 TI - Otitis media in a thoroughbred. PMID- 6913311 TI - Acute onset of degenerate joint disease in the stifle of a mare. PMID- 6913312 TI - Anhidrosis in a thoroughbred. PMID- 6913313 TI - Diaphragmatic hernia in the horse. PMID- 6913314 TI - A technique for repairing fractures in birds. PMID- 6913315 TI - Ethical legal update: malpractice--a suit in your future! PMID- 6913316 TI - Caesarean childbirth: variables affecting psychological impact. PMID- 6913317 TI - Behavioral adaptation during the acute phase of a myocardial infarction. PMID- 6913318 TI - Conceptual system, students, practitioners. PMID- 6913319 TI - Assessment scales for determining the cognitive--behavioral repertoire of the obese subject. PMID- 6913320 TI - Human subjects protection in hospital field studies. PMID- 6913321 TI - Ethical issues in nursing research. PMID- 6913322 TI - Strategies for teaching nursing research: experiential learning in data collection. PMID- 6913323 TI - Problems in doing nursing research: measurement error and attenuation. PMID- 6913324 TI - [Ward supervisor without qualifications gets position in intensive care]. PMID- 6913325 TI - [The profession has a job with members' problems]. PMID- 6913327 TI - [Nurses in Jorn get no holidays]. PMID- 6913326 TI - [Karin Arhland, new Minister of Health Services: no, to making health care private. Interview by Jan Thomasson]. PMID- 6913328 TI - [An annual congress for the established men who control our county council]. PMID- 6913329 TI - [Schedule change made it possible: trial of team nursing in Mora]. PMID- 6913330 TI - [Lars invents a recording system which everybody likes. Interview by Viveka Holmertz]. PMID- 6913331 TI - [This is what the members are to the profession. Interview by Viveka Holmertz]. PMID- 6913332 TI - [Child health services get a misleading description]. PMID- 6913333 TI - [Do child health centers answer the need found in society?]. PMID- 6913335 TI - [Swedish national labor union should take a more active part in solidarity activity. Interview by Jan Thomasson]. PMID- 6913334 TI - [Conflict evaluation shows: it is right to strike]. PMID- 6913336 TI - [New Zealand: child care paid by companies and privately]. PMID- 6913337 TI - [Increased information decreases anxiety in ECG-examinations]. PMID- 6913338 TI - [District health nurse will have more time for preventive care]. PMID- 6913339 TI - [Think carefully before accepting a job in developing countries]. PMID- 6913340 TI - [Gulshanara--home visitor and vaccination recruiter]. PMID- 6913341 TI - [Health care research. Practical experience is the most important for the solving of health care problems]. PMID- 6913342 TI - [Leaking equipment exchanged]. PMID- 6913343 TI - [Researchers and personnel in Nacka together change work routine]. PMID- 6913344 TI - [Laughing or crying?]. PMID- 6913345 TI - [ICN congress: discussion in small groups an appreciated feature]. PMID- 6913346 TI - [Kirsten Stallknecht, newly-elected board member: wage and employment conditions important questions for ICN. Interview by Karin Olsson]. PMID- 6913347 TI - [Authorization for all SHSTF-members?]. PMID- 6913348 TI - [Indian reservation in USA needs its own nurses. Interview by Ingrid Engstedt and Peter Williams]. PMID- 6913349 TI - [Current neurohumoral and therapeutic aspects of hypertension]. PMID- 6913350 TI - Discharge dilemma for an ED nurse. PMID- 6913351 TI - Nursing diagnosis in cancer chemotherapy--in theory and in practice. PMID- 6913352 TI - Monitoring blood glucose at home: who should do it and how? PMID- 6913354 TI - Dealing with feelings: worry journal and guilty time. PMID- 6913353 TI - Monitoring blood glucose at home: a comparison of three products. PMID- 6913355 TI - Air embolism and central venous lines. PMID- 6913356 TI - The unspoken needs of families during high-risk pregnancies. PMID- 6913357 TI - Pregnancy after reproductive failure. PMID- 6913359 TI - Reality shock in reverse. PMID- 6913358 TI - Nursing on an island. PMID- 6913360 TI - Hirschsprung's disease. PMID- 6913361 TI - The worst of times or the best? PMID- 6913362 TI - Drug data: penicillins--the fifth generation. PMID- 6913363 TI - Dilemmas in practice: whom can you tell? PMID- 6913364 TI - Determining learning needs for OR staff. PMID- 6913365 TI - Effects of patching on sterilization of surgical textiles. PMID- 6913366 TI - Proposed recommended practices for OR sanitation. PMID- 6913367 TI - Interpreting normal electrocardiograms. PMID- 6913368 TI - Legal considerations for nurse researchers. PMID- 6913369 TI - Surgical suite is no place for jewelry, watches, or nail polish. PMID- 6913371 TI - Blood loss determination. PMID- 6913370 TI - Hospital insurance unlikely to cover moonlighting nurses. PMID- 6913372 TI - Let's take the bedpan out of the public's image of nursing. PMID- 6913373 TI - Independence or the transfer of control. PMID- 6913374 TI - When the abused child comes to surgery. PMID- 6913375 TI - Developing empathy. Child abuse: fallout in adulthood. PMID- 6913376 TI - Skills for helping others to redirect emotional response. PMID- 6913377 TI - Epidemic infections in surgical patients. PMID- 6913378 TI - What's behind the dramatic increase in hospital costs? PMID- 6913379 TI - Midtrimester abortion patients. PMID- 6913380 TI - Nurses in Denver adopt self-governance. PMID- 6913381 TI - Neurogenic bladder incontinence: the consequences of mismanagement. PMID- 6913382 TI - The role of the nurse clinician in a rehabilitation outpatient setting. PMID- 6913383 TI - Legislation scene. PMID- 6913384 TI - Natural death legislation. PMID- 6913386 TI - Degree programs for nurses in Britain. PMID- 6913385 TI - The nurse and the law: a macabre landmark case. PMID- 6913387 TI - Drugs in current use: frusemide. PMID- 6913388 TI - Stress and the adolescent nurse. PMID- 6913389 TI - Teaching through research: stress and the hospitalized adolescent. PMID- 6913390 TI - Poland: a nursing overview. PMID- 6913391 TI - Social implications of blindness. PMID- 6913392 TI - Nursing students' perceptions of teaching in the clinical area. PMID- 6913393 TI - The role of the dialysis nurse. PMID- 6913394 TI - The first hundred weeks--part II. PMID- 6913395 TI - [Information services and the health professions]. PMID- 6913396 TI - [Authorization regulations and the law]. PMID- 6913398 TI - [Discipline, a collective viewpoint...]. PMID- 6913397 TI - [Continued education. The importance of postoperative care]. PMID- 6913399 TI - [Prospects and future perspective in Quebec]. PMID- 6913400 TI - [Continued education. The importance of postoperative care]. PMID- 6913401 TI - [Authorization regulation and the law]. PMID- 6913402 TI - [Mesdames Francoise Savard and Claire Boisvert, 2 devoted and generous professors. Interview by Marie-Estelle Primavesi]. PMID- 6913403 TI - [Rejean Cayer, a nursing assistant out of the ordinary. Interview by Marie Estelle Primavesi]. PMID- 6913404 TI - [Continued education. Application of heat and cold by compresses, bags and baths]. PMID- 6913405 TI - [1981 seminar: the patient. The needs and the rights of patients]. PMID- 6913406 TI - Identification of a histidine residue near the aminoacyl transfer ribonucleic acid binding site of elongation factor Tu. AB - The complex of elongation factor Tu with GTP (EF-Tu.GTP) reacts with N or epsilon -bromoacetyl-lys-tRNA ( or epsilon BrAcLys-tRNA) to form a functional covalently linked complex (XLTC). The site of cross-linking must be near the site on EF Tu.GTP that binds the aminoacyl moiety of aminoacyl transfer ribonucleic acid (AA tRNA). For identification of this site, a nanomole of purified XLTC prepared from or epsilon BrAc[(14)C]Lys-tRNA was digested first with RNase A and then with trypsin, and the peptides were resolved by high-performance liquid chromatography using a c8 reverse-phase column. A single peptide contained 80% of the label. The amino acid composition of this peptide was identical with that of residues 59-74 in EF-Tu. The NH2-terminal sequence of the peptide was determined to be Fly-Ile Thr-Ile, which are residues 59-62 in EF-Tu. The modified amino acid was identified as pi - (carboxymethyl)histidine, which establishes that His-66 is at or near the AA-tRNA binding site on EF-Tu.GTP. PMID- 6913407 TI - The relationship between the transport of glucose and cations across cell membranes in isolated tissues. XI. The effect of vanadate on 45Ca-efflux and sugar transport in adipose tissue and skeletal muscle. AB - (1) The effects of vanadate of hexose transport, 45Ca-exchange and (Na+, K+) contents have been characterized in isolated adipose tissue and skeletal muscles of the rat. (2) In whole epididymal fat pads, vanadate (0.5-5.0 mM) markedly stimulated the uptake of 2-deoxy[14C]glucose as well as the efflux of 3-O [14C]methylglucose. (3) Within the same concentration range, vanadate induced an early increase in 45Ca-washout from preloaded fat pads. The maximum increases in the fractional losses of 3-O-[14C]methylglucose and 45Ca were significantly correlated (P less than 0.001, r = 0.98). (4) In extensor digitorum longus and soleus muscles, vanadate (0.5-5.0 mM) stimulated the efflux of 3-O [14C]methylglucose and this effect was preceded by rise in the washout of 45Ca. The maximum increases in the fractional losses pf 3-O-[14C]methylglucose and 45Ca were significantly correlated (P less than 0.005, r = 0.98). (5) In extensor digitorum longus and soleus muscles, vanadate increased K+-contents and decreased Na+ contents. (6) The stimulation of 45Ca-washout presumably reflects an increase in the cytoplasmic Ca2+ level, brought about by an inhibitory effect of vanadate on the Ca2+-sensitive ATPase of the sarcoplasmic or the endoplasmic reticulum. As demonstrated for most other insulin-like agents (Sorensen, S.S., Christensen, F. and Clausen, T. (1980) Biochim. Biophys. Acta 602, 433-445), the stimulating effect of vanadate on glucose transport appears to be associated with or mediated by a rise in the cytoplasmic Ca2+ level. PMID- 6913408 TI - The effects of leucocyte elastase on the mechanical properties of adult human articular cartilage in tension. AB - The effects of leucocyte elastase on the tensile properties of adult human articular cartilage were examined in detail in 99 specimens from hip, knee and ankle joints in the age range 16-83 years. The results showed that elastase reduced the tensile stiffness of cartilage, both at low stress and at fracture. The tensile strength of cartilage was also considerably reduced by the action of elastase. Biochemical analysis of the incubation media, and the specimens, revealed that 90%, or more, of the proteoglycan was released from the cartilage, whilst the release of collagen was negligible. Leucocyte elastase is known to degrade the non-helical terminal peptides of cartilage collagen molecules and thereby disrupt the main intermolecular cross-links in collagen fibrils. A previous study (Kempson, G.E., Tuke, M.A., Dingle, J.T., Barrett, A.J. and Horsfield, P.H. (1976) Biochim. Biophys. Acta 428, 741-760) showed the lack of effect of proteoglycan degradation alone on the tensile strength and stiffness of cartilage. The reduction in strength and stiffness recorded in the present study can, therefore, be attributed to the action of elastase on the collagen in cartilage and it emphasises the important of covalent intermolecular cross-links to the mechanical properties of collagen fibrils. PMID- 6913409 TI - Measurement of urinary kallikrein activity. Species differences in kinin production. AB - A sensitive, specific radioimmunoassay for kinins has been developed, which is able to detect 1.5 pg bradykinin or 3 pg lysyl-bradykinin (Lys-bradykinin). 50% displacement in the standard curve was obtained with 10 pg bradykinin or 15 pg Lys-bradykinin in 0.6-ml incubates. The antisera, raised against bradykinin, recognized well Lys-bradykinin and methionyl-lysyl-bradykinin (Met-lys Bradykinin), but cross-reacted 0.4% or less with bradykinin fragments. Kininogen cross-reacted only 0.2%. The radioimmunoassay and kininogen from several species were used in the measurement of human and rat urinary kallikrein activity. The peptide generated by hydrolysis of the substrates by rat or human urines was characterized by radioimmunoassay in two different systems: polyacrylamide gel electrophoresis and carboxymethyl cellulose chromatography. Both urines did not produce the same kinin: the kinin produced by human urine migrated like Lys bradykinin, whereas the kinin produced by rat urine migrated like bradykinin. This gives evidence of differences in the specificity between kinin-forming enzymes in rat and human urines. PMID- 6913410 TI - Immunologic abnormalities in myelofibrosis with activation of the complement system. AB - Eighteen patients with agnogenic myeloid metaplasia with myelofibrosis were studied for clinical and laboratory evidence of immunologic dysfunction. Clinical findings included the presence of arthritis, vasculitis, and erythema nodosum. Laboratory abnormalities included the presence of circulating immune complexes, antinuclear antibodies, positive direct Coombs tests, elevated latex fixations, and a circulating lupus type anticoagulant. Total hemolytic complement was markedly depressed in four patients. Analysis of complement (C) components C1-C9 and factor B demonstrated significant reduction of only C3 and factor B. By crossed-immunoelectrophoresis, both C3 and factor B, but not C4, were cleaved, indicating that C activation was occurring predominantly via the alternative pathway. The control proteins beta 1H and C3b inactivator were decreased in three of four patients with hypocomplementemia. These data suggest that immunologic mechanisms associated with activation of the complement system play an important role in the disease process of some patients with agnogenic myeloid metaplasia with myelofibrosis. PMID- 6913411 TI - Relative risk of adolescent drug abuse: Part I. Socio-demographic and interpersonal variables. AB - This study was carried out on a sample of 254 male senior high school students in New Delhi. The authors found that variables contributing significantly to drug use were age, heterosexual dating, drug abuse among family members and drug abuse among friends. However, drug use was not found to be significantly associated with family income, father's occupation, family structure and place of residence. Since the sample studied was relatively small, additional confirmation is needed. PMID- 6913412 TI - Transplantation, identity and drug addiction. AB - This report is the follow-up of an earlier work in which the authors set forth some considerations on the psychopathological aspects connected with the transplantation of young Portuguese from the ex-colonies. The group studied was composed of 22 cases of drug addiction admitted to the Centre for Drug Research and Prophylaxis, Coimbra, over a specified period. A qualitative and quantitative change in drug consumption and an increase in delinquent behaviour were considered of particular interest and specifically linked to transplantation. An initial analysis indicated the enormous importance of the conflict of identity which existed in the transplantation situation which was subsequently explored in more depth. Transplantation put to the test the capacity to adapt and involved profound changes in defensive mechanisms, which under unfavourable social conditions took on a distinctly regressive character. In view of the age group of the cases under study (adolescents), the frustrations resulting from transplantation were thus added to a crisis of maturation which was already regressive in itself. Some clinical examples are provided. PMID- 6913413 TI - Changes in the frequency of use and abuse of drugs by Los Angeles County methadone maintenance patients: an observation based on urine drug testings in 1975 and 1979. PMID- 6913414 TI - Differentiation and comparison of raw, prepared and dross opium. AB - Comparative studies involving colour tests, thin-layer chromatography (TLC) and gas-liquid chromatography (GLC) were made on raw, prepared and dross opium with a view to establishing means for their differentiation. Analysis of a large number of samples found in south-east Asia showed the typical patterns and results to be quite distinctive in the qualitative and quantitative aspects. The relative proportions of the major alkaloids in the two chromatographic systems were used to advantage in the comparison. Prepared opium was found to have a characteristic yellow fluorescent spot on the TLC plate when viewed under long-wavelength ultraviolet light. No positive marker was found for dross opium, its unusual features being the relatively high morphine and codeine content and the absence of narcotine, meconic acid and especially thebaine. Most of the prepared opium samples were found to have been made from a mixture of raw and dross opium. The modified hallucinogen reagent of Maunder was found to be a suitable alternative chromogenic spray in the TLC analysis. PMID- 6913415 TI - Analysis of micro-encapsulated d-limonene dimercaptan, a possible herbicide marker for Cannabis sprayed with paraquat, using gas chromatography. AB - A method for the determination of encapsulated d-limonene dimercaptan (d-LDM), a possible marker for Cannabis sativa L. sprayed with herbicide, has been developed. The methodology includes a single-step extraction, followed by gas chromatography with flame photometric detector (FDP) using n-octadecyl mercaptan (n-octadecylthiol) as an internal standard. A liner relationship was obtained from spiked samples with an average coefficient of variation of 9.0 per cent. The method has been used to determine part-per-million levels of LDM in actual field experiments in Mexico. The FDP limit was found to be 7 ng for d-LDM. PMID- 6913416 TI - Recovery, separation and purification of narcotine and papaverine from Indian opium. PMID- 6913417 TI - Patterns of self-reported drug use among secondary school students in Bendel State, Nigeria. AB - Based on a sample of nearly 1,500 secondary school students in Bendel State, Nigeria, this study shows that students disapprove of most forms of drug use among their peers and that very few of them actually use drugs. No clear evidence emerged for the use of heroin, morphine and cocaine. One finds, however, that chlordiazepoxide (Librium) and diazepam (Valium) are among the most frequently used drugs. One important finding is that there is a kind of "coalescence of drug use" in which certain drugs tend to go together. PMID- 6913418 TI - But would you want your daughter to become a nurse? Part 2. PMID- 6913420 TI - Nursing research: where are we now? PMID- 6913419 TI - Eight steps to quality assurance: Part one. PMID- 6913421 TI - Compendium of nursing research. PMID- 6913422 TI - Some commonsense suggestions for nurses new at the research game. PMID- 6913423 TI - Sjogren's syndrome a nursing perspective. PMID- 6913424 TI - Frankly speaking: primary health care: the elusive dream. PMID- 6913425 TI - You and the law: the incident report. PMID- 6913426 TI - Planning nursing interventions for family members of adult cancer patients. PMID- 6913427 TI - Skills needed by family members to maintain the care of an advanced cancer patient. PMID- 6913428 TI - Social support and health outcomes in postmastectomy women: a review. PMID- 6913429 TI - Report on a BSE educational program for lay audiences conducted by nurse health educators. PMID- 6913431 TI - Cancer nursing and the law: turning off life support. PMID- 6913430 TI - Stress inoculation training with cancer patients. PMID- 6913432 TI - Programmed instruction: cancer care: leukemia. PMID- 6913433 TI - Research highlights: responsibility and the research consumer. PMID- 6913434 TI - Pharmaceutics: predictive tests of human tumor responsiveness to chemotherapy. PMID- 6913435 TI - Cardiovascular effects of alcohol ingestion. PMID- 6913436 TI - Alcoholic cardiomyopathy. PMID- 6913437 TI - [Effect of ionizing radiation on enzymes. IV. Proteolytic effectiveness of pancreatin with an increased water content]. PMID- 6913438 TI - Studies on heterogeneous components of hog pancreatic kallikrein. II. Preliminary probe of the varied structures of carbohydrate chain of hog pancreatic kallikrein. PMID- 6913439 TI - [Goal-setting in tertiary education]. PMID- 6913440 TI - Psychosocial aspects of mammary carcinoma. PMID- 6913441 TI - [The child in the hospital: Nurse - talk and play with him]. PMID- 6913442 TI - Care of the neurogenic bladder in spinal cord injuries: criteria for urinary diversion procedure and special management problems associated with the diverted spinal injury patient. PMID- 6913443 TI - Pain. PMID- 6913444 TI - [The married woman in the nursing profession]. PMID- 6913445 TI - Important aspects of midwifery. PMID- 6913446 TI - [Ethics - respect for human life]. PMID- 6913447 TI - [Planned change]. PMID- 6913448 TI - [The adolescent student]. PMID- 6913449 TI - [The heart of nursing]. PMID- 6913450 TI - autoimmune hemolytic anemia associated with IgA autoantibody. PMID- 6913451 TI - Respiratory distress syndrome. PMID- 6913452 TI - Occupational lung diseases II. PMID- 6913454 TI - [Rehabilitation and nursing ideals (II): the comprehensive rehabilitation nursing theory and the starting point in nursing]. PMID- 6913453 TI - Assessing the work environment for agents that may cause occupational pulmonary disease. AB - The industrial hygienist is a professional trained in the resognition, evaluation, and control of environmental stresses in the workplace and as such serves as a valuable recourse for medical personnel concerned with occupational lung disease. Knowledge of the precise identity and quantity of workplace hazards is often essential in diagnosing occupational lung disorders. In addition, an industrial hygienist familiar with the process can assess whether there is a likelihood of exposure to levels above the limits which are considered to be safe. This valuable industrial hygiene information can be from government (e.g., OSHA, state agencies), universities or consulting firms. PMID- 6913455 TI - [Women's role and nursing--a lesson from folk medicine (3)]. PMID- 6913456 TI - [Constant gentleness and flexibility: advice to a new nursing director]. PMID- 6913457 TI - [Jan van den Berg in Japan--the man and his ideology]. PMID- 6913458 TI - [Broad beans in a frying pan--activities of the Youth Corps dispatched to Nepal]. PMID- 6913459 TI - [On the ideal formats of nursing and education (8)--postgraduate education (4). An experience with a 5-day clinical training course]. PMID- 6913460 TI - [Health is everybody's business]. PMID- 6913461 TI - Self-care in sickness and in health. PMID- 6913462 TI - Mastectomy. PMID- 6913463 TI - Mastectomy: woman to woman. PMID- 6913464 TI - Respiratory care update! Tuberculosis. PMID- 6913465 TI - Field management of hypertensive emergencies. PMID- 6913466 TI - Therapy of experimental infective endocarditis due to antibiotic-tolerant Lactobacillus plantarum-bactericidal synergy of penicillin plus gentamicin. Correlation of in vitro susceptibility studies with in vivo efficacy. AB - Infective aortic valve endocarditis (IE) was induced in 40 rabbits with a penicillin (PNC)-tolerant, gentamicin (GM)-resistant strain of Lactobacillus plantarum; this isolate was synergistically killed in vitro by PNC + GM. The in vivo relevance of the in vitro observations was examined by determining the rates of eradication of endocardial L. plantarum by PNC versus PNC + GM. Mean vegetation L. plantarum titers were significantly lower (p less than 0.05) in PNC + GM treated rabbits versus both PNC-treated and control rabbits by 48 h of therapy. Also, PNC + GM more rapidly sterilized vegetations as compared to controls (p less than 0.025) and PNC-treated rabbits (p less than 0.05). Thus, in vivo antibiotic efficacy paralleled in vitro bactericidal studies, and may partially explain the relatively refractory nature of lactobacillary IE in humans treated with single beta-lactam antibiotics. PMID- 6913467 TI - Shortage of chemical fuel as a cause of fatigue: studies by nuclear magnetic resonance and bicycle ergometry. AB - The technique of nuclear magnetic resonance (n.m.r.) is briefly described to illustrate its use for estimating metabolite levels in vivo. Our studies of fatigue in anaerobic frog muscle at 4 degree C are described in relation to (a) force development, (b) speed of relaxation and (c) the switching on and off of glycolysis. Both (a) and (b) are closely related, though in different ways, to the concentrations of key metabolites. In contrast, (c) is not related to metabolite levels as such but to the events of contraction and relaxation. A special n.m.r. technique (saturation transfer) has been used to study the creatine kinase system in vivo. The results show that this system is highly active and is in equilibrium in resting muscle. The free [ADP] is consequently only a small fraction of that found by analysis of muscle extracts. Studies of human power production as a function of duration of exercise also indicate that it is shortage of chemical fuel that brings short- and medium-term exercise (0.1 10 min) to a halt. It is proposed to extend n.m.r. methods to human subjects in the near future. A working hypothesis to account for fatigue is suggested in which both the contractile system and the activating system play a part. PMID- 6913468 TI - EMG and fatigue of human voluntary and stimulated contractions. AB - During a 60s maximal voluntary isometric contraction (MVC) of the adductor pollicis muscle the loss of force is accompanied by a parallel decline in both the integrated surface electromyogram (EMG) and the single muscle fibre spike counts recorded intramuscularly. This decline is not due to neuromuscular block since the muscle mass action potential (M wave) evoked by single maximal shocks to the nerve is well maintained; nor does the size of the single fibre spike change. It must, therefore, reflect a decline in the firing pattern of the motor neuron pool. The force of a sustained MVC continues to match that from maximal tetanic nerve stimulation; thus, all motor units remain active. Continuous nerve stimulation at the frequency required to match the voluntary force of unfatigued muscle leads to a progressive failure of the M wave, and a more rapid force loss than in an MVC. Both are largely restored by reducing the stimulus frequency. The decline in neural firing rate correlates well with the rate of muscle contractile slowing. It thus optimizes force by maintaining a relatively constant degree of tetanic fusion, while avoiding peripheral failure of electrical propagation. PMID- 6913469 TI - Firing properties of single human motor units on maintained maximal voluntary effort. AB - The discharge properties on maintained maximal voluntary effort, axonal conduction velocity (a.c.v.) and contraction time (c.t.) of single human motor units were studied. Electromyographic (EMG) techniques were used and sufficient selectivity was obtained after repeated lesions to the terminal nerve twigs and consequent collateral sprouting, or by blocking the main muscle nerve in subjects with an accessory nerve supplying just one or a few units, or using high impedance wire electrodes. Most units with a.c.v. above 45 m/s and c.t. below 50 ms had maximal voluntary firing rates of about 50 Hz. On prolonged maximal effort, however, their rates rapidly decreased and after some seconds to a minute they ceased to respond tonically. As long as their motoneurons fired their EMG potentials were mainly intact and their twitch tension was significant. Most units with a.c.v. below 40 m/s and c.t. above 60 ms fired initially at 30 Hz, decreased slowly in firing rate and continued at 20 Hz for some minutes. We conclude that there is a central fatigue of units with short c.t. and high a.c.v. which protects their peripheral regions from severe exhaustion, but that there is no significant central fatigue of units with long c.t. and low a.c.v. We emphasize, however, that most units are intermediate in their properties. PMID- 6913470 TI - Muscle fatigue due to changes beyond the neuromuscular junction. AB - A number of changes in function occur beyond the neuromuscular junction during activity; three main types are described. (a) During high frequency stimulation there is a rapid loss of force accompanied by a slowing of the action potential waveform and an increase in the excitation threshold of the muscle. It is suggested that accumulation of K+ in the extracellular spaces of the muscle may be responsible for these changes. (b) Slowing of relaxation is a feature of fatigued muscle. The slowing allows a reduction in activation frequency (minimizing high frequency fatigue) without resulting in an appreciable loss of force. (c) Changes in shape and amplitude of the twitch have considerable effects on the force generated by low frequencies of stimulation. After a brief tetanus there is a reduction in the width of the twitch which increases the fusion frequency of the muscle and may account for the "sag' seen at the start of low frequency contractions. After a prolonged series of contractions the twitch amplitude is reduced and remains so for several hours. This may be the result of some structural damage to the sarcoplasmic reticulum or transverse tubular system. PMID- 6913471 TI - Contractile function and fatigue of the respiratory muscles in man. AB - Ventilation depends on the proper functioning of the respiratory muscles. These muscles, like other skeletal muscles, can endure high work loads for only short time periods. The work of breathing in patients with lung disease in increased and it has therefore been argued that respiratory muscle fatigue may develop and contribute to respiratory failure. We have studied the contractile function and fatigue of the sternomastoid muscle and the diaphragm in normal subjects and found that these respiratory muscles have the same contractile properties as limb muscles. If subjected to a high load they develop similar patterns of fatigue. Studies on the sternomastoid muscle in patients with lung disease also confirmed that respiratory stress produces fatigue. PMID- 6913472 TI - Neural drive and electromechanical alterations in the fatiguing diaphragm. AB - It is suggested that respiratory failure in the compromised circulation might occur as a result of respiratory muscle fatigue in the presence of adequate neural drive and muscle excitation. As the cardiac output decreases acidosis develops and ventilation increases, resulting in an increase in the work of breathing, which requires the delivery of large supplies of energy. As these demands cannot be met by the energy supply, because of low cardiac output, the diaphragm fails as a force generator and respiratory failure ensues. Diaphragmatic fatigue may occur in normal subjects if the pressure developed with each breath is greater than 40% of the maximum transdiaphragmatic pressure and hypoxia predisposes the diaphragm to fatigue. Diaphragmatic fatigue, as in other skeletal muscles, might be located either at the neuromuscular junction or distal to it and can be detected either by phrenic stimulation or by frequency analysis of the myoelectric signal. Phrenic stimulation shows that after fatigue the diaphragm develops less force at any frequency of stimulation, but the loss of force at low frequencies persists for a longer period than at high frequencies. Frequency analysis of the electromyogram reveals that the power spectrum shifts to lower frequencies. This shift occurs long before the diaphragm fails as a force generator. PMID- 6913473 TI - The tremor in fatigue. AB - After a maximal voluntary effort made for about 2 min, tremor of the muscles concerned is increased in amplitude by up to one order of magnitude for a period of several hours afterwards. Spectral analysis reveals that all frequencies of tremor show this increase. Maximal electrical stimulation of the motor nerve to the muscle does not result in any change in tremor so it is inferred that the increase is due to the operation of spinal or supra-spinal mechanisms. A sub maximal voluntary effort, maintained for about 1 h, leads to the development of large amplitude, low frequency tremor (4-6 Hz) in addition to increased physiological tremor (8-12 Hz). It is generally accepted that physiological tremor originates as an oscillation in the reflex arc servo loop. The 4-6 Hz slow tremor of this type of fatigue also appears to arise as servo loop oscillation, the feedback delays being longer than in physiological tremor. The spectrum of the slow tremor resembles that found in Parkinsonism and it may be useful model for the tremor of that condition. PMID- 6913474 TI - The pathophysiology of inspiratory muscle fatigue. AB - The critical value of the rate of energy consumption of the inspiratory muscles above which fatigue occurs appears in some instances to be predictable from the relationship between energy demands and energy supplies rather than from the percentage of fatigue-resistant fibres in the inspiratory muscles. When this is the case the critical value of the external power produced by the inspiratory muscles is given by the product of muscular efficiency and the rate at which energy is supplied. Efficiency is reduced by hyperinflation and recruitment of the intercostal and accessory muscles of inspiration. The rate at which energy is supplied is decreased in states characterized by low cardiac output. The condition of low cardiac output, combined with the high oxygen cost of breathing against fatiguing loads, may be lethal in cardiogenic shock. Although the immediate cause of fatigue may not be related to reduced energy supplies, clinically useful predictions of conditions predisposing to fatigue result from an understanding of factors determining the balance between the energy demands and supplies of the inspiratory muscles. These predictions aid in the diagnosis of inspiratory muscle fatigue and have important therapeutic implications. PMID- 6913475 TI - Fatigue in human metabolic myopathy. AB - The ability of muscle fibres to sustain force can be related to their economy of energy utilization and to their capacity to regenerate energy under the prevailing conditions (aerobic or anaerobic) of contraction. The pathophysiology of muscle fatigue is analysed in patients with thyroid dysfunction and with impaired glycogenolysis, and in a patient with abnormal mitochondrial function. Muscle from hypothyroid patients, like cooled muscle, is slow in relaxing and shows a reduced energy requirement (energy economy) and reduced fatiguability, whereas muscle of hyperthyroid patients may show the opposite features. In myophosphorylase deficiency the energy economy is normal in the fresh state and increases as contraction proceeds; however, fatigue is premature and associated with impaired excitation rather than an overall depletion of energy stores. With abnormal mitochondrial function the muscle tends to be effectively anaerobic and fatigue is associated with impaired excitation-contraction coupling. This appears to result from either muscle ischaemia or the dominant use of anaerobic metabolism for energy regeneration. Fatigue in these disorders of energy metabolism may ultimately be due to a reduced supply of ATP but direct evidence of this is lacking and, if it occurs, its physiological expression is probably variable. PMID- 6913476 TI - The perception of fatigue. PMID- 6913477 TI - Muscle fibre recruitment and metabolism in prolonged exhaustive dynamic exercise. AB - The rather constant amount of glycogen found in all fibre types in human skeletal muscle provides an opportunity to study the pattern of glycogen depletion with exercise, which should give an indication of which fibres are activated to generate the force. In very light dynamic contractions repeated for hours there is a primary reliance on slow twitch (ST) fibres with no or very minor involvement of fast twitch (FT) fibres. At heavier work loads (greater than 50% Vo2max) ST fibres are depleted first but FT fibres begin to become depleted. Exhaustion at these work levels coincides with muscle fibres of all types being depleted of glycogen. The crucial role of muscle glycogen in both the metabolic response to exercise and work performance is apparent. It is more difficult to explain why extramuscular substrates (plasma free fatty acids) cannot be utilized at a high enough rate to accommodate the energy turnover needed in more intense dynamic exercise. A limitation on the uptake of free fatty acids by the muscle cell rather than its transport to the cell or oxidation within it appears to be the critical factor. PMID- 6913478 TI - Relevance of muscle fibre type to fatigue in short intense and prolonged exercise in man. AB - It has been suggested that the histological and histochemical features of human muscle are important in determining performance capacity. The relationship between muscle fibre types (Type I, slow twitch fibres; Type II, fast twitch fibres) and performance on standardized tests has been studied in subjects accustomed to physical exercise, and related to their patterns of lactate metabolism, expressed as the onset of blood lactate accumulation (OBLA). This variable was found to be the best predictor of endurance capacity of the variables studied. It is suggested that in healthy male subjects muscle lactate is crucial in short, intense forms of exercise (the higher the lactate formation, the better the performance) and also in prolonged, "endurance' forms of exercise (the later the onset of lactate formation, the higher the sustainable exercise intensity). In subjects with a high proportion of fast twitch fibres, more lactate will be formed at the same exercise intensity. This is advantageous for short intense exercise but impairs endurance performance. The deleterious effects induced by glycogen depletion were studied and found to be most pronounced in subjects rich in fast twitch (glycogen-dependent) fibres. Indications were also obtained that muscular performance is regulated in different ways in males and females. In women an inverse relationship was found between fast twitch fibres and muscle power, and between fatigue and lactate concentration, whereas direct relations were found in men. PMID- 6913479 TI - Effect of metabolic changes on force generation in skeletal muscle during maximal exercise. AB - During vigorous, strong contractions there is a rapid decline in the mechanical output or tension development in skeletal muscle. Several studies have indicated that this rapid decline in force development (often referred to as fatigue), is caused by metabolic changes in the muscles. During brief intense exercise there is a rapid breakdown of phosphocreatine and glycogen and a concomitant increase in the lactate and hydrogen ion concentration. The muscle lactate concentration is increased from about 1-2 mmol kg-1 wet weight at rest before exercise to approximately 25-30 mmol kg-1 wet weight immediately after intensive brief exercise to exhaustion. The muscle pH (i.e. the pH of muscle homogenates) falls from about 7.0 at rest to approximately 6.4 at exhaustion. The changes in the concentrations of ATP, ADP, and AMP are small. It is suggested that the changes in intracellular pH might affect the force generation of skeletal muscle by two different mechanisms: (1) The fall in intracellular pH reduces the activity of key enzymes in glycolysis, thus reducing the rate of ATP resynthesis, and (2) the increased hydrogen ion concentration has a direct effect on the contractile processes, thus reducing the rate of ATP utilization. It is suggested that the increased hydrogen ion concentration might be the common regulator for the maximal rate at which ATP is being utilized and the maximal rate at which it is being resynthesized. PMID- 6913480 TI - The glucose/fatty acid cycle and physical exhaustion. AB - The energy required for sustained exercise is provided by the oxidation of two fuels, glucose and long-chain fatty acids, which are stored as liver and muscle glycogen and adipose tissue triglyceride. The latter provides the largest energy reserve in the body; there is sufficient energy for about five days of continuous marathon running. Glycogen reserves, in contrast, are very limited and, at most, could provide energy for 100 minutes. Evidence is presented of a metabolic limit in the rate of fatty acid utilization, so that sustained exercise at a high power output requires the utilization of both fat and carbohydrate simultaneously. There is a regulatory mechanism by which fatty acid oxidation reduces carbohydrate utilization in muscle--the glucose/fatty acid cycle. This plays an important part in ensuring that marathon runners can continue beyond the theoretical limit of 100 minutes. Triglyceride is mobilized from adipose tissue as long-chain fatty acids and the oxidation of these by muscle reduces the rate of glucose utilization. The availability of fatty acids for oxidation as early as possible in exercise will allow the use of both fuels (fatty acids and glucose) for a longer period of time. Since it appears that fatigue occurs when carbohydrate reserves are depleted, reduction in the rate of glucose utilization by the oxidation of fatty acids is obviously beneficial. The ability of ultra distance runners to exceed these limits poses interesting metabolic questions relating to exhaustion. PMID- 6913482 TI - Development of the autonomic nervous system. PMID- 6913481 TI - Current approaches to development of the autonomic nervous system: clues to clinical problems. AB - A number of different approaches to autonomic development utilizing a variety of experimental models and analytical techniques have been outlined. A scheme, which attempts to delineate a series of events involving separate but sometimes overlapping mechanisms, is proposed for the complex process of formation and maintenance of functional autonomic neuroeffector junctions. The relevance of these basic mechanisms of a variety of clinical abnormalities of autonomic function is discussed. PMID- 6913483 TI - Growth and development of sympathetic neurons in tissue culture. AB - Adrenergic neurons from the superior cervical ganglion of the neonatal rat, when studied under certain culture conditions, develop cholinergic properties including hexamethonium-sensitive synaptic interactions, choline acetyltransferase activity and synaptic endings containing clear vesicles. Evidence from correlative biochemical, physiological and morphological studies on populations of neurons indicates that cholinergic function is acquired by the majority of neurons and not by subpopulation. The factors that influence the development of cholinergic function in culture include the presence of non neuronal cells, the addition of human placental serum and chick embryo extract to the culture medium as well as the stage of development at which the neurons are placed in culture. Neurons from mature rats, maintained as explants in culture, develop low choline acetyltransferase activity and the synaptic endings containing dense-cored vesicles. In contrast, if dissociated, these adult neurons develop several cholinergic characteristics. Studies to determine which adrenergic properties are retained in neurons expressing cholinergic characteristics have shown an increase in the activities of tyrosine hydroxylase and dopamine beta-hydroxylase in both explanted and dissociated perinatal neurons. In addition, tyrosine hydroxylase has been localized immunocytochemically in neurons identified as cholinergic by electrophysiological methods. PMID- 6913484 TI - Adrenergic-cholinergic dual function in cultured sympathetic neurons of the rat. AB - Sympathetic principal neurons, dissociated from the superior cervical ganglia of newborn rats and put into culture, exhibit plasticity with respect to the choice between noradrenaline (norepinephrine) and acetylcholine as transmitter. The neurons shift from an initial, immature adrenergic state to a cholinergic state in certain culture conditions, e.g in co-culture with a variety of non-neuronal cells or after exposure to a medium conditioned by such cells. To study the transition directly, we have grown single neurons in "microcultures" with cardiac myocytes, which provide a sensitive assay for the transmitters secreted by the neurons. We have shown previously that during the transition from adrenergic to cholinergic status such neurons secrete both transmitters and have terminals of mixed fine structure (dual function). We describe here experiments in which identified neurons were serially assayed over periods of 9-45 days. Partial transitions were observed, always in the direction adrenergic to cholinergic function, and one complete transition was observed from apparently purely adrenergic function to dual function and then to apparently purely cholinergic function. We also report observation of adrenergic-cholinergic dual function, in preliminary single and serial assays, in sympathetic principal neurons from the superior cervical ganglia of adult rats. PMID- 6913485 TI - Factors regulating growth of catecholamine-containing nerves, as revealed by transplantation and explantation studies. AB - Intraocular grafting of various types of neuron and target tissue shows that peripheral and central noradrenergic neurons may substitute morphologically and functionally for each other in certain, but not all, target tissues. The morphology of growing adrenergic nerve terminals, their patterning, and the number of fibres are completely determined by the target tissues. Thus, the sympathetic adrenergic neuron of an adult organism is a highly plastic unit which may, for instance, double or even triple its terminal field in response to new demands from the environment. Several differences exist between central and peripheral adrenergic nerves: locus coeruleus will not innervate heart grafts; sympathetic fibres will not innervate the spinal cord; and central adrenergic neurons are not sensitive to nerve growth factor (NGF). Chromaffin cells can be made to innervate peripheral and central targets. No NGF is detected in normal adult iris. The iris responds to grafting, explantation, and to sensory or sympathetic denervation with rapid production of NGF as shown by bioassays on chick embryonic ganglia. This iris also contains a potent stimulatory factor for the ciliary ganglion. Trauma to the iris or to the anterior eye chamber may cause it to become hyperinnervated. Heavy metals have characteristic and different effects on the sympathetic nerves of the iris: lead and manganese causes hyperinnervation; cadmium does not change the number of nerves; while mercury causes severe terminal degeneration followed by regeneration. PMID- 6913486 TI - Regulation of synaptic connections in the rabbit ciliary ganglion. AB - One of the intriguing questions about the establishment of synaptic connections is how appropriate numbers of different axons come to innervate each target neuron. A reorganization of connections in early postnatal life appears to be an important aspect of this process, since many of the axons terminals that initially innervate target cells are subsequently lost. The rabbit ciliary ganglion is a remarkably simple neural ensemble in which to examine this rearrangement of developing synaptic connections. Using this system we have found that a reduction in the number of axons innervating each cell occurs without any change in the number of ciliary ganglion cells or preganglionic neurons; therefore the rearrangement is not based on cell death. The number of different axons that ultimately innervate each cell is, however, influenced in some way by the geometry of individual target neurons. Thus, mature ganglion cells that lack dendrites are generally innervated by a single axon, while neurons with increasingly complex dendritic arbors receive innervation from a commensurate number of different axons. At birth, on the other hand, neurons with or without dendritic processes receive about the same number of preganglionic inputs. These results suggest that the geometry of the target cell influences the competitive interaction between different axons innervating the same neuron. Indeed, an important function of dendrites may be to regulate the number of axons that innervate each nerve cell. PMID- 6913487 TI - Pregnancy induces degenerative and regenerative changes in the autonomic innervation of the female reproductive tract. AB - The uterus is supplied with an extensive system of adrenergic nerves. The neurobiological properties of this innervation have been investigated in a series of studies primarily using the guinea-pig as model. The guinea-pig uterus is supplied from three different sources: the paracervical plexus, containing short adrenergic neurons; the inferior mesenteric ganglion; and a cranial source, probably the aorticorenal plexus, via nerves in the uterine suspensory ligaments. The nerve density is higher in the tubal end of the uterine horn and in the cervix than in the main part of the uterine horn. The turnover rate of transmitter is lower in the uterus than in a control organ, such as the heart. Noradrenaline levels in the uterus, but not the heart, are influenced by alterations in the endocrine milieu, e.g. during the oestrous cycle and after treatment with sex steroids. In the uterine tissue surrounding the conceptus during pregnancy, there is an early and drastic decay in various functional parameters related to the adrenergic nerve plexus and primarily reflecting a local, pregnancy-induced axonal degeneration. In the main part of the empty horn, in unilateral pregnancy, there is an extensive decay in various adrenergic functional parameters; these, however, reflect changes in a nerve plexus that has an essentially intact structure. No sign of functional impairment is seen in the adrenergic nerves of the uterine cervix. The increased turnover rate and reduced transmitter content in this region during late pregnancy may reflect increased frequency of firing of the adrenergic nerves. The tubal end of the uterine horn shows no signs of altered sympathetic function. This is the only part of the uterine horn that appears unaffected by pregnancy. The deficient recovery post partum of the changes in the uterine horn that previously contained the fetuses suggests permanent damage to the adrenergic nerve plexus after a pregnancy. The post partum recovery of changes seen in the previously empty horn, however, is more pronounced but still incomplete by comparison with the innervation before pregnancy. Studies on the adult human uterus indicate that similar events to those described for the guinea-pig model occur in human pregnancy. PMID- 6913488 TI - Myenteric plexus of the hind-gut: developmental abnormalities in humans and experimental studies. AB - Intraluminal pressure studies on patients with congenital aganglionosis showed that the aganglionic rectum contracted in an uncoordinated manner and failed to relax. Histochemical assessment of the innervation helped to explain the variable severity of the symptoms in this condition. It is concluded that (1) absence of ganglia prevents normal coordinated peristalsis and creates an obstructive element; (2) absence of reflex relaxation adds to the obstruction; (3) the degree of uncoordinated motor activity in distal aganglionic bowel probably relates to the number of cholinesterase-positive nerves in the circular muscle and adds another variable obstructive element; and (4) deficient innervation of distal ganglionic bowel probably creates a poor propulsive force and so accentuates more distal obstructive factors. Neurohistochemical and functional studies in the anorectum of cats reveal a somewhat different innervation pattern from that in humans but show that sphincteric tone is mainly due to alpha-adrenergic neural activity. Reflex relaxation of the internal anal sphincter is a complex function in which inhibitory responses override motor responses, and it involves an important non-adrenergic non-cholinergic component. The role of cholinergic nerves in the sphincter remains uncertain. Neurohistochemical assessment of full thickness biopsy specimens of rectal muscle from patients with disabling constipation shows that developmental neuronal dysplasias of the hind-gut may be divided into three main categories: (1) aganglionosis (Hirschsprung's disease), (2) hypoganglionosis and (3) hyperganglionosis, and that the different neuronal elements may be affected to differing degrees in individuals within each group. Resection of the aganglionic bowel is required in congenital aganglionosis but the combined diagnostic-therapeutic procedure of anorectal myotomy has been found beneficial in patients with hypoganglionosis. PMID- 6913489 TI - Development of enteric neurons from non-recognizable precursor cells. AB - Precursors of the neurons that populate enteric ganglia cannot be recognized morphologically when they first enter the gut; therefore embryonic gut in culture, explanted before neurons appear, develops a myenteric plexus that contains cholinergic and serotonergic neurons. The evidence indicates that the developing gut maintains an immature proliferating pool of neuronal precursors that may tentatively and transiently express a given neuronal phenotype. Catecholaminergic expression is an example of such a transient phenotype. It is possible that sequential changes, occurring as a function of gestational age in the enteric neuronal microenvironment and interacting with this persistent pool of neuronal precursors, are responsible for the generation of enteric neuronal diversity. The sequential appearance of the various types of enteric neuron is consistent with this hypothesis. The persistence of a dividing cell population may also be linked to the generation of the large number of enteric neurons. PMID- 6913490 TI - Autonomic regulation of cardiovascular function in neonates. AB - The degree of participation of the vascular bed supplied by the superior mesenteric artery in autonomic regulation of cardiovascular function during postnatal maturation was evaluated in piglets, ranging in age from birth to two months. Animals were anaesthetized with 0.25-0.5% halothane in a 50% mixture of N2O and O2, paralysed with decamethonium bromide and artificially ventilated to maintain normal arterial blood gases and pH. Mesenteric arterial flow was recorded continuously with an electromagnetic flow transducer; simultaneously aortic pressure, heart rate, and femoral, renal and carotid flows were monitored. Resistance was calculated as the ratio of mean aortic pressure to mean flow. The central neural regulation of the cardiovascular system was altered: (1) by electrical stimulation of medullary vasoactive sites, (2) by changing the input from visceral or somatic afferents and (3) by subjecting the animals to stress, such as haemorrhage or hypoxia. Postnatal development of adrenergic mechanisms was studied with the aid of adrenergic agonist both in vivo and in vitro (helical strips cut from superior mesenteric artery were placed in an organ bath for isometric tension recordings). Recordings of spontaneous efferent splanchnic discharge permitted a more direct examination of autonomic regulation of the mesenteric vascular bed. The results indicate that the vascular bed supplied by the superior mesenteric artery and innervated by the efferent splanchnic nerve is actively involved in the cardiovascular responses to alterations in the cardiovascular regulatory system. Furthermore, this vascular bed may have an inappropriate response to both feeding and stress such that pathological changes in the gastrointestinal tract may result. PMID- 6913491 TI - Counseling parents of seriously ill children. PMID- 6913492 TI - Stress and psychological problems of patients undergoing APR. PMID- 6913493 TI - Wound healing: a review. I. The biology of wound healing. PMID- 6913494 TI - Interview with Rolf Benirschke: ileostomate and second leading 1980 NFL scorer. Interview by Philip Pressel. PMID- 6913495 TI - Techniques for use of a new dressing - a moisture vapor permeable film. PMID- 6913496 TI - Standards of enterostomal nursing practice. PMID- 6913497 TI - Role of exposed cytosine residues in aminoacylation activity of tRNATrp. PMID- 6913498 TI - [Diet therapy in ischemic heart disease]. PMID- 6913499 TI - [Convulsion syndrome in young infants]. PMID- 6913500 TI - [Drug allergy in children (2. its diagnosis, treatment and prevention)]. PMID- 6913501 TI - [Strangulated hernias]. PMID- 6913502 TI - [Deontological aspects of the treatment of middle-aged and elderly patients]. PMID- 6913503 TI - [Congenital absence of the fibula]. PMID- 6913504 TI - [Extrauterine pregnancy]. PMID- 6913505 TI - [Sociomedical aspects of the world birth rate]. PMID- 6913506 TI - [Basic trends of health education work in the prevention of infectious diseases]. PMID- 6913507 TI - [Discussion of books as a method of raising the qualifications of paramedical workers]. PMID- 6913508 TI - [Characteristics of the spread of bartonellosis and the measures for its prevention]. PMID- 6913509 TI - [Shingles: herpes zoster]. PMID- 6913510 TI - [Hemorrhaging cervix erosion: suspicion of cervical cancer]. PMID- 6913511 TI - [Hypertensive crisis]. PMID- 6913512 TI - [Acute respiratory insufficiency in children]. PMID- 6913513 TI - [Perforated gastric and duodenal ulcer]. PMID- 6913514 TI - [Periodontal diseases]. PMID- 6913515 TI - [Clinical aspects, treatment and prevention of thiuram-induced poisonings]. PMID- 6913516 TI - [Varieties of pemphigus]. PMID- 6913517 TI - [Health center work organization in an industrial enterprise]. PMID- 6913518 TI - [Prehospitalization differential diagnosis of acute appendicitis]. PMID- 6913519 TI - [Medical first aid in open fractures of the bones of the extremities]. PMID- 6913520 TI - [Diphtheria today and its prevention]. PMID- 6913521 TI - [Problems of health protection for women and children in the developing countries]. PMID- 6913523 TI - [Work organization of the paramedical personnel in a school]. PMID- 6913522 TI - [Attempt at making nursing infants physically fit through swimming]. PMID- 6913525 TI - [Cancer of the fallopian tubes]. PMID- 6913524 TI - [Breech presentation, premature membrane rupture and chorioamnionitis]. PMID- 6913526 TI - [Drug agranulocytosis]. PMID- 6913527 TI - [Food value and health properties of milk fat]. PMID- 6913528 TI - [Special nursing aspects in urology. Congenital urological disorders]. PMID- 6913529 TI - [Systematic nursing actions]. PMID- 6913530 TI - [Special nursing aspects in urology. Introduction to urodynamics]. PMID- 6913531 TI - [Aggressiveness in the caregiver. 1]. PMID- 6913532 TI - Talk back. Interview by Charlie Wilson. PMID- 6913533 TI - BEAVOR--on the spur, Good Buddy! PMID- 6913534 TI - A summer spent with FNS. PMID- 6913535 TI - A different kind of nurse. PMID- 6913536 TI - The certified nurse-midwife: the professional midwife in the United States. PMID- 6913537 TI - Entry into practice: a career entry guide for nurses. PMID- 6913538 TI - Career opportunity profiles. PMID- 6913539 TI - Don't cop out - hang in! PMID- 6913540 TI - Release of activatable kallikrein by isolated rat kidneys. AB - Rat isolated kidneys were perfused for 60 minutes with a modified Krebs-Henseleit bicarbonate solution. Perfusate and urine samples showed kininogenase activity (active kallikrein) which could be enhanced by activation with trypsin (activatable kallikrein). Identification of the kininogenase activity generated by trypsin was made with rat renal kallikrein antiserum, aprotinin, lima bean trypsin inhibitor (LBTI), soybean trypsin inhibitor (SBTI), and ovomucoid. A sample of perfusate was partially purified through DEAD-Sephacel chromatography. Intraarterial injection of this fraction decreased blood pressure in the perfused hind limb of a rat. PMID- 6913541 TI - Kinin-forming enzyme of rat cardiac tissue. Subcellular distribution and biochemical properties. PMID- 6913542 TI - Effect of renal nerve stimulation on urine and tissue kininogenase activity in cats. AB - The effect of electrical stimulation of efferent renal nerves on urine and renal tissue kininogenase activity was studied in cats. Handling renal nerves before crushing produced a significant increase is mean blood pressure (BP) in intact animals. After crushing, stimulation of efferent fibers (15 V, 0.5 msec, and 25 Hz) by 15-second train duration and at 2.45-minute intervals did not alter the average renal blood flow (RBF) or BP over 30 minutes. Glomerular filtration rate, water, and potassium excretion rates did not change significantly in either kidney. Sodium excretion in the ipsilateral kidney decreased significantly (p less than 0.05) in both intact and adrenalectomized cats. In intact animals, the kininogenase activity of urine (UK) also decreased significantly in both kidneys during nerve stimulation. In adrenalectomized animals it decreased significantly (p less than 0.05) only in the ipsilateral kidney, and UK of the ipsilateral kidney was significantly lower than in the contralateral (p less than 0.05). In both groups of cats, UK returned to control values during the recovery period of 30 minutes after stimulation. Adrenergic blockade abolished the effect of nerves stimulation on sodium and UK. Renal tissue kininogenase activity (RK) per gram of wet tissue was significantly lower in adrenergically blocked animals. No differences were detected when comparing RK content of ipsilateral vs a release of adrenal and peripheral nerve ending catecholamines. PMID- 6913543 TI - Intake and health effects of thallium among a population living in the vicinity of a cement plant emitting thallium containing dust. AB - In order to assess the degree of thallium exposure in a population living around a thallium emitting cement plant in a small city in North-West Germany thallium levels in 24 h urine samples of 1,265 subjects and in hair samples of 1,163 subjects were determined. Urinary thallium levels in two groups of subjects living in an urban and a rural area of West Germany were determined for reference. As compared to these subjects the population living around the cement plant exhibited obvious signs of increased thallium intake. The mean urinary thallium concentration was 2.6 micrograms/l and ranged up to 76.5 micrograms/l. In contrast, the mean urinary thallium levels of the two reference groups were 0.2 and 0.4 micrograms/l, respectively. Hair thallium levels of the population living around the cement plant were also markedly increased (mean: 9.5 ng/g). The major route of the population's increased intake of thallium was found to be the consumption of vegetables and fruit grown in private gardens in the vicinity of the cement plant. As was shown by chemical analyses vegetables and fruit grown in these gardens were contaminated by thallium-containing atmospheric dust fall-out caused by emissions of the cement plant. The pulmonary route of uptake as well as other sources did not seem to play a significant role in the population's exposure to thallium. Polyneuritic symptoms, sleep disorders, headache, fatigue and other signs of psychasthenia were found to be the major health effects associated with increased thallium levels in urine and hair. No positive correlation was found between the thallium levels in hair and urine and the prevalence of skin alterations, hair-loss and gastro-intestinal dysfunctions. PMID- 6913544 TI - Inhibition of the classical and alternative pathways of human and guinea pig complement by pyran copolymer. AB - The ability of pyran copolymer to interact with the classical and alternative pathways of complement was assessed in human and C4-deficient guinea pig serum. Pyran induced a dose-dependent inhibition of hemolytic activity in both serum systems. Immuno-electrophoretic analysis of pyran-treated human serum revealed that C3 was not cleaved. Factor B was altered into a more anionic mobility which was not similar to biologically cleaved Ba or Bb fragments. Pyran-treated serum was unable to lyse antibody-coated erythrocytes (EA or EA coated with C1 and C4 and EA coated with C1, C4 and C2. Pretreatment of serum with ethylenediaminetetraacetic acid did not prevent inhibition of hemolytic activity by pyran. Cobra venom factor did not cleave C3 in the presence of pyran. These data indicate that pyran does not activate complement by standard mechanisms but does inhibit one or more of its components. PMID- 6913545 TI - Rubella policies for hospitals and health workers. PMID- 6913546 TI - Excessive levels of gram-negative bacteria in hemodialysis machines because of inadequate cleaning guidelines. AB - The possibility of sepsis or pyrogenic reaction increases in hemodialysis patients as coliform or other gram-negative counts in the dialysis water reach levels greater than or equal to 1000 colonies/ml. After the introduction of Cobe Century II dialysis machine (Cobe, Lakewood, Colorado), routine testing of dialysis water samples revealed gram-negative bacteria in concentrations up to 45,000 colonies/ml. An epidemiologic investigation was performed to determine the source of the bacterial contamination. The amounts of disinfectant solution were increased, but bacterial counts remained unacceptably high. A study of the fluid path within the machines revealed that part of that path was not reached at all by the disinfectant. In addition, the disinfectant was automatically and improperly diluted. Therefore, increased bacterial counts could not be reduced satisfactorily by using the manufacturer's disinfection guidelines. PMID- 6913547 TI - Rubella immunization of hospital personnel: a debate. PMID- 6913548 TI - Disruption of family unity from an adverse reaction to tetracycline. PMID- 6913549 TI - Analysis of covariance with infection. PMID- 6913550 TI - Recommendations for the control of rubella within hospitals. PMID- 6913551 TI - Influence of the Holy Spirit. PMID- 6913552 TI - Choosing a test service for the NCSBN. PMID- 6913553 TI - An experiment with personal-space invasion in the nurse-patient relationship and its effect on anxiety. PMID- 6913554 TI - A study of the relationship between adolescent pregnancy and life-change events. PMID- 6913555 TI - The battered woman: guideline for effective nursing intervention. PMID- 6913556 TI - The relationship of family concept to individual self-esteem. PMID- 6913557 TI - Outcomes of referrals of alcoholics in crisis. PMID- 6913558 TI - Treatment of sleep problems: the use of behavioural modification techniques by health visitors. PMID- 6913559 TI - Evaluation of yogurt as a weaning food. PMID- 6913560 TI - Obesity. PMID- 6913561 TI - Helping people to lose weight. PMID- 6913562 TI - Child minding--which children get a poor service? PMID- 6913563 TI - 'Sharing and caring'--a course for mothers. PMID- 6913564 TI - Know your organization. Beginners only: a first-time mothers' group. PMID- 6913565 TI - Know your organizations: Child Accident Prevention Committee. PMID- 6913566 TI - Intra-aortic balloon counterpulsation in acute myocardial infarction. PMID- 6913567 TI - Oxygen insufflation during endotracheal suctioning. PMID- 6913568 TI - Fiberoptic bronchoscopy in the intensive care unit. PMID- 6913569 TI - Survey of critical care nursing practice. Part I. Characteristics of hospitals with critical care units. PMID- 6913570 TI - Survey of critical care nursing practice. Part II. Unit characteristics. PMID- 6913571 TI - Observation on computers in an intensive care unit. PMID- 6913573 TI - Clubbing of the fingers, with special reference to Schamroth's diagnostic method. PMID- 6913572 TI - A comparative study of the effects of documentation on arrhythmia detection efficiency. PMID- 6913574 TI - Incidence, degree, and duration of postcardiotomy delirium. AB - This study investigated the relationship of incidence, degree, and duration of PCD to age of the patient, time on cardiopulmonary bypass, mean arterial pressure on bypass, ICU time, and body temperature postoperatively. The study sample consisted of 50 open-heart surgery patients. The delirium assessment was made each evening for 7 days after operation. Manifestations of delirium were experienced by 72% of the sample. Incidence of PCD was related to blood pressure on bypass, age, and temperature on the third postoperative day. Using these variables as well as temperature on the first postoperative day, delirium was accurately predicted in 76% of the patients. Degree of PCD was related to age and time in ICU. Duration of delirium was related to age, ICU time, and temperature on the third postoperative day. Thus, the findings supported the multiple factor theory for etiology of PCD. Certain factors interacted to produce PCD, while different factors interacted to prolong and intensify the delirium produced. PMID- 6913575 TI - Differences in types A and B behavior in response to acute myocardial infarction. PMID- 6913576 TI - Handholding: one means of transcending barriers of communication. PMID- 6913577 TI - The diagnosis of myocardial infarction in patients with permanent pacemakers. Part I. PMID- 6913578 TI - Differential methicillin susceptibilities of peptidoglycan syntheses in methicillin-resistant Staphylococcus aureus. AB - The mechanism of staphylococcal resistance to methicillin is unknown. Peptidoglycan synthesis was studied in a methicillin-resistant and a derived methicillin-sensitive Staphylococcus aureus strain. Although the methicillin minimum inhibitory concentration for growth of the methicillin-resistant strain was 1,600 micrograms/ml, peptidoglycan synthesis by the organism incubated in a wall synthesis solution was inhibited about 90% by 5 micrograms of methicillin per ml. In contrast, high concentrations of methicillin added to actively growing cultures of the methicillin-resistant strain had little effect on growth or peptidoglycan synthesis. Peptidoglycan synthesis in chloramphenicol-treated cultures was more susceptible to methicillin than it was in actively growing cultures of the methicillin-resistant strain. It is proposed that in this strain cell wall thickening peptidoglycan synthesis which predominates in cell wall synthesis solution and chloramphenicol-treated cultures is methicillin sensitive, whereas peptidoglycan synthesis involved in cell division, primarily in the region of the septum, which predominates in actively growing cultures is methicillin resistant. Both cell wall thickening and septal peptidoglycan syntheses are methicillin sensitive in the methicillin-sensitive strain. PMID- 6913579 TI - Studies on human high molecular weight (HMW) kininogen. III. Cleavage of HMW kininogen by the action of human salivary kallikrein. AB - Human high molecular weight (HMW) kininogen is a single chain with a molecular weight of 120,000 and is cleaved by plasma kallikrein sequentially into a nicked kininogen, an intermediate kinin-free protein (KFP-I), and a stable KFP-II. Here we report a study into the process of cleavage of human HMW kininogen by human salivary kallikrein. On incubation with salivary kallikrein, HMW kininogen was first converted into a nicked kininogen composed of disulfide-linked chains of 62,000 and 56,000 daltons. Subsequently, the nicked kininogen was cleaved into kinin and a KFP, which was apparently of equal size to the nicked kininogen, that is, KFP-I. In contrast to plasma kallikrein, salivary kallikrein did not cleave KFP-I into KFP-II. The two chains were separated by SP-Sephadex C-50 chromatography of reduced and alkylated KFP-I. The N-termini of HMW kininogen and the 62,000-daltons chain were found to be pyroglutamyl-isoleucyl, while that of the 56,000-daltons chain was found to be serine. These results indicate that the sequence of the two chains and kinin in human HMW kininogen is 62,000-daltons chain-kinin-56,000-daltons chain from the N-terminal end of HMW kininogen. Possible processes of cleavage of human HMW kininogen by human plasma and salivary kallikreins are also discussed. PMID- 6913581 TI - Identification of regulatory sequences contained in the 5'-flanking region of Drosophila lysine tRNA2 genes. AB - Transcription of Drosophila tRNA genes is controlled by signals within and outside the region coding for the mature tRNA. Deletion analysis has revealed an oligonucleotide sequence in the 5'-flanking region of a Drosophila tRNA2Lys gene to be responsible for the poor transcriptional activity of this and of other tRNA genes. The low template activity of this gene was maintained even after deletion of the 5'-flanking region up to nucleotide -23. Removal of nine additional nucleotides resulted in complete loss of transcriptional repression. The oligonucleotide responsible for transcriptional repression is GGCAGTTTTTG and is located 13 nucleotides upstream from the mature tRNA coding sequence. Since the sequence of the undecanucleotide is well conserved within the 5'-flanking region of all known Drosophila tRNA2Lys genes, we have investigated why the transcription of all these genes is not similarly repressed. Deletion or insertion of nucleotides between the mature tRNA coding region and this oligonucleotide resulted in tRNA genes with increased template activity. This observation suggests that the position of this oligonucleotide relative to some element downstream influences the extent of transcriptional repression. PMID- 6913580 TI - Selective inhibition of human leukocyte elastase and bovine alpha-chymotrypsin by novel heterocycles. AB - A number of N-arylbenzisothiazolinone 1,1-dioxides have been synthesized and examined for inhibitory activity against human leukocyte and porcine pancreatic elastase (EC 3.4.21.11), bovine alpha-chymotrypsin (EC 2.4.21.1), human leukocyte cathepsin G (EC 3.4.21.20), and bovine trypsin (EC 3.4.21.4). They are potent, selective, competitive inhibitors of human leukocyte elastase and chymotrypsin. The inhibitory capacity of these compounds is directly related to the electron withdrawing capability of the aryl substituents. When sufficiently activated, the amide bond in the heterocyclic ring can be cleaved by the enzyme, resulting in inhibition which is highly specific. The most potent inhibitor of hummotrypsin. The inhibitory capacity of these compounds is directly related to the electron withdrawing capability of the aryl substituents. When sufficiently activated, the amide bond in the heterocyclic ring can be cleaved by the enzyme, resulting in inhibition which is highly specific. The most potent inhibitor of human leukocyte elastase, the 2,4-dinitrophenyl derivative, has a Ki of 2.16 microM with elastase and 0.77 microM with chymotrypsin. This study demonstrates that it is possible to design specificity into non-peptide, low molecular weight serine protease inhibitors, which may have considerable pharmacologic potential. PMID- 6913582 TI - The composition of the nursing profession in South Africa in the mid-seventies and its implications for provision of health care. AB - An analysis of the composition of the nursing profession in South Africa reveals that the nurses were a heterogenous group with diverse dialects and cultures drawn from all social classes. Because of the unifying influence of the statutory control through the South African Nursing Council and the two official languages the nurses were organized into a strong and a stable profession. The predominant religion was Christianity, and the large majority of nurses were female, mainly young and married. The 116 189 member-strong profession was constituted by registered nurses, enrolled nurses, and nursing assistants. Although there was a variety of post-basic specialities for registered nurses there was still a good number of these nurses who were singly qualified, a certain portion who were doubly qualified and a minority who were triply qualified. A number of temporarily or permanently non-practising nurses constitute a reserve force to be relied on in a national emergency. This quantitative and qualitative state of the nursing profession had several implications for patient care. Some aspects reveal weak areas. The recommended remedial planning and re-organization arises from the obvious need and scope for improvement. PMID- 6913583 TI - The primary health care team: linked group discussion as a learning medium. PMID- 6913584 TI - 'Voices of concern'-a study of verbal communication about patients in a psychiatric day unit. AB - In this study, the author employs observations from a psychiatric day unit in an analysis of regularly occurring forms of 'professional talk'. Considerable staff time is scheduled for such talk, which must be considered as part of the health professional's work. Much of the talk which occurs may be analysed as having 'technical' significance in programming staff to behave appropriately towards different patients, so as to maximize the effectiveness of hospital treatment. Very much more time than is technically necessary, however, is devoted to talking about patients. Rather than seeing this 'superfluity' of talk as an indication of inefficiency within the system, the author examines its functions in maintaining the social structure of the unit and meeting the personal needs of the staff. This appears to be of particular importance against the background (common to many psychiatric settings) of staff-patient and interdisciplinary role ambiguity, high patient chronicity, and the absence of many of the structural and symbolic 'props' of a conventional hospital. This 'excess talk' is expensive in terms of professional time, and takes time away from direct patient contact. None the less, it may be a necessary cost if staff are to continue to pursue therapeutic goals within a deliberately 'informal' psychiatric setting. PMID- 6913585 TI - Adaptation problems with nursing home application for elderly persons: an application of the Roy adaptation nursing model. AB - This study sought to identify adaptation problems on the part of elderly persons and significant others that were associated with nursing home applications for elderly persons. Within the framework of the Roy Adaptation Nursing Model, an ex post facto research design was utilized to identify these adaptation problems. The four adaptive modes in this model are: physiological, self-concept, role function, and interdependence. The study group (n = 22) and a control group of elderly persons living in Calgary, as well as their significant others, were administered a structured questionnaire. Five hypotheses relating to overall adaptation problems, powerlessness, role reversal, guilt, and knowledge and utilization of services were formulated and tested. Only the hypothesis indicating role reversal on the part of the significant others was accepted. Adaptation problems encountered by the elderly which were associated with nursing home applications occurred in the self-concept and interdependence adaptive modes. The adaptation problems perceived by the significant others, which were associated with nursing home applications for their elderly, occurred in the self concept, role function, and interdependence modes. Adaptation problems from the significant others' perception rather than from the elderly persons' perception appear to be more significantly associated with nursing home applications. PMID- 6913586 TI - Negotiating the discharge of medical patients. PMID- 6913587 TI - The selection and organization of curricular experience in nursing. AB - Curriculum is the educational design of learning experiences for the students. Curricular experiences include course content as well as learning activities. The selection and organization of curricular experiences must also reflect the philosophy of the school. The identifying and organizing of curricular experiences begins with the analysis of curriculum objectives. The most commonly used approach in selecting learning experiences is the logical approach in which the process is treated as content in curriculum development. This paper attempts to analyse the selection and organization of the first year curricular experiences of the proposed curriculum by applying the logical approach. The proposed curriculum is designed for a 2-year diploma school of nursing. Nursing is offered as a continuum of increasing complexity throughout the three semesters of each year. The curricular framework is based on the health field concept; curricular experiences are selected and organized in accordance with this concept. Courses related to the four elements of the health field concept become mandatory classes for all students. Similarly clinical experience is organized so that a total integration of knowledge from these four elements is enhanced. The first year students study the general aspects of health and health field concept; the nursing process; helping relationships and selected skills necessary for meeting patient's physiological needs. The last semester of the first year is a synthesis practicum proposed to integrate principles and theories which the students have acquired previously and to apply them to the practice of nursing. PMID- 6913588 TI - Foreign nursing students in the USA: problems in their educational experiences. AB - With the increasing number of foreign nursing students enrolled in university nursing programmes in the United States and the paucity of relevant studies it would seem essential to assess the difficulties foreign nursing students encounter in their adjustment to university nursing programmes and to evaluate the mechanisms that facilitate their adaptation. Data from this study was based on the results of 82 questionnaires completed by foreign nursing students enrolled in university nursing programmes nationwide. Language difficulties, a faculty to a great extent unfamiliar with foreign cultures, rapid pace, insufficient clinical experience, and highly competitive programmes were found to cause the foreign nursing students problems in their educational experiences. In addition to identifying the difficulties foreign nursing students have in adjusting to a university nursing programme, this paper proposes and discusses changes that would help make the foreign nursing students' experiences more meaningful and effective. PMID- 6913589 TI - A critique of Bendall's So you passed, Nurse. PMID- 6913590 TI - Janforum: the reliability and validity of hospital accreditation in Australia. PMID- 6913591 TI - Regional centers: part I. A comparison of nursing responsibilities in level II and level III centers. PMID- 6913592 TI - Regional centers: part III. Three regions' educational efforts and infant mortality rates. PMID- 6913593 TI - The Utah test appraising mothers, revised. PMID- 6913594 TI - Summer 1979 at the birthplace, Gainesville, Florida. PMID- 6913595 TI - Regional centers: part II. The newborn transport system. PMID- 6913596 TI - Schizophrenia in pregnancy. PMID- 6913597 TI - The self-actualization of the certified nurse-midwife. PMID- 6913598 TI - The road to fatherhood: one man's personal remembrances. PMID- 6913599 TI - Back to school for the child on long-term hemodialysis. PMID- 6913600 TI - The Hemo Hotline. PMID- 6913601 TI - Patient factors in CAPD. PMID- 6913602 TI - Primary nursing: does it work in renal dialysis (RD) setting with end stage renal disease (ESRD) patients. PMID- 6913603 TI - Nursing participation in hemofiltration. PMID- 6913604 TI - Self dialysis training: analysis and critique of HCFA manual. PMID- 6913605 TI - Hemodialysis training in the home: a new experience. PMID- 6913606 TI - Portrait of a five year old on chronic hemodialysis. PMID- 6913607 TI - Purification from guinea pig erythrocyte stroma of a decay-accelerating factor for the classical c3 convertase, C4b,2a. AB - A protein with decay-accelerating activity for the classical C3 convertase, C4b2a, has been isolated on the basis of this function from guinea pig erythrocyte stroma. The isolation procedure for decay-accelerating factor of stroma (DAF-S) utilizes butanol extraction and chromatography on DEAE-Sephacel, hydroxylapatite, and phenyl Sepharose. Purified DAF-S has a m.w. of 60,000 and 65,000 on reduced and unreduced SDS gels, respectively, and exhibits m.w. of 30,000 and 175,000 on alkaline gradient gels, suggesting multiples of a 60,000 65,000 subunit. Purified DAF-S elicited a monospecific antiserum whose IgG fraction neutralized the decay-accelerating activity for C4b,2a affixed to 10(7) sheep erythrocytes (EAC1,4,2) in a dose-response fashion. The monospecific antiserum diluted up to 1:5120 agglutinated 1 x 10(6) guinea pig erythrocytes, but not sheep or human erythrocytes, suggesting that DAF-S, an integral membrane protein, has species-specific antigens that are expressed on the surface of the guinea pig erythrocyte. PMID- 6913608 TI - Inhibitory effect of C-reactive protein on alternative C pathway activation by liposomes and Streptococcus pneumoniae. AB - C-reactive protein (CRP) is an acute phase serum protein found associated with damaged tissue at sites of inflammation. CRP bound to multivalent phosphocholine containing or polycationic ligands activates C by the classical pathway. We have previously described liposomes of a particular lipid composition that are able both to activate the alternative pathway of C and to bind CRP. In addition many strains of Streptococcus pneumoniae activate the alternative pathway. We have shown CRP binding to these bacteria as well. Because antibody to an activating surface in many cases enhances alternative pathway activation, we tested CRP for a similar function in these systems. Our results indicate that, in contrast to antibody, CRP inhibits alternative pathway activation. This inhibition by CRP is apparently restricted to surfaces that bind CRP. Thus, CRP binding to membrane or bacterial surfaces can convert them from alternative pathway activation to classical pathway activation. PMID- 6913609 TI - Excretion of human urinary kallikrein quantity measured by a direct radioimmunoassay of human urinary kallikrein in patients with essential hypertension and secondary hypertensive diseases. AB - Recently, we established a very sensitive, specific and simple direct radioimmunoassay method for human urinary kallikrein. In this study, in order to clarify whether or not the low or high excretion rate of urinary kallikrein activity in patients with essential hypertension, primary aldosteronism, pheochromocytoma and Bartter's syndrome is caused by changes in enzyme quantity, urinary kallikrein excretion was measured with this direct radioimmunoassay method in normal subjects and in patients with these diseases. Urinary kallikrein excretion measured as enzyme quantity was significantly lower in patients with essential hypertension, and higher in patients with primary aldosteronism and Bartter's syndrome. These results are consistent with other previously reported data and our data measured by means of esterase assay or kininogenase assay. The results also suggest that lowered or elevated excretion of urinary kallikrein activity in these diseases is caused, in part at least, by the lowered or elevated excretion of enzyme quantity. PMID- 6913610 TI - Urinary Incontinence: New methods of diagnosis and treatment. PMID- 6913611 TI - Anxiety as a potential factor affecting maternal attachment. AB - Many factors may influence the initial mother-infant interactions. This exploratory study investigated the impact of one factor, anxiety, on maternal attachment in 30 married primigravidas. Observations of mother-infant interactions and scores from the Taylor Manifest Anxiety Scale were used. Results indicated that highly anxious mothers had low attachment scores. Mothers with high attachment scores had low anxiety ratings. In addition, affectionate behaviors were found to decrease as caretaking behaviors increased. PMID- 6913612 TI - Concerns of multiparas on the third postpartum day. AB - In order to ascertain the major concerns of multiparas and whether differences in their concerns vary according to variable factors (e.g., mother's age, education, socioeconomic status, infant's sex, feeding method, etc.), 56 multiparas in the Midwest were surveyed on their third postpartum day. A cord-sorting tool of 61 index cards was developed by the author for the study. Results showed that multiparas were not as concerned about themselves or their infants as about family relationships. Also, the greatest number of concerns were found in women 1) under 20 years old, 2) having one other child at home, and 3) delivering male infants. PMID- 6913613 TI - Contraception choices of female university students. PMID- 6913614 TI - Inconsistencies among nurses in breastfeeding knowledge and counseling. PMID- 6913615 TI - Organization and operation of a human breast milk bank. AB - Breast milk has replaced proprietary formulas as an important feeding for the premature and sick neonate. Over 30 milk banks have been established in the United States to provide breast milk to high-risk neonates. Planning a milk bank poses many problems as no uniform standards for quality control exist. A format for developing a breast milk bank and the protocol for donor screening, collection techniques, transport and storage of milk are presented. Rationale supporting each section of the protocol is also included. PMID- 6913616 TI - A conceptual framework of bonding. AB - Nurses involved in maternal-infant child care should objectively analyze any tools that purport to measure attachment and/or bonding. Has the author adequately defined the terms? Are directions given for making concepts operational for the practicing nurse? What are the foundations for placing values on parental behaviors? Do deviant parental behaviors reflect poor attachment or bonding, or are such behaviors merely indicative of limited parental opportunities for acquaintance? The presentation of of any conceptual framework should not be considered complete without empirical testing. Such testing and peer critique of a framework are essential fro any theory of bonding to evolve. With further research into the parental-child relationship, nurses can learn to provide adequate care for facilitating the bonding process in families. PMID- 6913617 TI - Genital Herpes: the need for counseling. PMID- 6913618 TI - Perinatal nursing education in Tennessee: a regional approach. PMID- 6913619 TI - A method to help new fathers develop parenting skills. AB - Interaction of parent and infant birth is important to the process of bonding and attachment. Much of this very early interaction is physical handling and care. New fathers may tend to feel uncomfortable and awkward with this handling due to lack of prior experience. A class was developed, in a private Midwestern hospital, to offer opportunities for fathers to gain knowledge, skill, and practice to make them feel more comfortable with this interaction and facilitate attachment. Response from participating fathers indicated that the classes were effective. PMID- 6913622 TI - [Restricting smoking habits during pregnancy]. PMID- 6913620 TI - NICU nursing care. PMID- 6913621 TI - Abortion is not a banner-waving issue. PMID- 6913623 TI - [St. Christopher's Hospice]. PMID- 6913624 TI - [Family participation in childbirths taking place at the Midwives' Institute]. PMID- 6913625 TI - [Giving birth on the terms of the baby and the family]. PMID- 6913626 TI - Nursing care plans--do we really need them? PMID- 6913627 TI - Alcoholism. PMID- 6913628 TI - Oral interview for selection of pre-service trainees. PMID- 6913629 TI - Opening speech to Coast Branch N.N.A.K. AGM on team work and nurses welfare. PMID- 6913630 TI - Nursing care planning. PMID- 6913631 TI - Leprosy. PMID- 6913632 TI - A mentally retarded child in a family. PMID- 6913633 TI - Epidural anaesthesia. Part II--The role of nurses and midwives in administration of epidural anaesthesia. PMID- 6913635 TI - [Current statistical file. Current trends in nurses and practical nurses]. PMID- 6913634 TI - Hospital drama: a new role for video? PMID- 6913636 TI - [The concept of Oriental medicine]. PMID- 6913637 TI - [Lessons in Oriental medicine: its application in nursing]. PMID- 6913638 TI - [Lessons in Oriental medicine: a holistic approach in therapy]. PMID- 6913639 TI - [Thoughts on the teaching method in adult nursing: a keypoint in instruction in clinical training]. PMID- 6913640 TI - [History of logic of Oriental medicine]. PMID- 6913642 TI - [Life among farmers engaged in land development projects (2). A personal history of a public health nurse]. PMID- 6913641 TI - [Post-graduate nursing education in specialized areas--an impression on the first seminar on rehabilitation of patients with stomas]. PMID- 6913643 TI - [Profile of a nurse: Ms. Ayako Yamaguchi who is active in the Association of Nursing Psychodrama and studying the practical application of the theory to nursing structure in human relations]. PMID- 6913644 TI - [Medical topics: polyneuritis caused by cooking oil. 5]. PMID- 6913645 TI - [Medical topics: coffee and chronic mastitis]. PMID- 6913646 TI - [Diary of a home visiting nurse: patients with chronic respiratory insufficiency and the rain]. PMID- 6913648 TI - [Doctoral education in nursing in the United States--the courses and its needs]. PMID- 6913647 TI - [Iatrogenic incidents involving nursing. 5. An incident relating to therapeutic actions: postoperative observation and the response of the nurse]. PMID- 6913649 TI - [Current statistical file. On nursing-related statistical data]. PMID- 6913650 TI - [25 books selected by nurses]. PMID- 6913651 TI - [Reading and the nurse]. PMID- 6913652 TI - [Nurses and reading. Discussion]. PMID- 6913653 TI - [Library resources for nurses--with special reference to management of information as a support of "practical science" and availability of the reference materials]. PMID- 6913654 TI - [Iatrogenic incidents concerning nursing. 6. Suicides and violence resulting in injuries at psychiatric institutions--examples in which negligence was ruled out]. PMID- 6913655 TI - [Nursing in the European Community]. PMID- 6913656 TI - [Life among farmers engaged in land development projects. (3) A personal history of a public health nurse]. PMID- 6913657 TI - [Profile of a nurse. Ms. Keiko Fukuda, a midwife active in regional maternal and infant health care activities]. PMID- 6913658 TI - [Medical topics. Phenylketonuria and alcohol drinking]. PMID- 6913659 TI - [Medical topics. Delayed puberty]. PMID- 6913660 TI - [Medical topics. Therapeutic embolization]. PMID- 6913661 TI - [Diary of a home visiting nurse. 2. Grief of a man whose wife is undergoing hemodialysis]. PMID- 6913663 TI - [A profile of a nurse. Ms. Mitsuko Hasegawa, the author of a study on the expenses of hospitalization]. PMID- 6913662 TI - [Life among farmers engaged in land development projects. 4. A personal history of a public health nurse]. PMID- 6913664 TI - [Medical topics. Smoking and the spermatozoa]. PMID- 6913666 TI - [Medical topics. Complement]. PMID- 6913665 TI - [Medical topics. The thyroid function and breast cancer]. PMID- 6913667 TI - [A diary of a home visiting nurse. 3. Home care of a patient in the terminal stage of lung cancer]. PMID- 6913668 TI - [Iatrogenic incidents involving nursing. 7. Nursing-related incidents at psychiatric hospitals]. PMID- 6913669 TI - [Nursing in the European Community]. PMID- 6913671 TI - [1981 General Assembly of the Japanese Nursing Association: the public health nursing section]. PMID- 6913670 TI - [Current statistical files. The age composition of active nursing manpower]. PMID- 6913672 TI - [1981 General Assembly of the Japanese Nursing Association: the midwifery section]. PMID- 6913673 TI - [1981 General Assembly of the Japanese Nursing Association: the nursing section]. PMID- 6913674 TI - [Graduates of non-nursing universities and junior colleges entering nursing schools and their problems]. PMID- 6913675 TI - Associate degree nursing in Kansas. PMID- 6913676 TI - Writing for publication: an art and science or helpful hints for the budding author. PMID- 6913677 TI - Responsible for patients, not tasks -- the joy of "modular' nursing at St. Francis. PMID- 6913679 TI - [Social and economic welfare]. PMID- 6913678 TI - Nursing Education at Mid-America Nazarene College. PMID- 6913680 TI - Panel discussion by the KNA: partners in education-teachers and students. Opening address. PMID- 6913681 TI - Panel discussion by the KNA: partners in education-teachers and students. Introduction. PMID- 6913682 TI - Panel discussion by the KNA: partners in education-teachers and students. Philosophical stances for future nursing education. PMID- 6913683 TI - Panel discussion by the KNA: partners in education-teachers and students. Roles and preparation for the future nurse-educators. PMID- 6913684 TI - Panel discussion by the KNA: partners in education-teachers and students. Preparation of students for future challenge. PMID- 6913685 TI - [Report of the 3d joint seminar of KNA & KNA of America]. PMID- 6913686 TI - [Biculturalism in nursing. Reality shock]. PMID- 6913687 TI - [Biculturalism in nursing. Cultural shock]. PMID- 6913688 TI - [Biculturalism in nursing. Dualism of nursing education and nursing in Korea]. PMID- 6913689 TI - [Report by the formal representatives about the 17th Congress of the ICN]. PMID- 6913690 TI - [Research presentation: job satisfaction of the Korean nurses in the United States]. PMID- 6913691 TI - [A study of infant mortality rate in Korean rural areas]. PMID- 6913693 TI - SNP responds to research article: "School nurse practitioners analysis of questionnaire and time/motion data". PMID- 6913692 TI - On students' privacy. PMID- 6913694 TI - Multidisciplinary assessment of learning problems - school nurse's role. PMID- 6913696 TI - Helping ninth-graders make responsible health decisions. PMID- 6913695 TI - Preparing health educators to teach mental health. PMID- 6913697 TI - Health education... a separate and unique discipline. PMID- 6913698 TI - Consent and confidentiality: legal issues in adolescent health care for the school nurse. PMID- 6913700 TI - Nurse's station: the effectiveness of school nurse practitioners: a review of the literature. PMID- 6913699 TI - The Minnesota smoking prevention program: a seventh-grade health curriculum supplement. AB - A seventh-grade program based on social psychological theories attempted to prevent non-smokers from starting to smoke. Two competing strategies, a Short Term Influences Curriculum and a Long-Term Influences Curriculum were compared. Within these broad strategies, several other variables were also tested: the use of same age peer opinion leaders or health educators as teachers, the use of media supplements and the elicitation of a public commitment not to become a regular smoker. Program effectiveness was evaluated using self-report measures confirmed by saliva thiocyanate analyses. The treatment groups were compared to a standard curriculum comparison group. PMID- 6913701 TI - Health educator's notebook: proclaiming sexuality education. PMID- 6913703 TI - [The state examination for nurses and nursing education: a discussion]. PMID- 6913702 TI - Screening of anti-progestins using in vitro human uterine progesterone receptor assay system. PMID- 6913704 TI - [State examination for nurses and nursing education - a clinical viewpoint]. PMID- 6913705 TI - [Trends in the questions posed at the state examination for nurses]. PMID- 6913706 TI - [Licensing examination for registered nurses and extension of nursing duties]. PMID- 6913708 TI - [Bedside conference: planning of clinical training. (7). The respiratory system: lung cancer (1)]. PMID- 6913707 TI - [Adaptation in the daily activities of patients with colostomy following discharge from hospital and associated problems]. PMID- 6913709 TI - [Leadership within an organization - various types of leadership in industries]. PMID- 6913710 TI - [Nursing education [3]. On nursing instructors (1)]. PMID- 6913711 TI - [The administrative component of the nurse administrator's role]. PMID- 6913713 TI - [Overnight stays of inpatients: the significance and associated problems - the current medical status and problems]. PMID- 6913712 TI - [Attitudes and behaviors of nursing students in the interaction with patients - through an evaluation of the process record]. PMID- 6913714 TI - [Overnight stays of inpatients. Overnight stays and independence of patients]. PMID- 6913715 TI - [Overnight stays of inpatients. Overnight stays during the rehabilitation process]. PMID- 6913716 TI - [Overnight stays of inpatients. Significance of overnight stays by patients with poor prognosis]. PMID- 6913717 TI - [Overnight stays of inpatients. Overnight stays of pediatric patients and their lives in the hospital]. PMID- 6913719 TI - [Human science: religion (5). Factors outside the human psychosomatic realm - human observation in logo-therapy]. PMID- 6913718 TI - [Health care within families - evaluation of emergency care]. PMID- 6913720 TI - [Bedside conference: planning of clinical training (8). The respiratory system: lung cancer (2)]. PMID- 6913721 TI - [Interpersonal relationship and leadership in therapeutic scenes]. PMID- 6913722 TI - [Nursing education (4). On nursing instructors (2)]. PMID- 6913723 TI - [Significance of Roy's nursing theory in Japanese nursing education]. PMID- 6913724 TI - [Interpretation of Roy's "Nursing Theory". A discussion]. PMID- 6913725 TI - [Nursing research useful in clinical practice and education: prevention of decubitus ulcer. The relationship between clinical practice, education, and research in nursing]. PMID- 6913726 TI - [Nursing research useful in clinical practice and education: prevention of decubitus ulcer. The current status and future questions on the research on nursing concerning prevention of decubitus ulcer]. PMID- 6913727 TI - [Nursing research useful in clinical practice and education: prevention of decubitus ulcer. Nursing study in clinical practice - its relationship to the practice observed in a case study on decubitus ulcer]. PMID- 6913728 TI - [Nursing research useful in clinical practice and education: prevention of decubitus ulcer. Instructions on prevention of decubitus ulcer in basic education]. PMID- 6913729 TI - [Nursing research useful in clinical practice and education: prevention of decubitus ulcer. Nursing study in daily activities - in clinical practice and education]. PMID- 6913730 TI - [Human science. Religion (6). A common denominator of medicine and religion]. PMID- 6913731 TI - [Bedside conference. Planning a clinical training (9). Hematology (1)]. PMID- 6913732 TI - [Nursing administration and leadership]. PMID- 6913733 TI - [On nursing education (5). A focus on clinical training (1)]. PMID- 6913734 TI - [Results of clinical training in an operating room: an observation through the clinical training record]. PMID- 6913735 TI - [In search of more effective interactions with students striving for self development as nursing personnel]. PMID- 6913736 TI - Trends in National Labor Relations Board decisions for the health care delivery. PMID- 6913737 TI - Nursing ethics, physician ethics, and medical ethics. PMID- 6913738 TI - Notions of teams and team talk in health care: implications for responsibilities. PMID- 6913739 TI - The parents view of the role of the paraprofessional. PMID- 6913740 TI - Hospitalisation of infants and pre-schoolers. Observations and reflections by a live-in mother. PMID- 6913742 TI - The primary care nurse practitioner: development of this role in the United States. PMID- 6913741 TI - Sexism by nurses. PMID- 6913743 TI - Migrants in Australia: problems faced by-/across lingual and cultural barriers. PMID- 6913744 TI - Nursing at the crossroads. PMID- 6913745 TI - Living with epidermolysis bullosa. PMID- 6913746 TI - Aboriginal infant mortality. PMID- 6913747 TI - [Differential diagnosis between food toxico-infections (salmonelloses) and acute surgical and therapeutic diseases]. PMID- 6913748 TI - [Use of trilene and sombrevin anesthesia in minor gynecologic operations]. PMID- 6913749 TI - [Treatment methods in nicotinism]. PMID- 6913750 TI - [Physiotherapy of periodontosis]. PMID- 6913751 TI - [Therapeutic use of potable mineral waters]. PMID- 6913752 TI - [Self massage]. PMID- 6913753 TI - [Apparatus for releasing oxygen foam]. PMID- 6913754 TI - [Physical development of newborn infants in the North]. PMID- 6913755 TI - [Premature infant. 2. Physical and neuropsychic development characteristics of premature infants during the 1st year of life]. PMID- 6913756 TI - [Prevention of premature senility]. PMID- 6913757 TI - [Grains of experience]. PMID- 6913758 TI - [Physical development of preschool children in polar regions]. PMID- 6913759 TI - [Ideological educational work in a hospital therapeutics ward]. PMID- 6913760 TI - [Allergy]. PMID- 6913761 TI - [Basic principles in rehabilitating heart surgery patients]. PMID- 6913762 TI - [Hyperbaric oxygenation in clinical practices]. PMID- 6913763 TI - [Functional treatment of spinal fractures without injury to the spinal cord]. PMID- 6913764 TI - [Organization of the early detection and treatment of coxofemoral joint dysplasia and congenital hip dislocation]. PMID- 6913765 TI - [Nurse's work in the urology office]. PMID- 6913766 TI - [Clinical aspects and treatment of paronychia]. PMID- 6913767 TI - [Metallic osteosynthesis of open fractures of the metacarpal bones and finger phalanges]. PMID- 6913768 TI - [Machine massage]. PMID- 6913769 TI - [Combined treatment of complicated forms of facial furunculi and carbuncles]. PMID- 6913770 TI - [Postinjection abcesses and phlegmons]. PMID- 6913771 TI - [Work organization in a burn ward dressing room]. PMID- 6913772 TI - [Most typical infractions of the rules for asepsis and antisepsis in nurses' work with drug injections]. PMID- 6913773 TI - [Needle holder for prolonged intravenous transfusions]. PMID- 6913774 TI - [Device made of polyethylene film for conserving a pervomur solution]. PMID- 6913775 TI - [Handling of pressure bags used postoperatively]. PMID- 6913776 TI - [Premature infant: problems of care, nutrition and raising. 1. The anatomicophysiological characteristics of premature infants]. PMID- 6913777 TI - [Physical methods of treating psoriasis]. PMID- 6913778 TI - Division of gerontological nursing practice Mini-White House Conference Community Forum. PMID- 6913779 TI - Nursing targeted in legislation. PMID- 6913780 TI - Cross-cultural nursing with Michigan migrant workers. PMID- 6913781 TI - A midwifery clinical teaching course. PMID- 6913782 TI - Nature's sounder judgement. PMID- 6913783 TI - Ethical conflicts in obstetrics - the other point of view. PMID- 6913784 TI - Hazards in health care: DHSS hazard notification system. PMID- 6913785 TI - Operating theatres--a national picture of provision and utilisation. PMID- 6913786 TI - Management of the operating department in the reorganised health service-No. 7. PMID- 6913787 TI - The role of the nursing officer responsible for the operating department-No. 6. PMID- 6913788 TI - Quo vadis, anaesthetic nurse. PMID- 6913789 TI - The total care of a patient within the operating department. PMID- 6913790 TI - The history and development of the arthroscope. PMID- 6913791 TI - Importance of cardiac cell membranes in vanadate-induced NADH oxidation. PMID- 6913793 TI - The benefits, risks, and complications of dental treatment for the ESRD patient. PMID- 6913792 TI - [Variability of the electrical activity of Helix pomatia neuron PPa1]. AB - Transitions of electrical activity were investigated in the PPa1 bursting neuron of the snail Helix pomatia. This neuron was found to exhibit the following modes of the activity: silent, beating, low amplitude and high amplitude bursting ones. The transitions between different modes of electrical activity occur within several hundreds of seconds. Such transitions were demonstrated to be simultaneous with changes in the membrane potential of other neurons. Application of a water-soluble fraction of the snail brain to the neuron evoked transitions of electrical activity similar to those occurring spontaneously. The analysis of the data obtained leads to the hypothesis that the activity of the PPa1 neuron is not of endogenous nature but is due to the action of substances released by other neurons. PMID- 6913795 TI - Contractural mutual fund plans offer nursing professionals productive investment choice. PMID- 6913794 TI - Hydrocele: a complication of CAPD. PMID- 6913797 TI - An open letter to hospital employees. PMID- 6913796 TI - Senate oversight hearings. PMID- 6913798 TI - Nutrition notes. PMID- 6913799 TI - Clinical excellence. PMID- 6913800 TI - On the scene: University of Rochester Medical Center. PMID- 6913801 TI - Unification model of nursing at the University of Rochester. PMID- 6913802 TI - The primary care nurse clinician: link between patient and system. PMID- 6913803 TI - The role of the acute care nurse practitioner in cardiac surgery. PMID- 6913804 TI - Continuity of care between hospital and home. PMID- 6913805 TI - Toward clinical excellence in nursing: a program for development of nurses. PMID- 6913806 TI - Staff nurse involvement in program implementation: a direct outcome of the unification model. PMID- 6913807 TI - Development of a clinical nursing advancement system. PMID- 6913808 TI - Nursing education under the unification model. PMID- 6913809 TI - A student contribution to excellence in the unification model. PMID- 6913810 TI - On the scene: University of Rochester Medical Center. Interdisciplinary group meetings. PMID- 6913811 TI - Nursing leadership for clinical excellence: balancing differentiation requirements. PMID- 6913812 TI - Extending the influence of the clinical nurse specialist. PMID- 6913814 TI - The clinical nurse specialist as consultant. PMID- 6913813 TI - Clinical advancement. PMID- 6913815 TI - The clinical nurse specialist in a private medical practice. PMID- 6913816 TI - NAQ legal forum: restrictions on male nurse employment in obstetric care. PMID- 6913817 TI - Leadership and clinical excellence in interdisciplinary settings. PMID- 6913818 TI - Sharing: when I was busy "being nobody". PMID- 6913819 TI - Prostatic cancer. PMID- 6913820 TI - Medication errors: don't abbreviate daily. PMID- 6913821 TI - Managing flail chest: a matter of maintaining breath...and life. PMID- 6913822 TI - Prepare your unit to manage a code with a mock-emergency exercise. PMID- 6913823 TI - Challenge: Margie's shins--what's wrong with them? PMID- 6913824 TI - The treadmill stress test: coaching your cardiac patient along the path to recovery. PMID- 6913826 TI - When the anorectic patient challenges you... PMID- 6913825 TI - Mrs. Hill needed more than caring..and more than a care plan. PMID- 6913827 TI - Inside anorexia. PMID- 6913828 TI - Reducing discharge planning paperwork with a pocket-size discharge planning record. PMID- 6913829 TI - What patients can teach you about your patient teaching. PMID- 6913830 TI - Expect the unexpected when you care for a dying patient. PMID- 6913831 TI - Drawing blood from a Hickman catheter. PMID- 6913832 TI - Dealing with the patient's denial--what should you do? PMID- 6913833 TI - What to say...and do...when your patient asks about CT scans. PMID- 6913834 TI - Test your knowledge of postoperative nursing care. PMID- 6913835 TI - Lawyer on call: no written order for no code. PMID- 6913836 TI - Consultation: minimizing radiation exposure. PMID- 6913837 TI - You've joined the management team? PMID- 6913838 TI - Effective communication techniques. PMID- 6913839 TI - Art and science of management: the uses of power. PMID- 6913840 TI - A staff nurse's guide to leadership. PMID- 6913841 TI - Breaking the chain of infection. PMID- 6913842 TI - Closing the audit cycle. PMID- 6913843 TI - Outcome charting. PMID- 6913845 TI - Law for the nurse manager: violation of dress code. PMID- 6913844 TI - Parenting aspects of nursing supervision. PMID- 6913846 TI - Professionalizing assignments. PMID- 6913848 TI - When is inservice appropriate? PMID- 6913847 TI - Performance appraisal of CCU nurses. PMID- 6913849 TI - Focus: on a counselor for nurses. PMID- 6913850 TI - Perspectives in nursing: fighting for funds for adequate staffing. PMID- 6913851 TI - Honesty, incident reports and risk management. PMID- 6913852 TI - How much should you be paid? PMID- 6913853 TI - Safety. Hearing protection: who needs training? PMID- 6913854 TI - Working with beryllium. PMID- 6913855 TI - Stress: introducing the nursing process. PMID- 6913856 TI - Malpractice insurance. PMID- 6913857 TI - Immunizations. V. PMID- 6913858 TI - Inhibition of Na+ reabsorption in the rat parotid gland by prostaglandin E1 and kallidin: implications for cystic fibrosis. AB - Prostaglandin E1 caused a dose-related inhibition of sodium reabsorption in the rat parotid gland when injected by retrograde perfusion into the glandular ducts. The extent of inhibition ranged from 11.7 +/- 2.4% at a dose of 2.5 micrograms to 63.8 +/- 8.9% at a dose of 31.2 micrograms. Both phospholipase A2, an enzyme involved in prostaglandin synthesis, and arachidonic acid, a precursor of prostaglandins, also increased the Na+ concentration of parotid saliva in a dose dependent fashion. With phospholipase A2 the inhibition ranged from 21.6 +/- 4.4% at a dose of 3 micrograms to 73.5 +/- 8.2% at a dose of 30 micrograms. With arachidonic acid, the degree of inhibition was 5.1 +/- 3.0% at a 10(-5) M dose and 57.7 +/- 10.2% at a dose of 10(-3) M. Lysine bradykinin (kallidin), a peptide present in salivary and other exocrine glands and their secretions, also caused a 30% inhibition of Na+ reabsorption when retroperfused at a concentration of 12.5 micrograms, as did kallikrein (176 micrograms) and trypsin (33.3 micrograms). These results indicate that prostaglandins and kinins can inhibit Na+ reabsorption in the rat parotid duct when present in the luminal side of the cells. Since they are normally present in exocrine glands and can presumably be secreted, they may have a role as luminal factors in the regulation of transductal transport of Na+. The possibility that they may be increased in the exocrine secretions of patients with cystic fibrosis and that they may act as the so-called cystic fibrosis "factors" is also raised by the findings of this study. PMID- 6913859 TI - Beginning resolution of the oedipal conflict in a lesbian about to become a "parent" to a son. PMID- 6913860 TI - Privacy: belonging to oneself. PMID- 6913861 TI - The image of psychiatric nurses in motion pictures. PMID- 6913862 TI - Psychiatric nursing at the crossroads: quo vadis. PMID- 6913864 TI - The nucleotide sequence of the tRNAMMet from the archaebacterium Thermoplasma acidophilum. AB - Using in vitro labelling techniques, a tRNAMMet from Thermoplasma acidophilum, a member of the Archaebacteriae, has been shown to have the sequence: pGCCGGG Gs4UGGCUCANCUGGAGGAGC m2(2)GCCGGACmUCAUt6AAUCCGGAGGUCUCGGG psi psi CmGAUCCCCGAUCCCGGCACCAOH. Despite the small genome size of this non-parasitic organism, eight modified nucleosides are present, one of which is typically eubacterial, one of which is typically eukaryotic and some of which appear to be unique to the archaebacteria. There is no close sequence homology between this tRNA and that of any other methionine tRNA so far sequenced (less than 70%) but it has almost 90% homology with the nucleotide sequence proposed by Eigen and Oswatitsch for the ancestral quasi-species. PMID- 6913863 TI - The nucleotide sequence of the large ribosomal RNA gene and the adjacent tRNA genes from rat mitochondria. AB - We have sequenced the Eco R(1) fragment D from rat mitochondrial DNA. It contains one third of the tRNA (Val) gene (the remaining part has been sequenced from the 3' end of the Eco R(1) fragment A) the complete gene for the large mt 16S rRNA, the tRNA (Leu) gene and the 5' end of an unidentified reading frame. The mt gene for the large rRNA from rat has been aligned with the homologous genes from mouse and human using graphic computer programs. Hypervariable regions at the center of the molecule and highly conserved regions toward the 3' end have been detected. The mt gene for tRNA Leu is of the conventional type and its primary structure is highly conserved among mammals. The mt gene for tRNA(Val) shows characteristics similar to those of other mt tRNA genes but the degree of homology is lower. Comparative studies confirm that AGA and AGG are read as stop codons in mammalian mitochondria. PMID- 6913866 TI - Continuing controversy. PMID- 6913865 TI - Continuing controversy. PMID- 6913869 TI - A student's perspective on the doctoral dilemma. PMID- 6913867 TI - Anger: an alienating communication hazard for nurses. AB - In summary, the following information seems to be available to us. We know how alienation occurs generally; that nurses do report becoming alienated and behave as if they were alienated; and that alienation tends to be activated for nurses in the presence of three communicative variable--facts, feelings, and force, as described above. While further research is needed, the investigations that have already been carried out strongly suggest a need for planned intervention to help nurses deal with communications, particularly angry or critical ones, from supervisors and others in some way other than by withdrawing into alienation. Some preliminary attempts have been made in this direction, but describing these is not within the scope of this article. Nurses and their superordinate colleagues might well ponder interventions of their own, however; the chronic problems of turnover and shortage would appear too important to leave to the examination of individual researchers. After all, it is practicing nurses at all levels who both need to resolve these problems and have any chance of doing so. PMID- 6913868 TI - Doctoral education in, of, and for nursing: an historical analysis. PMID- 6913870 TI - Faculty practice--noble intentions gone awry? PMID- 6913871 TI - Assessing the adequacy of clinical learning settings. PMID- 6913872 TI - The interpersonal dimension of collegiality. PMID- 6913873 TI - Moving into the Second Stage: an interview with Betty Friedan. PMID- 6913874 TI - Quality assurance: an educational approach. PMID- 6913876 TI - Self-concept and health beliefs in compliant and noncompliant hypertensive patients. PMID- 6913877 TI - Financial incentive and labor supply of married professional nurses. PMID- 6913875 TI - End paper: what if... ? PMID- 6913878 TI - Young children's ability to conserve facial identity when facial emotion varies. AB - Children, ages three to five, judged which of three photographs of unfamiliar adult female faces was a picture of the same person shown in a target photograph. The three photographs depicted facial expressions of negative emotion, and the target photographs depicted negative or positive emotion. Children performed above chance levels at age three years (p less than .0001), and accuracy increased significantly with age (p less than .0001) from 50 percent at age three to 83 percent at age five. The three-year-olds were significantly less accurate than either older group (p less than .05), but the four- and five-year-olds did not differ. Optimal performance scores from the present study and a previous study (Gorman, 1978) showed that no child achieved mastery at age three; approximately one-third of the children demonstrated mastery at age four; a rapid rise in mastery was seen around age five or older; and the full cohort demonstrated mastery by age seven. Error patterns for three-year-olds were based on mouth configuration cues, and for five-year-olds on emotion similarity. PMID- 6913879 TI - Anxiety and complications in patients on hemodialysis. AB - Approximately 175 patients at a dialysis unit were screened for entrance into the study; 43 patients were accepted according to the research criteria. These 43 subjects were given the trait anxiety test from the State-Trait Anxiety Inventory by Spielberger, Gorsuch, and Lushene (1968). Subsequently, the subjects with the ten lowest and ten highest scores were followed over two months or a total of 454 dialyses, and observed for hospitalizations, clinic appointments for treatment, and deaths. During dialysis they were observed for: hypotension; nausea and vomiting; fluid overload; infection of vascular access; clotting of vascular access; epistaxis; pain; pruritus; muscle cramps; and headache. The low anxiety group was found to have a significantly greater incidence of hypotension while the high anxiety group had a greater incidence of clinic appointments for treatment, fluid overload, and cramps. The latter group also had a significantly greater incidence of total complications with the exception of hypotension. Implications were made that appropriate nursing intervention might help prevent physical discomforts in patients on hemodialysis. PMID- 6913880 TI - Maternal compliance in immunization of preschoolers as related to health locus of control, health value, and perceived vulnerability. AB - The health attitudes and behaviors of 94 mothers of preschool children were investigated by personal interview in this descriptive correlational study. Mothers were divided into two groups, depending on their compliance or noncompliance, with recommended immunizations for their children. Subjects were assessed for health locus of control, perceived vulnerability to six communicable diseases, and health as a value. Demographic variables of age, education, religion, ethnicity, income, and recall of earlier poliomyelitis epidemics were studied. Analysis of variance, chi-square and descriptive statistics were used in the data analysis. Results revealed no significant differences between compliant and noncompliant mothers to health locus of control measure, perceived vulnerability to six diseases under study, or recollection of earlier poliomyelitis epidemics. The majority of mothers were Hispanic, Catholic, in their late twenties, of low income and with a 12th grade education or less. Health as a value was selected first or second by the subjects in most cases, regardless of immunization compliance behavior. Compared with a normative sample, mothers in this study were predominantly more external than internal in their locus of control orientation. PMID- 6913881 TI - Maternal response to their chronically ill infants' attachment behavior of crying. AB - Six chronically ill infants and their mothers were observed in their homes over a three-month period. During this study 388 infant crying bouts and maternal response episodes were analyzed, and compared to the behaviors of a literature control group of 26 well infants and their mothers. Results indicated there are differences between the crying patterns of ill and well infants. Maternal response patterns to ill infant crying seemed to be determined by characteristics of the infant's cry rather than by specific infant characteristics (sex, ordinal position, degree of illness). Implications for maternal-ill infant interaction and implications for nursing practice are discussed. PMID- 6913882 TI - Attitudinal correlates of employee theft of drugs and hospital supplies among nursing personnel. PMID- 6913883 TI - Bereavement crisis intervention for widows in grief and mourning. PMID- 6913884 TI - Health impact of a nurse midwife program. PMID- 6913885 TI - The grounded theory approach in nursing research. PMID- 6913886 TI - A practical guide to political effectiveness. The case of federal funding for nursing research. AB - The future viability of nursing research depends on federal funding decisions, which in turn depend upon national and local action by researchers and other advocates of nursing research. Since successful action is facilitated by familiarity with national policy-making, the legislative process is reviewed and a plan for action at the state and local level is offered. Basic actions are suggested to organize, arouse public support, build coalitions, and gain access to legislators. All these must follow a developed work plan. Ideas for specific implementing steps are provided, but each local area requires specially designed activities appropriate for their own needs and resources. The goal is to build a grass roots system to support national lobbying to stabilize and increase federal funding for nursing research. PMID- 6913887 TI - Publishing cooperative research. PMID- 6913888 TI - Nurses, physicians, and pharmacists: their knowledge of hazards of medications. AB - At a major tertiary care teaching hospital, random samples of 100 nurses, 102 physicians, and all of the hospital's 14 pharmacists were tested on their knowledge of the hazards of medications. The 25-question examination was generated by way of a rigorous validating procedure and was self-administered by the practitioners. Based on a perfect examination score of 100, the group mean scores of the nurses, physicians, and pharmacists were 72.3, 81.3 and 85.1, respectively. A one-way analysis of variance demonstrated that the difference in knowledge among the three groups of practitioners was significant (p less than .001). Pairwise (Scheffe) contrast tests revealed that the difference in knowledge between the physicians and nurses, and the pharmacists and nurses was significant; the nurses proved to be the least knowledgeable of the three practitioner groups. The nurses' scores were analyzed by years of nursing experience, type of educational preparation, hospital service affiliation, and hospital shift. A one-way analysis of variance revealed that there was a significant difference in nurses: knowledge by hospital shift (p less than .05). A posteriori contrast tests (Scheffe) indicated that the group mean score of the day shift nurses (mean = 75.6) was significantly different than the average of the evening and night shift nurses' scores (mean = 69.9). PMID- 6913890 TI - The National Research Service Awards with emphasis on the mentor relationship. PMID- 6913889 TI - Relationship between an ascending musical stimulus program and activity levels of hyperactive children: a pilot study. PMID- 6913891 TI - Pre-operative teaching. PMID- 6913892 TI - Theatre? Why not! PMID- 6913893 TI - A pressure sore survey. PMID- 6913894 TI - Discrepancies in the perceptions of a structural relationship for teamwork--2. PMID- 6913895 TI - The nurse and the patient: communication skills. Getting it across (information giving--part 2). PMID- 6913897 TI - 'It is the real test of a nurse whether she can nurse a sick infant'. PMID- 6913896 TI - Insight through images. PMID- 6913898 TI - The criteria for brain death in England-1. PMID- 6913899 TI - Nursing care study: subacute bacterial endocarditis. PMID- 6913901 TI - The physiology of penicillin. PMID- 6913902 TI - Mr. Migraine. Interview by Laurence Dopson. PMID- 6913903 TI - The bridgebuilders' guide--6. Teaching and learning, insight and growth. PMID- 6913900 TI - Nursing agencies: their value in reducing costs. PMID- 6913904 TI - A lady with a 60% burn. PMID- 6913905 TI - Profits from pain. PMID- 6913906 TI - Nursing care study: abdominoperineal excision of rectum. PMID- 6913907 TI - A shift of emphasis some thoughts of nurses' duty rotas. PMID- 6913908 TI - Dementia as an experience. PMID- 6913909 TI - First night. PMID- 6913911 TI - Getting away from it all? PMID- 6913910 TI - The generation game. PMID- 6913912 TI - Systems of life No 82. Systems and signs: reproductive system - 3. Female (contd). PMID- 6913913 TI - Community nurses and health care recording. PMID- 6913914 TI - Help for health. PMID- 6913915 TI - Ward planning at the crossroads. PMID- 6913916 TI - What Katie did next. PMID- 6913917 TI - Children in hospital - 1. Preparation of parents and their children for a planned hospital admission. PMID- 6913918 TI - Protracted dying: a challenge to the caring team. PMID- 6913919 TI - The post-prostatectomy patient. PMID- 6913921 TI - What is occupational therapy? PMID- 6913920 TI - Contraception--a woman's dilemma. PMID- 6913922 TI - Taking refuge. PMID- 6913924 TI - Child psychiatry. 2. Conduct difficulty. PMID- 6913923 TI - Child psychiatry. 1. Troublesome behaviour. PMID- 6913925 TI - Child psychiatry. 3. The hyperactive child. PMID- 6913926 TI - Child psychiatry. 4. The Children's Committee. PMID- 6913928 TI - In the short term.. Interview by Laurence Dopson. PMID- 6913929 TI - Nurse--do you care enough? PMID- 6913927 TI - Branching out. PMID- 6913931 TI - Nursing care study: dying with dignity. PMID- 6913930 TI - Security: a nursing responsibility? PMID- 6913932 TI - Children in hospital-2. How parents feel. PMID- 6913933 TI - I'm sorry, I did not hear what you said. PMID- 6913934 TI - Living on a knife edge. PMID- 6913936 TI - In-service training. PMID- 6913935 TI - Entrance to nurse training by O levels and the GNC 'E' test. PMID- 6913937 TI - Providing care. PMID- 6913939 TI - Nursing care study: did I help her? PMID- 6913938 TI - Fetal alcohol syndrome--the American scene. PMID- 6913940 TI - Intermittent peritoneal dialysis. PMID- 6913942 TI - Children in hospital--3. 'I fell awful--where's my mummy?'. PMID- 6913941 TI - Fire! The nursing response. PMID- 6913943 TI - Male nurses in midwifery. PMID- 6913944 TI - Care and teaching of patients with glaucoma. PMID- 6913945 TI - Cataracts and intraocular lenses: from cloudy to clear. PMID- 6913946 TI - Retinal vascular disorders: nursing and medical implications. PMID- 6913947 TI - Retinal detachment and vitrectomy: nursing care. PMID- 6913948 TI - Common visual disorders in children. PMID- 6913949 TI - Pathophysiology of chronic renal failure. PMID- 6913951 TI - Why do we have to have curriculum change in nursing? PMID- 6913950 TI - Peritoneal dialysis: a rediscovery. PMID- 6913952 TI - Health visiting. PMID- 6913953 TI - Health visiting: health promoting policies. PMID- 6913954 TI - Health visiting: the view depends on where you sit. PMID- 6913955 TI - Health visiting. And father came too. PMID- 6913956 TI - Health visiting: first encounters of a health visiting kind. PMID- 6913957 TI - Health visiting: 'Do I take the yellow one after breakfast?'. PMID- 6913958 TI - Power (back) to the people. PMID- 6913959 TI - Death wish. PMID- 6913960 TI - Research/staff nurse: a double life. Interview by Tamara Ross. PMID- 6913962 TI - The 0-5 year old mentally handicapped child. 1. From the nursing viewpoint. PMID- 6913963 TI - Urinary incontinence: ways to help solve a sensitive problem. PMID- 6913961 TI - Epidemiology. 3. Screen test. PMID- 6913964 TI - Nursing care study - motor neuron disease: 'Must not despair.'. PMID- 6913966 TI - State final 'blues'. PMID- 6913965 TI - Tip of an iceberg? PMID- 6913969 TI - NM pay campaign: be prepared! PMID- 6913968 TI - NM pay campaign: taking poll position. PMID- 6913967 TI - NM pay campaign: questions in parliament. PMID- 6913970 TI - Burns: playing with fire? PMID- 6913972 TI - Child development. 2. Bottom shuffle, bumps and babbles. PMID- 6913971 TI - Very low birthweight infants. 2. From little acorns. PMID- 6913974 TI - The 0-5 year old mentally handicapped child. 3. No time is a good time. PMID- 6913973 TI - Occupational health nursing: all in a day's work. PMID- 6913975 TI - Epidemiology. 5. Accidents will happen. PMID- 6913977 TI - A return to the bedside. PMID- 6913976 TI - Picture quiz: children at risk. PMID- 6913978 TI - [Combined rehabilitation of lung patients]. PMID- 6913979 TI - [Difficult patient, or is it difficult for the patient...]. PMID- 6913981 TI - [In a D and D1 infant care unit]. PMID- 6913980 TI - [Early rehabilitation in hemiplegia and hemiparesis]. PMID- 6913983 TI - [Correspondence nursing studies]. PMID- 6913982 TI - [Current diagnostic trends in intestinal diseases]. PMID- 6913984 TI - [Planning patient nursing care]. PMID- 6913985 TI - [Oral hygiene]. PMID- 6913986 TI - [Patient before the operation]. PMID- 6913987 TI - [Gold Cap]. PMID- 6913989 TI - [Place and role of the master of nursing degree]. PMID- 6913988 TI - [Tournament and self-education]. PMID- 6913990 TI - [Concept of the process of nursing care]. PMID- 6913991 TI - [Adaptation in the ward]. PMID- 6913992 TI - [Natural family planning]. PMID- 6913993 TI - [School difficulties]. PMID- 6913994 TI - [Rehabilitation of children with congenital defects of the motor apparatus]. PMID- 6913995 TI - [Health education and educational needs]. PMID- 6913996 TI - [Prolactin in pregnancy, labor and the puerperium]. PMID- 6913998 TI - [Computerized tomography]. PMID- 6913997 TI - [Nursing process: realization of the care plan]. PMID- 6913999 TI - [Child and adolescent nutrition]. PMID- 6914000 TI - [Staszow's "white Sundays" and ordinary days]. PMID- 6914001 TI - [Dental caries]. PMID- 6914002 TI - [Further comment on Lassa fever]. PMID- 6914003 TI - [Not just our affair]. PMID- 6914004 TI - [Structure of supervision]. PMID- 6914005 TI - Obstetrics: when the doctor doesn't arrive. PMID- 6914006 TI - R.N. employment physicals: disclosing results. Case in point: Dornak v. Lafayette General Hospital (399 So 2d 168-LA). PMID- 6914007 TI - Legal case briefs for nurses: LA: suicide: nursing service adequate. GA: O.R. hijinks: no liability. PMID- 6914008 TI - R.N. staffing agencies: hospital relations. Case in point: homemakers v. Gonzales; MPP Duval v. Gonzales (400 So. 2d 965-FL). PMID- 6914009 TI - Empathic perceptions of nursing students: self-reported and actual ability. AB - Clearly, one of the goals of nursing education is to enhance the empathic functioning of nursing students. In this study we examined one major component of empathic functioning--accuracy of empathic perceptions--in both undergraduate (n = 66) and graduate nursing students (n = 50) We predicted that actual ability (Kagan's Affective Sensitivity Scale) and self-perceived ability would vary as a positive function of educational level. The results supported the first prediction, even when the effects of the subjects' age and amount of prior nursing experience were controlled. Self-perceived ability, however, was not reliably related to educational level, although it did relate to actual ability. Compared with students in other "helping" professions, the students in this study appeared relatively empathic. Finally, students' perceptions of their difficulty in detecting and handling other particular feeling states suggest that nursing needs to take a more "affect-specific" approach to empathic functioning. PMID- 6914010 TI - Correlates of depression in chronic dialysis patients: morbidity and mortality. AB - A group of 74 end-stage renal disease outpatients on dialysis completed on of seven forms of the Depression Adjective Check List (DACL) (Lubin, 1981) once a month over a 12-month period. Patient cooperation in filling out the DACL was 95%, indicating patient's acceptance of this fairly unobtrusive instrument. The distribution of usable DACL scores of 53 patients was trifurcated: high = one SD above the mean; medium +/- one SD from the mean; and low = more than one SD below the mean. A one-way ANOVA on the mean number hospitalizations during the 12-month period for each group was significant, F (2,50) = 8.11, p less than .01. The mean number of hospital admissions was highest for the high depression group and lowest for the low depression group. DACL scores of seven patients who died were significantly higher than for the 46 survivors, t (60) = 4.44, p less than .01. PMID- 6914011 TI - A strategy for surveying nursing practice in institutional settings. AB - Two major obstacles encountered when surveying nursing practice in institutional settings are obtaining a representative sample and collecting an adequate number of observations at a reasonable cost. Past efforts to deal with these problems are reviewed briefly, and results are reported from a two-stage mail survey of a national sample of critical-care nurses. The first stage involved attempts to procure a list of staff nurses from head nurses of critical-care units at 240 randomly selected institutions. An 86% response rate was obtained. The second stage involved mailing questionnaires to a random sample of 600 critical-care nurses listed. Completed, mailed questionnaires were obtained from 87%. Little evidence of bias due to administrative selection and/or volunteerism was found in the lists of staff nurses. An analysis of membership in professional nursing organizations indicates that more than one half of the nurses who responded to this survey would not have been included had the sample been selected from organizational membership lists. PMID- 6914012 TI - Beckstrand's concept of practice theory: a critique. PMID- 6914013 TI - Issues and approaches to estimating interrater reliability in nursing research. AB - Following a general discussion of the meaning of and need for reliability estimates, four different approaches to the estimation of interrater reliability are discussed: correlational techniques, comparison of means, percentage of agreement, and generalizability theory techniques. Data from a nursing research project are used to illustrate the method and to interpret reliability estimates obtained by each approach. The estimates vary widely, from a low of .03 (using a percentage of agreement technique), to a high of .68 (using a correlational approach). The usefulness and advantages of generalizability theory techniques, which afford the most comprehensive and complex means of assessing reliability, are emphasized. PMID- 6914017 TI - Safe care standards for seniors. PMID- 6914014 TI - Nurse recruitment advertising: a study. PMID- 6914015 TI - What is NSNA? PMID- 6914016 TI - How to select an ad agency. PMID- 6914018 TI - If you want a voice -- now's the time to speak up. PMID- 6914019 TI - The year of the elderly. PMID- 6914020 TI - [Cancer of the right colon: symptoms and therapy]. PMID- 6914023 TI - [Mister M.'s hemorrhagic rectocolitis]. PMID- 6914021 TI - [Hemorrhagic rectocolitis]. PMID- 6914022 TI - [Lesions to be treated without delay]. PMID- 6914025 TI - [Acute appendicitis and its complications]. PMID- 6914024 TI - [Salazopyrine]. PMID- 6914028 TI - [Cancer of the left colon: symptoms and therapy]. PMID- 6914026 TI - [Epidemiology and prevention of cancer of the colon]. PMID- 6914027 TI - [Occlusive syndromes]. PMID- 6914029 TI - [Evaluation of hospital nursing care. A qualitative evaluation method]. PMID- 6914030 TI - [County Council Society's president: goal is a coordination of educational policy and labor market policy]. PMID- 6914031 TI - [Prognosis of the need for nurses, nursing assistants and nursing home assistants up to 1992: social administration expects a tenfold increase in nursing home assistants]. PMID- 6914032 TI - [Fenja's birth is our birth]. PMID- 6914033 TI - [Then my little sister was born]. PMID- 6914034 TI - [What are the general and what are the specific needs?]. PMID- 6914035 TI - [Health visitor supervision in 1979: visits to many children instead of many visits to special children at risk]. PMID- 6914036 TI - [Minister of the Interior at the County Council Society's general meeting: education of nursing personnel proceeds slowly]. PMID- 6914037 TI - [Executive Board meeting 8-9 September 1981: current emphasis on need for additional educational capacity]. PMID- 6914038 TI - [Psychiatric nurse's role and function in clinical activities: awareness of and ability for ways to professional identity]. PMID- 6914039 TI - [Theoretical problems remain an important tool in oncological nursing]. PMID- 6914040 TI - [Drug information: antiparkinson agents III. Amantadine (Symmetrel), bromocriptine (Parlodel)]. PMID- 6914041 TI - [Scandinavian Journal for Nursing Research is an exciting enterprise]. PMID- 6914042 TI - [If we neglect the spiritual needs we cannot speak of total care]. PMID- 6914043 TI - [Proposal to economize on health visitor's visits in pregnancy]. PMID- 6914045 TI - [Open letter from the KKS (Copenhagen's Community Nurses' Association) to Copenhagen's politicians: weary and disheartened nurses like nothing better than to retire]. PMID- 6914046 TI - [Nurse's most important working tool - herself]. PMID- 6914044 TI - [Positive results of nurses' initiative: structure change provides increased efficiency without changing standards. Interview by Inger Rosenkvist]. PMID- 6914047 TI - [New classification of drugs: ATC-code introduced]. PMID- 6914048 TI - [Self care: increased co-influence reinforces interest for own and others' health]. PMID- 6914049 TI - [Why are we forced to also be members of the A-fund?]. PMID- 6914050 TI - [Nursing's Magna Carta gets meaning]. PMID- 6914051 TI - [Who manipulates in discussions about prison isolation?]. PMID- 6914052 TI - [Drug information: malaria agents]. PMID- 6914053 TI - [Amnesty International Danish nurses' group on isolation imprisonment: it is very difficult to consider isolation a link in rehabilitation]. PMID- 6914055 TI - [Myths and realities in the shortage of nurses]. PMID- 6914054 TI - [How do head nurses spend their time?]. PMID- 6914056 TI - [As a patient you experience things from the inside out]. PMID- 6914057 TI - [Child held securely without the straps acting like a straightjacket]. PMID- 6914058 TI - [The concept of self care defined and applied in a nursing model]. PMID- 6914059 TI - [Patient and human being]. PMID- 6914060 TI - An inhibitor from corn blocks the hypotensive action of plasma protein fraction and active Hageman factor. PMID- 6914061 TI - [The advisory Committee for education in the field of nursing - an account from Brussels (II)]. PMID- 6914063 TI - [Patient care (I) - report of a literature study]. PMID- 6914062 TI - [Double binds, paradoxes--contradictions]. PMID- 6914065 TI - [Trace elements]. PMID- 6914064 TI - [Systematic care in an artificial kidney department]. PMID- 6914068 TI - [Art in Hospital Westeinde]. PMID- 6914067 TI - [Patient care (II) - report of a number of interviews]. PMID- 6914066 TI - [Sexuality and mental retardation - a real connection]. PMID- 6914069 TI - [Concern for care after hospital - team work hospital-district nursing]. PMID- 6914070 TI - [Design and procedures of a contact-group hospital-after care]. PMID- 6914071 TI - [Patient care (III) - report of an observation study]. PMID- 6914072 TI - [Contracting with patients]. PMID- 6914074 TI - Why did you become an OR nurse? PMID- 6914073 TI - [Euthanasia and the problem of suicide in mental disorders]. PMID- 6914075 TI - Helpful hints for better lectures. PMID- 6914076 TI - [Pancreatic enzymes preparations]. PMID- 6914077 TI - A technique for performing an ovariectomy on a hamster. PMID- 6914081 TI - Treatment of colic in horses based on empirical evidence. PMID- 6914080 TI - Otitis media associated with Staphylococcus epidermidis and Psoroptes cuniculi in a rabbit. PMID- 6914079 TI - Histomoniasis in zoo birds. PMID- 6914078 TI - Secobarbital/dibucaine combination as a euthanasia agent for dogs and cats. PMID- 6914082 TI - Equine contraction. PMID- 6914083 TI - Atresia ani and atresia of the external genitalia in a pig. PMID- 6914084 TI - Outbreak of respiratory disease in a feedlot in eastern Kansas. PMID- 6914085 TI - Spastic paresis in beef and dairy cattle. PMID- 6914089 TI - Grass eating by carnivores. PMID- 6914088 TI - Hepatic function--3: protein metabolism and blood ammonia tests. PMID- 6914086 TI - The use of Vetrap bandaging tape to manage bovine foot problems. PMID- 6914087 TI - Feeling okay about your fees? PMID- 6914090 TI - A reference file for small animal practices. PMID- 6914091 TI - Persistent penile frenulum in a cocker spaniel. PMID- 6914094 TI - The use of knowledge and health policy planning: forms and functions of the relationships. PMID- 6914093 TI - Proceedings of the 1981 conference of the Western Society for Research in Nursing. PMID- 6914092 TI - The rare Shar Pei dog: medical and surgical problems. PMID- 6914096 TI - Clinical competencies for critical care nurses. PMID- 6914095 TI - Self-regulatory mental processes and patient recovery. PMID- 6914098 TI - Ethical issues in nursing research. PMID- 6914097 TI - Social behavior and psychosocial adjustment of single- and two-parent children. PMID- 6914099 TI - Strategies for teaching nursing research. Desentization of the research phobia: instructor as therapist. PMID- 6914100 TI - Researchmanship: the politics of research revisited. PMID- 6914101 TI - Health policy and research: revisited. PMID- 6914103 TI - [Therapeutic application of kallikrein in idiopathic oligo- and asthenozoospermia (author's transl)]. AB - The addition of kallikrein to frozen semen after thawing increases the sperm motility in cases of moderate asthenozoospermia. In native semen maximal increase of motility is found two hours after the addition of kallikrein. In vivo an increase of sperm motility was noted in cases of oligozoospermia and asthenozoospermia during treatment with 600 KE kallikrein/day. The wives of 9 patients with asthenozoospermia became pregnant during kallikrein therapy. PMID- 6914102 TI - A study of fitness and cardiovascular risk factors in male office workers. PMID- 6914104 TI - Health at work. PMID- 6914105 TI - Health screening--its application to occupational health. PMID- 6914106 TI - Alcohol education in industry--prevention and intervention: an Irish response. PMID- 6914107 TI - The recluctant bedfellows: medicine and the law. PMID- 6914108 TI - Patient classification systems: report of A.A.R.N. Ad Hoc Committee. PMID- 6914109 TI - Nursing ... as I see it. PMID- 6914111 TI - The law and the lamp: cornerstones of consent. PMID- 6914110 TI - Why don't they stop having so many babies? PMID- 6914112 TI - The automated systems approach to nursing. PMID- 6914113 TI - Hopkins dedicating +3.5 million emergency room to treat half of region's trauma cases. PMID- 6914114 TI - Pluralism and competition: a possibility for primary care. PMID- 6914115 TI - Decreasing respiratory compromise during infant suctioning. PMID- 6914116 TI - Making change to flex time. PMID- 6914117 TI - Infection control: putting principles into practice. PMID- 6914118 TI - Infection control: how to collect specimens and evaluate results. PMID- 6914119 TI - Infection control: Guidelines for prevention of hospital acquired infections. PMID- 6914120 TI - Infection control: Serratia--an endemic hospital resident. PMID- 6914121 TI - Dealing with feelings: handling anger: responding vs. reacting. PMID- 6914122 TI - Drug data: short-and long-acting benzodiazepines. PMID- 6914123 TI - The legal side: an occupational nurse's liability. PMID- 6914124 TI - Profile: RN launches cruise service for dialysis patients. PMID- 6914125 TI - Occluding junctions surrounding cystoid spaces in the human peripheral retina. A thin-section and freeze-fracture study. AB - Transmission electron microscopic examination of thin sections and freeze fracture replicas of areas neighboring cystoid spaces in the peripheral human retina reveals extensive networks of occluding junctions on all sides of these spaces. These junctions may be responsible for the fact that, in spite of the absence of an epithelial lining, fluid from the spaces of cystoid degeneration and retinoschisis does not leak into the surrounding retina, which would lead to their collapse. PMID- 6914126 TI - Ocular hypotensive action of labetalol in rabbit and human eyes. AB - The ocular hypotensive action of labetalol, a drug endowed with alpha- and beta adrenergic receptor-blocking properties, was studied in both rabbit and human eyes. In the rabbit, using two different models of experimentally induced ocular hypertension, an impressive decrease of IOP was seen after topical administration of the drug. In this species labetalol was found to be at least as effective as timolol and more active than pilocarpine or propranolol. In human eyes suffering from glaucoma, however, its effectiveness was much less evident and clearly inferior to that of timolol. PMID- 6914127 TI - Regeneration of damaged ciliary epithelium in aphakic and pseudophakic eyes. AB - Mechanically damaged ciliary epithelium in aphakic and pseudophakic rabbit eyes was studied for up to 2 years after extracapsular lens extraction. Histopathological examination of the epithelium revealed more severe damage in pseudophakic eyes. The nonpigmented epithelium (NE) was missing from the middle to basal portion of each ciliary process. Regenerative ability of the NE was extremely poor. The damaged NE continued to disappear for at least 2 years, and only the pigmented epithelium (PE) covered the stroma. In some of the affected areas, the stroma of the ciliary body (CB) was substituted by fibrous materials. PMID- 6914128 TI - [The origin of the choroidal excavation in b-scan-sonography--an experimental and clinical study (author's transl)]. AB - In many uveal lesions a choroidal excavation can be demonstrated by B-scan sonography. By clinical and experimental methods it can be shown that this phenomenon is elicited by differences of reflectivity between the highly reflective choroid and low reflecting uveal lesions. Therefore, the choroidal excavation is not specific for one tumor, but will always be demonstrable, when a low reflective lesion (melanoma, hemorrhage) is present in the choroid. High reflective lesions (metastases, hemangioma) do not exhibit such an excavation. PMID- 6914129 TI - [Principal possibilities and limitations of fluorescent angiographic procedures for the measurement of the flow-physical magnitudes of the retinal circulatory system (author's transl)]. AB - Flow-physical magnitudes are presented that describe the retinal circulatory system. The principal possibilities and limitations of fluorescent angiographic procedures for the measurement of these magnitudes are discussed. On this basis, we compare fluorescentophthalmoscopic measurements of time, serial angiography, and cinematography with densitometric evaluation of the negatives, integral fluorophotometry, 'two point' photometry, and the application of television with evaluation of the video signal. PMID- 6914131 TI - Ocular kinetics of 8-methoxypsoralen. An experimental study with pigmented and albino rabbits without UVA-stimulation. AB - Tritiated 8-methoxypsoralen (8-MOP), with radioactivity in the ring system, was injected into both pigmented rabbits and albino rabbits; at 0.5, 1, 2, 4, 6, and 24 h after 8-MOP injection the animals' plasma and ocular radioactivities were determined by liquid scintillation counting. The experiment was done without photostimulation but in incomplete darkness. The plasma radioactivity declined rapidly during the first hour, peak radioactivity occurring in the first samples of vascularized ocular structures taken 0.5 h after the injection. The radioactivity of these tissues generally declined rapidly and similarly in both animal groups. The 1, 2, and 4 h samples of pigmented animals formed an exception; in these the radioactivities in the iris-ciliary body and the retina choroid of the pigmented animals showed increased activities that were statistically significant, and the plasma radioactivity was exceeded by two to three times. The radioactivities in the internal parts of the eye were lower than in the vascular parts. The radioactivity in the lens reached a peak in the specimens taken 1-2 h after injection and remained at the level of the plasma radioactivity for the rest of the 24 h. PMID- 6914132 TI - Ultrastructural changes in hamster lung four hours to twenty-four days after exposure to elastase. AB - A single endotracheal instillation of elastase initiates a series of changes in animal lungs that results in a condition resembling human panlobular emphysema. An ultrastructural examination of this series of changes was conducted on the lungs of male golden hamsters exposed to 3H-methylated pancreatic elastase and sacrificed at intervals between 4 hour and 24 days after exposure to enzyme. Lung tissue between 4 and 48 hours showed evidence of hemorrhage and progressive degradation of elastic fibers. Very little indication of epithelial cell damage accompanied these changes. Four days after exposure to elastase, synthesis of new elastic fibers began with the appearance of small clumps of microfibrils in close association with interstitial cells, fibroblasts, and smooth muscle cells. There was also evidence of alterations in alveolar type II cells at this time. Small fibrillar elastic fibers continued to be present in the lung through twenty-four days and may represent a slow repair process or may indicate a structural difference in elastic fibers synthesized after exposure to elastase. Evidence of the continued degradation of elastic fiber could be found up to 16 days after exposure to elastase, revealing that repair processes were occurring in some areas of the lung while destructive process still predominated in other areas. PMID- 6914133 TI - To cut costs, let RNs compete. PMID- 6914130 TI - Immune response evoked by antigen injection in the rabbit vitreous combined with immunopotentiation. AB - Intravitreal injection of rabbits with antigen evokes a cell-mediated and a humoral immune response as detected by lymphocyte stimulation, skin testing, and hemagglutination tests. The results of the lymphocyte stimulation test largely correlate with the clinical evaluation of the inflammation process. Rabbits which have been sensitized by Freund's complete adjuvant at the moment of intravitreal antigen injection demonstrate a biphasic cell-mediated immune activity to this antigen. Intradermal or intraocular antigenic challenges of the rabbits 5 weeks following the intravitreal injection evoke responses with the characteristics of an Arthus reaction. At that moment, antigen-sensitized lymphocytes are found in the draining preauricular lymph nodes but not in the contralateral lymph nodes, suggesting separate functioning of these lymph tissues. PMID- 6914134 TI - ANA monitors development of U.S. hospice movement. PMID- 6914135 TI - Three speak up for nurses as hospice directors. PMID- 6914136 TI - 'Small, sharp' staff meets county hospice needs. PMID- 6914137 TI - Danish leader urges nurses to unite for influence. PMID- 6914139 TI - National panel recommends decision making by RNs. PMID- 6914138 TI - A report from ANA's Executive Director. PMID- 6914140 TI - As I see it--bounties reward extra work. PMID- 6914141 TI - Pay rates for women are discriminatory. PMID- 6914142 TI - Practice acts in 6 states come under sunset review. PMID- 6914144 TI - Sheila Burke urges students to be activists. PMID- 6914145 TI - Notable nurses, friends offer advice to graduates. PMID- 6914143 TI - Patton cells on staff nurses to lead. PMID- 6914146 TI - Students choose nursing as route to varied goals. PMID- 6914149 TI - Preparing for patients with multisystem trauma. PMID- 6914148 TI - Tests give answers about effectiveness of inservice programs. PMID- 6914147 TI - Effects of oligopeptide chloromethylketone administered after elastase: renal toxicity and lack of prevention of experimental emphysema. AB - The effectiveness of N-acetyl-L-alanyl-L-alanyl-L-prolyl-L-alanine chloromethylketone (AAPACK) in preventing the development of experimental emphysema in hamsters, when administered 60 min after exposure to elastase, was studied. When 19 mg of AAPACK was injected intraperitoneally in divided doses commencing 60 min after the intratracheal instillation of pancreatic elastase, the development of emphysema was not prevented using morphologic, morphometric, and physiologic means of evaluation. Thirty-eight per cent of hamsters given AAPACK became ill and lost weight. At autopsy, these hamsters had a renal tubular nephropathy and focal interstitial disease. The glomeruli were spared. Five of these hamsters with renal tubular lesions had azotemia. Focal necrosis was observed in the heart of 3 and in the liver of 5 animals with renal lesions. These studies indicated that AAPACK, in the protocol followed where elastase precedes administration of the inhibitor, (1) does not prevent the development of elastase-induced emphysema, and (2) does produce a unique renal tubular nephropathy. PMID- 6914150 TI - A case for trauma room 10. PMID- 6914152 TI - Special needs of teenage cesarean patients. PMID- 6914151 TI - Preoperative teaching for cesarean birth. PMID- 6914153 TI - Making work in the OR more satisfying. PMID- 6914154 TI - Hepatic artery cannulation. PMID- 6914155 TI - Importance of secondary enzyme-substrate interactions in human cathepsin G and chymotrypsin II catalysis. PMID- 6914156 TI - Kallikrein concentrations in the plasma, lymph, thoracic, and cerebrospinal fluid of rabbits. AB - Since there is not an established method for selective assay of kallikrein, it is still unsettled whether kallikrein is absorbed from the intestine or not. Kallikrein was injected into the duodenum of rabbits which had been fasted for 24 hr and the concentrations of the drug in the plasma, lymph and cerebrospinal fluid were determined by an enzymatic method using substrate TAME or Peptide-MCA (hereafter, briefly as TAME method or Peptide-MCA method). An unknown substance, which splits the substrate TAME, appeared in the plasma, lymph and cerebrospinal fluid after injection of kallikrein into the rabbit duodenum. In rabbits which underwent pancreatectomy, kallikrein was not absorbed from the intestine and the unknown substance was not detected in any of the plasma, lymph and cerebrospinal fluid. PMID- 6914157 TI - Prekallikrein (Fletcher factor) deficiency in typhoid fever. PMID- 6914158 TI - [Secondary prevention of gastric cancer in a risk group of persons without gastric acid. 2nd communication (author's transl)]. AB - More than 6,000 predominant unselected persons were examined by tubeless gastric acid test using the "Desmoidpille" and by simultaneous determination of uropepsin according to West et al. About 1,000 probands demonstrating a lacking acid secretion were recognized as risk group and taken into supervision over several years since 1972. In this risk group 20 cases of gastric cancer were detected, 9 of them already by first investigation. 5 gastric cancers were found during the follow-up as true early gastric cancers. In 5,200 probands without risk signs (normal acid test) only 6 cases of gastric cancer were observed during time of follow-up. So it is a high risk group indeed, we have selected. Regarding the casuistry of 7 persons, younger than 70 years of age, with gastric cancer detected during follow-up, 4 of them survived, such a dispensaire included in a general geriatric care seems useful to practice. PMID- 6914159 TI - Nursing diagnosis: professional displacement, as I see it. PMID- 6914160 TI - Guidelines for the safe handling of cytotoxic drugs. PMID- 6914161 TI - College of Nursing, Australia - a glimpse at the past - a view of the present - a vision of the future. PMID- 6914162 TI - The nurse and the law: drama in the theatre. PMID- 6914163 TI - Drug interactions with cimetidine. PMID- 6914166 TI - Communication and nursing. PMID- 6914167 TI - The disabled family--a personal perspective. PMID- 6914168 TI - The role of Armidale C.A.E. in the Pacific region. PMID- 6914164 TI - A normal labour - with a summary of ante natal and post natal care. PMID- 6914169 TI - Family centered care: a transatlantic study. PMID- 6914165 TI - Child maltreatment : an Infant Welfare perspective. PMID- 6914170 TI - A philosophy of clinical education. PMID- 6914171 TI - The future: roadblocks and remedies. PMID- 6914172 TI - Hepatitis B and pregnancy. PMID- 6914173 TI - Reactions to stoma surgery. PMID- 6914174 TI - "Mumps" the word but you have yet another vaccine deficiency. PMID- 6914175 TI - German nurses striving for formation of a central body. PMID- 6914176 TI - Nutritional teamwork strategies. PMID- 6914177 TI - Thought process of delusions. PMID- 6914179 TI - Charting tomorrow today. PMID- 6914178 TI - Child abuse. PMID- 6914180 TI - The nurse as an agent for social change: personal reflections on some recollections. PMID- 6914181 TI - The proposal in nursing and allied health research:foundation for success. PMID- 6914182 TI - Special assessment units. PMID- 6914183 TI - On the safety of homebirth. PMID- 6914184 TI - The psychology of a neurasthenic. PMID- 6914185 TI - Opening address: the nurse as an agent for social change. PMID- 6914186 TI - Infection. PMID- 6914187 TI - Packaging for sterilisation. PMID- 6914189 TI - How to encourage integration. PMID- 6914188 TI - Women, the law, and provocation. PMID- 6914190 TI - The grading dilemma in nursing education. PMID- 6914191 TI - Home births and flying squads. PMID- 6914192 TI - Coping. PMID- 6914193 TI - Playgroup and how to encourage integration. PMID- 6914194 TI - Cholesteryl esters are bound by a peptide-initiation and a peptide-elongation factor. AB - Significantly higher quantities of cholesteryl 14-methylhexadecanoate than of cholesteryl laurate and cholesteryl palmitate are bound by a homogeneous peptide initiation factor and purified peptide-elongation factor 1. Cholesteryl 14 methylhexadecanoate may function as a specific allosteric modifier changing the conformation of protein synthesis factors and thus modulating the activity of their binding sites. PMID- 6914196 TI - The molecular-weight dependence of the rate-enhancing effect of heparin on the inhibition of thrombin, factor Xa, factor IXa, factor XIa, factor XIIa and kallikrein by antithrombin. AB - Heparin fractions of different molecular weight and with high affinity for antithrombin were studied with respect to their ability to potentiate the inhibition of activated clotting factors by antithrombin. Inhibition of thrombin, Factor IXa and Factor XIa showed similarities in the dependence on the molecular weight of heparin and was found to decrease with decreasing molecular weight. Inactivation of Factor Xa, Factor XIIa and kallikrein was, however, less dependent on the size of the polysaccharide and, to a great extent, was potentiated even by low-molecular-weight heparin fractions that had virtually no effect on the inhibition of thrombin, Factor IXa and Factor XIa. PMID- 6914195 TI - Human plasma kallikrein. A rapid purification method with high yield. AB - A simple method for isolation of kallikrein from human plasma is described. Before activation of the enzyme with acetone, the plasma was treated with 0.2 M methylamine at pH 8.2 to inactivate alpha 2-macroglobulin and thus prevent the irreversible binding of the active enzyme to the inhibitor. The enzyme was adsorbed on soya-bean trypsin inhibitor-Sepharose 4B and eluted with 5 mM-NaOH, pH 11.3. It was further purified by immunoadsorption of contaminating proteins, and gel chromatography on Ultrogel AcA 44. About 3 mg of kallikrein was obtained from 400 ml of plasma (35% yield). The purified enzyme was shown to be homogeneous by electrophoretic and immunological criteria. The specific activities against benzyloxycarbonylphenylalanylarginine methylcoumarylamide, prolylphenylalanylarginine methylcoumarylamide and tosylarginine methyl ester were higher than any previously reported. The purified enzyme was resolved into two forms of mol.wts. 88 000 and 86 000 in sodium dodecyl sulphate/polyacrylamide gel electrophoresis without reduction. Each consisted of three chains linked by disulphide bonds, one containing the reactive serine residue (mol.wt. 36 000 or 34 000), and two additional chains (mol.wt. 28 000 and 22 000). PMID- 6914197 TI - Equilibration of leucine between the plasma compartment and leucyl-tRNA in the heart, and turnover of cardiac myosin heavy chain. AB - By 30min continuous infusion of [3H]leucine into rats, the specific radioactivities of plasma leucine and tissue-free and tRNA-bound leucine in heart were equal. The specific radioactivity of leucyl-tRNA in heart therefore follows a time course identical with that of plasma leucine soon after the start of infusion. The half-life of cardiac myosin heavy chain (5.5 days) was the same as that reported by other investigators who used the pulse-labelling protocol. PMID- 6914199 TI - Primary health care. PMID- 6914200 TI - The role of the vocational counselor. PMID- 6914198 TI - Early effects of dimethylnitrosamine on the initiation of protein synthesis in mouse liver. AB - 1. Dimethylnitrosamine (37.5 mg/kg body wt.) was administered to mice by a single intraperitoneal injection, and the early effects on protein synthesis and related functions were studied in a liver S-30 system. 2. The incorporation of [14C]leucine into protein decreased rapidly after dimethylnitrosamine administration. The effect was associated with a decreased ability of the system to utilize methionyl-tRNAfMet and formyl-methionyl-tRNAfMet for 80 S ribosomal initiation-complex formation (primary initiation), and a loss of poly(A) containing RNA from the postmicrosomal fraction. All the three effects developed simultaneously, and were clearly demonstrable within 15 min. 3. Initiation complex formation in the polyribosomal fraction (re-initiation) was decreased to the same extent as the primary initiation, indicating that the initiation defect was not a result of the decrease in free mRNA. 4. The inhibition of initiation was only manifest at the joining of the 40 S pre-initiation complex to 60 S ribosomal subunits. It was not a result of methionyl-tRNAfMet deacylation. The functions between the formation of the methionyl-tRNAfMet-containing 80 S ribosomal complex and the first translocation on the ribosome were not involved, since the incorporation of formylmethionine into N-terminal polypeptides decreased to the same extent as the 80 S initiation-complex formation. 5. Inhibitors of protein synthesis (cycloheximide and pactamycin) decreased poly(A) containing RNA in the postmicrosomal fraction in a similar way to dimethylnitrosamine. PMID- 6914201 TI - Demography. PMID- 6914202 TI - The protein synthetic activity in vitro of ribosomes differing in the extent of phosphorylation of their ribosomal proteins. AB - We describe a re-examination of the cell-free protein synthetic activity of eukaryotic ribosomes having proteins phosphorylated to different extents. Ribosomal 40 S subunits were isolated both from a variety of cells in which there is relatively little phosphorylation of ribosomal protein S6, and from cells subjected in vivo to different stimuli that promote the extensive phosphorylation of protein S6. The ability of these subunits to bind Met-tRNA as well as the second amino acyl-tRNA (Val-tRNA) was compared in the presence of highly purified initiation factors, elongation factor EF-1 at various concentrations of 60S subunits, 9 S globin mRNA and potassium ions. The ability of the subunits to synthesize polyphenylalanine was also studied using highly purified elongation factors. In no case was any significant difference in activity observed between ribosomes with protein S6 phosphorylated to different extents. Similar, though less extensive, studies were preformed comparing 60 S ribosomal subunits differing in the extent of phosphorylation of the acidic phosphoprotein, L gamma , and of L14. No difference in activity was observed between these ribosomes. PMID- 6914203 TI - Relative risk of adolescent drug abuse: Part II. Intrapsychic variables. AB - The total sample size for the study of intrapsychic variables was 252 (152 non drug users and 100 life-time users including 69 current users). Using a multiphasic personality questionnaire, the Eysenck personality inventory and an orientation questionnaire, the authors found that high orientation, extraversion, anxiety and psychopathic deviate scores were associated with a relative risk of drug use. No significant difference is reported between the mean scores of users and non-users on mania, paranoia, depression, schizophrenia, hysteria and neuroticism. PMID- 6914204 TI - A note on the morphine content of lanced poppy capsules purchased as "dried flowers". PMID- 6914205 TI - The question of onymity and anonymity of a questionnaire in a drug use survey. AB - In a drug use survey of 457 final-year medical students a self-administered questionnaire included the controversial question whether such questionnaires should be onymous or anonymous. Definite answers either in favour of or against anonymity were given by 216 respondents. Of these, 72.2 per cent were in favour of anonymity, only 27.8 per cent favoured onymity. Among those who provided ambiguous answers, or who did not respond on the issue of anonymity vs. onymity, there were significantly more drug users. Where there was no family history of drug use, or where parents definitely disapproved of drug use, a high proportion of respondents were in favour of anonymity. PMID- 6914206 TI - Interrelationships of glandular trichomes and cannabinoid content. I: Developing pistillate bracts of Cannabis sativa L. (Cannabaceae). AB - Gland number and cannabinoid content for three clones of Cannabis were compared. Cannabinoid levels and mature glands were quantified throughout progressive stages of pistillate bract development in order to define possible interrelationships between glands and cannabinoids. Similar trends occurred among the clones for each gland type while individual cannabinoids displayed a different pattern in each clone. Gland initiation and development as well as cannabinoid synthesis were found to occur during bract ontogeny for all three clones. A positive correlation existed for the total number of capitate glands per bract compared to the total cannabinoid content of the bract. The study also suggested that the glands may contain the majority of the cannabinoids present in the bract. PMID- 6914207 TI - Barriers to re-entry: problems are many, solutions few. PMID- 6914208 TI - Why don't nurses do patient-centered nursing? PMID- 6914209 TI - Upgrading your oral hygiene protocol for the patient with cancer. PMID- 6914210 TI - Surgical care of the aged. PMID- 6914212 TI - Four steps to quality assurance. PMID- 6914211 TI - An alternative birth center proposal. PMID- 6914213 TI - Flow sheets: meeting the charting challenge. PMID- 6914214 TI - Frankly speaking: is there a case for the voluntary agency? PMID- 6914215 TI - Travellers' diarrhea. PMID- 6914216 TI - You and the law. PMID- 6914217 TI - Purification and some properties of hog renal kallikrein. PMID- 6914218 TI - Human renal kallirein: purification and some properties. PMID- 6914219 TI - Respiratory infections. PMID- 6914220 TI - Could a defect in host-immunity be the cause of respiratory infections? PMID- 6914221 TI - Mycoplasmal pneumonias in the community hospital. The "unusual" manifestations become common. PMID- 6914222 TI - Pulmonary infections, in Southeast Asian refugees. PMID- 6914223 TI - Peri-emphysematous lung infection. AB - The difficulty in classifying pulmonary infection within areas of bullous emphysema may have contributed to the lack of appreciation of this entity. This process is important to recognize because: (1) the clinical picture is usually benign:; (2) it may be confused with tuberculosis, fungal disease, and carcinoma of the lung; and (3) radiographic resolution may be slow. For these reasons, pneumonitis which occurs within emphysematous lung may have been previously considered as slowly resolving pneumonias. The development of air-fluid levels within bullae has been called "infected emphysematous bullae." We believe that this phrase is misleading since there are no bacteriologic data to support the presence of infection within the bullae containing fluid. In fact, direct sampling of intrabullous fluid has been rarely reported and, if obtained, has been generally negative for bacteria. Furthermore, the clinical course in our patients is alos not consistent with infection within a space. Once fiberoptic bronchoscopy has excluded an obstructing endobronchial lesion, the physician may patiently follow the anticipated gradual resolution. We suggest that the phrase, "periemphysematous lung infection" best describes these related clinical radiological conditions. PMID- 6914224 TI - Occupational lung diseases I. PMID- 6914225 TI - Nursing: a social policy statement. PMID- 6914226 TI - The meaning of self-care. PMID- 6914227 TI - Covert anxiety in the acute MI patient. PMID- 6914228 TI - Oral care and assessment in the critical care setting. PMID- 6914230 TI - Cardiac rehabilitation in the critical care unit. PMID- 6914231 TI - Interpretation of hemodynamic pressures and recognition of complications. PMID- 6914232 TI - Drug corner: bretylium tosylate (Bretylol). PMID- 6914229 TI - Dobutamine vs. dopamine. PMID- 6914234 TI - Arrhythmia quiz. PMID- 6914233 TI - Arrhythmia quiz: identify this arrhythmia. PMID- 6914235 TI - Cardiac output: physiologic variables and therapeutic interventions. PMID- 6914236 TI - The legalities of critical care. PMID- 6914239 TI - Procedural guidelines for the use of balloon-tipped, flow-directed catheters. PMID- 6914238 TI - Calcium and phosphate imbalances in renal failure. PMID- 6914237 TI - Ammonia inhalation--a case report. PMID- 6914240 TI - Drug corner: sodium bicarbonate. PMID- 6914241 TI - Propranolol hydrochloride: the critical care nursing implications. PMID- 6914242 TI - Drug corner: sodium nitroprusside (Nipride). PMID- 6914243 TI - Atrial electrograms--an asset to ECG monitoring. PMID- 6914244 TI - Are you listening? PMID- 6914245 TI - Arrhythmia quiz. PMID- 6914246 TI - The legalities of critical care. PMID- 6914247 TI - Nursing care plan: a patient with ARDS on mechanical ventilation. PMID- 6914250 TI - Arrhythmia quiz. PMID- 6914248 TI - Artificial mechanical ventilation of the adult. Part I: getting it started. PMID- 6914249 TI - Sleep deprivation and biological rhythms in the critical care unit. PMID- 6914252 TI - Drug corner: Lasix (furosemide). PMID- 6914251 TI - Are you listening? PMID- 6914254 TI - Toxic-shock syndrome. PMID- 6914253 TI - The legalities of critical care: informed consent. PMID- 6914255 TI - Disseminated intravascular coagulation. PMID- 6914256 TI - Nursing care plan: a patient with a thermal injury. PMID- 6914257 TI - Dobutamine vs. dopamine. PMID- 6914258 TI - Procedural guidelines for the use of balloon-tipped, flow-directed catheters. PMID- 6914259 TI - Arterial catheters: nursing management to decrease complication. PMID- 6914260 TI - Hepatorenal syndrome. PMID- 6914261 TI - The legalities of critical care: no code orders. PMID- 6914262 TI - A humanistic approach to counseling in critical care. PMID- 6914264 TI - Nursing care plan. PMID- 6914265 TI - Are you listening? PMID- 6914263 TI - Arrhythmia quiz. PMID- 6914266 TI - Mystery ECG. PMID- 6914268 TI - Your mystery arrhythmia strips. PMID- 6914267 TI - Drug corner: digitalis. PMID- 6914270 TI - Your mystery arrhythmia strips. PMID- 6914269 TI - Artificial mechanical ventilation of the adult. Part II: fine tuning. PMID- 6914271 TI - Individualizing diazoxide (hyperstat IV) dosage in the treatment of severe hypertension. PMID- 6914272 TI - Arrhythmia quiz. PMID- 6914273 TI - Are you listening? Clinical assessment skills. PMID- 6914277 TI - A teaching guide for patients with chronic lung disease. PMID- 6914274 TI - Echocardiography: an access route to the heart. PMID- 6914275 TI - Nursing intervention with the family of the critically ill patient. PMID- 6914279 TI - Sources of mixed venous blood samples. PMID- 6914276 TI - Home study program: acute respiratory failure in the patient with chronic obstructive lung disease. PMID- 6914278 TI - EKG of the month. PMID- 6914280 TI - Professional sharing: critical care patients have families. PMID- 6914282 TI - [Twin transfusion syndrome, a report of six twin pregnancies (author's transl)]. PMID- 6914283 TI - Sexual dysfunction: erectile dysfunction in the man with diabetes. PMID- 6914281 TI - The legalities of critical care: Supervisory liabilities. PMID- 6914284 TI - Sexual dysfunction: taking a sexual history. PMID- 6914285 TI - Sexual dysfunction: interview with a couple who have experienced sexual dysfunction secondary to diabetes mellitus. PMID- 6914286 TI - The pharmacist as a resource. PMID- 6914287 TI - A model for comprehensive diabetes dietary care. PMID- 6914288 TI - The use of support groups in diabetes education. PMID- 6914289 TI - Patient profile: control in an adolescent. PMID- 6914290 TI - Measuring the effect of patient teaching. PMID- 6914291 TI - The changing climate for credentialing in nursing. PMID- 6914293 TI - Will we survive? PMID- 6914292 TI - Nursing in a changing society. PMID- 6914294 TI - How becoming an independent nurse practitioner facilitated my spiritual development. PMID- 6914295 TI - How is healing accomplished? PMID- 6914296 TI - The American Holistic Nurses Association. PMID- 6914297 TI - Senior citizens' holistic health center. PMID- 6914300 TI - The ERA - into the breach. PMID- 6914298 TI - Becoming an independent nurse practitioner. PMID- 6914301 TI - New R.N. examination in '83. PMID- 6914305 TI - Time of transition: NSNA's view on educational preparation. PMID- 6914302 TI - Vision and hearing screenings - student nurses can help. PMID- 6914303 TI - Nursing service expectations for the new graduate. PMID- 6914304 TI - After graduation, consider a mentor. PMID- 6914299 TI - An elastase-specific inhibitor from human bronchial mucus. Isolation and characterization. AB - It was shown previously that human bronchial mucus contains an acid-stable proteinase inhibitor directed against trypsin and chymotrypsin, polymorphonuclear granulocyte elastase and cathepsin G. In addition to this well-characterized inhibitor, designated here as BSI-ATE (identical with the inhibitor HUSI-I from human seminal plasma or antileucoprotease), another acid-stable inhibitor BSI-E is present in the mucus which exerts inhibitory activity towards porcine pancreatic and human granulocytic elastase, but not against trypsin, chymotrypsin, or granulocytic cathepsin G. This elastase-specific inhibitor was isolated by affinity chromatography. Its molecular mass and its amino acid composition are very similar to those of BSI-TE. An immunological cross reactivity between both inhibitor species was not observed. In the mucus of patients suffering from obstructive airway disease the elastase-specific inhibitor is not present in the free form but can be liberated by acidification. PMID- 6914306 TI - My most unforgettable patient. PMID- 6914307 TI - The trash can blues. Environmental health issues related to waste disposal: its history, management and implications for nursing. PMID- 6914308 TI - Toxic wastes: a challenge for nurses. PMID- 6914309 TI - Plan for success: preparing for the 1982 State Boards. PMID- 6914312 TI - [Nutrition education in schools in the European Economic Community countries. Various biomedical, economic, family and social aspects in France]. PMID- 6914310 TI - Suggestions for change in nursing education: a student's view. PMID- 6914311 TI - [Colonoscopy]. PMID- 6914313 TI - [Renal scintigraphy]. PMID- 6914314 TI - [The psychiatric nurse: obsessional neurosis]. PMID- 6914315 TI - [Prostitution in France]. PMID- 6914316 TI - [Frame of reference with a view to an education program for nurses in Community health]. PMID- 6914317 TI - [A milligram of reflexion on medications: concrete actions. IV]. PMID- 6914318 TI - [Menopause]. PMID- 6914320 TI - [The advisory council of the hospital staff]. PMID- 6914319 TI - [I administer penicillins]. PMID- 6914321 TI - [Traumatic amputation]. PMID- 6914322 TI - Inhibition of porcine elastase II by chicken ovoinhibitor. AB - Interaction of porcine elastase II with native and modified chicken egg-white ovoinhibitor was studied by determining the residual activity of the partially inhibited enzyme and by direct measurement of the stoichiometry of interaction using affinity chromatography, electrophoresis and gel filtration. It was found that the chymotrypsin binding site that is not modified by mild oxidation with N chlorosuccinimide (Shechter et al., Biochemistry, (1977) 16, 992-997) is capable of binding elastase II as well. The binding of chymotrypsin and elastase II is mutually exclusive and the affinity of chymotrypsin is stronger. Binding of 2 mol trypsin as 1 mol elastase I by ovoinhibitor does not interfere with the binding of elastase II. There is also an indication that the second binding site for chymotrypsin is capable of forming a complex with an additional molecule of elastase II, but the binding is so weak that it could be detected only by electrophoresis. PMID- 6914323 TI - Encountering reality: reactions of newly hired R.N.'s to the world of the medical center. PMID- 6914324 TI - Variables important in the selection of New Zealand nurses: implementation and evaluation of a multivariate selection technique. PMID- 6914325 TI - Role, selection and preparation of unit head nurses--III. PMID- 6914326 TI - An investigation of the influences of selected factors on nurses' inferences of patient suffering. PMID- 6914327 TI - The assessment of patients' need for nursing care on geriatric wards. PMID- 6914328 TI - The role of the health visitor in a psychiatric team. PMID- 6914331 TI - Contingency plan to meet an acute health visitor shortage in Thanet, Kent. PMID- 6914330 TI - A health profile of homeless vs non-homeless families in Central London. PMID- 6914329 TI - The Calderdale immunization project. PMID- 6914332 TI - Preparing children for school. PMID- 6914333 TI - Supporting the schoolchild with eczema. PMID- 6914334 TI - Helping children at a local progress clinic. PMID- 6914335 TI - Education and training for school nursing. PMID- 6914336 TI - School nursing in Guernsey. PMID- 6914337 TI - Know your organizations: the Child Growth Foundation. PMID- 6914338 TI - The decreased stimulatory activity of hemin for globin synthesis at high concentrations of potassium salts in a rabbit reticulocyte lysate system. AB - The effect of various concentrations of hemin on globin synthesis was studied at various concentrations of potassium salts using a rabbit reticulocyte lysate system. The optimal concentration of hemin for globin synthesis was 10-30 microM at 100 mM and 200 mM K+. When the concentration of potassium salts was changed, globin synthesis without added hemin was optimal at 200 mM K+ or at 160 mM K+ and 60 mM Cl- and the globin synthesis at higher concentrations of potassium salts was similar to that at the optimal concentration of hemin. Using rabbit reticulocyte lysate, the binding of [35S]Met-tRNAf to the 40S ribosomal subunits was compared with that at the optimal concentration of added hemin. It was found that the binding without added hemin was inhibited greater at 100 mM KOAc than at 200 mM KOAc. But, a high concentration of hemin inhibited the binding at both KOAc concentrations. The postribosomal supernatant of the lysate was preincubated at various concentrations of KOAc and the inhibitory activity of the supernatant was measured in the lysate globin synthesis system. The data suggested that so called "hemin-controlled translational inhibitor" was slowly formed and less active at the high KOAc concentration. Therefore, it is also suggested that stimulation of globin synthesis and Met-tRNAf binding to 40S ribosomal subunits in hemin-deficient lysate are due to the slower formation of HCI and the lower activity of HCI at a high K+ concentration. On the basis of these observations, 1) the different requirements of hemin for globin synthesis between reticulocytes and their lysates and 2) a possible physiological meaning of the findings are discussed. PMID- 6914339 TI - Work smarter - not harder - with time management. PMID- 6914341 TI - The centralized education and nursing departments: collaboration or collision? PMID- 6914342 TI - Methods of teaching - revisited the incident process. PMID- 6914340 TI - Nurses' writing blocks. PMID- 6914343 TI - Through the eyes of continuing education - Greece. PMID- 6914346 TI - Symposium: the role of the gerontological nurse specialist in various in-patient settings. PMID- 6914345 TI - Group experiential learning in adult education. PMID- 6914344 TI - Using survey research methodology: an examination of one project. PMID- 6914348 TI - Role of the gerontological clinical nurse specialist at Whittier Hospital. PMID- 6914347 TI - Gerontological clinical nurse specialist at UCLA--where to begin? PMID- 6914349 TI - Role of the geriatric nursing program coordinator at a Veterans Administration Medical Center. PMID- 6914351 TI - A pioneer gerontological nurse specialist in a community hospital setting. PMID- 6914350 TI - Role of the nursing coordinator on a geropsychiatric unit. PMID- 6914352 TI - Symposium: the role of the gerontological nurse specialist in various in-patient settings--discussion. PMID- 6914353 TI - [Determination of inorganic phosphorus on the (Cobas) Bio (direct method without deproteinization) (author's transl)]. AB - The direct molybdate method for the determination of inorganic phosphorus was adapted to the (Cobas) Bio centrifugal analyzer. We evaluated test characteristics such as reaction time, linearity range, accuracy and precision within series and from day to day. Accuracy was checked using control sera, three different types of recovery experiments, and by experiments running in parallel. Because the results of the determination of inorganic phosphorus depend greatly on the method and the procedure used (with/without deproteinization), we checked the accuracy not only by experiments running in parallel, but by comparison with the following methods: the malachite green method without and with two different techniques for deproteinization, the molybdate/p-methylaminophenol sulfate method with and without deproteinization, and the molybdate/vanadate method with deproteinization. Using patients' sera as well as control sera, it was shown that the preferred molybdate method gave, within the normal range of errors, the same results as the malachite green method without deproteinization. PMID- 6914354 TI - [The identification and nursing care of the high-risk pregnancy]. PMID- 6914355 TI - [Care of a pre-eclampsia multipara with repeated pregnancy loss]. PMID- 6914356 TI - [Heart disease and nursing care during pregnancy]. PMID- 6914358 TI - [Adolescent pregnancy and nursing care]. PMID- 6914357 TI - [Nursing care of the mother with placenta previa]. PMID- 6914361 TI - [The nonstress test]. PMID- 6914360 TI - [The developmental awareness of object constancy in early infancy]. PMID- 6914359 TI - [Postterm pregnancy - implications for mother and infant, challenge for the nurse]. PMID- 6914362 TI - [Breast milk jaundice]. PMID- 6914363 TI - [Nursing care of the patient with choriocarcinoma]. PMID- 6914364 TI - [Manifestations of passive and active behaviors in a radical hysterectomy patient]. PMID- 6914365 TI - [A suggestion about the time of taking patient's body temperature]. PMID- 6914367 TI - The role of the nurse executive. AB - It is vital that the nurse executive critically examine her role conception and her role performance. She should take an activist's position in regard to her role, making it the sort of role it should be rather than merely filling the role as others expect or anticipate. Every role has much elasticity in it, and this enables the nurse executive to manipulate and alter the role if she tries. She also should learn to be sensitive to attempts to cast her in lesser roles than those which accord with her position in the organization. Role is an excellent concept by which to consider and link such various elements of management as managerial skills and abilities, managerial functions, organizational status, and strategies for management. PMID- 6914366 TI - [Survey of injection therapy in hospital]. PMID- 6914368 TI - Implementing a competency-based orientation program. AB - Competency-based orientation is efficient and effective. It allows individual learning needs to be met without sacrificing achievement of consistent standards. The system does require a large initial investment in the development of learning options and assessment of evaluation tools. It also requires the commitment of nurse managers and administrators to the concept and the implementation process. Orientation is still complex and expensive at Maryland General, but now it meets individual needs and is cost-effective. PMID- 6914369 TI - Unifying education and practice: one medical center's design. Part 2. PMID- 6914370 TI - Research in practice: a process of collaboration and negotiation. AB - Because practice-research conflicts confront nurses and investigators in clinical settings, our department of nursing research section found the need for collaboration and negotiation to be the major characteristic of practice setting research. Moreover, in the process of collaboration and negotiation, a number of problems arise for which alternative solutions need to be considered and tried. These problems include risk taking, vested interest, the rights of research subjects, and the need to produce both scientific and practical knowledge. The challenges faced when conducting research in practice settings are only partially predictable and only partially resolvable, but they are always exciting. The potential contributions are considerable since the basic challenge is to produce relevant, accurate information for immediate practice decisions, as well as to construct design and analysis methods that allow the project to contribute to nursings' general body of knowledge. PMID- 6914371 TI - Using computer simulation to predict ICU staffing needs. PMID- 6914372 TI - Strengthening the top-level management team. PMID- 6914373 TI - Introducing the "Patient Care Information System". PMID- 6914374 TI - An educational forum for primary nurses. PMID- 6914375 TI - Law for leaders. "No Code" orders: current developments and the nursing director's role. PMID- 6914377 TI - Moving toward interdependence: strategies for collaboration. PMID- 6914376 TI - Research policy for nursing services: Part 1. PMID- 6914378 TI - Characteristics of a professional nursing practice climate: a survey. PMID- 6914380 TI - Nursing documentation: a format not a form. AB - Nurses have a difficult time committing themselves to the documentation of patient care. Various forms, assessment sheets, and checklists have been created only to prove ineffectual or to be discarded. Our format allows for the documentation of health status and permits nurses to document in the style with which they are most comfortable. The format is designed to elicit critical information and to reflect the hospital's established nursing practice standards. Subjective and objective evaluations conducted over a three month period demonstrated an appreciation for the format, a marked increase in nursing documentation, and a strong commitment by the nursing staff to reflect nursing practice in nursing documentation. A format not a form-is a method that has proven successful. PMID- 6914382 TI - Nurse-physician collaboration: a changing relationship. PMID- 6914379 TI - Can managerial performance be predicted? PMID- 6914381 TI - The delivery of human services: can program evaluation make a difference? PMID- 6914383 TI - Does joint practice work? PMID- 6914385 TI - The midwife as doula: a guide to mothering the mother. PMID- 6914384 TI - Cooperation or competition? The choice is ours. PMID- 6914386 TI - Postpartum early discharge: an inner city experience. PMID- 6914387 TI - The training of auxilliary nurse-midwives in Afghanistan. PMID- 6914388 TI - Swimming and physical fitness during pregnancy. PMID- 6914389 TI - Nonsteroidal anti-inflammatory agents--Part II. PMID- 6914390 TI - Headache: understanding your patients' most common complaint. PMID- 6914391 TI - Dealing with the disturbed patient: tools for nursing intervention. PMID- 6914392 TI - Ethical issues in nursing: your responses to JPN's fourth annual survey. PMID- 6914393 TI - Rooting out reality shock: how to prepare your students for the "real world" of nursing. PMID- 6914394 TI - Climbing the career ladder from LP/VN to RN. PMID- 6914395 TI - A positive approach to clinical evaluation. PMID- 6914396 TI - What should practical nurses be able to do? PMID- 6914398 TI - Refined crystal structure of gamma-chymotrypsin at 1.9 A resolution. Comparison with other pancreatic serine proteases. PMID- 6914397 TI - Are LP/VNs equipped to be geriatric nurses? PMID- 6914399 TI - [Effects of C3 nephritic factor on the complement system--with special reference to stabilizing effect on C3 convertase (C3bBb) activity (author's transl)]. PMID- 6914400 TI - Property of kinin-forming enzyme in rat stomach. AB - The effects of inhibitors on the kinin-forming enzyme (KFE) activity in the rat stomach were investigated at pH 4.8. The KFE activity was unaffected by trasylol (200 KIU/ml), soybean trypsin inhibitor (100 microgram/ml) and p-tosyl-L-lysine chloromethyl ketone (10-3 M), but was inhibited by pepstatin A (10(-6) M) and chymostatin (1.5 x 10(-4) M). Each product from the rat plasma kininogen by the rat stomach KFE and the bovine spleen cathepsin D was eluated at the same retention time on the equilibrium chromatography on the SP-Sephadex C-25 column. The KFE activity in the rat stomach was considerably high compared with that in various regions of the intestine. These results suggest that the KFE is characteristically similar to cathepsin D, and the enzyme is probably relevant to the function of the stomach. PMID- 6914402 TI - Career articulated nursing education: an overview of Stormont-Vail School of Nursing. PMID- 6914401 TI - The Equal Rights Amendment: a matter of simple justice. PMID- 6914403 TI - The advanced registered nurse practitioner. PMID- 6914405 TI - Academia in Maryland: controversy--educational preparation for registered nurses. PMID- 6914404 TI - New in health: pneumococcal vaccine. PMID- 6914406 TI - Law and the nurse. PMID- 6914408 TI - Health care cuts discussion. PMID- 6914407 TI - Law and the nurse: contractural obligations arising from the employer/employee relationships. PMID- 6914409 TI - Health care cuts discussion. PMID- 6914411 TI - Stress and the nurse. PMID- 6914410 TI - The ultimate weapon - should nurses use it? PMID- 6914412 TI - The disabled and the nurse. PMID- 6914413 TI - The disabled and the nurse: continuous ambulatory peritoneal dialysis. PMID- 6914414 TI - The health dimensions of waste disposal. PMID- 6914415 TI - Rewards in nursing: case in point "nurse preceptors". PMID- 6914416 TI - 1 out of 44. PMID- 6914417 TI - What's your paycheck worth? PMID- 6914418 TI - Comparable worth. PMID- 6914421 TI - The investigation of male and female infertility. PMID- 6914422 TI - Why is it hard to lose weight. PMID- 6914420 TI - Problems in health care for the aged universal. PMID- 6914419 TI - The corporate health care system and the contraindications to good health. PMID- 6914423 TI - The effects of perinatal death. PMID- 6914424 TI - Episiotomy--indications, technique and results. PMID- 6914425 TI - Attitudes to breast feeding. PMID- 6914428 TI - The evolution of thought in obstetrics. PMID- 6914426 TI - Examination of the newborn. PMID- 6914427 TI - Normal development in adolescence. PMID- 6914429 TI - Birth centre meeting. PMID- 6914430 TI - The challenge of sexually transmitted diseases. PMID- 6914431 TI - Breast feeding the adopted baby. PMID- 6914433 TI - Patient compliance. PMID- 6914432 TI - The growth and development of children following maternal hypertension in pregnancy. PMID- 6914434 TI - The treatment of male and female infertility. PMID- 6914435 TI - Are post-natal support groups necessary? PMID- 6914436 TI - Dental services in the community. PMID- 6914437 TI - Maternal age in the incidence of pre-term and small-for-dates babies. PMID- 6914440 TI - The hazards and management of twin pregnancies. PMID- 6914439 TI - The present state of midwifery training. PMID- 6914438 TI - Child-rearing and lone fathers. PMID- 6914441 TI - Changing patterns of children's growth: the need for vigilance. PMID- 6914442 TI - The corticosteroids. PMID- 6914443 TI - A violent society -- is there a solution? PMID- 6914444 TI - NHS reorganization 1981-82. PMID- 6914445 TI - Psychosexual counselling -- the nurses role. PMID- 6914446 TI - A joint clinic between health visitors and clinical psychologists. PMID- 6914447 TI - The menopause -- an age for concern. PMID- 6914448 TI - Hypertensive disease of pregnancy. PMID- 6914449 TI - Juvenile diabetes. PMID- 6914450 TI - Home support for the breast feeding mother. PMID- 6914451 TI - The RCM--the first 100 years: where are we now? PMID- 6914452 TI - "Who's holding the baby now?"--Spastics Society Report on Perinatal and Neonatal Mortality. PMID- 6914453 TI - [No life without kallikrein]. PMID- 6914454 TI - Primary nursing fully implemented at Miriam. PMID- 6914456 TI - Continuing education: out of the maze. PMID- 6914455 TI - Yes: professional liability insurance is needed by professional nurses practicing in insured hospitals. PMID- 6914457 TI - Infection Control Nurses Association symposium. PMID- 6914458 TI - Implementing the nursing process in operating theatres. PMID- 6914459 TI - NATN workshop on the nursing process. PMID- 6914460 TI - Self-care: a little or a lot. PMID- 6914461 TI - Definable problems--definable plans facilitating a team approach to patient care. PMID- 6914462 TI - Functional nursing vs. primary nursing in a hemodialysis unit. PMID- 6914463 TI - Patient education as a nursing intervention for control-seeking behaviors. PMID- 6914464 TI - Legislative log: back to the drawing board. PMID- 6914465 TI - The evolution to CAPD. PMID- 6914467 TI - Plasma exchange therapy. PMID- 6914468 TI - The home hemodialysis assistant: outpatient groups. PMID- 6914466 TI - Nutrition notes: dietary sodium. PMID- 6914469 TI - Acute renal failure -- a challenge for all nurses. PMID- 6914470 TI - What effects will the proposed elimination of Network Coordinating Councils have on nephrology nursing? PMID- 6914471 TI - Professional development through involvement in CNNT. PMID- 6914473 TI - Collective bargaining: dilemma for nurse educators. PMID- 6914472 TI - Corporate nurse: it's new...but is it better? PMID- 6914474 TI - The experienced nurse and the new graduate: do their learning needs differ? PMID- 6914475 TI - The educational preparation of newly-appointed primary nurses. PMID- 6914476 TI - Practical suggestions for applying to doctoral programs. PMID- 6914477 TI - One of nursing's harder jobs. Managing the patient with liver dysfunction. PMID- 6914478 TI - Caring for the patient on intraarterial chemotherapy... are you ready? PMID- 6914479 TI - Caring for the sexually aggressive patient--you don't have to blush and bear it. PMID- 6914480 TI - Some do's and dont's for giving report. PMID- 6914481 TI - Be prepared for double trouble if your surgical patient's a diabetic. PMID- 6914482 TI - The ins and outs of administering I.V. bolus injections. PMID- 6914484 TI - Lawyer on call: exactly what does your malpractice insurance dollar buy? PMID- 6914483 TI - Reyes syndrome. PMID- 6914485 TI - Sharing: Miss Spencer's way. PMID- 6914486 TI - Nursing in the '90s: autonomy and high morale...and about time, too. PMID- 6914487 TI - Medication error: clarify laboratory test results given by telephone. PMID- 6914488 TI - Knowing what you hear: a guide to assessing breath and heart sounds. PMID- 6914489 TI - Assessing breath sounds. PMID- 6914491 TI - Grieving families: let your heart do the talking. PMID- 6914490 TI - Assessing heart sounds. PMID- 6914492 TI - What's a continent ileostomy? When Karen found out, so did we. Nursing grand rounds. PMID- 6914493 TI - All thingss change... including nursing. PMID- 6914494 TI - Your patient's angry--what should you do? PMID- 6914495 TI - A life-and-breath nursing challenge: helping patients who must stop smoking. PMID- 6914496 TI - Value for money. PMID- 6914497 TI - Guy's health district. PMID- 6914498 TI - The 35-hour week--friend or foe? PMID- 6914499 TI - Back to the bedside. PMID- 6914500 TI - Some current thinking on job satisfaction. PMID- 6914501 TI - Vitamin C and anaemia--news from Sweden. PMID- 6914502 TI - Regional close-up: Oxford region. PMID- 6914503 TI - The crisis in nurse education. PMID- 6914504 TI - The new structure of the NHS. PMID- 6914505 TI - A return to the classical model of the curriculum? PMID- 6914506 TI - The role of the nursing officer. 1. PMID- 6914507 TI - Developing teaching skills. PMID- 6914508 TI - Regional close-up: North West Thames. PMID- 6914509 TI - The dynamics & management of burnout. PMID- 6914510 TI - Patient education programs. PMID- 6914511 TI - Public law 93-360. PMID- 6914512 TI - Perspectives in nursing: guilt by association? PMID- 6914513 TI - Art and science of management: theft: side effect of burnout. PMID- 6914514 TI - Resource team: a staffing solution. PMID- 6914515 TI - Patient classification: an effective management tool. PMID- 6914516 TI - An inactive nurse returns to work. PMID- 6914517 TI - Participative management. PMID- 6914518 TI - Implementing the clinical nurse specialist role: a success story. PMID- 6914519 TI - The nursing service administrator. PMID- 6914520 TI - Focus: on the AHA's Commission on Nursing: nursing shortage. PMID- 6914523 TI - Computers: bringing nursing service "on-line". PMID- 6914524 TI - COPD patient teaching program. PMID- 6914521 TI - Law for the nurse manager: nursing assessment. PMID- 6914525 TI - Nurses' clinical judgments. PMID- 6914526 TI - Developing a primary nurse. PMID- 6914522 TI - Law for the nurse manager: malpractice insurance. PMID- 6914527 TI - Nurse day. PMID- 6914528 TI - Mandating continuing education: is there a better way? PMID- 6914529 TI - Instant problem solving. PMID- 6914530 TI - Patient education on a shoestring budget. PMID- 6914531 TI - Reversing the turnover trend. PMID- 6914532 TI - Art & science of management: one to one. PMID- 6914533 TI - Focus: on bending the rules: a view from the field. PMID- 6914534 TI - Standing tall: what's right about nursing. PMID- 6914536 TI - It's a family affair: medical center has 24-hour daycare. PMID- 6914535 TI - Angel of Mercy syndrome clouds romance, marriages. PMID- 6914537 TI - Financial nurse: understand your compensation package. PMID- 6914538 TI - Doctors vs Nurses: is anybody winning? PMID- 6914539 TI - Vignettes from Mt. Edgecumbe, Alaska: challenge, concern, affection. PMID- 6914540 TI - Questionnaire measures "value and relevance" of CE. PMID- 6914541 TI - Dawn of a new age. PMID- 6914542 TI - Legal nurse: should nurses become lawyers. PMID- 6914543 TI - Taking baby to work: a look at day nurseries. PMID- 6914544 TI - One environment--different sickness rates. PMID- 6914545 TI - International. USSR: publicity for union push on working conditions. Poland: 'health leave' for those exposed to work hazards. PMID- 6914546 TI - The role of the OH nurse. PMID- 6914547 TI - Safety: using animal tests to detect human carcinogens. PMID- 6914549 TI - Adolescent sexuality: use of a questionnaire for health teaching and counseling. PMID- 6914548 TI - Nurse practitioner guidance for the adoptive family from birth to adolescence. PMID- 6914550 TI - The new federalism and health care. PMID- 6914551 TI - Nurses' exchange: the paper doll technique. PMID- 6914552 TI - Pediatric management problems: genu valgum and intoeing gait. PMID- 6914554 TI - Educational preparation for nursing - 1980. PMID- 6914553 TI - [Kallikrein-kinin system in children with generalized forms of meningococcal infection]. PMID- 6914555 TI - Curriculum design for associate degree nursing programs: two challenges: implementing a conceptual framework and pre- and post-clinical conferences. PMID- 6914556 TI - Issues in collective bargaining for nurses. PMID- 6914558 TI - Scholarships and loans for beginning education in nursing. PMID- 6914557 TI - Faculty evaluation in higher education. PMID- 6914559 TI - Challenges--stepping stones to success. PMID- 6914560 TI - New success roles for nursing administrators. PMID- 6914561 TI - Program articulation: what it is and what it is not. PMID- 6914562 TI - Responsibility and accountability, analyzed. PMID- 6914563 TI - The legislative task force: a method to increase nurses' political involvement. PMID- 6914564 TI - Establishing a nursing legislation subcommittee. PMID- 6914565 TI - Teaching nursing in China--an exchange program. PMID- 6914566 TI - Nursing pride. PMID- 6914567 TI - Systems of life No 83. Systems and signs: reproductive system - 4. Female (contd). PMID- 6914568 TI - The pre-nursing course: a development in the sixth-form curriculum for girls 1939 69. PMID- 6914569 TI - Nursing degrees: the best of both worlds or neither? PMID- 6914570 TI - Time to stand up to unions. PMID- 6914571 TI - 'I'm getting better, but I don't know why.'. PMID- 6914572 TI - Four mental hospitals revisited--1. A decade of change. PMID- 6914573 TI - The whistle-blowers. Interview by Cherrill Hicks. PMID- 6914575 TI - Children in hospital--5. Organisation of nursing duties and training. PMID- 6914576 TI - Are enemas necessary? PMID- 6914574 TI - Theatre nursing care study: abdominal hysterectomy. PMID- 6914577 TI - The problems of grief and separation in the special care baby unit. PMID- 6914578 TI - Care is relatives. PMID- 6914579 TI - Keeping Poland's lifeline open. PMID- 6914580 TI - A new approach to sick children's nursing. PMID- 6914581 TI - Those damn statistics. PMID- 6914582 TI - In defence of the tutors. PMID- 6914583 TI - Caught in a culture conflict. PMID- 6914584 TI - The heart of the matter. PMID- 6914585 TI - Lifting and moving patients. 1. An investigation and commentary. PMID- 6914586 TI - Community nursing care study: pleural effusion followed by empyema. PMID- 6914587 TI - Four mental hospitals revisited--2. Farleigh--from a control role to a care role. PMID- 6914588 TI - Mapperley Hospital learners' survey. PMID- 6914589 TI - Crisis intervention in the problems of a pre-school diabetic child. PMID- 6914590 TI - The good intention. PMID- 6914591 TI - The buck stops here. PMID- 6914593 TI - The Joint Board - some background figures. PMID- 6914592 TI - Teaching the skills of nursing communication. PMID- 6914595 TI - Continuing education: an essential to nursing strategy in primary health care. PMID- 6914594 TI - Wound care No. 3. Healing: the normal mechanism - 1. PMID- 6914597 TI - A new face at the Rcn. Interview by Jane Salvage. PMID- 6914596 TI - Private and proud of it. PMID- 6914598 TI - Putting the new in Newham. PMID- 6914599 TI - The nucleus hospital maternity department. PMID- 6914600 TI - Nursing care study: the beginning of chronic disability. PMID- 6914601 TI - Four mental hospitals revisited - 3. Bridging the gap. PMID- 6914602 TI - Cancer in America: the socialization and promulgation of the mystique. PMID- 6914603 TI - Every nurse as researcher: an argumentative critique of principles and practice of nursing. PMID- 6914605 TI - Rethinking nursing diagnosis. PMID- 6914604 TI - The adventures of Joey in Patientland a futuristic fantasy. PMID- 6914606 TI - Toxic shock syndrome. PMID- 6914607 TI - Loss of a pet: significance to the owner, implications for the nurse. PMID- 6914608 TI - Thoughts for a friend. PMID- 6914609 TI - Off the record: home or hospital? PMID- 6914610 TI - Let's see action! PMID- 6914611 TI - Child development--1: vital beginnings. PMID- 6914612 TI - Epidemiology 4--are we doing our best? PMID- 6914615 TI - The 0-5 year old mentally handicapped child. 2. Mental retardation: causes and effects. PMID- 6914614 TI - Uniforms in psychiatry: black stockings and frilly caps? PMID- 6914613 TI - Community health councils: forward thinking. PMID- 6914616 TI - Students' forum: let's look at a problem. Infectious hepatitis. PMID- 6914617 TI - Acromegaly: a change in size. PMID- 6914618 TI - Very low birthweight infants. 1. Striving for quality. PMID- 6914620 TI - Nursing care study. Long stay psychiatric patient: Jenny through the spy-hole. PMID- 6914619 TI - Nursing care study. Glaucoma/cerebral thrombosis: cold, half-blind and unresponsive. PMID- 6914621 TI - Picture quiz: a problem of parasites. PMID- 6914622 TI - Doctors in despair. PMID- 6914623 TI - Big is not so beautiful. PMID- 6914624 TI - The Arthur judgment. PMID- 6914625 TI - The Hippocratic oath. PMID- 6914627 TI - Every which way but forward. PMID- 6914626 TI - Where do I go from here? PMID- 6914628 TI - Visions of the ill and dying: at death's door. PMID- 6914630 TI - Child development. 4. Skipping to school. PMID- 6914629 TI - Epidemiology. 7. Making plans. PMID- 6914632 TI - Influenza: It's a cold, common killer! PMID- 6914631 TI - Unemployment and health: 'For richer, for poorer...'. PMID- 6914634 TI - Sociology: sceptics in the sluice. PMID- 6914633 TI - Nurse/patient relationships: thank you, Mr Jones (but what do you want?). PMID- 6914635 TI - Nurse education: objectively speaking. PMID- 6914637 TI - Ultrasound scanning: scanning for a midwife. PMID- 6914636 TI - Environmental causes of mental subnormality: unprotected from the outside world. PMID- 6914639 TI - New mental health act proposals: old style attitudes to be swept aside, says MIND. PMID- 6914638 TI - Nursing care study--Kawasaki disease: a disease of our time. PMID- 6914640 TI - Structuring the future. PMID- 6914641 TI - Acting on mental health. PMID- 6914642 TI - Infant crying: to cry or not to cry. PMID- 6914644 TI - Homeopathy: health from herbs. PMID- 6914643 TI - Would you call them 'scroungers'? PMID- 6914645 TI - Bereavement: time to care. PMID- 6914647 TI - Community nursing--multiple sclerosis: a credit to the family. PMID- 6914646 TI - Midwife research and training. 1. A positive contribution to practice. PMID- 6914648 TI - Students' forum--let's look at a problem: mental health. PMID- 6914649 TI - Genetic counselling: learning to keep counsel. PMID- 6914650 TI - Nursing care study--colostomy: only a temporary measure? PMID- 6914651 TI - Putting nurses on the computer. PMID- 6914652 TI - Unemployment brings ill-health omen. PMID- 6914655 TI - Move up or move out. PMID- 6914653 TI - Getting action on pay. PMID- 6914654 TI - Bold new psychiatric approach. PMID- 6914656 TI - Maternity care. 1. Our pregnant lady. PMID- 6914657 TI - NM Travel Scholarship 1980: learning from the French. PMID- 6914659 TI - The 0-5 year old mentally handicapped child. 5. Do drop in. PMID- 6914658 TI - Midwifery: bring back the midwife. PMID- 6914661 TI - Patients' advocates: from all sides. PMID- 6914662 TI - Urine bags: not to be trusted. PMID- 6914660 TI - Reorganisation: what type of units? PMID- 6914663 TI - Midwifery research and education. 2. Importance of participation. PMID- 6914664 TI - Child development. 6. Predicting the future. PMID- 6914666 TI - Traffic accident: on the road to recovery. PMID- 6914665 TI - Fenbufen: goes down well! PMID- 6914667 TI - Nursing care study - acute myocardial infarction: a return to the good life. PMID- 6914668 TI - Careers - coronary care: nursing the killer disease. PMID- 6914669 TI - Management of the patient with myocardial infarction. PMID- 6914670 TI - The role of coronary arteriography in the management of the patient with acute myocardial infarction. AB - Coronary arteriography is indicated in patients with acute myocardial infarction with complications such as ventricular septal rupture or papillary muscle rupture; when the ischemic pain recurs; or after acute myocardial infarction without major complications when information about the coronary anatomy is needed to establish prognosis and plan future therapy. Coronary arteriography after acute myocardial infarction is becoming more common as interventions such as coronary bypass surgery, streptokinase lysis of an acute thrombus, and transluminal angioplasty become more prevalent. Although arteriography has been reported to be safe, certain dangers exist and specific care must be taken to avoid them. PMID- 6914671 TI - The role of hemodynamic monitoring and circulatory assist devices in the management of the patient with acute myocardial infarction. PMID- 6914673 TI - Biliary secretion in conscious rabbits: role of the enterohepatic circulation of bile salts and of the gall bladder. AB - The role of enterohepatic circulation of bile salts in biliary secretion in conscious rabbits has been investigated before and after cholecystectomy. Bile flow was higher and bile salt concentration lower in cholecystectomized than in intact rabbits: this could have been caused by a negative feed-back effect on bile salt synthesis as the circulating bile salt pool increased. The effects of cholecystectomy on flow and bile salt concentration balanced each other. Bile flow and bile salt concentration declined after interruption of the enterohepatic circulation in both cholecystectomized and intact rabbits. Furthermore, the percentage of the flow of bile independent of bile salt secretion increased, while that independent of total analysed solutes decreased after the enterohepatic circulation was broken. These results confirm that the decrease in bile flow after interruption of the enterohepatic circulation is due to loss of bile salts and not of electrolytes. PMID- 6914674 TI - Biliary response to food in rabbits: role of the gall bladder and the enterohepatic circulation of bile salts. AB - The biliary response to feeding has been investigated in intact and cholecystectomized rabbits, with and without interruption of the enterohepatic circulation of bile salts. The relative contribution of the different secretory mechanisms involved in this process has been examined. Feeding induced an increase in the flow and bicarbonate concentration of the bile and a slight decrease in the bile salt content in rabbits with gall bladders and the enterohepatic circulation intact. Feeding with the enterohepatic circulation interrupted elicited a drop in bile flow and the bile salt concentration, but an increase in bicarbonate concentration. Interruption of the enterohepatic circulation thus dramatically modifies the feeding response: a response to food is still detectable after interruption, but is masked by the negative effects of drainage of the bile away from the duodenum. PMID- 6914672 TI - The role of digitalis in acute myocardial infarction. AB - Digitalis is useful in the control of atrial tachyarrhythmias complicating acute myocardial infarction, whether or not congestive heart failure is present. The drug can also be helpful in patients in the subacute and chronic phases of myocardial infarction if congestive heart failure is present. Digitalis is not, however, the drug of choice in the treatment of patients with left ventricular dysfunction complicating acute myocardial infarction. PMID- 6914675 TI - Quantitative aspects of preoptic thermosensitivity in the conscious ox. AB - An attempt has been made to study the quantitative relationship between the temperature of the anterior hypothalamic/preoptic (AH/PO) region and heat balance in the conscious ox (Bos taurus) at a thermoneutral air temperature of 20 degrees C. Heat balance was measured by combined gradient-layer and open-circuit calorimetry and AH/PO temperature was controlled using a water-perfused thermode. Continuous warming or cooling of the AH/PO region caused a transient heat imbalance which shifted core temperature to a new stable level dependent upon the level of stimulation. The heat balance responses to continuous AH/PO warming included peripheral vasodilation and increased respiratory and cutaneous evaporative heat loss; those to AH/PO cooling consisted mainly of decreased heat loss. Heat production was largely unaffected by both AH/PO warming and cooling. The heat balance responses developed only slowly, reaching a peak up to 50 min after the start of stimulation and taking several hours to complete. The change to stability in core temperature during continuous AH/PO stimulation and the additional heat loss prior to that stability were the most sensitive indicators of response of all the variables measured. A significant response was observed in these parameters even at the smallest stimulus level (less than 0.33 degrees C) and correlation of response with stimulus level was precise with a zero threshold for response. This suggests a continuity of operation of the AH/PO mechanism about zero. Several responses showed a curved relationship between slope of response and stimulus level, such that the increment in response per unit increase in stimulus level became greater as stimulus level increased. The results suggest a two-tier form of thermoregulation in the ox with AH/PO sensitivity to warming greater than its sensitivity to cooling. It appears also that AH/PO temperature is at least as dominant in the thermoregulatory mechanisms in the ox as it is in smaller animals. PMID- 6914677 TI - The terminations and secondary projections of myelinated and non-myelinated fibres of the aortic nerve in the cat. AB - In anaesthetized cats the projection of myelinated and non-myelinated afferent fibres of the aortic nerve to the brain stem was studied by recording antidromic potentials evoked in the nerve by electrical stimulation of the medulla oblongata. Probable sites of termination of both myelinated and non-myelinated afferent fibres were found to be in the ipsilateral medial lateral subnucleus of the nucleus tractus solitarius, the ipsilateral area postrema, the commissural nucleus and the contralateral nucleus tractus solitarius about the level of the obex. No evidence for a projection of primary afferent fibres in the aortic nerve to the medial reticular formation was found. In a second series of experiments the aortic nerve was electrically stimulated and extracellular recordings were made from neurones in the medulla activated by afferent fibres in this nerve. Neurones activated by myelinated afferent fibres were located in the nucleus tractus solitarius, dorsal vagal motor nucleus, commissural nucleus, area postrema and lateral reticular formation including nucleus ambiguus. Neurones activated by non-myelinated afferent fibres were in or near the medial nucleus tractus solitarius, the area postrema, dorsal motor vagal nucleus and nucleus intercalatus. Few neurones appeared to be activated by both myelinated and non myelinated afferent fibres and they were located in the medial nucleus tractus solitarius and nucleus ambiguus. PMID- 6914676 TI - The distribution in the cat brain stem of neurones activated by vagal nonmyelinated fibres from the heart and lungs. AB - In anaesthetized cats, right cardiac vagal branches were electrically stimulated and recordings of evoked 'slow wave' and single neurone activity were made in the brain stem. Short-latency 'slow wave' and multi-neuronal activity evoked by excitation of myelinated vagal afferent fibres were recorded in the medial and lateral subnuclei of the nucleus tractus solitarius, the area postrema, the dorsal vagal motor nucleus, the lateral reticular formation and the nucleus ambiguus. Long-latency responses evoked by vagal non-myelinated fibres were recorded in the medial subnucleus of the nucleus tractus solitarius, the area postrema, dorsal vagal motor nucleus, the parahypoglossal area and the lateral reticular formation dorsal to the nucleus ambiguus. A specific study was made of seventy-two single neurones activated by non-myelinated afferent fibres in the cardiac branch. Thirty-four were shown to be synaptically activated, twenty-one were activated nonsynaptically and seventeen could not be classified. One neurone was also activated by myelinated cardiac afferent fibres, and two by thoracic vagal (including pulmonary) afferent fibres. Neurones were not spontaneously active. Indirect evidence suggests that the majority of the recordings of nonsynaptically activated neurones were likely to be from cell bodies. Neurones were located from the level of the obex to 3.0 mm rostral to it in the medial subnucleus of the nucleus tractus solitarius (45), and in the lateral subnucleus (2), the area postrema and its border with the medial subnucleus of the nucleus tractus solitarius (13), the dorsal vagal motor nucleus (9), the parahypoglossal area (1) and the lateral reticular formation dorsal to nucleus ambiguus (2). Recordings were made from fifteen neurones activated by myelinated fibres in the cardiac vagal branches, and twelve were excited synaptically. The neurones were located in the medial (8) and lateral (3) subnuclei of the nucleus tractus solitarius, the dorsal vagal motor nucleus (1) and the lateral reticular formation (1). Four neurones were also excited by vagal afferent fibres in the thoracic vagal nerve immediately caudal to the caudal cardiac branch. PMID- 6914678 TI - Diuresis from stimulation of left atrial receptors: initial purification steps from plasma of the causative agent. AB - This paper reports the initial purification steps of a humoral agent which may mediate the diuresis resulting from stimulation of left atrial receptors in anaesthetized dogs. The agent was shown to be stabilized in plasma by acidification to pH 3.2. Acid acetone precipitation was found to be a convenient method as a first stage in the purification of the humoral agent in plasma. Heat stability studies showed that the agent was stable in acidified plasma for up to 20 min of heating in a boiling water bath. Precipitation of plasma proteins under these conditions made this another possible first stage in the purification of the agent in plasma. Some general conclusions about the possible nature of the humoral agent are discussed. PMID- 6914679 TI - Rapid cerebral vasodilatation in brief hypoxia in anaesthetized animals. AB - In anaesthetized dogs, cats and rabbits, intracranial pressure was measured continuously during brief or transient hypoxia, induced by (a) lowering inspired O2 to 9--10% for 2--3 min, or (b) giving 2--3 breaths of nitrogen. In almost all instances there was an increase in i.c.p. which started in less than 20 s; this occurred with either spontaneous or controlled ventilation, and whether or not there was also a rise in arterial blood pressure; the time course was similar to that of the arterial chemoreceptor reflex responses of ventilation and blood pressure. Division bilaterally of the sinus and vagus nerves in six cats showed that the intracranial pressure response was not dependent on these chemoreceptor afferent pathways. The results suggest a rapid vasodilatation starting at a time when cerebral arterial oxygen tension is unlikely to be below 7 kPa (50 mmHg). The mechanism remains unexplained. PMID- 6914680 TI - The influence of intravenous glucose on body temperature. AB - The influence of an intravenous infusion of glucose (500 ml of 20% w/v), on heat production and variables which contribute to heat loss was studied in six normal human volunteers. Mannitol (500 ml of 20% w/v) was infused on a different occasion as an osmotic control. Both infusions produced changes in haematocrit and osmolality of a similar magnitude. Heat production increased by 20% after intravenous glucose but only a small increase in heat production was observed after intravenous mannitol. Calf blood flow increased after both infusions but hand blood flow increased only after the glucose infusions. The increase in skin temperature which was observed after both infusions was associated with increases in peripheral blood flow. Core temperature decreased slightly following administration of both substances. The changes in metabolic heat production and cardiovascular function are discussed. These changes do not appear to be due to the catecholamine response to hyperglycaemia and hyperosmolality. PMID- 6914681 TI - An unusual synaptic response mediated by a serotonin neurone. AB - Impulse activity in an identified serotonin-containing neurone produces a delayed slow excitatory response in another identified neurone. An axon of the serotonin neurone passes very close to the follower neurone perikaryon. The synaptic response is frequently accompanied by oscillations of the membrane potential. Constant-current pulsing experiments suggest that it could result from a reduction in membrane conductance. The response is markedly voltage-sensitive, being greatly reduced at potentials in excess of about -55 mV. Serotonin, locally applied, produces a very similar effect. The response to serotonin does not involve a change in conductance to either Na+ or Cl-, but Ca2+ appears to be involved, either by virtue of its influence on K+ conductance, or directly in its transfer of charge across the membrane. PMID- 6914682 TI - Some effects of diet on the mitotic index and the cell cycle of the ruminal epithelium of sheep. AB - The mitotic index of the ruminal epithelium increased rapidly when the diet of sheep was changed from one based on roughage to a concentrate-based diet. After several days the mitotic index declined to a new level which was slightly higher than that observed initially. Autoradiography of sections of rumen epithelium was used to construct percent labelled mitoses curves, from which the duration of the phases of the cell cycle was determined. The duration of the cell cycle was about 24 hr but decreased to 17 hr when cell proliferation was stimulated by changing the diet of the sheep from roughage to concentrate. The decrease in cell cycle time was mainly the result of the decreased duration of the phase of DNA synthesis (S phase). Data obtained from measurement of the cell cycle, together with the labelling index, were used to calculate the turnover times of the basal cell layer, and to estimate 'turnover' times for the entire epithelium. The mean turnover time for the epithelium was 16.5 days when sheep were fed a roughage based diet, 10.9 days when fed a concentrate basal diet and 4.3 days when the sheep were in transition between the roughage and the concentrate diets. PMID- 6914683 TI - An experimental approach for evaluation of the O2 balance in local myocardial regions in vivo. AB - Quantitative evaluation of myocardial oxygen balance can be accomplished by measurement of oxygen supply, demand, and intracellular oxygen concentration. Experimentally, these parameters are often related to coronary blood flow, cardiac contractility, and mitochondrial NADH redox level, respectively. Methods were developed to measure these three parameters in a local region on the myocardial surface in open-chest dogs. Local coronary blood supply was measured with the aid of a small surface thermistor, and cardiac work with a miniature strain gauge arch. NADH oxidation--reduction state was recorded using surface fluorometry through a fibre optic light guide. Transient anoxia produced by nitrogen breathing caused a rapid but reversible elevation in NADH levels, which was not always accompanied by a concomitant change in contractile force. Elevation of heart rate resulted in a rise in intramitochondrial NADH followed by an increase in coronary flow. In spite of the increased flow, NADH levels remained elevated, indicating a change in the O2 balance; this may indicate that autoregulation does not necessarily result in total compensation. PMID- 6914684 TI - Fluid and electrolyte excretion in sheep: comparison of the effect of reduced food and water intake with oestrus. AB - Food and water intake were restricted by 29% for 48 h in ovariectomized ewes, to see whether such changes could cause a pattern of water and electrolyte excretion similar to that observed during the oestrous cycle. The closest resemblance appeared in the effect on water balance and there was also a rise in sodium excretion, as at oestrus. Restriction of intake failed to duplicate the marked sodium retention or, more particularly, the persistent potassium retention which follow natural oestrus. Restriction of food alone produced changes less similar to those seen at oestrus, mainly because this treatment caused a large increase in urine output. The similarity between the effects of restriction and 'fasting natriuresis' is discussed, with particular reference to the mildness of the stimulus in these experiments. Indications that the gut may be as important as the kidney in the regulation of salt and water balance are discussed in relation to other herbivores and to man. PMID- 6914685 TI - Degeneration and regeneration of the olfactory epithelium after olfactory bulb ablation in the pig: a morphological and electrophysiological study. AB - The olfactory bulbs were removed surgically from Large White male and female pigs, 10--12 weeks of age. At intervals of 3, 7, 14, 42 and 84 d after bulbectomy, the pigs were sacrificed and portions of olfactory mucosa were removed from the ethmoturbinate and septum regions of the nasal cavity; olfactory mucosa was also removed from unoperated pigs. A piece of each tissue sample was processed for light microscopy. The remaining tissue was placed in Ringer-Locke solution, saturated with O2/CO2 at room temperature, and the electrical activity of the olfactory epithelium was investigated in vitro by passing a stimulus of butyl acetate vapour over the epithelium. Slow negative potential changes (electro-olfactogram, e.o.g.) induced by butyl acetate were recorded. During the first two weeks after bulbectomy there was a rapid decrease in the height of the olfactory epithelium associated with the disappearance of the e.o.g. response. However by 42 and 84 d after bulbectomy, partial recovery of the height and some electrical activity of the olfactory mucosa had occurred. In some pigs, the insertion of a stainless steel lining over the cribriform plate to prevent any association of regenerating axons with forebrain tissue had no effect on the regenerative characteristics studied. PMID- 6914686 TI - Smoking patients: fatal burns and liability. PMID- 6914687 TI - Religious rights raised in nurse-labor dispute. Case in point: St. Anthony Hospital v. NLRB et al (655 F. 2d 1028 - Colo.). PMID- 6914688 TI - Legal case briefs for nurses. TN: calcium IV: permanent hand injury. N.J.: no forced meds for mental patients. PMID- 6914689 TI - Nurse refused to assist in abortion: demoted! Case in point: Kenny v. Ambulatory Centre of Miami (400 So. 2d 1262 - FLA.). PMID- 6914690 TI - [Convalescence: problem or solution]. PMID- 6914691 TI - [Integrated care of the patient as a bio-psycho-social unity]. PMID- 6914692 TI - [Nursing, a profession for almost everyone]. PMID- 6914693 TI - [Interview with D. Javier Aguirre; health counselor of the Vasco region. Interview by M. Victoria Sanfeliu and Angel Elis]. PMID- 6914694 TI - [Pharmacology and therapeutics. Basis of the action of drugs]. PMID- 6914695 TI - [Clinical analysis. White Series. I]. PMID- 6914696 TI - [Hospital infection]. PMID- 6914698 TI - [Nursing care of the tracheotomized patient]. PMID- 6914697 TI - [Arterial pressure]. PMID- 6914699 TI - [Nursing care. Contribution of nursing services to the identification of services offered]. PMID- 6914700 TI - [Pacemaker: study of the implantation technic and its psychological implications]. PMID- 6914701 TI - [Pharmacology and therapeutics. Causes of adverse drug reactions]. PMID- 6914702 TI - [A study on drug dependence]. PMID- 6914704 TI - [Nursing care technics. Drug administration via intramuscular route]. PMID- 6914703 TI - [Drugs as consumer products: their advertising in nonspecialized media]. PMID- 6914705 TI - [Interview with Andre Montesinos, a nurse instructor of the International Institute of Higher Education of the Intermediate Health Authorities]. PMID- 6914706 TI - [Health day by day]. PMID- 6914707 TI - [Care of the patient in coma]. PMID- 6914708 TI - [At the edge of nursing. To hear, to see and... to speak]. PMID- 6914709 TI - [Anatomy of the respiratory apparatus]. PMID- 6914710 TI - [Nursing and its nicknames]. PMID- 6914711 TI - [Guiding the nursing care process: difficulties in introduction]. PMID- 6914712 TI - [The nurse facing death]. PMID- 6914713 TI - [Present-day education in nursing]. PMID- 6914714 TI - [Clinical analyses, White Series (II): granulocyte morphology]. PMID- 6914715 TI - [Approach to the study of sex education. I and II]. PMID- 6914716 TI - [Psychological preparation of the patient before angioradiologic studies]. PMID- 6914717 TI - [Proposal for new nursing care planning]. PMID- 6914719 TI - [Maturation of the locomotion apparatus in the child]. PMID- 6914718 TI - [Physiology of the respiratory system]. PMID- 6914720 TI - [Challenge to nursing]. PMID- 6914721 TI - [Interview with Laura Padro, dietician of the Joan Rius Center]. PMID- 6914722 TI - [Approach to the study of sex education. III]. PMID- 6914723 TI - [Nursing and its image]. PMID- 6914724 TI - [Health and disease: ecological concepts]. PMID- 6914725 TI - [Pharmacology and therapeutics: cardiotonic agents]. PMID- 6914727 TI - [Quality control]. PMID- 6914726 TI - [The anonymous nurse]. PMID- 6914730 TI - [Thermoregulation: fever and its treatment]. PMID- 6914728 TI - [Where is our nursing profession going?]. PMID- 6914731 TI - [Child hospitalization]. PMID- 6914729 TI - [Contraceptive methods]. PMID- 6914732 TI - [Cardiorespiratory emergency; a program for putting into effect a cardiorespiratory emergency plan in a 300-bed hospital]. PMID- 6914733 TI - [Drainage in abdominal surgery]. PMID- 6914734 TI - [Hospital infection]. PMID- 6914735 TI - [Nursing care process]. PMID- 6914736 TI - [Rights of the patient]. PMID- 6914738 TI - [Conflict and its types]. PMID- 6914737 TI - [Continuing education for nurses in Europe: the current situation]. PMID- 6914740 TI - [Pharmacology and therapeutics. Pain treatment: analgesics]. PMID- 6914739 TI - [Hospital interference as a iatrogenic factor in the neonatal period. The function of nursing in its elimination]. PMID- 6914741 TI - [Interview with the nurses of the Central Committee of the Universidad Nacional de Enfermeria a Distancia for the standardization of curriculum]. PMID- 6914742 TI - [Nursing care; reflections on nursing service: a contribution to the identification of services rendered]. PMID- 6914743 TI - [Ministry of unemployment, disease and social insecurity]. PMID- 6914744 TI - [Points]. PMID- 6914745 TI - [Role of nursing in health centers]. PMID- 6914747 TI - [BTD (Breast Cancer Thermo Detector): a new method for detecting breast cancer]. PMID- 6914746 TI - [Nurse patient relation in the nursing care process]. PMID- 6914748 TI - [Physiopathology of the respiratory apparatus]. PMID- 6914749 TI - [Work methodology in public health]. PMID- 6914750 TI - [Diseases of the pleura]. PMID- 6914752 TI - [Proposal for a bachelor's degree in nursing]. PMID- 6914751 TI - [Primary nursing care. Experience developed in a "pilot health program"]. PMID- 6914753 TI - [General comments on bandages]. PMID- 6914754 TI - [Interview with Prof. Josef Laporte]. PMID- 6914755 TI - [The nurse and her feelings]. PMID- 6914757 TI - [Directions in nursing. Debut]. PMID- 6914756 TI - [Health knavery]. PMID- 6914758 TI - [Corticoids]. PMID- 6914759 TI - [Decubitus ulcers]. PMID- 6914760 TI - [Dehydration in the nursing infant]. PMID- 6914761 TI - [Disease as a human experience]. PMID- 6914762 TI - [Diuretics]. PMID- 6914763 TI - [The active patient: a necessary development]. PMID- 6914764 TI - [Margins in error in measuring arterial pressure with the sphygmomanometer]. PMID- 6914765 TI - [Review of the concepts of radiologic protection]. PMID- 6914766 TI - [The nurse facing safety problems in the hospital]. PMID- 6914768 TI - [He who pays is not in charge]. PMID- 6914767 TI - [Human being's leading role in his own life and death]. PMID- 6914769 TI - [Doctors and nurses: their relations]. PMID- 6914770 TI - [Hospital prophylaxis]. PMID- 6914771 TI - [Respiratory physiotherapy (I)]. PMID- 6914772 TI - [Disposable items in today's medicine]. PMID- 6914773 TI - [Directions in nursing. Night shift]. PMID- 6914776 TI - [Blueprint for the specialty of special care]. PMID- 6914775 TI - [Nursing care; reflection on nursing service: a contribution to the identification of the services rendered]. PMID- 6914777 TI - [Interview with Nelly Garzon, Prof. of the School of Nursing of the University of Colombia]. PMID- 6914774 TI - [Hospitals, systems and persons (I)]. PMID- 6914779 TI - [Nurses and congresses]. PMID- 6914778 TI - [Interview with Joaquina Ribot, President of the Board of Officers of the Gerona ATS (Association of Health Technicians) organizer of the 1st Catalan Nursing Congress]. PMID- 6914782 TI - [Directions in nursing. Marvelous world]. PMID- 6914780 TI - [Respiratory physiotherapy (II)]. PMID- 6914781 TI - [Planning nursing care for the newborn infant with neurological problems. A paper presented at the 1st Annual Meeting of the State Section on Pediatric and Neonatal Intensive Care]. PMID- 6914784 TI - [Obstetrical nursing in the regional hospital; report presented at the II Conference of the AEED]. PMID- 6914785 TI - [Epidemiology of surgical sepsis]. PMID- 6914783 TI - [Nursing care; reflections on nursing service: a contribution to the identification of the service rendered]. PMID- 6914786 TI - [Sepsis in the operating room: truth or consequences]. PMID- 6914787 TI - [Safety in electrosurgery: a continuing preoccupation]. PMID- 6914788 TI - [The operating room: an area of electrical hazards]. PMID- 6914790 TI - [Infectious complications in the endangered host patient]. PMID- 6914789 TI - [Electrical hazards in the operating room]. PMID- 6914792 TI - [Dilemma: the endangered host patient]. PMID- 6914793 TI - [Paper and soap towelettes for preventing nosocomial infections]. PMID- 6914795 TI - Infection consult. Tips and tactics to hold microbes at bay, for your patient's sake--and your own. PMID- 6914796 TI - Using local anesthesia to ease venipuncture. PMID- 6914794 TI - Sex Q & A: frank answers to your most delicate patient-counseling questions. PMID- 6914797 TI - The tragedy of fetal alcohol syndrome. PMID- 6914791 TI - [How to reduce to a minimum the risk of infection in the endangered surgical patient]. PMID- 6914798 TI - Getting those blood samples right. PMID- 6914799 TI - Mini IV patients... maximum precautions. PMID- 6914800 TI - What those breath sounds are telling you to do. PMID- 6914801 TI - As the 'RN gap' becomes a chasm LPN's move in. PMID- 6914802 TI - The fine art of giving a physical. Assessing the integumentary system. PMID- 6914803 TI - Test yourself: is this post-MI patient in trouble? PMID- 6914805 TI - Teaching patients about ultrasound and CAT brain scans. PMID- 6914804 TI - This silence we could break. PMID- 6914806 TI - Legally speaking: nursing malpractice: a giant leap in damages. PMID- 6914810 TI - Effect of trimethoprim or trimethoprim/sulphamethoxazole usage on the emergence of trimethoprim resistance in urinary tract pathogens. AB - The frequency of trimethoprim (TMP)-resistant bacteria isolated from urine was studied in hospitals, in Stockholm, Sweden, and Turku, Finland. TMP has been in clinical use in Finland since 1973, whereas in Sweden TMP was available only in combination with sulphamethoxazole (SMZ) at the time for this study. All samples were collected solely from in-patients at 4 different occasions during a 20-month period 1977-78. The frequency of TMP-resistant strains (MIC greater than or equal to 8 micrograms/ml) in Turku increased from 31 to 49%, whereas it remained at a low level (1.6-3.6%) in Stockholm during the whole period. Also the frequency of TMP/SMZ-resistant strains (MIC greater than or equal to 64 micrograms/ml) increased in Turku from 24 to 45% but remained at the same level, 0-4% in Stockholm. In Turku there was also an increased frequency of resistance to SMZ (MIC greater than or equal to 512 micrograms/ml), ampicillin (MIC greater than or equal to 32 micrograms/ml) and nitrofurantoin (MIC greater than or equal to 64 micrograms/ml), while these frequencies remained at their initial levels in Stockholm. The distribution of bacteria was different in the two areas. In Turku there was also a change towards more nosocomial strains during the observation period. Since antibacterial agents are used more frequently in Turku than in Stockholm, this might be one explanation to the increase of resistance in Turku. PMID- 6914807 TI - Sound off! Nursing's 'love it or leave it' cop out. PMID- 6914808 TI - Leadership at work. A question of black or white? PMID- 6914811 TI - [Nurse's role: ideal and reality]. PMID- 6914809 TI - Isolation and properties of a complement inhibitor from Naja haje venom, distinct from known anticomplementary factors in cobra venom. AB - A complement inhibitor (CI) has been isolated from cobra (Naja haje) venom which is distinct from the two known anticomplementary factors in cobra venom [1], in functional properties as well as structure. CI is a small (mol. wt 26,000, determined by sodium dodecyl sulphate gel electrophoresis), heat-labile glycoprotein; the amino acid composition is that of a globular protein. CI interferes at various steps of the complement sequence, including reactions of the classical and alternative pathway. No effect was observed on C4 fixation and on the assembly of the membrane attack complex from C6-9 (minor inhibiting effects, if present, have not been excluded). Initiation of the alternative pathway is inhibited by CI already at the stage of cleavage of factor B. CI binds to C4, C4b, C3 and C3b; since the major inhibitory action of CI is lost after washing of cell intermediates, complex formation and, as a consequence, steric hindrance may be responsible for the inhibiting effects of CI. CI also interferes with binding of C3b to C3b receptors on human erythrocytes. CI is non-toxic in mice when given intraperitoneally in doses of 5 microgram/g. PMID- 6914812 TI - [Nurses' exposure to cytostatics in the handling of cytostatics. Theoretical lesson and clinical study]. PMID- 6914813 TI - [Complementary tests of useful in the etiologic diagnosis of chronic diarrheas]. PMID- 6914814 TI - [Psychosomatic aspects of colonic disorders]. PMID- 6914816 TI - [From intestinal disorders to health for all]. PMID- 6914815 TI - [Crohn's disease of the colon]. PMID- 6914817 TI - [Physiology of the small intestine and of the colon]. PMID- 6914819 TI - [The adolescent and society: sociologic comments on adolescence]. PMID- 6914818 TI - [The adolescent and narcissism]. PMID- 6914821 TI - [Adolescence: disturbances of development]. PMID- 6914822 TI - [Action and the adolescent]. PMID- 6914820 TI - [Adolescence, period of transition]. PMID- 6914823 TI - [Toxicomaniac behavior]. PMID- 6914825 TI - [States of depression]. PMID- 6914824 TI - [The adolescent and his identity]. PMID- 6914828 TI - [Managing adolescents: psychiatric aid]. PMID- 6914826 TI - [Suicide]. PMID- 6914827 TI - [Anorexia nervosa]. PMID- 6914829 TI - [The "new therapies". Humanistic psychology and the human potential movement]. PMID- 6914830 TI - [The adolescent and his body]. PMID- 6914831 TI - [A disease of poor hygiene]. PMID- 6914832 TI - [Viral hepatitis in tropical zones, signs, diagnosis evolution, treatment]. PMID- 6914833 TI - [Severity of hepatitis B]. PMID- 6914834 TI - [Tropical cirrhosis]. PMID- 6914835 TI - [Primary liver cancer]. PMID- 6914836 TI - [Chronic adult hepatosplenomegalies in Africa]. PMID- 6914837 TI - [Blood plasma kallikrein-kinin system in acute intravascular hemolysis]. PMID- 6914838 TI - Team nursing to modular nursing: a planned change. PMID- 6914839 TI - [Relationship between the blood kinin system and secretory function of the stomach in patients with chronic gastritis]. PMID- 6914840 TI - Know your generics: antiparkinsonism drugs. PMID- 6914841 TI - Nurse abuse. PMID- 6914842 TI - The thromboplastic activity of lung surfactant in amniotic fluid and its application to prenatal assessment of fetal lung maturity. AB - Based on the fact that both tissue thromboplastin and lung surfactant show lamellar structures under the electron microscope and belong chemically to lipoprotein, the thromboplastic activity of lung surfactant in amniotic fluid was studied by measuring plasma recalcification time. The results obtained were as follows (1) The surfactant fractions isolated from amniotic fluid and rabbit or pig lung showed the thromboplastic activity with dose response. (2) The thromboplastic activity of amniotic fluid increased with advancing gestational age. (3) It was found that the thromboplastic activity determined by plasma recalcification time was parallel with the surfactant concentration of amniotic fluid. (4) The shortening rate of plasma recalcification time in amniotic fluid could estimate well the risk of RDS, and the critical value for RDS was assumed to be about 33%. PMID- 6914845 TI - [Registration of nurse researchers in Scandinavia]. PMID- 6914844 TI - [Nursing research--what are our prospects to get started? Prospects are diverse, although there is a certain common link, apparent from the account of conditions in the individual countries, as presented here by nurse researchers from Norway, Finland and Denmark]. PMID- 6914843 TI - [Home visits provide peace of mind and adjustment. Guidelines and home teaching of insulin-treated patients with recently diagnosed diabetes mellitus]. PMID- 6914846 TI - [Research and development within health care activities. SHSTF has held a press conference in Stockholm]. PMID- 6914847 TI - [Nursing care research initiative]. PMID- 6914849 TI - Nitrofurazone toxicity. PMID- 6914848 TI - [The adult insulin-dependent diabetic in the health care process. Theoretical observations and empirical research results]. PMID- 6914851 TI - Problems & values associated with dominance. PMID- 6914852 TI - Extrinsic factors: how they can affect a diagnosis. PMID- 6914853 TI - Cyanoacrylate adhesive for aural hematoma. PMID- 6914855 TI - Using a computed brain and orbital tomography to diagnose a brain tumor in a dog. PMID- 6914854 TI - Thoracic and vertebral osteomyelitis caused by actinomycosis in a dog. PMID- 6914856 TI - Duration of immunity in cats inoculated with a commercial feline pneumonitis vaccine. PMID- 6914857 TI - Viruria in dogs infected with canine distemper. PMID- 6914859 TI - Cervical sprain and fracture in a dromedary. PMID- 6914850 TI - Hepatic function--4: diagnosis, treatment, and management of hepatic disease. PMID- 6914860 TI - Coccidiosis in swine: effect of disinfectants on in vitro sporulation of Isospora suis oocysts. PMID- 6914858 TI - Repair of a fractured humerus in a red-tailed hawk. PMID- 6914863 TI - Pemphigus in a thoroughbred. PMID- 6914861 TI - Atypical osteomyelitis in a young bull. PMID- 6914862 TI - Preliminary tests for activity of levamisole against natural infections of eyeworms in dairy calves. PMID- 6914864 TI - Efficacy of an oral larvicide in controlling horse bots. PMID- 6914865 TI - Surgical correction of equine umbilical hernias. PMID- 6914866 TI - [Complement (C3)-activating material in synovial fluid from patients with rheumatoid arthritis]. AB - Synovial fluid from patients with the following diagnoses was investigated: - rheumatoid arthritis (RA) - rheumatoid arthritis with benign development (BRA) - osteoarthrosis (A) The sediment was isolated by ultracentrifugation, its C3 cleaving activity measured by 2-dimensional electrophoresis and its concentration if IgG, IgM, IgA, C3, C4 and C3-proactivator by immunoprecipitation. There is evidence that there is more C3 cleaving activity in RA than in osteoarthrosis. Activity levels of BRA were between those of osteoarthrosis and RA. Although there was no significant difference in the IgG-, IgM- or IgA-level of the 3 mentioned diagnoses after 21 minutes of centrifugation (133 000 g), it was possible to demonstrate more C3 breakdown products in RA than in osteoarthrosis and BRA. Very big molecules seem to be responsible for the generation of C3 cleaving products. These observations are not only of theoretical interest but seem also to be useful diagnostically. PMID- 6914868 TI - Elevated IgG and decreased complement component C3 and factor B in B-thalassaemia major. AB - Serum immunoglobulins, complements C3 and C4 and factor B were assayed in the sera of children with B-thalassaemia major, siblings and matched controls in an attempt to resolve the controversy surrounding the conflicting results reported in the literature. Significantly elevated IgG and decreased C3 and factor B levels were observed in thalassaemic patients who also had a high incidence of HBS hepatitis and other infections. The controversial results probably reflect differences in the incidence of infection, and the presence of circulating immune complexes due to blood transfusions, in the various communities. The alterations in immunoglobulin and complement levels represent a secondary rather than a primary immune disorder. PMID- 6914869 TI - ANA's economic & general welfare program: dynamics of the local unit. PMID- 6914867 TI - Codon-specific serine transfer ribonucleic acid degradation in avian liver during vitellogenin induction. AB - The relative rates of degradation of two major tRNASer species in rooster liver were simultaneously assessed during induction by estradiol-17 beta benzoate of the synthesis of a serine-rich phosphoprotein, vitellogenin. The relative rate of degradation was determined by an in vivo pulse-chase labeling method, which included a 24-h labeling period with [5-3H]orotic acid prior to and a 6-day chase period with nonradioactive orotic acid after the administration of estrogen. tRNA Ser(AGU,C) and tRNASer (UCU,C,A) were extensively purified by chromatography on benzoylated DEAE-cellulose in the presence and absence of Mg2+ and their radioactivities determined. In three separate labeling experiments, the difference in radioactivity of pulse-labeled and chased tRNASer (AGU,C) vs. that of tRNASer(UCU,C,A) was approximately 2-fold, suggesting a slower rate of degradation of tRNASer(AGU,C) during vitellogenin induction. Calculation of the approximate half-lives of the two tRNASer species indicates that the half-life of tRNASer (AGU,C) was increased from 3.1 days to 6.2 days during vitellogenin induction, while that of tRNASer (UCU,C,A) was essentially unchanged (2.6 days). Regulation of tRNA degradation which is possibly connected with the frequency of its use in ribosomal protein synthesis may help to explain why, in many differentiated cells, the tRNA population is adapted to the amino acid composition of the synthesized proteins. PMID- 6914870 TI - The effects of small doses of oligopeptide elastase inhibitors on elastase induced emphysema in hamsters: a dose-response study. AB - Our previous studies have indicated that the synthetic elastase inhibitor N acetyl-L-alanyl-L-alanyl-L-prolyl-L-alanyl chloromethylketone (AAPACK) administered intraperitoneally in divided doses totaling 19 mg, prior to and after a single intratracheal injection of elastase, substantially inhibited the development of experimental emphysema. The present studies evaluated the effects of 1.1, 4.1 and 8.0 mg AAPACK administered in divided doses 10 min prior to and 10, 30, and 50 min after a single intratracheal dose of elastase. The development of emphysema was essentially eliminated by 4.1 and 8.0 mg of AAPACK and markedly diminished with 1.1 mg AAPACK. The AAPACK was excreted rapidly in the urine at 30 to 60 min after its administration. Elastase inhibitory capacity (EIC) in urine was elevated to 14 times that in serum at the corresponding collection times. The plasma elastase inhibitory capacity was only slightly increased after administration of AAPACK and was not a sensitive indicator of elastase inhibition in the plasma. PMID- 6914871 TI - You can't generalize about competency from nursing degrees. PMID- 6914872 TI - Quality control circles solving OR problems. PMID- 6914873 TI - Winning through communication. PMID- 6914874 TI - From RN to BSN: pursuing the degree. PMID- 6914875 TI - Rigid endoscopy of the respiratory tract. PMID- 6914876 TI - Scope set check lists end delays, complaints. PMID- 6914877 TI - Transfusion mortality; with special reference to surgical and intensive care facilities. PMID- 6914878 TI - Membership survey provides guidance in planning services. PMID- 6914879 TI - Viewpoint: provider licensing--a monopoly won't work. PMID- 6914880 TI - Nursing evaluation in rehabilitation. PMID- 6914881 TI - Autonomic dysreflexia: a nursing challenge. PMID- 6914882 TI - Myelomeningocele: a review and update. PMID- 6914883 TI - Physical fitness as a facilitating factor in nursing. PMID- 6914884 TI - Nurses, money and independent practice. PMID- 6914885 TI - Love as prosperity power. PMID- 6914888 TI - Aboriginal Community College. PMID- 6914887 TI - Improving Aboriginal health? PMID- 6914886 TI - The resistance to antimicrobial agents of Staphylococcus aureus isolated from the bovine udder. AB - Isolates of Staphylococcus aureus (total 1657) from bovine mastitis were collected from 13 laboratories throughout Australia from 1974 to 1979. They were tested for resistance to antimicrobial agents using an agar dilution method. Resistance shown was mainly to penicillin and streptomycin. Occasional strains were resistant to neomycin, lincomycin, erythromycin, tetracycline, chloramphenicol and furazolidone but multiple resistance was rare. No strain showed resistance to methicillin. Resistance to penicillin declined from 35% in 1974-75 to 7.1% in 1979. Most strains (1395) were retested to allow induction of penicillinase; 62% produced the enzyme. PMID- 6914889 TI - Change of lifestyle. PMID- 6914890 TI - Aboriginal task force. PMID- 6914892 TI - Jandruwanta rock carvings. PMID- 6914891 TI - SA's Aboriginal health initiatives. PMID- 6914893 TI - Aboriginal health--despair or progress. PMID- 6914894 TI - Pitjantjatjara Homelands Health Service. PMID- 6914895 TI - Australian Aboriginal customary laws: progress report (in part). PMID- 6914896 TI - Marching to a different drum. PMID- 6914897 TI - Aboriginal land rights and health. PMID- 6914898 TI - Regaining Aboriginality. PMID- 6914899 TI - Elastase-type activity associated with high density lipoproteins in human serum. PMID- 6914900 TI - [Susceptibility of Staphylococcus aureus to penicillin, dicloxacillin, gentamycin, erythromycin, and rifampicin]. AB - Sensitivity tests to different antimicrobial agents were performed in 290 strains of S. aureus isolated from healthy population and from patients with various infectious diseases. Resistance to penicillin G varied from 80 to 97% and beta lactamase production was demonstrated in all strains with CMI greater than 1 microgram/ml. Resistance to other drugs was variable: gentamicin 29.4%, erythromycin 24.5% and rifampicin 12%. All strains were sensitive to isoxazolyl penicillins with CMI less than 1 microgram/ml. There was no difference in the sensitivity pattern to antibiotics between strains isolated from community or from hospital acquired infections with reference to the antimicrobial resistance pattern. PMID- 6914901 TI - [Effect of serotonin on secretory and lysosomal enzyme activity in pancreatic tissue and the inhibitory properties of serum]. AB - Experiments on rats have demonstrated that changes in the serotonin level in the body intensifies pancreatic function. The pancreas shows the increased contents of trypsinogen and proelastase and those of lysosomal enzymes (cathepsins and acid phosphatase). Administration of serotonin leads to the reduction of the inhibitory properties of blood serum versus proteolytic pancreatic enzymes. Administration of serotonin to animals with the preliminarily ligated pancreatic duct results in the development of pancreatitis with a pronounced fat necrosis of the pancreatic tissue. PMID- 6914902 TI - Properties of sulfatides in factor-XII-dependent contact activation. AB - Incubation of normal human plasma with low amounts of sulfatides resulted in the initiation of intrinsic coagulation and the appearance of kallikrein activity. The optimal initiation of procoagulant and kallikrein amidolytic activity was dependent on the presence of factor XII, high molecular weight kininogen, and prekallikrein. Since the activated partial thromboplastin clotting times in prekallikrein-deficient plasma approach normal values upon prolonged incubation with kaolin, this phenomenon of autocorrection was studied and found to be even more pronounced in the presence of sulfatides. Autocorrection was essentially completed in 5 min in the presence of sulfatides, whereas a preincubation of 15 20 min was required in the presence of kaolin. The limited proteolysis of 125I factor XII in plasma during incubation with activating material or during clotting was determined. Cleavage of factor XII was more rapid and more extensive in the presence of sulfatides than in the presence of kaolin. In prekallikrein deficient plasma, factor XII cleavage was completed within 5 min in the presence of sulfatides and within 15 min in the presence of kaolin. Thus, the appearance of factor-XII-dependent coagulant activity correlates with the limited proteolysis of factor XII when normal or prekallikrein-deficient plasma is activated by sulfatides or kaolin. PMID- 6914904 TI - Childhood M.S. PMID- 6914903 TI - Continuous ambulatory peritoneal dialysis: treatment of choice for some children. PMID- 6914905 TI - Issues in rural health care planning. PMID- 6914906 TI - Helping children and their families grieve. PMID- 6914907 TI - Bureau of Human Prescription Drugs, Health Protection Branch issues guidelines for safe handling of cytotoxic agents. PMID- 6914908 TI - You and the law: negligence in the hospital labor room: a tragic lesson for all concerned. PMID- 6914909 TI - [Planning of services for the mentally retarded patient - a process approach]. PMID- 6914910 TI - Community nursing care for the mentally retarded. PMID- 6914911 TI - [The mentally retardation child and the community health nurse]. PMID- 6914912 TI - Preparing the nurse to render a service to the mentally retarded. PMID- 6914913 TI - The implementation of the case assignment method of patient care at the Dr. A.J. Stals Care and Rehabilitation Centre. PMID- 6914914 TI - [The mentally retarded child and the nurse in genetic services]. PMID- 6914915 TI - Social work in mental retardation. PMID- 6914916 TI - Policy on the care of the mentally retarded. PMID- 6914917 TI - [Audio therapy with the mentally retarded]. PMID- 6914918 TI - Who is the right person to look after the mentally retarded? PMID- 6914919 TI - [Aspects of tertiary education - methods and media. Choice and introduction of teaching materials in a lecture]. PMID- 6914920 TI - [Aspects of tertiary education - evaluation. Evaluation of students]. PMID- 6914921 TI - [Aspects of tertiary education - evaluation. Evaluation of instructors' teaching]. PMID- 6914922 TI - School performance and stability of student nurses. PMID- 6914923 TI - Anaemia: a practical approach for nursing and paramedical specialties. PMID- 6914925 TI - [Care of our patients from a psychological viewpoint - facts or myths]. PMID- 6914924 TI - Understanding and handling mental disorders in the aged. PMID- 6914926 TI - [Aspects of tertiary education - methods and media. The lecture]. PMID- 6914927 TI - [Aspects of tertiary education - methods and media. Small group instruction]. PMID- 6914928 TI - [Aspects of tertiary education - methods and media. Practice and field work]. PMID- 6914929 TI - [The dying child in the hospital]. PMID- 6914932 TI - The dynamics of the nursing process. PMID- 6914933 TI - Illness behaviour of some White South Africans. PMID- 6914931 TI - [Cystic fibrosis]. PMID- 6914930 TI - Development of maternal and child health services in the minority communities of Israel. PMID- 6914934 TI - [A study of parameters of prognostic significance in the head-injured patient]. PMID- 6914935 TI - Nursing continuing education in the United States. A paper delivered at the Symposium "Total Health is Born in Midwifery", Johannesburg, March 1981. PMID- 6914936 TI - Neonatal intensive care. Paper presented at the Symposium "Total Health is Born in Midwifery", Johannesburg, 11 - 13 March 1981. PMID- 6914937 TI - Preparing for the last fling. Paper presented at the Symposium, Preparing for the Last Fling, Sandton, February 1981. PMID- 6914939 TI - Antibiotic therapy in neurosurgical infections. PMID- 6914938 TI - [Creation of a therapeutic environment for the child in a hemodialysis unit. Report delivered at the 6th Annual Congress of the Kidney Care Society of South Africa, February 1981]. PMID- 6914940 TI - Exaggerated fractional sodium excretion in hypertension with advanced renal disease: the role of renal prostaglandin and kallikrein. AB - 1. The role of renal prostaglandin E (PGE) and kallikrein in the mechanism of the exaggerated fractional sodium excretion in hypertensive patients with advanced renal disease was investigated. 2. Urinary excretion of PGE and kallikrein was significantly decreased in patients with sustained hypertension. 3. Four times higher values for fractional sodium excretion and four or five times higher values for the urinary excretion of PGE corrected for creatinine clearance were found in patients with sustained hypertension. There was a significant positive correlation (r = 0.677) between the two, suggesting that PGE in the renal tubular compartment may be involved in the mechanism of the exaggerated fractional Na excretion in patients with advanced renal disease. 4. The urinary excretion rate of kallikrein corrected for creatinine clearance was three times greater in patients with borderline hypertension, but not significantly increased in those with sustained hypertension, compared with that in healthy volunteers. PMID- 6914941 TI - Cancer chemotherapy: a review. PMID- 6914944 TI - Surgical treatment of morbid obesity. PMID- 6914942 TI - Collection and handling of specimens. PMID- 6914945 TI - 5-Hydroxytryptamine uptake by lungs of hamsters with pulmonary emphysema. AB - Elastase-induced emphysema in hamsters was used as a model to determine whether this type of chronic lung injury affected the metabolic function of pulmonary endothelium. 5-Hydroxytryptamine (5-HT) uptake was studied in isolated perfused lungs of hamsters from a control group and from those with emphysema of various severity. After measuring 5-HT uptake, we determined the mean linear intercept and internal surface area for each lung. The concentration of 5-HT used in the perfusate ranged from the level in the resting hamster to supraphysiologic levels. The results reveal that elastase-induced emphysema does not affect 5-HT uptake by the isolated perfused hamster lung despite significant loss of alveolar surface area. PMID- 6914943 TI - Emergency care update! Disaster! Prepare for the possibility. PMID- 6914946 TI - [Alcoholic cardiomyopathy]. PMID- 6914947 TI - [Migraine]. PMID- 6914948 TI - [Paroxysmal disturbances of heart rhythm]. PMID- 6914949 TI - [Congenital pseudarthroses of the leg bones]. PMID- 6914950 TI - [Electrocardiographic study method]. PMID- 6914952 TI - [Acute abdomen]. PMID- 6914951 TI - [Organization and instruction of the population in patient care at home]. PMID- 6914953 TI - [Closed craniocerebral injuries]. PMID- 6914955 TI - [Health education movies to propagandize a healthy mode of life]. PMID- 6914954 TI - [Propaganda for physical culture]. PMID- 6914956 TI - [Competition for the title of "Best in the Profession"]. PMID- 6914957 TI - [Chronic cholecystitis. Chronic pancreatitis. Mechanical jaundice]. PMID- 6914958 TI - [Cervical pregnancy]. PMID- 6914959 TI - [Enterobiasis]. PMID- 6914960 TI - [Infectious mononucleosis in adolescents]. PMID- 6914961 TI - [Injury to the knee joint menisci]. PMID- 6914962 TI - [Therapeutic care for burn patients at a feldsher center]. PMID- 6914963 TI - [Medical personnel of the Federal Republic of Nigeria]. PMID- 6914964 TI - [Organization of obstetrical and gynecological care for women working in industrial enterprises]. PMID- 6914965 TI - [Adrenogenital syndrome and pregnancy]. PMID- 6914966 TI - [Acute dysentery]. PMID- 6914968 TI - [Errors and difficulties connected with duodenal intubation]. PMID- 6914969 TI - [Recognition of the main electrocardiographic syndromes]. PMID- 6914967 TI - [Use of bee venom in medicine]. PMID- 6914970 TI - [Structure and activities of the nursing service in health care facilities]. PMID- 6914971 TI - [Role of the nurse in the organization of services offered in a child care center]. PMID- 6914972 TI - [The concept integral nursing care from the viewpoint of the relationship patient nurse]. PMID- 6914974 TI - [Objective of clinical instruction in nursing education]. PMID- 6914973 TI - [Current aspects of thalassemia]. PMID- 6914975 TI - [Primary health care in Belgium: building a better world]. PMID- 6914977 TI - [Formation of metastases in the ovaries in operated squamous cell carcinoma of the cervix uteri (author's transl)]. AB - Formation of metastases in the ovaries in carcinoma of the uterine cervix is a rare occurrence. 749 ovaries were subjected to histological examination in 980 operated patients with squamous cell carcinoma of the cervix. A metastatic carcinoma in the ovary was identified in four patients (0.5%). In three patients, a tumour had formed simultaneously in the corpus uteri. This might point to a metastatic spread of the tumour in the same manner as in carcinoma of the endometrium. In view of the low incidence of metastases in the ovaries adnexectomy would not be generally justified. PMID- 6914976 TI - [Cytological differential diagnostic accuracy in severe dysplasia and carcinoma in situ of the cervix and possible clinical consequences (author's transl)]. AB - Since 1943 when Papanicolaou introduced cytology into gynecology the method has changed from a simple screening test into a sophisticated morphologic technique, the differential cytology. In Germany this development is documented by an improved cytologic classification (Munchner Nomenklatur). An own material is presented consisting of 520 cases of histologically proven severe dysplasias and in situ carcinomas. It can be shown that careful and critical use of differential cytology with due regard to its limits can improve the accuracy of the cytologic prediction of a cervical lesion. A delineation against invasive cancer is possible with a hundred percent accuracy. On the basis of these results it seems justifiable to perform a primary hysterectomy without pretherapeutic cone-biopsy. It is pointed out that this procedure is only possible in institutions were the possibilities of differential cytology are well-known and--which is more important--where the limits of the method are known and respected. In any case of doubt the procedure of diagnosis and therapy has to be discussed and planned in close cooperation between the clinicians and the morphologists. PMID- 6914978 TI - [Morphological and clinical aspects of the so-called sinus tumours of the ovary (author's transl)]. AB - Data from literature as well as our own studies are used in the discussion of differential diagnosis of the so-called endodermal sinus tumours. Clinical and paraclinical aspects of this once lethal tumour species are reported. New therapeutic strategies are presented consisting of the introduction of new, effective combinations with adjuvant chemotherapy. Thus at early stages a conservative surgical approach seems to allow the preservation of fertility in these generally young women. But even in more advanced cases the administration of a modern adjuvant polychemotherapy is likely to result in higher survival rates. PMID- 6914979 TI - [Clinical anatomic and urodynamic investigations in stress-incontinence women (author's transl)]. AB - In 398 patients suffering from urinary incontinence seven urodynamic parameters were investigated. 75% resp. 78% had a normal max. urethral closure pressure. Only a part of the women was characterized by a descensus of the genital tract. Some more patients showed anatomic abnormalities in the urethrovesical configuration by x-ray urethrocystogram. 1/5 res. 1/3 of descendent anterior vaginal walls proved to have a cystocele. If one requires for successful incontinence operation a normal max. urethral closure pressure and an objectively proven abnormality of the urethrovesical configuration, only 65% resp. 67% of our incontinence women have a chance of being cured by incontinence operation. PMID- 6914980 TI - [Comparison of preoperative and postoperative findings after stress incontinence surgery in women (author's transl)]. AB - The authors attempt to assess success of surgery in 44 women with stress incontinence treated with colporrhaphia ant. et post. with/without vaginal hysterectomy, by evaluating preoperative and postoperative findings. Examination comprised, after detailed anamnesis, besides general gynaecological examination and examination of urine for pathological constituents, the following methods: simultaneous urethrocystometry, cystometry, urethrocystography, electromyography of the sphincter system, as well as uroflowmetry. It was found that despite subjectively reported success of operation there was often no direct correlation to the actual, objective findings. This underlines once again that assessment of the result of surgery is possible only via application of a wide range of diagnostic procedures postoperatively with the same methods. The results obtained are discussed with reference to reports published in medical literature. PMID- 6914981 TI - [On uterine and adnexal inflammatory complications with intrauterine devices (author's transl)]. PMID- 6914982 TI - [Endometriosis--implantation or metaplasie? (author's transl)]. AB - The article deals with the various theories, hypotheses, localisations and experiments in connection with the genesis of uterine and extrauterine endometriosis. It is explained that there is not just one single valid cause; rather, it will be necessary to resort to various theories, depending on the localisation of the endometrial heterotopia. The article describes the case of a young woman with genital malformation combined with ovarial endometriosis. This malformation syndrome is known as Mayer-Rokitansky-Kuster syndrome with congenital aplasia of the vagina and a rudimentary uterus bicornis solidus. Since such uteri do not contain any endometrium which is capable of functioning, this would exclude any canalicular, haematogenic, lymphogenic, embolic, metastatic or homotransplantational cause of endometriosis. In fact, ovarial endometrial tissue heterotopia is due to pluropotentiality of the coelomic epithelium and is produced by indentation of cortical epithelium and segmentation. PMID- 6914983 TI - [Treatment of dry labour in rupture of membranes by conservative approach (inhibition of uterine contraction) with fenoterol (author's transl)]. PMID- 6914984 TI - [Experiences in the assessment of the subpartal cardiotocogram (author's transl)]. AB - 750 cardiotocographic curves of the last 30 minutes prior to vaginal delivery were assessed retrospectively according to the CTG score after Hammacher et al. (6). The aim of this study was to examine the prognostic value of the CTG score with regard to the foetal acid-base stains. The results obtained showed a distinct interdependence between the CTG score and the risk of foetal acidosis. Correct interpretation of the CTG can be ensured only if all three different CTG parameters are considered. The most frequent and reliable pointers to the existence of foetal acidosis are the occurrence of severe variable or late decelerations which can be detected from an examination of the floating-line pattern. PMID- 6914986 TI - [Will pregnancy not immediately recognized during preventive screening for cancer and followed by childbirth involve legal liability of the physician? (author's transl)]. PMID- 6914985 TI - [Practical-clinical aspects in primary clearing of the upper respiratory tract in newborn (author's transl)]. AB - There are contradictory descriptions in the literature about the methods as well as the sequence of clearing the upper respiratory tract of new-born babies. In order to clarify this problem anatomical, physiological and pathophysiological aspects of the fetal and neonatal respiratory system are described. Intrauterine asphyxia can lead to aspiration of amniotic fluid (containing meconium, squamous epithelium, lanugo hair). During delivery the fetal airway is cleared by compression of the thorax. Through suction of the mouth, throat and nose--in exactly this defined sequence--before birth of the thorax, aspiration of potentially damaging material can be prevented. The particular problem associated with meconium-steined amniotic fluid is described. PMID- 6914988 TI - [The mortality from thrombo-embolism following gynaecological operations without anti-coagulation treatment (author's transl)]. PMID- 6914989 TI - [Urinary bladder complications following Wertheim operations--recommendations for a controlled follow-up with comparable conditions (author's transl)]. AB - At defined times prior and following a Wertheim operation for cancer of the uterine cervix the patients were investigated for the functional parameters of the lower urinary tract. The residual urine was determined. Stress incontinence and urgency incontinence were measured with urethrocystometry. The sensitivity and the micturition were evaluated from subjective data. The results of 237 investigations in 192 operated women are described and compared to previous papers on the subject. Stress incontinence increased to double the pre-operative incidence following the Wertheim operation. An urgency incontinence was quite rare. A lack of feeling of fullness to the bladder as a sign of disturbed bladder sensitivity was present 5 months post-operatively in 6 of 45 patients (13%). This was present in only 1 of 119 patients (1%) after five years. 1/3 of the women had difficulty with spontaneous micturition five months following the operation. 1/10 of the women had difficulty with spontaneous micturition 5 years after the operation. There was no residual urine five months after the operation in 9/10 of the patients and five years following the operation almost 100% of the patients had no residual urine. It was noted that difficulty with spontaneous micturition with residual urine and urgency incontinence did not necessarily result in concomitant bacteriuria. Suggestions are presented how future investigations with similar questions may lead to comparable results. PMID- 6914990 TI - [Ventral plasty of the levators a neglected method for the operative treatment of stress incontinence (author's transl)]. AB - A method for the operative treatment of stress incontinence in the female is described. The anatomical importance of the levator sling behind the urethra is stressed. The pubococcygeal muscles which have been lateralized by trauma are prepared. The levator ani muscle with its fascia is mobilized and the two muscle components of the perineal muscles are joined in the midline. The muscular adaptation starts behind the symphysis and is carried on dorsally as far as necessary. In this way a strong sub-urethral and subvesical muscular plate is created. In 673 patients who were treated by this method recurrence was rare. A concomitant six weeks. Urodynamic studies and physical measurements showed the pivotal importance of the levator ani muscle for the maintenance of continence. PMID- 6914987 TI - [Ultrasonic screening in pregnancy--caution against exaggerated demands]. PMID- 6914991 TI - [The operative treatment of enterocele and prolapse of the vaginal vault (author's transl)]. AB - Between 1969 and 1980 11 operations according to Williams-Richardson, 23 abdominal sacropexies according to Wagner-Kuestner and 4 operations according to Amreich-II were performed for the treatment of enteroceles and prolapse of the vaginal vault. The combination of these operative methods with colpoperineorraphies and Marshall-Marchetti-Krantz operations and lyodura ribbon operations according to Zoedler for the urethro-vesical angle is described. Continence an elevation of the vaginal fornix was obtained by the operation according to Williams-Richardson and by the fixation of the vagina to the sacrospinal ligament. With the Williams-Richardson operation 1 enterocele occurred which was corrected with the vaginal fixation to the sacro-spinal ligament. Following fixation to the promontary 2 enteroceles, 4 cystocele, and one rectocele occurred in 4 patients. Three of these had urinary incontinence. The complications are described. The vaginal fixation to the sacro-spinal ligament according to Amreich II at times combined with the lyodura sling operation of Zoedler is today the preferred operative method. PMID- 6914992 TI - [Genital injuries during the late postmenopause and senium (author's transl)]. AB - Genital injuries of 61 patients who were at least 60 years of age were treated in 17 West Berlin departments of gynaecology from 1970 to 1979. 39 cases were due to coitus. Rape was responsible in 5 cases. Various other causes were recorded in 15 women. The etiology of the laceration remained unknown in 2 cases. Sexual dysfunction due to age-related changes of the female genital tract resulting in injuries represents a specific problem of geriatric gynaecology. PMID- 6914993 TI - [Pseudocondylomata of the vulva (author's transl)]. AB - The present casuistry study deals with condylomata acuminata-like lesions of the vulva of two sexually mature 20 and 22 years old Turkish sisters, and a 34 year old Yugoslavian women. Based on clinical and histological particularities the verruciform structures are interpreted as - atavistic? - malformation without functional significance. Their relation to the papillas of corona glans are proved in detail. PMID- 6914994 TI - [Report of 22 cases of congenital adrenal genital syndrome (AGS) observed in the reproductive age group (author's transl)]. AB - 22 adolescent and adult female patients - 15 to 37 years old - with the Congenital Adrenogenital Syndrome (AGS) were examined. In only 7 cases the disease was diagnosed immediately after birth. Among 16 patients, which had already undergone a reconstructive operation of the external genitalia, only 5 were satisfied with its cosmetic and functional results. 11 women could not do a sexual intercourse due to the malformed external genitalia. Menarche occurred spontaneously in only 10 cases under cortisone-therapy. At the time of investigation only 4 patients had regular menstrual-cycles. Adolescents suffering from AGS should be referred to a pediatric-gynecologist not later than puberty to assure an individual guidance relating to menstruation, surgical intervention, sexual-life and fertility. PMID- 6914995 TI - [Habitual abortion: diagnostics and therapy in gynaecological practice (author's transl)]. AB - According to several literature surveys women with three consecutive and clinically ascertained spontaneous abortions appear to have without treatment an abortion risk of 50 to 60 per cent in the course of any further pregnancy. For improving prognostication various conditions leading to habitual abortions have to be clarified before the onset of a new pregnancy. Among our patients corpus luteum dysfunctions (35 per cent) and anomalies of the uterus (17 per cent) showed the highest frequency. Our patients also had an increased frequency of pathological spermiograms. Their influence on the incidence of habitual abortions remains, however, unclear. Infectious diseases and metabolic disorders (5 per cent) as well as chromosomal aberrations (6 per cent) appeared to be less frequent. Controversial views on the consequences of blood group incompatibilities of the spouses continue to exist. Conflict-oriented personalities of patients seem to play a major role. After evaluating the findings in literature pertaining to habitual abortions and on the basis of our own results (110 patients) diagnostic and therapeutic guidelines have been worked out. By employment of the individually required therapy 90 per cent of the patients with habitual abortions were able to successfully complete a further pregnancy. PMID- 6914997 TI - [Prevention of thromboemolism in gynecologic surgery]. PMID- 6914996 TI - [Pyrexia during delivery (author's transl)]. AB - Amnionitis with pyrexia during labor and delivery and the perinatal complications of this syndrome are described. In our series the incidence of pyrexia during delivery was 0.54%. In 70 of 83 cases (84%) an intra-uterine infection was assumed to be the cause of the pyrexia. In 13 of 83 cases (16%) an extra-genital infection was the presumed cause. Intra-uterine infections are a grave danger for the mother and the newborn and constitute a severe complication. The mortality in cases with pyrexia during labor and delivery was elevated to 7 of 83 newborns (9%). Rapid delivery and the timely administration of antibiotics in sufficiently high dosages can prevent the manifestations of severe infections. Recommendations for the obstetric management of cases with pyrexia during labor and delivery are given. PMID- 6915000 TI - Pioneer spirit. PMID- 6915001 TI - Center of Healing Light: a community center. PMID- 6914999 TI - Genetic variants of properdin factor B (Bf) in Papio hamadryas baboons. PMID- 6914998 TI - [Kallikrein-kinin system indices in neurocirculatory dystonia patients who work in synthetic rubber manufacture]. PMID- 6915002 TI - Relative efficacy of neomycin and ampicillin against urease producing organisms. PMID- 6915003 TI - [Observation of neurological symptoms]. PMID- 6915006 TI - [The studio "a votre sante"; model of first-line health care in a rural community]. PMID- 6915004 TI - [Adult patient-education in the emergency room...is it feasible?]. PMID- 6915005 TI - [The socio-affective maladapted adolescent]. PMID- 6915007 TI - [Better understanding the aging of man]. PMID- 6915008 TI - [Educational program for diabetics]. PMID- 6915009 TI - The "hospital epidemiologist" in U.S. hospitals, 1976-1977: a description of the head of the infection surveillance and control program. Report from the SENIC project. AB - As part of the first two phases of the SENIC Project (Study on the Efficacy of Nosocomial Infection Control), information was collected from the heads of the infection surveillance and control programs (ISCPs) in U.S. hospitals. The data were analyzed to describe these respondents and to determine whether differences among them were related to their areas of professional training or to characteristics of the hospitals where they were located. The findings indicate that the ISCP heads constitute a very heterogeneous group, with substantial differences in age, professional training (40% are pathologists), characteristics of their medical practices, memberships in professional organizations related to infection control, time spent in ISCP activities, approach to epidemiologic problems, and opinions on the preventability of nosocomial infections and the seriousness of infection problems in their hospitals. These differences are related strongly to the ISCP heads' professional training, size of hospital, and, to a lesser extent, medical school affiliation, but there is little evidence that the differences are related to regional or urban-rural location or type of ownership of the hospitals. The average ISCP head estimates that about half of all nosocomial infections are preventable, but these estimates vary inversely with tenure in the position and the tendency to approach a clinical problem epidemiologically. PMID- 6915011 TI - Infection control committee records. PMID- 6915012 TI - Designing hospital infection studies. AB - The design of investigations of hospital infections often will make a difference between results that are useful and results that only appear to be. The importance of study design and dimensions cannot be overemphasized. Much has been written about methods of research. Most universities and many large hospitals have persons trained in research design and analysis. The more that investigators of nosocomial infections talk with and collaborate with persons who have such training, the more accurate and more productive their research is likely to be. PMID- 6915013 TI - Staphylococcal infection in hospital roommates. PMID- 6915010 TI - A pseudoepidemic of pulmonary fungal infections related to fiberoptic bronchoscopy. AB - During a three-week period a pseudoepidemic of fungal infections occurred involving patients from two different services. Trichosporon cutaneum and a Penicillium species were isolated from bronchial washings and sputa obtained after fiberoptic bronchoscopy on eight clinically uninfected patients. Investigation revealed contamination of cocaine solutions used for topical anesthesia during bronchoscopy. Contamination is thought to have occurred during preparation of the solutions by pharmacy personnel. Revision of techniques used in formulating and dispensing the solutions resulted in cessation of the pseudoepidemic. PMID- 6915014 TI - Decision-making and probability. PMID- 6915015 TI - Isolation techniques for hospital patients with viral hepatitis: new guidelines premature. PMID- 6915016 TI - Methicillin-resistant Staphylococcus aureus: interstate spread of nosocomial infections with emergence of gentamicin-methicillin resistant strains. AB - A methicillin-resistant strain of Staphylococcus aureus (MRSA, phage type 84/85) was introduced into City of Memphis Hospital by a burn patient who had recently been treated for MRSA bacteremia in another institution 500 miles distant. Despite prompt recognition of the problem and institution of isolation procedures, six other patients developed secondary colonization during the ensuing six months, and five of these experienced clinically significant infections with MRSA. Three of the patients originally infected with MRSA, as well as two additional patients, subsequently developed colonization with staphylococcal strains of phage type 84/85 that were resistant to both methicillin and gentamicin (MRGRSA). Spread of the staphylococcal strains was most likely accomplished primarily via passive transfer from person to person. The hydrotherapy unit, which became contaminated with both MRSA and MRGRSA, may have played a secondary role. As illustrated by this outbreak, patients carrying potentially dangerous bacterial strains should be identified and informed of the problems posed by such carriage. It may be imprudent to admit such patients to hospitals that are free of the potential pathogen. The outbreak described here exemplifies a number of potential problems associated with control of nosocomial staphylococcal infections: (a) interhospital spread of methicillin-resistant strains; (b) secondary patient-to-patient intrahospital spread; and (c) emergence of even more resistant strains, possibly associated with selective pressures exerted by widespread use of broad-spectrum antimicrobial agents. PMID- 6915017 TI - Dilemmas of the beta-lactam explosion. PMID- 6915019 TI - The use of microbiology principles in infection control. PMID- 6915018 TI - Observations relating to an inter-hospital outbreak of methicillin-resistant Staphylococcus aureus: role of antimicrobial therapy in infection control. AB - Clinical, bacteriologic, epidemiologic and hospital infection-control observations related to an inter-hospital outbreak of methicillin-resistant Staphylococcus aureus are described. The outbreak involved 66 patients at the University of Oregon Health Sciences Center (UOHSC) and its closely affiliated VA hospital, the Portland VA Medical Center (PVAMC). No environmental source of infection was identified; person-to-person transmission was most likely responsible for its spread. Surveillance cultures demonstrated nasal colonization in house staff and nursing personnel at both hospitals. Inter-hospital transfer of infection was, in all likelihood, achieved via nasal carriage by a single physician. Case-control analysis indicated a significantly increased risk (p less than 0.05) of acquisition of infection related to age, number of days hospitalized, severity of underlying disease and number of invasive procedures. Prior antibiotic receipt was a significant risk factor when analyzed by univariate analysis (p less than 0.01), but, in contrast to previous studies, this was not a significant risk factor (p greater than 0.05) when related variables were controlled by multivariate analysis. Prevention of spread of infection by routine infection control measures was less effective at PVAMC than at UOHSC. Patients at PVAMC were significantly older and had longer durations of hospitalization (p less than 0.05). Antimicrobial therapy of colonized patients and personnel appeared to assist in the control of the outbreak at PVAMC. Antimicrobial therapy with topical bacitracin and oral rifampin, alone or in combination with oral trimethoprim-sulfamethoxazole, was effective in eliminating colonization with methicillin-resistant S. aureus. PMID- 6915020 TI - Dealing with confounding factors. PMID- 6915021 TI - The relationship of nursing to primary health care internationally. PMID- 6915023 TI - State legislature must act before April '82 to save Board. PMID- 6915024 TI - The New Hampshire story - behind the scenes. PMID- 6915025 TI - Fetal alcohol syndrome--the incurable hangover. PMID- 6915026 TI - Diabetes and the role of the health visitor. PMID- 6915027 TI - The Charles Lea Center for Rehabilitation and Special Education Inc. PMID- 6915029 TI - Enuresis: present trends in treatment. PMID- 6915030 TI - A crying baby advisory service. PMID- 6915028 TI - Letter from Thailand. PMID- 6915031 TI - Health visiting the elderly in the 1980s-- do we care enough? PMID- 6915022 TI - Measles vaccination coverage in rural areas: a study of seven villages in Cameroon. PMID- 6915032 TI - Know your organizations: the work of ACCEPT - Alcoholism Community Centers for Education, Prevention and Treatment. PMID- 6915034 TI - The hospitalized child and the need for mastery. PMID- 6915033 TI - Emotional support for the breast-feeding mother. PMID- 6915036 TI - Preventive dentistry for the pediatric patient. PMID- 6915035 TI - Sudden infant death syndrome and infant apnea: current questions, clinical management, and research directions. PMID- 6915038 TI - A collaborative continuing education model. PMID- 6915037 TI - Three-day and one-day chemotherapy for urinary tract infections in general practice. PMID- 6915040 TI - From academia to practice--realities of delivering nursing education in a medical center. PMID- 6915039 TI - Evaluation for change. PMID- 6915041 TI - Establishing a Nursing Journal Club for professional education and certification. PMID- 6915042 TI - The views of Illinois nurses toward requiring continuing education for relicensure. PMID- 6915043 TI - Methods of teaching--revisited open forum; buzz sessions. PMID- 6915044 TI - Notes on continuing education: policies of the staff development department. PMID- 6915045 TI - Legal aspects of the expanded role: informed consent. PMID- 6915047 TI - Breast feeding: success or failure. AB - Awareness of the important role of breast feeding in child health and the reproductive cycle, which is well documented elsewhere, necessitates an examination of the changing practice of breast feeding. This paper reviews these changing practices both in Western and developing societies, examines the problems which lead to lactation failure, and looks at factors related to success in breast feeding. In the light of the need for practical help for successful breast feeding. the present system of support both in hospital and at home is then discussed. An alternative system of structured home support for post-natal women, which has been shown to increase the success rate of breast feeding, is outlined. The way in which this system acts is discussed and the implications for both mothers and health staff are considered. PMID- 6915046 TI - The social construction of illness experience: families with a chronically-ill child. AB - This paper examines how parents constructed the illness of a child with chronic sickness. The focus is on eliciting the parents' explanatory model of illness, that is, how they understood and described their child's illness, and how they managed their interactions with the child. The data were collected by using an ethnographic approach. In addition to obtaining parents' accounts, naturally occurring interactions between parents and children were observed and tape recorded. The paper discusses the parents' semantic definition of the "child as normal'. In actual practice, however, the child's life was regulated by the parents' understanding of the biomedical model, and included time schedules dictated by the sickness and seclusion from other children. Adjustment in family lifestyle was seen as necessary to accommodate the child's health problem. It is argued that the parents' interactions with the child contain the essential feature of paradoxical communication. An ethnographically based theoretical model of the social construction of sickness careers is introduced. The paper gives verbatim accounts of naturally occurring interactions so that the reader has access to the data upon which the author's interpretations are based. The implications for nursing practice are discussed. PMID- 6915048 TI - Eye opening of the newborn at and up to 20 minutes after birth. AB - Early eye contact between mother and baby is considered important in the attachment process between mother and baby. How soon after birth is it possible for eye contact to occur? How soon after birth will a baby open his eyes spontaneously?- Where is the baby physically at that time? Is hospital labour ward routine conducive to early eye-to-eye contact between mother and baby? Discussing these questions with midwifery colleagues, it became apparent that we were unable to answer with any degree of certainty, the question "How soon after birth will a baby open his eyes spontaneously?' It was felt that "most babies open their eyes at or very soon after birth'. How soon was "very soon'? and did all babies open their eyes soon after birth? Were there any observable influencing factors? Is so, what were they? In this study of 104 babies, 30 babies opened their eyes at birth, and the remainder, except three, opened their eyes ranging from within 1 minute of birth to within 20 minutes of birth (20 minutes being the time limit set for the study). Some babies were observed to open their eyes momentarily only the very first time, keeping their eyes open longer subsequently. PMID- 6915049 TI - Bereavement and the elderly: a critical review with implications for nursing practice and research. AB - Loss is a common occurrence in the lives of the elderly. One of the most profound losses is the death of a spouse. Yet, infrequent and predictable as this event is for older adults, we know very little about the grieving process or the resolution of grief among this age group. For nurses who care for older clients an understanding of loss and bereavement is important in order to provide appropriate and timely support. In this paper the nature of grief and bereavement behaviour is discussed beginning with the earliest empirical work done in 1930 and including a synopsis of six major variations of grief. A comprehensive review and critique of current investigations provides the basis for suggesting that, because of flaws in conceptualization and design, there are substantial limits on the relevance of existing knowledge of grief for an understanding of this phenomenon among the aged bereaved. A beginning theoretical integration and discussion of key concepts related to bereavement and the elderly is provided. This discussion is summarized in a proposed model. This paper concludes with suggestions for nursing research and practice. PMID- 6915050 TI - An investigation into the validity of specifying 5 "O' levels in the General Certificate of Education as an entry requirement for the education and training of district nurses. AB - District nursing, like many other professionalizing occupations, has stipulated that possession of five ordinary level GCE passes might constitute one criterion of entry. This paper reports a longitudinal study over four intakes of district nurse students in one teaching centre and examines the relationship between selection criteria, in particular educational achievement prior to entry to the course, and the students' achievement during this. The research explored the relationship between educational achievement prior to commencing their course of study and the level of academic and practical performance during it. Additionally other factors, including the results of aptitude and personality tests, were examined to see if they would provide indication of the level of the students; grades during training. No factors were discovered that might provide an adequate basis for selection, which raises questions about trying to specify any pre requisite for selection other than state registration and appropriate professional experience until further research has been undertaken. PMID- 6915051 TI - An evaluation of a workshop for teachers of nursing by comparing the members' expectations with their opinions of the outcome. AB - Fifty-seven teachers of nursing, who comprised 42 women and 15 men and who also comprised 12 senior tutors, 16 nurse tutors and 29 clinical teachers, participated in a study to evaluate a workshop which they attended. The method of inquiry used was that of a survey by questionnaire. Two questionnaires were used, one being set at the beginning of the workshop and the other at the end of the proceedings. The learning objectives for the workshop were used as the questionnaire items and comprised 20 in all. When the before and after scores relating to the questionnaire items were compared through the use of t tests significant differences were found on 12 out of the 20 objectives. In the course of the paper the differences found are identified and discussed. Some of the limitations of the method of inquiry used are discussed and finally some conclusions are reached. PMID- 6915052 TI - Research and the standards of nursing care: what is the relationship? AB - Research and standards of nursing care are looked at to see in what way they are inter-related. The label "standards of care' is said to embrace several meanings: the quality of care and the measures against which the care can be judged. For research, it is argued, concepts must be clearly defined before they can be the subject of serious study. It is thus essential that the different meanings implied by standards are separated out. After discussion on this point, whereby the different components are analysed, quality of care, standards of care and effectiveness of care are illustrated through their inter-relationship. It is then suggested that the contribution of research to standards used as measures against which care can be judged may be either to indicate which criteria could comprise useful measures, or to indicate the limitations and constraints of the measures chosen for use. PMID- 6915053 TI - Towards professional autonomy: a commentary on "Expectations and disappointments' in development of the Royal College of Nursing. AB - The Royal College of Nursing of the United Kingdom has been engaged over recent years in a unique process of organizational change. Since 1973 sustained efforts have been made to mobilise widespread membership participation in shaping a new college structure which enables the Rcn to function effectively in representing the profession and in developing expertise on all aspects of nursing. A critical element has been creation of a network of "Rcn Centres' to provide a professional forum in each locality. A recent study by Bridget Ramsay has followed up this process. Its title, Expectations and Disappointments, reflects the mixed views of those involved on the progress which has been made. This article provides a commentary on Ramsay's analysis against the background of the complex situation of the Rcn in the early 1970s and the considerations which led the College to adopt an innovative approach to change. Particular attention is given to the influences which have made the growth of an active and integrated "Rcn at local level' quite problematic. It is suggested that the course Rcn development has taken in part reflects important elements in the nursing culture which members learn from their work in hospitals. Accordingly the Rcn experience has wider implications for the profession, not least for contemporary efforts, to achieve the greater professional autonomy necessary for nurses to implement more individualized patient care. PMID- 6915054 TI - The nursing process and standards of care: the nursing process in the United Kingdom. PMID- 6915055 TI - Special issue on the adolescent female: introduction. PMID- 6915056 TI - Adolescent fathers: adolescents first, fathers second. PMID- 6915057 TI - Sexual health needs of the mentally retarded adolescent female. PMID- 6915058 TI - Sexual assault on the adolescent female. PMID- 6915060 TI - Mainstreaming the adolescent mother. PMID- 6915059 TI - The sexual concerns of the adolescent woman with cerebral palsy. PMID- 6915061 TI - Filtrate compartmentalization. PMID- 6915062 TI - The continuous ambulatory peritoneal dialysis (CAPD) home training program. PMID- 6915064 TI - Review of nine year prevalence of hepatitis B surface antigen at the hospital of the University of Pennsylvania. PMID- 6915063 TI - Home hemodialysis training: factors affecting mastery. PMID- 6915065 TI - Patient management--pre dialysis education. PMID- 6915067 TI - Nursing care of the aged in the United States of America. PMID- 6915066 TI - Brain death--state of the art. PMID- 6915068 TI - Nursing care of the aged in Australia. PMID- 6915069 TI - Nursing care of the aged in Canada. PMID- 6915071 TI - Nursing care of the aged in Japan. PMID- 6915070 TI - Nursing care of the aged in Israel. PMID- 6915072 TI - Psychosocial issues in nursing care of the aged. PMID- 6915073 TI - Immunocytochemical localization of kallikrein in the rat exocrine pancreas. AB - The subcellular localization of kallikrein was studied in the rat pancreas using the immunocytochemical protein A-gold technique. Kallikrein was found at the level of the rough endoplasmic reticulum (RER), Golgi cisternae, condensing vacuoles, and zymogen granules of the pancreatic acinar cells as well as in the acinar lumen. The effect of various tissue processings on the immunocytochemical labeling of kallikrein was evaluated using pancreatic tissue fixed in glutaraldehyde and embedded in Epon, Lowicryl K4M, or glycol methacrylate (GMA). Compared to the results obtained with Epon, Lowicryl allowed improved resolution and specificity in the immunocytochemical labeling, while GMA retained greater amounts of kallikrein antigenicity leading to a higher intensity in the labeling; since it also gave a good ultrastructural preservation, GMA appeared to be the superior embedding medium for the localization of kallikrein. The quantitative evaluation of the labeling obtained under the three embedding conditions showed the presence of an increasing concentration gradient along the RER-Golgi-granule secretory pathway, suggesting that, like other pancreatic exocrine enzymes, kallikrein is synthesized in the RER, processed through the Golgi apparatus, and packed in the zymogen granules before being released into the acinar lumen. PMID- 6915076 TI - The role of antibiotic tolerance in the response to treatment of pyelonephritis due to Staphylococcus aureus in rats. AB - The effect of tolerance to methicillin on the response to treatment of hematogenous pyelonephritis due to Staphylococcus aureus was evaluated in rats. Tolerance was defined as a ratio of minimal bactericidal concentration to minimal inhibitory concentration of greater than or equal to 32. Rats that were infected with tolerant or nontolerant stains of S. aureus were treated with methicillin with equal success as judged by the number of bacteria in the kidneys and the proportion of rats with infected kidneys. In this animal model, tolerance does not play a role in the outcome of treatment. PMID- 6915075 TI - Mechanism of enhanced complement-dependent cytotoxicity of papain-treated lymphocytes: evidence for increased stability of classical pathway C3 convertase. AB - The mechanisms of enhanced antibody-mediated, complement-dependent cytotoxicity caused by proteolytic treatment of cells was studied in a model system based on HLA microlymphocytotoxicity methods. In this model, papain treatment of lymphocytes resulted in a) no change in antibody binding, b) a slight decrease in initial binding of C4, c) a marked increase in stability of cell-bound C4b, resulting in d) an increase of cell-bound C3, and e) no increase in lytic efficiency of the C5b-9 membrane attack complex. We conclude that the most important step in papain enhancement of lysis of lymphocytes is an increased stability of cell-bound C4b, possibly through decreased surface binding of C4-bp. This mechanism may be relevant to the pathologically increased lysis of cells occurring in patients with hereditary erythroblastic multinuclearity with a positive acidified-serum test (HEM-PAS). PMID- 6915078 TI - The nursing director's role in money management. PMID- 6915074 TI - Selective inhibition of functional sites of cell-bound C3b by hybridoma-derived antibodies. PMID- 6915077 TI - Identification of a C3bi-specific membrane complement receptor that is expressed on lymphocytes, monocytes, neutrophils, and erythrocytes. AB - Cells expressing a membrane C receptor (CR(3)) specific for C3b-inactivator- cleaved C3b (C3bi) were identified by rosette assay with C3bi-coated sheep erythrocytes (EC3bi) or C3bi-coated fluorescent microspheres (C3bi-ms). C3bi- ms, probably because of their smaller size, bound to a higher proportion of cells than did EC3bi. C3bi-ms bound to greater than 90 percent of mature neutrophils, 85 percent of monocytes, 92 percent of erythrocytes, and 12 percent of peripheral blood lymphocytes. Binding of C3bi-ms to neutrophils, monocytes, and erythrocytes was inhibited by fluid-phase C3bi, Fab anti-C3c, or Fab anti-C3d but was not inhibited by F(ab')(2) anti-CR(1) (C3b receptor) or F(ab')(2) anti-CR(2) (C3d receptor) nor by fluid-phase C3b, C3c, or C3d. This indicated that monocytes, neutrophils, and erythrocytes expressed C3bi receptors (CR(3)) that were separate and distinct from CR(1) and CR(2) and specific for a site in the C3 molecule that was only exposed subsequently to cleavage of C3b by C3b inactivator and that was either destroyed, covered, or liberated by cleavage of C3bi into C3c and C3d fragments. Lymphocytes differed from these other cell types in that they expressed CR2 in addition to CRa. Lymphocyte C3bi-ms rosettes were inhibited from 50 to 84 percent by F(ab')(2)-anti-CR(2) or fluid-phase C3d, whereas C3d-ms rosettes were inhibited completely by F(ab')(2) anti-CR(2), fluid-phase C3bi, or fluid- phase C3d. Thus, with lymphocytes, C3bi was bound to CR(3), and in addition was bound to CR(2) by way of the intact d region of the C3bi molecule. In studies of the acquisition of C receptors occurring during myeloid cell maturation, the ability to rosette with C3bi-coated particles was detected readily with immature low-density cells, whereas this ability was nearly undetectable with high density mature polymorphonuclear cells. This absence of C3bi binding to polymorphs was not due to a loss of the CR(3) but instead was due to the maturation-linked acquisition of the abiity to secrete elastase that cleaved reagent particle-bound C3bi into CR(3)-unreactive C3d. Neither neutrophils nor monocytes bound C3d-coated particles at any stage of maturation. Assay of CR(3) with mature neutrophils required inhibition of neutrophil elastase with either soybean trypsin inhibitor or anti-elastase antibodies, and the amounts of these elastase inhibitors required to allow EC3bi rosette formation increased with neutrophil maturation. Because lymphocytes bound C3bi to CR(2) as well as to CR(3), specific assay of lymphocyte CR(3) required saturation of membrane CR(2) with Fab' anti-CR(2) before assay for rosettes with C3bi-ms. Only 3.5 percent of anti-CR(2)- treated peripheral blood lymphocytes bound C3bi-ms. Therefore, among normal blood lymphocytes the majority of the 12 percent C3bi-ms binding cells expressed only CR(2) (8.5 percent), and the small proportion of C3bi-ms- binding cells that expressed CR(3) (3.5 percent) represented a distinct subset from the CR2(+) cells. Double-label assay indicated that 3.0 percent out of 3.5 percent of these CR(3)-bearing lymphocytes were B cells because they expressed membrane immunoglobulins. Of the remaining CR(3)(+) cells, 0.2 percent expressed either Leu-1 or 3A1 T cell antigens, and 0.6 percent expressed the OKM 1 monocyte-null lymphocyte determinant. PMID- 6915081 TI - Staff, patient, and cost outcomes of all-registered nurse staffing. PMID- 6915080 TI - I win--you win negotiating. AB - There are numerous other useful negotiating tools, including Escalation, the Limit, the Krunch, Call for Higher Authority, CIA, Intimidation, Churning, Phoney Offers-unfortunately, too many to detail in this short chapter. But all of these tools are based on the fundamentals of human action, reaction, and interaction. Negotiating works because it recognizes the mutual desire for satisfying needs, and it recognizes others as persons as human and fragile as ourselves. Believe this, and believe that all of us share a longing to bring greater happiness and satisfaction to our lives. Raise your goals and awareness, and conduct yourself as a skilled and ethical negotiator in your daily life. It will bring you increased satisfaction and the same time help others to achieve theirs. An "I Win You Win" philosophy will contribute to the building of a better world for all of us. PMID- 6915079 TI - Nurse burnout: what can we learn? AB - A review of the literature has uncovered some initial research on the possible causes and manifestations of burnout among nurses and other helping professionals. Essential causal factors have not yet been identified. However, burnout appears to result from the interaction of personal and structural components, and the significance of each component varies greatly. There is a need for more systematic information about the natural history of burnout in specific work situations. Nurse administrators are urged to be alert for sings of burnout among their nursing personnel, to encourage systematic research that will provide objective evidence of the problem, and, especially, to be creative and daring in their efforts to combat the problem. PMID- 6915082 TI - Accurate measurement of nursing turnover: the first step in its reduction. PMID- 6915083 TI - Practical suggestions for applying to doctoral programs. PMID- 6915085 TI - Acquiring political clout: guidelines for nurse administrators. PMID- 6915084 TI - Working together: a positive experience in service-education collaboration. AB - The participants in this interview agree that university schools of nursing must maintain realistic and relevant programs in administration. There is a need for active involvement of practicing administrators in the design of nursing administration curricula. Administrators must also learn to involve faculty in identifying the roles of nursing care organizations in a changing health care delivery system. Directors of nursing must be willing to "open the door" to educators seeking practice opportunities. The result can be positive relationships that mutually benefit both nursing education and the delivery of care. PMID- 6915086 TI - How to get a good consultant. PMID- 6915087 TI - Managing your own time: the most important management task. PMID- 6915088 TI - Promoting practice-based research: a critical need. PMID- 6915090 TI - Taking the pain out of writing objectives. PMID- 6915089 TI - Mastering the art of planning by committee. PMID- 6915091 TI - An absenteeism control program. PMID- 6915092 TI - Essential elements of nurse-physician collaboration. PMID- 6915094 TI - The meeting chairperson: master or servant? PMID- 6915093 TI - Evaluating bicultural training. PMID- 6915095 TI - Research policy for nursing services: Part 2. PMID- 6915096 TI - The publication of nursing research. PMID- 6915097 TI - Nonsteroidal anti-inflammatory agents - Part I. PMID- 6915099 TI - Porphyria: nursing needs for an uncommon condition. PMID- 6915098 TI - A cancer primer. PMID- 6915100 TI - The problem patient: a manipulative mother. PMID- 6915101 TI - Heat transfer and thermal dosimetry. PMID- 6915102 TI - Direct contact applicators for microwave hyperthermia. PMID- 6915103 TI - Clinical hyperthermia systems engineering. PMID- 6915104 TI - Clinical hyperthermia trials: design principles and practice. AB - The initial development of a significant risk device is predicated upon demonstrable medical need and an adequate biophysical rationale. Although microwave and radiofrequency thermotherapy systems strongly meet these requirements, their clinical evaluation has often suffered from inadequate or inappropriate preclinical laboratory experimentation. It is suggested that devices be tested in animals rather than phantoms and that thermal profiles, cooling curves, power vs. temperature studies et al be carried out in the organ or organs of interest. Clinical trials can then be designed in which an attempt is made to replicate laboratory measurements in humans in order to develop physical dose-response relationships and toxicity data (i.e. a phase-I or feasibility study). The experimental paradigm for clinical drug testing can also be applied, with some modifications, to the further evaluation of devices for the determination of therapeutic response rates (phase-II) and for controlled evaluation against available treatments in a homogeneous patient population (phase-III). It is extremely important that early clinical trials not be contaminated by the possible effects of other concurrent therapies and that sophisticated statistical design be employed to protect human subjects from unnecessary exposure to experimental treatments. The ethical issues involved are best dealt with by good scientific design. PMID- 6915105 TI - Clinical evaluation of a microwave/radiofrequency system (BSD Corporation) for induction of local and regional hyperthermia. AB - The technical aspects of an experience with clinical hyperthermia utilizing the BSD-1000 and BDS annular phased array applicator are reviewed. The design and operation of the basic console functions of the BSD apparatus relating to temperature data presentation and recording and computer control leave little need for significant improvement. Such improvements as may eventually be desired can probably be made as software changes in the computer programs. The 100 W generator capacity is occasionally inadequate to drive even a single applicator and certainly inadequate to supply multiple applicator arrays or larger low frequency applicators. Amplifiers will eventually be added for the frequency ranges of greatest interest. The temperature probes and utilization routines have been excellent but their diameter is undesirably large. However, the design of the basic instrument is such that improved smaller probes and systems for dynamic temperature sampling matrices can be interfaced readily. Due to the limited superficial volumes that can be presently heated with this device, most important potentially curable tumors cannot be treated. Possible important exceptions to this are a number of sites in the upper respiratory tract. The depth and superficial extent of heatable volumes may be moderately extended with increased power, appropriate study of applicator arrays and new applicator designs. Provisions for surface temperature control are important and will need to be incorporated. The annular phased array applicator, though still a prototype design, has demonstrated encouraging results regarding its possible use for regional heating of central abdominal and thoracic tumors. Improvements in "human engineering" and study of the effects and implications of departures from basic cylindrical anatomy are required and are in progress. The improved sophistication in temperature sampling techniques described is considered important for adequate monitoring of temperature gradients in the abdomen and chest. PMID- 6915106 TI - Some practical considerations for the use of localized hyperthermia in the treatment of cancer. AB - Practical considerations in the selection and administration of microwave and RF induced hyperthermia in the treatment of various tumors are discussed. A thorough knowledge of the thermal properties of the tumor and its environment is required for the establishment of an effective therapeutic regimen. Examples of clinical observations illustrate the patients' general tolerance to the therapy and highlight the problems presented by some special cases. Possible ways of avoiding adverse effects during localized microwave induce heating of superficial tumors and RF heating of deep seated tumors are described. PMID- 6915107 TI - United States radiation safety and regulatory considerations for radiofrequency hyperthermia systems. AB - The control of Radiofrequency (RF) radiation (including microwave radiation) that is emitted by therapeutic medical devices is the responsibility of the Food and Drug Administration's (FDA) Bureau of Radiological Health (BRH). Several studies of RF emissions from various shortwave (27 MHz) and microwave (2450 MHz) diathermy devices have been conducted by the Electromagnetics Branch of the Bureau's Division of Electronic Products. BRH studies have led to a proposed standard for microwave diathermy devices operating above 900 MHz. Shortwave diathermy devices used in physical therapy situations have been found to produce relatively high levels of unintended exposures (sometimes exceeding present U.S. exposure standards) to device operators and to the nonprescribed tissues of the patient. BRH is initiating further studies to ascertain the need for controls to be placed on these shortwave devices to ensure safety and medical effectiveness. Radiation safety standards, which presently exist in the United States, allow much higher unintended human exposures than do the standards existing in the several eastern European countries. A trend to lower permissible exposures to 5 mW/cm2 or even 1 mW/cm2 is under way in the U.S. The various provisions of FDA's Medical Device regulations apply to investigational as well as commercially marketed RF/microwave devices and require both safety and medical effectiveness aspects of performance to be addressed by their manufacturer. A set of microwave radiation safety considerations has been developed by BRH for newly emerging cancer therapy protocols which utilize microwave hyperthermia devices. PMID- 6915108 TI - Hyperthermia-research supported by the National Cancer Institute. PMID- 6915110 TI - Nursing education a major thrust. PMID- 6915109 TI - Nafcillin-tolerant Staphylococcus epidermidis endocarditis. PMID- 6915111 TI - Socio-economic welfare of Jamaican nurses: highlights of NAJ accomplishments. PMID- 6915113 TI - Health for all by the year 2000. World Health Day. PMID- 6915115 TI - Role of the community health worker. PMID- 6915112 TI - The management of change. PMID- 6915116 TI - [Evaluation of urinary kallikrein assay by using chromogenic peptide substrates (I) (author's transl)]. PMID- 6915114 TI - Health for all: principal strategies. PMID- 6915117 TI - [Customs related to delivery and infant care in Kyoto--from conception to the infants' first visit to the temple]. PMID- 6915118 TI - [Clinical course and nursing of a pregnant patient with ileostomy]. PMID- 6915119 TI - [Asherman's syndrome]. PMID- 6915121 TI - [Development of maternal behaviors]. PMID- 6915120 TI - [Fetal diagnosis and medical ethics]. PMID- 6915122 TI - [Mother-child relationship in the early stage of infancy]. PMID- 6915124 TI - [Apprehension of mothers before and after delivery]. PMID- 6915123 TI - [Behavioral development in early infancy--a basis of the establishment of mother child relations]. PMID- 6915126 TI - [The effects of maternal smoking on infants]. PMID- 6915125 TI - [Maturation process in maternal behavior]. PMID- 6915128 TI - [Management of premature abruption of the normal placenta]. PMID- 6915129 TI - [A letter from the U.S.A. Vacation]. PMID- 6915130 TI - [Toxic shock syndrome]. PMID- 6915127 TI - [Instructions and practical training in infant bathing at the gyneco-obstetrical department and future direction in patient education]. PMID- 6915132 TI - [New plasma exchange method]. PMID- 6915131 TI - [Lamaze method of delivery and an experience by the husband and wife]. PMID- 6915134 TI - [Physiopathology and surgical indication in rheumatoid arthritis]. PMID- 6915133 TI - [Salt-dependence of blood pressure and urinary kallikrein excretion in essential hypertension (author's transl)]. PMID- 6915135 TI - [Physiopathology and surgical indication in osteoarthritis]. PMID- 6915136 TI - [Pre- and postoperative care of patients with rheumatoid arthritis]. PMID- 6915137 TI - [Pre- and postoperative care of patients with osteoarthritis]. PMID- 6915138 TI - [Rehabilitation therapy of rheumatoid arthritis and osteoarthritis]. PMID- 6915139 TI - [Pre- and postoperative nursing care in total joint replacement]. PMID- 6915140 TI - [Prevention of infections following joint replacement: aseptic care, wound protection, and an innovation of protective clothing]. PMID- 6915142 TI - [Nursing of patients with chronic rheumatoid arthritis--nursing actions through surgical therapy and physical therapy for functional recovery]. PMID- 6915141 TI - [Rehabilitation nursing and various problems involving patients with total hip joint replacement]. PMID- 6915143 TI - [Nursing of a patient with a low IQ who has undergone total replacement of the right hip joint]. PMID- 6915144 TI - [An innovation in bedpans for unassisted urination--an example with a patient with rheumatoid arthritis who has been unable to walk for the past 35 years]. PMID- 6915145 TI - [A clinical conference. Nursing actions and follow-up of a rheumatoid arthritis patient with knee joint replacement]. PMID- 6915148 TI - [Classification and physiopathology of dehydration]. PMID- 6915149 TI - [Science of symptomalogy: dehydration. Osmotic pressure of body fluids and control of its volume]. PMID- 6915147 TI - [Introduction of ultrasonics in determination of urinary specific gravity]. PMID- 6915146 TI - [Care in urination of a patient with a prolonged consciousness disorder- prevention of obstruction in an indwelling catheter]. PMID- 6915150 TI - [Prevention of dehydration in a child with acute diarrhea]. PMID- 6915151 TI - [Nursing problems with drip infusions in a child with dehydration]. PMID- 6915152 TI - [On meeting the needs of the patient: a patient's view]. PMID- 6915154 TI - [Epidemiological overview on cancer of the large intestine]. PMID- 6915153 TI - [Cardiac emergency]. PMID- 6915155 TI - [Early discovery of cancer of the large intestine--early diagnosis and keypoints]. PMID- 6915156 TI - [Long term follow-up after surgery of cancer of the large intestine--functional disorders (complications) and their management]. PMID- 6915157 TI - [Postoperative sexual dysfunction in patients with cancer of the large intestine- the conditions and its management]. PMID- 6915159 TI - [Nursing problems and management of patients with cancer of the large intestine- nursing of patients with postoperative urination disorders]. PMID- 6915158 TI - [Postoperative dysfunctions of patients with colostomy--with special reference to the care in urination disorders]. PMID- 6915160 TI - [Intestinal disorders and control of defecation following resection of the large intestine]. PMID- 6915163 TI - [Science of symptomatology: deglutition disorders. Physiology of deglutition and pathogenesis of its dysfunction]. PMID- 6915162 TI - [Aftercare of patients with colostomy who report sexual disability--nursing limitations in the involvement with organizations of patients with colostomy]. PMID- 6915161 TI - [Assistance in independent urination by patients with cancer of the large intestine after surgery]. PMID- 6915164 TI - [Science of symptomatology: deglutition disorders. Etiology, therapy, and management of deglutition disorders]. PMID- 6915165 TI - [Mealtime assistance of a patient with maxillary cancer being treated with a combination of surgery, radiation and chemotherapy]. PMID- 6915166 TI - [Feeding behavior and nursing of a child with highly limited mouth opening due to Nager's syndrome (acrofacial dysostosis)]. PMID- 6915167 TI - [Pre- and postoperative nursing of ileostomy patients]. PMID- 6915169 TI - [Iatrogenic disease as an aporia of modern medicine]. PMID- 6915168 TI - [Postoperative complications and their prediction in abdominal surgery. (1)]. PMID- 6915170 TI - [Disharmony among the medical team and iatrogenic disease]. PMID- 6915171 TI - [Medically related professions, relationship with patients, and iatrogenic diseases. Attitudes of physicians and nurses and anxiety of the patient]. PMID- 6915172 TI - [Medically related profession, relationship with patients, and iatrogenic diseases. Patients' personality and their prior knowledge of illness]. PMID- 6915173 TI - [Iatrogenic diseases caused by diagnostic tests and their prevention]. PMID- 6915174 TI - [Iatrogenic diseases caused by medication and their prevention]. PMID- 6915175 TI - [Iatrogenic diseases caused by radiotherapy and their prevention]. PMID- 6915176 TI - [Iatrogenic diseases related to surgical treatment and their prevention]. PMID- 6915178 TI - [For elimination of so-called "iatrogenic disease"]. PMID- 6915177 TI - [Various forms of iatrogenic diseases and their prevention. Nursing in intensive care]. PMID- 6915181 TI - [Problems concerning terminal care-with special reference to the care at the hospice]. PMID- 6915180 TI - [Crises in health and medicine]. PMID- 6915179 TI - [On "dehospitalization"]. PMID- 6915182 TI - [Grey zone of the mind]. PMID- 6915183 TI - [Significance of publication of research results]. PMID- 6915184 TI - [Conference: odor prevention at a gynecologic ward - experimental qualitative and quantitative tests using activated charcoal]. PMID- 6915185 TI - [Conference: a review of the study on prevention of odors in a gynecological ward]. PMID- 6915186 TI - [Observation on accurate subcutaneous and intramuscular injections]. PMID- 6915187 TI - [Selection of a research theme]. PMID- 6915188 TI - [Controversial items in American nursing - in search of nursing theories and methodology characteristic to Japan]. PMID- 6915189 TI - [Retraining of inactive nurses]. PMID- 6915190 TI - [Learning in nursing and related matters]. PMID- 6915191 TI - [Interactions between the students and instructors in clinical training (2)]. PMID- 6915193 TI - [Assistance in daily activities of schizophrenic patients with illusions and fantasy]. PMID- 6915192 TI - [The concept of the family in nursing education: the results of a survey and the attitudes of nursing students]. PMID- 6915194 TI - [In search of a welfare system suitable for the society (4). A key to bring out sensitivity of the opponent]. PMID- 6915195 TI - [Minerva's light: an unassumed thought on nursing and man. (10). Unique quality of Japanese and nursing]. PMID- 6915196 TI - [A joint effort in fight against cancer]. PMID- 6915197 TI - [In-service education in the hospital and the role of the head nurse]. PMID- 6915199 TI - [Progress of the Japanese Association of Nursing Education: contribution to nursing education in the past 30 years]. PMID- 6915198 TI - [Start of the Japanese Society of Nursing Science]. PMID- 6915200 TI - [Progress of the Japanese Nursing School Conference: improvement of nursing schools]. PMID- 6915201 TI - [Laws and nursing education. Discussion]. PMID- 6915202 TI - [Planning of training in midwifery technics and its application in midwifery schools. 1. Educational planning]. PMID- 6915203 TI - [Stability of the attendants of nursing instructors' seminar: 77.5% of those who retired wish to return to nursing]. PMID- 6915204 TI - [In search of a welfare system suitable for the society (5). The basis of compassion]. PMID- 6915205 TI - [Minerva's light. An unassumed thought on nursing and man. (11). Precious smile of a mother suffering from cancer]. PMID- 6915206 TI - [Enlightening moments in the interactions of a physician and patients]. PMID- 6915207 TI - [My wishes for nursing education]. PMID- 6915209 TI - [Evaluation of a study plan in comprehensive nursing: a unified approach in nursing technology]. PMID- 6915208 TI - [Learning in nursing and related matters. (2)]. PMID- 6915210 TI - [Interactions between the students and instructors in clinical training. (1)]. PMID- 6915212 TI - [In search of a welfare system suitable for the society (3). Capacity to understand the unspoken appeal]. PMID- 6915211 TI - [Self-evaluation in teaching of anatomy - in relation to the contents of the national examination]. PMID- 6915213 TI - [Minerva's light: an unassumed thought on nursing and man. (9). A support in a fight against cancer]. PMID- 6915214 TI - [Good and bad children in the adult's eye]. PMID- 6915215 TI - [Continuation and development of public health nursing activities maintained by the senior nurses--the problem of work succession observed in 3 examples]. PMID- 6915217 TI - [Progress in public nursing activities at Kumamoto]. PMID- 6915216 TI - [Problems of continuation of public health nursing activities by the succeeding nurses. Discussion]. PMID- 6915218 TI - [Assistance of a child in the process of adjusting to the home environment after an extended stay at a hospital (2)]. PMID- 6915219 TI - [A trial in systematization of basic nursing and public health nursing education- adult nursing in comprehensive training in the basic course]. PMID- 6915220 TI - [Public health nursing activities in London: 1 day of Ms. Beck]. PMID- 6915221 TI - [Turning point in regional psychiatric care in the United States]. PMID- 6915224 TI - [Living conditions of patients with sequelae of apoplexy after discharge and their relationship with the persons in charge of nursing--the relationship to their ADL]. PMID- 6915222 TI - [An area surrounded by the Aso Mountains in Kyushu--8 years of public health nursing activities in an isolated area]. PMID- 6915223 TI - [Evaluation of health status survey of an organization of the aged and health education of the members]. PMID- 6915225 TI - [Changes in blood pressure prior to apoplexic attacks]. PMID- 6915230 TI - [Health centers in England]. PMID- 6915228 TI - [Reflection on my life as a public health nurse]. PMID- 6915226 TI - [Evaluation of prophylaxis of apoplexy using an apoplexy registry]. PMID- 6915227 TI - [On nursing needs observed in the care of a patient with sequelae of apoplexy who has no desire for recovery]. PMID- 6915231 TI - [A trial in regional mental health activities. A process of occupational rehabilitation of a young man who was accused of absenteeism and violence by his family and has retreated at home--re-evaluation of the approach taken in cooperation with the family, employer, and medical personnel]. PMID- 6915232 TI - [3 years of public health psychiatric nursing activities supporting a young man with a mental disorder and his mother. A discussion]. PMID- 6915229 TI - [Assistance for a schizophrenic housewife and her family. (1)]. PMID- 6915233 TI - [National Health Service in Scotland and Denmark. (2). A visit with Dr. Koonsberg]. PMID- 6915234 TI - [Symposium: regional status of chronic diseases: an example in kidney diseases]. PMID- 6915235 TI - [Discussion: chronic diseases originating in infancy and childhood and becoming evident during productive adult life: an objective of public health nursing activities]. PMID- 6915236 TI - [A trial in systematization of basic nursing and public health nursing education obstetrical and pediatric nursing in comprehensive training in the basic course]. PMID- 6915237 TI - [Assistance of a child in the process of adjusting to the home environment after an extended stay at a hospital (1)]. PMID- 6915238 TI - [Effects and the problems of measures for prevention of apoplexy at the Kihoku area, Ehime Prefecture]. PMID- 6915239 TI - [Activities by the Akabane Public Health Office concerning prevention of adult diseases]. PMID- 6915241 TI - [Iatrogenic incidents related to nursing. 9. Bacterial infections]. PMID- 6915240 TI - [Tough ladies of Edinburgh: activities of district nurses]. PMID- 6915242 TI - [Medical topics. Estrogens and endometrial cancer]. PMID- 6915243 TI - [Medical topics. Biotin deficiency]. PMID- 6915244 TI - [Legionnaires' disease]. PMID- 6915245 TI - [Diary of home nursing: problems of a patient with juvenile diabetes mellitus and his family]. PMID- 6915247 TI - [Nursing in the European community. Nursing in Denmark]. PMID- 6915246 TI - [Continued nursing education in the United States and the problems in Japan]. PMID- 6915248 TI - [Statistical files. Utilization of public health nurses: prefectural and other statistics]. PMID- 6915250 TI - [Social position and evaluation of nurses in the modern history of nursing in Japan]. PMID- 6915249 TI - [Diagnosis and the attitude of the physician]. PMID- 6915251 TI - [Nursing in the European Community: nursing in Germany]. PMID- 6915252 TI - [Continuing nursing education in the United States and the problems in Japan]. PMID- 6915253 TI - [Statistical file. The number of facilities for nursing education: prefectural and other area statistics]. PMID- 6915255 TI - [The people I admire most]. PMID- 6915254 TI - [Interactions with mothers in public health services]. PMID- 6915257 TI - [A study on the development of nursing courses]. PMID- 6915256 TI - [Obstetrical nursing in health education in schools - assistance of high schools girls in preparation to become mothers]. PMID- 6915258 TI - [Maternal behavior and nursing]. PMID- 6915259 TI - [Study on the social position and evaluation of nurses of the modern history in Japan]. PMID- 6915260 TI - [Diary of home nursing: on a schizophrenic patient]. PMID- 6915261 TI - [A profile of a nurse. Ms. Yuki Kobayashi, Executive Director of the Japanese Nursing Association under a new system]. PMID- 6915263 TI - [Medical topics. Hyperthermia]. PMID- 6915262 TI - [Medical topics. Habitual use of laxatives]. PMID- 6915267 TI - [Theory and practice of the nursing process]. PMID- 6915265 TI - [Analysis of the evaluation of nursing services-related departments in connection with hospital accreditation. Korean Hospital Association]. PMID- 6915264 TI - [Standards of hospital nursing services]. PMID- 6915266 TI - [Opinion on hospital accreditation services]. PMID- 6915268 TI - [Critical care nursing. Patient evaluation and initial care]. PMID- 6915269 TI - [Cardiac arrest and cardiopulmonary resuscitation]. PMID- 6915270 TI - [A survey of the inservice education program of General Hospital in Seoul. Education and Research Committee, Seoul Branch]. PMID- 6915271 TI - [Significance of Hospital Accreditation Services and standards of nursing services]. PMID- 6915272 TI - [Wall care unit]. PMID- 6915273 TI - [Pathogenesis of hypertension]. PMID- 6915275 TI - [Advantages and disadvantages of aging]. PMID- 6915276 TI - Dental health education rhetoric or reality? PMID- 6915277 TI - Fluoride programs in the school setting: preventive dental health. PMID- 6915274 TI - [Legasthenia - phantom or reality?]. PMID- 6915279 TI - A mixed message: the school vending machine. PMID- 6915278 TI - Competing with Ronald McDonald, Cap'n Crunch and the Pepsi generation. PMID- 6915280 TI - Evaluating school dental health education programs. PMID- 6915282 TI - Dental myths: a baker's dozen. PMID- 6915281 TI - The humanistic approach: a model for dental health curriculums. PMID- 6915283 TI - Activities for National Children's Dental Health Month. PMID- 6915284 TI - The relationship between dietary factors and dental caries. PMID- 6915285 TI - First aid procedures for dental emergencies. AB - If a child suffers a dental injury, provide temporary relief where possible and consult a dentist as soon as possible. It should not be difficult to obtain an emergency dental appointment; however, if difficulties do arise, contact your local dental society. They often have dentists on emergency call 24 hours a day. If a dentist cannot be contacted immediately, an attending physician in an emergency room should know how to handle an acute dental or oral injury. Although temporary relief can be provided in most dental emergencies, this does not alleviate all symptoms. When in doubt, consult a dentist as soon as possible. PMID- 6915286 TI - Generating superintendent support for school preventive dental programs. PMID- 6915288 TI - Sources of dental health teaching aids. PMID- 6915289 TI - Industry-sponsored dental health teaching aids: selection criteria and program examples. PMID- 6915287 TI - The need for dental health screening and referral programs. AB - School-based dental health screening and referral programs can have a tremendous impact on a community. They provide examinations to children, some of whom have never seen a dentist, and refer those in need of treatment. When coordinated with other dental health activities, these programs can also raise the overall consciousness about oral health and need for health care in children and parents alike. By their concern for dental health and encouragement to the children to participate in the screening programs and follow through on referrals, school officials can serve as role models to the children and further reinforce the importance of dental health. By conducting the screenings on a local level, the problem is seen as a community one, and is more likely to be meaningfully addressed. School officials, health personnel and teachers are instrumental in initiating and conducting these programs and are thus responsible for the benefits the children derive from the screenings. PMID- 6915292 TI - [The concept of information science]. PMID- 6915291 TI - An evaluation of the effects of the American Dental Association's dental health education program on the knowledge, attitudes and health locus of control of high school students. PMID- 6915290 TI - Tobacco use and oral health. PMID- 6915293 TI - [Serialization of collection of nursing information]. PMID- 6915294 TI - [Process of extraction of nursing problems--an attempt at description of the record]. PMID- 6915297 TI - [The current status and future direction in the nurses' interest toward patients' families at clinical scenes]. PMID- 6915296 TI - [Possible automation of nursing information processing]. PMID- 6915295 TI - [Significance of nursing information in the nursing process--with special reference to nursing evaluation]. PMID- 6915298 TI - [Bedside conference: planning of clinical training (10). The blood (2)]. PMID- 6915299 TI - [Industrial organization and communication]. PMID- 6915301 TI - [Elements of psychological assessment: 10 elements which make up an electric approach to psychological assessment]. PMID- 6915300 TI - [A viewpoint on clinical training (2)]. PMID- 6915302 TI - [A trial in clinical training to inspire sympathetic understanding]. PMID- 6915303 TI - [In search of new nursing philosophy. XI. 3 elements in nursing]. PMID- 6915304 TI - [Interactions with patients with phonation and articulation disorders--a lesson in non-verbal communication]. PMID- 6915305 TI - [Test yourself. Nursing of a patient with brain tumor]. PMID- 6915306 TI - [Clinical essay. True nursing]. PMID- 6915308 TI - [Diagnosis and treatment of subdural hematoma]. PMID- 6915307 TI - [Subdural hematoma]. PMID- 6915310 TI - [Nursing of patients with subdural hematoma: evaluation of the nursing process. A discussion]. PMID- 6915312 TI - [Rest and assistance in activities of daily living of a child with nephropathy]. PMID- 6915314 TI - [Nursing and therapy: rehabilitation equipment (2). Canes and walkers: their uses and notes on patient instructions]. PMID- 6915313 TI - [Rest and assistance in exercises by cardiac patients--nursing actions in the hygienic care during the acute stage, assistance in rehabilitation in the recovery period, and guidance on daily activities of patients with myocardial infarction]. PMID- 6915315 TI - [Nursing and therapy: rehabilitation equipment (2). Assistance for patients requiring supportive equipment and canes]. PMID- 6915309 TI - [Nursing process for patients with subdural hematoma]. PMID- 6915311 TI - [Rest: re-evaluation of its significance]. PMID- 6915317 TI - [Assistance of a patient with pregnancy toxemia and the nursing personnel]. PMID- 6915316 TI - [Nursing process: possibilities and limitations in its application (4). Evaluation of the procedure in each process: assessment (3)--assessment of the problem of each case]. PMID- 6915318 TI - [Nursing process/nursing of patients with muscular dystrophy. Definition of muscular dystrophy]. PMID- 6915319 TI - [Nursing process/nursing of patients with muscular dystrophy. Diagnosis and therapy of muscular dystrophy]. PMID- 6915320 TI - [Nursing process/nursing of patients with muscular dystrophy. Nursing of patients with Duchenne type muscular dystrophy]. PMID- 6915321 TI - [Nursing process/nursing of patients with muscular dystrophy. A case study and nursing of a patient with Duchenne type muscular dystrophy]. PMID- 6915322 TI - [Nursing process/nursing of patients with muscular dystrophy. Evaluation of the nursing process. Discussion]. PMID- 6915323 TI - [Current status of postoperative infections and their prevention]. PMID- 6915325 TI - [Nursing seminar: prophylaxis of infection (1). Nursing approach in the prevention of hospital infections]. PMID- 6915327 TI - [Nursing and therapy: rehabilitation equipment (3). Orthopedic support: types and indications]. PMID- 6915324 TI - [Evaluation of sterilization of the intratracheal catheters and antisepsis of the fingers--an experimental study]. PMID- 6915326 TI - [Nursing process: possibilities and limitations of its planned application (5). Evaluation of the procedures in each stage: assessment (3)--comprehension of individual problems]. PMID- 6915328 TI - [Nursing and therapy: rehabilitation equipment (3). Assistance of patients requiring walking support (orthopedic support)]. PMID- 6915329 TI - [Assistance of patients during weaning from the respiratory and nursing personnel]. PMID- 6915330 TI - ["Good nursing" and the nursing system]. PMID- 6915331 TI - [A trial in instruction on self-examination of breast cancer--1. Problems observed in the analysis of the results of questionnaires]. PMID- 6915332 TI - [Test yourself. Nursing of schizophrenic patients]. PMID- 6915333 TI - [Clinical essay. Occasional thoughts on nursing]. PMID- 6915334 TI - The psychiatric nurse's duty to warn potential victims of homicidal psychotherapy outpatients. PMID- 6915335 TI - Delivery rooms: for women only? PMID- 6915336 TI - Pathophysiological factors in chronic pancreatic diseases. PMID- 6915337 TI - [Clinical aspects, diagnosis and treatment of rectal cancer]. PMID- 6915339 TI - [Anti-inflammatory x-ray therapy]. PMID- 6915340 TI - [Role of the nurse in caring for cardiology patients]. PMID- 6915338 TI - [Osteomyelitis]. PMID- 6915341 TI - [Postoperative patient care in nonspecific ulcerative colitis]. PMID- 6915342 TI - [Work of the nurse in the suppurative surgery department]. PMID- 6915343 TI - [Current diagnostic methods in myeloma disease]. PMID- 6915344 TI - [Therapeutic use of diadynamic currents]. PMID- 6915346 TI - [Endoscopy in gastroenterology]. PMID- 6915345 TI - [Work of the nurse in the hyperbaric oxygenation department]. PMID- 6915347 TI - [Blood transfusions and component therapy in clinical practice]. PMID- 6915348 TI - [Hemosorption in clinical practice]. PMID- 6915349 TI - [Treatment of myeloma disease]. PMID- 6915350 TI - [Premature child. 3. Care of the premature child at home]. PMID- 6915351 TI - [Initiation into the profession]. PMID- 6915352 TI - [Diagnosis and treatment of gastroduodenal ulcers complicated by hemorrhage]. PMID- 6915353 TI - [Nurse participation in the treatment of traumatic shock]. PMID- 6915354 TI - [Post-transfusion complications]. PMID- 6915355 TI - [Maintenance of a sanitary epidemiological routine in the operating room]. PMID- 6915356 TI - [Endocardial fibroelastosis in infants]. PMID- 6915357 TI - [Use of sombrevin in the polyclinic]. PMID- 6915358 TI - [Work of the inoculations room in a pediatric polyclinic]. PMID- 6915359 TI - [Dispensary care of children with surgical pathology]. PMID- 6915360 TI - [Nurse's work in the adolescent medicine office]. PMID- 6915361 TI - [Nurses' duties in physiotherapy departments]. PMID- 6915363 TI - [Health and hygiene regimen in the hospital admitting department]. PMID- 6915364 TI - [Improving the qualifications of paramedical personnel]. PMID- 6915362 TI - [Organization of diet therapy in a city hospital]. PMID- 6915365 TI - [Because I love it]. PMID- 6915366 TI - [Name of the feat is humanism]. PMID- 6915368 TI - [Deontology of the nurse]. PMID- 6915367 TI - [Deontology in the x-ray department]. PMID- 6915369 TI - [Health bulletin in industrial enterprises]. PMID- 6915370 TI - [Wall newspaper in educating medical personnel]. PMID- 6915371 TI - [Our nurses' council]. PMID- 6915372 TI - [Care of ischemic heart disease patients]. PMID- 6915374 TI - Perils, pitfalls, priorities, processes, and problems in preparing for accreditation. PMID- 6915373 TI - Care of the Mexican-American patient. PMID- 6915375 TI - Who precepts the preceptor? PMID- 6915376 TI - Recommending adult day care centers. PMID- 6915377 TI - All malpractice coverage is not the same: personal vs. blanket liability coverage. PMID- 6915378 TI - Nursing diagnoses for healthy individuals. PMID- 6915379 TI - From whence accountability? PMID- 6915380 TI - Educational/career mobility: antecedent of change. PMID- 6915381 TI - Nursing home ombudsman. PMID- 6915382 TI - Associate degree nursing education: past, present, and future. PMID- 6915383 TI - Cultural concepts and postpartal care. PMID- 6915384 TI - Power, tactics, and the professionalization process. PMID- 6915385 TI - Unification: nursing education and nursing practice. PMID- 6915386 TI - Clinical nurse specialist role development. PMID- 6915388 TI - The lack of effective faculty role models within professional schools. PMID- 6915387 TI - Health promotion by nursing in care of the elderly. PMID- 6915389 TI - Teaching male catheterization: an application of change theory for an entire nursing staff. PMID- 6915390 TI - Games with goals. PMID- 6915391 TI - The birth, life and times of a clinical evaluation tool. PMID- 6915392 TI - Renewal--a positive outcome of faculty evaluation. PMID- 6915393 TI - RN-BSN education: helping RNs make tough decisions. PMID- 6915394 TI - Test your knowledge: preview the new state boards. PMID- 6915395 TI - Deciphering diagnostic studies: white blood cell tests. PMID- 6915397 TI - Think you know septic shock? PMID- 6915399 TI - Fear of floating--to neurology. PMID- 6915396 TI - Challenge: Peter's sore--is it dangerous? PMID- 6915398 TI - When persistence pays off: resolving the mystery of an unexplained electrolyte imbalance. PMID- 6915401 TI - I.C.U. psychosis: helping your patient return to reality. Nursing grand rounds. PMID- 6915400 TI - Ambulatory nursing: a guide to your patient's safe home use of oxygen. PMID- 6915402 TI - Update your technique for changing dressings: dry to dry. PMID- 6915405 TI - Common cold. PMID- 6915403 TI - A tool for assessing the real world of diabetic noncompliance. PMID- 6915406 TI - Drug challenge: drug combinations. PMID- 6915407 TI - Skillcheck: on assessing shock. PMID- 6915408 TI - Skillcheck: on assessing cardiac function. PMID- 6915409 TI - Drug challenge: drug combinations. PMID- 6915410 TI - Urinalysis: a common test, but never routine. PMID- 6915412 TI - Test your knowledge of the multiple trauma patient. PMID- 6915411 TI - Pharmacist on call: sodium nitroprusside: fast-acting antihypertensive. PMID- 6915414 TI - Medication errors: calculate doses on paper--not in your head. PMID- 6915413 TI - Sharing: taking things for granted. PMID- 6915415 TI - Holding out hope to your dying patient--paradoxical but possible. PMID- 6915416 TI - Fear of floating to emergency department. PMID- 6915417 TI - Dorothy enjoyed her reputation as a mean old lady. PMID- 6915418 TI - Pulmonary hypertension. PMID- 6915419 TI - Update your technique for changing dressing: wet to dry. PMID- 6915421 TI - Deciphering diagnostic studies: amniotic fluid analysis. PMID- 6915420 TI - Seeking and finding all those patients with high blood pressure. PMID- 6915422 TI - Would you administer placebos for pain? PMID- 6915424 TI - An expanded conceptualization of job satisfaction and career style. PMID- 6915423 TI - Placebo misuse. PMID- 6915425 TI - Role negotiation: a strategy for facilitating an interprofessional health care team. PMID- 6915426 TI - A framework for measuring satisfaction of nursing staff. PMID- 6915427 TI - The leader as decision maker. PMID- 6915428 TI - The new midwifery. Community midwife: the gentle approach. Interview by C. Fairbrother. PMID- 6915429 TI - The new midwifery. Hospital midwife: care through technology. Interview by S. Comer. PMID- 6915430 TI - Salmon - 15 years on. Interview by C. Webb. PMID- 6915431 TI - White versus colorful: nurses uniforms come in all sizes - and styles - and colors. PMID- 6915432 TI - Recruiter strings two careers together. Interview by Helen Donigan. PMID- 6915433 TI - The trauma admitting nurse: her domain is a walk-in crash cart. PMID- 6915434 TI - Trauma nursing. Life Flight: a high flying operation. PMID- 6915435 TI - Focus on CE. Life-long learning: a question of motivation? PMID- 6915436 TI - EDNA: Emergency Department Nurses Association. PMID- 6915437 TI - Alcoholism: what can the OH service do? PMID- 6915438 TI - The price of a pint. PMID- 6915440 TI - Safety: machinery safety--reinventing the wheel. PMID- 6915441 TI - Colour vision at work. PMID- 6915439 TI - The OH approach in Greece. PMID- 6915442 TI - Health assessment of the cardiovascular patient. PMID- 6915444 TI - Atherosclerotic occlusive arterial disease: promotion of optimal health. PMID- 6915445 TI - Chest pain due to angina. PMID- 6915443 TI - Occupational health nursing and cardiovascular clients: 1981-2001 A.D. PMID- 6915446 TI - Non-cardiac origins of chest pain. PMID- 6915447 TI - Current concepts of cardiac rehabilitation. PMID- 6915448 TI - A realistic method of health hazard appraisal for the occupational health nurse. PMID- 6915449 TI - Psychiatric disorders in the work setting: identification & management of the manic individual. PMID- 6915450 TI - Practical application of a breast self-examination program in the industrial setting. PMID- 6915451 TI - The occupation health nurse's role in rehabilitation. PMID- 6915452 TI - Promotion of self-care in the employee with rheumatoid arthritis. PMID- 6915456 TI - [Communication in the hospital]. PMID- 6915453 TI - [Anxiety or information in the hospital. 3. Role of nursing personnel]. PMID- 6915454 TI - [Alcoholism and drug dependence - role of nursing personnel]. PMID- 6915455 TI - [Dental prophylaxis. 2. Active dental prophylaxis with a healthy diet]. PMID- 6915457 TI - [Assistance in everyday management]. PMID- 6915458 TI - Directing: the interpersonal aspect of management. PMID- 6915460 TI - Primary health care: Philippine policy paper. PMID- 6915462 TI - The rehabilitation of road accident victims. PMID- 6915459 TI - Two models on primary health care approach of Region VII. PMID- 6915461 TI - Decision-making. PMID- 6915463 TI - Rehabilitation of patients with traumatic cord lesions. PMID- 6915464 TI - Physiotherapy in Singapore. PMID- 6915465 TI - Medical services for the elderly - a view. PMID- 6915466 TI - Professional social responsibility to elders. PMID- 6915467 TI - Children in the 80s - problems and prospects. PMID- 6915468 TI - Managing family stress. PMID- 6915469 TI - Primary health care - to search the health strategies in the 80s. PMID- 6915470 TI - Perspectives in health and the family. PMID- 6915471 TI - Forging ties: partners with the public - patient and client. PMID- 6915474 TI - Heat exhaustion. PMID- 6915472 TI - Urinary tract stones - urolithiasis. PMID- 6915473 TI - Assisted ventilation. PMID- 6915475 TI - The rubella immunity of women of child-bearing age in Singapore. PMID- 6915476 TI - Social services in Singapore and society's role in this sphere. PMID- 6915477 TI - Medical advances and moral problems. PMID- 6915478 TI - Nurse and aide: a nursing assistant's point of view. PMID- 6915479 TI - Towards a better understanding of the disabled. PMID- 6915480 TI - Joint-appointments: an agency experience : a response. PMID- 6915481 TI - Socialization of the nursing student in a professional nursing education programme. PMID- 6915482 TI - Accountability in nursing education. PMID- 6915483 TI - Joint-appointments: strengthening the clinical practice component in nursing education programmes. PMID- 6915484 TI - Separate funding: all in a day's work. PMID- 6915485 TI - Separate funding. 1. The case in favour. PMID- 6915486 TI - Teaching district nurses sociology. PMID- 6915487 TI - Communication skills: blockage and breakthrough. PMID- 6915488 TI - Separate funding. 2. The case against. PMID- 6915489 TI - Educational developments: the management objective in Joint Board curricula. PMID- 6915490 TI - A case for autonomy. PMID- 6915491 TI - Happy birth day? PMID- 6915492 TI - Time to overturn 'doctor's law'. PMID- 6915493 TI - Nurse, are you negligent? PMID- 6915495 TI - The discussion group in nursing education and practice. PMID- 6915494 TI - Nursing care study: coronary arteriography. PMID- 6915497 TI - Stress incontinence: the solution solidified. PMID- 6915496 TI - Pain and the nature of the placebo effect. PMID- 6915498 TI - Children in hospital--4. A link--person. PMID- 6915499 TI - The father's class. PMID- 6915503 TI - What is nursing? PMID- 6915501 TI - Systems of life No 84. Head & neck - 1. General examination. PMID- 6915502 TI - A community night nursing service in Essex. PMID- 6915505 TI - My quiet protest. PMID- 6915504 TI - Making the register effective. PMID- 6915500 TI - Hospital habits. PMID- 6915508 TI - Systemic changes in burn injury. PMID- 6915506 TI - Primary nursing: making a professional commitment. PMID- 6915507 TI - Primary nursing: steps towards the process. PMID- 6915509 TI - Facing the future. PMID- 6915510 TI - Behavioural objectives in nurse education. PMID- 6915511 TI - Evaluation of the Wessex experiment. PMID- 6915512 TI - Rheumatology: osteoarthritis and rheumatoid arthritis. PMID- 6915513 TI - Rheumatology: seronegative arthropathies. PMID- 6915514 TI - Disseminated connective tissue diseases. PMID- 6915515 TI - Gout. PMID- 6915516 TI - Rheumatology: this crippling disease. PMID- 6915517 TI - Meeting new needs. PMID- 6915518 TI - In the mind's eye. PMID- 6915519 TI - No more waiting! PMID- 6915520 TI - Child development. 3. Never a dull moment. PMID- 6915521 TI - Epidemiology. 6. The risk business. PMID- 6915522 TI - The 0-5 year old mentally handicapped child. 4. First catch your social worker. PMID- 6915523 TI - Health Education Council: on the front line. PMID- 6915524 TI - Nursing abroad: busman's holiday in Cuba. PMID- 6915525 TI - The nurse as the patient's advocate: pros and cons. PMID- 6915527 TI - Students' forum -- let's look at a problem: mental health. PMID- 6915526 TI - Decompression sickness: getting out of deep water. PMID- 6915530 TI - Constable, fireman, soldier--(and lastly) nurse. Interview by Andrew Brown. PMID- 6915528 TI - Mastectomy: personal experience-breast cancer. PMID- 6915529 TI - Nursing care study--senile dementia: Rosie... our Rosie. PMID- 6915531 TI - Education forum. 1. Communication. PMID- 6915532 TI - Communication skills: speak to me, nurse! PMID- 6915533 TI - Limitations of bureaucracy: a conflict of interests. PMID- 6915536 TI - Issues in nursing. 1. Management: the challenge that faces the profession. PMID- 6915535 TI - Arrival--a long route to nursing. PMID- 6915537 TI - Issues in nursing. 1. Management: shell-shocked managers await a new dawn. PMID- 6915534 TI - Nurses' pay: striking the right balance on nurses' pay. PMID- 6915539 TI - Smoking: why nurses smoke. PMID- 6915538 TI - Issues in nursing. 1. Management: graveyards are full of indispensable people. PMID- 6915540 TI - Smoking: slow motion suicide. PMID- 6915541 TI - Smoking and heart disease. PMID- 6915542 TI - Reorganisation: the Scottish connection. Interview by Catharine Sadler. PMID- 6915544 TI - Hormone replacement: the last flush of youth. PMID- 6915543 TI - Community nursing - Anytown anecdotes. 1. Jack Spratt and his wife. PMID- 6915545 TI - Blood groups. 1. First the bad news. PMID- 6915546 TI - Indoramin: under pressure. PMID- 6915548 TI - Neonatal nursing: baby love. PMID- 6915549 TI - School nursing. PMID- 6915547 TI - Nursing care study - mastectomy: the operation that every woman dreads. PMID- 6915550 TI - Developing role of school nursing: nursing in the schoolroom. PMID- 6915551 TI - Squint and amblyopia in children: correcting an unequal problem. PMID- 6915552 TI - 1982--the year of reckoning. PMID- 6915553 TI - For me it's the rest of my life. PMID- 6915555 TI - Too old for rabbits. PMID- 6915554 TI - Turbulent times. PMID- 6915556 TI - Bereavement and childbirth: look, listen and support. PMID- 6915557 TI - Sex roles and nursing: the men wear the trousers. PMID- 6915558 TI - Blood groups. 2. Making a match. PMID- 6915560 TI - Community--Dartmoor nurse: grockles, snow and steep hills. PMID- 6915562 TI - Alzheimer's disease: old before their time. PMID- 6915559 TI - Sleep paralysis: trapped in sleep. PMID- 6915561 TI - Zovirax: fighting a sore problem. PMID- 6915563 TI - Nursing care study--Crohn's disease: a vicious circle. PMID- 6915564 TI - Nursing care study--Parkinsonism in an elderly patient: in need of support. PMID- 6915565 TI - Nursing care study--liver failure: drank cup of tea unaided! PMID- 6915566 TI - School nursing: school nurse scholars. PMID- 6915568 TI - A critical analysis of the nursing profession and the role of unions. PMID- 6915567 TI - [Kallikrein-kinin system and the hemorrhagic syndrome in acute leukemia]. PMID- 6915569 TI - Nurses in struggle. PMID- 6915570 TI - Struggle of foreign nurses in the U.S. PMID- 6915571 TI - Job satisfaction and job performance of the Philippine Heart Center for Asia (PHCA) nursing personnel, 1980. PMID- 6915572 TI - The labor situation in nursing. PMID- 6915573 TI - Issues in nursing manpower development. PMID- 6915574 TI - Strategies for increasing membership in national nurses associations. PMID- 6915575 TI - The status of health workers. PMID- 6915576 TI - Establishing and achieving standards of nursing care: goal directed nursing care delivery model. PMID- 6915577 TI - Interviews: quality of nursing care and its determinants. PMID- 6915578 TI - Advocacy--a nursing challenge in the '80s. PMID- 6915579 TI - Creating critical consciousness in health: applications of Freire's philosophy and methods to the health care setting. PMID- 6915582 TI - Infectious diseases. PMID- 6915580 TI - Health care and human dignity. PMID- 6915581 TI - Maximizing the benefits of "watchers" in hospitals. PMID- 6915583 TI - Musculoskeletal infections in infants and children. PMID- 6915584 TI - Osteomyelitis: microbiologic, clinical, and therapeutic considerations. AB - A distinction between "acute" osteomyelitis and "chronic" osteomyelitis is difficult on both clinical and histopathologic grounds. The classification of osteomyelitis into three groups (hematogenous osteomyelitis, osteomyelitis secondary to a contiguous focus of infection, and osteomyelitis associated with vascular insufficiency) allows the physician to clearly distinguish among the types of infection on the bases of (1) the pathogenesis, (2) the bones involved, (3) the microorganisms responsible, and (4) the therapy. When antimicrobial agents are administered to a patient with any form of osteomyelitis, a bactericidal antibiotic should be employed, if possible. If feasible, a parenteral route of administration should be utilized, and therapy should be administered for a prolonged period of time. When more than one bactericidal antibiotic has been demonstrated to be effective against the isolated microorganisms, the least toxic agent should be selected. PMID- 6915585 TI - An approach to the child with pharyngitis. AB - In the child with pharyngitis, the physician's major task is to distinguish streptococcal from nonbacterial pharyngitis. Clinical and laboratory information is useful, but the diagnosis of streptococcal disease may be imprecise. Even the recovery of group A streptococcus from a throat culture must be interpreted with caution. Most physicians who treat a large number of children with pharyngitis will depend to a large extent on clinical judgment. When judgment is reinforced by a leukocyte count and differential and/or a throat culture, accuracy is enhanced considerably. Under the best of circumstances, some patients without streptococcal disease will be treated. Once the decision to treat is made, there is never a reason to use any drug other than penicillin for 10 days. In my experience, an injection of benzathine penicillin G, usually in combination with procaine penicillin G, is the safest, most effective, and most practical form of therapy, and compliance in 100 per cent of patients is ensured. PMID- 6915587 TI - Newer penicillin and cephalosporin antibiotics. PMID- 6915586 TI - Prevention of streptococcal neurosis. AB - Despite the decrease in the incidence and severity of rheumatic fever and rheumatic heart disease in the United States, overzealous emphasis on proper diagnosis and treatment of group A streptococcal pharyngitis in order to prevent these illnesses may often result in a frustrating, anxiety-provoking condition known as "streptococcal neurosis." Physicians, parents, and patients may all suffer from this condition, which often occurs even after all possible and appropriate treatment has been used to eradicate the group A streptococci. "Streptococcal neurosis" and the perplexing problem of treatment failure can be avoided or alleviated by utilizing knowledge of the interrelationship of the human host, the group A streptococcus, and nonsuppurative sequelae. PMID- 6915588 TI - Toxic shock syndrome. PMID- 6915590 TI - Atypical pneumonia syndrome. PMID- 6915589 TI - The ABCs of viral hepatitis: recent advances in laboratory differential diagnosis. PMID- 6915592 TI - Herpes zoster: a challenge in management. AB - Although herpes zoster is not a fatal disease, its legacy of postherpetic neuralgia gives rise to a great deal of misery and distress, especially in elderly patients. Furthermore, in the immunocompromised patient herpes zoster is an important complication. The management of the sequelae of herpes zoster continues to be extremely difficult. Although work on agents to control viral replication holds promise for the future, at present meticulous management of the pain and depression in the early phases and much patience and understanding in the later phases of the condition are necessary. PMID- 6915593 TI - Diagnosis, management, and prevention of infective endocarditis. AB - The epidemiologic, clinical, and microbiologic patterns of infective endocarditis have been undergoing constant change. Prompt diagnosis of infective endocarditis requires clinical suspicion in proper clinical settings and appropriate laboratory tests. Once the infecting organism is identified in blood cultures, the majority of patients with infective endocarditis can be cured by prolonged, intensive antimicrobial therapy. Surgical intervention may be needed in certain patients. Infective endocarditis may be prevented in some patients by the elimination of predisposing factors. Patients with underlying heart diseases should receive antimicrobial prophylaxis immediately before undergoing surgical procedures that are associated with significant risks of bacteremia. PMID- 6915591 TI - Infectious complications in diabetic patients. PMID- 6915594 TI - Nursing judgment in critical care: legalities. PMID- 6915595 TI - Supplemental staffing: nursing personnel pools. Care in point: McCutchon v. Mutual (354 Sw 2d 759 - LA.). PMID- 6915597 TI - Assaults in hospitals: nurses and patients. Case in point: May v. Triple C Convalescent Center (578 P. 2d 541 - WA). PMID- 6915596 TI - Legal case briefs for nurses. FL: M.D.-R.N. communications: doctor's information faulty. MI: nursing practice error: medical orders ignored. PMID- 6915598 TI - The binding of human lysosomal elastase to glomerular basement membrane. AB - The interaction of purified elastase with glomerular basement membrane and its antigens was studied. There appears to be at least two types of interaction. The first is a weak interaction and the enzyme can be removed simply by extended washing with neutral buffer. The second, stronger interaction is desorbed with high salt concentration at alkaline pH. The different interactions probably represent the binding of isoenzymes. Further experiments demonstrate that all isoenzymes degrade the membrane. Serum proteins prevent binding and inhibit the action of elastase on glomerular basement membrane. PMID- 6915601 TI - Infection consult. Tips and tactics to hold microbes at bay, for your patients' sake--and your own. PMID- 6915599 TI - Recovery of fungi from seeded sputum samples: effect of culture media and digestion procedures. PMID- 6915600 TI - Sex Q & A. Frank answers to your most delicate patient-counseling questions. PMID- 6915602 TI - A "minor" hand injury? Use these simple tests just to make sure. PMID- 6915604 TI - Toward impeccable IV technique: how to get the most out of Op-site... PMID- 6915603 TI - Can 'doctor's orders' include involuntary sterilization? PMID- 6915605 TI - The key to coping when everything happens at once. PMID- 6915606 TI - What does this nurse have in common with this patient? PMID- 6915608 TI - A 'magic' solution for all our staffing ills. PMID- 6915607 TI - New internal bile drain prolongs lives. PMID- 6915609 TI - We bit the bullet. PMID- 6915611 TI - Test yourself: dysrhythmia of the month club. What's behind all this variety in beats? PMID- 6915612 TI - Timmy a victim of his parents' loving care. PMID- 6915610 TI - The fine are of giving a physical: a systematic plan for assessing the head and face. PMID- 6915614 TI - Adrenal patient: proceed with caution. PMID- 6915616 TI - Advice of counsel: RN's legal advisory service: consent forms. PMID- 6915615 TI - Legally speaking. Infanticide: when doctor's orders read "murder". PMID- 6915617 TI - The BSN: an end to subservience. PMID- 6915618 TI - Leadership at work. The case of the "crazy" patient. PMID- 6915613 TI - Helping your patient through two painful tests. PMID- 6915619 TI - A problem patient: breaking the barrier. PMID- 6915621 TI - [Nutrition education--poor relative]. PMID- 6915620 TI - Post-basic education: another nursing crisis? PMID- 6915622 TI - [Death is no longer what it was]. PMID- 6915623 TI - [Toy Libraries for handicapped children]. PMID- 6915624 TI - [Bulwarks against the flu]. PMID- 6915626 TI - [The Pasteur Institute proposes a vaccine against hepatitis B]. PMID- 6915625 TI - [Survey of health facilities in Quebec]. PMID- 6915627 TI - [Methods of venous examination and therapeutic indications]. PMID- 6915628 TI - [Therapeutic principles for perforating planter disorders]. PMID- 6915630 TI - [Vitamin B1]. PMID- 6915629 TI - [Local care but also prevention and education]. PMID- 6915631 TI - [Nursing care of trophic foot disorders]. PMID- 6915632 TI - [Perforating planter disorder: the case of Mr. D]. PMID- 6915634 TI - [The nurse: from profession to education]. PMID- 6915635 TI - [Night-time health personnel]. PMID- 6915633 TI - [Foot ulcers of vascular etiology]. PMID- 6915636 TI - [Spinal injuries: diagnostic elements and therapeutic indications]. PMID- 6915637 TI - [Spinal injuries: severity of neurological risk]. PMID- 6915639 TI - [Recent spinal injuries: surgical technics]. PMID- 6915638 TI - [Anesthesia and resuscitation in spinal surgery]. PMID- 6915640 TI - [Anatomic review and stability factors of the spine]. PMID- 6915642 TI - [Rehabilitation of patients with spinal injuries]. PMID- 6915641 TI - [Technical role of the operating room nurse. Receiving the patient, instrumentation, osteosynthesis material, leaving the operating room]. PMID- 6915643 TI - [Geographic distribution of prematurity]. PMID- 6915645 TI - [Pregnancy and environment. Prevention of prematurity and its limitations]. PMID- 6915644 TI - [Pregnancy and environment. Influence of the socioeconomic level on prematurity]. PMID- 6915646 TI - [Disorders where the educational role of the nurse can be exercised]. PMID- 6915647 TI - [Vulvar pruritus]. PMID- 6915648 TI - [Leukorrhea in young girls]. PMID- 6915649 TI - [Regulation of patient visitors - a question of custom tailoring]. PMID- 6915650 TI - [Are we ruining our children's brains before their birth already?]. PMID- 6915651 TI - [A nursing care plan for rehabilitation following a cerebrovascular accident (CVA)]. PMID- 6915652 TI - [Systematic working in nursing care - the introduction of systematic working on the ward]. PMID- 6915653 TI - [Attention - a care aspect in the management of the mentally retarded client]. PMID- 6915654 TI - [The need for temporary nursing personnel and the role of the dispatching office]. PMID- 6915655 TI - [Sexual problems following surgery of the sexual organs]. PMID- 6915656 TI - [Systematic working in nursing care - introduction of systematic working on the ward. II]. PMID- 6915657 TI - [The Institute for Nursing Science has been established]. PMID- 6915658 TI - [Care of persons in acute crisis situations]. PMID- 6915659 TI - [Social and relational complications of being ill with C.A.R.A. (chronic aspecific respiratory affection)]. PMID- 6915661 TI - [Sexuality and intimacy in nursing homes and hospitals. Report of a 3-day course]. PMID- 6915660 TI - [This is how patients can feel. Nursing home]. PMID- 6915664 TI - How to operate an oxymonitor. PMID- 6915662 TI - Thoracoscopy in children. PMID- 6915663 TI - Operating room supervisor. PMID- 6915665 TI - Fear of sharp implements - or how I learned to appreciate nurses. PMID- 6915666 TI - Consciousness and health: what's it all about? PMID- 6915667 TI - Consciousness: the brain and self-regulation modalities. PMID- 6915668 TI - Care giving and natural systems theory. PMID- 6915669 TI - The child as a psychobiological being--implications for health care. PMID- 6915670 TI - Holistic dying: the role of the nurse clinician. PMID- 6915671 TI - High-level wellness and the nurse. PMID- 6915672 TI - Humaneness and health. PMID- 6915673 TI - Consciousness and caring: retrospective 2000. PMID- 6915675 TI - Surgical treatment of osteochondritis dissecans of the canine stifle. PMID- 6915676 TI - Persistent urinary tract infection and urolithiasis in a cat with a urachal diverticulum. PMID- 6915677 TI - Parvovirus: a few observations from a practitioner. PMID- 6915678 TI - Feline paraparesis. PMID- 6915674 TI - Vaccine causes an outbreak of bovine virus diarrhea (BVD). PMID- 6915679 TI - Surgical removal of a foreign body in a bastard turtle. PMID- 6915681 TI - Caudal epidural anesthesia in horses. PMID- 6915680 TI - Chronic suppurative infection of the left guttural pouch and eustachian tube in a horse. PMID- 6915683 TI - Surgical preconditioning of potentially high-producing dairy heifers. PMID- 6915682 TI - Keratoconjunctivitis in a llama. PMID- 6915684 TI - Pursuing a practical solution to bovine pinkeye. PMID- 6915685 TI - The economic effects of using thiabendazole to deworm a cow-calf herd. PMID- 6915686 TI - Comparison of intramuscular and oral modified-live virus TGE vaccines. PMID- 6915688 TI - Human values in nursing. PMID- 6915687 TI - [Comparative study of the lymphocyte protein-synthesizing activity of donors and chronic lympholeukemia patients]. AB - An assay of lymphocyte ribosomes in blood of donors and patients with chronic lymphocytic leukemia established the normal level of ribosomes in 11 cases and half that value in 6 cases of leukemia. The decreased level of ribosomes in cells was largely, registered at the terminal stage of the disease. The 14C-leucine uptake by leukemic lymphocytes was reduced 2-3-fold while the relative level of 14C-leucyl-tRNA in diseased and normal cells was identical. The rate of lymphocyte protein synthesis was lowered in a wide range (2-8-fold), in most of patients (7 out of 8). The rate of protein synthesis (radioactivity of acid insoluble fraction per mg of ribosomes) was half the normal value and constant in leukemic lymphocytes. An important role of ribosome level in protein biosynthesis regulation in the course of disease progression is suggested. PMID- 6915689 TI - The nursing shortage: ethical and professional issues of autonomy. PMID- 6915692 TI - In defense of diploma nurses. PMID- 6915691 TI - Bandaids or problem-solving? The choice is ours. PMID- 6915690 TI - Activity of selected enzymes in arterial wall and blood serum of rats with experimental atherosclerosis. AB - The activity of lysosomal hydrolases (hyaluronidase and beta-glucuronidase) as well as elastolytic activity in arterial wall and blood serum of rats with experimental atherosclerosis were determined. An increase of the enzyme activity was found in arterial wall, while in blood serum the rise of lysosomal hydrolase activity was accompanied by and unchanged level of elastolytic activity, as compared to control animals. The present studies show the participation of lysosomal enzymes and elastolytic activity in the development of atherosclerotic changes. PMID- 6915693 TI - Home care for the infant with congenital heart disease. PMID- 6915694 TI - The system and the patient. PMID- 6915695 TI - The water-load test. PMID- 6915697 TI - Dealing with feelings: preventing anger. PMID- 6915696 TI - Practical Piaget: helping children understand. PMID- 6915699 TI - Artificial speech devices. PMID- 6915698 TI - Rehabilitation for the patient with head and neck cancer. PMID- 6915700 TI - Drug data: drug-induced hepatotoxicity. PMID- 6915701 TI - Dilemmas in practice: no code? Slow code? Show Code? PMID- 6915702 TI - Nursing as an alternative to high-cost care. PMID- 6915703 TI - Op-Site for decubitus care. PMID- 6915704 TI - Gerontological nurse specialist: luxury of necessity? PMID- 6915706 TI - Radiation emergency. PMID- 6915705 TI - Hemodynamic monitoring: interpreting values. PMID- 6915707 TI - Iodide-an Rx for radiation accident. PMID- 6915708 TI - Antimicrobial resistance. PMID- 6915709 TI - Teaching parents about Reye's syndrome. PMID- 6915710 TI - Nurses on prime-time television. PMID- 6915711 TI - Repairing the Hickman catheter. PMID- 6915712 TI - Teaching the client about anticoagulants. PMID- 6915713 TI - Mohs' surgery for skin cancer. PMID- 6915714 TI - Family Hierarchies. PMID- 6915715 TI - Adopting an older child: the emotional process. The legal process. PMID- 6915716 TI - The percutaneous nephrostomy tube. PMID- 6915717 TI - Dealing with feelings. Managing angry feelings. PMID- 6915718 TI - Setting the stage for learning. PMID- 6915719 TI - Flawed perceptions about pain. PMID- 6915720 TI - New hepatitis B vaccine: a breakthrough in hepatitis prevention. PMID- 6915721 TI - Whose best interest? Parents vs. child rights. PMID- 6915722 TI - Noncontact detection of experimental amelanotic ocular melanoma with L-3-123I iodo-alpha-methyltyrosine. AB - An application of L-3-123I-iodo-alpha-methyltyrosine for the detection of ocular melanoma is presented. In rabbits with malignant Greene amelanotic melanoma transplanted to the anterior chamber of the eye, all tumors were detected in positive contrast using a gamma camera with a single pinhole collimator. The smallest tumor identified weighed 65 mg. Our data are compared with those obtained with 32PO4, 67Ga, 203Pb or labelled iodochloroquine. PMID- 6915723 TI - Vascular damage in the anterior uvea induced by intravitreal autogenous blood. AB - The effects of vitreous hemorrhages on anterior uveal vessels were studied. Albino rabbits were injected intravitreally with autogenous blood, plasma, RBCs, iron-dextrin, or Ringer's solution. The vascular permeability was assessed by fluorescein iris angiography, carbon labeling and penetration of peroxidase. Following one injection of blood, aqueous flare and fluorescein leakage from the iris were observed for 40 days. Intense vascular carbon labeling in iridial and ciliary processes was present for 1-40 days and weak-to-moderate labeling in the iris for 9-40 days. Repeated blood injections aggravated the vascular response, showing extravasation of peroxidase and carbon labeling of iridial vessels for 92 days. The most severe vascular damage ensued from iron-dextrin and RBCs. Plasma an Ringer's solution gave no reaction. The authors suggest that the iron containing degradation products of RBCs induce vascular damage in anterior uvea and disruption of blood-aqueous barriers. PMID- 6915725 TI - The amplitude of the c wave in the human ERG as a function of the luminous energy of the stimulus. AB - Variation of the stimulus intensity and duration over a wide range causes a change in amplitude of the c wave. If the energy of the applied stimulus is kept constant, however, stimuli of 0.05-4 s duration effected c waves that were nearly equal in amplitude. As patients consider shorter stimuli with higher intensities to be more comfortable in ERG recording, stimuli of a duration of 2-4 s seem most appropriate for clinical testing. PMID- 6915726 TI - Congenital hereditary retinoschisis: evolution at the initial stage. AB - Two male infants with congenital hereditary retinoschisis are presented. The disease was detected when they were 11 and 20 months old, respectively, and they were followed up during the subsequent months. Initially, they both revealed a tremendously elevated retinoschisis lesion in both equatorial an peripheral retina, which was associated with foveal retinoschisis. The peripheral ballooning retinoschisis regressed gradually in the following months, and a relatively flat retinoschisis was left. It was proposed that the early stage of the disease is characterized by a bullous retinoschisis followed by its spontaneous regression during the first several years of life. A survey of the literature favors our view. PMID- 6915727 TI - Inventory of registered nurses 1977-1978. PMID- 6915724 TI - Determination of infrared radiation levels for acute ocular cataractogenesis. AB - One hundred pigmented rabbit eyes and ten primate eyes were exposed to infrared (IR) radiation in the 715 to 1,400 nm wavelength range and to the full spectrum output from a 5,000 W Xenon high-pressure source. The ocular exposures were evaluated independently with a slitlamp by two researchers and classified for ocular damage. The primary ocular lesions resulting from exposure to IR radiation were corneal, iritic, and lenticular. Corneal damage varied from epithelial haze to epithelial erosion but no endothelial damage was found. The iris showed stromal haze and swelling. Lenticular changes showed small white dots that, occur at the level of the anterior cortex. All lens damage depended on iris involvement. Ocular damage was related to the rate of delivery of the IR radiation since the data show that as the irradiance level increases, the radiant exposure threshold decreases. Exposures for the full spectrum were found to be additive for irradiance levels at 4 W.cm-2 and above. The threshold radiant exposures for the full spectrum of 750 J.cm-2 for the cornea, 1,000 J.cm-2 for the iris, and 2,000 J.cm-2 for the lens were essentially identical to the IR exposure thresholds for the same irradiance levels. The primate threshold radiant exposure was a factor of six above the respective rabbit thresholds. PMID- 6915728 TI - The nursing practice act: suggested state legislation. PMID- 6915729 TI - Health care services for Native Americans. Report on a hearing; Albuquerque, New Mexico June 8, 1979. PMID- 6915730 TI - Standards of cardiovascular nursing practice. PMID- 6915731 TI - Conferees recommend policy for aged. PMID- 6915732 TI - 77-year-old nurse provides primary care for students. PMID- 6915733 TI - Poverty didn't stop Indian nurse leader. Interview by Mary Jane Dunlap. PMID- 6915734 TI - Nurse directs health services for state's prison population. PMID- 6915735 TI - Bylaws changes propose annual house. PMID- 6915736 TI - Who speaks for poor as states slice block grants? PMID- 6915738 TI - Research project produces 10 protocols on nursing care. PMID- 6915739 TI - Practice acts too broad, says report. PMID- 6915737 TI - As I see it: finding an alternative to collective bargaining. PMID- 6915740 TI - Education funds tied to IOM study. PMID- 6915742 TI - Federal report links shortage to wages. PMID- 6915741 TI - ANA works to win comparable pay, pension equity. PMID- 6915743 TI - Nurses haunted by memories of service in Vietnam. PMID- 6915744 TI - Cancer society sees reduction in smokers. PMID- 6915745 TI - Surgical separation of conjoined twins. PMID- 6915746 TI - Separating conjoined twins: a care plan. PMID- 6915747 TI - Conjoined twins: psychosocial aspects. PMID- 6915748 TI - OR instructor's notebook: a teaching plan for positioning. PMID- 6915749 TI - Body image after a stroke. PMID- 6915752 TI - Occupational health and safety. PMID- 6915750 TI - Social relations in stroke rehabilitation. PMID- 6915751 TI - Promoting research in rehabilitation nursing. PMID- 6915753 TI - The nurse and the law: drama in the theatre - Pt. II. PMID- 6915754 TI - Timolol maleate ophthalmic solution. PMID- 6915755 TI - Language disturbances due to brain lesions. PMID- 6915757 TI - How nursing and the community can benefit from nursing research. PMID- 6915758 TI - 'Futurizing' the curriculum - nursing education for the year 2000. PMID- 6915756 TI - Learning needs of registered nurses. PMID- 6915759 TI - The structured group of a psychiatric unit in a general hospital. PMID- 6915760 TI - Biomechanics - gait assessment in nurse education. PMID- 6915761 TI - Nurse education correspondence: a report. PMID- 6915762 TI - International code on marketing of breastmilk substitutes adopted by W.H.O. Assembly. PMID- 6915764 TI - Drugs in current use: pharmaquiz. PMID- 6915763 TI - The nurse and the law: consent. PMID- 6915765 TI - A group poisoning overflows an intensive care unit. PMID- 6915766 TI - A systems model of the nursing process. PMID- 6915768 TI - The application of power dynamics and relationships to terminal care. PMID- 6915769 TI - A multi-disciplinary approach to child abuse - the role of the nurse. PMID- 6915767 TI - A training in discipline and conformity? PMID- 6915770 TI - Eunice Paten Oration 1981: is your national nursing organization really necessary? PMID- 6915771 TI - The problem of obesity. PMID- 6915772 TI - Fire safety with gas sterilisation. PMID- 6915773 TI - Developing meaningfulness in medical communication. PMID- 6915774 TI - Book Obsolescence: an example from the literature of nursing. PMID- 6915776 TI - Our Karamajong children. PMID- 6915775 TI - On your metal? Amazing zinc! PMID- 6915777 TI - Certificate of accreditation. PMID- 6915778 TI - Inservice education for registered midwives in South Australia. PMID- 6915779 TI - A natural childbirth. PMID- 6915782 TI - Kinetics of the inhibition of leukocyte elastase by the bronchial inhibitor. AB - The rate constant for the association between human leukocyte elastase (EC 3.4.21.11) and human bronchial inhibitor has been determined by competition experiments with alpha 1-proteinase inhibitor. This constant (1.1.10(7) M(-1) . s(-1)) is 6-times lower than that for the association of leukocyte elastase and alpha 1-proteinase inhibitor. The latter inhibitor is able to dissociate the leukocyte elastase-bronchial inhibitor complex with a rate constant 1.3.10(-4) s 1. The equilibrium dissociation constant Ki of the complex is 1.2.10(-11) M. The physiopathological significance of these constants is discussed. PMID- 6915783 TI - Exotic diseases--communicable, dangerous, and, yes, possible! PMID- 6915780 TI - Protein turnover in pulmonary macrophages. Utilization of amino acids derived from protein degradation. AB - Conditions were defined under which rates of protein synthesis and degradation could be estimated in alveolar macrophages isolated from rabbits by pulmonary lavage and incubated in the presence of plasma concentrations of amino acids and 5.6 mM-glucose. Phenylalanine was validated as suitable precursor for use in these studies: it was not metabolized appreciably, except in the pathways of protein synthesis and degradation; it entered the cells rapidly; it maintained a stable intracellular concentration; and it was incorporated into protein at measurable rates. When extracellular phenylalanine was raised to a concentration sufficient to minimize dilution of the specific radioactivity of the precursor for protein synthesis with amino acid derived from protein degradation, the specific radioactivity of phenylalanyl-tRNA was only 60% of that of the extracellular amino acid. This relationship was unchanged in cells where proteolysis increased 2.5-fold after uptake and degradation of exogenous bovine serum albumin. In contrast, albumin prevented the decrease in phenylalanine incorporation observed in macrophages deprived of an exogenous source of amino acids. These observations suggested that macrophages preferentially re-utilized amino acids derived from the degradation of endogenous, but not from exogenous (albumin), protein. However, when the extracellular supply of amino acids was restricted, substrates derived from albumin catabolism could support the protein synthetic pathway. PMID- 6915784 TI - Brittle bones or osteogenesis imperfecta. PMID- 6915781 TI - Prolyl-tRNA-based rates of protein and collagen synthesis in human lung fibroblasts. AB - Knowledge of the dynamics of collagen turnover requires information regarding rates of synthesis of this group of connective-tissue proteins. The relationship of various amino acid pools to the tRNA precursor pool used for protein synthesis is known to vary between different cell types and tissues, even for essential amino acids. We studied extracellular, intracellular and tRNA-proline pools in cultured human lung IMR-90 fibroblasts to determine the relationship between them as candidate proline precursor pools for total protein and collagen synthesis. Time-course experiments showed that the three proline pools attained distinctly different steady-state specific radioactivities (extracellular greater than intracellular greater than tRNA) at the extracellular proline concentration of 0.2 mM. The kinetics of radioisotope incorporation into cell protein and collagenase-digestible protein indicated that the intracellular free proline pool could not be used reliably as a precursor for calculating synthetic rates. However, tRNA-proline behaved isotopically as if it were the precursor and provided synthesis rates 2-3-fold higher than those calculated by using either free proline pool. The incorporation of labelled lysine and leucine was constant over a wide range of extracellular proline concentrations. Fractional rates of protein synthesis based on tRNA-amino acid were the same with [3H]phenylalanine as with [3H]proline. The specific radioactivity of cell-associated hydroxyproline reached a steady-state value 8-10h after radioisotope administration which matched the mean tRNA-proline specific radioactivity, suggesting that tRNA proline is not isotopically compartmentalized. A model of cellular proline-pool relationship is presented and discussed. PMID- 6915786 TI - Nursing--vocation or profession? PMID- 6915785 TI - Head nurse and clinical instructor. A team approach helps both students and patients. PMID- 6915788 TI - Point of view: the entry to practice issue. We have seen the enemy. PMID- 6915787 TI - Planned parenting. PMID- 6915789 TI - Point of view: the entry into practice issue. The shouting starts. PMID- 6915790 TI - Dr. 99--an adult learning experience. PMID- 6915791 TI - Shopping for health? Maybe this storefront health information centre can help. PMID- 6915792 TI - Cancer, hypoalbuminemia, and nutrition. PMID- 6915793 TI - Granulocytopenia in the adult cancer patient. PMID- 6915795 TI - Cancer care at the volunteer level. PMID- 6915796 TI - Sexuality and gynecologic cancer. PMID- 6915794 TI - Stress and cancer: etiological significance and implications. PMID- 6915797 TI - Systematic misperception: oncology patients' self-reported affective states and their care-givers' perceptions. PMID- 6915799 TI - Programmed instruction: cancer care: leukemia. PMID- 6915798 TI - Cancer nursing and the law: valuing the missed opportunity for treatment. PMID- 6915800 TI - Pharmaceutics: antineoplastic agents as potential carcinogens: are nurses and pharmacists at risk? PMID- 6915802 TI - The course in advanced midwifery and neonatal care. Paper presented at the South African Multidisciplinary Medical Congress July 1981. PMID- 6915801 TI - Use of temporary epicardial electrodes for atrial pacing and monitoring. PMID- 6915803 TI - Educational objectives make or break the quality of patient care. Paper presented at a Symposium to celebrate the 25th anniversary of the degree course in nursing science at the University of Pretoria and in South Africa. PMID- 6915804 TI - [How do patients regard their nursing care? Excerpts from a presentation prepared for the level of M. Soc. Sc. (nursing) at the University of the Orange Free State]. PMID- 6915805 TI - The psychotherapeutic role of the nurse in a psychodynamic unit. PMID- 6915806 TI - [The nature and status of traditional, non-Western or basic medicine in South Africa]. PMID- 6915807 TI - Cardiac rehabilitation. Paper presented at the South African Multidisciplinary Medical Congress -- July 1981. PMID- 6915808 TI - A survey in Soweto (South Western Township) on the available health services. PMID- 6915809 TI - [The health education function of the nurse with reference to human genetics]. PMID- 6915810 TI - The working life of a group of nurses. PMID- 6915811 TI - Community development: health by the years 2000 -- health education and the community nurse. PMID- 6915812 TI - Community development and the community nurse. PMID- 6915813 TI - Community involvement--it can be done: a project with the aged in Brakpan. PMID- 6915814 TI - The role of the community nurse in family health care. PMID- 6915817 TI - Some aspects of traditional beliefs as they affect tuberculosis treatment. PMID- 6915815 TI - [The challenge connected to the delivery of primary health care in Article 30 areas]. PMID- 6915816 TI - Tuberculosis management -- some aspects of the role of the nurse manager. PMID- 6915818 TI - [The role of the community health nurse in mental health]. PMID- 6915819 TI - Primary health care. PMID- 6915820 TI - Occupational health in a hospital setting. PMID- 6915821 TI - The team concept in community health care. PMID- 6915822 TI - The community health nurse in school health services. PMID- 6915824 TI - Those Christmas slippers. PMID- 6915823 TI - [Major developments in health care delivery in the Republic of South Africa during the seventies]. PMID- 6915825 TI - Penetrating chest wounds. PMID- 6915827 TI - Infection control update! Salmonella. PMID- 6915828 TI - Grieving children. PMID- 6915826 TI - Cardiac rehabilitation update. PMID- 6915829 TI - Aspirin update! PMID- 6915830 TI - Abdominal trauma and hypovolemic shock. PMID- 6915831 TI - Tinnitus. PMID- 6915832 TI - Electrophysiological simulation of tinnitus. AB - The auditory brainstem response to clicks of 60 dB sensation level was recorded with superimposed pure tones at six frequencies and four sensation levels in an attempt to simulate the effects of tinnitus on the auditory brainstem response. Changes in responses were assessed by subtracting the auditory brainstem response obtained to the click-plus-tone from the auditory brainstem response obtained to the immediately preceding click alone. The dyssynchrony created by exogenously produced pure tones was considerable and probably reflected adaptation of individual single units; however, the auditory brainstem response to clicks alone changed markedly from the beginning to the end of the experiment and confounded a simple interpretation of the results. PMID- 6915833 TI - Epidemiology of tinnitus, Medical Research Council's Institute of Hearing Research. AB - The Institute of Hearing Research is now in the first of a three-year clinical characterization of hearing in the adult British population. One aim of this study is to obtain epidemiological data on the prevalence, and the handicapping effects and rehabilitational requirements for persons with hearing impairment, tinnitus, or both. The material presented here relates chiefly to the main pilot study. In Tier A, 6804 copies of a brief questionnaire were posted to random samples of people on the electoral rolls in Cardiff, Glasgow, Nottingham and Southampton. In Tier B, a stratified sample (n = 272) from the people who replied to the questionnaire was chosen for audiological and otological examination. The prevalence of tinnitus was 15.5-18.6% in the four cities, markedly less than the 39% found in the pre-pilot study, in which the wording of the questionnaire had not excluded spontaneous tinnitus of less tha five minutes' duration or temporary sound-induced tinnitus. In the four population sampled, tinnitus causing severe annoyance was reported by 0.4-2.8%, while a severe loss of the ability to lead a normal life was reported by 0.4-0.5%. The percentage reporting tinnitus increased significantly with age and with exposure to noise. PMID- 6915834 TI - Tinnitus in children with hearing loss. AB - The results are reported of a survey of tinnitus in deaf children in secondary school age. Of 158 children in five units for the partially hearing and two schools for the deaf. 78 were found to have tinnitus. The tinnitus was constant in two children and intermittent in the remaining 76. The frequency with which the tinnitus occurred, and its duration and loudness, are reported. Some children claimed that tinnitus reduced their hearing ability and speech discrimination. It some, tinnitus was associated with headache or vertigo. When it was unilateral, tinnitus was more commonly on the side of the better-hearing ear. A group of children was defined in whom the tinnitus had features that made it a particularly troublesome symptom. PMID- 6915835 TI - Tinnitus: surgical treatment. AB - Surgical treatment of tinnitus includes destructive procedures, neurectomies, stapedectomies and tympanosympathectomies. Translabyrinthine procedures for the removal of acoustic neuromas and sectioning of the eighth nerve to eliminate vertigo are analogous to cutting the eighth nerve as a surgical intervention for tinnitus. After surgical removal of acoustic tumours with excision of the auditory nerve in 414 patients, only 40% reported improvement in their tinnitus. Of 68 patients undergoing translabyrinthine eighth nerve section, 60 (80%) had tinnitus preoperatively. Improvement occurred in 45%, while 55% reported the condition to be the same or worse. In patients undergoing middle cranial fossa section of the vestibular nerve for vertigo or dizziness, most reported the tinnitus to be the same but a significant number felt that it was worse. Stapedectomy improves hearing in most patients but improves the symptom of tinnitus in only about half of the patients. Cochlear implant patients report an improvement in their tinnitus with use of the stimulator and implant. Implant procedures might therefore be used in patients who suffer from severe tinnitus. Surgical management of tinnitus, although successful in some cases, does not provide a valid and reliable mode of treatment for subjective tinnitus. PMID- 6915836 TI - Tinnitus masking:unresolved problems. AB - With care to provide properly chosen masking sounds, masking can help in 60-80% of clinically significant tinnitus cases. There is no universal masker; instead, an individual evaluation of each patient's tinnitus must be performed in order to match the masking sounds to the patient's audiogram and the spectral characteristics of the tinnitus. Successful long-term masking can usually be achieved in patients for whom (1) hearing impairment is not excessive. (2) the tinnitus frequency, FT, can be reliably located, and (3) the tinnitus can be completely masked by a band of noise at or near FT at a low sensation level. Such patients often experience residual inhibition (temporary suppression of tinnitus upon cessation of masking) which may accumulate with sustained use of masking, in some cases becoming permanent. Long-term masking is difficult or impossible for patients whose hearing is so impaired they cannot hear the masker, or those for whom the masking sounds must be presented at unacceptably loud levels to obtain adequate coverage of the tinnitus. There is a great need for additional work to determine what factors influence the effectiveness of masking, in order to improve our ability to provide appropriate masking stimuli even for the difficult cases. PMID- 6915837 TI - Measurement of tinnitus in humans. AB - Little quantitative measurement of tinnitus was possible before the development of the electric audiometer. Since then many ingenious attempts have been made to simulate the phenomenon. Frequency and masking measurements were described first in 1931 by E. M. Josephson and also by R. L. Wegel, and techniques involving loudness balance, free-field matching and taped sound effects have also been used. More accurate measurement of frequency content can be made by means of music synthesizer. A tinnitus measurement protocol should include assessment of: (1) frequency content; (2) loudness; (3) masking characteristics; and (4) objective measurements. Loudness measurements relate to the annoyance caused by the symptom, which depends, too, on the patient's personality and disposition. Masking characteristics also relate to the loudness of tinnitus and give additional guidance about the suitability of making therapy. They are repeatable and easy to perform. Objective measurements, whether performed with a stethoscope or intrameatal microphone, may reveal vascular bruits or cochlear emissions. We must wait to see how representative are the newer objective measurements of the subjective complaint. PMID- 6915838 TI - Classification of tinnitus. AB - Classification in general serves a number of purposes. In relation to tinnitus there are particular problems because the cause in only rarely known and the mechanism is not known at all. This means that firm classifications tend to be misleading and serve little purpose other than to delude the doctor and the patient. The aim in this paper therefore is to examine the various ways in which information (whether scientific or clinical) about tinnitus can be organized so as to help diagnosis, management or research towards recognition of the fundamental abnormalities. Attempts at classification based on the site of the lesion and on speculation about its cause are described. Classification is analysed according to (1) patients' own reports, (2) doctors' clinical observations, (3) various techniques of measurement, (4) associated phenomena and (5) results of treatment. From these various aspects a pattern emerges which, though incomplete, at least exposes rather than obscures the gaps in our knowledge. PMID- 6915840 TI - Appraisal of the diabetic patient. PMID- 6915839 TI - The microcomputer: an extension of the diabetes educator. PMID- 6915841 TI - The fructose story. PMID- 6915842 TI - An examination of diabetes educational assessment forms. PMID- 6915843 TI - Simplifying diet plans for the adult limited learner. PMID- 6915844 TI - Information for ileostomy patients. PMID- 6915845 TI - Wound healing: a review. II. Environmental factors affecting wound healing. PMID- 6915847 TI - Cases, problems, and solutions: creative ostomy care. PMID- 6915846 TI - Teaching the preschooler with two ostomies. PMID- 6915848 TI - Bioethics of cancer nursing. PMID- 6915849 TI - The psychological impact of a stoma. PMID- 6915850 TI - Urinary findings in 20 asymptomatic patients with an ileal conduit. PMID- 6915851 TI - Wound healing: a review. III. Nutritional factors affecting wound healing. PMID- 6915852 TI - Interview with two recipients of penile implants. PMID- 6915853 TI - Cases, problems, and solutions. PMID- 6915855 TI - [Effect of salivary kallikrein on mineral metabolism in tissues of the dento mandibular system in rats]. PMID- 6915854 TI - Comparison of the hydrolysis patterns of several tRNAs by cobra venom ribonuclease in different steps of the aminoacylation reaction. AB - The hydrolysis of several tRNAs by an endonuclease extracted from the venom of Naja oxiana and specific for double-stranded, or at least highly ordered, regions has been studied under various experimental conditions. It is shown that the hydrolysis patterns of yeast tRNAPhe, tRNAVal and tRNAAsp in the isolated state are similar, most of the cuts occurring in the anticodon and acceptor stems. Ionic conditions are able to modify the hydrolysis pattern. The origin of these modifications is discussed. The protection against ribonuclease action, afforded to tRNAPhe, tRNAVal and tRNAAsp by the cognate aminoacyl-tRNA synthetase, is analyzed. It is shown that in all cases the anticodon stem is protected. The 3' terminal region does not seem to be tightly engaged in the complex with the aminoacyl-tRNA synthetase. These results are discussed in the light of information on contact areas previously obtained by ultraviolet cross-linking techniques. The effects of the small ligands (ATP and amino acid) on the protection afforded to the tRNA by the cognate synthetase, have been studied. In the valine and aspartic acid systems, ATP induced a modification of the tRNA enzyme complex leading to differences in the hydrolysis pattern of the 3' accepting region. The effects of aminoacylation on the cleavage of tRNAPhe, tRNAVal and tRNAAsp were also studied. Whereas no modification of the cleavage map was observed in the aspartic system, aminoacylation resulted in slight but significant modifications of the hydrolysis pattern for tRNAPhe and tRNaVal in the 3'-terminal region. PMID- 6915856 TI - [The value of different investigations in the preoperative diagnosis of ectopic pregnancy (author's transl)]. PMID- 6915857 TI - [The prevention and treatment of recurrent urinary stress incontinence with the suspension according to Zoedler (author's transl)]. AB - 115 patients with severe urinary stress incontinence were operated according to the method of Zoedler with a nylon ribbon (31 cases) and a lyodura ribbon (84 cases). There were 56 primary operations and 59 operations for recurrence. In 13 patients the operation was combined with a fixation to the promentory according to Kuestner-Wagner. Continence was obtained in 90.3% of the cases at the end of one year in 84.2% of the cases at the end of three years and in 83% of the cases at the end of five years. The recurrence rate for the operations for recurrent stress incontinence was 20.6% the recurrence rate in the primary operations was 9.1%. The complications were described. The lyodura sling procedure is today primarily practiced as an operation for recurrent stress incontinence. PMID- 6915858 TI - [The importance of lymphadenectomy for therapie of ovarian carcinoma (author's transl)]. PMID- 6915859 TI - [Long term experience with the IUD copper-T-200 (author's transl)]. AB - During a period of seven years pregnancy-, expulsion- and extraction-rates of the copper-T-200 were determined for two different groups of patients in a university hospital. The first group were patients of the ambulatory care service representing an heterogenous composition. The other group were patients from a private practice representing a more homogenous population. In the first group insertions and controls were done by different physicians at various stages of their training, in the second group they were performed by an experienced clinician. In the first group there were 1397 primary IUD-insertions and 22,203 months of use, in the second group the corresponding data were 272 primary insertions an 5127 months of use. The pregnancy rates calculated according to the Pearl-index were 1.0 and 0.24, respectively. The expulsion rates were calculated as 0.8 and 0.2, respectively. The extraction rates because of unwanted side effects were 4.4 in the first and 1.6 in the second group of patients. There seems to be an advantage in having the care of the IUD-patient being taken by an experienced physician, especially regarding the extraction rates because of unwanted side effects. PMID- 6915861 TI - [Investigation of the effect of intrapartal care for childbirth in relation to childbirth preparation (author's transl)]. PMID- 6915860 TI - [The induction of abortion in the second trimester by combined administration of minprostin and sulproston, compared with the use of sulproston alone (author's transl)]. AB - Sulproston was used to terminate 125 pregnancies from 13 to 41 weeks duration, between 1.1.1979 and 31.12.1980. The indications for termination of pregnancy included medical problems, genetic disorders and neural tube defects. Sulproston alone was used in 30 cases. In the remaining 95 cases the cervix uteri was treated with Minprostin F2a before Sulproston application. The failure rate was 20% when Sulproston alone was used at varying dosage. There were no failures using the combination therapy. Combined therapy reduced the time necessary for abortion by an average of four hours, the period of painful contractions was reduced, and less Sulproston was needed. The incidence of side effects was comparable in the two groups. There were no complications from the intracervical application of Minprostin F2a. PMID- 6915862 TI - [Measurement of motor nerve conduction for precise maturity determination in low birth weight newborn infants]. AB - Between 1.10.1979 and 31.1.1981, maturity estimation tests were conducted on 379 eutrophic and 78 hypotrophic neonates at the Department of Obstetrics in Berlin Neukolln by means of motor nerve conduction velocity (NCV) combined with the FARR system. In both eutrophic and hypotrophic infants the median of the nerve conduction velocity rises almost in a straight line from 16.5 m/sec in the 34th week of gestation to 25.7 m/sec in the 41st week. The significance calculation of the nerve conduction velocity of both groups showed no variation (p less than 0,01). On the other hand the maturity estimation made with the FARR system deviated strongly in a false positive direction up to the 38th week of gestation. The measurement of the motor nerve conduction velocity of the ulnar nerve has proved to be a simple and very precise estimation of the postpartum gestational age which makes it possible to distinguish with certainty between premature eutrophic infants and hypotrophic infants of low birthweight. PMID- 6915863 TI - [Experience with EK-birthing chair (author's transl)]. AB - A birthing chair with a rigid plastic seat was tested for usefulness and safety. The birthing chair was evaluated positively by the delivering patients. The obstetric team was convinced of the advantages of the sitting position for delivery at the end of the evaluation. Minor disadvantages such as increased soiling of the chair were accepted for the advantages. The tested birthing chair impedes operative deliveries from the perineal floor. These may become necessary unexpectedly during the second stage of labor. Under these circumstances the patient must be transferred to a conventional delivery table. This is psychologically and from a standpoint of the work load very disadvantageous. Therefore the EK-birthing chair is of limited usefulness in routine obstetrics. An ideal birthing chair in our opinion is a delivery bed which can be changed into a sitting position and into all intermediate positions between sitting and recumbent. PMID- 6915864 TI - [Medical record--memory aid or incriminatory evidence?]. PMID- 6915866 TI - Legislative commentary: uniform determination of death act. PMID- 6915865 TI - [Sense and nonsense in the influence of psychology on obstetrics]. PMID- 6915868 TI - Future planning: occupation and career choices. PMID- 6915869 TI - Let's care about abused children. PMID- 6915870 TI - Strike?!?! What am I going to do? PMID- 6915867 TI - Breakthrough to nursing. Caring through understanding: Part I. Native Americans. PMID- 6915871 TI - It's up to you: the future of nursing research. PMID- 6915872 TI - Every good business invests in research: shouldn't nursing also? PMID- 6915873 TI - Profile of a nurse researcher. Interview by BJ Nerone. PMID- 6915874 TI - The house that love built: Ronald McDonald houses offer support for families, volunteer opportunities. PMID- 6915875 TI - Rights and responsibilities of students and faculty. PMID- 6915876 TI - Suggestions for change in nursing education: a student's view. PMID- 6915877 TI - [Schools against poor diet]. PMID- 6915878 TI - [Phospho-calcium metabolism]. PMID- 6915880 TI - [Pathology particular to health personnel]. PMID- 6915881 TI - [Renal echotomography]. PMID- 6915879 TI - [Psychiatric nursing: the adult psychiatric sector]. PMID- 6915882 TI - [Vacation in China]. PMID- 6915883 TI - [Receiving emergencies]. PMID- 6915884 TI - [Psychiatric nursing: law of 30 June 1838. 1]. PMID- 6915885 TI - [Nurses faced with the problems of prostitution. Prostitution and health: dispensaries]. PMID- 6915886 TI - [Continuous ambulatory peritoneal dialysis: ideal treatment for certain children]. PMID- 6915888 TI - [Subcutaneous heparinotherapy]. PMID- 6915887 TI - [A systematic approach to the individualization of instruction]. PMID- 6915890 TI - [Living with old age]. PMID- 6915889 TI - [Care-givers and children in psychiatry: interactions between personnel and children and adolescents in a mental health center]. PMID- 6915892 TI - [Exotic diseases: dangerous and transmissible]. PMID- 6915891 TI - [Foreseeing the future]. PMID- 6915893 TI - [For elderly people loving life? Needs of people in good health]. PMID- 6915894 TI - [The aging of hearing]. PMID- 6915895 TI - [The reverse of nurseries... pleading for the elderly]. PMID- 6915896 TI - [Respect for the elderly]. PMID- 6915897 TI - [Point blank: patient transfer--experienced reality]. PMID- 6915898 TI - Excessive levels of gram-negative bacteria in hemodialysis machines. PMID- 6915899 TI - Iodine--champagne in a tin cup. PMID- 6915900 TI - Techniques known to prevent post-operative wound infection. AB - The most important factors in controlling postsurgical sepsis are appropriate surgical judgment and technique. Efficacious prophylactic antibiotics, when indicated, also significantly reduce the postoperative infection rate. Among the other techniques often heralded as important adjunctive measures, only duration of preoperative hospitalization, preoperative bathing, use of electrocautery, preoperative hair removal, use of prophylactic drains, and duration of operation are of proven significance. PMID- 6915901 TI - Perioperative prophylactic use of antibiotics in surgery: principles and practice. AB - Prophylactic use of antimicrobics represents about 30% of total hospital use of these agents. Previous studies in animal models have suggested that timing of such prophylaxis is crucial, to the extent of the existence of a "critical period" for effective administration. This phenomenon has further been shown to exist in man, in numerous double-blind, controlled clinical trials in various types of surgical wounds. On these bases, we introduced new prophylactic protocols in a university hospital, specifically directed at reducing infection in high-risk procedures. Surveillance was conducted by infection control nurses, and one antibiotic-day was the comparative unit. Infection rates were markedly diminished under these new protocols. Total usage of antimicrobial drugs also decreased by 38% over previous rates. The rationale for limiting prophylaxis to a circumscribed period was clearly demonstrated, although the exact mechanisms responsible for this effect are, as yet, unclear. PMID- 6915902 TI - Effective and creative surveillance and reporting of surgical wound infections. AB - Surgical wound infections offer a major challenge to hospital infection control programs. Surgical procedures and host factors are independent variables which markedly influence the risk of infection. Frequently used categories of surgical procedures (clean, contaminated, and infected) are inadequate to identify the special risks and problems of individual procedures. In 1976, in conjunction with the practicing surgeons of a large, referral hospital, the Infections Control Committee instituted surveillance of selected clean surgical procedures and deep versus-superficial wound infections. Major problems associated with the cleaning of sternal saws and the timing of the administration of prophylactic antibiotics have been detected by these methods. Conventional surveillance undoubtedly would have overlooked these problems. Effective surveillance and control of surgical wound infections requires a willingness to modify surveillance activities to meet the local needs, and a determination to include the operating surgeons in the planning of surveillance activities. PMID- 6915904 TI - Coagulase-positive staphylococci. AB - S. aureus is a frequent and constant colonizer of the skin and mucosal surfaces of humans. It has the capability of producing a large number of enzymes that contribute to its pathogenic potential. S. aureus is a common cause of nosocomial infections, particularly wound- and IV-catheter-associated infections. Lysogenization of these organisms appears to contribute to a number of properties, the most important of which is the resistance to antimicrobials. Such resistance is an important problem--both clinically and in the microbiology laboratory--where the not infrequent inability to identify such resistant strains may contribute to morbidity and mortality of staphylococcal disease. PMID- 6915903 TI - Update: hepatitis B vaccine "the FDA approved the new vaccine on November 17, 1981". PMID- 6915905 TI - Data analysis vs. data examination. PMID- 6915906 TI - Evaluation of student nurse clinical performance--a continuing problem. PMID- 6915907 TI - Pain medication for the terminally ill. PMID- 6915908 TI - Nurse practitioners in primary health care: the Jamaican experience. Part I. PMID- 6915909 TI - Responsibility in nursing. PMID- 6915910 TI - Childhood illness and community care. PMID- 6915911 TI - Children with epilepsy: the health visitor's role. PMID- 6915912 TI - Know your organizations: the Cystic Fibrosis Research Trust. PMID- 6915913 TI - Know your organizations: the Psoriasis Association. PMID- 6915914 TI - Muscular dystrophy. PMID- 6915916 TI - Coeliac disease in children and adults. PMID- 6915915 TI - Know your organizations: the National Society for Phenylketonuria and Allied Disorders. PMID- 6915917 TI - Effects of alternative techniques of low-dose heparin administration on hematoma formation. PMID- 6915918 TI - Measuring tracheal tube cuff pressures--tool and technique. PMID- 6915919 TI - Type A behavior: Observations on the past decade. PMID- 6915920 TI - Quinidine in perspective: "The rise and fall of quinidine". PMID- 6915921 TI - The educational needs of coronary care nurses ten years later. PMID- 6915922 TI - Stress and intensive care nursing: A ten-year reappraisal. PMID- 6915924 TI - Arrhythmias in coronary care: a renewed plea. PMID- 6915923 TI - Respiratory failure and the heart--revisited, 1982. PMID- 6915925 TI - Emergency operation for complications of myocardial infarction. PMID- 6915926 TI - Psychologic stress in intensive care unit and non-intensive care unit nursing: A review of the past decade. PMID- 6915927 TI - Prevention of death and morbidity associated with hypertension in the community: a ten-year appraisal, 1972 to 1982. PMID- 6915928 TI - Respiratory care today-and tomorrow. PMID- 6915931 TI - Pediatric electrocardiography overview. PMID- 6915930 TI - The quality of nursing journals as rated by deans of nursing schools. PMID- 6915929 TI - Contributors to coronary risk: ten years later. PMID- 6915932 TI - Prognosis after myocardial infarction-ten years of change. PMID- 6915933 TI - The diagnosis of myocardial infarction in patients with permanent pacemakers. Part II. PMID- 6915934 TI - Structure of a spinach chloroplast threonine tRNA gene. AB - The gene for spinach chloroplast tRNAThr3 has been sequenced and is co-linear with the tRNA, does not contain an intervening sequence, and does not code for the 3'-terminal CCA, which is added post-transcriptionally. This gene shares features with prokaryotic, eukaryotic, and mitochondrial tRNA genes. The opposite strand of the tRNA gene contains a proper ribosome binding site, homology to a classical bacterial promoter, and could potentially code for a small peptide. PMID- 6915935 TI - Protein synthesis in rabbit reticulocytes. A study of peptide chain initiation using native and beta-subunit-depleted eukaryotic initiation factor 2. PMID- 6915937 TI - The cleavage and formation of activated human Hageman factor by autodigestion and by kallikrein. AB - We have compared the cleavage of purified human Hageman factor (HF) by an activated form of human Hageman factor (HFa) (autodigestion) and by kallikrein. In each case, an initial cleavage is seen which produces HFa with Mr = 80,000 consisting of a heavy chain of Mr = 52,000 disulfide-linked to a light chain of Mr = 28,000. As autodigestion proceeds, HFa is shown to be further digested to yield a major active product at a molecular weight of 40,000 as well as Hageman factor fragment (HFf), which appear as two closely related molecular species of Mr = 28,000 and 30,000. A minor active product of Mr = 70,000 is also seen. Upon reduction of each of the active forms, a chain with Mr = 28,000 is released which contains the active site. HF digestion by kallikrein results in rapid formation of HFa, followed by HFa digestion to HFf and degradation of the heavy chain region to an inactive fragment at 40,000 daltons, which is then degraded to an end product of Mr = 36,000. Production of the active species with Mr = 40,000 and 70,000 is greatly diminished when kallikrein is the HF activator, and these active forms are shown to be formed primarily by autodigestion. The time course of HFa and HFf formation indicates that the rate of activation of Hageman factor by kallikrein is much faster than the rate of autoactivation; the addition of high molecular weight kininogen increases the rate of HFa and HFf formation as well as the extent of HG digestion. These data indicate that HFa is the active intermediate from which other active species are derived. The patterns of HF and HFa digestion by HFa and kallikrein are distinct; a model for HF digestion is presented. PMID- 6915936 TI - Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle? PMID- 6915938 TI - Location of the intermediate and high affinity omega-aminocarboxylic acid-binding sites in human plasminogen. PMID- 6915941 TI - The clinical nursing specialist and the nurse practitioner. PMID- 6915942 TI - Breast engorgement in non-nursing mothers following administration of estrogen containing lactation suppressant medication. PMID- 6915944 TI - Nurse-midwifery practice in high-volume tertiary care settings. PMID- 6915939 TI - Increased enzymatic activity of the alternative pathway convertase when bound to the erythrocytes of paroxysmal nocturnal hemoglobinuria. AB - To investigate the greater fixation of C3 to the erythrocytes of patients with paroxysmal nocturnal hemoglobinuria (PNH) upon activation of complement, we have examined the formation and the reaction of the C3 nephritic factor-stabilized alternative pathway convertase made with purified components on normal and PNH erythrocytes. Each convertase complex converts four to five times more fluid phase C3 to C3b when affixed to a PNH cell than when affixed to a normal cell. The greater activity of the convertase on PNH cells is not due to differences in the intrinsic or extrinsic stability of the convertase complex. The excessive binding of C3 to PNH cell si due to this increased conversion of fluid-phase C3, because the efficiency of binding of nascent C3b was identical for the two cell types. This is the first instance in which the enzyme activity of a complement complex has been shown to be increased by being affixed to an abnormal surface. PMID- 6915943 TI - The frequency of stress incontinence in women before and after the implementation of an exercise program. PMID- 6915940 TI - Elastase of U-937 monocytelike cells. Comparisons with elastases derived from human monocytes and neutrophils and murine macrophagelike cells. AB - As an approach to facilitating the understanding of proteinases associated with monocytes we have studied U-937 monocytelike cells. Elastase activity was identified in U-937 cell extracts and compared to monocyte elastase activity, neutrophil elastase, and the elastase activity from a continuous line of murine macrophagelike cells (P388D1). Serine proteinase activity which solubilized (14)C labeled elastin accounted for >90% of the neutral proteinase activity of both U 937 cells and monocyte extracts. U-937 cell and monocyte elastase activities were similar catalytically, resembling neutrophil elastase. U-937 cells and monocytes showed other similarities: (a) both had activities reacting with [(3)H]diisopropylfluorophosphate that migrated in sodium dodecyl sulfate (SDS) polyacrylamide gels at approximately 30,000 and 60,000 daltons and (b) both contained material that cross-reacted with antiserum raised to neutrophil elastase. Preliminary characterization of U-937 cell elastase activity by affinity chromatography and ion-exchange chromatography suggested the presence of at least two distinct elastases. Minimal elastase activity was found in U-937 cell-conditioned medium, indicating that the activity is not spontaneously released by the cells. In contrast to the elastase activity associated with U-937 cells and monocytes, the elastase activity associated with P388D1 cells was a metalloproteinase and was found principally in the culture medium. These results indicate (a) U-937 cells will be useful for further investigation of proteinases associated with normal monocytes; (b) monocytes and U-937 cells contain material with catalytic and immunologic similarities to neutrophil elastase; (c) monocyte elastase activity differs from elastase activity secreted by murine macrophages and murine macrophagelike cells of the P388D1 line. PMID- 6915945 TI - Conductivity and its relationship to dialysate composition. PMID- 6915946 TI - Experience with subclavian catheterization for hemodialysis. PMID- 6915947 TI - Toward personalized education for adult ESRD patients. PMID- 6915948 TI - Law, employment, and the ESRD patient. PMID- 6915949 TI - Problems and solutions for home dialysis in the 1980's. PMID- 6915950 TI - Nursing care of the aged: an overview of education, research and practice in England and Wales. PMID- 6915951 TI - Nursing care of the aged in Mexico. PMID- 6915952 TI - Nursing care of the aged in the Netherlands. PMID- 6915954 TI - Alcohol abuse in the elderly. PMID- 6915955 TI - Regression: a defense mechanism for the dying older adult. PMID- 6915953 TI - Nursing care of the elderly in Scotland. PMID- 6915956 TI - Personal perspectives on aging and nursing. PMID- 6915958 TI - How does the 12-hour shift affect patient care? PMID- 6915959 TI - Leadership for expanding nursing influence on health policy. PMID- 6915960 TI - How to run a meeting. PMID- 6915957 TI - Antibody restores human alternative complement pathway activation by mouse erythrocytes rendered functionally deficient by pretreatment with pronase. AB - Activation of the human alternative pathway of complement (C) by surfaces requires the initial deposition of C3b by fluid-phase C3 convertase and sustained C3 cleavage by C3 convertases fixed to the surface. Nonactivating particles have previously been characterized by an inability to sustain the function of C3 convertases on their surfaces because these sites were susceptible to the regulatory action of the control proteins. Pronase converts the mouse erythrocyte (E) from an activator to a nonactivator by markedly decreasing the ability of the cell to affix C3b generated by a fluid-phase C3 convertase; this conversion is unrelated to the action of the control proteins on bound C3b. The capacity of antibody and its F(ab')2 or Fab' fragments to restore the alternative pathway activating function of pronase-treated mouse E indicates that the contribution of antibody is mediated by its combining site without a requirement for bridging or for the Fc portion. The fab'-dependent activation of the alternative pathway of C relates to the deposition of C3b on the particle surface, which is a first and continuing step in alternative pathway activation. The antibody effect is not directed to the action of the regulatory proteins. Thus, particle-dependent activation of the alternative C pathway has been shown for the first time to be abolished and restored by cell surface-directed mechanisms that function independently of the regulatory proteins. PMID- 6915961 TI - The research question. AB - When the seeds of a research idea begin to germinate, researchers use a systematic and rational process to develop the idea into a refined research question and then determine the appropriate study design. Knowledge of the characteristics of a good research question helps researchers formulate a valid statement of the problem under study and then narrow it to a researchable question. A simple visual mechanism simplifies conceptualization of the study area. Finally, a building-block approach helps researchers organize knowledge from the existing research literature, so as to refine the question and select the appropriate level of testing. At the end of this phase, researchers have refined the initial research idea to an explicit statement, ready for testing. PMID- 6915962 TI - Hospital practice for certified nurse-midwives--privilege or right? PMID- 6915963 TI - A new approach to prenatal care records: client participation in identifying needs, planning care, and recording data. PMID- 6915964 TI - Nurse midwives and physicians: a team approach to obstetrical care in a perinatal center. PMID- 6915965 TI - Today's midwife tomorrow. PMID- 6915966 TI - The birth controllers: limitations on out-of-hospital births. PMID- 6915967 TI - Comparison of hospital charges generated by certified nurse-midwives' and physicians' clients. PMID- 6915968 TI - Serum hemolytic factor D values in children with steroid-responsive idiopathic nephrotic syndrome. AB - Serum hemolytic factor D activity, an important component of the ACP, was measured in patients with SR-INS. The mean serum factor D hemolytic activity of patients with SR-INS in relapse was significantly reduced compared to the mean of the control group. Twenty-one of 27 SR-INS patients in relapse (78%) had reduced serum factor D activity. In contrast, the mean serum factor D hemolytic activity of SR-INS patients in remission was not significantly different from that in the control group. Factor D hemolytic activity was also reduced in other types of renal disease with the nephrotic syndrome. Serum factor D values were highly correlated with the serum albumin concentration. Although hemolytic factor D activity could not be detected in the urine, the low molecular weight and the significant correlation with serum albumin concentration suggest that urinary loss is responsible for the low serum levels of factor D. Deficient serum values of factor D may contribute to the increased susceptibility of SR-INS patients in relapse to bacterial infections with organisms which activate the ACP. PMID- 6915969 TI - Medication counseling: the right of all patients. PMID- 6915970 TI - Nonsteroidal anti-inflammatory agents - Part III. PMID- 6915971 TI - The patient in chronic pain: a challenge to nursing care. PMID- 6915973 TI - Menstrual pain: new remedies for a very real disorder. PMID- 6915972 TI - Please chart endurance: one LPN's personal experience with chronic pain. PMID- 6915974 TI - Commit yourself to caring. PMID- 6915975 TI - The LP/VN's role in medication counseling. PMID- 6915977 TI - The nurse's role in respiratory care. PMID- 6915978 TI - Adult respiratory distress syndrome: a challenge to nursing care. PMID- 6915979 TI - Catheter care and UTI: a photo essay on good technique. PMID- 6915976 TI - Nonsteroidal anti-inflammatory agents, Part IV - A new analgesic: zomepirac. PMID- 6915981 TI - Legal liability and the LP/VN. PMID- 6915980 TI - Team leadership and management skills: a new area for today's LP/VNs. PMID- 6915982 TI - Pancreatic elastase activation as a possible indicator of the relative hazard of different cigarettes. AB - Levels of elastase activity in homogenates of pancreas from beagle dogs exposed to cigarette smoke on a daily basis for 600 d were previously reported. Elastase activity in pancreatic homogenates from animals exposed to smoke from high nicotine cigarettes was significantly greater than in sham-exposed controls or in animals smoking low-nicotine cigarettes. In the study described here, dogs were exposed on an acute basis to smoke from high-nicotine and from nicotine-free cigarettes. Anesthetized animals were prepared by laparotomy, duodenotomy, and pancreatic duct cannulation. Pancreatic fluid was collected and preexposure elastase levels were determined. Samples were then taken during exposure to smoke from cigarettes of both types. There was no measurable elastase activity in the baseline samples. Similarly, no activity was found in fluids collected before and during exposure to smoke from nicotine-free cigarettes. Enzyme activity was detected, however, in samples collected during exposure to smoke from high nicotine cigarettes once blood levels of nicotine reached 50-70 ng/ml. The results suggest that cigarette smoke may provoke activation of elastase and indicate the need for further study of any association of cigarette smoking with pancreatic disease. PMID- 6915983 TI - [Molecular forms of human pancreatic elastase 1 in serum and determination by radioimmunoassay. (author's transl)]. PMID- 6915985 TI - [Responses to questions concerning hysterectomy--based on patients' apprehensions and doubts on the procedure]. PMID- 6915984 TI - [Application of midwifery plans at the delivery room of the Arakawa Obstetric Clinic]. PMID- 6915986 TI - [Activities of the "Comprehensive Health Center for Mothers and Infants" during its first year--toward improved health of mothers and children]. PMID- 6915987 TI - [Health instruction concerning menstruation: instruction given by midwives]. PMID- 6915988 TI - [Survey on baby sitters: a survey among mothers of infants and Japanese and American students and pupils]. PMID- 6915989 TI - [A letter from the U.S.A. A cytogenetic study of hydatidiform mole]. PMID- 6915991 TI - [Examination of the newborn infant for external abnormalities]. PMID- 6915990 TI - [Personal application of the Lamaze method]. PMID- 6915994 TI - [Clinical description of myocardial infarction and its management]. PMID- 6915995 TI - [Treatment of myocardial infarction in the field of internal medicine--treatment prior to surgical therapy]. PMID- 6915993 TI - [Experimental studies on dietary elements which suppress the development of salt hypertension (II) Effects of protein intake on sodium metabolism and urinary kallikrein excretion (author's transl)]. PMID- 6915992 TI - [Experimental studies on dietary elements which suppress the development of salt hypertension (I) Effects of potassium salts on sodium metabolism and urinary kallikrein excretion (author's transl)]. PMID- 6915997 TI - [Pre- and post-operative care in surgery of coronary arteries]. PMID- 6915996 TI - [Therapy of myocardial infarction--surgical indication]. PMID- 6915998 TI - [Postoperative monitoring of patients with myocardial infarction--circulatory dynamics and ECG monitoring]. PMID- 6915999 TI - [Preoperative nursing plans and nursing practice for myocardial infarct patients scheduled for surgery]. PMID- 6916000 TI - [Nursing sequence during intra-aortic balloon pumping]. PMID- 6916001 TI - [Nursing during intra-aortic balloon pumping]. PMID- 6916002 TI - [Management and nursing of patients requiring external counterpulsation]. PMID- 6916003 TI - [Nursing of patients with ischemic heart diseases with postoperative complications]. PMID- 6916004 TI - [Postoperative social rehabilitation of patients with myocardial infarct and the role of nursing]. PMID- 6916006 TI - [Science of symptomatology: coma. Etiology and mechanisms involved in coma]. PMID- 6916005 TI - [Conference: postoperative management and care of patients with myocardial infarction in the acute stage]. PMID- 6916009 TI - [Science of symptomatology: coma. Nursing problems and management of patients with hepatic coma]. PMID- 6916008 TI - [Science of symptomatology: coma. Nursing observation and care of patients in coma]. PMID- 6916007 TI - [Science of symptomatology: coma. Classification and physiopathology of coma]. PMID- 6916010 TI - [Risk factors in patients with myocardial infarct and their management]. PMID- 6916011 TI - [Postoperative complications in abdominal surgery and detection of the danger signs (2)]. PMID- 6916012 TI - [Structure of the aging process]. PMID- 6916013 TI - [Psychology of aging]. PMID- 6916014 TI - [Sex of the aged]. PMID- 6916015 TI - [The "dying process" of the aged]. PMID- 6916016 TI - [The aging population and the problems of medical care]. PMID- 6916017 TI - [The focal point in geriatric nursing]. PMID- 6916018 TI - [Management at development of multiple decubitus ulcers and clinical care]. PMID- 6916019 TI - [Care of the aged related to excretion]. PMID- 6916020 TI - [Geriatric nursing: prevention of total inactivity of the aged]. PMID- 6916021 TI - [Home nursing of a patient with senile dementia]. PMID- 6916022 TI - [Geriatric nursing: nutritional care]. PMID- 6916023 TI - [Geriatric nursing: practice of psychological support]. PMID- 6916024 TI - [Geriatric nursing: adjustment of the environment]. PMID- 6916025 TI - [Geriatric nursing: nursing at homes for the aged requiring medical care]. PMID- 6916026 TI - [Current status of the welfare and medical care systems for the aged]. PMID- 6916027 TI - [The outline of the health care legislation for the aged]. PMID- 6916028 TI - [Public facilities for geriatric nursing]. PMID- 6916029 TI - [The man and ape: discussion]. PMID- 6916031 TI - The futures of health education. PMID- 6916032 TI - Decision story strategy: a practical approach for teaching decision making. AB - Teachers are usually very enthusiastic in their evaluations of decision stories. Decision Story Strategies offer a change of pace, promote student involvement and stimulate creative thinking, problem solving and everpresent creative teaching learning opportunities. The real-life problems presented within the structure of a decision story provide meaningful learning opportunities for students. Students begin to think in a broader perspective when considering other points of view and information sources. The Decision Story Strategy used with the Decision-Making Model provides a powerful tool for health educators to develop skills for making and evaluating decisions in an interesting and meaningful context. It may not be a panacea for all health educators, but is an effective strategy for the teacher concerned with developing independent decision makers. Most importantly, students are provided opportunities to solve their present problems as well as develop decision-making skills for the future. PMID- 6916030 TI - In honor of "heart" month: coronary care for the rural nurse - a pilot program. PMID- 6916033 TI - School nurses share a job. PMID- 6916034 TI - Death education within health education: current status, future directions. AB - A national survey was conducted among 205 university level divisions/departments of health education to determine the current status of death education courses within the health education field. Forty-nine college and university health educators currently teaching the course returned usable instruments. Death education receives the same credit, utilizes similar grading systems and is generally managed much like other academic courses. Since the discipline is in its infancy and many teachers are relatively unprepared, respondents called for greater quality control and improved professional preparation. Several concerns accompanying the growth of death education were identified. PMID- 6916035 TI - Group dynamic practices applied to health education. AB - The application of group dynamic techniques as pedagogical tools transforms the classroom into a laboratory for living. In such an environment, concepts relative to man's behavior are not only explained but learned experimentally through the interactive process. Through utilization of this model, the health educator can provide an opportunity for different groups at school to learn about each other's values as well as appreciate their differences. Coping with peer pressure, shyness, others' feelings and defense mechanisms become a part of the learning process. The difficulties of responsible decision making can be periodically examined. Personal expression by a wide range of students is at best difficult to accomplish, and the use of materials and media as motivational devices can not be viewed as ends in themselves. They need to be utilized with regard to a functional analysis of the group dynamic process. Such an analysis should include the teacher's own biases, communication patterns, student roles, reasons for resistance and awareness of sub groups. After making a diagnosis of the system, the teacher is then in a position to orchestrate class behavior through a variety of strategic moves. Such moves include recreating communication channels, controlling stress levels, manipulating seating and modeling desirable behaviors. By incorporating aspects of therapeutic techniques into his/her teaching style, the teacher must not only be knowledgeable but astute and inventive as well. PMID- 6916036 TI - Satisfaction levels of recipients and providers of children's mental health services. PMID- 6916037 TI - Treating adolescent obesity: a pilot project in a school. AB - A weight control program for junior high school students was developed to change eating, exercise and habit patterns. The course included dietary management, physical activity and behavior modification techniques. Classes were structured to emphasize peer group involvement and daily practical application. The curriculum was compiled in a book for educational personnel. The program was tested as a pilot project with a selected group of eighth grade obese adolescent girls and a comparison group. Immediately after the course, the subjects' percent of overweight had decreased; at a subsequent eight-month follow-up, additional losses were noted. The percent of overweight of the girls in the comparison group remained relatively unchanged. While the program was successful with this particular group of students, several key questions, requiring further study, were defined. PMID- 6916038 TI - Contraceptive patterns of college students who experienced early coitus. PMID- 6916040 TI - Education on sexuality: proceed with caution. PMID- 6916039 TI - Policy decisions in scabies control. PMID- 6916041 TI - A shot at success. PMID- 6916042 TI - The death of a classmate: a teacher's experience dealing with tragedy in the classroom. AB - Educators have a responsibility to help children deal with crises, such as death, by doing the following; Educators have a responsibility to help children deal with crises, such as death, by doing the following; (1) acknowledge the reality as soon as possible, (2) provide an environment where children feel comfortable discussing their feelings, (3) provide learning opportunities with curriculum so children may understand what has transpired. It is my hope that the means I used to incorporate the subject of death into the curriculum can be adapted by other educators. Additional resource material can be found in They Need to Know and Discussing Death. PMID- 6916043 TI - Rustia school health promotion model. PMID- 6916044 TI - To parents of children with learning disabilities . . . Some insights from a teacher's perspective. PMID- 6916045 TI - Attention deficit disorder. PMID- 6916047 TI - Athletes score a hit with kids in grades four through eight. PMID- 6916048 TI - Scoliosis screening: an approach used in the school. PMID- 6916046 TI - Social and affective factors associated with adolescent pregnancy. AB - Perceptions associated with pregnancy, including life-expectations, desire for pregnancy and knowledge of the menstrual cycle were assessed in a sample of urban adolescents 13 to 18 years old. Data was obtained from 104 primiparous teens in their second and third trimester of pregnancy. The majority of adolescents, although experiencing an unplanned pregnancy, perceived minimal negative social consequences associated with the pregnancy. Although more than 82% of all teens were aware of where to get birth control, they demonstrated no deep understanding of the menstrual cycle and its relationship to intercourse and only 11% used effective contraception. Of the birth control non-users 74% of the girls reported they did not want to get pregnant. In spite of unprotected coitus, most girls were surprised at conception. PMID- 6916050 TI - [Nursing process: nursing of children with cerebral palsy. Diagnosis and treatment of children with cerebral palsy]. PMID- 6916051 TI - [Nursing process: nursing of children with cerebral palsy]. PMID- 6916053 TI - [Nursing process: nursing of children with cerebral palsy. Evaluation of the nursing process]. PMID- 6916049 TI - [Nursing process: nursing of children with cerebral palsy. Description of the symptoms of cerebral palsy]. PMID- 6916052 TI - [Nursing process: nursing of children with cerebral palsy. Nursing of children with cerebral palsy: case studies]. PMID- 6916054 TI - [Posture change: its significance based on body mechanics]. PMID- 6916055 TI - [Posture change in nursing of patients with consciousness disorders]. PMID- 6916056 TI - [Posture changes of patients confined for an extended time--a case associated with acute pain upon movements of the body]. PMID- 6916057 TI - [Nursing and therapy: exchange transfusion. Exchange transfusion: its theory and application]. PMID- 6916058 TI - [Nursing and therapy: exchange transfusion. Nursing of infants with unconjugated hyperbilirubinemia]. PMID- 6916059 TI - [Assistance of patients with severe burns and nursing personnel--systemic care and nursing actions to ease pain]. PMID- 6916060 TI - [In search of new nursing philosophy. XV. Philosophy of nursing practice--to live true to one's self]. PMID- 6916061 TI - [Nursing of a diabetic patient considered to have a low intelligence level]. PMID- 6916062 TI - [Myocardial infarction]. PMID- 6916063 TI - [Surgical treatment of myocardial infarction]. PMID- 6916067 TI - [Blood pressure determination and the role of nurses--for more accurate determination]. PMID- 6916066 TI - [Blood pressure determination: methods and significance]. PMID- 6916065 TI - [Nursing of patients with myocardial infarction: keypoints in planning of nursing]. PMID- 6916064 TI - [Nursing process of a patient with myocardial infarction]. PMID- 6916068 TI - [Blood pressure fluctuations in postoperative patients with their care]. PMID- 6916069 TI - [Nursing and therapy: rehabilitation equipment (1). Structure of wheelchairs and portable bedpans and their usage]. PMID- 6916070 TI - [Nursing and therapy: rehabilitation equipment (1). Assistance towards independent operation of a wheelchair]. PMID- 6916071 TI - [Nursing of autistic children and the nursing personnel]. PMID- 6916073 TI - [Research report: a trial in clinical training in a two-year nursing course--a report on my nursing ideal]. PMID- 6916072 TI - [Involvement in the work and the attitude of the nurse]. PMID- 6916074 TI - [Test yourself: nursing of patients with obstructive jaundice]. PMID- 6916075 TI - [Pain--a common and yet often misunderstood symptom]. PMID- 6916076 TI - "Evaluation of nursing care". PMID- 6916078 TI - A pilot study: the implementation of the basic concepts of primary nursing care into a Sydney nursing home. PMID- 6916077 TI - Incidence of duplication of interviewing in general nursing applications -- Hunter Region. PMID- 6916079 TI - State superannuation scheme. PMID- 6916080 TI - Pharmacology: a study guide for nurses. PMID- 6916081 TI - Prince Henry Hospital, Centenary Nursing Conference, July, 1981: "Nursing in New South Wales in the 80s". PMID- 6916083 TI - "Nursing in New South Wales in the 80s". PMID- 6916082 TI - "Nursing in New South Wales in the 80s". PMID- 6916084 TI - Deep venous thrombosis. PMID- 6916085 TI - To Erich, with love. PMID- 6916087 TI - DEATH - Does Everyman Acknowledge This Happening? PMID- 6916086 TI - Patients in the balance. PMID- 6916088 TI - Use of a family support centre in a large maternity teaching hospital. PMID- 6916089 TI - Wholeheartedly. PMID- 6916090 TI - A program evaluation framework. PMID- 6916092 TI - Let the R.N. consumer beware -- not all CEU's are equal. PMID- 6916091 TI - Incidence in Room 1114. PMID- 6916093 TI - Necrotising enterocolitis. PMID- 6916094 TI - Care of the premature baby: needs and prospects. PMID- 6916095 TI - Care and treatment of brain injured children. PMID- 6916097 TI - Cleft lip and palate. PMID- 6916098 TI - Neonatal transport in Canadian way. PMID- 6916096 TI - Post-natal loss of libido. PMID- 6916099 TI - Cancer of the cervix. PMID- 6916100 TI - Middle-age: life changes. PMID- 6916101 TI - A post-mature student. PMID- 6916102 TI - One woman's journey through birth. PMID- 6916103 TI - Direct entrant midwives--a "special class". PMID- 6916104 TI - "Are we in danger of extinction"? PMID- 6916106 TI - The RCM--the first 100 years: where are we now? PMID- 6916105 TI - "Turning a dream into reality". PMID- 6916107 TI - Consultation papers from the United Kingdom Central Council for Nursing, Midwifery, and Health Visiting. PMID- 6916108 TI - Plasma prekallikrein determination. PMID- 6916111 TI - What changes in operating theatres: Searle Medical Essay Competition 1981. PMID- 6916109 TI - Something nasty in the undergrowth. PMID- 6916110 TI - How to get help with the Christmas shopping. PMID- 6916112 TI - A teaching tool for apheresis. PMID- 6916114 TI - A dietitian's report on the XVIIIth Congress of the European Dialysis and Transplant Association and the Xth Conference of the European Dialysis and Transplant Nurses Association. PMID- 6916113 TI - Systematic nursing assessment tool for the CAPD client. PMID- 6916115 TI - Interchange: unique medication cart developed for pediatric emergencies helps avoid error--saves lives. PMID- 6916116 TI - On dialyzer reuse. PMID- 6916119 TI - Financial advice: ins and outs of wills require expert advice. PMID- 6916118 TI - Patient assessment: a key to effective dialysis. PMID- 6916120 TI - Self-care for the ESRD patient. PMID- 6916121 TI - Touch a hungry world: nutrition intervention in the Kampuchean refugee crisis: a professional reflection. PMID- 6916117 TI - Nutrition notes: potassium. PMID- 6916123 TI - Nursing considerations: flow control. PMID- 6916124 TI - Nursing responsibilities with arterial access. PMID- 6916122 TI - Intravenous administration of radiosensitizers. PMID- 6916125 TI - Practical considerations in pediatric I.V. therapy. PMID- 6916126 TI - Nursing faculty develop primary care skills. PMID- 6916127 TI - Teaching gerontological nursing in Florida: where do we stand? PMID- 6916128 TI - Mobilizing faculty toward integration of practice into faculty roles. PMID- 6916129 TI - Natural family planning and instructor training. PMID- 6916130 TI - How well do you know your Board of Nursing? PMID- 6916131 TI - Curriculum consultant would you help us out? PMID- 6916132 TI - A decision model - how to determine appropriate community services for the elderly. PMID- 6916133 TI - Characteristics of 23 faculty group nurse practices. PMID- 6916135 TI - Managing community health nurse managers. PMID- 6916136 TI - Nursing education and nursing service: a collaborative model. PMID- 6916134 TI - Transcultural nursing: its progress and its future. PMID- 6916137 TI - Behind the scenes on the Nurse set. PMID- 6916138 TI - "Educational preparation for nursing - 1980.". PMID- 6916139 TI - Test your knowledge of nursing today. PMID- 6916141 TI - Challenge: Robert's skin--will it ever clear? PMID- 6916140 TI - Sharing. Perfect communication. PMID- 6916142 TI - CEU offering. What's behind that I.V. line? PMID- 6916143 TI - Don't let cardiac catheterization strike fear in your patient's heart. PMID- 6916145 TI - Nursing grand rounds. Fighting the frustrations of status asthmaticus. PMID- 6916146 TI - Esophageal cancer. PMID- 6916144 TI - Fear of floating to pediatrics. PMID- 6916147 TI - Learning from mistakes: 20 tips for avoiding medication errors. PMID- 6916149 TI - Skillcheck. On emergency nursing: triage and stress. PMID- 6916148 TI - When baby makes three...challenges. PMID- 6916150 TI - Law for the nurse manager: nurse practitioner. PMID- 6916151 TI - A case study: night supervision. PMID- 6916152 TI - Retention crisis. PMID- 6916154 TI - Transition: student to practitioner. PMID- 6916153 TI - The I.V. nurse. PMID- 6916155 TI - Infection: "A convenient myth?". PMID- 6916156 TI - Absenteeism in nursing. PMID- 6916157 TI - A comparative study of hospital incidents. PMID- 6916159 TI - Art and science of management: ready to snap? PMID- 6916158 TI - Evening supervision: too much for too long. PMID- 6916160 TI - Perspectives in nursing: professional ideas and idealism. PMID- 6916161 TI - Turning staff frustration to satisfaction. PMID- 6916163 TI - The health care regiment? PMID- 6916164 TI - Pre-menstrual tension. PMID- 6916162 TI - Continuing education: a collaborative model. PMID- 6916166 TI - Counselling: a family problem at work-1. PMID- 6916169 TI - Anosmia--an occupational concern? PMID- 6916165 TI - Safety. Chromic acid mist: is enough guidance given?--1. PMID- 6916167 TI - Artificial light and occupational health. PMID- 6916168 TI - Incorporating activity into diabetic self-care. PMID- 6916170 TI - Mobile health testing agencies--it's your choice! PMID- 6916171 TI - Occupational health nursing impacting on environmental sanitation. PMID- 6916173 TI - The occupational health nurse and the process of change. PMID- 6916172 TI - A hearing conservation lesson plan: noise and noise-induced hearing losses. PMID- 6916174 TI - Children vs divorce. PMID- 6916175 TI - At home with traction. PMID- 6916176 TI - Childhood immunizations. PMID- 6916178 TI - Children's response to a belt restraint program. PMID- 6916177 TI - Clearing the occluded auditory canal. PMID- 6916179 TI - Peer review: a practical guide. PMID- 6916180 TI - Pediatric drug information: tests for glucose in the urine: understanding test specificity and interference. PMID- 6916181 TI - Pediatric management problems: gastric teratoma. PMID- 6916182 TI - The counselling dimension of the nurse practitioner. PMID- 6916183 TI - The department chairperson: role, function, and future. PMID- 6916184 TI - Concepts and basic functions of management. PMID- 6916185 TI - Responding to stress: community mental health in the 80s. PMID- 6916187 TI - Challenges of the 80s. PMID- 6916188 TI - Management of common stressors in the later years. PMID- 6916186 TI - Prospects for mental health in the 80s. PMID- 6916189 TI - Stress during the mid-life years. PMID- 6916190 TI - Research about stress--stress about research. PMID- 6916191 TI - Adolescent perception of stressful life events. PMID- 6916193 TI - Diagnosing and counseling bored and confused clients. PMID- 6916192 TI - Coping strategies of neonatal intensive care nurses. PMID- 6916194 TI - Warehouses without walls (or, it didn't end with Dickens). PMID- 6916195 TI - Responding to the challenges. PMID- 6916197 TI - Matching students with clinical experiences by computer. PMID- 6916196 TI - Mentorship for scholarliness: opportunities and dilemmas. PMID- 6916198 TI - Therapeutic communication and clinical instruction. PMID- 6916199 TI - Health assessment skills in the baccalaureate program. PMID- 6916200 TI - Predictors of student success. PMID- 6916204 TI - Dissonance in nurse and patient evaluations of the effectiveness of a patient teaching program. PMID- 6916201 TI - Other worlds of nursing. PMID- 6916202 TI - Developing the evaluation component of a grant application. PMID- 6916203 TI - Career development in nursing: an individual and professional responsibility. AB - Nursing with its variety of career options has much to offer individuals who can capitalize on their skills, growth potential, and professional opportunities through planned career development. More needs to be done, however; as Lysaught observes, "Nursing is the only profession that has no career path related to the intrinsic reason that brought people to the profession in the first place." Working together, nursing service and education must prepare nurses who view nursing as a career and not just as a series of jobs, rewarding nurses for direct patient care services, addressing professional issues that will assist nurses in their career development, providing opportunities for career planning, and "finding ways to share with prospective nurses the excitement and challenge of nursing". PMID- 6916206 TI - Nurse practitioners: the politics of denial. PMID- 6916205 TI - One step forward, sliding back. PMID- 6916207 TI - May we not glow in the dark. PMID- 6916208 TI - Commentary: responses to "Anger: an occupational hazard for nurses" by Bonnie W. Duldt. PMID- 6916209 TI - Dealing with sexism in nursing and medicine. PMID- 6916210 TI - A doctorate--necessary but not sufficient. PMID- 6916211 TI - Communication skills: the interview. PMID- 6916212 TI - What would you do in our shoes? PMID- 6916213 TI - The victims of violence. PMID- 6916215 TI - Orthopaedic management of haemophilic arthropathy. PMID- 6916214 TI - Nursing care study malignant hyperpyrexia - a rare anaesthetic hazard. PMID- 6916216 TI - Four mental hospitals revisited--4. St Augustine's--a breath of fresh air. PMID- 6916217 TI - Lifting and moving patients. 3. A revision training programme. PMID- 6916219 TI - Letter from America. PMID- 6916218 TI - Sources of nurse manpower in the 1980s. PMID- 6916220 TI - The provision of post-basic education in psychiatric nursing. PMID- 6916221 TI - Budgeting for the future. PMID- 6916222 TI - The knowledge base. PMID- 6916223 TI - A helping hand for nurses. PMID- 6916224 TI - My most memorable Christmas. PMID- 6916225 TI - Nursing care study: peripheral vascular disease. PMID- 6916226 TI - Systems of life No 85: systems and signs. Head and neck - 2. Nose and ear. PMID- 6916227 TI - The nursing process in a community nursing service. PMID- 6916228 TI - Worrying trends. PMID- 6916232 TI - One nurse's bright idea. PMID- 6916230 TI - The future of the profession in Scotland. PMID- 6916231 TI - Nursing care study: venturing into the world. PMID- 6916229 TI - Ringing in the New Year. PMID- 6916233 TI - Taboos, traditions and feminism. PMID- 6916235 TI - Dispelling the myths. PMID- 6916234 TI - Disciplinary procedures. PMID- 6916237 TI - Plugging the gap. PMID- 6916236 TI - Treatment of sexual dysfunction by behavioural psychotherapy. PMID- 6916238 TI - On the right course. PMID- 6916239 TI - Nursing care study: a child with a fractured femur. PMID- 6916240 TI - Containers and closures for sterile fluids: the DIN bottle system. PMID- 6916241 TI - Consultation and involvement. PMID- 6916242 TI - A time for change. PMID- 6916245 TI - Written examinations. 1. A question of multiple choice--where are we now? PMID- 6916243 TI - Written examinations. PMID- 6916244 TI - Wound care No. 5. PMID- 6916246 TI - The health visitor in the antenatal period. Research Committee of the Scottish Health Visitors' Association. PMID- 6916247 TI - Written examinations. 2. The format and procedure of the written examinations in district nursing. PMID- 6916248 TI - Theatre nursing care study: extended cortical mastoidectomy and tympanoplasty for chronic otitis media. PMID- 6916249 TI - Scenes from nursing life. 1. You live and learn. PMID- 6916250 TI - A review of pressure sore pathogenesis. PMID- 6916253 TI - A hospice with a difference. PMID- 6916254 TI - Knowing where we stand. PMID- 6916252 TI - No body knows the trouble I've seen. PMID- 6916251 TI - Resolutions. PMID- 6916255 TI - What's up doc? PMID- 6916257 TI - Symposium on pediatric critical care. PMID- 6916256 TI - Paramedics at work--1. Emergency offshore. PMID- 6916258 TI - The nature of pediatric critical care nursing: perspectives of patient, family, and staff. AB - No one would advocate the establishment of a PICU in every hospital. However, in establishing regional pediatric facilities, provisions for critical care for children should be considered. A PICU unit that serves as a referral center, with adequate resources and trained personnel, can be both accessible and cost effective. Pediatric critical care is a challenging arena for the nurse. These children, their families, and the staff form an interdependent triad that continually must try to anticipate and to meet the needs of the participants. The importance of developing care delivery systems that can support each person involved cannot be overemphasized. The ultimate outcome will be a stable setting for patient care that serves to resolve crisis, rather than to precipitate it, preserving the best interests of the patients, family, and staff. PMID- 6916260 TI - Cardiopulmonary resuscitation of children. AB - Cardiopulmonary arrest in children frequently has a respiratory cause. Bradycardia and asystole result from the hypoxia and acidosis of inadequate ventilation. Fortunately, respiratory failure presents warning signs which make early intervention and prevention of arrest a major focus for the nurse. When cardiopulmonary arrest does occur, the nurse must be able to provide the A-B-C's of basic life support, to participate actively in definitive treatment of the arrest, and to assess the child carefully during the post-resuscitation recovery stabilization period. PMID- 6916259 TI - Humanistic nursing care for critically ill children. PMID- 6916262 TI - Critical care of the child with multi-trauma. PMID- 6916261 TI - Critical care of the child with increased intracranial pressure. AB - The nursing care of children with increased intracranial pressure is extremely complex. For children with intracranial pressure monitoring devices in place or for those who are maintained on a barbiturate coma regimen, the nurse must have extensive knowledge regarding the proper operation of the complex equipment that is helping to maintain the child's life. However, no matter how sophisticated the monitoring equipment or no matter what new research protocol is being followed, the child's life is dependent upon the nurse providing care. If the nurse fails to interpret the clinical findings correctly and does not notify the physician promptly, the child may suffer permanent neurologic dysfunction. Furthermore, the nurse must be cognizant of nursing actions--routine activities such as changing the child's position--that could have a dramatic effect on the child's intracranial pressure. Given time, expert nursing care, a multidisciplinary rehabilitation team, and a supportive family, many children who have severely increased intracranial pressures survive the insult without sustaining severe neurologic dysfunction. PMID- 6916263 TI - Critical care of the pediatric cardiovascular patient. PMID- 6916265 TI - Symposium on orthopedic nursing. PMID- 6916264 TI - Critical infections in the pediatric oncologic patient. AB - Over the past three decades, significant progress has been made in the treatment of childhood cancers. These advances derive not only from the effectiveness of the multimodal approach but also because of advances in supportive measures during the critical induction phase of therapy. The impact of disease and therapy on the immune system significantly compromises the child to a critical state. Astute application of the nursing process in assessing, planning, implementing, and evaluating measures to prevent, detect, and treat infectious processes in the granulocytopenic child is one of the critical challenges of nursing the child with cancer. PMID- 6916266 TI - Rehabilitation of common orthopedic problems. PMID- 6916268 TI - Selected aspects of deconditioning secondary to immobilization. AB - Although activity is a normal state of the human body, a variety of orthopedic conditions may necessitate some degree of immobilization. Major deconditioning changes in the cardiovascular system and musculoskeletal system have been identified. The deconditioning changes affecting the cardiovascular system are decreased venous flow, decreased orthostatic tolerance, and decreased work capacity. The deconditioning changes associated with the musculoskeletal system are bone demineralization, altered joint function, and loss of muscle mass, strength, and tone. Possible nursing interventions and their rationales for use with the identified deconditioning changes have been explored. The general goal of any intervention is to minimize the deconditioning that occurs with immobilization. PMID- 6916269 TI - Orthopedic patients in an ambulatory surgery facility. AB - There is no doubt that ambulatory surgical intervention is here to stay. The advantages afforded the patient are substantial. Orthopedic procedures that previously required one to two nights of hospitalization are now routinely performed on an outpatient basis. This is a result of an increase in the use of arthroscopic surgery and an awareness of the importance of preoperative preparation and postoperative follow-up of the patient. Given the usual localized nature of orthopedic problems, the usual pre-existing good health of the orthopedic patient, and his or her desire to return to normal functioning as soon as possible, the scope of what can be accomplished on an ambulatory surgical basis is just beginning to be realized. PMID- 6916270 TI - The sports medicine patient. PMID- 6916267 TI - Polytrauma: the patient, the family, the nurse, and the health team. PMID- 6916271 TI - Shape of nursing world to come through standard care. PMID- 6916272 TI - Curriculum change in nursing-II. Towards a model. PMID- 6916273 TI - People's participation in rural health services. PMID- 6916274 TI - Empathic ability in a psychiatric setting. PMID- 6916275 TI - Curriculum change in nursing-III. Steps in the process. PMID- 6916276 TI - National Awards for nurses--1980. PMID- 6916278 TI - We and our image. PMID- 6916277 TI - Inservice training for nurses in neonatal intensive care unit. PMID- 6916280 TI - Epilepsy: Questions and answers. PMID- 6916279 TI - Epilepsy: Fitting the symptoms. PMID- 6916281 TI - Epilepsy: The positive approach. PMID- 6916282 TI - Child nursing: is it the right time for change? PMID- 6916283 TI - Fathers need their children, too. PMID- 6916285 TI - SENs all change: roll on the new dawn! PMID- 6916284 TI - Students' forum - let's look at a problem: peptic ulcers. PMID- 6916286 TI - Catalyst of change. PMID- 6916287 TI - Maternity care. 2. Emma, Joan, Liz and A.N.Other. PMID- 6916288 TI - Slimming groups: shedding down to size. PMID- 6916290 TI - Infertility: "Can I ever have children?'. PMID- 6916289 TI - Nursing care study - crushed chest injury: crash victim is casualty. PMID- 6916291 TI - Nocturnal enuresis: fears and tears. PMID- 6916292 TI - Careers - accident and emergency: not for the squeamish. PMID- 6916293 TI - Should the sen qualification be abolished? PMID- 6916294 TI - Teamwork that pays dividends. PMID- 6916295 TI - Reorganisation: juggling with the "poor relations". PMID- 6916296 TI - Do you know what your NO does? PMID- 6916297 TI - Peritoneal dialysis: no more needles. PMID- 6916298 TI - Continuity of maternity care. 3. Crisis at night. PMID- 6916300 TI - Nursing auxiliaries: pride and prejudice. PMID- 6916299 TI - Professionalism: striving to be more than Cinderellas. PMID- 6916301 TI - Apathy rules - OK? PMID- 6916302 TI - The 0-5 year old mentally handicapped child. 6. Learning for life. PMID- 6916303 TI - Terminally ill patients: hospice at home. PMID- 6916306 TI - Nursing care study - chronic schizophrenia: time lords, royalty and M15. PMID- 6916305 TI - Nursing care study - Parkinson's disease: we called him Paddington. PMID- 6916304 TI - Allergic patients in hospital: a threat to health? PMID- 6916307 TI - Careers - psychiatric nursing: reaching for the stars. PMID- 6916309 TI - Closed fo stock-taking. PMID- 6916308 TI - Voluntary work for the jobless. PMID- 6916310 TI - St Lawrence's Hospital handbells: jingle bells. PMID- 6916311 TI - Ghosts: strange goings on in hospital. PMID- 6916312 TI - Working at Christmas: there's Noel like Christmas! PMID- 6916314 TI - Seasonal foundations: Santa-the saint who founded hospitals. PMID- 6916313 TI - Festive food: catering for Christmas. PMID- 6916315 TI - Maternity care. 4. Small is intimate. PMID- 6916316 TI - Fire hazards in nurses' homes: from one small spark. PMID- 6916317 TI - Babysitting: a survival guide. PMID- 6916322 TI - Theatre nursing: safety first. PMID- 6916318 TI - Comparison study: live my way. PMID- 6916319 TI - Infantile autism: from speech to print. PMID- 6916320 TI - Nursing care study - tetanus in a leprosy patient: added complications. PMID- 6916321 TI - Mental handicap nursing: a labour of love. PMID- 6916323 TI - Theatre nursing: hot spots. PMID- 6916326 TI - Nursing process: handling the new system. PMID- 6916324 TI - Advice on demand? PMID- 6916325 TI - Nursing process: slow wheel of progress. PMID- 6916327 TI - In defence of the dying. PMID- 6916328 TI - Hypnosis: a cool look at nothing special. PMID- 6916329 TI - Community nursing - Anytown anecdotes 2. On the move. PMID- 6916330 TI - Speech and cleft palate: bridging the gap. PMID- 6916331 TI - Speech and cleft palate: working together. PMID- 6916332 TI - Blood groups. 3. Linked to survival. PMID- 6916333 TI - Nursing care study - dementia: mutual trust and confidence. PMID- 6916334 TI - Paediatric nursing: the young ones. PMID- 6916335 TI - Psychiatry/mental handicap forum 1. - Transatlantic methods of care - psychotherapy: custodian or counsellor? PMID- 6916336 TI - Psychiatry/mental handicap forum 1. Transatlantic methods of care: planning a tailormade approach. PMID- 6916337 TI - The central council opens its doors: welcome! PMID- 6916338 TI - Yvonne Moores: doing a 21-grand job!. Interview by Tamara Ross. PMID- 6916341 TI - Nursing the elderly: promoting changes of attitude. PMID- 6916340 TI - It's a mystery. PMID- 6916339 TI - We've always done it like that. PMID- 6916342 TI - Nursing the elderly: fostering a caring climate. PMID- 6916343 TI - Hypothermia in the neonate: cold can kill. PMID- 6916344 TI - Biochemistry. 1. Detection of iron deficiency. PMID- 6916345 TI - Spinal decompression: relief work. PMID- 6916346 TI - Nursing care study - drug overdose: dealing with an unknown quantity. PMID- 6916347 TI - Health visiting: getting to know you. PMID- 6916348 TI - Changing the face of nurse training. PMID- 6916349 TI - Management forum. 1. First-line managers. PMID- 6916350 TI - Don't shoot the conductors, please. PMID- 6916351 TI - In sickness and in health (service). PMID- 6916352 TI - Seconds running out for round two. PMID- 6916353 TI - This, after three years? PMID- 6916355 TI - Issues in nursing. 2. Angels by any other name. PMID- 6916354 TI - Issues in nursing. 2. Accountability and all that. PMID- 6916356 TI - Community nursing - Anytown anecdotes. 3. Hidden messages. PMID- 6916357 TI - Computers. 1. Name, rank and number. PMID- 6916358 TI - Biochemistry. 2. Build up to an attack. PMID- 6916359 TI - Blindness. 1. Keep an eye on research. PMID- 6916360 TI - Infusion pumps and controllers: made to measure. PMID- 6916361 TI - Multiple disorders: Tilley doesn't live here any more. PMID- 6916362 TI - Careers - midwifery: help for the stork. PMID- 6916363 TI - Radiation therapy as primary treatment for breast cancer. PMID- 6916364 TI - A review of the pulmonary toxicity of cancer chemotherapeutic agents. PMID- 6916365 TI - Family structure and utilization of cancer support groups. PMID- 6916368 TI - The development of a specialized nursing assessment tool for cancer patients. PMID- 6916367 TI - Advanced cancer pain management in a community setting. PMID- 6916366 TI - Registered nurses: perceptions of patients, cancer nurses, and themselves. PMID- 6916370 TI - Issues in chemotherapy administration. PMID- 6916371 TI - Current interventions for doxorubicin extravasations. PMID- 6916369 TI - Environmental influences on the occurrence of chemotherapy-associated nausea and vomiting. PMID- 6916372 TI - Sequence of administering vesicant cytotoxic drugs. PMID- 6916373 TI - Self-help pain control: an information handout for patients using pain medication. PMID- 6916374 TI - Guidelines for nursing care of patients with altered protective mechanisms. By the Oncology Nursing Society, Clinical Practice Committee. PMID- 6916375 TI - More on hazards of working with cytotoxic agents. PMID- 6916376 TI - [Increased granulocyte elastase activity in emphysema. Effect of acute infections on the activity of this enzyme]. PMID- 6916377 TI - Infection control in nursing care: legalities. PMID- 6916378 TI - Hospital fired nurse anesthetist: medical orders problem. Case in point: Young v. Department of Health (405 So. 2d 1209 - LA). PMID- 6916380 TI - Decubitus ulcers in nursing home care: legalities. Case in point: Mellies v. National Heritage, Inc. (630 P. 2d 215 - KA). PMID- 6916379 TI - Legal briefs for nurses: TX: malpractice in cast application; GA: neuroradiology: malpractice alleged. PMID- 6916381 TI - Discriminant analysis to predict graduation--nongraduation in a master's degree program in nursing. AB - Discriminant analysis was used to predict graduation and two categories of nongraduation from readily available admissions data at the University of Kansas nursing master's degree program. The traditional admissions indices, baccalaureate grade point average (GPA) and Graduate Record Examination (GRE) verbal and -quantitative scores, were used as predictors. Criterion categories were composed of 102 graduates, 103 individuals who dropped out of the program, and 65 individuals who were not accepted. The first discriminant function was, chi 2 (6) = 87.567, p less than .0001, and extracted 98% of the variance of the discriminant space. Follow-up procedures using one-way ANOVA's and Scheffe multiple comparisons indicated that the baccalaureate GPA and GRE-verbal and quantitative scores independently differentiated the graduate and dropout groups from the not-accepted group at a statistically significant level (p less than .05). Practical significance of the independent contribution of these variables to group differentiation, as measured by omega 2 was 22% for the baccalaureate GPA, 13% for the GRE-verbal scores, and 10% for the GRE-quantitative scores. Implications for future research are discussed. PMID- 6916382 TI - The effects of nursing education on job effectiveness: an overview of the literature. AB - An overview of the published studies on the effectiveness of a nursing education as it relates to job performance is presented. Selected literature is reviewed and divided into three areas of study: competency, performance, and quality of care. The literature revealed contradictory evidence on the value of baccalaureate nursing education. More important, the review demonstrates a lack of rigorous research in this area. Suggested research directions include the measurement of individual performance rather than the perception of group performance, the development of better instruments, and control of the setting and individual variables that affect job performance. It is recommended that nursing effectiveness be defined in terms of both patient outcomes and nurse performance. PMID- 6916385 TI - [Biliary lithiasis]. PMID- 6916384 TI - [An experiment with packs for a young psychotic]. PMID- 6916386 TI - [Diet in biliary tract diseases]. PMID- 6916383 TI - Construct validity of an empathy instrument. AB - The purpose of the study was to determine the construct validity of the Empathy Construct Rating Scale (ECRS), developed as part of a larger investigation. Two procedures were used: (a) Campbell and Fiske's (1959) multitrait- multimethod approach and (b) factor analysis. The results suggest that the ECRS is a valid and a reliable instrument for measuring empathy. It was shown to have high internal consistency, content validity, and discriminant validity. Results of the factor analysis placed the rating scale in the primary factor, sharing that factor with no other measured trait. The results further suggest that empathy cannot be divided meaningfully into subscales; empathy exists as a whole and all elements must be present in the relationship for it to exist. PMID- 6916387 TI - [Cerebral tumors: clinical and therapeutic aspects]. PMID- 6916388 TI - [Automobile driving for tetraplegics]. PMID- 6916389 TI - [Management of hemoptysis]. PMID- 6916390 TI - [What to say to the family of a depressed patient?]. PMID- 6916391 TI - [Official text: national convention of nurses]. PMID- 6916393 TI - [Classification of cancers]. PMID- 6916392 TI - [Technical memo 28. Puncture-biopsy of the liver]. PMID- 6916395 TI - [Anticancer chemotherapy at home]. PMID- 6916394 TI - [Cancer epidemiology]. PMID- 6916397 TI - [Radiotherapy: necessity--drawbacks]. PMID- 6916396 TI - [Intravenous chemotherapy]. PMID- 6916398 TI - [Cancer immunotherapy]. PMID- 6916399 TI - [Treatment of cancer by hyperthermia]. PMID- 6916400 TI - [Truth, psychiatrist and oncologist]. PMID- 6916401 TI - [The particular role of hospital nurses]. PMID- 6916402 TI - [Nurses' aides..for the best and the worst!]. PMID- 6916403 TI - [Respiratory function tests]. PMID- 6916404 TI - [Living with a respiratory insufficiency: the renewal of oxygen therapy]. PMID- 6916405 TI - [Treatment of acute pulmonary edema]. PMID- 6916406 TI - [Hydatidiform mole and choriocarcinoma]. PMID- 6916407 TI - [Conception and birth of a drug]. PMID- 6916408 TI - [Student nurses undertake the nutrition education of children. From the Nursing School of St. Omer]. PMID- 6916410 TI - [Surgery of the esophagus]. PMID- 6916411 TI - [Professional continuing education: a right for all of us]. PMID- 6916409 TI - [Therapeutics: anti-allergy aerosol bronchodilators]. PMID- 6916412 TI - [Therapeutics: heparin]. PMID- 6916413 TI - [To improve the quality of care: the audit]. PMID- 6916415 TI - [Psychology of mothers faced with the immediate hospitalization of their newborn]. PMID- 6916414 TI - [4 weeks less]. PMID- 6916417 TI - [Quality of health care]. PMID- 6916418 TI - [Investigation of anemia in general practice]. PMID- 6916419 TI - [Treatment of common disk sciatica]. PMID- 6916420 TI - [Emergencies in ophthalmology]. PMID- 6916421 TI - [Home care services of an anticancer center]. PMID- 6916422 TI - [Is reviewing easy?]. PMID- 6916416 TI - [Hemodynamic monitoring in intensive care units]. PMID- 6916423 TI - [A first module truly in common]. PMID- 6916424 TI - [Nursing initiative-pivot of professional practice]. PMID- 6916425 TI - [White shirts]. PMID- 6916426 TI - [The Red Cross must participate in the fight against torture]. PMID- 6916428 TI - [Pharmacology and therapeutics. Anticoagulants]. PMID- 6916427 TI - [Annick or to be 9 years old and to have cancer!]. PMID- 6916430 TI - [Nursing between the future and the reality]. PMID- 6916429 TI - [Nursing care in the coming century]. PMID- 6916431 TI - [Antiseptics and disinfectants]. PMID- 6916432 TI - [Nursing care of the airways]. PMID- 6916433 TI - [Nursing in a new century: a structure for the future. Health services for today: a challenge for the nurse]. PMID- 6916435 TI - [Changing intravenous administration every 24 hours]. PMID- 6916434 TI - [Practical management of nutrition in the aged]. PMID- 6916436 TI - [An educational experience in intensive care]. PMID- 6916437 TI - [Health care differences between Africa and Europe]. PMID- 6916438 TI - [Infection and decrease in defense caused by an injection without asepsis]. PMID- 6916439 TI - [The crisis of the western medical system]. PMID- 6916440 TI - [The nurse and the fool]. PMID- 6916441 TI - Sex Q & A: frank answers to your most delicate patient-counseling questions. PMID- 6916442 TI - The subtle art of really good injections. PMID- 6916443 TI - Those miraculous digital replantations. PMID- 6916444 TI - Blushing on the inside: a new look at hypertension. PMID- 6916446 TI - The fine art of giving a physical: taking a close look at the eye. PMID- 6916445 TI - An innovation in decubitus treatment sparks debate. PMID- 6916447 TI - Confessions: why we nearly lost Miss Mitchell. PMID- 6916448 TI - Neurodiagnostic studies: pre- and post-procedure care. PMID- 6916449 TI - Adrenal patients, Part II. Kid-glove care in pheochromocytoma. PMID- 6916450 TI - Legally speaking: how to force that on-call MD to respond. PMID- 6916451 TI - Sound off! Nurses who just don't care. PMID- 6916452 TI - Leadership at work. Picking winners: a primer for hiring staff. PMID- 6916454 TI - Moving away from the bedside? PMID- 6916456 TI - Will the computer be the new "nurses' aid"? PMID- 6916455 TI - Nurses screen almost 3,000 "boat people". PMID- 6916453 TI - Nursing with conscience. PMID- 6916458 TI - Rights. Duties. Obligations. Abstract words to many, but they are fundamental to a profession such as nursing. PMID- 6916457 TI - Nursing the acutely-ill elderly. PMID- 6916460 TI - [A new future for hospitals?]. PMID- 6916459 TI - [Education attempt at nursing]. PMID- 6916462 TI - [You are broken, plastic yourself!]. PMID- 6916464 TI - [Complementary studies in arteriopathies of the lower extremities]. PMID- 6916463 TI - [Diagnosis of arteritis of the lower extremities]. PMID- 6916461 TI - [Developing home care services for the aged]. PMID- 6916465 TI - [Managing the risk factors of arteriopathy]. PMID- 6916466 TI - [Medical treatment of arteriopathies of the lower extremities]. PMID- 6916467 TI - [Surgical treatment of arteriopathies of the lower extremities]. PMID- 6916468 TI - [Arteritis of the lower extremities: epidemiology, risk factors, evolution]. PMID- 6916469 TI - [Heparin]. PMID- 6916470 TI - [Hygiene of living, rehabilitation, home care services]. PMID- 6916471 TI - [Mister P's arteritis]. PMID- 6916472 TI - [Aggression in professional-patient relations]. PMID- 6916473 TI - [Evolution of arteriopathy of the lower extremities]. PMID- 6916474 TI - [Development of language and communication in children]. PMID- 6916476 TI - [Language and behavior, two means of communication]. PMID- 6916477 TI - [Acute alcoholic intoxication: scorned but sometimes serious]. PMID- 6916475 TI - [Language and communication disorders in children]. PMID- 6916480 TI - [Sexuality of the young child]. PMID- 6916479 TI - [Communication and language]. PMID- 6916478 TI - [Language and communication disorders in adults]. PMID- 6916481 TI - [Sexuality of the child and of the adolescent]. PMID- 6916482 TI - [Brief presentation on bio-energy]. PMID- 6916483 TI - [It is not only the patient who should develop himself]. PMID- 6916484 TI - [Drug information: malaria prophylaxis recommendations]. PMID- 6916486 TI - [Comments on the evaluation model used in the management plan: a theoretical vision which can be applied in practice]. PMID- 6916485 TI - [Analysis exercises within health and nursing care: one can analyse a well defined area with few tools]. PMID- 6916488 TI - [Strict ethical requirements for profession and research]. PMID- 6916487 TI - [Civil servants' rights now also for the municipal department]. PMID- 6916489 TI - [Consequences of choice of principles in education]. PMID- 6916490 TI - [Professional Information Series No. 1 about changes in nursing's attifude and behavior: good intentions are of no benefit it they remain unused]. PMID- 6916492 TI - [Executive Board meeting 10-11 November 1981: nurses are exposed to constant education pressure]. PMID- 6916493 TI - [The correct name for primary nursing is individual nursing care]. PMID- 6916491 TI - [Evaluation of nursing care]. PMID- 6916494 TI - [Consequence of choice of principles in education. 2. Representation of induction and deduction]. PMID- 6916495 TI - [What nurses should observe about the general election]. PMID- 6916497 TI - [Drug information: benoxaprofen (Bexopron), fenbufen (Cinopal). Nonsteroid anti inflammatory drugs]. PMID- 6916498 TI - [Scandinavian Nursing Cooperative's delegates' meeting 1981 in Norway: international cooperation has remained more far-flung]. PMID- 6916499 TI - [Consequences of choice of principles in education. 3. Reflections about consequences of choice of teaching methods]. PMID- 6916496 TI - [Report of a month' study visit in a maternity department of a modern Belgian hospital: birth experiences we call up-to-date are darkly medieval]. PMID- 6916500 TI - [Guidelines which are contradictory and unreliable for safety]. PMID- 6916502 TI - [It is now that we should start planning]. PMID- 6916503 TI - [What do you mean with the models in report 933?]. PMID- 6916501 TI - [Strain on the locomotor system in daily life: more important that nurses learn to know their body]. PMID- 6916504 TI - [Scandinavian Nurses' Cooperative's delegates' meeting 1981 in Norway: Scandinavian nurses can exert influence in joint action taking]. PMID- 6916505 TI - [Nurse sent out by the Central People's Cooperation to Kenya: few means and possibilities but nevertheless help]. PMID- 6916506 TI - [Health Administration on health visitors' classification of need: general understanding and interest are to be expected]. PMID- 6916507 TI - [Formalized cooperation between primary and secondary health services: more continuity of care between hospital and home]. PMID- 6916508 TI - [Drug information: pregnancy and drugs. I]. PMID- 6916509 TI - [Nursing research: subject for meditation for nurse researchers in countries such as Denmark]. PMID- 6916510 TI - [Hospital fire in Svendborg. We pulled quilts over the children before they were moved through the smoke]. PMID- 6916511 TI - [Comments on the article about the hospital fire: it should be a strong warning to all hospitals]. PMID- 6916512 TI - [Team work with the use of common knowledge and phantasy]. PMID- 6916513 TI - [We know but little about the aged and what it is like to be old. Interview by Ulla Dietl]. PMID- 6916518 TI - The genetics of canine behavior. PMID- 6916517 TI - Glue vs. sutures. PMID- 6916515 TI - [Hospitals can therefore burn]. PMID- 6916516 TI - Cardiac glycosides and hepatic failure. PMID- 6916514 TI - [Study concerning skin disinfection in the operating department: no research about the use of iodine or alcohol]. PMID- 6916519 TI - The computer: a veterinary guide to microprocessing. PMID- 6916520 TI - Feline urologic syndrome: incidence, diagnosis, and treatment. PMID- 6916521 TI - Prednisolone as a treatment for chronic active hepatitis. PMID- 6916522 TI - Infectious canine hepatitis (two case reports). PMID- 6916523 TI - Oral lesions of histoplasmosis in a dog. PMID- 6916524 TI - Use of a modified-RIA test kit to detect hypothyroidism in dogs. PMID- 6916525 TI - Preservation responses in a dying military macaw. PMID- 6916526 TI - An unusual site of Corynebacterium renale infection in a deer. PMID- 6916527 TI - Xylazine analgesia in cattle. PMID- 6916528 TI - A suspected case of phlegmonous stomatitis caused by Staphylococcus spp in a Hereford bull. PMID- 6916529 TI - Reproduction and breeding management of does. PMID- 6916531 TI - Burnout. PMID- 6916532 TI - Communication--2. Observation: are things really as they seem? PMID- 6916530 TI - Parasite control in horses: a summary of contemporary drugs. PMID- 6916533 TI - Why do carnlvores eat grass? PMID- 6916534 TI - Cyanoacrylate adhesives don't hold. PMID- 6916535 TI - A litigation primer for veterinarians. PMID- 6916536 TI - Effects of monensin on coccidiosis in ruminants. PMID- 6916537 TI - Hematoma of the bovine penis: a technique for predicting successful surgical correction. PMID- 6916538 TI - Evaluation and management of tonsillitis & pharyngitis in dogs. PMID- 6916539 TI - Autoimmune hemolytic anemia in a dog. PMID- 6916540 TI - Removal of gastric foreign bodies using flexible fiberoptic endoscopy. PMID- 6916541 TI - Applied kinesiology: its use in veterinary diagnosis. PMID- 6916543 TI - Kyphosis in a Mealy Amazon Parrot. PMID- 6916542 TI - Helminth injections of dogs in central Texas. PMID- 6916544 TI - Hypocalcemic tetany induced by piperazine citrate in a mountain lion. PMID- 6916545 TI - Treatment of coffin bone rotation in draft horses. PMID- 6916547 TI - Entropion in the Shar Pei. PMID- 6916546 TI - Field test of fenbendazole and trichlorfon in horses. PMID- 6916548 TI - Article is unprofessional. PMID- 6916549 TI - Modifying a cat's behavior. PMID- 6916551 TI - Cracking open a puppy bank. PMID- 6916550 TI - Clinical evaluation of a new radiographic contrast agent: diatrizoate meglumine 60%. PMID- 6916552 TI - Feline giardiasis (a case report). PMID- 6916553 TI - Clinical use of veterinary acupuncture. PMID- 6916554 TI - Urethral adenocarcinoma in a dog. PMID- 6916556 TI - Use of fluprostenol to manage the equine estrous cycle. PMID- 6916555 TI - Duration of immunity in dogs inoculated with an inactivated feline parvovirus vaccine. PMID- 6916558 TI - Japanese yew: a toxic ornamental shrub. PMID- 6916557 TI - Equine ulcerative lymphangitis caused by Pasteurella hemolytica (2 case reports). PMID- 6916559 TI - Efficacy of swine erysipelas vaccine given simultaneously with medicated rations. PMID- 6916560 TI - Surgical repair of a rectal fibroma in a bull. PMID- 6916561 TI - Polycystic disease of the kidneys in a stripped skunk and Mongolian gerbil. PMID- 6916562 TI - Visceral lymphoblastic leukosis in an African gray parrot. PMID- 6916563 TI - Communication--1. Creative thinking: key to optimal communication. PMID- 6916564 TI - That teratogenic cow ... PMID- 6916565 TI - A process of bereavement resolution: uncoupled identity. PMID- 6916566 TI - Choosing an appropriate statistical test of significance for a nursing research hypothesis or question. PMID- 6916568 TI - Reliability of graduate nursing students in coding health problems by use of ICDA. PMID- 6916567 TI - Coping strategies of hospitalized school-age children. PMID- 6916570 TI - Defining the role of the nurse practitioner. PMID- 6916571 TI - Publish or perish: how to accomplish the former and avoid the latter. PMID- 6916569 TI - Ethical dilemmas in nursing: a survey. PMID- 6916572 TI - Ethical issues in nursing research. PMID- 6916573 TI - Strategies for teaching nursing research: a guide to the process of preparing a research proposal. PMID- 6916575 TI - [Risks in the reorganization of the National Social Welfare Board. Quality control of health care could deteriorate]. PMID- 6916574 TI - Using research in practice: extending school nursing roles and services in a hypertension screening and follow-up program. PMID- 6916576 TI - [Here practical nurses manage work]. PMID- 6916578 TI - [Gun Lundblad, chief safety representative in Goteborg: it requires respect for the promotion legislation. Interview by Kristina Lindgren]. PMID- 6916577 TI - [Primary nursing]. PMID- 6916579 TI - [Cancer tests scare women needlessly. Interview by Inger Lernevall]. PMID- 6916580 TI - [This how it is to be a laboratory assistant in a refugee camp with few resources]. PMID- 6916581 TI - [Primary nursing: this is how it works in practice]. PMID- 6916582 TI - [Private physicians boycott nursing education]. PMID- 6916584 TI - The law and the lamp: minor difficulties? PMID- 6916583 TI - In vitro evaluation of the antibiotic susceptibility of Streptococcus pneumoniae: pneumococci relatively resistant to penicillin in Brussels. PMID- 6916586 TI - Use of 3 percent hexachlorophene baths to control patient colonization by oxacillin and aminoglycoside-resistant Staphylococcus aureus. PMID- 6916585 TI - The "hit and miss" of meeting our patients' psychosocial needs. PMID- 6916587 TI - MRSA in a hospital social worker. PMID- 6916588 TI - Risk of infection associated with the use of Broviac and Hickman catheters. AB - A 4-month prospective medical records review was done to investigate the occurrence of central venous catheter-related infections. Nineteen percent of the patients developed a catheter-related infection, either local infection at the insertion site (8.9%) or septicemia (10.0%). There were 7.5 catheter-related infections per 1000 catheter-use days. The infection rate was five times greater in patients with Hickman catheters than in those with Broviac catheters (p = 0.01). Analysis by the life table approach produced a linear curve of catheter related infection over time, suggesting a constant dialy risk of catheter-related infection. PMID- 6916589 TI - A program for infection surveillance utilizing an infection control liaison nurse. AB - Today's infection control programs require a practical, efficient, and effective surveillance system. The Epidemiology Section of a 650-bed, university-affiliated hospital has implemented a two-phase approach. Phase I is surveillance by service. Each service receives a minimum of 2 months' concentrated surveillance, with critical care units monitored each month. The entire hospital is covered within a year. Monthly statistics are issued for each surveyed service and the individual patient units within that service. Phase II involves the infection control liaison nurse (ICLN). An ICLN, established in each patient unit, monitors infection control practices and acts as a liaison between the unit and the epidemiology section. Selected candidates are trained by the epidemiology section. The ICLN aids in more immediate identification of problems and better monitoring of aseptic practices. This approach is effective and manageable. Better understanding of unit problems result in more relevant educational programs with time to conduct additional activities. Statistics have more meaning and support for infection control is improved. PMID- 6916590 TI - Rubella outbreak in a prenatal clinic: management and prevention. AB - An obstetrician and two staff members developed rubella and exposed 56 susceptible pregnant women in a large prenatal and family planning clinic. Two women (3.6%) developed rubella at 27 and 38 weeks' gestation and delivered uneventfully. Sixteen hundred clinic and hospital employees were tested, with 79% of the total and 48 of 59 (81.4%) OB/GYN personnel showing prior infection and/or immunity (HAI titer greater than or equal to 1:8). Of those susceptible, all obstetrical and most other personnel were vaccinated and removed from high risk areas until immune. Our management of a rubella outbreak and recommendations on hospital and clinic policy to avoid potential health problems are discussed. PMID- 6916592 TI - New RN exam based on nursing process. PMID- 6916591 TI - Comparison of surveillance and control activities of infection control nurses and infection control laboratorians in United States hospitals, 1976-1977. AB - To study the impact of the professional background of infection control personnel, we compared the characteristics and activities of 107 infection control nurses (ICNs) with those of 13 infection control laboratorians (ICLs), all in hospitals with 300 beds or more. Although the two groups performed similarly in many respects. ICNs spent more time teaching, whereas ICLs spent more time and appeared more proficient in investigating outbreaks. Staff nurses at hospitals with ICNs found the infection control person more visible on the wards and more available for discussing infection control matters. ICNs appeared less hesitant to speak up to personnel not following correct handwashing techniques. ICNs and ICLs appear to offer different skills that should be considered when filling different infection control positions. PMID- 6916593 TI - Budget cuts curtail vital programs, nurses report. PMID- 6916594 TI - As I see it. Teacher tells how to share convention with students. PMID- 6916595 TI - Who cares for the carers? PMID- 6916597 TI - Salbutamol. PMID- 6916596 TI - The nurse and the law: consent Pt. II. PMID- 6916598 TI - Tuberculosis: still here and still lethal. PMID- 6916599 TI - Changes in the nature of nursing. PMID- 6916600 TI - The role and influence of nurses at a Federal Government level. PMID- 6916601 TI - The challenge of extended care: a Victorian view. PMID- 6916602 TI - A 'play at home' program. PMID- 6916604 TI - Professional attitudes of R.N.s to human sexuality. PMID- 6916603 TI - An advanced psychiatric nursing program at P.I.T. PMID- 6916606 TI - Magnesium ion inner sphere complex in the anticodon loop of phenylalanine transfer ribonucleic acid. AB - The binding of Ca2+ and Mg2+ to tRNAPhe is analyzed by equilibrium titrations and temperature-jump measurements using the Wye base fluorescence as a label. Titration experiments starting with the folded structure of the tRNA (high salt and low temperature) show that Ca2+ and Mg2+ binding detected by Wye base fluorescence changes is associated with equilibrium constants between 1 x 10(3) and 3 x 10(3) M-1. The binding of Ca2+ leads to an increase of the relaxation time associated with a conformation change of the anticodon loop and to a decrease of the corresponding amplitude. These data are represented quantitatively by a two-step reaction scheme with a preferential binding of Ca2+ to one of the anticodon conformations. When Mg2+ is added, an extra relaxation process is observed with time constants around 1 ms. This process demonstrates the formation of a Mg2+ inner sphere complex. Relaxation time constants and amplitudes are represented quantitatively by a three-step reaction scheme. Mg2+ binds preferentially to one of the anticodon conformations. In the absence of Mg2+, these conformations are populated almost equally with a transition rate constant around 5 x 10(3) s-1. The Mg2+ inner sphere complex is formed with a relatively low rate constant of (1--2) x 10(3) s-1, indicating a conformational barrier. These data strongly suggest that the Mg2+ site analyzed in the present investigation corresponds to the anticodon site with a distorted octahedral coordination characterized by X-ray analysis. The results are discussed in terms of the anticodon function and also with respect to their implications upon Mg2+ binding to nucleic acids in general. PMID- 6916609 TI - Good news ... for a change! PMID- 6916610 TI - Six steps to planning better nursing grand rounds. PMID- 6916607 TI - Codon-induced transfer ribonucleic acid association: quantitative analysis by sedimentation equilibrium. AB - It is shown by measurements of the sedimentation equilibrium that binding of the codon UUC to tRNAPhe from yeast induces an association of tRNA molecules. Sedimentation measurements at different concentrations demonstrate that the tRNA codon complexes form dimers. The sedimentation profiles are analyzed quantitatively in terms of a simple monomer-dimer model as well as a model which considers the sedimentation of four species (tRNA, tRNA.UUC, (tRNA.UUC)2, and UUC) separately. The information resulting from the conservation of mass relation is used directly in the determination of equilibrium constants via integration o the sedimentation profiles. Using this procedure, we determine the equilibrium constants for dimerization of the tRNAPhe.UUC complex, KD = 8.6 x 10(4) M-1, and for the binding of UUC to tRNAPhe, KL = 1800 M-1 (5 degrees C). The large free energy for dimerization of the tRNA-codon complex suggests that interactions between adjacent tRNAs are important for the ribosomal translation process. PMID- 6916608 TI - [Conformation and Raman spectra of the transfer ribonucleic acid, tRNAAsp]. AB - The structure of yeast tRNAasp in aqueous solution has been studied in sight of Raman spectra recorded between 5 and 82 degrees C. A conformational change is evidenced at 20 degrees C and an endomelting is found around 70 degrees C. This melting temperature, much higher than in tRNA-phe (near 50 degrees C) is interpreted by the presence of a higher number of G-C bases in t RNA asp. At a same temperature, the Raman spectrum of a tRNAasp crystal is quasi-identical than that of an aqueous solution, indicating a high structural similarity except bands corresponding to G, C bases which show a more effective stacking of these bases in the solid. PMID- 6916611 TI - Psychomotor skill acquisition in nursing students in Canada and the U.S. PMID- 6916605 TI - Rat liver mitochondrial lysine tRNA (anticodon U*UU) contains a rudimentary D-arm and 2 hypermodified nucleotides in its anticodon loop. PMID- 6916612 TI - Attitudes of Chinese women towards sexuality and birth control. PMID- 6916613 TI - Culture conflict: a study of the problems of Chinese immigrant adolescents in Canada. PMID- 6916614 TI - Something had to be done. PMID- 6916615 TI - And father makes three ... PMID- 6916616 TI - The future belongs to those who plan for it. PMID- 6916617 TI - The voice of nursing an "unscientific" commentary on the state of the art. PMID- 6916618 TI - You and the law: when your patient wants to know. PMID- 6916619 TI - Influence of environmental factors on exercise and activity of cardiac patients. PMID- 6916620 TI - Caring for themselves. PMID- 6916621 TI - Health visitor--another rude word? PMID- 6916622 TI - Pressure sores: pressure for progress. PMID- 6916623 TI - Pressure sores: the healing processes, helping healing. PMID- 6916624 TI - Carers need care. PMID- 6916625 TI - [In search of constant gentleness]. PMID- 6916627 TI - [Interpretation of the "Process of the Nursing Planning" - a holistic approach in nursing and a nursing model]. PMID- 6916626 TI - [Observation and nursing of a postoperative patient with consideration toward his individuality (2). A study on the evaluation of the nursing check list]. PMID- 6916628 TI - [Removal of the dead: from room to morgue]. PMID- 6916629 TI - [Initial evaluation of the needs for training in the attitude to death]. PMID- 6916630 TI - [In search of the method of conveying the philosophy of nursing to students - 10 years of experience and the encounter with nursing theory]. PMID- 6916631 TI - [Women's role and nursing - a lesson in folk medicine]. PMID- 6916632 TI - [Impression of Japan]. PMID- 6916633 TI - Patient education: the challenge, the opportunity. PMID- 6916634 TI - Infectious arthritis. PMID- 6916635 TI - Drug-induced nephrotoxicity. PMID- 6916637 TI - [Educational apprenticeship in bibliographic reference: traditional method]. PMID- 6916638 TI - [Rooming-in system]. PMID- 6916636 TI - Effects of dexamethasone on excretion of urinary kallikrein and urinary protein in Dahl salt-sensitive and salt-resistant rats. AB - The effect of glucocorticoid treatment on urinary kallikrein excretion was assessed in Dahl salt-hypertension susceptible (S) and salt-hypertension resistant (R) rats. A single dose of dexamethasone (100 micrograms) caused a marked water diuresis and a slight decrease in urinary kallikrein excretion in both S and R rats. A single dose of dexamethasone also caused the S rat to excrete massive amounts of protein into the urine, almost 3-fold higher than S rats treated with oil; the effect on R rat urinary protein was similar, but less severe. Daily administration of dexamethasone (100 micrograms/day) for 7 days caused marked suppression of urinary kallikrein excretion in both S and R rats. Increased urinary protein following chronic treatment was still evident in the dexamethasone-treated S rats but not in the dexamethasone-treated R rats. Chronic glucocorticoid treatment probably inhibits urinary kallikrein activity by suppressing pituitary and adrenal function which would remove the stimulatory effect of aldosterone on urinary kallikrein excretion. There was no evidence for a stimulatory role of glucocorticoids on urinary kallikrein. PMID- 6916639 TI - [Pre and postoperative visiting of patients]. PMID- 6916640 TI - [University Hospital of PUC (Papal Catholic University)]. PMID- 6916641 TI - Effects of geranylgeranylacetone on gastrointestinal secretion in rats. AB - The effects of geranylgeranylacetone (GGA), a new acyclic polyisoprenoid with a novel antiulcer action on gastrointestinal secretion were studied in rats. Intraduodenal administration of GGA (1-30 mg/kg) dose-relatedly reduced the gastric acid secretion caused by pentagastrin, histamine or insulin. On the other hand, GGA (3-30 mg/kg i.d.) dose-relatedly increased pancreatic secretion but did not affect biliary secretion. The above-mentioned findings seem consistent with the further findings that GGA depressed a plasma gastrin level enhanced by insulin while in increased the basal level of plasma secretin. These pharmacological features found in the present studies may partially, at least, account for the mechanism of GGA antiulcer action. PMID- 6916642 TI - An improved pharmacological procedure for depletion of noradrenaline: pharmacology and assessment of noradrenaline-associated behaviors. AB - A pharmacological procedure which initially depletes noradrenaline (NA), dopamine (DA) and 5-hydroxytryptamine (5-HT) but permits repletion of DA and 5-HT was used to evaluate the role of NA in feeding behavior and intracranial self-stimulation behavior. The rapid-onset 'reserpine-like' vesicular depletion drug RO 4-1284 reduced NA and 5-HT 99% and DA 90% in rat forebrain within 1 h after administration with complete repletion of all amines occurring within 6 to 12 h. Treatment with the dopamine-beta-hydroxylase inhibitor FLA-63 significantly reduced NA (maximum depletion 42%) but not DA or 5-HT over the 12 h period of evaluation. The two drugs together produced a specific depletion of NA. Forebrain levels of NA in subjects pretreated with FLA-63 then given RO 4-1284 0.5 h later were reduced to 2% of control values for 8 h while vesicular stores of DA and 5 HT were repleted 77% and 93%, respectively, within 8 h after administration. Selective depletion of NA, in this manner, reduced deprivation induced food intake and lateral hypothalamic self-stimulation. PMID- 6916644 TI - [Aortic aneurysms]. PMID- 6916643 TI - [Prevention and treatment of hypertensive states in children and adolescents (2)]. PMID- 6916645 TI - [Lyell's syndrome in drug disease]. PMID- 6916646 TI - [Kraurosis and leukoplakia of the external female genitalia]. PMID- 6916647 TI - [Inflammatory diseases of the male urinary canal and genitalia]. PMID- 6916650 TI - [Clinical aspects and treatment of ichthyosis]. PMID- 6916649 TI - [Candidiasis]. PMID- 6916651 TI - [Nosebleeds]. PMID- 6916648 TI - [Further improvement in public health in light of the decisions of the 26th Congress of the CPSU]. PMID- 6916653 TI - [Organization of the holding of feldsher conferences]. PMID- 6916652 TI - [Hygiene training and education of women on the job]. PMID- 6916654 TI - [Marriage and family counseling]. PMID- 6916655 TI - [Industrial hygiene of workers in electroplating shops]. PMID- 6916656 TI - [Examination method with cardiology patients]. PMID- 6916658 TI - [Prenatal interaction between mother and child: "prenatal psychology"; its position in obstetrics of today]. PMID- 6916657 TI - The Bf system in diabetes--gene interaction or linkage disequilibrium? PMID- 6916659 TI - [The effect of fenoterol on the incidence of arrhythmias during Caesarean section (author's transl)]. AB - Beta-sympathomimetic tocolysis is an important part of modern obstetric therapy. Severe cardio-vascular complications have been described however, when inhalational anaesthesia was given following fenoterol-verapamil therapy. Alterations in clinical; cardiovascular parameters were measured in a prospective study on healthy women who had to undergo caesarean section and who had been treated with fenoterol-verapamil until the time of anaesthesia. The patients were given either halothane or enflurane as inhalational anaesthetic, and either an atropine premedication or none at all. Severe cardiovascular disturbances such as frequent extrasystole, arrhythmias or marked falls in blood pressure were not noted either during induction, whether following atropine or not, or during the course of anaesthesia with either 0.5 vol% halothane or 1.0 vol% enflurane. PMID- 6916660 TI - [Pentazocin as an obstetric analgesic (author's transl)]. PMID- 6916661 TI - [Procedures in the pregnant and non-pregnant uterus under sonographic control (author's transl)]. AB - Several procedures during pregnancy under ultra-sonographic control are described. Amniocentesis and puncture of the fetus may be done accurately without too much problems when a multi-element ultra-sound scanner is used for sonographic control. The principle of manipulation with ultra-sonographic control may be used for curettage. Instruments within the uterus may be localized and their movements can be submitted to continual visual control. A curettage under sonographic control may reduce the risk of the curettage in cases of uterine anomalies, anomalies of the position or unusually soft uteri. PMID- 6916662 TI - [Results of the cytological examinations of cells from the uterine cavity (author's transl)]. AB - A new method for obtained cytological material from the uterine cavity with the Exploret-Fatol is described. The results in 38 patients with atypical vaginal bleeding is reported. In 4 women the tight cervical canal necessitated general anaesthesia. In all cases adequate cytological material for examination was retrieved from the endometrium. It was not always possible to differentiate endometrium from endocervical cels by their morphology. Nevertheless all benign premalignant lesions and all malignant lesions of the endometrium were cytologically recognized. This method may find application in many high risk patients and therefore improve the early diagnosis of carcinoma of the endometrium. The methods success depends upon good knowledge of endometrial cytology by the examining cytologist. PMID- 6916663 TI - [Endometriosis of the large bowel (author's transl)]. PMID- 6916664 TI - [Actinomycosis of the female genital tract in wearers of intra-uterine contraceptive devices (author's transl)]. AB - Two cases of actinomycosis of the upper female genital tract in wearers of intrauterine contraceptive devices are reported. The cases were both observed within a short time interval. In the first case the disease had spread to large portions of the minor pelvis and shown the expected symptoms and signs. In the second case the actinomycosis was confined to the endometrium. The rarity of pelvic actinomycosis and the differential diagnosis with malignant tumours of the female genital tract prompted us to examine this infection in detail. Apparently pelvic actinomycosis is more common than suspected. PMID- 6916665 TI - [On the prevention of paresis of the femoral nerve following abdominal gynaecological operations (author's transl)]. AB - Self retaining retractors may cause paresis of the femoral nerve following abdominal gynaecological operation. In principle all types of retractors may be the cause. Self retaining retractors with small and long lateral blades are especially dangerous. The paresis is caused by direct and indirect pressure of the lateral blades of the retractor on the nerve. The discrepancy between large and deep retractor blades and thin abdominal walls predisposes to paresis of the femoral nerve. Thin underweight patients are especially in danger. In addition, a transverse incision, too much tension and a long duration of the operation are predisposing factors. The prevention is possible by knowledge of the case and a careful selection of the lateral blades of the retractor in accordance with the individual anatomy encountered. Sometimes manual retractors have to be used instead of a self retaining retractor. PMID- 6916666 TI - [Priming of the cervix at term with 3 methods: the oxytocin infusion, the administration of prostaglandin F2 alpha gel and the administration of prostaglandin E2 gel into the cervical canal (author's transl)]. PMID- 6916667 TI - [Phantom sensations following mastectomy (author's transl)]. PMID- 6916668 TI - Unstable drug resistance in Staphylococcus aureus M4. PMID- 6916669 TI - Why response to medication changes with age. PMID- 6916670 TI - The older adult and drug therapy: Part one. Legal guidelines. PMID- 6916671 TI - Prescriptive authority for nurse practitioners. PMID- 6916672 TI - The older adult and drug therapy: Part one. Special considerations for the community-based elderly. PMID- 6916673 TI - Problems of a pill taker. PMID- 6916674 TI - Storing medications safely. PMID- 6916675 TI - 70+ and going strong: Ed and Irene Martin, hosts for a new age. PMID- 6916676 TI - The older adult and drug therapy: Part two. Meaning of the medication: clue to acceptance or rejection. PMID- 6916677 TI - The older adult and drug therapy: Part two. The pharmacist's evaluation. PMID- 6916678 TI - The older adult and drug therapy: Part two. Special considerations for the nursing home resident. PMID- 6916679 TI - PRN drugs... to give or not to give? PMID- 6916680 TI - The older adult and drug therapy: Part two. Simon Farber, a man on a complex regimen. PMID- 6916681 TI - The older adult and drug therapy: Part two. Thirteen drugs and what they cost. PMID- 6916683 TI - 70+ and going strong. Roleless in retirement--not Lulu. Interview by G. Maureen Chaisson. PMID- 6916685 TI - Geriatric nurses assess their educational needs. PMID- 6916682 TI - Nutrition: taste, smell, and appetite--they go together. PMID- 6916684 TI - A 10-week exercise program for senior citizens. PMID- 6916686 TI - A pet show for remotivation. PMID- 6916687 TI - Life satisfaction among nursing home residents. PMID- 6916688 TI - The Congressional Senior Intern Program. PMID- 6916689 TI - "You're a what? What's a Dolphin?". PMID- 6916690 TI - Drugs and the elderly. Dry mouth--causes and cures. PMID- 6916691 TI - Nutrition. Are "health" foods healthier? PMID- 6916692 TI - 70+ and going strong. A lifelong learner. PMID- 6916694 TI - [Changes in the drug resistance of bacteria from peripheral infections after 5 years]. AB - The reports of outpatients with surgical infections of the years 1972 and 1977 are compared to demonstrate changes in composition of the spectrum and resistance to antibiotics. In the first period 425 cases could be used for study, in the second only 132 cases could be traced. In the second period phlegmonous infections, caused by streptococci were twice as frequent as in 1972. In the same year resistance of staphylococci to Penicillin was found in 43% of the cases. Five years later no more resistance was present and in 28,8% Penicillin even proved to be the most efficient drug. Likewise the streptococci had become more sensitive to Penicillin in the second period, but Cephalosporin remained the treatment of choice for this type of infections. Gram negative germs as B. coli were found much less in 1977 than five years before and their sensibility to sulfamethoxazol-trimethoprim was remarkably higher. The study demonstrates the changes in antibiotic resistance of a given germ population as well as the need for close observation of these changes. Standard antibiotic treatment has to be adapted to the modifications of germ behavior. PMID- 6916693 TI - Osteoporosis. PMID- 6916695 TI - Effect of hog pancreatic kallikrein on blood pressure in rats. AB - In all mammals investigated so far, an amount of 0.1 - 1 biological unit (KU) of hog pancreatic kallikrein per kg body weight injected intravenously caused a fast reduction in blood pressure with one exception, the rat. Even 1000 times higher doses of hog pancreatic kallikrein did not reduce the blood pressure in this animal. In spite of many experiments performed with rats using hog pancreatic kallikrein to influence various metabolic pathways, there has been no proof, to date, that this enzyme also causes kallikrein-specific effects via kinin liberation in rats. We found only a slow and weak reduction of rat blood pressure after injection of 100 KU hog pancreatic kallikrein per rat, when the endogenous kininases had been previously inactivated by the kininase II inhibitor captopril. However, a fast reduction in blood pressure, similar to the response observed after kinin injection, could be recorded if 90 microliter rat blood, previously incubated for a few minutes with a least 20 k.u. hog pancreatic kallikrein in the presence of captopril, was reinjected. Hence, kinin liberation from rat kininogens by hog pancreatic kallikrein does occur, but proceeds so slowly that the fast kinin degradation by kininases can prevent the typical blood pressure effect of kinin in vivo. PMID- 6916696 TI - Genetic variants of human C3 and properdin factor B in a population from Tunisia. PMID- 6916698 TI - Properdin factor B polymorphism in Portugal. AB - The distribution of properdin factor B (Bf) phenotypes and the corresponding gene frequencies in a population sample from Portugal was investigated by agarose-gel electrophoresis and immunofixation. The following gene frequencies were found in Portugal: BfS = 0.6535, BfF = 0.2775, BfS0.7 = 0.0263, and BfF1 = 0.0427. PMID- 6916697 TI - Human properdin factor B: gene frequency study in an African Negroid population (Niger). PMID- 6916701 TI - Breakthrough to nursing: caring through understanding. Part II: folk medicine in the Hispanic population. PMID- 6916700 TI - Nurses and politics. PMID- 6916699 TI - On continuing education. PMID- 6916702 TI - How to plan your finances. PMID- 6916703 TI - Elder abuse. PMID- 6916704 TI - Avoiding malpractice suits. PMID- 6916706 TI - Rite of passage. PMID- 6916707 TI - When medicine isn't what it's "quacked" up to be. PMID- 6916705 TI - His name was Eli Kahn. PMID- 6916708 TI - At last I cry. PMID- 6916709 TI - Choices. PMID- 6916710 TI - The activation of the alternative pathway C3 convertase by human plasma kallikrein. AB - Human plasma kallikrein can replace factor D for the activation of the alternative pathway C3 convertase of human complement. The factor B cleavage patterns by factor D and kallikrein are indistinguishable. The ability of kallikrein to cleave factor B is influenced by the magnesium ion concentration and the C3b concentration. Factor D is about ten-fold more effective on a molar basis, for the alternative pathway C3 convertase activation than is kallikrein. The physiological role of the action of kallikrein on the alternative pathway C3 convertase is discussed. PMID- 6916714 TI - [Psychiatric nursing. Law of 30 June 1838--2]. PMID- 6916713 TI - [Alcohol and pregnancy ... alcohol and the child]. PMID- 6916712 TI - [School health 1982: control, education, prevention and health research]. PMID- 6916715 TI - [Polyneuritis]. PMID- 6916711 TI - Anomalous response of urinary kallikrein to deoxycorticosterone in Dahl salt sensitive rats. AB - Previous evidence shows that salt-sensitive (S) rats have a net increase in plasma mineralocorticoid activity due to 18-hydroxy-11-deoxycorticosterone and decreased urinary kallikrein excretion compared to salt-resistant (R) rats. Since mineralocorticoids stimulate urinary kallikrein excretion, these results are inconsistent. This inconsistency was explained by the fact that, while R rats responded normally to treatment with deoxycorticosterone (DOC) by an increase in urinary kallikrein excretion, S rats showed no change in urinary kallikrein even when treated with 10 mg of DOC/day for 24 days. S and R rats responded identically to DOC with changes muscle electrolytes and relative hypertrophy of the renal distal tubule. Other measures of chronic mineralocorticoid response in S rats beside kallikrein were, therefore, intact. It was found that S rats were capable of responding to Na deficient diet with an increase in urinary kallikrein comparable to R rats. It was argued, therefore, that mineralocorticoid receptor mechanisms and distal-tubular cell responsiveness are intact in S rats. Mild glomerular and tubular scarring was found in S rats and the severity of renal lesions was increased by DOC treatment in S rats. These lesions correlated well with blood pressure and proteinuria. No such lesions were present in control or DOC treated R rats. It was suggested that failure of urinary kallikrein to respond to DOC in S rats may be a secondary phenomenon resulting from renal damage. PMID- 6916716 TI - [Fibrorectosigmoidoscopy]. PMID- 6916718 TI - [Ergonomic approach to school activities: from the idea to the concept and the reality of school ergonomics]. PMID- 6916717 TI - [Nurses faced with the problems of prostitution. Prostitution, public health and reinsertion]. PMID- 6916720 TI - [Parent aggression in a general pediatric service or the "syndrome of aggressed personnel"]. PMID- 6916719 TI - [Alopecia]. PMID- 6916721 TI - [Keeping the elderly at home: a question of ideology]. PMID- 6916723 TI - [Aging of audition (2). Auditory aids]. PMID- 6916722 TI - [Perception of the coronary patient in intensive care]. PMID- 6916724 TI - [The pregnant adolescent]. PMID- 6916725 TI - Circulating levels of prekallikrein and kallikrein in pregnancy and labor. AB - Plasma levels of prekallikrein and kallikrein were measured in 147 pregnant women by the chromogenic substrate S2302 method. At the same time, individual fibrinolytic inhibitors (alpha 2-plasmin inhibitor, alpha 1-antitrypsin, alpha 2 macroglobulin, antithrombin-III, and Cl-inactivator) were determined by the radial immunodiffusion method. The plasma levels of prekallikrein increased significantly during pregnancy and thereafter decreased during delivery. In patients with severe toxemia of pregnancy and hydatidiform mole, plasma prekallikrein levels were low, below the normal range. On the other hand, plasma kallikrein concentrations were within non-pregnant levels until the end of pregnancy, but the levels increased just before delivery. Although no significant correlation was found between prekallikrein levels and fibrinolytic inhibitory activity in pregnancy, Cl-inactivator concentrations tended to be low only when the prekallikrein level was high. These changes in the prekallikrein-kallikrein system in late pregnancy may be related to activation of the kinin, which results in labor pain. PMID- 6916726 TI - Frontiers of nursing in the 21st century: lessons from the past and present for future directions in nursing education. PMID- 6916727 TI - Innovation, change, decision-making, and the key variables in nursing curriculum implementation. PMID- 6916728 TI - Effects of nursing education on attitudes of nursing students toward dying patients in the Nigerian sociocultural environment. PMID- 6916729 TI - The family of the emergency room patient as seen through the eyes of the nurse. PMID- 6916730 TI - How nursing and the community can benefit from nursing research. PMID- 6916731 TI - Learned helplessness among the institutionalized elderly: a pilot study. PMID- 6916732 TI - Medication compliance among discharged psychiatric patients. PMID- 6916733 TI - Theoretical basis for the practice of community mental health nursing. PMID- 6916735 TI - Preventing injuries inflicted on elderly psychiatric patients. PMID- 6916734 TI - Situational anxiety levels and the intensive care unit staff nurse. PMID- 6916736 TI - Assertiveness and post-divorce adjustment in women. PMID- 6916738 TI - National Health Service restructuring: risks and prospects. PMID- 6916737 TI - Relationships among marital adjustment, chest pain, and anxiety in myocardial infarction patients. PMID- 6916739 TI - Fluoride tablet distribution from maternal and child health centres: a feasibility study. PMID- 6916740 TI - The importance of diagnosing premenstrual syndrome. PMID- 6916741 TI - Nits, scabies and an awful mistake. PMID- 6916743 TI - Health visitors, stress and non-accidental injury to children. PMID- 6916742 TI - The International Code on breast milk substitutes. PMID- 6916744 TI - Slimming groups--are they worth your effort? PMID- 6916745 TI - Evaluation of a slimming group. PMID- 6916746 TI - A comparison of hearing test techniques at a well baby clinic. PMID- 6916747 TI - Cardiovascular infections in critical care medicine: overview. PMID- 6916748 TI - Infections associated with intra-arterial lines. PMID- 6916749 TI - Infections of prosthetic cardiac valves and arterial grafts. PMID- 6916750 TI - Infections of permanent transvenous and epicardial pacemakers in adults. PMID- 6916751 TI - Survey of critical care nursing practice. Part III. Responsibilities of intensive care unit staff. PMID- 6916752 TI - Pressures associated with chest tube stripping. PMID- 6916753 TI - Besides the liver, what does the virus of hepatitis attack? AB - I have reviewed some of the clinical and pathogenetic features of the extrahepatic syndromes of viral hepatitis B. They are important for three reasons: First, it is important to be able to reassure the patient with acute viral hepatitis that the troubling symptoms which he frequently fears are due to rheumatoid arthritis, are self-limited, are benign, and will disappear. Second, these syndromes will occur with occult liver disease or with no active liver disease. Frequently, patients will consult a dermatologist for a rash or a rheumatologist for arthritis. They will see a clinical immunologist for a severe vasculitis or a nephrologist for nephritis. They will have no apparent evidence of liver disease, and the etiologic agent will not be discovered unless it is searched for, that is, unless one is aware that an occult infection with the hepatitis B virus can cause these syndromes. The third important reason is that all of these syndromes previously have been thought to be idiopathic; several of them have been rather severe and even fatal. Now, with the advent of potential antiviral therapy for viral hepatitis, it becomes important to make a correct diagnosis because now, for the first time, one can think about antiviral therapy for some of these serious syndromes. PMID- 6916754 TI - A study in atrial fusion. PMID- 6916756 TI - Risk factors in coronary artery disease. PMID- 6916755 TI - A complication of myocardial infarction usually requiring surgical intervention. AB - Rupture of the interventricular septum is uncommon (2%), but a very serious complication of an acute myocardial infarction. The septum receives most of its blood supply from the left anterior descending artery and from the posterior descending branch of the right coronary artery. Perforation of the septum occurs in patients with significant disease of both coronary arteries. The prognosis of this complication with medical therapy is poor. There is an 80% mortality rate in the first few days after septal perforation if surgical repair is not attempted. Early diagnosis of ventricular septal rupture complicating an acute myocardial infarction is possible if physical findings are carefully evaluated at frequent intervals. Acute mitral valve pathology and right ventricular infarction can be ruled out by performing right ventricular catheterization to determine intracardiac pressures and oxygen saturations. The echocardiogram is an additional aid in the differential diagnosis. PMID- 6916758 TI - Multiple systems failure. PMID- 6916757 TI - Rehabilitation of patients after acute myocardial infarction. PMID- 6916759 TI - [Women's attitude to the gynecological examination]. PMID- 6916762 TI - [Giving birth to a child on all fours]. PMID- 6916761 TI - [Comprehensive care of mother and infant in relation to prenatal care, delivery and postnatal care in England]. PMID- 6916764 TI - [Suburban child health services for immigrant families]. PMID- 6916763 TI - [Can a gynecologic examination be made into a positive experience?]. PMID- 6916760 TI - [Study tour of India]. PMID- 6916765 TI - [Midwifery education and professional function in various countries]. PMID- 6916766 TI - [Midwives as counselors]. PMID- 6916767 TI - Effect of elastase or histamine on single-breath N2 washouts in the rat. AB - A method for performing single-breath N2 washouts (SBNW) in rats was developed and the test's usefulness was studied using two experimentally induced models of lung disease. Rats were anesthetized, intubated with oral tracheal and esophageal catheters, and tested by plethysmography. The SBNW expirogram was recorded during exhalation after inhaling 100% O2 from residual volume. The slope of phase III (slope III), closing volume (CV), and closing capacity (CC) were calculated. Changes in the SBNW expirogram were compared with changes in breathing pattern, dynamic and quasistatic lung mechanics, lung volumes, and forced expiratory indices. Pre- and postinstillation tests were performed on rats treated with elastase or histamine and on untreated controls. The SBNW indices were altered at significant levels equal to those of other indices of lung function, and different patterns of change were induced by the two disease models. Elastase increased CV and CC, but slope III was unchanged. Other tests suggested loss of elastic recoil and expiratory flow limitation. Histamine increased slope III, but CV and CC were unchanged. Other tests suggested large airway constriction. These results suggested the usefulness of the SBNW in rats, but the relationships between SBNW changes and underlying physiological phenomena remain to be defined. PMID- 6916768 TI - The aminoacyl-tRNA population of human reticulocytes. AB - The aminoacyl-tRNA population of human reticulocytes has been examined. These studies include: 1) determination of the levels of amino acid acceptance for 20 aminoacyl-tRNAs; 2) comparison of 20 aminoacyl-tRNAs from human reticulocytes to those of rabbit reticulocytes by reverse phase chromatography; 3) comparison of the levels of Ile- and Leu-tRNAs in fetal and adult reticulocytes; and 4) determination of the codon recognition properties of human Ala-, Asn-, His-, Leu , Thr-, and Val-tRNAs. These studies provide evidence that the aminoacyl-tRNA population of human reticulocytes is adapted to the requirements of protein synthesis. PMID- 6916769 TI - Leukocyte elastase release during blood coagulation. A potential mechanism for activation of the alternative fibrinolytic pathway. AB - Immunological detection of elastase, an enzyme present within leukocyte granules, has been used as a marker for polymorphonuclear leukocyte activation. Polymorphonuclear leukocytes contained 4.6 mug/10(7) cells, whereas erythrocytes, mononuclear cells, and platelets contained <1% of this level. In plasma that was separated from blood cells after 1 h at 22 degrees C, the mean level of elastase related antigen in seven normal donors was 25+/-6 ng/ml. This level was unaltered by immediate separation of the plasma from the cells, by inclusion of protease inhibitors, or by anticoagulation of the plasma with either EDTA or acidcitrate dextrose (the level in heparinized plasma was approximately threefold higher). In serum, the level of elastase-related antigen was 288+/-125 ng/ml, representing an 11.5-fold increase above plasma levels. The antigen detected in serum was immunochemically indistinguishable from the leukocyte enzyme. Release of elastase was observed when isolated polymorphonuclear leukocytes were added to nonanticoagulated platelet-rich or platelet-poor plasma, recalcified plasma, or to serum. Addition of a chelating agent to serum prevented elastase release, but calcium or magnesium did not induce release in the absence of plasma. Coagulation induced by addition of thrombin to plasma also failed to induce release. In whole blood or in anticoagulated plasma reconstituted with polymorphonuclear leukocytes and then recalcified, initial release of elastase occurred concomitantly with or slightly after clotting and reached maximal levels within 20-40 min after clot formation. The data indicates that early events in coagulation or other pathways that occur in parallel with coagulation induce leukocyte release. The release of elastase, a major fibrinolytic protease of leukocytes, from the cells provides a mechanism for this enzyme or other granule proteases to participate in physiological events. PMID- 6916770 TI - Dihydrotestosterone inhibits fetal rabbit pulmonary surfactant production. AB - Males have a higher morbidity and mortality for neonatal respiratory distress syndrome (RDS) than females, and respond less well to hormone therapy designed to prevent RDS by stimulating fetal pulmonary surfactant production. We have shown that male fetuses exhibit delayed production of pulmonary surfactant. We tested the hypothesis that the sex difference in fetal pulmonary surfactant production is under hormonal control. Pulmonary surfactant was measured as the saturated phosphatidylcholine/sphingomyelin ratio (SPC/S) in the lung lavage of fetal rabbits at 26 d gestation. There was an association between the sex of neighboring fetuses and the SPC/S ratio of the female fetuses, such that with one or two male neighbors, respectively, females had decreasing SPC/S ratios (P < 0.05). We injected dihydrotestosterone (DHT) into pregnant does from day 12 through day 26 of gestation in doses of 0.1, 1.0, 10, and 25 mg/d, and measured the SPC/S ratio in fetal lung lavage on day 26. In groups with the normal sex difference in fetal serum androgen levels (controls, 0.1 mg DHT/d) the normal sex difference in the SPC/S ratio was also present (females > males, P = 0.03). In the 1-mg/d group there was no sex difference in androgen levels and the sex difference in the SPC/S ratio was also eliminated as the female values were lowered to the male level. Higher doses of DHT (10, 25 mg/d) further reduced the SPC/S ratios. We injected the anti-androgen Flutamide (25 mg/d) from day 12 through day 26 of gestation. This treatment eliminated the normal sex difference in the lung lavage SPC/S ratio by increasing the male ratios to that of the females. We conclude that androgens inhibit fetal pulmonary surfactant production. An understanding of the mechanism of the sex difference in surfactant production may allow development of therapy that is as effective in males as in females for preventing RDS. PMID- 6916772 TI - Alzheimer's disease: pathology, progression, and nursing process. PMID- 6916771 TI - One woman's story. PMID- 6916773 TI - Reversible causes of dementia: a nursing challenge. PMID- 6916775 TI - Prevalence of confusion in elderly hospitalized patients. PMID- 6916774 TI - Helping families of patients with Alzheimer's disease. PMID- 6916778 TI - Management and modes of thought. PMID- 6916776 TI - Properdin factor B polymorphism in Black Americans. AB - Properdin factor B is a genetically-controlled polymorphism that can be demonstrated by agarose gel electrophoresis. The Bf gene frequencies were determined for 194 blacks from the south-eastern United States. The frequencies for Bf-F, Bf-S, Bf-F1, and Bf-S1 are 0.626, 0.034, and 0.013, respectively. The south-eastern blacks have similar Bf frequencies to the South African blacks; however, both these groups are different from blacks from Boston. The frequency differences between south-eastern blacks and Boston blacks may be due to racial admixture differences found in the two populations. PMID- 6916777 TI - Establishing the psychiatric liaison nurse role: collaboration with the nurse administrator. AB - By helping patients, families, the hospital staff deal with the emotional effects of illness, the psychiatric liaison nurse plays a significant role in patients' healing. Since this type of role may be new to the organization, the psychiatric nurse and the nursing administrator must work in tandem to ensure successful role development and entry into the hospital system, both of which are crucial to the effectiveness of the liaison nurse. In our clinical experience, these issues need careful consideration and attention by both nurse administrators and psychiatric liaison nurses. We have attempted to provide practical considerations for facilitating the success of a psychiatric liaison nurse in the hospital system and justifying the value of this role. PMID- 6916780 TI - Factors affecting nurse supply and demand: an exploration. PMID- 6916779 TI - The motivating potential in nursing specialties. PMID- 6916781 TI - The research design. AB - Research design is the plan, structure, and strategy of investigation for answering the research question. The correct design helps isolate items of concern so that they can be examined under known conditions; it eliminates bias and reduces the margin of error, enabling the researcher to state confidently conclusions on which to base future decisions and research. Regardless of the type of research proposed, following a logical plan, such as we have described here, provides the framework for an effective study. The results of well-planned research are contributions to the growing body of nursing knowledge. PMID- 6916782 TI - Helping your staff address ethical dilemmas. PMID- 6916784 TI - The environment of decision. PMID- 6916783 TI - Job expectations of senior nursing students. PMID- 6916786 TI - Nurse staffing in a decentralized organization: Part I. PMID- 6916785 TI - Reading a research article. PMID- 6916789 TI - Calcium antagonists a new antiarrhythmic agent: verapamil. PMID- 6916788 TI - Effects of vanadate on organic ion accumulation in rat renal cortical slices. AB - Sodium vanadate is a potent inhibitor of Na-K-adenosine triphosphatase. p Aminohippurate (PAH) and tetraethylammonium accumulation in rat renal cortical slices was inhibited by vanadate in a dose-dependent manner at medium vanadate concentrations from 10(-6) to 10(-3) M. Inhibition was reversible at vanadate concentrations less than 1.5 x 10(-5) M. The slice content of vanadium (7.5-325 micrometer V/g wt. of tissue) was linearly related to medium vanadate concentrations ranging from 10(-5) to 10(-3) M. The ability of slices to generate glucose and ammonia was not impaired by medium vanadate concentrations up to 5 x 10(-4) M, a concentration that maximally inhibited organic ion accumulation. Increasing medium K+ concentrations potentiated vanadate inhibition of PAH accumulation which correlated with inhibition of sodium pump activity, as determined by 42K+ uptake. Intraperitoneal administration of vanadate (1 or 5 mg V/kg) to rats produced a profound diuresis and natriuresis during the 1st hr. Inhibition of PAH accumulation of renal slices from these rats was related to tissue vanadium concentrations. These data suggest that vanadate exerts its action on proximal tubule transport of PAH via inhibition of Na-K-adenosine triphosphatase. PMID- 6916791 TI - Psychiatric nurse associate: a new career. PMID- 6916792 TI - Sexuality and mental health: implications for nursing. PMID- 6916790 TI - Screening for seizures. PMID- 6916787 TI - Human surfactant: a therapeutic trial in premature rabbits. PMID- 6916793 TI - Psychiatric nurse consultation: who calls and why. PMID- 6916794 TI - Structured experiential learning exercises: a facilitation to more effective learning in clinical settings. AB - Structured experiential exercises can help to make students more aware of the learning skills required in each of the four phases of experiential learning. These exercises should be structured to increase the trust and communication between the clinical nursing instructor and the students, as well as to assist the students to understand better their own and others' values and group processes. We believe that exercises that fulfill these objectives enable the students to adjust better to the learning styles required in a clinical course. Moreover, students who obtain increased awareness of their own values and those of others may become more effective members of the nursing profession. PMID- 6916795 TI - Therapeutic role of the legal process. PMID- 6916796 TI - Incest victims and offenders: myths and realities. PMID- 6916797 TI - Concerns of student nurses prior to psychiatric nursing experience: an assessment and intervention technique. PMID- 6916798 TI - Rural community mental health center: adaptation of a conceptual framework. PMID- 6916799 TI - Health locus of control, values, and weight reduction behavior. AB - This study, in a natural setting, attempted to predict health-related behavior on the basis of the personality construct locus of control. Thirty-six participants in a weight reduction program completed the Multidimensional Health Locus of Control Scale (MHLC) and a value scale that included the values of "health" and "physical appearance." Subjects also were asked to determine their weight loss goal in pounds. Three months later their progress was assessed, and 22 of the subjects again completed the MHLC and value surveys. Consistent with the first hypothesis, those subjects who perceived their health status to be under the control of powerful others and valued health and/or physical appearance highly weighed in more frequently at the weight center than did the other subjects. Contrary to the second hypothesis, subjects did not become more "internal" as a result of successful weight loss. Subjects who valued physical appearance highly were found to have higher "external" control beliefs. Theoretical significance and practical applications of the findings are discussed. PMID- 6916800 TI - Withdrawal behavior of schizophrenics: application of Roy's model. PMID- 6916801 TI - Implementation strategies for an inpatient women's support group. AB - The authors believe an inpatient women's group to be a supportive and educative nursing intervention that, when adjunctively combined with other inpatient therapy forms, assists women to resolve sex-role conflicts. Use of the nursing audit, review of relevant literature, development of a group philosophy, objectives, and appropriate credentialing of nurse group facilitators are strategies that maximize group effectiveness. Moreover, group content, which is determined from the client's perspectives of need, and evaluated by behavioral changes among client participants, insures sustained program relevancy. PMID- 6916802 TI - Adolescent female rape victims: special considerations. PMID- 6916804 TI - Women treating women for depression. PMID- 6916803 TI - Help for rape victims through group therapy. PMID- 6916805 TI - Group psychotherapy for depressed women: a model. PMID- 6916807 TI - Adolescent depression: a review of the literature, with implications for nursing care. PMID- 6916806 TI - Role theory and the concept of powerlessness. PMID- 6916808 TI - Familism, machismo and child rearing practices among Mexican Americans. PMID- 6916809 TI - Cross-cultural psychiatry: the applicability of Western Anglo Psychiatry to Asian Americans of Chinese and Japanese ethnicity. PMID- 6916810 TI - Management of the withdrawal syndrome of barbiturates and other central nervous system depressants. PMID- 6916811 TI - Preventing and alleviating staff burnout through a group. PMID- 6916812 TI - Parenting the autistic child. PMID- 6916813 TI - The use of family therapy in terminal illness and death. PMID- 6916814 TI - Father-daughter incest: detection of cases. PMID- 6916815 TI - Major treatment issues and techniques in family therapy with the borderline adolescent. PMID- 6916816 TI - Use and modifications in group psychotherapy with chronic schizophrenic outpatients. AB - The authors have presented a framework for group psychotherapy with chronic schizophrenic outpatients which is based on belief that these patients can engage in moderately intensive insight-oriented therapy. The functional deficits and the interpersonal needs of these patients have been identified, and a strategy of intervention has been developed to ameliorate these deficits and facilitate gratification of these needs. Modifications in traditional group approaches are necessary for these groups to be a success. These include alterations in: 1) the group contract, 2) role and tasks of the therapists, and 3) use of special techniques. The authors believe that use of these techniques, informed by genuine interest in and empathy for these patients, will lead to a successful group experience for all. PMID- 6916818 TI - Group therapy with parolees in a community mental health center. AB - Seeing parolees, who were reluctantly seeking mental health services, in individual therapy was unsatisfactory. Although there were identifiable mental health reasons for their referral, they did not recognize a need for individual therapy. In addition, as the therapist, I felt frustrated, and I lacked empathy. Recognizing a problem, I utilized the nursing process: assessment, planning, implementation, and evaluation, to solve the problem and provide better nursing therapy. A modified self-help group provided support to the parolees to resolve their disequilibrium, to enhance their self-esteem, to teach them to structure their own time and to satisfy the requirements of their paroles. This therapist, as well as the group members and cotherapist, gained personally from the group experience. I developed an awareness of the parolees disequilibrium and I broadened my capacity for empathy. PMID- 6916817 TI - Reminiscing psychotherapy with aging people. AB - Reminiscing is the process of remembering one's past, either verbally or internally. Time and the individual's selective processes influence what it remembered and how the memories are evoked. Although reminiscing starts around age 10 and persists throughout life, when aging people reflect on the past the behavior often is regarded as a sign of increasing mental deterioration. Some older people avoid reflecting on the past to prevent being labeled "senile." However, some clinical investigators have found reminiscing beneficial. In 1963 Butler wrote that the elderly psychiatric patients he observed engaged spontaneously in reminiscing and what he termed the "life review." He assumed the life review to be a normal, developmental phenomenon triggered by the person's realization of impending personal death. Potential benefits included resolution of old conflicts, personality reorganization, and restoration of meaning in the individual's life. Studying reminiscenses of aging persons who came from various settings, clinical investigators examined Butler's original ideas and noted other findings. Descriptions of the memories of older people without psychiatric illness demonstrate that some reminiscing is simple story-telling and glorification of the past in addition to life review. However, most investigators believed that remembering the past helped aging people personally and socially. Relationships between the content of memories and present conflicts were explored, and individual and group therapeutic approaches with aging people were designed to encourage reminiscing. Reminiscence provides unique opportunities for clients and therapists to have positive growth experiences. PMID- 6916819 TI - Transference and countertransference in group therapy settings. PMID- 6916820 TI - What's a medication group? AB - For therapists interested in a didactic model, a Medication Group can be an ideal vehicle for patient education. Our patients are remarkably well informed on dopamine, tardive dyskinesia, side effects, types and levels of drugs, early symptoms, individual stressors and coping mechanisms. They request and titrate drug levels according to their own identification of symptom distress. There is no question that the ability to control their symptoms and medications is a positive and important experience for them. The focus for this paper, however, has been an exploration of a group therapeutic strategy which deals with the phenomenological needs of chronic schizophrenics to address the residual or negative symptoms of schizophrenia, and not their educational needs. PMID- 6916821 TI - The professional support group: a model for psychiatric clinical nurse specialists. AB - In addition to the frustrations experienced by any CNS, the psychiatric CNS in the general hospital setting experiences additional pressures which are inherent to his/her role. The major additional pressure is the great demand for the provision of support to patients, families, and staff. This necessitates a source of support for the psychiatric CNS. In response to this need, a group of psychiatric CNSs from general hospital settings developed and implemented a model for a professional support group. The formation and developmental process of this professional support group was consistent with literature descriptions of both small group and professional support group development. Informal evaluation demonstrated that this professional support group is achieving its purposes, and continues to function as an ongoing group. PMID- 6916822 TI - Grieving the loss of alcohol: a crisis in recovery. PMID- 6916824 TI - Rules of Thumb: Hints for the psychiatric nursing student. AB - The eight "rules of thumb" offered here are representative of numerous more that have been helpful stimulators for psychiatric nursing students. The suggest to the students a consistent approach based upon a rationale and do not encourage rote memorization of techniques. Students are encouraged to critically analyze the reasons and conceptual underpinnings for each encounter they have with patients. The "rules of thumb" encourage this self-exploration and attention to "What is it I'm really asking, or feeling, or thinking?" Only with this sort of continuous evaluation and reassessment can even the most novice of students begin to establish a therapeutic treatment approach with psychiatric patients. PMID- 6916823 TI - My love: the story of an addiction. PMID- 6916826 TI - Psychiatric nurse associate: a new career. PMID- 6916825 TI - Anger in adolescence. PMID- 6916827 TI - The contemporary American family: romanticism vs reality. PMID- 6916829 TI - [Re-evaluation of the class for expectant mothers--re-evaluation of the objectives of the class]. PMID- 6916830 TI - [Re-evaluation of health education of expectant mothers]. PMID- 6916833 TI - [A new class for education of expectant parents--the goal of Ubugoe Kyoshitsu]. PMID- 6916831 TI - [Reconsideration of the class for expectant mothers--a survey by questionnaires issued and collected by the Nakano-Kita Public Health Clinic at Nakano Ward]. PMID- 6916834 TI - [The ideal form of health instructions to be given at discharge: evaluation based on comprehension and the extent of fatigue of the puerperal patients]. PMID- 6916828 TI - [Effect of aging on urinary kallikrein excretion in normal subjects and patients with essential hypertension (author's transl)]. PMID- 6916832 TI - [Re-evaluation of local classes for expectant mothers]. PMID- 6916836 TI - [A class for mothers held at St. Barnabas Hospital]. PMID- 6916837 TI - [Establishment of midwifery profession (1). A reflection on the progress made by the Japanese Nursing Association Midwifery Section]. PMID- 6916838 TI - [A letter from the United States. Postpartum ovarian vein thrombosis]. PMID- 6916835 TI - [Health instruction for mothers given at a private hospital]. PMID- 6916839 TI - [Lamaze delivery at Masaki Midwifery Clinic--a husband's view]. PMID- 6916840 TI - [Breech presentation and CPD (cephalopelvic disproportion)]. PMID- 6916841 TI - [Attitude of instructors in clinical training]. PMID- 6916843 TI - [Search of educational humanity (1). Prologue]. PMID- 6916842 TI - [Study program for the "nursing process of patients with early rupture of the fetal membrane"]. PMID- 6916845 TI - [Simple life in Scotland]. PMID- 6916844 TI - [Unification of the organization of the Japanese Nursing Association and actions of the Public Health Nursing Committee]. PMID- 6916847 TI - [On definition of the needs of an alcoholic patient requiring assistance in his effort in abstention]. PMID- 6916846 TI - [A schizophrenic wife and assistance extended to her family (II)]. PMID- 6916848 TI - [A lesson in handling a case of an autistic child]. PMID- 6916850 TI - [Public health nursing activities and the conditions at Takasu-Machi, Hokkaido]. PMID- 6916851 TI - [Citizens' conception of health problems: on services for citizens. A discussion]. PMID- 6916849 TI - [Planning health instructions for continuing breast feeding]. PMID- 6916852 TI - [Public health nursing: the nurse's role in community-based practice]. PMID- 6916853 TI - [Report of the research group "Operation Family" is published]. PMID- 6916854 TI - [Nursing research in Sweden. Crede's prophylaxis]. PMID- 6916855 TI - [How does it feel to be a father?]. PMID- 6916856 TI - [Gently and naturally - a generous attitude]. PMID- 6916858 TI - [Our concept of humanity and family violence]. PMID- 6916857 TI - [Family violence]. PMID- 6916861 TI - [Reflections of a present-day midwife]. PMID- 6916860 TI - [Alcohol abuse problem and families with children]. PMID- 6916859 TI - [Family violence and the child]. PMID- 6916862 TI - [The Finnish Red Cross in action in Kenya]. PMID- 6916863 TI - [The best for mothers and children]. PMID- 6916864 TI - [The past and the future (Finnish Midwives Association)]. PMID- 6916865 TI - [Gynecological infections and their background]. PMID- 6916866 TI - [The benefits of psychoprophylaxis for labor and childbirth]. PMID- 6916867 TI - [Reevaluation of Crede's prophylaxis]. PMID- 6916868 TI - [Image of the nurse: an analysis of the contents of American nursing journals]. PMID- 6916869 TI - [Nursing in the European Community: Denmark]. PMID- 6916870 TI - [Statistical file. Fluctuations and the current figure of the nursing personnel employed at hospitals]. PMID- 6916871 TI - [Independent nursing practice at an outpatient clinic - a thought on respiratory training]. PMID- 6916873 TI - [Nursing at specialized ambulatory clinics]. PMID- 6916872 TI - [Nursing at an outpatient clinic of a newly established hospital - evaluation of the practice at the new Kobe City Hospital]. PMID- 6916875 TI - [Position of nursing at the outpatient clinic in the framework of health care]. PMID- 6916876 TI - [Nursing and its current status - a lesson from history]. PMID- 6916874 TI - [Nursing accomplishment at the outpatient clinics - a report from a community hospital]. PMID- 6916877 TI - [Development of continuing nursing education in the United States]. PMID- 6916880 TI - [Medical topics: pH of the large intestine]. PMID- 6916878 TI - [Diary of a home-visiting nurse. Suffering of a patient with a refractory neurologic disease and his family]. PMID- 6916879 TI - [A profile of a nurse: Ms. Kimi Fujishiro, the first chief of the Health Promotion Section of Kanagawa Prefecture selected from the nursing profession]. PMID- 6916881 TI - [Medical topics: table salt and the blood pressure]. PMID- 6916882 TI - [Medical topics: viral hemorrhagic fever]. PMID- 6916883 TI - [Nursing in the European Community: Ireland]. PMID- 6916884 TI - [Iatrogenic incidents during multiphasic health screening: responsibilities of the physician and nurse at medical history taking]. PMID- 6916885 TI - [Continuing nursing education in the United States and the problems in Japan]. PMID- 6916886 TI - [Statistical file: age classification of students entering nursing schools]. PMID- 6916887 TI - [Understanding of sex-related problems in humane nursing]. PMID- 6916889 TI - [Nursing education and sex]. PMID- 6916888 TI - [Sex in healthy life: sex in school education]. PMID- 6916891 TI - [Posture and heart rate - with special reference to life activities of patients]. PMID- 6916890 TI - [Nursing and sex. Discussion]. PMID- 6916892 TI - [Clinical training (I) in adult nursing and in internal medicine at a home for the aged requiring special care]. PMID- 6916894 TI - [Medical topics: dumping syndrome]. PMID- 6916893 TI - [Medical topics: brain chemistry in parkinsonism]. PMID- 6916896 TI - [Iatrogen incidents related to nursing. An injection given by a nurse without instructions from the physician]. PMID- 6916895 TI - [Diary of a home-visiting nurse. 7. Problems of urinary and fecal incontinence]. PMID- 6916897 TI - [Primary nursing in day-to-day practice]. PMID- 6916898 TI - [Statistical file. Employment of nursing personnel at hospitals]. PMID- 6916899 TI - [Repeated conferences on a dying patient]. PMID- 6916900 TI - [The effects of case conferences on nursing care]. PMID- 6916901 TI - [Practical conferences: their relationship to the nursing plans and nursing practice]. PMID- 6916904 TI - [Nursing in the European Community: nursing in the Netherlands]. PMID- 6916903 TI - [Position of the case conference in nursing practice]. PMID- 6916902 TI - [Conference: current problems of case conferences. Discussion]. PMID- 6916905 TI - [Profile of a nurse: Ms. Noriko Yuasa who uses the sign language in nursing in a ward and in the community]. PMID- 6916906 TI - [Medical topics. Kawasaki disease]. PMID- 6916907 TI - [Neural tube defect]. PMID- 6916908 TI - Risk assessment: a systematic approach to teenage pregnancy. PMID- 6916909 TI - Meeting needs in Southwest Kansas. PMID- 6916910 TI - Self Rx: hugging. PMID- 6916911 TI - Nursing diagnosis: a term whose time has come. PMID- 6916912 TI - The hospices of Kansas. PMID- 6916913 TI - Autonomy for nurses through business. PMID- 6916914 TI - Eyewitness report: nursing in China. PMID- 6916915 TI - Vanadate inhibits urinary acidification by the turtle bladder. PMID- 6916916 TI - [Use of pancreatin in the treatment of purulent-necrotic ulcers in patients with diabetes mellitus]. PMID- 6916918 TI - [Need of the aged for health: physical health & nursing care]. PMID- 6916917 TI - [Problem of the aged & its action: health care]. PMID- 6916920 TI - [Nurses' role on the welfare of the aged]. PMID- 6916921 TI - [Survey report on nursing education, 1981]. PMID- 6916919 TI - [Need of the aged for health: mental and social health]. PMID- 6916922 TI - [Nursing care for the child who has heart disease]. PMID- 6916923 TI - [Pre-operative nursing care for the child who has heart disease]. PMID- 6916924 TI - [Post-operative nursing care for the child who has heart disease]. PMID- 6916925 TI - [A survey on clinical practice of baccalaureate nursing students]. PMID- 6916926 TI - [A clinical study on the empathy and rapport with negativism in patients]. PMID- 6916928 TI - [Education nursing class; hemodialysis]. PMID- 6916927 TI - [A study on deathbed & death - comparison of clergyman with medical man]. PMID- 6916929 TI - [Problems of the aged & its action: general action]. PMID- 6916930 TI - [Overtaxed superwoman and still an expert. Demands on colleagues in community nursing]. PMID- 6916932 TI - [Nurse with syringe and monkey-wrench. Nurses in Australia take the place of country doctors - the patient is "evacuated"]. PMID- 6916931 TI - [One generation educates the other. Man needs nurturing, forming and educating - directions for intelligence]. PMID- 6916933 TI - [Hyperlipoproteinemia: pathogenesis, risk and therapy]. PMID- 6916934 TI - [Virus pneumonia]. PMID- 6916935 TI - [Perspectives in nursing]. PMID- 6916938 TI - [The psychiatric department in the general hospital]. PMID- 6916939 TI - [Results with the cancer data bank in Munster. Datapoint computer for patient care and medical research]. PMID- 6916937 TI - [Juvenile chronic arthritis]. PMID- 6916936 TI - [On the way in the direction of the patient]. PMID- 6916940 TI - [Scoliosis - clinical aspects and therapy]. PMID- 6916941 TI - [Cervix carcinoma. Clinical aspects, therapy and prognosis]. PMID- 6916943 TI - [The nurse - static pole with humor. On nursing dependency as human relation]. PMID- 6916942 TI - [Patients' residence - a new trend. An alternative between hospital and home]. PMID- 6916944 TI - [What a physician likes. Nursing from the physician's viewpoint]. PMID- 6916945 TI - [What nurses criticize. Nursing from the nurses' viewpoint]. PMID- 6916946 TI - [The glamour and misery of risk factors]. PMID- 6916947 TI - [The power of physicians and their assistants]. PMID- 6916948 TI - [Ethics is once again a subject in the hospital]. PMID- 6916949 TI - [Dialysis treatment of acute kidney failure]. PMID- 6916950 TI - [He shouldn't be there for the patients only. Expectations of nursing administration of the hospital chaplain]. PMID- 6916951 TI - [Did everything and still: guilt feelings. Our relations with the dying - everyone must find the answer himself]. PMID- 6916952 TI - [Terminal care in hospices?]. PMID- 6916953 TI - [A pickle for Woyczek]. PMID- 6916954 TI - What can we expect from school health education? PMID- 6916956 TI - Sports trauma management and the high school nurse. PMID- 6916955 TI - School attendance of children with cancer. PMID- 6916957 TI - Informal provision of school health services by a physician. PMID- 6916958 TI - A survey of health education in Western Kentucky high schools. PMID- 6916959 TI - A closer look at schooling after the first birth. PMID- 6916960 TI - Nurse-role dimensions of a school-based hypertension screening, education, and follow-up program. PMID- 6916961 TI - [Humanistic study of medicine and nursing (2). On wisdom in nursing]. PMID- 6916963 TI - [The nurse: a person within a system. Communication (2). 11. Interpersonal relations and communication in medical practice]. PMID- 6916964 TI - [Future nursing education and curriculum (1). Discussion]. PMID- 6916965 TI - [A trial at continuing nursing in clinical nursing training in internal medicine home nursing by the first class of a junior nursing college]. PMID- 6916966 TI - [Content analysis of a case study of nursing students - use of an objective analysis]. PMID- 6916962 TI - [Bedside conference: planning of clinical training (11). Obstetrical nursing: nursing of postpartum patients (1)]. PMID- 6916968 TI - [Bio-psycho-socio-ethical approaches to terminal patients]. PMID- 6916967 TI - [Care of patients with pain and the use of narcotics as one method--bio-psycho socio-ethical approaches to the terminal patients]. PMID- 6916969 TI - [Study on pain - nursing of a patient in the terminal stage of kidney cancer]. PMID- 6916970 TI - [Significance in preferences and changes of the work schedules of nursing - a study of the work schedule in a nursing unit]. PMID- 6916971 TI - [Use of disposable equipment at municipal hospitals and related problems - survey based on questionnaires sent by the Municipal Hospital Association]. PMID- 6916972 TI - [New development in nursing education. Problem-solving and a learning theory]. PMID- 6916973 TI - [Teaching to promote the desire for learning]. PMID- 6916975 TI - [Current topics in clinical training in nursing: preparation for clinical training and training in the classroom]. PMID- 6916974 TI - [Educational goal in clinical training]. PMID- 6916976 TI - [Current topics in clinical training in nursing. Clinical training at a hospital]. PMID- 6916978 TI - [Current topics in clinical training in nursing. Clinical training in medical education]. PMID- 6916977 TI - [Current topics in clinical training in nursing. Grading in clinical training]. PMID- 6916979 TI - [Humanistic study of medicine and nursing. (3) Between the patient and therapeutic personnel]. PMID- 6916980 TI - [Bedside conference: planning of clinical training (12). Obstetrical nursing: nursing of a postpartum patient (2)]. PMID- 6916981 TI - [Nurse: a person within a system. Communication (3). 12. Communication in a therapeutic scene - a view of a nurse]. PMID- 6916982 TI - [Future nursing education and curriculum (2). Discussion]. PMID- 6916983 TI - [Evaluation of the process of acquiring basic nursing technics after graduation- a survey of nursing graduates]. PMID- 6916984 TI - [Nursing process/nursing of schizophrenic patients. Definition of schizophrenia]. PMID- 6916985 TI - [Nursing process/nursing of schizophrenic patients. Diagnosis and treatment of schizophrenia]. PMID- 6916986 TI - [Nursing process/nursing of schizophrenic patients. Basic nursing of patients with schizophrenia]. PMID- 6916987 TI - [Nursing process/nursing of schizophrenic patients with hebephrenic schizophrenia and clinical cases]. PMID- 6916988 TI - [Nursing process/nursing of schizophrenic patients. Evaluation of the nursing process. Discussion]. PMID- 6916989 TI - [Nursing seminar: prevention of infections (2). Improvement of the environment for prevention of hospital infections]. PMID- 6916991 TI - [Prevention of infections and nursing of leukemic patients in the general ward]. PMID- 6916990 TI - [Practice of prophylaxis of B type hepatitis]. PMID- 6916993 TI - [Nursing and therapy: resuscitation. Cardiac resuscitation: its theory]. PMID- 6916994 TI - [Nursing and therapy: cardiac resuscitation. Practice of cardiac resuscitation and nursing keypoints]. PMID- 6916992 TI - [Nursing process: possibilities and limitations of planned practice. (6). Evaluation of procedure in each process: planning--choice of methods for the solution of the problem]. PMID- 6916995 TI - [Assistance for the patient with liver cancer who is aware of her condition and the response of the nursing personnel]. PMID- 6916996 TI - [In search of new nursing philosophy. XIII. Nursing practice, science, and philosophy]. PMID- 6916997 TI - [Nursing report. Naso-oral suction in premature infants--a method acceptable to the child and not likely to cause apnea or bradycardia]. PMID- 6916999 TI - [Clinical essay. Informing the cancer patient of the nature of his illness]. PMID- 6916998 TI - [Test yourself. Nursing of a child with acute glomerulonephritis]. PMID- 6917000 TI - Cognitive moral development theory and moral decisions in health care. PMID- 6917001 TI - The emerging stowaway: patients' rights in the 1980s. PMID- 6917002 TI - Legal problems of medical practice; withholding treatment from defective newborns. PMID- 6917003 TI - Monograph 11. Self control behaviors of school-age children who are hospitalized for cardiac diagnostic procedures. PMID- 6917004 TI - [Diabetic polyneuropathy]. PMID- 6917006 TI - [Mental disorders in cardiospasm]. PMID- 6917005 TI - [Depressions in old age]. PMID- 6917010 TI - [Treatment of schizophrenia]. PMID- 6917007 TI - [Study of emotions in the nurse's practice]. PMID- 6917008 TI - [Psychological aspects of working with patients]. PMID- 6917009 TI - [Characteristics of the beginning of schizophrenia]. PMID- 6917011 TI - [Amyotrophic lateral sclerosis]. PMID- 6917012 TI - [Hyperbaric oxygenation in the psychiatric clinic]. PMID- 6917013 TI - [Diagnosis and treatment of acute craniocerebral trauma received during a state of alcoholic intoxication]. PMID- 6917014 TI - [Role of the nurse in the system of rehabilitative measures]. PMID- 6917015 TI - [Care of patients with disordered mental functions]. PMID- 6917016 TI - [Nurse's work in the open-door psychiatric ward]. PMID- 6917017 TI - [Psychotherapeutic work of the nurse in work therapy shops]. PMID- 6917018 TI - [Premature infant. IV. Feeding of premature infants]. PMID- 6917020 TI - [Deontology for nurses in the neurological department]. PMID- 6917019 TI - [Task in neurology]. PMID- 6917021 TI - [Circulatory disturbance encephalopathy]. PMID- 6917022 TI - Today's creativity - tomorrow's reality. PMID- 6917024 TI - Meet the dawn. PMID- 6917023 TI - Restricted resources ahead: a test for nursing creativity. PMID- 6917025 TI - Power through self awareness. PMID- 6917026 TI - Are your educational expenses tax deductible? PMID- 6917027 TI - Power through self awareness. PMID- 6917029 TI - "I will join you if" (on belonging to a professional organisation): Inaugural Rosalind Paget Memorial Lecture. PMID- 6917028 TI - The RCM--the first 100 years: what are our opportunities? PMID- 6917030 TI - Low birth weights throughout the world. PMID- 6917031 TI - Consultation papers from the United Kingdom Central Council for Nursing, Midwifery and Health Visiting. No. 3: Standing & joint committees. PMID- 6917032 TI - Consultation papers form the United Kingdom Central Council for Nursing, Midwifery and Health Visiting. No. 4: Education & training - the development of nurse education. PMID- 6917033 TI - The RCM - the first 100 years: what are our opportunities? The personal & professional development of the midwife. PMID- 6917035 TI - Antenatal education - does it work? PMID- 6917034 TI - Sleep in the puerperium. PMID- 6917037 TI - Through the forest. Out of the wood? PMID- 6917036 TI - Theatre nursing in Europe NATN/Surgikos Fellowship Paper 1980-81. PMID- 6917039 TI - Ostomists: a world of difference. PMID- 6917040 TI - Theatre nursing in Europe. PMID- 6917038 TI - The role of the theatre nurse within the surgical unit. PMID- 6917042 TI - Epidemiology and prevention. AB - Any national strategy of preventing disease and promoting health cannot ignore the implications of social deprivation. As social policy moves away from principles of universal provision and towards greater selectivity, there will be an onus on epidemiology to help identify those who are vulnerable--economically, chemically, and environmentally, as well as biologically. The uncertainty of current knowledge about lifestyles calls for new experiments, not merely observation and disputation. PMID- 6917041 TI - A study of elastase peptides from bovine white matter proteolipid. AB - Bovine white matter proteolipid has been digested with elastase in the presence of deoxycholate. After acidification, the digest was separated into an acid soluble and an acid-insoluble fraction. The acid-insoluble fraction was enriched in nonpolar amino acids and, by a combination of solvent fractionation and chromatography, a fraction was obtained which consisted of a mixture of two peptides with a molecular weight of approximately 4000 daltons. The acid-soluble peptides were separated by molecular sieve, ion exchange and high performance liquid chromatography (HPLC) in the reverse phase mode. The purified peptides were smaller than expected on the basis of their elution position from a molecular sieve column, suggesting they were in an aggregated state during the initial chromatography. Reverse phase HPLC was shown to be useful for fingerprinting these peptide mixtures. The data demonstrate the difficulties associated with the study of this proteolipid and emphasize the tendency of both the protein and the peptides derived from it to aggregate. PMID- 6917043 TI - The effect of medical institutions on doctor-patient interaction in Costa Rica. AB - The nature and quality of interaction and communication between doctor and patient is an important determinant in adequacy of health care. But patient behavior and physician performance are themselves influenced by the institutional and political setting. Study of two Costan Rican medical care systems reveals how historical differences in ideology and expectation can shape institutions and their services. PMID- 6917044 TI - Use of health services by the elderly in low-income communities. AB - Although it is generally assumed that there has been a narrowing of the gap in health care between poor and nonpoor families, the relative contributions of improved fiscal and geographic access are not well documented. Almost 2,000 elderly poor persons were studied to examine factors affecting their use of health services. A number of personal and structural problems are identified when cultural and ethnic backgrounds are considered. PMID- 6917046 TI - Introduction to CDC's guidelines for prevention of intravascular infections. PMID- 6917047 TI - Patterns for effective nursing action within health bureaucracies. PMID- 6917045 TI - The National Intravenous Therapy Association, Inc.: outline for standards. PMID- 6917048 TI - The lecture approach to teaching nursing -- method or habit? PMID- 6917050 TI - Development of a primary care setting for nursing education. PMID- 6917049 TI - A faculty learns about rural nursing. PMID- 6917051 TI - Yearly review of salaries in home health agencies and community health services- 1981. PMID- 6917052 TI - The season for collective bargaining. PMID- 6917053 TI - Collective bargaining and professionalism: incompatible ideologies? PMID- 6917054 TI - Collective bargaining as a power resource for professional goals. PMID- 6917055 TI - Mini on the scene: Seattle, Washington. The 1976 Seattle nurses' strike. PMID- 6917056 TI - Mini on the scene: Seattle, Washington. Role of the nurse administrator in labor negotiations. PMID- 6917057 TI - Mini on the scene: Seattle, Washington. Agency shop and the nurse administrator. PMID- 6917058 TI - Collective bargaining and the road to self-determination. PMID- 6917059 TI - Conflicting loyalties of the nurse. PMID- 6917060 TI - Nursing administration and undivided loyalty. PMID- 6917061 TI - Breaking a union organizing effort--a rural hospital's experience. PMID- 6917062 TI - An alternative to collective bargaining. PMID- 6917063 TI - Collective bargaining: a means of conflict resolution. PMID- 6917064 TI - A first-hand view of the unit teacher role. PMID- 6917065 TI - Assessing need and feasibility for an outreach baccalaureate program for RNs. PMID- 6917066 TI - Nursing students experiment with reality. PMID- 6917067 TI - Meeting the needs of inservice educators. PMID- 6917068 TI - Why a nurse in personnel? PMID- 6917070 TI - Legal notes: memorials for the dead. PMID- 6917069 TI - The role of the nursing officer 2. PMID- 6917071 TI - Personnel management and the nurse. PMID- 6917072 TI - Reviewing performance in the reorganised National Health Service. PMID- 6917073 TI - The management of clinical specialties: 1. Oncology. PMID- 6917074 TI - Self-care for nurses: assertiveness. PMID- 6917075 TI - Art and science of management: Shift rotation--a nursing challenge. PMID- 6917076 TI - Quality assurance & nursing audit: are they effective? PMID- 6917078 TI - Games & simulations. PMID- 6917077 TI - Data processing in staff development. PMID- 6917079 TI - A permanent day shift for staff. PMID- 6917080 TI - Preventing group burnout. PMID- 6917081 TI - Commitment to nursing & to self. PMID- 6917083 TI - Staffing: what the books don't tell you! PMID- 6917082 TI - Law for the nurse manager: students' unsatisfactory clinical performance. PMID- 6917085 TI - Reasonable resignation.... PMID- 6917084 TI - Role theory: framework for change. PMID- 6917086 TI - The chaplain-nurse relationship. PMID- 6917088 TI - Collaborative practice. PMID- 6917087 TI - Employee discipline: be positive not punitive. PMID- 6917089 TI - Reducing workloads for staff nurses. PMID- 6917090 TI - Art and science of management: your basic resource. PMID- 6917092 TI - Change-over to head nurse. PMID- 6917091 TI - What manual?! Getting policies & procedures on the line. PMID- 6917093 TI - Law for the nurse manager: liability of nurse floated to another unit. PMID- 6917094 TI - Contingency nursing. PMID- 6917095 TI - Political savvy. PMID- 6917098 TI - Rural nursing: a challenge--not for everyone. PMID- 6917097 TI - Nurses leave hospitals for Casino jobs. PMID- 6917096 TI - Providing care and security for America's first in-vitro baby. PMID- 6917101 TI - You can earn CEUs in a remote setting. PMID- 6917099 TI - Rural nursing: the only medical care for miles around. Meet Marion Thornton, RN, FNP. PMID- 6917100 TI - Frontier Nursing Service. A model for rural health care. PMID- 6917102 TI - China is saying "Ni hao!" (Hello). PMID- 6917103 TI - Financial nurse: supply side versus demand side economics. PMID- 6917105 TI - Eye hazards in industry. PMID- 6917104 TI - Nurses' new image. PMID- 6917107 TI - Safety: measure for measure. PMID- 6917106 TI - Cadmium: its uses and processes. PMID- 6917109 TI - Aerobic fitness: how do hospital personnel measure up? PMID- 6917108 TI - Nursing students investigate work-related health needs of Jerusalem construction workers. PMID- 6917110 TI - Industry: a clinical setting for B.S. nursing students. PMID- 6917111 TI - Identifying organizational stressors: the nurse's role. PMID- 6917112 TI - Hazards of a hospital complex: an occupational health screening program. PMID- 6917113 TI - [The suffering person in search of meaning]. PMID- 6917114 TI - [Dental prophylaxis. 3]. PMID- 6917115 TI - [Tasks of the nursing service administrator - an analysis. 1]. PMID- 6917117 TI - [Nursing legislation]. PMID- 6917116 TI - [Inservice education in the Bad Ischl district hospital]. PMID- 6917118 TI - [Health education in nursing]. PMID- 6917119 TI - [Non-compliance--understanding of drugs and correct administration by patients]. PMID- 6917120 TI - [WHO Intermediate Program for Nursing and Midwifery in Europe - introduction of the nursing process in Austria]. PMID- 6917121 TI - Need for graduate education in nursing in Pennsylvania. PMID- 6917122 TI - Analgesic-associated nephropathy: a potential and actual health problem. PMID- 6917123 TI - Voices. PMID- 6917124 TI - Primary health care for Indochinese refugee children. PMID- 6917125 TI - NAPNAP membership survey 1981: PNP salaries, functions and distribution. PMID- 6917127 TI - State certification of the nursing specialties: a new trend in nursing practice law. PMID- 6917126 TI - Childhood urinary tract infection. PMID- 6917129 TI - Pediatric management problems: primary functional enuresis. PMID- 6917130 TI - 20/20 vision screening. PMID- 6917128 TI - Pediatric drug information. What medication do parents need to get up and give their child at night? PMID- 6917131 TI - Chronic headaches in children. PMID- 6917132 TI - Kawasaki disease--would you know it if you saw it? And--what would you do about it? PMID- 6917133 TI - [The university as a socio-historical phenomenon]. PMID- 6917134 TI - [Nursing implications before, during and after blood transfusion]. PMID- 6917135 TI - [Human relations in management]. PMID- 6917139 TI - Analyzing the cost of baccalaureate education. PMID- 6917136 TI - Position statement on educational mobility. PMID- 6917137 TI - Position statement on nursing roles - scope and preparation. PMID- 6917141 TI - Tips that make sense in grantsmanship. PMID- 6917138 TI - The cost components of an instructional program. PMID- 6917140 TI - Comparing and analyzing expenditure factors in nursing education. PMID- 6917142 TI - Who's shaping health care? PMID- 6917143 TI - Nursing practice trends. PMID- 6917144 TI - Hospice--a developing model of care. PMID- 6917145 TI - The changing role of State Boards of Nursing. PMID- 6917146 TI - How you can have a voice--a legislator's view. PMID- 6917147 TI - How to disseminate information. PMID- 6917148 TI - Legal processes that affect health care trends. PMID- 6917149 TI - Changing existing legislation. PMID- 6917151 TI - Radioactivity is good for you! PMID- 6917150 TI - Introducing legislation and seeing it enacted. PMID- 6917152 TI - Who's shaping health care? PMID- 6917154 TI - Impressions of a nurse working in oncology. PMID- 6917153 TI - A strategy for sequence phylogeny research. AB - Minimal mutation trees, and almost minimal trees, are constructed from two data sets, one of phenylalanine tRNA sequences, and the other of 5S RNA sequences, from a diverse range of organisms. The two sets of results are mutually consistent. Trees representing previous evolutionary hypotheses are compared using a total weighted mutational distance criterion. The importance of sequence data from relatively little-studed phylogenetic lines is stressed. A procedure is illustrated which circumvents the computational difficulty of evaluating the astronomically large number of possible trees, without resorting to suboptimal methods. PMID- 6917155 TI - Shining brightly. PMID- 6917157 TI - The children of Blythe Street. PMID- 6917156 TI - Helping nurses to cope with the anger-dismay syndrome. PMID- 6917158 TI - The search committee process. PMID- 6917160 TI - The missing ingredient. PMID- 6917161 TI - On the structure of time with implications for nursing. PMID- 6917159 TI - The search interview. PMID- 6917163 TI - The young adult's perceptions of the effect of congenital heart disease on his life style. PMID- 6917164 TI - The influence of nursing interventions on chest pain. PMID- 6917162 TI - A continuing education workshop on human relations skills. PMID- 6917166 TI - Postcard to a minister. PMID- 6917165 TI - Commonwealth Nurses Federation Supplement. Today's midwife tomorrow. PMID- 6917167 TI - School nurses--the need for a nationally recognized role. PMID- 6917168 TI - A raw deal? Nursing salaries. PMID- 6917169 TI - Small is beautiful. PMID- 6917171 TI - 'Thrown in at the deep end.'. PMID- 6917170 TI - A man's job? PMID- 6917172 TI - Appointing ward staff who can teach. PMID- 6917173 TI - Computers 2. Systems analysis. PMID- 6917174 TI - Infection in hospitals. PMID- 6917176 TI - The nurse-patient relationship--1. PMID- 6917175 TI - Health psychology. PMID- 6917178 TI - Communication skills: purpose, the system and the environment. PMID- 6917177 TI - The Nurses Act 1949. 1. The draft proposals. PMID- 6917179 TI - Timetable for change. PMID- 6917180 TI - A decade of day care. PMID- 6917182 TI - Nursing in Southern Ireland--1. The quiet revolution. PMID- 6917181 TI - No smoke without fire. PMID- 6917183 TI - Paramedics at work--2. Trauma victims. PMID- 6917184 TI - RSCN training in Scotland. PMID- 6917185 TI - Scenes from nursing life. 2. Pride and prejudice. PMID- 6917186 TI - Urinary incontinence: a disposable flannel and wipe for incontinent patients. PMID- 6917187 TI - Urinary incontinence: the female cone - a urine transfer device. PMID- 6917190 TI - Cold comfort. PMID- 6917188 TI - Systems of life No 86. Systems and signs: examination of smelling and seeing - 1. PMID- 6917189 TI - The Nurses Act 1949. 2. Service priorities. PMID- 6917191 TI - Something in the air. PMID- 6917192 TI - Hidden feelings. PMID- 6917193 TI - Cardiac rehabilitation. 1. Long-term management of coronary heart disease in the British Army. PMID- 6917195 TI - Paramedics at work--3. Helicopter rescue. PMID- 6917194 TI - Nursing care study: a patient with myocardial infarction. PMID- 6917196 TI - Nursing in Southern Ireland--2. A powerful voice. PMID- 6917198 TI - Letter from America. PMID- 6917197 TI - Secure environments. PMID- 6917199 TI - A care plan for David. PMID- 6917200 TI - A question of rape. PMID- 6917201 TI - Research in danger. PMID- 6917202 TI - A time for change. PMID- 6917203 TI - An overall view. PMID- 6917204 TI - Nursing care study: partial rupture of the thoracic aorta following a road traffic accident. PMID- 6917205 TI - Nursing in Southern Ireland-3. An air of tranquillity. PMID- 6917208 TI - Clearing the air. PMID- 6917207 TI - Paramedics at work-4. Learning the job. PMID- 6917206 TI - Child death resulting from non-accidental injury: implications for health visitors. PMID- 6917209 TI - A check on a milk bank. PMID- 6917210 TI - The journal of Infection Control Nursing. PMID- 6917211 TI - Sharps and their safe disposal. PMID- 6917212 TI - The research interests of nurse tutor students. PMID- 6917215 TI - A root cause? PMID- 6917214 TI - Nursing personnel: integration or independence? PMID- 6917213 TI - Infection control in the community. PMID- 6917216 TI - Eccentricity. PMID- 6917218 TI - Nursing in Poland - 2. Psychiatric care. PMID- 6917217 TI - Patterns of drug overdose. PMID- 6917219 TI - Nursing in Southern Ireland - 4. Health or hazard. PMID- 6917221 TI - Spinal injuries. PMID- 6917220 TI - Paramedics at work - 5. Heading west. PMID- 6917222 TI - Key issues in nursing practice: ward management-1. PMID- 6917223 TI - A case for concern. PMID- 6917224 TI - Further studies. PMID- 6917225 TI - Unfair to students? PMID- 6917226 TI - The conduction system of the heart. PMID- 6917228 TI - Infective polyneuritis (Guillain-Barre syndrome). PMID- 6917229 TI - Plasma exchange in Guillain-Barre syndrome. PMID- 6917227 TI - Health and safety in NHS premises. PMID- 6917230 TI - Stoma nursing in the 1990s. PMID- 6917232 TI - Paramedics at work--6. Who needs paramedics? PMID- 6917231 TI - Nursing in Poland--3. Caring for the elderly. PMID- 6917233 TI - Grief reaction. PMID- 6917234 TI - Systems of life No 87. Systems and signs: examining the eye - 2. PMID- 6917235 TI - Key issues in nursing practice: ward management-2. PMID- 6917237 TI - Why ECT is an ethical issue. PMID- 6917236 TI - A question of conscience. PMID- 6917238 TI - No place like home? PMID- 6917239 TI - A vital link. PMID- 6917240 TI - Computers. 1. An introduction. PMID- 6917241 TI - The computer in coronary care. PMID- 6917242 TI - Nursing care study: diabetes mellitus. PMID- 6917245 TI - The problem of staying awake. PMID- 6917243 TI - Nursing in Poland--4. Nurse education. PMID- 6917244 TI - The role of the NO: some implications of research. PMID- 6917246 TI - There's no place like home: could you care more? PMID- 6917247 TI - Community forum. 3. Day surgery: back home to nurse. PMID- 6917248 TI - Community forum. 3. Process action man. PMID- 6917250 TI - We need you, Cathy. PMID- 6917249 TI - The way we are (2). PMID- 6917252 TI - Stop smoking: the first puff is the deepest? PMID- 6917251 TI - Primary health care: influence of the environment. PMID- 6917253 TI - Psychogeriatric nursing: making a difference. PMID- 6917254 TI - Students' forum - vital signs. 3. Respiration. PMID- 6917255 TI - Day surgery. 1. Sameday progression. PMID- 6917257 TI - Spiritual needs: 'In sickness, I lack myself'. PMID- 6917256 TI - Day surgery. 2. Theatre in brief. PMID- 6917258 TI - Lower limb amputations: the last resort. PMID- 6917261 TI - Careers - child/adolescent psychiatry: a family affair. PMID- 6917259 TI - Nursing care study - depression: an unhappy ending. PMID- 6917260 TI - Multiple myeloma: suppressing the problem. PMID- 6917262 TI - Three cheers for social workers! PMID- 6917263 TI - Clinical forum 3 - respiratory emergencies. In case of emergency. PMID- 6917264 TI - Clinical forum 3 - respiratory emergencies. Patient observation. PMID- 6917265 TI - Clinical forum 3 - respiratory emergencies. Team spirit. PMID- 6917266 TI - Clinical forum 3 - respiratory emergencies. Don't panic! PMID- 6917267 TI - Clinical forum 3 - respiratory emergencies. Something special. PMID- 6917268 TI - Are we registering correctly? PMID- 6917270 TI - Back to nursing; making a comeback. PMID- 6917269 TI - Centres of excellence. 1. At the heart of the city. PMID- 6917272 TI - Communication: clothes maketh a patient. PMID- 6917271 TI - Community nursing - Anytown anecdotes. 6. Readily acceptable advice. PMID- 6917273 TI - Leadership qualities: rule by example. PMID- 6917274 TI - Premenstrual syndrome: moody blues. PMID- 6917276 TI - Peptic ulcer: moderation in all things. PMID- 6917277 TI - Expression from within. PMID- 6917278 TI - Nursing care study - living with paraplegia: day by day. PMID- 6917275 TI - Bereavement: the time to grieve. PMID- 6917279 TI - Nursing care study - Hodgkin's disease: priorities in a progressive illness. PMID- 6917280 TI - Gynaecological nursing: a fertile field. PMID- 6917283 TI - The way we are. PMID- 6917282 TI - Community forum. 2. Contraception. PMID- 6917284 TI - Adolescent suicide: a cry for help. PMID- 6917281 TI - Just like a daughter. PMID- 6917285 TI - Computer. 2. Monitoring a sick pattern. PMID- 6917286 TI - Are O-levels necessary? More than just a piece of paper. PMID- 6917287 TI - Just a few king words. PMID- 6917288 TI - Spinal injury: nurses matter too. PMID- 6917289 TI - Students' forum - vital signs. 1. Body Temperature. PMID- 6917290 TI - Blindness. 2. In the dark. PMID- 6917291 TI - Nursing care study - hypocalcaemia: mother and child reunion. PMID- 6917292 TI - Biochemistry. 3. A diagnostic yardstick. PMID- 6917294 TI - Clinical forum. 2. Pain. It's what the patient says it is. PMID- 6917293 TI - Careers - cardiothoracic nursing: heart and soul. PMID- 6917296 TI - How to be a failure. PMID- 6917295 TI - Clinical forum. 2. Pain. Give and take. PMID- 6917299 TI - Helping the terminally ill: a job in a million. PMID- 6917298 TI - Community nursing - Anytown anecdotes. 4. The Bush baby dilemma. PMID- 6917297 TI - Nursing overseas: freedom fighting in Eritrea. PMID- 6917300 TI - Occupational health: prevention versus cure. PMID- 6917301 TI - Gynaecology: no sex, please, Mrs Smith. PMID- 6917302 TI - Biochemistry. 4. Assessment of thyroid function. PMID- 6917303 TI - Nursing care study--motor neurone disease: a victim of circumstance. PMID- 6917304 TI - Careers - intensive care: one-to-one. PMID- 6917307 TI - The name of the team game. PMID- 6917305 TI - Old attitudes die hard. PMID- 6917306 TI - Psychiatry/mental handicap. Forum 2. Portage in Britain: tailored to suit. PMID- 6917308 TI - Health visiting with the forces. 1. Rock on SSAFA. PMID- 6917309 TI - As fate would have it. PMID- 6917311 TI - Students' forum - vital signs. 2. Pulse taking. PMID- 6917310 TI - Reality orientation: around the corner. PMID- 6917312 TI - Nursing the elderly: "Fell walking'. PMID- 6917313 TI - Nursing the elderly: be prepared. PMID- 6917314 TI - Nursing care study- tracheo-oesophageal fistula: no choking. PMID- 6917316 TI - One stage at a time. PMID- 6917315 TI - Careers - Neurological nursing: on impulse. PMID- 6917317 TI - Education forum 2. Group dynamics: the art of working together. PMID- 6917319 TI - Sticking up for your patient. PMID- 6917318 TI - Education forum 2 - Group dynamics: ten minutes in an air-raid shelter. PMID- 6917320 TI - Midwives' dilemma. PMID- 6917321 TI - A testing time ahead. PMID- 6917322 TI - Issues in nursing. 3. Defining the indefinable. PMID- 6917324 TI - New approach: blast your way in with visual dynamite! PMID- 6917325 TI - Health visiting with the Forces. 2. To serve them all their days. PMID- 6917326 TI - Community nursing - Anytown anecdotes. 5. Beneath the surface. PMID- 6917327 TI - Ischaemic leg: a case for critical selection. PMID- 6917323 TI - Issues in nursing. 3. The recognition battle. PMID- 6917330 TI - Time of crisis in Poland. PMID- 6917329 TI - Careers - renal nursing: kidney success. PMID- 6917328 TI - Nursing care study - geriatrics: the last days of May. PMID- 6917331 TI - Hip fractures: special considerations for the elderly patient. PMID- 6917333 TI - Glossary of research terminology. PMID- 6917332 TI - The relationship between urinary retention, multiple straight catheterization, and the incidence of urinary tract infection in the female adolescent following a posterior spinal fusion. PMID- 6917335 TI - Morton's neuroma. PMID- 6917334 TI - Interpreting the results of research. PMID- 6917337 TI - Musculoskeletal assessment: neurovascular examination of the injured extremity. PMID- 6917338 TI - Professional development: writing that article. PMID- 6917339 TI - [Role of the blood kallikrein-kinin system in activating hemodynamic effects induced by L-thyroxine]. AB - Intravenous injection of large L-thyroxine doses (200 micrograms/100 g) was shown to activate kinin formation and to reduce arterial pressure by 33% in experimental white rats. It was established that sensitivity of bradykinin receptors increases during experimental thyrotoxicosis. During kininogenesis inhibition with contrykal, a kallikrein inhibitor, as well as during the kinin system components deficiency, intravenous injection of the same thyroxine doses did not result in arterial pressure changes. The results obtained suggest that hypotensive effect of thyroxine is mediated via the kallikrein kinin system. PMID- 6917341 TI - National development plan. PMID- 6917336 TI - An outsider's insights. PMID- 6917340 TI - Trends in health services development in countries of the Western Pacific region. PMID- 6917342 TI - Health for all Filipinos by 2000. PMID- 6917345 TI - [Rheumatoid polyarthritis]. PMID- 6917344 TI - Primary health care: Philippine policy paper. PMID- 6917346 TI - [Nurses and the patient with rheumatoid polyarthritis]. PMID- 6917343 TI - Primary health care. PMID- 6917347 TI - [Hospital hygiene in progress]. PMID- 6917349 TI - [Treatment of patients with hemorrhoids]. PMID- 6917348 TI - [Vascular studies using Doppler ultrasonic velocimetry and debitmetry]. PMID- 6917350 TI - [Technique: peritoneal puncture-lavage]. PMID- 6917351 TI - [Abdominal contusions and wounds]. PMID- 6917352 TI - [Nursing care in pleural drainage]. PMID- 6917353 TI - [Biological basis of aggression]. PMID- 6917354 TI - [Spontaneous micturition in gynecologic patients with urinary retention. Application of a cooling and brushing method]. PMID- 6917355 TI - [Aspects of nursing research]. PMID- 6917356 TI - [Health for all and the role of nursing in the health services]. PMID- 6917357 TI - [Primary health care in the child health field]. PMID- 6917358 TI - [Homeopathy: an alternative therapy]. PMID- 6917360 TI - The 'joy' of telling a physician he's wrong. PMID- 6917359 TI - A hassle free guide to suctioning a tracheostomy. PMID- 6917361 TI - Cardiogenic shock: help break the vicious circle. PMID- 6917362 TI - Confessions: the unasked question. PMID- 6917363 TI - Gunshot victims. PMID- 6917365 TI - The fine art of giving a physical: examining the nose. PMID- 6917366 TI - Test yourself: dysrhythmia of the month club: is this post-MI dysrhythmia dangerous? PMID- 6917364 TI - Clinical controversies: can we really trust those I & Os? PMID- 6917368 TI - When patient preparation is the key to success. In barium enemas and small bowel studies, timely prep is the decisive factor. PMID- 6917367 TI - An experienced investigator reveals drug diversion tip-offs. PMID- 6917370 TI - Legally speaking. The nurse as expert witness: are you ready? PMID- 6917369 TI - Special report: new drug breakthroughs of 1981, part 2. PMID- 6917371 TI - Sound off! Nurses' needs ignored...in hospitals, and in CE, too. PMID- 6917373 TI - Rights and obligations balance out to keep society running. PMID- 6917372 TI - Leadership at work. She who hesitates to delegate is lost. PMID- 6917374 TI - [Anxiety of the liberal sector]. PMID- 6917375 TI - [Nurse from a strange world]. PMID- 6917376 TI - [White hands and disposable sterile gloves]. PMID- 6917378 TI - [Nurses faced with death and the dying]. PMID- 6917379 TI - [Health care protocol for better health care]. PMID- 6917380 TI - [Skull injuries]. PMID- 6917381 TI - [Neurosurgical disorders]. PMID- 6917382 TI - [Intra-cranial arterial aneurysms]. PMID- 6917377 TI - [Nurses and the wind]. PMID- 6917383 TI - [Brain abscess]. PMID- 6917384 TI - [Anatomy of the brain]. PMID- 6917386 TI - [General concepts of cerebral tumors]. PMID- 6917385 TI - [Patient education. Pedagogic role of the nurse in bladder reeducation in paraplegics and tetraplegics]. PMID- 6917387 TI - [Normal puberty in boys]. PMID- 6917388 TI - [Methods of evaluating stages of puberty]. PMID- 6917389 TI - [An important time of life]. PMID- 6917392 TI - [Normal puberty--physiology]. PMID- 6917390 TI - [Methods of exploring puberty and its' anomalies]. PMID- 6917391 TI - [Delayed puberty]. PMID- 6917394 TI - [Psychological aspects of puberty]. PMID- 6917393 TI - [Precocious puberty]. PMID- 6917395 TI - [Precocious puberty in a girl: role of the nurse]. PMID- 6917398 TI - [Crisis in obstetrics]. PMID- 6917396 TI - [Glimpses of public health in China]. PMID- 6917397 TI - [Normal puberty in girls]. PMID- 6917399 TI - [Monitoring childbirth in a university hospital center. A necessary, but not ineluctable, evil]. PMID- 6917400 TI - [Labor in 1982]. PMID- 6917401 TI - [Case report: labor of Mrs. J...]. PMID- 6917402 TI - [Pre-par]. PMID- 6917403 TI - [Current status of pediatric nurses]. PMID- 6917404 TI - [A welcoming center for sharing a special moment with one's young child children]. PMID- 6917405 TI - [Paradoxal communication]. PMID- 6917407 TI - [Communication is a necessity for everyone]. PMID- 6917406 TI - [Transactions]. PMID- 6917409 TI - [Language, information and communication]. PMID- 6917408 TI - [Psychotherapy and language]. PMID- 6917410 TI - [Psychotherapy and communication]. PMID- 6917411 TI - [From the function of psychiatric nurse to the concept of therapeutic institutions]. PMID- 6917412 TI - [A therapeutic project, what is it? "How training in a psychiatric department was an attempt to find answers..."]. PMID- 6917413 TI - [Millions of people drive under the influence of medicinal drugs]. PMID- 6917414 TI - [Communication and society]. PMID- 6917415 TI - [Psychotherapy and schizophrenia. A few reflexions on family structure]. PMID- 6917416 TI - [Schizophrenia today]. PMID- 6917418 TI - [Institutional therapy and schizophrenia]. PMID- 6917417 TI - [Schizophrenia and family therapy]. PMID- 6917420 TI - [How I see schizophrenia]. PMID- 6917419 TI - [Genetics and schizophrenia]. PMID- 6917421 TI - [The problem of schizophrenia and transcultural aspects of psychiatry]. PMID- 6917422 TI - [Michel--or from nomadism to the creation of spatial exchange. From the cultural association of sector II]. PMID- 6917425 TI - [A nurse speaks of schizophrenia]. PMID- 6917423 TI - [Ludovic--or time, psychosis and transfer. From the cultural association of sector II]. PMID- 6917424 TI - [Martine's story: from the asylum to the life group. From the cultural association of sector II]. PMID- 6917426 TI - [Psychotherapy, the mysterious treatment that arouses fear]. PMID- 6917427 TI - [Clinical study of schizophrenia]. PMID- 6917428 TI - [Cerebral aging and mental disorders of senility]. PMID- 6917431 TI - [Alcoholism in homes for the aged]. PMID- 6917429 TI - [Depressions of the third age]. PMID- 6917430 TI - [Do not neglect the mental status of the elderly]. PMID- 6917432 TI - [Home visits in geronto-psychiatry]. PMID- 6917433 TI - [Geronto-psychiatry: introduction]. PMID- 6917434 TI - [A case of dementia. Approach to the reality of mothering]. PMID- 6917435 TI - [Psychomotor instability of children]. PMID- 6917436 TI - [Theoretical basis of child psychotherapy]. PMID- 6917437 TI - [Hospitalization of the elderly. Current regulations, future perspectives]. PMID- 6917438 TI - [Is there a psychotherapeutic assumption of responsibility for the elderly in an institution?]. PMID- 6917439 TI - [Burkitt's disease]. PMID- 6917440 TI - [Specific aspects of cancers in the tropics]. PMID- 6917441 TI - [Phagedenic cancerized ulcers. Treatment and prevention]. PMID- 6917442 TI - [Bladder neoplasms]. PMID- 6917443 TI - [A case of pleural carcinomatosis]. PMID- 6917444 TI - [Surgical aspects of cancer in Senegal]. PMID- 6917446 TI - [The laboratory of pathological anatomy in the diagnosis of cancer in the tropical zone]. PMID- 6917447 TI - [Health nurse for 92.000]. PMID- 6917445 TI - [Cancers in tropical countries]. PMID- 6917448 TI - [Atomic warfare as a medical problem]. PMID- 6917449 TI - [Routines for dental and oral care. A contribution to a more effective and improved nursing care]. PMID- 6917451 TI - [From the 1981 national convention: Norwegian Nurses' Association's current wage policies]. PMID- 6917450 TI - [From national meeting to national meeting]. PMID- 6917452 TI - [A critique of the theory on self care]. PMID- 6917453 TI - [From the 1981 national convention: crisis in the health sector. No, to drastic cutbacks - yes, to cooperation and challenging ventures]. PMID- 6917454 TI - [A child is born in the Odent hospital]. PMID- 6917456 TI - [A time at sunrise]. PMID- 6917455 TI - [When patients do not fit into a pattern. 2d part of article "A critique of the theory on self care"]. PMID- 6917457 TI - [Children think about death]. PMID- 6917458 TI - [From the 1981 national convention: Norwegian Nurses' Association's organizational development]. PMID- 6917459 TI - [From the 1981 national convention: Norwegian Nurses' Association's action program for 1981-83]. PMID- 6917460 TI - [Monoclonal antibodies - a solution to the cancer puzzle?]. PMID- 6917461 TI - [Supervisory nurse of the school bench. Interview by Magne Rasch]. PMID- 6917462 TI - [The seriously ill child and his family]. PMID- 6917463 TI - [Geriatric care-initiative for consideration]. PMID- 6917465 TI - ["Sysvak" and "Sysbarn" - data system for health centers]. PMID- 6917464 TI - [Nurses' knowledge of drugs]. PMID- 6917466 TI - [Administration of oxygen - when, why, how?]. PMID- 6917467 TI - [Cancer treatment of children in the USA]. PMID- 6917468 TI - [Criterion for desire to save: stormy year for Telemark district. Interview by Ola Gjertsen]. PMID- 6917470 TI - [Library services for nurses]. PMID- 6917471 TI - [MenOpp - menigococcus follow-up studies. A research project requiring team work with nurses]. PMID- 6917469 TI - [How can we provide better conditions to promote breast feeding?]. PMID- 6917472 TI - [Memorable year for DNR (The Norwegian Radium Hospital): special education in oncological nursing]. PMID- 6917473 TI - [We nurses must market our services ourselves]. PMID- 6917475 TI - [Nursing positions in the danger zone]. PMID- 6917474 TI - [Search light on personnel expenditures]. PMID- 6917477 TI - ["The best possible health for all": WHO projects and nursing research in Europe]. PMID- 6917476 TI - [NSF's (Norwegian Nurses' Association) new vice-chairperson. Interview by John Eivind Jensen]. PMID- 6917478 TI - [Primary health services in the polar regions]. PMID- 6917479 TI - [Health and politics in a local community in Sri Lanka]. PMID- 6917480 TI - [Schools and the campaign against narcotics]. PMID- 6917481 TI - [Money saved can result in poor professional nursing care]. PMID- 6917482 TI - [Do you have professional/ethical problems?]. PMID- 6917483 TI - [Course in developing countries' health services]. PMID- 6917485 TI - ["Technical nursing care"]. PMID- 6917484 TI - [Attitude towards the aged]. PMID- 6917486 TI - [Why this lack of professional self-confidence?]. PMID- 6917487 TI - [Hepatitis B]. PMID- 6917488 TI - [Professionalism and socioeconomic welfare]. PMID- 6917489 TI - [It is unreasonable that we should have to fill up our own cars]. PMID- 6917490 TI - [Home care nurses and health visitors have "won" over Soro community: main thing is that we have received service care]. PMID- 6917491 TI - [Drug information: antimalaria agents. I]. PMID- 6917493 TI - [Reorganization of school health services: schoolchildren need an occupational health service]. PMID- 6917492 TI - [Nursing research: steps on the road toward education of clinical specialists in oncological nursing]. PMID- 6917494 TI - [Associations to the fairy tale about the ugly duckling]. PMID- 6917495 TI - [For once this is favored by the daily press]. PMID- 6917497 TI - [Hospital and suicide patients. Do we have a clear position about death by suicide?]. PMID- 6917496 TI - [Nursing care in connection with attempted suicide set in a psychiatric context we can start with empathy and active listening]. PMID- 6917498 TI - [Psychiatrist about people threatening suicide: I am convinced that the least of their needs is to take their own life. Interview by Peter Hjorth]. PMID- 6917500 TI - [Statement by the Danish Nursing Council on the report about school health services: in agreement on the proposal for school health services' future structure]. PMID- 6917499 TI - [Executive Board meeting 13-14 October 1981: new agreements about around-the clock home nursing and still more education]. PMID- 6917501 TI - [Do we treat suicides worse than other patients? People have always committed suicide]. PMID- 6917502 TI - [Suicide and attempted suicide. Suicide has always been most frequent among the divorced and the lonely]. PMID- 6917503 TI - [Personnel's attitude to the suicidal patients: patients are much more emotional in the time after an attempted suicide]. PMID- 6917504 TI - [Danish Nursing Council on introductory discussion from Sector council for continuing education: no more short continuing education courses in the health sector]. PMID- 6917505 TI - [Drug information: antimalaria agents. II]. PMID- 6917506 TI - [Medical Director's management responsibility and function over other personnel groups: no benefit in meddling in each other's management responsibilities]. PMID- 6917507 TI - [Initiative which will lessen pollution hazards of anesthetic gases]. PMID- 6917509 TI - [Glimpse of nursing care from travels around the world: experiences from grassroots outside of the mission]. PMID- 6917508 TI - [Interview with Sister Benedicte, former general prioress and principal of the St. Joseph Hospital nursing school: call me Sister!]. PMID- 6917510 TI - [Information for every single patient]. PMID- 6917511 TI - [Nurses' appointments to the Labor Inspection: we have a ballast in addition to other professional groups]. PMID- 6917512 TI - [Health service for the aged based on professionally qualified assistance]. PMID- 6917513 TI - [Geriatric/long-term medical health and nursing care in the reorganized basic education: increasing need for qualified health and nursing care for the aged]. PMID- 6917514 TI - [Nurses have direct access to the research library]. PMID- 6917515 TI - [Report from China. 1. "we went through the river but kept contact with the river bottom"]. PMID- 6917516 TI - [Instructions for treatment with epidural morphine. Model instructions from the Health Administration for all anesthesiology departments]. PMID- 6917518 TI - [Need for clinical resource persons in nursing]. PMID- 6917517 TI - [Nursing education for the year 2000. 1. The principles for basic education should not be changed]. PMID- 6917519 TI - [Nurses' drug information. Pregnancy and drugs. II]. PMID- 6917520 TI - [Will we have more Fultons or more prevention?]. PMID- 6917523 TI - [Will elucidate the use of EDP in connection with nursing]. PMID- 6917521 TI - [Nursing education for the year 2000. 2. Planning which also includes education]. PMID- 6917522 TI - [The Chinese health care system is on the way up. Report from China. 2]. PMID- 6917524 TI - [On nursing homes and their residents and on the aged who live "at home as long as possible": the one good intention kills the other]. PMID- 6917525 TI - [Happy with a mature County Board chairperson]. PMID- 6917526 TI - [Agreement with budget proposal for 1983 and 1984. Executive Board meeting 8-9 December 1981]. PMID- 6917527 TI - [Great need to study how hospitals are managed. Interview by Inge Rosenkvist]. PMID- 6917529 TI - [Tax orientation for income tax returns]. PMID- 6917528 TI - [Nursing education for the year 2000. 3. Basic education will be preserved also into the year 2000]. PMID- 6917530 TI - [Nurses' drug information. Pregnancy and drugs. II. (contd)]. PMID- 6917531 TI - [Nursing research. Daily needs and hospitalization]. PMID- 6917532 TI - [Employment in sharp contrast to other occupations]. PMID- 6917533 TI - [Optimal care and psychological support for stoma patients]. PMID- 6917534 TI - [Criticism of inaction and a lack of negotiate. Executive Board meeting 12-13 January 1982]. PMID- 6917535 TI - [What does it cost to educate a nurse?]. PMID- 6917536 TI - [Part-time work means that women have to be supported]. PMID- 6917537 TI - [An equal dignified cooperation with the patient]. PMID- 6917538 TI - [A chance to live up to intentions]. PMID- 6917539 TI - [Use and misuse of alcohol]. PMID- 6917540 TI - [The District Administration has not understood the problems]. PMID- 6917541 TI - [It is a farce to call this a Parliament for the Aged. Conference of retirees in Kollekolle 30-31 October 1981]. PMID- 6917542 TI - [Uncomfortable break with ideas in Danish health policy. Interview by Ulla Dietl]. PMID- 6917543 TI - [We don't need a new profession but more self-understanding]. PMID- 6917545 TI - [Educational capacity will increase with legislation]. PMID- 6917544 TI - [Nursing research should be included in basic education. 4th European nursing research conference in Oslo]. PMID- 6917546 TI - [Are patients thirsty in their last hours?]. PMID- 6917547 TI - [What is involved with AB-election?]. PMID- 6917548 TI - [Interpretation of on-call service and work time]. PMID- 6917549 TI - [Work supervision to rearrange its visiting activities]. PMID- 6917550 TI - [Is it on purpose that patients do not get diagnosis?]. PMID- 6917551 TI - [It is important that leadership education and profession are connected. Interview by Ulla Dietl]. PMID- 6917552 TI - [Further education of continued education teachers stopped by refusal]. PMID- 6917553 TI - [Maturity must constantly be evaluated]. PMID- 6917554 TI - [Students ought not to stand alone]. PMID- 6917555 TI - [Sports and music are a real part in treatment]. PMID- 6917557 TI - [Inside environment and illness symptoms in schools]. PMID- 6917556 TI - [We have personal experiences to draw upon]. PMID- 6917558 TI - [Patients' sexual needs are often neglected]. PMID- 6917559 TI - [Educational initiatives follow closely. Executive Board meeting 9-10 February 1982]. PMID- 6917560 TI - Biennial report of the president. PMID- 6917561 TI - Come fly with me: keynote address. PMID- 6917562 TI - The accelerating effect of bovine plasma HMW kininogen on the surface-mediated activation of factor XII: generation of a derivative form (active kininogen) with maximal cofactor activity by limited proteolysis. PMID- 6917564 TI - Simple chromogenic peptide substrate assays for determining prekallikrein, kallikrein inhibition and kallikrein "like" activity in human plasma. PMID- 6917563 TI - Immunoelectrophoretic studies of prekallikrein in human plasma. AB - Using a rabbit anti-human prekallikrein antibody crossed immunoelectrophoresis (CIE) and Laurell rocket antigen determinations were done in plasma of subjects with Fletcher (prekallikrein, PKA), Fitzgerald (high molecular weight kininogen), Hageman (XII), and PTA (XI) deficiencies as well as in patients with activation of coagulation (intravascular coagulation syndromes). Abnormal CIE patterns were seen in the Fletcher and Fitzgerald deficient plasmas and also in some of the patients with intravascular coagulation. In vitro studies of plasma treated with thrombin, plasmin, and contact activating agents indicated that abnormal CIE patterns and increased PKA antigen levels were indicative of activation of the Hageman factor dependent pathway and not the result of plasma clotting by thrombin. In vivo activation of the Hageman factor dependent pathway frequently results in an abnormal CIE and a low PKA antigen level. PMID- 6917565 TI - [Impressions from a study tour to Bergen]. PMID- 6917566 TI - [Problems related to the giving of medical information]. PMID- 6917568 TI - [Comprehensive care theory: an analysis of Lydia Hall's model]. PMID- 6917567 TI - [Improved patient information - obstacles and problems]. PMID- 6917569 TI - [Role of health care research in health care activities]. PMID- 6917570 TI - [Still one way to link research]. PMID- 6917571 TI - [Growing condition. Interview by Mats Wahl]. PMID- 6917572 TI - [Paulo Freire's theory in Swedish health and nursing care]. PMID- 6917576 TI - [Methods and systems of nursing care. I]. PMID- 6917574 TI - [What exactly is pedophelia?]. PMID- 6917573 TI - Haplotype study. linkage between HLA--A, B, C and Bf alleles: results obtained by different statistical methods. AB - 325 HLA-A, B and Bf haplotypes obtained from family studies were investigated. In addition, 216 of these were tested for HLA-Cw2, Cw4, Cw5. Four different statistical methods were employed to study 2, 3 or 4 loci gametic associations in order to compare the results obtained by these different methods. Our results were then compared with those of other authors who employed similar methods. Piazza's method, used to identify gametic associations, was not able to show any 3 loci associations in our material. The Delta Standard Method employed in conjunction with Factorial Correspondence Analysis was found suitable for the study of chromosomal prevalence in a population. PMID- 6917575 TI - [Geriatric rehabilitation in a general hospital]. PMID- 6917577 TI - [A consistent approach to a patient with a severe behavior disorder]. PMID- 6917578 TI - [Ethical aspects in scientific research - pin-pointed on nursing actions]. PMID- 6917580 TI - [Methods and systems of nursing care. II]. PMID- 6917579 TI - [The hospital is for patients--or isn't it?]. PMID- 6917582 TI - [Psychiatric rehabilitation in the Bierbeek University Psychiatric Center (Belgium)]. PMID- 6917583 TI - [Patient education, a current subject - also for nurses]. PMID- 6917584 TI - [The psychiatric nurse: therapist or conferee?]. PMID- 6917585 TI - [The Glasgow coma scale]. PMID- 6917581 TI - [Professional nursing practice at the H.B.O.-level (Higher Professional Education) - expectations versus reality (I)]. PMID- 6917586 TI - [Professional nursing practice at the H.B.O.-level (Higher Professional Education) - expectations versus reality (II)]. PMID- 6917588 TI - Building political muscle. PMID- 6917587 TI - [Hypocalcemia]. PMID- 6917589 TI - Neurosurgical head nurse. PMID- 6917591 TI - Lifeline. PMID- 6917590 TI - How to implement a quality assurance program. PMID- 6917593 TI - Authenticity: fabric of ethical nursing practice. PMID- 6917592 TI - Tuboplasty: changes for the better. PMID- 6917594 TI - Solving ethical dilemmas in nursing practice. PMID- 6917595 TI - Are nurses' mind sets compatible with ethical practice? PMID- 6917596 TI - The role of discussion in ethics training. PMID- 6917597 TI - The what and how of ethics education. PMID- 6917598 TI - An educational strategy for enhancement of moral-ethical decision making. PMID- 6917599 TI - Ethical juxtapositions in nursing research. PMID- 6917601 TI - Ethical issues in nursing research: access to human subjects. PMID- 6917600 TI - Autonomy, accountability and nursing practice. PMID- 6917602 TI - [Development and research. Ethical guidelines for health care research in Scandinavia]. PMID- 6917603 TI - [Nursing education and confluent teaching. Therapeutic attitudes as a result of integration between thoughts and feelings]. PMID- 6917604 TI - [Nursing care which promotes patient's activity and development. Results of a preliminary study]. PMID- 6917606 TI - [4 nurses - 4 doctorates]. PMID- 6917605 TI - [Research in nursing: perspective - presentation of problem - methods. Contribution from a seminar in research development in nursing, Tromso University, May 1981]. PMID- 6917607 TI - [European health care research on the march]. PMID- 6917608 TI - [Scandinavian nurses and the ICN Congress]. PMID- 6917609 TI - A brain abscess in a ewe (a case report). PMID- 6917610 TI - Conservative therapy for right frontal sinusitis in a Brahman bull. PMID- 6917611 TI - Mucosal impression smears for diagnosis of piglet coccidiosis. PMID- 6917612 TI - Barriers to communication. PMID- 6917613 TI - Fringe benefits: which ones are right for you? PMID- 6917615 TI - Laboratory evaluation of the gastrointestinal tract. PMID- 6917614 TI - Tax-wise: how to take the sting out of taxes. PMID- 6917616 TI - Somatosensory development in puppies. PMID- 6917617 TI - Let the user beware! PMID- 6917619 TI - Veterinary cryotherapy-1. A comprehensive look at uses, principles, and successes. PMID- 6917618 TI - Spontaneous healing of an open, comminuted metatarsal fracture in a white-tailed deer. PMID- 6917620 TI - Nonsurgical removal of a fishhook from a dog's esophagus. PMID- 6917621 TI - The effects of pregnancy and other factors on the canine ocular fundus. PMID- 6917622 TI - Poisonous snakebites in dogs and cats. PMID- 6917623 TI - Corticosteroid treatment of pannus in a German shepherd. PMID- 6917624 TI - Normal hemogram and blood chemistry values for California desert tortoises. PMID- 6917625 TI - Vitamin A deficiency in pigeons. PMID- 6917626 TI - Malicious mutilation of a horse with sulfuric acid. PMID- 6917627 TI - Ruptured urachus in a foal. PMID- 6917628 TI - Venographic diagnosis of thrombosis of the deep metatarsal vein. PMID- 6917629 TI - Changes in mortality among the elderly: United States, 1940-78. PMID- 6917630 TI - [Changes of kallikrein-kinin system during surgery in patients with pulmonary tuberculosis]. PMID- 6917632 TI - Ethical issues in nursing research. PMID- 6917631 TI - Understanding the family dynamics of incest builds the staff nurse's therapeutic "caring" skills. PMID- 6917633 TI - Using research in practice: mechanisms of drug tolerance. PMID- 6917634 TI - Researchmanship: structures for research productivity. PMID- 6917636 TI - "Discontent and crisis at schools of nursing: the consequences of unmet human needs.". PMID- 6917635 TI - Strategies for teaching nursing research: experiential learning in data analysis. PMID- 6917637 TI - The ethnoscience research technique. PMID- 6917639 TI - Resources for collaborative research. PMID- 6917638 TI - The use of cardiopulmonary assessment skills in the clinical setting. PMID- 6917641 TI - The search for assumptions. PMID- 6917640 TI - Affiliating in stepfather families: teachable strategies leading to stepfather child friendship. PMID- 6917642 TI - "Nurses, I believe, are the persons best equipped to evaluate their own procedures.". PMID- 6917643 TI - Professional thrust - the concept of nursing today. PMID- 6917644 TI - [tRNA- and aminoacyl-tRNA in the rabbit liver in ontogenesis (author's transl)]. AB - The acceptor capacity of tRNAs and tRNA-synthetases activities of liver extracts was compared for rabbits of different age groups. The level of maximum tRNA aminoacylation in vitro of newborn rabbit (3-5 days) liver for glycine, glutamic acid, leucine, tryptophan, and phenylalanine and tRNA of old rabbits (5 years) liver for glutamic acid, leucine, phenylalanine, and glycine was 1,5-3 times lesser in comparison to that of 1 and 2 years rabbits. The pool of endogenous aminoacyl-tRNAs in 3-5 days rabbits liver was also considerably lower for above mentioned amino acids. The results of short-term heating of tRNA preparations in the presence of Mg2- given the possibility to assume that the decreases tRNA preparations in the presence of Mg2+ give the possibility to assume that the decreases tRNA acceptor activity of the newborn animals depends upon the presence of tRNA inactive conformers. Another reason is the greater loss of the CCA-end in mentioned tRNA. None of these factors in the reason of low acceptor activity of old rabbit liver tRNA which seems to be caused by more considerable disturbances in he molecular structure. Aminoacyl-tRNA-synthetases activities of liver extracts of the same age groups increases during development of animals and decrease subsequently in the liver of old (5 years) rabbits. However, dynamics and quantitative characteristics of these changes are not similar for enzymes of different amino acid specificities. PMID- 6917647 TI - [Midwives in USA started own childbirth center with homelike atmosphere]. PMID- 6917646 TI - Mevinolin: a highly specific inhibitor of microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase of radish plants. AB - The fungal metabolite mevinolin, known to be a potent hypocholesterolemic agent, exerts in vitro a strong inhibitory effect on microsomal HMG-CoA reductase from etiolated radish seedlings at a concentration of about three magnitudes lower than the Km towards the natural substrate (S)-HMG-CoA (I50 = 2.5 x 10(-9)M). Beside this, mevinolin significantly inhibits the root elongation of radish as well as of wheat seedlings already at low concentrations of 10 to 100 ppb (= 2.5 x 10(-8) to 2.5 x 10(-7)M). PMID- 6917645 TI - [Behavior of various parameters of the kallikrein-kinin-system in experimental shock and different types of shock sensitivity]. PMID- 6917648 TI - [Nurse midwives here to stay despite physicians' opposition]. PMID- 6917649 TI - [Proposal for a joint Scandinavian labor market]. PMID- 6917650 TI - [Reduction in force catastrophic for care and personnel]. PMID- 6917651 TI - [Personal work - theme for SSN (Scandinavian Nurses' Cooperative)]. PMID- 6917653 TI - [Ingegerd Danell, handicapped nurse: important to do the accustomed work. Interview by Kristina Lindgren]. PMID- 6917652 TI - [Gunilla Pehrsson, employed part-time as nurse anesthetist: family suffers if we both have full time jobs. Interview by Inger Lernevall]. PMID- 6917654 TI - [In a hospital in the USA union crushed by a consultant firm]. PMID- 6917655 TI - [Change for the better for Academic Center after renewed attention]. PMID- 6917656 TI - [International professional work - something for the SHSTF?]. PMID- 6917657 TI - [Ignorance cause of many accidents in nursing care. Interview by Viveka Holmertz]. PMID- 6917658 TI - [Regional health university's proposal for 1985. Joint first term for physicians and nurses]. PMID- 6917659 TI - [Disagreement within the SHSTF about authorization]. PMID- 6917660 TI - [In spite of thousands of STA-MCA bypass operations worldwide since 1967 it is not a routine operation for all neurosurgical hospitals]. PMID- 6917664 TI - [Patients can complain about health care with the Confidential Committee. Interview by Inger Lernevall]. PMID- 6917663 TI - [Collections of all write-ins: we want to keep continued education!]. PMID- 6917662 TI - [Karolinska Hospital: employee conditions getting better]. PMID- 6917661 TI - [Rut has a job as hygiene nurse for 7 years. "Interest in hygiene remains very strong". Interview by Jan Thomasson]. PMID- 6917665 TI - [Definite laws and regulation about copying of articles. First ask permission!]. PMID- 6917666 TI - [New study circle in health care functions: many have asked for this]. PMID- 6917669 TI - [District nurse in Matteus-project: we have better contact with our patients]. PMID- 6917667 TI - [Government plans against the right to strike. Interview by Jan Thomasson]. PMID- 6917668 TI - [Health care research - patient-oriented. Interview by Monika Trozell]. PMID- 6917670 TI - [Entire day of telephone time with Mona in Kungshamn. Interview by Viveka Holmertz]. PMID- 6917671 TI - [Decision for a change of name - but for what purpose?]. PMID- 6917672 TI - [Joint decision making: local government in West Norrland makes an agreement but KTK (Municipal Employee Cartel) waits]. PMID- 6917673 TI - [When students take over a ward]. PMID- 6917674 TI - [SHSTF-members on a study trip to Solidarity in Poland]. PMID- 6917675 TI - [Marianne, basic education: everyone should have continued education in medicine and surgery. Interview by Inger Lernevall]. PMID- 6917676 TI - [Medical society VD after decision to leave the Saco/SR. We cannot think of ourselves as being placed under the KTK]. PMID- 6917677 TI - [District nurse could not foresee sudden deterioration]. PMID- 6917679 TI - Hospital reputation. PMID- 6917678 TI - [Incorrect analysis results cause of an unnecessary operation]. PMID- 6917680 TI - Law and the lamp: consent and the mentally incompetent adult. PMID- 6917681 TI - Job satisfaction among Alberta nurse educators. Part 1. PMID- 6917682 TI - Reduced urine kallikrein excretion and antikaliuresis by chlorazanil in rats. AB - In normal conscious female Sprague-Dawley rats chlorazanil (3 mg/kg intraperitoneally) reduced urine kallikrein excretion by approximately 80%. Thus, urine kininogenase activity decreased from 54 +/- 5 U/kg/3 hrs to 10 +/- 2 U/kg/3 hrs and urine TAMe-esterase activity decreased from 34 +/- 1.5 mEU/kg/3 hrs to 7.4 +/- 1.0 mEU/kg/3 hrs. In addition kidney kallikrein content decreased by approximately 50% from 0.76 +/- 0.03 U/kidney to 0.40 +/- 0.07 U/kidney at three hours post treatment. Chlorazanil (3 mg/kg intraperitoneally) increased urine sodium excretion from 0.48 +/- 0.04 mmol/kg/3 hrs to 2.48 +/- 0.98 mmol/kg/3 hrs and decreased the potassium excretion from 1.06 +/- 0.45 mmol/kg/3 hrs to 0.29 +/ 0.09 mmol/kg/3 hrs. Comparable antikaliuretic doses of amiloride (5 mg/kg intraperitoneally) or triamterene (10 mg/kg orally) did not change urine kallikrein excretion It is suggested that chlorazanil inhibits kidney kallikrein synthesis perhaps by an innate antimineralocorticoid-like effect. PMID- 6917683 TI - From novice to expert. PMID- 6917684 TI - Strategies for direct third-party reimbursement for nurses. PMID- 6917685 TI - Nursing care in childhood cancer. CE. PMID- 6917686 TI - Nursing care in childhood cancer: retinoblastoma. PMID- 6917687 TI - Nursing care in childhood cancer: methadone. PMID- 6917688 TI - Nursing care in childhood cancer: adolescence. PMID- 6917689 TI - Nursing care in childhood cancer: coping. PMID- 6917691 TI - Am I active in nursing? PMID- 6917690 TI - Nursing care in childhood cancer: late effects of therapy. PMID- 6917692 TI - Nurses today - a statistical portrait. PMID- 6917694 TI - Nursing diagnosis: refining the system. PMID- 6917693 TI - Synthetic blood: a future alternative. PMID- 6917697 TI - Help for the helper. PMID- 6917696 TI - Complexities of managing diabetes. PMID- 6917695 TI - What's best for Willie? PMID- 6917698 TI - Help for the helper. Confronting a chemically-impaired colleague. PMID- 6917700 TI - Help for the helper. What the SNAs are doing in Maryland. PMID- 6917699 TI - Help for the helper. First-hand views of recovery. PMID- 6917701 TI - Help for the helper. What the SNAs are doing in Georgia. PMID- 6917702 TI - Help for the helper. What the SNAs are doing in Ohio. PMID- 6917704 TI - Help for the helper. An employee assistance program. PMID- 6917703 TI - Help for the helper. What the SNAs are doing in Tennessee. PMID- 6917705 TI - The pupil check. PMID- 6917706 TI - Hospital vacancies. PMID- 6917707 TI - Diagnosing the problems in stroke. PMID- 6917708 TI - Continuous drip morphine. PMID- 6917709 TI - The image of the nurse in motion pictures. PMID- 6917710 TI - Dealing with feelings. Affirmations. PMID- 6917711 TI - Rural nursing. PMID- 6917712 TI - Reducing the anxiety and pain of childbirth through hypnosis. PMID- 6917714 TI - The right and responsibility to diagnose. PMID- 6917713 TI - What the new test will test. PMID- 6917715 TI - Immunoreactive glandular kallikrein in rat plasma: a radioimmunoassay for its determination. AB - A radioimmunoassay (RIA) has been developed to measure immunoreactive glandular kallikrein in rat plasma. To prevent the binding of radioactive kallikrein to plasma inhibitors, 125I-kallikrein was inactivated with phenylmethylsulfonyl fluoride (PMSF), a procedure that maintained 125I-kallikrein immunoreactivity. Different volumes of plasma displaced 125I-PMSF-kallikrein in a parallel fashion to the kallikrein standard curve. The sensitivity of the RIA was 200 pg, and the recovery of nonradioactive active kallikrein added to plasma was 58.7%. The concentration of immunoreactive glandular kallikrein in normal rat plasma averaged 47.1 +/- 1.7 (SE) ng/ml. Bilateral nephrectomy caused a threefold increase in circulating glandular kallikrein (50 +/- 2.7 to 167 +/- 7 ng/ml; P less than 0.001). REmoval of the submandibular and sublingual glands significantly decreased its concentration from 52 +/- 2.3 to 34 +/- 1.6 ng/ml (P less than 0.001). Immunoreactive glandular kallikrein was higher in the submandibular gland vein than in arterial blood (venous: 94 +/- 10.5; arterial: 64 +/- 6.3 ng/ml; P less than 0.05) and was lower in the renal venous blood (venous: 44 +/- 2.2; arterial: 53 +/- 2.6 ng/ml; P less than 0.05). In conclusion, this study shows that the use of 125I-PMSF-kallikrein as tracer prevents the interference in the RIA caused by plasma protease inhibitors. It also indicates that the submandibular gland is an important source of the immunoreactive glandular kallikrein in rat plasma and that the kidney probably participates in its metabolism. Glandular kallikrein released by the submandibular gland into the circulation may participate in regulating local blood flow before it is inactivated by plasma inhibitors. PMID- 6917716 TI - Determination of 35S-aminoacyl-transfer ribonucleic acid specific radioactivity in small tissue samples. PMID- 6917717 TI - [Effect of hyperbaric oxygenation on microcirculation and various indicators of the kallikrein-kinin system in pregnant diabetics]. PMID- 6917718 TI - Nitrogen dioxide exposure and alveolar macrophage elastase in hamsters. AB - Adult male hamsters were exposed to 30 +/- 5 ppm nitrogen dioxide (NO2) for periods as long as 30 days. Alveolar macrophages obtained by lung lavage at 0, 2, 5, 14, and 30 days of exposure were present in increased amounts, with the greatest increase 8 times the control amount at 14 days of NO2 exposure. No elastolytic activity was observed in the cell-free lavage fluid. Alveolar macrophages were cultured in serum-free medium for 1 to 6 days. The mediums were collected and assayed for elastolytic activity using Sepharose-coupled [3H] soluble elastin as substrate. Elastolytic activity in the secretions increased significantly at days 2 and 5 but was greatest after 14 days of NO2 exposure. These observations indicate that the secretions of alveolar macrophages from hamsters exposed to NO2 increased elastolytic activity. This activity correlates with the duration of NO2 exposure for periods as long as 14 days. The increased elastolysis observed appears to be dependent on increased numbers of macrophages rather than on increased elastolytic secretion per cell. Inhibition studies with a battery of elastase inhibitors indicated that the elastase(s) secreted from NO2 and control alveolar macrophages have identical properties. The response of hamster macrophage elastase to inhibitors differs from that observed in the mouse and in humans in that it is not inhibited by EDTA, human serum or 1,10 phenanthroline. PMID- 6917719 TI - Response of the aging hamster lung to elastase injury. AB - The effect of age on the induction of emphysema in hamsters was investigated by administering porcine pancreatic elastase endotracheally to old (18 months of age) and young (4 months of age) hamsters; age-matched untreated animals served as controls. Lung volumes, quasi-static deflation volume pressure relations, and mean linear intercept, an index of alveolar size, were measured. Elastase-treated young hamsters demonstrated an increased volume of air in the lungs at a transpulmonary pressure of 25 cm H2O and an increased mean linear intercept. The lungs of old elastase-treated animals showed less pronounced changes than those of young hamsters in lung volume at transpulmonary pressure of 25 cm H2O and in mean linear intercept. Untreated old hamsters had a larger lung volume at a transpulmonary pressure of 25 cm H2O and an 85% increase in total lung collagen. Age-related alterations in connective tissues may account for the increased resistance of old lungs to injury by pancreatic elastase. PMID- 6917720 TI - Nurses, defense officials meet about shortage, military preparedness. PMID- 6917721 TI - Can an OR nurse tell the surgeon to stop? PMID- 6917722 TI - Consider your needs before selecting an OR consultant. PMID- 6917723 TI - The Broviac catheter: OR technique. PMID- 6917724 TI - Caring for children needing anesthesia. PMID- 6917726 TI - Association of operating room nursing. Pre-Congress issue. PMID- 6917725 TI - Ambulatory surgery growing at rapid pace. PMID- 6917727 TI - AORN consultants offer assistance on education questions. PMID- 6917728 TI - Intrauterine treatment of fetal hydronephrosis. PMID- 6917729 TI - Fetal therapy: issues we face. PMID- 6917730 TI - Clinical ladders and specialty teams. PMID- 6917731 TI - A teaching plan for surgical scrubbing, gowning, and gloving. PMID- 6917732 TI - Home care keeps children out of the hospital. PMID- 6917733 TI - Don't neglect routine staff meetings. AB - Staff meetings are essential to good staff communication. Meetings help keep the grapevine from growing so big that it strangles the group with its rumors. By holding regular meetings with your staff, you create a consistency in your communications that helps prevent problems that you don't even suspect from cropping up. All personnel should attend the meetings. This way everyone hears news at the same time. Be consistent in your use of meetings. Meetings are more effective if you have a planned agenda and a firm time schedule. Encourage your staff to use meetings to talk out problems that affect the group. Once the meeting is over, encourage them to leave their feelings in the room. Many leaders are reluctant, for a variety of reasons, to hold meetings with their staffs. But it's like dieting and exercise; the more you do it, the easier it becomes. This type of meeting will pay rich dividends in staff personal and professional growth and in improved communication. The sense of participation that can be gained by the effective use of staff meetings can lead to high morale and effective staff performance. As you begin to see the results of a cohesive staff functioning together well, you will realize the routine staff meeting is a management tool that should not be overlooked or underused. PMID- 6917734 TI - Building support for the circulator issue. PMID- 6917735 TI - A regional course in OR nursing. PMID- 6917736 TI - Recommended practices for documentation of perioperative nursing care. From the AORN Recommended Practices Subcommittee. PMID- 6917737 TI - Recommended practices for traffic patterns in the surgical suite. From the AORN recommended Practice Subcommittee. PMID- 6917738 TI - Hospitals feel pinch as costs go up and federal funds go down. PMID- 6917739 TI - Nursing interventions to improve adjustment to aging. PMID- 6917740 TI - Rehabilitation nursing education in a specialty hospital. PMID- 6917741 TI - Bioethics of cancer nursing. PMID- 6917743 TI - Nurses, spirituality, and clients. Part I. The spiritual aspect of nursing care. PMID- 6917742 TI - Tolerant Staphylococcus aureus causing vertebral osteomyelitis. AB - Vertebral osteomyelitis due to Staphylococcus aureus was suppressed by not cured by optimal therapy with nafcillin sodium; cure eventually was achieved by treatment with cefazolin sodium and gentamicin sulfate. This is vivo result correlated with in vitro observations that showed that the infecting organism was inhibited but not killed by prolonged incubation with nafcillin or cefazolin; killing was readily achieved in vitro by adding subinhibitory concentrations of gentamicin. Bacterial tolerance in this case appeared to be responsible for the failure of vertebral osteomyelitis to be cured by accepted therapy with beta lactam antibiotics. PMID- 6917744 TI - Nurses, spirituality, and clients. Part 2. The art of winning the money game and having your whole life work. PMID- 6917745 TI - Sharing love with the clients and staff in an alcohol rehabilitation center. PMID- 6917746 TI - Nurses teach assertive self-health care in communities and universities: philosophy of self-health care. PMID- 6917747 TI - The nurse and the law: intensive care. PMID- 6917748 TI - Parents' view of newborn intensive care. PMID- 6917749 TI - The role and influence of nurses at hospital administrative level. PMID- 6917750 TI - Don't despair -- dying can be painless. PMID- 6917751 TI - Perspectives of leadership and the needs of nursing. PMID- 6917752 TI - Requirements for nursing staff in acute psychiatric wards -- a Victorian study. PMID- 6917753 TI - A non-scientistic view of communication in nursing and the allied health sciences. PMID- 6917754 TI - Loss and grief. PMID- 6917756 TI - Modern concepts and trends in nursing administration in hospitals. PMID- 6917755 TI - Homebirths--is this a suitable matter of legislation? PMID- 6917757 TI - How to recognise and help agoraphobics. PMID- 6917758 TI - Rubella immunisation, a tangle of absurdities and some comments. PMID- 6917759 TI - Hospice care at Kalyra. PMID- 6917761 TI - WBPTT and ACT clotting time methods for use in hemodialysis. PMID- 6917763 TI - Wegener's granulomatosis treated by plasmapheresis and hemodialysis. PMID- 6917762 TI - The role of the nurse practitioner in the care of hemodialysis patients. PMID- 6917760 TI - Quality assurance vs cost containment: "damned if you do, damned if you don't". PMID- 6917764 TI - Independence for the visually impaired continuous ambulatory peritoneal dialysis (CAPD) patient. PMID- 6917765 TI - The need for stimulation and the choice of nursing as a career. PMID- 6917766 TI - [Some features of [1-14C] leucine exchange in rat liver during acute oxythiamine avitaminosis]. AB - The leucine content in rat liver and blood serum under acute oxythiamine avitaminosis is decreased. Simultaneously oxythiamine inhibits the activity of alpha-ketoisocaproate dehydrogenase resulting in a decrease of leucine catabolism in the liver. The level of total tRNA in hepatocyte cytosol is lowered, the radioactivity of leucine in aminoacyl-tRNA on the 6th min after injection of [1 14C]leucine is increased approximately 1.5-fold as compared to normal. The radioactivity of leucine in blood serum and aminoacyl-tRNA is directly significantly correlated with the content of leucine incorporated into the proteins, while the level of intracellular [14C]leucine is not correlated with the protein radioactivity (r=-0.154,p greater than 0.5) or with blood serum amino acid radioactivity (r=-0.184, p greater than 0.5). The results obtained thus indicate that 1) in acute oxythiamine avitaminosis when the labelled amino acid is incorporated within 3-6 min the label is "concentrated" in blood serum resulting in increased specific radioactivity of the protein in rat liver; 2) in blood serum leucine is predominantly utilized during protein biosynthesis; 3) acute oxythiamine avitaminosis has no significant effect on protein biosynthesis in rat liver; 4) specific radioactivity of the protein cannot serve as an index of protein synthesis rate. PMID- 6917769 TI - Intercollegiate sports participation and non-medical drug use. AB - The purpose of this study was to determine if participation in a competitive intercollegiate sports programme would modify the non-medical drug and substance use behaviour patterns of the participants as compared with their non-athletic counterparts. Sixty-seven intercollegiate swimmers and members of varsity swim teams at six American universities comprised the athlete population and were compared with 678 non-athletic under-graduates. A chi-square analysis of the data indicated no significant difference between athlete and non-athlete with respect to the most commonly used mood-modifying drugs. There was also no significant difference in drug-use behaviour between male and female athletes with respect to non-medical use of the common mod-modifying drugs although there was a significant difference between male and female athletes with respect to anabolic steroid use. A level of significance at the 0.05 level of confidence indicated male athletes more likely to use anabolic steroids than female athletes. PMID- 6917768 TI - [Effect of salivary glands on intensity of kininogenesis in blood]. PMID- 6917767 TI - Effect of acute perinatal asphyxia on development of the lung and brain in the rat. AB - Fetal rats were exposed to asphyxia by compression of the umbilical vessels, and the animals were studied shortly after delivery, close to term (21st fetal day). Following asphyxia on the 20th fetal day, the lungs appeared immature. The surface active phospholipids, disaturated lecithin and phosphatidylglycerol, as well as the elastic tissue around the alveoli were lower than in the control littermates. However, lung maturity was little affected following asphyxia on the 17th-18th fetal day. As studied in the brain, hemorrhages in the periventricular area, sometimes intraventricular hemorrhages, were evident (asphyxia on the 17-18 and 20th fetal days). In addition, cells in cerebral cortex were altered following asphyxia of 17 - to 18-day-old fetuses. The present animal model clarifies the mechanism of increased incidence of respiratory distress syndrome following acute asphyxia and may prove to be useful in studies of pathogenesis of periventricular hemorrhages. PMID- 6917770 TI - Effects of the resin and smoke condensate of Cannabis sativa on the oestrous cycle of the rat. AB - This study is concerned with variations in the oestrous cycle of the Sprague Dawley rat following the intraperitoneal administration of maize oil solutions of Cannabis sativa resin and smoke condensate in doses of 10 and 20 mg/kg. Oestrus was shortened with doses of both the resin and the smoke condensate, whereas dioestrus was lengthened with the 20 mg/kg smoke condensate. ALso observed was a lengthening of postoestrus following the administration of 20 mg/kg of either the resin or the smoke condensate. PMID- 6917771 TI - The ethics of suicide intervention: seen as a nursing problem. PMID- 6917772 TI - No visible scarring. PMID- 6917773 TI - Performance evaluation. PMID- 6917774 TI - Associations of properdin factor B with melanoma. AB - We investigated 98 melanoma patients and 135 normal controls for differences in phenotype and genotype frequencies at the properdin factor B locus. A significant negative association with the Bf-F allele and melanoma was found, resulting in an estimated relative risk of 0.5. The estimated relative risk for developing melanoma among people with the Bf-FF genotype is 0.07. The Bf-S phenotype was significantly increased among the melanoma sample, with an estimated risk of 6.5. The data suggest association of the Bf locus with a melanoma protection and/or susceptibility gene(s). PMID- 6917775 TI - Scalp hypothermia to prevent adriamycin-induced hair loss. PMID- 6917776 TI - Changing nurses' perceptions of cancer and cancer care. PMID- 6917777 TI - Nursing implications of hepatic artery infusion. PMID- 6917778 TI - The fetus and independent life. PMID- 6917779 TI - The fetus and independent life. Introduction. PMID- 6917780 TI - A possible role for catabolin in tissue remodelling and repair. AB - Catabolin is a recently discovered polypeptide of 17 000 molecular weight which stimulates connective and skeletal tissue cells to degrade their extracellular matrix. It is produced by a variety of cell types and is believed to be part of a family of cellular messengers which interact to control tissue remodelling and repair in both physiological and pathological situations. PMID- 6917781 TI - Glucose homeostasis in the perinatal period: the critical role of pancreatic hormones and exogenous substrates in the rat. AB - Birth in most mammalian species is characterized by an abrupt change from a high carbohydrate and low fat diet to a high fat and low carbohydrate diet. As the supply of glucose from the milk is not sufficient to cover the glucose needs of several tissues (such as the brain and the red blood cells) and as liver glycogen stores are exhausted within 12 hours of delivery, the newborn rapidly becomes dependent on its capacity for efficient gluconeogenesis. Among the factors that control the appearance of gluconeogenesis in the liver of the neonate, the pancreatic hormones play a crucial role. Studies in the rat have shown that the rise in plasma glucagon and the fall in plasma insulin which occur immediately after birth are the main determinants of the appearance of liver phosphoenolpyruvate carboxykinase (GTP), the rate-limiting enzyme of glyconeogenesis in this species. However, when this enzyme has reached its adult values in the liver 12 to 24 hours after birth, other factors involved in the regulation of hepatic gluconeogenesis. In order for it to maintain a high rate of gluconeogenesis the liver of the neonate must be supplied with sufficient amounts of gluconeogenic precursors and of non-esterified fatty acids. Studies in the rat have shown that active fatty acid oxidation is necessary to support gluconeogenesis by providing essential cofactors such as acetyl-CoA and NADH. The relevance of these studies for the understanding of neonatal glucose homeostasis in man is discussed. PMID- 6917782 TI - The central control of fetal breathing and movements. AB - In fetal lambs after 115 days gestation breathing movements become episodic in association with electrocortical differentiation into predominantly high voltage slow or low voltage rapid activity, the latter characteristic of rapid eye movement sleep. Section of the brainstem at or above the colliculi dissociates fetal breathing from electrocortical activity. It is included that breathing is inhibited, towards the end of gestation, by a supracollicular mechanism during high voltage activity. After brainstem transection at the colliculi hypoxia no longer causes an arrest of fetal breathing, which often becomes more vigorous. The arrest of breathing in normal fetuses subjected to mild hypoxia is also attributed to a supracollicular mechanism. The pattern of fetal skeletal movements and of the spinal segmental reflexes is related to electrocortical activity near term; both are suppressed by hypoxia. The hypothesis is discussed of a central control centre, excited directly or indirectly by hypoxia, which inhibits fetal movements including breathing. Its possible location is considered. PMID- 6917783 TI - Changing patterns of steroid production in the fetus and placenta and their effects on development. AB - A variety of radioimmunoassays specifically characterized for use with fetal and maternal ovine plasma have been used to measure steroid hormone concentrations in small plasma samples drawn simultaneously from mother and fetus. By repeated sampling from the same animal preparation the changes over time of plasma concentrations of cortisol, pregnenolone and its sulphate, and oestrone and oestrone sulphate have been systematically studied. In animals delivering spontaneously at term the fetal plasma cortisol concentration rises between 120 and 130 days gestation and plays an important part in the maturation of several vital physiological systems, including the fetal thyroid axis. In normal term deliveries and premature deliveries induced by synthetic adrenocorticotropin (ACTH(1-24), 1 microgram h-1), the concentration of oestrone sulphate in maternal plasma increases before the fetal plasma concentration. Fetal and maternal oestrogens are probably important in the control of the low-grade tonic myometrial activity that occurs throughout gestation, in the initiation of labour and in the control of uterine blood flow. Low-grade tonic myometrial activity affects fetal oxygenation, fetal breathing and the fetal sleep state and may constitute a pathway through which the mother influences fetal development, with important physiological and possibly pathological consequences. PMID- 6917784 TI - Radiation risks associated with diagnostic radiology. PMID- 6917785 TI - The nephrotic syndrome. PMID- 6917786 TI - Does cadmium administration change peptide elongation in rat liver? PMID- 6917787 TI - Negative cooperativity in adenylate formation catalysed by beef pancreas tryptophanyl-tRNA synthetase: influence of tRNATrp. PMID- 6917791 TI - [Nutrition in cardiovascular diseases]. PMID- 6917788 TI - [Staphylococcal infection and the problems of their prevention]. PMID- 6917792 TI - [Acute pancreatitis]. PMID- 6917789 TI - [Calendar of prophylactic inoculations]. PMID- 6917790 TI - [Ankylosing spondylarthritis (Bechterew's disease)]. PMID- 6917793 TI - [Pregnancy and labor in multiple pregnancy]. PMID- 6917794 TI - [Health education in the dispensary care of the population]. PMID- 6917795 TI - [Deontology in obstetrics]. PMID- 6917796 TI - [Characteristics of the care of mental patients]. PMID- 6917798 TI - [Emergency states in cardiology]. PMID- 6917797 TI - [Importance of acupuncture in modern medicine]. PMID- 6917799 TI - [Epidemiological cancer studies in the USA]. PMID- 6917800 TI - [Harm of passive smoking (material for talks)]. PMID- 6917801 TI - [Modern protection from influenza]. PMID- 6917802 TI - [Mustard compresses]. PMID- 6917804 TI - [The induction of abortion and the priming of the cervix with prostaglandin F2 alpha and prostaglandin E2 by intra-amniotic, extra-amniotic and intra-cervical application (author's transl)]. PMID- 6917803 TI - [IUD under the aspects of sexual medicine (author's transl)]. PMID- 6917805 TI - [The early postoperative as well as the late consequences of cervix conization. A critical examination of 414 conizations (author's transl)]. PMID- 6917807 TI - [Thrombophilic factors in the treatment of vulvar cancer (author's transl)]. PMID- 6917806 TI - [Psammoma bodies in cervical smears (author's transl)]. AB - Two cases with the finding of psammoma bodies in the cervical smear are reported. The first patient was 44 years old and without clinical evidence of disease. A routine Papanicolaou smear showed multiple psammoma bodies either free or surrounded by an epithelium without striking atypia. The cytologic findings were reported as suspicious of ovarian or endometrial adenocarcinoma. Histologically a serous papillary cystadenocarcinoma was found. Three years later there is no sign of recurrence. The second patient was 72 years old and presented pleural and ascitic effusions, with tumour cells of adenocarcinoma. The cervical smear showed psammoma bodies and tumour cells of adenocarcinoma. She died without histological examination. PMID- 6917808 TI - [The problem of lowering the age limit for breast cancer screening in women under the compulsory health insurance system (author's transl)]. PMID- 6917809 TI - [Successful further prolongation of immature twin pregnancy by tocolysis and re cerclage following unavoidable delivery of the first foetus after emergency cerclage (author's transl)]. AB - The article reports on a twin pregnancy with EPH gestosis in a 20-year old primipara which could be prolonged by tocolysis and emergency cerclage after signs of premature delivery and prolapse of the amniotic sac in the 28th/29th pregnancy week. At the beginning of the 30th gestation week there was an unavoidable delivery of the first twin (920 g) who survived for 5 days only due to immaturity and hypotrophy. Directly after delivery of the first twin the pregnancy for the second twin was prolonged by renewed tocolysis and renewed circular suture of the cervix. This enabled the second child, whose growth had been retarded like that of the first one, to continue to grow for some time. Unavoidable delivery of the second twin (1,650 g) eventually occurred at the beginning of the 32nd week of pregnancy. The eutrophic child survived without the slightest complication. This case is presented in detail and discussed, including the histology of the placenta. The most important points for enabling the survival of a twin foetus are sufficient tocolysis, a satisfactory technique for occlusion of the os uteri, as well as exclusion and prevention of chorioamnionitis. PMID- 6917810 TI - [Hypotonia in pregnancy: implied risks, differential diagnosis, consequences (author's transl)]. PMID- 6917811 TI - [A new echographic method for the determination of the ossification centres in the fetal knee (author's transl)]. AB - A method is described, which permits the determination of fetal maturity by ultrasonic measurement of the ossification centres. This method provides the same data as the x-ray examination without any irradiation and even at an earlier stage of pregnancy. The technique to determine the lower femoral and the upper tibial centre is explained and the advantages of this ultrasonic method for determination of fetal maturity are discussed. PMID- 6917813 TI - "Take my hand". PMID- 6917814 TI - Affective nursing touch. PMID- 6917812 TI - [Cytogenetic, gynaecological and sonographic aspects of twin pregnancy with parental Robertsonian translocation 13/14 (author's transl)]. AB - A prenatal chromosome analysis for a parental Robertsonian translocation 13/14 is absolutely imperative. In the present case of a twin pregnancy, it was possible to present the chromosome complement of only one foetus. Since this foetus showed the Robertsonian translocation in the same form as the phenotypically healthy mother, and since the ultrasound findings were normal, it was concluded that foetus I was normal. Further measures for the cytogenetic analysis of foetus II were abandoned after the first amniotic sample could not be analysed. At the time of the amniocentesis this child was retarded when compared to foetus I. Since the life expectancy of a possibly chromosomally unbalanced child is slight, it was not necessary for the parents to take further steps. During the rest of the pregnancy however, this difference in the development of the children evened out unexpectedly and two phenotypically healthy children were born. The implications of a delayed growth rate as an indication of abnormal foetal development are discussed. PMID- 6917816 TI - Come sing along with me. PMID- 6917815 TI - Falls: kinds, causes and prevention. PMID- 6917817 TI - Health fairs for older adults. Steps to the fair... PMID- 6917818 TI - Health fairs for older adults. The big day... PMID- 6917820 TI - Nutrition: fast food... is it junk? PMID- 6917819 TI - Foot problems of elderly diabetics. PMID- 6917821 TI - Drugs and the elderly: for arthritis--plain aspirin or an aspirin alternative? PMID- 6917823 TI - Rural oncology project - a year in review. PMID- 6917822 TI - 70+ and going strong. Dorothy Kelly and Mary Mullane: footloose and fancy free. PMID- 6917824 TI - Updated survey of graduates. PMID- 6917825 TI - Genetic polymorphism of glycine-rich beta-glycoprotein in the Italian population. AB - Genetic polymorphism of glycine-rich beta-glycoprotein (GBG) was studied in populations from northern and southern Italy, respectively. Gene frequencies were as follows: northern Italy (n = 431): GbS = 0.7675, GbF = 0.2049, GbS 0.7 = 0.0127, GbF1 = 0.0139; southern Italy (n = 161): GbS = 0.7050, GbF = 0.2360, GbS 0.7 = 0.0373, GbF1 = 0.0217. Comparison of these two populations with the Swiss population revealed a significant drift in gene frequencies from north to south. A new GBG phenotype, supposedly heterozygous, with a slow migrating F band and a regular S band in agarose electrophoresis was observed. PMID- 6917826 TI - Toward a unique knowledge base in nursing. PMID- 6917827 TI - Boundaries of personal space. PMID- 6917828 TI - Grief in adolescent mothers after an infant death. PMID- 6917830 TI - Nursing practice conceptualized: an interaction model. PMID- 6917831 TI - Role considerations in care of the dying patient. PMID- 6917829 TI - Choice of injection site, locus of control, and the perception of momentary pain. PMID- 6917833 TI - [Pill-mania]. PMID- 6917834 TI - [Dorothy Johnson's model]. PMID- 6917835 TI - [Methods for resolving problems of parents of asthmatic children]. PMID- 6917832 TI - [Administration of cephalosporins]. PMID- 6917837 TI - [The role of the nurse in the service of the new doctor in a family practice unit]. PMID- 6917839 TI - [Nurses and death]. PMID- 6917838 TI - [Legal aspects: the incident report]. PMID- 6917840 TI - Poetry play: a method of communication with pediatric clients. PMID- 6917836 TI - [Point blank. The sick-nurse: a hellish myth!]. PMID- 6917841 TI - Living with childhood cancer: healthy siblings' perspective. PMID- 6917843 TI - Translating health knowledge into health behavior. PMID- 6917842 TI - Health education translated into health behavior. PMID- 6917844 TI - Child-rearing practices: child with chronic illness and well sibling. PMID- 6917845 TI - The antimicrobial susceptibility of anaerobic bacteria in a London teaching hospital. PMID- 6917846 TI - Interaction of added amphiphilic lipids with the membrane of intact human erythrocytes to induce change in the cell shape. AB - Addition of an appropriate amount of amphiphilic lipid, such as fatty acid, lysophospholipid and medium-chain phospholipid, into a suspension of human erythrocytes (pH 7.4) at 37 degree C resulted in their incorporation into the membrane and induction of a cell shape change of crenation (echinocyte spherocyte) type without causing hemolysis. The extent of the shape change was dependent on the amount of the lipid incorporated and the crenation disappeared on removing the incorporated molecules from the membrane. The crenation induced by acidic lipids was further altered drastically by resuspending the treated cells in media of pH 6, 7, and 8, whereas that induced by choline-phospholipid or -lysophospholipid was not so pH-dependent. Based on these results, the mechanism of this shape change is discussed. PMID- 6917847 TI - A continuous, spectroscopic analysis of the kinetics of elastase secretion by neutrophils. The dependence of secretion upon receptor occupancy. AB - We have developed a continuous spectroscopic method to analyze the kinetics of elastase secretion by human neutrophils. We have used the elastase-specific substrate methylsuccinylalanylalanylprolylvalylmethylcoumarin amide (Castillo, M. J., Nakajima, K., Zimmerman, J., and Powers, J. C. (1979) Anal. Biochem. 99, 53 64), which liberates the fluorophore, aminomethylcoumarin, when cleaved by elastase. We find that secretion of elastase in cytochalasin B-treated cells is initiated within approximately 5 s of exposure of the cells to the fluoresceinated chemotactic peptide stimulus, N-formyl norleucylleucylphenylalanylnorleucyltyrosyllysine-fluorescein, and that secretion is completed within 30 s. The kinetics of this response is only slightly dependent on the concentration of the stimulus. Up to 100% (approximately 0.5 pg/neutrophil) of the elastase can be released in a dose-dependent manner by stimulated cells. We have also used this fluoresceinated stimulus and an antibody to fluorescein (Sklar, L. A., Oades, Z. G., Jesaitis, A. J., Painter, R. G., and Cochrane, C. G. (1981) Proc. Natl. Acad. Sci. U. S. A. 78, 7540-7544) to probe the temporal relationship between the binding of stimulus to the receptors and the cellular response. We find that the entire response is elicited by the binding which occurs within the first 15 s after the addition of stimulus, regardless of the dose. We estimate that an occupancy of no more than 20% of the cellular receptors for the stimulus is required to evoke the optimal response. PMID- 6917848 TI - A novel kinin-generating protease (kininogenase) in the porcine anterior pituitary. AB - The purpose of the present study was to determine whether porcine pituitary tissue contains kininogenase activity. Porcine anterior and posterior pituitaries were homogenized in 0.25 M sucrose containing 10 mM Tris/HCl (pH 7.5) and the homogenate subjected to differential centrifugation (10,000 x g for 20 min, then 105,000 x g for 60 min). Fractions were examined for kininogenase activity using canine plasma kininogen as the substrate; kinins were measured by bioassay or radioimmunoassay. The anterior pituitary was found to have kininogenase activity highly concentrated in the 105,000 x g particulate pellet (376 ng of bradykinin generated/mg of protein/h) with little or no activity detectable in other fractions. The porcine posterior pituitary 105,000 x g pellet contained 22% of the kininogenase activity of the anterior pituitary. Anterior pituitary kininogenase activity had a broad pH optimum (pH 7.5-9.0), was heat-sensitive, was inhibited by dithiothreitol, soybean trypsin inhibitor, aprotinin, and diisopropyl fluorophosphate, and was resistant to lima bean trypsin inhibitor, pepstatin, and hirudin. Bradykinin was found to be the principal kinin generated by the anterior pituitary kininogenase as determined by high performance liquid chromatography. The anterior pituitary kininogenase differed from other kininogenases in its sensitivity to inhibitors and substrate specificity. PMID- 6917849 TI - Effect of Met-tRNAf deacylase on polypeptide chain initiation in rabbit reticulocyte lysate. AB - The possible role of Met-tRNAf deacylase in the regulation of protein synthesis in rabbit reticulocyte lysate by the hemin-controlled translational repressor (HCR) or the double-stranded RNA-activated inhibitor (dsI) has been examined. Inhibition of protein synthesis by either HCR or dsI is associated with a marked increase in the steady state level of 48 S initiation complexes, containing a 40 S ribosomal subunit, globin mRNA, and a reduced level of Met-tRNAf, suggesting that the rate of 60 S subunit addition may be inhibited and that subunit-bound Met-tRNAf may become deacylated by Met-tRNAf deacylase. The addition of highly purified Met-tRNAf deacylase to lysate samples incubated with HCR or dsI reduces the [35S]Met-tRNAf labeling of 48 S complexes to even a lower level but has no effect on the high level of [35S]Met-tRNAf associated with 43 S complexes in the plus hemin control. The effect of added deacylase on the labeling of 48 S complexes with [35S]Met-tRNAf can be overcome by adding eIF-5 or a soluble reticulocyte protein that has been termed the reversing factor, but not by the addition of eIF-2. Added deacylase has no effect on the level of mRNA in 48 S complexes or the labeling of these complexes with [35S]fMet-tRNAf. When lysate samples were labeled with Met-tRNAf, purified from wheat germ or yeast, and doubly labeled with 32P at the 5' end and [35S]methionine aminoacylation, HCR reduced the level of 32P and 35S-labeled tRNAMetf in 48 S complexes to a similar degree, suggesting that once it has become deacylated, tRNAMetf dissociates from the 40 S subunit. PMID- 6917850 TI - Activity of epiphyseal cartilage membrane alkaline phosphatase and the effects of its inhibitors at physiological pH. AB - The kinetics of epiphyseal cartilage membrane-bound alkaline phosphatase activity was studied at physiological pH using p-nitrophenylphosphate and pyrophosphate (PPi) as substrates. The effect of three general types of alkaline phosphatase inhibitors was studied on both purified and membrane-bound forms of the enzyme: 1) uncompetitive inhibitors (L-tetramisole and theophylline), 2) competitive inhibitors (phosphate, arsenate, and vanadate), and 3) metal ions (Mg2+, Ca2+, and Zn2+). These studies were aimed at elucidating the physiological role of epiphyseal cartilage membrane alkaline phosphatase. Hydrolytic activity of enzyme at pH 7.5 toward both PPi and p-nitrophenylphosphate was only one-tenth and one hundredth, respectively, of that observed at optimal pH. Arsenate (Ki - 1.0-2.7 microM) and vanadate (Ki = 0.7-1.3 microM) were powerful inhibitors of alkaline phosphatase; phosphate (Ki = 20-50 microM) was inhibitory at levels two orders of magnitude below the concentration in cartilage extracellular fluid. Neither Zn2+, Ca2+, or Mg2+ was inhibitory toward p-nitrophenylphosphate hydrolysis, whereas all three competitively inhibited PPi hydrolysis. The data suggest that formation of poorly hydrolyzable Ca.PPi, Mg2.PPi, and Zn2.PPi complexes was responsible. Inhibition of PPi hydrolysis by Ca2+ occurred at levels within the physiological range. The close similarity in inhibition of both the purified and membrane-bound forms of alkaline phosphatase at pH 7.5 indicates that interaction with the membrane does not significantly alter conformation at the active site. The data obtained suggest that under physiological conditions, cartilage membrane alkaline phosphatase would be essentially inactive as a phosphohydrolase due to its intrinsically weak activity at pH 7.5 and the strong inhibitory effect of physiological levels of phosphate and Ca2+. PMID- 6917851 TI - Initiation of protein synthesis in eukaryotes. Nature of ternary complex dissociation factor. AB - Excessive concentrations of the eukaryotic initiation factor 2(eIF-2).stimulating protein, a factor that catalyzes the formation of binary (GTP.eIF-2) and ternary (GTP.eIF-2.initiator methionyl-tRNA) initiation complexes at physiological Mg2+ concentrations, can cause ternary complex dissociation when the Mg2+ concentration is raised from 0.5 to 5.0 mM. Stimulation of ternary complex formation and dissociation have similar (a) pH optima, (b) metal ion specificity, and (c) sensitivity to phosphorylation of the eIF-2 alpha subunit. The results suggest that ternary complex dissociation is an artifact with no physiological significance. PMID- 6917852 TI - Studies on the mechanism of action of a eukaryotic codon-dependent factor specific for initiator Met-tRNAf and ribosomal 40 S subunits. AB - A putative eukaryotic initiation factor purified from rat liver cytosol promotes the ApUpGp- and Mg2+-dependent, GTP-independent binding of initiator Met-tRNAf to ribosomal 40 S subunits. The isotopically-labeled factor binds specifically to 40 S subunits to form a binary complex which can then bind Met-tRNAf in the presence of ApUpGp. When 60 S subunits are added, an 80 S complex is formed which contains Met-tRNAf but not the factor. The Met-tRNAf bound to 80 S ribosomes reacts quantitatively with puromycin. Purified 40 S subunits exist in the form of monomers and dimers. The factor converts monomers, which appear to contain one molecule of tRNA, to a form that does not contain tRNA and dimerizes readily. Deacylated tRNA inhibits dimerization and, in the presence of the factor, converts dimers to the monomeric form; thus, the factor appears to act in a reversible manner. This protein factor may play a role in the removal of tRNA from 40 S subunits, which could be generated as a consequence of chain termination, a prerequisite to the bindig of Met-tRNAf. PMID- 6917853 TI - Specificity and reactivity of human leukocyte elastase, porcine pancreatic elastase, human granulocyte cathepsin G, and bovine pancreatic chymotrypsin with arylsulfonyl fluorides. Discovery of a new series of potent and specific irreversible elastase inhibitors. AB - The reactivity and specificity of a series of substituted benzenesulfonyl fluorides with human leukocyte (HL) elastase, cathepsin G, porcine pancreatic (PP) elastase, and bovine chymotrypsin A alpha are reported. Benzenesulfonyl fluorides with 2-fluoroacyl substituents were found to be potent and specific inhibitors of elastase. HL elastase was inhibited most rapidly by 2--(CF3CF2CONH) -C6H4SO4F (kobs/[I] = 1700 M-1 s-1) which is slightly better than our best peptide chloromethyl ketone inhibitor of this enzyme. PP elastase was most rapidly inhibited by 2--(CF3CONH)--C6H4-SO2F (kobs/[I] = 2300 M-1S-1). The 2- (CF3CF2CF2CONH) and 2--(CF3SNH) derivatives were quite selective for HL elastase and inhibited PP elastase, cathepsin G, and chymotrypsin A alpha quite slowly. A specific and potent chymotrypsin inhibitor (2--(Z--Gly--NH)--C6H4SO2F) was also discovered. A model for the elastase inhibition reaction is proposed which involves interaction of the fluroacyl group of the inhibitor with the primary substrate recognition site S1 of the enzyme. Hydrogen bonding also occurs between the inhibitor NH and a backbone peptide carbonyl group, probably from residue 214. The 2-fluoroacyl group plays the dual role of binding in the hydrophobic S1 pocket and through electronic effects, increasing the strength f the hydrogen bond. The results of this study demonstrate that it is possible to construct simple organic molecules which are specific inhibitors of HL elastase, PP elastase, or chymotrypsin. PMID- 6917854 TI - Reliability of the MS-2 system in detecting methicillin-resistant Staphylococcus aureus. AB - The MS-2 system (Abbott Diagnostics, Division of Abbott Laboratories, Dallas, Tex.) is an automated system capable of rapid antimicrobial susceptibility testing. However, the short incubation periods used by the device may adversely affect its ability to detect slowly growing resistant organisms. Shortly after the introduction of the MS-2 system into the University of Mississippi Medical Center clinical microbiology laboratory, we noted discrepancies between the MS-2 and the disk diffusion susceptibility reports when methicillin-resistant Staphylococcus aureus isolates were tested. Subsequently, we determined the susceptibilities of 75 such isolates by the MS-2 and Kirby-Bauer disk diffusion methods and measured the minimum inhibitory concentrations of methicillin, oxacillin, and cephalothin for 33 of the 75 isolates by standardized agar dilution techniques. There was only 47% overall agreement between the MS-2 and disk diffusion methods when methicillin was tested and 15% agreement when cephalothin was the test drug. There was 93% or more overall agreement between the two methods when other antimicrobial agents were tested. The minimum inhibitory concentration of methicillin was greater than or equal to 16 micrograms/ml for all 33 isolates evaluated by the agar dilution method. A comparison of the MS-2 and agar dilution results revealed an overall agreement of 49% when the susceptibilities to methicillin were determined. The MS-2 system reported that multiple methicillin-resistant S. aureus isolates obtained from a single patient were either resistant, intermediate, or sensitive to methicillin. Inconsistent results were also obtained when a single isolate was tested simultaneously in 10 cuvette cartridges. We conclude that the MS-2 system does not reliably detect methicillin and cephalothin resistance among S. aureus. PMID- 6917856 TI - Staff development: the problems of motivation. PMID- 6917857 TI - Mandatory continuing education in Kansas - three years later. PMID- 6917855 TI - Purified human plasma kallikrein aggregates human blood neutrophils. AB - Exposure of human blood polymorphonuclear leukocytes (PMN) to purified active plasma kallikrein resulted in PMN aggregation when kallikrein was present at concentrations ranging from 0.4 to 0.6 U/ml (0.18-0.27 microM). Kallikrein induced PMN aggregation was not mediated through C5-derived peptides, because identical responses were observed whether or not kallikrein had been preincubated with an antibody to C5. Moreover, kallikrein was specific for aggregating PMN, because no aggregation was observed with Factor XII active fragments (23 nM), Factor XIa (0.6 U/ml or 15nM), thrombin (1.6 microM), plasmin (2 microM), porcine pancreatic elastase (2 microM), bovine pancreatic chymotrypsin (2 microM), or bradykinin (1 microM). Bovine pancreatic trypsin (2 microM) aggregated PMN, but to a lesser extent than kallikrein (0.18 microM). Kallikrein was a potent aggregant agent for PMN because similar responses were observed with kallikrein (0.5 U/ml or 0.23 microM) and an optimal dose (0.2 microM) of N-formyl-methionyl leucyl-phenylalanine. In addition, PMN incubation with kallikrein resulted in stimulation of their oxidative metabolism as assessed by an increased oxygen uptake. Neutropenia and leukostasis observed in diseases associated with activation of the contact phase system may be the result of PMN aggregation by plasma kallikrein. PMID- 6917859 TI - Spanish language skills for nurses. PMID- 6917858 TI - Determining the learning needs of nursing personnel in nursing homes. PMID- 6917860 TI - Responding on the spot to learner needs: "why did you come?". PMID- 6917861 TI - Methods of teaching - revisited the nominal group process. PMID- 6917863 TI - Notes on continuing education: "Our speaker for tonight". PMID- 6917862 TI - A data-based approach to continuing education. PMID- 6917864 TI - Assessment of family stress. PMID- 6917866 TI - Categories of self-care needs of ambulatory patients with diabetes. PMID- 6917865 TI - Nursing for a new century--a future framework. PMID- 6917867 TI - The community mental health nurse: a new professional role. AB - This review of recent literature explores the similarities and differences between the work of community psychiatric nurses and their mental handicap counterparts. The comparisons which have been made between these groups of nurses are related to the authors' own research studies. These included an observational study of one community mental handicap nursing team and a national survey of all such teams in England and Wales. The importance of trad union membership, the place of the Community Psychiatric Nursing Association and the implications of joint training courses are discussed. The emergence of a new professional role, that of the "community mental health nurse" is discussed and the implications which this might have for the future organization of community psychiatric nursing services is outlined. PMID- 6917868 TI - Attitudes of nursing staff in general medical wards towards activation of stroke patients. AB - The attitudes and motivation of the nursing staff towards activation of stroke patients were studies. Staff members from two experimental wards received an educational programme on stroke. Concurrently the patients on their wards received an individually adapted nursing programme with emphasis on activation. The attitudes of the nursing staff on these wards and on two identical control wards in the same hospital were examined at 3-month intervals with the help of a 24-item questionnaire. There was a significant change in attitudes, judged on a scale constructed from 14 items, among the staff of the experimental wards during a 6-month period. There were also positive changes in individual items such as attitudes to long-term care. Fewer changes were noted among the untrained auxiliaries than among the trained staff. The high rate of turnover, especially among the untrained staff, led to certain difficulties in the collection and interpretation of data. In conclusion, the educational programme and also perhaps, the other activities of the experimental wards seemed to have affected the attitude of the staff to some extent in a positive direction. PMID- 6917869 TI - A descriptive study of pressure sores: the prevalence of pressure sores and the characteristics of patients. AB - A descriptive study was carried out within a public health services area in Sweden in order to determine the incidence of pressure sores in acute and long term care. Methods of prevention, treatment and the characteristics of patients were also noted. The criteria for the assessment of pressure sores were: skin discolouration, epithelial damage and damage to the full thickness of the skin. The data were collected by means of interviews during 1 week in February, 1980. It was found that within the public health services area there was a pressure sore frequency of 4%; i.e. 71 patients of a total of 1776 had pressure sores. Some of these patients had more than one pressure sore; the total number of sores was 109. The methods of prevention and treatment were numerous. The patients who developed pressure sores were predominantly women over 65 years of age, incontinent, and with poor mobility. PMID- 6917871 TI - Educating teachers of nursing: the attitudes of students. AB - One hundred and twenty-four experienced registered nurses representing four status categories (nurse managers, full-time student teachers of nursing, first year part-time student teachers of nursing, and second year part-time teachers of nursing) participated in a study to investigate the nature of their social attitudes. Oliver's Survey of Opinions about Education was used as a measure of social attitudes. The overall conclusion was that the social attitudes of the subjects in the study were more similar than dissimilar. Significant differences were found between the managers and the full time teachers (t = -2.03, P less than 0.05) on radicalism. The teachers were found to be more radical. Significant differences were found between the managers and the first year part-time teachers (t = 2.55, P less than 0.05) on tender-mindedness. The teachers were found to be more tender-minded. Significant differences were also found on tender-mindedness between the managers and the second year part-time teachers (t = -2.37, P less than 0.05). Again, the teachers were found to be more tender-minded than the managers. Apart from these differences, the social attitudes of the subjects were found to be well balanced. When the findings of the present study are compared with other studies relating to the social attitudes of nurses, the pattern which emerges in a more balanced one. However, previous studies mainly used subjects in the 18-21-year age group. The difference in the ages of the subjects is likely to be an important factor on their social attitudes, but further research would be required to determine whether factors other than a difference in ages play a part. PMID- 6917870 TI - Technology and nursing education: a scenario for 1990. AB - An examination of predictions concerning the future of American society provides a basis for building a scenario for nursing education in the USA. Trends influencing the future of society and professional nursing education include the tendency towards a planet-wide society, changing orientations towards individual towns and cities, changes in the occupational structure and in use of energy, and technological breakthroughs in electronics and genetics. Central to new technologies is the computer. Computerized systems of education and networks of such systems are now technically possible. Although capital resources for such systems may be scarce, eventually the substitution of capital for the even more expensive human labour may force the use of greater technology in education. Teacher acceptance is the greatest challenge to increased use of technology in education. Teacher acceptance is the greatest challenge to increased use of technology in education. Increased use of technology may force better instruction. Increased technology does not presuppose a less humanistic education. PMID- 6917872 TI - Janforum: a future framework for nursing: a transcultural perspective. PMID- 6917873 TI - Isolation and partial characterization of an elastase-type protease in human vulva fibroblasts: its possible involvement in vulvar elastic tissue destruction of patients with lichen sclerosus et atrophicus. AB - A complete disappearance of orcein positive material was observed in the superficial dermis of patients suffering from Lichen sclerosus et atrophicus. An elastase-type protease was isolated and partially purified from Triton X-100 extracts of human vulvar fibroblasts by gel permeation chromatography. It presents the characteristics of a metalloenzyme hydrolyzing Succinoyl-tri-alanine paranitroanilide maximally at pH 8.0 and is also active towards insoluble elastin. When partially purified enzyme is directly applied on to rabbit skin sections or when injected intradermally to young rabbits, it produces appreciable degradation of elastic fibers. The involvement of this protease in the disappearance of elastic fibers in Lichen sclerosus et atrophicus is postulated. PMID- 6917874 TI - Bacteremia due to methicillin-resistant Staphylococcus aureus. AB - During a three-year period, Staphylococcus aureus phage type D11/83A/85 that was resistant to methicillin, cephalothin, and multiple aminoglycosides was recovered from 260 infected patients in an urban general hospital in Cincinnati, Ohio. This methicillin-resistant S. aureus (MRSA) was recovered from 30% of all blood cultures positive for S. aureus and represented 50% of all episodes of nosocomial bacteremia due to S. aureus. Bacteremia due to MRSA occurred most often in surgical patients (especially burn patients), occurred late in hospitalization, and was recovered frequently from wounds and intravascular catheters. Infection with S. aureus was the direct cause of death of 44% of the patients with bacteremia due to MRSA. Nine of 10 MRSA-infected patients who were treated with vancomycin alone responded to therapy compared with seven of 15 who were treated with other antistaphylococcal antibiotics (P less than 0.05). The present study defines the epidemiologic characteristics of bacteremia due to MRSA, demonstrates the virulence of MRSA, and proves that vancomycin is effective as therapy. PMID- 6917875 TI - Defensive communication. PMID- 6917876 TI - Nurse staffing in a decentralized organization: part II. AB - It must be emphasized that none of the steps described in this planning process emerged overnight. Rather, they were achieved through a process of evolution, sometimes through trial and error, and always with consultation and participation by many members of the hospital nursing staff. Participation by many in the process of planning for a workable staffing system has been essential to its success. Indeed, creative scheduling by the head nurse is possible because of the way in which the system has been organized. The fact that head nurses are responsible for staffing their own units makes it infinitely easier for them to see what they need to make their units operate effectively and efficiently. Creative scheduling includes the possibility of arranging nurses' hours outside the rigid three-shift schedule used by so many hospitals. Many El Camino nurses now report for work at different hours. In addition, the use of flexible work weeks has proven valuable. Some head nurses now allow for a ten-hour, four-day work week; in emergency staffing situations there have, on occasion, been twelve hour days. Even as this system evolves, it faces change. Just as the requirements for staff cannot be rigid, so must problem solving be flexible and constantly under review. The fact that El Camino believes in constant monitoring of its system is essential to its success. A key philosophical foundation of decentralization is that it must be subject to change. This is no less true in staffing than in other parts of the decentralization structure. By agreeing that change is constant and necessary and that participation is required at all levels of the staffing planning process, we have constructed the outlines of a system that will work in the future as well as it does in the present. Our system centers around the head nurses. It involves their planning; thus it also involves the support of those members of the nursing staff who can provide essential information. But the decisions about how to use the information remain with the head nurse. And that, as much as anything, is at the heart of the decentralized nursing structure. PMID- 6917877 TI - Groupthink: one peril of group cohesiveness. AB - A group's aim is to make well-conceived, well-understood, well-accepted and realistic decisions to reach their agreed-upon goals. This aim applies equally to their own goals and those occasionally imposed by outsiders such as hospital administration, accreditation committees and the federal government. Effective groupwork requires group cohesion with its components of trust, risk taking, mutual support, and group esteem. With constant vigilance the group can maintain its positive dynamics, so that the unhealthy state of groupthink does not undermine its existence. PMID- 6917879 TI - Developing practice-relevant research: a model that worked. PMID- 6917882 TI - The choice of in-hospital or alternative birth environment as related to the concept of control. PMID- 6917880 TI - The mentor connection. AB - The future possibilities for cultivating mentor relationship in nursing are limitless. The mentor system developed more widely in nursing will strengthen the profession by increasing its numbers of competent, successful, and satisfied professionals. Our training in nurturing, as members of a helping profession, coupled with increasing awareness of the benefits of working together can help us to be highly effective mentors. Our individual and collective power and effectiveness in the future will depend to a large extent on our willingness to support each other through strong mentor connections. PMID- 6917881 TI - Prescriptive authority for nurse-midwives. PMID- 6917883 TI - Educational benefits of antepartum continuity of care. PMID- 6917878 TI - Relating nursing staff quality to patients' needs. PMID- 6917884 TI - How the FDA determines the "safety" of drugs: are drugs used in obstetrics really safe? PMID- 6917885 TI - Childbirth experiences of unprepared fathers. PMID- 6917886 TI - Future prospects of nurse-midwifery in the United States. PMID- 6917887 TI - A day in the life of a working mother, nurse and wife. PMID- 6917888 TI - "The shape of the nursing world to come through standards of care". PMID- 6917890 TI - Mental health gives value to life. PMID- 6917889 TI - Health for all by the year 2000: people's health in people's hands. PMID- 6917891 TI - [The effect of aging on the elastase output of PS-test (author's transl)]. PMID- 6917893 TI - [Assistance in child rearing in a family where both parents are deaf-mutes: attitudes of the parents and family members towards the infant, with a focus on hearing perception of the child]. PMID- 6917892 TI - [Assistance of deaf-mute or completely blind patients in delivery and in puerperium]. PMID- 6917894 TI - [At delivery by a patient with split hands and split feet]. PMID- 6917896 TI - [Relationship of artificial rupture of the membrane and the time required for delivery]. PMID- 6917895 TI - [Toward establishment of midwifery profession (2). Organizational unification and future problems. Discussion]. PMID- 6917897 TI - [Blood kallikrein-kinin system in peptic ulcer complicated by gastroduodenal hemorrhage]. PMID- 6917899 TI - [Nursing of patients with esophageal cancer: physiopathology of esophageal cancer]. PMID- 6917898 TI - Elastase activity: the role of elastase in aortic aneurysm formation. PMID- 6917901 TI - [Nursing of patients with esophageal cancer. The nursing process for patients with esophageal cancer]. PMID- 6917900 TI - [Nursing of patients with esophageal cancer. Diagnosis and treatment of esophageal cancer]. PMID- 6917902 TI - [Nursing of patients with esophageal cancer: case study]. PMID- 6917904 TI - [Bedside examination: keypoints in nursing and interpretation of the data. Examination of digestive system diseases (1)]. PMID- 6917903 TI - [Nursing of patients with esophageal cancer. Evaluation of the nursing process: a discussion]. PMID- 6917905 TI - [Nursing study. Interaction with a patient concerned over occupational rehabilitation prior to discharge--assistance in preparation of acceptance of a chronic condition]. PMID- 6917906 TI - [Nursing study. Nursing of a myocardial infarct patient (anteroseptal infarct)--a case study with step analysis of progress in the rehabilitation process]. PMID- 6917908 TI - [Surgery--basis and practice of care. Pneumonectomy. Pre- and post-operative nursing of pneumonectomy patients]. PMID- 6917907 TI - [Assistance of apprehensive patients--for improved communication with patients]. PMID- 6917911 TI - [In search of new nursing philosophy. XVII. A suggestion from a nursing volunteer -from regional geriatric nursing activities]. PMID- 6917910 TI - [In search of humane nursing. Assistance of patients in home nursing]. PMID- 6917909 TI - [Surgery--basis and practice of care. Pneumonectomy. Assistance of a patient with primary lung cancer undergoing pneumonectomy--an aged patient with a consciousness disorder]. PMID- 6917912 TI - [Nursing keypoints. Nursing of hepatectomy patients]. PMID- 6917913 TI - [Medical care based on natural life and its goals]. PMID- 6917914 TI - [Emergency care in food poisonings by naturally poisonous fishes]. PMID- 6917915 TI - [Physiopathology of occupational diseases in rural workers]. PMID- 6917916 TI - [Care of central venous catheters]. PMID- 6917917 TI - [Flow aspiration method of treating a suppurative wound]. PMID- 6917918 TI - [Cryotherapy of acute inflammatory processes in the skin and subcutaneous fat]. PMID- 6917919 TI - [Work of a pressure chamber operator]. PMID- 6917920 TI - [Organization of the laboratory analyses in prophylactic examinations]. PMID- 6917921 TI - [Nurse's work place]. PMID- 6917922 TI - [Urticaria]. PMID- 6917923 TI - [Organization of hygiene education in school]. PMID- 6917925 TI - [Work organization of a pediatric polyclinic registration office]. PMID- 6917924 TI - [Psychotherapy]. PMID- 6917926 TI - [Osteoma of the frontal sinuses]. PMID- 6917927 TI - [Attention to the younger generation]. PMID- 6917929 TI - [Characteristics of the care of patients with head and neck tumors]. PMID- 6917928 TI - [Computation of the days spent by patients in treatment]. PMID- 6917930 TI - [Care of pemphigus patients]. PMID- 6917932 TI - [Health education is an important part of the nurse's work]. PMID- 6917931 TI - [Premature infant. V. Emergency states in premature infants]. PMID- 6917933 TI - [Treatment and prevention of ulcerative gingivitis]. PMID- 6917935 TI - The role and contribution of school nurses. PMID- 6917936 TI - If you suspect drug abuse. PMID- 6917934 TI - [Cement as a metal allergy-inducing agent]. AB - Three groups of patients suffering from eczema, exposed to cement, have been examined. Altogether there were 293 subjects. No particularly strong sensitizing properties of the Polish cement have been found. This, however, calls for confirmation. Differences, hitherto unknown, between masons and concretors have been found at the middle stage of eczema incubation and at middle age when occupational skin lesions occur, indicating a clearly higher allergy risk in concretors. On the other hand the sensitivity to particular metals has been similar in all building workers and did not differ from that in other countries. PMID- 6917937 TI - Role responsibility of the licensed professional nurse. PMID- 6917939 TI - [Rate limitations in the elongation working cycle and the action mechanisms of GTP-complexed elongation protein factors]. AB - Kinetic aspects of the peptide chain elongation process, proper role and the working mechanisms of the GTP-complexed protein elongation factors are discussed. High rates of the codon-dependent binding of aminoacyl-tRNA and translocation are shown to need the mutually exclusive properties of the ribosomal A centre which in the absence of some additional events seems to be unable to possess simultaneously these properties. A centre of translating ribosome is postulated to have a character of dynamic structure providing unsimultaneous consecutive optimization of the aminoacyl-tRNA binding and translocation conditions in accordance with the principle "either binding or translocation". According to this suggestion the rate of elongation is limited by the rate of reversible changes of the A centre structure fitting into the scheme A in equilibrium with B. Each step of this scheme is specifically promoted by corresponding GTP complexed protein factor. Thus, elongation factors are suggested to be specific modulators of the A centre affinity for the codon-appropriate tRNA and to play a role of complex ligands carrying out an allosteric regulation of the ribosomal functional activity. PMID- 6917938 TI - Research and the nurse in community mental health. PMID- 6917940 TI - Merieux inactivated rabies vaccine. Turning the tide against a fatal infection. PMID- 6917941 TI - The total care of a patient in the operating theatre. PMID- 6917942 TI - Trauma and developments in nursing. PMID- 6917943 TI - Medication errors: report errors caused by misleading package labels. PMID- 6917944 TI - Hiatal hernia. PMID- 6917945 TI - Test your knowledge of family centered nursing. PMID- 6917946 TI - Sharing: what Martha wanted. PMID- 6917947 TI - Can Mr. Walton's foot be saved? PMID- 6917948 TI - CEU feature article. From assessment to interventional: how to use heart and breath sounds as part of your nursing care plan. PMID- 6917949 TI - A message from the heart: what isoenzymes can tell you about your cardiac patient. PMID- 6917950 TI - Before you say "data collecting--ugh" read this. PMID- 6917951 TI - When the older patient's apathetic... a problem you can solve. PMID- 6917952 TI - Giving more than dialysis. PMID- 6917953 TI - Hearing aids: handle with care. PMID- 6917954 TI - Deciphering diagnostic studies: thyroid function tests. PMID- 6917956 TI - Pressure sore prevention--aye, there's the rub. PMID- 6917955 TI - Ambulatory nursing: helpful hints for assessing the ostomate. PMID- 6917957 TI - Fear of floating to obstetrics. PMID- 6917959 TI - What makes people bet? PMID- 6917958 TI - The hardest job of all. PMID- 6917961 TI - Safety. Chromic acid mist: is enough guidance given?--2. PMID- 6917960 TI - Counselling: a family problem at work-2. PMID- 6917963 TI - Knowledge of cancer facts among workers following an educational program. PMID- 6917962 TI - Comparison of mental health status of employed and nonemployed mothers with preschool children. PMID- 6917964 TI - Epidemiological research design: utility for the occupational health nurse. PMID- 6917965 TI - Continuing education needs of occupational health nurses. PMID- 6917966 TI - Illinois occupational health nurses express continuing education needs. PMID- 6917967 TI - A breast self-examination program in an occupational health setting. PMID- 6917968 TI - Thoughts on writing and other ponderables. PMID- 6917969 TI - [Participation of the kallikrein-kinin system in microcirculatory disorders in immobilization stress]. PMID- 6917970 TI - [Types of reaction of the blood kallikrein-kinin system in the presence of various functional and pathologic changes in the body]. PMID- 6917972 TI - Bowen's family systems theory as exemplified in Bergman's "Scenes from a Marriage". PMID- 6917973 TI - Genograms: a guide to understanding one's own family system. PMID- 6917971 TI - The child as patient: assessing the effects of family stress and disruption on the mental health of the child. PMID- 6917974 TI - Family therapy with single, young adults. AB - Family therapy with the single, young adult can be successfully carried out using the Bowen family systems theory when the process is staged over time. The therapist who has gone back into his or her own family of origin can be of greatest help as a "coach" to the client in this ongoing process. The therapist assists the client in a process of orderly differentiation that enables the client to develop a more solid sense of self. Reactive distance and emotional cut offs are modified as solutions to anxiety. More personal, flexible family, peer, and work relationships are promoted. The client's initial presenting problems diminish as he/she comes to terms with his/her ultimate aloneness and self responsibility, and begins to accept family members as they are and relationships with them for what they can be. PMID- 6917976 TI - Impressions of nurses working in community health. PMID- 6917977 TI - A psychiatric home care service. PMID- 6917978 TI - [The community health concept: the nurse in community health]. PMID- 6917975 TI - The nucleotide sequence of the maize and spinach chloroplast isoleucine transfer RNA encoded in the 16S to 23S rDNA spacer. AB - The sequence of maize chloroplast tRNAIle2, encoded in the 16S to 23S rDNA spacer, was determined using in vitro labeling techniques. The sequence is: pG-G G-C-U-A-U-U-A-G-C-U-C-A-G-U-Gm-G-D-A-G-A-G-C-m22G-C-G-C-C-C-C-U-G-A-U-t6A- A-G-G G-C-G-A-G-m7G-acp3U-C-U-C-U-G-G-T-psi-C-A-A-G-U-C-C-A-G-G-A-U-G-G-C-C-C-A -C-C AOH. This sequence is identical to that predicted from the corresponding gene sequence, after excision of a long intervening sequence (1), but shows the post transcriptional modifications of this tRNA. Furthermore it demonstrates that the excision of the intron occurs after the second base following the anticodon and that this gene, which is over 1000 base-pair long, is transcribed and processed into a mature functional chloroplast-tRNA. The sequence of maize (a monocot) and spinach (a dicot) tRNAIle2 are shown to be identical. PMID- 6917980 TI - Sounding board: on salaries. PMID- 6917979 TI - Why qualitative research in nursing? PMID- 6917981 TI - Stress in nursing students: dispelling some of the myth. PMID- 6917982 TI - Health care in correctional facilities: a nursing challenge. PMID- 6917983 TI - Nursing journal editors. PMID- 6917984 TI - The PATCO problem and nursing: a comparative analysis. PMID- 6917986 TI - The double study method in nursing research. PMID- 6917987 TI - Nursing diagnosis: differentiating fear and anxiety. PMID- 6917988 TI - Facilitating the integration of theory, practice and research in nursing education: a look at one graduate program. PMID- 6917985 TI - End paper: there they go again. PMID- 6917989 TI - Scholarly pursuit of excellence: doctoral education in nursing. PMID- 6917991 TI - Profile - Sheila Collins: striking the right balance. Interview by T Ross. PMID- 6917990 TI - An interpretive approach to clinical nursing research. PMID- 6917992 TI - Crossroads and burials. PMID- 6917994 TI - Nursing research: tell them like it is. PMID- 6917993 TI - Nursing research: towards better care. PMID- 6917995 TI - Centres of excellence. 2. From strength to strength. PMID- 6917996 TI - Postbasic education: update, top-ranking. PMID- 6917998 TI - Coronary care: too good to die. PMID- 6917997 TI - Students' forum - vital signs. 4. Blood pressure. PMID- 6918000 TI - Careers - orthopaedic nursing: the bonus of training. PMID- 6918001 TI - Management forum 2 - at unit level. PMID- 6917999 TI - Ulcerative colitis: never give up hope. PMID- 6918002 TI - They are not silly, frilly or starchy! PMID- 6918004 TI - Reorganisation: don't ask me! PMID- 6918003 TI - It's all in a name. PMID- 6918005 TI - Centres of excellence. 3. 'There 's so much going on'. PMID- 6918006 TI - Community nursing - anytown anecdotes. 7. Sorry...what was that? PMID- 6918007 TI - Statistics for nurses. 1. Are your data correct? PMID- 6918008 TI - A long, lonely wait. PMID- 6918009 TI - Hiatus hernia: slip sliding away. PMID- 6918010 TI - Laryngectomy: surgery, therapy and support. PMID- 6918012 TI - Careers - care of the dying: a universal state. PMID- 6918011 TI - Nursing care study - testicular hydrocele: cause unknown. PMID- 6918013 TI - A program of home traction for congenital dislocation of the hip. PMID- 6918015 TI - Musculoskeletal assessment: screening for congenital dislocation of the hip. PMID- 6918014 TI - Setting up portable Bryant traction. PMID- 6918016 TI - An analysis of changes in the children's specialty hospital field, 1964-1979. PMID- 6918017 TI - Effective resume writing. PMID- 6918019 TI - Geriatric medicine. PMID- 6918018 TI - Influence of mevinolin on experimental atherosclerosis in rabbits. PMID- 6918020 TI - Venous and peripheral vascular disease. PMID- 6918021 TI - Noninvasive diagnostic techniques in peripheral and carotid vascular disease. PMID- 6918022 TI - Outpatient oxygen therapy. AB - Patients with polycythemia, pulmonary hypertension, or cor pulmonale are most likely to benefit from home oxygen therapy; in others, exercise tolerance can be improved and neuropsychologic effects of hypoxemia relieved. Indications for home therapy, methods of delivering outpatient oxygen, economic considerations, and possible complications are addressed. PMID- 6918023 TI - Seizure disorders in the elderly. PMID- 6918025 TI - Psychological/cognitive testing in an ambulatory setting. PMID- 6918024 TI - Mental health issues in the elderly. AB - A practical, clinical approach to the diagnosis of depression in the elderly is described, and guidelines are suggested for treatment of depression by pharmacotherapy, electroconvulsive therapy, and psychotherapy, Clinical dementia is reversible in one-fifth of elderly patients with this disorder. For those with irreversible dementias management of the environment and pharmacotherapy are recommended. PMID- 6918026 TI - Otolaryngology in the geriatric patient. PMID- 6918028 TI - Joint replacement in the lower extremities of the elderly. AB - Total hip or knee replacement in elderly patients may be advisable to relieve pain, improve joint motion, and increase the overall function. Indications for hip and knee arthroplasty are outlined and possible complications are addressed. Excellent results using both techniques have been reported in the elderly. PMID- 6918029 TI - Dental problems in the elderly. AB - The lack of adequate oral care is a major problem in the elderly, causing oral and dental conditions that can predispose to nutritional deficiencies, communication difficulties, and devastating dental disease. Good oral hygiene, especially in hospitalized, chronically ill patients, is emphasized to prevent oral infection and periodontal disease. PMID- 6918027 TI - Ophthalmic surgery in the elderly. PMID- 6918030 TI - Physical activity and aging. PMID- 6918031 TI - Rehabilitation of the geriatric patient. Stroke rehabilitation, the rehabilitation team, and the usefulness of functional assessment. AB - Salient features of rehabilitation in the elderly are illustrated through the case history of a stroke patient. The efforts of the multidisciplinary rehabilitation team and the consideration of alternative settings and levels of care are critical factors in the restoration and preservation of function in the elderly. Systematic functional assessment, using instruments such as the Barthel index, is recommended to document patient outcomes. PMID- 6918032 TI - Preventive geriatric medicine. PMID- 6918033 TI - Geriatric gynecology. AB - The quality of life of the postmenopausal woman can be significantly improved by active investigation and treatment of gynecologic disorders, such as postmenopausal osteoporosis, in this age group. Surgical intervention should never be excluded simply on the basis of chronologic age. PMID- 6918034 TI - Geriatric sexuality. PMID- 6918035 TI - Urologic considerations in the elderly. AB - The impact of urinary tract infections, incontinence, impotence, and malignant lesions of the urinary tract on the elderly is discussed. A palliative approach is often beneficial in this population; indications for urologic surgery in the elderly should be well-defined in order to maintain quality of life. PMID- 6918036 TI - The aging heart. Problems and management. PMID- 6918037 TI - R.N. bargaining units: multi-hospital systems. Case in point: Presby.-St. Luke's Med. Ctr. v. NLRB (653 F. 2d 450 - MO). PMID- 6918038 TI - Legal case briefs for nurses. N.Y.: mastectomy: issue of informed consent. LA: mastectomy: nursing care complaint. PMID- 6918039 TI - Non-feasance: a common form of malpractice. Case in point: Bell v. Western Pa. Hospital (437 A. 2d 978 - PA). PMID- 6918040 TI - Parents' views of the response of siblings to a pediatric hospitalization. AB - In this study, parents describe siblings' adjustments to a brother's or sister's hospitalization. The families of children hospitalized for relatively usual, non life-threatening reasons were investigated. The relationship between patterns of sibling participation and family structure and sibling response were explored. Sibling responses were studied through intensive interviews with parents. Interviews were conducted using semistructured interview guides and took place within 24 hours of the child's admission and again from 4 to 6 weeks after the child's discharge from the hospital. Families (N = 59) were divided into those in which siblings participated actively in adjusting to the hospitalization and those in which siblings were passive participants in the adjustment process. Sibling participation was discussed as a function of family structure. Parents reported few negative sibling responses to hospitalization. The quality of sibling response was related to the amount of change experienced. PMID- 6918041 TI - Development of sucking in term infants from birth to four hours postbirth. AB - The development of sucking response was investigated in 30 clinically normal infants from 1 or 5 minutes postbirth until their first feeding 4 hours later. Maximum sucking pressures were measured with a research nipple attached to a portable electronic suckometer. Mean suction (negative pressure) began at 5 Torr at birth, peaked at 103 Torr at 90 minutes, and decreased thereafter to 65 Torr at 4 hours. Expression (positive pressure) began at 12 Torr, rose to 29, and decreased to 25. Mean expression pressures correlated with feeding scale scores, r = +.44(24); p less than .025, but suction pressures did not, r = +.26(24); p less than .1. Normative data were gathered on 10 additional stabilized newborns who had been fed twice successfully. Suction pressures were 96 Torr on Day 1, and 103 Torr on Day 2; expression pressures were 25 and 24 Torr, respectively. These pressures approximate those recorded in newborns between 1 and 2 hours postbirth. PMID- 6918042 TI - The effect of centralized decision-making on work satisfaction among nursing educators. AB - The relationship between work satisfaction and centralization of organizational decision-making was examined using survey data from faculty members at four baccalaureate degree schools of nursing, supplemented by interviews with the deans. In a multiple regression analysis, centralization was a significant predictor of satisfaction (p less than .01), with other relevant variables controlled. In tests for statistical interaction, the effect of centralization on satisfaction did not depend on the strength of faculty members' desires for professional autonomy. The results suggested the potential benefits of changes in organizational decision-making to increase faculty participation. PMID- 6918044 TI - Comments: agreement corrected for chance. PMID- 6918043 TI - Sources of social support related to single-parent functioning. AB - Factors related to successful functioning of single parents have not been identified. In this study, relationships among sources of social support and criterion measures of functioning were examined. To isolate the role of social support, a population was selected that was relatively homogeneous on variables considered important in coping with single parenthood: economic status, educational or vocational opportunities, access to day-care, and length of time as a single parent. A check list and structured interview were administered to 30 unmarried women to determine their sources of social support. Ratings of parenting adequacy and of the preschool child's emotional development and behavior by three professional staff members at the day-care centers were used as criterion measures of functioning. Based on the staff ratings, the adequately functioning group was distinquished from the inadequate one. Significant correlations were found between these staff ratings and one social support variable: support from talking with network the members. Key sources of social support were identified through discriminant analyses. PMID- 6918045 TI - [The nursing process yesterday, today and tomorrow]. PMID- 6918046 TI - [Clinical teaching: its importance in nursing education]. PMID- 6918047 TI - [Nursing care of patients with behavior characterized by manifestations of agitation and aggressiveness]. PMID- 6918049 TI - [Establishing limits as a therapeutic measure in nurse-patient relations]. PMID- 6918050 TI - [Basic nursing care in meningococcal diseases]. PMID- 6918048 TI - [Monitoring of intracranial pressure]. PMID- 6918051 TI - [The use of non-therapeutic patterns of communication in student-patient interactions]. PMID- 6918054 TI - [Teaching pediatric nursing at the graduate level]. PMID- 6918052 TI - [Role of the nursing group in primary health care]. PMID- 6918053 TI - [Maneuver of compression of the cervical groove]. PMID- 6918055 TI - [Social aspects of nursing]. PMID- 6918056 TI - [Profile of the graduate in nursing]. PMID- 6918058 TI - [A new concept of operating room nursing]. PMID- 6918057 TI - Single-dose antimicrobial therapy for urinary tract infections in women. AB - Single-dose antimicrobial therapy for uncomplicated urinary tract inductions in women has been reported and evaluated by several investigators. A review of the results of these studies suggest that amoxicillin, sulfisoxazole, and trimethoprim-sulfamethoxazole are effective single-dose regimens in this setting. These results should not be extrapolated to other populations, such as pregnant women or children, or to other antimicrobial agents. The limited data available suggest that cephalosporins are less effective than the regimens recommended. When the infecting organism is sensitive, failure to eradicate bacteriuria with one of these single-dose regimens may be indicative of a more invasive infection, perhaps in the kidney. PMID- 6918059 TI - [The myth of menstruation and its social repercussions. The midwife's role in demystification]. PMID- 6918060 TI - [Hospital hygiene. Surgical infections]. PMID- 6918061 TI - [Health from day to day. The irrationalities of nursing]. PMID- 6918063 TI - [Interview with Virginia Henderson]. PMID- 6918062 TI - ["Legion" is my name]. PMID- 6918065 TI - [Nursing in Israel: a significant experience]. PMID- 6918064 TI - [Program of the General Board of Directors of Health Services of the Generalidad de Cataluna for the planning of nursing services]. PMID- 6918067 TI - [Organization of nursing service in the Perpignan Hospital Center]. PMID- 6918066 TI - [Education of professionals in nursing]. PMID- 6918068 TI - [Unemployment in Catalan nursing]. PMID- 6918069 TI - [Functions of hospital nursing]. PMID- 6918070 TI - [Care in childbirth]. PMID- 6918072 TI - [Midwives in Catalonia]. PMID- 6918071 TI - [Catalan nursing within the Common Market]. PMID- 6918073 TI - [Experiences in community health]. PMID- 6918074 TI - [Labor problems in the public sector]. PMID- 6918075 TI - [Nursing: a feminine profession]. PMID- 6918076 TI - [Specialty project in maternal-child nursing]. PMID- 6918077 TI - [Diseases of the airways]. PMID- 6918078 TI - [Health needs and nursing]. PMID- 6918079 TI - [At the fringes of nursing. Healers and parapsychological medicine]. PMID- 6918080 TI - [Health from day to day. Investigating the research]. PMID- 6918081 TI - [Diseases with altered pulmonary circulation]. PMID- 6918082 TI - [Social and cultural dimensions of hospital facilities]. PMID- 6918083 TI - [Teaching experience]. PMID- 6918084 TI - [Specialty nursing project in mental health and psychiatry]. PMID- 6918085 TI - [Nursing in Uganda]. PMID- 6918086 TI - [Trauma - physiological shock]. PMID- 6918087 TI - [The nurse in the care of injured patients]. PMID- 6918088 TI - Leadership at work. Too much to do? Use 'mental triage'. PMID- 6918090 TI - Trauma post-op. The real nursing challenge. PMID- 6918089 TI - Sex Q & A. Frank answers to your most delicate patient-counseling questions. PMID- 6918091 TI - To heal a draining wound. PMID- 6918092 TI - A nurse's guide to the care and handling of MDs. PMID- 6918093 TI - Opinion exchange: is it better to know the worst? PMID- 6918094 TI - A 'just in case' guide to postanesthetic recovery for the non-recovery-room nurse. PMID- 6918095 TI - Test yourself: dysrhythmia of the month club. Could you meet this challenge? PMID- 6918096 TI - The fine art of giving a physical: how to assess the ears and test hearing acuity. PMID- 6918098 TI - Adrenal patients, part 3. Bilateral adrenalectomy: post-op dangers to watch for. PMID- 6918097 TI - RN's instant refreshers. Beginning this month: GI studies. PMID- 6918099 TI - New drug breakthroughs of 1981. PMID- 6918100 TI - Legally speaking: does freedom of speech cover staff disputes? PMID- 6918101 TI - Sound off! A different kind of unity. PMID- 6918102 TI - [The nursing service at the 9th Sitting of Public Hospitalization]. PMID- 6918105 TI - [Nursing process and records]. PMID- 6918104 TI - [Nursing care in oncology]. PMID- 6918103 TI - [The interview in the health care process]. PMID- 6918106 TI - [Rectal neoplasms]. PMID- 6918108 TI - [Never neglect an anal lesion]. PMID- 6918107 TI - [Colo-rectal preoperative preparation]. PMID- 6918109 TI - [Preparation of a patient for common proctologic interventions]. PMID- 6918111 TI - [Flagyl]. PMID- 6918110 TI - [Proctoscopy technics]. PMID- 6918112 TI - [Penal responsibility of medical auxiliaries in cases of physical injuries of patients]. PMID- 6918113 TI - [Hemorrhoids]. PMID- 6918114 TI - [Rectal polyps]. PMID- 6918115 TI - [Asthma and occupation]. PMID- 6918117 TI - [Respiratory airways pay a heavy tribute to occupational diseases]. PMID- 6918116 TI - [Extrinsic allergic alveolitis, a little known occupational disease]. PMID- 6918118 TI - [Silicosis]. PMID- 6918119 TI - [Pathology relating to the inhalation of asbestos]. PMID- 6918121 TI - [Respiratory cancers of professional origin]. PMID- 6918122 TI - [Role and education of occupational health nurses]. PMID- 6918120 TI - [Pneumoconioses excluding silicoses and pathology related to asbestos]. PMID- 6918123 TI - [Chronic bronchopneumopathies and occupation]. PMID- 6918124 TI - [Dependence factors]. PMID- 6918125 TI - [From symptoms to diagnosis. Secondary effects of medications in geriatrics]. PMID- 6918126 TI - [Urinary infection in the elderly]. PMID- 6918127 TI - ["Giving life to years more than years to life"]. PMID- 6918128 TI - [In the pond of incontinence of the elderly]. PMID- 6918129 TI - [Recently appeared fever in the elderly]. PMID- 6918130 TI - [What must the nurse do when faced with indisposition in the elderly]. PMID- 6918131 TI - [Foreword: "geriatrics: multiple facets."]. PMID- 6918132 TI - [Confusional syndrome. Management]. PMID- 6918134 TI - [The nurse - medication - patient triangle]. PMID- 6918133 TI - [Oral communication in a geriatric department]. PMID- 6918135 TI - [Evolution, over 10 years, of the population of a geriatric department]. PMID- 6918136 TI - [Volunteers and salaried personnel in geriatrics. Respective use, dangers, future]. PMID- 6918137 TI - [Ambulatory rehabilitation of an elderly patient without any precise medical protocol]. PMID- 6918139 TI - [An experiment in preventing patients from becoming bed-ridden]. PMID- 6918138 TI - [The orthophonist in geriatrics]. PMID- 6918142 TI - [Arterial hypertension: etiopathogenesis]. PMID- 6918143 TI - [Complementary tests in arterial hypertension]. PMID- 6918140 TI - [Being old in a hospice]. PMID- 6918141 TI - [An educational trip to the geriatric hospital of Geneva]. PMID- 6918144 TI - [Arterial hypertension: never neglect it]. PMID- 6918145 TI - [Measuring blood pressure]. PMID- 6918146 TI - [Arterial hypertension and vascular risk factors. Need for a multifactorial approach]. PMID- 6918147 TI - [Non medicinal treatment]. PMID- 6918148 TI - [Avlocardyl]. PMID- 6918149 TI - [Congress of the International Council of Nurses in Los Angeles. 2 days of work for national representatives]. PMID- 6918151 TI - [Directed childbirth--stress test]. PMID- 6918150 TI - [Epidemiology of arterial hypertension]. PMID- 6918153 TI - [Artificial induction of labor]. PMID- 6918156 TI - [Apgar score]. PMID- 6918155 TI - [Natural and/or normal childbirth]. PMID- 6918154 TI - [Peridural anesthesia in obstetrics]. PMID- 6918158 TI - [Role of the pediatric nurse in assuming responsibility of parents in a neonatology department]. PMID- 6918159 TI - [Women and crises of adulthood]. PMID- 6918160 TI - [Unfolding of labor]. PMID- 6918152 TI - [Increased safety thanks to medicalization of childbirth]. PMID- 6918157 TI - [Is the admission in maternity satisfactory?]. PMID- 6918161 TI - [Painful sequellae of utero-adnexial infections and surgical interventions]. PMID- 6918162 TI - [Uterine retroversion and pelvic neuralgia]. PMID- 6918163 TI - [Pelvic neuralgia]. PMID- 6918164 TI - [Endometriosis and pelvic neuralgia]. PMID- 6918165 TI - [Etiology of pelvic neuralgia]. PMID- 6918166 TI - [Celioscopy and pelvic neuralgia]. PMID- 6918167 TI - [Psychosomatic aspects of pelvic pain]. PMID- 6918168 TI - [Pelvic infection and pain]. PMID- 6918169 TI - [The evaluation of 10 years of perinatal prevention]. PMID- 6918171 TI - [Pelvic neuralgia and ovarian dystrophy]. PMID- 6918170 TI - [Role of chronic cervicitis in pelvic pain]. PMID- 6918172 TI - [Institutional organization of psychiatry in quest of an identity]. PMID- 6918174 TI - [Different approaches to social determinants of mental disorders]. PMID- 6918173 TI - [Entering the elementary school before the legal age]. PMID- 6918175 TI - [Familty Therapy]. PMID- 6918177 TI - [Systemic arterial hypertension in chronic lung diseases]. PMID- 6918176 TI - [Dimethylsulfoxide as a vehicle for vasoactive drugs in the treatment of systemic scleroderma]. PMID- 6918179 TI - [Dynamics of kinin system in children with destructive lung diseases]. PMID- 6918178 TI - [Effect of proteases and their inhibitors on duration of survival of animals with experimental peritonitis]. PMID- 6918180 TI - [Blood kallikrein-kinin system in painless forms of ischemic heart disease]. PMID- 6918181 TI - [Changes in the kallikrein-kinin system in chronic hemodialysis patients]. AB - The pre-kallikrein values, kallikrein inhibitors and protamine-splitting activity were determined in patients treated by means of chronic haemodialysis. Frequent use of dialysers leads to significant changes in the pre-kallikrein and kallikrein-inhibitor values. On the other hand the pre-kallikrein value remains unchanged after a single use of the capillary kidneys Hemoflow (Fresenius). A much smaller decrease in the kallikrein inhibitor value is observed than after frequent use of dialysers. In all the patients investigated the total protamine splitting activity remained unchanged. Under these circumstances the inhibition capacity is probably sufficient to guarantee a control with respect to fibrinolysis, blood coagulation and the production of kinine. PMID- 6918182 TI - Phosphorylation of ribosomal proteins as a possible control system for protein synthesis. Binding of Met-tRNAf to 40 S ribosomal subunits. AB - The evidence that protein S6 of rat liver ribosomes is involved in P-site functions and that this protein is the main target of the small subunit for in vivo phosphorylation suggests that S6 phosphorylation may contribute to the regulation of protein synthesis. Therefore, we have studied the activity of small ribosomal subunits with unphosphorylated and phosphorylated protein S6 in Met tRNAf binding. The results described in this paper show that at least under in vitro conditions S6 phosphorylation does obviously not influence the activity of small ribosomal subunits for eIF-2 dependent binding of initiator-tRNA. PMID- 6918183 TI - Modulation of the formation of the human C-3 amplification convertase of complement by polyelectrolytes. AB - Heparin in the fluid phase inhibits generation of the C3 amplification convertase of complement C3b,Bb. The anticomplementary activity requires the presence of O sulfate groups on the molecule and is suppressed when the negative charges of heparin are neutralized with positive charges on polycations. In the absence of heparin, polycations inhibit generation of the cell-bound or fluid phase amplification convertase at final concentrations of 1 to 2 x 10(-8) M for poly-L- lysine 50,000 (PLL). PLL is more active on the D-dependent convertase C3b,Bb than in preventing generation of C3b,B; it does not alter the stabilizing effect of properdin. As for heparin, the major site of the inhibitory action of polycations is on the binding capacity of C3b for B. The low affinity interaction of C3b and B is a privileged site for potential pharmacologic modulation of the amplification convertase of complement by polyelectrolytes. PMID- 6918184 TI - Preparatory information: what helps and why. PMID- 6918185 TI - The dexamethasone suppression test. PMID- 6918186 TI - Port wine stain hemangiomas. PMID- 6918187 TI - Hypertension in pregnancy: pathophysiology. PMID- 6918188 TI - Hypertension in pregnancy: prenatal detection and management. PMID- 6918190 TI - Hypertension in pregnancy: labor, delivery, and postpartum. PMID- 6918189 TI - Maternal position and blood pressure during pregnancy and delivery. PMID- 6918192 TI - Cancer of the prostate. PMID- 6918191 TI - Conducting pre- and postconferences. PMID- 6918193 TI - Cancer of the prostate. Treating metastasis with estramustine phosphate. PMID- 6918194 TI - Youth prostitution. PMID- 6918195 TI - Presumed transfer of hepatitis antibody by blood transfusion to chronic hemodialysis patients. AB - During the winter of 1980 it was noted that some of the patients receiving hemodialysis demonstrated antibody to hepatitis B surface antigen and hepatitis B core antigen. A retrospective study was conducted to determine the number of chronic hemodialysis patients who demonstrated this seroconversion and the reason(s) for the conversion. Because these patients were known to receive numerous blood transfusions during their hemodialysis therapy and the antibody titers were relatively low and continued to diminish until they again became negative, we were led to the suspicion that the passive transfer of antibody was occurring. Eleven of the 12 (91.6%) chronic hemodialysis patients in whom antibody was detected received blood transfusions (packed red cells) during their dialysis therapy. All 11 of these patients received the blood prior to the detection of either the antibodies in their serum. All these patients had negative serologic test results within 1 year. This study indicates that patients who receive blood transfusions, especially numerous transfusions, can passively acquire these hepatitis B markers. PMID- 6918196 TI - Evaluation of treatment for pancreatic exocrine insufficiency in dogs with ligated pancreatic ducts. AB - Clinical evaluations and measurements of maldigestion and malabsorption were made in dogs before and after ligation of pancreatic ducts. Fecal wet and dry weights were 300% greater after duct ligation. Fecal fat excretion of dietary intake increased from 9% to 84%. An indirect test of pancreatic function revealed a disappearance of intestinal chymotrypsin activity. All values tested improved during replacement with 5 ml of enzyme powder/day. Little additional improvement was observed after doubling or quadrupling this dose. Little or no additional improvement was seen with the following additions to enzymes: 30-minute preincubation of enzymes with food, antacids, cimetidine (except high dose), neomycin, or bile acids. Enzymes in uncoated tablets were less effective, unless the tablets were crushed. PMID- 6918197 TI - Hospitals share nursing success stories. PMID- 6918198 TI - Board calls for credentialing center under ANA auspices. PMID- 6918199 TI - On keeping it together while moving ahead. PMID- 6918200 TI - As I see it. It would save dollars and make sense to pay me. PMID- 6918201 TI - As I see it. Revise the bylaws revision, says psych nurse. PMID- 6918203 TI - [Distribution of dust risk factors in cement plants and casting foundries]. PMID- 6918202 TI - Dose response of elastase-induced emphysema in hamsters. AB - Elastase-induced emphysema in hamsters was studied using pulmonary function tests in an effort to develop techniques for determining the effects of air pollutants on the progression of this disease. Single intratracheal injections of 6, 12, or 24 units of porcine pancreatic elastase produced dose-related changes in pulmonary function after 4 wk when compared with sham-injected control animals. Boyle's law end-expiratory volume and residual volume, measured by gas dilution, increased (p less than 0.05) at 12 and 24 units, respectively, whereas vital capacity, determined plethysmographically, and total lung capacity wee increased (p less than 0.05) at all 3 elastase doses. Respiratory system compliance, calculated by a nonlinear least squares regression fit of the deflation pressure volume curve, increased (p less than 0.05) at 24 units only. The multiple-breath nitrogen washout slope (N2 slope) and the single-breath diffusing capacity for carbon monoxide (DLCO) decreased (p less than 0.05) at all 3 doses of elastase. Both histologic and physiologic evaluation showed dose-related pulmonary impairment. It appears, therefore, that as little as 6 units of elastase produces mild emphysema in hamsters, which is detectable by pulmonary function testing. Of these tests, the DLCO and N2 slope were the most effective in detecting the degree of impairment. PMID- 6918204 TI - [Analysis and the respiratory risks in a cement plant]. PMID- 6918207 TI - Location of fat may predict diabetes risk. PMID- 6918210 TI - Rinse procedure simplifies graft preparation. PMID- 6918208 TI - Competency statements reflect achievement, challenge for OR nurses. PMID- 6918206 TI - Comparative in vitro study of SQ26,776. AB - A new monocyclic beta-lactam antibiotic, SQ26,776, was evaluated in vitro against clinical isolates, and its activity was compared with that of other cephalosporins, penicillins, and aminoglycosides. This compound was very active against the majority of the aerobic gram-negative bacilli tested, including 47 multiresistant strains. It had no activity against the gram-positive cocci. It also showed activity comparable to that of moxalactam, ceftazidime, ceftriaxone, thienamycin, and tobramycin. It was superior to mezlocillin. The in vitro activity suggests that SQ26,776 should prove useful in settings in which the most likely pathogens are gram-negative bacilli. PMID- 6918209 TI - A teaching plan for cerebroventricular shunting. PMID- 6918211 TI - Proposed recommended practices for aseptic barrier materials for surgical drapes. From the Recommended Practices Subcommittee AORN. PMID- 6918205 TI - Common R-plasmids in Staphylococcus aureus and Staphylococcus epidermidis during a nosocomial Staphylococcus aureus outbreak. AB - During a 7-month period in 1978 to 1979, 31 patients and personnel at a Kentucky hospital were colonized or infected with a Staphylococcus aureus strain resistant to clindamycin, erythromycin, gentamicin, methicillin, penicillin, and tetracycline. S. epidermidis with similar antibiotic resistance patterns had been isolated in this hospital in the year before the S. aureus outbreak. A 32 megadalton R-plasmid, pUW3626, mediating resistance to penicillin and gentamicin, was present in these isolates and in coisolated S. epidermidis from the same outbreak. By colony hybridization, pUW3626 was homologous to gentamicin R plasmids from staphylococci isolated in other geographic areas. Our studies suggest that the emergency of antibiotic resistance in S. Aureus may result from genetic transfer from S. epidermidis as well as from the interhospital spread of resistant staphylococci. PMID- 6918212 TI - Proposed recommended practices for aseptic barrier materials for surgical gowns. From the Recommended Practices Subcommittee AORN. PMID- 6918214 TI - Proposed recommended practices for inhospital packaging materials. From the Recommended Practices Subcommittee AORN. PMID- 6918215 TI - Continuous ambulatory peritoneal dialysis. PMID- 6918213 TI - Proposed recommended practices for preoperative skin preparation of patients. From the Recommended Practices Subcommittee AORN. PMID- 6918216 TI - What's wrong? An inservice for cardiac arrests. PMID- 6918217 TI - Bones: how to grow new ones. PMID- 6918219 TI - Progesterone-induced inactivation of nuclear estrogen receptor in the hamster uterus is mediated by acid phosphatase. PMID- 6918218 TI - The conversion of human complement component C5 into fragment C5b by the alternative-pathway C5 convertase. AB - The cleavage of human complement component C5 to fragment C5b by the alternative pathway C5 convertase was studied. The alternative-pathway C5 convertase on zymosan can be represented by the empirical formula zymosan--C3b2BbP. Both properdin-stabilized C3 and C5 convertase activities decay with a half life of 34 min correlating with the loss of the Bb subunit. The C5 convertase functions in a stepwise fashion: first, C5 binds to C3b and this is followed by cleavage of C5 to C5b. The capacity to bind C3b is a stable feature of component C5, as C5b also has this binding capacity. Component C5, unlike component C3, does not form covalent bonds with zymosan after activation, and C5 is not inhibited by amines. Therefore C5, although similar in structure to C3, does not appear to contain the internal thioester group reported for C3 and C4. PMID- 6918220 TI - Rapid and substantial lowering of human serum cholesterol by mevinolin (MK-803), an inhibitor of hydroxymethylglutaryl-coenzyme A reductase. AB - Mevinolin (MK-803) is a potent inhibitor of HMG-CoA reductase. After a placebo run-in period, mevinolin 5,15 or 50 mg, or placebo was given twice daily for 7-11 days under double -blind conditions ot 4 groups of 6 normocholesterolemic male volunteers. After 7 days, mean serum cholesterol fell 14%, 25% and 24% on 5, 15 and 50 mg, respectively, which was significantly greater than the fall on placebo (4%) in the case of the two higher doses (P less than 0.01). Serum triglycerides did not change significantly. Mevinolin was generally well-tolerated and there were no serious adverse effects. PMID- 6918221 TI - Primary structure of two distinct rat pancreatic preproelastases determined by sequence analysis of the complete cloned messenger ribonucleic acid sequences. AB - The mRNA sequences for two rat pancreatic elastolytic enzymes have been cloned by recombinant DNA technology and their nucleotide sequences determined. Rat elastase I mRNA is 1113 nucleotides in length, plus a poly(A) tail, and encodes a preproelastase of 266 amino acids. The amino acid sequence of the predicted active form of rat elastase I is 84% homologous to porcine elastase 1. Key amino acid residues involved in determining substrate specificity of porcine elastase 1 are retained in the rat enzyme. The activation peptide of the zymogen does not appear related to that of other mammalian pancreatic serine proteases. The mRNA for elastase I is localized in the rough endoplasmic reticulum of acinar cells, as expected for the site of synthesis of an exocrine secretory enzyme. Rat elastase II mRNA is 910 nucleotides in length, plus a poly(A) tail, and encodes a preproenzyme of 271 amino acids. The amino acid sequence is more closely related to porcine elastase 1 (58% sequence identity) than to the other pancreatic serine proteases (33-39% sequence identity). Predictions of substrate preference based upon key amino acid residues that define the substrate binding cleft are consistent with the broad specificity observed for mammalian pancreatic elastase 2. The activation peptide is similar to that of the chymotrypsinogens and retains an N-terminal cysteine available to form a disulfide link to an internal conserved cysteine residue. PMID- 6918222 TI - Young people, drugs...and others. AB - This paper reviews the emotional and relational difficulties associated with the crisis of adolescence, drug dependence being only one of the possible disorders. The use of drugs, perceived as a temporary self-defence measure in the struggle against a relatively serious state of depression possibly leading to suicide, is often also a form of aggression against the self. In addition, the creation, for example, by television or the supermarkets of artificial neo-needs encourages young people to expect magic, external solutions to their problems. The deficiency of imagination found among young people reflects the inadequacy of the ideals of early childhood (which are totally out of tune with reality). By setting themselves inordinately high goals in compensation, young people exaggerate the exterior ideal demands only to reject them later on because they are unattainable. The author argues against the setting up of primary prevention agencies specializing in the problems of adolescence and argues the case for positive primary preventive action in the field of health. PMID- 6918223 TI - Some reflections on the present situation of drug abuse among young people. AB - Interest in drug abuse has recently increased in Denmark and other Scandinavian countries, in particular with regard to certain aspects of the problem. This paper reviews the questions of voluntary versus compulsory treatment, the high death rate among young drug-dependent persons and the problems of the young drug dependent woman and her child. Although it is difficult to predict future developments in drug abuse, the paper concludes that ways and means must be found to provide children and young people with a more meaningful life. This will mean tackling the social, economic and psychological situation of those at risk of becoming drug-dependent. PMID- 6918224 TI - Contacts with a Canadian "street-level" Drug and Crisis Centre, 1975-1978. AB - This paper presents the work and functioning of the distress Centre/Drug Centre, an agency in Calgary, Alberta, Canada, which has evolved from a youth-oriented drug centre to a general crisis centre. It is staffed by volunteers who are supported by professional staff, and offers a 24-hour telephone service throughout the week. The paper reviews the continuing evolution of this service, the drugs most frequently noted in contacts involving crisis and suicide attempts, and the role of crisis centres that use volunteers as front-line workers. The years 1975-1978 were a period in which alcohol was the drug most frequently reported to be associated with crisis and attempted suicide. PMID- 6918225 TI - UNESCO experience in relation to the problems of drug use by young people. PMID- 6918226 TI - Information, teaching and education in the primary prevention of drug abuse among youth in Denmark. AB - This paper describes briefly new approaches to drug abuse prevention. The basic principles are discussed in relation to their application in a community-oriented programme. Some details about the education-of-the-educators programmes are given. It is strongly stressed that concerted community action is necessary to bring any of the activities to success. Co-ordination of timing and attitudinal consent are prerogatives for the positive effect of these programmes. PMID- 6918227 TI - Validity and reliability of a high school drug use questionnaire among Mexican students. AB - This study was carried out to ascertain the validity and reliability of data generated through an internationally developed self-administered questionnaire. Data were collected from two student populations in which prevalence of drug use was known (high and low prevalence rates) and information obtained from the questionnaire checked through personal interview. The questionnaire covered both demographic characteristics and drug use items. A total of 474 students were tested and 335 students (70.7 per cent) retested. Although percentages of missing data and inconsistent responses were high, the questionnaire appeared valid and reliable when analysed on a group basis. It was less reliable on an individual basis. In conclusion, it is considered that with minor modifications the questionnaire can be used in the populations studied with enough confidence in validity and reliability to allow comparisons. PMID- 6918228 TI - "Second Step": a good way toward the baccalaureate. PMID- 6918229 TI - Comparable worth: issue of the 80's. PMID- 6918230 TI - Let us revalue work. PMID- 6918231 TI - Collective bargaining: comparable worth. PMID- 6918232 TI - [How to recognize sleep deprivation in your ICU patient and what to do about it]. PMID- 6918234 TI - Epilepsy: teaching children and families about seizures. PMID- 6918235 TI - Cortical resection: a treatment alternative for some epileptic patients. PMID- 6918233 TI - Sleep-wake disorders and what we can do about them. PMID- 6918236 TI - Nursing at the Neuro. PMID- 6918237 TI - Primary nursing: does good care cost more? PMID- 6918238 TI - The CNA connection. The testing service: how it works! PMID- 6918239 TI - Perspective: journal editors interview CNA president on "entry into practice". Interview by Anne Besharah and Claire Bigue. PMID- 6918240 TI - Tell me when you're ready, an open letter to the patient facing death. PMID- 6918241 TI - Diabetic monitoring measures: does practice make perfect? PMID- 6918242 TI - Dropping out and dropping in. PMID- 6918243 TI - The CNA connection. PMID- 6918244 TI - An overview of hospice care. PMID- 6918245 TI - The public's knowledge about cancer. PMID- 6918246 TI - The effects of a patient education course on persons with a chronic illness. PMID- 6918247 TI - Cancer nursing and the law: Tuma revisited. PMID- 6918248 TI - Programmed instruction: cancer care. Cancer prevention. Carcinogenesis I. PMID- 6918249 TI - Sexual counseling and sexual therapy for patients after myocardial infarction. PMID- 6918251 TI - Antenatal care. PMID- 6918250 TI - Antenatal care: what about mother? PMID- 6918252 TI - Antenatal care: what about father? PMID- 6918253 TI - Complement activation in septic shock due to gram-negative and gram-positive bacteria. AB - Whole serum complement (CH50) and C3, C4, and C3PA plasma values were studied in 48 patients: 9 with nonseptic shock; 20 with sepsis; 14 with septic shock caused by gram-negative bacteria; 5 with septic shock caused by gram-positive bacteria. All were compared with a control group of 25 healthy individuals. Determinations were made upon admission and again 48 and 96 h later. No significant differences in complement values were found between the patients with nonseptic shock and the control group. In the patients with sepsis, decreased CH50 (p less than 0.001) and increased C3PA (p less than 0.02) values were observed, while C3 and C4 remained unaltered. In the patients with septic shock, markedly decreased levels of CH50, C3, and C4 were seen (p less than 0.001, and p less than 0.001, and p less than 0.001, respectively) without changes in C3PA levels. There were no differences between septic shock due to gram-negative and gram-positive bacteria, or between patients who died and those who survived. After 96 h, the altered values returned to the normal range. This underlines the transitory activation of the complement system through the classic pathway and suggests its possible role in the pathogenesis of septic shock in man. PMID- 6918254 TI - Teaching care guide for patients undergoing cardiac catheterization. PMID- 6918255 TI - Counterpulsation: external or intra-aortic. PMID- 6918257 TI - The legal liabilities of critical care. PMID- 6918256 TI - Cardiac pacemakers in children. PMID- 6918259 TI - Nursing care plan: care of the critically ill acute renal failure patient. PMID- 6918258 TI - Fibrinolytic therapy: nursing implications. PMID- 6918260 TI - Are you listening? PMID- 6918261 TI - Unusual complications in a patient receiving streptokinase treatment for deep venous thrombosis. PMID- 6918263 TI - EKG of the month. PMID- 6918262 TI - Arrhythmia quiz. PMID- 6918265 TI - Nursing management in critical care units: head nurse as manager. PMID- 6918264 TI - Breathing space: aerosol or intratracheal instillation? PMID- 6918267 TI - The legal liabilities of critical care. PMID- 6918266 TI - Post pump psychosis. PMID- 6918268 TI - Nursing care plan. PMID- 6918270 TI - Home study program. Renal failure: pathophysiology, assessment, and intervention. PMID- 6918271 TI - Your mystery arrhythmia strips. PMID- 6918269 TI - Pediatric problems: diaphragmatic hernia. PMID- 6918272 TI - Are you listening? Septic shock. PMID- 6918275 TI - Retrospective analysis of nursing care for a patient with hemipelvectomy. PMID- 6918274 TI - The legalities of critical care: legal ramifications of understaffing. PMID- 6918273 TI - EKG of the month. PMID- 6918277 TI - Think transmural. PMID- 6918276 TI - Arrhythmia quiz. PMID- 6918278 TI - The patient with an acute aortic dissection: assessment and management. PMID- 6918279 TI - EKG of the month. PMID- 6918281 TI - Meeting the needs of critical care nurses: the simulated cardiopulmonary resuscitation. PMID- 6918284 TI - Pediatric problems: abdominal assessment. PMID- 6918282 TI - A conceptual approach to the electrocardiogram. PMID- 6918280 TI - Drug corner: verapamil hydrochloride (Isoptin, Calan). PMID- 6918283 TI - Nursing management in critical care units. Performance appraisal of staff nurses: Part I. PMID- 6918285 TI - Your mystery arrhythmia strips. PMID- 6918286 TI - Are you listening? Cardiac tamponade. PMID- 6918287 TI - Metabolic acidosis. PMID- 6918288 TI - Preliminary observations on the metabolic responses to exercise in humans, using 31-phosphorus nuclear magnetic resonance. AB - The new non-invasive method of 31P nuclear magnetic resonance (NMR) has been applied for the first time to human muscle. The metabolic response to exercise--a fall in intracellular pH, a fall in phosphocreatine content, and an increase in inorganic phosphate (Pi) content--occurs without any change in ATP content of the exercised muscle. Abnormal spectra occur in two myopathies examined to date: in McArdle's syndrome, pH rises during exercise, in contrast to the normal fall; and, in an unusual mitochondrial myopathy, Pi content is high, relative to phosphocreatine content, and in keeping with an excessive oxygen consumption in this patient. Intracellular pH reflected, in addition, the systemic pH of the subject; the anticipated abnormalities in muscle pH have been observed in association with lactic acidosis, renal failure and hyperventilation. PMID- 6918289 TI - The techniques and uses of intracellular pH measurements. AB - Weak-acid, 31P-nuclear magnetic resonance (NMR) and microelectrode techniques for measuring intracellular pH (pHi) are compared by demonstration of their use in rat liver. The ultimate test of suitability of these methods is the confidence with which they can be used to clarify aspects of metabolic regulation, translocation of substances across biological membranes, and the control of cell pH itself. Though resting pHi in perfused liver is fairly similar with all three techniques, substantial quantitative differences between values obtained with 31P NMR and microelectrodes are revealed after addition of fructose to the perfused liver preparation. The use and limitations of weak-acid methods in determining the mechanism of inhibition of gluconeogenesis from lactate by acidosis and in determining the pH responsiveness of the lactate transporter in the hepatocyte plasma membrane are demonstrated. Microelectrode-derived values of pHi are probably referable to the bulk phase of the cytosol, whereas values from the other two methods are more complex in their interpretation. Microelectrode and NMR methods have the great advantage of being non-destructive, and continuous records may be obtained. PMID- 6918292 TI - The role of altered lactate kinetics in the pathogenesis of type B lactic acidosis. AB - Of the two types of lactic acidosis, Type B is the most difficult to explain in terms of mechanisms of lactic acid accumulation because the tissue hypoxia that accompanies Type A is not present except as a terminal event. The methods of pharmacokinetics show that for lactate to accumulate to an extent that would disturb acid-base balance, either lactate synthesis or lactate removal would have to be increased or decreased, respectively, by about 7-10-fold. To produce lactic acidosis within a few hours, synthesis would have to increase at the same time as clearance decreased. At normal contribution of the liver to the total lactate clearance (30%-40%), a total cessation of hepatic lactate clearance would not result in lactic acidosis without a concomitant rise in the rate of lactate synthesis. Again, to produce an acidosis this increase would have to be about 8 fold at a normal fractional hepatic clearance. The control of hepatic lactate uptake is discussed in the light of the relatively low hepatic extraction of lactate and in relation to to two main models of hepatic drug (lactate) clearance; the 'well-stirred' and 'parallel-tube' models. PMID- 6918295 TI - Neuropharmacology of insects. PMID- 6918290 TI - The role of catecholamines in metabolic acidosis. AB - Catecholamines (noradrenaline and adrenaline) are catabolic hormones secreted during stress. They initiate many metabolic processes including increased production of both ketoacids and lactic acid. Support for a direct participation of these hormones in the development and/or maintenance of ketoacidosis includes: (1) the high incidence of stress (approx. 70%) as a precipitating factor for ketoacidosis; (2) the elevated plasma levels of noradrenaline (norepinephrine) in patients with ketoacidosis; (3) the rise in plasma concentrations of ketone bodies during catecholamine infusion; and (4) the reduction in the incidence of ketoacidosis with beta-adrenergic pharmacological blockade. Support for a direct participation of catecholamines in the development and/or maintenance of lactic acidosis includes: (1) the common association of stress and lactic acidosis; (2) the rise in plasma lactate concentration during adrenaline (epinephrine) infusion; (3) the precipitation of lactic acidosis by adrenaline intoxication and phaeochromocytoma; and (4) the vasoconstrictor effects of catecholamines leading to tissue anoxia and lactic acid production. Thus, in susceptible patients, catecholamines may be principal determinants of whether ketoacidosis and/or lactic acidosis develops. PMID- 6918293 TI - Organic acidurias: approach, results and clinical relevance. AB - More than twenty-five inherited organic acidurias have been identified during the last fifteen years. This remarkable development is due mainly to the introduction of gas chromatography, and gas chromatography combined with mass spectrometry, in paediatric laboratories for metabolic disease. The chemical approach is determined mainly by physical properties of the acid, such as their extractability and volatility. Most progress has been made with extractable acids. The techniques used for derivatization are mentioned, such as trimethylsilylation, methylation and the preparation of asymmetric derivatives for the separation of optical enantiomers. Metabolite patterns may be so characteristic that the underlying enzyme defect can be deduced. Examples are the leucine degradation defects, all encountered in the authors' laboratory: branched chain ketoaciduria; isovaleric acidaemia; 3-methylcrotonylglycinuria; 3 methylglutaconic aciduria; and 3-hydroxy-3-methylglutaric aciduria. These abnormalities are discussed. D-glyceric aciduria is shown as an example of a not yet fully understood organic aciduria. The clinical approach varies. Metabolic acidosis is an indication for organic acid analysis in urine and plasma, but in many defects there is no acidosis, or only a transient one caused by secondary metabolites, such as lactic and 3-hydroxybutyric acids. Gas chromatography is an obligatory routine investigation in screening programmes for inborn errors of metabolism, especially for the examination of acutely ill neonates and premature babies. PMID- 6918294 TI - Energy metabolism and cellular pH in normal and pathological conditions. A new look through 31phosphorus nuclear magnetic resonance. AB - Cellular energetics can be studied non-invasively using 31P nuclear magnetic resonance (NMR). Besides the concentration of the major phosphorus-containing metabolites, enzyme-catalysed fluxes and intracellular pH can be obtained from the NMR measurement. Metabolic acidosis in the ischaemic myocardium has been studied in the perfused rat heart. Comparison of the pH, measured from the position of the inorganic phosphate (Pi) resonance, with the pH obtained from the resonance of 2-deoxyglucose 6-phosphate (accumulated after perfusion with 2 deoxyglucose) demonstrates that cytoplasmic pH values are being obtained. The pH changes during ischaemia are quantitatively related to the glycogen leads to lactate conversion. Preperfusion with insulin enhanced the lactate production but resulted in the maintenance of ATP for a longer period during ischaemia, even though acidosis was enhanced. In acute renal acidosis, the decrease in intracellular pH is smaller than might have been expected, as demonstrated in the perfused rat kidney. The importance of acidosis in relation to renal preservation was examined in human kidneys prior to transplantation. 31P NMR studies on human forearm muscle have been done. The pH changes measured during aerobic and anaerobic exercise demonstrate the importance of glycogenolysis in providing energy for ATP production. In a patient with suspected McArdle's syndrome, 31P NMR was used to detect the lack of glycogenolysis since during both aerobic and anaerobic exercise a pH rise was observed together with the rapid breakdown of phosphocreatine. PMID- 6918291 TI - Metabolic acidosis in the critically ill. AB - The processes that lead to increased blood lactate concentration in shock and critical illness are complex. Although it is widely believed that lactic acidosis develops because of tissue hypoxia and reduced aerobic metabolism, a number of workers have shown that lactate oxidation rate is actually increased. Lactate production is also increased and this is probably the cause of increased blood lactate concentration. The clinical usefulness of lactate estimation in critical illness is also obscure. Suggestions that whole blood lactate concentration is an accurate predictor of the outcome of an episode of shock are unconvincing. At best this method may differentiate between groups of patients. However, the rate of improvement in lactate concentration with intensive resuscitation probably correlates better with survival, and further investigation of this possibility is suggested. PMID- 6918296 TI - Volunteerism and the student nurse. PMID- 6918297 TI - Appraisal of the diabetic patient. PMID- 6918299 TI - An innovative approach to teaching the diabetic diet. PMID- 6918298 TI - Diabetes patient education: from philosophy to delivery. PMID- 6918300 TI - Effect of dihydralazine on the renal kallikrein-kinin system of the rat. AB - Dihydralazine (0.1 mg/kg), injected intravenously into male Sprague-Dawley rats, caused a decrease in mean arterial blood pressure and an increase in renal plasma flow, while urine volume remained unchanged. Dihydralazine had no effect on kallikrein excretion in the urine and on kallikrein activity in the renal cortex. No correlation was found between renal kallikrein and either renal plasma flow or mean arterial blood pressure. The excretion of kinins in the urine rose markedly after the administration of dihydralazine; no correlation between urinary kinins and urinary or renal kallikrein was observed. Dihydralazine had no influence on the kininogen content of blood-free renal cortex. The enzymatic activity of kininase II in renal cortex was not impaired by dihydralazine. It is suggested that the increased formation of kinins within the kidney could be involved in the vasodilating and blood pressure lowering effect of dihydralazine. PMID- 6918301 TI - [Hygienic requirements for children's toys]. PMID- 6918302 TI - [Prevention of allergic complications from drug therapy]. PMID- 6918304 TI - [Manic-depressive (circular) psychosis]. PMID- 6918303 TI - [Chronic pancreatitis]. PMID- 6918305 TI - [Acute intestinal obstruction]. PMID- 6918306 TI - [Organization of the control of cardiovascular diseases in the USSR]. PMID- 6918307 TI - [Transport immobilization]. PMID- 6918309 TI - [Sex education in school]. PMID- 6918308 TI - [Hygiene of sex life (materials for discussions)]. PMID- 6918310 TI - [Organizational experience with a blood donor system without compensation]. PMID- 6918311 TI - [Epidemiology and prevention of brucellosis]. PMID- 6918312 TI - [Hymenolepiasis]. PMID- 6918313 TI - [Clinical aspects, diagnosis and treatment of croup in children with acute respiratory viral diseases]. PMID- 6918314 TI - [Chronic suppurative inflammation of the middle ear in children]. PMID- 6918315 TI - [Effect of industrial chemical factors on specific body functions]. PMID- 6918316 TI - [Diet therapy in hypertension]. PMID- 6918319 TI - [Midwives' tasks in preventing venereal diseases]. PMID- 6918317 TI - [Quality indices of infectious disease prevention]. PMID- 6918318 TI - [Alcoholic psychoses in young people]. PMID- 6918320 TI - [Emergency states in young infants]. PMID- 6918321 TI - ["Full life in old age" (material for discussion)]. PMID- 6918322 TI - [Preparation for a health education talk]. PMID- 6918323 TI - [Complications from intravenous infusions]. PMID- 6918327 TI - [Chronic pneumonia in children]. PMID- 6918325 TI - [Clinical aspects and treatment of lambliasis]. PMID- 6918326 TI - [Method of taking a solution from a closed standard flask]. PMID- 6918324 TI - [Use of honey in treating eye diseases]. PMID- 6918328 TI - A day in the life of a home health nurse. PMID- 6918329 TI - Involvement - a student's view. PMID- 6918330 TI - A new age for aging. PMID- 6918331 TI - Incident in Room 1114. PMID- 6918333 TI - "Do not fold, spindle, or mutilate". PMID- 6918332 TI - The challenge of private duty nursing. PMID- 6918334 TI - Performance appraisal: an overview. PMID- 6918335 TI - Decision to enter nursing. PMID- 6918336 TI - Review of model for professionalism in nursing: Mount Sinai Medical Center of Greater Miami. PMID- 6918337 TI - Two-stage triolein breath test differentiates pancreatic insufficiency from other causes of malabsorption. AB - In 24 patients with malabsorption, [14C]triolein breath tests were conducted before and together with the administration of pancreatic enzymes (Pancrease, Johnson and Johnson, Skillman, N.J.). Eleven patients with pancreatic insufficiency had a significant rise in peak percent dose per hour 14CO2 excretion after Pancrease, whereas 13 patients with other causes of malabsorption had no increase in 14CO2 excretion (2.61 +/- 0.96 vs. 0.15 +/- 0.45, p less than 0.001). The two-stage [14C]triolein breath test appears to be an accurate and simple noninvasive test of fat malabsorption that differentiates steatorrhea secondary to pancreatic insufficiency from other causes of steatorrhea. PMID- 6918338 TI - [Sensitivity testing of chemotherapeutic agents for ovarian and breast cancers- possibilities and limits of different methods and of their application (author's transl)]. AB - Well-defined and individualised chemotherapy of human malignant tumours can be initiated with the aid of sensitivity tests for chemotherapeutic agents prior to treatment. The effectiveness of the specific cytotoxic agent can be determined by sensitivity testing. For these investigations three methods are available at present: 1. a short-term incubation method (biochemical assay). 2. an agar cloning assay as a specific tissue culture method and 3. a heterotransplantation method with transplantation of tumour cells into thymus-aplastic animals. For routine clinical testing only the biochemical short-time assay and the agar colony assay are of practical significance. The test rates and growth rates in the two methods are composed. The in-vitro and in-vivo correlations of sensitivity testing of chemotherapeutic agents and resistance to chemotherapeutic agents in the different test systems show that the accuracy of prediction for the correct positive or correct negative result is 90%. These results are based on retrospective analysis. For the evaluation of the different prediction assays and for the evaluation of the clinical application of these methods only a randomised prospective therapeutic study can give the answers. However, this has not yet been carried out to date. PMID- 6918339 TI - [Carcinomatous meningeosis during cis-platinum treatment of gynaecological cancers (author's transl)]. AB - Two cases of carcinomatous meningeosis are reported. One occurred during cis platinum combination treatment (PAC-scheme) for advanced ovarian carcinoma and one during the same treatment for a carcinoma of the cervix. Both patients showed no neurological problems prior to chemotherapy. The central nervous symptoms developed rapidly following the administration of small doses of cis-platinum (total dose 160 or 300 mg) and could not be controlled. In one case tumour cells were found in the cerebral spinal fluid. The cause of death could have been an unusually toxic reaction to cis-platinum. A thorough neurological examination prior and during chemotherapy with cis-platinum is necessary in order to recognize toxic side effects of the drug as soon as possible. PMID- 6918340 TI - [Morphology and clinic of ovarial teratomas (author's transl)]. AB - This analysis covers 170 patients with teratomas from 1965-1978 in the Department of Obstetrics and Gynaecology of Heidelberg University. Malignant teratomas were found in two patients; in a special case, a "gliomatosis peritonei" was identified. The histological composition, the degree of maturity, grading and clinical staging were compared with regard to the prognosis and for obtaining an optimal therapeutic approach and procedure. Under the condition that an accurate and extensive histological diagnosis is obtained, "conservative surgery" seems to be the optimal therapy in fertile patients. In case of malignant teratoma, radical surgery followed by chemotherapy is imperative. PMID- 6918341 TI - [Diagnosis of the ureteral function pre and after gynaecological radical surgery by means of urokinetogram (author's transl)]. PMID- 6918342 TI - [Radiographic documentation of morphological alterations after vaginal repair (author's transl)]. PMID- 6918344 TI - [The radiofibrinogen test and the fibrinsplit product test in the diagnosis of deep veinous thrombophlebitis during radiotherapy. A contribution to the evaluation for silent acute thrombophlebitis (author's transl)]. AB - The radiofibrinogen test is especially useful for the diagnosis of deep veinous thrombophlebitis in the legs in patients undergoing radiotherapy for gyanecological cancer. In 62 patients, 6 deep veinous thrombophlebitis were observed during 124 radium insertions in conjunction with preventive administration of anti-coagulants. The most important test for the early coagulation physiologic diagnosis of deep leg thrombophlebitis is the test for fibrinogen and fibrinsplit products. A suitable procedure is the Latex agglutination test which is technically uncomplicated. If deep leg vein thrombophlebitis is found by the radiofibrinogen test, the fibrinsplit products always show at least a fourfold increase. PMID- 6918346 TI - [Reflections on generative behavioural theories (author's transl)]. PMID- 6918345 TI - [Influence of age and parity on risks during pregnancy labour and delivery and on the incidence of caesarean section and perinatal mortality (author's transl)]. PMID- 6918343 TI - [Intravesical prostaglandin E2 and placebo in urinary retention after gynaecological surgery (author's transl)]. AB - In a randomized single blind trial we studied the effectiveness of intravesical prostaglandin E2 in the treatment of postoperative urinary retention after vaginal hysterectomy with colposuspension. One group of patients (n = 8) received 1.5 mg prostaglandin E2 in 50 ml 0.9% NaCl on the 9th postoperative day (72 hours after removal of the Foley catheter) and 50 ml NaCl without prostaglandin E2 on the following day. In the second group (n = 12) NaCl was instilled on the first day of treatment and prostaglandin E2 on the following day. Four hours after the instillation of prostaglandin E2 5 out of 8 women were able to void spontaneously, while after the instillation of NaCl spontaneous micturition occurred in only 2 out of 12 women (p less than 0.05). In both groups the average time period until patients were free of residual urine was 4 days after the initiation of therapy. Compared to placebo intravesical prostaglandin E2 is significantly more effective in achieving spontaneous voiding after gynaecological surgery. PMID- 6918347 TI - [Chances of abortion prophylaxis in early pregnancy (author's transl)]. AB - 7870 pregnancies during the years 1964-1970 observed in a cooperative clinical study give the data basis of an exploratory statistical analysis. Here the associations of drugs taken during the first three months of pregnancy with the incidence of early spontaneous abortions before the fifth month are demonstrated. The rates are corrected for time of enrollment. Women having taken antiemetic drugs or preparations containing vitamins or minerals have less abortions than women without intake of these drugs. This is found especially in the presence of early nausea or vomiting and of bleedings in the first trimenon. It is important that these drugs have not been used for the treatment of bleedings. Therefore the takers and the non-takers are comparable. A success of the then usual treatment with female sexual hormones could not be found. The high abortion rates of women treated with tranquilizers cannot be interpreted as a failure of this treatment because of the epidemiological non-experimental character of the study. PMID- 6918348 TI - [Feto-maternal transfusion with severe fetal anaemia. A case report (author's transl)]. PMID- 6918349 TI - [Is the palpation of the female breast a pitfall in the determination of serum prolactin levels? (author's transl)]. PMID- 6918350 TI - [The law and sterilization or permanent contraception (author's transl)]. PMID- 6918352 TI - [Genuine cervical pregnancy. Aetiology, diagnosis and management (author's transl)]. PMID- 6918351 TI - [The problem of relapsing infections after treatment of trichomoniasis vaginalis with solcotrichovac--a randomised double-blind study (author's transl)]. PMID- 6918353 TI - [Is resistance to antibiotics changing? Development of resistance of Enterobactericeae from specimens 1977-1980]. AB - The results of sensitivity testing from the last 4 years of the enterobacteria isolates have been evaluated for ampicillin, cephalothin, gentamicin, and trimethoprim-sulfamethoxazole. There was a remarkable decrease of cephalothin resistant E. coli, proteus mirabilis, and klebsiella strains. The number of strains resistant to ampicillin was only decreased in the case of proteins mirabilis. The resistance frequency to gentamicin was unchanged. In contrast, an increasing number of resistant strains of E. coli and proteins mirabilis was observed with regard to trimethoprim-sulfamethoxazole. PMID- 6918354 TI - A high-molecular mass derivative of trypsin-kallikrein inhibitor for potential medical use. II. Study of inhibitory activity. AB - Three derivatives of poly[alpha-N beta-(2-hydroxyethyl)-DL-asparagine, beta-N alpha-(2-hydroxyethyl)-DL-asparagine] were used as soluble carrier polymers for binding the trypsin-kallikrein inhibitor (TKI). In addition to the parent polymer an anionic derivative with 19.2 mol of carboxyl groups/100 mol of residues and a hydrophobized derivative with 18.0 mol of butyl groups/100 mol of residues were also used. All carriers contained 6.6 mol of 2-(4-aminobenzamido)ethyl residues/100 mol which were used for the binding after diazotation. All derivatives retained a high inhibitory activity toward trypsin and chymotrypsin whereas the effect on kallikrein was substantially reduced. The kinetic constants were estimated under the simplifying assumption, that classical kinetic equations for the enzyme-inhibitor interaction may be applied. The equilibrium dissociation constants (5 X 10(-9) mol/l) and association rate constants (1 X 10(5) l X mol-1 X s-1) with respect to trypsin are unaffected by the two chemical modifications of the carrier. The increase in the equilibrium dissociation constant (compared to native TKI) is probably a result of the decreasing strength of the enzyme inhibitor complex rather than a manifestation of reduced rate of diffusion of the enzyme to the active center of the polymer-bound inhibitor. PMID- 6918355 TI - Effect of different elastase inhibitors on leukocyte elastase pre-adsorbed to elastin. AB - The effect of three elastase inhibitors (MeO-Suc-Ala-Ala-Pro-Val-CH2Cl, eglin c and alpha 1-proteinase inhibitor) on the hydrolysis of [3H]elastin was determined. The low-molecular mass inhibitors inactivated elastase nearly completely, regardless of whether or not the enzyme was adsorbed to its substrate elastin prior to the addition of the inhibitors. In contrast, elastase preadsorbed to elastin was much less sensitive to the inhibitory effect of alpha 1-proteinase inhibitor than the free elastase. PMID- 6918356 TI - Polymorphism of properdin factor B in Japanese. Description of a rare variant and data of association with HLA and C2. AB - Polymorphism of the properdin factor B (BF) was investigated using an agarose gel immunofixation electrophoresis in 487 unrelated healthy adult Japanese who were already typed for HLA-A, -B, -C and C2. Besides the previously reported phenotypes in Japanese (S, FS, and F), a rare heterozygous phenotype (tentatively maned FTS) was observed once. The estimated allele frequencies for BS*S, BF*F, and FB*FT (F Tokyo) were 0.801, 0.198, and 0,001 respectively. The relative electrophoretic mobility of the variant band of type FTS was measured by Dr. G Mauff to be F 0.75. The conversion fragment Bb of the type showed a double-banded pattern. BF hemolytic activity of the FTS individual was at the same level as other phenotypes. Statistical tests for the phenotypic data of BF with HLA-A, -B, -C, and C2 indicated the presence of the following significant associations in Japanese: Aw33-BF*F, A11-BF*S, Aw24-BF*S, B15-BF*F, B17-BF*F, Bw44-BF*F, B7-BF*S, Bw52;-BF*S, BW54-BF*S, BW59-BF*S, Cw3-BF*F, C2*AT-BF*F, and C2*A'-BF*F. PMID- 6918357 TI - HLA typing in a new family with Fletcher factor deficiency. AB - In a nonrelated white family, the Fletcher factor level in the father was 0.41 U/ml and in the mother, 0.30 U/ml (controls, 0.75-1.25 U/ml). One sibling with recurrent epistaxis had a level of 0.012 U/ml, whereas the other without tendency to spontaneous bleeding had levels between 0.75 and 0.32 U/ml. This suggests autosomal recessive transmission with clinical symptoms when the defect is homozygous. HLA antigens were studied to determine whether characters of the histocompatibility system and this defect are linked: we determined that the gene(s) of the disease is (are) not shared on the HLA complex. PMID- 6918358 TI - [Enriching old age: role of the nursing services]. PMID- 6918360 TI - [Ergonomic approach to school activities: from conceptual idea to reality of school ergonomics]. PMID- 6918359 TI - [Therapeutic application of upper digestive endoscopy]. PMID- 6918361 TI - [Aggressiveness of parents in a general pediatric service. Factors favoring aggressiveness]. PMID- 6918363 TI - [Muscular dystrophy]. PMID- 6918362 TI - [Alcohol and pregnancy...alcohol and child. 3]. PMID- 6918364 TI - [Project PRN 76]. PMID- 6918365 TI - [Psychiatric nurses and eels]. PMID- 6918367 TI - [Interview with the president of the AIIC on the subject of "entry into practice" [interview by Anne Besharah and Claire Bigue]]. PMID- 6918366 TI - [Finally a valorized care plan]. PMID- 6918368 TI - [AIIC network: a biannual congress: what is that?]. PMID- 6918371 TI - Factor analysis as a hospital epidemiology tool. PMID- 6918370 TI - High cost nosocomial infections. AB - The average charge per patient due to nosocomial infection for 215 nosocomial infections in 183 study patients was $693. These cost, however, were concentrated in very few patients; 5% of patients accounted for nearly one-third of total charges. The 10% of patients with highest nosocomial infection cost were patients on Medical or Surgical services; these services were utilized in 71% of patients with nosocomial infection and accounted for 86% of the attributable charges. Among the 22 most costly infections, 17 occurred in surgical wounds and lower respiratory tract. Although these sites accounted for 46% of the infections, they resulted in 77% of the total nosocomial infection charges. Patients with a primary diagnosis of injury had particularly costly infections. Combined analysis of these variables revealed two groups for whom nosocomial infections were especially costly: surgical patients who acquired wound infections after injuries, and medical patients with lower respiratory infections. PMID- 6918369 TI - Nosocomial infection control and the smaller hospital--What do we know, what do we do? PMID- 6918372 TI - Coagulase-negative staphylococci. PMID- 6918374 TI - Health visiting and the nursing process. I: Introducing the health visiting process. PMID- 6918373 TI - Cdc guidelines on infection control. PMID- 6918375 TI - Health visiting and the nursing process. II. Putting the health visiting process into practice. PMID- 6918376 TI - How good is professional support following a diagnosis of mental handicap? PMID- 6918377 TI - Developmental dyslexia. PMID- 6918378 TI - Glue sniffing among schoolchildren. PMID- 6918380 TI - The autistic child and his parents. PMID- 6918381 TI - Know your organizations: National Housewives Register. PMID- 6918382 TI - Controversy over clinical competencies. PMID- 6918379 TI - Autistic children and their treatment. PMID- 6918384 TI - Onset of pheochromocytoma syndrome following cessation of cimetidine administration. PMID- 6918385 TI - Hypoxemia following thoracentesis. PMID- 6918387 TI - Catheter- and infusion-related sepsis: the nature of the problem and its prevention. PMID- 6918386 TI - Radiation exposure to nursing personnel from patients receiving diagnostic radionuclides. PMID- 6918383 TI - The effects of biofeedback training on bronchial diameter in asthma. PMID- 6918390 TI - Survey of critical care nursing practice. Part V. Type of equipment and responsibilities of personnel with regard to equipment. PMID- 6918388 TI - Treatment of patients with congestive cardiomyopathy during hospitalization: a case study. PMID- 6918391 TI - Grand rounds in critical care: problems with sleep. PMID- 6918389 TI - Survey of critical care nursing practice. Part IV. Staffing and training of intensive care unit personnel. PMID- 6918392 TI - A study in atrioventricular block. PMID- 6918393 TI - Calcium antagonists in coronary artery disease. AB - The introduction of calcium antagonists has had a significant influence on the management of angina pectoris. Whereas, a beta blocker functions by reducing oxygen demand, the calcium antagonists increase oxygen supply and also decrease oxygen demand. The calcium ion is a vital link in excitation-contraction coupling; the regulation of intracellular calcium levels directly modulates cardiac and smooth muscle function. The three agents currently in use are verapamil, nifedipine, and diltiazem; ony the first two are available by prescription at this time. Although all three are calcium channel blocking agents, they differ in their electrophysiologic effects. Verapamil and, to a lesser extent, diltiazem slow AV nodal transmission and are thus helpful in controlling the ventricular rate in atrial fibrillation. All have a negative inotropic property which may limit their use in patients with advanced left ventricular dysfunction. PMID- 6918394 TI - Intravenous drugs used in treating hypertensive emergencies. PMID- 6918395 TI - Time structuring for hospitalized school-aged children. PMID- 6918396 TI - Epidemiology: first-hand study by community health nurses. PMID- 6918397 TI - Selecting child care. PMID- 6918400 TI - Reye's syndrome: a challenge not limited to critical care nurses. PMID- 6918398 TI - Care of the prepuce in the uncircumcised child: reinforcing nature's laws of health. PMID- 6918399 TI - A short course in breastfeeding. PMID- 6918401 TI - Species identification of coagulase-negative staphylococcal isolates from blood cultures. AB - Coagulase-negative staphylococci generally are not fully identified, are called Staphylococcus epidermidis, and are considered contaminants when isolated from blood cultures. In a cancer hospital during 6 months, 46 patients had multiple blood cultures (mean, 3.1) which yielded coagulase-negative staphylococci. Species identification of these showed that 10 of the 46 (22%) were not S. epidermidis. Similarly, 96 coagulase-negative staphylococci isolated from only one of multiple blood cultures from patients and thought to be skin contaminants were identified. Of 96 of the staphylococci, 14 (16%) of the latter group were not S. epidermidis. Species found included S. haemolyticus, S. hominis, S. warneri, S. simulans, and S. xylosus. Eight isolates of these species were methicillin resistant, and all eight were mannitol fermenters. The results suggest that these species invasively infect cancer patients with the same frequency at which the species colonize. No one species was identified as being more pathogenic than the others. Routine species identification of coagulase negative staphylococci from blood cultures of cancer patients contributed little to management except to occasionally distinguish multiple-episode culture contamination by different species from sustained bacteremia with the same species. PMID- 6918403 TI - A quantification tool for human resources within an education department. PMID- 6918402 TI - Cholesterol-lowering effect of mevinolin, an inhibitor of 3-hydroxy-3 methylglutaryl-coenzyme a reductase, in healthy volunteers. AB - Mevinolin reduces cholesterol synthesis by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase. The safety and effectiveness of this agent was evaluated in a double-blind, placebo-controlled study in 59 healthy men (serum cholesterol 3.88--7.76 mmol/liter) in five centers. Subjects maintained their usual diet and activities. Doses of 6.25, 12.5, 25, or 50 mg twice daily for 4 wk produced mean reductions of total serum cholesterol fo 23--27% [vs. placebo (4%), P less than 0.01]. Mean low density lipoprotein cholesterol fell 35--45%, while high density lipoprotein and very low density lipoprotein cholesterol, and triglycerides were not significantly affected. Mean apolipoprotein B fell 27--34%. 50 mg was not significantly more effective than 6.25 mg. Mevinolin was generally well tolerated, and no serious clinical or laboratory abnormalities occurred. One subject (12.5 mg) was withdrawn because of abdominal pain and diarrhea. These results suggest that if long-term safety can be demonstrated, inhibitors of 3 hydroxy-3-methylglutaryl-coenzyme A reductase are likely to prove useful in the treatment of hypercholesterolemia. PMID- 6918404 TI - Cognitive learning and anxiety in registered nurses in CEU-contingent and noncontingent continuing education courses. PMID- 6918405 TI - Johari's Window as a framework for needs assessment. PMID- 6918407 TI - Notes on continuing education. Second thoughts on needs assessment. PMID- 6918406 TI - Nursing diagnosis--a focus for continuing education. PMID- 6918408 TI - Qualities/characteristics preferred in continuing education instructors. PMID- 6918409 TI - Professional burnout Part I: the concept, sources, and methods of coping with job related stress. PMID- 6918410 TI - Urine flow-back through urinary diversion pouch anti-reflux mechanisms. PMID- 6918411 TI - Self-care of Op-Site--management of a large pressure ulcer at home. PMID- 6918412 TI - Treatment of a yeast infection in one ileostomy patient. PMID- 6918413 TI - Use of the Perry 51 appliance belt ring with a Hollister pouch. PMID- 6918414 TI - Equal pay for equanimity. PMID- 6918415 TI - Feminine masochism as a component of psychoanalytic femininity. PMID- 6918416 TI - Effect of crisis on female sexual identity. PMID- 6918418 TI - Mind the gap. PMID- 6918417 TI - Attitude toward and use of induced abortion among Taiwanese women. PMID- 6918420 TI - Promotion of health for the aged in the family. PMID- 6918421 TI - Integrating advocacy into the gerontological nursing major. PMID- 6918419 TI - Nursing advocacy for the frail elderly. PMID- 6918423 TI - The importance of personal possessions in the lives of the institutionalized elderly. PMID- 6918422 TI - Effects of touch on communication with elderly confused clients. PMID- 6918424 TI - Blood pressure readings and selected parameter relationships on an elderly ambulatory population. PMID- 6918425 TI - Socio-economic factors and their effects on the nutrition and dietary habits of the black aged. PMID- 6918426 TI - Assessing the abused elderly. PMID- 6918427 TI - Anxiety and depression among the elderly. PMID- 6918428 TI - A course description: designing and managing care of the elderly. PMID- 6918429 TI - Labeling of the elderly as mentally ill: a community analysis. PMID- 6918430 TI - Holistic or wholistic health: a philosophy of the practice in gerontological nursing? PMID- 6918431 TI - Does China really have the solution? PMID- 6918432 TI - Nurses' aides in nursing homes: why are they satisfied? PMID- 6918433 TI - Attitudes toward the elderly: a survey of recent nursing literature. PMID- 6918434 TI - The effect of an exercise program on self-care activities for the institutionalized elderly. PMID- 6918436 TI - Methionine sulfoximine in vivo modifies the tRNALys pool of developing rat brain. AB - tRNA was extracted from brains of 3-, 8-, and 18-day-old rats that were injected intracerebrally, 45 min before death, with [3H]methyl methionine or [8 3H]guanosine, and intraperitoneally, 3 h before death, with L-methionine-dl sulfoximine (MSO), a methylation-activating convulsant agent. Although there was no effect of age or of MSO on the per gram yield of tRNA, its specific radioactivity (dpm/A260) was highest at 3 days in both the control and the MSO groups. Age- and MSO-related changes in tRNALys content of the brain tRNA pool were investigated by means of benzoylated DEAE-cellulose (BDC) and reverse-phase chromatography (RPC). BDC chromatography revealed tRNALys species in the brains of the MSO-treated animals that were absent in control brains. Of particular interest was the finding that differences in RPC-5 chromatographic mobility between control and MSO-tRNALys species were abolished by conversion of lysyl tRNA, suggesting that the MSO-elicited change(s) in tRNALys structure involved the binding site(s) for lysine. Two additional findings were made: (a) lysine acceptance by the [3H]methyl-labeled tRNALys purified from brains of the MSO treated animals was higher than that of controls at 18 days; and (b) omission of the BDC chromatographic step accentuated the differences in mobility on RPC-5 columns between tRNALys species of control and MSO-treated animals. Lastly, we found that some tRNALys species of control and MSO-treated brains contained significantly different proportions of N2-methyl guanine and 1-methyl adenine, relative to controls. These MSO-elicited changes in the methyl base content of tRNALys of immature rat brain are the first evidence of an alteration of brain tRNA structure by a centrally acting excitatory agent. PMID- 6918435 TI - Applied behavioral analysis for disturbed elderly patients. PMID- 6918437 TI - Parkinsonism: forgotten considerations in medical treatment and nursing care. PMID- 6918438 TI - Patient education in epilepsy. PMID- 6918439 TI - Dyskinesias: nursing care and surgical intervention. AB - The dyskinesia syndromes are a group of physically, socially and psychologically debilitating diseases. Many patients may be helped through medical management consisting of drugs, physical and speech therapy, and vocational rehabilitation. However, when medical management fails to palliate symptoms, surgical intervention may be the patient's alternative. The ultimate goal of therapy is to lead an improved quality of life. As a neurosurgical nurse, you have an important role in achieving that goal. PMID- 6918441 TI - The aphasic patient. PMID- 6918440 TI - Rage: implied neurological correlates. PMID- 6918442 TI - The neglect syndrome. PMID- 6918443 TI - Nutrition in neuro science. PMID- 6918444 TI - Myasthenia gravis: a nursing approach. PMID- 6918445 TI - Caring for the patient with chemotherapy-induced thrombocytopenia. PMID- 6918446 TI - Oral hygiene for the elderly. PMID- 6918447 TI - Head injuries: your care counts. PMID- 6918448 TI - That's our grandma. PMID- 6918449 TI - [Mother-child relationship in the peri-natal period]. PMID- 6918450 TI - [Past and present customs relating to childbirth. 1. Aspiration for life]. PMID- 6918451 TI - [An interview with Ms. Margaret F. Myles, an authority in British midwifery. Interview by C. Nono]. PMID- 6918455 TI - [Puerperal depression and mental disturbances. Discussion]. PMID- 6918452 TI - [Lessons in research surveys. 1. Methodology and history of research surveys]. PMID- 6918454 TI - [Dissatisfaction with obstetrical care felt by one half of the patients: a report on a nursing survey at health facilities. From the Japanese Nursing Association]. PMID- 6918453 TI - [Disappearance of acceleration of the fetal pulse]. PMID- 6918456 TI - [Changes in the family structure and factors responsible for mental instability of mothers]. PMID- 6918457 TI - [Depression related to pregnancy, delivery, and child rearing - two personality types]. PMID- 6918458 TI - [Nursing of an obstetrical patient who was hospitalized for an extended time for pregnancy toxemia and twin pregnancy and suffered mental distress during the puerperal period]. PMID- 6918459 TI - [Obstetrical care and midwives in Australia and New Zealand]. PMID- 6918462 TI - [Notes on understanding the drug inserts]. PMID- 6918461 TI - [Basis of statistics. (1). The central value and distribution]. PMID- 6918460 TI - [Past and present customs concerning pregnancy and childbirth. 2. Customs related to recognition of the new life]. PMID- 6918463 TI - [Hyperprolactinemia. (1)]. PMID- 6918464 TI - [Fetal monitoring during delivery and interpretation of its data. 2. Interpretation of the fetal heart rate. 1. The fetal heart rate baseline and its variability]. PMID- 6918465 TI - [Sex behavior and sex-related attitude of the modern woman]. PMID- 6918467 TI - [Obstetrical monitoring devices and interpretation of the data. 3. Interpretation of the fetal heart rate. 2. Fetal heart rate: transient deceleration]. PMID- 6918466 TI - [Psychological processes and mental disturbances of expectant and puerperal women]. PMID- 6918468 TI - [Goals and progress in midwifery education]. PMID- 6918469 TI - [Obstetrical nursing and midwifery education in the basic nursing course: the role and goal of each specialty. A discussion]. PMID- 6918470 TI - [Midwifery education in the future]. PMID- 6918471 TI - [Continuing nursing education in the perinatal ward of Tsukuba University Hospital]. PMID- 6918472 TI - [Symptoms associated with menstruation. 1. Menstrual disorders]. PMID- 6918473 TI - [Past and present childbirth customs. 3. The place for childbirth]. PMID- 6918474 TI - [Basic statistics. 2. Analysis of variance]. PMID- 6918475 TI - [Obstetrical monitoring devices and interpretation of the data. 4. Interpretation of the fetal heart rate. 3. Fetal heart rate (FHR) baseline variability]. PMID- 6918476 TI - [The current problems in the practice of midwifery: analysis of normal pregnancy and delivery]. PMID- 6918478 TI - [Activities at the health education class for expectant fathers held at Shakujii Public Health Clinic]. PMID- 6918480 TI - [Study of the time required for delivery: based on the data from the planned delivery at our hospital]. PMID- 6918477 TI - [On Rubin's "Attainment of the Maternal Role: Part I. Processes and Part II. Models and Referrents"]. PMID- 6918479 TI - [A trial at a child care class for education of expectant fathers held at a private hospital]. PMID- 6918482 TI - [The textbooks used at the health education class for expectant mothers: the text revised for the first time in 12 years. 1. The process of revision and the content of the new edition]. PMID- 6918481 TI - [Topics from the current legislation related to nursing]. PMID- 6918483 TI - [The textbooks used at the health education class for expectant mothers: the text revised for the first time in 12 years. 2. Evaluation by public health nurses]. PMID- 6918485 TI - [The past and present of the customs related to pregnancy and childbirth. 4. 2 types of midwives]. PMID- 6918486 TI - [Methods for taking foot prints of newborn infants]. PMID- 6918487 TI - [Premature labor due to bacterial infection]. PMID- 6918488 TI - [Pregnancy and medication. (1)]. PMID- 6918484 TI - [Basis of statistics. (3). Correlation]. PMID- 6918490 TI - [Reconsideration of the hospital environment - a consideration of the noise. Hospital life and noises]. PMID- 6918489 TI - [The basis of nursing learned in clinical training in obstetrics]. PMID- 6918492 TI - [Reconsideration of the hospital environment--consideration of the noise. Care concerning snoring]. PMID- 6918491 TI - [Reconsideration of the hospital environment--a consideration of the noise. Nursing consideration of noises--participation in new hospital planning]. PMID- 6918493 TI - [Bedside nursing. An approach to a child scheduled for laparotomy and to his mother]. PMID- 6918494 TI - [Beside nursing. Assistance in regaining the trust of a child with emotional deprivation due to dwarfism]. PMID- 6918495 TI - [Beside nursing. Nursing of a patient presenting a difficulty in respiratory care following surgery of esophageal varices]. PMID- 6918496 TI - [A study on euthanasia]. PMID- 6918498 TI - [Introduction to the computer. 14. Challenge to the electronic brain of the computer. (1)]. PMID- 6918497 TI - [Smoking among student nurses--a survey on motives for smoking among nurses]. PMID- 6918499 TI - [Physiology and hygienic consideration of smoking. 7. Changes in the blood during smoking]. PMID- 6918500 TI - [Questions and answers on diseases of the liver, gallbladder, and pancrease. 11. Pancreatic cancer]. PMID- 6918501 TI - [Transactional analysis in nursing. 9. Analysis of psychological games (1)]. PMID- 6918502 TI - [Profile of a nurse. Mr. Hitoe Kanai who studies nursing philosophy through folk medicine]. PMID- 6918503 TI - [Aging report: an observation on geriatric care in England. 2. Geriatric care at a model hospital]. PMID- 6918504 TI - [Unforgetable life in Malawi: St. Luke's Hospital]. PMID- 6918505 TI - [Systemic approach in critical care - with special reference to an aged patient with multiple organ dysfunctions who was admitted as an emergency case for the treatment of septic shock]. PMID- 6918506 TI - [Evaluation of nursing care of a critical patient: based on a survey of nursing actions within 24 hours following open heart surgery and the time required for the care]. PMID- 6918507 TI - [Practice of emergency nursing at the ICU: with special reference to 5 drowning victims]. PMID- 6918508 TI - [Systematic approach and the practice of care - a consideration on the ICU environment, with special reference to "ICU syndrome"]. PMID- 6918510 TI - [Half of the mothers are dissatisfied with delivery - compilation of the report on the "Survey on obstetrical nursing at health facilities" (by the Japanese Nursing Association)]. PMID- 6918511 TI - [Bedside nursing. Assistance in self-care of a patient with non-specific complaints - use of transactional anaylsis]. PMID- 6918512 TI - [Bedside nursing. Approach to a patient in the terminal stage of cancer - assistance of the patient in finding the meaning in resisting the disease process]. PMID- 6918513 TI - [Approach to proper hemodialysis for a patient with severe hypotension - a trial in the stepwise approach]. PMID- 6918514 TI - [Study on the nurse's involvement in acceptance of disability by the patient - through the nursing of a 17-year-old man in the acute stage of a cervical cord injury]. PMID- 6918509 TI - [Regional care and home nursing as a support for patients at home]. PMID- 6918516 TI - [Physiology and hygiene of smoking. 8. Smoking and peptic ulcer]. PMID- 6918518 TI - [Transactional analysis used in nursing. 10. Analysis of psychological games (2)]. PMID- 6918515 TI - [Introduction to computers. 15. Challenge to the electronic brain of the computer. (2)]. PMID- 6918517 TI - [Questions and answers on diseases of the liver, gallbladder, and pancreas. 12. Jaundice]. PMID- 6918519 TI - [Profile of a nurse. Ms. Motoko Nakamura who is in charge of an enuresis consulting service at a children's hospital]. PMID- 6918520 TI - [Aging report: an observation of geriatric care in England. 3. The system of social medicine incorporating the care at health facilities and regional health services]. PMID- 6918521 TI - [Impression of life in Malawi. 3. The pediatric ward]. PMID- 6918522 TI - [Characteristics of modern society and neurosis of children: from the viewpoint of psychiatric counseling and psychotherapy]. PMID- 6918524 TI - [Approach to a child who refuses to attend the school and encouragement toward independence - unpretentious approach by a public health nurse]. PMID- 6918523 TI - [Neurotic children and the social environment]. PMID- 6918525 TI - [Approach to a child who expresses expectation, dissatisfaction, and distrust of her mother by refusal of food]. PMID- 6918526 TI - [Nursing of a child with behavior disorder and anorexia nervosa: a trial in improvement of the home environment]. PMID- 6918527 TI - [Psychogenic fever - the implication of its symptoms: the parent-child relationship in the case of a 10-year-old boy]. PMID- 6918528 TI - [Innovation of sleepwear and underwear for a patient who has undergone crossed pedicled skin graft of the femoral region]. PMID- 6918529 TI - [Bedside nursing. Nursing assistance of a child who refused to attend the school: continued to support until he dissociates himself from his mother and independently obtains employment and enrolls at a school]. PMID- 6918530 TI - [Assistance through counseling of a child with enuresis]. PMID- 6918532 TI - [Hospice: a report on the status of terminal care in the United States. 4. The Connecticut Hospice, the oldest hospice in the United States]. PMID- 6918533 TI - [Introduction of computers. 16. From home computers to large computers]. PMID- 6918534 TI - [Physiology and hygiene of smoking. 9. Smoking and the central nervous system]. PMID- 6918531 TI - [On the status of social rehabilitation of patients receiving hemodialysis]. PMID- 6918536 TI - [Transactional analysis used in nursing. 11. Analysis of a human drama. 1]. PMID- 6918535 TI - [Questions and answers on oral (dental) diseases. 1. The functions of the mouth and teeth]. PMID- 6918537 TI - [Profile of a nurse. Ms. Mitsu Furuta who works as a nurse administrator at a hospital in Bangladesh]. PMID- 6918538 TI - [Aging report: an observation on geriatric care in England. 4. History of geriatric care]. PMID- 6918539 TI - [Impression of Malawi. 4. Measles]. PMID- 6918540 TI - [Etiology and differential diagnosis of cor pulmonale]. PMID- 6918541 TI - [Management of exacerbation of acute cor pulmonale]. PMID- 6918543 TI - [Prognosis of cor pulmonale]. PMID- 6918542 TI - [Management of the chronic stage of cor pulmonale]. PMID- 6918544 TI - [Development of cor pulmonale in the aged and its therapy and management]. PMID- 6918545 TI - [Nursing problems concerning patients with cor pulmonale and the total care]. PMID- 6918546 TI - [Support of patients with continued oxygen inhalation therapy and the control of oxygen]. PMID- 6918547 TI - [Extended respiratory care and nursing of patients with cor pulmonale - the current status of patients with cor pulmonale at our hospital and a suggestion for nursing standards]. PMID- 6918548 TI - [Management of daily activities of a patient with cor pulmonale who is frequently being hospitalized]. PMID- 6918549 TI - [Assistance of a cor pulmonale patient with frequent complaints in preparation for discharge]. PMID- 6918551 TI - [On psychological support of patients with cor pulmonale]. PMID- 6918552 TI - [Exercise therapy of patients with chronic obstructive lung diseases]. PMID- 6918553 TI - [Conference: nursing of patients with cor pulmonale who complain a little]. PMID- 6918550 TI - [Management of a patient with cor pulmonale who refuses oxygen therapy due to chronic headache]. PMID- 6918554 TI - [Determination of capacities for ADL and methods of nursing]. PMID- 6918556 TI - [Nursing diagnosis/nursing profile. The use of the patient profile in the care of peptic ulcer patients]. PMID- 6918555 TI - [Nursing diagnosis/patient profile. Patient profile at the outpatient clinic]. PMID- 6918557 TI - [Self management capacity of diabetic patients and nursing support. (2). The status of studies on education of adult diabetics in Japan]. PMID- 6918559 TI - [Evaluation research: assessment of nursing care]. PMID- 6918558 TI - [Stress: from "Behavior concept and the nursing process"]. PMID- 6918560 TI - [Interrelated issues in evaluation and evaluation research: an evaluator's perspective]. PMID- 6918561 TI - [Information management in quality assurance]. PMID- 6918562 TI - [Determining study topics]. PMID- 6918564 TI - [Establishing valid and reliable criteria: a researcher's perspective]. PMID- 6918563 TI - [Interrelated issues in evaluation and evaluation research: a researcher's perspective]. PMID- 6918565 TI - [Establishing valid and reliable criteria: an evaluator's perspective]. PMID- 6918566 TI - [Relationship of findings of clinical research and development of criteria: a researcher's perspective]. PMID- 6918567 TI - [Relationship of findings of clinical research and development of criteria: a nursing service administrator's perspective]. PMID- 6918569 TI - [Perspective on evaluation from the U.S. Department of Health, Education, and Welfare]. PMID- 6918568 TI - [Developing instruments for measurement of criteria: a research perspective]. PMID- 6918570 TI - [Establishing priorities for evaluation and evaluation research: a nursing perspective]. PMID- 6918571 TI - [Establishing priorities for evaluation and evaluation research: a total health care system perspective]. PMID- 6918572 TI - [Clinical training by assigning a multiple number of patients to a team of nursing students]. PMID- 6918573 TI - [On unique functions and professionalism of nursing]. PMID- 6918574 TI - [Topics: illness in 1 out of 9.1 citizens, results of the 1980 National Health Survey]. PMID- 6918575 TI - [News: opening of the 1st Congress of the Japanese Nursing Science Society's symposium on the study on nursing education]. PMID- 6918576 TI - [In search of educational humanity. (2). Definition of "learning"]. PMID- 6918577 TI - [Nursing eye. Development of personality in nursing education]. PMID- 6918578 TI - [Holistic approach in comprehension of the patient. (1)]. PMID- 6918579 TI - [Simulation. 2]. PMID- 6918580 TI - [Nursing education and students dormitories: a thought on so-called devastation of the educational environment]. PMID- 6918581 TI - [Correlation between the contents of high school reports, the results of the entrance examination and the final examination results prior to graduation (1): correlation between the contents of high school reports and the results of the entrance examination at section 1, Nora Prefectural Medical School of Nursing, in the past 4 years]. PMID- 6918582 TI - [Nursing eye. The need for a course on human relationships in nursing education]. PMID- 6918583 TI - [Holistic approach to the patient. 2]. PMID- 6918584 TI - [Correlation between the contents of high school reports, the results of the entrance examination and those of the final examination before graduation in nursing schools. (2) The correlation between the grades in academic courses and those in clinical training for 4 years in Section 1 of the School of Nursing, Nara Prefectural Medical School]. PMID- 6918585 TI - [Current status and overview of the departments of hygiene and nursing in Shizuoka Prefecture high schools]. PMID- 6918586 TI - [Educational plans in a comprehensive nursing course: "nutrition and meals", a unit in nursing technology]. PMID- 6918587 TI - [Thoughts on the basic theory of nursing]. PMID- 6918589 TI - [Nursing seminar conducted by Mr. Okamura: learning for the "care of people of the 21st century"]. PMID- 6918588 TI - [Lessons in daily living for nursing students]. PMID- 6918591 TI - [Nursing eye: nursing education and the understanding of children]. PMID- 6918590 TI - [In search of educational humanity. 3. Changes in educational contents and the disappearance of learning experiences]. PMID- 6918592 TI - [Keypoints in current nursing education and the direction of postgraduate education]. PMID- 6918593 TI - [Current status of postgraduate nursing education in Japan]. PMID- 6918594 TI - [current status of continuing education conducted by the Japanese Nursing Association]. PMID- 6918595 TI - [Current status of continuing nursing education conducted by local health departments and government agencies]. PMID- 6918597 TI - [Future professional plans of 3d-year nursing students in junior medical technology colleges affiliated with national universities]. PMID- 6918596 TI - [Current status of continuing nursing education run by private organizations]. PMID- 6918598 TI - [Holistic approach to the patient. 3]. PMID- 6918599 TI - [In search of educational humanity. (4). The mind and body of children]. PMID- 6918600 TI - [Personal history of a public health nurse]. PMID- 6918601 TI - Possible influence of physical activity on musculoskeletal symptoms of menopausal and postmenopausal women. AB - The significance of this information is especially meaningful in determining nursing interventions that present minimal health risks and would be effective in reducing bone loss and diminish joint, bone, and muscle aches and pains experience by menopausal women. Nurses as role models, health professionals, and individuals can encourage, support, and teach these women to engage in regular physical exercise. Nurses can also become more knowledgeable regarding factors which influence the musculoskeletal symptoms, e.g., exercise program, smoking, heavy chores surrounding homemaking; and occupation by becoming involved in research in these areas and developing specific nursing interventions from the results. As stated above, the development of regular physical exercise habits in young girls and women of all ages could be an alternative solution in preventing and reducing musculoskeletal symptoms experienced during the climacteric period of life. The introduction of exercise regimens and the support of women engaged in regular physical activities could reduce the high cost of prolonged health care and human suffering on managing the consequences of postmenopausal osteoporosis, namely, fractures, immobility, deformities, and even death. PMID- 6918602 TI - An open school for parents. Parent and Child St. Louis. PMID- 6918603 TI - Systems approach. PMID- 6918604 TI - Perinatal factors and the developmental outcome of preterm infants. AB - To determine the developmental outcome of sick preterm infants, a retrospective analysis of 101 preterm infant survivors, cared for a teaching hospital's neonatal intensive care unit, was conducted. Information regarding the one-year developmental outcome was compared with significant perinatal factors: birth weight, gestational age, neonatal mortality index, respiratory distress syndrome (RDS) severity, and high-risk pregnancy factors. Eighteen percent of all infants studied had developmental delays indicating an improved prognosis for preterm infants. Severe RDS survivors had the greatest incidence of developmental delays and the most high-risk pregnancy histories. PMID- 6918605 TI - Patient control during labor. Effects of two types of fetal monitors. PMID- 6918606 TI - [Profile of a nurse. Ms. Nobuko Kadowaki, a hospital nurse who forwards informations on the discharged patients to local public health clinics]. PMID- 6918610 TI - [Diary of a home-visiting nurse: 3 pairs of husbands and wives affected by illness]. PMID- 6918609 TI - [Medical topics: pseudomonas infections]. PMID- 6918608 TI - [Medical episodes: asbestos in the water supply]. PMID- 6918607 TI - [Medical episodes: coffee and pancreatic cancer]. PMID- 6918611 TI - [Statistical file: the number of nursing instructors in various countries]. PMID- 6918612 TI - [Discussion: the concept of basic education in nursing]. PMID- 6918614 TI - [Perspective for 1982]. PMID- 6918613 TI - [A social policy statement by the American Nursing Association (1)]. PMID- 6918615 TI - [Topics at the Executive Committee and Executive Council of the ICM Congress]. PMID- 6918616 TI - [Report on the Academic Meeting of the 19th ICM (International Confederation of Midwives) congress]. PMID- 6918617 TI - [Factors affecting the perinatal mortality]. PMID- 6918618 TI - [Nursing in the European Community: Italy]. PMID- 6918619 TI - [Hospice activities to help the terminal patients at home]. PMID- 6918620 TI - [The level of technology in the basic nursing education and extent of achievement]. PMID- 6918621 TI - [A social policy statement by the American Nursing Association (2)]. PMID- 6918624 TI - [Study on social position and evaluation of nurses in the history of modern Japanese nursing. Chapter 3. Religion and nursing]. PMID- 6918622 TI - [A trial in training of new nurses (2). Introduction to interpersonal relationship during orientation]. PMID- 6918623 TI - [On involvement of instructors in clinical training of nursing students: on repeated clinical training of students]. PMID- 6918625 TI - [Statistical file: composition of hospital nursing personnel in public and private organizations]. PMID- 6918626 TI - [Expectation on the training of new nurses]. PMID- 6918627 TI - [Learning experiences by new nurses]. PMID- 6918628 TI - [A trial in training of new nurses. (1)]. PMID- 6918629 TI - [Nursing in the European Community: Luxembourg]. PMID- 6918631 TI - [Medical episodes. Kaposi's sarcoma among homosexual men]. PMID- 6918630 TI - [Profiles of nurses. Fumiaki and Mitsuko Inaoka who earned master's degrees in nursing in the United States]. PMID- 6918632 TI - [Carotene and lung cancer]. PMID- 6918633 TI - [Diary of a home-visiting nurse. 10. The effects of illness on the family]. PMID- 6918634 TI - [Hospice: part II]. PMID- 6918635 TI - [Report on the conference of Project HOPE (Health Opportunities for People Everywhere]. PMID- 6918637 TI - Gerontology nursing in the 80's. PMID- 6918636 TI - Auto safety in pediatrics: what can the nurse practitioner do? PMID- 6918639 TI - Self Rx: a self-shaping plan. PMID- 6918638 TI - Health promotion and life style change: a focus for nursing students. PMID- 6918640 TI - Standards of mental health nursing practice. PMID- 6918642 TI - [The alcoholic patient and we. On relationship and treatment with the scope of the general hospital. I]. PMID- 6918641 TI - Pediatric hospice program (an innovation in nursing). PMID- 6918643 TI - [Example USA? The "new nurse"]. PMID- 6918644 TI - [The prognosis]. PMID- 6918645 TI - [Healing - a rediscovered dimension]. PMID- 6918646 TI - [Homo patiens]. PMID- 6918647 TI - [The alcoholic patient and we. On relationship and treatments within the scope of the general hospital. II]. PMID- 6918649 TI - [Surgery in developing countries]. PMID- 6918648 TI - [The rats nibble on the plaster cast]. PMID- 6918651 TI - [Use of a nursing plan in team nursing. A discussion. The basis of continuation of nursing plans]. PMID- 6918650 TI - [What are allergies? An analysis of causes, actions and possibilities for their cure]. PMID- 6918652 TI - [Use of a nursing plan in team nursing: what is required of the team for nursing care planning]. PMID- 6918653 TI - [Continuity of the nursing care plan in the nursing team]. PMID- 6918654 TI - [Nursing plan in the medical team: POS as the axis of the physician-nurse communication]. PMID- 6918655 TI - [Temperature and humidity in the space between the body and the bedding. 4]. PMID- 6918657 TI - [Insight into the diversity of life]. PMID- 6918656 TI - [What is nursing? A reflection on the generation gap of American nurses]. PMID- 6918659 TI - [Nursing administration research]. PMID- 6918660 TI - [Nursing education in the future--a task for improvement]. PMID- 6918658 TI - [Development of creativity]. PMID- 6918662 TI - [Teaching and teaching materials--the nucleus of academic training]. PMID- 6918661 TI - [Pre- and postoperative nursing of the aged. (1)]. PMID- 6918665 TI - [Evaluation of the quality of nursing through the nursing record]. PMID- 6918663 TI - [Problems in teaching the nursing process in relation to nursing theories- analysis by systems approach]. PMID- 6918664 TI - [Prerequisites for determination of nursing quality]. PMID- 6918666 TI - [Quality assurance program--American nurses' approach to the "nursing quality"]. PMID- 6918668 TI - [An example in learning by a mutual study format--leadership training by an encounter group]. PMID- 6918667 TI - [Basis of anthropology and intuition]. PMID- 6918669 TI - [Challenge to achieve improvements in nursing administration]. PMID- 6918670 TI - [On the training in community nursing]. PMID- 6918671 TI - [Pre- and postoperative nursing of the aged. (2)]. PMID- 6918672 TI - [Method of teaching problem-solving in basic nursing education--a trial in paper simulation]. PMID- 6918674 TI - [Physiopathology of shock]. PMID- 6918673 TI - [Evaluation of concentrated training--the obstacles in relating classroom learning to clinical training: the causes, background factors and solutions for the future]. PMID- 6918675 TI - [Diagnosis and treatment of shock]. PMID- 6918676 TI - [In search of new nursing philosophy. XVI. "Aging" and its acceptance]. PMID- 6918677 TI - [Keypoints in nursing. Nursing of patients under hemodialysis]. PMID- 6918679 TI - [Nursing process for shock patients]. PMID- 6918678 TI - [Gentleness in nursing and the patient's life]. PMID- 6918680 TI - [Nursing of shock patients: case studies]. PMID- 6918681 TI - [Evaluation of the nursing process: a discussion]. PMID- 6918682 TI - [Studies of the hematologic, hematopoietic, hemostatic, and fibrinolytic systems]. PMID- 6918683 TI - [Study on the care of the extractor on the work table]. PMID- 6918684 TI - [Nursing study: through the care of a highly apprehensive patient with stomach cancer]. PMID- 6918686 TI - [Surgery--basis and practice of care: gastrectomy. Gastrectomy: its methods and keypoints in care]. PMID- 6918685 TI - [Nursing study: the nurse's attitude in interaction with a patient who refuses nursing intervention]. PMID- 6918687 TI - [Surgery--basis and practice of care: gastrectomy. Pre and post-operative care of the patient with gastrectomy]. PMID- 6918688 TI - [Surgery--basis and practice of care: gastrectomy. Care for the prevention of postoperative complications in poor risk patients]. PMID- 6918689 TI - [Nursing of epileptic patients and nursing personnel--through interactions with an epileptic patient with personality changes]. PMID- 6918691 TI - [Nursing of patients with femoral neck fractures. Diagnosis and therapy of femoral neck fractures]. PMID- 6918690 TI - [Nursing of patients with femoral neck fractures. Physiopathology of femoral neck fractures]. PMID- 6918693 TI - [Nursing of a patient with femoral neck fractures: a case study]. PMID- 6918694 TI - [Nursing of patients with femoral fractures. Evaluation of the nursing process - a discussion]. PMID- 6918692 TI - [Nursing of patients with femoral neck fractures. Nursing process for patients with femoral neck fractures]. PMID- 6918695 TI - [Bedside diagnosis: keypoints in nursing and interpretation of diagnostic data. Diagnosis of the digestive system (2) - liver and exocrine pancreas function tests]. PMID- 6918696 TI - [Nursing study. An observation of a schizophrenic patient from the initial encounter to her acceptance of the nursing personnel - a thought on communication recorded in the process record]. PMID- 6918697 TI - [Innovation in the design of a doughnut-shaped cushion to ease pressure pain - for a patient who was ordered bedrest following nephrolithotomy]. PMID- 6918699 TI - [Surgery - basis and practice of care. Supratentorial craniotomy. Pre- and post operative care]. PMID- 6918698 TI - [Surgery - basis and practice of the care. Supra-tentorial craniotomy; the methods and keypoints in nursing]. PMID- 6918700 TI - [Surgery - basis and practice of care. Supratentorial craniotomy. Pre- and post operative nursing of a patient with cancer of the left temporal lobe]. PMID- 6918701 TI - [Assistance of an expectant patient with juvenile diabetes and the nursing personnel]. PMID- 6918702 TI - [In search of new nursing philosophy. XVIII. Euthanasia and its implication for the patient and his family - a viewpoint of health service personnel]. PMID- 6918703 TI - Legal problems in medical practice: cancer and the law of informed consent. PMID- 6918704 TI - Physicians and nurses: roles and responsibilities in caring for the critically ill patient. PMID- 6918705 TI - Communication failure: some case examples. PMID- 6918706 TI - Psychosocial work of a secundigravida in relation to acceptance of her baby. PMID- 6918707 TI - Significant relationships and their impact on childbearing: a review. AB - This review has examined selected literature concerned with the influences of important relationships on the woman's childbearing experiences. THe effects of early childhood relationships with parents and subsequent relationships shared with others during pregnancy are found to be of major significance. Through both the early and adult relationships, the woman's feelings about the adequacy or inadequacy of herself as a mother take form. Within the literature, a dominant theme recurs: Experiences of others as supportive and helpful facilitate childbearing endeavors, while feeling relationships to be distressing or depleting hinders or makes impossible a successful childbearing outcome. Continuing research efforts focused on the woman's experiences of others in relation to her maternity experience is essential if we are to achieve a better understanding of the complexities of motherhood. PMID- 6918708 TI - Pregnancy and childbirth in women with spinal cord injuries: a review of literature. PMID- 6918709 TI - Maternal conceptual set development: identifying patterns of maternal response to chronically ill infant crying. PMID- 6918710 TI - What Maryland nurses say: "the human touch--the nurse". PMID- 6918711 TI - Some aspects of the report on the role and function of the enrolled nursing aide in New South Wales. PMID- 6918713 TI - Continuing education on a regional basis. PMID- 6918712 TI - Drug Information Centre of NSW. PMID- 6918714 TI - Role and function of mental health nurses. PMID- 6918715 TI - 'She's on the way out'. PMID- 6918716 TI - Child auto safety: Part II. PMID- 6918717 TI - Child passenger safety: Part III. PMID- 6918718 TI - Elder abuse detection and reporting. PMID- 6918719 TI - Returning to school. PMID- 6918720 TI - [Periodontal lesion in diabetes mellitus]. PMID- 6918721 TI - [Treatment of periodontal diseases in diabetes mellitus]. PMID- 6918723 TI - [Determination of kidney function in performing angiography]. PMID- 6918722 TI - [Phytotherapy of children with bronchopulmonary diseases]. PMID- 6918724 TI - [Birthmarks]. PMID- 6918725 TI - [Deaf-mutism]. PMID- 6918726 TI - [Nurse's responsibilities in the otolaryngologic office of a pediatric polyclinic]. PMID- 6918727 TI - [Diagnostic error in a wound from a glass fragment]. PMID- 6918728 TI - [Disinfection of eye pipettes for individual use]. PMID- 6918730 TI - [Combined sociotherapy of the mentally ill]. PMID- 6918729 TI - [Eye burns in the home]. PMID- 6918731 TI - [Certification of paramedical workers]. PMID- 6918732 TI - [Problems of specialization for nurses]. PMID- 6918734 TI - [Current technics and rules for performing prophylactic inoculations]. PMID- 6918735 TI - [Health education design of a pediatric polyclinic]. PMID- 6918733 TI - [Premature infant. 6. The most frequent diseases of infants in the 1st year of life]. PMID- 6918737 TI - [Deontology for the nurse]. PMID- 6918736 TI - [Smoking is both harmful and unbecoming for girls]. PMID- 6918738 TI - [Student academic research work is an important link in the training of medical specialists]. PMID- 6918739 TI - [Philately in the educational process]. PMID- 6918740 TI - [Young Guards museum room in a medical school]. PMID- 6918741 TI - [Rehabilitation of patients with the sequelae of eye injuries]. PMID- 6918742 TI - [Effect of arterial hypotension on the eye]. PMID- 6918743 TI - [Alveolitis and its treatment]. PMID- 6918744 TI - [Recognition of pulmonary tuberculosis patients]. PMID- 6918745 TI - [Intensive combined therapy of pulmonary tuberculosis]. PMID- 6918746 TI - [Protracted course of acute pneumonias]. PMID- 6918747 TI - [Diffuse fibrosing alveolitis]. PMID- 6918749 TI - [Pulmonary tuberculosis and diabetes mellitus]. PMID- 6918748 TI - [Sleep disorders]. PMID- 6918753 TI - [Organization of prophylactic fluorographic examinations]. PMID- 6918751 TI - [Switching installation for electrocardiography]. PMID- 6918752 TI - [Backing electrodes]. PMID- 6918750 TI - [Phytotherapy of peptic ulcer]. PMID- 6918754 TI - [Psychotherapeutic support of probe procedures]. PMID- 6918755 TI - [Nutrition of oncological patients]. PMID- 6918756 TI - [Work of the registrar nurse in a sanatorium-preventorium]. PMID- 6918757 TI - [Health protection: an important link in the work of a shop health service]. PMID- 6918758 TI - [Work of the nurse in the intensive therapy unit]. PMID- 6918759 TI - [Taking of drugs internally]. PMID- 6918761 TI - [Therapeutic properties of sea buckthorn]. PMID- 6918760 TI - [Use of bee honey in medicine]. PMID- 6918763 TI - [Effect of smoking on the cardiovascular system]. PMID- 6918764 TI - [Hemoptysis and hemorrhages in tuberculosis]. PMID- 6918762 TI - [Cancer of the corpus uteri]. PMID- 6918765 TI - [Tuberculous pleurisy]. PMID- 6918766 TI - Preparation of human factor D of the alternative pathway of complement. PMID- 6918767 TI - Bovine and human plasma prekallikrein. PMID- 6918768 TI - Human factor XII (Hageman factor). PMID- 6918769 TI - Primary structure of insoluble elastin. PMID- 6918771 TI - Professional nursing responsibilities and hospice care. PMID- 6918770 TI - Antibodies to insoluble and solubilized elastin. PMID- 6918772 TI - The influence of analgesia in labour on the baby. PMID- 6918773 TI - Genetic counselling and reproductive patterns. PMID- 6918774 TI - About the heartburn of pregnancy. PMID- 6918775 TI - A policy for dental health. PMID- 6918776 TI - The RCM--the first 100 years: where do we go from here? PMID- 6918777 TI - Favourable reaction to male midwives. PMID- 6918778 TI - Male midwives-time to allow them freedom to practise? PMID- 6918779 TI - Breast feeding-a lost art? PMID- 6918780 TI - Early breast feeding management in Denmark and Sweden. PMID- 6918782 TI - The nurse will see you now: 1981 AJN Writing Award. PMID- 6918781 TI - Nursing research being conducted at the University of Missouri-Columbia School of Nursing. PMID- 6918783 TI - One theatre team's experiences of pre- and post-operative visits. PMID- 6918784 TI - The wearing of wedding rings in the operating department. PMID- 6918785 TI - The theatre nurse in the future. PMID- 6918786 TI - Psychiatric liaison nursing service meeting patient, family and staff needs in General Hospital. PMID- 6918787 TI - Walking for aerobic power. PMID- 6918788 TI - Final report of the task force on entry into nursing practice. PMID- 6918790 TI - "Solo" hemodialysis. PMID- 6918789 TI - Individualized instruction for the chronic renal failure client. PMID- 6918792 TI - Renal nursing rounds. PMID- 6918791 TI - Hemodialysis in the U.S.S.R. Bokkins Hospital, Moscow. PMID- 6918793 TI - Nephrology nutrition notes. Cookbooks for the dialysis family. PMID- 6918794 TI - Patient education - sometimes on Sundays. A how-to guide for program planning. PMID- 6918797 TI - Helping students help themselves. PMID- 6918795 TI - [Problems of antibiotic therapy in otorhinolaryngology]. PMID- 6918798 TI - Adding life to years: remotivating elderly people in institutions. PMID- 6918796 TI - Nurses as news. PMID- 6918799 TI - The nurse-detective in American movies. PMID- 6918800 TI - The development and demonstration of an articulation model. PMID- 6918801 TI - Establishing a research subcommittee in a service institution. PMID- 6918802 TI - Alternative community placements for students: school - a good place to learn. PMID- 6918803 TI - Alternative community placements for students: the challenge of day-care centers. PMID- 6918804 TI - Role diversity of nursing administrators: an obstacle to effective leadership? PMID- 6918805 TI - NLN position statement on nursing roles - scope and preparation. PMID- 6918806 TI - NLN position statement on educational mobility. PMID- 6918809 TI - The relationship between patient satisfaction with nursing care and the ability to identify the primary nurse. PMID- 6918807 TI - Revised policies and procedures delineated fron implementation of accreditation study recommendations. PMID- 6918808 TI - The community as client in planning for continuity of care. PMID- 6918810 TI - Selecting a journal for your manuscript. PMID- 6918811 TI - Critical reading. PMID- 6918813 TI - The instructor's responsibility in reducing patient stress. PMID- 6918814 TI - Creativity. PMID- 6918812 TI - Potential advantages and hazards of nontraditional education for nurses. PMID- 6918816 TI - Mount Sinai's distinctive nursing department. PMID- 6918817 TI - On the scene: quality control circles at Barnes Hospital. PMID- 6918815 TI - Determining creativity strategies for a nursing service department. PMID- 6918818 TI - On the scene: Barnes Hospital. An administrator looks at circles. PMID- 6918819 TI - On the scene: Barnes Hospital. Managers look at circles. PMID- 6918821 TI - The use of EMTs--a creative approach to the nursing shortage. PMID- 6918822 TI - Pills on wheels--an innovative nursing study. PMID- 6918824 TI - The nurse noose game. PMID- 6918820 TI - On the scene: Barnes Hospital. How it works for us: panel discussion by circle leaders. PMID- 6918823 TI - Nursing administration's role in establishing a creative climate. PMID- 6918825 TI - An innovative approach to the nursing process. PMID- 6918826 TI - Measuring productivity through patient classification. PMID- 6918828 TI - Teaching crisis creatively. PMID- 6918827 TI - Skilled clinical knowledge: the value of perceptual awareness. PMID- 6918829 TI - Data collection instruments: sidestepping the pitfalls. PMID- 6918830 TI - RN re-entry programs: programmatic and personal considerations. PMID- 6918832 TI - Monitoring lithium to detect toxicity. PMID- 6918834 TI - Test your knowledge of fluid and electrolyte management--part 1. PMID- 6918833 TI - Acute poststreptococcal glomerulonephritis. PMID- 6918831 TI - Medication errors: always check the tubing when you use an infusion controller. PMID- 6918836 TI - New drugs. PMID- 6918837 TI - Polypathia -not personality- caused our problems with Leon. PMID- 6918838 TI - Trach care? Take care--infections's on the prowl. PMID- 6918839 TI - CEU feature article: if patient teaching tries your patience, try this plan. PMID- 6918840 TI - Providing better emergency care when behaviors bar the way. PMID- 6918835 TI - Sharing: learning from experience. PMID- 6918841 TI - Intracoronary streptokinase infusion. Nursing grand rounds. PMID- 6918843 TI - Deciphering diagnostic studies: arthroscopy. PMID- 6918842 TI - C.O.P.D. makes a bad first impression, but you'll find wonderful people underneath. PMID- 6918844 TI - Managing intraperitoneal chemotherapy: a new assault on ovarian cancer. PMID- 6918845 TI - Reducing the risk of infection from indwelling urethral catheters. PMID- 6918846 TI - How your state board works for you. PMID- 6918848 TI - A question of ethics: the patient's right to privacy. PMID- 6918847 TI - Your state nursing board may need your protection. PMID- 6918849 TI - Super opportunities outside the hospital--in independent practice. PMID- 6918850 TI - Setting priorities: how to stay efficient in hectic nursing situations. PMID- 6918851 TI - Nurses, let's support each other more. PMID- 6918853 TI - Four kinds of carelessness that can send you to court. PMID- 6918854 TI - Getting others to help you meet your goals. PMID- 6918852 TI - What to say (and not to say) when reporters ask questions. PMID- 6918855 TI - Take the guesswork out of going back to school. PMID- 6918856 TI - Court case: when the doctor doesn't come. PMID- 6918857 TI - Transcultural nursing: benefits for the nurse. PMID- 6918858 TI - A senior leadership experience within the YMCA and the community. PMID- 6918859 TI - Wanted: mentor relationships within nursing administration. PMID- 6918860 TI - A new approach to the development of a head nurse management course. PMID- 6918861 TI - The application of job satisfaction theory to the nursing profession. PMID- 6918862 TI - Leadership and stress. PMID- 6918866 TI - A nursing home near Dover in rural surroundings. Finance, budgeting and equipment. PMID- 6918864 TI - A career in private nursing. PMID- 6918863 TI - Consultation: an expectation of leadership. PMID- 6918865 TI - Communications. PMID- 6918867 TI - New careers advisory service: cardio-thoracic nursing - a visit to the National Heart and Chest Hospitals. PMID- 6918869 TI - Research. 3. The role of the nursing officer. PMID- 6918868 TI - The management of clinical specialities. 2. Accident and emergency unit. PMID- 6918870 TI - Accountability in nursing. PMID- 6918871 TI - Six paths for development. PMID- 6918872 TI - Facilitating research. PMID- 6918876 TI - Art and science of management: do we know what we're talking about? PMID- 6918875 TI - Group communication: when I speak no one listens. PMID- 6918874 TI - Interaction skills for nurse managers. PMID- 6918873 TI - Code blue evaluation. PMID- 6918877 TI - Supervisors get burned-out, too. PMID- 6918878 TI - Primary nursing demands change. PMID- 6918879 TI - Care plan: why should nursing care plans be made a permanent part of the medical record? PMID- 6918881 TI - Law for the nurse manager: nurse's responsibility for pre-employment/year by physicals. PMID- 6918882 TI - An American nurse's view of occupational health nursing in the U.S.S.R. PMID- 6918880 TI - Focus: on specialty pay--one nurse manager's opinion. PMID- 6918885 TI - The emergence of support groups from an employee health service department. PMID- 6918883 TI - It takes more than will power: the use of behavioral self-control in weight reduction. PMID- 6918884 TI - Basic components of a hospital employee health program. PMID- 6918886 TI - Cigarette smoking and the workplace: a deadly duo. PMID- 6918887 TI - Guidelines for assessing mental/psychosocial status. PMID- 6918888 TI - TB: an "extinct" disease that still cripples and kills. PMID- 6918889 TI - American Cancer Society to launch long-term study. PMID- 6918891 TI - [Role of the nursing service administrator - an analysis. II]. PMID- 6918890 TI - [Physical and psychological stress of nursing personnel]. PMID- 6918893 TI - [World Health Day 1982 - "fulfilled old age"]. PMID- 6918892 TI - [Man as measure of things--a modern fairy tale]. PMID- 6918895 TI - [Interview with Mr. Jozef Arnold, nurse administrator in the Zurich University Hospital (by Reinhilde Hufnagl)]. PMID- 6918896 TI - Everything you've been asking about continuing education. PMID- 6918894 TI - [Inservice continuing education in the Feldbach District Hospital - 1981]. PMID- 6918898 TI - What is high blood pressure and why is it important? PMID- 6918897 TI - A progressive calling - nursing requires lifelong learning. PMID- 6918901 TI - The management of night waking in older infants. PMID- 6918899 TI - PNPs, patients, parents, and sexuality. PMID- 6918900 TI - Marketing nurse practitioner services in a competitive land. PMID- 6918902 TI - Support groups for parents of chronically ill children. PMID- 6918903 TI - Cariogenic medications. PMID- 6918904 TI - Practice setting and the successful pediatric clinical specialist. PMID- 6918905 TI - Understanding tympanometry. PMID- 6918906 TI - A practical popular pacifier. PMID- 6918907 TI - Pediatric management problems: ventricular septal defect. PMID- 6918909 TI - Medicine and nursing practice - what it is and is not. PMID- 6918908 TI - Zinc dependency as a cause of chronic diarrhea in variant acrodermatitis enteropathica. AB - Two siblings with chronic diarrhea, growth failure, mood changes, and occasional cheilosis responded repeatedly to treatment with either pharmacologic doses of zinc or pancreatin (Viokase), and their symptoms were exacerbated after withdrawal of therapy. Pancreatic exocrine deficiency was ruled out in both cases. Proteolytic activity was 20% of normal in one infant tested. Plasma zinc concentration was normal. Plasma picolinic acid concentration was low in these two patients and in one previously reported patient (mean 3.6, normal 12.4 +/- 3.3 mumoles/liter). This is a characteristic shared with acrodermatitis enteropathica. The response to Viokase may be due to its content of picolinic acid and/or zinc or the correction of a deficiency of carboxypeptidase, a zinc requiring enzyme. PMID- 6918910 TI - Test services for schools of nursing 1981-82. NLN Test Service. PMID- 6918911 TI - Partners in educational preparation for nursing practice. PMID- 6918912 TI - Competencies and utilization of the baccalaureate graduate in nursing. PMID- 6918914 TI - The new nurse - a career for all reasons. PMID- 6918913 TI - Partners in educational preparation for nursing practice. PMID- 6918915 TI - The new nurse - a career to turn to and return to. PMID- 6918916 TI - The new nurse - a career for all reasons - and all people. PMID- 6918918 TI - The relationship of health beliefs, health locus of control, and self concept to the practice of breast self-examination in adult women. AB - This descriptive-correlational study was undertaken in order to determine if there were differences in the health beliefs, health locus of control, and self concept of adult women who practice breast self-examination (BSE) as compared to those women who do not. A sample of 207 women, drawn from a variety of settings, completed the four questionnaires, which were the research instruments. Data were analyzed using means, standard deviations, point biserial correlations, multiple regression, and Pearson product moment correlations. Analysis of the data revealed there were differences between the practicer and nonpracticer groups in terms of health beliefs, health locus of control, and self concept. Specifically, analysis revealed that being a practicer of BSE was correlated with higher levels of health beliefs and higher self-concept levels. practicers tended to be less inclined to have a health locus of control that depended upon a powerful other. PMID- 6918917 TI - Development of a health attitude scale. AB - A tool was developed to assess attitudes of patients with cardiac disease toward performing prescribed behaviors of their medical regimen. Two groups of subjects with heart disease were used to examine validity and reliability of the Miller Attitude Scale. One group included 480 members of Mended Hearts, Inc., and the second group consisted of 35 patients diagnosed with a first myocardial infarction. The second group repeated the attitude scale six months post hospitalization. Performance of the medical regimen by this group was verified at the six-month follow-up period. Using Spearman Rank Correlation, there was a significant relationship between attitudes and adherence behaviors for three of the five subscales. Alpha reliabilities revealed a high degree of internal consistency of scale items for all five subscales when testing both groups. A factor analysis resulted in eight factors accounting for the majority of the variance. Each of the five behaviors of the medical regimen clearly defined a factor supporting used of the Miller Attitude Scale for assessing attitudes of heart patients toward behaviors of their medical regimen. PMID- 6918919 TI - Psychological correlates of blood pressure: a closer examination of hostility, anxiety, and engagement. AB - Recent studies by other investigators have shown that hypertensives are more hostile and anxious than normotensives. The first part of this study examined the relationship between blood pressure measured daily over a one-week period and responses to a series of questions specifically developed to distinguish hypertensives from normotensives. Responses from this sample of undergraduates did not distinguish those with high blood pressure from those with normal values. Mean resting blood pressure was related to hostility and anxiety factor scores among males but not among females. Our second study used a sample of municipal employees and examined blood pressure as a function of comparable anxiety and hostility scores as well as a trait measure of overall "engagement-involvement." More highly engaged workers were no different in anxiety or hostility than less engaged workers. There was some evidence of more variable blood pressure for the former group. It is suggested that stable personality traits such as hostility and anxiety may both precede and follow the diagnosis of blood pressure. For nurses it is important to assess the patient's general psychological profile as well as his of her emotional state at the time of measurement. Repeated blood pressure readings are recommended especially for highly engaged individuals. PMID- 6918920 TI - The effect of oxygen inhalation on oral temperature. AB - A study was conducted to determine the effect of oxygen inhalation by nasal cannula on oral temperatures. One hundred healthy adult subjects were randomly assigned to a control and to three experimental groups that received 2, 4, and 6 liters per minute of oxygen for 30 minutes. Oral temperatures were measured before and 30 minutes after oxygen treatment. The data analysis did not show any significant effect of the treatment. This study encourages review of the common empirical practice of changing temperature sites from the preferred oral to the less acceptable rectal or axillary sites in patients receiving oxygen inhalation treatments. PMID- 6918921 TI - External pneumatic intermittent compression for treatment of dependent pregnancy edema. AB - A portable external pneumatic intermittent compression (EPIC) device has been successful in reducing peripheral edema. This study explored the effectiveness of EPIC for treating dependent pregnancy edema. In the study, 42 healthy pregnant women received EPIC for 30 minutes at 40 torr while in the left lateral recumbent position: Group One with mid-thigh boots, and Group Two with below-knee boots. Prior to compression, descriptive data were gathered, leg circumference measurements made, and surface skin temperatures recorded for three sites per leg. Vital signs were taken and pedal edema subjectively indexed. Following compression, circumferences, skin temperatures, vital signs, and edema indices were rerecorded. Three volumes were calculated for each leg using a mathematical model of leg segments as conical frustum units. Mean volume reductions for each leg were significant. The mid-thigh-length boots produced greater mean volume decreases. The volume decrease for calf, lower leg, and foot frustum units were significant. EPIC holds promise as a useful treatment for dependent pregnancy edema. PMID- 6918924 TI - Nursing philosophy and nursing research: in apposition or opposition? PMID- 6918923 TI - A Patient Satisfaction Instrument: precision by replication. AB - The Patient Satisfaction Instrument (PSI) was developed over a series of five clinical and administrative studies during a period of eight years, with a total of 600 patients, primarily medical-surgical inpatients and outpatients. The process illustrates measurement precision by replication. The PSI is a Likert type summated rating scale with three dimensions of patient satisfaction: technical-professional care, trust, patient education. It was adapted for use with inpatients from Risser's out-patient instrument. Internal consistency estimates appear satisfactory and stable across the various studies; for example, alpha coefficients for the Technical-Professional subscale average .79, Education coefficients average .78, and Trust coefficients average .88. Interitem, item subscale, and interscale correlations corroborate the alphas. Construct validity estimates were made via convergent/discriminant technique, discriminance, and predictive modeling. Empirical correlations moderately substantiated the multiple, convergent/discriminant predictions. Discriminance was strongly documented for all but the Education subscale, which had modest support. Predictive modeling produced moderate to strong validity estimates. Overall, the PSI has acceptable levels of validity and reliability with refinements indicated. PMID- 6918922 TI - Health problems encountered by nurse practitioners and physicians. AB - The effects of specialty, setting, and provider group on the distributions of health problems managed by nurse practitioners and physicians in obstetric gynecology, adult medicine, pediatrics, and family practice specialties are studied. Proportional samples by clinic were drawn from a total of 39,243 patient visits made to 16 ambulatory care clinics during an 18-week period. A Patient Encounter Form was used as the instrument and the ICD-9-CM was used as the coding system. Distributions of health problems differed between nurse practitioners and physicians in each clinic. Specialty affected the distributions of health problems managed by both provider groups. Setting affected the distributions of health problems for all specialties except the distributions of health problems not related to diseases or injuries (V codes) in family practice. Provider group effects were inconclusive. Community-based settings seem especially appropriate for nurse practitioner practice. PMID- 6918925 TI - The phenomenological approach in nursing research. PMID- 6918926 TI - The effect of medication distribution systems on medication errors. PMID- 6918927 TI - The Pink Sheet Syndrome. PMID- 6918928 TI - Self concept and health beliefs. PMID- 6918929 TI - Mental nursing. PMID- 6918931 TI - Mental nursing. 4. An alternative perspective. PMID- 6918930 TI - Mental nursing. 2. Implications of the new draft syllabus for mental nursing. PMID- 6918932 TI - Wound care. No. 7. Wound drainage. PMID- 6918933 TI - Mental nursing. 1. Devising and implementing new syllabuses for mental and mental handicap nurse training. PMID- 6918934 TI - Mental nursing: 3. A blue-print for mental handicap nurse training. PMID- 6918935 TI - Rehabilitation in Elton Ward, an interim regional secure unit. PMID- 6918937 TI - Catheter management. PMID- 6918938 TI - Help, dignity and independence for patients with catheters. PMID- 6918936 TI - New jobs for old. PMID- 6918939 TI - Catheters: alleviating urinary incontinence. PMID- 6918940 TI - The nurse-patient relationship-2. PMID- 6918941 TI - Psychiatric rehabilitation: a time for change. PMID- 6918942 TI - Death in the family. PMID- 6918944 TI - Communication with the patient in the intensive care unit. PMID- 6918943 TI - Spotlight on children: paediatrics present. 1. My viewpoint. PMID- 6918945 TI - Spotlight on children: paediatrics. 3. Children in hospital. PMID- 6918946 TI - Spotlight on children: paediatrics. 4. Help for Helen. PMID- 6918947 TI - Spotlight on children: paediatrics. 5. Shades of grey. PMID- 6918949 TI - Just for the record. PMID- 6918948 TI - The DNO with only half a district: district profile 1. PMID- 6918950 TI - 'When we talk about standards, we're considered a profession. When we talk about money, we're not.'. PMID- 6918951 TI - Nursing care study: an 11-year-old girl with spondylolisthesis. PMID- 6918953 TI - There's many a slip. PMID- 6918952 TI - Computers. 4. Implications of computerisation. PMID- 6918955 TI - The shoulder lift. PMID- 6918954 TI - Claiming benefits. 1. Attendance allowance. PMID- 6918956 TI - Continuity and communication--1. PMID- 6918957 TI - Second time around. PMID- 6918958 TI - Freedom at the Royal Free? PMID- 6918959 TI - A view across the Atlantic. PMID- 6918960 TI - Strictly in confidence. PMID- 6918961 TI - A question of time: out of the shadows. PMID- 6918962 TI - Hidradenitis suppurativa. PMID- 6918965 TI - A touch of skin--psoriasis. PMID- 6918964 TI - Working together. Staff at a psychogeriatric day unit found a closer working relationship with ambulancemen a valuable asset. PMID- 6918963 TI - Training in a time of change. PMID- 6918966 TI - Genital infection with herpes simplex virus. PMID- 6918967 TI - Systems of life No 88. Systems and signs: examining the cranial nerves - completed. PMID- 6918968 TI - Continuity and communication-2. PMID- 6918969 TI - Life begins at 60. Interview by Alison Dunn. PMID- 6918971 TI - Politics in the principality: district profile. 2. PMID- 6918970 TI - Facing up to the facts. PMID- 6918972 TI - Nursing care study: scoliosis. PMID- 6918973 TI - Claiming benefits. 3. Maternity needs. PMID- 6918974 TI - Epistaxis. PMID- 6918975 TI - Osteogenesis imperfecta. PMID- 6918976 TI - How to use a bedpan after spinal surgery. PMID- 6918977 TI - Curtains up! PMID- 6918978 TI - The games people play. PMID- 6918979 TI - Nursing care study: acquired methaemaglobinaemia. PMID- 6918980 TI - Home therapy for patients with haemophilia and Christmas disease. PMID- 6918981 TI - Claiming benefits. 4. Supplementary benefit and heating additions. PMID- 6918982 TI - Too much nit-picking? PMID- 6918983 TI - Audiometry. PMID- 6918985 TI - Rcn Congress 1982: too many sisters. PMID- 6918984 TI - Theories of learning and the teaching of nursing. PMID- 6918986 TI - Rcn Congress 1982: the Rcn's changing face. PMID- 6918987 TI - Rcn Congress 1982: a man with a mission. Interview by Jane Salvage. PMID- 6918988 TI - Wound care No. 8. Wound infection - cause and prevention. PMID- 6918989 TI - Rcn Congress 1982: when the college banned men. PMID- 6918990 TI - A borderline case. District profile 3. PMID- 6918991 TI - Nursing care study: hydronephrosis as a cause of intestinal obstruction. PMID- 6918992 TI - Claiming benefits. 5. Supplementary benefit and cash additions. PMID- 6918993 TI - A stitch in time - 2. A review of the literature. PMID- 6918996 TI - Planning patient care - 2. Ward organisation. PMID- 6918995 TI - Community nursing - prescription for excellence? PMID- 6918994 TI - How Surrey implemented the Court Report. PMID- 6918997 TI - A good idea, son! PMID- 6918998 TI - Fenney the fighter. Interview by Laurence Dopson. PMID- 6918999 TI - Evolution in Southampton: district profile 4. PMID- 6919000 TI - Renal replacement therapy. 1-2. Haemodialysis and complications. PMID- 6919001 TI - A stitch in time - 3. The research study. PMID- 6919002 TI - Nursing care study: two problems of infirmity. PMID- 6919003 TI - Claiming benefits. 6. Housing benefits. PMID- 6919004 TI - Contact lenses in aphakic infants. PMID- 6919005 TI - Systems of life No 89. Systems and signs: nervous system. Testing sensation. PMID- 6919006 TI - Health visiting: what will be its function in the future? PMID- 6919007 TI - A private education. PMID- 6919010 TI - Racism in nursing. PMID- 6919008 TI - School for thought. Interview by Laurence Dopson. PMID- 6919009 TI - The light at the end of the tunnel. PMID- 6919011 TI - Renal replacement therapy. 2--1. Access for haemodialysis. PMID- 6919012 TI - Renal replacement therapy. 2.2. Home dialysis. PMID- 6919015 TI - Symposium on maternal and newborn nursing. PMID- 6919014 TI - Impotence. PMID- 6919013 TI - An omental swing following radiation ulceration. PMID- 6919016 TI - The childbearing childrearing center. A nursing model. PMID- 6919017 TI - Symposium on women's health issues. PMID- 6919019 TI - Health behaviors of women. AB - This article has reviewed both historical and current perspectives on women's health and illness behaviors. It has considered the existing risks to optimal health as well as the potential changes which may occur as women's roles and lifestyles continue to change. Jenkins' model was used to provide a framework for examining the sequence of events which frequently comprise a health behavior, and interventions were offered for the various categories of need--information, motivation, and specific skills to enhance action. Health care providers need to be facilitators of positive health in women but must encourage the female client to determine her own goals and behaviors. The nursing role can include assessing health and illness behaviors, assisting the client with development of manageable health goals, offering specific intervention strategies, and providing ongoing monitoring and support as the woman moves toward her desired goal. As nurses become more knowledgeable about preventive care for women of today, especially in regard to their unique needs and behaviors, perhaps positive health action may be encouraged not only for the prevention of disease but also for the joy of being healthy. PMID- 6919020 TI - An approach to health assessment of women. PMID- 6919021 TI - Psychosocial stresses of working women. PMID- 6919024 TI - Aged women and health. PMID- 6919022 TI - The psychosocial impact of infertility. AB - I would like to conclude this article by making a special appeal to nurses and related health care professionals to appreciate the special needs of the infertile couple. In being denied a pregnancy and parenting experience when they truly desire it, they are faced with a life crisis of major proportions. It is the goal of the person who counsels infertile couples to help them resolve the crisis positively, and to develop new insights and strengths as a result. The infertile couple who so earnestly desire a family deserve respect and attention. They should be seen as having a legitimate health problem which has attendant emotional issues and overtones. Though they are rarely physically ill and do not usually find themselves incapable of performing their work and living functions, this neglected population suffers an enormous toll in the quality of their life. Health care professionals must be aware of the special feelings and issues of the infertile couple. PMID- 6919023 TI - The needs of women with gynecologic malignancies. PMID- 6919018 TI - Women's health: perspectives for nursing research. AB - The scope of women's health research is vast. Within the discipline of nursing, the scope of women's health research includes health variables studied within social and biophysical health contexts and as they are shaped by developmental stages. The unit of analysis in these studies is the woman, whether she is studied as an individual or as part of a population of women. Similar application of this framework, which is intended to chart the boundaries within which systematic study of women's health can occur, may suggest areas in which there is currently a deficit of empirical and theoretical work and may prompt nurse investigators to explore new questions. PMID- 6919025 TI - Comprehensive care during the postpartum period. PMID- 6919026 TI - A proposal: primary nursing for the mother-baby dyad. AB - Nurses who work in a maternity setting must define their role in terms of the families for whom they care. Care of the childbearing family includes the social, cultural, and economic environment in which the new baby and his family are a part. The postpartum period is an ideal time for the primary nurse fo influence the care of the baby and family in a way that supports their unique family system. The nurse who utilizes this opportunity to care for the family can contribute positively to the start of a new member of society. The interactional system of the infant and family can be viewed as a mutually dependent dyad that is best supported by consistent and knowledgeable nursing care. It is no longer reasonable to deny such care to maternity clients. Family-centered care has been shown to be successful in a variety of hospital maternity settings, improving care for the mother-baby dyad and promoting cost-effective staffing. The process of proposing such a change is challenging. Obstacles to change can be overcome and, although painful, they often lead to clearer definition of the proposal. Nursing must provide the impetus to sound family-centered care. The alternatives are no longer acceptable to consumers, and fragmented nursing care is seldom satisfying to nurses. There is much to be gained by fulfilling the true sense of family-centered postpartum care. PMID- 6919027 TI - Physiologic and psychosocial assessment in labor. AB - The details of physiological and psychosocial assessment are available in many texts, and the techniques are relatively simple. Several assumptions underlie an excellent labor assessment: 1. that the nurse has a thorough knowledge of the physiological processes of pregnancy and labor; 2. that the nurse has a thorough knowledge of the psychosocial implications of pregnancy and labor; 3. that the nurse has the ability to set priorities and balance the focus of her assessment; 4. that the nurse has the ability to refrain from stereotyping the woman in labor; 5. that the nurse does not let her own expectations of feelings and behavior in labor mask what the patient is really experiencing; and 6. that the nurse is willing to follow up, evaluate, and reassess in order to verify her assessments and improve her assessment skills. PMID- 6919028 TI - Hematologic disorders in pregnancy. PMID- 6919029 TI - Psychologic implications in high-risk pregnancy. PMID- 6919032 TI - Care of unconscious patients on ventilator. PMID- 6919031 TI - Curriculum change in nursing-V. Conceptual framework of community health orientation. PMID- 6919033 TI - Community forum 4 - preventive division: an apple a day. PMID- 6919030 TI - Nutrition across the woman's life cycle. Special emphasis on pregnancy. AB - Nutrition plays a crucial role in the maintenance of health of a woman throughout life, but assumes an even more important role during growth, pregnancy, lactation, and menopause. The nutrient reserves accumulated during other, nonstressful periods of life are of vital importance during these phases of physiological stress. Requirements for various nutrients, such as protein, carbohydrate, fat, minerals, and vitamins, throughout life are qualitatively similar; however, they change quantitatively with the rate and intensity of physiological processes taking place within the body. Pregnant and lactating women require more energy, protein, iron, calcium, and vitamins to meet their increased needs. Rapid growth during infancy, childhood, and adolescence also increases the requirements for essential nutrients. In the elderly female, it is important to decrease energy consumption as the basal metabolic rate declines. However, minerals and vitamins, particularly calcium, thiamine, and pyridoxine, continue to be as essential in the elderly population as in adult women. PMID- 6919036 TI - It's still a mystery. PMID- 6919034 TI - How did Helen die?. Interview by N Blackford. PMID- 6919037 TI - Reorganisation: after a lengthy battle... PMID- 6919038 TI - Issues in nursing. 4. A phoenix rises. PMID- 6919035 TI - Nature will provide. PMID- 6919039 TI - Issues in nursing. 4. Responsible and accountable. PMID- 6919040 TI - Are nurses apathetic? Catch'em while they're young. PMID- 6919041 TI - Centres of excellence. 4. Surrounded by toys and gold dust. PMID- 6919042 TI - Statistics for nurses. 2. More than coincidence. PMID- 6919043 TI - Students' forum: the skin. PMID- 6919044 TI - Catheter management: it's the size that's important. PMID- 6919045 TI - Incontinence: dignity at all times. PMID- 6919046 TI - Careers - stoma care: six of the best. PMID- 6919048 TI - Clinical forum 4. - Gynaecological nursing: it was worth it. PMID- 6919050 TI - Clinical forum 4. - Gynaecological nursing: social service. PMID- 6919049 TI - Clinical forum 4. - Gynaecological nursing: time and a word. PMID- 6919047 TI - Clinical forum 4. - Gynaecological nursing: of course! PMID- 6919051 TI - Clinical forum 4. - Gynecological nursing: sense and sensitivity. PMID- 6919052 TI - Better safe than sorry. PMID- 6919053 TI - Why nursing, to the letter? PMID- 6919054 TI - Issues in nursing: singing for their supper. Interview by M Allen. PMID- 6919055 TI - Statistics for nurses. 3. The truths behind the figures. PMID- 6919056 TI - Community nursing - Anytown anecedotes. 8. The millstone of milestones. PMID- 6919057 TI - Implications of reduced hours: shorter hours, more nurses. PMID- 6919058 TI - Violent patients: boiling point! PMID- 6919060 TI - Careers - ENT nursing: a nose for caring. PMID- 6919059 TI - Nursing care study - adenocarcinoma: out of the blue. PMID- 6919061 TI - Think before you have to fight. PMID- 6919062 TI - Open all hours? PMID- 6919063 TI - Student special: safe, obedient and quiet. PMID- 6919064 TI - Student special: are tutors past it? PMID- 6919066 TI - Student special: excuse my ignorance. PMID- 6919068 TI - Student special: green ones and blue ones. PMID- 6919069 TI - Issues in nursing. 2. To strike or not to strike? PMID- 6919067 TI - Student special: first impressions stick. PMID- 6919065 TI - Student special: a serious business. Interview by Catherine Sadler. PMID- 6919070 TI - Centres of excellence. 6. Around the corner. PMID- 6919071 TI - Management - reorganisation: no particular place to go. PMID- 6919072 TI - Genetics. PMID- 6919073 TI - Anesthetic nursing: extension and expansion. PMID- 6919075 TI - Careers - oncology nursing: one in four. PMID- 6919074 TI - Nursing care study - agoraphobia: Behind closed doors. PMID- 6919076 TI - Psychiatry/mental handicap forum. 4 - Nurse/psychologist relationship: all for one. PMID- 6919077 TI - Psychiatry/mental handicap forum. 4 - Nurse/psychologist relationship: breaking the barrier. PMID- 6919078 TI - Psychiatry/mental handicap forum. 4 - Music therapy: the sound of music. PMID- 6919079 TI - [Psychiatry/mental handicap forum. 4 - Teachers/nurses: go forward together]. PMID- 6919080 TI - Psychiatry/mental handicap forum. 4 - Teachers/nurses: society's wishes. PMID- 6919081 TI - The childbirth debate: taking an active role. PMID- 6919083 TI - Let's stick together. PMID- 6919082 TI - Profile - Helen Thompson: passport to adventure. Interview by Tamara Ross. PMID- 6919084 TI - Centres of excellence. 7. A cocktail of care. PMID- 6919085 TI - Issues in nursing. 3. Briggs for pudding. PMID- 6919086 TI - UKCC proposals: misgivings galore. PMID- 6919087 TI - Community nursing - Anytown anecdotes. 9. A breakthrough. PMID- 6919089 TI - Careers - care of the elderly; a state of mind. PMID- 6919088 TI - Nursing care study - total cystectomy: going home. PMID- 6919090 TI - Education forum. 3 - individual study: a step forward. PMID- 6919092 TI - Consensus management: balance of power. PMID- 6919091 TI - Education forum. 3 - individual study - the fullest possible use. PMID- 6919093 TI - Nurses' pay: chasing shadows. Nurses are worth more. PMID- 6919094 TI - A neuromuscular approach. 2. Get into condition. PMID- 6919096 TI - Centres of excellence. 8. It's a miracle! PMID- 6919095 TI - A tin a day. PMID- 6919097 TI - Postbasic nursing procedures. 3. Venepuncture. PMID- 6919098 TI - A confusing age-old problem. PMID- 6919099 TI - Acupuncture: a Chinese puzzle. PMID- 6919100 TI - Aids to sight: looking forward. PMID- 6919101 TI - Issues in nursing. 5. Cause and effect. PMID- 6919102 TI - Issues in mental handicap nursing. Crossroads and roundabouts. PMID- 6919103 TI - Genetics. 2. PMID- 6919104 TI - Careers - nursing spinal injuries: active commitment. PMID- 6919105 TI - Community forum. 5 - rehabilitation: a question of habit. PMID- 6919106 TI - Community forum. 5 - rehabilitation: start fighting. PMID- 6919107 TI - Accidents: the wasted years. PMID- 6919108 TI - Accidents: a call for help. PMID- 6919109 TI - Accidents: on an individual basis. PMID- 6919112 TI - Practice-based research: part of the equipment. PMID- 6919113 TI - Sight in babies: the pattern of research. PMID- 6919111 TI - A neuromuscular approach. 3. At ease. PMID- 6919110 TI - Accidents: where the nurse fits in. PMID- 6919114 TI - Pass on the education buck. PMID- 6919116 TI - Postbasic nursing procedures. 4. Intravenous drugs. PMID- 6919115 TI - Community nursing - Anytown anecdotes. 10. One for the road. PMID- 6919117 TI - Issues in nursing conference. 1. Side by side. PMID- 6919118 TI - Emergency obstetric units: flying squads. PMID- 6919119 TI - Nursing care study - asthma: plan of action. PMID- 6919120 TI - Careers - tropical diseases: a climate of care. PMID- 6919121 TI - Clinical forum. 5 - schizophrenia: chemical victims. PMID- 6919122 TI - Clinical forum. 5 - schizophrenia: the sooner the better. PMID- 6919123 TI - Clinical forum. 5 - schizophrenia: the body in question. PMID- 6919124 TI - Clinical forum. 5 - schizophrenia: ward talk. PMID- 6919125 TI - Clinical forum. 5 - schizophrenia: relatively speaking. PMID- 6919126 TI - Clinical forum. 5 - schizophrenia: trial run. PMID- 6919127 TI - Clinical forum. 5 - schizophrenia: the untouchables. PMID- 6919129 TI - A union committed to social change: National Union of Public Employees. PMID- 6919128 TI - Clinical forum. 5 - schizophrenia: never to be happy. PMID- 6919130 TI - Accident and emergency: the St Valentine's day disaster. PMID- 6919131 TI - Health education: setting a good example. PMID- 6919132 TI - Hearing aids: tracing the break. PMID- 6919133 TI - Western nursing in Somalia: and all before breakfast. PMID- 6919134 TI - A neuromuscular approach. 4. Handle with care. PMID- 6919136 TI - Issues in nursing conference. 2. High class dedication. PMID- 6919135 TI - Postbasic nursing procedures. 5. Intravenous drugs 2. PMID- 6919137 TI - One nurse's attack on micro-organisms. PMID- 6919138 TI - No more bricks. PMID- 6919139 TI - Cancer relief: the homely touch. PMID- 6919140 TI - Sleep patterns. PMID- 6919143 TI - Careers: infection control nursing: of microbes and men. PMID- 6919141 TI - Nursing care study: breaking free from pain. PMID- 6919142 TI - Nursing care study: another link in the chain. PMID- 6919144 TI - Psychiatry/mental handicap forum. 5. Primary nursing. PMID- 6919145 TI - Private confessions. PMID- 6919146 TI - Geriatric nursing: coping with confusional states. PMID- 6919147 TI - Nursing abroad: nursing pressure pays off. PMID- 6919148 TI - Marathon fever: beware the long distance runner. PMID- 6919149 TI - Spending: get your priorities right. PMID- 6919150 TI - Postbasic nursing procedures. 6. Intravenous drugs 3. PMID- 6919153 TI - A neuromuscular approach. 5. Easy on the base. PMID- 6919152 TI - A flip of the coin. PMID- 6919151 TI - House calls: the perils of being a district nurse in mufti. PMID- 6919154 TI - Future of nursing: a rare chance to break free. PMID- 6919155 TI - Anytown anecdotes: gone with the leaves. PMID- 6919156 TI - Cardiothoracic nursing: treating the hunger for air. PMID- 6919157 TI - Nursing care study: communication breakdown. PMID- 6919158 TI - Doctors may diagnose, and surgeons may operate... PMID- 6919159 TI - Careers: infectious diseases nursing. Expanding the germ of knowledge. PMID- 6919161 TI - [Health care education--education for people's health in Mozambique]. PMID- 6919160 TI - [Proposal for municipal college education]. PMID- 6919162 TI - [Literature search in health services research]. PMID- 6919163 TI - [Successful strategies in narcotics abuse]. PMID- 6919164 TI - [Report from continuing education for instructors in the pediatric sector]. PMID- 6919165 TI - [Story, an immigrant woman]. PMID- 6919166 TI - [Importance of contact visits during nursing instructors' undergraduate practical experience]. PMID- 6919167 TI - Ombudsman's corner. PMID- 6919168 TI - Emotional well-being of North Dakota nurses. PMID- 6919170 TI - Nurses, unions, and hospital attitudes. Case in point: Crestline Memorial Hosp. v. NLRB (668 F. 2d 243 - OHIO). PMID- 6919169 TI - Bedfalls and nursing liability: legal factors. PMID- 6919171 TI - Legal case briefs for nurses. N.C.: newborns: retrolental fibroplasia. MA: injection error; neuro damage. PMID- 6919173 TI - Malpractice insurance coverage for nurses. PMID- 6919172 TI - Gynecology: legal liability of nurse specialists. Case in point: Jones v. Harrisburg Polyclinic Hosp. et als (437 A. 2d 1134 - PA). PMID- 6919174 TI - Psychiatric patients: R.N. supervision and control. Case in point: the Bradley Center v. Wessner (287 S.E. 2d 716 - GA.). PMID- 6919175 TI - Legal case briefs for nurses. MD: Negligent patients: R.N. liability. N.Y.: Observing disturbed patients: liability. PMID- 6919176 TI - Abusive patients: nurses emotional reactions. Case in point: Hall v. Bio-Medical Application, Inc. (671- F. 2d 300 - ARK.). PMID- 6919177 TI - Pancreatic spasmolytic polypeptide (PSP): III. Pharmacology of a new porcine pancreatic polypeptide with spasmolytic and gastric acid secretion inhibitory effects. AB - Pancreatic spasmolytic Polypeptide (PSP) is a new porcine pancreatic polypeptide, which inhibits gastrointestinal motility and gastric acid secretion in laboratory animals after parenteral as well as oral administration. (1) PSP inhibits the amplitude of electrically stimulated contractions of the isolated guinea pig ileum. PSP's inhibitory effect is antagonized by phentolamine, but not by yohimbine. (2) PSP inhibits the motility of isolated guinea pig intestinal segments after intraluminal dosing. (3) PSP reduces intestinal motility in rabbits in vivo after intravenous and intraluminal administration, and in mice in vivo after subcutaneous injection. (4) PSP delays absorption of protein hydrolysate when it is administered orally in capsules to pigs and to pancreatectomized dogs. (5) PSP inhibits pentagastrin induced gastric acid secretion in rats after oral administration and in cats after subcutaneous and oral administration. The mechanism of action of PSP has so far not been finally elucidated. It seems likely that PSP interferes with endogenous acetylcholine release. Furthermore it might act by release of somatostatin from somatostatin cells in the gastrointestinal tract. It may have a direct or an indirect stimulant effect on alpha 2-receptors. PMID- 6919179 TI - [Liberated liberal nurses]. PMID- 6919178 TI - Therapy of experimental staphylococcal mastitis in the mouse with cloxacillin and rifampicin, alone and in combination. AB - Cloxacillin effectively killed Staphylococcus aureus in vitro and in experimental acute mastitis in the mouse, but was ineffective in reducing bacterial counts in those with experimental chronic mastitis. Rifampicin was similarly bactericidal for staphylococci in vitro and in acute mastitis but it also significantly reduced numbers of viable bacteria in chronic mastitis. Exposure of multiplying staphylococci in vitro and in vivo to rifampicin alone led to the emergence of resistant bacteria, but this was prevented by the use of a combination of rifampicin with cloxacillin. This combination showed neither antagonism nor synergy in vitro, was more effective than either antibiotic alone in acute mastitis and killed S aureus in the chronic infection as effectively as rifampicin alone. PMID- 6919183 TI - [Paramedical education in Auvergne]. PMID- 6919181 TI - [Small establishments, hidden shame]. PMID- 6919182 TI - [Mutuality in Auvergne]. PMID- 6919180 TI - [Moulin du Soleil: a center of rehabilitation through work]. PMID- 6919185 TI - [Carmes Street at Limoges]. PMID- 6919186 TI - [Vichy: a nursing service that exists]. PMID- 6919184 TI - [The University of Clermont-Ferrand, research center for nurses]. PMID- 6919187 TI - [The role of Hospital Service Agents in the health care team]. PMID- 6919188 TI - [Spinal fractures]. PMID- 6919190 TI - [Architecture and conception of care in England]. PMID- 6919189 TI - [Blood transfusion. 1. Whole blood transfusion]. PMID- 6919192 TI - [Bladder drainage in women]. PMID- 6919191 TI - [Cystitis]. PMID- 6919193 TI - [Crying spasm]. PMID- 6919194 TI - [The torture syndrome]. PMID- 6919196 TI - [All or part? Caring for a whole (an individual) and part of a whole (one of the hospital patients)]. PMID- 6919195 TI - [A heavy handicap: deafness]. PMID- 6919197 TI - [Belfort: an integrated health center at its beginning]. PMID- 6919198 TI - Opinion exchange: was it advocacy, insubordination...or both? PMID- 6919199 TI - 'Why not fit the job to the nurse'? PMID- 6919202 TI - How Uncle Sam whitewashed the nursing shortage. PMID- 6919200 TI - Prolonged regional analgesia with morphine--epidurally. PMID- 6919203 TI - Avoiding postop pitfalls with hip fracture patients. PMID- 6919201 TI - Before a runaway reaction...halt hypovolemic shock. PMID- 6919204 TI - What goes on in physical therapy. PMID- 6919205 TI - Large bowel diagnostics challenge your stress-reduction skills. PMID- 6919206 TI - Urinary tract obstruction: the hidden threats in treatment. PMID- 6919207 TI - The fine art of giving a physical. What assessing the mouth can tell you. PMID- 6919210 TI - Infection consult: common error can cause pneumonia. PMID- 6919208 TI - Legally speaking: in a crisis, you must count every minute. PMID- 6919209 TI - Nursing's cash value: how it's hidden; why it must be revealed. PMID- 6919211 TI - Your 'heat of the moment' guide to emergency drugs. PMID- 6919212 TI - Tattletale lesions: what nails can tell. PMID- 6919213 TI - Wanted: longer (and shorter) shifts...plus a little choice in the matter. PMID- 6919214 TI - Beware of the obvious with near-drowning victims. PMID- 6919215 TI - Hypothermia, in summer? PMID- 6919216 TI - Hooked: the story of one RN's battle with drugs. Interview by Ronni Sandroff. PMID- 6919217 TI - The fine art of giving a physical: exploring the neck and lymphatics. PMID- 6919218 TI - Potassium problems: which patient's in danger? PMID- 6919219 TI - 'Fair warnings' for patients facing esophagoscopy and gastroscopy. PMID- 6919220 TI - Legally speaking. Assisting at abortions: can you really say no? PMID- 6919221 TI - Spare the fools and interns. PMID- 6919222 TI - Forensic nursing: want to work in Oakalla Prison Hospital? PMID- 6919223 TI - Stop the "gifts" of infant milk formula. PMID- 6919224 TI - Quality Assurance Program: QAP know-how sparks zest. PMID- 6919225 TI - [Tobacco and pregnancy]. PMID- 6919226 TI - [Abdominal surgical emergencies during pregnancy]. PMID- 6919227 TI - [Vaccine and prevention of hepatitis B]. PMID- 6919228 TI - [Radiodiagnosis and pregnancy]. PMID- 6919229 TI - [Varied pathology, diagnosis sometimes challenging (pregnancy complications)]. PMID- 6919230 TI - [Medications and pregnancy]. PMID- 6919231 TI - [Mrs. A...'s icterus]. PMID- 6919232 TI - [Fever and pregnancy]. PMID- 6919233 TI - [Gram negative infections in obstetrics]. PMID- 6919234 TI - [Orthopedic problems in childhood and their treatment]. PMID- 6919237 TI - [Biologic value of maternal milk. From the International childhood Center]. PMID- 6919238 TI - [Breasts and breast feeding]. PMID- 6919235 TI - [Blindness in young children]. PMID- 6919236 TI - [Icterus and pregnancy]. PMID- 6919239 TI - [Body image in young girls]. PMID- 6919240 TI - [Breast and sexology]. PMID- 6919242 TI - [Breast feeding in a pediatric department]. PMID- 6919241 TI - [Maternal breast feeding]. PMID- 6919243 TI - [The "new" fathers or the eternal question" what does being a father mean?]. PMID- 6919244 TI - [Pregnancy and work]. PMID- 6919245 TI - [IIIrd International Congress on Menopause. From the International Health Foundation]. PMID- 6919246 TI - [Indocid]. PMID- 6919247 TI - [Pedagogy: the library. Apropos of the library...in nursing schools]. PMID- 6919248 TI - [The placebo: to please whom?]. PMID- 6919249 TI - [Complementary tests in acute phlebitis]. PMID- 6919250 TI - [Above all, try to prevent phlebitis]. PMID- 6919251 TI - [Medical treatment of phlebitis]. PMID- 6919252 TI - [Surgical treatment of phlebitis]. PMID- 6919253 TI - [Anatomo-physiologic basis of the venous system]. PMID- 6919255 TI - [Acute complications of phlebitis]. PMID- 6919254 TI - [Prevention of phlebitis]. PMID- 6919256 TI - [Sintrom]. PMID- 6919257 TI - [Functioning of a multidisciplinary pedo-psychiatric team]. PMID- 6919259 TI - [Paradental cysts]. PMID- 6919258 TI - [Clinical aspects of acute phlebitis of the extremities]. PMID- 6919260 TI - [Pathology of the oral mucosa and diagnosis of cancer]. PMID- 6919261 TI - [Oral oncology in 1982. Role of electrocoagulation]. PMID- 6919262 TI - [Multiple extractions]. PMID- 6919263 TI - [Stomatology: a varied field of activity]. PMID- 6919264 TI - [Fractures]. PMID- 6919265 TI - [Orthodontics]. PMID- 6919266 TI - [Loco-regional anesthesia in stomatology]. PMID- 6919267 TI - [General anesthesia in stomatology]. PMID- 6919268 TI - [Parodontology and hygiene]. PMID- 6919269 TI - [Biopsies in stomatology]. PMID- 6919271 TI - [Role of the operating room nurse]. PMID- 6919270 TI - [Fluoridated splints]. PMID- 6919272 TI - [Stomatology nursing]. PMID- 6919274 TI - [Medical secretaries and appointments]. PMID- 6919275 TI - [Recognizing and assessing nursing students, a student project]. PMID- 6919273 TI - [Dental auxiliaries]. PMID- 6919276 TI - [Diagnosis of cervical adenopathies]. PMID- 6919277 TI - [Glossodynia]. PMID- 6919278 TI - [Cardiovascular functional pathology]. PMID- 6919279 TI - [Pathology where the therapeutic relationship is primordial: functional pathology]. PMID- 6919280 TI - [Diagnostic tests for fatigue]. PMID- 6919281 TI - [Spasmophilia]. PMID- 6919283 TI - [Professional status of nursing staff: practice in the public sector]. PMID- 6919282 TI - [A clinical case of paroxysmal tachycardia]. PMID- 6919284 TI - [Functional pathology of the digestive system]. PMID- 6919286 TI - [Different ways of approaching a child]. PMID- 6919288 TI - [Children and school: difficulties]. PMID- 6919287 TI - [Children and their families, their difficulties in relating to one another]. PMID- 6919289 TI - [Psychological and psychiatric approaches to children: introduction]. PMID- 6919285 TI - [Children's games and drawings: means of expression and communication]. PMID- 6919290 TI - [Major therapeutic approaches in child psychiatry]. PMID- 6919291 TI - [Nurses in child and adolescent psychiatry]. PMID- 6919292 TI - [Physical death, social death]. PMID- 6919293 TI - [The first medical consultation in child psychiatry]. PMID- 6919294 TI - [Ankylostomiasis]. PMID- 6919295 TI - [Taeniasis]. PMID- 6919297 TI - [Need for better health education]. PMID- 6919296 TI - [Anguilluliasis]. PMID- 6919298 TI - [Trichinosis]. PMID- 6919299 TI - [Diagnostic and therapeutic synthesis of digestive nematode infections and cestode infections]. PMID- 6919300 TI - [A case of anguilluliasis aggravated by corticotherapy]. PMID- 6919301 TI - [Trichocephaliasis]. PMID- 6919302 TI - [Ascariasis]. PMID- 6919303 TI - [Oxyuriasis]. PMID- 6919304 TI - Intracranial metastatic tumors in Ibadan, Nigeria. PMID- 6919306 TI - From nursing service to nursing practice: the task of the 80s. PMID- 6919305 TI - Occupational mobility of Tar Heel nurses: a recent study. PMID- 6919307 TI - Serum studies of leucocyte elastase in acute and chronic lung diseases. AB - Immunoreactive leucocyte elastase was measured in the serum of patients with chronic obstructive bronchitis. No evidence was found to demonstrate the release of this enzyme in the pulmonary circulation. However the average serum concentrations (573 . 0 micrograms/l; SD +/- 261 . 0) were higher (2p less than 0 . 001) in this group of patients than in age matched control subjects (355 . 2 micrograms/l; SD +/- 274 . 8). Further studies confirmed this finding but patients with other active lung diseases had similarly increased leucocyte elastase concentration in the serum. This suggests that a raised serum leucocyte elastase concentration is a feature of active lung diseases and not a feature of obstructive bronchitis alone. PMID- 6919308 TI - [Looking at blindness]. PMID- 6919309 TI - [Psychodrama and sociodrama]. PMID- 6919310 TI - [General introduction of the graduate of the H.B.O.-V. (Higher Professional Education-Nursing) a problem?]. PMID- 6919311 TI - [Niehans' cell therapy? - Yes!]. PMID- 6919312 TI - [Observations on geriatrics]. PMID- 6919313 TI - [Experience with the portable insulin infusion pumps]. PMID- 6919315 TI - [A visit to the Indian Health Service in Phoenix - Arizona]. PMID- 6919314 TI - [Stew or caviar? A psychotherapeutic community]. PMID- 6919316 TI - Legal ledger: private malpractice insurance. PMID- 6919319 TI - The mentally retarded patient: a nursing challenge. PMID- 6919318 TI - Ethics, informed consent and the OR nurse. PMID- 6919317 TI - Interview with the Surgeon General Dr. C. Everett Koop. PMID- 6919321 TI - Writing for publication? an art and science or helpful hints for the budding author. PMID- 6919320 TI - [Biological activity of tRNA in rat liver during cycloheximide-blocked translation]. AB - The aminoacylation of tRNA was investigated with respect to protein synthesis in the rat liver. No correlation was found between the 85-90% inhibition of protein synthesis 2 h after cycloheximide injection and aminoacylation level of some tRNAs both in vivo and in vitro. A decrease in aminoacylation (28%) was established only for lysine. During the recovery phase of protein synthesis 12 and 24 h after cycloheximide treatment the aminoacylation maximal level of mixture with 14C amino acids, 14C leucine, 14C glutamic acid was unchanged. PMID- 6919322 TI - Balancing organizational demands with human needs: the ironic emphasis in schools of nursing. PMID- 6919323 TI - Health problems associated with dieting activities of a group of adolescent females. PMID- 6919325 TI - Childbirth belief and practice in a Garifuna (Black-Carib) village on the North Coast of Honduras. PMID- 6919324 TI - Barriers to health care: variations in interpretation of Appalachian client behavior by Appalachian and non-Appalachian health professionals. PMID- 6919326 TI - Examining ethnography for nurse researchers. PMID- 6919327 TI - The evolution of nursing research. PMID- 6919329 TI - Strategies for teaching nursing research: community assessment as a basis for nursing intervention. PMID- 6919328 TI - Ethical issues in nursing research. PMID- 6919330 TI - Using research in practice: a survey of research utilization in community health nursing. PMID- 6919331 TI - Researchmanship: research funding sources. PMID- 6919332 TI - Malpractice in nursing--Part I. PMID- 6919333 TI - The who, what, when, why and how of professional negotiations for nurses. PMID- 6919334 TI - Survey of maternity service in Ireland. PMID- 6919335 TI - Survey on maternity care services: post natal aspect of the study. PMID- 6919336 TI - Uniting nurses nationally and internationally. PMID- 6919337 TI - [The effect of heparin on the activation of kallikreinogen in human plasma]. PMID- 6919339 TI - Nurse practitioner students and graduates: demographics, 1974-80. PMID- 6919338 TI - Whither nurse practitioners - to wither? PMID- 6919340 TI - Nurse practitioner education in Virginia: Hampton Institute Nurse Practitioner Program. PMID- 6919341 TI - MCV/VCU nurse practitioner programs. PMID- 6919342 TI - Old Dominion University adult and family nurse clinician/practitioner program. PMID- 6919343 TI - UVA nurse practitioner programs: 1969-82. PMID- 6919344 TI - Spotlight on Virginia's nurse practitioners. PMID- 6919346 TI - Assessment and nursing intervention of tardive dyskinesia. PMID- 6919345 TI - Report from the People's Republic of China June 5 - June 25, 1981. PMID- 6919348 TI - [Budget activities: now we can justify the position we took. Interview by Kristina Lindgren]. PMID- 6919347 TI - [After a year of planning in the Laboratory Assistants' School in Stockholm: new education for laboratory assistants is now arranged]. PMID- 6919349 TI - [Enthusiasm as great in 1977 - have expectations been fulfilled? Marianne Lundqvist looks back on the 5 years. Interview by Jan Thomasson]. PMID- 6919350 TI - [Massive protest in the entire country: student nurses demand continued education to be still available]. PMID- 6919351 TI - [Great possibilities get good nurses through the current education]. PMID- 6919352 TI - [Massive protest in the entire country. Theoretic continued education is sufficient]. PMID- 6919354 TI - [Physician's boycott continuing]. PMID- 6919355 TI - [Government budget proposal 1982/83; summary. 1982 another lean year for wage earners]. PMID- 6919357 TI - [Stockholm: continued education put aside by 1983--county council has no advice]. PMID- 6919356 TI - [Karlstad: continued education realized in the Spring without physicians' cooperation]. PMID- 6919353 TI - [Government: continued education to stay till the year 1983]. PMID- 6919358 TI - [Preventive health care stressed and patients get a strong position]. PMID- 6919359 TI - [Study of roentgen proposed in Orebro: fewer substitute staff and more basic personnel]. PMID- 6919360 TI - [We must find a common basic viewpoint in our professional role before we as a professional body representative can bring concrete contents to the new education]. PMID- 6919361 TI - [Questions and answers about the new education]. PMID- 6919362 TI - [PSI (Public Services International)-congress: the only justification for the public sector. Interview by Jan Thomasson]. PMID- 6919364 TI - [SHSTF joins in the campaign for Poland]. PMID- 6919363 TI - [Roger Hellstrom visited PSI in London: international exchange important. Interview by Jan Thomasson]. PMID- 6919365 TI - [Polish pediatrician: we suffer shortages in everything. Interview by Lisbet Helleberg]. PMID- 6919366 TI - [Liability case: negligent check - wrong blood given]. PMID- 6919367 TI - [Liability cases: wrong solution given with catheterization]. PMID- 6919368 TI - [It is better that the county council has the responsibility for the Academic Hospital]. PMID- 6919369 TI - [Prenatal diagnosis. The prospective mother: I have understood it alright but it is poor information. Interview by Viveka Holmertz]. PMID- 6919370 TI - [Now we use only half for most dressings]. PMID- 6919371 TI - [Prenatal diagnosis. Midwife: the most it can prove--then the waiting for answers is the worst. Interview by Viveka Holmertz]. PMID- 6919372 TI - [USA: professional division keeps membership numbers low]. PMID- 6919375 TI - [Comprehensive campaign against poverty and disease: the entire society must take an active part in health care activities]. PMID- 6919376 TI - [Watch out doctor, here comes health care research!]. PMID- 6919377 TI - [Health services research: one doesn't need to be a professor to do research. Interview by Inger Lernevall]. PMID- 6919378 TI - [Continued education proceeds--despite physicians' boycott. Health care instructors give assistance to active nurses]. PMID- 6919373 TI - [Employers and professional organizations in agreement: clinical instructors assume physicians duties]. PMID- 6919379 TI - [Analysis inside SHSTF concludes: organization has no personal sovereignty in negotiations]. PMID- 6919374 TI - [I sent an applique to my district division--I thought we needed some encouragement. Interview by Viveka Holmertz]. PMID- 6919380 TI - [SHSTF's work environment responsibility for safety regulations for electrical materials: a step forward but our need is greater]. PMID- 6919381 TI - [Violence by patients is usually acute: now assault alarm can protect staff]. PMID- 6919383 TI - [Computerized records can soon become reality]. PMID- 6919382 TI - [Eva was threatened with a knive. Interview by Viveka Holmertz]. PMID- 6919384 TI - [Most important problems for Australian nurses: we must improve our entire education system]. PMID- 6919385 TI - [We've gone around in circles too long and only heard words]. PMID- 6919387 TI - [Indian health care in old Mexico]. PMID- 6919386 TI - [It is better to participate in DASIS than to have an undercover data processing. Interview by Inger Lernevall]. PMID- 6919388 TI - [High association between properdin factors BfF1 and HLA-B 18 in a Portuguese family (author's transl)]. AB - The HLA and the Bf systems were studied as part of a family investigation carried out in Portugal. In four generations the rare phenotype BfF1 could be determined four times and the BfF1S phenotype six times, HLA-B18 being simultaneously positive in all cases. Since the frequencies of the individual factors F1 and B18 do not differ essentially from those obtained in Central Europe and no inbreeding situation was present, the high-grade linkage disequilibrium between F1 and B18 may also be presumed for the Portuguese population. Neither among the F1/B18 homozygous nor among the heterozygous subjects could one discern any morbid state (e.g., insulin-dependent diabetes mellitus) from which an association with the F1/B18 haplotype could be deduced. Finally, the rarity of Bf factors, such as F1 and S0.7, is discussed from the standpoint of selection vs. mutation. PMID- 6919389 TI - The health services' connection: report from home care. PMID- 6919391 TI - Nurses' strikes - a personal view. PMID- 6919390 TI - Job satisfaction among Alberta nurse educators. Part two. PMID- 6919393 TI - Serial study of the complement fractions C3, C4 and C3PA in allergic children. AB - The C3, C4 and C3PA complement fractions were dosed by radial immunodiffusion in the serum of 25 children with ages from 4 to 9 years in a non symptomatic period comprehending 10 atopic asthmas (40,0% of the cases) 8 non atopic asthmas (32.0%) and 7 urticarias (28,0%). The quantitative dosage of the studied fractions was carried out in a serial form 7, 14, 30 and 45 days after the first determination, what made a total of 116 dosages of C3, 112 of C4 and 114 of C3PA. Globally, no differences were verified in the averages and standard deviations of the complement fractions studied in the various pathological situations considered. The complement anomaly more frequently observed was the C4 increase in 37,8% of the assays in patients with atopic asthma, 16,2% of the assays in patients with non-atopic asthma and in 33,3% of the assays in urticaria cases. The other complement fractions studied showed inconstant variations in some cases. The serial study demonstrated in the same patient, variations larger than 2 standard deviations in 25,8% of the assays for C3, 25,0% for C4 and 27,2% for C3PA, what may possibly indicate the great instability of the complement system which depends on a function, consumption or activation and synthesis relation, having to be taken into consideration in those assays comprehending the quantitative study of the seric complement fractions. PMID- 6919392 TI - The law and the lamp: the emergency doctrine. PMID- 6919394 TI - Severe Fletcher factor (plasma prekallikrein) deficiency with partial deficiency of Hageman factor (factor XII): report of a case with observation on in vivo and in vitro leukocyte chemotaxis. AB - A case of cross-reacting material-negative Fletcher trait with additional partial deficiency of Hageman factor (HF, Factor XII) is described. Although the patient presented with a recent history of frequent epistaxis, he had no other personal or family history of a tendency toward bleeding or infection. Similar to other cases of Fletcher trait, his plasma showed a markedly prolonged partial thromboplastin time which could be corrected by prolonged incubation with the surface-activator kaolin. Surface-induced fibrinolysis, amidolysis of alpha-N benzoyl-proline-L-phenylalanine-L-arginine-p-nitroanilide, and cold-promoted enhancement of factor VII activity, reactions requiring the presence in the plasma of fletcher factor (prekallikrein), in addition to Hageman factor and Fitzgerald factor (high-molecular weight kininogen), were also defective. In vivo chemotaxis of polymorphonuclear leukocytes and monocytes (Rebuck's skin window technique) in response to skin abrasions was defective, but was normal when diphtheria-tetanus toxoid was also applied. In vitro leukocyte chemotaxis (Boyden chamber technique) in response to normal or patient's own serum activated with zymosan was normal. Together with previous observations that kallikrein generated chemotactic activity, possibly via activation of C5, the present observations suggest that prekallikrein activation may be important for in vivo leukocyte chemotactic response to skin abrasion. The inheritance of Fletcher trait in this patient is unclear.l Although the father was an apparent heterozygote, the mother was completely normal for Fletcher factor procoagulant activity and antigen. The mild Hageman factor deficiency in the patient did not contribute significantly to the plasma defects described and was likely inherited from the father who had a low HF procoagulant activity. PMID- 6919397 TI - Nosocomial disease and the Kansas City, Missouri, Health Department. PMID- 6919396 TI - Definition and comparability of nosocomial infection rates. AB - Nosocomial infection rates are frequently calculated by dividing the number of infections acquired during a month by the number of patients discharged during that month. This method does not allow for prediction of future events or comparability between locations for statistical analysis. A more appropriate rate is the number of infections divided by patient-days spent in the hospital. This rate avoids the problems associated with the commonly used method. On the basis of the rate of infections per patient-day, it is possible to test for interhospital and intrahospital differences as well as for differences over time. PMID- 6919395 TI - Progressive resistance in a single strain of Acinetobacter calcoaceticus recovered during a nosocomial outbreak. AB - A study was undertaken to investigate a nosocomial outbreak of acinetobacter calcoaceticus. The outbreak occurred in a shock-trauma intensive care unit (ICU) during a 6-month period and involved a total of 37 cases. Although no deaths were attributable to Acinetobacter, 60% of patients from whom Acinetobacter was isolated were determined to have a lower respiratory tract infection. A significant difference (p less than 0.05) was noted between the length to stay in the unit of patients who acquired Acinetobacter (mean 23.9 days) and of those who remained free of the organism (mean 2.58 days). The average day on which cultures first became positive was 14.85. During the last 3 months of the outbreak, the ICU Acinetobacter isolates developed an unusual pattern of aminoglycoside resistance that differed significantly (p less than 0.001) from the sensitivities of non-ICU Acinetobacter isolates. No plasmids could be detected in selected aminoglycoside-resistance Acinetobacter. Pseudomonas aeruginosa isolated concurrently from patients with Acinetobacter showed no abnormal variation in antimicrobial sensitivities. These findings were interpreted to mean that the outbreak was the result of the persistence of a single strain of A. calcoaceticus within the ICU. Termination of the outbreak was attributed to initiation of control measures. PMID- 6919398 TI - Postoperative wound infections detected during hospitalization and after discharge in a community hospital. AB - Postoperative wound infections were evaluated in 1271 patients who had 1389 surgical procedures. There were 49 postoperative wound infections identified, of which 26 (53%) were discovered after discharge. Wound infections varied from 2.5% for clean wounds up to 13.3% for dirty wounds. Among the specialties, the infection rate ranged from no infection for otolaryngologists and urologists to 8.6% for general surgeons. With routine hospital surveillance, the overall infection rate was 1.8% or 2.2%, including readmissions for infection, but less than the actual rate of 3.8%. Persons who had three procedures had no infection rate of 27.3%; for two procedures, 8.1%; and for one procedure, 3.2%. Most postoperative wound infections detected after discharge were based on clinical grounds and not positive cultures. Rehospitalization was required for seven patients because of infection. This study demonstrates that postoperative wound infection surveillance must be continued after discharge. PMID- 6919399 TI - A system for filing hospital infection control literature. PMID- 6919400 TI - Programmed unit in clinical nursing practice. PMID- 6919401 TI - Hospital-wide surveillance: perspective for the practitioner. PMID- 6919404 TI - ANA presidency is 'rigorous, exhilarating,' says Nichols. PMID- 6919402 TI - Track record aids SNAs in union fight. PMID- 6919406 TI - ANF, city team up to promote health. PMID- 6919405 TI - Capital commentary. ANA testifies, submits statements on 7 proposals. PMID- 6919407 TI - Groups and ready to move on credentialing center. PMID- 6919403 TI - Nurses will lose benefits if hospitals drop Social Security. PMID- 6919408 TI - ANA offers three levels of action--choose one. PMID- 6919409 TI - Effects of coping skills training on nursing students' reaction to a stressful situation. PMID- 6919410 TI - Stressful situations and coping mechanisms of intensive care unit nurses at X Hospital. PMID- 6919411 TI - Temperature effect on the susceptibility of methicillin-resistant Staphylococcus aureus to four different cephalosporins. AB - Forty isolates of methicillin-resistant Staphylococcus aureus were tested for in vitro susceptibility to cephalothin, cefamandole, cefotaxime, and moxalactam, using the disk diffusion and microbroth dilution methods at incubation temperatures of 30 and 35 degrees C. Resistance to all four antibiotics was more clearly evident at an incubation temperature of 30 degrees C. PMID- 6919414 TI - [Functional assay of factor B. I. Purification of cobra venom factor and hemolytic assay of factor B (author's transl)]. PMID- 6919413 TI - Methicillin-resistant Staphylococcus aureus susceptibility testing with Abbott MS 2 system. AB - The antimicrobial susceptibilities of 100 methicillin=resistant Staphylococcus aureus strains were concurrently determined by the Abbott MS-2 System and by the standard disk diffusion method. Agreement between the two methods was 94% or greater for all of the antibiotics tested except for methicillin and gentamicin. This study indicates that the Abbott MS-2 cannot be relied upon for detection of methicillin resistance in clinical S. aureus isolates. PMID- 6919416 TI - Entitlement versus resources: an ethical dilemna. PMID- 6919412 TI - Comparative in vitro study of temocillin (BRL 17421), a new penicillin. AB - The activity of temocillin (BRL 17421), a new penicillin, was tested in vitro against 653 isolates of gram-negative bacilli and gram-positive cocci. The drug was compared with other beta-lactam antibiotics and tobramycin. It inhibited the majority of gram-negative bacilli tested except for Pseudomonas aeruginosa and Acinetobacter calcoaceticus, which were highly resistant. It was active against more than 50% of the multiresistant strains tested. Temocillin was more active than mezlocillin against most gram-negative bacilli and more active than moxalactam, ceftriaxone, and ceftazidime against Enterobacter spp. In general, it was slightly less active than the other drugs tested and had no activity against the gram-positive cocci. There was no significant change in drug activity when pH and medium were varied, and the effect of serum binding was minimal. There was no significant inoculum effect when the size of the inoculum was increased from 10(4) to 10(6) organisms per ml. PMID- 6919415 TI - Denmark Nursing Home: a model. PMID- 6919417 TI - Nursing: an emerging power in health. PMID- 6919418 TI - Future realities. PMID- 6919419 TI - Draft standards for nursing practice. PMID- 6919420 TI - What's all this about Key Members? PMID- 6919422 TI - Some perspectives on neonatal intensive care. PMID- 6919423 TI - Standards for care and their influence on nursing. PMID- 6919421 TI - The nurse and the law: get it on record! PMID- 6919424 TI - Humanization of the hospital. PMID- 6919427 TI - Are nurses afraid of mental retardation? PMID- 6919426 TI - A public hospital in Peshawar. PMID- 6919425 TI - Viral hepatitis and precautions to be taken by health personnel. PMID- 6919428 TI - Another professional dimension within the grasp of everyone: writing for the 'Journal'. PMID- 6919430 TI - Drug interactions with digoxin. PMID- 6919429 TI - The nurse and the law: judgement and counter-judgement. PMID- 6919431 TI - Anorexia nervosa--milieu therapy of young adolescents. PMID- 6919432 TI - The role and influence in policy making of nurses in the clinical setting. PMID- 6919434 TI - Educational strategies for nurses. PMID- 6919436 TI - Organizational climate: conformity and individual freedom. PMID- 6919435 TI - Coping of copping out--an alternative approach to addiction. PMID- 6919437 TI - Dependence--independence--interdependence. PMID- 6919438 TI - Factors predisposing to parturient paresis. PMID- 6919433 TI - Patient rights: power and dependency. PMID- 6919439 TI - The Rape Crisis Centre, South Australia. PMID- 6919441 TI - The antenatal teaching controversy. PMID- 6919440 TI - Man and disease - a brief look at one hundred and twenty years of opinion. PMID- 6919442 TI - Immediate feedback and test--scoring. PMID- 6919443 TI - Developing a teaching unit on vascular access of a hemodialysis client. PMID- 6919444 TI - A teaching guide for dialysis patients in their middle years. PMID- 6919445 TI - The application on Orem's theory in promoting self-care in a peritoneal dialysis facility. PMID- 6919446 TI - The successful training of a mentally retarded patient for CAPD. PMID- 6919447 TI - Speaking out! We have met the enemy and (s)he is us! PMID- 6919448 TI - Preceptorship is alive and well and working at BCIT. PMID- 6919450 TI - CNJ talks to... Susan Lee Painter, head, National Clearinghouse on Family Violence. Interview by Judith Banning. PMID- 6919449 TI - Wife abuse: an old family problem, a new health problem. PMID- 6919451 TI - The act of caring as expressed in a code of ethics. PMID- 6919453 TI - The CNA connection: the nursing unit administration program. PMID- 6919452 TI - Betwixt and between: juggling ethical responsibilities on today's nursing scene. PMID- 6919454 TI - Women's health education clinic. PMID- 6919455 TI - Restraining the elderly agitated patient: a hospital looks at its assessment and application policies. PMID- 6919458 TI - Burnout--a review of the literature with application to cancer nursing. PMID- 6919457 TI - Nursing management of patients receiving cancer chemotherapy. PMID- 6919456 TI - Use of drugs for pain with cancer patients. PMID- 6919459 TI - Cancer nursing and the law: the malpractice crisis--part 1. PMID- 6919460 TI - Programmed instruction: cancer care. Cancer prevention: carcinogenesis II. PMID- 6919462 TI - Research highlights: nursing research: an uncertain future. PMID- 6919461 TI - Pharmaceutics: clinical trials--a review of terms and principles: part I. PMID- 6919463 TI - Socialisation of the student nurse in the nursing profession. PMID- 6919464 TI - A survey of abandonment of student nurses at Greys Hospital. PMID- 6919465 TI - [Postgraduate nursing research in South African universities 1969-1979]. PMID- 6919466 TI - Osteitis - a case study. PMID- 6919467 TI - [Preparation for retirement and old age]. PMID- 6919468 TI - Reorganization of the South African Nursing Association and the implications thereof. PMID- 6919469 TI - The OSCE-experiment at MEDUNSA. PMID- 6919470 TI - [Evaluation of affect in clinical teaching]. PMID- 6919471 TI - [Professionalism of the nurse - the image of the profession towards the outside]. PMID- 6919472 TI - [Problems of student recruitment in nursing]. PMID- 6919474 TI - The mechanism of urinary kallikrein excretion in the rat. AB - 1. In male Wistar rats urinary kallikrein excretion was positively correlated with urinary flow and glomerular filtration rate (GFR). 2. Osmotic diuresis produced by a 30% (w/v) glucose solution increased urinary kallikrein, and a positive correlation between this variable and urine flow was observed. No correlation was observed with GFR. 3. The mechanism of urinary kallikrein excretion is interpreted as a wash-out effect of renal kallikrein. PMID- 6919473 TI - Complement-mediated inhibition of immune precipitation. II. Analysis by sucrose density gradient ultracentrifugation. AB - The factors influencing the ultracentrifugation characteristics of immune complexes generated in the presence of fresh normal human serum have been analysed. In the absence of alternative pathway factors B, D or Properdin, the size of complexes was increased. When classical pathway function was blocked, in C1q deficient serum or in the presence of Mg EGTA, although the proportion of complexes remaining in solution were reduced their size was similar to those formed in normal human serum. In C2 deficient serum, a heterogeneous population of complexes was generated. In all instances repletion with the appropriate missing complement component reversed the abnormality. We conclude that there is normally a rapid sequential process of classical followed by alternative pathway activation leading to stable soluble complexes. In the absence of C1 activation the alternative pathway process requires precipitation of the antigen-antibody aggregates whereas in normal serum these events occur in the fluid phase. We suggest that in C2 deficient serum the C1 and/or C4 reacted complexes fail to activate the alternative pathway efficiently. PMID- 6919475 TI - Mastectomy care study: adding years to life. PMID- 6919477 TI - Diabetic nutrition. PMID- 6919476 TI - Mastectomy care study: adding life to years. PMID- 6919478 TI - Hospital liaison: home - with care. PMID- 6919479 TI - Controversies in the treatment of exocrine pancreatic insufficiency. PMID- 6919480 TI - Advanced hemodynamic assessment. PMID- 6919481 TI - Sensory disturbances among children in the ICU. PMID- 6919483 TI - Emotional care in the ICU: St. Luke's Hospital, Milwaukee. PMID- 6919484 TI - Expanding critical care beds through a surgical observation subunit. PMID- 6919485 TI - Brain death. PMID- 6919482 TI - Cardiac auscultation. PMID- 6919491 TI - [Diagnostic studies of children with rheumatism and septic endocarditis]. PMID- 6919486 TI - Analysis and implementation of critical care programs: a marketing approach. PMID- 6919488 TI - [The kallikrein-kinin system and blood pressure regulation]. PMID- 6919492 TI - [Diagnosis and treatment of brain edema in infectious patients]. PMID- 6919490 TI - The induction of tRNAphe in mammalian lens cortex: a possible control point in the synthesis of alpha-crystallin. PMID- 6919487 TI - Viral exanthems. PMID- 6919489 TI - Activation and release of a trypsin-like proteinase from bovine lens alpha crystallin. PMID- 6919493 TI - [Symptoms of mental diseases]. PMID- 6919495 TI - [Organization of therapeutic and preventive care for industrial workers in the USSR]. PMID- 6919498 TI - [Emergency states in cardiology]. PMID- 6919497 TI - [Phenylketonuria]. PMID- 6919494 TI - [Left-handedness]. PMID- 6919496 TI - [Psoriasis (psora)]. PMID- 6919499 TI - [Computed tomography]. PMID- 6919501 TI - [Feeding of premature infants]. PMID- 6919500 TI - [Control of noise (material for discussions)]. PMID- 6919502 TI - [Quality indices of the prevention of respiratory tract, blood and skin infections]. PMID- 6919503 TI - [Botulism]. PMID- 6919504 TI - Gastric emptying and sieving of solid food and pancreatic and biliary secretion after solid meals in patients with truncal vagotomy and antrectomy. PMID- 6919507 TI - [Zinc in medicine]. PMID- 6919505 TI - Complement biosynthesis in human breast-milk macrophages and blood monocytes. AB - The availability of techniques for establishment of primary, long term monolayers of breast milk macrophages and blood monocytes permitted a direct comparison of biosynthetic functions of human tissue macrophage and its progenitor. In addition to previously described morphological differences, four specific characteristics of the breast milk macrophage were identified: (i) a reduced rate of total protein secretion relative to the monocyte; (ii) abrogation of the 3 day lag in complement secretion regularly observed in blood monocyte cultures; (iii) an increase in the secretion of complement proteins C2 and factor B; and (iv) an increase in the ratio of C2 : factor B secretion. These differences did not result from cell-cell interactions between monocytes and macrophages, stable factors elucidated by monocyte or macrophage monolayers, or heat-stable factors in breast milk. In addition, both monocytes and macrophages synthesized and secreted C3 in an apparently native but haemolytically inactive form. The differences observed suggest that macrophages may modulate local availability of complement proteins in tissues or in the early phase of an inflammatory response. PMID- 6919508 TI - [Aggressiveness of parents in a pediatric department: factors encouraging aggression]. PMID- 6919506 TI - Murine complement factor B (BF): sexual dimorphism and H-2-linked polymorphism. AB - Polymorphism of murine BF is described using agarose gel electrophoresis of EDTA plasma. The proteins were blotted onto cellulose nitrate sheets and BF was detected by incubation of these sheets with anti-BF serum, anti-IgG serum, and 125I-labeled protein A successively. After autoradiography, four or five main BF bands were found in plasma of male mice. The strain WLL/BrA (H-2bs) carried a more anodal variant than the strains 020/A(H-2pz), B10 (H-2b), B10.A (H-2a), B10.M (H-2f), and OIR (H-2q). In backcross and F2 generations the BF variants always cosegregated with the H-2 haplotypes. In this way linkage to H-2 could be established. When the electrophoretic BF patterns of males and females were compared, a sexual dimorphism was discovered; the females of each strain had only three main BF bands compared with the four or five found in males. However, no difference in level between males and females could be detected, probably because the three BF bands in the females were stronger. These data extend the information on the interspecies homology of the MHC and may open new possibilities for studies of the genetic organization and hormonal regulation of the H-2 complex. PMID- 6919509 TI - [Ergonomic approach to education: concept and reality of school ergonomics. 3]. PMID- 6919510 TI - [Magnesium]. PMID- 6919511 TI - [The ring on the finger of patients with upper extremity injuries]. PMID- 6919512 TI - [Hemostatics and hemostasis]. PMID- 6919513 TI - [From school health to health of the young]. PMID- 6919515 TI - [Occupational health nursing program]. PMID- 6919514 TI - [Chinese starch: or new framework for psychiatric care problems]. PMID- 6919517 TI - [The AIIC network: the administrative program of a health care unit]. PMID- 6919516 TI - [Legal aspects: accidents, improbabilities, what is predictable and what is not, what constitutes negligence in the administration of drugs?]. PMID- 6919520 TI - Interaction games and the patient. PMID- 6919518 TI - Science, the humanities, nursing research and nursing practice. PMID- 6919519 TI - The problem of the availability of drugs in hospital: the example of Makurdi, Nigeria. PMID- 6919521 TI - Nurse practitioners in primary health care: the Jamaican experience Part II. PMID- 6919522 TI - Concern - the mandate of the Christian nurse. PMID- 6919523 TI - Computers for critical care. PMID- 6919524 TI - A new adult tracheal button in the management of a near drowning victim. PMID- 6919525 TI - Hemodynamic monitoring in a coronary care unit. PMID- 6919526 TI - Intravenous techniques. PMID- 6919527 TI - Normal-pressure hydrocephalus: clinical symptoms, diagnosis, pathophysiology, and treatment. PMID- 6919528 TI - Subclavian steal: a review. AB - Subclavian steal syndrome is siphoning of blood from the baseovertebral circulation through a reversed flow in a vertebral artery caused by a proximal obstruction, most often an atherosclerotoic lesion, in the subclavian artery. Many patients are asymptomatic; many more probably have undiagnosed disease. Evidence of a possible steal can be detected by unequal upper-extremity pressures and decreased unilateral arm pulse. When symptoms do exist, they may be cerebral, cerebral and brachial, or brachial only. Treatment of choice is a symptomatic patient with confirmed diagnosis by angiography is surgical revascularization. Patient education plays a significant role in reduction of risk factors associated with atherosclerosis and recognition of progression of the disease. Complete vascular workup is warranted from any patient with atherosclerosis. PMID- 6919531 TI - Chronic accelerated idioventricular rhythm. PMID- 6919529 TI - Health beliefs of and adherence to the medical regimen by patients with ischemic heart disease. PMID- 6919530 TI - Trepopnea resulting from large aneurysm of sinus of Valsalva and descending aorta. PMID- 6919532 TI - Recurrent severe reaction to iodinated contrast media during cardiac catheterization. PMID- 6919533 TI - Nursing considerations of the burned patient during the emergent period. PMID- 6919534 TI - Nursing aspects of the surgical treatment of idiopathic hypertrophic subaortic stenosis. AB - Preoperative and postoperative nursing assessments and interventions of patients with IHSS are similar in principle to those for other adult patients undergoing cardiac surgery. The potential complications following left ventriculomyotomy myectomy are identified in Table III. The complications are paralleled with major nursing interventions. In summary, IHSS patients specifically are at greater risk of preoperative sudden death and postoperative dysrhythmias which warrants discriminating nursing observation. PMID- 6919536 TI - A study in intracardiac conduction with special reference to the Ashman phenomenon. PMID- 6919535 TI - Giant cell arteritis-variation on a theme. PMID- 6919537 TI - Lactate dehydrogenase isoenzymes expressed as a percentage of the total activity. PMID- 6919538 TI - Accuracy of protein biosynthesis. A kinetic study of the reaction of poly(U) programmed ribosomes with a leucyl-tRNA2-elongation factor Tu-GTP complex. AB - We have determined several kinetic parameters for the reaction of poly(U) programmed ribosomes with the near-cognate ternary complex of leucyl-tRNA2, elongation factor Tu (EF-Tu), and GTP. From single-turnover experiments at 5 degrees C with the ribosomes present in excess we find that the apparent second order rate constant for GTP hydrolysis is 0.4 X 10(6) M-1 s-1, that the cleavage step is faster than 4 s-1 and that the apparent rate constant for peptide formation is 6 +/- 3 s-1. From multiple-turnover experiments at 5 degrees C, with the ternary complex present in excess we find that kcat for GTP hydrolysis is 0.4 s-1 and Km is 1.6 microM. For both kinds of experiment the ratio of peptide formed to GTP hydrolyzed is 0.05 +/- 0.2. Comparison of these results with those obtained with the cognate complex show that the ribosome distinguishes between the cognate and near-cognate complexes, not on the basis of the forward rate constants, but on the basis of the reverse and rejection rate constants, which differ for the two complexes by at least 4000- and 100-fold, respectively. Both in ternary complex selection and in proofreading, the frequency of errors observed is much higher than might be expected from these large differences in rate constant. The reason is that, even for the near-cognate species, the rates of ternary complex rejection and aminoacyl-tRNA rejection are not overwhelmingly greater than the forward rate constants for GTP hydrolysis and peptidyl-tRNA formation, respectively. The outcome of these reactions is, therefore, at least partially under kinetic rather than thermodynamic control, leading to the trapping of errors which would not be made in a slow process. PMID- 6919539 TI - Structure of the omega-aminocarboxylic acid-binding sites of human plasminogen. Arginine 70 and aspartic acid 56 are essential for binding of ligand by kringle 4. PMID- 6919540 TI - Vanadate-induced movements of Ca2+ and K+ in human red blood cells. AB - Fresh human red blood cells become highly labeled with 45Ca2+ when exposed to 0.5 mM vanadate. The effect of vanadate requires its penetration into the cell, and is attributed to the inhibition of the outwardly directed Ca2+-pumping ATPase which would otherwise "mask" the uptake of 45Ca2+. Since the inhibition of the CA2+ pump by vanadate is not complete, a transmembrane Ca2+-Ca2+ exchange can be detected. The influx leg of the exchange is inhibited by verapamil, quinidine, and Co2+. This, as well as additional (kinetic) evidence, indicates that the influx of Ca2+ is a carrier-mediated process. Experiments in which the transmembrane K+ gradient has been abolished or decreased with ionophores, or by increasing the K+ concentration in the medium, suggest that the K+ gradient may play a role in the influx of Ca2+. The vanadate-induced accumulation of Ca2+ by red cells promotes a massive efflux of K+, indicating the activation of a Ca2+ sensitive K+-channel. The results indicate the occurrence of a slow cycling of Ca2+ across the red cell membrane. The influx leg of the cycle occurs through a verapamil-sensitive channel, and is possibly driven by the discharge of the transmembrane K+ gradient. The efflux leg of the cycle consists of the Ca2+ pumping ATPase. PMID- 6919541 TI - Transcription and precursor processing of normal and mutant human tRNAiMet genes in a homologous cell-free system. AB - Two human tRNAiMet genes were previously cloned from a recombinant library of fetal liver DNA (Santos, T., and Zasloff, M. (1981) Cell 23, 699-709). One gene differed from the common vertebrate sequence by a G to T transversion at position 56, occupied exclusively by a purine in all prokaryotic and eukaryotic tRNAs. In this study, we show that although both tRNAiMet genes are transcribed in an in vitro system from KB cells, normal post-transcriptional processing of the mutant gene transcript is interrupted. While the primary transcript of the normal gene undergoes stepwise excision of its 5' and 3' terminal sequences, 5' preceding 3', only the 5' leader of the primary transcript of the mutant gene is excised, resulting in the accumulation of an intermediate containing an unprocessed 3' trailer. The results suggest that certain eukaryotic tRNA mutations may not appear in mature tRNA species due to the effects of the mutation on precursor processing. PMID- 6919543 TI - The cobra venom factor-dependent C3 convertase of human complement. A kinetic and thermodynamic analysis of a protease acting on its natural high molecular weight substrate. PMID- 6919542 TI - Factors from wheat germ that enhance the activity of eukaryotic initiation factor eIF-2. Isolation and characterization of Co-eIF-2 beta. AB - A factor has been isolated from wheat germ that enhances the ability of initiation factor 2 (eIF-2) to form a ternary complex with GTP and Met-tRNAf and enhances the binding of Met-tRNAf to 40 s ribosomal subunits. This factor, designated Co-eIF2 beta, is a monomeric protein with a molecular weight of approximately 83,000. Wheat germ eIF-2 forms a stable binary complex with GDP but not with GTP. Co-eIF-2 beta enhances the formation of an eIF-2 . GDP complex, but does not enable eIF-2 to form a stable complex with GTP. PMID- 6919544 TI - Long-term sexual concerns in the client with ileostomy. PMID- 6919545 TI - Professional burnout part two: a survey of enterostomal therapists. PMID- 6919546 TI - Surgery for the child ostomate. PMID- 6919547 TI - Management of a permanent indwelling empyema tube. PMID- 6919548 TI - Thoughts of an old practitioner. PMID- 6919550 TI - Frontiers of nursing in the twenty-first century: development of models and theories on the concept of nursing. AB - Theories and models on the concept of nursing are reviewed briefly and their contribution then assessed in terms of their potential to advance the scientific basis of nursing practice. The constructs are acknowledged to have moved the focus of nursing from disease to patient need and provided different ways of looking at the nurse's contribution. Yet, despite this advance, the constructs have not been put to the rigours of scientific testing and so remain at the level of speculation. Therefore, towards the developments for the twenty-first century it is proposed that these ideas should be put to the test to establish their relevance in the real world of nursing care. This requires: a framework from which the nature, extent and purpose of care can be specified; independent criteria which can be used to judge effectiveness of care; knowledge as it relates to the different and varied core concepts underlying the practice of nursing; and a working definition of need. In addition, the extent of care for the community needs to be made explicit through research. Together, this represents a challenge to develop theories which are logically related to single core concepts which themselves represent specific areas of actual nursing practice. PMID- 6919549 TI - The nursing process--is the title right? AB - The use of the term nursing process is traced from the 1950s. The author argues that the nursing process is now used as a substitute for nursing. In this paper questions are raised as to whether problem-solving is all there is to nursing and whether problem solving is peculiar to nursing. It is further argued that whilst the nursing process recognizes the purpose of the problem-solving aspects of the nurse's work, it ignores the subjective or intuitive aspects of nursing. It also ignores the role of experience, logic and expert opinion as bases for nursing practice, the author contends. She concludes that because the nursing process stresses a dominant and independent function for the nurse this may undermine the value of collaboration of health professionals and the development of the client's self reliance. PMID- 6919551 TI - Models of nursing as the basis for curriculum development: some rationales and implications. AB - Within this paper the notion of a model of nursing as a basis for curriculum development is explored. Firstly the factors which a curriculum developer in nursing might take under initial consideration are discussed. It is then argued that a nursing faculty must identify and define its conceptualization of nursing and what it is to be a nurse. The process of conceptualizing nursing itself is examined. The paper goes onto argue that once a nursing faculty has reached a consensus view as to what constitutes nursing, then it either designs or selects a model of nursing which supports their particular conceptualization. Educational literature is cited to support the view that curriculum design, process and content are interrelated and that student learning is facilitated when the relationship between these three factors is coordinated. It is suggested that a nursing curriculum can achieve such an integration if a model of nursing is used as the conceptual framework. Finally some of the implications of adopting a model of nursing are stated. PMID- 6919552 TI - Development of models and theories on the concept of nursing. AB - This paper shows how models can be used by practitioners of nursing as a practical tool to analyse their own practice, in particular to assess needs and to plan, implement, and evaluate care. It is argued that the impact of existing work in theory development has been relatively small, at least in the UK, because the theories are not sufficiently specific to everyday nursing activities and the models are over elaborate and not universally applicable. A simple model of nursing, based on a systems approach is presented and applied to one particular field of nursing practice, i.e. health visiting. The model, which can be used in any field of nursing, stresses the reciprocity of the nurse-patient relationship, and the significance of the environment in determining the concepts of nurse, patient and nursing. PMID- 6919554 TI - Psychotherapy by nurses--some special characteristics. AB - On an inpatient drug dependency unit, the nursing role was recently extended to include structured individual interviews. Each new patient was allocated to a particular nurse. The success of the scheme is discussed and some of the difficulties encountered are described. A new framework, the Friend role and the Therapist role, is outlined and some benefits of the use of this framework are detailed. PMID- 6919553 TI - Quality assurance programme for nursing. AB - This article describes a conceptual and methodological framework for evaluating nursing care quality. The conceptual framework is based on Orem's theory of self care which emphasizes the importance of decisions in the selection of nursing process based on patient status and problems. The primary outcome criteria is self-care. The methodological framework is based on Greenfield's criteria maps methodology for linking patient status (problems or diagnoses) to decisions about nursing interventions and linking these specific nursing intervention criteria to desired outcomes for self-care. The article further describes a multiagency quality assurance programme for nursing. The programme includes: a definition of criteria and standards across agencies; nursing care management protocols that define standards of care; continuing education courses for nursing based on management protocols; the maps method of auditing actual and recorded nursing process and patient outcomes as defined in the management protocol. PMID- 6919555 TI - The Yorkshire Ripper case: not only was Peter Sutcliffe on trial! PMID- 6919556 TI - Gerontology: older women. PMID- 6919557 TI - Sleep loss in the aged: implications for nursing practice. PMID- 6919558 TI - Sleep patterns of hospitalized and nonhospitalized aged individuals. PMID- 6919560 TI - Old, alone, and in need. PMID- 6919559 TI - Insomnia: causes and treatment, particularly in the elderly. PMID- 6919561 TI - Assisting the older woman with cosmetics. PMID- 6919562 TI - Adjustment of older persons in nursing homes. PMID- 6919563 TI - For nursing homes: a linkage system to mental health centers. PMID- 6919564 TI - Nursing innovation for dry skin care of the feet in the elderly: a demonstration project. PMID- 6919565 TI - Reality orientation therapy for the institutionalized elderly. PMID- 6919566 TI - Aging and memory loss. PMID- 6919568 TI - Effects of restriction of sodium or administration of fludrocortisone on parotid salivary kallikrein in man. AB - Urinary kallikrein is increased by restriction of dietary sodium and by administration of fludrocortisone, a sodium-retaining steroid. In order to determine whether salivary kallikrein responds similarly, we studied 16 normal volunteers after 1-week periods of daily intake of 9, 109, and 259 mEQ of sodium; 10 subjects were studied after addition of 0.6 mg/day fludrocortisone for a week to a regimen of 109 mEq/day sodium. During sodium restriction, parotid saliva had a significantly higher mean concentration of kallikrein ad potassium and a significantly lower concentration of sodium than during periods of intake of 109 or 259 mEq/day sodium. Sodium restriction also caused significantly higher urinary excretion of kallikrein and aldosterone. Salivary amylase remained unchanged during the three sodium periods. Administration of fludrocortisone significantly increased the mean concentration of parotid kallikrein and excretion of urinary kallikrein in comparison with control levels, however the concentrations of parotid sodium and potassium did not change significantly. Four patients studied before and after removal of aldosterone-producing adenomas each showed decreased concentrations of parotid kallikrein and potassium and increased concentrations of parotid sodium after surgery. It is concluded that both salivary and urinary kallikrein increased in response to restriction of sodium and that these increases were mediated by levels of sodium-retaining steroid. Increased output of kallikrein in response to increased levels of sodium retaining steroid may be a generalized response of organs that contain glandular kallikrein and can conserve sodium. PMID- 6919567 TI - Biosynthesis of C4 by mouse peritoneal macrophages. I. Characterization of an in vitro culture system and comparison of C4 synthesis by "low" vs "high" C4 strains. AB - C4 biosynthesis and secretion in mouse resident peritoneal macrophage cultures was examined by functional and antigenic analysis. The rate of secretion of functional and antigenic C4 decreased in parallel in short-term culture despite constant total protein secretion and increasing factor B secretion. Feedback inhibition and protease degradation did not account for the decreasing rate of C4 secretion. Despite a 10-fold difference in plasma C4 levels between high C4 (H-2d haplotype) and low C4 (H-2k haplotype) mouse strains, resident peritoneal macrophages from both strains synthesized and secreted similar amounts of antigenic and functional C4 in short-term culture. The C4 secreted by H-2d and H 2k macrophages was relatively stable, because it exhibited only approximately 2% loss of hemolytic activity per hour in culture. These data suggest that an unidentified environmental signal leads to the specific decrease in C4 synthesis and secretion by peritoneal macrophages and that a regulatory defect may not be present, at least in macrophages, to account for the low C4 levels in the H-2k haplotype. PMID- 6919569 TI - Blood kinins, their concentration in normal subjects and in patients with congenital deficiency in plasma prekallikrein and kininogen. AB - Kinins are potent vasodilator peptides that may participate in the regulation of local blood flow and blood pressure. Here we report a new method to measure kinins in blood. For this, 6 ml of blood are collected in less than 10 sec directly into 25 ml of ethanol. Kinins are further purified by extracting lipids with ether and by removing kininogen and other interfering substances by chromatography on QAE Sephadex and BioRex 70; then they are measured by a sensitive RIA. In 22 normal subjects, after correction for recovery (50%), the kinin concentration in peripheral venous blood was 25.2 +/- 2.6 pg/ml (mean +/- S.E.M.). To determine whether the circulating kinins are formed by plasma kallikrein or other kininogenases, the concentration of blood kinins was measured in the venous blood of three patients with congenital deficiency in plasma prekallikrein (Fletcher trait) and in one patient with congenital deficiency in the substrate of plasma kallikrein, high-molecular-weight kininogen (Fitzgerald trait). In the three subjects with Fletcher trait, blood kinins were 16, 21, and 31 pg/ml, whereas in the subject with Fitzgerald trait they were 26 pg/ml. Normal subjects had concentrations in the same range (9 to 55 pg/ml), indicating that the concentration of blood kinins in normal subjects is much lower than previously reported (70 to 5000 pg/ml). These results also suggest that kininogenases other than plasma kallikrein may generate circulating kinins. PMID- 6919570 TI - Therapy of methicillin-resistant Staphylococcus epidermidis experimental endocarditis. AB - Antibiotic therapy of methicillin-resistant Staphylococcus epidermidis endocarditis was investigated with the rabbit endocarditis model. Time-kill studies in vitro demonstrated that gentamicin and rifampin had the most rapid early bactericidal rates. With rifampin alone, rifampin-resistant subpopulations emerged. Combinations of antibiotics with gentamicin or rifampin in vitro did not significantly alter the killing rate but prevented emergence of subpopulations resistant to the latter. In the rabbit endocarditis model, gentamicin and vancomycin were the most effective single antibiotic regimens in terms of ability to reduce the bacterial densities on cardiac valve vegetations. Five treatment regimens were equally effective, including vancomycin, gentamicin, vancomycin plus rifampin or gentamicin, and rifampin plus gentamicin. The three-drug combination of vancomycin, rifampin, and gentamicin did not significantly improve the results. Cephalothin therapy was significantly less effective than any of the regimens noted above. It was no more effective than no treatment at 2 days and was only slightly more effective at 4 days. This result with cephalothin treatment was not predicted by routine types of in vitro antibiotic susceptibility testing. Treatment of rabbits with methicillin or cephalothin was associated with an increase in the subpopulation of bacteria resistant to the respective drugs. A number of regimens show potential for therapy of these infections, including vancomycin plus rifampin or gentamicin, rifampin plus gentamicin, and vancomycin alone. PMID- 6919571 TI - Providing preceptors for nursing students: what questions should you ask? PMID- 6919572 TI - Variable billing for services: new fiscal direction for nursing. AB - The advantages of variable billing for nursing care that: It identifies revenue nursing cost centers. It facilitates systematic control of revenue and expenses, improving budget planning and management. It generates a tremendous amount of data that can be used in administrative planning and decision making. It is more equitable than past billing practices for the patient, the third-party payer, and the hospital, making it a public relations asset. The disadvantages of variable billing are that: Charges at one hospital are not easily compared with those at another. The mix of patients at varying classification levels has a significant effect on revenue, thus increasing the possibility of lower revenue. More accountability and in some cases more work is required of nursing administrators. In this article, the practical application of variable billing in acute care settings has been discussed. It is hoped that the information provided here will stimulate nursing administrators to assess the feasibility of implementing varible billing for nursing services as a fiscal practice in their own institutions. PMID- 6919573 TI - Skilled clinical knowledge: the value of perceptual awareness, Part 2. PMID- 6919574 TI - Decentralized budgeting: holding the purse strings, Part 2. PMID- 6919575 TI - Theory into hospital practice: a pilot implementation. AB - Implementing the Adaptation Model required that the model's concepts be explicitly identified, defined, and understood. Guidelines, standards and tools had to be revised or developed. Effective nursing administration leadership and the personal and professional commitment of administrators, educators, and staff nurses to the goal were necessary ingredients. The abstract nature of theory often requires sheer determination and hard thinking if it is to be effectively applied to practice. A formal education process must also be dynamic and ongoing. Project members continue to gain greater insight into the model's structure, identify problems in its application, and seek ways to solve them. Their combined, concentrated efforts have proved a cost-effective way to close gap between education and practice. The project's initial outcomes, increased patient satisfaction and expanded professional nursing, support the application of the Adaptation Model in our hospital. Further validation of its structure and the value of its outcomes, however, needs additional study, and extended application in multiple practice settings. Validation of the Roy Adaptation Model or any of the evolving conceptual frameworks for nursing practice requires use, input, and evaluation by nurses in all settings. Opening the theoretical domain to hospital nurses needs the support and leadership of nursing and hospital administrators. PMID- 6919576 TI - Political midwifery. PMID- 6919577 TI - Nurse-midwifery practice in an in-hospital birthing center: 2050 births. PMID- 6919578 TI - The ACNM and the NCHCA--the significance of membership. PMID- 6919579 TI - Management of postpartum breast engorgement in nonbreastfeeding women by mechanical extraction of milk. PMID- 6919580 TI - A successful pilot off-campus nurse-midwifery program. PMID- 6919583 TI - Inotropic effects of vanadate in isolated rat and guinea-pig heart under conditions which modify calcium pools involved in contractile activation. PMID- 6919581 TI - Observations of early mother--infant interaction in Liberia. PMID- 6919582 TI - Urinary kallikrein excretion in grade school children with high and low blood pressure. PMID- 6919584 TI - Helping families cope with sudden infant death syndrome. PMID- 6919585 TI - Nursing support of the cancer patient. PMID- 6919586 TI - Helping the terminal patient's family. PMID- 6919588 TI - Dealing with the "difficult" patient. PMID- 6919587 TI - Personalized care in the I.C.U. PMID- 6919589 TI - A practical nursing student speaks out. PMID- 6919594 TI - Communicating with developmentally disabled patients. PMID- 6919595 TI - Flexibility in nursing careers. PMID- 6919591 TI - Self-awareness - the key to a successful nurse-patient relationship? PMID- 6919590 TI - Loop diuretics. PMID- 6919593 TI - Guided imagination as an intervention in hopelessness. AB - Individual participants have returned to share the improvements made in scholastic and personal endeavors after continued use of the exercises/methods presented at the workshop. Other students requested repeated workshops/sessions directed toward reducing personal stress of negative expectations and for use with clients. Spreading the exercises over time appears to enhance integration and change. Future research is needed to document the efficacy of using imagery in nursing for students as well as for patients. For some clinical populations immediate results are often needed, for example those presenting with "giving up" behaviors in critical care areas. This concern remains for future research. It is speculated also that in the extreme of the data from this study, as evidenced in the unequal regression slopes, some significance may be hidden or masked. It is recommended that research continue utilizing academic as well as clinical populations identified as experiencing hopelessness. Indicators of short-term change must be developed and tested. It also is recommended that nurses interested in mind/body interaction pursue studies using imagery as a potential nursing intervention and begin the development of tools to document these interventions. Clients, staff, and students who experience hopelessness tend toward "giving up" behaviors. The purpose of this study was to investigate the effects of a workshop in guided imagination techniques on the condition of hopelessness. Although no statistically significant results can be reported from this study, nurses need to continue to develop imagery intervention techniques and to investigate, through research, the efficacy of these interventions. It is hoped that nurses in psychiatric and non-psychiatric settings will read the abundant, rich literature on the uses of imagery in the health sciences and will begin to explore the possibilities that exist for its application in nursing. PMID- 6919592 TI - The emergency room nurse and the psychiatric patient. PMID- 6919596 TI - Anorexia nervosa: choosing to starve. PMID- 6919597 TI - MMPI testing. PMID- 6919598 TI - Circumcision. PMID- 6919599 TI - Know your role. PMID- 6919601 TI - Therapeutic reminiscence in elderly patients. PMID- 6919600 TI - Gerontology in Sweden. PMID- 6919603 TI - The beat goes on. The famous tea party. PMID- 6919602 TI - Hot and cold therapy. PMID- 6919604 TI - LPN viewpoint. PMID- 6919605 TI - Elders and sexuality. PMID- 6919606 TI - Patient focus. PMID- 6919607 TI - My ileostomy surgery. PMID- 6919608 TI - RN & BSN for LPNs without campus classes. PMID- 6919609 TI - Human behavior: a testing of social skills. PMID- 6919610 TI - "Nurse, I can do it myself!". PMID- 6919611 TI - LPN viewpoint: should you climb the ladder? PMID- 6919612 TI - [Gastric and duodenal ulcers from the viewpoint of primary care]. PMID- 6919613 TI - [Physiopathology and therapy of gastric and duodenal ulcers--current trends]. PMID- 6919614 TI - [Psychosomatic viewpoint on the treatment and management of gastric and duodenal ulcers]. PMID- 6919615 TI - [Stress ulcer and its management]. PMID- 6919616 TI - [Physiopathology and management of complications of gastric and duodenal ulcers]. PMID- 6919617 TI - [Continued care and nursing of patients with gastric and duodenal ulcers--nursing intervention in the area of occupational health care]. PMID- 6919618 TI - [Nursing of a mother and her daughter, both hospitalized for stress ulcers of the stomach--a trial in a psychological approach]. PMID- 6919619 TI - [Nursing of gastro-duodenal ulcer patients at the development of perforation--re affirmation of the importance of shock prevention]. PMID- 6919621 TI - [Approach to a child with stress ulcer at a pediatric ambulatory clinic]. PMID- 6919620 TI - [Nursing of gastroduodenal ulcer patients during massive hematemesis and melena]. PMID- 6919622 TI - [Stress ulcer of children--its etiology and management]. PMID- 6919623 TI - [Conference: on nursing of a duodenal ulcer patient with stress-related problems]. PMID- 6919624 TI - [Nursing of patients with ulcerative colitis]. PMID- 6919627 TI - [Nursing diagnosis: observation. Significance and necessity of observation in nursing diagnosis]. PMID- 6919626 TI - [Rehabilitation exercises following mastectomy]. PMID- 6919625 TI - [Nursing of a patient with a colostomy drain--a case of ulcerative colitis]. PMID- 6919628 TI - [Nursing diagnosis: observation]. PMID- 6919629 TI - [Nursing diagnosis: observation. Observation in the diagnosis of liver diseases]. PMID- 6919630 TI - [Nursing diagnosis: observation. Observation at bedside and nursing planning observation of the patient with depression]. PMID- 6919632 TI - [Awareness of their illness by diabetic patients and problems of their diet therapy]. PMID- 6919631 TI - [An innovation in assistance of life activities of muscular dystrophy patients- utilization of their leisure time]. PMID- 6919633 TI - Dual actions of vanadate on high K-induced contraction in guinea-pig taenia coli. AB - Effects of vanadate (NH4VO3: VAN) on tension development, membrane potential and cellular Na content were investigated in guinea-pig taenia coli depolarized by 62.7 mM KCl solution. VAN (10(-4) - 10(-3) M) caused a transient increase in the K developed tension followed by a relaxation. The VAN-induced contraction was observed even in a low Ca (0.13 mM) solution but was inhibited by the removal of external Ca. After the addition of verapamil (5 x 10(-8), 10(-7) M). VAN still produced a contraction. Further, the VAN-induced contraction was observed in 142.2 mM KCl (Na 11.9 mM) solution containing ouabain (10(-4) M). On the other hand, the effect of VAN to relax the K-induced contraction was dependent on the concentration of VAN. In low Na (choline-substituted) solution, the VAN-induced relaxation was decreased. VAN increased cellular Na content of the depolarized muscle, and a correlation was obtained between the cellular Na accumulation and the relaxation. These results suggest that the relaxation is mainly attributable to the accumulation of Na following the inhibition of the Na pump, while the contraction is independent of the inhibition of the Na pump and less sensitive to the external Ca than the K-induced process. PMID- 6919634 TI - [Status of families caring for patients with senile dementia. A nationwide survey through the organizations of families with senile dementia patients]. PMID- 6919635 TI - [Regional care of patients with refractory diseases in Shinjuku-ku. A symposium]. PMID- 6919636 TI - [On the NHS in Scotland and Denmark (1)--dental care]. PMID- 6919637 TI - [Home nursing of a spinal cord injury patient: difficulties facing a severely handicapped person at home (1)]. PMID- 6919638 TI - [Public health nurses and mental health activities with special emphasis on day care]. PMID- 6919639 TI - [Organized activities by families caring for patients with senile dementia. Discussion: a need for assistance by public health nurses, an appeal by the families]. PMID- 6919640 TI - [Problems in geriatric health policies]. PMID- 6919641 TI - [Regional geriatric health activities]. PMID- 6919642 TI - [Health and diseases of the aged]. PMID- 6919643 TI - [Language disorders following stroke and their treatment]. PMID- 6919645 TI - [Work therapy for the aged]. PMID- 6919646 TI - [Problems of the aged in the future]. PMID- 6919644 TI - [Physical therapy for the aged at home]. PMID- 6919647 TI - [The system of public health nurse assignment in Hanagawa Prefecture and its background]. PMID- 6919650 TI - [Inaccessibility and possible potentials of the public health clinic: a lesson in public health nursing assignment]. PMID- 6919649 TI - [The common ground for the permanently assigned public health nurses and those assigned from the prefectural government: an observation of Yugawaramachi]. PMID- 6919648 TI - [Experiences of the public health nurses assigned to towns and villages of Kanagawa Prefecture. Discussion]. PMID- 6919652 TI - [Significance of public health nursing assignment: discussion]. PMID- 6919653 TI - [Overview of the public health nursing assignment system]. PMID- 6919651 TI - [Familiarity of the public health nurse with the public health clinic: a lesson in public health nursing activities at Kiyokawa-mura]. PMID- 6919655 TI - [Difficulties of a severely handicapped patient living at home: a lesson in home nursing of a patient with a spinal cord injury. (2)]. PMID- 6919654 TI - [The NHS in Scotland and Denmark (8). The NHS in Scotland]. PMID- 6919656 TI - [Strong backup by the public health clinic: a lesson in the public health nursing assignment]. PMID- 6919657 TI - Maternity-patient teaching--a nursing priority. AB - The overall positive response of the parent participants has validated the utility of the program. Future program expansion and revision will be based on social and technological change. Participant responses to the program will be monitored continually to determine whether their needs are being met. The program clarified the role nursing personnel have in teaching maternity patients. It serves to increase the new parents' self-confidence in being able to adjust to their new roles. One possible future expansion of the program might be post discharge group discussion sessions, supervised by nursing personnel. During those sessions, mothers could discuss feelings that they are experiencing, any difficulties they may have adapting to their new roles, and other topics they feel are relevant. Nurses would attend these sessions to serve as resource persons and group facilitators. The need for patient teaching in obstetrics is being recognized increasingly as a priority by health professionals in the field of maternal-child health. A concise and accurate means of documentation is necessary to ensure that consistent, comprehensive instructions are given to all new parents. PMID- 6919658 TI - Nursing care in the neonatal intensive care unit. PMID- 6919660 TI - Early postpartum discharge. PMID- 6919659 TI - Maternal-infant attachment in a traditional hospital setting. AB - All changes were implemented by nurse-midwives and staff nurses. Some of the changes required administrative or medical concurrence, but all were initiated by nurses. Nursing administration was supportive and encouraged the staff nurse. It took courage and determination to implement changes described. The biggest hurdle was to overcome the attitude that nothing at the hospital could ever change. Once that attitude was overcome, the actual changes in routine and policy were made with a minimum of difficulty. It is inexcusable not to encourage maternal-infant attachment because the setting is less than ideal. Women, infants, and families benefit too much from this initial contact for nurses top sit back and wait for hospital policy to change, the ABC to open, or the new wing to be built. In addition, there is so much joy and satisfaction in assisting in the development of a positive relationship between a mother and her newborn that the nurse should avail herself of the opportunity to do so. PMID- 6919661 TI - Prenatal education for adolescents in a delinquent youth facility. PMID- 6919662 TI - Which prepared-childbirth coping strategies are effective? AB - To investigate coping strategies taught in childbirth education classes, a study was conducted to nulliparous women immersing their hands in ice water. Length of tolerance and self-reported pain served as measures of the techniques' effectiveness. Results in Experiment 1 showed structured breathing to be more effective than normal breathing. Effleurage was less helpful than no effleurage. Practice under stress was better than either imaginal practice or no practice. In Experiment 2 a combination of structured breathing and attention focal points was much better than normal breathing. While coaching was better than no coaching, the combination of structured breathing, attention focal points, and coaching produced the strongest treatment. PMID- 6919663 TI - Unscholarly reports? PMID- 6919665 TI - [Have technical aspects of childbirth gone to extremes?]. PMID- 6919664 TI - Effectiveness of breast self-examination teaching to women of low socioeconomic class. AB - To assess the effect of a breast self-examination (BSE) teaching program on retention of BSE knowledge and accuracy of BSE performance among women of low socioeconomic class, a pretest-posttest control group design with random assignment to groups was given to women at a Southeastern urban clinic. One hundred eighty women were pretested, after which the experimental group (N = 89) received one-to-one BSE instruction. Seventy of the subjects were given a posttest approximately two months later. All subjects were then asked to demonstrate BSE on themselves. The experimental group subjects showed a significantly greater increase in BSE knowledge from pretest to posttest and performed BSE with greater accuracy than the control group. PMID- 6919666 TI - [Sexual problems in marital life and childbirth]. PMID- 6919668 TI - [Nursing care at the maternity hospital seen as part of maternal health care]. PMID- 6919667 TI - [Family planning and contraception]. PMID- 6919669 TI - [Soviet day care center--goals and methods]. PMID- 6919670 TI - [Profile: Ms. Taeko Kinjo who was awarded Asahi Social Welfare Prize for her contribution to health and welfare of the population in Okinawa]. PMID- 6919671 TI - [Swan-Ganz catheter]. PMID- 6919673 TI - [Formulation of teaching manpower in nursing education: an observation on the hours spent in clinical training]. PMID- 6919672 TI - [Statistical file: the number of nursing personnel currently in employment (at the end of 1980)]. PMID- 6919674 TI - [New definition of nursing: a social policy statement by the American Nursing Association (3)]. PMID- 6919676 TI - [Nursing dilemma faced by individual nurses]. PMID- 6919675 TI - [Social positions and evaluation of nurses in the modern history of nursing in Japan. 23]. PMID- 6919677 TI - [Nursing ethics in daily nursing practice: a support for the conscious effort by the nurse]. PMID- 6919678 TI - [Nursing dilemma: discussion]. PMID- 6919679 TI - [Bio-ethics in the United States]. PMID- 6919680 TI - [Report on the mechanical life support project: a response to the discussion guideline proposed by the ICN subcommittee]. PMID- 6919682 TI - [Medical topics: constipation and breast cancer]. PMID- 6919683 TI - [Medical topics: Balkan nephropathy]. PMID- 6919684 TI - [Occupationally-induced diseases of the bronchi]. PMID- 6919685 TI - [When you ask the nurse: hay fever patients must forgo a lot of things]. PMID- 6919686 TI - [The problem of "test-tube babies"]. PMID- 6919687 TI - [Incisive decision. Position of the German Nursing Association]. PMID- 6919681 TI - [Life history of a public health nurse working among frontier farmers of Hokkaido]. PMID- 6919688 TI - [Sick because of the hospital]. PMID- 6919690 TI - [Meniscus lesions]. PMID- 6919689 TI - [Memory and its disorders]. PMID- 6919691 TI - A suggested modification of the Rustia School Health Promotion Model. PMID- 6919692 TI - Conceptual questions in health education and philosophical inquiry. PMID- 6919693 TI - Reye's syndrome: a review of research studies. PMID- 6919694 TI - Beyond the basic four: what does Johnny know about nutrition? PMID- 6919695 TI - An investigation of cardiovascular disease risk factors in an adolescent population. PMID- 6919696 TI - Randomized response: a technique for improving the validity of self-reported health behaviors. PMID- 6919697 TI - The effects of a high school stress management unit on student's heart rate and muscle tension. PMID- 6919698 TI - Using meta analysis in health education research. PMID- 6919699 TI - 1981 keynote address: American School Health Association. PMID- 6919700 TI - Attitudinal and social normative factors as predictors of intended alcohol abuse among fifth- and seventh-grade students. PMID- 6919703 TI - Are your students learning in a safe environment? AB - Whenever numerous people gather in a limited area the chances for unsafe conditions exisitng increase. A school building is no exception. Each year the results of unsafe conditions in school settings show up in national accident statistics. By law, school districts are required to provide a safe school environment. Specifically, each teacher is responsible for providing a safe learning environment. To help teachers become more aware of a safe environment the authors have developed a self-awareness checklist. PMID- 6919701 TI - The impact of long-term dental health education on oral hygiene behavior. PMID- 6919702 TI - Hirschi's bond theory, juvenile delinquency and the school nurse. PMID- 6919705 TI - Adolescence: the transition years. PMID- 6919706 TI - Problem behavior and developmental transition in adolescence. PMID- 6919704 TI - The whole person concept as a part of the elementary school health education program. PMID- 6919708 TI - Enhancing the transition years: the challenge of adolescent health promotion. PMID- 6919707 TI - Social adaptation to first grade and teenage drug, alcohol and cigarette use. PMID- 6919709 TI - Radio: a tool for health educators. PMID- 6919710 TI - Changing times in school nursing. PMID- 6919711 TI - Affective education - a two-sided coin. PMID- 6919712 TI - [On the educational goals in relation to postgraduate education]. PMID- 6919713 TI - [Problems concerning achieving goals in basic nursing courses at the end of the program]. PMID- 6919714 TI - [Expectations and requirements for training degree of nursing arts at the end of the program for basic training of nursing]. PMID- 6919715 TI - [Evaluation of the extent of basic nursing technology knowledge at the end of the program at our school--self-evaluation by the students and a survey of frequencies of clinical training sessions]. PMID- 6919718 TI - [Specific behavioral objectives in continuing education]. PMID- 6919717 TI - [Scientific and ethical approaches to human reproduction. Discussion]. PMID- 6919716 TI - [Elementary and basic items in nursing technology training]. PMID- 6919719 TI - [The present nursing education]. PMID- 6919720 TI - [Interactions between the instructor and students at a clinical conference--with special reference to nursing of a patient with primary liver cancer (1)]. PMID- 6919721 TI - [Teaching method applying problem-solving in education of nursing technology--a trial in paper simulation]. PMID- 6919722 TI - [Continuing education of licensed practical nurses--based on education at the practical nursing course, Osaka Medical Association School of Nursing]. PMID- 6919724 TI - [Clinical description and therapy of pain]. PMID- 6919723 TI - [Nature and mechanism of pain]. PMID- 6919726 TI - [Nursing of a patient complaining of pain: a case study]. PMID- 6919725 TI - [Nursing process for a patient reporting pain]. PMID- 6919727 TI - [Nursing process: nursing of a patient with pain. Discussion: evaluation of a nursing process]. PMID- 6919729 TI - [Nursing process: possibilities and limitations in planned practice (8). Evaluation of the procedure in each process: planning (2)--selection of a method for solving the problem]. PMID- 6919728 TI - [Bedside examination: keypoints in nursing and interpretation of data. Examination of the circulatory system (1): types of cardiac examinations and their methods. Electrocardiography and simple thoracic radiography in the routine diagnosis]. PMID- 6919731 TI - [Experimental evaluation of moist heat treatment--on technics based on water temperature and effective duration in two different seasons]. PMID- 6919730 TI - [Nursing of a leukemia patient unable to achieve total remission in spite of extended therapy]. PMID- 6919733 TI - [In search of new nursing philosophy. XIX. The "life": transcending suffering]. PMID- 6919732 TI - [In search of humane nursing. Nursing of a patient with liver cirrhosis with difficulty in relating to the nurse]. PMID- 6919734 TI - [Mechanism and conditions for gentleness]. PMID- 6919735 TI - [Hypertension and pregnancy]. PMID- 6919736 TI - [Hydatid mole]. PMID- 6919737 TI - [Use of hyperbaric oxygenation in obstetrics and gynecology]. PMID- 6919738 TI - [Uterine developmental defects and pregnancy]. PMID- 6919739 TI - [Clinical course and diagnosis of developmental defects of the internal genitalia during sexual maturation]. PMID- 6919740 TI - [Effect of alcohol on the fetus]. PMID- 6919741 TI - [Psychotherapy of pregnant women]. PMID- 6919742 TI - [Psychosomatic disorders in the premenstrual period]. PMID- 6919743 TI - [Work of a neonatal pathology ward]. PMID- 6919746 TI - [Reference service in a maternity hospital]. PMID- 6919745 TI - [Tasks of an automatic audiometry office]. PMID- 6919744 TI - [Role of the nurse in caring for premature infants]. PMID- 6919747 TI - [Functional obligations of the nurses in a gynecologic hospital]. PMID- 6919748 TI - [Harm of smoking]. PMID- 6919749 TI - [Work of the nurses' council of the Chelyabinsk City First Aid Hospital]. PMID- 6919752 TI - Screening of the well elderly in general practice. PMID- 6919750 TI - [Ovarian apoplexy]. PMID- 6919751 TI - Interaction with health care personnel. Part 2: Hospital maternity care. PMID- 6919753 TI - About gastroenteritis. PMID- 6919754 TI - Nurses and the Brandt Report. PMID- 6919755 TI - Implications of the sexual revolution. PMID- 6919756 TI - Surgical wound management with Op-site - a new and preferred method. PMID- 6919758 TI - Planning operating departments No. 1. The nursing role. PMID- 6919757 TI - "Negligent delegation - where does it begin and end?". PMID- 6919759 TI - Clathrin locks up vesicle structure. PMID- 6919761 TI - The proposed reimbursement regulation. PMID- 6919760 TI - Biosynthesis of membrane factor B by mouse peritoneal macrophages. AB - The biosynthesis of many of the complement proteins by cells of the monocyte macrophage series has been established. Studies on these cells using radiolabelled amino acids demonstrated synthesis of precursor proteins (pro complement), and the native complement protein similar in size to that found in the plasma. However, synthesis of membrane complement proteins has not been demonstrated, although it has been suggested by previous studies using indirect techniques. In particular, there is evidence for the membrane-associated factor B in human lymphocytes. We report here that resident and thioglycollate-stimulated mouse peritoneal macrophages synthesized, in short-term primary cultures membrane factor B of molecular weight (MW) 95,000 and secreted factor B (MW 90,000) as single chain polypeptides. We also found a large single chain polypeptide with an approximate molecular weight of 195,000, which may be the putative factor B precursor. PMID- 6919764 TI - Computer leasing investments provide two-income families inflation hedge, added revenue. PMID- 6919762 TI - Hemodialysis of adolescents in end stage renal disease. PMID- 6919763 TI - Getting back to reality: psychosocial adjustments in CAPD. PMID- 6919765 TI - Early experiences with the Hemasite Vascular Access Shunt. PMID- 6919767 TI - Facility report: Shands Teaching Hospital and Clinics, Gainesville, Florida. PMID- 6919768 TI - Hemodialysis emergencies: carefully planned resuscitation. PMID- 6919766 TI - Suspecting and detecting sepsis in the dialysis patient. PMID- 6919770 TI - Changing concepts of morbidity and mortality in the elderly population. PMID- 6919769 TI - Crisis theory: application and utilization with hemodialysis patients and families. PMID- 6919772 TI - Health maintenance organizations and the rationing of medical care. PMID- 6919773 TI - Certificate of need and low capital-cost medical technology. PMID- 6919771 TI - Community health centers: an initiative of enduring utility. PMID- 6919774 TI - Exploring a paradox: belief in a crisis and general satisfaction with medical care. PMID- 6919776 TI - Disseminated intravascular coagulation. PMID- 6919777 TI - I.V. nursing--skin sensitivity testing interface. PMID- 6919775 TI - Motivation. PMID- 6919778 TI - External degree: fact not fallacy. PMID- 6919780 TI - Reflections on being a technical advisor for NURSE. PMID- 6919781 TI - Change is a challenge. PMID- 6919779 TI - New concepts in microaggregate filtration. PMID- 6919783 TI - Do patients understand patient-education brochures? PMID- 6919782 TI - Grassroots political action: organizing a legislator's day. PMID- 6919784 TI - Teaching sexuality as a nursing elective. PMID- 6919785 TI - Advocacy: what is it? PMID- 6919786 TI - Nursing homes for initial clinical experience: some specific advantages. PMID- 6919787 TI - Test your knowledge of fluid and electrolyte management--Part 2. PMID- 6919788 TI - Deciphering diagnostic studies: bronchoscopy. PMID- 6919789 TI - Medication errors: check carefully before administering a prefilled lidocaine syringe. PMID- 6919791 TI - How you can really help the drug-abusing patient. PMID- 6919790 TI - Emergency! First aid for cardiopulmonary arrest. PMID- 6919793 TI - Botulism. PMID- 6919792 TI - You can control cancer pain with drugs but the proper way may surprise you. PMID- 6919794 TI - We had to help Katie adjust her expectations. PMID- 6919795 TI - Hope and flexibility: your keys to helping OBS patients. PMID- 6919797 TI - Fear of floating to an orthopedic unit. PMID- 6919796 TI - Teaching families to give trach care at home. PMID- 6919798 TI - Thoracic emergencies. PMID- 6919799 TI - [Communication and the helping relationship: elements of nursing competence .1]. PMID- 6919800 TI - [Contraception in adolescence]. PMID- 6919802 TI - [Matamoros mix]. PMID- 6919801 TI - [The Quebec Nurses' Association, simply an interest group or a real pressure group?]. PMID- 6919803 TI - [The aged person. The impact of hospitalization of a chronically ill patient on the family and his expectations of the hospital center and the receiving center]. PMID- 6919804 TI - [The aged... an unloved class of benificiaries]. PMID- 6919805 TI - [Geriatric nursing]. PMID- 6919806 TI - [Communication and the helping relationship: elements of nursing competence. 2]. PMID- 6919808 TI - [Overconsumption of drugs]. PMID- 6919809 TI - [Sexuality in the 3d age]. PMID- 6919810 TI - ["Subsisting" through continuous ambulatory peritoneal dialysis]. PMID- 6919811 TI - Avoiding cultural myopia: what the Japanese can teach nurses about management. PMID- 6919807 TI - [Professional licensure examination: new since August 1981]. PMID- 6919812 TI - "It's a small world after all": nursing leadership from an international perspective. PMID- 6919814 TI - Action strategies for the 1980s: overview of current nursing administration issues. PMID- 6919813 TI - The teaching of ethical decision-making in schools of nursing. PMID- 6919815 TI - Making the most of every minute: reminders for nursing leaders. PMID- 6919816 TI - Management structures--the next step. PMID- 6919817 TI - Management information in health visiting. 1. PMID- 6919818 TI - The management of clinical specialties. 3. Care of the dying patient at home. PMID- 6919819 TI - Facing retirement: is it any different for the nursing profession? PMID- 6919821 TI - Misconceptions of a CC manager. PMID- 6919820 TI - New careers advisory service: post-basic training--paediatrics. PMID- 6919823 TI - Motivating others. PMID- 6919822 TI - PSRO: the hospital manager's role. PMID- 6919824 TI - Managing conflict: comparing strategies and their use. PMID- 6919825 TI - A marginal punch-sort system: organize our references. PMID- 6919826 TI - Health information brokers. PMID- 6919827 TI - Teaching & evaluating nursing management. PMID- 6919828 TI - Law for the nurse manager: are side rails necessary? PMID- 6919830 TI - Children are family, too! PMID- 6919829 TI - Art & science of management: philosophy for nurses? PMID- 6919832 TI - Which dressing? PMID- 6919831 TI - Nurses' self-image. PMID- 6919833 TI - OH services to small industries. PMID- 6919834 TI - Safety training 2: categories of training. PMID- 6919835 TI - Changing lifestyles: a wellness approach. PMID- 6919836 TI - Work, stress, and health: four major conclusions. PMID- 6919838 TI - Wellness in the workplace. PMID- 6919837 TI - Kimberly-Clark's health management program. PMID- 6919839 TI - Well versus not sick. PMID- 6919840 TI - Getting straight. PMID- 6919841 TI - A method of monitoring reproductive outcome for workplace reproductive hazards. PMID- 6919842 TI - Planning for the hypertensive employee in industry. PMID- 6919844 TI - Women, work and health. PMID- 6919843 TI - Employees' problems assistance program. PMID- 6919846 TI - Transforming occupational health care. PMID- 6919845 TI - Nursing directives for nursing. PMID- 6919847 TI - Drugs and dosages. Zovirax - Dolobid - Valrelease. PMID- 6919849 TI - [The place of work: who helps the nurse?]. PMID- 6919848 TI - Women/nurses in 1982: how are we doing? PMID- 6919851 TI - [Health in old age: myths and reality]. PMID- 6919853 TI - Criteria for the evaluation of diploma programs in nursing. PMID- 6919854 TI - Course development in schools of nursing. PMID- 6919852 TI - [Nursing--an ethical sphere of action]. PMID- 6919850 TI - [Special education in nursing at the university]. PMID- 6919856 TI - Factors influencing the placement of courses in the curriculum plan. PMID- 6919855 TI - Factors influencing course development. PMID- 6919857 TI - Essential characteristics of a course in nursing. PMID- 6919858 TI - The development of a course outline. PMID- 6919859 TI - A study of the NLN accreditation program. PMID- 6919860 TI - Employment, mobility, and personal characteristics of nurses newly licensed in 1980: state summaries, Volume 1. PMID- 6919861 TI - NLN position statements. PMID- 6919862 TI - Speaking out on piracy. PMID- 6919863 TI - Nursing education for college graduates. PMID- 6919864 TI - Collaborative practice models in community health nursing. PMID- 6919865 TI - Issues in competency-based testing. PMID- 6919866 TI - Associated degree nursing: faculty preparation and commitment. PMID- 6919867 TI - The new state board exam. PMID- 6919869 TI - End paper: a celebration of nursing. PMID- 6919868 TI - When former students fail state boards. PMID- 6919870 TI - Sexual harassment in nursing. PMID- 6919871 TI - Women and the fear of being envied. AB - Nursing is very much concerned with the health and status of women. Perhaps at the same time we are attempting to work therapeutically with this very large portion of humankind, it would be beneficial for us to more closely analyze our own difficulties as a profession made up almost exclusively of women. What is the relationship between the level of our self-esteem and our problem with envy--envy of and fear of being envied by other nurses and health care providers? In terms of professional achievement, to what extent is fear of success related to fear of being envied? Lastly, if we open the affective windows and allow some honest dialogue to blow through about a subject we tend to repress, will we be able to outgrow our "one-down" position? PMID- 6919872 TI - Clinical evaluation--an instructor's dilemma. PMID- 6919873 TI - Entering the mysterious dimension of other: an existential approach to nursing care. PMID- 6919874 TI - Homeless women. PMID- 6919875 TI - End paper: in principle. PMID- 6919876 TI - Licensure laws in transition. PMID- 6919877 TI - Public health nursing practice - an educator's view. PMID- 6919878 TI - Public health nursing practice - an administrator's view. PMID- 6919879 TI - An experience in collaborative research. PMID- 6919880 TI - Establishment of a nursing clinic for faculty and student clinical practice. PMID- 6919881 TI - Conceptual issues in nursing. PMID- 6919882 TI - Sharing a faculty position. PMID- 6919884 TI - Client care-seeking behaviours in a community setting and their sources of satisfaction with nursing care. PMID- 6919885 TI - Patterns of concern in hospitalized chronically-ill young children: a preliminary report. PMID- 6919883 TI - Network: up the ladder of success. PMID- 6919886 TI - Community health assessment: a systematic approach. PMID- 6919887 TI - Growth and development--for elders: reminiscence, an underused nursing resource. PMID- 6919888 TI - Microbial decontamination in hospitals. PMID- 6919889 TI - Last offices in cases of notifiable disease. PMID- 6919891 TI - The community psychiatric nursing service at Prestwich Hospital. PMID- 6919892 TI - Racism in nursing. PMID- 6919890 TI - Resource booklet--'Infection and its control'. PMID- 6919893 TI - The normal embryological development of the heart. PMID- 6919894 TI - Renal replacement therapy. 3-1. Haemodialysis equipment. PMID- 6919896 TI - Building for the future. PMID- 6919895 TI - A patient with rheumatoid arthritis and joint tuberculosis. PMID- 6919897 TI - View from an inspectorate. Inspectorate of the General Nursing Council for England and Wales. PMID- 6919898 TI - Building for the future. 1. The future of education. PMID- 6919899 TI - Wound care No. 9. Wound infection - treatment. PMID- 6919900 TI - Building for the future: 2. A successful graft. PMID- 6919901 TI - Building for the future. 2. The bed of Procrustes. PMID- 6919902 TI - Whose NHS is it anyway? PMID- 6919903 TI - A chance to come together. PMID- 6919904 TI - Take me to your mentor. PMID- 6919906 TI - Food allergy or food allergic disease. PMID- 6919905 TI - Daniel's allergies. PMID- 6919907 TI - Sharing the pleasure and the pain. PMID- 6919908 TI - Education in action. PMID- 6919910 TI - A nurse bank with built-in training. PMID- 6919909 TI - Renal replacement therapy. 4-2. Continuous ambulatory peritoneal dialysis--an alternative approach in maintenance dialysis therapy. PMID- 6919912 TI - The nursing process and the professional status of nursing. PMID- 6919911 TI - What it's like being a bank nurse. PMID- 6919913 TI - Systems of life No 90. Systems and signs: nervous system. Testing motor function 1. PMID- 6919915 TI - A breath of fresh air. Interview by Yvonne Moores. PMID- 6919914 TI - Keep it in the family. PMID- 6919916 TI - The patient process. PMID- 6919917 TI - After-care of puerperal psychosis in the community. PMID- 6919918 TI - Self-appraisal in health. PMID- 6919919 TI - Pacemakers. PMID- 6919922 TI - Relatively speaking - 1. Helplessness and frustration: the relatives' dilemma. PMID- 6919920 TI - Losing sight of the grassroots? PMID- 6919921 TI - The consolation of elitism. PMID- 6919923 TI - Relatively speaking - 1. Communicating with families of cancer patients. 1. The relatives and doctors. PMID- 6919925 TI - Organising a clinic for artificial insemination by donor (AID). PMID- 6919926 TI - Symposium on obesity. PMID- 6919924 TI - Controlling absence. PMID- 6919927 TI - An overview of obesity: its significance to nursing: definition, prevalence, etiologic concerns, and treatment strategies. AB - This article has presented an overview of obesity. It has explored the significance of obesity to nursing today. The definition of obesity vis-a-vis overweight has been delineated. The psychological, physiologic and socioenvironmental causes of obesity were discussed. Finally, some of the important treatment strategies, past and current, were discussed, concluding that a combination of strategies are needed to treat this complex health problem caused by the interaction of several factors--environmental, physiologic in the form of predisposition, and psychological. The following articles provide the reader with an understanding of obese people and the specific nursing interventions associated with caring for these individuals. Whether the obese patient has a postoperative bypass or is a child in a school system within the community, the nurse's role must be based on an understanding of obesity, its causes, and current treatments. PMID- 6919928 TI - Implications, considerations, and nursing interventions of obesity in neonatal and preschool patients. PMID- 6919930 TI - Obesity of women during the childbearing years: psychosocial and physiologic aspects. PMID- 6919931 TI - Obesity in the aged: not just a case of overeating. PMID- 6919929 TI - Obesity and the school-age child. AB - The need for nursing involvement in the care of the obese school-age child and his family has been identified. The use of the nursing process based on the MSI Model of nursing has been discussed. The nurse plays an important role in identifying overweight children and in working with these children and their families when the need arises. the focus of nursing care may be preventing future weight gain, weight reduction, or regain after reduction. Linda, the obese child in Blubber, was ridiculed by her peers. This is a common, everyday experience for the obese child. It is hoped that the obese school-age child will have a better success rate for weight reduction and will ultimately be able to maintain the weight loss through the interventions of a professional nurse who uses this holistic approach to nursing care. PMID- 6919934 TI - Symposium on drugs and the older adult. PMID- 6919933 TI - The surgical treatment of morbid obesity: implications and interventions. PMID- 6919935 TI - Normal changes in aging and nursing implications of drug therapy. AB - Safe and effective pharmacotherapy of the elderly goes far beyond the mechanical safeguards for administering the right drug to the right patient at the right time. A broad knowledge of cell membrane dynamics as reviewed here and how they are related to the processes of drug disposition provide baseline data used for monitoring drug action and drug-user responses. However, each period of the life span has its own particular characteristics that may qualify expected drug response unless standard drug regimens area adjusted and individualized. Normal changes in body structure and function imposed by the aging process require special attention, for while the patient may be in a steady state, age-related reduction in range of homeostatic processes leads to varied levels of drug response and changed susceptibility to drug reactions. Appreciation of these qualifiers of pharmacotherapy can help to reduce the high incidence of drug related illnesses in the aged. PMID- 6919936 TI - Cardiovascular drugs and the older adult. AB - This case is typical of cardiovascular drug regimens in the elderly. Indeed, patients are often on several additional drugs for cardiovascular problems as well as other diseases. Familiarity with the pharmacology of all drugs is mandatory. Interactions of drugs can be complex, and a clinical pharmacologist can be a helpful resource. The classic interaction in cardiovascular drug regimens, as in this case, is with the combination of digoxin and potassium depleting diuretics. The special interactions of cardiovascular and psychotropic drugs will be discussed elsewhere in this symposium. General clinical concerns in the care of patients taking cardiovascular drugs include scrutiny of drug choice, dosage, and combination. The dosage of drugs may need to be altered as the client ages. Drug types and combinations also may need to be changed to meet the needs of the patient's altered physiologic responses. The patient's response to drug therapy must be continuously evaluated. The best rule is to ensure that the patient takes the least number of drugs at the minimum dose required for desired effects. Starting drug dosages low and increasing them gradually often prevent toxicity. The nurse's assessment of subtle behavior or physical changes is important for the early detection of toxicity and adverse reactions. The possibility that a noted change is drug precipitated should always be considered. Health education of the client, family, or appropriate others is a significant nursing contribution to care. Awareness of drug side effects and specific offsetting interventions can prevent many discomforts and complications. Often making the patient aware of his changing body needs helps to elicit cooperation. PMID- 6919932 TI - Reducing cardiac risk factors in the obese patient. AB - The holistic, self-care approach for permanent weight control can be used to reduce cardiac risk factors in the obese yo-yo dieter. Two major concepts of the approach are implied by the name: holistic means that all parts of the patient's life are examined and incorporated into an adjustment in lifestyle to promote not only permanent weight control but also reduced cardiac risk as well. Self-care implies that the patient is ultimately responsible for his change in lifestyle. The nurse can only act as a knowledgeable, supportive facilitator to the patient. However, if the patient over an extended period of time chooses to adopt a new healthier lifestyle, the nurse can be one of the greatest influences in accomplishing positive change. PMID- 6919937 TI - Helping elderly patients in ambulatory settings cope with drug therapy. PMID- 6919939 TI - Assisting the elderly with drug therapy in the home. PMID- 6919938 TI - Promoting effective drug-taking behavior in the elderly. AB - Nurses who wish to promote effective drug-taking behavior in their elderly patients must first enhance their knowledge of the required adaptations in education for older patients. Identification of patients' learning needs and factors affecting learning in the aged have been presented. Numerous strategies, based on current research and theory, were suggested. Goals for learning must be set with the patient. Teaching strategies should be individualized throughout the entire medication teaching program. The time spent in these endeavors will be worth the outcome: safer and more effective self-medication by the older adult. PMID- 6919940 TI - Psychotropic drugs and the elderly patient. PMID- 6919942 TI - A survey of H.D. control work. PMID- 6919941 TI - Misuse and abuse of prescription and nonprescription drugs by the elderly. PMID- 6919943 TI - Social science in nursing education and research. PMID- 6919944 TI - Curriculum change in nursing. VI. An example of community health-orientation. PMID- 6919945 TI - A manager's guide to management. PMID- 6919946 TI - Issues in nursing. 6. A cure for all ills? PMID- 6919947 TI - Issues in nursing. 6. When sticky plaster is not enough. PMID- 6919949 TI - Anaesthetic nursing: getting through the list. PMID- 6919948 TI - Grading calm before the storm? PMID- 6919951 TI - Postbasic nursing procedures. 7. Irrigating the ear. PMID- 6919952 TI - Nursing homes: small is beautiful for the elderly. PMID- 6919950 TI - A poor record in writing. PMID- 6919953 TI - Classifying disease. PMID- 6919954 TI - Nursing care, American style. PMID- 6919955 TI - A neuromuscular approach. 6. Safety first. PMID- 6919957 TI - How one family devotes itself to the care of the mentally handicapped: the mother's story. PMID- 6919956 TI - Retained placenta: triumph on the sand. PMID- 6919958 TI - How one family devotes itself to the care of the mentally handicapped: the son's perspective. PMID- 6919959 TI - How one family devotes itself to the care of the mentally handicapped: the daughter with a tradition to follow. PMID- 6919960 TI - Careers: plastic surgery nursing. More than hard graft. PMID- 6919961 TI - Practice nurses: the practice nurse grows up. PMID- 6919962 TI - Practice nurses: accountability writ large. PMID- 6919963 TI - Depression: an anxious time. PMID- 6919965 TI - Postbasic nursing procedures. 8. Neonatal serum bilirubin. PMID- 6919966 TI - Endoscopy: inside information. PMID- 6919967 TI - There's no degree of danger. PMID- 6919968 TI - Community care: a day in the life of. PMID- 6919964 TI - Degree from Texas: back to school. PMID- 6919969 TI - Accident and emergency: an overdose of attitudes. PMID- 6919970 TI - Closing in on change. PMID- 6919971 TI - Nursing care study: a fighter from failure. PMID- 6919972 TI - Approaching death: an experience we all have to face. PMID- 6919973 TI - Cytology: out of the ordinary. PMID- 6919974 TI - Anytown anecdotes. 12. The farewell party. PMID- 6919975 TI - Careers: ophthalmic nursing. Seeing a need. PMID- 6919976 TI - Clinical forum 6. Burns: Identity crisis. PMID- 6919977 TI - Clinical forum 6. Burns: a family affair. PMID- 6919978 TI - Clinical forum. 6. Burns: a special kind of caring. PMID- 6919979 TI - Kirkcaldy Nurses' Home fire: countdown to tragedy. PMID- 6919981 TI - Pressure at work. Warning: hospitals can damage your health. PMID- 6919980 TI - Regional mortality rates: death in the north west. PMID- 6919982 TI - Yours truly weighs in. PMID- 6919983 TI - Postbasic nursing procedures. 9. Catheterisation. PMID- 6919984 TI - A simple test for cancer. PMID- 6919985 TI - Spina bifida: the best possible start. PMID- 6919986 TI - Fluid balance. PMID- 6919987 TI - Why psychiatric nurses should be heart by the politicians. PMID- 6919988 TI - Sexual behaviour: falling interest. PMID- 6919989 TI - Stop taking liberties. PMID- 6919990 TI - Careers: special clinics. The microbe hunters. PMID- 6919991 TI - The battle victims come home. PMID- 6919992 TI - A long journey ends for 51 men. PMID- 6919993 TI - Psychiatry/mental handicap forum. 6. Contending with violence on the wards. PMID- 6919994 TI - Psychiatry/mental handicap forum. 6. Security: a safe and therapeutic environment. PMID- 6919995 TI - Sickness rates: absent without leave. PMID- 6919996 TI - Mother-baby relationship: 'I feel nothing'. PMID- 6919997 TI - Postbasic nursing procedures. 10. Plaster cast 1. PMID- 6919998 TI - Management: the Bloomsbury set. PMID- 6919999 TI - Anytown anecdotes. 13. Picking up the threads. PMID- 6920001 TI - I accuse nursing's leaders of lacking wisdom and vision. PMID- 6920002 TI - Handling patients. 1. Safely does it. PMID- 6920003 TI - Stop pandering to doctors. PMID- 6920004 TI - Off with the old. PMID- 6920005 TI - Midwifery education in Wales: it's time for a break. PMID- 6920000 TI - But I liked wearing a mask. PMID- 6920007 TI - Operating department assistants: leave it to the specialists. PMID- 6920006 TI - Careers: family planning, fundamental to care. PMID- 6920009 TI - Adjusting to motherhood. PMID- 6920008 TI - Peace comes too late for burn victims to escape mental and physical scars. PMID- 6920010 TI - A conflict of roles: cesarean section. PMID- 6920011 TI - Breast feeding: a recipe for success. PMID- 6920012 TI - Breast feeding counselor: time to talk. PMID- 6920013 TI - Breast feeding: with a little help from my friends. PMID- 6920014 TI - Complications of the puerperium. PMID- 6920015 TI - Stillbirth. PMID- 6920018 TI - The biology of ageing. 1: a gradual process. PMID- 6920017 TI - Scottish nurse education: a touch of Celtic class. PMID- 6920016 TI - Unemployment in human terms. PMID- 6920019 TI - Young, gifted...and a mother. PMID- 6920020 TI - Pacemakers. 1: idyllic, spacious and sophisticated. PMID- 6920021 TI - How far should further education go? PMID- 6920022 TI - Fetal scalp electrodes: beating distress. PMID- 6920023 TI - Issues in nursing. 7. Issues is midwifery: don't ignore those government documents. PMID- 6920024 TI - The obstetrics of fear. PMID- 6920025 TI - Reorganisation: reject the easy way out. PMID- 6920026 TI - Nursing care study. Walking was a painful business. PMID- 6920027 TI - Employment law. 2: get it down in writing. PMID- 6920028 TI - Between the jelly and the jam...reflections of a Minnesota nurse working as an "English" nurse. PMID- 6920029 TI - Careers: endoscopy nursing: an inside view. PMID- 6920031 TI - Helping the new amputee. PMID- 6920030 TI - Nursing care of the amputee: an overview. PMID- 6920033 TI - Musculoskeletal assessment: gait assessment. PMID- 6920032 TI - Coping with chronic pain in rheumatoid arthritis: patient behaviors and nursing interventions. PMID- 6920034 TI - A review of muscle atrophy. PMID- 6920036 TI - [Rational family nutrition]. PMID- 6920035 TI - [Kallikrein-kinin system of blood in patients with nocturnal paroxysmal hemoglobinuria undergoing complex treatment with with heparin]. PMID- 6920037 TI - [When does the patient get better?]. PMID- 6920038 TI - [Voice in the discussion]. PMID- 6920039 TI - [Section regulations]. PMID- 6920040 TI - [Development of scientific nursing personnel]. PMID- 6920041 TI - [Nursing process: the evaluation of operations]. PMID- 6920043 TI - [School days]. PMID- 6920042 TI - [In full voice]. PMID- 6920044 TI - [There may be no end of patients, if only...]. PMID- 6920045 TI - [Voice in the discussion]. PMID- 6920046 TI - [Male sterility]. PMID- 6920047 TI - [Period of fertility and infertility]. PMID- 6920048 TI - [Epidemic conjunctivitis]. PMID- 6920049 TI - [Scabies]. PMID- 6920050 TI - [Independent nursing section has started work in the agency]. PMID- 6920051 TI - [Work and wages]. PMID- 6920052 TI - Assessment of self-care readiness. PMID- 6920053 TI - The role of the insurance rehabilitation nurse. PMID- 6920055 TI - [Face to face: nurse educators and public authorities]. PMID- 6920054 TI - The health education needs of the adult with epilepsy. PMID- 6920056 TI - [Wrapping is not sterilizing]. PMID- 6920057 TI - [The Bagneux Club: an experiment to watch]. PMID- 6920058 TI - [Each to his own ... or the course of the heart 1982]. PMID- 6920059 TI - [No tender age for little people]. PMID- 6920063 TI - [Tuberculosis: screening and prevention in 1981]. PMID- 6920062 TI - [Blood transfusion: equipment]. PMID- 6920060 TI - [Initial care to burn patients]. PMID- 6920061 TI - [Blood transfusion. 2. Blood derivatives and plasma fractions]. PMID- 6920064 TI - [The 'Old Man' of La Noue]. PMID- 6920065 TI - [Femoral neck fractures]. PMID- 6920066 TI - [Metrorrhagia during the period of genital activity]. PMID- 6920067 TI - [Hemodialysis: technical and psychological aspects of the patient and the nurses in a hemodialysis unit]. PMID- 6920068 TI - [Attempt at introduction of the public health nurse in a rural area]. PMID- 6920069 TI - [Specialty project in public health nursing]. PMID- 6920070 TI - [Nursing care of tetanus treated in an ICU]. PMID- 6920071 TI - [Only the patient knows what he wants]. PMID- 6920072 TI - [Health rights and needs]. PMID- 6920073 TI - [Aspiration method by water displacement]. PMID- 6920074 TI - [Thoracic injuries]. PMID- 6920075 TI - [Nursing care process of an older person]. PMID- 6920077 TI - [Medullary lesions. I]. PMID- 6920076 TI - [Postbasic education as development of the nurse]. PMID- 6920078 TI - [When social security is a limitation]. PMID- 6920080 TI - [Play activities in the pediatric hospital. Interview by C. Eseverri Chaverri]. PMID- 6920079 TI - [Health survey of the district of Rejas, Madrid]. PMID- 6920081 TI - Special report: how corporate hospital chains have blossomed... PMID- 6920082 TI - Life threatening abdominal emergencies: is it 'acute abdomen'? PMID- 6920083 TI - Are your fringes a waste? PMID- 6920084 TI - Would you have missed these crucial clues? PMID- 6920087 TI - The fine art of giving a physical. Detailed guidelines for a thorough examination of the breast. PMID- 6920086 TI - Confessions: the evitable hell of Timothy Bray. PMID- 6920085 TI - Septicemia from an unexpected source. PMID- 6920088 TI - Getting ready for gallbladder studies. PMID- 6920089 TI - Legally speaking: a sexist judgment threatens all of nursing. PMID- 6920091 TI - Infection consult: tactics to hold microbes at bay. PMID- 6920090 TI - Sound off! Deliver us from evil. PMID- 6920093 TI - [Scrotal contusions]. PMID- 6920092 TI - [Varicocele]. PMID- 6920094 TI - [Swollen scrotum in infancy and early childhood]. PMID- 6920095 TI - [The swollen scrotum: a varied pathology]. PMID- 6920097 TI - [Hospital hygiene: fundamental and compulsive. Hygiene in operating rooms]. PMID- 6920098 TI - [Male genitalia: anatomic review]. PMID- 6920096 TI - [Gentalline]. PMID- 6920099 TI - [Hygiene and supervision of drugs]. PMID- 6920100 TI - [Education of hospital infection control personnel]. PMID- 6920101 TI - [State diploma...2 years later, a critical evaluation]. PMID- 6920102 TI - [From the family meal... to lunch at the office]. PMID- 6920104 TI - [Inflamed swollen scrotum]. PMID- 6920103 TI - [Official procedures for receiving and adopting foreign children]. PMID- 6920105 TI - [Testicular tumors]. PMID- 6920107 TI - [Let's not forget tuberculosis]. PMID- 6920106 TI - [Inguinal scrotal pathology]. PMID- 6920108 TI - [Urogenital tuberculosis]. PMID- 6920109 TI - [Tuberculin tests]. PMID- 6920110 TI - [Epidemiology and current status of tuberculosis in France]. PMID- 6920111 TI - [Treatment of tuberculosis]. PMID- 6920112 TI - [Tuberculosis. Prevention]. PMID- 6920113 TI - [Rifadin]. PMID- 6920115 TI - [Anti-tuberculosis campaign and medico-social aspects of tuberculosis]. PMID- 6920116 TI - [A process of care among others. From records to quality of care]. PMID- 6920121 TI - [Anorexia nervosa. Family approach]. PMID- 6920118 TI - [Importance and difficulties of psychiatric symptomatology]. PMID- 6920119 TI - [Case report of anorexia nervosa]. PMID- 6920114 TI - [A case of pulmonary tuberculosis in a 45-year-old woman]. PMID- 6920123 TI - [Emotional impact of electroshock and its therapeutic consequences]. PMID- 6920124 TI - [Mental deficiency in young people]. PMID- 6920120 TI - [Symptomatology in psychiatry]. PMID- 6920122 TI - [From listening to understanding, from the latent to the manifest in nurse patient relations]. PMID- 6920126 TI - [Mother and child: the child returns to his home--role of the pediatric nurse]. PMID- 6920117 TI - [Symptomatology and education of the professional nurse in the psychiatric sector]. PMID- 6920125 TI - [Prevention of psychologic disorders in early childhood in non-psychiatric facilities. Report of a PMI team]. PMID- 6920127 TI - [Early childhood: a trial in prevention and care]. PMID- 6920128 TI - [Mother and child: the pediatrician at a PMI consultation]. PMID- 6920129 TI - [Children and child care: the child and his nanny]. PMID- 6920130 TI - [Children and child care: children and nurseries]. PMID- 6920131 TI - [Comments of a psychiatrist on the relations between a pediatric-psychiatric team and schools]. PMID- 6920132 TI - [An intermediate preventive facility. C.A.R.P.E. and admission of families]. PMID- 6920133 TI - [Intensive care in early childhood: therapeutic home care services]. PMID- 6920134 TI - [Early childhood and mental health: a team project]. PMID- 6920135 TI - [Management of rape victims]. PMID- 6920138 TI - [Rape: an act with severe psychological effects]. PMID- 6920137 TI - [Rape and the law]. PMID- 6920136 TI - [Reception and management of rape victims]. PMID- 6920139 TI - [Towards a more...human hospital?]. PMID- 6920140 TI - [Brazelton's neonatal behavior scale]. PMID- 6920141 TI - [Genesis of the rapist]. PMID- 6920143 TI - [Raped and rapists. Interview of a sexologist: Dr. Gellman. Interview by M. Garard]. PMID- 6920142 TI - [Creative illusion]. PMID- 6920144 TI - [Long term care and nursing wards can remain catheter-free]. PMID- 6920146 TI - [Nurses' own involvement is a precondition. Interview by Inga Svobakke]. PMID- 6920145 TI - [Norwegian psychiatric department's patient activities from the principles of the therapeutic community: here personnel train in self-knowledge]. PMID- 6920147 TI - [Are we the cause of pseudo-urinary incontinence?]. PMID- 6920148 TI - [The 30-year-olds are affected most by occupational injuries]. PMID- 6920149 TI - [How do relatives cope with the care of patients at home?]. PMID- 6920150 TI - [This cries out for some decency from the four corners of the world]. PMID- 6920152 TI - [Admission requirements for part 1. of Denmark's college of nursing]. PMID- 6920153 TI - [Women with a surplus aid women in need. Interview by Ulla Dietl]. PMID- 6920151 TI - [Should the hospitalized child be cared for according to myths or to needs?]. PMID- 6920154 TI - [The distance from theory to practice as a mark of poor cooperation]. PMID- 6920155 TI - [Let us have clear and identical criteria for admission]. PMID- 6920156 TI - [Exhibit on hidden sugar and healthy food]. PMID- 6920158 TI - [School health cis are not only physicians]. PMID- 6920159 TI - [Primary voting can be used following Danish Nursing Council's legislation]. PMID- 6920160 TI - [There will be primary voting on agreements]. PMID- 6920157 TI - [Impressions of Japanese health care: tasks for many toward in-depth performance for everybody]. PMID- 6920161 TI - [Negotiations remain the weak point of fixed primary voting]. PMID- 6920163 TI - [To really negotiate can compromise things]. PMID- 6920164 TI - [Philosophical significance for health and nursing care research and practice]. PMID- 6920162 TI - [The question is not mistrust but influence]. PMID- 6920165 TI - [The biggest problem is the lack of will with politicians]. PMID- 6920166 TI - [Modern treatment center for the mentally deficient in crisis after crisis: a frightening picture of conditions of the mentally deficient in the 1980s]. PMID- 6920167 TI - [Continued education - a benefit for everybody]. PMID- 6920168 TI - [Should we accept that our professional domain quietly disappears?]. PMID- 6920169 TI - [Only nurses can ensure expanded educational capacity]. PMID- 6920171 TI - [Requires greater consciousness of the working environment]. PMID- 6920170 TI - [A hidden handicap can be an extra handicap]. PMID- 6920172 TI - [Agreement on 24-hour home care]. PMID- 6920173 TI - [Evaluation of concrete child examinations. Prevention in young children in Denmark. 8]. PMID- 6920174 TI - [Swabs left behind in surgical wound]. PMID- 6920175 TI - [Changes of the blood kallikrein-kinin system in patients with coronary atherosclerosis subjected to bicycle ergometric exercise test]. PMID- 6920176 TI - Bf and C2 polymorphism in Japanese patients with juvenile onset diabetes mellitus: existence of a variant Bf allele. PMID- 6920177 TI - ['Rule and divide'; the uneasy position of health care and nursing professions in the intramural health care]. PMID- 6920178 TI - [Integrated cancer centers]. PMID- 6920179 TI - [Observations after a study: of good will but broken-winged]. PMID- 6920180 TI - [Home care of the young blind and vision-impaired child. II]. PMID- 6920181 TI - [The B. I. G.: the preliminary draft legislation on professions in the individual health care]. PMID- 6920182 TI - [Effects of radiotherapy in children]. PMID- 6920183 TI - [Psychosocial care for children with cancer in the hospital and at home]. PMID- 6920185 TI - [The nurse in the Commission for Medical Ethics]. PMID- 6920184 TI - [Democratization in health care: the end is not yet in sight]. PMID- 6920186 TI - [Nutritional requirements for maintenance and growth]. PMID- 6920187 TI - [Drug-free therapeutic community]. PMID- 6920188 TI - [How does the nurse with Intermediate Professional Education work out within within the health care system?]. PMID- 6920189 TI - [Immunological advantages of human milk]. PMID- 6920190 TI - [The feasibility of human milk for sick and small newborn infants]. PMID- 6920191 TI - [Beauty culture in the care for the mentally retarded]. PMID- 6920192 TI - [Legally regulated irregularity. Labor legislation and working times in intramural care]. PMID- 6920193 TI - [Cost control and employment opportunity development in health care]. PMID- 6920195 TI - [Hyperventilation syndrome (HVS) - its treatment]. PMID- 6920194 TI - [Home care of the young blind and visually-handicapped child. I]. PMID- 6920196 TI - [Nursing on the move - a contribution for discussion]. PMID- 6920197 TI - [Collection building in a small nursing library]. PMID- 6920198 TI - Coping: foreword. PMID- 6920199 TI - The concept of coping. PMID- 6920200 TI - Exercise and coping with stress. PMID- 6920201 TI - An assessment form for determining patients' health status and coping responses. PMID- 6920203 TI - Coping behavior: a response to stress. PMID- 6920202 TI - Assessing the coping abilities of hypertensive patients. PMID- 6920204 TI - Coping with the mastectomy crisis. PMID- 6920205 TI - Coping with organizational change. PMID- 6920206 TI - Barotrauma susceptibility in hamster lungs following elastase exposure. AB - The hypothesis that reduced lung compliance increases barotrauma susceptibility was tested in isolated hamster lungs. Elastase, instilled intratracheally in some hamsters from 4 h up to 8 days prior to testing, caused a patchy distribution of acute suppurative bronchiolitis and pneumonia. Airway blockage and decreased compliance were the anticipated results. For testing, anesthetized animals were ventilated with positive end-expiratory pressure prior to opening of the chest wall; this minimum pressure was maintained throughout testing. Transpulmonary pressure and lung volume changes, determined plethysmographically, were used to calculate quasi-static (C) and dynamic compliance (Cdyn) over a 2-ml tidal volume at frequencies up to 120 breaths/min. Some lungs were exposed, airway open, to a vacuum to stimulate a rapid ascent to the surface. All lungs were eventually pressurized through the trachea to determine rupture pressure (Pr). Rupture pressure exhibited an unexpected dichotomy apparently unrelated to elastase exposure. Statistically C did not differ between the elastase-treated and nontreated animals. Compliance correlated with Pr in a well-defined group (elastase-treated, nonevacuated lungs), but compliance had no value in predicting Pr for the group as a whole. PMID- 6920207 TI - Synthesis and processing of Sindbis virus nonstructural proteins in vitro. PMID- 6920208 TI - The purpose of continuing education for nurses: growth or "big bucks?". PMID- 6920211 TI - A celebration of life. PMID- 6920210 TI - Unmasking the operating room nurse stereotype. PMID- 6920209 TI - Ethics and nursing research. PMID- 6920215 TI - A new O.R. nursing frontier: ambulatory surgery. PMID- 6920212 TI - Nurses and the legislative process. PMID- 6920214 TI - The origin, development and accomplishments of the Association of Operating Room Nurses of Richmond area, Virginia. PMID- 6920213 TI - Operating room nurses in the perioperative role. PMID- 6920216 TI - Re-establish the operating room nursing experience in the professional student nursing program. PMID- 6920218 TI - Elastase secretion by mouse peritoneal macrophages: effects of rifampin and corticosteroids. PMID- 6920217 TI - Implementing reminiscent discussion groups. PMID- 6920220 TI - Herpes: facts and fallacies. PMID- 6920219 TI - Methicillin-resistant Staphylococcus aureus: experience in a general hospital over four years. AB - From 1977 to 1981, 317 patients in a large general hospital became infected with methicillin- and gentamicin-resistant Staphylococcus aureus. The epidemic strain was characterized as bacteriophage type D11/83A/85, resistant to methicillin, cephalosporins and aminoglycosides, and contained a 24 megadalton plasmid which mediated gentamicin resistance. Spread within the hospital followed introduction of this organism into the general surgical and burn services and resulted from cross infection between patients. These services remained a reservoir of infection throughout the four-year period. Only 2% of hospital personnel carried methicillin-resistant S. aureus in their anterior nares, and only one of them was shown to be a long-term carrier. During the epidemic, there was no overall increase in serious staphylococcal infections, as reflected in bacteremias. As methicillin-resistant S. aureus increased, there was a reciprocal decrease in methicillin-sensitive S. aureus. Later, as methicillin-resistant S. aureus bacteremias decreased, methicillin-sensitive S. aureus bacteremias increased. Attempts to control the spread of the organism by containing infected patients on an isolation ward, or by placing all such infected patients in strict isolation, decreased the frequency of infections, but did not eliminate the organism. In 1980, the burn service was separated from the surgical service and moved into a new burn unit. Also, the five-bed rooms in the hospital were being converted to two-bed rooms. With only routine isolation precautions, the epidemic resolved over the next year, although the epidemic strain persists in the hospital. PMID- 6920222 TI - Time to say good-bye. PMID- 6920221 TI - Caring for the hospitalized elderly. PMID- 6920224 TI - Noncompliance: an unacceptable diagnosis? PMID- 6920223 TI - Sleep disorders. PMID- 6920225 TI - Programmed instruction: nursing care of patients in shock. Part 1: pharmacotherapy. PMID- 6920226 TI - Shock Drugs: standardized guidelines. PMID- 6920228 TI - Nurses need to be more visible. PMID- 6920227 TI - The legal side: a matter of judgement. PMID- 6920229 TI - Death and I. PMID- 6920231 TI - Non-nursing functions. The nurses state their case. PMID- 6920230 TI - Facial fractures. PMID- 6920232 TI - Non-nursing functions. A new administration responds. PMID- 6920233 TI - Climacteric. PMID- 6920234 TI - Questions and answers about the menopause. PMID- 6920235 TI - Politics: a very human matter. PMID- 6920237 TI - Planning a self-care unit in an inpatient setting. PMID- 6920238 TI - For the nurse writer's bookshelf. PMID- 6920239 TI - Dilemmas in practice. Keeping a promise. PMID- 6920236 TI - Was this suicide preventable? PMID- 6920240 TI - [Participation of the blood kallikrein-kinin system in the pathogenesis of late pregnancy toxicosis]. PMID- 6920241 TI - Questions & answers: sunset laws and nursing. PMID- 6920243 TI - Standards for organized nursing services. PMID- 6920242 TI - Nursing practice in the care of the dying. PMID- 6920244 TI - Cardiopulmonary bypass and complement activation. Involvement of classical and alternative pathways. AB - Complement is activated during cardiopulmonary bypass with consumption of the complement components C3, C4 and factor B. This takes place when either a bubble or membrane oxygenator is used and is not affected by steroid therapy. Complement activation is predominantly by the classical pathway and may be related to the aggregation of IgM found in bypass sera. PMID- 6920245 TI - A microcell for the temperature-jump technique. PMID- 6920247 TI - Kallikrein and prekallikrein determination in a number of pathological conditions using the Centrifichem analyzer. AB - An improved method for the determination of kallikrein (K) and prekallikrein (PK) is described. The chromogenic substrate N-Benzoyl-L-Prolyl-L-Phenylalanyl-L Arginyl-p-Nitroanilidhydrochlorid is used and adapted for routine determinations with the Centrifichem 500 analyzer. A group of 30 healthy persons are compared with 10 allergic patients, three patients with hereditary angioneurotic edema and three patients with migraine attacks and the normal and pathological values described and discussed. PMID- 6920246 TI - Ultrastructural observations on morphogenesis of atypical cilia. AB - Though ultrastructural studies of bronchial epithelium both in man and in experimental animals revealed in a variety of conditions the presence of pathologically altered cilia, little is known about their genesis and significance. In this work we have described the alterations noticed in ciliary morphology during the formation of atypical cilia. A probable mechanism for their production is also proposed on the basis of our results. PMID- 6920249 TI - Clinical use of odds ratios in selecting antimicrobial therapy for bovine Pasteurella pneumonia. PMID- 6920248 TI - The role of pressure damage in pathogenesis of the downer cow syndrome. AB - Experimental downer cows were produced by maintaining healthy cows in sternal recumbency for 6, 9, or 12 hours with the right pelvic limb positioned under the body. Halothane anesthesia was used to create this artificial parturient paresis like position. In 8 of 16 experiments, cows were able to stand within 3 hours after anesthesia, but the others remained recumbent until death or euthanasia. There was no correlation between duration of the treatment and ability to stand after enforced recumbency. The appearance of the right pelvic limb of downer cows resembled the injured limbs of human patients with compartmental/crush syndrome, as well as the limbs of clinical downer cows. The affected limbs were swollen and held in rigid extension. Some animals which were able to stand also had swollen right pelvic limbs. Systemic signs of crush syndrome included dark yellow or brown urine suggestive of myoglobinuria, and marked elevation of serum creatine kinase enzyme levels. Highest creatine kinase levels were observed at 24 hours in the ambulatory group and at 48 hours in the downer group. Necropsy of downer animals revealed ischemic necrosis of the caudal thigh muscles and inflammation of the sciatic nerve caudal to the proximal end of the femur. Evidence of peroneal nerve damage was observed in at least 9 animals. PMID- 6920250 TI - Evidence for in vivo internalization of human leukocyte elastase by alveolar macrophages. AB - Cell lysates from cultured human alveolar macrophages contain detectable amounts of an elastinolytic enzyme. Although particulate elastin was solubilized only after prolonged incubations, lysates readily hydrolyzed T-OC-alanyl-p-nitrophenol ester. Hydrolysis of the latter substrate was inhibited by the leukocyte elastase site-specific inhibitor, N-ac-(ala)4-chloromethyl ketone. In addition, radioimmunoelectrophoresis of concentrated alveolar macrophage lysates, previously incubated with 3H diisopropyl-phosphofluoridate (DFP), revealed the presence of DFP binding material that comigrated with inactivated human leukocyte elastase. Human leukocyte elastase can cause lung lesions resembling pulmonary emphysema in experimental animals; therefore, the clearance of this enzyme by alveolar macrophages may represent a significant route for the removal of this potentially pathogenic enzyme from the lung. PMID- 6920251 TI - Effect of chloromethyl ketone on the progression of elastase-induced emphysema in hamsters. AB - Intratracheal administration of an elastase inhibitor (Succinyl alanyl alanyl prolyl valine chloromethyl ketone) into hamsters 20 days after induction of emphysema by porcine pancreatic elastase did not affect the lesion seen at 120 days. This study suggests that the progressive increase in lung volume between 20 and 120 days after emphysema induction was not due to a residue of active elastase in the lungs. PMID- 6920252 TI - Experimental hyaline membrane disease in the premature monkey: effects of antenatal dexamethasone. AB - A blind, randomized trial of antenatal glucocorticoid treatment was conducted using the premature monkey (Macaca nemestrina) model of hyaline membrane disease (HMD). Twelve dams received dexamethasone (2 mg/dose) 72, 48, and 24 h before abdominal delivery at 135 +/- 1 days of gestation. Twelve control animals received saline. Infants of dexamethasone-treated dams had significantly lower incidence and severity of HMD than did infants of control animals (50 versus 92%, p less than 0.05). Improvement with treatment was markedly greater for males than for females. Differences in volume-pressure behavior of the excised lungs included greater distensibility in the infants from dexamethasone-treated dams (20.6 +/- 7.1 ml/g dry lung versus 14.7 +/- 6.1, p less than 0.05) and enhanced deflation stability with treatment. Accelerated production of surface active material (SAM) phospholipids in infants from dexamethasone-treated dams was indicated by increases in total lung phospholipid (84.5 +/- 8.1 mg/g dry lung versus 75.1 +/- 9.9, p less than 0.025), alveolar lavage fluid phospholipid (5.65 +/- 3.33 mg/g dry lung versus 3.01 +/- 1.84, p less than 0.05), and alveolar lavage fluid disaturated phosphatidylcholine (DPC) (2.47 +/- 1.84 mg/g dry lung versus 1.06 +/- 1.05, p less than 0.05). Incorporation of 14C-palmitate into lung lipid was not influenced by dexamethasone, but a significantly greater portion of the label appeared in the DPC fraction with treatment. Antenatal dexamethasone treatment was successful in reducing the incidence and severity of experimental HMD in this animal model; the beneficial effects of treatment were associated with accelerated maturation of fetal pulmonary functions, including, but not limited to, synthetic metabolism of SAM phospholipid. PMID- 6920253 TI - [Abdominal CT: role of a gas reducing drug (author's transl)]. PMID- 6920254 TI - Are you satisfied with your image as an OR nurse? PMID- 6920255 TI - Nursing groups fail to form credentialing center coalition. PMID- 6920256 TI - Choosing the role in staff development that's best for you. PMID- 6920257 TI - A workable plan for OR quality assurance. PMID- 6920258 TI - Standards of administrative nursing practice: OR. PMID- 6920259 TI - A teaching plan for surgical skin preparation. PMID- 6920260 TI - Nurse-midwives attract well-informed patients. PMID- 6920261 TI - Cloned cells may be new cancer weapon. PMID- 6920262 TI - Purification of Euglena EF-1l: a cytoplasmic factor that also functions on procaryotic and organellar ribosomes. PMID- 6920263 TI - Pharmacological effects of several drugs on the myoepithelium and the vascular smooth muscle of the lactating mammary gland in goats. AB - The present experiments were performed to investigate whether the responses of the myoepithelium to several drugs would be of a parallel nature with those of the vascular smooth muscle in the lactating mammary gland of goats. The drugs were injected into the mammary artery. Kallikrein, bradykinin, oxytocin, and acetylcholine caused marked milk-ejection with vasodilation in a dose-dependent manner. Marked milk-ejections with high doses of oxytocin were observed despite of accompanying vasoconstriction. The relative order of their potency in milk ejection activity was kallikrein greater than bradykinin greater than oxytocin greater than acetylcholine: 1 greater than 1/100 greater than 3/1000 greater than 5/1000000. As for the vasodilator activity, the relative potency of the drugs was in the same order: 1 greater than 1/10 greater than 1/1000 greater than 1/10000. Catecholamines, histamine, serotonin, angiotensin-II, vasopressin and high doses of prostaglandin E2 caused dose-dependent vasoconstriction. Isoprenaline, pilocarpine, adenosine, PGI2 and low doses of PGE2 caused dose-dependent vasodilation. But these drugs did not affect milk-ejection. PGE1 decreased milk ejection and was accompanied by vasodilation. From these experiments it is suggested that the relative order of the potency of secretagogues in milk ejection activity and in vasodilator activity is nearly equal. It is also suggested that some drugs are different in their effects on the myoepithelium and on the vascular smooth muscle of the lactating mammary gland. PMID- 6920264 TI - The nurse and the law: mail bag. PMID- 6920265 TI - Myelomeningocele--the spina bifida effect. PMID- 6920267 TI - Aboriginal health workers compare notes in New Guinea. PMID- 6920266 TI - Nursing--industry or profession? PMID- 6920268 TI - A college-based basic nurse course in summary. PMID- 6920269 TI - Continuing the nursing fiasco. PMID- 6920271 TI - The implications for nursing of the sex discrimination act 1975. PMID- 6920270 TI - Genetic counselling. PMID- 6920272 TI - Ascorbate--the proof of the pudding! A selection of case histories responding to ascorbate. PMID- 6920274 TI - Electrical burns. PMID- 6920273 TI - The place of amniotic membrane in the treatment of burns in children. PMID- 6920276 TI - 'Man and disease'--a brief look at one hundred and twenty years of opinion. PMID- 6920275 TI - The psychological effects on nursing staff working in a burns unit. PMID- 6920277 TI - Birth centres. PMID- 6920278 TI - Elastin degradation by proteases from cultured human breast cancer cells. PMID- 6920279 TI - Presence of the pre-mRNA for the 72k DNA binding protein in hnRNP from early adenovirus-2 infected HeLa cells. PMID- 6920280 TI - The structure of aspartate transfer RNA from rabbit liver. PMID- 6920281 TI - Modification of neuroblastoma x glioma hybrid NG108-15 adenylate cyclase by vanadium ions. PMID- 6920282 TI - Action of ammonium meta vanadate on the activities of hepatic drug-metabolizing enzymes in vitro. PMID- 6920283 TI - Catalytic properties of human urinary kallikrein. AB - Kinetic studies have been carried out with a well-characterized preparation of human urinary (h.u.) kallikrein using chromogenic substrates. Steady-state and pre-steady-state data for h.u. kallikrein catalyzed hydrolysis of N alpha carbobenzoxy-L-lysine p-nitrophenyl ester (ZLysONp) and of N alpha-carbobenzoxy-L alanine p-nitrophenyl ester (ZAlaONp) in the presence and absence of ethylamine and acetamidine have been obtained under various conditions and have been analyzed in the framework of the minimum three-step mechanism: (formula see text) The pH dependencies of the kinetic parameters for the hydrolysis of ZLysONp and ZAlaONp in the presence of saturating levels of ethylamine and acetamidine show that at acid pH values (less than or equal to 4) the k3 step (deacylation) is rate limiting in catalysis, whereas for pH values greater than or equal to 6, k2 (acylation) becomes rate limiting. On the other hand, the acylation step is rate limiting in the enzymatic hydrolysis of ZAlaONp over the whole pH range explored. Saturating concentrations of acetamidine increase, more than those of ethylamine, kcat for the hydrolysis of ZAlaONp. The affinity of h.u. kallikrein for acetamidine and ethylamine changes about 5-fold with pH between pH 5 and 3. The pH dependence of the spectral properties of free hu. kallikrein reflects the ionization of a group with a pKa value of 4.45 +/- 0.1. The results point out that, similarly to bovine beta-trypsin, h.u. kallikrein catalysis involves an ionizable group which has a pKa of about 4.5 in the free enzyme and a pKa of about 3.7 in the enzyme bound to cationic substrates or ligands. PMID- 6920285 TI - Failure of rifampin to eradicate methicillin-resistant Staphylococcus aureus colonization. AB - Four patients with methicillin-resistant Staphylococcus aureus (MRSA) carriage in one body site each (urine, anterior nares, throat, or wound) received 300 mg of oral rifampin twice daily for ten days. Treatment did not eradicate MRSA carriage in any patient, and three of the posttherapy isolates were highly resistant to the drug. Rifampin by itself does not appear to be an effective drug for the eradication of MRSA carriage. PMID- 6920284 TI - Formation of ether lipids and wax esters in mammalian cells. Specificity of enzymes with regard to carbon chains of substrates. AB - The incorporation of radioactivity from individual constituents of an equimolar mixture of saturated straight-chain alcohols (14:0, 16:0, 18:0, 20:0) and of nearly uniform mixtures of isomeric cis- or trans-octadecenols (delta 8-delta 16) into alkyl, alk-1-enyl and acyl moieties of diradylglycerophosphocholines and diradylglycerophosphoethanolamines and into alkyl and acyl moieties of wax esters was studied in rat brain as well as in L 1210 and S 180 ascites cells. The pattern of incorporation of radioactivity from the substrates into alkyl and alk 1-enyl moieties of ether phospholipids and into alkyl moieties of wax esters reveals the following: (1) The enzymes catalyzing the biosynthesis of alkylacylglycerols, the common intermediates of cholinephospholipids and ethanolaminephospholipids, have no substrate specificity with regard to position of the double bond of either cis- or trans-octadecenols or of intermediate ether lipids derived therefrom. (2) CDPcholine:diradylglycerol cholinephosphotransferases exhibit a strong preference for alkylacylglycerols with cis-8, cis-9 and cis-10-octadecenyl moieties, but no preference for the double bond position in the trans-octadecenylacylglycerols. (3) CDPethanolamine:diredylglycerol ethanolaminephosphotransferases have no substrate specificity with regard to position of the double bond in cis- or trans octadecenyl moieties of alkylacylglycerols. (4) THe enzyme systems catalyzing the biosynthesis of alkylacylglycerophosphocholines and alkylacylglycerophosphoethanolamines exhibit substrate specificity with regard to chain-length of saturated alcohols and intermediate ether lipids derived therefrom. (5) Alkylacylglycerophosphoethanolamine desaturase and (6) wax ester synthase are highly specific for alkylacylglycerophosphoethanolamines and long chain alcohols, respectively, with regard to chain-length of saturated alkyl moieties, but not with regard to position of double bonds of cis- or trans octadecenyl moieties. PMID- 6920288 TI - [On nursing and education (9) - current status and problems of practical nursing education (1)]. PMID- 6920287 TI - [In search of a starting point in nursing education - an encounter with nursing theories in the past 10 years]. PMID- 6920286 TI - Basic study on the fluorometric determination of elastase activity. PMID- 6920289 TI - [Understanding of the "Process for Nursing Planning" by Louis Power (3) - A totalistic approach in nursing and nursing models]. PMID- 6920291 TI - [On "analysis of a nursing process for a patient with impulsive sexual behavior"]. PMID- 6920290 TI - [Scientific accountability in nursing]. PMID- 6920292 TI - [On the "analysis of a nursing process for a patient with impulsive sexual behavior": a discussion]. PMID- 6920294 TI - [The role of women and nursing - a lesson in folk medicine. 3]. PMID- 6920293 TI - [Analysis of a nursing process for a patient with impulsive sexual behavior]. PMID- 6920295 TI - Fences (school nursing). PMID- 6920297 TI - Increased renal kallikrein excretion in SIADH after vincristine therapy. AB - This is a report about a 14-year old girl who, following chemotherapy for malignant teratoma, developed a clinical state of SIADH (syndrome of inappropriate secretion of antidiuretic hormone). The causative agent was most likely vincristine (VCR). The important feature in this case was that the urinary kallikrein activity was high when she was affected by SIADH and decreased when her hyponatremia improved. Sodium clearance was significantly correlated with the increase in urinary kallikrein activity. It is considered that the kallikrein kinin system may in part participate in the excessive natriuresis of SIADH. PMID- 6920296 TI - In vitro activity of BU-2313B against anaerobic bacteria. AB - The antimicrobial efficacy of BU-2313B, a new antibiotic, was evaluated in comparison with clindamycin, chloramphenicol and cefoxitin against 265 clinical anaerobic isolates. BU-2313B inhibited 88% of 66 isolates of Bacteroides fragilis tested at 2 micrograms/ml, whereas clindamycin, chloramphenicol and cefoxitin inhibited 98, 97 and 92% of them at 2, 8 and 16 micrograms/ml, respectively. BU 2313B was severalfold more effective than chloramphenicol and cefoxitin, but it was eight times less effective than clindamycin. PMID- 6920298 TI - Complement factors and acute phase reactants in the Guillain-Barre syndrome. AB - The concentrations of C3, C4, C1 inactivator, C3 proactivator and orosomucoid were determined in sera from 13 patients with Guillain-Barre syndrome. The most severely affected patients had the highest levels of C3, C4 and orosomucoid in the acute phase with a slight decline over the following 3-8 weeks. The mildly affected patients had complement concentrations in the upper normal range. In the group of patients with the highest concentrations of C3, C4 and orosomucoid, 4 out of 6 developed residual weakness, while residual weakness was only found in 1 out of 7 with normal concentrations. The measurement of C3 and C4 may, therefore, be of value in estimating the severity and prognosis in the early phase of the disease. PMID- 6920300 TI - [Vaccine prophylaxis of measles]. PMID- 6920301 TI - [Concern for schoolchildren's sight]. PMID- 6920299 TI - Inhibition of alternative pathway factor D by factor B-related synthetic hexapeptides. AB - Hexapeptides mimicking the partial amino acid sequence of factor B surrounding the bond that is cleaved by factor D have been synthesized. These peptides have been assessed for their ability to inhibit factor D enzymatic activity and for their susceptibility to serine proteases. The synthetic peptides were cleaved by bovine trypsin and C1s but not by alpha-thrombin and factor D. The peptides inhibited factor B cleavage and fluid-phase or cell-bound alternative pathway C3 convertase activation by factor D. Altogether, these results suggest that peptides analogous to factor B specifically inhibit factor D enzymatic activity. Thus, they constitute an interesting tool for study of alternative pathway activation and can be of use when attempting to manipulate this pathway, since factor D is an essential component for alternative pathway initiation and amplification. PMID- 6920302 TI - [Myopia in children, its treatment and prevention]. PMID- 6920303 TI - [Use of contact lenses]. PMID- 6920304 TI - [Prevention and treatment of strabismus]. PMID- 6920305 TI - [Early diagnosis and treatment of congenital eye diseases in children]. PMID- 6920307 TI - [Early diagnosis and effective treatment of acute conjunctivitis in children]. PMID- 6920308 TI - [Current problems of child and adolescent health protection]. PMID- 6920309 TI - [Detection and treatment problems of eye tumors in children]. PMID- 6920310 TI - [Diagnosis and the principles of treating inflammations of the vascular coat of the eye in children]. PMID- 6920311 TI - [Clinical aspects, early diagnosis and prevention of retinal detachment]. PMID- 6920306 TI - [Dacryocystitis in the newborn]. PMID- 6920313 TI - [Closed and open abdominal injuries]. PMID- 6920312 TI - [Prevention of pediatric eye injuries and emergency ambulatory care]. PMID- 6920314 TI - [Blood reinfusion in acute blood loss]. PMID- 6920315 TI - [Spinal osteomyelitis]. PMID- 6920317 TI - [Functional diagnostic methods in cardiovascular diseases]. PMID- 6920316 TI - [Morgagni-Adams-Stokes syndrome]. PMID- 6920318 TI - Using research in practice. Can (cardiac) patients be taught effectively in the critical care setting? PMID- 6920320 TI - Professional communications. How to prepare a lecture presentation. PMID- 6920319 TI - Shared goals help unite critical care nurses. PMID- 6920322 TI - Benefits of belonging to a national organization, part II. PMID- 6920324 TI - Selecting critical care monitoring equipment. PMID- 6920323 TI - NWCAC's Public Affairs Committee--a chronological development. PMID- 6920325 TI - A.R.N.P on the run. PMID- 6920321 TI - The environmental health challenge of the 80's. PMID- 6920326 TI - "Does it make a difference ?". PMID- 6920327 TI - [Estimates of the cost of the introduction of colposcopy into the screening for cervical carcinoma (author's transl)]. PMID- 6920329 TI - [Exclusive external irradiation of advanced cancers of the cervix uteri (author's transl)]. PMID- 6920328 TI - [Occurrence and histological structure of adenocarcinoma of the endocervix after long-term use of oral contraceptives (author's transl)]. PMID- 6920330 TI - [Induction of malignant tumours in the pelvic region by radiotherapy of gynaecological diseases (author's transl)]. PMID- 6920331 TI - [Treatment of Motor urge incontinence with Clenbuterol (author's transl)]. PMID- 6920332 TI - [Metronidazole prophylaxis for vaginal hysterectomy (author's transl)]. PMID- 6920334 TI - [The determination of the rubella titre during antenatal care-possibilities of the surveillance of a preventive program by a central serological laboratory (author's transl)]. AB - The material sent to the state serological laboratory Braunschweig for the determination of the rubella titre during antenatal care was found to come from pregnant women who are older than the average age of primi-gravidas in lower saxony. A re-check of the maternity care booklets showed that some rubella titre determinations were done after the first pregnancy. The rubella titre was determined during the present pregnancy earlier in accordance with the early presentation of patients for antenatal care. This followed the unusual well known patterns. Proposals are made for the continued evaluation of the antenatal care program with simple methods. PMID- 6920333 TI - [Late complications after application of different sterilization techniques -- a comparison between the monopolar HF-sterilization and the endocoagulation method (author's transl)]. PMID- 6920337 TI - [Observation of newborn, Contribution to the "sudden infant death syndrome" (SIDS) (author's transl)]. AB - The occurrence of sudden child death in the Gynaecological Department of the Free University has led to the development of special monitors, on which all the children can be observed while their mothers are in the maternity ward. Our findings show that apnoeic intervals occur among newborn children more frequently than is generally assumed. Whether, and to what extent attacks of apnoe can lead to sudden child death can not be determined from our own statistics. In the literature, which is cited individually, a direct correlation is described by very many authors. Almost all of them agree that through continuous monitoring of breathing it is often possible to register risk situations for newborns before a real disease becomes manifest. Our experience justifies the demand that every child's respiration be monitored, especially in clinics which handle a large number of risk pregnancies and births. PMID- 6920336 TI - [Tocolysis in emergency cerclage (own technical procedure, prognosis) (author's transl)]. PMID- 6920335 TI - [The cardiac hazard of tocolysis and antagonising possibilities. I. The haemodynamic situation of the patient during tocolysis/Protection of the myocardium by means of cardioselective beta-blockade. Experimental results (author's transl)]. AB - 7 mongrel dogs underwent general anaesthesia and thoracotomy. For the assessment of the haemodynamic situation the following parameters were measured: Left ventricular and aortic pressure, coronary flow, oxygen-saturation in the coronary sinus, pulmonal arterial pressure, central venous pressure, heart rate. From these measurements cardiac output volume and myocardial oxygen consumption could be calculated. Using an ultrasound transit-time method regional myocardial function could be assessed. After the establishment of these measurements Fenoterol has been given in an increasing dosage up to the upper therapeutical range. Then additionally the cardioselective beta-antagonist Metoprolol was administered stepwise up to a total dose of 1.2 mg/kg body weight. The measurements proved evidence, that a relatively small dose of 0,2-0,4 mg Metoprolol/kg body weight is sufficient to compensate the haemodynamic situation impaired by Fenoterol, esp. the rise in myocardial oxygen consumption. PMID- 6920338 TI - [The ultra-sound diagnosis of Meckel-syndrome (author's transl)]. AB - A case is reported of an antenatal completely sonographic diagnosis of a case of Meckel-Syndrome. During the second ultra-sound screening at 33 weeks gestation the suspicion of hydrocephalus was diagnosed. An extended ultra-sound diagnosis at 34 gestation showed the following: 1. internal hydrocephalus 2. encephalocele or meningomyelocele 3. bilateral polycystic kidneys 4. suspicious of aplasia of the diaphragm on the left 5. suspicious of hepatic cysts. The infant died a few hours after delivery. The autopsy report corroborated the essential features of the ultra-sound diagnosis. In summary these were interpreted as meckel-syndrome. This case shows that a complete antenatal diagnosis of meckel-syndrome by ultra sound only is possible. The case also shows that diagnosis prior to 24 weeks gestation is desirable in order to carry out the necessary treatment. PMID- 6920340 TI - [Pregnancy following Addison-Crisis (author's transl)]. PMID- 6920341 TI - [Caesarean section in a dead women (author's transl)]. AB - A case of Caesarean section on a deceased pregnant woman is described. Medical Ethics dictates to carry out this operation as long as their is hope for the delivery of a live infant. A review of the literature suggests to proceed in the following manner: When the mother is with certainty clinically dead and a still viable infant is expected the physician has to proceed with a classical Caesarean section immediately. No preparation is carried out. One scalpel is all that is needed for the operation. Resuscitation methods in the clinically dead mother have to be continued until the infant has been delivered. PMID- 6920339 TI - [Ultrasonic diagnosis of haematocolpos (author's transl)]. PMID- 6920342 TI - [Artificial vagina through lyodura (dura mater cerebri) (author's transl)]. PMID- 6920343 TI - [Vaginism - a surgical or consultative problem? (author's transl)]. AB - For the last one hundred years or so doctors have been confronted with the phenomenon of vaginism as a functional sexual disturbance. 70 years ago the psychogenetic nature of this disturbance was recognized, and yet gynaecologists and surgeons are still suggesting and practising surgical and mechanical interventions at the vaginal orifice. This is indeed regrettable - and not only because such attempts remain unsuccessful: in this manner doctors are fixed on the idea of an organic cause of the disturbance instead of motivating the patients to undergo consultative treatment. Vaginism may even entail psychosocial advantages for the women in some cases. PMID- 6920344 TI - [Congenital bilateral amastia in a mother and a daughter (author's transl)]. AB - A 23 year-old primigravida with bilateral congenital amastia was delivered at 38 weeks gestation following early rupture of the membranes. The mature newborn female also showed congenital bilateral amastia. In addition mother and daughter showed a mild hook finger of both 5th fingers. The mother only had 19 permanent teeth. About the permanent in the infant no data were obtained. This type of manifestation of a congenital anhydrotic ectodermal dysplasia is probably due to a sex-linked recessive gene. Newer investigations in experimental embryology show that the complete inhibition of the growth of the ectodermal milkridge occurs in the 6-12 th week of intra-uterine life and may also occur as an embryopathy due to dehydroepiandrosterone. PMID- 6920345 TI - "Editorial creates spurious issues"? A home is not a hospital. PMID- 6920346 TI - Nutrition: helping seniors shop for food. PMID- 6920347 TI - You can go home again. PMID- 6920348 TI - Territory and privacy: residents' views : findings of a survey. PMID- 6920350 TI - Staking a claim: steps patients take to establish their own territory, and how nurses can help them. PMID- 6920349 TI - Intervention vs. interference. PMID- 6920352 TI - My friend David: our need for tenderness and affection does not diminish with age. PMID- 6920351 TI - Washable pads or disposable diapers? PMID- 6920353 TI - The hospitalized elderly--a first look. PMID- 6920354 TI - Observations of eldercare in the USSR. PMID- 6920355 TI - Physical fitness on a VA nursing home unit. PMID- 6920356 TI - Common concern: sex and aging--a game people play. PMID- 6920358 TI - [Relationship among urine, urinary electrolyte excretions, renin aldosterone- and kallikrein-system in healthy young Japanese and American women--analysis of circadian rhythm by Cosinor method and correlation of acrophase and amplitude in circadian rhythm among the variables (author's transl)]. PMID- 6920357 TI - 70+ and going strong: Ginny with the black feet. PMID- 6920359 TI - Characterization of the CNBr peptides generated from the factor B cleavage fragments, Ba and Bb, by molecular exclusion high performance liquid chromatography. AB - Highly purified human factor B of the alternative complement pathway was treated with factor D in the presence of cobra venom factor to generate its Ba and Bb cleavage fragments. These cleavage fragments were isolated by preparative polyacrylamide gradient gel electrophoresis followed by electrodialysis elution and treatment with CNBr. The resultant CNBr cleavage peptides were isolated by molecular exclusion high performance liquid chromatography and characterized by SDS polyacrylamide gel electrophoresis. Results of these experiments indicate that the Ba fragment essentially consisted of a 28,000 CNBr peptide, whereas 34,700 (28,000 + 3,500 when characterized under reducing polyacrylamide gel electrophoresis conditions); 14,500 (=20,000); and 8,300 CNBr peptides were derived from the Bb fragment. PMID- 6920361 TI - Studies of chronic bronchitis show impact of antibiotic selection. PMID- 6920360 TI - Prophylactic antibiotics for pediatric surgery. PMID- 6920363 TI - Pitfalls in the application of multivariate regression. PMID- 6920362 TI - Clinical and laboratory studies of nosocomial Staphylococcus aureus resistant to methicillin and aminoglycosides. AB - A methicillin/aminoglycoside-resistant strain of Staphylococcus aureus (MARS) was likely introduced by transfer of a patient from another hospital. Over the next year, 20 other patients were colonized or infected with MARS of the same phage type, although antibiograms varied. Affected patients usually had serious underlying disease and were in intensive care units. Vancomycin therapy was frequently delayed and MARS may have contributed to the death of some patients. The mode of spread was not definitively delineated, but two nurses were found to be colonized. Institution of isolation procedures was difficult, but the problem gradually waned. Susceptibility testing showed vancomycin to be the most active agent. Synergy studies showed no consistent effect of combining methicillin with an aminoglycoside. This experience illustrates the problem of MARS spread between hospitals and wards, the need for institution of effective control measures, and consideration of early empiric use of vancomycin. PMID- 6920365 TI - Does health visitors' training equip them to meet clients' needs? PMID- 6920364 TI - Responsibility for the future development of health visiting. PMID- 6920366 TI - A preventive approach to family life - the role of the health visitor. PMID- 6920368 TI - Health visitors as other professionals see them. PMID- 6920367 TI - Personality variables and personality testing in health visitor selection. PMID- 6920369 TI - Improving the image. PMID- 6920370 TI - A consumer view of the health visiting service. PMID- 6920371 TI - A consumer view of the health visitor at six weeks postpartum. PMID- 6920372 TI - Making a health profile of an area. PMID- 6920373 TI - The gas man cometh. PMID- 6920374 TI - Health Visitors' Association training group. Health visiting and neighbourhood studies: a discussion document. PMID- 6920375 TI - From the grass roots. PMID- 6920376 TI - Increase in content and release of kallikreinogen in acute experimental pancreatitis in rats. PMID- 6920378 TI - ["Primeiro de Maio" health center in Mozambique]. PMID- 6920377 TI - [Preventive dental care for prospective mothers]. PMID- 6920379 TI - [How to stick the heel of newborn infants]. PMID- 6920380 TI - [Parent education and psychoprophylaxis - how can they go together?]. PMID- 6920381 TI - [Study trip to Paris]. PMID- 6920382 TI - [Newborn infants--bathing or washing? A pilot study performed as a topic in research and statistics]. PMID- 6920383 TI - [Maternity care in Zambia]. PMID- 6920384 TI - The tetracyclines in purulent exacerbations of chronic bronchitis. PMID- 6920385 TI - Chicken antithrombin. Isolation, characterization, and comparison with mammalian antithrombins and chicken ovalbumin. AB - Chicken antithrombin was purified from fresh chicken plasma by affinity chromatography using heparin-agarose, and its amino acid and carbohydrate compositions, amino-terminal sequence, inhibition of human thrombin, and immunological properties were studied and compared with previously studied mammalian antithrombins (human, pig, rabbit, and rat), and also with chick ovalbumin. Chicken antithrombin is a single-chain glycoprotein with a total carbohydrate content of 17.5%, including 6.0% N-acetylglucosamine, 8.7% hexose, and 2.8% N-acetylneuraminic acid. The molecular weight estimated from sodium dodecyl sulfate(SDS)-polyacrylamide gel electrophoresis was 60,000. The amino terminal sequence has been determined as Ala-Pro-Tyr-Ala-Val-Glu-Asp-Ile-Cys-Thr Ala-Lys-Pro-Thr-Asp-Ile-Pro-Val-Asn, which is highly homologous to the terminal sequences of mammalian antithrombins, although the first 4 residues are quite different from those of mammalian species. Chicken antithrombin showed a stoichiometric inhibition against thrombin. The apparent dissociation constant (K1) for the complex was 6.4 X 10(-8) M. No immunological cross-reactivity was observed between chicken and mammalian antithrombins. Ovalbumin, which Hunt and Dayhoff (Biochem. Biophys. Res. Commun. 95, 864-871, 1980) proposed should be grouped in the same superfamily as antithrombin, showed neither immunological cross-reactivity with antithrombin or with its carboxymethylated derivative, nor any effect on the thrombin-antithrombin interaction. Ovalbumin showed no inhibitory effect on porcine elastase, either. PMID- 6920386 TI - The nucleotide sequence and codon recognition of proline tRNA from Torulopsis utilis. AB - Proline tRNA from Torulopsis (Candida) utilis was purified by chromatography on columns of DEAE-Sephadex A-50 at pH 7.6 and 4.0, DEAE-Sephadex A-50 at pH 6.0, and RPC-5 at pH 4.0. This tRNA was sequenced by combining conventional chromatographic methods with rapid read-out chemical and enzymatic gel sequencing methods. The tRNA consists of 75 nucleotides and had the following sequence: pG-G C-Cm-G-C-G-U-m1G-G-U-C-psi-A-G-D-G-G-D-A-U-G-A-U-A-C-U-C-G-C-U-U-N-G-G-m1G -psi-G psi-G-A-G-U-G-m7G-D-m5C-m5C-A-G-G-G-T-psi-C-A-m1A-U-U-C-C-C-U-G-C-U-C-G- G-C-C-C C-C-A. An unknown nucleotide in the first position of the anticodon was shown to be an uridine derivative by UV-spectrum, mobility on thin-layer chromatogram, and preliminary measurement of NMR spectrum. The specificity of this tRNA for codon recognition was studied by the ribosomal binding technique. Three out of four proline codons were recognized: CCA and CCU preferentially, and CCC weakly. Unexpectedly, CCG failed to bind this tRNA to ribosomes. PMID- 6920387 TI - A heat-stable protein synthesis initiation factor from wheat germ. AB - A protein synthesis initiation factor of molecular weight 21,500 has been purified to homogeneity from extracts of wheat germ. The factor, referred to as D2d, is stable to heating for 5 min at 75 degrees C and loses less than 15% of its activity upon a similar treatment at 90 degrees C. In contrast, all other wheat germ protein synthesis factors are inactivated by heating for 5 min at 65 degrees C. Formation of 80 S ribosome . Met-tRNAiMet complexes from 40 S ribosome . Met-tRNAiMet complexes, as measured by the binding of [3H]Met-tRNAiMet, is almost completely dependent upon the presence of component D2d. The shift in sedimentation of the ribosome subunits to the 80 S ribosome region, however, occurs in the absence of factor D2d. Thus, the role of the factor is not to join the ribosomal subunits, but rather to keep the Met-tRNAiMet bound to the ribosome. The formation of 40 S ribosome . Met-tRNAiMet complexes is increased 2 fold by the presence of factor D2d. Fixing this complex with glutaraldehyde results in the binding of more Met-tRNAIMet than a nonfixed incubation in the presence of D2d. These results suggest that the primary interaction with the ribosomal subunit can occur in the absence of factor D2d, but that the presence of the factor stabilizes the ribosome-bound Met-tRNAiMet. PMID- 6920390 TI - Kinetic nursing--a new approach to the problems of immobilization. PMID- 6920389 TI - Management of the patient in a Halo brace. PMID- 6920391 TI - Sex and the spinal cord injured patient. PMID- 6920388 TI - Postoperative infection caused by an unusual serotype of Streptococcus pneumoniae associated with multiple drug resistance. AB - A 15-month-old child developed an infectious pulmonary complication of open heart surgery. Cultures of the respiratory secretions showed growth of a 9L serotype of Streptococcus pneumoniae which was resistant to penicillin, tetracycline, and chloramphenicol. There was no evidence that the organism was spread among the family of the patient or hospital personnel. PMID- 6920392 TI - Acute care of the high-level quadriplegic patient. AB - Four months post-injury, Mark is into the ongoing rehabilitation phase of his hospitalization. He is free of continuous ventilator support with a vital capacity of 1200 cc. Neurologically, his level has descended to the C5 level, which has allowed him to function with moderate assistance from a motorized wheelchair. He is still immobilized in a Halo vest which will be removed when X ray examination reveals that adequate fusion has occurred. Mark has not developed pulmonary embolus. After an initial problem with orthostatic hypotension, he can sit upright without symptomatology. Although he will probably continue to have difficulty with temperature regulation, Mark has learned how to control his environment in order to maintain his comfort and safety. Bowel training was difficult because of Mark's initial problem with paralytic ileus. With persistent adherence to the bowel program, however, Mark has become bowel continent. This process was facilitated once he was able to be mobilized and use a bedside commode. Mark continues on his bladder retraining program. As could be anticipated with an adolescent patient, adherence to the strict program of fluid regulation and restriction was difficult. It is anticipated that Mark will eventually be catheter-free and bladder continent in the future. Mark will require two to three months of further rehabilitation, after which he will return to his home and school. Mark faces a future centered from a wheelchair. With adequate medical, nursing, psychological, social and vocational follow-up, however, he can live a near normal life-span. With a positive support system he can build on the comprehensive care he received initially, and rebuild a life for himself. PMID- 6920393 TI - Regional spinal cord injury center nursing care: prescription for the present and the future. PMID- 6920394 TI - Patient preparation and transfer to a regional spinal cord injury center. PMID- 6920395 TI - Intra-operative assessment of the neurosurgical patient. PMID- 6920396 TI - Intra-operative aneurysm clipping. PMID- 6920397 TI - Dietary cadmium, zinc and copper: effects on chick lung morphology and elastin cross-linking. AB - Day-old White Leghorn cockerels were divided into seven dietary groups and fed one of the following diets: 1) a casein-based basal diet; 2) a casein-based diet supplemented with 10 mg/kg cadmium, 3) 100 mg/kg cadmium, 4) or 800 mg/kg zinc; 5) a casein-based diet pair-fed to the 100 mg/kg Cd group; 6) a spray-dried nonfat milk-based diet with no added copper, or 7) a spray-dried nonfat milk based diet supplemented with 5 mg/kg copper. At termination (5 weeks), the birds were killed, and the effects of the diets on selected features of lung composition and morphology were assessed. Body weights were reduced in the 100 mg/kg Cd, pair-fed, and Cu-deficient groups when compared to their controls (casein-based or milk-based copper-supplemented diets). There were no differences in lung weights (expressed relative to metabolic body size) among the groups, although copper deficiency did result in a slight decrease in the dry to wet weight ratio of lung. Lung elastin content and the desmosine content in elastin were significantly lower in the Cu-deficient group and tended to be lower in the group fed 800 ppm Zn. Significant alterations (enlargement of the tertiary bronchial lumen) in morphology were also observed in lungs from both the 100 mg/kg Cd and Cu-deficient groups. Alteration in lung morphology observed in the 100 mg/kg Cd group could not be explained by changes in the elastin content of lung. PMID- 6920398 TI - Diuretics--Part II. Potassium sparing. PMID- 6920399 TI - Skin cancer and the sun. PMID- 6920401 TI - In defense of bottle-feeding. PMID- 6920400 TI - Fetal alcohol syndrome. PMID- 6920402 TI - Team nursing reduces stress. PMID- 6920403 TI - Expanding role of the LPN. PMID- 6920404 TI - A psychiatric nursing perspective on DSM-II. PMID- 6920405 TI - Adlerian community treatment with schizophrenic clients. PMID- 6920406 TI - The use of music with autistic children. PMID- 6920407 TI - Clinical practice: intuitive or based on research? PMID- 6920408 TI - Teaching patients self care: a critical aspect of psychiatric discharge planning. AB - This article has dealt with selected issues in patient education that involves teaching patients self care in the mental health delivery system. It has presented several predischarge teaching techniques that have been used in a research study by the first author and other strategies that have been found to be effective in both authors' clinical practice. There are many other areas in need of systematic investigation related to self-care skills. The first author's study is one of very few conducted by psychiatric nurses to document effective self-care treatment techniques (Figure). We hope that other clinicians and researchers will become interested in this area and add to the knowledge base of self care in the field of psychiatric-mental health nursing. PMID- 6920409 TI - Self medication among psychiatric patients and adherence after discharge. PMID- 6920411 TI - Right brain-left brain: the nurse consultant and behavior change following stroke. AB - In summary, I have made suggestions for working with staff to promote empathy for the stroke patient presenting with behavior problems. All of us take for granted our "two ways of knowing," the richness of our experience being promoted by the two sides of our brain. When brain damage occurs, the results are sometimes dramatic as with paralysis or expressive aphasia, and sometimes subtle as with receptive aphasia and certain visual-spatial problems. Nursing staff provide the care which otherwise would have been self care. When expectations are low, patients withdraw and staff "care ... less." When expectations are high, patients become symptomatic, staff burned out. The nurse consultant can intervene most effectively by addressing the total milieu, enriching the perspective of staff and family members who are seeing only one side of the whole. PMID- 6920410 TI - Comparison of psychiatric-mental health nursing education objectives: consumers, educators, and practitioners. AB - This consumer-nurse study was part of a larger project, Research in Mental Health Education, which compared the priorities of educators and practitioners within and between three core mental health professions and between the professionals and consumers. In the consumer-nurse portion of the study, the objectives for graduate education in psychiatric-mental health nursing were validated by psychiatric-mental health nursing educators (N=20) based in four university programs in the East, West, and Midwest. Another sample of nurse educators and practitioners in this specialty area, drawn from nine states, prioritized these objectives. A separate deck of objectives for mental health professionals was generated and prioritized by consumers (N=15) who were members of the Mental Health Association of Minnesota. Standardized procedures for generating and validating the objectives for nurses and consumers and the same task, the Priority Sort, were used by all subjects, nurses, and consumers, to prioritize the objectives. Similarities and differences between nurses and consumers are discussed. Differences between nurse educators and practitioners, which are statistically significant, also are described. Implications for consumer and practitioner input into curricular decisions are discussed as well as interdisciplinary courses that could conserve faculty time and budgetary resources. PMID- 6920412 TI - Mapping urban hotels: life space of the chronic mental patient. PMID- 6920413 TI - Evidence for microwave-induced acoustical resonances in biological material. AB - Pulse bursts of microwave energy were used to stimulate resonant-type acoustical response in a rectangular muscle-equivalent model and in a spherical brain equivalent model. The rectangular model was irradiated using a military radar transmitter at 5.655 GHz, 200 kW peak, and the spherical model was irradiated using a pulse-type cavity oscillator at 1.10 GHz, 4 kW peak. Hydrophone transducers were implanted in the models to record the microwave-induced mechanical vibrations. Four properly timed radar pulses produced a threefold increase in the acoustical amplitudes in the muscle model. In the spherical model, a pulse train of three properly timed microwave pulses doubled the stress wave amplitudes as recorded by the implanted hydrophone. These results show that certain pulse parameters of microwave irradiation can be adjusted to increase the intensity of induced mechanical vibrations in both rectangular and spherical tissue equivalent models. PMID- 6920414 TI - Local hyperthermia using microwaves for therapeutic purposes - experimental studies of various applicators. PMID- 6920415 TI - Effects of 42- and 2450-MHz dielectric heating on nutrition-related properties of soybeans. AB - Dielectric heating at frequencies of 42 and 2450 MHz was applied to whole soybeans of natural moisture content for varies exposure times. The minimum energy absorbed (MEA) was calculated from moisture-loss and temperature-elevation data. Biochemical analyses were performed to determine protein dispersibility index (PDI), nitrogen solubility index (NSI), and trypsin-inhibitor, urease, lipoxygenase, and peroxidase activities. Because the heating rates were different at the two frequencies for the power levels used, plots of the biochemical properties against temperature of exposure time showed an apparent frequency dependence. This dependence on frequency disappeared, however, when MEA was substituted as the independent variable. Chemical analyses revealed that dielectric heating of soybeans at natural moisture levels should be as effective as conventional steam toasting in reducing trypsin-inhibitor activity. PDI and NSI, but not urease, were suitable indicators of trypsin-inhibitor inactivation by dielectric heating. Lipoxygenase was completely inactivated by the dielectric heating treatments that gave suitable trypsin-inhibitor inactivation, but peroxidase activity remained relatively high, offering possible advantages for bleaching and improved soy product color. PMID- 6920416 TI - Temperature profiles in spheres due to electromagnetic heating. AB - This study predicts the steady state temperature rise in a homogeneous tissue sphere exposed to plane wave electromagnetic energy. The differential equation for heat transfer is solved, assuming heat transfer mechanisms of convection (due to blood flow), conduction, and evapotranspiration from the surface. The tissue heating is described by the specific absorption rate (SAR), which is a known function of the size and dielectric properties of the sphere and the frequency of the incident electro-magnetic energy. We consider the limiting cases of irradiation at very low frequencies, very high distance in the SAR is effectively averaged to produce a smoothly varying temperature increase. The results of this study are used to predict the maximum temperature rise in the human head, produced by an incident electromagnetic plane wave. PMID- 6920417 TI - The four T's of pediatric ophthalmology. PMID- 6920418 TI - Standardized ophthalmic echography and the health care professional. PMID- 6920420 TI - From a technical point of view: color standardization for goldmann isopters. PMID- 6920419 TI - The role of the ophthalmic nurse in helping the patient adapt to loss of vision. PMID- 6920421 TI - Fundamentals in focus: glaucoma. PMID- 6920423 TI - The concept of vision. PMID- 6920422 TI - Perspective on contact lenses. PMID- 6920426 TI - The beat goes on. Let's take the fool out of April. PMID- 6920427 TI - Patient focus. PMID- 6920424 TI - Home births. PMID- 6920425 TI - Unisex false pregnancy. PMID- 6920429 TI - LPN viewpoint: should you climb the ladder? PMID- 6920430 TI - Food additives and health. PMID- 6920428 TI - Teenage pregnancies. PMID- 6920431 TI - Breast reconstruction after mastectomy. PMID- 6920432 TI - Hospital volunteers make a reference. PMID- 6920433 TI - Hide & seek. PMID- 6920436 TI - [Nursing process - the concept and execution of problem solving]. PMID- 6920434 TI - Patient focus. PMID- 6920435 TI - [Prostaglandin system and kallikrein-kinin-system in edematous diseases]. PMID- 6920437 TI - [Nursing process - concepts in the solving process. The nursing process and major nursing theories]. PMID- 6920438 TI - [Nursing process - the concept in the problem solving process. The definition of the "problem" in the nursing process]. PMID- 6920439 TI - [Nursing process - the concept in the problem solving process. Patient information necessary for recognition of the problem and nursing assessment]. PMID- 6920440 TI - [Nursing process - keypoints in nursing process planning. Nursing care plans and evaluation plans]. PMID- 6920441 TI - [Nursing process - keypoints in nursing process planning. Problems in nursing process planning by students during clinical training]. PMID- 6920442 TI - [Nursing process - keypoints in nursing process planning. The nursing process record]. PMID- 6920443 TI - [Nursing process - keypoints in nursing process planning. Sharing of the nursing assessment]. PMID- 6920444 TI - [Nursing process - keypoints in nursing process planning. The problem vs. patient in nursing - accurate understanding of the problem]. PMID- 6920445 TI - [Nursing process - keypoints in nursing process planning. Evaluation of the expected outcome and its description]. PMID- 6920446 TI - [Nursing diagnosis for cancer patients]. PMID- 6920449 TI - [Safety of posture changes in relation to hemodynamics. A conference]. PMID- 6920447 TI - [Various modalities in cancer therapy. A discussion]. PMID- 6920448 TI - [On the approach in clinical nursing research. Discussion]. PMID- 6920450 TI - [Effect of pamphlet distribution in alleviating anxiety concerning endoscopic examination]. PMID- 6920453 TI - [Undertaking a research project - actions following selection of a theme and various problems related to these actions]. PMID- 6920454 TI - [Outline of nursing research]. PMID- 6920452 TI - [Movement therapy with the aged]. PMID- 6920455 TI - [Participant observation]. PMID- 6920451 TI - [Experiment on the stress of daily activities - energy consumption involved in shampooing in a half-reclining position]. PMID- 6920456 TI - [Field notes on pain]. PMID- 6920457 TI - [Pain: an organizational-work-interactional perspective]. PMID- 6920458 TI - [Pain expression and control in a burn care unit]. PMID- 6920459 TI - [Closing the gap between the nursing research and practice - in the case of field research]. PMID- 6920460 TI - [Teaching nursing research - the keypoints and methodology]. PMID- 6920461 TI - [The content of my course on "nursing research outline"]. PMID- 6920462 TI - Twin pregnancy: maternal-fetal nutrition. PMID- 6920463 TI - Breastfeeding twins: maternal-infant nutrition. PMID- 6920466 TI - Development of a neonatal intensive care orientation program. PMID- 6920464 TI - The subfertile couple. AB - When pregnancy is achieved through fertility awareness, there are further long range benefits to the couple: information which will permit them the choice to avoid, delay or achieve subsequent pregnancies. Thus, the opportunity for responsible parenthood continues. The goal of nursing in subfertility care is to identify factors which may contribute to lowered fertility, and to teach and/or refer appropriately. The most comprehensive single intervention may be to teach the couple awareness of their own fertility through the Billings Method of natural family planning. If conception does not occur, the couple may progress to infertility investigation, knowing that the expense, inconvenience, and possible trauma are justified. Whether pregnancy occurs or not, it is likely that the couple will have had the benefit of clarifying their relationship, further understanding their bodies, and generally growing toward fuller personhood. PMID- 6920465 TI - Nurse specialization in reproductive endocrinology. PMID- 6920467 TI - Childbearing and the concept of culture. AB - Effective nursing practice requires being free of prejudice and bias. One's outlook is not necessarily the only proper one and there is no room for hasty judgments. The professional has health at the center of her perceptual system and often finds it difficult to view health as laymen do. If she wishes to work effectively with different groups of people, she must overcome her "trained incapacity" and learn to see health and beliefs surrounding it and disease from the patient's standpoint. It would simplify matters if personal and community health could be separated from the complexities of social existence, but this cannot be done. Health practices and ideas penetrate deeply into all domains of life. Nurses would do well to adopt a way of looking at the community that gives some coherence and depth to various cultures. This concept of culture can provide an organizing frame for those details and help the specialist assume the view of the client and family. PMID- 6920468 TI - Relationship of self-concept during late pregnancy to neonatal perception and parenting profile. AB - Thirty-one gravidas were studied to examine the relationship between a woman's feelings about herself during late pregnancy, her perception of her newborn, and her profile of parenting. The Tennessee Self-Concept Scale was completed during the third trimester of pregnancy, the Neonatal Perception Inventory I at one-to two days postpartum, and the Neonatal Perception Inventory II and the Michigan Screening Profile of Parenting at four-to-six weeks postpartum. When considered separately, no positive significant relationships were found between scores on these variables. However, all subjects with negative scores on both self-concept and neonatal perception had negative scores on at least two subscales of the parenting profile. PMID- 6920470 TI - [Discussion after childbirth]. PMID- 6920472 TI - [Prolactinoma and pregnancy]. PMID- 6920469 TI - Breast milk bank. PMID- 6920471 TI - [Midwives' opinions on childbirth]. PMID- 6920473 TI - [Relationship between midwife and prospective mothers]. PMID- 6920476 TI - [Medical episode: comma-shaped bacteria causing vaginitis]. PMID- 6920474 TI - [Profile of a nurse: Ms Atsuko Maekawa, the first enterostomy therapist in private practice in Japan]. PMID- 6920475 TI - [Medical episode: Spanish oil syndrome]. PMID- 6920477 TI - [Medical topics: high frequency ventilation]. PMID- 6920478 TI - [Statistical file. Current trends at nursing schools seen in the April 1982 statistics]. PMID- 6920479 TI - [The nurse and the patient's family--a view on the patient's family through the patient]. PMID- 6920480 TI - [Significance of the family to the patient--the thought processes of patients]. PMID- 6920481 TI - [Report by the Committee on the Fundamental Issues of Family Health]. PMID- 6920482 TI - [The presence of the family to the patient--the presence of the wife or husband]. PMID- 6920483 TI - [Characteristics of the views on patients (as people) held by clinical nurses]. PMID- 6920484 TI - [Determination of the site of the enterostomy and the size of the opening--for improvement in social rehabilitation]. PMID- 6920485 TI - [Diary of a visiting nurse: home care of the handicapped child]. PMID- 6920486 TI - [Fulfillment by the mother and child: a report by a practicing midwife]. PMID- 6920487 TI - [Nursing in the European Community. The legislative bodies for implementation of the EC nursing directives and renovative measures]. PMID- 6920488 TI - [Significance of the family to the patient--an approach to the patient's family- examples where nursing intervention failed in assisting the family]. PMID- 6920489 TI - The multi-million dollar challenge--the nurse administrator's role. PMID- 6920490 TI - [Understanding the human nature - in nursing perspective]. PMID- 6920491 TI - [Client-nurse relationship: communication]. PMID- 6920492 TI - [Public health nursing practice in Korea. Concept of multi-purpose health services]. PMID- 6920493 TI - [Community health nursing approach in multi-purpose health service]. PMID- 6920494 TI - [Role and responsibility of multi-purpose health service]. PMID- 6920495 TI - [Gerontological nurse specialist: luxury or necessity?]. PMID- 6920496 TI - [A study on the usefulness of primary health care center by hospital OPB patient]. PMID- 6920498 TI - [Client-nurse relationship]. PMID- 6920497 TI - [A survey on nurses' opinion of their working uniform]. PMID- 6920500 TI - Standards of mental health nursing practice. PMID- 6920499 TI - [A study on problems in night duties of clinical nurses - centering around clinical nurses in Jeon-la North Province]. PMID- 6920501 TI - [Actions and side effects of digitalis glycosides]. PMID- 6920502 TI - [What to do in case of slander?]. PMID- 6920503 TI - [You drive the way you live]. PMID- 6920504 TI - [Medicine 2000]. PMID- 6920505 TI - [The hospital as an economic factor]. PMID- 6920506 TI - [General indications for and risks of immunoglobulin treatment]. PMID- 6920507 TI - [Training of new nurses in dealing with patients]. PMID- 6920508 TI - [Language and manners in dealing with patients and their families. A. Verbal communication in dealing with patients with a poor prognosis and their families]. PMID- 6920509 TI - [Language and manners in dealing with patients and their families. B. Verbal behavior in dealing with patients with an acute condition and their families]. PMID- 6920510 TI - [Language and manners in dealing with patients and their families. C. Verbal behavior in dealing with aged patients and their families]. PMID- 6920511 TI - [Nursing teamwork in dealing with patients and their families]. PMID- 6920512 TI - [Nurses' attitudes and changes in basic nursing education]. PMID- 6920515 TI - [Scientific and ethical approaches to human reproduction]. PMID- 6920514 TI - [Role of nursing in regional care: a short-stay program for the aged]. PMID- 6920513 TI - [Nurse as the emphatic communicator: the manners of nurses in speaking and listening to patients]. PMID- 6920516 TI - [Leadership training at Tokyo Women's Medical College Hospital]. PMID- 6920517 TI - [Nursing administration research at Toranomon Hospital. 3. Preparation for the introduction of a patient classification system]. PMID- 6920518 TI - [Need for nursing theory in nursing education and the role of research in junior colleges of nursing]. PMID- 6920519 TI - [Interactions between students and instructors in clinical conferences with special reference to the nursing plans for patients in serous conditions]. PMID- 6920520 TI - [Suggestion on the introduction of programmed learning. 1. Experimentation and the results of introducing programmed learning]. PMID- 6920521 TI - [Personality characteristics seen in the EPPS (Edwards Personal Preference Schedule) test--with special reference to student nurse personality]. PMID- 6920522 TI - [Change of curriculum in the School of Nursing, the University of Hawaii. Interview by M. Kawano]. PMID- 6920523 TI - [Terminal care practice in England. Interview by R. Komatsu and and S. Kiba]. PMID- 6920525 TI - [Role of nurses in the care of the dying patient]. PMID- 6920526 TI - [Nursing and a peaceful death]. PMID- 6920524 TI - [Pain of the dying patient: a method for rational management]. PMID- 6920527 TI - [Remaining in the nursing profession while caring for the family. A survey among nurses]. PMID- 6920528 TI - [New Clinical image of man. 5. Mental development and human interactions. A discussion]. PMID- 6920529 TI - [Allocation of nursing personnel]. PMID- 6920530 TI - [Nursing administration research at Toranomon Hospital. 4. Trial application for a patient classification system]. PMID- 6920534 TI - [Conceptual framework employed in the School of Nursing, the University of Hawaii and nursing theories in the United States. Interview by M. Kawano]. PMID- 6920531 TI - [Tasks in clinical instruction]. PMID- 6920533 TI - [Clinical training in basic nursing in a 2-year nursing program]. PMID- 6920532 TI - [Suggestion on the introduction of programmed learning. 2. How to program teaching materials on nursing]. PMID- 6920539 TI - Manifestations of guilt in an immobilized school-age child. PMID- 6920535 TI - Emergicenters and the need for a competitive regulatory approach. PMID- 6920537 TI - Failure to use siderails: when is it negligence? PMID- 6920540 TI - Contrast in prenatal preparation for mothering. PMID- 6920536 TI - Terminating treatment for newborns: a theological perspective. PMID- 6920541 TI - A survey of parent groups: prehospital admission. PMID- 6920538 TI - Human life symposium: a synopsis and critique. PMID- 6920542 TI - The super nurses of tomorrow are completing their studies today! PMID- 6920543 TI - The New South Wales College of Nursing Post-Basic Education in New South Wales. PMID- 6920544 TI - The ten hour break between shifts: facts and questions. PMID- 6920546 TI - For RNs: a conversion course to diploma in applied science (nursing) by external studies. Riverina College of Advanced Education. PMID- 6920545 TI - Mentally ill - a new definition. PMID- 6920547 TI - On your mark. PMID- 6920548 TI - Nurses in demand. PMID- 6920549 TI - What's new in special baby care. PMID- 6920550 TI - Interaction with health care personnel. Part 3. The postnatal period. PMID- 6920551 TI - Management of preterm labour. PMID- 6920554 TI - Do we expect too much of the elderly? PMID- 6920555 TI - End of exam suspense! PMID- 6920553 TI - Alternative positions for labour. PMID- 6920556 TI - Consultation Papers from the United Kingdom Central council for Nursing, Midwifery and Health Visiting. No. 5: Professional conduct. PMID- 6920552 TI - About copper bracelets and holistic midwifery. PMID- 6920557 TI - Effect of two different methods of umbilical cord care on its separation time. PMID- 6920558 TI - Collection of umbilical cord blood specimens at the time of delivery. PMID- 6920559 TI - Acceptability trial of "Milumil" artificial milk for infant feeding. PMID- 6920560 TI - A babies' home in Ghana. PMID- 6920561 TI - Women & children first: the way to raised living standards. PMID- 6920562 TI - Plasmid-mediated antibiotic resistance in methicillin-resistant Staphylococcus aureus. AB - Strains of methicillin-resistant Staphylococcus aureus (MRSA), isolated from clinical sources in Victoria, were screened for the presence of plasmid DNA. Resistance to gentamicin, kanamycin, and tobramycin was found to reside on an 18 megadalton plasmid, and resistance to chloramphenicol was mediated by a 3 megadalton plasmid. No extra-chromosomal locus was found for resistance to several other antibiotics, including methicillin. Local strains of MRSA differ from their international counterparts by the possession of extensive chromosomal resistance determinants. Together with those encoded on plasmids, these determinants are capable of neutralising almost all available antistaphylococcal antibiotics. PMID- 6920563 TI - Spread of gentamicin resistance in MRSA. PMID- 6920566 TI - The care of children requiring surgery. PMID- 6920565 TI - Pride before a fall. PMID- 6920568 TI - Check out your patient's presurgery fears. PMID- 6920564 TI - Planning operating departments No. 2. Reading architectural drawings. PMID- 6920567 TI - How to succeed against acute renal failure. PMID- 6920569 TI - Lottie tried to do everything for her husband--including our job. PMID- 6920571 TI - The patient with myasthenia gravis really needs you. PMID- 6920570 TI - Emergency! First aid for choking. PMID- 6920573 TI - Tetanus. PMID- 6920572 TI - Tube talk: principles of fluid flow in tubes. Continuing education. PMID- 6920574 TI - Ambulatory nursing: teaching patients to live with chronic orthostatic hypotension. PMID- 6920575 TI - Fear of floating...to a coronary step-down unit. PMID- 6920576 TI - Test your knowledge of contemporary nursing. Part 1. PMID- 6920578 TI - Sharing: changing course. PMID- 6920577 TI - Sharing: another definition of caring. PMID- 6920579 TI - Bringing the unconscious patient back safely: nursing makes the critical difference. PMID- 6920580 TI - Deciphering diagnostic studies: cerebrospinal fluid analysis. PMID- 6920582 TI - Managing pain in the young patient. PMID- 6920581 TI - When just about everybody gave up on Dr. Hyman... PMID- 6920583 TI - Managing pain... in the elderly patient. PMID- 6920584 TI - Taming the cardiac monitor, part 1. Earn CEU's. PMID- 6920585 TI - Respiratory acidosis. PMID- 6920586 TI - Ambulatory nursing: when a child dies at home. PMID- 6920587 TI - Emergency! First aid for spinal cord injury. PMID- 6920588 TI - Lactulose: a crucial element in treating hepatic encephalopathy. PMID- 6920589 TI - Test your knowledge of contemporary nursing, Part 2. PMID- 6920590 TI - Nursing life ethics poll. PMID- 6920592 TI - Legal aspects of nursing practice. Charting with a jury in mind. PMID- 6920591 TI - Think you're powerless? Think again. PMID- 6920593 TI - Legal aspects of nursing practice. CEU test. PMID- 6920595 TI - Legal aspects of nursing practice. Trials of an expert witness. PMID- 6920598 TI - Opinion: hospital nursing in danger: will we survive? PMID- 6920596 TI - For better retention and improved morale, try primary nursing. PMID- 6920597 TI - Decisions, decisions: guidelines for making them more easily. PMID- 6920594 TI - Legal aspects of nursing practice. Are you expert enough to be an expert witness? PMID- 6920599 TI - Variety, challenge, and new insights--the benefits of rotating shifts. PMID- 6920600 TI - When you're the teacher--turn on the television. PMID- 6920601 TI - Finding the right job fit: by assessing your own needs and goals. PMID- 6920602 TI - Finding the right job fit: by analyzing your organization. PMID- 6920605 TI - Keeping up: get your money's worth from continuing education. PMID- 6920603 TI - Finding the right job fit: by playing matchmaker with jobs and employees. PMID- 6920604 TI - Tips on increasing your professional skills: how to defuse an angry patient. PMID- 6920608 TI - Ginette Rodger, Executive Director of the Canadian Nurses' Association. PMID- 6920607 TI - Jeannine Pelland Baudry, President of the Quebec Nursing Organization. PMID- 6920609 TI - [Life in the institution with the elderly client]. PMID- 6920610 TI - [Nursing behind barriers]. PMID- 6920606 TI - Court case: how much privacy does a patient need? PMID- 6920611 TI - [Nursing behind barriers and Maison Tanguay]. PMID- 6920612 TI - [Regional meeting following professional inspection visits]. PMID- 6920613 TI - [X-rays: the health risk grows with use, but how to avoid them?]. PMID- 6920615 TI - The management of clinical specialities. 4. Nursing management in an intensive care unit. PMID- 6920616 TI - Caring for comfort. PMID- 6920617 TI - Whither research? PMID- 6920618 TI - Management information in health visiting. 2. PMID- 6920614 TI - [Therapeutic abortion: a difficult choice]. PMID- 6920619 TI - Nursing productivity in Scottish hospitals. PMID- 6920620 TI - Perspectives in nursing: how do we help incompetent colleagues? PMID- 6920622 TI - Burnin, burnout & the brightly burning. PMID- 6920624 TI - Avoiding orientation burn-out: a practical guide designed to help inservice instructors. PMID- 6920621 TI - Law for the nurse manager: unruly patients. PMID- 6920625 TI - Criteria-based performance appraisals. PMID- 6920623 TI - Mother - baby nursing. PMID- 6920626 TI - Teaching nursing assistants: a comparison of teaching nursing assistants in a university and in a hospital. PMID- 6920627 TI - A structured group approach. Morale problems. PMID- 6920628 TI - Improving management: a communication system really helped the staff members of one unit. PMID- 6920629 TI - Art & science of management: developing their independence. PMID- 6920630 TI - Hazards for radiomen on oil-rigs. PMID- 6920631 TI - Bone necrosis in divers. PMID- 6920632 TI - OH services to small industries. PMID- 6920633 TI - Safety training 3: are you getting what you paid for? PMID- 6920635 TI - Safety: exporting British expertise. PMID- 6920636 TI - OH services to small industries. PMID- 6920637 TI - Physical fitness from infancy through adolescence. PMID- 6920638 TI - Safe or sorry: exposure to radiation. PMID- 6920640 TI - Swaddling: an effective invention for pacifying infants. PMID- 6920641 TI - Mobile Health Service in an urban community. PMID- 6920639 TI - Radiation exposure levels in an intensive care nursery. PMID- 6920642 TI - Behavioral management of fecal incontinence in a child with myelomeningocele. PMID- 6920643 TI - Pediatric drug information: sun exposure and sun protection. PMID- 6920644 TI - Pediatric management problems. Hyperventilation. PMID- 6920645 TI - Premature lambs rescued from respiratory failure with natural surfactant: clinical and biophysical correlates. AB - Thirty-four Western mixed breed lambs were delivered prematurely at 120 days gestational age (term = 150 days). Four lambs were sacrificed at birth, and four lambs were sacrificed with the onset of respiratory failure (PCO2 greater than 80 torr) at about 30 min of age. The remaining lambs were treated by tracheal instillation with 50 mg of natural sheep surfactant lipid/kg body weight. These lambs were sacrificed 10 min, 40 min, 1.5 h and 3 h after surfactant treatment. Frequent blood gas and compliance measurements documented the clinical responses of the lambs. Lungs from treated lambs showed large increase relative to untreated lungs in air volumes as assessed by pressure-volume curves and by histology. However, the pressure-volume and histologic measurements did not distinguish between the posttreatment groups of lambs. Minimum surface tensions of alveolar washes fell from greater than 30 dynes/cm to 6.3 dynes/cm 10 min after treatment and again rose to 21.6 dynes/cm within 3 h. Minimum surface tensions correlated well with the PO2 values but not with the PCO2 values measured before sacrifice. The combination of dilated distal airways and atelectasis resulted from increasing surface tensions with time and mechanical ventilation and may explain the clinical deterioration without much change in the volume of gas within the airways. PMID- 6920646 TI - Developing a curriculum for the nursing service administrator role. PMID- 6920647 TI - Toward an operational definition of nursing. PMID- 6920648 TI - An educational program for the administrator's role in nursing services. PMID- 6920649 TI - The role of today's nurse executive: implications for education. PMID- 6920651 TI - Criteria for the evaluation of associate degree programs in nursing. PMID- 6920650 TI - Operationalizing learning experiences in the nursing administration practicum. PMID- 6920652 TI - Strengthening nursing services in relation to primary health care. PMID- 6920654 TI - Views on vital issues affecting nurses and nursing in the Philippines. PMID- 6920653 TI - Family planning concept. PMID- 6920655 TI - Consultative workshop on nursing administration and supervision. PMID- 6920657 TI - Hypertension knowledge in a Hispanic community. AB - Hypertension knowledge of 330 Hispanic subjects was assessed in a community study using a Hypertension Knowledge Interview Schedule (HKIS). Six areas of hypertension knowledge, including definition, etiology, diagnosis, risk factors, treatment, prognosis, and sequelae were assessed. Of the subjects, 64 percent had adequate knowledge and 34 percent inadequate knowledge of hypertension. Only 28 percent knew the correct definition; only 3 percent knew that the etiology was unknown. The Hispanic subjects were knowledgeable about risk factors and treatment. More than half the Hispanics were aware of the cardiovascular sequelae of hypertension. PMID- 6920656 TI - Effects of information about a threatening procedure on patients' expectations and emotional distress. AB - A quasi-experimental study was conducted to examine the effects of information about an impending threatening event (barium enema) on subjects' expectations and the intensity of their emotional response to the event. Twenty subjects were assigned to one of two information conditions: sensation of procedure. Prior to receiving any information, all subjects completed a preinformation sensation inventory and the trait portion of the State-Trait Anxiety Inventory (STAI). A taped message of either sensation or procedural information was heard, followed by completion of the post-information sensation inventory. After the barium enema, all subjects completed the post-procedure sensation inventory and the state portion of the STAI. In neither the expected sensations (expectations) reported prior to hearing information or the responses provided after the procedure (actual experiences) were there significant differences between the two groups. However, after hearing the information, significant differences in reported expected sensations were found. Subjects receiving sensation information reported significantly less anxiety and expectations more congruent with their actual experiences than did subjects receiving procedural information. PMID- 6920658 TI - Disconfirmation in dysfunctional communication. PMID- 6920660 TI - Using different body positions to reduce discomfort from dorsogluteal injection. PMID- 6920659 TI - Effects of lifting techniques on energy expenditure: a preliminary investigation. AB - A preliminary study of the effects of different lifting techniques (mechanical lift, rocking axillary, self-lift, shoulder-assist, and straight-pull) was conducted. Fourteen female subjects participated. Measures of oxygen consumption, heart rate, respiratory rate, and blood pressure were recorded at six one-minute intervals during baseline and lift phases. Analyses of variance (ANOVAs) were conducted on each measure for each phase using a two-factor repeated factor. In the baseline phase, no significant differences were obtained for the lift factor. The time factor yielded significant main effects for oxygen consumption, p less than .0001, and heart rate, p less than .0001. These effects were associated with one and two minutes following the subject's return to bed. In the lift phase, significant main effects were obtained for lift and time factors on oxygen consumption, p less than .0005 and p less than .0001. Significant main effects were obtained for the time factor on heart rate, p less than .0001, respiratory rate, p less than .0006, and systolic blood pressure, p less than .0045. Finally, a significant main effect was noted for the lift factor on diastolic blood pressure, p less than .022. These findings suggest that the mechanical lift is the most taxing on the person being lifted. PMID- 6920661 TI - Construction of a scale to measure load, power, and margin in life. AB - The development of an instrument to measure load, power, and margin in life (MIL) is described. Validity was established through factor analysis and the know groups approach to construct validity. Stability was tested through a test-retest reliability, and Cronbach alpha reliability coefficients were obtained to test for internal consistency. Subjects consisted of 146 adult men and women volunteers for testing Form 1, later revised to Form 2. Form 2 was given to 103 volunteers; of these 66 were repeaters from the Form 1 testing; 37 were new subjects. Item analyses were performed and used to reduce the original 211 items to 94 for Form 3 of the scale. PMID- 6920662 TI - A patient satisfaction measure as a criterion to evaluate primary nursing. AB - The Risser Patient Satisfaction Scale was used to evaluate the effectiveness of implementing the key concepts of primary nursing. An experimental control design was used. Forty-six subjects from two units completed the questionnaire. Estimates of reliability and homogeneity are reported. There is reason to question the discriminant validity of the subscales. No significant differences were obtained between the units on any of the subscales or total scale score. A number of explanations are offered for interpreting the measuring of the nonsignificance of the differences. Work need to continue on revising existing patient satisfaction measures or developing new ones. Other criteria with theoretical importance should be used in conjunction with satisfaction measures in assessing the effects of primary nursing. PMID- 6920663 TI - Assessing family functioning across three areas of relationships. PMID- 6920664 TI - The challengers, interactors and mainstreamers: second step education and nursing roles. AB - What impact have post-licensure or "Second Step" programs for nurses had been upon experienced nurses? How successful have they been in developing more professional orientations among nurses trained for a technical role? A factor analysis of longitudinal data from 236 nursing students in six Second Step programs revealed that students entering these programs varied greatly in professional attitudes. Three types of students--the challengers, the interactors, and the mainstreamers were differentiated, by their contrasting nursing styles as well as by diverse sociopolitical views and personality characteristics. Data indicated that, at graduation, students in all three groups perceived themselves as more professionally involved, committed, and competent, but they did not change similarly in other areas of life. The challengers and the interactors made significant changes in their sociopolitical views and in some personality characteristics, while the mainstreamers made fewer changes and maintained greater consistency from entry to graduation. Second Step education promoted professional development, but its impact upon other areas of life varied, depending upon the students' receptivity and readiness for change. PMID- 6920665 TI - GUTS: teaching assertiveness skills by stimulation and gaming. PMID- 6920666 TI - Choosing and using a statistical consultant. PMID- 6920667 TI - Nursing students' attitudes toward sexually active older persons. AB - This study investigated the attitudes of senior baccalaureate nursing students toward geriatric sexuality. Two separate experiments used vignettes as an unobtrusive measure of attitudes toward sexual activity in an older man or woman who was depicted as either married or widowed. All subjects read a vignette concerning a 68-year-old person who was temporarily living in a nursing home. Half read that the person was sexually active; there was no mention of sexual activity for the remaining subjects. Subjects evaluated the person on a 10-item questionnaire, employing 0-to-9 bipolar rating scales for such traits as well adjustedness, cheerfulness, and mental alertness. Regardless of the stimulus person's gender, or marital status, subjects showed a significant bias favoring the sexually active older person in both experiments. Implications for nursing practice are discussed. PMID- 6920668 TI - Planning patient care - 3. One ward sister's view of changing over to written care plans. PMID- 6920669 TI - Measurement of nursing skills--the search for a suitable assessment tool. PMID- 6920670 TI - Planning patient care - 3. The reactions of nursing staff to the introduction of care plans. PMID- 6920671 TI - Can we measure quality?. Interview by De Marks-Maran. PMID- 6920674 TI - Home sweet hospital: the road to institutionalization. PMID- 6920672 TI - Racism: 'I often ask God why he allows black people to suffer like this'. PMID- 6920673 TI - Who's holding the purse-strings? PMID- 6920675 TI - Home sweet hospital: reality orientation in Tuscaloosa. PMID- 6920677 TI - Supervised Antabuse in alcoholism. PMID- 6920676 TI - Home sweet hospital: behavioural analysis in the care of the elderly. PMID- 6920678 TI - Renal replacement therapy. 5-1. Acute renal failure. PMID- 6920679 TI - Renal replacement therapy. 5-2. The nursing care of patients in acute renal failure. PMID- 6920681 TI - Of mind and matter. PMID- 6920680 TI - Caring is sharing. Improving the quality of patient care. PMID- 6920682 TI - Integrating theory and practice in nursing-2. PMID- 6920683 TI - Wound care. No. 10. Wound, sinus or fistula? PMID- 6920685 TI - Falklands special: saving lives in the South Atlantic. PMID- 6920684 TI - Rampton goes to the community. PMID- 6920686 TI - Falklands special: a family at sea. PMID- 6920687 TI - Spanner in the works. PMID- 6920690 TI - Changing the environment: take a new look at your ward. PMID- 6920689 TI - 9-2. Hepatitis in European dialysis centres. PMID- 6920688 TI - Drama therapy. PMID- 6920691 TI - Changing the environment: institution or home. PMID- 6920693 TI - Planning patient care-4. Carrying out nursing care activities. PMID- 6920692 TI - And did those feet. PMID- 6920695 TI - Flying the wounded home. PMID- 6920696 TI - It takes three to tango. PMID- 6920694 TI - An experiment in nurse education at Southampton University-1. PMID- 6920698 TI - Nursing in Hong Kong. PMID- 6920697 TI - COHSE 1982: from women's rights to social rites. PMID- 6920699 TI - Sexual attitudes and behaviour in patients attending a Special Clinic. PMID- 6920700 TI - Renal replacement therapy: 10-1. JBCNS renal courses. PMID- 6920701 TI - Epilepsy - 1. Living with epilepsy. PMID- 6920702 TI - The inspector calls. PMID- 6920704 TI - A delivery bed with a difference. PMID- 6920703 TI - Systems of life No 91. Systems and signs: nervous system. Testing motor function- 2. PMID- 6920705 TI - An experiment in nurse education at Southampton University--2. PMID- 6920706 TI - Continuous assessment two years on. PMID- 6920707 TI - The Commonwealth scene. PMID- 6920708 TI - WACN: the nurse as an equal partner in the health team. PMID- 6920710 TI - RCM Annual Meetings. Hands across the divide. PMID- 6920714 TI - Some thoughts on stress to staff in neonatal units. PMID- 6920711 TI - Caught in the crossfire. PMID- 6920713 TI - A unique honour. Interview by Laurence Dopson. PMID- 6920712 TI - A lonely burden. PMID- 6920709 TI - RCM Annual Meetings. New frontiers. PMID- 6920716 TI - Counselling in psychiatric nursing--1. PMID- 6920715 TI - Nursing care study: left nephrectomy. PMID- 6920718 TI - Epilepsy--2. People with epilepsy in the job market. PMID- 6920717 TI - Renal replacement therapy. 11. The cost of treating chronic renal failure. PMID- 6920719 TI - Drug overdose--the national picture. PMID- 6920721 TI - Continuing education. Can it be legislated? PMID- 6920720 TI - Mountaineering with the mentally handicapped. PMID- 6920722 TI - When nurses were national heroines: images of nursing in American Film, 1942-5. PMID- 6920723 TI - Clinical evaluation of the nursing instructor: another dimension of professional accountability. PMID- 6920724 TI - Reflections of a psych nurse. PMID- 6920725 TI - Joint appointments: challenge for nursing. PMID- 6920727 TI - Preparing for a key post. PMID- 6920726 TI - Paediatric nursing: innocent and loveable, but... PMID- 6920728 TI - Munchausen's syndrome: I found that I mattered. PMID- 6920730 TI - Clinical dissent: why torticollis is a chronic condition among clinical nurses. PMID- 6920729 TI - Munchausen's syndrome. When a doctor turns detective. PMID- 6920731 TI - Employment law 1. The importance of being frank. PMID- 6920733 TI - Profile on Marian Hendry--to Rampton with love. Interview by Tamara Ross. PMID- 6920732 TI - Postbasic nursing procedures 11. Plaster cast.2. PMID- 6920735 TI - Ectopic pregnancy: on the increase. PMID- 6920734 TI - Issues in nursing conference 3. That uncertain knock on the door. PMID- 6920736 TI - Ectopic pregnancy: out of place. PMID- 6920737 TI - The way we were. PMID- 6920738 TI - Lifting aids: handle with care. PMID- 6920740 TI - Geriatric incontinence: restoring self respect. PMID- 6920739 TI - Students' forum: cardiac arrhythmias. PMID- 6920741 TI - Nursing care study: the whole team won. PMID- 6920742 TI - Family life: the long shadow of a sibling. PMID- 6920743 TI - Clinical comment: Simon's shadow: why the nurse should have a bigger role. PMID- 6920744 TI - Careers: anaesthetic nursing: wide awake to care. PMID- 6920747 TI - Group dynamics: forming, storming, norming and performing. PMID- 6920745 TI - Community forum 7: District nursing: the role of research. PMID- 6920746 TI - Community forum 7: District nursing: a change of balance. PMID- 6920748 TI - Hypnosis: it's here to stay - and is a useful concept. PMID- 6920750 TI - Pacemakers. 3. The sister's view. PMID- 6920751 TI - Living it out - or in? PMID- 6920752 TI - Research. In the balance. PMID- 6920749 TI - Pacemakers. 3. A unit of efficiency. PMID- 6920754 TI - The biology of ageing. 3. Down the line. PMID- 6920755 TI - Disposable aids. 2. Dry nights. PMID- 6920756 TI - Employment law. 4. Prejudice at work. PMID- 6920753 TI - Baroque medicine: how a cup of Aunt Ida's hot air rescued a sailor. PMID- 6920757 TI - White coats everywhere. PMID- 6920759 TI - Spinal jackets: Baycast moulding. PMID- 6920758 TI - Anytown anecdotes. She doesn't like strangers. PMID- 6920760 TI - Education: making the important measurable. PMID- 6920761 TI - Nursing care study: slow steps to a memory. PMID- 6920762 TI - Staffing: the outlook for care. PMID- 6920764 TI - [Development and work forms at the prospect of health care-77]. PMID- 6920765 TI - [Reduced government subsidy for health care planning in county council schools]. PMID- 6920763 TI - Careers: research: There for the taking. PMID- 6920767 TI - [How we work in pediatric nursing education in Halmstad's Vardskolan]. PMID- 6920766 TI - [Knowledge dissemination about - for - and of the elderly]. PMID- 6920768 TI - [Project-oriented work method in social service planning in a county council college program]. PMID- 6920769 TI - [Education concerning social service reorganization]. PMID- 6920770 TI - [A brief presentation of social service legislation]. PMID- 6920771 TI - [You need relief and someone to talk to. Interview by Inger Hartl]. PMID- 6920772 TI - [Newborn infants--baths or spongings?]. PMID- 6920775 TI - [Continued education in the Alnang school]. PMID- 6920774 TI - [Study day in Umea: comprehensive care - development of a new area of skills]. PMID- 6920777 TI - [Continued education within a county council]. PMID- 6920776 TI - [To work as instructor in an individual course in a community college]. PMID- 6920773 TI - [Hospital-connected home care from the family and patient's viewpoint]. PMID- 6920778 TI - [Courses for school personnel 1982-83]. PMID- 6920779 TI - [Junk culture--a mental rape against children!]. PMID- 6920780 TI - [Patient nutrition at home]. PMID- 6920782 TI - [Scientific research]. PMID- 6920781 TI - [We shall educate differently: midwives]. PMID- 6920783 TI - [Rehabilitation in diseases of the motor apparatus]. PMID- 6920785 TI - [Documentation in the nursing process]. PMID- 6920784 TI - [Tuberculosis]. PMID- 6920786 TI - [Professional improvement]. PMID- 6920787 TI - [Discussion on the profession]. PMID- 6920788 TI - [Biological rhythms in medicine]. PMID- 6920789 TI - [Not only our affair: a voice in the discussion]. PMID- 6920790 TI - [Provincial nurse inspector]. PMID- 6920791 TI - [Education system but which?]. PMID- 6920792 TI - [We shall educate differently: nurses]. PMID- 6920795 TI - [Health service needs and tasks]. PMID- 6920794 TI - [Rehabilitation in the community]. PMID- 6920796 TI - [Work in the community]. PMID- 6920793 TI - [Nutrition: its effect on health]. PMID- 6920797 TI - [Nursing process: a summation]. PMID- 6920798 TI - [In Nigeria]. PMID- 6920800 TI - [Circadian rhythms of the healthy human being]. PMID- 6920799 TI - [Billing's ovulation method]. PMID- 6920801 TI - [Specialization in nursing: let us organize it well]. PMID- 6920802 TI - [Community midwife]. PMID- 6920804 TI - Charting: "The truth, the whole truth". PMID- 6920805 TI - Legal case briefs for nurses. CT: $1.5 million award: issue of R.N. care. OH: psychiatry: right to leave facility. PMID- 6920803 TI - [Midwife]. PMID- 6920806 TI - M.D. liability for R.N. errors: the Ohio rule. Case in point: Baird v. Sickler, M.D. (433 N.E. 2d 593 - Ohio). PMID- 6920807 TI - The family is the patient. PMID- 6920809 TI - The occupational health nurse. PMID- 6920808 TI - Nursing as a profession: roots from the past support growth into the future. PMID- 6920810 TI - [No prolonged use without adjusted explanations]. PMID- 6920811 TI - [A patient dependency chart in studies in a geriatric ward of the Grenoble University Hospital Center (Dr. Dubos' service)]. PMID- 6920814 TI - [Party at the hospital: necessity or illusion for the nursing staff?]. PMID- 6920813 TI - [Isabelle]. PMID- 6920812 TI - [Vitiligo]. PMID- 6920815 TI - [The adolescents with myopathies become young adults at Brasset]. PMID- 6920816 TI - [Happy as a patient at the doctor]. PMID- 6920817 TI - [Ariadne's daughter ... Aladdin's lamp]. PMID- 6920818 TI - [Tuberculous disease: treatment]. PMID- 6920820 TI - Happening now: the decline and fall of paperwork. PMID- 6920819 TI - [Drainage and aerosol, technics and practical importance]. PMID- 6920821 TI - DIC: the deadly paradox. PMID- 6920822 TI - Pneumonia: aggressive treatment is the key. PMID- 6920823 TI - Confessions: don't argue ... do something! PMID- 6920824 TI - The fine art of giving a physical. Examining the thorax and respiratory system. PMID- 6920825 TI - Two diagnostic procedures that demand your all-out care. PMID- 6920826 TI - Legally speaking. Can you be fired for speaking out? PMID- 6920827 TI - Sound off! Two rather desperate calls for action. PMID- 6920828 TI - Moments that matter: "Into thy hands'. PMID- 6920829 TI - The ultimate nightmare: fire in the OR! PMID- 6920830 TI - Proning can save you time. PMID- 6920833 TI - [Paranoia and depression]. PMID- 6920831 TI - RNAO President calls for new attitudes towards health care costs. PMID- 6920832 TI - [Sensitive paranoia or "delirium of governesses"]. PMID- 6920835 TI - [Passing to action in paranoia]. PMID- 6920836 TI - [Tale of the hospitalization of a persecuted paranoid patient]. PMID- 6920834 TI - [Paranoia--a multi-faceted disease]. PMID- 6920837 TI - [Paranoia: foreword]. PMID- 6920838 TI - [Therapeutic relation and paranoia]. PMID- 6920839 TI - [Responsibility of the paranoid and mental patients in general]. PMID- 6920840 TI - [The body as object, subject and mediator of a relationship]. PMID- 6920842 TI - [For discussion: development of the nursing profession as a major subject level]. PMID- 6920843 TI - [Attitude to aging among the elderly]. PMID- 6920841 TI - [Clinical aspects of paranoia]. PMID- 6920844 TI - [Rationalization and motivation]. PMID- 6920845 TI - [Abuse of professional title?]. PMID- 6920846 TI - [Are there professional nurses?]. PMID- 6920847 TI - [Government's strategy for the health sector]. PMID- 6920848 TI - [Professionalization of nursing]. PMID- 6920850 TI - [District council - an effective organizational tool]. PMID- 6920851 TI - [Necessary "fill up" for the resource strength]. PMID- 6920849 TI - [The elderly will have to play a really social role. Interview by Michel Salomon]. PMID- 6920852 TI - [Hadassah in Jerusalem: nursing education and district health services]. PMID- 6920853 TI - [Final guidelines: assurance of rights for nursing home patients]. PMID- 6920854 TI - [Is education a benefit?]. PMID- 6920855 TI - [Health visitors' role in European health services]. PMID- 6920856 TI - [Do hospitals produce nursing home patients?]. PMID- 6920857 TI - [Nursing homes in Oslo]. PMID- 6920859 TI - [Hospital hygiene advice in Norway]. PMID- 6920860 TI - [Nurses and military health services]. PMID- 6920862 TI - [Pain and pain treatment - once again]. PMID- 6920861 TI - [Psoriasis - more than a flaking skin]. PMID- 6920858 TI - [Methods for calculating personnel needs in institutions and health services]. PMID- 6920863 TI - [Patient classification system]. PMID- 6920864 TI - [Nurses cannot avoid political activities. Interview by Bjorn H. Larsen]. PMID- 6920865 TI - [From the Oslo-studies: most over-80-year-olds are active and alert]. PMID- 6920867 TI - [Education discussions: open letter to my professional colleagues]. PMID- 6920866 TI - [Hepatitis B]. PMID- 6920868 TI - [Nurses' role--how has it changed?]. PMID- 6920869 TI - [Profession and research: nursing research--for the patients' sake. Interview by Rigmor Vendt]. PMID- 6920870 TI - [Profession and research: ethical guidelines for nursing research in Scandinavia]. PMID- 6920871 TI - [ADP and future perspectives]. PMID- 6920872 TI - [Care for the aged in our neighboring countries: glimpse from Malmo and Helsinki studies]. PMID- 6920873 TI - [Government drug control informs: chemical disinfectants in use in health and nursing care]. PMID- 6920874 TI - [Fellow men?]. PMID- 6920875 TI - [Nursing services--physicians' responsibility?]. PMID- 6920876 TI - [Profession and research: health care needs, knowledge and science perspective]. PMID- 6920878 TI - [Significant negotiations' results approved]. PMID- 6920879 TI - [New framework for student activities]. PMID- 6920877 TI - [Nurses in Sundbyvang. Treatment reminds one of quackery]. PMID- 6920880 TI - [10-year struggle for 24-hour home nursing ends in victory]. PMID- 6920881 TI - [Team work between families and the professionals. Prevention in young children in Denmark. 9]. PMID- 6920882 TI - [Illustration of the effects of goal-directed care]. PMID- 6920883 TI - [Are those standards of psychological care?]. PMID- 6920884 TI - [Appeal from a home care nurse in Norrebro in Copenhagen: dying elderly lie alone and fearful in their apartments]. PMID- 6920885 TI - [Looking for examiners for the final nursing examination]. PMID- 6920886 TI - [Education and information will strengthen ADP-discussion]. PMID- 6920887 TI - [Physician backs up nurse's criticism: I was dumbfounded the first time I came to Sundbyvang. Interview by Kirsten Sorrig]. PMID- 6920889 TI - [Ulcer treatment which can save time and suffering]. PMID- 6920888 TI - [Untruthful and distorted criticism of Sundbyvang. Interview by Pia Kristensen]. PMID- 6920891 TI - [Drug utilization in Sundbyvang: do 13 patient receive 200 mg of Tegretol twice a day]. PMID- 6920890 TI - [A model for continuing clinical education]. PMID- 6920892 TI - [Nurse visited Sundbyvang: visitors don't come into the wards which are criticized]. PMID- 6920893 TI - [World's best capital city]. PMID- 6920894 TI - [Professional identity next to opinions which were insults]. PMID- 6920895 TI - [Good experiences with offer of home visits to pregnant women]. PMID- 6920896 TI - [Challenges for Danish nurses in Gizan]. PMID- 6920897 TI - [Warning against course which leads to everybody fighting everybody else]. PMID- 6920898 TI - [Development determined by cooperation]. PMID- 6920899 TI - [Trust stands and falls with results]. PMID- 6920900 TI - [We are in need of cooperation with organizations]. PMID- 6920901 TI - [Building up of trust means most]. PMID- 6920902 TI - [Do we treat the elderly properly?]. PMID- 6920903 TI - [Medicine man's work in the bush: people survive with superstition and boundless trust]. PMID- 6920904 TI - [Who will be responsible for the crisis in Sundbyvang place?]. PMID- 6920905 TI - [A story about one out of many]. PMID- 6920907 TI - [New technology will mean improved nursing care quality]. PMID- 6920906 TI - [We must materialize the undefinable: work stress]. PMID- 6920908 TI - [Inge Andersen in her farewell address: years in the Danish Nursing Council have been instructive]. PMID- 6920910 TI - [Nurses' participation in ADP-project activities: we want to understand so that we are part of the decision]. PMID- 6920909 TI - [Give in to a good time for a short time]. PMID- 6920911 TI - [Surprising turn in the Sundbyvang-subject; doctor Bo Engberg does not want to participate in further discussion]. PMID- 6920912 TI - [Discussion on pension assessment: it is an assessment of collective social arrangements]. PMID- 6920914 TI - [Wishes at the congress: increased education and exemption of service for representatives]. PMID- 6920913 TI - [Congress debate on conditions of nursing education: it is especially important that we now stand together]. PMID- 6920916 TI - [Solidarity fund to be established in 1983]. PMID- 6920915 TI - [Congress discussion about "Sygeplejersken": need for articles in a language which is easy to understand]. PMID- 6920917 TI - [Unemployment fund meets with sound approval]. PMID- 6920918 TI - [Let it not be a cry for help in vain]. PMID- 6920919 TI - [Nurses have a bad conscience: patients are sent home without having had surgery]. PMID- 6920920 TI - [Creative thinking of instructors and students in psychological care. Creativity in instruction in expressive function. 2]. PMID- 6920921 TI - [82 congress: modest majority against primary voting in negotiations]. PMID- 6920923 TI - [Therefore 'no' to the ECC social service and health sector]. PMID- 6920922 TI - [Object clause under discussion: congress declined proposal to support peace and disarmament]. PMID- 6920924 TI - [Study of life style with a Bricker bladder]. PMID- 6920925 TI - [Use of a clinical patient care plan in the ambulatory clinic]. PMID- 6920926 TI - [The need for nurses does not agree with the supply of education]. PMID- 6920927 TI - ["Nurse's bladder" - a change in normal urination urge as a result of external circumstances]. PMID- 6920928 TI - [Self catheterization - an aid to patients who cannot empty the bladder with normal urination]. PMID- 6920929 TI - [Handling of primary election was shocking]. PMID- 6920930 TI - [A town where hope alternates with despair]. PMID- 6920931 TI - [Letter to Rodskilde College]. PMID- 6920933 TI - [Sundbyvang's 189 mentally retarded residents: hostages in a game of lacking political determination. Interview by Pia Kristensen]. PMID- 6920932 TI - [Broad added interest in breast feeding]. PMID- 6920934 TI - [Vacation time and problem time]. PMID- 6920935 TI - [Risk factors in our 80-year-old and over residents: additional efforts must be made towards new ways]. PMID- 6920937 TI - [Listening to life and experience. Communication with the patient in the general hospital. I]. PMID- 6920936 TI - HLA antigens and Bf allotypes in SLE: evidence for the association being with specific haplotypes. AB - The clinical features and HLA types of 67 unrelated patients with Systemic Lupus Erythematosus (SLE) were analyzed. The results showed: 1. An increase in frequencies of A1, B8, and DR3. These antigens are in close linkage disequilibrium and our data show that susceptibility to SLE is associated with the presence of all three antigens, implicating the specific haplotype which bears these antigens. 2. An increase in frequency of DR2, but not A3 or B7, these latter two antigens being in linkage disequilibrium with DR2. 3. 73.3% of the 54 Caucasoid SLE group were either B8 and/or DR2. This is in comparison with 37.5% in the controls and the difference is significant (p less than 0.001). 4. There was no association apparent between extent of disease, particular organ involvement and level of circulating antibodies to double stranded DNA with any HLA region product. PMID- 6920938 TI - [Nursing care of a cancer patient with pain]. PMID- 6920939 TI - [Pain control: pain controls life]. PMID- 6920940 TI - [Supporting self care, the essence of nursing? I. A critical analysis of J. van den Brink-Tjebbes' nursing theory]. PMID- 6920941 TI - [Listening to life and experience. Communication with the patient in the general hospital. II]. PMID- 6920942 TI - [Preventive measures in working with cytostatic agents]. PMID- 6920943 TI - [Nurses in emergency health services and the law on occupations in individual health care]. PMID- 6920944 TI - [Vitamins. I. Fat-soluble vitamins]. PMID- 6920945 TI - [Cholesterol, the coming end of a myth]. PMID- 6920946 TI - [Kallikrein-kinin system of the blood and microcirculation following surgical treatment of gastric and duodenal ulcer]. PMID- 6920949 TI - Nursing care of the patient following radiotherapy. PMID- 6920948 TI - Malpractice in nursing -- Part II. PMID- 6920947 TI - [Components of kallikrein-kinin system in experimental and clinical neuroallergy]. PMID- 6920950 TI - Nursing care of the terminally ill. PMID- 6920951 TI - Nursing care of the patient on chemotherapy. PMID- 6920952 TI - The nursing process. PMID- 6920954 TI - Enhancing old age. PMID- 6920955 TI - [Agreements on titles in health and nursing care: everybody is a nurse]. PMID- 6920953 TI - Medium term programme in nursing/midwifery and the nursing process. PMID- 6920957 TI - [Is a smoke-free environment a Utopia?]. PMID- 6920956 TI - [Team work for progress between public sector and private industry]. PMID- 6920958 TI - [Margareta Callersten, participant in abortion research: don't choose abortion because it appears a better solution. Interview by Monica Trozell]. PMID- 6920959 TI - [Gunilla, nurse anesthetist in gyn operating room: finds much left to do where prevention is concerned]. PMID- 6920960 TI - [Inga, midwife: without the new abortion legislation illegal abortions would increase]. PMID- 6920961 TI - [Elisabeth, supervisory nurse: patients must be supported irrespective of what we ourselves think about abortion]. PMID- 6920962 TI - [Stop lying to patients say breast cancer patients in new book]. PMID- 6920963 TI - [Psychiatric care in Blekinge moves into the community]. PMID- 6920964 TI - [Easy to treat patients in their usual home environment]. PMID- 6920965 TI - [Health care role--a "new" and important study circle]. PMID- 6920967 TI - [Profile: Maj Eriksson, health care administrator. Interview by Jan Thomasson]. PMID- 6920966 TI - [Don't drink alcohol during pregnancy. Interview by Kristina Johnson]. PMID- 6920968 TI - [Discussion on Soderby-study: Health Care Planning and Rationalization Institute has prepared a poor and uncritical evaluation]. PMID- 6920970 TI - [Study shows patients are satisfied with nurses' advice]. PMID- 6920969 TI - [Proposal on guidelines for recruiting and employment. How shall experience be evaluated in relation to education?]. PMID- 6920971 TI - [Physicians are no guarantee for good education]. PMID- 6920972 TI - [Karin Soder reverses herself: there is no reduction in occupational health services]. PMID- 6920974 TI - [Health care research. Large concentration of research studies in Orebro. Country council has built up its own organization]. PMID- 6920973 TI - [Committee proposes: cancer test every 3d year for women over 60]. PMID- 6920975 TI - [School nurse's 900 records destroyed in a fire:only half of the children know which vaccinations they have received. Interview by Kristina Lindgren]. PMID- 6920976 TI - [Big venture to improve children's health]. PMID- 6920978 TI - [Higher status in the USA]. PMID- 6920979 TI - [Many "blood innovations" produce need for longer education. Interview by Jan Thomasson]. PMID- 6920977 TI - [Shortened education, little continued education, new need for competence. Will future laboratory assistants be worse than today?]. PMID- 6920980 TI - [Questions on employee fund: hot potatoes in Orebro]. PMID- 6920982 TI - [Drain southward is a mere memory. Interview by Kristina Lindgren]. PMID- 6920981 TI - [Government proposal strikes hard at unemployment fund; dues must increase a lot]. PMID- 6920983 TI - [Facts on unemployment]. PMID- 6920984 TI - [Health care research. She builds up a new research activity: Astrid is Sweden's only professor in health care. Interview by Jan Thomasson]. PMID- 6920985 TI - [Monica was reported when she refused to give Depo-Provera. Interview by Susanne Gare]. PMID- 6920986 TI - [Sweden approved of Depo-Provera sales promotion in developing countries. Interview by Elisabeth Magnusson]. PMID- 6920987 TI - [Helicopters arrive with the injured at a field hospital somewhere in Sweden]. PMID- 6920988 TI - [18 percent are without a job after education]. PMID- 6920989 TI - [Health care research. Ingrid Heidenborg in her doctoral thesis: health care does not satisfy patients' basic needs]. PMID- 6920990 TI - [Health care research. Research coordination in Falun: important to apply results of research in health care. Interview by Kristina Lindgren]. PMID- 6920991 TI - [Fight about physicians' working time is finished]. PMID- 6920992 TI - [Profile: Kerstin Leijd-Tidbecks, Vardfacket's artist. Interview by Jan Thomasson]. PMID- 6920993 TI - [Care of the dying has improved - but there is still much to learn]. PMID- 6920994 TI - [Agreement in Falun: physicians back to education]. PMID- 6920995 TI - [Alas Varmeland you beauty, in the grip of a health care crisis. Consequences of physicians' conflict: when physicians called in sick departments were closed]. PMID- 6920996 TI - [Report on psychiatry: Health Care Planning and Rationalization Institution finds middle course among schools]. PMID- 6920997 TI - [In Tierp's health center Liz and Margareta can be found, they help diabetics with the right diet and how to live better. Interview by Inger Lernevall]. PMID- 6920998 TI - [Health by the people - ambitious venture in primary care]. PMID- 6920999 TI - [Theater group involved in nursing school education]. PMID- 6921000 TI - [Swedes abroad lost their social security]. PMID- 6921003 TI - A very special camp. PMID- 6921002 TI - Political action for professionalism: President's address. PMID- 6921001 TI - [Effect of the combined use of antibiotic-resistant bifidobacteria and the corresponding antibiotics on the survivability of irradiated mice]. AB - The combined administration of antibiotic-resistant bifidobacterial strains and the corresponding antibiotics (ampicillin, gentamycin or kanamycin) leads to a greater increase in the survival rate of irradiated mice than the administration of antibiotics only and is a promising method for the treatment of post irradiation intestinal dysbacteriosis. PMID- 6921005 TI - Newborn cyanosis. PMID- 6921006 TI - Churches as settings for teaching physical assessment. PMID- 6921004 TI - Pedal edema in the cancer patient. PMID- 6921009 TI - ANA votes federation. PMID- 6921007 TI - Significance of dead space in syringes. PMID- 6921010 TI - When medical standards apply to nurse practitioners. The legal side. PMID- 6921008 TI - "Don't let me fall". PMID- 6921011 TI - If the shoe fits. PMID- 6921014 TI - The nature of wound healing. PMID- 6921012 TI - [Effect of bradykinin and kallikrein on plasma proteins in the inflammatory process in rabbits]. PMID- 6921013 TI - Health belief model aids understanding of patient behavior. PMID- 6921015 TI - Wound healing in the immunosuppressed host. PMID- 6921018 TI - Bringing nurses back into the OR. PMID- 6921017 TI - A nursing workshop for medical students. PMID- 6921016 TI - Promoting healing of trauma wounds. PMID- 6921019 TI - Learning budget game is key to your success as an OR manager. PMID- 6921020 TI - Correcting transposition of the great arteries. PMID- 6921021 TI - Hints for dealing with employee stress. PMID- 6921022 TI - Epiglottitis in pediatric patients. PMID- 6921023 TI - Pediatric patients deserve special instruments, supplies. PMID- 6921024 TI - International nursing: human experimentation and medical ethics. PMID- 6921025 TI - The nurse and the law: the significance of disclosure. PMID- 6921026 TI - Drugs in current use: baclofen. From the Royal Melbourne Hospital Pharmacy Department. PMID- 6921027 TI - Myelomeningocele--the spina bifida effect. PMID- 6921029 TI - Nursing in the outback-- a survey of training needs. PMID- 6921030 TI - A course for psychiatric nurse therapists. PMID- 6921028 TI - Bed area falls: a recent report. PMID- 6921031 TI - Energy and hospitals. PMID- 6921032 TI - Hitting hard without striking: what courage and cohesion did for the nurses at Victoria's W.G.H. PMID- 6921034 TI - Caring for the dying: the nurse's relationship with the dying person. PMID- 6921033 TI - The nurse who came in from the cold. PMID- 6921035 TI - The kinetics of hydrolysis of some extended N-aminoacyl-L-arginine methyl esters by human plasma kallikrein. Evidence for subsites S2 and S3. AB - Subsites in the S2-S4 region were identified in human plasma kallikrein. Kinetic constants (kcat., Km) were determined for a series of seven extended N-aminoacyl L-arginine methyl esters based on the C-terminal sequence of bradykinin (-Pro-Phe Arg) or (Gly)n-Arg. The rate-limiting step for the enzyme-catalysed reaction was found to be deacylation of the enzyme. It was possible to infer that hydrogen bonded interactions occur between substrate and the S2-S4 region of kallikrein. Insertion of L-phenylalanine at residue P2 demonstrates that there is also a hydrophobic interaction with subsite S2, which stabilizes the enzyme-substrate complex. The strong interaction demonstrated between L-proline at residue P3 and subsite S3 is of greatest importance in the selectivity of human plasma kallikrein. The purification of kallikrein from Cohn fraction IV of human plasma is described making use of endogenous Factor XIIf to activate the prekallikrein. Kallikreins I (Mr 91 000) and II (Mr 85 000) were purified 170- and 110-fold respectively. Kallikrein I was used for the kinetic work. PMID- 6921036 TI - The kinetics of hydrolysis of some extended N-aminoacyl-L-arginine methyl esters by porcine pancreatic kallikrein. A comparison with human plasma Kallikrein. AB - The effects of subsite interactions in the S2-S4 region [Schechter & Berger (1967) Biochem. Biophys. Res. Commun. 27, 157-162] of porcine pancreatic kallikrein (EC 3.4.21.8) on its catalytic efficiency have been investigated. Kinetic constants (Kcat, Km) have been determined for a series of seven extended N-aminoacyl-L-arginine methyl esters whose sequence is based on either the C terminal sequence of kallidin (-Pro-Phe-Arg) or (-Gly-)nArg. With these substrates it has been found that neither acylation nor deacylation of the enzyme is rate-limiting. Values of Kcat. range from 21.5 to 2320s-1, indicating that there are interactions with different residues in the N-aminoacyl chain and enzyme subsites in the S2-S4 region. It is shown that possible hydrogen-bonded interactions with the enzyme in the S3-S4 region have a significant effect on catalysis. The presence of L-phenylalanine at P2 has a very large effect on both Kcat, and Km, giving a greatly enhanced catalytic efficiency. Substrates with L proline at P3 also have a marked effect, but in this case the overall effect is one of lowered catalytic efficiency. By comparison with the results of a similar study with human plasma kallikrein I (EC 3.4.21.8), it has been possible to demonstrate that there are considerable differences in kinetic behaviour between the two enzymes. These are related to relative differences in the rates of acylation and deacylation with ester substrates and also the roles of subsites S2 and S3 of the two enzymes. PMID- 6921037 TI - Protocol management of CAPD complications. PMID- 6921038 TI - Early peritonitis in CAPD. PMID- 6921039 TI - Management of bloody dialysate. PMID- 6921041 TI - Management of the patient with juvenile onset diabetes mellitus (JODM) in end stage renal disease (ESRD) using a variety of dialysis therapies. PMID- 6921040 TI - Diabetic teaching of the CAPD patient. PMID- 6921042 TI - CAPD: are three exchanges per day adequate? PMID- 6921043 TI - Dietary management of infants on CAPD. PMID- 6921044 TI - Adaptation to home dialysis: the use of hemodialysis and peritoneal dialysis. PMID- 6921046 TI - Inhibition of human leucocyte elastase activity by cigarette smoke. PMID- 6921048 TI - I just saved your life. PMID- 6921049 TI - Nurse administrator - still a nurse. PMID- 6921045 TI - A comparison of home training and problems encountered with initial home dialysis: hemodialysis vs CAPD. PMID- 6921047 TI - Are lysophosphatidic acids or phosphatidic acids involved in stimulus activation coupling in platelets? PMID- 6921050 TI - A growing need for geriatric nursing. PMID- 6921052 TI - We must prove the value of quality care: keeping current, advancing in theory. PMID- 6921051 TI - Reward excellence in practice. PMID- 6921053 TI - You and the law. Are you listening, nurse? PMID- 6921054 TI - Good health is not the prerogative of the young. PMID- 6921055 TI - Understanding the sexual needs of the older patient. PMID- 6921056 TI - These family members are not alone. PMID- 6921057 TI - Alzheimer's disease: the silent epidemic. PMID- 6921058 TI - Home health care for seniors. PMID- 6921059 TI - Hospital equipment. PMID- 6921060 TI - What's happening in rehab nursing. PMID- 6921062 TI - Peripheral vascular disease: how to recognize it, how to treat it. PMID- 6921061 TI - Psychiatric assessment on a forensic unit. PMID- 6921063 TI - The best of two worlds: an appraising look at joint appointments in Canada today. PMID- 6921066 TI - An avenue for health care awareness. PMID- 6921064 TI - Couple-directed contraceptive counseling. PMID- 6921065 TI - What makes a "good" nurse? PMID- 6921067 TI - Alone at last. PMID- 6921068 TI - You and the law. Similar labels: tragic results. PMID- 6921069 TI - The sleeping giant. PMID- 6921070 TI - Caring to know...knowing to care. PMID- 6921073 TI - The use of social networks to help cancer patients maximize support. PMID- 6921072 TI - Head and neck cancer: our reactions. PMID- 6921071 TI - Implementing a program to control chronic pain of malignant disease for patients in an extended care facility. PMID- 6921074 TI - Classifying cancer client needs for community health nursing intervention. PMID- 6921075 TI - The management of the patient with breast cancer. PMID- 6921077 TI - Programmed instruction: cancer care. Cancer prevention: cancer risk factors. PMID- 6921076 TI - Cancer nursing and the law: the malpractice crisis--part II. PMID- 6921078 TI - Standards of clinical nursing practice: the side effects of chemotherapy in the treatment of leukemia. PMID- 6921079 TI - Pattern of isoaccepting transfer RNAs common to 26 patients with Hodgkin's disease. AB - The elution profiles of aminoacyl transfer RNAs from Hodgkin's tumors have been compared with the corresponding patterns from normal splenic tissue. Aminohexyl Sepharose and reversed-phase 5 chromatography have been used in the fractionation studies. Three peaks of acceptor activity have been observed in phenylalanyl, histidyl, aspartyl, and asparaginyl transfer RNAs. A second peak was shown in the case of tyrosyl and methionyl transfer RNAs. Seryl transfer RNA showed no change in elution profile; namely, a single species was observed in both normal and tumor transfer RNAs. These observations are confirmation that Hodgkin's disease is a malignant disease. The uniformity of the extra species of tRNA suggests that there is a commonly occurring aberration in the cell of origin of the Hodgkin's tumor. PMID- 6921080 TI - Meeting the emotional needs of survivors of sudden cardiac arrest. PMID- 6921082 TI - Competition: the new solution to health care costs? PMID- 6921081 TI - Effect of backrest position on pulmonary artery pressure in critically ill patients. PMID- 6921083 TI - "Psychosocial issues in nursing care of the elderly": annual W.L.N. program. PMID- 6921085 TI - [A view on American medical care - an experience as a member of patients' family]. PMID- 6921087 TI - [In search of the starting point in teaching nursing - encounters with the nursing theory in the past 10 years (10)]. PMID- 6921084 TI - A nursing doctorate in your future? PMID- 6921086 TI - [The meaning of nursing care to a man]. PMID- 6921089 TI - [Encounters with patients with senile dementia - an experience at the geriatric ward]. PMID- 6921088 TI - [To live - significance of the life and death in the modern man]. PMID- 6921090 TI - [Nursing and the life of patients - an experience of a nurse as a patient. (1)]. PMID- 6921091 TI - Who is responsible? PMID- 6921092 TI - Elimination: notes from a district nurse. PMID- 6921093 TI - Elimination: a time and a place. PMID- 6921094 TI - Critical care nursing: responsibilities beyond the unit. PMID- 6921096 TI - Administering emergency antidotes to the acutely poisoned patient. PMID- 6921095 TI - Patients' cardiac responses to nursing interviews in a CCU. PMID- 6921098 TI - Developmental care in the neonatal ICU. PMID- 6921097 TI - Small-town critical care. PMID- 6921099 TI - Rotational scheduling in the ICU. PMID- 6921100 TI - Teaching patients' families to provide ventilator care at home. PMID- 6921101 TI - A view from the foot: the role of podiatry. PMID- 6921102 TI - Diabetic foot infections. PMID- 6921103 TI - Appraisal of the diabetic patient. PMID- 6921104 TI - Psychosocial side of diabetes and its complications. PMID- 6921107 TI - Advice from the dieticians. Teaching slow learners. PMID- 6921105 TI - A study of diabetes educators in Ohio hospitals. PMID- 6921106 TI - A unique experience with self glucose monitoring. Patient profile. PMID- 6921108 TI - On the properties of immobilized elongation factor Tu from Thermus thermophilus HB8. AB - Elongation factor Tu from Thermus thermophilus was coupled to cyanogen-bromide activated Sepharose 4B and its properties were investigated. The immobilized elongation factor retained its ligand binding properties. It specifically binds GDP and GTP but does not interact with other nucleotide 5'-phosphates. A conversion of immobilized EF-Tu . GDP to EF-Tu . GTP can be achieved by simple equilibration with GTP. The immobilized EF-Tu . GTP specifically binds aminoacyl tRNAs and allows a facile purification of aminoacyl-tRNA species from bulk tRNA. It is stable at room temperature for several months and can be repeatedly used for aminoacyl-tRNA isolation. PMID- 6921110 TI - A comparison of urine specific gravity values in diaper vs. bagged specimens. PMID- 6921109 TI - A day in the life of... PMID- 6921111 TI - [Pregnancy, labour, and puerperium in heroin addicted women, with reference to experience and the present state of knowledge (author's transl)]. AB - The mounting problems of drug addiction now also confront the obstetrician and pediatrician. 1/3 of the 60,000 addicts to opiates in the Federal Republic of Germany are women. Of these 80% are in the reproductive age group. Despite endocrine problems pregnancies do occur and are high risk pregnancies because of hepatitis, venereal disease, malnutrition, phlebitis, abscesses, premature deliveries, premature rupture of the membranes, malpresentations, dysmaturity, pre-eclampsia, and numerous other social and psychological problems. Because of the varying content of heroin on the black market the fetus runs the risk of acute overdose or withdrawal. Withdrawal results in extremely marked fetal movements, with increased oxygen consumption and a danger of intra-uterine asphyxia sometimes resulting in intra-uterine fetal death. Most newborns develop a withdrawal syndrome with irritability, high pitched cries, shivering, tachycardia, perspirations, fever and generalized seizures. The experience of the Department for Women for the Free University in Berlin-Charlottenburg are presented and compared to a review of the literature. The medical, social, and psychological aspects of the problem are discussed. PMID- 6921113 TI - [Some critical remarks to rheobase-diagnosis (author's transl)]. PMID- 6921112 TI - [Effective employment of rubella-immunoglobulin (author's transl)]. AB - Rubella and its complications during pregnancy must be taken seriously, as 12-15% of german females being able to deliver are encountered without protective immunity. Depending on gestational age rate of malformation goes up to 60%. To prevent embryopathy general vaccination of the population is considered to be most effective. Application of rubella-immunoglobulin to seronegative expectant mothers is an emergency measure. Necessary are high dosage and rapid injection after suspicion of ambient rubella. The need for high dosage and rapid injection is based on results of clinical investigations, that have been carried out during the recent years. PMID- 6921114 TI - [Failures with the tubal ligation with the Bleier-secuclips (author's transl)]. PMID- 6921115 TI - [The treatment of benign lesions of the cervix by infrared coagulation (author's transl)]. AB - The infra-red coagulation is a new outpatient method for the treatment of benign changes in gynaecology. It causes little pain and is suitable for haemostasis at the cervix, in the vagina and in the vulva. The effect of this treatment is comparable to laser coagulation. An exact dosage of the coagulation energy is possible and therefore the depth of treatment and the surface of the treatment are known accurately. The side effects of the treatment are minimal, a fast and good healing of the coagulation area can be expected. The results of infra-red coagulation in 72 patients are presented. PMID- 6921116 TI - [Problems on early detection of the endometrial adenocarcinoma with a critical examination of jet-wash and curity-technique (author's transl)]. AB - The difficulties to find an appropriate screening-technique for the recognition of endometrial adenocarcinoma are described. Some methods of the last ten years are mentioned, advantages and disadvantages are shortly debated. Our clinical study contains 100 patients, who were examined by the jet-wash or curity-method with following abrasion. Practicability, security and the agreement of both techniques with histological results are compared. The most serious objection against jet-wash is the abdominal spreading of cells along the tubes. Curity screenings are yet carried on with good results. PMID- 6921117 TI - [Intracavitary radiotherapy of benign recurrent uterine bleedings (author's transl)]. AB - 387 patients with uterine bleeding resistant to other therapy were treated by intracavitary radium-therapy. In all cases there was a contraindication for the operative removal of the uterus. In 94,3% of our cases the bleeding could be treated successfully by the radium-application. Side effects of the irradiation occurred only in a minimal and neglectable percentage. Therefore the intrauterine contact-irradiation-therapy should be remembered in cases of uterine bleeding resistant to hormonal therapy or in cases of high risk for operation. With the new and modern afterloading device the molestation for the patients could be reduced to a minimum. PMID- 6921118 TI - [Preoperative radium insertion in the management of carcinoma of the endometrium (author's transl)]. PMID- 6921120 TI - [Urological investigation in women with stress incontinence prior and following anterior colporrhaphy and in control patients (author's transl)]. AB - The pre-operative and post-operative findings in 56 patients with urinary stress incontinence are compared amongst each other and with the result of 24 continent control patients. The 56 patients were selected prospectively. The urethral closure pressure with stress and the stress quotient in urethral cystometry are significantly improved by the operations. The compliance as a cystometric criterium was significantly raised. The sizes of the angle in the urethrocystogram are at times significantly changed after operation. They are not lower than the values described in the literature. This shows good correlation with the results in the control groups, which have angles higher than those described in the literature. The time parameters of the uroflowmetry show prolongation after the anterior colporrhaphy. The times to the maximum, the waiting time, the urine flow time and the duration of micturition are longer. The mean volume of urine per second is not significantly changed. Our results are compared with other investigations. The findings in healthy continent women are considered to be possible parameters for a reference. PMID- 6921119 TI - [Ultrasonographic diagnosis of vesicouterine fistula (author's transl)]. PMID- 6921121 TI - [Rubella embryopathy, still now? (author's transl)]. PMID- 6921123 TI - [The problem of domiciliary obstetric practice (author's transl)]. AB - From a group of 8,020 well-documented and electronically recorded deliveries at the Tubingen University Gynaecological Clinic during 1976-1979 we selected 1147 (14.3%) according to strict criteria and subjected them to further analysis. These 1147 pregnant women had one feature in common, namely, that there were absolutely no signs of any risk factor prior to delivery (Table 1). RESULT: 83% only of these children were delivered spontaneously; in 0.8% of the cases it was necessary to effect Caesarean section, and in another 15% vaginal-surgical delivery proved necessary. In 10% threatening and in 0.9% acute foetal asphyxia was the guiding sign for appropriate obstetric measures. In 31.4% of the cases we found a twisted cord, whereas the frequency rate of acidosis (pHNA less than 7100) was 7%. Apgar counts below 7 were seen in 2.3% and indices below 3 in 0.1% of the cases. Perinatal mortality was approximately 1:1000. Complications requiring follow-ups were seen in the first week post partum in every 20th child. It is concluded that domiciliary obstetric practice cannot be medically recommended since it involves a risk rate for both mother and child which is considered too high. PMID- 6921124 TI - [The value of a single determination of serum uric acid concentration in the early diagnosis of hypertensive disorders in pregnancy (author's transl)]. AB - In 200 healthy, normotensive nulliparous women, a single determination of serum uric acid concentration was done between weeks 28-32 of gestation in order to identify a possible increased risk of developing hypertensive complications. If serum concentrations higher than 3.6 mg/dl were considered as increased ("positive test"), women who developed toxaemia of late pregnancy (proteinuric hypertension), had a significantly elevated mean serum uric acid concentration already at the beginning of the third trimester (p less than 0.01). The incidence of toxaemia and hypertensive disease without proteinuria was significantly higher in the group of women with an elevated uric acid value (p less than 0.001). Only 9% of pregnant women with a "negative test" ultimately developed a mild form of a hypertensive complication. Conversely, 74% of the patients with a "positive test" remained normotensive. Thus, the predictive value of a "positive test" is low (26%) and that of a "negative test" relatively high (91%). PMID- 6921122 TI - [Unexpected risks during labour and delivery following a low risk pregnancy (author's transl)]. AB - Of the maternity patient of the Munich perinatal study from 1975-1977 54.4% were considered to be low risk at the end of the pregnancy. Of these every third patient (17%) developed at least one risk during labour and delivery. These were considered to be consequence risks if they and been present at the onset of labour and delivery or progress risks if they developed during labour and delivery. The progress risks were defined as unpredictable and occurred in 4.7% of the total study. In this group the incidence of spontaneous delivery was only 36.0% compared with 88.5% in the compare group. The perinatal mortality of 6.9% was three times higher than for women who remained low risk during labour and delivery. The commonest unpredictable risks are anomalies of presentation. Acidosis and pyrexia during labour and delivery and emergency risks occur most often in women who start labour and delivery with existing risks. For these so called progress risks with a high incidence of operative deliveries an operating room must be available at all times in the interest of mother and fetus. The monitoring of the fetus must also be available. Even following a low risk pregnancy monitoring and operation may become necessary. PMID- 6921125 TI - [Risks and prognosis for success of a pregnancy following replacement of a heart valve (author's transl)]. AB - After replacement of a heart valve a pregnancy is possible in the complaint categories I and II. Treatment with anti-coagulation is necessary for plastic heart valves. To avoid teratogenic effects the early pregnancy is best managed with heparin although stillbirth and early intra-uterine death are more common than with Marcumar. A treatment with heparin 10,000 units subcutaneously twice throughout all of the pregnancy is recommended. According to the literature 2/3 of the pregnancy with anti-coagulation result in the normal delivery of a healthy infant. Of 202 women in the reproductive age group with artificial heart valves, 150 were followed by a questionnaire. 25 women desired children. 10 women had pregnancies. 1 had two pregnancies, 1 had three pregnancies, 3 healthy infants were born. PMID- 6921126 TI - [Low birth weight is a negative factor in the mother-infant relationship. (A study of 122 women following primary Caesarean section for breech presentation or repeat Caesarean section.) (author's transl)]. AB - The mother-infant relationship was studied in the first days post-partum in 122 women following Caesarean section for breech presentation and following repeat Caesarean section. 1. Birth weight With low birth weights women had more rarely a good relationship to the infant in the early days post-partum. In only 20% of women with children under 3000 grams the early relationship was good compared to a good relationship in 61% with infants over 3500 grams birth weights. 2. Parity Less primiparae had good contact to the children in the first post-partum days (35%) than secondi and multiparae (54%). 3. Newborn care Women with difficulties to care for the newborn had good contact to the newborn in only 39% of the cases in the first post-partum days. Women without problems to care for the newborn had an early good relationship to the infant in 60% of the cases. 4. The personality of the mother Mothers with an intro-verted personality (according to MPI-E) and depressive tendencies (according to EDS) had significantly rarer close relationships to the newborn in the first post-partum days. According to these results the mother-infant relationship must be supported more vigorously in low birth weight infants not only in premature infants in the first days post-partum. Individual psychosocial factors must be taken into account which could make a satisfactory mother role more difficult. PMID- 6921127 TI - [The prognostic importance of the stage in patients operated for carcinoma of the endometrium (author's transl)]. AB - The operative specimens of 216 patients who underwent operation for adenocarcinoma of the endometrium stage I and stage II were thoroughly examined. It was found that measuring the maximal depth of infiltration of the carcinoma in relation to the thickness of the uterine wall and other morphological criteria of the tumours such as tumour grading, and carcinomatous lymphangiosis have greater prognostic value than clinical staging and the length of the uterine cavity to the sound. In contradistinction to other observations we found that patients with a short length of the uterus had more often recurrences and distant metastases than patients with a long uterine length to the sound. PMID- 6921128 TI - [CEA and the clinical course in advanced carcinoma of the uterine cervix (author's transl)]. AB - The clinical course of six representative patients suffering from advanced carcinoma of the uterine cervix and with elevated and borderline levels of CEA in serum prior to therapy is correlated in detail with the pattern of CEA in serum during and after therapy. It is shown that there is a close correlation between the serum CEA pattern and the course of the disease. Thus, serial CEA measurements in serum appear to be of value in the follow up of patients with carcinoma of the uterine cervix. PMID- 6921133 TI - Care of the acutely ill older adult. Transfer: nursing home to hospital. PMID- 6921130 TI - [Pretreatment of carcinoma in situ and microcarcinoma of the cervix by conization and endocoagulation (author's transl)]. AB - 65 microcarcinomas and 189 Ca. in situ-cases were diagnosed by cone biopsy in the Department of Gynaecology and Obstetrics of the University in Kiel in the periods 1973-1976 and 1977-1980. During the first period the haemostasis of the conization crater was obtained by the conventional techniques. In 38% (microcarcinoma) and 30% (Ca. in situ) of the cases the excised uterus was free of pathological epithelium. Since 1977 we have used simple coagulation of the wound area, with endocoagulation-technique according to Semm. In the second group (1977-1980), 73% (microcarcinoma) and 45% (Ca. in situ) were histologically normal, and only one case showed remaining microcarcinoma in the excised uterus. In individual cases--such as during pregnancy or where the patient still desires to have children--the Ca. in situ with not free margins, can be treated simply with a secondary coagulation of the wound crater. PMID- 6921131 TI - [Local testosterone treatment of lichen sclerosus of the vulva (author's transl)]. PMID- 6921132 TI - Care of the acutely ill older adult: Part one. Catastrophic illness: how it feels. PMID- 6921129 TI - [Directed colposcopic-cytologic diagnosis in cervical intraepithelial neoplasia (CIN) (author's transl)]. PMID- 6921134 TI - Care of the acutely ill older adult. Considerations in the physician's approach. PMID- 6921135 TI - Care of the acutely ill older adult. General nursing care. PMID- 6921139 TI - Drugs and the elderly. Precautions with hypnotics. PMID- 6921138 TI - Nutrition. Carbohydrate is not a villain. PMID- 6921136 TI - Dial C for caring. PMID- 6921140 TI - 70+ and going strong. Thoroughly independent Millicent. PMID- 6921141 TI - ACNM Convention 1982. PMID- 6921137 TI - Common concern. Food additives. PMID- 6921142 TI - Active-site labeling of rat and human urinary kallikrein by chloro(N alpha-p tosyllysyl)methane. AB - This is the first report to demonstrate that chloro(N alpha-p-tosyllysyl)methane (TosLys-CH2Cl) inhibits mammalian glandular kallikrein activities. The inhibitory effect of TosLysCH2Cl on purified rat urinary kallikrein was carried out with three assay methods: 1) Tos-Arg-OMe hydrolysis activity measured by a radiochemical method; 2) kininogenase activity using purified bovine low molecular weight kininogen as substrate and the released kinins subsequently measured by radioimmunoassay; 3) bioassay using isolated rat uterus preparation. Purified rat urinary kallikrein was inhibited by TolLysCH2Cl in a dose and time dependent manner with all three methods used. The inhibition of purified human urinary kallikrein esterase and kinin-releasing activities were also demonstrated. The results indicate that TosLysCH2Cl inactivates kallikrein activity and support the notion that reactive histidine residue(s) participates in the active center of Kallikrein for catalysis. PMID- 6921143 TI - On the various forms of the glandular kallikrein from autolyzed porcine pancreas. AB - Kallikrein C, a minor form of the glandular kallikrein isolated form autolyzed porcine pancreas, has the same amino acid composition a porcine pancreatic beta kallikreins A and B and comparable specific activity, but a much lower carbohydrate content. Dodecyl sulfate electrophoresis of the reduced enzyme indicated that it is composed of the same two polypeptide chains as the other pancreatic beta-kallikreins of the pig. The carbohydrate content of the two chains of beta-kallikrein B has been determined. Both the A and the B chain of beta-kallikreins from autolyzed porcine pancreas exist in a high-molecular (h) and a low-molecular (1) form which evidently differ only in their carbohydrate content. beta-Kallikrein B has the composition AhBh, beta-kallikrein A, AhB1, and beta-kallikrein C, A1B1. The properties of kallikrein III from porcine pancreas, recently described by Kira et al. (Adv. Exp. Med. Biol. 120A (1979) 273--290), indicate that is is the fourth conceivable form, A1Bh. A preparation of porcine pancreatic kallikrein d2 was found to have a specific activity comparable to that of other kallikrein preparations. Besides a main component migrating like pancreatic beta-kallikrein A, it also contained beta-kallikreins B and C. All four species of chains were observed to occur in this batch of the enzyme. Zuber and Sache (Biochemistry 13 (1974) 3098--3110) reported the resolution of porcine pancreatic kallikreins d1 and d2 into three electrophoretic components each after reduction. Evidently, all these preparations consist of a mixture of several forms of two-chain pancreatic beta-kallikrein. PMID- 6921146 TI - Cultural nursing: a point of view. PMID- 6921144 TI - Isolation of an enzymatically active tissue kallikrein from human seminal plasma by immunoaffinity chromatography. AB - A tissue kallikrein from human seminal plasma was isolated by immunoaffinity chromatography and characterized. Its molecular mass was determined by gel filtration to be approximately 40000 Da. The enzyme preparation liberates kinin from human HMW kininogen (specific activity: 0.594 HMW kininogen-U/mg), lowers the blood pressure of dogs after intravenous injection (specific activity: 1740 biol. kallikrein unit/mg) and is strongly inhibited by aprotinin but not by soybean trypsin inhibitor. N alpha-Acetyl-L-phenylalanyl-L-arginine ethyl ester, D-valyl-L-leucyl-L-agrine ethyl ester and N-benzyloxycarbonyl-L-tyrosine p nitrophenyl ester are cleaved with identical rates by the enzyme from human seminal plasma and human urinary kallikrein. PMID- 6921145 TI - Properdin factor B(Bf) polymorphism in tribal populations of Himachal Pradesh, India. PMID- 6921147 TI - Battered women: a health care problem in disguise. PMID- 6921148 TI - All the world's a stage ... even for nurses. PMID- 6921149 TI - Publishing opportunities for nurses: a comparison of 100 journals. PMID- 6921150 TI - Utilization of nursing research findings. PMID- 6921151 TI - Selecting a clinical nursing problem for research. PMID- 6921152 TI - Dissemination of nursing research findings. PMID- 6921154 TI - Steady state relations between control proteins regulating the formation of the alternative pathway C3 convertase. AB - A steady state algebraic Mass Action analysis of the factors controlling the concentration of the alternative pathway C3 convertase is presented. The positive feedback loop does not make this portion of the complement system insensitive to variation in control protein concentrations; on the contrary, a hyperbolic relationship is revealed between C3 convertase and a complex product of the control protein concentrations which contains some mathematical non-linearities. The consequences of this relationship are explored. It is found that variations in the concentration of any one control protein will have an effect which can only be predicted if its initial concentration and those of the other control proteins are known. The system is capable of responding with a considerable range of amplitudes to a given signal which raises the question as to whether the feedback loop confers biological advantage, not only by augmenting the activation of C3 to C3b, but through its potential for flexibility in responding to an activating stimulus. The analysis may also prove useful in the design and evaluation of experiments to determine the reaction rate constants governing the interactions between the control proteins in the fluid phase in vitro. PMID- 6921153 TI - The degradation of serum amyloid A protein by activated polymorphonuclear leucocytes: participation of granulocytic elastase. PMID- 6921155 TI - Effect of alterations in extracellular fluid volume on urinary kallikrein in the conscious rat. AB - The effect of alterations in extracellular fluid volume (ECV) and solute concentration on excretion of urinary kallikrein was examined in conscious Sprague-Dawley rats. Animals were given infusions of either dextrose and water, saline, or albumin according to a variety of protocols. These were designed to evaluate possible relationships between excretion of kallikrein, volume, sodium, and potassium. A reproducible pattern of kallikrein excretion was noted in all volume expanded groups. This consisted of a short lived increase during the initial hour of expansion with a subsequent fall to lower levels than baseline and a gradual recovery. To define the role of aldosterone in these studies, an adrenalectomized group and a group of appropriately prepared sham controls were expanded with saline. Adrenalectomy did not effect this pattern. We postulate a tubular "washout" phenomenon as the etiology of these observations. Results of these studies fail to demonstrate a consistent relationship between urinary volume, sodium, or potassium and the simultaneous amount of kallikrein found in the urine. PMID- 6921156 TI - [Agriculture and toxic hazards]. PMID- 6921157 TI - [Biology - contraception - adolescence. From the physiology of puberty to the possible physiopathology of contraception in the formative years]. PMID- 6921159 TI - [Mandatory examinations in children]. PMID- 6921158 TI - [Industrial nurse and occupational accidents (prevention and team work)]. PMID- 6921160 TI - [Digestive system disorders in diabetes]. PMID- 6921161 TI - [In government departments, school health services get organized]. PMID- 6921162 TI - [Biology--contraception--adolescence (part 2)]. PMID- 6921163 TI - [Caring to known...knowing to care]. PMID- 6921164 TI - [The newborn suffering from a labio-palatine fissure normally]. PMID- 6921165 TI - [Born with a cleft lip or cleft palate]. PMID- 6921167 TI - [Point-blank: it's very little 35 scholarships for emergency nursing]. PMID- 6921168 TI - [Legal aspects: when your patient wants to know]. PMID- 6921169 TI - [In a period of commotion, providing rigourous leadership]. PMID- 6921166 TI - [The significance of death in suicide]. PMID- 6921170 TI - [AIIC networks: our labor relations committee: first in line]. PMID- 6921171 TI - Evaluation of nursing care--could it make a difference? PMID- 6921172 TI - The Aberdeen Formula as an illustration of the difficulty of determining nursing requirements. PMID- 6921173 TI - Follow-up study of the Tel Aviv University nursing graduates. PMID- 6921174 TI - Nursing education in the Arabian Gulf: the Bahrain model. PMID- 6921175 TI - Cardiopulmonary resuscitation competencies of nurses. PMID- 6921176 TI - Regulation of renal hemodynamics. PMID- 6921177 TI - Bacterial meningitis. A follow-up study of 115 children. AB - The clinical and laboratory date on 115 pediatric patients with bacterial meningitis are presented. Sixty-one were less than 12 mo of age including 13 less than 1 mo of age. Thirty-nine children were treated prior to admission with antimicrobial agents which obscured accurate bacteriologic diagnosis in eight of them. Gram-negative enteric bacteria, mainly Escherichia coli, were recorded in 9 of 13 neonates. Hemophilus influenzae type B accounted for 56 (52%) of all isolated recorded in those greater than 2 mo of age, of which 35% were resistant to chloramphenicol. Seventy-eight patients (73%) recovered completely following 10 to 14 days of antimicrobial therapy. Fifteen patients died, most of whom were less than 1 yr of age, including five neonates. Major neurologic sequelae included subdural effusions, cerebral abscesses and recurrent convulsions. This study, which documents the infrequency of Streptococcus group B and H. influenzae as etiological agents of neonatal meningitis, indicates that treatment of this disease with ampicillin and an aminoglycoside is efficacious. Chloramphenicol may be the drug of choice in the postnatal period, since H. influenzae is partly resistant to ampicillin. PMID- 6921179 TI - The Sickle Cell Society. PMID- 6921178 TI - Sickle cell disease. PMID- 6921180 TI - Genetic counselling and the work of a medical genetics centre. PMID- 6921181 TI - Phenylketonuria--a problem in pregnancy. PMID- 6921182 TI - Know your organizations: the Myalgic Encephalomyelitis Association. PMID- 6921183 TI - Know your organizations: Tuberous Sclerosis Association. PMID- 6921184 TI - Health visiting and the elderly--a geriatrician's view. PMID- 6921185 TI - Running a pre-retirement course. PMID- 6921186 TI - President's message: the diagnosis and treatment of the ineffective nursing administrator. PMID- 6921187 TI - Normal fluctuations in pulmonary artery and pulmonary capillary wedge pressures in acutely ill patients. PMID- 6921188 TI - Bretylium tosylate--induced stabilization of electrical systole duration in patients with acute myocardial infarction. AB - The electrical systole duration (QTc), heart rate, and the QTc/QTt ratio were studied during the hospital course of an uncomplicated AMI in 13 patients treated with bretylium tosylate (10 mg/mg/24 hr over 5 days since confirmation of AMI) and in 19 controls. The QTc/QTt ratio showed prolongation of electrical systole duration in control subjects with a maximal value at the second day after AMI. QTc increased in these patients from day 1 to day 2 after AMI (402 +/- 4 msec vs. 430 +/- 3 msec, p less than 0.05) and decreased in the following days (p less than 0.05). During hospitalization cardiac rate was constant in both groups. In contrast, patients treated with bretylium tosylate showed a stable duration of QTc and the QTc/QTt ratio did not indicate prolongation of electrical systole duration. After drug discontinuation a slight increase in QTc duration was noticed (391 +/- 6 msec vs. 413 +/- 5 msec, p less than 0.05). These observations may contribute to the understanding of the antiarrhythmic action of bretylium and would indicate its usefullness in AMI patients with prolonged QTc and high risk of life-threatening arrhythmias. PMID- 6921189 TI - Use of the pulmonary arterial catheter in the critically ill patient. PMID- 6921190 TI - Cardiovascular drugs and the elderly population. PMID- 6921192 TI - Psychosocial and physiologic needs of patients with arterial occlusive disease during the preoperative phase of hospitalization. AB - This study explored the needs experienced by 60 patients with chronic AOD during the period of hospitalization preceding reconstructive surgery. Ten physiological, psychological, and sociocultural need variables were found to relate to two major needs, a need for information and a need for support. The investigator identified a need for information related to preventive health behaviors and a need for support related to four areas. The patients expressed a need for support to overcome difficulties experienced in coping with the ramifications of chronic illness and anxiety regarding future progression of the disease. Significant differences existed between male and female and older and younger patients in several need areas. Influencing factors were primarily associated with perceived changes in self-concept and role relationships. The study indicated that difficulties experienced in adapting to chronic vascular disease exert a major influence on patients' perceptions during the preoperative period. Intervention during this period must thus meet needs related to both the chronic nature and the acute surgical phase of the disease. The study has provided an initial basis for developing interventions to meet these needs. However, further research utilizing a multivariate approach, is necessary before the complex nature of factors influencing patients' needs will be understood totally. PMID- 6921191 TI - Effects of chronic lung disease on life in general and on sexuality: perceptions of adult patients. PMID- 6921193 TI - Psychological stress in spouses of patients with myocardial infarction. PMID- 6921194 TI - The effects of family/friend visits vs. staff interaction on stress/arousal of surgical intensive care patients. PMID- 6921195 TI - Tropical eosinophilia presenting as acute bronchial asthma: case report with clinical, physiologic, and histologic features before and after treatment. PMID- 6921196 TI - Anticholinesterase insecticide poisoning. AB - Anticholinesterase insecticides can be lethal, especially to small children. Prevention, not treatment, is the key to lowering the mortality rate. However, treatment, when necessary, can be effective if the poisoning agent is identified quickly as an anticholinesterase insecticide and therapy is begun immediately and aggressively. Large doses (up to 5 gm) of atropine, which block the parasympathetic effects of the poison, in conjunction with pralidoxime, a cholinesterase regenerator, need to be administered, second only in priority to establishing an airway. The second line of attack after adequate atropinization is supportive. Assistance with ventilation is individualized according to the degree of patient need. Intake with cautiously vigorous fluid therapy and output via Foley catheter are essential. Gastric lavage, seizure precautions and control as necessary, good body hygiene, and frequent turning are also part of necessary nursing intervention. Prognosis is fairly good if improvement is shown after therapy is begun. Maintaining adequate atropinization seems to be difficult yet essential to the success of the treatment and a good prognosis for the patient. PMID- 6921197 TI - [Memo concerning cardiotocography (CTG)]. PMID- 6921198 TI - [Report from an international symposium about advantages and risks of oral contraceptives. Amsterdam, March 1982]. PMID- 6921199 TI - Effect of diet on exocrine pancreatic insufficiency in dogs. AB - Clinically normal dogs and dogs with surgically induced exocrine pancreatic insufficiency were fed a dry dietary food (diet A) formulated for use in dogs with gastrointestinal disorders or a popular dry dog food (diet B). Feces from the dogs and the diets were analyzed for moisture and fat content. Dogs with surgically induced exocrine pancreatic insufficiency were studied with and without oral pancreatic enzyme treatment, which was supplemented with gastric acid modifiers. In the amounts fed, diet A provided 26% less dry matter and 18% less fat than did diet B; however, the fat content and dry matter in feces were approximately 60% less when dogs were fed diet A, compared with diet B. The digestibility of fat in normal dogs was similar for both diets. All other results indicated that feeding diet A versus diet B would result in improved assimilation of fat and dry matter in dogs with exocrine pancreatic insufficiency. PMID- 6921200 TI - Media factors affecting Augmentin disc sensitivity testing results. PMID- 6921201 TI - Ultrastructure of cobra venom factor-dependent C3/C5 convertase and its zymogen, factor B of human complement. AB - The molecular architecture of the cobra venom factor (CVF)-dependent C3/C5 convertase (EC 3.4.21.47) of human complement was deduced from electron microscopy of the purified bimolecular complex (CVF,Bb) and its isolated subunits, CVF and Bb. Negatively stained CVF imaged as an irregularly shaped cylindrical structure, with approximate dimensions of 137 A x 82 A (length x diameter). The zymogen Factor B appeared globular with a diameter of about 80 A and its image suggested a bipartite structure of two compact, closely associated regions, one about twice as large as the other. Bb, the larger, catalytic site bearing cleavage fragment of Factor B, revealed two globular domains, each 40 A in diameter, connected by a short linker region about 10 A long and thick. CVF and Bb could be distinguished in micrographs of the CVF,Bb complex: Bb attached to one end of the CVF molecule through only one of its two domains, and in an orientation making the long axes of both molecules approximately orthogonal. It is suggested the naturally occurring C3 convertases (C3b,Bb and C4b,2a) have a similar morphology. PMID- 6921202 TI - The effect of cations on the activity of human urinary kallikrein. AB - We studied the effect of ions on the ability of purified human urinary kallikrein to cleave its natural substrate (kininogen) as well as two synthetic substrates, tosylarginine [3H]methyl ester and Pro-Phe-Arg-[3H]benzylamide. The kininogenase activity of kallikrein is markedly dependent upon the concentration of cations in vitro. Kininogenase activity is very low when measured in a low electrolyte buffer. The addition of cations to the reaction mixture increases activity by up to 27-fold. Maximum activity is achieved with 100 mM sodium, 100 mM potassium, or 20 mM magnesium. The activity is stable at higher concentrations of cation. Renal kallikrein is believed to act within distal tubular fluid in vivo. The concentration of cations in this fluid varies widely in response to alterations in salt and water metabolism. Thus, the relationship of kininogenase activity to the concentration of cations demonstrated in vitro may be relevant to the activity of kallikrein at its presumed site of action in the kidney. In separate experiments, we evaluated the effect of ions on the amidase and esterase activities of kallikrein which are the basis of several assays in routine use for physiological studies. In contrast to their stimulatory effect on kininogenase activity, cations inhibit amidase and to a lesser extent esterase activity. Additional studies indicate that urinary cations probably account entirely for the well known ability of normal urine to inhibit the amidase and esterase activities of kallikrein. PMID- 6921204 TI - What does commitment to gerontological nursing really mean? PMID- 6921203 TI - Formation and structure of human Hageman factor fragments. AB - Autodigestion of activated Hageman factor (HFa) yields a 40,000-mol wt activated enzyme as well as Hageman factor fragment (HFf); HFf consists of two molecular weight species of 28,500 and 30,000. We have investigated the structure of these active fragments and demonstrate that upon reduction, each possesses a heavy chain of 28,000. The associated light chains were identified by subjecting iodinated proteins to two-dimensional slab gel electrophoresis in which the second dimension is run reduced. The 40,000-dalton enzyme has a light chain of 15,000, the 30,000-dalton form of HFf has a light chain of 2,000 and we have suggestive evidence of a light chain associated with the 28,500-dalton form of HFf (putative mol wt approximately 500). We also demonstrate that the 30,000 dalton form of HFf precedes the 28,500 form. These data indicate that digestion of native HF to form HFa precedes cleavages that fragment the molecule and diminish its molecular weight. The 28,500-dalton light chain of HFa becomes the heavy chain of each of the fragmentation products while cleavage at different points along the heavy chain of HFa determines which fragments will be produced. In contrast to autoactivation, kallikrein digestion of HFa yields primarily HFf; however, the 40,000-dalton enzyme may be seen when prekallikrein-deficient (Fletcher trait) plasma is activated. PMID- 6921205 TI - An outreach program for the urban elderly. PMID- 6921206 TI - Aging in perspective: the evolution of medical and social policy. PMID- 6921208 TI - Promoting activity: an approach to facilitating adaptation to aging changes. PMID- 6921207 TI - The director of nursing in the nursing home setting: an emerging dynamic role in gerontological nursing. PMID- 6921210 TI - Geriatric nursing: our specialty comes of age. PMID- 6921209 TI - Interview: Mary Opal Wolanin: gerontological nurse of the year. PMID- 6921211 TI - Movement, music, and remotivation with the regressed elderly. PMID- 6921212 TI - Implementing interdisciplinary team practice in home care of geriatric clients. PMID- 6921215 TI - The problem of financing the Social Security system. PMID- 6921213 TI - Assessing an environment for safety first. PMID- 6921214 TI - The preventive health history form: a questionnaire for use with older patient populations. PMID- 6921216 TI - A new screening test for C3 nephritis factor based on a stable cell bound convertase on sheep erythrocytes. AB - C3 nephritis factor (C3nef) activity was measured by the incubation of sheep erythrocytes with a mixture of normal human serum and patient's serum in EGTA followed by lysis of the washed cells with rat C in EDTA. The C convertase activity on the cells was dependent on the dose of patient's serum. Activation of human C3-C9 by the washed cells was shown by lysis of susceptible target cells (chicken erythrocytes). The test is specific for C3nef. PMID- 6921217 TI - Brain injury and the family. PMID- 6921218 TI - Acoustic neuroma: an overview of the disorder and nursing care for these patients. PMID- 6921219 TI - Outcome following closed head injury. PMID- 6921220 TI - Planned periods of rest in the intensive care unit: nursing care activities and intracranial pressure. PMID- 6921221 TI - Update: head injuries. PMID- 6921222 TI - Significance of intracranial pressure waveform. PMID- 6921223 TI - Intraspinal cholesteatoma. PMID- 6921224 TI - How can I reassure my patient if I've never been in surgery? PMID- 6921225 TI - Families and feelings: a time for sharing. PMID- 6921228 TI - Big hat, no cattle: managing human resources, Part 1. PMID- 6921227 TI - Variance analysis: a tool for cost control. PMID- 6921229 TI - Assisting nurses toward professional growth: a career development model. PMID- 6921226 TI - Direct patient care: a viable career choice? PMID- 6921230 TI - Job analysis: the basis of effective appraisal. PMID- 6921231 TI - The client-consultant relationship--guidelines for the nursing administrator. PMID- 6921232 TI - Clarifying autonomy and accountability in nursing service: part I. PMID- 6921234 TI - Rational decision making: managing uncertainty. PMID- 6921233 TI - A clinical ladder? Maybe. PMID- 6921236 TI - Big hat, no cattle: managing human resources, Part 2. PMID- 6921235 TI - Dialogue in print: relating nursing staff quality to patients' needs. PMID- 6921239 TI - Relationships between professions: from the viewpoint of the physician and nurse midwife in a tertiary center. PMID- 6921238 TI - Fifty years of nurse-midwifery education reflections and perspectives. PMID- 6921237 TI - Educators, employees, and new graduates define essential skills for baccalaureate graduates. PMID- 6921244 TI - The benefits of breast-feeding. PMID- 6921240 TI - The umbilical cord: transcultural care and customs. PMID- 6921242 TI - Organizing a fund-raising event. PMID- 6921241 TI - Childbirth preparation: an important service for all. I. A research perspective. PMID- 6921245 TI - Psychosocial needs and the geriatric patient. PMID- 6921246 TI - Creating order out of CHAOS: coping with the pressures of hospital nursing. PMID- 6921247 TI - Diuretics--Part III. Thiazides. PMID- 6921248 TI - Compliance with lithium regimens. PMID- 6921243 TI - Calcium efflux from the rat neurohypophysis. AB - 1. Calcium efflux from isolated rat neurophypophyses has been studied. Curve fitting of the wash-out curves suggests three phases with t((1/2)) of ca. 3, 15 and 130 min.2. The slow component of the (45)Ca efflux is attributed to efflux of intracellular Ca. On the basis of the temperature sensitivity of the Ca efflux, the activation energy has been calculated to be approximately 12,000 cal/mole, corresponding to a Q(10) of ca. 2.0.3. Ca efflux decreased by approximately 32% when external Na was replaced by choline. Li(o), in the presence or absence of Ca(o), was as effective as Na(o) in stimulating the Ca efflux.4. The curve relating Ca efflux to [Na](o) or [Li](o) is sigmoid and suggests that at least two Na (or Li) ions are necessary to activate the efflux of each Ca ion. Ca(o) does not modify the absolute Na-dependent Ca efflux but decreases the affinity for Na of the site involved in Ca extrusion.5. Removal of Ca(o) decreased the Ca efflux by ca. 44% in Na-free media. The apparent affinity for Ca(o) of the Ca(o) activated Ca efflux (K(m) (Cao) = 20 muM) is greatly decreased by the presence of 150 mM-Na (K(m) (Cao) = 0.8 mM).6. Lanthanum decreased the total Ca efflux by ca. 60% and totally abolished the Na(o)-activated and Ca(o)-activated Ca efflux.7. Vanadate reduced the Ca efflux remaining in Na-, Ca-free saline by 73%.8. Elevation of Na(i) with ouabain did not modify the rate of loss of (45)Ca.9. Increased concentration of K(o) stimulated transiently the (45)Ca loss. The time course of this increase depends on the Ca(o) concentration ([Ca](o)).10. Cyanide or CCCP (carbonyl cyanide m-chlorophenylhydrazone) increased transiently the Ca efflux. The increase induced by cyanide could only be observed when the neural lobes had been over-loaded with (45)Ca.11. Membrane destruction induced by high temperature eliminated the effect of [Na](o) and [Ca](o) on (45)Ca efflux.12. In 150 mM-Na-containing saline, half-maximum activation of (45)Ca uptake occurs in the 0.2-0.4 mM [Ca](o) range.13. The Ca efflux from isolated pituicytes was not affected by removal of Na(o).14. In conclusion we show that Ca efflux from neurosecretory nerve terminals can be subdivided into three components of approximately the same magnitude, one which is activated by Na(o), another by Ca(o) and a third component which is independent of Na(o) and Ca(o). PMID- 6921249 TI - Family therapy for the single-parent family system. PMID- 6921252 TI - Medication education for patients in a partial hospitalization program. PMID- 6921251 TI - Grief associated with a prison experience: counseling the client. AB - With our constantly overcrowded prisons taxing the efforts of all helping personnel and increasing the already high rates of recidivism, perhaps it would benefit counselors and nurses to look to the adjustment process of new inmates as a field of endeavor. Facilitating the adjustment process might enhance the movement of a costly, dependent ward of the state to a contributing member of society. And what better time than during the initial crisis state of newly admitted offenders to intervene and, hopefully, help them through their "grief work," help them deal with their losses when their needs are so great and when they are deprived of previous negative influences. Maureen Chaisson (1981) says that the correctional institution is the last frontier for the health care system and states that the biggest single question in corrections today is, "How do we provide mental health services?" (Chaisson, 1981, p. 736). The newly admitted inmate, as demonstrated here, is in a state of crisis and is suffering grief and experiencing losses not unlike those traditionally ministered to by nurses. Providing the needed counseling and helping the client through his "grief work" might demonstrate to that inmate new ways of dealing with feelings and situations that perhaps contributed to his incarceration. If the offender is supported initially, perhaps adjustment might be smoother, frustrations minimized, and eventual return to society characterized by a higher level of functioning. At the very least, the offender who is suffering loss is entitled to health care by the Bill of Rights. This health care includes mental health services--and counseling the client through the initial grief is certainly a good place to begin. PMID- 6921250 TI - Prospective adolescent fathers: stresses during pregnancy and implications for nursing interventions. PMID- 6921253 TI - Microwave and RF hazard standard considerations. AB - This article present considerations which pertain to the limits of safe exposure of man to radio frequency and microwave frequency electromagnetic irradiation. Early considerations for the rationale of a 10 mW/cm2 standard and more recent results are summarized. The total frequency range can be conveniently subdivided into four parts: the below resonance range, the resonance range, the 'hot spot' range, and the surface heating range. They are discussed in subsequent sections. Finally, the topics of tolerable heat load, partial body irradiation and short time exposure are dealt with. The conclusions are in essential agreement with a proposed revision of the ANSI C95 standard. PMID- 6921254 TI - The development of microwave power applications in China. PMID- 6921255 TI - Error sources affecting thermocouple thermometry in RF electromagnetic fields. AB - Thermocouple thermometry errors in radiofrequency (typically 13, 56 MHZ) electromagnetic fields such as are encountered in hyperthermia are described. RF currents capacitatively or inductively coupled into the thermocouple-detector circuit produce errors which are a combination of interference, i.e., 'pick-up' error, and genuine rf induced temperature changes at the junction of the thermocouple. The former can be eliminated by adequate filtering and shielding; the latter is due to (a) junction current heating in which the generally unequal resistances of the thermocouple wires cause a net current flow from the higher to the lower resistance wire across the junction, (b) heating in the surrounding resistive material (tissue in hyperthermia), and (c) eddy current heating of the thermocouple wires in the oscillating magnetic field. Low frequency theories are used to estimate these errors under given operating conditions and relevant experiments demonstrating these effects and precautions necessary to minimize the errors are described. It is shown that at 13.56 MHz and voltage levels below 100 V rms these errors do not exceed 0.1 degrees C if the precautions are observed and thermocouples with adequate insulation (e.g., Bailey IT-18) are used. Results of this study are being currently used in our clinical work with good success. PMID- 6921256 TI - Care of retinoblastoma patients and their families. PMID- 6921259 TI - From a technical point of view: CPR update. PMID- 6921257 TI - Self-care agency in diabetic ocular sequelae. PMID- 6921258 TI - Rethinking the refitting of rigid contact lenses. PMID- 6921260 TI - Fundamentals in focus. Ocular emergencies. PMID- 6921262 TI - Handling ophthalmic epidemics: with a focus on acute hemorrhagic conjunctivitis. PMID- 6921261 TI - Perspective on contact lenses. PMID- 6921263 TI - LVN graduate address. PMID- 6921264 TI - Care of the elderly in Hungary. PMID- 6921265 TI - Name, address, insurance number - please! PMID- 6921266 TI - Facilitating healing. PMID- 6921267 TI - A time to do nothing. PMID- 6921268 TI - I don't want to join a union but. PMID- 6921269 TI - Socio economic power: the role of the professional organization. PMID- 6921270 TI - Age of consent to surgical, medical or dental treatment. PMID- 6921272 TI - [Determination of prekallikrein in human plasma by kaolin adsorption method (author's transl)]. PMID- 6921273 TI - [Radioimmunoassay of rat pancreatic elastase (author's transl)]. PMID- 6921271 TI - Nursing for a new century: a future framework. PMID- 6921274 TI - [Volunteer activities to protect women's health: a discussion with Ms. M. Wiesenthal, director of the American Cancer Society]. PMID- 6921275 TI - [Care and assistance during delivery in a sitting position]. PMID- 6921276 TI - [Sex education of pregnant women and its relationship with their knowledge and attitude to sex]. PMID- 6921277 TI - [Report on patients hospitalized with placenta previa in the past 5 years]. PMID- 6921278 TI - [Shower bath 24 hours after delivery]. PMID- 6921280 TI - [Methods in research surveys. 6. Characteristics of data and data collection]. PMID- 6921281 TI - [Past and present of birth customs. 6. Handling of the afterbirth as part of the infant]. PMID- 6921279 TI - [Status of family planning among the patients visiting our clinic]. PMID- 6921283 TI - [Observation and therapy of aphasia]. PMID- 6921282 TI - [Medical scope. Mechanism of labor induction. 1]. PMID- 6921284 TI - [Keypoints in the care of aphasic patients]. PMID- 6921285 TI - [Approach to aphasic patients: relationship between speech therapy and nursing: a discussion]. PMID- 6921287 TI - [Challenge in rehabilitation: a diary of an aphasic patient]. PMID- 6921288 TI - [Approach to aphasic patients: on a "speech drama"]. PMID- 6921286 TI - [Social rehabilitation of aphasic patients]. PMID- 6921290 TI - [A student's fist experience with a patient with poor prognosis - a lesson in nursing]. PMID- 6921289 TI - [The role of the family in the approach to a patient with total aphasia: cooperation of the speech therapist and nurses]. PMID- 6921291 TI - [Postmortem in nursing care]. PMID- 6921292 TI - [Clinical aspects of adolescence. I. Definition of adolescence]. PMID- 6921293 TI - [Physiology and hygiene of smoking. 10. Smoking women (1). Lung cancer and ischemic heart disease among the young generation]. PMID- 6921296 TI - [Profile of a nurse: Ms. Tomeyo Ogawa, a counsellor at an outpatient rehabilitation center]. PMID- 6921294 TI - [Oral (dental) diseases. 2. Dental caries]. PMID- 6921295 TI - [Transactional analysis in nursing. 12. Analysis of the "life script"]. PMID- 6921297 TI - [Aging report: geriatric care in England. 5. Victoria Hospital]. PMID- 6921298 TI - [Unforgettable life in Malawi, 5. Observation is important (1)]. PMID- 6921299 TI - [The relationship between volunteer activities and medical care]. PMID- 6921302 TI - [Volunteer activities: interactions with Mrs. O. who cares for her husband with Parkinson's disease]. PMID- 6921300 TI - [Nursing volunteers and community care: activities of Kobe University nursing volunteers in the past 13 years]. PMID- 6921301 TI - [Volunteer activities: interactions with Mrs. K with amyotrophic lateral sclerosis]. PMID- 6921303 TI - [Volunteer activities: memories of Mr. M., an aged diabetic man who lived alone]. PMID- 6921304 TI - [Volunteer activities as the lifework of the retired]. PMID- 6921305 TI - [Bedside nursing. Coping with the fear of death together with the terminal patient]. PMID- 6921307 TI - [Acceptance of death in a family environment and nursing care]. PMID- 6921306 TI - [Interview with Ms. Masako Ueda: 26 years of nursing at Nagashima Aisei-en]. PMID- 6921308 TI - [Clinical aspects of adolescence. 2. Psychological characteristics of adolescence. 1]. PMID- 6921309 TI - [Oral (dental) diseases: questions and answers. 3. Children and dental caries]. PMID- 6921310 TI - [Transactional analysis in nursing. 13. Decision making in changing goals in life]. PMID- 6921311 TI - [Profile of a nurse. Ms. Toshiyo Kushima who has devoted 30 years to urology nursing]. PMID- 6921312 TI - [Aging report: geriatric nursing in England. 6. Geriatric departments in various parts of England. 2. Edinburgh and Newcastle]. PMID- 6921313 TI - [Life in Malawi. 6. Observation is important. 2]. PMID- 6921314 TI - [Diagnosis of oral cancer--problems concerning early discovery and diagnosis]. PMID- 6921315 TI - [Clinical presentation of oral cancer]. PMID- 6921316 TI - [Combination and special therapy of oral cancer--care of the patient during therapy]. PMID- 6921317 TI - [Clinical nursing of patients with oral cancer--the nursing standards at the hospital attached to the Department of Dentistry, Tokyo Medical and Dental University]. PMID- 6921318 TI - [Instruction for oral hygiene for patients with maxillary cancer--evaluation based on surveys and bacteriologic examinations]. PMID- 6921320 TI - [Nursing of patients with cancer of the tongue--unilateral resection of the tongue and its reconstruction using an M-C flap: case report]. PMID- 6921319 TI - [Postoperative speech disturbances in patients with oral cancer and their treatment]. PMID- 6921323 TI - [Nursing of patients with maxillary cancer--nursing of a patient with few complaints]. PMID- 6921322 TI - [Mealtime assistance of a patient with mastication and deglution difficulties]. PMID- 6921321 TI - [Nursing of a patient with a large defect of the tongue due to extensive surgery of tongue cancer--with special reference to expression of the patient's desire]. PMID- 6921324 TI - [Conference. Mealtime problems and assistance of patients with oral cancer]. PMID- 6921325 TI - [Opportunistic infection]. PMID- 6921326 TI - [Auscultation]. PMID- 6921327 TI - [Auscultation at bedside and nursing planning]. PMID- 6921328 TI - Nursing consideration in formulating a care plan: a case study. PMID- 6921329 TI - [Improvement of self control of diabetic patients--analysis of the interveiws of outpatients]. PMID- 6921330 TI - [Rehabilitation in myocardial infarction. (2). Application of exercise therapy]. PMID- 6921331 TI - [Cataracts in children--treatment]. PMID- 6921332 TI - [Keypoints in pre- and postoperative care of cataract patients]. PMID- 6921333 TI - [Rehabilitation of aged patients following cataract surgery]. PMID- 6921334 TI - [Nursing of an aged patient with retinal detachment of the aphakic eye following cataract surgery]. PMID- 6921335 TI - [Approach to a patient with unsatisfactory recovery of vision after cataract surgery]. PMID- 6921336 TI - [Nursing of a patient with diabetic cataract--with special reference to health instruction at the time of discharge]. PMID- 6921337 TI - [Nursing of patients with traumatic cataracts]. PMID- 6921338 TI - [Nursing of children with congenital cataracts]. PMID- 6921339 TI - [Conference: determination of the extent of comprehension by the aged patients- on instruction on forced bedrest after cataract surgery]. PMID- 6921340 TI - [Stormy course and rehabilitation of a patient with ileostomy]. PMID- 6921341 TI - [Effect of the elbow angle on the pressure exerted in closed chest heart massage]. PMID- 6921342 TI - [Psychiatric approach to a psychiatric patient with undue concern for trivia of social interactions--a process leading to improvement in behavior after one year of hospitalization]. PMID- 6921343 TI - [Nursing diagnosis. Diagnosis of the skin. (I). Observation of the skin]. PMID- 6921344 TI - [Understanding skin changes in nursing diagnosis]. PMID- 6921345 TI - [Nursing of patients undergoing blind biopsy of the liver]. PMID- 6921346 TI - [Nursing diagnosis: making a concept come alive]. PMID- 6921348 TI - [Program adherence and patient education]. PMID- 6921347 TI - [Capacity for self control by diabetic patients and its relationship with nursing (1)--care of diabetic outpatients at Hyogo Medical College Hospital]. PMID- 6921350 TI - [Physiopathology of cataracts]. PMID- 6921349 TI - [Mechanism of cataract development]. PMID- 6921351 TI - [Artificial lenses]. PMID- 6921352 TI - [The hands and the eyes of the nurse: actions and observation in nursing]. PMID- 6921354 TI - [Nursing duty and the computer: current application of the computer in clinical nursing]. PMID- 6921353 TI - [Education in information sciences. Do not be afraid of the computer (I). A discussion]. PMID- 6921355 TI - [Training in information science at the PL Gakuen School of Hygiene and Nursing]. PMID- 6921356 TI - [The current status and future of the information system in a hospital ward]. PMID- 6921357 TI - [Interactions of medicine and nursing in the 80's]. PMID- 6921359 TI - [In search of educational humanity. (5) Dissolution of ego and formation of self]. PMID- 6921358 TI - [Approach in comprehension of the total personality of the patient (4)]. PMID- 6921360 TI - [Future problems in nursing education]. PMID- 6921361 TI - [On hospice movements. (1)]. PMID- 6921363 TI - [Do not be afraid of the computer. (2). A discussion]. PMID- 6921362 TI - [Approach in comprehending the total personality of the patient (5)]. PMID- 6921365 TI - [Achievements by an organization for handicapped children. Contribution of volunteer public health nurses: handicapped children and public health nurses in the Kariya area, Aichi Prefecture]. PMID- 6921364 TI - [In search of educational humanity (6). The theory of teaching. 1]. PMID- 6921366 TI - [Achievement of an organization for handicapped children: volunteer activities]. PMID- 6921367 TI - Activities of an organization for handicapped children: contributions by the personnel, volunteers and parents. PMID- 6921368 TI - [Public health nursing and a volunteer organization for handicapped children]. PMID- 6921369 TI - [Home nursing technology. Care involved in excretion. (3)]. PMID- 6921370 TI - [Public health nursing activities at Rokugo-mura, Gunma Prefecture]. PMID- 6921371 TI - [National health services in Scotland and Denmark (9). A visit to Denmark]. PMID- 6921372 TI - [Public health nursing with a focus on individual patients: care of patients with pneumoconiosis (1)]. PMID- 6921373 TI - [Incorporation of basic nursing and public health nursing education--on training in public health nursing theories]. PMID- 6921374 TI - [Geriatric activities at the Chigasaki Public Health Clinic--an outing for the bedridden elders to the seashore]. PMID- 6921375 TI - [Problems and directions in public health nursing: on the significance of being a member of the public health care team]. PMID- 6921377 TI - [Collective approach in public health nursing in the service to citizens: through an example in a public health nursing team at the Sayama Public Health Clinic]. PMID- 6921376 TI - [Role and functions of the chief public health nurse: a suggestion on the evaluation of the duties of the chief nurse]. PMID- 6921379 TI - [Personal history of a public health nurse in Gunma Prefecture. 4]. PMID- 6921380 TI - [Assistance in a crisis situation at a local level--application of the crisis theory]. PMID- 6921381 TI - [The spirit of Kainuu]. PMID- 6921382 TI - [Causes of mental deficiency from the viewpoint of the maternity care worker]. PMID- 6921383 TI - [Terminal care]. PMID- 6921378 TI - [Effects of pre-convinced ideas in evaluation of the subject: complication of a health survey of 3-year-olds]. PMID- 6921384 TI - [Childbirth in the sitting position]. PMID- 6921386 TI - Primary health care--implications for nursing education/services. PMID- 6921387 TI - Malaria. PMID- 6921385 TI - Setting the pace: new approaches in nursing practice: paper presented to the International Council of Nurses Congress at the 17th ICN Quadrennial Congress held in Los Angeles in June, 1981. PMID- 6921388 TI - The role of the nurse in community health services: a Kenyan picture. PMID- 6921389 TI - Sexually transmitted diseases are on the increase: where do we fit in as members of the health team? PMID- 6921390 TI - Presidential address of ICN's 17th quadrennial congress in Los Angeles. PMID- 6921391 TI - Opening speech for National Nurses Association of Kenya at School of nursing- Kenyatta. PMID- 6921392 TI - [Methods of nursing rotation]. PMID- 6921393 TI - [Nursing specialties and the rotation system: an example in the United States]. PMID- 6921394 TI - [Nursing rotation - personal experiences]. PMID- 6921395 TI - [Japanese view on the life and death - expectation on the modern nursing personnel (1)]. PMID- 6921396 TI - [Need for nursing rotation]. PMID- 6921397 TI - [Research in nursing. Toward a science of health care]. PMID- 6921398 TI - [Improvement of imagination and appreciation of literature - a study of short poems by Takuboku]. PMID- 6921399 TI - [Diary of a home-visiting nurse. 13]. PMID- 6921400 TI - [Happy mothers and babies: a report from a child care counseling service]. PMID- 6921401 TI - [Profile of a nurse. Mrs. Kazuko Nakayama, a nurse and a new mother of quadruplets]. PMID- 6921402 TI - [Medical topics. Lung cancer among employees of abattoirs]. PMID- 6921403 TI - [Medical topics. Tampons and toxic shock]. PMID- 6921404 TI - [Statistical file. Utilization of retired public health nurses in the legislative plan for the aged welfare]. PMID- 6921405 TI - [Nursing in the European Community: nursing directives in relation to other health-related professions: the role of nursing and its future]. PMID- 6921406 TI - [Social status of nurses in the modern history of nursing in Japan. 26]. PMID- 6921407 TI - [Statistical file. Statistics on facilities for nursing education run by various organizations]. PMID- 6921408 TI - [Disease, ill health, hospitalization and irritation of the patient]. PMID- 6921409 TI - [Causes for irritation of patients and solutions to the problems]. PMID- 6921411 TI - [Irritation of the patient caused by nurses]. PMID- 6921410 TI - [Japanese philosophy of life and death--expectation of the nursing personnel]. PMID- 6921413 TI - [Systematic nursing: a nursing process used in the actual nursing setting]. PMID- 6921412 TI - [Analysis of the contents of the medical record accompanying the patient at transfer to another ward. 3. Preparation of a standard form]. PMID- 6921414 TI - [Contented mothers and infants. 3. A report from the clinical scenes of infant care]. PMID- 6921415 TI - [Diary of a home care nurse]. PMID- 6921417 TI - [Medical topics. Carcinogenic potential of a dye used in the bait for finishing]. PMID- 6921416 TI - [A face in nursing: Mrs. Michiko Hibino who retired from a nursing school and made a new start in nursing education in Thailand]. PMID- 6921419 TI - [Medical topics. Magnetocardiogram]. PMID- 6921420 TI - [My leadership theory in nursing]. PMID- 6921418 TI - [Human milk, eczema, and asthma]. PMID- 6921422 TI - Nurse anthropologist as humanist-in-residence. PMID- 6921421 TI - Being a move coordinator wasn't in my job description. PMID- 6921423 TI - Survey of psychiatric nursing in Kansas. PMID- 6921424 TI - Analysis of continuing education providers' self-assessment of ability to meet KSBN provider requirements. PMID- 6921425 TI - Sunset of the state board of nursing--what is it all about? - What can you do? PMID- 6921426 TI - [Clinical and experimental study of the effect of obsidan and hemiton on the blood kallikrein-kinin system]. AB - In 52 patients with labile hypertension and also in experimental hypertension in 52 rats dynamics of kallikrein-kinin system in the blood during obsidan and hemiton treatment has been studied to find relationship between the hypotensive action of these drugs and the blood kinins activity. It was found that there exist counter-directional shifts in the kallikrein-kinin system of the blood as a result of treatment depending on their initial level. Adequate therapy contributed to the maintenance of optimum kinin concentration for preservation of homeostasis. With hypertensive syndrome supervening in rats increase of kinin predecessor synthesis has been recorded. Chronic administration of obsidan (0.5 mg/kg) and hemiton (0.1 mg/kg for 20 days increased kininogenesis). PMID- 6921427 TI - [Status of the head nurse in regard to hospital organization theory]. PMID- 6921428 TI - [Roles of the head nurse and supervisor]. PMID- 6921429 TI - [Study on the size of the areas under the control of a head nurse-- optimum size of each nursing unit]. PMID- 6921430 TI - [Functions of the nursing supervisor in changing nursing systems]. PMID- 6921432 TI - [New clinical images of man (6). Psychological development and interactions. A discussion]. PMID- 6921431 TI - [Keypoints in personnel administration concerning head nurses]. PMID- 6921433 TI - [Preparation of a nursing schedule using a computer]. PMID- 6921434 TI - [Nursing administration research at Toranomon Hospital. 5. Implementation of a patient classification system. I]. PMID- 6921435 TI - [Importance and problems in clinical training in the program of basic nursing education--an analysis of the process of learning nursing observation technics]. PMID- 6921436 TI - [Suggestion on introduction of programmed learning. (3). An example in preparation of a program on "assisting a patient in the use of a bedpan"]. PMID- 6921437 TI - [Changing attitudes of nursing students before and after clinical training-with special reference to their attitude to the training, image of the nurse, professional knowledge, and technics]. PMID- 6921438 TI - [Education of psychiatric nursing in the School of Nursing at the University of Hawaii: the position, program, and the relationship between classroom teaching and clinical training in psychiatric nursing education. Interview by M. Kawano]. PMID- 6921439 TI - [Nursing process/nursing of patients with liver cirrhosis. Physiopathology of liver cirrhosis]. PMID- 6921442 TI - [Nursing process/nursing of patients with liver cirrhosis. Nursing of a patient in a compensatory stage of liver cirrhosis. Case report]. PMID- 6921441 TI - [Nursing process/nursing of patients with liver cirrhosis. Nursing process for patients with liver cirrhosis]. PMID- 6921440 TI - [Nursing process/nursing of patients with liver cirrhosis. Diagnosis and treatment of liver cirrhosis]. PMID- 6921445 TI - [Introspection--through the experience with sensitivity training]. PMID- 6921444 TI - [Bedside examination keypoints in nursing and interpretation of the test data. Examination of the circulatory system (2): types of cardiac examinations and the examination processes]. PMID- 6921446 TI - [Use of the family bath for babies]. PMID- 6921448 TI - [Surgery--basis and practice. Open heart surgery (2). Pre- and postoperative nursing of patients undergoing heart valve replacement]. PMID- 6921443 TI - [Nursing process/nursing of patients with liver cirrhosis. Evaluation of the nursing process. A discussion]. PMID- 6921447 TI - [Surgery--basis and practice. Open heart surgery (2). Acquired heart diseases: surgical methods and keypoints in postoperative care]. PMID- 6921449 TI - [Surgery--basis and practice. Open heart surgery (2). Pre- and postoperative nursing of an aged patient with combined valvular disease]. PMID- 6921451 TI - [In search of a new nursing philosophy. XX. Assistance in setting a goal in life- a question on the nursing approach through a case study]. PMID- 6921450 TI - [Re-affirmation of the importance of understanding patients' background in a case study--a thought on three scenes involving an aphasic patient]. PMID- 6921452 TI - [The New Year's Day in Afghanistan]. PMID- 6921454 TI - [Nursing process/nursing of patients with breast cancer. Diagnosis and treatment of breast cancer]. PMID- 6921455 TI - [Nursing process/nursing of patients with breast cancer. Nursing process for patients with breast cancer]. PMID- 6921453 TI - [Nursing process/nursing of patients with breast cancer. Physiopathology of breast cancer]. PMID- 6921457 TI - [Nursing process/nursing of patients with breast cancer. Evaluation of the nursing process. A discussion]. PMID- 6921460 TI - [Assistance in motivating a patient with motor aphasia toward rehabilitation]. PMID- 6921458 TI - [Bedside examination: keypoints in nursing and interpretation of the test data. Urologic examinations: kidney function tests and urinalysis]. PMID- 6921459 TI - [Nursing processes: possibilities and limitations in their application. (9). Procedural evaluation of each step: practice and evaluation]. PMID- 6921456 TI - [Nursing process/nursing of patients with breast cancer. Nursing of a patient with breast cancer. A case study]. PMID- 6921461 TI - [A thought on the patient, his family, and the nursing personnel through an observation of a case]. PMID- 6921462 TI - [Experience in clinical training of nursing students]. PMID- 6921463 TI - [Pre- and postoperative nursing of patients with enterostomy]. PMID- 6921464 TI - [Planning of nursing care of a patient with enterostomy. A case study]. PMID- 6921465 TI - [Assistance in social rehabilitation of a schizophrenic patient]. PMID- 6921466 TI - [In search of new nursing philosophy. XXI. A relationship hindering a new goal in life]. PMID- 6921467 TI - [Infantile autism and description by Kanner]. PMID- 6921468 TI - Rationalization mark II--report to date. PMID- 6921470 TI - Suggested curriculum outline for psychiatric nurses. PMID- 6921469 TI - Statement issued from the office of the Minister for Health, Laurie Brereton, MP. PMID- 6921471 TI - Orientation programme for third year medical students. PMID- 6921472 TI - Community awareness. Assessment of levels of community awareness of the facilities available at community health centres in the lower Hunter Region during 1980. PMID- 6921473 TI - Characteristics of employed nurses in West Michigan health service area. PMID- 6921474 TI - Comparable worth study shows state classification system discriminates. PMID- 6921475 TI - Due process in termination. PMID- 6921476 TI - The grievance procedure. PMID- 6921477 TI - Expression of breast milk. PMID- 6921478 TI - Home birth--running the gauntlet. PMID- 6921479 TI - Alternative positions in childbirth. PMID- 6921480 TI - Low-level lead exposure and its effects on human beings. PMID- 6921481 TI - Male widwives. PMID- 6921483 TI - "The practising midwife". PMID- 6921482 TI - The prevention of perinatal morbidity and mortality. PMID- 6921484 TI - Wanted: encouragement. PMID- 6921485 TI - Postscript patience--a critique of current third stage practice. PMID- 6921486 TI - Depression--a new aspect? PMID- 6921487 TI - The nurse practitioner role. PMID- 6921489 TI - Reorganisation of the NHS. PMID- 6921488 TI - Cathepsin G from human polymorphonuclear leukocytes cleaves human IgM. AB - Cathepsin G, the chymotrypsin-like enzyme from human polymorphonuclear leukocytes, cleaves human IgM and produces two major fragments that closely resemble those released by leukocyte elastase digestion of IgM. An F(ab)2 mu-like fragment, mol. wt 140,000, retains some reactivity with an anti-Fc mu antiserum and is antigenically deficient with respect to the IgM subunit. The other fragment is an Fab mu-like product with a mol. wt of 54,000. Both cathepsin G fragments are indistinguishable from the elastase counterparts by immunochemical analysis. An Fc mu fragment could not be recovered. The kinetic course of the cleavage shows that cathepsin G produces Fab mu fragments at a higher rate than F(ab)2 mu, whereas the contrary is valid for elastase. Beside the two major fragments and low mol. wt peptides, cathepsin G releases also a product with the same mol. wt and immunological reactivity as the IgM subunit. The biological significance of the interaction between IgM and leukocyte proteinases is discussed. PMID- 6921490 TI - Flight of fancy. PMID- 6921491 TI - Computers in theatres: friend or foe? PMID- 6921493 TI - The role of the theatre nurse with the surgical team. PMID- 6921492 TI - Communications: the school nurse; the theatre nurse. PMID- 6921494 TI - Planning operating departments No. 3. The planning of operating theatre suites. PMID- 6921495 TI - Nursing is like a fat person. PMID- 6921496 TI - Just different: not better. PMID- 6921497 TI - A comparison between hemodialysis treatment and locus of control. PMID- 6921498 TI - Direct blood pressure recording during acute hemodialysis: a simplified method. PMID- 6921499 TI - Strong investment programs save taxes, bolster income. PMID- 6921500 TI - Consider yourself for a change: the phenomenon of burn-out. PMID- 6921501 TI - Chronic renal failure and the common denominator theory: a practical application. PMID- 6921502 TI - Accent on people. PMID- 6921504 TI - The right to health care: reflections and implications for nursing administrators. PMID- 6921503 TI - The geriatric ESRD patient...a unique problem in patient care. PMID- 6921505 TI - On the scene: University of California Irvine Medical Center. Self-influence as a means for professional influence within a health care system. PMID- 6921506 TI - Developing a peer review process to facilitate skill acquisition for clinical performance and advancement. PMID- 6921507 TI - On the scene: University of California Irvine. Influencing change agents. PMID- 6921508 TI - On the scene: University of California Irvine. Up the ladder: development of a clinical series job description. PMID- 6921510 TI - Clinical nurse instructor: impact on a nursing unit. PMID- 6921509 TI - Clinical evaluation of patient outcome: an influence for change. PMID- 6921511 TI - On the scene: University of California Irvine. Peer group support: a means to self-care. PMID- 6921513 TI - Implementing conceptual job descriptions: a retrospective view. PMID- 6921514 TI - Nursing action research: using clinical nurse instructors. PMID- 6921516 TI - Influence and action. PMID- 6921512 TI - Recruitment and retention: a staff self-promotional model. PMID- 6921515 TI - The emperor's new clothes. PMID- 6921517 TI - The nursing service administrator: a democratic authority figure. PMID- 6921519 TI - Nurse power for the 1980s. PMID- 6921518 TI - The role of the nursing administrator in practice. PMID- 6921521 TI - Patients' rights and the preservation of human dignity. PMID- 6921520 TI - The process of influencing decisions. PMID- 6921523 TI - Simulated cardiopulmonary arrests in a hospital setting. PMID- 6921522 TI - The socialization process: a student's viewpoint. PMID- 6921525 TI - MIC: a self-directed learning method for nursing staff. PMID- 6921524 TI - A clinical performance evaluation tool for a process-oriented nursing curriculum. PMID- 6921526 TI - The socialization of nurse-faculty. PMID- 6921527 TI - Test your knowledge of contemporary nursing part 3. PMID- 6921528 TI - The Prescott principle. PMID- 6921529 TI - Respiratory arrest: are you prepared? PMID- 6921532 TI - Taming the cardiac monitor. Earn CEUs. PMID- 6921531 TI - The operation's over, but the danger's not. PMID- 6921535 TI - Should you crush that tablet? PMID- 6921534 TI - Emergency! First aid for burns. PMID- 6921533 TI - Abruptio placentas. PMID- 6921530 TI - Deciphering diagnostic studies: carcinoembryonic antigen. PMID- 6921536 TI - Recognizing fluid and electrolyte imbalance. PMID- 6921537 TI - [Teaching patient with chronic bronchopulmonary diseases]. PMID- 6921538 TI - [Hypothesis of the conceptual framework in nursing]. PMID- 6921540 TI - [A society more alive than ever]. PMID- 6921539 TI - [Nurses' responsibility for the needs of ostomates]. PMID- 6921541 TI - [The P.R.N. system: advantages and limitations]. PMID- 6921542 TI - [Breast self-examination by familiarization of the body]. PMID- 6921543 TI - [Inspection... again an inspection?]. PMID- 6921544 TI - [Nurses and the fight against respiratory diseases]. PMID- 6921545 TI - [A look back at professional inspection visits]. PMID- 6921546 TI - [Psychosomatic medicine in Quebec: current perspectives]. PMID- 6921547 TI - [Rights and liberties of the dying]. PMID- 6921549 TI - [A nurse at James Bay]. PMID- 6921550 TI - [Hyperbaric oxygenation]. PMID- 6921552 TI - [Nurse's responsibility concerning legal aspects in psychiatry]. PMID- 6921553 TI - An analysis of the attributes and relationships within an HMO. PMID- 6921551 TI - [Community psychiatric nurse: a challenge for the 80s]. PMID- 6921554 TI - Toward autonomy of the nursing profession. PMID- 6921548 TI - [Splendors and miseries of nursing education]. PMID- 6921555 TI - Relationship between self-actualization scores of staff nurses and burnout syndrome symptoms. PMID- 6921556 TI - Are baccalaureate students prepared to assume first-level management position? PMID- 6921557 TI - The issue of licensure--institutional vs. individual. PMID- 6921558 TI - Nurse educators in role transition: establishing an independent practice. PMID- 6921559 TI - The pay struggle - nurse managers' role. PMID- 6921560 TI - Legal notes: dismissal for dishonest conduct. PMID- 6921563 TI - Diabetes - Newcastle's programme of action. PMID- 6921561 TI - Tomorrow's elderly: who will care? PMID- 6921562 TI - Enhancing old age: the role of nursing. PMID- 6921565 TI - Strike action - what then? PMID- 6921564 TI - The management of clinical specialties - r. The nurse's role in the management of a haemophilia centre. PMID- 6921566 TI - The American alternative for directors of nursing. PMID- 6921567 TI - The school nurse. PMID- 6921568 TI - Occupational health service. The management of clinical specialties. 6. PMID- 6921569 TI - Managing employee performance. PMID- 6921570 TI - Motivation & dissatisfaction. PMID- 6921572 TI - Nursing: patient care & computers. How they work together. PMID- 6921571 TI - Yes--with reservations. PMID- 6921573 TI - Selecting the right computer system. PMID- 6921574 TI - Computers. PMID- 6921575 TI - A computerized patient information system. PMID- 6921576 TI - Designing and developing a computerized hospital information system. PMID- 6921577 TI - The computer as a clinical tool. PMID- 6921578 TI - Computerization of nursing. PMID- 6921579 TI - Art and science of management: up the ladder. PMID- 6921580 TI - Law for the nurse manager: when physician violates hospital policies. PMID- 6921581 TI - Nursing: heads or tails? PMID- 6921583 TI - The nurse practitioner: an extended role in nursing. PMID- 6921582 TI - The brouhaha over supplemental nursing services. PMID- 6921584 TI - Financial nurse: tax saving strategies. PMID- 6921585 TI - Study tours: one option for CE. PMID- 6921587 TI - The supplemental nursing service: can't live with it, can't live without it. PMID- 6921588 TI - Primary nursing: another match patient-nurse interaction. PMID- 6921586 TI - The nursing shortage - 50 years old? PMID- 6921590 TI - American Nurses' Association: a force through history. PMID- 6921589 TI - AMI: the International Health Care Services Company. PMID- 6921591 TI - When nurses compete: nurse midwives denied hospital privileges. PMID- 6921592 TI - Air ions and office health. PMID- 6921593 TI - Helping employees to stop smoking. A report on the use of a self help manual with group support. PMID- 6921594 TI - Safety training: not more, but better. PMID- 6921595 TI - Research in OH nursing. PMID- 6921597 TI - Health screening: 1. PMID- 6921596 TI - Safety: the social implications of shift work. PMID- 6921598 TI - Setting up a counselling service in the workplace. PMID- 6921599 TI - Evaluation of cancer screening and education program 1982. PMID- 6921600 TI - Nurse health assessment: the new "physical" in American industry. PMID- 6921602 TI - Drugs and dosages: streptase. PMID- 6921601 TI - Doctor warns against overreaction to genital herpes. PMID- 6921603 TI - The effects of a master's degree in occupational health on the delivery of services to workers. PMID- 6921604 TI - Careers. Adult behavioural psychotherapy. PMID- 6921605 TI - [The need of the older person for care]. PMID- 6921608 TI - The Nestle boycott: background and issues. PMID- 6921606 TI - [Intermediate WHO program: nursing process model in Austria]. PMID- 6921609 TI - Ever think about developing your own CE offering? Here's what it takes! PMID- 6921607 TI - [Employee occupational safety in hospitals]. PMID- 6921611 TI - The gifted preschool child. PMID- 6921610 TI - A nonsmoking generation is not a pipe dream. PMID- 6921612 TI - Group well-child care: an option for today's children. PMID- 6921613 TI - Parents' perceptions of parenting support systems. PMID- 6921614 TI - Food for thought: impact of a supplemental nutritional program on low-income preschool children. PMID- 6921615 TI - A questionnaire for assessment of parents' needs in a child health clinic. PMID- 6921616 TI - Childhood obesity: a treatment approach for private practices. PMID- 6921618 TI - A self-instructional approach to oral cavity screening. PMID- 6921617 TI - The learning-disabled child: recognition, evaluation, and management. NAPNAP continuing education series. PMID- 6921619 TI - Pediatric management problems: tension headaches. PMID- 6921620 TI - Point: "bring those 'outside' observers in". AB - A teaching hospital is frequently overwhelmed by the number of people who want to observe a working therapeutic group; therefore the need to provide and enhance this experience for group members and leaders led us to try a new approach. After some initial experimentation, the technique of an observer participating through feedback sessions within the group made a major impact on members, leaders, and observers. Observers were held accountable for the privilege of joining the group experience, and the passiveness, which usually accompanies non-participation, decreased notably. And last, but certainly not least in our experience, patients felt less exploited when the unseen people shared their observations with them. Bringing these outside observers in helped the group's potential to develop more fully. PMID- 6921621 TI - Counterpoint: "don't bring those 'outside' observers in". PMID- 6921622 TI - A volunteer support system for the chronically mentally ill. PMID- 6921624 TI - Learned helplessness: from concept to comprehension. PMID- 6921623 TI - Certification as a credential: what are the issues? PMID- 6921625 TI - Helping patients control their own money: money management training. PMID- 6921626 TI - Community mental health nursing: its unique role in the delivery of services to ethnic minorities. PMID- 6921628 TI - A guide for time studies. PMID- 6921630 TI - The nurse listening to the adolescent. Contraception problems in adolescents. PMID- 6921631 TI - Adolescence. PMID- 6921627 TI - Simulation games as a teaching technique in psychiatric nursing. PMID- 6921632 TI - Meeting of adolescents. PMID- 6921633 TI - Nursing care practice and the application of the holistic care concept to the hospitalized adolescent. PMID- 6921629 TI - The nucleotide sequence of a glutamine tRNA from rat liver. AB - A glutamate tRNA from rat liver was purified. By means of post-labeling techniques, its nucleotide sequence was shown to be: pU-C-C-C-A-C-A-U-m1G-G-U-C psi-A-G-C- G-G-D-D-A-G-G-A-U-U-C-C-U-G-G-psi-U-mcm5S2U-U-C-A-C-C-C-A-G-G-C-G- G-C m5C-m5C-G-G-G-Tm-psi-C-G-A-C-U-C-C-C-G-G-U-G-U-G-G-G-A-A-C-C-AOH. The sequence is remarkably similar to that of tRNAGlu from Drosophila melanogaster. Only 10 out of 75 nucleotides in the two tRNAs are different. PMID- 6921634 TI - Return to school... nurse in school. PMID- 6921636 TI - Synthesis of public health science and nursing science. PMID- 6921635 TI - Sex conference - planning - sexually transmitted diseases. PMID- 6921637 TI - Conflict resolution. PMID- 6921638 TI - Discovering resources for continuing education. PMID- 6921639 TI - Nursing reclaims its role. PMID- 6921642 TI - Network: getting into print. PMID- 6921640 TI - Community health is community competence. PMID- 6921641 TI - When a women heads the household. PMID- 6921643 TI - Let's get down to work. Interview by Alison Dunn. PMID- 6921645 TI - The new MH bill: what it means for nurses. PMID- 6921644 TI - The new MH bill: what it means for nurses. PMID- 6921646 TI - A handicap? PMID- 6921647 TI - Renal replacement therapy. 12. Some treatments associated with dialysis. PMID- 6921648 TI - Failure or success? PMID- 6921649 TI - Counselling in psychiatric nursing--2. PMID- 6921650 TI - McKnight Unit--a progressive approach to rehabilitation? PMID- 6921651 TI - Feelings. Changing what we are. PMID- 6921652 TI - Feelings. 1. Learning from practical experience. PMID- 6921653 TI - Feelings. 2. 'Just imagine.'. PMID- 6921654 TI - Wound care. No. 11. Which dressing and why - 1. PMID- 6921655 TI - Sex and the singular nurse. PMID- 6921656 TI - The shape of things to come. PMID- 6921657 TI - What's in store? Nursing input to the supplies service. PMID- 6921658 TI - What's in store? 1. The other Salmon report - implications for the nursing service of the Supply Council. PMID- 6921659 TI - What's in store? 1. A 'nurse for equipment. PMID- 6921660 TI - Nursing management of the leg ulcer in the community. PMID- 6921661 TI - Karaya gel in the treatment of leg ulcers. PMID- 6921662 TI - Care studies in a hospice. PMID- 6921663 TI - The first low energy hospital. PMID- 6921664 TI - Day in the life of a picket. PMID- 6921665 TI - How I see the future of the NHS. PMID- 6921666 TI - Day for night: circadian rhythms in the elderly. PMID- 6921667 TI - Nursing care study: a behavioural programme for Billy. PMID- 6921668 TI - What's in store? 2. Good housekeeping at Wythenshawe. PMID- 6921669 TI - Manpower information, payroll and occupation codes. PMID- 6921670 TI - 'Lies, damned lies and statistics'. PMID- 6921671 TI - The nurse and bedside blood tests. PMID- 6921672 TI - The education of children in hospital. PMID- 6921673 TI - Dedicated followers of fashion? PMID- 6921674 TI - Systems of life No 92. Systems and signs: nervous system. Testing reflexes. PMID- 6921675 TI - Seven ages of disability: the sixth age. PMID- 6921676 TI - Evaluation of a regional library service for nurses and paramedical groups in the Northern Region. PMID- 6921677 TI - It's make your mind up time! PMID- 6921678 TI - Sheila Quinn: climaxing a career with the Rcn presidency. Interview by Laurence Dopson. PMID- 6921679 TI - Psychological treatments of chronic pain. PMID- 6921680 TI - The Mecabed. PMID- 6921681 TI - Balancing the books. 1. Budget processes and budgeting in the new authorities. PMID- 6921682 TI - Hospital admission through the parents' eyes. PMID- 6921683 TI - Ethical considerations in nursing. PMID- 6921684 TI - How to cope with professional challenges. PMID- 6921685 TI - Challenge in administration. PMID- 6921686 TI - Psychiatry/mental handicap forum 7: Cornelia de Lange syndrome: my giggling little man. PMID- 6921687 TI - Psychiatry/mental handicap forum 7: family interaction: talking back to happiness. PMID- 6921688 TI - A minister's marketing of Megaw. PMID- 6921689 TI - Education: strangers in the ward. PMID- 6921690 TI - Matty was there: relationship of a couple during the last few months of the wife's terminal illness. PMID- 6921692 TI - Clinical comment: schizophrenia. PMID- 6921691 TI - Nursing care study. How many tablets should I take to kill myself? PMID- 6921693 TI - Praying for cooperation. PMID- 6921694 TI - Depression. PMID- 6921695 TI - Nursing care study. Strained relations: dementia. PMID- 6921696 TI - Group dynamics 2: under the influence. PMID- 6921697 TI - Retirement: freedom of choice. PMID- 6921700 TI - Community nursing services: goodbye Uncle Tom Cobley--and all. PMID- 6921699 TI - Developments in nursing 1. Shaping the profession's future. PMID- 6921701 TI - My personal water torture. PMID- 6921702 TI - Careers: drug dependency nursing: one hundred lives in the balance. PMID- 6921703 TI - Theory and practice. Sharing good ideas. PMID- 6921704 TI - Theory and practice. Caught in no-man's land. PMID- 6921698 TI - Cytology 2: a routine sample. PMID- 6921705 TI - Theory and practice. The future of assessment. PMID- 6921706 TI - Care of the elderly: growing old in Europe. PMID- 6921707 TI - Pressure sores: a system of prevention. PMID- 6921708 TI - Anytown anecdotes: the Willow pattern. PMID- 6921709 TI - Nursing care study: a testing time. PMID- 6921710 TI - Clinical comment. Virus infections. PMID- 6921711 TI - Star patient. PMID- 6921715 TI - Models in health care: a double-edged weapon. PMID- 6921712 TI - Antenatal health education: a shared experience. PMID- 6921714 TI - A fair say in the future. PMID- 6921713 TI - Issues in nursing 8: Look back in anger. PMID- 6921716 TI - Nursing care study: best at bathtime. PMID- 6921717 TI - Reorganisation: bridging the great divide. PMID- 6921718 TI - Education. Living in the real world. PMID- 6921719 TI - Pharmacology: Prostin VR. PMID- 6921721 TI - Careers: combined RMN and BSc course. Learning by degree. PMID- 6921720 TI - Representation: advice for the advisers. PMID- 6921722 TI - The occupational health nurse. Room for improvement. PMID- 6921723 TI - The occupational health nurse. A change of venue. PMID- 6921724 TI - The occupational health nurse. Towards a golden year. PMID- 6921727 TI - Nurse practitioners: starting from scratch. PMID- 6921726 TI - NHS awaits efficiency blitz. PMID- 6921725 TI - The occupational health nurse. A healthy future. PMID- 6921728 TI - Issue in legislation: statute for a better service. PMID- 6921729 TI - Nursing care study: more growing pains than usual. PMID- 6921730 TI - Wanted: a new car deal. PMID- 6921733 TI - A case for the birthing chair. PMID- 6921732 TI - Natural childbirth: focus on the family. PMID- 6921731 TI - Management. 1. Find a quiet room and think about nursing. PMID- 6921734 TI - Ward design: central to care. PMID- 6921735 TI - After the hysterectomy. PMID- 6921736 TI - After the hysterectomy. A London hospital's approach. PMID- 6921737 TI - Volunteers: willing hands. PMID- 6921738 TI - Nursing care study: commuter care. PMID- 6921739 TI - Drug abuse: A refuge in times of crisis. PMID- 6921740 TI - Drug abuse. Barbiturates: a history of abuse. PMID- 6921741 TI - Whose pregnancy is it anyway?. Interview by Mike McCormack. PMID- 6921742 TI - Nursing care study: in a world of her own. PMID- 6921744 TI - Management 2: You scratch my job and I'll scratch yours. PMID- 6921743 TI - Trans-sexual surgery: a woman in the making. PMID- 6921745 TI - Nursing care study: looking for a long-term solution. PMID- 6921746 TI - Looking for a long-term solution: clinical comment. PMID- 6921747 TI - Psychiatry in general nursing: a case study of me, by me. PMID- 6921748 TI - Open heart surgery: a day out in the theatre. PMID- 6921749 TI - Ordeal by harassment. PMID- 6921750 TI - Nurses' pay: what the public think. PMID- 6921751 TI - Anytown anecdotes: a quiet old lady. PMID- 6921752 TI - Midwifery in America: outlaws in the west. PMID- 6921753 TI - Environments 1: Scenes of improvement. PMID- 6921755 TI - Careers: theatre nursing. Operational skills. PMID- 6921754 TI - A taste of my own medicine. PMID- 6921756 TI - The art of observation. 1. Aspects of grief. PMID- 6921757 TI - Cardiopulmonary resuscitation: a change of rhythm. PMID- 6921758 TI - Yaws. PMID- 6921760 TI - Clinical forum 8: Intensive care. The nurses' critical role. PMID- 6921759 TI - Unshelving a problem. PMID- 6921761 TI - Clinical forum 8. Intensive care. Chest injuries. I. Initial treatment. PMID- 6921762 TI - Clinical forum 8. Intensive care. Chest injuries. II. Clinical management. PMID- 6921763 TI - Clinical forum 8. Intensive care. Chest injuries. III. Complications. PMID- 6921764 TI - Clinical forum 8: Intensive care. Relatively speaking. PMID- 6921765 TI - Nursing care study: fighting phobias with drugs. PMID- 6921766 TI - Education improves expectations. PMID- 6921767 TI - Management. 3. May the force be with you. PMID- 6921768 TI - Community nursing: a gradual return. PMID- 6921769 TI - Geriatrics: organisers needed. PMID- 6921770 TI - The anatomy of the brain. PMID- 6921774 TI - Health care in Israel: covered by insurance. PMID- 6921772 TI - Deep vein thrombosis: an unexpected killer. PMID- 6921771 TI - Nursing care study: fetoscopy and intrauterine death. PMID- 6921775 TI - Careers. Community midwifery: a personal approach. PMID- 6921776 TI - Radiation therapy as primary treatment for breast cancer. PMID- 6921777 TI - Hazards of working with cytotoxic agents--a response. PMID- 6921778 TI - Philosophy statement shared. PMID- 6921773 TI - Tiaprofenic acid. PMID- 6921779 TI - Radical vulvectomy: physical, psychological, social and sexual implications. PMID- 6921780 TI - Patient care evaluation: a comparison of current practice and nursing literature for oral care of persons receiving chemotherapy. PMID- 6921781 TI - Intravenous therapy guidelines for oncology practice. PMID- 6921782 TI - Patient participation in monitoring myelosuppression from chemotherapy. PMID- 6921783 TI - Theories and intervention of nutritional deficit in neoplastic disease. PMID- 6921784 TI - Elimination. Practice corner. PMID- 6921786 TI - Research questions and answers. Health locus of control. PMID- 6921785 TI - Research questions and answers. Patient access in research. PMID- 6921787 TI - The use of dexamethasone (Hexadrol) as an antiemetic in association with chemotherapy for neoplastic disease. PMID- 6921788 TI - High dose metoclopramide as an antiemetic for patients receiving chemotherapy with cis-platinum. PMID- 6921789 TI - Clinical use of droperidol (Inapsine) in patients with chemotherapy induced nausea and vomiting. PMID- 6921790 TI - The influence of the time of administration on cis-platinum induced nausea and vomiting. PMID- 6921793 TI - Recreation therapy: a humanistic adjunct to oncology treatment. PMID- 6921791 TI - Critical problems facing young adults with cancer. PMID- 6921794 TI - Protective isolation. PMID- 6921792 TI - Cancer patients' knowledge of chemotherapy: assessment and informational interventions. PMID- 6921796 TI - Ventilation. Practice corner. PMID- 6921795 TI - Development of two booklets for cancer patients. PMID- 6921797 TI - Today's nuclear threat. Keynote address. PMID- 6921798 TI - Call me healthy. The Mara Mogensen Flaherty memorial lecture. PMID- 6921799 TI - Health beliefs and their influence on breast self-examination practices in women with breast cancer. PMID- 6921800 TI - Vesicant first. PMID- 6921801 TI - Musculoskeletal assessment: cranial nerve assessment with halo traction. PMID- 6921803 TI - Drug bulletin: zomepirac sodium (Zomax). PMID- 6921802 TI - Jehovah's Witnesses and the problem with blood. PMID- 6921804 TI - The limping child. PMID- 6921805 TI - Pathophysiology of the diabetic foot: implications for the orthopedic nurse. PMID- 6921806 TI - [Plasma kininogen and prekallikrein activity in hypertensive patients depending on the type and stage of hypertension]. PMID- 6921808 TI - The measurement of pain. PMID- 6921807 TI - [Serum immunoglobulins, C3 and C4 complement components and C3 activator in children with joint-affecting diseases]. PMID- 6921810 TI - Why servo-analgesia? PMID- 6921809 TI - A nursing pain society? PMID- 6921812 TI - Nurses complaints about doctors: legal aspects. PMID- 6921811 TI - The renal kallikrein-kinin system and sodium excretion. PMID- 6921813 TI - Restraining patients in psychiatric units: legalities. Case in point: people v. Futterman (449 N.Y.S. 2d 108 - NY). PMID- 6921814 TI - Legal case briefs for nurses. KS: nurses, doctors in OBS negligence. GA: emergency unit M.D./RN care: OBS. PMID- 6921815 TI - Doctors, nurses and consent forms: misunderstandings. Case in point: Okehi V. St. Paul (289 S.E. 2d 810 - GA). PMID- 6921816 TI - Sex discrimination charges: male nurses. Case in point: Backus v. Baptist Medical Center (671 F. 2d 1100 - ARK.). PMID- 6921818 TI - "Restrain as needed": nursing judgment required. Case in point: Sexton v. St. Paul (631 S.W. 3d 270 ARK.). PMID- 6921817 TI - Legal case briefs for nurses. IN: Pediatrics: pre-discharge injury; ME: Surgery: sponge count error. PMID- 6921819 TI - Sudden infant death syndrome: parents' perceptions and responses to the loss of their infant. AB - Sudden Infant Death Syndrome (SIDS) is the number one killer of infants under one year of age. Families are left in a state of crisis after a baby dies of SIDS. Thus, crisis counseling has been offered routinely to SIDS parents in King County, Washington. The purpose of this retrospective study was to assess whether mothers differed significantly from fathers in their perception of the situation, their feelings experienced and expressed, their approaches to problem solving, and the support they received. Differences in reactions between single and married parents were also studied. The 48% return rate produced a sample of 54 parents, 37 mothers and 17 fathers, who had lost their infant to SIDS. Statistically significant differences were found between mothers and fathers, as well as between single and married parents, in their view of the SIDS event, their problem solving approaches, and support systems. The results provide useful information for nurses in counseling SIDS parents and in working with families during and after subsequent pregnancies. PMID- 6921820 TI - The relationship between life change events, social supports, and dysmenorrhea. AB - A survey of 156 female undergraduate nursing students was conducted to determine the relationship between life change events and dysmenorrhea and the mediating effect of social supports on this relationship. Data were collected using the Anderson College Schedule of Recent Experience (subjects estimated personal readjustment to life changes), the Moos Menstrual Distress Questionnaire, and a social support index constructed by the authors. Correlations were obtained separately for high and low social support groups; these ranged from .19 to .62 and were significant (p less than .05) for both groups. Presence or absence of a confidant was the most discriminating social support dimension (r = .32 for those with a confidant and .62 for those without). For subjects using oral contraceptives there was no relationship between life change and dysmenorrhea, while users of other contraceptives showed a significant positive relationship (p less than .05). Life change and social supports together accounted for only 16% of the variance in menstrual distress scores. Methodological difficulties in using the life change and social support tools were identified. PMID- 6921822 TI - A model for assessing potential adaptation to stress. AB - The purposes of this study were to determine if hospitalized medical-surgical patients could be classified reliably according to their potential to adapt to stress; and to explore the relationship between their adaptive potential and length of hospital stay. Forty-six patients were selected for participation by use of a table of random numbers. Three classes of significantly different adaptive potential were identified: the Alarm and Impoverished states were considered as stress states, while the state of Equilibrium was considered a nonstress state. Although it was possible to distinguish stress from nonstress states, using only physiological parameters, psychological parameters were required to distinguish between the two stress states. The differentiation among the three coping states was used to predict subjects' potential for mobilizing adaptive resources. Length of hospitalization was then related to classification of adaptive potential. PMID- 6921821 TI - Estimating perimenstrual distress: a comparison of two methods. AB - The purpose of this study was to compare two methods of measuring menstrual distress. Seventy-three women, 18 to 35 years of age, selected from lower-middle to upper-middle income neighborhoods kept a daily diary for a two-month period. Following completion of the diary, the women responded to the Moos Menstrual Distress Questionnaire (MDQ) with reference to their last menstrual period. Estimates for all symptoms on the MDQ exceeded those in the diary. The greatest discrepancies between the two methods were found for water retention and negative affect symptoms. Concordance of perimenstrual symptom reporting across the two measures was statistically significant only for menstrual cramps, K = .248, p less than .021, and premenstrual backache, K = .203, p less than .036). Although these results suggest that estimates of dysmenorrhea symptoms are least affected by the data collection method, they are consistent with the hypothesized joint effects of menstrual stereotypes and recall bias on retrospective symptom reports; these sources of bias should be considered in future menstrual, distress research. PMID- 6921823 TI - Arthritis self-management: a patient education program. PMID- 6921824 TI - Rehabilitation nurse and patient predictions of service needs. PMID- 6921825 TI - Brain injury and family education needs. PMID- 6921826 TI - Spinal cord injured women's concerns: menstruation and pregnancy. PMID- 6921828 TI - Identifying social needs of patients with neuromuscular disorders. PMID- 6921827 TI - A record-keeping method for hospice-related volunteers. PMID- 6921829 TI - Code 99: a rehabilitation patient in arrest. PMID- 6921831 TI - [Nursing prisoners]. PMID- 6921830 TI - [Treatment of severe infections and septicemia caused by S. aureus (author's transl)]. PMID- 6921832 TI - [Nursing care of unconscious patients]. PMID- 6921833 TI - [Brucellosis]. PMID- 6921834 TI - [Acute appendicitis]. PMID- 6921835 TI - [Management of dentition disorders and changes in childrens' dentition]. PMID- 6921836 TI - [General health management in asthmatics]. PMID- 6921837 TI - [Technique: tracheostomy]. PMID- 6921838 TI - [Treatment of furunculosis]. PMID- 6921839 TI - [Health Charter]. PMID- 6921840 TI - 'How I made passing meds a full-time affair'. PMID- 6921841 TI - Diabetes today: a startling new body of knowledge. C.E. elective. PMID- 6921842 TI - It's not artificial blood--but can do the work of RBCs. PMID- 6921843 TI - Confessions: desperate measures. PMID- 6921845 TI - Surviving on-the-job conflict. PMID- 6921844 TI - Emergency burn care: those crucial first minutes. PMID- 6921846 TI - What to watch for with coumarin. PMID- 6921847 TI - For a really thorough abdominal exam.... PMID- 6921848 TI - Starting this month: "refreshers" on pulmonary studies. PMID- 6921849 TI - Opinion exchange: how much can you promise a patient? PMID- 6921850 TI - What to do if your supervisor orders a "cover-up". PMID- 6921851 TI - Sound off! Phase out nursing? We're asking for it. PMID- 6921852 TI - A male nurse is more than muscle! PMID- 6921853 TI - The career/parent dilemma. Nurse and mother--on the job. PMID- 6921854 TI - Topicals: a welter of options calls for refined application techniques. PMID- 6921855 TI - What computers can do for you...and what they're already doing for the lucky few. PMID- 6921856 TI - A sinfully easy way to interpret ABGs. PMID- 6921857 TI - Stanching nosebleeds: a complete guide. PMID- 6921859 TI - Panic in the delivery room. PMID- 6921858 TI - What to watch for with antacids. PMID- 6921860 TI - The fine art of giving a physical. Assessing the heart: what's normal and what's not. PMID- 6921861 TI - Preparing for two uncomfortable tests: gastric analysis and liver biopsy. PMID- 6921862 TI - KVOs: how fast is fast enough? PMID- 6921863 TI - On our own: the inspiring story of two nurses who challenged the system--and won. PMID- 6921864 TI - Legally speaking: caution: home visits can be hazardous to your license. PMID- 6921866 TI - Sound off! Contemporary myths: the TV hospital; the male nurse. PMID- 6921865 TI - Advice of counsel: RN's legal advisory service. PMID- 6921867 TI - Home care nursing: come along for a day. PMID- 6921868 TI - Association future rests with members: Presidential address. PMID- 6921870 TI - Rights duties obligations. PMID- 6921869 TI - Nursing assessment committees: how the professional clause and nursing committees function in overload situations. PMID- 6921871 TI - [Biological effects of radiation]. PMID- 6921872 TI - [Protection against radiation]. PMID- 6921873 TI - [Radiation in medicine. A field in perpetual development]. PMID- 6921874 TI - [Use of artificial radioelements in nuclear medicine]. PMID- 6921875 TI - [The detection of radiation]. PMID- 6921878 TI - [Diagnostic use of x rays]. PMID- 6921877 TI - [Role of the manipulator in radiotherapy]. PMID- 6921876 TI - [Nurse's role in radiotherapy]. PMID- 6921879 TI - [An example of radiotherapeutic treatment. Irradiation of cancer of the uterine cervix]. PMID- 6921880 TI - [The health chart]. PMID- 6921881 TI - [Women and the social rights]. PMID- 6921882 TI - [Disclosing the diagnosis, pre-operative tests]. PMID- 6921883 TI - [Coronary arteries: anatomy, physiology, anatomopathology, physiopathology]. PMID- 6921884 TI - [Infection in osteo-articular pathology]. PMID- 6921885 TI - [Indications for coronography: surgical indications]. PMID- 6921887 TI - [Development of research in the nursing profession]. PMID- 6921886 TI - [Nursing research in nursing care: scientific basis of practice]. PMID- 6921888 TI - [Education of patients using anti-coagulants: utopia or reality?]. PMID- 6921889 TI - [Living with an artificial valvular prosthesis]. PMID- 6921890 TI - [Nursing care and research]. PMID- 6921891 TI - [Nursing research and nursing education]. PMID- 6921892 TI - [Nursing care and human sciences]. PMID- 6921893 TI - [Place of the mother in the nursing care of her hospitalized child]. PMID- 6921895 TI - [Nursing care and human sciences]. PMID- 6921894 TI - [Care in psychiatry is before everything else communication]. PMID- 6921896 TI - [Death and we...]. PMID- 6921897 TI - [Ethnology and nursing care]. PMID- 6921898 TI - [Study on nursing care and nursing services: night nursing]. PMID- 6921902 TI - Determination of factor XII in plasma using the kallikrein substrate chromozym PK. PMID- 6921899 TI - [Night nursing]. PMID- 6921900 TI - [Proposal for the management and reevaluation of night work]. PMID- 6921901 TI - Credentials at risk. PMID- 6921903 TI - [Health care and capitalism]. PMID- 6921905 TI - [Nursing legislation: a rapidly unraveling emergency dressing]. PMID- 6921906 TI - [Patient's ombudswoman in the hospital]. PMID- 6921904 TI - [Support of self-care - the essence of nursing. II. A critical analysis of J. van den Brink-Tjebbes' nursing theory]. PMID- 6921907 TI - [Vitamins. II. Water-soluble vitamins]. PMID- 6921908 TI - A method for determination of human urinary inactive kallikrein (prekallikrein). AB - Inactive kallikrein (prekallikrein) in human urine was discovered recently. A more accurate method to measure this zymogen and total kallikrein is described. With trypsin pretreatment, it was found that 35.3 +/- 2.7% of total urinary kallikrein activity was prekallikrein. The results are supported by a new direct radioimmunoassay which measures predominantly active kallikrein. PMID- 6921909 TI - The Commission on Graduates of Foreign Nursing Schools: a special report. PMID- 6921910 TI - Interview: Febes Kavanagh. PMID- 6921911 TI - How to improve your patient education. PMID- 6921912 TI - How to improve your blood pressure measurement technique. PMID- 6921913 TI - Interview: Susan Hurst, Frank Barse, Linda McCoy. PMID- 6921914 TI - Robotics and health: the therapeutic story behind the congress robot. PMID- 6921916 TI - Interview: Ellen Murphy. PMID- 6921915 TI - The perioperative role: new avenue for risk management. PMID- 6921917 TI - Let staff solve problems: develop a quality circle. PMID- 6921918 TI - Stress and the OR: make it work for you. PMID- 6921919 TI - OR management and the nursing student. PMID- 6921921 TI - How is nursing education faring in the 1980's? PMID- 6921922 TI - West Virginia's college bound nurses. PMID- 6921920 TI - Interview: Loretta Swit. PMID- 6921923 TI - Employment standards. PMID- 6921924 TI - [The kallikrein-kinin system and shock]. PMID- 6921925 TI - We think--therefore we are. Keynote address--A.A.R.N. Convention, April 19--23, 1982. PMID- 6921926 TI - Renal stones and urinary pH. PMID- 6921927 TI - Overcoming the language barrier: problems and solutions. PMID- 6921929 TI - Laser treatment of cervical neoplasia. PMID- 6921928 TI - Overcoming the language barrier: advice from an interpreter. PMID- 6921930 TI - Vascular access grafts in cancer chemotherapy. PMID- 6921931 TI - A case of acute fulminating meningococcemia. PMID- 6921933 TI - Nursing care of patients in shock part 2: fluids, oxygen, and the intra-aortic balloon pump. PMID- 6921934 TI - Seizures: a frequent side effect of ludiomil. PMID- 6921935 TI - Special report: drugs for two in lactation. PMID- 6921932 TI - Therapeutic relationship: a brief encounter. PMID- 6921936 TI - Ejaculatory disturbances with amoxapine. PMID- 6921937 TI - Time off: bafflegab. PMID- 6921939 TI - Revision of bylaws aims to make ANA more representative. PMID- 6921940 TI - Nursing schools face cuts, closings. PMID- 6921938 TI - Serum complement activity in pre-term pregnancies: relationship to duration of ruptured membranes and clinical infection. AB - Physiologic changes occurring during the latent period of prematurely ruptured membranes (PRM) are poorly understood. Indicators predicting maternal and neonatal infectious morbidity do not correlate well with clinical outcomes. A previous report suggested that in vivo complement consumption occurred in response to the event of membrane rupture. In this prospective study, complement activity was measured serially throughout the latent period in cases of preterm PRM. In addition to total hemolytic complement activity (CH50), C4-pro-activator (C3PA), a primary component of the alternate complement pathway, was measured in maternal and cord sera. As with CH50, cord serum C3PA levels are significantly less than those in matched maternal samples. Neither maternal nor cord serum complement activity correlated with either the duration of the latent period or maternal-neonatal infection. PMID- 6921941 TI - As I see it ... what can you do when cuts threaten your school? PMID- 6921942 TI - NLN endorses baccalaureate for entry. PMID- 6921943 TI - Nurses have much to gain from ERA ratification. PMID- 6921944 TI - As I see it ... contracts assure professional advances for nurses. PMID- 6921945 TI - Eunice Cole ready to lead ANA through transition period. PMID- 6921946 TI - ANA House adopts federation model. PMID- 6921948 TI - Britain's RCN is strong union with no-strike policy. Interview by Patricia McCarty. PMID- 6921947 TI - Nurse educators charge sex inequities at universities. PMID- 6921949 TI - Lean times mark 10th year for Indian nurse group. PMID- 6921950 TI - Connie Curran shares health tips on daily TV show in Milwaukee. PMID- 6921951 TI - Nurse credits contract as way to improve care. PMID- 6921955 TI - Business is remedy for some nurses. PMID- 6921953 TI - Work hazards, economic value of care discussed at Convention. PMID- 6921952 TI - As I see it: bylaws change, elections worry minority nurses. PMID- 6921954 TI - Advocates predict structure change will revitalize ANA. PMID- 6921956 TI - Here's help for the ethical dilemmas nurses face. PMID- 6921957 TI - New ANA President, executive learn media ins, outs. PMID- 6921958 TI - [Complement, a system of recognition of activation and amplification]. PMID- 6921960 TI - Approval process aids in planning effective education offerings. PMID- 6921959 TI - Antagonism of carbenicillin and cefamandole by cefoxitin in treatment of experimental infections in mice. AB - The ability of cefoxitin to antagonize the in vivo efficacy of cefamandole and carbenicillin as predicted by in vitro assays was analyzed in experimental infections in mice. Cefoxitin was administered in a nonprotective dose either at the time of challenge or simultaneously with the protective drug, 1 and 3.5 h postchallenge. In mice infected with Enterobacter cloacae, median 50% protective doses of cefamandole and carbenicillin were markedly increased by cefoxitin, especially when the latter was given at the time of challenge. The antagonistic effect was also associated with increased numbers of challenge bacteria present in animal heart blood within a 6.5-h period after infection. In infections with Pseudomonas aeruginosa, cefoxitin antagonized carbenicillin; however, the effect was less dramatic than that seen with E. cloacae. Antagonism in this model was pronounced with simultaneous administration of antagonizing and protective drugs. The antagonistic effects observed in all in vivo tests were not due to the selection of stable resistance to the protective drugs, but appeared to be due to a reversible induction of beta-lactamases by cefoxitin. PMID- 6921961 TI - A voice button for laryngectomees. PMID- 6921962 TI - OR team changes life for Hondurans. PMID- 6921963 TI - OR nurse's guide to preventing pressure sores. PMID- 6921964 TI - An externship in OR nursing. PMID- 6921965 TI - OR sanitation. Local survey shows degree of compliance with standards. PMID- 6921966 TI - A standard care plan for the operating room. PMID- 6921967 TI - OR design shows nurses' touch. PMID- 6921968 TI - Perioperative care of the ostomy patient. PMID- 6921969 TI - Microbiological safety index. PMID- 6921970 TI - [Biological effect of environmental exposure to cement dust]. PMID- 6921972 TI - Working with Indians who live on the Gila River Indian Reservation. PMID- 6921971 TI - Unionization and the professional nurse. PMID- 6921973 TI - The nurse and the law. Medical records--a few problems in confidentiality. PMID- 6921974 TI - Myelomeningocele--the spina bifida effect. PMID- 6921975 TI - Everything you wanted to know about nursing. PMID- 6921976 TI - A smooth transition to a tertiary diploma. PMID- 6921977 TI - Reflection and resolution. PMID- 6921978 TI - The politics of nursing. PMID- 6921980 TI - Explanations. PMID- 6921979 TI - The nursing home saga. PMID- 6921981 TI - Philippines: a critical analysis of the nursing profession and the role of unions. PMID- 6921982 TI - Feminism and childbirth. PMID- 6921983 TI - Health promotion: education for the lifestyles of the 80's. PMID- 6921984 TI - Professional care in acute, chronic and terminal illness. PMID- 6921985 TI - Vitamin C: the use of megascorbate therapy in general practice. A clinical experience. PMID- 6921986 TI - Ascorbate (Vit. C) therapy: its role in community health care management. PMID- 6921987 TI - Is natural childbirth dangerous? PMID- 6921988 TI - The nurse's role in restoration to daily living. PMID- 6921989 TI - Hospitals without walls. PMID- 6921990 TI - The clinical nursing facilitator. PMID- 6921992 TI - Responsibility in quality care. PMID- 6921993 TI - Quantitative alterations in the nucleolar and nucleoplasmic ribosomal ribonucleic acids in regenerating rat liver. AB - A quantitative analysis of the nuclear pre-rRNA (precursor to rRNA) and rRNA in normal and 12h-regenerating rat liver was carried out, and the absolute amounts of the identified pre-rRNA and rRNA species in the nucleolus and nucleoplasm were determined. Characteristic changes in the pre-rRNA and rRNA pool sizes in regenerating liver are found which reveal alternations in both pre-rRNA processing and nucleocytoplasmic transition of ribosomes. PMID- 6921994 TI - The major urinary protease inhibitor: simplified purification and characterization. PMID- 6921995 TI - The effects of mevinolin on serum cholesterol levels of rabbits with endogenous hypercholesterolemia. AB - Mevinolin, a fungal metabolite isolated from cultures of Aspergillus terreus, is a potent competitive inhibitor of 3-hydroxy-3-methyl glutaryl coenzyme A reductase, the rate-controlling enzyme in cholesterol biosynthesis. In the current studies we demonstrate that mevinolin significantly lowers serum cholesterol in rabbits fed a cholesterol free, low-fat semi-synthetic diet. Rabbits maintained on this diet developed endogenous hypercholesterolemia with average cholesterol concentrations of 310 mg/dl over a 66-day period. Treatment with mevinolin for 39 days at a dose of 2 mg/kg per day lowered serum cholesterol levels by an average of 37% (P less than 0.05), while a dose of 6 mg/kg per day resulted in a 48% (P less than 0.05) decrease when compared with the control group. When the administration of mevinolin was discontinued, serum cholesterol levels of the 6 mg/kg per day group increased significantly to a maximum post treatment value of 319 mg/dl (P less than 0.0001). The results of this study demonstrate that rabbits with endogenous hypercholesterolemia are a useful animal model for the study of cholesterol biosynthesis inhibitors like mevinolin. PMID- 6921996 TI - Skills training and heterosexual social difficulties. PMID- 6921997 TI - DRO: practical applications to reduce aggressive and disruptive behavior. PMID- 6921998 TI - Let's cool the shop talk. PMID- 6921999 TI - The skill of psychiatric nursing. PMID- 6922000 TI - The CNA connection: caring for the carers. PMID- 6922001 TI - UICC nursing education project: an established and ongoing activity. PMID- 6922003 TI - [Implications of the manpower status for nursing--a future perspective]. PMID- 6922002 TI - [Personnel development for nurses. South Africa and the manpower challenge - a synopsis]. PMID- 6922004 TI - [Personnel development--an orientation]. PMID- 6922006 TI - Some factors influencing the effective use of disinfectants and cleaning agents. PMID- 6922005 TI - The role of the registered midwife. PMID- 6922008 TI - [Music therapy in the education and development of mentally retarded]. PMID- 6922007 TI - [A survey of the experience and conception of illness episodes by a number of senior high school students in a black rural area]. PMID- 6922010 TI - Nursing: an essential expression of human endeavour. Inaugural lecture: the Helen and Morris Mauerberger Chair of Nursing. PMID- 6922009 TI - Primary prevention of physical and mental handicaps: genetic counselling and prenatal diagnosis. PMID- 6922012 TI - [Treat the student nurse as a dignified human being]. PMID- 6922011 TI - Caring for our patients. PMID- 6922013 TI - Isolation of a cationic fragment of high molecular mass kininogen and effect of this fragment on human plasma kallikrein activity. AB - The effect of a cationic fragment of high molecular mass (HMM) kininogen on kallikrein activity and the autocatalytic process of prekallikrein-to-kallikrein conversion were studied. Prekallikrein and kallikrein were obtained by ion exchange and affinity chromatography; the purification of HMM kininogen was achieved using QAE- and DEAE-Sephadex, and separation of the cationic fragment was carried out by gel filtration. It was shown that the fragment of HMM kininogen (mol. mass. 7000, high lysine content) suppressed the activity of a labile form of kallikrein and prevented activation of prekallikrein. A model of the prekallikrein-kallikrein system is proposed. The model is based on the recently established fact of occurrence of two kallikreins and two kallikrein precursors. It involves formation from kininogen, besides kinins, of a kallikrein inhibitor. PMID- 6922014 TI - Effects of frusemide on the renal kallikrein-kinin system of the rat. PMID- 6922016 TI - Home accidents: can they be prevented? PMID- 6922015 TI - Wanted--some good basic statistics. PMID- 6922018 TI - Home accidents. PMID- 6922017 TI - Home accidents: developmental risks. PMID- 6922019 TI - Home accidents: a research project. PMID- 6922020 TI - The turnover of methionine in the Met-tRNA pool and the control of protein synthesis in reticulocyte lysates: no evidence that haem-deficiency promotes deacylation of Met-tRNAf. PMID- 6922022 TI - [Hypodynamia and its control]. PMID- 6922023 TI - [Cerebral complications in arterial hypertension and their treatment]. PMID- 6922021 TI - [Myocardial diseases]. PMID- 6922025 TI - [Prevention of drug allergy]. PMID- 6922024 TI - [Acute delirious and affective-delirious states]. PMID- 6922026 TI - [Health protection and a healthy way of life]. PMID- 6922027 TI - [Complications of acute suppurative otitis media in children]. PMID- 6922029 TI - [New health education films]. PMID- 6922028 TI - [Early conservative treatment of congenital talipes]. PMID- 6922030 TI - [Acute pancreatitis and pregnancy]. PMID- 6922031 TI - [II-stage cancer of the corpus uteri and hemorrhage]. PMID- 6922032 TI - [Speleotherapy]. PMID- 6922033 TI - [Role of the paramedical personnel of psychiatric institutions in conducting treatment and evacuation measures during natural disasters and accidents]. PMID- 6922034 TI - [Epidemiology and prevention of salmonellosis in children]. PMID- 6922037 TI - [Chronic delirious psychoses]. PMID- 6922036 TI - [Principles of the rehabilitative treatment of patients who have had an acute disturbance of cerebral circulation]. PMID- 6922035 TI - [Prevention of cerebral circulatory disturbances in hypertension]. PMID- 6922038 TI - [Syringomyelia]. PMID- 6922039 TI - [Topics for health education talks on the 60th anniversary of the formation of the USSR]. PMID- 6922041 TI - [Inculcation in students of a communist attitude to work]. PMID- 6922042 TI - [Clinically contracted pelvis]. PMID- 6922040 TI - [Health education for prescribed population groups]. PMID- 6922043 TI - [Pathologically anteflexed uterus and algodysmenorrhea]. PMID- 6922045 TI - [Sarcoptic mange: scabies]. PMID- 6922044 TI - [Acute drug-induced hemolytic anemia]. PMID- 6922046 TI - [Organization of psychiatric care]. PMID- 6922047 TI - Hope. PMID- 6922048 TI - The critical care nurse as patient advocate. PMID- 6922049 TI - Using research in practice. PMID- 6922050 TI - Legal issues in nursing. PMID- 6922051 TI - The utilization of AACN standards on a Chapter level. PMID- 6922053 TI - What can you expect as a military nurse? PMID- 6922052 TI - The view from both sides of intensive care. PMID- 6922054 TI - Reduction of depression: three simple interventions. PMID- 6922055 TI - Child death in hospital: the survivor's perspective. PMID- 6922056 TI - [Study on pre-operative information on the medical aspects and prospects of a suggested operation, to be given by the gynaecologist to his woman patients]. AB - Legislation prescribes the doctor's obligation to inform the patient of his situation and prospects before performing an operation. This obligation is of a mandatory character, the only exception being that the patient's life and health should not be seriously jeopardized by such information. The present study was based on questioning 100 woman patients, and it is evident therefrom that such an obligation places too much of a burden on the patient who is unable to cope with the information the doctor is compelled to give. In fact, our results show that frequently patients wish not only to be informed in a factual manner but also expect and desire an optimistic approach to be mediated by the doctor. Hence it appears important to pass on relevant information to the patient in a manner adapted to his personality traits and character. The article demonstrates a model for pre-operative information of this kind to be given to gynaecological patients, and it is shown how justified it is if the doctor demands a wider scope for using his own discretion and judgment in his talks with patients in respect of the information to be given to the patients. Information given by a doctor mainly with the object in mind to legally protect himself against any possible legal consequences, cannot be reconciled with the predominantly altruistic goals of the medical profession. PMID- 6922057 TI - [Studies on the incidence of intracranial haemorrhages and their relation to the delivery by using the cranial computer-tomography (CT) in full-term newborns]. AB - The cranial computer-tomography is a new non-invasive method for the diagnosis of perinatal intracranial haemorrhage. Among 80 neonates, who were examined by CT after delivery at term between the 3rd and 5th day of life, there were 43 newborns without any neurological symptom. These were examined voluntarily with the permission of their parents. A significant correlation between the CT-finding of an intracranial haemorrhage and the neurological observations was found, whereas there was no relation to the mode of delivery. Parity, birth weight, Apgar-score, cord blood-pH did not correspond to the CT-findings. An extremely short duration of the second stage of labor in spontaneous delivery seems to increase the risk of perinatal intracranial haemorrhage. PMID- 6922059 TI - [Ultrasound basic examination during pregnancy]. PMID- 6922058 TI - [Monitoring of foetal movements via real-time ultrasound and their importance for the course of pregnancy]. PMID- 6922060 TI - [Ranking of cerclage in prophylaxis of premature births]. AB - The results of 196 cases after operation for cerclage are reported. In 133 patients the operation was performed because of cervical incompetence with opening of the cervical canal without contractions. In 63 patients a prophylactic operation was performed for anamnestic reasons. In the group of cervical incompetence the operation resulted in 103 (94.5%) deliveries, 12 of which occurred before the 35th week of gestation. Following prophylactic cerclage, 46 (78.0%) pregnancies ended with a delivery. In the latter group, the rate of abortions was four times higher than in the group with cervical incompetence. In 82.6% the birth weight was higher than 2,500 g; 4.7% of the newborn only had a body weight below 1,500 g. Before performing cerclage in the 196 patients the abortion rate had been 50.5%, which dropped subsequently to 11.2%. Childbirth at term could be achieved after operation in 73.2% of the patients, compared to the previous figure of 34.4% only. PMID- 6922061 TI - [Prenatal sex determination via GBN saliva test. A comparison with the results of prenatal chromosomal analysis]. AB - In 114 pregnant women the results of the GBN saliva test were compared with the results of sex determination by prenatal chromosomal analysis. GBN test results predicting boys corresponded in 40,7% of the cases with male karyotypes, whereas test results predicting girls corresponded in 56,5% with female karyotypes. Mean age of the women tested was 35,9 +/- 3,6 years. The test results in women aged 35 or younger did not show a better correlation with the chromosomal sexing than in older women (46,5% and 48,4%). Saliva tests performed in the 16th to 20th week of gestation corresponded to the same extent with the chromosomal sex of the fetuses as those performed in the 21st to 32nd week of gestation (48,5% and 46,2%). The mode of ascertainment of the pregnant women and other factors possibly influencing the results are discussed. It is concluded that the GBN saliva test is not suitable for prenatal sex prediction in women of the age group investigated. PMID- 6922062 TI - [The problem of extirpation of gonads in "testicular feminisation"]. AB - The 15-year old female patient G. G. was referred to the outpatient department for child gynaecology on account of a primary amenorrhoea. The endocrinal parameters found (testosterone, oestradiol, 17 OHCS, 17 KS), chromosome analysis, vaginoscopy and the result of a laparoscopy led to the clinical diagnosis of "testicular feminisation". Satisfactory development of secondary female sex characteristics and sudden increase of complaints caused by an inguinal hernia on the left (gonad situated in the inner inguinal ring) prompted us to perform bilateral extirpation of gonads with simultaneous treatment of the inguinal hernia. Histological examination revealed the existence of a seminoma of the right gonad. This case confirm our stand in respect of extirpation of gonads at the onset of puberty, but it also raised the question as to whether it would be advisable to operate at an even earlier stage in order to avoid the risk of malignant degeneration of intra-abdominally positioned testes. PMID- 6922063 TI - [New results in connection with the problem of a connection between oral contraception and vaginal yeast]. PMID- 6922065 TI - [Urinary ascites secondary to ureteroperitoneal fistula]. PMID- 6922064 TI - [Therapy of mammary cysts with 2 alpha-bromergocryptine]. PMID- 6922066 TI - [False intrauterine amniotic sac in ultrasonographic diagnosis of extrauterine pregnancy]. PMID- 6922067 TI - [The position of the IUD and intrauterine pregnancies]. AB - In 59 women who became pregnant with an IUD the position of the device was controlled by ultrasound. Before the 9th week of pregnancy the device was located in 40 women (78.4%) in the cervix or in the isthmic region of the uterus. In 11 cases the IUD was in correct position. 8 women had a pregnancy of more than 9 weeks and were not included in the study as the gestational sac could have influenced the IUD position. The possibility of regular control of the IUD position by ultrasound is discussed in order to reduce the failure rate of this contraceptive method. PMID- 6922068 TI - [Possible prognostic criteria for the improvement of the treatment of primary carcinoma of the breast]. PMID- 6922069 TI - [Diagnostic and therapeutic management of breast cysts]. AB - In a study of 144 patients with cystic dysplasia of the breast diagnostic and therapeutic accuracy of palpation, mammography, aspiration cytology and pneumocystography was investigated. Only in 9.7% of the cases a surgical biopsy was necessary. In more than 90% of the cases biopsy was not performed; instead of this follow up with palpation, mammography and aspiration cytology up to 11 months was done. No breast cancer was overlooked, three of four proliferating dysplasias were detected. In 21% a local cystic recidive occurred which again was punctured. In contrary to surgical biopsy follow up of cystic dysplasias is not complicated by scars and their diagnostic problems. No complications were seen. PMID- 6922070 TI - [Expected results from reduction mammoplasty of the female breast (retrospective studies on 83 women after reduction mammoplasty without signs of cancer)]. PMID- 6922071 TI - [Multiple tumors in cancer of the uterine corpus]. AB - Out of 808 (100%) cases of endometrial carcinomas, registered at the Klinik Bad Trissl during a period of 14 years (1968-1981), over 85 cases (10,5%) of double and triple malignomas were found. 59 cases (7,3%) are correlated with a second primary breast cancer, 26 (3,2%) with other primary malignomas. 9 cases (1,1%) show triple malignomas. 5 precancerous cases (0,6%) were included in the survey. Contrary to medical literature the survey reveals a different distribution of neoplasms among the affected organs. PMID- 6922072 TI - [Clinical aspects and therapy in primary ovarian cancer]. AB - The charts and the histological slides of 122 cases of ovarian cancer, treated at the 2nd Gynaecological Department, University of Vienna, in the years 1968 to 1977 were reexamined. The statistic evaluation were done by Pearson's correlations coefficient, the Breslow and Mantel test or the trend test after Tarone. Priority was given to the prognostic value of all the data gathered. Problems of presurgical diagnosis and symptoms were outlined. The 5 years survival rate was in stage I 73%, in stage II 25% and in stage III 5%. The survival curves of stage Ia and Ib did not show any differences wether the adnexa had been removed or total exstirpation had been performed. The presence of ascites however impaired the prognosis significantly. In almost all cases of stage II total exstirpation had been performed. In stage III no significantly different effects could be observed between "incomplete" surgery as probatoria, exstirpation of the inflicted adnexa and total exstirpation of the internal genitals. Therefore an additional total omentectomy seems to be obligatory for further improvement of survival curves. A significant improvement of the survival rates has been achieved by telecobalt irradiation. PMID- 6922073 TI - [Urodynamic evaluation of the effect of neural therapy in motor and sensory urgency]. AB - We treated 10 patients with motor or sensory urgency by paraurethral injection of a local anesthetic. After clinical and urodynamic work-up we applied 2.5 ml of 1% lidocain solution with Kollidon to delay absorption (Xyloneural) transvaginally to the right and left of the urethro-vesical junction. Each treatment cycle consisted of 3 injections with 2-week intervals between injections. 2 weeks after the last injection a repeat urodynamic investigation was done. All patients were improved by therapy: after the 3rd injection 3/10 women were free of symptoms, 6/10 women reported marked improvement, and one woman slight improvement of the symptoms of urgency and frequency. The mean bladder volume at the first sensation to void increased significantly after neural therapy (p = 0.02); other urodynamic parameters were not affected by neural therapy. No side effects were observed. We conclude that the paraurethral injection of a local anaesthetic is a simple and effective treatment in motor and sensory urgency. PMID- 6922074 TI - [In-vitro fertilization of human eggs and embryo transfer]. AB - This is a first report on experience with in-vitro fertilization of human eggs and embryo transfer. The follicle was aspirated to obtain eggs in 24 patients. A successful fertilization of the oocytes with obvious formation of a pronucleus was observed in 3 cases. In 9 more cases cell divisions were obtained and the embryos were transferred at the 4-cell stage. In spite of the unfavourable female patient population a good fertilisation and embryo transfer rate was achieved. PMID- 6922075 TI - [Fertility with uterine anomalies]. AB - 45 patients with uterine anomalies were studied regarding their fertility. 39 of these 45 patients were pregnant prior or following the diagnosis. The 80 conceptions show a fertility rate of 86.6%. 46 pregnancies led to the delivery of a viable infant. 34 pregnancies resulted in miscarriage of premature delivery. Miscarriages were much more frequent in women with bicornuate or unicornuate uteri (60%). When other possible reasons for abortions such as toxoplasmosis, insufficiency of the cervix or deficient luteal phase are corrected the number of pregnancies rose to 82. In 53 of these cases a viable infant was delivered. 30% of the women had to be delivered by Caesarean section. When the desire for child bearing exists uterine anomalies need to be first treated conservatively. Surgical correction of the anomaly is only indicated in a limited number of these cases. PMID- 6922076 TI - [The cardiac hazard of tocolysis and antagonizing possibilities. II. Communication: protection of the myocardium by means of substitution of magnesium]. AB - In a comparative study the value of the substitution of magnesium for the evaluation of cardiac side-effects of tocolysis has been assessed with regard to haemodynamic as well as to metabolic and morphologic alterations. Haemodynamic studies at the thoracotomized dog using the technique described in the first publication showed significantly less severe haemodynamic alterations in a group with normal magnesium blood levels than in the second group with reduced magnesium blood levels. Significant differences could be found at systolic blood pressure, cardiac output, velocity and acceleration of pressure rising, total peripherial resistance, myocardial contraction status and myocardial oxygen consumption. Likewise, a beneficial tendency could be found at the parameters: heart rate, Bretschneiders index of inotropy, pulmonal arterial pressure and coronary reserve. During chronic experiments at the rat, the addition of magnesiumaspartate led to a significantly improved preservation of high-energy phosphates in the myocardium with a concomitant reduction of lactic acid output. Also the increase of body weight was significantly higher when substituting magnesium. Microscopic examination showed no irritations of myocardial structure within the magnesium-substituted group, whereas lymphocytic infiltrations and a slight fibrosis of the endocardium could be seen at the animals having received only Fenoterol. Together, these findings lead to the conclusion, that the substitution of magnesium can act prophylactically against cardiac alterations, induced by Fenoterol. Consequently, magnesium deficiency, which frequently accompanies pregnancy, should be balanced before starting a tocolytic therapy. PMID- 6922077 TI - [Diagnosis of intra-uterine growth retardation by intensive ultra-sound biometry]. AB - In a prospective study on 125 maternity patients with suspected intra-uterine growth retardation, simple ultrasound biometry (measuring of the distance) and intensive ultra-sound biometry (measurement of the circumference and the surface) were compared. Of 85 newborn born within two weeks following the biometry 34 newborn had intra-uterine growth retardation with a weight percentile smaller than 5, and 32 newborn were growth retarded with a percentile of 5-10. In 19 cases no growth retardation was found. (12 newborn in this group had a weight percentile 10-25). The measurement of the biparietal diameter was capable of diagnosing at the most 50% of the growth retardations (percentile under 5). The accuracy of the diagnosis of intra-uterine growth retardation increased to 85% with the thoraco-abdominal transverse diameter. The so-called borderline cases (percentile 5-10) were diagnosed with the bi-parietal diameter in 38 percent of the cases and by the transverse thoracic diameter in 41% of the cases. Measurement of the circumference of the head resulted in no better measurements than the bi-parietal diameter. The addition of the measurement of the thoracic circumference increased the diagnosis of severe fetal growth retardation (percentile under 5) to 90% and in borderline cases to 88%. The head thorax index and the ratio of head circumference and thoracic circumference increase in our investigation the accuracy of the diagnosis of intra-uterine fetal growth retardation substantially. PMID- 6922079 TI - [On diagnosis of acardius in pregnancy by ultra-sound]. PMID- 6922078 TI - [Myoglobinuric myopathia in the third trimester of a twin-pregnancy]. PMID- 6922080 TI - [Sterilization of mentally retarded women]. AB - Seven mentally retarded women were sterilized in the Department of Obstetrics and Gynaecology of Medical School Hannover between 1.6.74 and 1.6.81. The decision to operate proceeded only after careful consideration by the director of the clinic. Each case was documented with proof that improvement of the mental situation was unprobable and that sterilization seemed highly desirable. In spite of strong reservation the sterilization of a mentally retarded may medically and ethically be justified in exceptional cases. The operation seems possible by the following: The sterilization may only be performed if the patient does not obviously refuse it. Diagnosis and prognosis of the mental handicap must undoubtedly be proven. If the patient cannot judge the consequence of the operation the legal guardian must decide for her. The court must consent in these cases. Regarding legal theory the decision by the guardian is an open question. PMID- 6922081 TI - [The effect of preoperative information by a booklet on patients in gynaecology]. AB - 300 patients who had given their "Informed Consent" to surgery after reading the booklet "Operationen in der Frauenheilkunde" received questionnaires. 172 of 179 replies came to evaluation. The content of the booklet was judged as well balanced by 154 patients (90%), as too short by 7 (4%), as too detailed by 11 (6%). 77 patients (45%) were calmed by the booklet, 47 (27%) were disturbed, 48 (27%) were not influenced. Not any patient took the booklet for more important than the informative talk with the doctor. Both elements of preoperative information have the same value in the opinion of 105 patients (61%), 21 (12%) gave a slight, 46 (27%) a definite preponderance to the talk with their doctor. Very little advantage from the booklet had those patients, who judged its content as too short or too detailed. 95 patients expressed their opinion concerning the reason that makes a doctor distribute the booklet to his patients previous to surgery. The results of this investigation prove an overall positive reception of the booklet "Operationen in der Frauenheilkunde" as an instrument of preoperative information. PMID- 6922083 TI - Look it up! Building a reference library. Part I. PMID- 6922082 TI - Comparison of immunological and enzymatic properties of human urinary and pancreatic kallikrein. AB - Human urinary and human pancreatic kallikreins were compared by radioimmunoassay, immunoelectrophoresis, by their enzymatic activity using the substrate Ac-Phe-Arg OEt and by their biological activity employing the dog blood pressure assay. The only significant difference observed was a higher anodal mobility of the urinary kallikrein under the conditions of immunoelectrophoresis. PMID- 6922084 TI - Get the facts on Agent Orange. PMID- 6922085 TI - Coping with academic stress. PMID- 6922086 TI - Pain relief: more than only a hand(hold) away: the importance of touch in patient care. PMID- 6922088 TI - Modulation of classical C3 convertase of complement by tear lactoferrin. AB - Lactoferrin isolated fom normal human tears was shown to inhibit the complement mediated lysis of antibody-coated red cells. The anti-complementary effect of lactoferrin on serum complement could be reversed by adding Fe3+ but not by Mg++ or Ca++. Lactoferrin did not inhibit the formation of EAC14 but markedly blocked the assembly of the EAC142 enzyme. Once the C3 convertase was formed lactoferrin did not affect the function of the enzyme and only had a minor effect on the intrinsic decay of C2 from the convertase. Inhibition of the C3 convertase formation was not seen by preincubating EAC14 intermediates with lactoferrin, but only occurred when lactoferrin and C2 were incubated together with EAC14 cells. Our findings suggest that lactoferrin may play an anti-inflammatory role by modulating activation of the complement system. PMID- 6922087 TI - Digestion and resynthesis of receptors binding IgG-sensitized erythrocytes on rat macrophages. AB - The proteinase sensitivity of rat macrophage Fc receptors (FcR) binding rabbit IgG-sensitized sheep erythrocytes (EA) was analysed by incubating alveolar macrophages with trypsin, alpha-chymotrypsin, pronase, granulocytic elastase and inhibitors of protein biosynthesis. Even under conditions at which enzymes alone did not bring about any receptor degrading effect, a reduction of cycloheximide. After a temporary blockade of protein biosynthesis by cycloheximide of macrophages which had lost their FcR through treatment with pronase, a rapid reappearance of EA-binding activity could be observed when the cells were washed and incubated in medium without drug or enzyme. On the other hand, the blockade induced by actinomycin D could not easily be reversed. The rate of reappearance of EA-binding activity of alveolar macrophages (AM psi) was faster than that of peritoneal macrophages (PM psi). Our results may suggest an alternative explanation for the apparent resistance of receptors to proteolytic digestion. The finally observed result may be caused by re-expression of FcR--either newly synthesized or from an intracellular pool--as well as by an inaccessibility of the receptor to the enzyme. PMID- 6922090 TI - Floor disinfection in the United States. PMID- 6922089 TI - Isolation and characterization of pneumolysin-negative mutants of Streptococcus pneumoniae. AB - Pneumolysin-negative mutants of Streptococcus pneumoniae were isolated after mutagenesis with ethyl methane sulfonate. Though totally devoid of pneumolysin, these strains produced alpha hemolysis on blood agar when incubated aerobically. It is concluded that the alpha hemolysis typical of pneumococci is unrelated to their pneumolysin content. PMID- 6922091 TI - Pneumococcal immunization: strategies for implementation. PMID- 6922092 TI - Pneumococcal infections and pneumococcal vaccine: an update. AB - Pneumococcal pneumonia continues to be an important disease in terms of prevalence, morbidity and mortality. With the discovery of penicillin and its wide clinical use, the overall mortality of pneumococcal pneumonia has been significantly reduced, but problems remain. These include: 1) death rate is uninfluenced by the antibiotic in the first five days of illness; 2) death rate in certain high risk groups and in patients infected with type 3 pneumococcus exceeds 25%; and 3) penicillin resistant strains of pneumococci have emerged. Because of these and other considerations, a modern 14-valent pneumococcal vaccine has been developed by Robert Austrian and his co-workers. The vaccine has been found to be immunogenic and effective in a number of populations studied. Additional efficacy studies are needed, however, particularly in certain high risk groups, such as the elderly and immunocompromised patients. PMID- 6922093 TI - Hospital-based pneumococcal immunization: the epidemiologic rationale and its implementation. AB - Many patients hospitalized for or dying of pneumococcal bacteremia have been discharged from a hospital within the previous five years. In addition to age and underlying medical condition, previous hospital care, particularly for high risk conditions, is a useful marker for identifying individuals who are destined to develop serious pneumococcal infections. Relatively few patients, especially those with high risk conditions, would need to receive pneumococcal vaccine at the time of hospital discharge to prevent, within the next five years, each subsequent readmission or death from pneumococcal pneumonia. Although pneumococcal vaccine has not been widely used in the hospital setting, there are sound epidemiologic reasons to expect that organized programs for vaccine delivery in hospitals would be an effective approach to preventing many serious pneumococcal infections. PMID- 6922094 TI - Pneumococcal immunization: policy development and implementation from the ACIP perspective. AB - The Advisory Committee on Immunization Practices (ACIP) of the U.S. Public Health Service is responsible for making recommendations on the use of new vaccines and periodically revising those for established vaccines. Recommendations for pneumococcal vaccine were first issued in 1978 and revised in 1981. The changes which appear in the revision reflect the continuing maturation of the Committee's judgment on the vaccine and are a good example of the process by which the ACIP develops its recommendations on national immunization practices. PMID- 6922095 TI - Pneumococcal immunization: strategies for implementation, a discussion. PMID- 6922096 TI - The consultant role in multidisciplinary team development. PMID- 6922097 TI - Strategies for implementation of a new curriculum in Nigeria. PMID- 6922098 TI - The impact of mutilating surgery or trauma on body-image. PMID- 6922099 TI - Be informed - be active. PMID- 6922100 TI - The sacrament of the anointing of the sick : theology. PMID- 6922101 TI - Death-related fears. PMID- 6922102 TI - The role of the psychiatric nurse consultant on a burn unit. PMID- 6922103 TI - Life events, method of coping, and interpersonal trust: implications for nursing actions. PMID- 6922104 TI - The concept of assertion: from theory to practice. PMID- 6922105 TI - Sexism in child care. PMID- 6922106 TI - A community experience programme for student nurses in Jersey. PMID- 6922107 TI - Organizing community experience for student nurses in Northamptonshire. PMID- 6922109 TI - Weaning - do health visitors give consistent advice? PMID- 6922108 TI - How I became a breast feeding counsellor with the National Childbirth Trust. PMID- 6922110 TI - A Florence Nightingale for the Third World? PMID- 6922111 TI - Contraception in ethnic minority groups in Bedford. PMID- 6922112 TI - Some observations on Gujarati diet and pregnancy. PMID- 6922113 TI - Understanding Vietnamese in Britain. Part 1: Background and family life. PMID- 6922114 TI - Mother and toddler groups among 'at risk' families. PMID- 6922115 TI - Postnatal group for mothers with serious mothering problems. PMID- 6922116 TI - Parents as partners. PMID- 6922117 TI - 'Nurse, why are the kids always getting nits?". PMID- 6922118 TI - Understanding the Vietnamese in Britain. Part II: Marriage, death and religion. PMID- 6922119 TI - A research base for humane care: hospitalized children and their families. PMID- 6922120 TI - Nursing management of the child in status epilepticus. PMID- 6922121 TI - Neonatal death: parental evaluation of the NICU experience. PMID- 6922122 TI - The adolescent and systemic lupus erythematosus: a developmental and educational approach. PMID- 6922123 TI - Breast-feeding. PMID- 6922124 TI - Special section: children and pain. PMID- 6922125 TI - Pain theories and their relevance to the pediatric population. PMID- 6922126 TI - The assessment of pain in children. PMID- 6922127 TI - Measuring children's self-assessment of pain. PMID- 6922128 TI - Coping strategies of children in pain. PMID- 6922129 TI - Minimizing pain associated with prekindergarten intramuscular injections. PMID- 6922130 TI - Description of the pain experience: a study of school-age children. PMID- 6922131 TI - Studies on the high molecular weight form of polypeptide chain elongation factor 1 from pig liver. II. Interaction with guanine nucleotides and aminoacyl-tRNA. AB - The high molecular weight form of polypeptide chain elongation factor-1, or EF 1H, has been purified from pig liver to apparent homogeneity and shown to be a 1:1:1 complex of EF-1 alpha, EF-1 beta, and EF-1 gamma, namely, EF-1 alpha beta gamma (Hattori, S. and Iwasaki, K. (1980) J. Biochem. 88, 725-736). Therefore, its enzymatic properties were investigated in detail. The effects of various components such as NH4Cl, Mg(CH3COO)2, guanine nucleotides and Phe-tRNA on its heat stability were investigated and it was found that its properties were very close to those of the aminoacyl-tRNA binding enzyme from rabbit reticulocytes (McKeehan, W.L. and Hardesty, B. (1969) J. Biol. Chem. 244, 4330-4339). Furthermore, it was reported that EF-1 alpha beta gamma seemed to dissociate into EF-1 alpha and EF-1 beta gamma when guanine nucleotides were present, and also to form a complex of EF-1 alpha . GTP . [14C]Phe-tRNA when both GTP and [14C]Phe tRNA were present. On the contrary, however, when the interaction between EF-1 alpha beta gamma and guanine nucleotides was analyzed by gel filtration at 4 degrees C, the dissociation of EF-1 alpha beta gamma could not be detected, instead the formation of binary complexes containing EF-1 alpha beta gamma and guanine nucleotides was observed. The dissociation constants of the EF-1 alpha beta gamma . GDP and EF-1 alpha beta gamma . GTP complexes were estimated to be 6.8 x 10(-6) M and 7.3 x 10(-6) M, respectively, and the number of binding sites per molecule of EF-1 alpha beta gamma for these nucleotides was estimated to be one. Little, if any, interaction was detected between EF-1 alpha beta gamma and aminoacyl-tRNA even in the presence of GTP. The controversial results obtained by different methods as described above seemed to be compatible with each other, if one assumes that the dissociation constant for the conversion of EF-1 alpha beta gamma into EF-1 alpha and EF-1 beta gamma increased with the increase in temperature. When gel filtration of EF-1 alpha beta gamma was carried out with a solution containing both GTP and [14C]Phe-tRNA, the formation of a ternary complex containing EF-1 alpha, GTP and [14C]Phe-tRNA was detected at 4 degrees C, although the amount was very small. From these results, we assumed that EF-1 alpha beta gamma interacts with GTP and aminoacyl-tRNA (aa-tRNA) according to the following sequences; EF-1 alpha beta gamma + GTP in equilibrium with EF-1 alpha beta gamma . GTP EF-1 alpha beta gamma . GTP in equilibrium with EF-1 alpha . GTP + EF-1 beta gamma EF-1 alpha . GTP + aa-tRNA in equilibrium with EF-1 alpha . GTP . aa-tRNA. PMID- 6922132 TI - The gene for a spinach chloroplast isoleucine tRNA has a methionine anticodon. AB - The nucleotide sequence of the gene for spinach chloroplast tRNAIle1 has been determined. The gene is found in two copies located in the inverted repeat regions of spinach chloroplast DNA, but not within the ribosomal RNA spacer. Both copies of the tRNAIle1 gene have been sequenced and found to be identical. A very unusual characteristic of the tRNAIle1 gene is that the anticodon is CAT which is a methionine anticodon. In the tRNA the C residue in the anticodon is subsequently modified, presumably to prevent misreading of the genetic code. The spinach chloroplast tRNAIle1 gene is colinear with its RNA sequence and does not contain an intervening sequence as has been reported for maize chloroplast tRNAIle2 (Koch, W., Edwards, K., and Kossel, H. (1981) Cell 25, 203-213). The tRNAIle1 gene does not code for the 3'-terminal CCA end, nor do any other tRNA genes appear to be contiguous with this gene. PMID- 6922134 TI - Setting the pace: new approaches in nursing practice. PMID- 6922133 TI - Methicillin-resistant-Staphylococcus aureus colonization and infection in a rehabilitation facility. AB - Methicillin-resistant Staphylococcus aureus (MRSA) colonization and infection in a rehabilitation hospital (Rancho Los Amigos Hospital [RLAH]) were studied from October 1977 to May 1980. Eighty-four episodes of MRSA colonization or infection were observed in 81 patients (attack rate, 0.44 per 100 admissions). The MRSA was considered to have been acquired at RLAH in 65% of the episodes and from transferring hospitals in 34%. The infection rate was 35% among MRSA-colonized patients, and only one death was attributed to MRSA infection. Colonization for more than 100 days occurred most frequently in wounds and anterior nares. All but two of the MRSA isolates were resistant to aminoglycosides, and 80% of those typed belonged to phage type 83A. The patients were allowed to continue participation in rehabilitation programs. Spread of the MRSA occurred in wards where intensive medical and nursing care was being practiced. There was no evidence of MRSA spread in the services with less intense medical and nursing care and where physical and occupational therapy was continued. Patients in a rehabilitation hospital with MRSA colonization may receive intensive physical and occupational therapy as long as special precautions are observed to prevent MRSA spread. PMID- 6922135 TI - The role of the nursing profession in hospital accident and emergency departments. AB - A major investigation in the North West region has aimed to ascertain attitudes towards, and expectations of, accident and emergency services among both client groups and professionals involved in the provision of the services. One element of the research has focussed on a questionnaire based survey among 260 nurses in nineteen hospital accident and emergency (A & E) departments. The results show that the nurses found their work to be interesting and satisfying and they enjoyed the challenge of a varied and unpredictable workload. They expected to deal with patients in need of urgent medical attention, and to use and develop their nursing skills and experience. On the whole, their expectations were met, although they were not very satisfied the the levels of cooperation from other hospital departments, their liaison with community services, and the amount of time which casual attenders with minor/non-urgent conditions occupied. The nurses were, however, generally sympathetic towards all A & E patients although they believed that many came for reasons of convenience and ignorance and that the general public need more education with regard to the appropriate use of an A & E department. PMID- 6922136 TI - "The nurse should consider.' Critical care ethical issues. AB - A hypothetical dilemma on resuscitation of an intensive care patient was presented to nurses at a workshop on ethics of critical care nursing. Nurses responded to separate questionnaires about what a charge nurse should do, and what they themselves would do in relation to ten considerations arising from the dilemma. Nurses were agreed that legal consequences, patient wishes and rights, and physician authority should and would be considered, and that peer influence should not. Nurses were divided in their attitudes to following procedure and personal moral beliefs, and to job risk. The most contentious issues were related to the nurse's role as a decision-making member of the health care team. Implications for regarding nurses as independent decision-makers are discussed. PMID- 6922137 TI - Clinical teaching: an evaluation of a problem orientated approach to psychiatric nurse education. AB - In a recent paper by one of the authors (Cormack 1080) the use of the problem orientated approach to nursing, and a proposed framework for assessing nursing needs, were discussed. Subsequently one of the writers (W.R.) utilized the problem orientated approach during the psychiatric nursing experience made available to student nurses undergoing the comprehensive modular training at the Highland College of Nursing and Midwifery, Scotland. This paper presents an evaluation of the problem orientated approach which has now been developing for 2 years. This paper describes the experience of W.R. in using a problem orientated approach to nursing diagnosis and nursing care prescriptions. It is argued that such an approach, combined with patient-centred rather than classroom based nurse education, is essential to enable psychiatric nurse teachers to teach effectively. Such a patient-centred approach is also necessary to clarify the psychiatric nurses' role and to shift the emphasis of psychiatric nurse education away from psychomotor skills to interpersonal skills. While it is recognized that this evaluation does not comply with the scientific criteria of a formal research based project, it is suggested that the experience of the authors and the comments of the many students involved in the exercise accurately reflect the problems encountered and the progress achieved. PMID- 6922138 TI - The effects of brief psychiatric training on the attitudes of general nursing students to psychiatric patients. AB - The attitudes of an unselected sample of general nursing students to a series of matched medical and psychiatric case-examples were assessed before and after they received 9 weeks training in either a general hospital psychiatric unit or a geriatric unit. The major component in cluster analyses of construct ratings of case- descriptions by both groups before and after training was a factor of fear, or distrust, on which students differentiated clearly between medical and psychiatric cases, tending to expect the psychiatric patients to be more frightening, less likely to cooperate, more likely to be violent and dangerous and to need strict control. Psychiatric training, therefore, did not eliminate students' distrust of psychiatric patients. This highlights the importance, during training, of attending to issues of trust and responsibility, and the problems of fear and prejudice caused by psychiatric labels. The attitudes of permanent psychiatric staff are highly relevant in considering how students will be affected by psychiatric work experience. Some benefits of contact with psychiatric patients were found, and the implications of these are discussed. These benefits support the value of the training experience, overall, and it is suggested that students should work with psychiatric patients earlier in their course (in the first year). The scope of psychiatric training should be broadened and improved to make this a more attractive, worthwhile option. PMID- 6922139 TI - Problems in teaching ethnic minority nursing students. AB - Ethnic minority nursing students are different from the majority of white students, and approaches that nursing faculties use in teaching them must also be different. Teaching these students is sometimes viewed by many faculties as a threat. However, if difficulties are recognized early and handled efficiently, educating the ethnic minority students can instead become a challenge to the nurse educators. The authors propose some ways to deal with the existing or potential difficulties that arise from teaching these students. These suggestions are made with major emphasis on the student, the teaching process, and the curriculum. Ethnic minority students need to be helped to develop a positive self esteem, a sense of worthiness and a feeling of equality and acceptance. Nursing faculties are charged with this responsibility and must be committed to it. Furthermore, nursing curricula need to take into account cultural diversity, to increase students' understanding of the impact of cultural diversities on health care. This paper presents a viewpoint from which important questions related to problems associated with teaching minority students, could be raised. PMID- 6922140 TI - Workshops in personal relationships. AB - This paper describes the planning, implementation and evaluation of a series of workshops for practising health visitors, as one aspect of continuing professional education. The history demonstrates response to stated need. Planning was intensive and extensive, resulting in one broad educational objective and a flexible approach to teaching/learning, contributions of expertise from several disciplines proved valuable. Prior to full implementation, experimental workshops were organized and evaluated both objectively and subjectively. The variety of methods of evaluation permitted isolation of some factors which mitigate against success and their avoidance when possible. The objective evaluations used three criteria which appeared to demonstrate positive outcomes to a great extent. Evaluations of 17 workshops demonstrate the continuing value of this form of education, and the summarized response shows, inter alia, that impetus does not necessarily reduce with time. Of significance is the evidence that the results include improved professional practice and that there were increases in depth and breadth of knowledge. Additionally, there were developments of self-help and professional interest groups. Finally, the sequel should lead towards a model of training resource personnel within the NHS, the trial of the model being early in 1982. PMID- 6922141 TI - Janforum. Nurse/patient dependency revisited (somewhat apologetically). PMID- 6922143 TI - Combating 'burn-out' by developing a theoretical framework. PMID- 6922142 TI - Biosynthesis of a structurally abnormal C2 complement protein by macrophages from C2-deficient guinea pigs. AB - In order to characterize a genetic deficiency of C2 in guinea pigs, production of C2 by peritoneal macrophage cultures derived from four normal, four heterozygous deficient, and four homozygous deficient animals was measured functionally and immunochemically after metabolic labeling with 35S-methionine. Macrophage monolayers from homozygous deficient animals failed to secrete hemolytically detectable C2 up to 74 hr in culture. A single cell hemolytic plaque assay also failed to demonstrate any functional C2 production by cells from homozygous deficient animals. No C2 protein was detected in media from three of the four homozygous deficient animals, but in one, apparent C2 fragments were present. In contrast, intracellular C2 protein was identified in all four homozygous deficient cell cultures. Its mobility on SDS-PAGE was slightly faster than normal. Much less abnormal intracellular C2 protein was recovered from homozygous deficient macrophage monolayers than intracellular C2 protein from normal macrophage monolayers. Monolayers from heterozygous animals produced functional and immunochemical C2 at approximately 30% of the normal rate. Normal rates of biosynthesis and secretion of two other MHC-linked class III antigens, C4 and factor B, were detected in macrophage cultures from homozygous and heterozygous deficient animals. These data suggest that a specific defect, i.e. a structural abnormality in C2 protein, underlies C2 deficiency in guinea pigs. PMID- 6922144 TI - Nursing diagnosis research. PMID- 6922145 TI - Acute mood and behavior disturbances of neurological origin: acute confusional states. PMID- 6922146 TI - Landry-Guillain-Barre-Strohl syndrome. PMID- 6922147 TI - Progressive multifocal leukoencephalopathy. PMID- 6922148 TI - The diagnosis of brain death: overview of neurosurgical nursing responsibilities. PMID- 6922150 TI - 1982 Presidential address: 14th Annual AANN Meeting. PMID- 6922149 TI - A comparison of four holding devices for anchoring nasogastric tubes. PMID- 6922151 TI - Arnold Chiari malformation. PMID- 6922152 TI - The total patient: implications for nursing care of the epileptic. PMID- 6922154 TI - The effects of congenital rubella on the neonate. AB - Asymptomatic rubella occurring in mothers may be mild or clinically unapparent, yet cross the placental barrier. The Baylor Group, through intensive clinical and virological studies, led the country in the identification of an expanded CRS. The group concluded that congenital heart, ear, eye, and CNS structural involvements were the result of especially acute manifestations of ordinary congenital rubella. Neurological disorders of the neonate previously ascribed to unknown etiologies were found to be secondary to rubella encephalitis. The ongoing occurrence of sub-acute maternal rubella may therefore be responsible for innumerable cases of neurological deficiencies in the neonate. Although immunization against rubella was not effective until after the actual outbreak of the 1964 epidemic, the Baylor Group served to decelerate a health crisis through rapid, coordinated efforts. Alerted to the possibility of a more diverse CRS, the group prevented prolongation of the epidemic with appropriate treatment of infected neonates. PMID- 6922153 TI - Hypotonia in infants and children. AB - Many diseases in the pediatric population present with hypotonia and/or weakness. In order to ensure proper diagnosis and facilitate appropriate treatment, the nurse must be familial with those diseases which produce motor unit dysfunction in infants and children; among these conditions are infantile botulism and Guillain-Barre Syndrome. An understanding of the particular features which distinguish central from peripheral hypotonia is essential for the nurse. It is also important to obtain detailed histories and to ensure thorough physical examination. The nurse should also be aware of those laboratory studies that evaluate hypotonia and weakness, including the EMG, PNCT, muscle biopsy, and lumbar puncture. PMID- 6922155 TI - So you're the inservice educator on a Neuro Unit..... PMID- 6922156 TI - Preventing stroke through non-invasive carotid artery assessment. PMID- 6922158 TI - Informed consent--the informed neurosurgical patient and family. PMID- 6922157 TI - Radiofrequency lesions--a treatment for trigeminal neuralgia. PMID- 6922159 TI - Drug stop: migraine headache. Current therapy. PMID- 6922160 TI - The unification of midwives: a time of dialogue. PMID- 6922161 TI - A nurse-midwifery approach to early mother--infant acquaintance. PMID- 6922163 TI - The future of midwifery--an alliance. PMID- 6922164 TI - Su Clinica Familiar--Georgetown University pilot project. PMID- 6922165 TI - The Oxford lactation study. PMID- 6922162 TI - American childbirth educators in China: a transcultural exchange. PMID- 6922166 TI - Puerperal inversion of the uterus: a case report. PMID- 6922167 TI - Nurse-midwifery education--the second 50 years. PMID- 6922168 TI - SPANS--bridging the gap between SPNs and LPNs. PMID- 6922169 TI - Belong and be strong! PMID- 6922170 TI - Responsibilities of the LPN. PMID- 6922173 TI - When the practical becomes theoretical. PMID- 6922171 TI - What does the future hold for LP/VNs? PMID- 6922172 TI - Erythromycins. PMID- 6922174 TI - Role strain and depression: a causal inquiry. PMID- 6922176 TI - Nurses and disasters. PMID- 6922175 TI - Teaching interpersonal skills: a model for facilitating optimal interpersonal relations. AB - This article draws upon the results of a series of studies involving observations of interviews involving psychiatric patients and their friends, and between psychiatric patients and nurses. A two-dimensional structure of interpersonal behavior is described. Three principles of effective interpersonal relations are detailed, including interpersonal complementarity, interpersonal versatility, and interpersonal influence. Research results that indicate how psychiatric patients have trouble exercising these principles are reported. A three-phased assessment, intervention, and reassessment approach to facilitating interpersonal skills in patients is detailed. A counselor-teacher approach to the treatment of psychiatric patients is recommended. PMID- 6922177 TI - Name that feeling! An innovative teaching tool. PMID- 6922179 TI - Nurses' burnout: lack of positive conditions and presence of negative conditions as two independent sources of stress. PMID- 6922180 TI - Psychiatric day programs: a descriptive analysis. AB - Partial hospitalization programs evolved as a result of a variety of financial, social and therapeutic circumstances. At present, these programs can take one of several different forms. Of these, the most common ones are the three day programs--day hospital, day treatment, and day care. In theory, each of the three would serve a distinct population, have a clearly defined structure, and be administered in a predictable manner. This article contrasts theory with practice and makes an analysis of the actual and potential effectiveness such as demographics and economics are presented. Recommendations for the present and future follow from projected long range shifts and trends. PMID- 6922178 TI - Research studies in American Indian suicides. PMID- 6922181 TI - A family approach to the battered woman. PMID- 6922182 TI - Mental health problems of Vietnam veterans. PMID- 6922183 TI - Schizophrenia: current diagnostic concepts and implications for nursing care. PMID- 6922184 TI - Foster care, adoption and the grief process. PMID- 6922185 TI - Observations on maternal dietary fat intake and fetal pulmonary maturation in rats. AB - Pregnant rats were maintained on one of the following dietary regimes: (1) low fat through gestation; (2) low fat to gestational age 15, then high fat until term; or (3) high fat throughout gestation. Fetal pulmonary maturation (as measured by the lung content of acetone-precipitable lecithin) was accelerated in rats on the high-fat diet, was intermediate in the group on low fat later switched to high fat and was retarded in rats on the low-fat diet. We feel that these data, as well as previous reports from our laboratory, justify additional experiments on human subjects. PMID- 6922187 TI - Premature births. PMID- 6922186 TI - Postpartum depression. PMID- 6922189 TI - Hallelujah! Common sense at last!. Interview by Ethel Gillette. PMID- 6922188 TI - Pulmonary disease. PMID- 6922190 TI - Patient focus. PMID- 6922191 TI - [Kallikrein]. PMID- 6922192 TI - [Changes and observation of instructions for breast feeding given at our clinic]. PMID- 6922193 TI - [Current status of breast feeding. The concept of the Clinic for Mothers and Infants and the service activities]. PMID- 6922194 TI - [An attempt at encouragement of breast feeding: prediction of vitamin K deficiency in newborn infants and its management]. PMID- 6922195 TI - [Observation on initiation of breast feeding: the relationship between Okeya's method of breast massage and the quantity of milk secretion]. PMID- 6922196 TI - [Evaluation of various factors related to breast feeding]. PMID- 6922197 TI - [Hemorrhage due to vitamin K deficiency in infants and breast feeding]. PMID- 6922198 TI - [Significance of inclusion of classical work activities in the health care of pregnant women]. PMID- 6922199 TI - [Care of an infant with extremely low birth weight who successfully underwent surgery of patent ductus arteriosus]. PMID- 6922200 TI - [Midwife's role in the reduction of perinatal mortality]. PMID- 6922202 TI - [Ontogeny and psychosocial development of men]. PMID- 6922201 TI - [The past and present of customs related to childbirth. 7. Ceremonial bathing of the infant]. PMID- 6922204 TI - [Medical scope. Mechanism of labor induction (2)]. PMID- 6922205 TI - [Acute diseases of children in primary care - clinical conditions in the diseases and training of the family members]. PMID- 6922206 TI - [Description of various types of acute diseases of children and their management]. PMID- 6922203 TI - [Intensive nursing during delivery at a midwifery clinic]. PMID- 6922207 TI - [Injuries in children]. PMID- 6922208 TI - [Development of acute diseases in children in hospitals and practice of their nursing]. PMID- 6922209 TI - [Support of the family with a child in a serious condition]. PMID- 6922210 TI - [Support of mothers of children with acute clinical conditions]. PMID- 6922212 TI - [Nursing of a child with convulsive attacks - with special reference to the care of an infant with acute apneic attacks]. PMID- 6922211 TI - [Nursing of children with acute conditions - cases of encephalitis following rubella, Kawasaki disease, and suppurative meningitis]. PMID- 6922213 TI - [Nursing of a child with status asthmaticus - an acute case requiring mechanical ventilation]. PMID- 6922214 TI - [Nursing management of children with burns]. PMID- 6922215 TI - [In search of systematic nursing - reflection and evaluation of assistance extended to a child with septicemia and to his mother]. PMID- 6922216 TI - [Innovation in water intake for prevention of major attacks and nursing of children with asthma]. PMID- 6922217 TI - [Intra-operative nursing and evaluation of its recording format]. PMID- 6922218 TI - [Nursing diagnosis: the head region. Diagnostic indicators and its significance]. PMID- 6922220 TI - [Rehabilitation nursing in activities of daily living of patients with acute myocardial infarction - changes in the pressure-rate product during meal-time and excretion]. PMID- 6922219 TI - [Nursing diagnosis: the head region. Detection of abnormalities of the cranial nerves and nursing diagnosis - the relationship to nursing planning]. PMID- 6922221 TI - [Support of ambulatory diabetic patients - a survey on trust, compliance, and dissatisfaction with the diet therapy and patients' current emotional states]. PMID- 6922223 TI - [Clinical description and nursing of SLE (systemic lupus erythematosus). Steroid therapy and related problems]. PMID- 6922224 TI - [The concept and clinical description of SLE (systemic lupus erythematosus)]. PMID- 6922222 TI - [Planned periods of rest in the intensive care unit: nursing care activities and intracranial pressure]. PMID- 6922225 TI - [Clinical description and nursing of SLE (systemic lupus erythematosus). Immunosuppressive therapy of SLE]. PMID- 6922226 TI - [Clinical description and nursing of SLE (systemic lupus erythematosus). Prognosis in SLE]. PMID- 6922227 TI - [Clinical description and nursing of SLE (systemic lupus erythematosus). Nursing of a patient with repeated hospitalization]. PMID- 6922229 TI - [Clinical description and nursing of SLE (systemic lupus erythematosus). On anxiety of SLE patients being cared for at home - results of a survey]. PMID- 6922228 TI - [Clinical description and nursing of SLE (systemic lupus erythematosus). Nursing of a patient during steroid therapy]. PMID- 6922231 TI - [Nursing of SLE patients undergoing plasma exchange]. PMID- 6922230 TI - [Nursing of an SLE patient with disturbances of the central nervous system - rehabilitation of a patient with aphasia, apraxia, and agnosia]. PMID- 6922232 TI - [Pregnancy and delivery in SLE]. PMID- 6922233 TI - [Review of nursing of an SLE patient with numerous complaints - reasons for frequent nurse calls. A case conference]. PMID- 6922234 TI - [Nursing of patients undergoing endoscopic embolization of esophageal varices]. PMID- 6922236 TI - [Nursing diagnosis: nursing diagnosis of otorhinolaryngological diseases]. PMID- 6922235 TI - [Nursing care in acute exacerbation of cor pulmonale - a case study]. PMID- 6922237 TI - [Contamination of combined infusion solutions - its occurrence and prevention]. PMID- 6922238 TI - [Medical electronics for nurses. (1). Devices used in medical electronics - problems and their solutions]. PMID- 6922239 TI - [Rehabilitation nursing in activities of daily living of patients with acute myocardial infarction. (3). Changes of PRP (pressure-rate products) during shampooing and ambulation and their application to nursing]. PMID- 6922240 TI - [Planned periods of rest in the intensive care unit: nursing care activities and intracranial pressure]. PMID- 6922241 TI - [Nursing training to nurture a proper attitude to research]. PMID- 6922242 TI - [On the hospice movement (2)]. PMID- 6922243 TI - [Re-evaluation of nursing education: in an example in training at a public health clinic at the School of Nursing, Keio Gijuku University School of Medicine]. PMID- 6922244 TI - [The image of nurses]. PMID- 6922246 TI - [In search of educational humanity (7). The theory of teaching. 2]. PMID- 6922245 TI - [Nursing education: establishment of a school of nursing in a university]. PMID- 6922247 TI - [Reflection on the seminars for training of nursing instructors in the past 5 years in the Okayama Prefecture]. PMID- 6922248 TI - [Hospice movement in a world which has come to a reflective stage. A study of the background of the modern hospice. (1)]. PMID- 6922249 TI - [The concept of the patient's death in nursing education]. PMID- 6922250 TI - [Developmental changes of nursing students in their attitudes to study and to the nursing profession]. PMID- 6922251 TI - [Search of educational humanity. (8) Teaching theories. 3]. PMID- 6922252 TI - [The Constitutions and daily lives]. PMID- 6922253 TI - [Trends in public health nursing and future problems]. PMID- 6922254 TI - [The legislative bills for protection and maternal and child health]. PMID- 6922255 TI - [Problems of the aged and public health nursing activities]. PMID- 6922256 TI - [Adult welfare and lives of local residents]. PMID- 6922257 TI - [Problems of public health centers and clinics]. PMID- 6922258 TI - [Public relations activities of public health clinics]. PMID- 6922259 TI - [Structures of public health budgets and budget presentation]. PMID- 6922260 TI - [Problems in industrial health and public health nursing activities]. PMID- 6922261 TI - [Re-evaluation of children's health]. PMID- 6922263 TI - [Lives of public health and school nurses]. PMID- 6922262 TI - [Symposium. Public health nursing activities in maternal and child health in Kyoto]. PMID- 6922264 TI - [Public appeal enhancement in organizational activities: implementation of public policies and their incorporation into citizens' organizations]. PMID- 6922265 TI - [Unification of nursing and public health nursing education--on the theory of public health nursing. I]. PMID- 6922267 TI - [In search of patients suffering from the ill effects of manganese mining]. PMID- 6922266 TI - [NHS in Scotland and Denmark. (10). Home nurses and day care centers in Denmark]. PMID- 6922268 TI - [Follow-up of junior high school children with hypertension into young adulthood]. PMID- 6922269 TI - [Self care exercised by self-employed pregnant and puerperal women]. PMID- 6922272 TI - An education program which prepares nurses to teach breast self-examination. AB - The importance of competent and regular breast self-examination in the early detection and improved outcome of breast cancer cannot be emphasized enough. In their contacts with women, nurses are in an opportune position to promote BSE through education and demonstration. Breast self-examination is an area where many nurses are not comfortable. However, with planned and organized instruction, professional nurses can assume the role of teaching this important skill. Breast self-examination can then be incorporated into any clinical setting where professional nursing is practiced. PMID- 6922270 TI - The effect of sibling visitation on bacterial colonization rate in neonates. AB - The effect of postpartum sibling visitation on the incidence of bacterial colonization in neonates was investigated in a 32-bed obstetrical unit of a midwestern university hospital. Siblings, following a temperature check, handwashing with a Hibiclens solution, and the donning of a patient covergown, were allowed unrestricted interaction with the infant. Statistical analysis of discharge cultures of nares and umbilici revealed that there was no significant difference between the control group and the experimental group. There was no difference between the two groups in the chart audit for postnatal infection at the first pediatric visit. Data analysis supported the hypothesis that sibling visitation does not increase bacterial colonization in neonates. PMID- 6922271 TI - Postmenopausal osteoporosis. AB - It is the responsibility of nurses to be informed about osteoporosis, especially about measures which may protect against rapid and early bone loss, and to share this knowledge with patients. The role of the nurse is to educate: to present known data about diet, exercise, and calcium and vitamin D supplementation. It is also appropriate to share knowledge relating to both the benefits and risks of estrogen replacement therapy. Only by being well informed will a woman be able to decide intelligently what therapy would best protect her from osteoporosis. The role of the nurse in not to advise women on what measure to choose but to give information and encouragement so women will feel confident enough to make an informed choice. PMID- 6922273 TI - Evaluating the effectiveness of a perinatal outreach education program. PMID- 6922274 TI - An early postpartum hospital discharge program: implementation and evaluation. AB - The philosophy of the FBC strengthens the concept of childbirth as a normal physiologic process. Couples are guaranteed a high level of quality nursing and medical care. Simultaneously, provisions are made to enhance the family's assertiveness in obtaining a satisfying experience in the hospital that extends to the home environment. With careful planning and decision making throughout the pregnancy, early discharge becomes a satisfying and safe alternative for families and provides a means to decrease the ever rising cost of health care. PMID- 6922275 TI - Postpartum home visits by maternity nursing students. AB - Fewer babies are being born; hospital postpartum days are being shortened; and many families are choosing home births: These facts have prompted nursing educators to seek maternity experiences for students outside the hospital setting. At the university where the student-visit program was implemented, faculty appreciated the need for follow-up home care and focused on more than the experiences in prenatal clinics and the acute-care setting. Rather than turning the family over to another community service or colleague when indicated, second and third home visits are being considered. These additional visits would assure a greater opportunity for primary prevention in the care of the total family. Hospital management and home-care maternity nurses have found that postpartum visits have decreased the need for parents to return to the emergency room or the hospital. Problems have been anticipated or assessed and nursing intervention provided on the home visit. This service gradually is becoming available to more families, with both physical and psychosocial needs being considered. It is hoped that it soon will be provided to all families. Postpartum families, nurses, and nursing students benefit from follow-up postpartum visits in the home. The families are assisted in their parenting roles and nurses gain satisfaction in providing continuity of care. PMID- 6922277 TI - Relationship of early bonding to initial infant feeding patterns in bottle-fed newborns. PMID- 6922276 TI - Effects of an educational gynecological exam on women's attitudes. PMID- 6922278 TI - Fetal monitoring. PMID- 6922279 TI - Breastfeeding risks. PMID- 6922280 TI - Prepared-childbirth research. PMID- 6922281 TI - Semantics of bonding. PMID- 6922282 TI - [The proceedings of the 35th anniversary celebration and annual convention of the Japanese nursing association]. PMID- 6922283 TI - [Medical topics: alcohol consumption and breast cancer]. PMID- 6922284 TI - [Medical topics: prolactinoma]. PMID- 6922285 TI - [To Japanese friends who welcomed and opened their minds to us: expectations on the future of the Japanese Nursing Association]. PMID- 6922286 TI - [Statistical file: programs for training of nursing instructors]. PMID- 6922287 TI - [Burnout syndrome and nursing: a socio-psychological analysis]. PMID- 6922289 TI - [Report on the section of midwifery of the annual convention of the Japanese Nursing Association]. PMID- 6922290 TI - [Report on the section of nursing of the annual convention of Japanese Nursing Association]. PMID- 6922288 TI - [Report on the section of public health nursing of the annual convention of Japanese Nursing Association]. PMID- 6922291 TI - [Regional welfare of the aged and the role of public health nursing]. PMID- 6922292 TI - [Childbirth in the 21st century - the importance of midwifery]. PMID- 6922293 TI - [Nursing and public policies]. PMID- 6922296 TI - [Let us recognize the role of the nursing profession: presidential address]. PMID- 6922295 TI - [Interview with Dr. Ohlson: on upgrading nursing schools to a 4-year university level]. PMID- 6922294 TI - [Caring for my mother]. PMID- 6922297 TI - [Activities of nurse practitioners in other countries; U.S.A., Philippines and Japan]. PMID- 6922298 TI - [Case report of a CHP]. PMID- 6922299 TI - [Voice of the community inhabitants]. PMID- 6922300 TI - [Establishing the primary health post]. PMID- 6922301 TI - [A study of risk approach for high-risk maternity care]. PMID- 6922302 TI - [Care of the high-risk newborn infant]. PMID- 6922304 TI - [Survey on the teaching-learning of fundamentals of nursing - program for baccalaureate students]. PMID- 6922303 TI - [Research design for experimental studies]. PMID- 6922305 TI - [Study of Roy's adaptation model]. PMID- 6922306 TI - [A study on nursing education reflecting student nurses' concerns]. PMID- 6922307 TI - [Primary health care services in medically underserved areas: since the start of operation 1 year ago]. PMID- 6922308 TI - [Problems related to the implementation of the CHP system]. PMID- 6922309 TI - ASHA constituents--a status report. PMID- 6922311 TI - Patterns of change in adolescent smoking behavior and results of a one year follow-up of a smoking prevention program. AB - A smoking prevention program for adolescents conducted in two public middle schools focused on resisting peer pressure to smoke and understanding the intent of commercial cigarette advertising. One class in each school participated in the program group and one served as a control group. The program consisted of eight sessions and was conducted by first-year medical students. Data on smoking behavior and related information were obtained from self-administered questionnaires at baseline, at the conclusion of the program, and one year later. One year after the program was concluded, the proportion of non-smokers was higher among those who had participated in the program than among the controls. This suggests that routine implementation of smoking prevention programs in conventional school settings may be productive in reducing the prevalence of cigarette smoking. PMID- 6922310 TI - Predicting adolescent smoking. AB - Two hundred and ninety-seven seventh grade students (143 males and 154 females) participated in a prospective study to predict adolescent cigarette smoking behavior one year later. Predictor variables included 10 survey items assessing the smoking behavior of students' friends and family, students' school behavior and beliefs about smoking and students' intentions to smoke in the future. The one-year follow-up survey was administered under "bogus pipeline" conditions to enhance the validity of self-reported smoking status by including the collection of saliva thiocyanate samples. Univariate analyses indicated that smokers differed from nonsmokers on a number of measures and that there were few sex differences on either the survey variables or on smoking status. Stepwise discriminant function analyses revealed that it was possible to accurately predict the onset of adolescent cigarette smoking by combining the survey variables. The three variables that consistently accounted for the greatest proportion of te variance were number of friends who smoke, intentions to smoke in the future and percent of older siblings who smoke. The implications of this work for programs intended to prevent adolescent smoking are discussed. PMID- 6922312 TI - Update: mitral valve prolapse syndrome. AB - A contemporary "in" diagnosis in the field of cardiology is the mitral valve prolapse syndrome. This abnormality is evident in populations ranging from very young children to older adults. It is being recognized with increasing frequency among college and university students. In many cases, the syndrome is of limited consequence, while in others, it may be life threatening. This paper (1) defines what it is, (2) reports on its occurrence, (3) depicts some relationships with related health entities and (4) discusses certain implications for health professionals and heart health education. PMID- 6922313 TI - State responsibility for the control of asbestos in the schools. PMID- 6922314 TI - Incest: the school's role. AB - Most would agree that sexual abuse/incest is harmful to the family structure as well as individual family members. Numerous people have been traumatized, some irreparably, due to their involvement in an incestuous relationship. The school must become a leader in and advocate for a reduction in the incidence of sexual abuse/incest. The school presently has mechanisms for the detection, intervention and prevention of incestuous behavior. School personnel must assume their legal and, perhaps more importantly, moral responsibility to protect and promote the health and welfare of children. School personnel must be aware of the existence of incest, be cognizant of indicators, be observant for its detection, decide to become involved, report and follow-up on the report and be a support group for community agencies and the family. School personnel can make the difference. As it has been said, "If schools are not or will not be part of the solution, could they be part of the problem?" PMID- 6922315 TI - Adolescent perceptions of family health behavior: a tenth grade educational activity to increase family awareness of a community cardiovascular risk reduction program. PMID- 6922316 TI - The evaluation of a Cardiovascular School Health Curriculum: an assessment of long-term cognitive retention and attitudinal correlates. AB - This study provided evidence that the Cardiovascular School Health Curriculum was successful in increasing the knowledge levels of high school students and maintaining significant portions of that knowledge during a six month period, indicating that with a strong, well developed curriculum, relatively permanent change in knowledge levels can be achieved. This was particularly gratifying to the researchers who believe that the appropriate knowledge of the cardiovascular system, heart diseases and methods of preventing heart and circulatory problems are essential foundations for having positive impact of youths' future behavioral choices. Additional longitudinal studies are planned to augment the findings of this study. PMID- 6922317 TI - Comparison of school-based treatments for adolescent obesity. PMID- 6922318 TI - Questions about MVP remain unanswered. PMID- 6922319 TI - [Importance of classroom training]. PMID- 6922320 TI - [Teaching and learning methods and educational media in nursing training at school]. PMID- 6922321 TI - [Curriculum preparation and the weight of classroom training]. PMID- 6922322 TI - [Class seminar using a clinical record for practical training]. PMID- 6922323 TI - [Classroom training in medication - with special reference to training in subcutaneous injections]. PMID- 6922324 TI - [Psychodrama in the study of nursing relationship]. PMID- 6922325 TI - [Focal point in observation of patients' families and nursing intervention at clinical scenes]. PMID- 6922326 TI - [The dynamics and management of burnout]. PMID- 6922327 TI - [Philosophical and psychological approaches to the mind and body]. PMID- 6922328 TI - [Personnel management and scheduling of nursing duties]. PMID- 6922330 TI - [Basic education in nursing]. PMID- 6922329 TI - [Research on nursing administration at Toranomon Hospital. 6. Implementation of a patient classification system. II]. PMID- 6922331 TI - [Pre-and postoperative nursing of a patient with mitral valve stenosis - with special reference to practical instructions (1)]. PMID- 6922333 TI - [Community mental health care in Hawaii. Interview by M. Kawano]. PMID- 6922332 TI - [A new trend in education of allied health sciences: competency-based education. (1)]. PMID- 6922335 TI - [Understanding the religious needs of the patient]. PMID- 6922334 TI - [Death and the role of religion in medical care. Discussion]. PMID- 6922336 TI - [Religion of the patient and medical ethics]. PMID- 6922337 TI - [Nursing and religion - on spiritual care]. PMID- 6922338 TI - [Focal point in nurses' observation of patients' families and nursing intervention in clinical settings (2)]. PMID- 6922339 TI - [Philosophical and psychological approaches to the mind and body. (2)]. PMID- 6922341 TI - [Better patient care through nursing research (1)]. PMID- 6922342 TI - [Physical and personnel requirements in clinical training - problems in nursing administration]. PMID- 6922343 TI - [A new trend in allied health science education: competency-based education, (2)]. PMID- 6922345 TI - [An interview with Dr. Virginia M. Ohlson. Trends in American nursing - with special reference to the unification model. Interview by A. Maeda, S. Nagano, K. Shimizu]. PMID- 6922346 TI - [Nursing in support of the goal of health for all by the year 2000]. PMID- 6922340 TI - [Personnel evaluation and promotion standards]. PMID- 6922347 TI - [Nursing process: nursing of patients with cognition disorders. Physiopathology of cognition disorders]. PMID- 6922348 TI - [Nursing process: nursing of patients with cognition disorders. Diagnosis and treatment of cognition disorders]. PMID- 6922344 TI - [A trial in clinical training in adult nursing (1). Improvement in the training and practice in 6 areas of nursing]. PMID- 6922349 TI - [Nursing process: nursing of patients with cognition disorders. Nursing of patients with cognition disorders in the chronic stage]. PMID- 6922351 TI - [Nursing process: nursing of patients with cognition disorders. Discussion: evaluation of the nursing process]. PMID- 6922352 TI - [Bedside examination: keypoints in nursing and interpretation of data. Respiratory function tests]. PMID- 6922350 TI - [Nursing process: nursing of patients with cognition disorders. A case study- teaching using the record of a patient with Shy-Drager syndrome who was assigned to a team of student nurses]. PMID- 6922353 TI - [Interactions with a patient with stomach cancer who suddenly became unable to drink fluid--unexpected disclosure of a personal secret by the patient]. PMID- 6922355 TI - [In search of humane nursing. Assistance of an aged, bedridden patient]. PMID- 6922356 TI - [In search of a new nursing philosophy. XXII. The meaning of illness]. PMID- 6922354 TI - [Nursing of patients suffering from adverse effects of radiotherapy--a survey of their diet]. PMID- 6922357 TI - [Mental disorders in myocardial infarct]. PMID- 6922358 TI - [Nervous system lesion in lymphogranulomatosis]. PMID- 6922359 TI - [Sexual disorders]. PMID- 6922361 TI - [Thermographic study method in medical practice]. PMID- 6922360 TI - [First aid in poisoning from marine molluscs]. PMID- 6922362 TI - [Psychotherapy in acupuncture]. PMID- 6922363 TI - ["Minor" psychotherapy at a sanatorium-preventorium]. PMID- 6922364 TI - [Funicular myelosis]. PMID- 6922365 TI - [Taking of patient specimens for laboratory studies]. PMID- 6922366 TI - [Work organization for the senior nurse]. PMID- 6922367 TI - [Efficient utilization of the work time of nurses]. PMID- 6922368 TI - [Work of a centralized sterilization unit]. PMID- 6922370 TI - [Arterial pressure measuring technic]. PMID- 6922369 TI - [Participation of polyclinic nurses in organizing the expertise of work disability]. PMID- 6922371 TI - [Scientific organization of work introduced into the practical work of paramedical personnel]. PMID- 6922372 TI - [Work of a district nurses' council in introducing the elements of the scientific organization of work]. PMID- 6922373 TI - [Side effects of drug preparations intended for use with the elderly]. PMID- 6922374 TI - [Health education work in a department]. PMID- 6922375 TI - [Work of a hospital nurses' council]. PMID- 6922376 TI - ["Young Medical Student" Club]. PMID- 6922378 TI - [Deontology in the work of the nurse]. PMID- 6922377 TI - [Emergency care in spontaneous pneumothorax]. PMID- 6922380 TI - [Health protection for children in the USSR]. PMID- 6922381 TI - [Achievements of Soviet traumatology]. PMID- 6922379 TI - [Acute pancreatitis]. PMID- 6922383 TI - [Medical activity: an important aspect of the mode of life]. PMID- 6922382 TI - [Current problems of oncology]. PMID- 6922384 TI - [Scientific organization of the work of paramedical and junior personnel]. PMID- 6922385 TI - [Organization of the work of the head nurse]. PMID- 6922386 TI - [Scientific organization of the work in the nurse's duty in a dental surgery office]. PMID- 6922388 TI - [Role of the journal Meditsinskaia sestra in raising the quality and standard of medical care]. PMID- 6922387 TI - [Journal Meditsinskaia sestra is a constant friend and aide]. PMID- 6922389 TI - [Role of nurses' conferences in raising the qualifications of nurses]. PMID- 6922391 TI - Myosin active-site trapping with vanadate ion. PMID- 6922390 TI - [Evaluation of the combined use of Nico-padutin forte and depot-Padutin in peripheral arterial occlusive disease]. PMID- 6922394 TI - When your patients ask about incontinence. PMID- 6922393 TI - A review of dementia. PMID- 6922392 TI - Family change and health policy. PMID- 6922395 TI - Facets of obstetrics in domestic animals. PMID- 6922396 TI - Infant feeding. PMID- 6922397 TI - A dying species? Survival and revival are up to us! PMID- 6922398 TI - Case study: symphysiotomy and vesico-vaginal fistula. PMID- 6922399 TI - A few funny cells. PMID- 6922400 TI - Bacteriophages for methicillin resistant Staphylococcus aureas (MRSA) PMID- 6922402 TI - Planning operating departments No. 4. Operational policies. PMID- 6922403 TI - Operating room nurses--who needs them? PMID- 6922401 TI - On trial: nursing. PMID- 6922404 TI - The cleaning and disinfection of flexible endoscopes and their accessories. PMID- 6922405 TI - Short course on the principles of operating department nursing. PMID- 6922408 TI - Certification for specialty nursing practice. PMID- 6922407 TI - Nursing care of patients with syndrome of inappropriate antidiuretic hormone secretion. PMID- 6922406 TI - The year of the professional: reflections on 1981-82. PMID- 6922409 TI - Nosocomial infections: risks and preventive measures for I.V. nurses. PMID- 6922410 TI - Analysis, application and evaluation of the NITA standards of practice. PMID- 6922411 TI - Possible occupational hazards associated with the preparation/administration of antineoplastic agents. PMID- 6922412 TI - Abstract papers submitted by abstract presenters at NITA's tenth annual meeting. PMID- 6922414 TI - Supplementation of I.lV. teams with licensed practical nurses. PMID- 6922413 TI - Relationship between pH of intravenous medications and phlebitis: an experimental study. PMID- 6922415 TI - Intermittant I.V. antibiotic therapy at home. PMID- 6922417 TI - Sharing: Home Rx--wet nose, soft fur, and wagging tail. PMID- 6922416 TI - Behavioral management in I.V. therapy. PMID- 6922418 TI - Think fast: what do your know about cardiac drugs for a code? Continuing education credits. PMID- 6922419 TI - Saving your elderly patient's skin. PMID- 6922420 TI - How to make a lonely place a little less lonely. PMID- 6922421 TI - Helping patients through the recurring nightmare of herpes. PMID- 6922422 TI - Rose demanded a special kind of love. PMID- 6922423 TI - Play it safe: don't use these abbreviations. PMID- 6922424 TI - Emergency! First aid for wounds. PMID- 6922425 TI - Deciphering diagnostic studies: oculoplethysmography. PMID- 6922426 TI - How to do it better. PMID- 6922428 TI - What do the courts expect from nurses? PMID- 6922427 TI - Got problems that won't go away?... Solve them creatively! PMID- 6922429 TI - When nurses are accused of murder: the melodramatic effects of media coverage. PMID- 6922430 TI - Delegating safely within the law. PMID- 6922431 TI - If you're over 21, start thinking retirement, how will you support yourself when you retire? Most nurses don't know. If you're one of them, read on. PMID- 6922432 TI - Your attitudes toward the elderly--and how they affect your nursing care. PMID- 6922434 TI - Court case: what makes a witness "expert"? PMID- 6922433 TI - Tips for teaching older adults. PMID- 6922435 TI - Staff development: two different philosophies? PMID- 6922437 TI - Patient care planning strategies. PMID- 6922436 TI - Assessment: a nursing model. PMID- 6922439 TI - Risk management: a hospital-wide approach. PMID- 6922438 TI - Refusing to participate in abortions. Law for the nurse manager. PMID- 6922440 TI - A common-sense approach to primary nursing. PMID- 6922441 TI - The journal club: one method of developing head nurses. PMID- 6922442 TI - The art and science of management: staying in focus. PMID- 6922443 TI - Opportunity for managerial growth. PMID- 6922444 TI - Work evaluations: are they effective? PMID- 6922446 TI - Bickering over baccalaureates, again? PMID- 6922445 TI - Focus: on the NLN's statement on nursing roles--scope and preparation. PMID- 6922448 TI - Studying the costs of nursing education programs. PMID- 6922447 TI - Effect of elastase on the elastic tissues in the thoracic aorta. PMID- 6922449 TI - National Orthopedic Hospital to be converted into an Accident Center (NOH) and Rehabilitation Medicine Center (NOH) to be constructed in 20 ha government lot. PMID- 6922450 TI - The Philippine Population Program. PMID- 6922451 TI - Ten commandments for parents. PMID- 6922452 TI - Third National Conference on Cancer Nursing. PMID- 6922453 TI - The role of the educator in nursing in regards to the development of the nursing service. PMID- 6922454 TI - Learning needs of cancer patients: a comparison of nurse and patient perceptions. AB - The purposes of this study were to discover and compare patients' and nurses' perceptions of the learning needs of cancer patients. Using rating scales, 33 nurses and 27 patients rated the degree of importance of learning 36 informational items, including nutrition, treatment, and diagnostic testing. In addition, nurses and patients ranked six content areas according to: how problematic each area was for the patient; how much knowledge the patient had about each area; and how much the patient wanted information about each area. Results indicated that significant differences existed between nurses' and patients' perceptions of the learning needs of cancer patients. Nurses rated the degree of importance of the 20 general information items significantly higher than did the patients. The rank order of the six content areas for each of three questions by nurses and patients showed nurses ranked dealing with feelings as the most problematic area for patients, while patients ranked this area low. PMID- 6922455 TI - Sensory information, behavioral instructions and coping with sensory alteration surgery. AB - This study compared the effect of a behavioral type of personal control and cognitive personal control information on cataract patients' postoperative orientation, indeterminate stimulus experiences, mood states, and performance (Ellis, 1972; Johnson, 1975; Seligman, 1975). Subjects were 40 patients, age 50 or older, scheduled for their first unilateral cataract surgical experience. Using a four-condition experimental design, patients were randomly assigned to: (1) behavioral instructions (behavioral control), (2) sensory information (cognitive control), (3) both behavioral instructions and sensory information, or (4) general information. It was found that neither behavioral nor cognitive control interventions had a significant effect on any of the dependent variables. However, the combination of behavioral and cognitive control intervention significantly reduced the number of days after discharge before patients elected to venture from their homes. No significant differences were found between experimental conditions in frequency of patient-reported indeterminate stimulus experiences (ISE). PMID- 6922456 TI - A comparison of the anxiety-reducing potential of two techniques of bathing. AB - This study compared the effects of the towel bath and the conventional bed bath on patient anxiety. The sample of 105 patients were divided into two groups- those who would be having invasive procedures and those with unrelieved pain. Anxiety was measured using the State-Trait Anxiety Inventory (STAI), the Palmar Sweat Index (PSI), and the Behavioral Cues Index (BCI). The scores from the STAI A-State subscale supported the hypothesis that the towel bath resulted in a significant decrease in anxiety for the sample as a whole and for the invasive procedure subsample. The hypothesis was rejected for the unrelieved pain subsample. Scores from the Palmar Sweat Index and the Behavioral Cues Index did not support any of the hypotheses. Based on the findings of this study, bathing is recommended for its anxiety-reducing effects. PMID- 6922457 TI - Reducing post-catheterization bladder dysfunction by reconditioning. AB - The purpose of this study was to determine the effect of reconditioning upon bladder dysfunction caused by prolonged catheterization. Eight women undergoing surgery with baseline residual urine volumes (RUVs) not greater than 25 ml and catheterization durations of 36 to 106 hours qualified as subjects. Immediately prior to catheter removal, the four treatment group subjects received reconditioning, a procedure in which their catheters were clamped for three hours followed by five minutes of urinary drainage. This cycle was repeated twice more, totaling nine hours, ten minutes. The four control group subjects received no reconditioning. After catheter removal, reconditioned subjects resumed natural micturition significantly sooner than non-reconditioned subjects (t = -2.82, df = 6, p less than 0.05). A t test showed no significant differences between the groups in post-indwelling catheterization RUVs following the first micturition, probably due to the small number of subjects, since the control group's mean post catheterization RUV increased to a physiologically abnormal level (42.25 ml), while the reconditioned group's mean RUV stayed within normal limits. This study should be repeated to test for statistical significance in larger samples. PMID- 6922458 TI - Compliance: an interactionist approach. AB - Compliance is central to health care, but by its very nature it remains problematic to health care providers and health care receivers. In this article an interactional approach, the utilization of role theory, in the study of compliance is proposed. Rationale for the need for such a framework is provided through the presentation and critique of currently used models and theories, such as the medical model, the health belief model, control theory, and learning theory. Assumptions of the proposed framework are presented, and four components are identified when considering compliance enactment from an interactional perspective. These are: self-concept, role enactment, complementary roles, and periodic evaluation of role enactment by self and others. Several theoretical propositions evolve as central to the development of a unified framework for compliance. The propositions can be considered potential hypotheses. This article demonstrates one approach to theory development in nursing. PMID- 6922459 TI - A study of construct validity: simultaneous as a measure of nurse practitioners' problem-solving skills. AB - A national sample of 46 nurse practitioners (NPs) and a Midwestern sample of 31 nurses completed five instruments designed to provide evidence of the construct validity of patient management problems (PMPs). The subjects completed three simulations, a multiple-choice cognitive examination in the content are of the simulations, and a demographic questionnaire. The first hypothesis stated that a claim for the construct validity of simulations would be warranted if significant differences were found between performance of NPs and nurses on simulations designed for NPs. A second hypothesis stated that no significant differences would be found across the three different simulations. The cognitive examination was hypothesized to be a meaningful covariate, as performance on a simulation depends in part on knowledge of the content area of the simulations. The examination was not found to be a significant covariate in this analysis. Meaningful differences were found between NPs and nurses, supporting the claim for the construct validity of the simulations. Meaningful differences were also found across the three simulations for both groups of subjects, suggesting that the second hypothesis of consistency of performance may have been inappropriately formulated. One measurement characteristic of the simulations may be difficulty level. PMID- 6922463 TI - The measurement of change in nursing research: statistical considerations. PMID- 6922461 TI - Determinants of staff nurses' perceptions of autonomy within different clinical contexts. AB - Studies of nurses and other health professionals indicate that autonomy is an important determinant of job satisfaction and turnover. This study analyzed selected characteristics of hospital nursing units to identify those features of the work setting that influence staff nurses' perceptions of autonomy: comparisons among nurses who work in different clinical areas were made. Data were collected by interviewing 789 nonsupervisory registered nurses who were employed full time at one large university-affiliated hospital. Personal and job related information was obtained for each nurse. Structural features of units, such as workload, were gathered from head nurse reports and hospital records. Findings indicated that nurses' perceptions of autonomy are influenced by both personal characteristics of the nurse and structural features of the units. The nurse's sense of personal efficacy and the relationship she has with her head nurse are two important determinants of autonomy across all units. Workload, primary nursing, and staffing patterns are influential factors in predicting autonomy for nurses who work in critical care areas. Implications of these findings for nursing administrators are discussed. PMID- 6922460 TI - Informed consent of special subjects. PMID- 6922462 TI - Resources for graduate education: a report of a survey of forty states in the Midwest, West, and Southern regions. AB - This article data on the need for doctorally prepared nurses and the resources for their preparation in 40 states in the Midwest, West, and South. A mailed questionnaire was used to collect data from the administrative heads of 58 graduate nursing education programs. Results reported in this article are on: nursing faculty responsibilities, projected faculty needs, research supports for faculty, sabbatical leaves granted nursing faculty, research and interdisciplinary activities of nurse faculty, numbers of nurse and non-nurse doctorally prepared faculty, reported criteria for and difficulties in recruiting doctoral nurse faculty, initiating change in graduate nursing education and the reasons for change, the research requirements in master's nursing programs, and the reasons cited for establishing doctoral nursing programs within the 40 states. Questions that educators face in the development of quality programs of doctoral nursing education are discussed. PMID- 6922464 TI - The effect of preoperative intervention on delirium in cardiac surgical patients. PMID- 6922465 TI - Sleep-awake patterns following cerebral concussion. AB - This study compared sleep-awake patterns in clients following head injury with their sleep-awake patterns prior to head injury. Data were collected from 75 subjects who had experienced a minor head injury (MHI) with a disturbance in consciousness three months prior to filling out a questionnaire. The majority of the clients were males, 16 to 30 years old, who had been involved in a motor vehicle accident which resulted in MHI. Questions related to the sleep-awake patterns before and after head injury. Sleep-awake patterns following head injury differed from sleep-awake patterns prior to head injury in the following sleep indicators: sleep interruptions per week and per night increased significantly (p less than .004, p less than .001) as did the time needed to function at peak efficiency upon awakening (p less than .001). The subjects reported significant increases (p less than .02) in the number of times per month in which they were unable to return to sleep after an early morning awakening coupled with the difficulty in returning to sleep (p less than .04). Overall, the clients reported significantly decreased sleep quality (p less than .02) and increased complaints about sleep following head injury (p less than .001). An increase in the time of consciousness disruption following head injury was related to the subjects having a tendency to sleep longer and to recall fewer, less vivid dreams. A decreased level of consciousness upon admission to the emergency department at time of injury correlated with the increased number of arousals during the sleep cycle and the reduced intensity of auditory stimulus needed to interrupt sleep. The anatomical site of the head injury and the duration of post-traumatic amnesia (PTA) were found to have no significant effect upon sleep-awake patterns following MHI. PMID- 6922466 TI - The effect of oxygen administration on oral temperature assessment. AB - No research data are available on the effects of oxygen on oral temperature. This study sought to determine if oxygen administration via aerosol mask, venti-mask, or nasal prongs altered oral temperature as assessed in the sublingual pockets of the mouth. The population included 40 healthy male and female volunteers. Oxygen was administered using a repeated measure design with the subjects serving as their own controls and the oxygen devices presented in a counterbalanced order. An electronic thermometer recorded the temperature at the end of each 15-minute treatment/control period. There was no significant difference between the pre- and post-treatment measurements of the aerosol mask, venti-mask, and nasal prongs. The conclusion was that oral temperature assessed in the presence of oxygen administration is no different than oral temperature assessed without oxygen administration. PMID- 6922468 TI - Temperature monitoring in the neonate: a comparison of axillary and rectal temperatures. AB - This study investigated the differences between temperature taking in neonates by the axillary method and by the rectal method. A sample of 46 normal full-term neonates had axillary and rectal temperatures monitored for ten minutes by each method with mercury in glass thermometers. There were significant differences found between axillary and rectal temperatures when compared minute for minute. Stabilized axillary and stabilized rectal temperatures were not tested for difference because axillary temperatures did not meet the criteria for stabilization. A significant positive correlation was found between axillary and rectal temperatures. Axillary temperature taking may be a practical method for neonatal temperature monitoring. PMID- 6922467 TI - Parent coping behaviors, parent functioning, and infant temperament characteristics. AB - This study focuses on the relationship between parent coping behaviors, parent functioning, and infant temperament characteristics. One hundred mothers and fathers of two-to three-month-old infants answered a 154-item self-administered questionnaire. The following three parent-coping behavior patterns emerged: (1) seeking social support and self-development; (2) maintaining family integrity; and (3) being religious, thankful, and content. Parents who were depressed, anxious, and had somatic complaints perceived social support and self-development as more helpful and were less focused on maintaining family integrity. Parents who perceived their infant as having a more smiling, laughing temperament, and as a child who cries less, used coping behaviors designed to maintain family integrity; they were more religious, thankful, and content. Parents who were depressed and parents who were anxious saw their infants as less soothable and more distressed when faced with limitations. PMID- 6922469 TI - Sexual functioning, health beliefs, and compliance with high blood pressure medications. AB - This study compared sexual functioning in 84 hypertensive subjects enrolled in an inner city hypertensive program with a matched group of 84 nonhypertensive subjects attending ambulatory care. Using the Sexual Functioning Questionnaire (SFQ), hypertensive subjects achieved lower levels of sexual functioning than nonhypertensive subjects (F = 21.60, df = 1/164, p less than .001). The 84 hypertensive subjects were categorized according to drug regimen (simple, moderate, and complex) and diastolic blood pressure measurement (DBP) (controlled and uncontrolled). Health beliefs of both sexes, relationship between type of drug regimen and sexual functioning, and association between self-report compliance and sexual functioning were examined. In the health belief survey, males reported a greater frequency of drug-induced sex problems than females (p less than .01), use of a complex drug regimen was associated with low level of sexual functioning (p les than .01), and type of self-report compliance was not related to level of sexual functioning. Hydrochlorothiazide, propranolol, and hydralazine were used by 80 percent, 43 percent, and 20 percent of clients. Self report compliance was significantly related to controlled DBP (p less than .001). PMID- 6922470 TI - Two approaches to the management of long-term psychiatric outpatients in the community. AB - In this study, it was predicted that over a two-year period chronically ill psychiatric outpatients treated in a nursing social support program would experience a lower rehospitalization rate; more days out of hospital; less treatment drop-out; a greater decrease in symptoms; fewer medication increases; a greater increase in socialization, occupation, and satisfaction with life situation; and show better care ratings than similar patients attending a medication clinic. Forty-seven medication-maintained patients were randomly assigned to treatment conditions. After two years of treatment, medication clinic patients had improved socialization and satisfaction with care ratings and lowered depression and agitation ratings. There were no group differences on other outcome criteria. PMID- 6922471 TI - Time as an index of expanding consciousness with age. AB - Subjective time is explored as a developmental phenomenon of man's expanding consciousness. Eighty-five subjects, 60 to 88 years of age (X = 71.5) were tested to ascertain the relationship between age, movement (preferred walking rate), and time (perceived duration of a 40-second interval). Findings were compared to previous data on two younger age groups. Neither the age-time nor the movement time relationship was confirmed in this sample. However, a trend toward increased subjective time with age was suggested when comparisons were made across a broader age group. Sex and hemispheric lateralization may have influenced results and need consideration in further study of this problem. PMID- 6922472 TI - Facilitators and inhibitors of the emergency nurse practitioner role. AB - Factors that facilitate or inhibit implementation of the Emergency Nurse Practitioner (ENP) role were studied. ENPs were surveyed by questionnaire. Sixty eight (64.7 percent) responded, providing data about motivating factors influencing the decision to seek ENP education and subsequent job acceptance; current employment status; role concept; performance and autonomy; and barriers to practice. Nearly all program graduates had practiced as ENPs, but only 43 percent were doing so at the time of survey. Of the rest, a third were nurse practitioners in a nonemergency room setting (NPs), and 22 percent were practicing in other nursing roles (NNPs). Respondents were motivated to enter an ENP program by greater role credibility, autonomy, job advancement, learning new skills, and dissatisfaction with their jobs. Similarly, ENPs accepted their jobs because of the opportunity to use their new skills, available medical backup, and the location of employment. NPs and NNPs reported leaving ENP practice because of resistance from other health care providers. ENPs experienced resistance in their practice, although they believed the role was accepted by consumers and health care colleagues. They tended to perform tasks they believed appropriate to the role and not to perform tasks inappropriate to the role. Most ENPs reported role autonomy and a collaborative or independent practice. While 42 percent reported no barrier to practice, the majority of ENPs reported greater than one barrier. Resistance and legal status were the most frequently reported barriers. The need for further onsite and nationwide research on the ENP is suggested. PMID- 6922474 TI - Role orientation and role strain of clinical nurse faculty in baccalaureate programs. PMID- 6922473 TI - New baccalaureate graduates' perceptions of organizational conflict. AB - This study explores the process of professional socialization in a sample of newly graduated baccalaureate nurses whose first experience as practicing professionals was in a hospital organizational system. Professional socialization was defined in terms of concept of identity reassessment as proposed by Strauss and in terms of the new graduates' descriptions of their own behavior during conflictual situations in the work setting. These descriptions were identified as conflict-reporting behavior and analyzed from two aspects: the source of the conflict and the level reached by the behavior of the respondent, as defined by a model for organizational conflict proposed by Pondy. Although changes in conflict reporting behavior with increasing experience in the hospital bureaucracy were noted, the study findings showed no significant relationships between this behavior and ideas about the nursing role and the value of organizational inducements. Some trends in conflict-reporting behavior were noted in relation to three other variables: the size of the unit on which the new graduate was working, the identity of the other persons in the conflict, and the new graduates' work experience in a hospital system while in school. PMID- 6922476 TI - Meta-analysis. PMID- 6922477 TI - Small sample size. PMID- 6922475 TI - Professional autonomy among senior nursing students in diploma, associate degree, and baccalaureate nursing programs. PMID- 6922478 TI - Wound care No. 12. Which dressing and why - 2. PMID- 6922479 TI - Changes in community care courses. 1. Practical placements in basic nurse training. PMID- 6922480 TI - Falklands special: it's so good to be home! PMID- 6922481 TI - American dream - and reality. PMID- 6922482 TI - Nursing at the crossroads. 1. The role of the nurse. PMID- 6922483 TI - Ramstedt's procedure for relief of pyloric stenosis. PMID- 6922485 TI - The medicalisation of dying - 2. PMID- 6922484 TI - Hydronephrosis. PMID- 6922487 TI - A different kind of day unit. PMID- 6922488 TI - Nurse Smith's notes. Understanding drug treatment. I. PMID- 6922489 TI - Changes in community care courses. 2. Nursing attitudes and behaviour (concluded). PMID- 6922486 TI - Balancing the books. 3. Managing the budget at unit level. PMID- 6922491 TI - Is there a place for the lay midwife. PMID- 6922490 TI - A world of difference. PMID- 6922493 TI - Dialogue 1. Leadership and change in nursing. PMID- 6922492 TI - Community care study: secondary pelvic cancer. PMID- 6922494 TI - Common infestations. PMID- 6922495 TI - The nursing process in a psychiatric hospital. PMID- 6922496 TI - Nursing at the crossroads. 2. The nursing process and the role of the registered nurse. PMID- 6922497 TI - Antenatal classes: time for a new approach. PMID- 6922499 TI - The Maternity Defence Fund. Litigation: a simple step forward. PMID- 6922498 TI - The Maternity Defence Fund: complaints confined to childbirth. PMID- 6922500 TI - Penicillin allergy. PMID- 6922501 TI - Nursing in the EEC: divided we stand. PMID- 6922502 TI - Nursing in the EEC: for the common good. PMID- 6922503 TI - The point of contact. PMID- 6922504 TI - Community forum 9: Health visiting. An extended talking service. PMID- 6922505 TI - Community forum 9: Health visiting. Cutting out the abuse. PMID- 6922507 TI - Pacemakers: revolutionary ideas. PMID- 6922506 TI - Burns: injured by heat. PMID- 6922508 TI - Communication and control. PMID- 6922510 TI - Management, 5. Reactions to change. PMID- 6922509 TI - Abdominal aortic aneurysm: the pulsating mass. PMID- 6922511 TI - Nursing care study: nobody would listen to me. PMID- 6922512 TI - Luck: poor Peggy. PMID- 6922513 TI - Insomnia: breaking the habit. PMID- 6922514 TI - Sick leave: and on the fourth day... PMID- 6922515 TI - Notifiable infectious diseases. 2. From the mild to the lethal. PMID- 6922516 TI - Careers: occupational health nursing. PMID- 6922518 TI - Primary syphilis. PMID- 6922519 TI - Leboyer versus conventional care. PMID- 6922517 TI - Sleepless night, peaceful night. PMID- 6922520 TI - Time and a word. PMID- 6922521 TI - Farewell tonsils. PMID- 6922523 TI - Management. 6. Organisation and design. PMID- 6922524 TI - Pain: suffer the little children. PMID- 6922525 TI - Nursiong care study. Multiple sclerosis: a slow decline. PMID- 6922522 TI - No control. PMID- 6922527 TI - The paranoid profession. PMID- 6922526 TI - Anytown anecdotes: different manners. PMID- 6922528 TI - Management. 1. A manager's task. PMID- 6922529 TI - Notifiable infectious diseases. 3. The danger still exists. PMID- 6922530 TI - One community that cares. PMID- 6922532 TI - Television nurses: programmed for success. PMID- 6922531 TI - A case of getting used to it. PMID- 6922533 TI - Fallot's tetralogy. PMID- 6922534 TI - Notifiable infectious diseases. 1. Always a menace. PMID- 6922536 TI - Education forum 6: communication. Whatsamattayou? PMID- 6922535 TI - Specifics and rigour. PMID- 6922537 TI - Education forum 6: Communication. A fundamental skill. PMID- 6922538 TI - Pacemakers: when the heat dies. PMID- 6922539 TI - Living with cancer. PMID- 6922540 TI - Nursing care study: life support through his crisis. PMID- 6922541 TI - Crying: tears of care. PMID- 6922543 TI - Issues in nursing. 9. Master of her trade. PMID- 6922544 TI - Management. 4. Effective change takes time and effort. PMID- 6922542 TI - Issues in nursing. 9. Don't rest on your laurels. PMID- 6922545 TI - Education of asthmatics: learning to live with asthma. PMID- 6922546 TI - Asthma treatment in Norway: an exercise in rehabilitation. PMID- 6922547 TI - Nursing care study: removing a dangerous filter. PMID- 6922548 TI - Anytown anecdotes: ignorance is not bliss. PMID- 6922549 TI - Careers: attitudes to mental health. PMID- 6922550 TI - Renal actions of orthovanadate in the dog. PMID- 6922552 TI - [Sick person]. PMID- 6922551 TI - [Nutrition and drugs]. PMID- 6922553 TI - [Specialization in management and administration]. PMID- 6922554 TI - [Supervisors' week]. PMID- 6922555 TI - ["We are maids of all work"...]. PMID- 6922556 TI - [Genealogy of the future. 3. Postgraduate advanced training]. PMID- 6922557 TI - [What kind of nurse do patients esteem?]. PMID- 6922558 TI - [Chronotherapy: general principles]. PMID- 6922559 TI - [Ovulation method in regulating conception]. PMID- 6922560 TI - [Course of action for the Center for the Advanced Training of Teachers and Paramedical Personnel]. PMID- 6922561 TI - Common problems of the ear, nose, and throat. PMID- 6922562 TI - How to (and how not to) manage the patient with a lump in the neck. AB - In the management of a patient with an isolated lump in the neck, knowing what actions should not be taken is as crucial as knowing what should be done. A careful history and physical examination as well as guidelines such as the low prevalence of malignant lesions in children but the high prevalence in adults can aid the primary physician in reaching an accurate diagnosis. An extensive radiographic work-up, and possible peroral panendoscopy, may be required when malignancy is suspected but undiagnosed in adults. Biopsy of the mass itself should only be done as a last resort. PMID- 6922563 TI - Disorders of the salivary glands. PMID- 6922564 TI - Management of the patient with a thyroid mass. PMID- 6922565 TI - Airway obstruction in the pediatric patient. AB - In the newborn period and early infancy upper respiratory tract obstruction is commonly caused by congenital and neoplastic disorders, such as laryngomalacia, congenital subglottic stenosis, or brainstem anomalies. However, inflammatory causes of airway obstruction predominate in infancy and childhood. Laryngotracheal foreign bodies and trauma, on the other hand, have no age predilection. The diagnosis and therapy of airway obstruction in the pediatric patient are discussed. PMID- 6922566 TI - Hoarseness. Evaluation and treatment. PMID- 6922567 TI - Tonsils and adenoids. When is surgery indicated? AB - The efficacy of tonsillectomy and/or adenoidectomy in the management of urgent problems such as cor pulmonale, acute airway obstruction, or functional impairment of nasal respiration, speech, or swallowing is unquestioned. However, relative indications for surgery such as odynophagia, otalgia, or otitis media with effusion are more controversial. The limitations and risks of tonsillectomy and adenoidectomy in these patients are explored. PMID- 6922568 TI - Nasal and otologic manifestations of allergy. PMID- 6922569 TI - Evaluation and therapy of nasal obstruction. PMID- 6922570 TI - Otitis media. AB - Dysfunction of the eustachian tube is the underlying problem in all types of otitis media. Systemic antibiotics and careful follow-up are the treatment of choice for acute suppurative otitis media, whereas topical antibiotics with saline irrigation are used in patients with a chronic condition. Myringotomy and tube insertion may be required in patients with secretory otitis media that does not undergo spontaneous resolution. PMID- 6922571 TI - Diagnosis and treatment of idiopathic facial paralysis. AB - Bell's palsy is a diagnosis of exclusion; other causes of facial paralysis that might be confused with Bell's palsy should be considered in order that appropriate treatment for these conditions is not delayed. Diagnostic tests for Bell's palsy are presented. Prednisone is the recommended treatment for patients with complete facial paralysis; occasionally, selected patients may require surgical decompression. PMID- 6922572 TI - [The importance of the communication process in nursing practice]. PMID- 6922573 TI - [Plant medications of popular origin and their implication in the practice and teaching of nursing]. PMID- 6922574 TI - [Basic aspects of nursing care in South American pemphigus foliaceus]. PMID- 6922575 TI - [Assessing the newborn infant's vitality by Apgar score]. PMID- 6922576 TI - [Teaching of sexually transmitted diseases in the Graduate Nursing School of the city of Sao Paulo]. PMID- 6922577 TI - [Deficiencies in the fulfillment of basic psychosocial needs--perceptions of patients with infectious hepatitis confined in an isolation unit]. PMID- 6922578 TI - [Behavior of the hospitalized child: a parameter in nursing care]. PMID- 6922579 TI - [The cancer patient and society]. PMID- 6922580 TI - [Kallikrein-kinin system]. PMID- 6922581 TI - [Who is in charge of hospital hygiene?]. PMID- 6922582 TI - [Role and authority of the physician-hygienist in France]. PMID- 6922583 TI - [Experience of a nurse in charge of hygiene in France]. PMID- 6922584 TI - [The physician-hygienist in Belgium]. PMID- 6922585 TI - [Hospital hygiene: everyone's business]. PMID- 6922586 TI - [Role of the nurse in hospital hygiene in Belgium]. PMID- 6922590 TI - [Cleaning in hospitals. Qualitative and financial aspects]. PMID- 6922588 TI - [Jean Rostand days, Sevres: 18 and 19 February 1982. Foreword]. PMID- 6922589 TI - [Disposable uniforms in the operating room]. PMID- 6922587 TI - [The physician-hygienist in the Federal Republic of Germany]. PMID- 6922591 TI - [Technical health analyses in operating rooms (rooms with conventional climatization equipment]. PMID- 6922592 TI - [From hygiene to hygienist]. PMID- 6922593 TI - [Sterilization]. PMID- 6922594 TI - [Disinfectants and antiseptics: utility and costs]. PMID- 6922595 TI - [Infectious reactions and phlebitis with the Venflon catheter]. PMID- 6922596 TI - [Difficulties in the collection of information concerning cross infections]. PMID- 6922597 TI - [Disposal of hospital wastes: safety and costs]. PMID- 6922598 TI - [Conclusion of the Jean Rostand days]. PMID- 6922599 TI - [Role and power of the physician hygienist in hospitals: Geneva concept]. PMID- 6922600 TI - [Echography: principles, instruments. Value overseas]. PMID- 6922601 TI - [Radiology: improving technics]. PMID- 6922603 TI - [Radiologic exploration of the lung and the mediastinum]. PMID- 6922602 TI - [Oral cholecystography]. PMID- 6922604 TI - [Intravenous cholangiography]. PMID- 6922605 TI - [Tomography: principles, instruments, technics]. PMID- 6922606 TI - [Place and role of the nurse in an integrated program of development]. PMID- 6922607 TI - [The choice of health priorities for nurses in isolated posts]. PMID- 6922608 TI - [The evaluation process for nurses in isolated posts]. PMID- 6922609 TI - [Primary health care: an already ancient system of care]. PMID- 6922610 TI - [Choice between traditional and modern medicine in Togo]. PMID- 6922611 TI - [Primary health care: new creation or new approach?]. PMID- 6922612 TI - [The village health team : set up and follow up]. PMID- 6922613 TI - [Postmenopause and its complications]. PMID- 6922614 TI - [Treatment of confirmed menopause]. PMID- 6922615 TI - [Menopause: to better surmount a critical period]. PMID- 6922616 TI - [Nutritional health at fifty]. PMID- 6922617 TI - [At the perimenopause, women state the situation in group discussions]. PMID- 6922618 TI - [Premenopause]. PMID- 6922619 TI - [Listening to a patient]. PMID- 6922620 TI - [Chlamydia trachomatis infections]. PMID- 6922621 TI - [Concept of neonatology: opinion of professor Minkowski]. PMID- 6922622 TI - [Child care methods and working women]. PMID- 6922623 TI - [Menopause: critical period]. PMID- 6922624 TI - [Teachers' roles]. PMID- 6922625 TI - [What is a meeting?]. PMID- 6922626 TI - [Nursing care of the mute patient: case study]. PMID- 6922628 TI - [Remarkable people in Thai nursing]. PMID- 6922627 TI - [Duration of uninterrupted rest and sleep following open heart surgery]. PMID- 6922629 TI - [Nursing care of patients with increased intracranial pressure]. PMID- 6922630 TI - [Physiological and biological responses: clinical nursing research data]. PMID- 6922631 TI - [An application of Roy's adaptation model]. PMID- 6922633 TI - [Nursing care of patients with cleft lip and cleft palate]. PMID- 6922632 TI - [Patient charting: critical care of patients with tetanus]. PMID- 6922634 TI - [Problem patients or problem nurses?]. PMID- 6922635 TI - [Integrated health development]. PMID- 6922636 TI - [Who is who in nursing in Thailand?]. PMID- 6922637 TI - [Delegation problems]. PMID- 6922638 TI - [The respiration as a motor which maintains the hyperventilation syndrome]. PMID- 6922639 TI - [The child we cannot save]. PMID- 6922640 TI - [Intensive care in the hospital: the development of a research method for capacity and organizational problems]. PMID- 6922641 TI - [Vitamins. III. Food preparation and loss of vitamins]. PMID- 6922642 TI - [What is happening in primary care?]. PMID- 6922643 TI - [The elderly patient in the hospital: care for the future]. PMID- 6922645 TI - [The therapeutic environment]. PMID- 6922644 TI - [The Works Council in public health care. Does this institute still make sense?]. PMID- 6922646 TI - [Retrolental fibroplasia and measures for its prevention]. PMID- 6922647 TI - [Introduction of team nursing: with reference to Martin Boekholdt's thesis]. PMID- 6922650 TI - [Responsible nursing care]. PMID- 6922649 TI - [Jewish traditions in death and mourning]. PMID- 6922648 TI - [Society changes and medical technology encroaches ever more--how does the nurse react to this?]. PMID- 6922651 TI - [Nursing care of patients with Guillain-Barre disease in the acute stage]. PMID- 6922652 TI - [A critical reaction to a critical analysis]. PMID- 6922654 TI - [Love in old age]. PMID- 6922655 TI - [This is how patients can feel... the home alternative]. PMID- 6922656 TI - [Reduction in hospital beds, a good thing?]. PMID- 6922653 TI - [Being dependent upon health care]. PMID- 6922657 TI - Identifying areas of need for self-directed learning experiences. PMID- 6922658 TI - Creation of self-learning centers. PMID- 6922659 TI - Self-directed learning projects. PMID- 6922660 TI - Postorientation program for neurosurgical nursing: independent-individualized instruction. PMID- 6922662 TI - Mentorship in nursing--a path to self-directed learning. PMID- 6922661 TI - Simulation as a tool for learning. PMID- 6922663 TI - Use of self-learning tools for orientation. PMID- 6922664 TI - The design and use of self-instructional materials. PMID- 6922666 TI - [Components of the kallikrein-kinin system in atopic dermatitis]. PMID- 6922667 TI - [Indices of the activity of the kallikrein-kinin system in the glossalgia syndrome]. PMID- 6922668 TI - And research has a many-splendid range. PMID- 6922665 TI - [Metabolic function characteristics and respiratory pathology of premature infants]. AB - A total of 143 premature children of the first 3 months of life (the body weight upon birth 1200-2500 g) staying at a specialized hospital, and 28 children (the body weight upon birth 1100-2500 g) under 3 years staying at a pulmonological sanatorium were examined. Studies on enzymatic functions (uropepsin, glutathione, protease and lipase activity in the blood serum) revealed a decrease in adaptation processes in premature children with acute pneumonia, and during reconvalescence in children with hypotrophy. In premature neonates on formula feeding with a mixture of "Malyutka", the content of total lipids, cholesterol and phospholipids was lower than in children on natural feeding. The content of free fatty acids and acetone tended towards an increase during formula feeding. Pneumonia incidence in premature children was 4 times higher in the first year of life and 2 1/2-2 times higher in the second and third years of life, as compared to full-term babies. The respiratory diseases in premature children were followed by the asthmatic syndrome. The results obtained may be used for the development of dietetic management of premature children with pneumonia and hypotrophy. PMID- 6922669 TI - Resistance types in Enterobacter cloacae. Occurrence and resistance to Ampicillin, Carbenicillin, Cephalothin and Mecillinam. Transfer of ampicillin Resistance. AB - An investigation of the resistance types in Enterobacter cloacae is presented. The frequency of the different resistance types was determined. The strains were divided into three groups according to sensitivity to penicillin derivatives. The ampicillin-carbenicillin-sensitive (A-s/Ca-s) group 1 comprised 20% of the E. cloacae strains received in this laboratory. The ampicillin resistant carbenicillin-sensitive (A-r/Ca-s) group 2 comprised 38.5% of the strains and the A-r/Ca-r group 3 comprised 41.5% of the strains. Group 3 contained a high proportion of multi-resistant strains. The log 2 IC50 against ampicillin, carbenicillin, cephalothin and mecillinam was determined for 28 strains. The group 3 strains were more ampicillin-resistant than the group 2 ones. Group 1 and 2 did not differ as regards carbenicillin sensitivity. The cephalothin resistance increased from group 1 to group 2 and further on to group 3. Mecillinam sensitivity did not differ between the three groups. The ability to transfer ampicillin resistance was investigated in the 24 A-r strains. The 8 group 2 strains were not able to transfer resistance, while 9 of 16 strains in groups 3 could transfer A-resistance with frequencies ranging from 10-0.2 to 10-5.7. Resistance to sulphonamide, tetracycline and streptomycin was also transferred, often with the same frequency as the ampicillin resistance. PMID- 6922671 TI - Building a ladder. PMID- 6922672 TI - Handling methotrexate --a safety problem? PMID- 6922673 TI - Rapid desensitization. PMID- 6922670 TI - Looking at ladders. PMID- 6922674 TI - Positioning as treatment for infant gastroesophageal reflux. PMID- 6922676 TI - Promoting wound healing. PMID- 6922675 TI - Prescribing patterns of nurse practitioners. PMID- 6922677 TI - Wound healing mechanisms. PMID- 6922679 TI - Sarcoidosis: a multisystem disease. PMID- 6922678 TI - Wound healing: influencing repair and recovery. PMID- 6922680 TI - An experience with a joint appointment. PMID- 6922681 TI - Therapeutic apheresis. PMID- 6922683 TI - A little nurse--and 20 years later. PMID- 6922682 TI - The legal side: failure to communicate. PMID- 6922684 TI - Analytic epidemiologic methods for research on nosocomial infections: definitions and examples. AB - Two types of epidemiologic studies are presented: the cohort study and the case control study. The fundamentals distinction between the two methods is in the definition of the population groups for study. The cohort approach identifies groups with different exposure histories, whereas the case-control approach begins with groups with different health and disease characteristics. The investigation in the cohort method involves collection of data on the disease experience of the various exposure groups from date of exposure to some later follow-up date. Data collection in the case-control study is concerned with the exposure history prior to the date of the identified health and disease status. Both approaches are satisfactory in general, but either may have distinct advantages in a given study, depending chiefly on the frequencies of exposure and disease and on the nature of biases inherent in available data. PMID- 6922685 TI - Factors influencing handwashing behavior of patient care personnel. AB - Factors that are important in influencing individuals to wash or not wash their hands were studied in 193 health care personnel. The most important factor favoring handwashing (HW) was the prevention of spread of infection among patients; the most important factor against HW was busy-ness. Physicians reported HW significantly less frequently than did nurses (p = 0.04). Individuals who washed infrequently, less than eight times per day, placed significantly more value on detrimental effects of frequent HW on their own skin and on the HW practices of their work colleagues than did individuals who washed frequently, more than 16 times per day (p less than 0.005). Frequent and infrequent washers did not differ significantly in their values regarding the factors favoring HW. Identifying factors that are determinants of whether one decides to wash one's hands or not are important in planning intervention strategies to improve practice. It appears that more emphasis should be placed on minimizing deterrents (especially detrimental effects on skin and peer pressure) rather than on emphasizing the importance of HW. PMID- 6922687 TI - Nine notables offer advice to young nurses. PMID- 6922686 TI - ANA contacts lighten loneliness, give support. PMID- 6922688 TI - Four nurses describe 'dramatic' changes in education. PMID- 6922689 TI - Career variety, flexibility attract students to nursing. PMID- 6922690 TI - Deficiency of fat-soluble vitamins in treated patients with pancreatic insufficiency. AB - Deficiency of fat-soluble vitamins (A,D,E, and K) was evaluated in 15 patients with exocrine pancreatic insufficiency secondary to chronic alcoholic pancreatitis. Mild to moderate steatorrhea was present in all patients despite oral pancreatic enzyme therapy for 27 +/- 4 months (mean +/- SE). Deficiency of a single fat-soluble vitamin was seen in six patients and deficiency of two fat soluble vitamins was seen in two patients. One patient was deficient in three fat soluble vitamins. Deficiency of vitamins A and E was most frequent. Treatment with specific vitamin supplements resulted in correction of these vitamin deficiencies. These data suggest that deficiency of a single or multiple fat soluble vitamins is frequent even in treated patients with pancreatic insufficiency. PMID- 6922692 TI - The role of broad-spectrum antibiotics and diagnostic problems in urinary tract infections. PMID- 6922691 TI - In vitro activity of antibiotics commonly used in the treatment of otitis media against Streptococcus pneumoniae isolates with different susceptibilities to penicillin. AB - Susceptibilities of 82 clinical isolates of Streptococcus pneumoniae, including 25 from the middle-ear fluid, were evaluated against antibiotics commonly used in the treatment of acute otitis media. Potentially significant resistance occurred in 6% of the isolates to erythromycin and an erythromycin-sulfisoxazole combination. The combination of trimethoprim and sulfamethoxazole was synergistic for 95% of the isolates. Only 2.5% of all of the isolates were resistant to both erythromycin-sulfisoxazole and trimethoprim-sulfamethoxazole. The presently used drug regimens should be effective against the majority of S. pneumoniae isolates in otitis media. PMID- 6922694 TI - Care and support of victims of prejudice. PMID- 6922693 TI - Concern - the mandate of the Christian nurse. PMID- 6922695 TI - Cultural influences on birth practices in Northern Australia amongst Aboriginals. PMID- 6922696 TI - Cultural influences in birth practices in Papua New Guinea. PMID- 6922697 TI - Cultural influence on birth practice in Hong Kong. PMID- 6922699 TI - The role of the professional in the care and protection of the child. PMID- 6922698 TI - Rape Enquiry Unit. PMID- 6922700 TI - Care and counseling of adults at risk. PMID- 6922703 TI - The effectiveness of an eight hour/ten hour day shift rotation. PMID- 6922702 TI - The purification and properties of the second component of guinea-pig complement. AB - A method has been developed for the purification to homogeneity of guinea-pig complement component C2. Contrary to previous reports, guinea-pig C2 is a single polypeptide chain with apparent mol.wt. of 102000, the same as human C2. It is cleaved by C1s to yield fragments C2a (apparent molwt. 74000) and C2b (apparent mol.wt. 34000). The amino acid composition and N-terminal sequences of these fragments are similar to those of human C2a and C2b. Human and guinea-pig C2 show more extensive sequence homology to Factor B than previously identified. The known homology around the sites of cleavage by C1s and Factor D has now been extended by a stretch of ten identical or conservatively substituted residues. Sequence homology has now been identified at the N-terminal of C2b and Factor Ba. The properties of the classical-pathway C3 convertases assembled from human C4b, C1s and human or guinea-pig C2 have been compared. The rates of cleavage of human and guinea-pig C2 by C1s (and therefore the rates of assembly of the C3 convertases) are similar. The rate of decay of the activity of the C3 convertase formed from guinea-pig C2 is 10-fold lower than for human C2. This greater stability reflects a higher affinity of guinea-pig C2a for human C4b. The presence of C2b is not necessary for C3 convertase activity. PMID- 6922701 TI - Complement proteins C2, C4 and factor B. Effect of glycosylation on their secretion and catabolism. AB - Tunicamycin, an inhibitor of N-acetylglucosaminylpyrophosphopolyisoprenol dependent glycosylation, was used to study the effect of glycosylation on the synthesis, post-translational modification, secretion and function of the complement proteins that are associated with the major histocompatibility complex in humans, mice and guinea pigs. Tunicamycin blocked glycosylation of pro-C4, C2 and factor B and inhibited secretion of the corresponding native complement proteins synthesized by guinea-pig peritoneal macrophages in tissue culture. In addition, underglycosylated pro-C4 was more rapidly catabolized intracellularly than the corresponding fully glycosylated pro-complement protein. C4 protein secreted by cells incubated with tunicamycin had approximately the same specific biological activity as the protein obtained from control culture media, suggesting that carbohydrate is not required for its activity in immune haemolysis. Direct studies of carbohydrate incorporation and the tunicamycin effect suggested an unequal distribution of sugar among the C4 subunits, with maximal incorporation of carbohydrate into alpha-, and less into the beta-chain of the native protein. PMID- 6922704 TI - Patient feelings about illness: do they affect compliance with the therapeutic regimen? PMID- 6922705 TI - Plasma treatment of acute renal failure in four pediatric patients. PMID- 6922707 TI - Effect of high sodium dialysate on blood pressure and interdialysis weight gain. PMID- 6922709 TI - Nursing care of the chronic renal failure patient with sexual dysfunction. PMID- 6922706 TI - The forgotten team member. PMID- 6922708 TI - The relationship of health belief motivations, health locus of control and health valuing to dietary compliance of hemodialysis patients. PMID- 6922710 TI - A comparative study of women choosing two different childbirth alternatives. PMID- 6922711 TI - New motherhood: a time of crisis? PMID- 6922712 TI - Education for vaginal birth after cesarean. PMID- 6922713 TI - An answer to childbirth educator burn-out. PMID- 6922715 TI - The importance of maternal nutrition in the weeks before and after conception: another viewpoint. PMID- 6922714 TI - The importance of maternal nutrition in the weeks before and after conception. PMID- 6922716 TI - Use of water in labor. PMID- 6922718 TI - Maternity care in China: report of a 1982 tour of Chinese medical facilities. PMID- 6922717 TI - Prenatal exercise. PMID- 6922719 TI - Roundtable. II. Organogenesis, fetal growth, and food. PMID- 6922720 TI - Maternal lateral preference at first contact with her newborn infant. PMID- 6922721 TI - Infant feeding practices of middle-class breastfeeding and formula-feeding mothers. PMID- 6922722 TI - Nutrition, family planning, and health promotion: the Guatemalan program of primary health care. PMID- 6922723 TI - Purification and properties of human low molecular weight kininogen. AB - A three-step isolation procedure has been developed for human low molecular weight kininogen resulting in a 385-fold purification of the protein from plasma with an accumulative yield of 8.4%. Human low molecular weight kininogen is a single-chain glycoprotein of apparent molecular weight of 68,000 with a blocked amino-terminus. In the absence of dissociating agents, low molecular weight kininogen reversibly forms homo-oligomers with apparent Mr 185,000 (dimer) to 780,000 (decamer). Limited proteolysis of low molecular weight kininogen by tissue kallikrein liberates kinin and results in the formation of a two-chain molecular with an Mr 62,000 heavy chain of apparent Mr 4000. PMID- 6922724 TI - Isolation and characterization of an acyl carrier protein from pigeon liver fatty acid synthetase by controlled proteolysis with elastase. AB - Controlled proteolytic cleavage of 4'-phospho[14C]pantetheine-labeled pigeon liver fatty acid synthetase generates two 4'-phospho[14C]pantetheine-labeled peptides, Ec1 and Ec2. These are separated from each other and the core enzyme by gel permeation chromatography on a Sephadex G-75 column. The two radioactively labeled peptides constitute 50% of the radioactivity initially present in the 4' phospho[14C]pantetheine-labeled fatty acid synthetase. The remaining label in the core enzyme is released quantitatively by proteolytic cleavage with trypsin. The molecular weights of Ec1 and Ec2 peptides, as determined by size exclusion chromatography and SDS-polyacrylamide gel electrophoresis, are 12000 and 6000, respectively. Both the higher and lower molecular weight peptides are homogeneous with respect to size and charge, as shown by polyacrylamide gel electrophoresis in the presence and absence of SDS. The higher molecular weight peptide, Ec1, is characterized as an acyl carrier protein by the transacylation reaction between the unlabeled Ec1 peptide and radioactively labeled acetyl- and malonyl-CoA. Since Ec2 peptide also contains the prosthetic group present in the Ec1 peptide, the Ec2 peptide appears to result from the proteolytic cleavage of the higher molecular weight peptide, Ec1. Amino acid composition of the acyl carrier protein shows the presence of 1 mol of 4'-phosphopantetheine per mol of protein. 2 mol of acyl carrier protein are present per mol of the fatty acid synthetase. The amino acid analysis is in good agreement with the molecular weight of the Ec1 peptide, as determined by gel filtration and SDS-polyacrylamide gel electrophoresis. N Terminal amino acid analysis of this peptide shows the presence of an arginine residue. PMID- 6922725 TI - [Use of a chromatographic method for determining kallikrein and prekallikrein in dog blood serum]. AB - The authors determined the conditions of chromatography to be used for determination of prekallikrein and kallikrein in the dog blood serum. The enzyme and its precursor do not adsorb on DEAE-Sephadex A-50 in a 0.02 M phosphate buffer, pH 7, containing 0.15 M NaCl, and thus their quantity can be determined in a non-adsorbed protein fraction from the rate of hydrolysis of N-benzoyl-L arginine ethyl ester before and after exposure to trypsin. In 1 ml of the dog blood serum, kallikrein activity ranged from 0 to 60 mE, while prekallikrein activity from 127 to 187 mE. PMID- 6922726 TI - [Antienzyme function of the lungs in acute pancreatitis]. AB - Experiments were made on 22 anesthetized dogs to examine the systemic and pulmonary hemodynamics, gas exchange and metabolic pulmonary function in pancreonecrosis. Metabolic pulmonary function was evaluated from arteriovenous difference according to elastase. In the early stages of experimental pancreatitis, the lungs were shown to inactivate elastase and to function as an active metabolic organ. Then depletion of antienzymatic pulmonary function is observed, which is accompanied by decompensation of the hemodynamics and gas exchange. Abnormality of antienzymaztic pulmonary function plays an important role in the pathogenesis of acute pancreatitis. PMID- 6922727 TI - Televised nursing education in British Columbia. PMID- 6922728 TI - The information revolution: where does it leave nursing. PMID- 6922729 TI - Telehealth: making health care truly accessible in the north. PMID- 6922730 TI - Computers and patients: the user system. PMID- 6922732 TI - The VDT controversy. PMID- 6922731 TI - York Central Hospital. Interview by Leo Charbonneau. PMID- 6922733 TI - Implementation of a unit dose medication system: making change strategy relevant throughout a hospital. PMID- 6922734 TI - Epidurals in labor and delivery rooms. PMID- 6922735 TI - Does diabetic control really make a difference? PMID- 6922736 TI - [Alkylamides of N-acyltripeptides. New inhibitors of pancreatic elastase and possible uses in vivo]. PMID- 6922738 TI - [In search of gentleness in nursing - the depth of thinking by the sick]. PMID- 6922737 TI - [Starting point in teaching nursing - encounter with the nursing theories in the past 10 years. (4)]. PMID- 6922739 TI - [On nursing and nursing education (10) - the current status of practical nursing education and its problems (2)]. PMID- 6922740 TI - [Nursing and the daily life of a patient - an experience of a nurse as a patient. (2)]. PMID- 6922741 TI - Old people - aspects of caring: 'It's nice to know that someone cares.'. PMID- 6922742 TI - What's in a name? PMID- 6922743 TI - Move a muscle every day! PMID- 6922744 TI - Old people - aspects of caring: Mrs Brown. PMID- 6922745 TI - Community specialists. PMID- 6922746 TI - Torts: doctrine of precedent. PMID- 6922748 TI - Nosocomial infection in the intensive care unit. PMID- 6922747 TI - Pain: what do we really know about it? PMID- 6922749 TI - Hypertension update. CEU home study. PMID- 6922750 TI - Temperament: concepts, issues and problems. AB - There are marked individual differences in children's temperamental styles-- differences thought to be constitutionally determined in part. The importance of temperamental features is evident in their links with various forms of psychopathology and in their effects on the manner in which other people respond to the child. For these and other reasons it has rightly come to be accepted that greater attention needs to be paid to temperamental issues in consideration of the processes of development, children's responses to stress situations, and the genesis of emotional, behavioural and learning disorders. However, major conceptual, methodological and theoretical problems remain. Problems of measurement are considered in terms of the relativity of measures, whether or not to take social context into account, the functional equivalence of measures at different ages, the circumstances to use in assessing temperament, the choice of measuring instrument and the categorization of temperamental features. The issues involved in the meaning of temperamental differences are discussed with respect to consistency, developmental change, genetic influences, brain damage and mental retardation, sex differences and the mechanisms by which temperamental variables exert their effects. PMID- 6922751 TI - Temperamental differences in infants and young children. PMID- 6922752 TI - Intrinsic determinants of temperament. AB - Infant twins have been recruited to participate in a longitudinal assessment of temperament, beginning at three months of age. The twins are brought into a structured laboratory setting and are videotaped as they interact with the mother, with staff personnel, and with each other. The infant's temperament is rated from the videotapes, and additional data are obtained by having the parents fill out the Infant/Toddler Temperament Questionnaire at each visit. A neonatal assessment has also been done for most twins to obtain initial measures of irritability, reactivity and soothability. Monozygotic twins showed high concordance for irritability as neonates, and for ratings of emotional tone at 12 months. Monozygotic twins also tended to show synchronized patterns of change between ages. The questionnaire ratings correlated significantly with the laboratory ratings at six and 12 months, and this convergent linkage between two sources argues for a core temperament profile that manifests itself with some consistency. PMID- 6922753 TI - Influence of genetic factors on temperament development in early childhood. PMID- 6922754 TI - Behavioural genetics and temperament. AB - Three recent developments in behavioural genetics are relevant to temperament research. First, the search for genetic influences on temperament has been frustrated by the finding that twin studies using self-report and parental rating instruments detect a genetic influence for all personality traits whereas twin studies using objective assessments rarely find a genetic influence. Secondly, environmental influences salient to temperament appear to operate in such a way as to make members of a family (siblings, for example) as different from one another as are individuals in different families. The importance of such 'E1', or non-shared, environmental influences suggests the need for studies of more than one child per family. Thirdly, adoption studies are needed to complement the extensive research on temperament in twins. In addition to its usefulness in isolating genetic influences, the adoption design can study environmental influence devoid of the confounding effects of hereditary influences; it can also isolate interactions between genotypes and environments. Preliminary results from the Colorado Adoption Project show little relationship between the temperaments of adopted and non-adopted one-year-olds and the personality characteristics of thier parents. Measures of the home and family environment did not relate to infant temperament, and no genotype-environment interaction was detected. PMID- 6922755 TI - Temperament and follow-up to adulthood. AB - A follow-up of the New York longitudinal study at the 18-22-year period has been completed. Only one of the 133 subjects was not interviewed and evaluated. A temperament questionnaire for this age period has also been developed and given to 70 of the subjects. From the interview, ratings of temperament, adjustment and clinical psychiatric status were made. Statistical correlations showed significant relationships between 'difficult-easy' temperament at three and five years of age and early adult 'difficult-easy' temperament, adjustment, and presence or absence of a clinical psychiatric diagnosis. The importance of qualitative analyses of idiosyncratic developmental factors in individual cases is emphasized. PMID- 6922756 TI - Personality development and temperament. AB - This paper identifies a number of problems that emerge in our attempts to trace a developmental linkage between early-appearing individual differences in temperament and later personality. It is suggested that the major problem is that of inadequate theory, from which it follows that there will be problems of definition and methodology. Attention is also drawn to difficulties associated with the concept of 'development'. Certain early-appearing individual difference are identified, for which there is accumulating evidence of a genetic or constitutional basis. Further, these appear to show some stability and are accorded an important role in a number of theories, especially that of Eysenck. It is suggested that his approach, despite its many limitations, is worth further exploration. PMID- 6922758 TI - Temperament and minor physical anomalies. AB - Minor physical anomalies (MPAs) are an index of deviant embryological development due to genetic defects of insults to the fetus. A brief 10-minute examination an an individual makes it possible to establish a count that shown highly stable individual differences from the newborn period up to age seven years, the latest age studied longitudinally. For males, high MPA counts in the newborn period have shown strong predictive relationships to preschool temperament factors such as short attention span, high activity level, and aggressive-impulsive behaviour. For females, high anomaly scores showed relationships to short attention span and to inhibition. Such findings are in contrast with inconsistent results from genetic studies and with infrequent, weak relationships of neonatal variables to later behaviour. These results from the Bethesda longitudinal study have been confirmed in most cases by several cross-sectional studies. Sex differences in behaviour, usually considered to result from differential sex-role training, disappear in preschool samples from which high MPA individuals have been removed, but are much more pronounced than usual in samples with high MPAs. PMID- 6922757 TI - Clinical use of temperament data in paediatrics. AB - Temperament data can aid the clinician in fostering parent-child relationships on three levels. First, general educational discussions about temperament between the clinician and parents provide background information, which increases parents' awareness and understanding of individual differences. Second, identification of the temperament profile of the particular child provides the parents with a more organized picture of the child's behavioural style and of possible distortions in their perceptions of its. This is primarily useful to the clinician when the child is rather difficult or when, for example the mother's perception of the child makes the child seem more difficult than her own ratings suggest. This clarification process may provide parents with enough insight for them to make their own shifts in interaction patterns. Third, the clinician may attempt to influence the temperament-environment interaction, when its dissonance is leading to reactive symptoms, by suggesting alternative methods of parental management. If this is successful, the stress of the interaction should diminish and the reactive symptoms disappear. At the same time parents the teachers must learn to live in a more tolerant and flexible manner with the child's relatively less changeable temperament. PMID- 6922759 TI - Infant temperament, maternal mental state and child behaviour problems. AB - In a longitudinal study of firstborn children, interview-based measures of temperament were obtained when the infants were aged four months. From the individual items an 'easy-difficult' scale was constructed. The scale showed a fair internal consistency and reasonable test/retest reliability, and the obtained scores appeared to be independent of previous and current maternal attitudes and mental state. A wide range of scores was obtained. Four-month temperament, as reflected on this scale, related to the presence of behavioural problems when the children were aged 42 months, with 'difficult' children developing higher rates of problems. Problems at 42 months also related strongly to the mother's mental state at the time, with the children of depressed mothers showing more problems. When all three items--four-month temperament, 42-month behavioural problems and 42-month maternal depression-were examined, a strong interaction effect was found. Maternal depression was associated with behavioural problems only if the child had been in the extreme quartiles on the temperament measure. Some evidence suggested that an infant's temperament could affect its mother's later mental state. PMID- 6922760 TI - On the continuity, change and clinical value of infant temperament in a prospective epidemiological study. AB - The temperament of 1855 children born in Helsinki during 1975-76 was recorded at the age of 6-8 months by parental questionnaires. In 1980-81 the continuity of temperamental dimensions was studied in a group of these children by using a temperament questionnaire for 3--7-year-old children. In addition, the clinical usefulness of infant temperament was assessed by analysing the infant temperamental dimensions used was almost negligible, because less than 10% of the total variance of each dimension could be explained by the corresponding dimensions at the infant age. The clinical usefulness of infant temperament questionnaires in prospective epidemiological studies was supported by the observation that children with later paediatric problems (behavioural problems, colic spasms, accidents) had had significantly different temperamental styles at the infant age from those without problems. The results support the importance of negative mood and high intensity of infant's behavioural style as risk factors for later paediatric problems. PMID- 6922761 TI - Temperamental patterns in aggressive boys. AB - Four groups of aggressive body ( and one group of controls) were studied, on the basis of: clinical referrals to a hospital clinic; teacher reports of assaultive behaviour in school; teacher reports of severe aggressive behaviour in school; and peer reports of aggressive behaviour. Questionnaire techniques were used to study behaviour and temperament. The last three groups proved to have rather similar patterns of behaviour and temperament and, therefore, they have been combined to give rise to an 'any school criterion' group. We compared three main groups: (i) clinical referrals; (ii) 'any criterion' (school-identified); and (iii) controls. On behaviour, the clinical group had the most adverse scores, especially on antisocial behaviour. The school-identified group also had a higher score than the controls on this dimension, and differed in degree from the clinical referral group. On temperament, the clinical referral group had a significantly more adverse score on all dimensions than both the controls and the 'any criterion' group. The 'any criterion' group scores were intermediate between the other two sets of scores. The differences on temperament between the control and the 'any criterion' groups appeared to be one of degree but not of type. Moreover, no specific type of temperament was associated with the different kinds of aggression we have studied. Principal components analysis supports the notion of no qualitative temperamental differences between the 'any criterion' and the control groups. PMID- 6922762 TI - Children's temperament and teachers' decisions. AB - Findings from a series of studies of the educational implications of children's temperament patterns are summarized. This research has been guided by three hypotheses: (1) that there are real individual differences among children in behavioural styles or temperament; (2) that individual variations in children's patterns of temperament influence the nature of their interpersonal interactions; and (3) that perceived variations in temperament become especially powerful influences on adults' decisions when children are handicapped or at risk. Based on these assumptions, the study of temperament has followed two primary lines of research. in the first we have attempted to delineate the hypothesized link between perceived temperament variations and teachers' educational decisions. In the second we have attempted to determine the influence of perceived temperament variations on children's personal-social competence within intervention settings. Findings support a relationship between children's temperament and their achievement and adjustment in school. Temperament was related to measures of children's academic performance and to teachers' perceptions of other aspects of children's school adjustment. Further, teachers' ratings of children's temperament were related to their classroom management decisions. The results suggest that teachers' responses to children in the classroom are mediated by their perceptions of the children's temperament. PMID- 6922763 TI - Temperament: a consideration of concepts and methods. AB - This paper discusses conceptual issues and begins with a consideration of definitions of temperament. It is suggested that the purposes for which temperament has been studied have, to some degree, dictated methods used and inferences drawn. Those psychopathologists interested in the relationship between temperament and psychiatric disorder, or emotional and behavioural disturbance, have tended to use different methods from those more concerned with delineating the structure of personality. Some issues and problems are common to both approaches, e.g. the definition of behaviour reflecting temperament in terms of style rather than content. Other issues, such as the difficulty involved in drawing a clear distinction between temperamental attributes and mental disorders, are restricted to one approach. The relative contribution of gentic and environmental effects is of interest to both psychopathologists (who wish to examine this issue in relation to the development of the individual), and to psychologists (who are usually more concerned with populations or aggregate effects). The application of biometric genetic models might clarify this issue, and various suggestions are made regarding steps that need to be taken if such models are to be successfully applied. PMID- 6922764 TI - Temperament and relationships. AB - Temperamental characteristics of preschool children were related to relationships, mothers' mood, and children's feelings towards family members. Active scores were correlated with some problem behaviour and with negative aspects of interactions with mother and father. Active children felt themselves to be independent, while Timid children did not. Timid children had relatively more acute illnesses and worries and fears. Difficult scores were correlated with problem behaviour and with negative aspects of all the types of interaction assessed: mother-child, mother-father, father-child, and sibling-child. Furthermore, the more Difficult the child, the more Anxious, Outwardly Irritable, and Inwardly irritable the mother. In turn, Difficult children expressed relatively few positive and dependency feelings towards their mothers, and more negative feelings towards themselves. PMID- 6922765 TI - Temperamental characteristics of 3--4-year-olds and mother-child interaction. AB - Comparisons are presented between the temperamental characteristics of preschool age children from two-child families and aspects of mother-child interaction observed in the home. The data were collected when the children were 42 months old (n = 45) and 50 months old (n = 37). Although few behavioural items were directly relevant to temperament, several temperamental characteristics (Moody, Intense, Shy, Assertive) had behavioural correlates of a type that might be expected. Active and Irregular also showed meaningful patterns of correlations. Unmalleable, Dependent and Attention span did not. However, although there were no sex differences in the ratings of temperamental characteristics, the correlations between particular characteristics and behavioural items sometimes differed markedly between boys and girls, and also between firstborns and secondborns. Thus comparisons between temperamental characteristics and the behavioural data involving the whole sample were sometimes less revealing than those concerning each sex or sibling-status group separately. PMID- 6922766 TI - Temperamental differences, family relationships, and young children's response to change within the family. AB - In a longitudinal study of 40 firstborn children, temperamental differences between the children were found to be linked to the emergence and persistence of anxious and unhappy behaviour over the year following the birth of a sibling. Direct observation showed that these temperamental differences were also associated with differences in the children's interactions with their mothers, and with differences in their behaviour towards their mothers when mother and sibling were interacting. In contrast, the wide range of individual differences in the behaviour of the firstborn children to their siblings was not associated with temperamental difference between the children. There was some evidence for continuity in temperamental differences between the assessments before and after the sibling birth, but in many children the behavioural changes were marked. These findings underline the clinical significance of temperamental differences in children's vulnerability to changes in family life; they also indicate that 'temperament' should be considered not as a characteristic of the child independent of his or her particular family relationships but, on the contrary, as closely linked to his or her relationship with the mother, and as susceptible to the effects of marked change in the family environment. PMID- 6922767 TI - The untapped source of funds for nursing education. PMID- 6922768 TI - Dialysis disequilibrium syndrome: a critical care nursing challenge. PMID- 6922769 TI - Resolving ethical dilemmas in critical care. PMID- 6922770 TI - Pulmonary artery pressure and position changes in the critically ill adult. PMID- 6922771 TI - Getting your input into unit design. PMID- 6922772 TI - Should new nursing graduates be used in critical care? Yes. PMID- 6922773 TI - Should new nursing graduates be used in critical care? No. PMID- 6922774 TI - Scheduling educational programs for the night shift. PMID- 6922775 TI - Tax changes of interest to critical care nurses. PMID- 6922776 TI - Developing an article using the nursing model. PMID- 6922779 TI - How to develop a support group for families of open heart surgery patients. PMID- 6922778 TI - Capturing the leadership potential of critical care nurses. PMID- 6922781 TI - Extracorporeal membrane oxygenator support of the infant. PMID- 6922780 TI - Twenty five ways to avoid writer's block. PMID- 6922782 TI - The three dimensions of your critical care practice. PMID- 6922777 TI - Pneumatic anti-shock suits: when and how to use them. PMID- 6922783 TI - Nursing care of mitral valve prolapse. PMID- 6922784 TI - Assessment and evaluation of the paradoxical pulse. PMID- 6922786 TI - Twelve ways to save time in critical care. PMID- 6922785 TI - Prostaglandin E1 treatment for neonatal heart defects. PMID- 6922787 TI - Staff involvement in quality assurance. PMID- 6922788 TI - Using an OR activity log. PMID- 6922789 TI - A guide to informed consent. PMID- 6922790 TI - Surfactant treatment in experimental hyaline membrane disease. AB - Premature newborn rabbits obtained by hysterotomy on day 27 of gestation were ventilated artificially under standardized conditions, serving as experimental model of neonatal hyaline membrane disease. Natural surfactant with a phospholipid concentration of approximately 8 mg/ml was administered as 50 microliter doses after 10 min of ventilation and at subsequent 30-min intervals. Initial values for lung-thorax compliance were significantly improved following two doses of surfactant, whereas compliance levels of non-treated littermates remained unchanged. Treatment with surfactant resulted in increased alveolar air expansion. Bronchiolar epithelial lesions were present in both surfactant-treated animals and controls, but the severity of these lesions was clearly reduced after surfactant treatment. We conclude that surfactant substitution is an effective treatment in experimental hyaline membrane disease, even when given after an initial period of artificial ventilation. PMID- 6922791 TI - Relationship between the renal kallikrein activity and the urinary excretion of kallikrein in rats. PMID- 6922792 TI - [Differential diagnosis and treatment of acute bacillary dysentery]. PMID- 6922793 TI - [Cardiomyopathies]. PMID- 6922794 TI - [Current diagnostic and treatment principles of extrauterine pregnancy]. PMID- 6922796 TI - [Therapeutic and prophylactic nutrition in industry]. PMID- 6922795 TI - [Lymphogranulomatosis]. PMID- 6922799 TI - [Vomiting of pregnant women]. PMID- 6922798 TI - [Research work in the subject study groups of medical schools]. PMID- 6922797 TI - [Therapy in acute intestinal infections in young children]. PMID- 6922800 TI - [Acute trichomonal urethritis and colpitis]. PMID- 6922801 TI - [Exudative pleurisy]. PMID- 6922804 TI - The role of concepts and theories in research. PMID- 6922802 TI - [Osteochondropathy of the tibial tuberosity: Osgood-Schlatter disease]. PMID- 6922803 TI - A day in the life of a certified nurse midwife. PMID- 6922805 TI - Evaluation methods in continuing education in nursing. PMID- 6922806 TI - [Does fetal oxytocin initiate human labour? A hypothesis]. AB - The concentration of specific oxytocin receptors increases during pregnancy and reaches a maximum at term after the onset of spontaneous labour. This constitutes a biochemical explanation for the well-known increase of oxytocin sensitivity during pregnancy. Oxytocin receptors were also found in human decidua and their concentration increased similarly. Based on these results the hypothesis was set up that oxytocin leads to an increase in prostaglandin production though specific receptors in decidua. Under specific incubation circumstances oxytocin indeed increased prostaglandin E and prostaglandin F synthesis of decidual tissue. In induction of labour with oxytocin PGF-levels in the maternal peripheral plasma increased significantly in all women in whom induction was successful. Since it is known that the fetus secretes considerable amounts of oxytocin in case of labour of spontaneous onset the hypothesis was set up that fetal oxytocin may initiate human labour by the mechanisms described above. PMID- 6922808 TI - [Bowen's disease of the nipple]. AB - The clinical and morphological features of Bowen's disease of the nipple are reported. The 51 year old patient had an eczema type change of the left nipple for over 1 year. The microscopic evaluation of the extensive segmental resection showed Bowen's disease of the nipple. Paget's disease was excluded with certainty. As far as the authors know this is the first case of Bowen's disease of the nipple reported. The treatment of choice is extended segmental resection. With this treatment the prognosis of Bowen's disease of the nipple appears to be favourable. PMID- 6922807 TI - [Screening of diabetes in pregnancy. Standard value criteria for 50g-oGTT and fasting blood sugar as simple screening parameter with high accuracy]. AB - Standard value criteria are presented on the basis of 1313 50g-oGTT for assessing carbohydrate metabolism in pregnancy (after the 26th week). The causes of the pregnancy-specific low levels are discussed. The difficulties in comparing these values with those reported by other authors, are pointed out. The authors deal extensively with the various load doses, conditions determining the decrease and glucose determination methods, and attempt to correlate the results with other data. The authors recommend fasting blood sugar values as a simple screening parameter for selecting those pregnant women on whom oGTT would be performed. This results in almost 90% coverage for pathological carbohydrate tolerance, i.e. a result which is superior to the results obtained with all other methods communicated so far. With this method, every 15th pregnant woman is required to undergo a costly and time-consuming test. PMID- 6922809 TI - [Fibromatosis of the female breast]. PMID- 6922811 TI - [The Meckel-syndrome in a newborn]. PMID- 6922810 TI - [Operative correction of a urogenital malformation with persistent cloaca]. AB - A case of malformation of the urogenital system with a persistent urogenital sinus and a cloaca is reported. There was unilateral agenesis of the kidney, megaureter and a double ureter with an ureteral orifice into the vagina and the clitoris. There was a double uterus and vagina with an orifice into the terminal gut. The patient had chronic recurrent urinary tract infections which required a colostomy during childhood. The operation largely restored a normal urogenital area and a functional anus. PMID- 6922812 TI - [A foetus papyraceus in twin birth at term]. PMID- 6922813 TI - [Cytology of adenocarcinoma in situ of the uterine cervix]. PMID- 6922815 TI - [Disseminated peritoneal leiomyomatosis. Light and electron microscopic study]. AB - The rare case of disseminated peritoneal leiomyomatosis is reported. A 41 year old non-gravid patient had a laparotomy for uterine fibroids and numerous subperitoneal nodules were found in the abdominal cavity. The light and electron microscopic examinations showed disseminated peritoneal leiomyomatosis. The nodular proliferation of the sub-peritoneal stroma is characteristic for this disease. The patient is free of problems three years following the initial diagnosis of disseminated peritoneal leiomyomatosis. PMID- 6922816 TI - [Papillomatous cystic para-ovarian blastoma with lymphoid stroma]. AB - The morphological and clinical findings of a papillomatous cystic para-ovarian blastoma are reported. A 48-year old patient had a hysterectomy and partial right salpingectomy in 1974. In 1980 at now age 54 the remaining appendages right and left were removed. The histologic examination of the remaining right appendages showed in the mesorovarium a 17 x 15 x 12 mm diameter papillomatous cystic para ovarian blastoma with abundant formation of psammoma bodies and numerous lymph follicles in the stroma. The left ovary showed a papillomatous, fibromatous, serous cystadenoma. The aetiology of the papillomatous cystic para-ovarian blastoma is unknown. A relationship to the prior right salpingectomy is unlikely. The concommitant findings of a papillomatous fibromatous serous cystadenoma of the left ovary is suggestive of a tumour diathesis of the mesonephric system in this case. PMID- 6922814 TI - [Positive cytological smears in adolescents and young women]. AB - In a large laboratory for cytology PAP-smears from 98221 teenagers and young women aged 15-25 years old (5,2% of the complete material) were examined from 1967-1980. Positive PAP-smears (PAP III D, IV a/b and V) were found in 627 of all cases (0,63%). In the group of young women (15-25 years) positive PAP-smears increased from the first to the following 7 years. In a group of women aged more than 25 years, positive results decreased. The so-called juvenile dysplasia (PAP III D, 487 of all cases) must not be treated, controls in short intervals (3-4 months) are necessary. The results of this paper point out that young women should undergo routine check-ups from the age of 18. PMID- 6922817 TI - [A new, sensitive haemagglutination inhibition test for the specific detection of human choriongonadotropine (HCG) in urine]. AB - The reliability and clinical usefulness of a new pregnancy tube test with a sensitivity of 125 IU HCG/l was tested on 1142 urine samples. No false-negative results and 0.6% false-positive results were observed; a crossreaction with LH was seen above 1400 IU LH/l. In all cases of ectopic pregnancies (n = 49) the test yielded a positive result. In daily urine samples, collected during the luteal phase of the cycle, of 10 women who became pregnant, the test gave a positive result 13.6 days (on the average) after the rise of the basal body temperature. Especially in acute gynaecological emergencies the test is of value, because of its sensitivity and practicability. PMID- 6922818 TI - Vasopressin and cardiovascular system in aging. AB - The studies concerned age-dependent peculiarities of the vasopressin effect on the hemodynamics and tone of the coronary vessels in dogs, the contraction of the isolated vascular strip in rats, and the hemodynamic and ECG indices in rabbits and in rats. The data obtained indicate the great sensitivity of old vessels to vasopressin. In aging, both humans and animals show a rise of vasopressin concentration in the blood. Age-dependent differences of the vasopressin effect on the kallikrein-kinin system, adenosine metabolism, the contents of prostaglandins and cyclic AMP have been established. High sensitivity to vasopressin in combination with its increased concentration in the blood is an important factor that contributes to the development of arterial hypertension and ischemic heart disease. PMID- 6922819 TI - Complement activation and complement control proteins in acute pancreatitis. AB - Serum levels of the complement proteins C3, C4, C1 inhibitor (C1 INH), factor I (C3b inactivator) and factor H (BIH) and plasma levels of cleavage products of C3 (C3c) and factor B were measured in 26 patients with acute pancreatitis. Breakdown of C3 occurred in 19 patients, as shown by a reduction in C3 level and the presence of C3c. C4 levels, however, did not fall and factor B breakdown products were not detected, thus suggesting that enzymatic cleavage of C3 occurred without significant involvement of either the early classical pathway or the alternative pathway. C1 INH and factor H both showed increases, presumably reflecting an acute phase response. Factor I showed an initial fall followed by a rise. There was no correlation between the presence or extent of C3 breakdown and the clinical condition of the patients. It is concluded that C3 cleavage in pancreatitis probably results from tryptic activity and that the measurement of complement components has no part to play in the management of the disease. PMID- 6922820 TI - Care of the acutely ill older adult. Facing death together. PMID- 6922822 TI - Care of the acutely ill older adult. Home safe. PMID- 6922821 TI - Care of the acutely ill older adult. Planning for discharge. PMID- 6922824 TI - Nutrition. Diet and digestive problems. PMID- 6922823 TI - Talking with Emma. PMID- 6922826 TI - The manuscript review process of nursing journals. PMID- 6922825 TI - Through a looking glass: life and health patterns in new China. PMID- 6922829 TI - What differentiates clinical research? PMID- 6922830 TI - Integrating Navajo tradition into maternal-child nursing. PMID- 6922827 TI - Networking and nursing. PMID- 6922828 TI - Attitudes toward the elderly among female college students. PMID- 6922832 TI - Laundry chute cleaning recommendations. PMID- 6922831 TI - Restriction of hospital employees with active HSV. PMID- 6922833 TI - Hepatitis B vaccine. PMID- 6922834 TI - Presumed autoclave failure due to false-positive spore strip tests. AB - The sterilizing processes in autoclaves and ethylene oxide sterilizers are challenged on a regular basis with a controlled inoculum of spores from two Bacillus species. Within a two-day period in March 1980, the seven autoclaves at this 550-bed hospital appeared to have failed in their function of killing spores on 18 out of 46 test strips. A shut-down of the autoclaves and a massive investigation failed to identify any mechanical, physical, or human failures. However, after 48 hours, it was found that the broth used as growth medium contained a contaminant, Bacillus coagulans, that resulted in broth turbidity at 55 degree C. Incubating an uninoculated tube of trypticase soy broth (TSB) for quality control at 55 degree C in addition to the usual 37 degree C quality check is a recommended safeguard against such occurrences. PMID- 6922835 TI - Recommended precautions for patients with Legionnaires' Disease. AB - As diagnostic techniques for the identification of Legionella species have become readily available, recognition of the pneumonic form of Legionellosis has increased. In particular, cases of hospital-acquired Legionella pneumophila are being identified and this has led to concern over possible person-to-person transmission. In most epidemiologic investigations where a source has been identified, water has been implicated. Person-to-person transmission has not been convincingly documented. Therefore, we discourage expensive or inconvenient special precautions for patients hospitalized with Legionnaires' Disease. Rather, we recommend that such patients be placed in secretion precautions until effective antimicrobial therapy has eradicated the organism. PMID- 6922836 TI - Post-basic nursing education in Zambia. PMID- 6922838 TI - Ask a stupid question... PMID- 6922837 TI - Ambiguity and paradox in outpost nursing. PMID- 6922839 TI - In-service education for nursing service administrators--bridging a gap? PMID- 6922841 TI - New trends in adoption. PMID- 6922840 TI - Childhood deaths in an inner city area, 1977-1979. PMID- 6922842 TI - New approaches in health visiting. 1: A critique of the neighbourhood study in health visitor training. PMID- 6922843 TI - My first 18 months as a health visitor. PMID- 6922847 TI - How the HVA centre in Northern Ireland helped train midwives in Brazil. PMID- 6922844 TI - Men who assault their wives--what can health visitors do to help? PMID- 6922845 TI - Counselling for health visitors. PMID- 6922846 TI - Understanding the Vietnamese in Britain. Part III: Health beliefs, birth and child care. PMID- 6922848 TI - Helen House--a hospice for children. PMID- 6922849 TI - President's message. Technicians in the intensive care unit. PMID- 6922850 TI - Automatic implantable defibrillator for the patient with recurrent refractory malignant ventricular arrhythmias: case report. AB - Clinically, the first line of treatment for patients experiencing potentially lethal arrhythmias includes antiarrhythmic medications and/or treatment of underlying causes such as ischemia or congestive heart failure. However, if the treatment is not successful in controlling the arrhythmia, the automatic implantable defibrillator is a viable alternative for the prevention of sudden death in these patients. The case report presents one example of how the automatic implantable defibrillator can supplement conventional medical therapy when success in suppressing recurrent arrhythmias cannot be obtained. This concept has been demonstrated in this 59-year-old woman who underwent several medication trials in an attempt to control her life-threatening arrhythmias. PMID- 6922852 TI - Physiologic aspects and clinical implications of wound healing. PMID- 6922851 TI - Metabolic encephalopathy: neurologic and psychiatric considerations. AB - The diagnosis in patients who have psychiatric or neurologic manifestations as the result of toxins of great variety is not particularly difficult and usually can be achieved with a discerning history and physical examination. The EEG is a useful but not a necessary adjunct. The most difficult of these patients to sort out etiologically are those brought into the hospital, without history, in a flaccid coma or wild delirium or with mild or subtle delirium. The dementias are the main differential diagnosis. The hallmarks of metabolic encephalopathy are reduced awareness and fluctuating attention with defects in orientatioN, interpretation, memory, retention, and recall and with hesitant and clumsy motor performance. Prompt treatment is necessary to preserve the integrity of the master organ, the brain. Delay in treatment may convert metabolic encephalopathy into permanent dementia. PMID- 6922853 TI - Congenital diaphragmatic hernia: a review. PMID- 6922854 TI - Nursing care of the patient with rabies. PMID- 6922855 TI - Endocarditis resulting from Kingella kingae, presenting initially as culture negative bacterial endocarditis. PMID- 6922856 TI - The effect of the intensive care nursing role on job satisfaction and turnover. PMID- 6922857 TI - Rational ethical judgments utilizing a decision-making tool. PMID- 6922858 TI - Visiting policies for patients with myocardial infarction: a national survey. PMID- 6922859 TI - Disappearance of electrocardiographic pattern of posterior wall myocardial infarction after an acute anteroseptal myocardial infarction. PMID- 6922860 TI - A complication commonly overlooked. AB - Acute pulmonary embolism is one of the most underdiagnosed of the serious acute diseases that face the clinician. It is estimated to be the third most common cause of death in the United States. There is an increasing incidence of pulmonary embolism because of the growing size of the older population, greater number of extensive surgical procedures, increasing use of oral contraceptives, and prolongation of life in patients with metastatic malignancy. Pulmonary embolism is considered to be one of the most common single causes of death in the acute care general hospital. It is therefore important to appreciate that pulmonary embolism is a preventable and treatable disease. PMID- 6922861 TI - A case of Q waves that "weren't". PMID- 6922862 TI - [Expulsion without strain: a natural way of bearing down in labor]. PMID- 6922863 TI - [Information from the PKU-section - report of activities 1981]. PMID- 6922864 TI - [A year in America]. PMID- 6922865 TI - [From our neighbors. But for poor prenatal and obstetric care: stillborns could be saved]. PMID- 6922867 TI - Concerns of the ET in the care of the elderly ostomate: a survey. PMID- 6922868 TI - Fistulas of the head and neck. PMID- 6922866 TI - Effect of elastase-induced emphysema on the force-generating ability of the diaphragm. AB - The effect of emphysema on the ability of the diaphragm to generate force was examined in costal diaphragm muscle strips from 10 Golden hamsters killed 18 mo after intratracheal injection of pancreatic elastase in a dose producing hyperinflation (mean total lung capacity [TLC] = 163% of control) and generalized panacinar emphysema. 13 saline-injected normal animals served as controls. The time course of isometric tension and the effect of alterations in muscle fiber and sarcomere length on the isometric tension (T) generated in response to tetanizing electrical stimuli (length-tension [L-T] relationship) were examined. Elastase administration caused an increase in diaphragm muscle thickness and reduction in the length of costal diaphragm muscle fibers measured in situ. Emphysema significantly increased the maximum tetanic tension as a result of hypertrophy. Maximal tension corrected for increases in muscle cross-sectional area (T/cm(2)), however, was the same in emphysematous (E) and control (C) animals. Emphysema also shifted the muscle fiber L-T curve of the diaphragm but not of a control muscle, the soleus, toward shorter lengths. In contrast to the effects of E on the diaphragm muscle fiber L-T curve, the sarcomere L-T curve was the same in E and C. Since the length at which tension was maximal correlated closely with sarcomere number (r = 0.94; P < 0.001) reduction in the number of sarcomeres in series in muscles from emphysematous animals appeared to explain the shift in the muscle fiber L-T curve. We conclude that in elastase-induced emphysema adaptive changes both in diaphragm cross-sectional area and sarcomere number augment the force-generating ability of the diaphragm. We speculate that changes in sarcomere number compensate for alterations in muscle fiber length resulting from chronic hyperinflation of the thorax, while diaphragmatic muscle hypertrophy represents a response to changes in respiratory load and/or diaphragm configuration (LaPlace relationship). PMID- 6922869 TI - Vaginal fistulas: one management method. PMID- 6922870 TI - Utilization of pastes in enterostomal therapy. PMID- 6922871 TI - The Kock continent urostomy. PMID- 6922874 TI - Development of the nursing process through action research. AB - Implementation of the nursing process in practical nursing can be achieved in accordance with the principles of action research. A pre-requisite of the action research is a knowledge of the basic principles and the component areas of the nursing process, and of the opportunities for applying the nursing process to practical work. The documentation of the nursing of the patient is one clear object in which the model of the nursing process takes concrete shape. Another prominent form of action is the analysis of the content of the nursing, and on the basis of this framework the needs of individual patients can be determined and evaluated. Important methods in action research are consulting and work guidance. The researcher, together with the workers, endeavours to develop the work of nursing and to seek opportunities and methods to carry out the nursing process model. PMID- 6922873 TI - The effect of care programmes on the dependency status of elderly residents in an extended care setting. AB - This paper presents data gathered in an operational research project undertaken in a geriatric centre providing care for approximately 400 long-term residents. The centre supplies nursing, medical, paramedical, day hospital and home care services. Programmes of social and diversional activities are provided and residents are also visited by various community groups. However, the long-term residents participating in this project represent a section of the population unable to utilize or participate in the social and diversional programmes usually offered. The aim of the study was to determine whether the dependency status of residents receiving long-term care is affected by nursing and/or medical patterns of institutional management. The project was carried out in two stages: 1 a habit training toileting programme intended to improve continent status; 2 activity programmes at differing levels of intensity and specifically designed to increase mental, social and physical stimulation. PMID- 6922872 TI - The continent ileal reservoir (Kock pouch): a new approach. PMID- 6922877 TI - Community nursing and civil liberty. PMID- 6922876 TI - "Tell it as it is'--qualitative methodology and nursing research: understanding the student nurse's world. AB - The aim of this paper is to demonstrate the utility of qualitative methods for nursing research, to this end a case is made for the use of fieldwork methods. The paper focuses upon a study which was concerned with student nurses' accounts of their experience of being learners of nursing. An overview of the students' construction of their nursing world is given and then the discussion moves to one particular aspect described as "nursing in the dark'. This is a conceptual category which deals with the data pertaining to the student's difficulties concerning what they could say to patients. The reader is thus furnished with a substantive as well as a methodological view of the study. The analysis draws upon the work of Glaser & Strauss, both in the attempt to generate ground theory and by reference to their work concerning awareness contexts. PMID- 6922875 TI - Developing effective management for the general nursing service. AB - Directors of nursing services and their colleagues in the new units created by NHS restructuring face major challenges in developing effective management for the general nursing service. Emerging ideas within the profession on the organization of nursing work, severe pressures arising from financial constraints at a time of growing health care needs, and restructuring itself each demand a carefully planned response. Beginning from the basic management cycle involved in implementing the nursing process, this paper offers a redefinition of the main functions of nursing management as a whole in meeting these challenges and provides a check-list for reviewing existing management practice. The use of this check-list is then illustrated by a case study in one health district. In this example, managers sought external assistance in planning a programme of action to strengthen nursing leadership. Similar efforts elsewhere are likely to rely mainly on a range of self-help methods. This paper is intended to provide a tool for designing and implementing these local strategies of management development. PMID- 6922878 TI - Ward sister--teacher or facilitator? An investigation into the behavioural characteristics of effective ward teachers. AB - The ward sister role is increasingly coming under study. This paper summarizes research into learning in the ward environment. The study being one of several on a similar theme, to have been published in the past 2 years. The research concentrated in particular on the behavioural characteristics of trained nurses perceived as good teachers. Attitudes and perceptions of teaching and learning were investigated by interviewing trained and trainee nurses. The data concerning good teachers collected at interviews were developed into a questionnaire and the results factor analysed. In the third phase of the study trained nurse-trainee verbal communications were observed and analysed to determine any relationship between verbal behaviours and effective teaching. The findings of the study led to the conclusion that on the job teaching of nurses is a complex global act in which the role model presented to the learner has a powerful influence while it could not be said conclusively that a link between effective teaching and verbal behaviour was identified, a trend towards a more participative mode of communication was noted in two identified good teachers. PMID- 6922879 TI - Career paths of graduates of a degree-linked nursing course. AB - The aim of this study was to follow the career development of all 103 former students of the BSc (Hons) degree in human biology at the University of Surrey who also took the nursing option leading to qualification as SRN, at St George's School of Nursing, London. These individuals qualified between 1970 and 1980. A postal questionnaire was used and a 97% response was obtained. The employment of each respondent was recorded at various time intervals after qualification and categorized to facilitate analysis. Findings were generally in accordance with the preliminary findings of the Universities of Manchester and Edinburgh follow up studies. The majority of respondents chose and followed careers in nursing. The most common categories of employment for the first 5 years after qualification were hospital and community nursing. Sixty-two percent had taken further training in various fields of nursing. A larger proportion of human biologist nurse graduates had selected careers in community nursing, nursing research and nursing education than had Edinburgh nurse graduates. There was support for the suggestion that nurse graduates choose to consolidate their experience before breaking their career on account of motherhood. Between 9 and 31% were in non-nursing employment during the first 5 years of employment. Most of these were studying or working in health related fields. This figure was higher than that found in Edinburgh and reflects the nature of the degree-linked human biology/nursing option course. PMID- 6922881 TI - The Euro-nurse: theory or reality. PMID- 6922880 TI - Universities and nursing education. AB - Trends reflected by Department of Health and Social Security statistics on the nursing workforce are examined and the ratios between grades discussed. Recruitment into nursing degree courses in the UK is considered in relation to overall recruitment into nursing. The somewhat ambiguous position of nursing degree courses in the UK leads into consideration of policy statements by the universities and the nursing profession. The importance of such policies is emphasized in the current financial climate, as are the potential contributions of university departments to professional debate, for example standards of care. Comparisons are drawn between the goals of courses involving full-time studentships as opposed to part-time apprenticeships and the present boundaries between these noted, especially in relation to the expanding roles of courses. On going research into the preparation of nurse-tutors in the UK is mentioned, together with a preliminary analysis of the academic basis in the biological sciences possessed by learners and tutors. Out of this is derived a suggestion that the present-day shortage of nurse teachers could be helped by varying the existing patterns of recruitment, especially involving subject specialists in the biological, behavioural and social sciences. PMID- 6922882 TI - Effects of iodipamide on human C3 and factor B in vitro. AB - The effects of iodipamide on C3 and factor B in normal human serum and in purified form have been examined by immunoelectrophoresis and sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). Temperature-dependent changes in immunoelectrophoretic profiles have been observed; however, these are not the same as those obtained after treatment of normal human serum (NHS) with cobra venom factor Naja naja. Analyses of iodipamide-treated NHS and purified C3 and factor B by reducing SDS-PAGE indicate that no macromolecular changes have occurred in C3 and factor B that can be ascribed to proteolysis (i.e., activation). The changes observed in C3 and factor B, including loss of hemolytic activity, appear to be due to direct interactions between iodipamide and C3 and factor B. In the case of factor B, iodipamide treatment at 37 degrees C induces aggregation, which is reversible upon reduction with beta-mercaptoethanol. PMID- 6922885 TI - Overcoming ageism in long-term care: a solution in group therapy. PMID- 6922883 TI - The reshaping of the old. PMID- 6922884 TI - Health care professionals vs. the elderly. PMID- 6922886 TI - What is it about the elderly that elicits a negative response? PMID- 6922887 TI - Does your behaviour affect your patient's response? PMID- 6922888 TI - The need for gerontologic content within nursing curricula and other conclusions based on a recent survey. PMID- 6922889 TI - More on getting and keeping good nurses. PMID- 6922890 TI - Motivating staff: a look at assumptions. AB - Motivational theory can be a helpful tool to enrich staff's jobs. Some of the literature seems to promise that if we master certain formulas or learn certain procedures we can motivate employees to incredible levels of performance. This discussion lays to rest such expectations. Reviewing the concept of work motivation and pointing out the useful elements that are at the heart of the various motivational theories, the author seeks to make sense of the diversity and seeming contradictions among the theories. The discussion is directed specifically to nursing home administrators; however, the author's perspective can be used by all nursing administrators to integrate theory with the real world situation to provide a motivating environment for staff. PMID- 6922891 TI - Staffing statistics: their use and usefulness. PMID- 6922892 TI - Collaboration benefits nursing service and education. PMID- 6922893 TI - Nurse discontent: the search for realistic solutions. PMID- 6922896 TI - Cancer quackery--what to watch out for. PMID- 6922894 TI - Nursing care of the cancer patient and family as a unit. PMID- 6922895 TI - You and your health. When enough is enough: the problems of stress and burnout. PMID- 6922897 TI - Dealing with the cancer patient and his pain. PMID- 6922898 TI - Problems in wound healing. PMID- 6922899 TI - Reconstructive breast surgery: a 3-minute report for nurses. PMID- 6922900 TI - Professional judgment - another dimension. PMID- 6922901 TI - Common misconceptions regarding exercise. PMID- 6922902 TI - Nursing assessment of rhytidectomy patients--the use of Roy's model. PMID- 6922904 TI - Will the next few years see more or less plastic surgery? PMID- 6922905 TI - Temporary topical chemical prosthesis. PMID- 6922908 TI - Hypertension: an overview. PMID- 6922903 TI - Anticipate the unforeseen: cardiac arrest. PMID- 6922906 TI - Traveling abroad. PMID- 6922909 TI - Diet - a way of life. PMID- 6922907 TI - Patient care tips: over-the bed hoist from standard traction equipment. PMID- 6922910 TI - The basics of medical photography in plastic surgery. PMID- 6922911 TI - The role of the nurse in microsurgical procedures. PMID- 6922912 TI - The process of changing behavior through assertiveness training. PMID- 6922913 TI - "The weakest link". PMID- 6922917 TI - Needed: plastic surgery participation in public safety. PMID- 6922916 TI - Diets for patients with wired jaws. PMID- 6922914 TI - Evaluation of the injured hand. PMID- 6922915 TI - Injuries in downhill & cross country skiing. PMID- 6922918 TI - Maxillofacial injuries. PMID- 6922919 TI - Measurements in plastic surgery: cosmetic surgery of the face. PMID- 6922920 TI - II. Measurements in plastic surgery: breast surgery. PMID- 6922923 TI - Psychological aspects of microsurgical replantation. PMID- 6922921 TI - Warning: sun tanning may be hazardous to your health. PMID- 6922924 TI - "The expanding role of the O.R. nurse". PMID- 6922925 TI - Ask a lawyer. PMID- 6922922 TI - Systemic lupus erythematosus. PMID- 6922926 TI - Family theory and family therapy models: comparative review with implications for nursing practice. AB - Although theories of the family and theories of family therapy have different origins and purposes, both provide the basis for a family focused nursing approach. Family theory is a practice theory with a focus on health while family therapy is a practice theory with a focus on pathology. Thus, the contributions of each are different. For nurses to adapt and apply the principles of the two theories correctly, they first must understand whether application of a basic theory with a focus on health or a practice theory with a focus on pathology is appropriate in the particular nursing situation. For example, if a husband is hospitalized, recovering from a myocardial infarction, a family focused nursing approach is mandatory in providing optimal nursing care. Assessment of the family situation will provide clues for the functional or dysfunctional state of the family and the appropriateness of utilizing family theory or family therapy principles. If the current state of family relationships is optimal, application of family theory principles than can be applied to guide health promotion on a family level is appropriate. Organizational and dynamic aspects of the family promoting the husband's recovery can be accentuated, supported, and emphasized in the nursing care. However, if the current state of family relationships is pathological, application of family therapy principles is appropriate. Here the goal of the nursing care is restoration of functional organizational patterns and interactive processes between family members. PMID- 6922927 TI - Identity operations and family treatment. PMID- 6922928 TI - Wives of alcoholics: the "forgotten patients". PMID- 6922929 TI - Role-modeling the extended family: fostering autonomy in C.S.S. acute day hospital clients. PMID- 6922930 TI - Observations of Syrian hamster fetuses after exposure to 2450-MHz microwaves. AB - The teratogenic potential of microwaves was examined in a rodent species, the Syrian hamster. Exposure of hamsters to 2450-MHz CW microwaves at a power density of 20 mW/cm2 (estimated SAR = 6 mW/g) for 100 minutes daily on days 6-14 of gestation caused no significant change in fetal survival, body weight, skeletal maturity, or incidence of terata. Thirty mW/cm2 (estimated SAR = 9 mW/g) caused significantly increased fetal resorptions, decreased fetal body weight, and decreased skeletal maturity. Rectal temperatures of pregnant hamsters after exposure to 20 mW/cm2 were slightly increased (0.4 degrees C) over those of sham irradiated dams; 30 mW/cm2 caused maternal rectal temperatures to be increased 1.6 degrees C over sham-irradiated dams' temperatures. It appears that the hamster fetus may be more susceptible to microwave radiation than the mouse. PMID- 6922931 TI - Assessment of immune function development in mice irradiated in utero with 2450 MHz microwaves. AB - Groups of time-bred pregnant mice were irradiated with 2450-MHz microwaves at an incident power density of 28 mW/cm2 for 100 min daily from day 6 to day 18 of pregnancy. The average specific absorption rate (SAR) was 16.5 W/kg. Two experiments were performed under these conditions. At 3 and 6 weeks of age the mice were assessed for development of the primary immune response to sheep erythrocytes, in vitro mitogen-stimulated lymphocyte proliferation, and natural killer (NK) cell activity. No consistent significant difference in the primary immune response, in the mitogen response, or in the NK cell activity was observed between irradiated and sham-irradiated mice. PMID- 6922932 TI - Effects of ambient temperature and exposure to 2450-MHz microwave radiation on evaporative heat loss in the mouse. AB - Whole-body evaporative heat loss was measured as whole-body evaporative water loss in mice during a 90-min exposure to 2450-MHz microwave radiation at an ambient temperature of 20 degrees C and in non-exposed mice maintained at ambient temperatures of 20, 25, 30, 33, and 35 degrees C. The ambient-temperature threshold for increasing evaporative water loss was between 30 and 33 degrees C. A specific absorption rate of microwave radiation in excess of 29 W/kg was required to produce an increase in heat loss. For absorption rates ranging from 29 to 44 W/kg, the mouse dissipated 65% of the total absorbed heat by water evaporation; the remainder was dissipated passively. The data collected in the mouse may be extrapolated to larger species, such as man, but only by an exponential relationship. Using this relationship, it was shown that a threshold specific absorption rate of 29 W/kg in a 0.033-kg mouse was equivalent to approximately 0.25 W/kg in a 70-kg human. PMID- 6922933 TI - Microwave thermography--characteristics of waveguide applicators and signatures of thermal structures. AB - In this paper, we study the problem of the interpretation of the signals provided by microwave thermography, which allows the detection of the thermal gradients in living tissues. These signals correspond to the thermal noise measured by a radiometer when the probe scans the surface of the tissues (passive process). We describe how these signals can be computed by means of a new method based on the antenna reciprocity principle. This process requires a knowledge of the electrical field distribution in the lossy medium when the applicator is radiating a microwave signal (active process). Examples of computations of the thermal signals and experimental verifications are presented. Then, we introduce a new concept of 'thermal signature' and show how it is possible to reach a quantitative interpretation of the thermal signals such as those obtained in clinical investigations (thermal pattern recognition). PMID- 6922934 TI - Problems in evaluating cardiac protein synthesis. PMID- 6922935 TI - Identifying diabetics at high risk for vision loss. PMID- 6922937 TI - Diabetes mellitus: classification, etiology, diagnosis, complications, and possible ocular manifestations. PMID- 6922938 TI - Perspective on contact lenses. PMID- 6922936 TI - Taking a genetic family history. PMID- 6922939 TI - Nursing rounds. PMID- 6922941 TI - Topical ophthalmic anesthetics. PMID- 6922940 TI - Joint Commission on Allied Health Personnel in Ophthalmology pursued the public interest. PMID- 6922942 TI - What's your impression? PMID- 6922943 TI - Screening for diabetic retinopathy in a diabetic management clinic. PMID- 6922944 TI - Penicillin gets some help against resistant pathogens. PMID- 6922947 TI - [Fujimori's method of breast care]. PMID- 6922948 TI - [Activities of midwives assigned by hospitals to new mothers and infants after discharge--a follow-up observation of infant nutrition from the time fo discharge to the third-month checkup]. PMID- 6922946 TI - [Clinical evaluation of amoxicillin sustained-release preparation in urinary tract infection]. AB - C-AMOX, a new prolonged acting preparation of amoxicillin was administered to 122 cases by oral administration of daily dosage 500 mg twice. Clinical effectiveness of C-AMOX was evaluated in 115 out of 122 cases (acute simple cystitis 87 cases, acute pyelonephritis 6 cases, complicated urinary tract infection 19 cases and others 3 cases), and the following results were obtained. 1. The clinical effect for 87 cases of acute simple cystitis was excellent in 54 cases (62%), moderate in 24 cases (27.6%) and poor 9 cases (10.3%), overall effective rate being 89.7%. 2. The clinical effect for 19 cases of complicated urinary tract infection was excellent in 6 cases (31.6%), good 8 cases (42.1%) and poor 5 cases (26.3%), overall effective rate being 73.7%. 3. Adverse reaction occurred in 2 patients, one gastric discomfort and the other one slight diarrhoea. No laboratory abnormalities attributable to C-AMOX were observed in the present study. PMID- 6922949 TI - [My future problems in learning Okaya's method of breast massage]. PMID- 6922945 TI - [Bacteriological evaluation of netilmicin]. AB - The following results were obtained from the bacteriological evaluations of netilmicin (NTL), a newly developed antibiotic agent, with gentamicin (GM), dibekacin (DKB) and amikacin (AMK) as the controls. (1) NTL demonstrated broad antibacterial spectra against both Gram-positive and Gram-negative bacteria, but its antibacterial potency against streptococci was not very strong among other Gram-positive bacteria. (2) In terms of distribution of sensitivity of clinically isolated bacterial strains, NTL proved to have antibacterial potency comparable to that of GM and higher potency than that of DKB of AMK against E. coli K. pneumonia, Enterobacter sp., or H. influenzae. However, its efficacy was inferior to GM against Proteus sp., S. marcescens and P. aeruginosa. (3) In conjunction with the influences of pH of culture media or of addition of horse sera upon the antibacterial efficacy, NTL showed an inclination similar to that of GM, DKB and AKM. Its antibacterial efficacy was fortified on the alkaline side or by addition of sera. In connection with the influences of the amounts of inoculated bacteria upon antibacterial efficacy, there were hardly any appreciable influences on it by any of the tested bacterial strains. (4) The interactions of NTL with carbenicillin were evaluated with the chequerboard titration method to find remarkable cooperative actions in any of E. coli, K. pneumoniae, S. marcescens, A. calcoaceticus and P. aeruginosa. (5) The results of evaluation on the patterns of its antibacterial effects revealed that it acted bactericidal in any tested bacterial strains. (6) As to the therapeutic effects against experimental infections in mice, it was found out that NTL = GM greater than DKB and AMK against E. coli, GM greater than NTL = DKB and AMK against K. pneumoniae and GM and DKB greater than NTL greater than or equal to AMK against A. calcoaceticus and P. aeruginosa in the decreasing order of efficacy. PMID- 6922951 TI - [Research on breast feeding in Japan]. PMID- 6922950 TI - [Status of breast feeding and the efforts at our hospital for its promotion]. PMID- 6922952 TI - [Experience in nursing assistance in breast feeding: an experience at the ambulatory service for breast feeding at Nagoya Seirei Hospital]. PMID- 6922953 TI - [Report on the first professional midwifery meeting--an interview with Ms. Aoki, past director]. PMID- 6922954 TI - [The past and present of customs concerning childbirth. 8. Clothes for the newborn infant]. PMID- 6922955 TI - [The quiet revolution]. PMID- 6922956 TI - [Sampling methods]. PMID- 6922957 TI - [Death of a patient at home: home nursing of terminal cancer patients living alone]. PMID- 6922958 TI - [Problems involving the patients in the terminal stage of cancer and being cared for at home by the visiting nurse]. PMID- 6922959 TI - [Home nursing of a patient with cerebral infarction who was discharged while in an acute condition]. PMID- 6922960 TI - [Possibilities and limitations of home nursing of patients in the terminal stage of cancer. A discussion]. PMID- 6922962 TI - [Bedside nursing. Nursing to assist an aged bedridden patient at home to regain a locomotive function: team care by the staff of a clinic]. PMID- 6922961 TI - [Bedside nursing. Teamwork for speech therapy of an aphasic patient: on the role of the nurse]. PMID- 6922963 TI - [Bedside nursing. Nursing of a patient with terminal skin cancer who was aware of his clinical condition]. PMID- 6922964 TI - [A lesson in geriatric nursing: development of a trusting relationship]. PMID- 6922965 TI - [Ambulatory nursing conference. 5. At Life Planning Center Clinic. Care of a patient with abnormal fear of flatulence: documentation of problem list for POS and its application in guidance of the patient]. PMID- 6922967 TI - [Physiology and health effects of smoking. 12. Smoking and women (3): the effects of smoking on perinatal mortality]. PMID- 6922966 TI - [Clinical aspect of adolescence. 3. Psychological characteristics of adolescence. 2]. PMID- 6922968 TI - [Oral (dental) diseases: questions and answers. 4. Orthodontics]. PMID- 6922969 TI - [Transactional analysis. 14. Transactional analysis in terminal care. (1)]. PMID- 6922971 TI - [Aging report. Geriatric care in England. 7. Geriatric departments at Hull and Birmingham]. PMID- 6922972 TI - [Unforgettable life in Malawi. 7]. PMID- 6922973 TI - [Various phases of apprehension]. PMID- 6922970 TI - [Profile of a nurse. Mr. Mitsugi Hoshino who has been involved in hemodialysis nursing from the start]. PMID- 6922974 TI - [Understanding anger]. PMID- 6922975 TI - [Nursing of a patient who expresses distrust of the physician: easing of apprehension of a patient with esophageal cancer]. PMID- 6922976 TI - [Various phases of apprehension of patients at a psychiatric hospital]. PMID- 6922979 TI - [Bedside nursing: assistance of a child with severe affective disturbance. Re establishment of verbal communication]. PMID- 6922978 TI - [Nursing of a patient with lethal midline granuloma who expressed anxiety and fear of death]. PMID- 6922977 TI - [Support of a patient with depression due to sudden transfer to an isolation ward]. PMID- 6922980 TI - [Bedside nursing. An approach to a patient in the terminal stage of cancer. 2. Encouragement of the patient in developing a positive attitude toward therapy]. PMID- 6922981 TI - [Bedside nursing. Temporary discharge of a hemiplegic patient to test her adaptation to the home environment: prevention of regression of ADL at home]. PMID- 6922983 TI - [Bedside nursing: care of a patient with few complaints in spite of pain caused by cancer. Understanding of the patient using Ego-gram]. PMID- 6922984 TI - [The role of the nurse in cardiac rehabilitation in the United States]. PMID- 6922982 TI - [Assistance in the care of oral pain of a patient with a hematologic disease]. PMID- 6922986 TI - [Clinical aspects of adolescence. 4. Characteristics of psychopathology. 1]. PMID- 6922987 TI - [Physiology and medical significance of smoking. 13. Smoking and women (4): delayed effects on the fetus]. PMID- 6922985 TI - [Ambulatory nursing conference. 6. A the Life Planning Center Clinic. Approach to a diabetic patient: persuasion of a patient mistrusting chemotherapy]. PMID- 6922988 TI - [Transactional analysis in nursing. 15. Transactional analysis used in terminal care]. PMID- 6922989 TI - [Profile of a nurse. Ms. Toshiko Ibe, one of the first graduates of St. Luke's Graduate School of Nursing]. PMID- 6922990 TI - [Aging report: geriatric care in England. 8. Geriatric care in various areas. 4. Nottingham and Manchester]. PMID- 6922991 TI - [Unforgettable life in Malawi. 8. Anemia, malnutrition, and malaria]. PMID- 6922993 TI - [Medicine, diet, and farming. Medical care directly tied to the earth: combining medicine, food habits and farming for better health]. PMID- 6922994 TI - [Study on the knowledge of diabetic patients and the extent of their disease control]. PMID- 6922992 TI - [Attitudes and behaviors related to radiation exposure]. PMID- 6922995 TI - [Ambulatory nursing conference. 7. At the Life Planning Center Clinic. Patient's description of hypertension based on self determination of blood pressure: effective method of communication with patients]. PMID- 6922996 TI - [Clinical characteristics of adolescence. 5. Characteristics of adolescent psychiatry. 2]. PMID- 6922997 TI - [Physiology and hygiene related to smoking. 14. Physiological effects of passive smoking. (1): on acute effects]. PMID- 6922999 TI - [Transactional analysis used in nursing. 16. Transactional analysis in terminal care]. PMID- 6922998 TI - [Oral (dental) diseases: questions and answers. 6. Periodontal diseases]. PMID- 6923001 TI - [Aging report: geriatric care in England. 6. At Manchester and Leeds]. PMID- 6923000 TI - [Profile of a nurse. Ms. Teruko Hirakue, a 40-year-old nursing student]. PMID- 6923002 TI - [Unforgettable life in Malawi. 9. Health education]. PMID- 6923003 TI - [Information on radiation exposure: questions and answers]. PMID- 6923004 TI - [Pathology of malignant lymphoma]. PMID- 6923005 TI - [Clinical features and diagnosis of malignant lymphoma]. PMID- 6923006 TI - [Therapy of malignant lymphoma and related problems]. PMID- 6923007 TI - [Complications of malignant lymphoma and their management]. PMID- 6923008 TI - [Nursing assessment and nursing keypoints at admission of patients with malignant lymphoma]. PMID- 6923009 TI - [Nursing involved in various tests for malignant lymphoma--observation in 2 cases]. PMID- 6923010 TI - [Nursing of patients with malignant lymphoma. Prolongation of treatment and mental and physical stability--on the role of nursing]. PMID- 6923011 TI - [Nursing of patients with malignant lymphoma. Adverse effects of antineoplastic agents and nursing care]. PMID- 6923012 TI - [Nursing of a patient with malignant lymphoma with various complaints--a case study and reaffirmation of the importance of sensitivity of nursing personnel]. PMID- 6923013 TI - [Psychological approach to a patient with malignant lymphoma who was re-admitted following remission (and recurrence)]. PMID- 6923014 TI - [Terminal care of patients with malignant lymphoma]. PMID- 6923015 TI - [Nursing of patients with malignant lymphoma. Conference. An apprehensive patient with poor prognosis]. PMID- 6923016 TI - [Survey on food intake by patients in the field of internal medicine--nutritional intake and patients' understanding of the diet]. PMID- 6923018 TI - [Significance and practice of nursing diagnosis in the ambulatory dermatological service]. PMID- 6923017 TI - [Nursing diagnosis. Diagnosis of the skin (II). Observation of the skin (2)]. PMID- 6923019 TI - [Communication by patients with amyotrophic lateral sclerosis and innovation in nursing call devices]. PMID- 6923021 TI - [Capacity for self control by diabetic patients and its relationship to nursing (II)--care of diabetic outpatients at Hyogo Medical College Hospital]. PMID- 6923020 TI - [Nursing diagnosis: looking at its use in the clinical area]. PMID- 6923022 TI - [Rehabilitation nursing and activities of daily living of patients with acute myocardial infarction (1)--problems in nursing, significance of PRP (pressure rateproduct), and its application to the work of toothbrushing]. PMID- 6923023 TI - [Research in nursing education--analysis of the studies conducted during the past 5 years (1977-1981)]. PMID- 6923024 TI - [Research in nursing education. On teaching methodology in nursing education: a discussion]. PMID- 6923025 TI - [Research in nursing education. Problems in clinical training in psychiatric nursing: a questionnaire on problems faced by nursing students]. PMID- 6923026 TI - [Factors related to nursing students' attitudes and nursing behaviors to terminal patients]. PMID- 6923027 TI - [Nursing process, student attributes and teaching methodologies]. PMID- 6923029 TI - [Application of transactional analysis in clinical training of adult nursing - for effective interpersonal relationship between nursing students and patients in clinical training]. PMID- 6923028 TI - [Process leading to formulation of a nursing research design--with special reference to an approach to experimental studies]. PMID- 6923030 TI - [Anxiety associated with clinical training in basic nursing]. PMID- 6923031 TI - [Interactions with students in clinical training: training in adult nursing in neurosurgery]. PMID- 6923032 TI - [On the "roots" of St. Christopher Hospice: search for the background of the modern hospice movement. (2)]. PMID- 6923033 TI - [On nursing education: nursing and nursing study. 3]. PMID- 6923034 TI - [In search of humane education. (9). The theory of teaching. 4]. PMID- 6923035 TI - [Re-evaluation of public health nursing activities, with special reference to the regional care of patients with refractory diseases: report on the results of a study by public health nurses of the Tama area, Tokyo]. PMID- 6923036 TI - [Re-evaluation of activities in the care of patients with refractory diseases in the Tanashi area]. PMID- 6923037 TI - [Structure of the regional care of refractory diseases at Higashi-Murayama-Shi and re-evaluation of the process of its development]. PMID- 6923038 TI - [Re-evaluation of regional care of refractory diseases at Hino-Shi]. PMID- 6923039 TI - [Re-evaluation of public health nursing activities and application of the results to practice: observation and suggestions based on the re-evaluation]. PMID- 6923040 TI - [Comprehensive re-evaluation of public health nursing activities: through the process of studying analytic methods]. PMID- 6923041 TI - [Assistance of a family incapable of financial independence and residing in special public housing. (I)]. PMID- 6923043 TI - [NHS in Scotland and Denmark (11). Meal service in Copenhagen]. PMID- 6923042 TI - [Importance of the public health nurse acting on her belief]. PMID- 6923044 TI - [National public health nursing activities in Gunma Prefecture reflected in a personal history: public health nursing incorporated into the government's military health policy]. PMID- 6923045 TI - [Practice of home nursing technics. 18. Care involved in excretion. (4)]. PMID- 6923047 TI - [An important decision]. PMID- 6923046 TI - [Approach to implementation of primary health care legislation (1). Result of a survey on cooperation between physicians and public health nurses - an example at Matsudo-Shi]. PMID- 6923048 TI - [Breast cancer today - a survey]. PMID- 6923049 TI - [The family in the Soviet Union: population development must be promoted]. PMID- 6923050 TI - [First graduates from a midwifery course in camp Ban Vinai refugee camp on 20 March 1982]. PMID- 6923051 TI - [Midwives' opinion on abortion]. PMID- 6923052 TI - [Abortion, a right or a crime?]. PMID- 6923053 TI - [Is it possible to avoid eyelid swelling in the neonate by changing the routine of Crede prophylaxis?]. PMID- 6923054 TI - [Getting acquainted with nursing practices in Karolinska Hospital]. PMID- 6923055 TI - [New guidelines on counseling in family planning]. PMID- 6923056 TI - [Episiotomy--yes or no?]. PMID- 6923057 TI - [Obstetricians get ready to discuss: episiotomy, an unnecessary practice?]. PMID- 6923060 TI - [A Finnish midwife in Bangladesh]. PMID- 6923059 TI - [Study trip to Pithivier's maternity hospital]. PMID- 6923058 TI - [Alcohol and the unborn child]. PMID- 6923061 TI - [Study on air circulation in paper and cloth diapers: a comparison of temperature and humidity inside the diapers in summer]. PMID- 6923062 TI - [The effects of heat and air-conditioning on the patient]. PMID- 6923063 TI - [Living environment of the hospital in summer]. PMID- 6923064 TI - [Summer and school nurses: a summer camp with emphasis on mountain-climbing and the school nurse]. PMID- 6923065 TI - [Home visiting by nurses in summer: concerns of public health nurses]. PMID- 6923067 TI - [Current status and overview of continued nursing]. PMID- 6923066 TI - [Communication patterns and the effects of information transmission in health education]. PMID- 6923068 TI - [Role of the infection control nurse in surveillance, prevention, and control of hospital-associated infections. A report on the International Conference on the Infection Control Nurse in the Surveillance, Prevention and Control of Hospital Associated Infections held at Copenhagen from Nov. 6th to 10th, 1978]. PMID- 6923070 TI - [Profile. Ms. Mitsuko Kurebayashi who participates in a new form of regional health care and continues in home care]. PMID- 6923071 TI - [Medical episode: bronze baby syndrome]. PMID- 6923072 TI - [Medical episode: laughter and incontinence]. PMID- 6923073 TI - [Visit to New Guinea by a former military nurse after 38 years]. PMID- 6923069 TI - [Fulfilled mothers and babies. A report by a clinical nurse engaged in infant care. 4]. PMID- 6923074 TI - [Statistical file. Statistics at the time of establishment of public health nursing schools (1951)]. PMID- 6923075 TI - [Systematic nursing. 2. Nursing process to be applied to clinical scenes]. PMID- 6923076 TI - Maintaining your own health. Survey results. PMID- 6923080 TI - [Foreign patients in the hospital]. PMID- 6923077 TI - New dimensions in nursing education at Kansas Newman College. PMID- 6923079 TI - [Plasma kallikrein-kinin system of patients with embolisms of the arteries of the extremities]. PMID- 6923078 TI - [Changes in several indices of the blood kinin system and hemodynamics in patients with rheumatic heart defects]. PMID- 6923081 TI - [Infantile hypertrophic pyloric stenosis]. PMID- 6923082 TI - [Anaerobic infections]. PMID- 6923083 TI - [What value has thermography in diagnosis?]. PMID- 6923084 TI - [What is to be done when the bile overflows?]. PMID- 6923086 TI - [Ambulatory childbirth]. PMID- 6923085 TI - [Obligation of nursing students in the employment scheme, Letter of the Federal Committee of the study group of district nurse instructors]. PMID- 6923087 TI - [Rape, Initial experience report in emergency calls for women who are raped]. PMID- 6923088 TI - [The healthy and the diseased nail]. PMID- 6923089 TI - [Causes and therapy of chronic pyelonephritis]. PMID- 6923090 TI - Sexism in the school: a hindrance to health. PMID- 6923092 TI - The use of community health aides in a school health program. PMID- 6923091 TI - Pediatric residents as health educators: the reactions of children. PMID- 6923093 TI - School nurses and powerlessness. PMID- 6923094 TI - Self-concept development. PMID- 6923095 TI - School emergencies--preparation not panic. PMID- 6923097 TI - National survey of school nurse certification re-visited. PMID- 6923096 TI - Administration of medications during school hours. PMID- 6923099 TI - [Functions and roles of society and specialty journals in academic research]. PMID- 6923098 TI - [Information transmission in nursing research. Discussion]. PMID- 6923100 TI - [Nursing research and the role of periodicals related to nursing]. PMID- 6923101 TI - [Roles of the referee system in scientific journals]. PMID- 6923102 TI - [Nursing journal editors]. PMID- 6923103 TI - [Disseminating the results of nursing research]. PMID- 6923104 TI - [Focal point of nurses' attention on patients' families and nursing intervention in clinical setting. (3)]. PMID- 6923105 TI - [Man: a new clinical image (9). Psychodrama and psychosomatic medicine. (1)]. PMID- 6923106 TI - [Incorporation of the concept of primary nursing in the nursing process--on an effective method of in-service training]. PMID- 6923107 TI - [Progress in the studies of patient classification. (2)]. PMID- 6923109 TI - [Course planning and instruction in clinical training in adult nursing (1). The objectives and teaching methods in clinical training of adult nursing]. PMID- 6923110 TI - [New trend in allied health science education--on competency-based education]. PMID- 6923108 TI - [On the future of the system of nursing education in Japan]. PMID- 6923111 TI - [A trial in clinical training in adult nursing (2) A follow-up study and observation on the effects of training in 6 categories]. PMID- 6923112 TI - [Nursing education and regional mental health care in Hawaii (5). Regional mental health care in Hawaii (2)--the function of the Waikiki Mental Health Clinic. Interview by M Kawano]. PMID- 6923113 TI - [In search of a new nursing philosophy. XXIII. Illness: the presence of a nurse and its implication]. PMID- 6923114 TI - [Aging and the need for exercise]. PMID- 6923115 TI - [Nursing process: nursing of patients with hyperthyroidism. Physiopathology of hyperthyroidism]. PMID- 6923116 TI - [Nursing process: nursing of patients with hyperthyroidism. Diagnosis and treatment of hyperthyroidism]. PMID- 6923118 TI - [Nursing process: nursing of patients with hyperthyroidism. Nursing of a patient with hyperthyroidism: a case study]. PMID- 6923119 TI - [Nursing process: nursing of patients with hyperthyroidism. Evaluation of the nursing process: a discussion]. PMID- 6923117 TI - [Nursing process: nursing of patients with hyperthyroidism. Nursing process of patients with hyperthyroidism]. PMID- 6923121 TI - [The nursing process: possibilities and limitations of its planned implementation (10). Evaluation of procedures involved in each process: practice and evaluation methods of practice and objectives of the evaluation]. PMID- 6923120 TI - [Bedside tests: keypoints in nursing and interpretation of the data. Endocrine and metabolic function tests (1): Pituitary and thyroid function]. PMID- 6923122 TI - [Nursing actions with consideration to the patient's dignity - assistance in excretion by a patient who was aware of her terminal condition]. PMID- 6923123 TI - [Experiences with patients' attitudes to life and death]. PMID- 6923124 TI - [Surgery - basis and practice of care. Limb amputation: methods and keypoints in the care]. PMID- 6923125 TI - [Surgery - basis and practice of care. Limb amputation. Nursing of a patient undergoing leg amputation due to diabetic gangrene]. PMID- 6923127 TI - Allied health professionals and hospital privileges: an introduction to the issues. PMID- 6923126 TI - A procrustean approach to informed consent: the Texas Medical Disclosure Panel. PMID- 6923128 TI - Ethical dilemmas and the practice of infection control. PMID- 6923129 TI - Documentation of patient care: an often underestimated responsibility. PMID- 6923130 TI - Salute to hospital staff nurses: commitment, diversity, satisfaction. PMID- 6923131 TI - Financial aid for R.N. students. PMID- 6923132 TI - Why don't women attend for antenatal care? PMID- 6923133 TI - Why don't women attend for antenatal care? Is that all...? PMID- 6923135 TI - Anatomy of an ad campaign. PMID- 6923134 TI - College recruiting - a business proposition. PMID- 6923137 TI - Impaired nuclear transport of a human variant tRNAiMet. PMID- 6923136 TI - The challenge: providing quality health care available to all. Hospitals and economic perspectives. PMID- 6923138 TI - Cost-of-illness methodology: a guide to current practices and procedures. PMID- 6923139 TI - Ethical principles in nursing education and practice: a missing link in the unification issue. PMID- 6923140 TI - Second-step education for RN's. The quiet revolution. PMID- 6923141 TI - The use of the Rines model in differentiating professional and technical nursing practice. PMID- 6923142 TI - A study of nurses' attitudes toward the BSN requirement. PMID- 6923143 TI - Interinstitutional nursing programs: problem or solution? PMID- 6923144 TI - Nurses and pharmacists: a study of consultation patterns on patient units. PMID- 6923145 TI - An open letter to my educators. PMID- 6923146 TI - Educational preparation for nursing--1981. PMID- 6923148 TI - The nurse manager as leader. PMID- 6923149 TI - Are pre-retirement courses worth-while? PMID- 6923147 TI - Teamwork in nurse education - new ideas from Scotland. PMID- 6923150 TI - The coronary care unit - 1. The management of clinical specialties - 7. PMID- 6923152 TI - Psychiatric care American style. PMID- 6923153 TI - Analyzing accounting reports. PMID- 6923151 TI - Special risk patients: the legal problems. PMID- 6923154 TI - Determining cost of nursing services. PMID- 6923155 TI - Interviewing & selecting staff. PMID- 6923157 TI - Perceived stress & situational supports. PMID- 6923156 TI - The support group: a method of stress management. PMID- 6923159 TI - Supplemental staffing agencies: friend ... or foe? PMID- 6923158 TI - 90 days: a patient shares his perspectives, his humor and his thanks. PMID- 6923160 TI - Law for the nurse manager: the right of informed refusal. PMID- 6923161 TI - Art and science of management: face to face. PMID- 6923162 TI - Heat exhaustion in tractor drivers. PMID- 6923163 TI - Safety: anaesthetic hazard in operating theatres. PMID- 6923164 TI - Health screening: 2. PMID- 6923165 TI - Occupational safety: why do accidents happen? PMID- 6923166 TI - Safety in the health care industry. PMID- 6923167 TI - Designing the workplace for health and safety: biomechanical considerations. PMID- 6923168 TI - Safety hazards in the office: appearances can be hazardous. PMID- 6923169 TI - Personal protective equipment: design and availability considerations. PMID- 6923170 TI - Safety hazards as occupational stressors: a neglected issue. PMID- 6923171 TI - Improving safety and health through collective bargaining. PMID- 6923174 TI - Use of occupational health setting for nursing student experiences. PMID- 6923172 TI - Is there a correlation between occupational stress and physical disease and mental symptoms in upper level management? PMID- 6923173 TI - Building an occupational health unit library. PMID- 6923175 TI - The occupational health nurse of the future. PMID- 6923176 TI - Rights of psychiatric patients. PMID- 6923178 TI - Schorr tells nurses how to get their act together. PMID- 6923177 TI - Nutrition against disease: the choice is yours. PMID- 6923180 TI - [Report on a university course for faculty nursing personnel 1981/82]. PMID- 6923179 TI - [Is nursing care measurable? - Value and evaluation]. PMID- 6923182 TI - [Nursing documentation--its realization on the ward]. PMID- 6923181 TI - [Aging]. PMID- 6923183 TI - A review process that assures quality continuing education. PMID- 6923184 TI - [Interrelation of the function of the blood kallikrein-kinin system with the basic parameters of central hemodynamics in hypertension]. PMID- 6923185 TI - Oxygen exposure in the newborn guinea pig lung lavage cell populations, chemotactic and elastase response: a possible relationship to neonatal bronchopulmonary dysplasia. AB - Neonatal guinea pig pulmonary response to oxygen exposure FiO2 greater than 0.9 resulted in an increase in total cell number in lung lavage. Alveolar macrophages initially increased within 48 h of exposure. Polymorphonuclear leukocytes and macrophages exceeded age-matched neonatal control values by 72 h of oxygen exposure. By 144 h of life, total inflammatory cell number still exceeded control cell populations. Chemotaxis of alveolar macrophages to N-formyl-methionyl phenylalanine (1 x 10(-5) M) exceeded chemotaxis of air-exposed controls. Although initially depressed, by 72 h of FiO2 greater than 0.9 polymorphonuclear leukocyte chemotaxis increased 6-fold. Endogenous chemotactic peptides were demonstrated in lung lavage supernatant of oxygen-exposed neonatal guinea pigs. Elastase activity rose in oxygen exposed guinea pigs by 72 h of life. Lung lavage disaturated phosphatidylcholine in oxygen-exposed neonates exceeded control values 4-fold. In a preliminary study, lung effluent elastase activity was found to be increased in human neonates with respiratory distress syndrome over the first days of life compared to infants intubated but without lung disease. In infants developing bronchopulmonary dysplasia, tracheal aspirate protease activity remained greater than 10(-3) U for over 10 days and up to 5 weeks of age. PMID- 6923186 TI - The role of forensic psychiatry and the insanity defense. PMID- 6923187 TI - Coping with drug abuse by children of the wealthy: a new high-risk group. PMID- 6923188 TI - Primary nursing in psychiatry: an effective and functional model. PMID- 6923189 TI - Therapeutic group work with abused preschool children. PMID- 6923190 TI - Premature developmental jumps: the effects of early intimacy on the adult lives of identical twins. PMID- 6923191 TI - A small study on how the staff of an inpatient psychiatric unit spends its time. PMID- 6923192 TI - The multiple personality. PMID- 6923193 TI - Repression in a case of multiple personality disorder. PMID- 6923194 TI - Administrative decision making: staff-patient ratios (a patient classification system for a psychiatric setting). AB - In this article, we have described a patient classification system in use at the C.F. Menninger Memorial Hospital. It is a type of factor evaluation, in which we use critical indicators or descriptors of care as units of measurement. Each critical indicator represents a grouping of nursing activities rather than concrete time measurement of each activity. The ten critical indicators of patient care needs and nursing activities which were identified were divided into two major categories: routine and extra. Each category was then subdivided to reflect a range or variation of care levels. This type of patient classification appears to have an advantage over other classification systems when applied to psychiatric nursing. The factor evaluations are broad enough in scope to allow inclusion of patient assessment, documentation, and use of the nursing process, while providing a measurement of psychological and psychosocial needs of the patient which are frequently absent in other classification systems that rely on task measurements or acuity levels alone. Because of its practicality it has been readily accepted by nurses working on psychiatric units, and the nurse administrator's effort to put a classification system in place has been made easier. PMID- 6923197 TI - Survival of the fittest: a management challenge for nursing. PMID- 6923195 TI - Actualizing theory in practice. PMID- 6923196 TI - RET: rational/emotive therapy--a cognitive-behavior treatment system. PMID- 6923198 TI - Survival of the fittest. PMID- 6923200 TI - NLN's role in the survival of nursing. PMID- 6923199 TI - Participative team-management through team-building training. PMID- 6923201 TI - Sexual harassment. PMID- 6923202 TI - The conflict of conservatism in public health nursing education. PMID- 6923203 TI - The computer in public health: today and tomorrow. PMID- 6923204 TI - A client classification system adaptable for computerization. PMID- 6923207 TI - Construct for public health nursing. PMID- 6923205 TI - Implications of the competition model. PMID- 6923208 TI - International nursing challenge. PMID- 6923209 TI - Acute, fulminating jargonitis. PMID- 6923206 TI - A holistic view of middle management. PMID- 6923213 TI - Clearing the chaos. 1. How the system would work. PMID- 6923210 TI - Training under scrutiny. PMID- 6923211 TI - Funding a face-lift. PMID- 6923212 TI - The shape of things to come. PMID- 6923214 TI - Clearing the chaos. 2. A manager's view. PMID- 6923216 TI - Clearing the chaos. 4. The Association of Health Careers Advisers' viewpoint. PMID- 6923215 TI - Clearing the chaos. 2. A head teacher's view. PMID- 6923217 TI - Present and future trends in the health care of British-Asian children. PMID- 6923218 TI - Budgetary control-the role of the director of nursing services and treasurers. PMID- 6923220 TI - Reminiscence groups. PMID- 6923219 TI - 'Children under 14 years are urged to visit these wards'. PMID- 6923221 TI - Systems of life No 93. Systems and signs: nervous system. Mental state. PMID- 6923222 TI - The Journal of Infection Control Nursing. Catering hygiene study day. PMID- 6923223 TI - The Journal of Infection Control Nursing. The Howie Report: what does it say for nurses? PMID- 6923225 TI - The Journal of Infection Control Nursing. Sterilisation. PMID- 6923224 TI - Health services in primary schools: the nurse's role-1. PMID- 6923226 TI - The Journal of Infection Control Nursing. At sixes and sevens. PMID- 6923227 TI - The Journal of Infection Control Nursing. The epidemiology of communicable diseases. PMID- 6923228 TI - Survival of the fittest? PMID- 6923229 TI - Degree course with a difference. PMID- 6923230 TI - Vision: queen of the senses. 1 - Optics of the eye. PMID- 6923231 TI - Computers: the new approach. A pocket computer in the ward. PMID- 6923232 TI - Computers: the new approach. Computers and staff allocation made easy. PMID- 6923233 TI - Dialogue 2. Values in nursing. PMID- 6923235 TI - First-line management training-does it work? PMID- 6923234 TI - Nursing at the crossroads - 3. Assessment of the patient's physical condition. PMID- 6923236 TI - Staffing a geriatric unit at morning peak hours. PMID- 6923237 TI - Health services in primary schools: the nurse's role--2. Conclusions. PMID- 6923238 TI - Child health supplement. Come together. PMID- 6923240 TI - The casualties of war. PMID- 6923239 TI - Child health supplement. The pain of separation. PMID- 6923241 TI - Vision. 2. How the eye regulates light entry. PMID- 6923242 TI - Becoming a health visitor--an obstacle course? PMID- 6923243 TI - Myelomatosis. PMID- 6923244 TI - Dialogue 3. Preaching and practising. PMID- 6923245 TI - Nursing at the crossroads. 4. The nurse and information giving. PMID- 6923246 TI - Training village midwives--key to a community health programme. PMID- 6923247 TI - Coffee pots, clean sheets and a star patient. PMID- 6923250 TI - Using computers to enhance professional practice. PMID- 6923251 TI - A family-oriented approach to community care for the elderly mentally infirm. PMID- 6923248 TI - Students vote for change. Interview by Graham Anderson. PMID- 6923252 TI - Therapeutic embolisation. PMID- 6923253 TI - Vision. 3. How the pressure is maintained and the consequence of glaucoma. PMID- 6923249 TI - When is a nurse not a nurse? PMID- 6923254 TI - Nursing at the crossroads--5. The role of the nurse in the future. PMID- 6923255 TI - Quantifying nursing. Is arithmetic enough? PMID- 6923256 TI - How objective are objective tests? Some uses of the computer in validating multiple-choice questions. PMID- 6923257 TI - A critical view of the validity of the therapeutic community. PMID- 6923259 TI - Wound care No. 13. The traumatic wounds of warfare. PMID- 6923258 TI - Objectives: courses and examinations. PMID- 6923260 TI - The use of behavioural objectives in nurse education. PMID- 6923261 TI - How the other half dies. PMID- 6923262 TI - 291 Harrow Road. PMID- 6923263 TI - Vision. 4. Chemicals in the retina which initiate vision. PMID- 6923264 TI - The role of the hospital social worker. PMID- 6923266 TI - Nurse Smith's notes. Understanding drug treatment. 2. PMID- 6923267 TI - Spotlight on children. Behaviour therapy. PMID- 6923265 TI - Spotlight on children. Pay and prejudice. PMID- 6923268 TI - Nursing values and nursing action. PMID- 6923269 TI - Spotlight on children. Childhood hypertension. PMID- 6923272 TI - A mother's rights. PMID- 6923271 TI - Why do we do it? PMID- 6923270 TI - Spotlight on children. Mother and baby rooms. PMID- 6923274 TI - On the road: 'Will you weigh m'baby, lady?'. PMID- 6923273 TI - On the road: reflections on travellers and their children. PMID- 6923276 TI - Looking back -1. PMID- 6923275 TI - Nursing care study: schizophrenia or not? PMID- 6923278 TI - Letter from America. PMID- 6923277 TI - Fire precautions - does your motivation need rekindling? PMID- 6923279 TI - Systems of life No 94. Systems and signs: nervous system. Coma. PMID- 6923281 TI - Theatre nursing supplement: a patient with malignant breast cancer. PMID- 6923280 TI - Theatre nursing supplement. You need hands. PMID- 6923283 TI - Theatre nursing supplement. An independent approach. PMID- 6923282 TI - What health visitors do. PMID- 6923284 TI - Theatre nursing supplement: a new technique in haemodialysis. PMID- 6923285 TI - Home sweet home. PMID- 6923287 TI - Information technology 82. This is the age of the computer. PMID- 6923286 TI - Industrial relations - the good news. PMID- 6923288 TI - Nursing care study: aching bones. PMID- 6923289 TI - GPs' views of community psychiatric nurses. PMID- 6923290 TI - Looking back--2. PMID- 6923291 TI - Preparation for retirement. PMID- 6923292 TI - Calling for assistance. PMID- 6923294 TI - A librarian for the small hospital. PMID- 6923295 TI - Could you care more? Observations of a grounded ward sister. PMID- 6923293 TI - Tea--the best drink of the day? PMID- 6923296 TI - Symposium on sexuality and nursing practice. PMID- 6923297 TI - Nursing practice in human sexuality. PMID- 6923298 TI - Role preparation for nurses in human sexual functioning. PMID- 6923299 TI - Influences of culture on sexuality. AB - Religion is a cultured phenomenon, a subculture within our larger cultural system. Different religions have different teachings about what constitutes sexual morality, while members within a specific religious denomination may also have different beliefs and practices. Religiosity, or acceptance of the teachings of a particular religion, is more important as a determinant of sexual behavior than a specific religion per se. Orthodox Judaism, traditional Catholicism and traditional Protestantism are alike in their condemnation of masturbation, abortion, homosexuality, and premarital and extramarital coitus. More liberal members of these religions may not tolerate these activities, but may espouse them as necessary means to maintain or attain health. Nurses assess the beliefs that clients hold in regard to sexual morality and also identify if the client is experiencing guilt about past sexual practices. Interventions are planned with the client within the framework of the client's religious and spiritual beliefs and practices. To do otherwise is to invite distrust and distress in the client. Nurses intervene with sensitivity, compassion, and respect for beliefs and values that may be different from their own. PMID- 6923300 TI - Developmental disability and human sexuality. PMID- 6923301 TI - Diabetes and sexual functioning. PMID- 6923302 TI - Sexual stress: coping and adaptation. PMID- 6923303 TI - Human Sexuality and spinal cord injury. PMID- 6923304 TI - Sexuality and aging. PMID- 6923305 TI - Symposium on patient compliance. PMID- 6923306 TI - Patient participation in nursing process. PMID- 6923307 TI - The nurse: also an educator, patient advocate, and counselor. PMID- 6923308 TI - The patient: a partner in the health care process. PMID- 6923309 TI - Identifying the real patient problems. PMID- 6923311 TI - Assessing adherence in stroke victims. AB - A stroke rehabilitation unit or designated hospital beds for the purpose of implementing a stroke rehabilitation program is an effective way to achieve patient compliance. The program should be structured to support the fact that most patients recover most of their spontaneous improvement of brain and motor function by the time they are discharged from the hospital. The overall goal of the program is to provide a consistent rehabilitative approach to improve and maintain patient compliance with a prescribed regimen. Patient compliance is directly related to the patient's perception and knowledge of the disease, his physical condition, and the prescribed therapy. It is important that the program address itself to these three areas. Key activities that enhance the stroke patient's compliance include education of the patient and patient contracting. The stroke rehabilitation program is also evaluated in terms of satisfaction of the patient and the staff. The preservation, promotion, and restoration of health are the rights of every stroke patient. The scope of rehabilitation will continue to reflect the need for developing alternative methods of assisting patients in restructuring their patterns of living. The development of a stroke rehabilitation unit is a step in that direction. PMID- 6923310 TI - Predicting, measuring, implementing and following up on patient compliance. PMID- 6923312 TI - Compliance challenges in a Black Lung Clinic. PMID- 6923314 TI - G N M School of Nursing: school improvement plan. PMID- 6923316 TI - Vital aspects of nursing: primary health care. PMID- 6923317 TI - Vital aspects of nursing: community health nursing. PMID- 6923315 TI - Vital aspects of nursing: curriculum and its implementation. PMID- 6923313 TI - Patient compliance in rehabilitative programs. PMID- 6923318 TI - Vital aspects of nursing. Dais: traditional health attendants. PMID- 6923319 TI - Vital aspects of nursing: the family planning component. PMID- 6923320 TI - Vital aspects of nursing. Psychiatric nursing. PMID- 6923321 TI - Vital aspects in nursing: facing disaster situations. PMID- 6923322 TI - A question of conscience. It's time to make amends. PMID- 6923323 TI - Don't let this killing disease return. PMID- 6923327 TI - Cushing's syndrome. PMID- 6923325 TI - Psychiatry/mental handicap forum. 9. Return to the world of everyday living. PMID- 6923324 TI - Ethics: of concern to us all. PMID- 6923326 TI - Psychiatry/mental handicap forum. 9. A secure environment. PMID- 6923328 TI - The art of observation. 5. Satisfy basic needs first. PMID- 6923329 TI - Immigration: husband or home? PMID- 6923330 TI - Notifiable infectious diseases. 4. No room for complacency. PMID- 6923331 TI - Pacemakers: mature unit for prematurity. PMID- 6923332 TI - Nursing care study: shutting out the world. PMID- 6923333 TI - Beyond the class of the plastic dolls. PMID- 6923336 TI - Middle management: the chain of command. PMID- 6923335 TI - Nursing care study: clearing a pathway. PMID- 6923334 TI - The spinal cord. PMID- 6923337 TI - Every time she woke up my heart sank. PMID- 6923338 TI - Enrolled nurses: the outlook for SENs. PMID- 6923340 TI - Geriatric nursing: sorry I haven't got time. PMID- 6923339 TI - Careers: dermatology nursing. PMID- 6923341 TI - Management. 3. Supporting the manager. PMID- 6923342 TI - Obstructive jaundice. PMID- 6923343 TI - Stress: self-awareness. PMID- 6923344 TI - Stress: hidden connections. PMID- 6923345 TI - Management forum 4: Theory and practice. Why this dilemma? PMID- 6923346 TI - Management forum 4: Theory and practice. Responsibility-the key word. PMID- 6923347 TI - Nursing care study: the big sleep. PMID- 6923348 TI - Anytown anecdotes: Making life difficult. PMID- 6923349 TI - Talking points on conference. PMID- 6923353 TI - The riddles of the myelin sheath. PMID- 6923351 TI - Towards professionalism: time to speak our minds. PMID- 6923352 TI - Residential homes: beware of the nurses. PMID- 6923350 TI - Non-notifiable infectious diseases: no need to report. PMID- 6923354 TI - Nursing care study: she never asked for anything. PMID- 6923355 TI - Social work: a muffled cry for co-operation. PMID- 6923356 TI - Lay midwifery in America: free love, birth and midwives. Interview by Kate Newson. PMID- 6923357 TI - Night duty: the nursing process in dimmed lights. PMID- 6923358 TI - Down Memory Lane: Room 80-and after. PMID- 6923359 TI - Careers: nurse tutor training. PMID- 6923360 TI - Carcinoma of the thyroid gland. PMID- 6923361 TI - Survival kit for managers. 1. Sink or swim. PMID- 6923363 TI - I was being fed false information. PMID- 6923362 TI - Batter the pillow instead. PMID- 6923365 TI - Theatre nursing. PMID- 6923364 TI - Emergency surgery for the newborn. PMID- 6923366 TI - Living in a camp: a place of refuge. PMID- 6923370 TI - In-service education: changing staff attitudes. PMID- 6923371 TI - Nursing care study: living on the inside. PMID- 6923368 TI - The art of observation. 7. In the light of present knowledge. PMID- 6923367 TI - Stress can kill. PMID- 6923369 TI - Issues in nursing. 10. The forgotten nine thousand. PMID- 6923373 TI - Thalassaemia. PMID- 6923372 TI - Enzyme reactions. PMID- 6923374 TI - Ward routine: a change is as good as a rest. PMID- 6923375 TI - Death: a fact of life. PMID- 6923376 TI - Legislation: rights for mentally ill patients. PMID- 6923377 TI - It's changed a bit since the thirties. PMID- 6923378 TI - Careers: district nursing. PMID- 6923379 TI - While the bombs fell. PMID- 6923380 TI - Acute osteomyelitis. PMID- 6923382 TI - Survival kit for managers. 2. Plotting the dimensions of leadership. PMID- 6923381 TI - Smoking, stress and nurses. PMID- 6923383 TI - The art of observation. 8. The importance of sensitivity. PMID- 6923384 TI - Nursing in Japan: in the land of the Rising Sun. PMID- 6923385 TI - Organisation is the key. PMID- 6923386 TI - Community forum. 10. Professional insecurity. PMID- 6923387 TI - Community forum. 10. A team of supporters. PMID- 6923388 TI - Bitter-sweet time on the ward. PMID- 6923389 TI - Stress. 3. Dare you say no? PMID- 6923390 TI - Stress. 3. Identifying the cause. PMID- 6923392 TI - Theatre nurses: tomorrow's world. PMID- 6923393 TI - A mind disordered: the public view. PMID- 6923391 TI - Nursing care study: a model of patience. PMID- 6923394 TI - Coronary care unit: affairs of the heart. PMID- 6923395 TI - Anytown anecdotes: a simple injection. PMID- 6923396 TI - Nursing care study: make or break. PMID- 6923398 TI - The tide has turned. PMID- 6923397 TI - Careers: psychiatric nursing. PMID- 6923399 TI - The art of observation. 9. Eat, drink but think of tomorrow. PMID- 6923400 TI - Retinitis pigmentosa. PMID- 6923401 TI - Clinical forum. 10. Urology: disorders of the male genitourinary tract. PMID- 6923402 TI - Clinical forum. 10. Urology: nursing management. PMID- 6923403 TI - The patient's progress. PMID- 6923404 TI - Stress. 4. Do you care about your colleagues? PMID- 6923405 TI - Stress. 4. Effective diagnosis. PMID- 6923406 TI - Survival kit for managers. 3. The nursing budget. PMID- 6923408 TI - International critical care conference: cause and effect. PMID- 6923407 TI - Putting ideas into action. PMID- 6923409 TI - Psychology: look back in anger. PMID- 6923410 TI - Cytology: 3. Hormonal status of women. PMID- 6923411 TI - Careers: the nursing officer. PMID- 6923412 TI - Management of the patient receiving hemibody irradiation. PMID- 6923413 TI - Nursing care for the patient with an Ommaya reservoir. PMID- 6923414 TI - Anti-estrogen therapy for breast cancer: focus on tamoxifen. PMID- 6923416 TI - Cancer patients' perceptions of five psychosocial needs. PMID- 6923415 TI - Needs assessment for advanced cancer patients and their families. PMID- 6923417 TI - A care orientation to clinical nursing research. PMID- 6923418 TI - The role of the areawide oncology nurse coordinator in the home care of cancer patients. PMID- 6923419 TI - Home care of the Hickman/Broviac catheter. PMID- 6923420 TI - Learning to care for your Hickman/Broviac catheter. PMID- 6923421 TI - Report of the task force on certification in oncology nursing: Oncology Nursing Society Certification Survey. PMID- 6923423 TI - Painful tendon problems of the hand: trigger thumb, trigger finger and de Quervain's syndrome. PMID- 6923424 TI - Transport traction. PMID- 6923422 TI - Musculoskeletal assessment: range of motion of the fingers and hand. PMID- 6923425 TI - Professional development: anatomy of an interview. PMID- 6923426 TI - Scoliosis terminology. PMID- 6923428 TI - Primary health care: the Philippine Nurses' experience. PMID- 6923429 TI - International Council of Nurses policy statements. PMID- 6923427 TI - Orienting the float team to orthopedic patient care. PMID- 6923430 TI - On health and human rights. PMID- 6923431 TI - Collective action by nurses. PMID- 6923433 TI - Telephone medicine: documentation vital. PMID- 6923434 TI - RN's and criminal assault: legal rights. Case in point: Name v. Southern Baptist Hosp. et al (415 So. 2d 993 - LA). PMID- 6923432 TI - Nuclear plants and safety of human environment--nurses' challenge. PMID- 6923435 TI - Legal case briefs for nurses. PA: $550,000 award; post-op errors; OR: $358,888.75 awarded in suicide. PMID- 6923437 TI - Professional nursing education: no sex barriers. PMID- 6923436 TI - Intensive care nursing: doctor problems. Case in point: Poor Sisters v. Catron (435 N.E. 2d 305 - IN). PMID- 6923438 TI - Legal case briefs for nurses. IL: OBS: caesarean and appendectomy. MO: Psyc: force-medicating mental patients. PMID- 6923439 TI - Ambulances and hospitals: legal overtones. Case in point: Wright v. United States (537 F. Supp. 568 - IL). PMID- 6923440 TI - Professional socialization to a research role: interest in research among graduate students in nursing. AB - This study was conducted to determine whether graduate coursework in research methods and statistics resulted in socializing graduate students in nursing into a research role. Two cohorts, each of about 60 female graduate students in nursing, completed self-administration questionnaires at three different times during their 6 month coursework in research methods and statistics. Subjects indicated significantly more interest in research methods than in statistics (p less than .01), although they rated statistics as valuable to nursing. At the beginning of graduate work, subjects with more work experience in nursing were significantly more interested (p less than .05) in conducting research. Graduate coursework in research methods and statistics produced no significant change in students' interest in doing research in their future nursing careers. PMID- 6923441 TI - Toward a construct of perimenstrual distress. AB - Recent research findings contradict the notion that premenstrual and menstrual symptoms constitute two mutually exclusive categories of perimenstrual distress. The purposes of this study were to describe the prevalence of distress associated with menstruation in a community population and to determine whether perimenstrual distress could be regarded as a single construct. Nonpregnant women (N = 193) between 18 and 35 were selected from five neighborhoods in a southeastern city in a way that allowed for variability in race and income. The women were interviewed in their homes and 179 were asked to complete the Moos Menstrual Distress Questionnaire (MDQ). At least 30% of the women reported weight gain, skin disorders, backache, painful or tender breasts, irritability, depression, headache, cramps, fatigue, swelling, mood swings or tension in the perimenstruum. Cycle phase differences were not found for 31 MDQ symptoms, but were found for: weight gain, crying, lowered school or work performance, taking naps, headache, skin disorders, cramps, anxiety, backache, fatigue, painful or tender breasts, swelling, irritability, mood swings, depression, and tension. Although there were significant differences between the premenstrual and menstrual phases for certain symptoms, the magnitudes of the mean differences were small (less than .3) except for cramps, weight gain, and fatigue. Furthermore, premenstrual and menstrual reports of the same symptoms were highly correlated. Thus, it appears reasonable to study perimenstrual distress as a single construct. PMID- 6923442 TI - Ratings of physical and mental health in the older bereaved. AB - Subjective and objective ratings of mental and physical health were compared, using data from a larger study of older bereaved persons. Variation by age, race, and sex of subjects also was investigated. Sixty widowed individuals, aged 58-83, whose spouses died within the previous three months were identified through death certificates. Subjects were interviewed in their homes using a modification of the older Americans' Resources and Services, Multidimensional Functional Assessment Questionnaire (OARS), which provides objective and subjective ratings of mental and physical health. The Zung Self-Rating Depression Scale was used to quantify intensity of depression. Subjective ratings of physical health are primarily positive and significantly better than the objective ratings, particularly for women. In general, subjective and objective ratings of mental health do not differ. Interviewer ratings of physical health show significant variation by age of subjects rated. Findings are discussed in terms of reference group comparisons and of implications for design and interpretation of morbidity studies of widowed. PMID- 6923444 TI - Stressful life events and illness onset: a review of crucial variables. PMID- 6923443 TI - The nurse as a sex object in motion pictures, 1930 to 1980. AB - A content analysis of 191 motion pictures featuring 211 nurses as significant characters was conducted to determine the nature and extent of the motion picture industry's depiction of the nurse as a sex object and to identify changes in that portrayal from 1930 to 1980. Seventy-three percent of the nurse roles characterized nurses as sex objects. The frequency and intensity of stereotypes of nurses as sex objects rose significantly during the 1960s and 1970s (p less than .0001). Exploitation of the nurse as a sex object was more common in the larger nurse roles. However, in films with a strong emphasis on professional nursing in either the story or in character development, sexual stereotyping of nurses was uncommon. It was concluded that the image of the nurse as a professional care giver was incompatible with that of the nurse as sex object, and that the motion picture industry has opted primarily to present the latter image. The extremely negative sexual stereotype of nursing promulgated during the past 20 years is cause for concern. Actions that the nursing profession can employ to counter the unfavorable portrayal of nurses in 1980s motion pictures are suggested. PMID- 6923445 TI - [What I learned in living with orphaned children]. PMID- 6923446 TI - [Problems of the hospitalized child and how they affect the community]. PMID- 6923447 TI - [Effect of nutritional state on the duration of the estrus cycle in rats]. PMID- 6923449 TI - [Utilization of periodicals in the library of the University of Sao Paulo School of Nursing]. PMID- 6923448 TI - [Nursing interventions and their importance according to nurses and to geriatric patients]. PMID- 6923450 TI - [Cognitive needs of families of contagious patients hospitalized in isolation units]. PMID- 6923451 TI - [Manipulative behavior and the therapeutic relationship]. PMID- 6923453 TI - [Nursing care in the field of immunization]. PMID- 6923452 TI - [Health education in a pediatric outpatient clinic]. PMID- 6923454 TI - [Project on postbasic nursing studies in specialty care]. PMID- 6923455 TI - [Nursing care process: data collected in an emergency of an extensive burn]. PMID- 6923456 TI - [Lumbar puncture]. PMID- 6923458 TI - [Preventive medical services and hospital hygiene]. PMID- 6923457 TI - [Study of urostomy bags with improved karaya and micropore, series 143]. PMID- 6923459 TI - [Changes in adolescent behavior]. PMID- 6923460 TI - [Nutrition of the pregnant woman]. PMID- 6923461 TI - [Medullary lesions. II]. PMID- 6923463 TI - [Universal religious aspects and psychiatric care]. PMID- 6923462 TI - [Interpersonal relations and their development in psychiatric care]. PMID- 6923464 TI - [Social significance of psychiatric institutions]. PMID- 6923465 TI - [Distinct concepts of and approaches to the mental patient]. PMID- 6923467 TI - [Nutrition of the pregnant woman]. PMID- 6923466 TI - [Relationship between social sciences and nursing]. PMID- 6923468 TI - [Specialization of pediatric nursing. Collected experiences over 5 years of development of the specialty]. PMID- 6923470 TI - [Kinesitherapy in pulmonary surgery]. PMID- 6923469 TI - [Interview with Doctor Luis Daufi, General Director of Health Promotion and Director of the Institute of Health Studies of the Cataluna district]. PMID- 6923471 TI - [Medullary lesions. III. Sexuality]. PMID- 6923472 TI - [Psychological importance of sexuality in the paraplegic patient]. PMID- 6923473 TI - [Alcoholic embryofetopathy]. PMID- 6923474 TI - [A survey of health consumption]. PMID- 6923475 TI - [Psychiatric nursing. Role of the psychiatric nurse]. PMID- 6923476 TI - [Nursing care to the patient with an amputation at the femoral level]. PMID- 6923477 TI - [Antiseptics and disinfectants]. PMID- 6923478 TI - [Medullary lesions. IV. Psychology of the patient with a permanent physical handicap]. PMID- 6923479 TI - [Psychological aspects of the paraplegic patient]. PMID- 6923481 TI - [Suffocation]. PMID- 6923482 TI - [Urography or radiologic examination of the urinary apparatus. Concepts, indications, technics and reactions]. PMID- 6923483 TI - [The nurse between theory and practice]. PMID- 6923480 TI - [Atmospheric disinfection by chemical methods]. PMID- 6923486 TI - Government report on nursing shows a booming profession. PMID- 6923485 TI - [Ambulatory nursing]. PMID- 6923484 TI - [The lactating woman. Dietetics]. PMID- 6923487 TI - How to rise above the cross-fire of a union/hospital battle. PMID- 6923488 TI - National opinion poll shows a wary new welcome for unions. PMID- 6923489 TI - Diabetes today: a very different diet: a new generation of oral drugs. CE elective. PMID- 6923490 TI - Foot care for the high-risk patient. PMID- 6923492 TI - Anatomy audit: the stomach. PMID- 6923491 TI - Beyond electrolytes. Solving the mysteries of calcium imbalance: an action guide. PMID- 6923493 TI - A pragmatic approach to musculoskeletal assessment. PMID- 6923494 TI - Mark's secret was death. PMID- 6923495 TI - Getting the most from chest x-rays and lung scans. PMID- 6923496 TI - What to watch for with clonidine and methyldopa. PMID- 6923497 TI - Why not use a Foley? PMID- 6923498 TI - Legally speaking: the deadly toll of communication failure. PMID- 6923499 TI - Early miscarriage: are we too quick to dismiss the pain? PMID- 6923500 TI - Your personal health: safe exposure levels for anesthetic gas. PMID- 6923501 TI - Understanding RNABC finances. PMID- 6923502 TI - If you have to look for a job. Job search tips. PMID- 6923505 TI - [An occupational disease: viral hepatitis]. PMID- 6923504 TI - [Viral hepatitis and prevention]. PMID- 6923506 TI - [Prevention of hepatitis B for staff members in a hemodialysis unit]. PMID- 6923503 TI - [Chronic viral hepatitis]. PMID- 6923507 TI - [Prevention of hepatitis in a hemodialysis unit]. PMID- 6923508 TI - [Morphological technics in the exploration of the biliary tract]. PMID- 6923509 TI - [Serology and epidemiology of viral hepatitis]. PMID- 6923512 TI - [Accompanying a cancer patient towards death]. PMID- 6923510 TI - [Biliary drainage: technics and monitoring]. PMID- 6923511 TI - [Visceralgine]. PMID- 6923513 TI - [Acute viral hepatitis]. PMID- 6923514 TI - [Drug use: complications and their treatment]. PMID- 6923515 TI - [Therapy of heroin dependence]. PMID- 6923516 TI - [Weaning the drug addict]. PMID- 6923517 TI - [Toxicomanias]. PMID- 6923519 TI - [Management of drug addicts in a medico-psychologic center of a regional university hospital center]. PMID- 6923518 TI - [Use of clonidine in weaning opiate addicts: possibility of ambulatory weaning]. PMID- 6923520 TI - [Institutions for drug addicts]. PMID- 6923521 TI - [Substances implicated in toxicomanias and toxicophilias]. PMID- 6923522 TI - [Violence of the drug addict and therapeutic institutions]. PMID- 6923523 TI - [Nurses' awareness of toxicomanias]. PMID- 6923524 TI - [Role of the nurse in a health care facility for drug addicts]. PMID- 6923525 TI - [If one knew what migraine is]. PMID- 6923526 TI - [Information on the subject of toxicomanias]. PMID- 6923527 TI - [Legislation and toxicomania]. PMID- 6923528 TI - [The European Council reinforces the campaign against drugs]. PMID- 6923530 TI - [A caring attitude among so many others. Testimony of a nurse]. PMID- 6923529 TI - [Alcohol and youth]. PMID- 6923533 TI - [Schizophrenia and chronic states of delirium]. PMID- 6923532 TI - [Mental disorders and organic diseases in Africa]. PMID- 6923531 TI - [Substance inhalation]. PMID- 6923534 TI - [Mental pathology in Africa]. PMID- 6923535 TI - [Agitation attacks and their treatment]. PMID- 6923540 TI - [Fits of delirium in Africa]. PMID- 6923538 TI - [Nurse-patient relations in psychiatry]. PMID- 6923541 TI - [Female contraception: hormonal methods]. PMID- 6923536 TI - [Psychiatric drugs]. PMID- 6923537 TI - [Electroshock: technics and indications]. PMID- 6923539 TI - [Depression in Africans]. PMID- 6923542 TI - [Postcoital contraception (or morning-after contraception)]. PMID- 6923543 TI - [Male contraception]. PMID- 6923544 TI - [Being well informed in order to inform well]. PMID- 6923545 TI - [Contraception consultation. Choice of contraception method]. PMID- 6923546 TI - [Psychological aspects of contraception]. PMID- 6923547 TI - [The medical auxiliary and contraception]. PMID- 6923549 TI - [Future perspectives in contraception]. PMID- 6923553 TI - [Management and guidance of personnel groups in the hospital]. PMID- 6923550 TI - [Non-hormonal methods of female contraception]. PMID- 6923551 TI - [Stimulating the small child]. PMID- 6923552 TI - [A polyvalent pediatric hospital experience]. PMID- 6923548 TI - [Role of the marriage counselor in contraception]. PMID- 6923554 TI - [Cross-professional advisory group in terminal care]. PMID- 6923555 TI - [Mental developmental retardation--responsibility and provision in the local environment]. PMID- 6923556 TI - [Development of professional information]. PMID- 6923557 TI - [Extraordinary national meeting: society members' report 1981-82]. PMID- 6923558 TI - [Nursing students' opinion on: nursing home patients in the surgical ward]. PMID- 6923559 TI - [Imprisoned Polish nurse adopted by colleagues in Tromso]. PMID- 6923560 TI - [Pollution by anesthesia gases: occupational health risk for anesthesia personnel]. PMID- 6923563 TI - [Refugee women's encounter with Norwegian health system]. PMID- 6923562 TI - [Following the extraordinary national meeting: more democratic management--but decentralized costs]. PMID- 6923561 TI - [Home birth in the hospital. Report of a study tour to Sweden and Signe Jansson's delivery department]. PMID- 6923564 TI - [Nursing school in Tanzania's bush country]. PMID- 6923565 TI - [Heroism--a nursing value?]. PMID- 6923567 TI - [A factor to be reckoned with: natural medicine in the future health care system]. PMID- 6923566 TI - [Nursing does not satisfy patients' basic needs]. PMID- 6923568 TI - [The incompetent patient]. PMID- 6923569 TI - [Health policy for the 80s]. PMID- 6923570 TI - [Goal and realities for home nursing care]. PMID- 6923572 TI - [Does the Norwegian Nurses' Association come under one large umbrella?]. PMID- 6923571 TI - [Another type of institution: rehabilitation department in Namdal hospital]. PMID- 6923576 TI - [Why a nursing theory?]. PMID- 6923575 TI - [While waiting for death. Shocking document from a Swedish long term care ward]. PMID- 6923573 TI - [Important future step for Norwegian nursing]. PMID- 6923577 TI - [Education department reports: public approval of the conditions of the new changes]. PMID- 6923574 TI - [From a study in Rogaland: how do we handle the relatives?]. PMID- 6923578 TI - [Guidelines from the Hygiene Group for the Ostland district: disinfection and cleaning of oxygen equipment]. PMID- 6923579 TI - [Finnish health care workers have gotten their umbrella organization]. PMID- 6923580 TI - [Nursing care at life's end]. PMID- 6923582 TI - [Supervision - systematic guidance]. PMID- 6923581 TI - [The aged patient]. PMID- 6923584 TI - [Professional conditions under a tight economy]. PMID- 6923586 TI - [Change in nursing care needs. A study from Lambertset Hospital 1979-1982]. PMID- 6923583 TI - [Dialogue between teacher and student: project-oriented instruction and participant guidance]. PMID- 6923587 TI - [Service department reports: reorganization of the Social Department/Bureau of Health]. PMID- 6923588 TI - [Research - a challenge to nursing practice. From the first open conference in nursing research]. PMID- 6923585 TI - [Ostfold has studied: patient flow in home nursing care]. PMID- 6923589 TI - [From the Scandinavian Nursing Cooperative delegates' meeting 1982: Scandinavian nurses draft health policy for the 80s]. PMID- 6923590 TI - [Health monitoring for the aged - based on case-finding nurses]. PMID- 6923591 TI - [Health policy principle program in the Norwegian Nurses' Association]. PMID- 6923592 TI - [Labor unions' role in health services]. PMID- 6923593 TI - [Nurse in art school. My picture art gives me a surplus as a nurse. Interview by Pia Kristensen]. PMID- 6923594 TI - [Teamwork when technology shall reign]. PMID- 6923595 TI - [Interview with Sygeplejersken's editor about the Sundbyvang articles. The problem is not what we wrote but whether it is correct]. PMID- 6923596 TI - [Executive Board meeting 8-9 June. A lot of activity concerning education]. PMID- 6923597 TI - [Health Administration's memorandum on nursing home assistants]. PMID- 6923599 TI - [For lack of direction and for little real and systematic knowledge]. PMID- 6923600 TI - [End-of-term in Denmark's Nursing Colleges in Aarhus and Copenhagen: to have the potential to get context in nursing activities]. PMID- 6923601 TI - [Sundbyvang will now get improved standardization of nurses]. PMID- 6923598 TI - [Borderline values of hygiene are not observed]. PMID- 6923602 TI - [Residents exchange between Danish and Icelandic nursing homes. A fresh breath of air for residents and nursing staff]. PMID- 6923603 TI - [Advisory committee for education within the nursing field. Resolution by the committee in its meeting on 28 and 29 April 1981]. PMID- 6923604 TI - [Mothers' group provides solidarity and widened horizon]. PMID- 6923606 TI - [Membership democracy in a professional organization - what is what?]. PMID- 6923608 TI - [Common topic will provide common entrance to course in 1982]. PMID- 6923605 TI - [Truth disclosure in connection with life-threatening illness]. PMID- 6923609 TI - [Export cooperation between industry and the health sector]. PMID- 6923607 TI - [Danish Nursing Council's new 2d Vice-president: we must maintain that we also shall nurse. Interview by Pia Kristensen]. PMID- 6923610 TI - [Home nursing of the dying]. PMID- 6923611 TI - [Health Administration's annual report]. PMID- 6923612 TI - [The dying have many more resources than mostly faith. Interview by Pia Kristensen]. PMID- 6923615 TI - [It doesn't make sense to distinguish oneself on such a slight foundation]. PMID- 6923613 TI - [Good combination: nurse and educator together]. PMID- 6923616 TI - [Commission on the Aged, 3d partial report: lack proposal for solution of the dilemma for nursing homes]. PMID- 6923614 TI - [Development of health and nursing care in an ambulatory clinic]. PMID- 6923619 TI - [Unrealistic perception of conditions in Danish nursing homes]. PMID- 6923620 TI - [Experiences from a practice period In a physician's office]. PMID- 6923621 TI - [Experiences from a 1-year continued education course for oncologic nurses: continued education with a sense of personal development]. PMID- 6923618 TI - [Children and hunger in Kenya are like the top of the iceberg]. PMID- 6923622 TI - [Nurses have learned to live with the problems]. PMID- 6923617 TI - [Conflict in hospitals: leave out first those you last want to affect]. PMID- 6923624 TI - [Working conditions so poor that they should intervene]. PMID- 6923623 TI - [Interviews with cancer patients]. PMID- 6923625 TI - [Sexual function and cancer]. PMID- 6923626 TI - [Care of cancer patients - a psychological burden. 1. Nurses often stand by with feelings of helplessness]. PMID- 6923628 TI - [Student Nurses' Cooperative Council 1982: additional effort to advance students' viewpoint]. PMID- 6923627 TI - [Care of cancer patients - a psychological burden. 2. The unconscious dissociation from patients]. PMID- 6923629 TI - [Around-the-clock care in Aabenraa: it is natural to also nurse our patients after 6 pm]. PMID- 6923630 TI - [Interview with the new director of the Pension Fund Administrative Office: we are aware of simplifications and errors from the political quarter]. PMID- 6923632 TI - [Interview with Dr. Marie Farrell, WHO: one should question what will be attained with nursing]. PMID- 6923631 TI - [Student nurses on changed organization of education in health and nursing care of children and adolescents: we have gotten knowledge and understanding in perspective]. PMID- 6923633 TI - [Statement for the setting up of the planning model for nursing education's practical part: a quantitative study of the practice possibilities]. PMID- 6923634 TI - [Report from an ambulatory care clinic in East Africa]. PMID- 6923635 TI - [Danish Nursing Council's new education center: white buildings around a 107-year old ginkgo tree]. PMID- 6923636 TI - [One cannot tolerate there conditions in the long run]. PMID- 6923637 TI - [Great importance of sociomedical aspects, disease prevention and health promotion in education of health and nursing care for children and adolescents: students can use each other's experience in group activities]. PMID- 6923638 TI - [Executive Board meeting 10-11 August 1982. Recruitment for nursing homes continually followed]. PMID- 6923639 TI - [Health Administration on radiographists' competence and responsibility: delegation of tasks needs careful instructions]. PMID- 6923641 TI - [Hospital acquired tract infections and bladder catheterization. We have a responsibility to limit catheterization]. PMID- 6923642 TI - [Home care nursing for Vesterbro in Copenhagen: changed framework means raised nursing care quality]. PMID- 6923643 TI - [We risk overplaying our cards]. PMID- 6923644 TI - [Prevention for young children in Denmark. 10. Evaluation of children's examinations among consumers]. PMID- 6923645 TI - [Inauguration of the Vilvorde Course center: pension arrangements sensitive thing rough hands can grope for]. PMID- 6923640 TI - [Study of anesthetic gases concern of the Labor inspection district, Aarhus county, Winter 1981-1982: anesthetic gases up to 13 times the allowable level]. PMID- 6923647 TI - [That's why we refrain from voting on the report]. PMID- 6923646 TI - [A mothers' group for Pakistani women in Norrebro: education and insight into a foreign community]. PMID- 6923648 TI - [Experience with a nursing home support group: added life content for residents and personnel]. PMID- 6923649 TI - [Revised information from Health Administration: head lice in children occurs with continued frequency]. PMID- 6923650 TI - [Reaction on the article about community health nurse's visit to pregnant women: we should recognize our own expertise and limitations]. PMID- 6923651 TI - [Community health nurses' comment on the article about mothers' groups: closer contact for parents with home visits]. PMID- 6923652 TI - [Safer handling of hazardous substances]. PMID- 6923654 TI - [Negotiations for arrangements and agreements 1983: new cooperation provides public employment with more power. Interview by Pia Kristensen]. PMID- 6923655 TI - Low-dose heparin in thoracic surgery: effect on blood coagulation and fibrinolysis system. AB - Plasma kallikrein, antithrombin III and antiplasmin were determined with chromogenic methods in 29 patients pre-, per- and post-operatively in a controlled, randomized study. 16 patients received calcium heparin, 5000 IU s. c. every 8 hr for 7 days, the first administration given 2 hr before surgical procedure. 13 control patients received saline. A significant reduction of kallikrein and antiplasmin in per- and post-operative periods was observed in the control patients compared with the heparin-treated patients, while there was a significant reduction of anti-thrombin III in the control patients compared with the treated patients only in the per-operative period. The results obtained suggest that activation of the coagulation and fibrinolysis system occurs in patients undergoing thoracic surgery, and that it is inhibited significantly by calcium heparin prophylaxis. PMID- 6923656 TI - Influence of heparin; of different heparin fractions and of a low molecular weight heparin-like substance on the mechanism of fibrinolysis. AB - The influence of different heparin fractions and of a synthetic polysulfated polysaccharide (SP54) on the fibrinolytic mechanism was examined. In vitro, a significant shortening of the euglobulin lysis time (ELT) was found after addition of standard mucosa heparin, of high MW heparin and of SP 54 respectively. Low MW heparin fractions had no influence on the ELT. Simultaneously with the shortening of the ELT an activation of factor XII and of kallikrein was observed. A similar effect was found in groups of volunteers after i.v. or s.c. injections and even after oral administration of SP 54. The effect of venous occlusion on the ELT and on the activation of factor XII was considerably increased when heparin or SP 54 was injected 2 h prior to the test. When a comparable concentration of the test substances was added to plasma samples before and after venous occlusion, the effect on the ELT was much less pronounced than after injection whilst the effect on factor XII was comparable in both tests. From these results the conclusion was drawn that activation of fibrinolysis by polysulfated polysaccharides is achieved by an endogenous pathway as well as by an increased availability of the vascular activator. The magnitude of the activation of fibrinolysis partly depends on the MW of the substance but apparently also on the degree of sulfation since a low MW substance with a high number of sulfate bonds such as SP 54 was considerably more active than the low MW fraction of standard heparin. PMID- 6923653 TI - [Overoccupancy of Copenhagen's hospitals: 10 nurses have not had a normal pregnancy]. PMID- 6923657 TI - [Professional structure of nursing abroad]. PMID- 6923658 TI - [Prevention of dismissal of student nurses]. PMID- 6923659 TI - [Nursing education has a future]. PMID- 6923660 TI - [A reaction to the critical analysis of Van den Brink-Tjebbes' concepts]. PMID- 6923661 TI - [Oral rehydration--a revolution in diarrhea treatment]. PMID- 6923662 TI - [The graduate nurse with Higher Professional Education in the practical situation]. PMID- 6923663 TI - [Nurses and medical authority. I]. PMID- 6923664 TI - [Notes on 'Support of self care the nature of nursing?']. PMID- 6923665 TI - [Drug information for nursing personnel in a nursing home]. PMID- 6923666 TI - [Bottlenecks in the field of nursing]. PMID- 6923667 TI - [Theory developments in nursing]. PMID- 6923668 TI - [Nurses and medical authoritarianism. II]. PMID- 6923669 TI - [Who is still afraid of the pill today? The development of hormonal contraception ('the pill') in the last 20 years. Current status]. PMID- 6923670 TI - [A patient with hypothermia]. PMID- 6923672 TI - Purchasing decisions--the hows & whys. PMID- 6923673 TI - Purchasing: communication builds the bridges. PMID- 6923671 TI - Early effects of intratracheal Instillation of elastase on mortality, Respiratory function, and pulmonary morphometry of F-344 rats. PMID- 6923674 TI - The OR supervisor's role in purchasing. PMID- 6923675 TI - Inventory control in the OR sector. PMID- 6923676 TI - Purchasing. OR nurses in a newly equipped unit--the World's Fair. PMID- 6923677 TI - Purchasing: Operating Room Products Standardization COmmittee of the Massachusetts General hospital. PMID- 6923678 TI - Perry. PMID- 6923679 TI - Promoting health at work. PMID- 6923680 TI - The employees responsibility for promoting health at work. PMID- 6923681 TI - The role of health education in promoting health at work. PMID- 6923682 TI - The nurse's responsibility in relation to smoking and health. PMID- 6923683 TI - Quality assurance: an introduction. PMID- 6923684 TI - All you wanted to know about drafting legislation but were afraid to ask. PMID- 6923686 TI - Nursing turnover syndrome. PMID- 6923687 TI - Cross--cultural consultation. PMID- 6923685 TI - Collective bargaining - a historical perspective. PMID- 6923688 TI - A quiet desperation. PMID- 6923689 TI - Is the future in our hands? A call to nurses. PMID- 6923690 TI - The nurse practitioner. PMID- 6923691 TI - The ability of participant laboratories to detect penicillin-resistant Pneumococci. A report from the microbiology portion of the College of American Pathologists (CAP) surveys. AB - To assess the ability of clinical laboratories to identify penicillin-resistant Streptococcus pneumoniae, a challenge sample was distributed to CAP Special Bacteriology surveys participants in 1981. Their performance was excellent (greater than 99%) for organism identification, but less than 15% of surveys subscribers that use the standardized disk diffusion test detected penicillin resistance. The recommendations of the NCCLS M2-A2S for 1-microgram oxacillin disk screening are discussed. The screening and dilution tests for detecting drug resistant S. pneumoniae seem to be accurate and the use of other disks, such as methicillin and nafcillin, also appear efficacious. Due to the clinical frequency of serious pneumococcal disease, all microbiology laboratories should be applying these screening procedures to appropriate patient isolates. PMID- 6923692 TI - Bendectin use during pregnancy. PMID- 6923693 TI - Post-traumatic stress disorder in Vietnam veterans. For some the war rages on. PMID- 6923694 TI - PTSD. The victims who survived. PMID- 6923695 TI - PTSD. A portrait of the problem. PMID- 6923696 TI - PTSD. An inpatient treatment unit. PMID- 6923697 TI - The neonatal ICU: a high-risk environment. PMID- 6923698 TI - Supplemental nursing services: who uses them? Who does not? PMID- 6923699 TI - Programmed instruction. Nursing care of patients in shock. Part 3: evaluating the patient. PMID- 6923700 TI - Dilemmas in practice. The choice: two experiences. An ethicist comments. PMID- 6923701 TI - So you want a cushy job... PMID- 6923703 TI - "Feedback: putting your best foot forward". PMID- 6923702 TI - Neurtrophil degranulation in cadmium-chloride-induced acute lung inflammation. AB - Lobar intrabronchial instillation of cadmium chloride (200 micrograms/ml) in saline causes a reproducible acute pulmonary inflammation in dogs. The influx of inflammatory neutrophils from the circulation into the alveolar spaces reaches a maximum approximately 16 hours after the cadmium chloride treatment in the treated lobe, while the controlateral lung appears normal. Morphometric quantitation of peroxidase-positive (azurophilic) granules in the inflammatory neutrophils shows a 74% loss of these granules, with little or no loss of the peroxidase-negative (specific) granules. These data are in good agreement with the measured loss of intracellular elastase, an enzyme known to be localized in the azurophilic granules. The results suggest that degranulation of azurophilic granules may occur selectively during this chemically induced acute inflammation. PMID- 6923704 TI - Continuing education do's and don't's. PMID- 6923705 TI - FTC jurisdiction vital, ANA urges members to act. PMID- 6923706 TI - NLRB rulings threaten labor efforts. PMID- 6923708 TI - Nurse managers can also run hospitals. PMID- 6923707 TI - ANA Bylaws. PMID- 6923709 TI - Membership is still key to success under federation. PMID- 6923710 TI - As I see it... Nurse finds membership pays--$22 plus benefits. PMID- 6923713 TI - Nursing practice or nursing profession? There is a difference. PMID- 6923711 TI - [Characteristics of the protein spectra of methicillin-resistant and methicillin sensitive staphylococcal strains]. AB - Differences in the protein-composition of methicillin resistant (MR) and methicillin sensitive (MS) staphylococci were shown by means of disk electrophoresis. Extracellular proteins of MR and MS staphylococci were studied electrophoretically. The study revealed no relation between the culture grouping by the protein spectra and resistance to methicillin. Comparison of the spectra of soluble intracellular proteins showed a certain correlation with methicillin resistance. PMID- 6923714 TI - Standards of perioperative nursing practice: using the revised standards. From the Committee on Nursing Practices. PMID- 6923712 TI - Factors influencing detection of tolerance in Staphylococcus aureus. AB - The phenomenon of tolerance to cloxacillin and methicillin was studied in Staphylococcus aureus. It was demonstrated that the minimal bactericidal concentrations showed marked differences, depending on the method of detection used. These differences resulted from carry-over of the antibiotic to the subculture plates. When carry-over of the antibiotic was prevented by the addition of beta-lactamase to the nutrient medium, the antibiotics were no longer bactericidal. At a certain antibiotic concentration and at higher concentrations, however, each strain showed a certain survival percentage after 24 h. The tolerance percentage was determined for 15 strains. The values found for the individual strains ranged from less than 0.1 to 11% for cloxacillin and methicillin. since these percentages were reproducible within narrow limits, they could be regarded as a characteristic of the strains. The tolerance percentage was independent of the growth phase of the initial cultures. PMID- 6923715 TI - Apply standards? You do it every day. PMID- 6923717 TI - ANA adopts new federation structure. PMID- 6923716 TI - Sharing decision making with staff. PMID- 6923718 TI - Antimicrobial therapy for surgical patients. AB - The operating room nurse plays a critical role in the administration of antimicrobial therapy for prophylaxis and for treatment. When aminoglycosides are given, the fine line between a therapeutic and toxic dose presents an additional challenge. Timing is equally critical in administering a prophylactic dose of a cephalosporin; too early and it will be ineffective and too late, it may necessitate a full course of treatment rather than the one dose. Armed with the proper knowledge and skills, the operating room nurse will be able to provide the safe competent care that patients receiving antimicrobials should expect. PMID- 6923719 TI - Ambulatory surgery for a penile prosthesis. PMID- 6923720 TI - Scleral buckling for retinal detachment. PMID- 6923721 TI - [Epidemiological study of chronic obstructive bronchopneumopathy in cement workers]. PMID- 6923722 TI - Nursing - in search of a definition. PMID- 6923724 TI - The food factor and the scientific nurse. Food! Glorious food! - and dysnourishment. PMID- 6923723 TI - The nurse and the law: causes in casualty. PMID- 6923725 TI - Anthelmintics: (Part One). PMID- 6923726 TI - Role theory as a model for human interaction: its implications for nursing education. PMID- 6923727 TI - Assessment of nursing care quality. PMID- 6923728 TI - Stress--its effect on registered nurses and patient care. PMID- 6923729 TI - Voluntary euthanasia. PMID- 6923730 TI - RANF through the eyes of a nursing student. PMID- 6923731 TI - Can we guarantee excellence in health care delivery? PMID- 6923732 TI - Redrafted standards for nursing practice. PMID- 6923735 TI - Drugs in current use. Anthelmintics: Part 2. PMID- 6923733 TI - The nurse and the law: community health. PMID- 6923734 TI - The food factor and the scientific nurse: diet and coronary heart disease. PMID- 6923737 TI - An analysis of patient care provided by nursing personnel (a progress report). PMID- 6923736 TI - Babies having babies. PMID- 6923738 TI - Nursing administration in the 80s: the challenge and the satisfaction. PMID- 6923739 TI - Traditional v. tertiary: ideological shifts in nursing education. PMID- 6923740 TI - 'Giant leap forward' begins with the nursing interview. PMID- 6923743 TI - Patient consent. PMID- 6923741 TI - Toxoplasma gondii--an insidious parasite. PMID- 6923742 TI - A 50 years' overview of paediatric nursing practice. PMID- 6923744 TI - Comparative trial of viokase, pancreatin and Pancrease pancrelipase (enteric coated beads) in the treatment of malabsorption in cystic fibrosis. PMID- 6923745 TI - Isolation and partial purification of elastase-released peptide domains that contain the partial activities of pigeon liver fatty acid synthetase. PMID- 6923746 TI - Distribution of complement factors Bf, C2 and C6 in the Western Pacific. AB - Complement components Bf, C2 and C6 have been typed in various Micronesian, Polynesian, Melanesian and Indian populations of the Western Pacific. BfS and BfF gene frequencies are heterogeneous throughout the region but the number of alleles in the Bf system is restricted. C2 is also restricted with the C22 gene frequency from 0-1.3% in all groups except Fijian Indians where it is 4.8%. The C6A and C6B frequencies of Polynesians, Melanesians and Fijian Indians are within the narrow range of frequencies reported for these alleles from other parts of the world. In the Micronesians of Nauru, a third polymorphic allele (C6Nauru) occurs together with a number of rare alleles (C6R). The Nauruan C6 gene frequencies are C6A 44.6%, C6B 45.2%, C6Nauru 6.7% and C6R 3.5% C6Nauri is present in low frequencies in most other Western Pacific populations and C6R variants occur in Polynesians. PMID- 6923748 TI - A possible relationship between human plasma kallikreins I and II. AB - Human plasma kallikrein I (EC 3.4.21.8; Mr 93 000) was found to undergo autolytic cleavage to form a protein resembling kallikrein II (Mr 85 000) plus a small peptide moiety. Conversion was found to be complete upon storage of kallikrein I solution at 4 degrees C for 7 days. PMID- 6923747 TI - Liberation, purification, and properties of thioesterase component of pigeon liver fatty acid synthetase complex. AB - Proteolysis of pigeon liver fatty acid synthetase with elastase results in the quantitative cleavage of the thioesterase component from the enzyme complex. This thioesterase component is two or three times more active catalytically in the isolated state than in the native fatty acid synthetase, and its activity is not affected by the presence or absence of reducing thiols. The proteolytically cleaved thioesterase is separated from the core enzyme in one step by size exclusion chromatography on a Sephadex G-75 column. The peptide obtained by gel permeation is homogeneous with respect to size and charge, as shown by polyacrylamide gel electrophoresis in the presence and absence of SDS. Size exclusion chromatography on Bio-Gel A 0.5 m and Sephadex G-75 columns, sucrose density gradient ultracentrifugation, and N-terminal amino acid analysis also indicate that the proteolytically cleaved thioesterase is homogeneous. The sedimentation coefficient of the thioesterase is approximately 2.9 S. Proteolytic cleavage with elastase also quantitatively releases the [1,3-14C]- or [1,3 3H]diisopropylphosphofluoridate-labeled thioesterase component from the correspondingly labeled fatty acid synthetase. Binding studies with 14C- or 3H labelled diisopropylphosphofluoridate and fatty acid synthetase show that 2 mol of the label are bound per mol of the enzyme when complete loss of fatty acid synthesizing activity occurs. The molecular weight of the thioesterase component is estimated to be 36000 by size-exclusion chromatography, SDS-polyacrylamide gel electrophoresis and amino acid analysis. PMID- 6923749 TI - Ethnographic and secrecy patterns among drug abusers. AB - The underground nature of drug abuse is a major cross-national barrier to the collection of sound epidemiological data. The authors examine some common patterns of secrecy developed by drug abusers to avoid social disapproval or punishment in different socio-cultural settings. Assurances of anonymity and confidentiality may not be sufficient to make the majority of heavy drug abusers "visible" to the researcher. One way to overcome this barrier is to train field staff to recognize certain ethnographic signs i.e. the specific appearance and behaviour of drug abusers that can facilitate identification of target populations. PMID- 6923751 TI - Programme development of drug abuse control in Baluchistan, Pakistan. AB - The drug abuse control programme in Baluchistan is inter-disciplinary and progressive. Its main thrust consists of constant vigilance on border check points by law enforcement agencies, developing in-patient and out-patient facilities for treatment and rehabilitation of addicted persons, and a preventive education programme using the mass media and students from higher educational institutions. PMID- 6923750 TI - Driving under the influence of drugs other than alcohol. AB - This paper illustrates different aspects of the problem of driving under the influence of medicine and is based on a survey carried out in 1976 on three groups of drivers: (a) drivers consuming prescription drugs and alcohol; (b) drivers consuming prescription drugs only; and (c) drivers consuming alcohol only. Traffic accidents and traffic accident risks are approximately equal for all three groups, although the author points out that the frequency of traffic accidents and traffic accident risks involving prescription drug intoxicated drivers is probably larger than indicated by the study, as the sample was drawn from persons suspected of drunken driving. The author recommends epidemiological studies of the problem which would be facilitated if the law permitted blood and urine samples to be taken from any driver stopped on the road. He also suggests that formation of interdisciplinary groups to investigate specific aspects of the problem and closer co-operation between interested countries. PMID- 6923752 TI - Heroin in the Florence area, Italy. AB - The authors report data on the analysis of heroin samples seized in the Florence area between 1975 and the first half of 1981. They consider that the Florentine situation, and the Italian market in general, is different from other non-Italian markets with respect to heroin content and to types of adulterant. No dangerous substances were found in the samples and strychnine, if present, was found in very low concentrations. The concluded that the cause of death in heroin addicts or users is due to the amount of heroin injected (overdose). PMID- 6923754 TI - Health & safety in the workplace--Part 2. Radiation exposure and margins of safety. PMID- 6923755 TI - For nurses only: should nursing administrators use incident reports as a risk management tool? PMID- 6923753 TI - Constituents of Cannabis sativa L., XX: the cannabinoid content of Mexican variants grown in Mexico and in Mississippi, United States of America. PMID- 6923757 TI - The birth of nursing science. PMID- 6923756 TI - These children didn't have to die! PMID- 6923758 TI - Anorexia nervosa: emancipation by emaciation. PMID- 6923760 TI - The myth of individuality. PMID- 6923759 TI - The challenge of treating eating disorders. Part three: in the community. PMID- 6923761 TI - Teaching assertive behavior to psychiatric patients. PMID- 6923762 TI - Reportable deaths. PMID- 6923763 TI - Hickman catheters: your guide to troublefree use. PMID- 6923764 TI - Twelve-hour shifts, a way to beat the "prime time" blues. PMID- 6923765 TI - Whose baby is this? Planned pregnancy--planned birth. PMID- 6923768 TI - Hands-on skills for dealing with hearing aids. PMID- 6923766 TI - What this country needs now...nurses prepared to work with today's parents to revolutionize family-newborn care. PMID- 6923769 TI - Cleaning up the act. PMID- 6923767 TI - A postpartum support service for Halifax mothers. PMID- 6923770 TI - The role of the nurse in the prevention and early detection of malignant melanoma. PMID- 6923772 TI - Primary caregivers; perceptions of nursing behaviors that best meet their needs in a home care hospice setting. PMID- 6923771 TI - Herpes zoster in the immunocompromised patient. PMID- 6923776 TI - Cancer nursing and the law: wrongful life. PMID- 6923773 TI - Sexuality and the male cancer patient. PMID- 6923774 TI - Psychological stress associated with outpatient oncology nursing. PMID- 6923777 TI - Clinical trials--a review of terms and principles--statistical considerations: part II. PMID- 6923775 TI - The sleeping patterns of patients with malignant and nonmalignant diseases. PMID- 6923778 TI - Barriers to patient education in the coronary care unit. PMID- 6923779 TI - Purification and characterization of dog urinary kallikrein. PMID- 6923781 TI - Looking at nurses' training from a counsellor's perspective. PMID- 6923780 TI - The attitude of registered nurses at Addington Hospital towards their profession. PMID- 6923784 TI - Observation of the neurosurgical patient. PMID- 6923785 TI - [Subject didactics as a necessity in nursing training and education: subject didactic components]. PMID- 6923783 TI - The psychological aspects of intensive care units. PMID- 6923782 TI - [Conceptualization in nursing]. PMID- 6923786 TI - The evolution of a profession. PMID- 6923788 TI - The preparation of the nurse in the tuberculosis field. Paper read at the Robert Koch Commemorative Conference on Tuberculosis, 1982. PMID- 6923787 TI - [Subject didactics as a necessity in nursing training and education: community health nursing - subject didactics]. PMID- 6923789 TI - [Personnel development: program planning]. PMID- 6923790 TI - [Clinical studies on pancreatic elastase 1 radioimmunoassay kit (Dainabot)]. PMID- 6923791 TI - The relationship between urinary kallikrein excretion and mineralocorticoids in the rat. PMID- 6923792 TI - [Haemophilus endocarditis. A case of Haemophilus aphrophilus endocarditis in a patient with aortic and mitral valve prosthesis]. PMID- 6923793 TI - Competition: the new solution to health care costs. PMID- 6923796 TI - Nappies: terrys v. disposables. PMID- 6923794 TI - Child health take-over bid by the GPs? PMID- 6923797 TI - Health visiting: a way to get organised. PMID- 6923795 TI - Quality of life: Bard Nursing Award. PMID- 6923798 TI - The American experience: an expanded role. PMID- 6923799 TI - Success through continuing education. PMID- 6923800 TI - Release of proteolytic enzymes from leucocytes attached to IUDs. AB - The leucocytes adhering to intrauterine devices (IUDs) were predominantly mononuclear phagocytic cells (MPCs) and granulocytes. These cells released elastase and a plasminogen activator in the culture medium. The plasminogen activator was found to be immunologically identical to tissue activator, and the release pattern indicated that the activator as well as elastase were released from both MPCs and granulocytes. Thus, the results suggest the generalized conclusion that both MPCs and granulocytes release the tissue activator-type of plasminogen activator. The urokinase-type of plasminogen activator, which was detected initially in some cultures, may originate from endometrial tissue fragments adhering to the IUD. IUDs removed in the end of the menstrual phase and in the midcycle phase released more plasminogen activator than did devices removed at the proliferative and luteal phases. No such cyclic variation was found for the release of elastase. PMID- 6923801 TI - The mega-code system in the critical care unit setting. PMID- 6923803 TI - Wet dressings. PMID- 6923802 TI - Legal update! Professional negligence. PMID- 6923804 TI - Urinary incontinence: CEU study. PMID- 6923805 TI - Buttermilk & yogurt: odor control of open lesions. PMID- 6923807 TI - Structure of the acetylcholine receptor and specificities of antibodies to it in myasthenia gravis. AB - Acetylcholine receptors in skeletal muscle and fish electric organs are intrinsic membrane proteins whose function is to bind acetylcholine released from the nerve ending and trigger the opening of a cation-specific channel in the postsynaptic membrane, thereby facilitating transmission of the nerve signal to the muscle. Investigations from several laboratories indicate that acetylcholine receptors from fish electric organs are composed of four homologous glycoprotein subunits of apparent relative molecular masses (Mr) approximating 40, 50, 57 and 64 x 10(3) designated, respectively, alpha, beta, gamma and delta. These subunits are present in receptor monomers in the mole ratio alpha 2 beta gamma delta. Receptor purified from skeletal muscle appears to have a similar structure. The alpha subunits are unknown. It is known that the cation channel regulated by acetylcholine binding is located within the receptor monomer. Experimental autoimmune myasthenia gravis (EAMG) is induced by immunizing animals with purified receptor. The mechanisms by which neuromuscular transmission is impaired in this model are very similar to those in myasthenia gravis (MG). Although there are many immunogenic determinants on receptors, and EAMG can be induced in rats by any of the denatured subunits, there is a main immunogenic region at which most of the antibodies to native receptors are directed. The main immunogenic region is a conformationally dependent part of the external surface of alpha subunits other than the acetylcholine-binding site or the attached carbohydrate. Antisera from MG patients are also directed primarily at this region. No correlation was detected between the specificities of antibodies to receptor in patients' sera and the severity of their weakness. PMID- 6923806 TI - New uses for old drugs: vasodilators (CEU home study). PMID- 6923809 TI - Insulin receptors and insulin receptor antibodies: structure-function relationships. AB - The insulin receptor has been purified by affinity chromatography and studied by affinity-labelling techniques. It appears to be a disulphide-linked heterotetramer, (alpha beta)2, composed of two copies of a 135,000 Mr subunit (alpha), and two copies of a 90,000 Mr subunit (beta). Beta is readily proteolysed to generate a 45,000 Mr fragment (beta 1). Alpha, beta and beta 1 all contain sialic acid and are, therefore, probably all exposed on the external surface of the membrane. Although alpha is predominantly labelled in affinity labelling studies, beta and beta 1 can also be labelled. Therefore, alpha, beta and beta 1 are all in proximity to the insulin-binding site and may contain part of the binding site. Antibodies have been prepared against the intact, purified receptor and against the isolated alpha subunit. Both antibodies directly interact with the insulin receptor as indicated by their ability to immunoprecipitate the receptor. Neither antibody, however, directly competes with insulin binding. Therefore, they are probably directed against regions of the receptor distinct from the insulin-binding site. In spite of this, these antibodies have a wide range of insulin-like activities. PMID- 6923808 TI - Mechanisms of acetylcholine receptor loss from the neuromuscular junction. AB - At the normal mammalian neuromuscular junction the half-life of the acetylcholine receptor (AChR) ranges from 6 to 13 days (estimates from seven different laboratories). Indirect evidence suggests that the internalized receptor is degraded by a lysosomal mechanism. We have now traced the fate of the AChR labelled in vivo with peroxidase-alpha-bungarotoxin. Segments of junctional folds bearing AChRs are internalized by endocytosis. The endocytosed vesicles are engulfed by tubules and larger vesicles which, by electron cytochemical criteria, represent secondary lysosomes. Pathological mechanisms increased AChR loss from the end-plate. These include destruction of junctional folds, formation of immature junctions with a few or no junctional folds, accelerated internalization of AChR, impaired membrane insertion of new AChR and, possibly decreased AChR synthesis. The common mechanism for destruction of the junctional folds is an altered subsynaptic ionic milieu, and especially focal calcium excess. This can be induced by antibody and complement, too frequent or prolonged openings of the acetylcholine (ACh)-induced ion channel, and other membrane defects. In acquired autoimmune myasthenia gravis there is (a) antibody-dependent complement-mediated lysis of the junctional folds, (b) accelerated internalization of AChR cross linked by antibody and (c) decreased insertion of AChR into the postsynaptic membrane. The last mechanism is attributed to lack of membrane patches available for tight packing and secure anchoring of the receptor. In acute, but not in chronic, experimental autoimmune myasthenia gravis, and infrequently in human myasthenia gravis, macrophages destroy junctional folds opsonized by antibody and C3. In a recently recognized congenital syndrome attributed to a prolonged open time of the ACh-induced ion channel, and to a lesser extent in congenital end plate acetylcholinesterase deficiency, AChR is lost with degradation of junctional folds. In other, less well-defined, congenital syndromes there is deficiency or abnormal function of AChR. This could arise from decreased synthesis or membrane insertion or accelerated degradation of AChR, or from a structurally abnormal AChR with reduced affinity for ACh or with a diminished conductance or open time of its ion channel. PMID- 6923810 TI - Converting micrograms/kilograms/minute to microdrops. 1: Chart vs. formula method. PMID- 6923811 TI - Converting micrograms/kilograms/minute to microdrops. PMID- 6923812 TI - Converting micrograms/kilograms/minute to microdrops. 2. The "key number" conversion method. PMID- 6923813 TI - Converting micrograms/kilograms/minute to microdrops. 3. The "factor of 15" method. PMID- 6923815 TI - Forced dependency in the critically ill. PMID- 6923814 TI - Converting micrograms/kilograms/minute to microdrops. 4. Microdrop calculation for neonates. PMID- 6923816 TI - The rape crisis team: consultation to critical care. PMID- 6923817 TI - Developing a joint practice team. PMID- 6923818 TI - Minimizing stress-of-transfer responses. PMID- 6923819 TI - The DCCN review process. PMID- 6923820 TI - Current approach to SLE and its subsets. PMID- 6923822 TI - Problems of the diabetic foot. Arterial reconstruction: femoral, popliteal tibial, peroneal. PMID- 6923821 TI - Developing an endurance exercise program for the diabetic patient. PMID- 6923823 TI - Noninvasive evaluation of the diabetic extremity (the vascular laboratory). PMID- 6923824 TI - Aorto-iliac disease in diabetes mellitus. PMID- 6923825 TI - The medical management of diabetic patients during surgery. PMID- 6923826 TI - Adolescent diabetes clinic: a specialized treatment approach. PMID- 6923830 TI - A stereospecific mechanism for the aminoacyl-tRNA selection at the ribosome. PMID- 6923828 TI - Advice from the dietitians: adapting recipes for a diabetic meal plan. PMID- 6923827 TI - A diabetes cooking event. PMID- 6923829 TI - Elastolytic activity in the lungs of rats exposed to cadmium aerosolization. PMID- 6923833 TI - [Perioperative short-term prophylaxis with antibiotics in caesarean section]. PMID- 6923831 TI - [Peripartal infections]. AB - Infections are still the most frequent peripartal complications. Very often they are nosocomial (hospital acquired) infections. Diagnosis and therapy of severe conditions may pose considerable problems. The most significant clinical factors in patient survival are the attentive surveillance and early recognition of the patient's disorder. The choice of antibiotics has to be done in consideration of the bacteriology of the vagina (endogenous infection). Removal of the infection site (uterus with or without adnexae) is the therapeutic procedure with the highest success rate in cases with sepsis or bacterial shock. Prophylaxis of infectious morbidity following caesarean section seems to be possible and advisable in patients with certain risk factors (labour, rupture of membranes, repeated vaginal examinations). PMID- 6923832 TI - [The risk of infection to the mother prior, during and after delivery. A registration of nosocomial infections]. AB - During 5 1/2 years all infections arising in the hospital (nosocomial infections) were registered prospectively by an infection control nurse. The incidence of all nosocomial infections in 3192 maternity patients was 2.1%. In 10,569 women following vaginal deliveries 2.6% and in 1,353 women following Caesarean section 21.1%. The commonest infections were urinary tract infections, endometritis, infections of the abdominal wound or the episiotomy, and a phlebitis of the intravenous infusion site. Measures to prevent infection resulted in a steadily decreasing incidence of infections during the 6 years of registration of nosocomial infections. PMID- 6923834 TI - [Antibiotic therapy in bacterial infections in gynaecology]. AB - A brief review of the special aspects concerning the use and selection of chemotherapeutic agents and antibiotics in bacterial infections occurring in gynaecology both specifically and generally. In case of severe bacterial infections such as sepsis it is recommended to combine two antibodies (e.g. beta lactam antibiotics with aminoglycosides or several beta-lactam antibiotics together). Special attention is given to the particularly effective broad spectrum penicillins and cephalosporins as well as to the aminoglycoside antibiotics etc. Individual well-tried antibiotics are briefly characterised in respect of their anti-bacterial efficacy (sensitivity and resistance), their field of application, and their dosage. In particular, the possibilities of the therapy of infections by anaerobic microorganisms and fungi are pointed out. In addition, a brief description is given of antibacterial chemotherapy of pneumonias of urinary tract infections and specifically gynaecological infections (such as adnexitis, endometritis, parametritis, pelveoperitonitis) under the aspects of rational antibiotic treatment. The article includes by pointing out the possibilities of prophylactic administration of antibiotics especially in surgical procedures in the sense of a perioperative short-term prophylaxis. PMID- 6923835 TI - [Case reports of life--threatening infections in the puerperium]. PMID- 6923837 TI - [Amniotic infection syndrome after amniocentesis--a case report]. AB - A severe amniotic infection syndrome with a septic shock and a consumption coagulopathy is reported after an amniocentesis in second trimester. In literature, the risk of an amnionitis after amniocentesis amounts to 0.1%-0.4% and the risk of a severe maternal infection reaches 0.03%-0.19%. The available data show, that the clinical symptoms (rise in temperature, signs of septic shock) start 24-36 hours after the punction. The earlier treatment (evacuation of the uterus or - if necessary - hysterectomy) is accomplished, the more favourable will be the course of the disease with respect to septic shock and DIC. Determination of germs in each amniotic fluid seems to be of prognostic value; thus treatment can be started before infection becomes detrimental for the mother. PMID- 6923838 TI - [Cervico-vaginal flora of patients prior to and following vaginal hysterectomy--a prospective study]. PMID- 6923836 TI - [Nosocomial infections in rooming-in system: results of a two-year study]. AB - Nosocomial infections of 1356 mothers and their newborn have been analyzed and compared in three different regimens for postnatal care of newborn (rooming-in service, mixed service and central newborn nursery). The average nosocomial infection rate of mothers was significantly lower in the rooming-in service as compared to the newborn nursery. Most common nosocomial infections of mothers were urinary tract infections, endometritis, wound infection, enteritis and mastitis; in newborn enteritis, oral candida infections, panaritium, conjunctivitis and staphylococcus skin infections. Staphylococcal infection of newborn were higher in the newborn nursery as compared to the rooming-in service. Epidermic nosocomial infections (e.g. enteritis, candida infections) occurred more often in the newborn nursery as compared to the mixed system and rooming-in service. There was an increased risk of cross infections from mothers with wound infection, endometritis and mastitis to their children. PMID- 6923839 TI - Isolation and properties of an elastase-like proteinase from horse blood leucocytes. AB - The rapid, two steps method of purification of an elastase-like proteinase from cytoplasmic granules of horse leucocytes is described. This enzyme called the proteinase 1 is released easily from isolated granules in the low ionic strength solutions in opposite to the other two molecular forms of which one differs slightly in isoelectric point from the other. The enzyme is a typical neutral proteinase of a broad substrate specificity and wide pH optimum. In a physiological conditions the enzyme is built of two polypeptide chains of molecular weight about 30000 and 20000, respectively. PMID- 6923840 TI - A summer with FNS. PMID- 6923841 TI - Human granulocyte elastase is inhibited by the urinary trypsin inhibitor. AB - Two forms of urinary trypsin inhibitor, A and B, were purified from the urine of pregnant women. Form A was the only inhibitor present in fresh urine and inhibitor B arose from degradation of A upon storage of urine. The molecular masses of A and B were about 44 and 20 kDa, respectively, as judged from dodecyl sulfate polyacrylamide gel electrophoresis, but about 60 kDa and 30 kDa, respectively, as judged from gel filtration analysis. The discrepancy can perhaps be explained by the carbohydrate content amounting to about 10% of each inhibitor. After reduction with mercaptoethanol, inhibitor A and inhibitor B had identical apparent molecular masses of about 20 kDa on dodecyl-sulfate gel electrophoresis. These results and the results of amino acid analysis suggest that one molecule of inhibitor A yields two molecules of inhibitor B. On agarose gel electrophoresis inhibitor A migrated as a rather broad band in the prealbumin region and inhibitor B as 3 well defined bands in the beta-region. Specific antisera were raised against inhibitor A and B. The two inhibitors showed the immunologic reaction of identity with each other and with the plasma inter-alpha trypsin inhibitor, when using either antiserum. The inhibitors both gave quantitative inhibition of bovine trypsin, the results indicating a 4/1 trypsin/inhibitor molar ratio for A and a 2/1 ratio for B. The two substances also effectively inhibited granulocyte elastase. No inhibition of porcine pancreatic elastase was demonstrable. PMID- 6923842 TI - Climbing the career ladder. PMID- 6923843 TI - Negotiating the academic maze. PMID- 6923844 TI - Nursing shortage? Turnover? Maldistribution? PMID- 6923845 TI - The external degree. PMID- 6923846 TI - The doctor of nursing. PMID- 6923848 TI - Sign up! There's a nursing organization to match your needs. ANA: the professional organization. PMID- 6923847 TI - The second step. PMID- 6923849 TI - Sign up! There's a nursing organization to match your needs. NLN: assuring quality in education and service. PMID- 6923850 TI - Infection control: part of the nursing process. PMID- 6923851 TI - Needlestick injuries--a systematic approach. PMID- 6923854 TI - Role of surveillance in the epidemiology of nosocomial infections: overview of measurements in a surveillance program. PMID- 6923852 TI - Infection control in the hospital dental clinic. PMID- 6923853 TI - CDC's guidelines on infection control; more guidelines. PMID- 6923856 TI - Leukopenic care: special nursing considerations. I. Oral care: hygiene measures. PMID- 6923857 TI - Nosocomial data collection, making it meaningful. Part 2: Interfacing infection control with other surveillance systems. PMID- 6923855 TI - Nosocomial data collection: making it meaningful. Part 3: Interfacing infection control with other hospital surveillance systems. PMID- 6923858 TI - [The computer at the service of the patient]. PMID- 6923859 TI - [Notes on nursing education in France]. PMID- 6923861 TI - [The nurse at the heart of the helping relationship: role and function]. PMID- 6923862 TI - [Drug knowledge: baclofen (Lioresal)]. PMID- 6923860 TI - [Application of the concept of "self-image" according to Roy's model]. PMID- 6923863 TI - [Teaching others nursing care at home]. PMID- 6923864 TI - [The extra-mural hospital of New Brunswick]. PMID- 6923865 TI - [The bestiary of health]. PMID- 6923866 TI - [Setting up information systems. Interview by Leo Charbonneau]. PMID- 6923868 TI - [Legal aspects. Nurses, are you listening?]. PMID- 6923867 TI - [An experiment in decentralization]. PMID- 6923870 TI - [AIIC network]. PMID- 6923871 TI - [Roy's adaptation model]. PMID- 6923872 TI - [Suppressing lactation in a safe, comfortable and efficient manner]. PMID- 6923869 TI - [Drug knowledge: zomepirac (sodium) (Zomax)]. PMID- 6923873 TI - [Natural means of birth control]. PMID- 6923875 TI - [AIIC network: accent on genuine communication]. PMID- 6923874 TI - [Doesn't the care record focused on the disorders of the patient carry an element of risk?]. PMID- 6923877 TI - Changing trends in labour relations: effects on collective bargaining for nurses. PMID- 6923876 TI - The ILO's international standards: what they mean for nurses. PMID- 6923878 TI - The role of national nurses associations in socio-economic welfare: Sweden. PMID- 6923879 TI - The role of national nurses associations in socio-economic welfare: Fiji. PMID- 6923880 TI - Protection of nursing practice through collective bargaining. PMID- 6923881 TI - Towards public health. PMID- 6923883 TI - An experiment in intensive dental health education. PMID- 6923882 TI - Problems of the health visitor in the Inner City. PMID- 6923884 TI - Dental decay and its relationship with sugar. PMID- 6923885 TI - Health visitors and dental health education. PMID- 6923886 TI - Dental delights. PMID- 6923888 TI - Elderly people at home--do health and social services reach those most in need? PMID- 6923887 TI - Developing a preventive care service for the elderly. PMID- 6923889 TI - New approaches in health visiting. 2: Caseload profiles--an alternative to the neighbourhood study. PMID- 6923890 TI - [Nutrition education in the maternal health center]. PMID- 6923891 TI - [Social Welfare Board statute book: Social Welfare Board's general guidelines on the diagnosis and prevention of rubella infections]. PMID- 6923893 TI - [When cultures meet]. PMID- 6923892 TI - [Swedish Midwives' Association: compilation of survey replies concerning paracervical block]. PMID- 6923895 TI - Conventional and two-dose amoxycillin treatment of bacteriuria in pregnancy and recurrent bacteriuria: a comparative study. PMID- 6923894 TI - [Scholarship report of a 1982 study trip in western and middle Turkey]. PMID- 6923897 TI - Woman's role in society in the 1980s. PMID- 6923896 TI - Mechanism of surface-mediated activation of bovine factor XII and plasma prekallikrein. PMID- 6923898 TI - Women, ethics, and professionals: a review article. PMID- 6923899 TI - Health care practices, problems, and needs of young adult women. PMID- 6923900 TI - Maldistribution of primary maternal-child health care: mandate for nursing. PMID- 6923901 TI - Northwest coast American Indians' beliefs about childbirth. PMID- 6923905 TI - Age challenges to wound healing. PMID- 6923904 TI - Pressure sores: a deadly nuisance. PMID- 6923906 TI - The aggregate approach: a student experience. PMID- 6923902 TI - Menopause: a survey of attitudes and knowledge. PMID- 6923907 TI - A special report: The World Assembly on Aging. PMID- 6923903 TI - Women helping women with the stress of returning to work. PMID- 6923910 TI - Head injury: a challenging future for neurosurgical nursing. PMID- 6923909 TI - The effect of cholestyramine and Mevinolin on the diurnal cycle of rat hepatic 3 hydroxy-3-methylglutaryl coenzyme A reductase. AB - Rats were fed powdered rat chow or a rat chow diet containing 5% cholestyramine or 5% cholestyramine with Mevinolin (112 mg/100 g food, 200 mg/kg body weight per day). The specific activity of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase was determined at different times during the diurnal cycle of the enzyme. Animals fed cholestyramine had higher specific activities of HMG-CoA reductase at all time points tested when compared to controls. The specific activity at the peak in the diurnal cycle was approximately 8-fold higher in cholestyramine-treated animals. Rats administered the cholestyramine-Mevinolin diet had higher specific activities of the enzyme than either cholestyramine treated or control animals. In the cholestyramine-Mevinolin-treated animals the peak in the diurnal cycle was shifted to D-12 (12th hour of the dark cycle) and the specific activity at this point was approximately 133-fold greater than the basal (L-6) activity in control animals. Optimal conditions for immunotitration studies were determined such that valid conclusions could be drawn from these data. Based on immunotitration experiments, the increased hepatic HMG-CoA reductase activity in cholestyramine-treated animals resulted in part from a 3 fold activation of the enzyme, while the increased specific activity in the cholestyramine-Mevinolin-treated animals was due solely to increased enzyme mass. Hence the administration of Mevinolin blocked the activation of the enzyme induced by feeding cholestyramine alone. This was confirmed by purifying the enzyme to apparent homogeneity from cholestyramine-Mevinolin-treated animals; the specific activity of this enzyme was 4,000-7,700 nmol NADPH oxidized/min per mg protein. Cholestyramine-Mevinolin treatment affords a novel system for generating milligram quantities of rat hepatic HMG-CoA reductase.-Tanaka, R. D., P. A. Edwards, S. Lan, E. M. Knoppel, and A. M. Fogelman. The effect of cholestyramine and Mevinolin on the diurnal cycle of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase. PMID- 6923911 TI - Cognitive dysfunction and social rehabilitation in the severely head-injured patient. PMID- 6923908 TI - C3 convertase of human complement: enhanced formation and stability of the enzyme generated with nickel instead of magnesium. AB - We demonstrate that nickel++ (Ni) can replace Mg in the formation of the C3b,Bb enzyme, and that Ni is more efficient in enzyme formation than Mg. C3b-bearing sheep erythrocytes (EC3b) were used to measure radiolabeled Factor B uptake and C3 convertase activity. Up to nine times more Factor B was specifically bound to EC3b in the presence of Ni than in the presence of Mg under identical conditions. To form one effective hemolytic site (1 Z) per EC3b cell with Ni, three times less Factor B, 12 times less Factor D, and 66 times less metal ion were required than when using Mg. The C3b,Bb formed with Ni (C3b,Bb(Ni)) had a 5 to 10 times longer half-life at different temperatures than the enzyme formed with Mg (C3b,Bb(Mg)). Native properdin stabilized C3b,Bb(Ni) to the same extent as C3b,Bb(Mg) (four to five times) and Factor H accelerated similarly the decay of both enzymes. Ni could also replace Mg in the formation of the C4b,2a enzyme. C4b,2a formation was measured by using C1 and C4b-bearing sheep erythrocytes (EAC1,4b) and native C2. To form 1 Z per EAC1,4b cell with Ni, two times less C2 and 60 times less metal ion were required than when using Mg. The half-life of the C4b,2a formed with Ni was two times longer than that formed with Mg. Decay of both C3b,Bb and C4b,2a enzymes formed either with Mg or with Ni was unaffected by EDTA. These results show that Ni is more efficient than Mg in the generation of both enzymes and suggest that Ni binds to the Mg-binding sites of the enzymes with a higher affinity than Mg. PMID- 6923913 TI - Post concussion syndrome. PMID- 6923912 TI - Auditory evoked responses in acute severe head injury. PMID- 6923914 TI - Clinical correlation of neurogenic pulmonary edema to increased intracranial pressure. PMID- 6923915 TI - Care of ICP monitoring devices: a nursing responsibility. PMID- 6923917 TI - Nursing care of the patient with brain edema. PMID- 6923916 TI - Nutritional assessment of a severely head-injured, multi-trauma patient. PMID- 6923918 TI - Syndrome of inappropriate secretion of antidiuretic hormone. PMID- 6923919 TI - Osteomyelitis of the skull. AB - Osteomyelitis of the skull is a direct infection of the bone. It can be an acute or chronic disease. It usually has an insidious initial onset. Complications can be life-threatening and even fatal. The most frequently associated organism responsible for the disease is Staphylococcus aureus. Tissue specimens must be obtained for definitive culture and sensitivity reports. It is also important that devitalized bone and sequestra be removed as part of adequate therapy. A typical presentation on skull series is a moth-eaten appearance; however, this may not be recognized radiographically for several months. The antibiotic chosen must be given in high enough doses to assure adequate serum levels to eradicate the organism responsible for causing the disease. Length of treatment depends on the clinical course and the extent of infection but may involve several months or longer. Good nursing care is essential in dealing with osteomyelitis and involves preventive as well as therapeutic management. Patient education and support are important aspects of nursing care in helping the patient cope with the disease. PMID- 6923921 TI - Managing human resources. PMID- 6923922 TI - More on clinical ladders. PMID- 6923920 TI - Developing a motivating environment. PMID- 6923923 TI - Expanding the hospital nursing role: an administrative account. AB - In reality, role change among staff RNs is a continuous phenomenon. As medical technology increases, patient care regimes follow suit, and the staff RN is constantly called upon to apply a knowledge base in different ways and to acquire new knowledge and behaviors. The nursing administrator who keeps pace with this growth can capitalize on the phenomenon, guiding the change to see that it is progressive, that it assists the nurse in developing a more advanced nursing (as opposed to mini-physician) identity and that it does improve extant nursing practice. Undertaking a new project of this sort on the unit is likely to create a number of beneficial by-products. For example, nurse-physician rapport and communication increase as each group opens professional boundaries in defining and planning the content of role expansion. The unit's traditional operation must also be examined in the course of building in new functions. System critiques stimulate the unit's nursing manager to weed out less than optimal features of the existing nursing care delivery system. The expanded role has favorably affected nursing care at Mercy Hospital. Physicians, nurses, and most important, the patient have reaped the benefits. The nurse is able to function in a more advanced capacity, and physicians see the benefits to their patients; fewer delays in specific aspects of care delivery with a more sophisticated, higher quality of nursing care. What is exciting about this concept is that the principles could apply to virtually any RN work group that gives direct care to a homogeneous patient population. PMID- 6923924 TI - Ingredients for successful networking. PMID- 6923925 TI - Fostering professional nursing careers in hospitals: the role of staff development, Part 1. PMID- 6923927 TI - The challenge of gerontological nursing. PMID- 6923926 TI - Balance and tissue distribution of vanadium after short-term ingestion of vanadate. AB - Forty-six female Sprague-Dawley rats (170-200 g) were randomly assigned to one of six treatment groups receiving 0.1, 5.0, or 25.0 ppm dietary vanadium with either normal (0.13 mEq/g) or high (1.82 mEq/g) dietary potassium. Supplemental vanadium was administered as sodium metavanadate. These diets were fed for 2 weeks, and all feces and urine collected. At the end of the treatment period, brain, liver, renal cortex and medulla, whole blood, and plasma were obtained and analyzed for vanadium by atomic absorption spectrophotometry, as were the urine and feces samples. Tissue vanadium concentration increased significantly (P less than 0.00001) with increasing food vanadium content, but were not affected by dietary potassium in spite of the polyuria induced in animals on the high potassium diets. The highest vanadium concentrations were found in the renal cortex and the lowest, in the brain. Although urinary vanadium excretion was higher in animals fed the high potassium diets, a relatively small percentage of ingested vanadium was excreted in the urine. Rats fed diets containing no supplemental sodium metavanadate (0.1 ppm vanadium) were in negative vanadium balance, but their growth was not inhibited. Animals receiving 5.0 and 25.0 ppm vanadium diets retained 39.7 +/- 18.5% of ingested vanadium and excreted 59.1 +/- 18.8% of ingested vanadium in the feces. These values indicate greater absorption and retention of ingested vanadium than found In previously reported investigations. PMID- 6923928 TI - Scenario of the future. PMID- 6923929 TI - Nutrition in the elderly. PMID- 6923930 TI - The past as therapy: an experience in an acute setting. PMID- 6923931 TI - In support of nursing homes. PMID- 6923932 TI - Tetracyclines. PMID- 6923933 TI - Psychotropic medications and the nursing process. PMID- 6923934 TI - Behavioral treatment of psychogenic vomiting among children--a review and case example. PMID- 6923935 TI - Consultation and liaison implications of awakening paralyzed during surgery: a syndrome of traumatic neurosis. AB - The traumatic neurotic syndrome that occurs upon awakening paralyzed during surgery is a clinical problem unique to the medical setting. It presents the liaison nurse with potential problems in assessment. Given the patient's hesitancy to discuss the experience, the existence of this syndrome always should be considered when evaluating a highly anxious post-operative patient. Beyond the problems of patient assessment, this syndrome can represent a complex consultation-liaison problem, especially with a staff unfamiliar with its existence. A review of the concepts of consultation-liaison work often identifies problematic areas (such as interdisciplinary cooperation and educational needs) that the consultant should cover. The case presentation and discussion illustrated the process of applying consultation liaison principles to a complex clinical problem unique to the medical setting--the traumatic neurotic syndrome that occurs as a result of awakening paralyzed during surgery. PMID- 6923937 TI - A model for teaching management of disturbed behavior. PMID- 6923936 TI - Developing an outcome audit for a child psychiatric inpatient unit. PMID- 6923939 TI - [High technology and gentleness of midwives: a comment on the "Survey on Maternal and Infant Care at Health Facilities"]. PMID- 6923938 TI - Control of methicillin-resistant Staphylococcus aureus in a burn unit: role of nurse staffing. AB - We investigated retrospectively the spread of methicillin-resistant Staphylococcus aureus (MRS) in a burn unit. During 8 months, 34% of the patients acquired MRS, and transmission continued despite barrier isolation precautions and treatment of colonized personnel with topical intranasal antibiotics. Several findings suggested MRS was spread primarily by contact transmission involving personnel: case-control comparison showed burn size to be the major host risk factor for colonization; correlation analysis of environmental factors revealed a significant (p = 0.001) association of new cases with increased patient load and with staffing by overtime or temporary nurses; and environmental sampling yielded few colonies of MRS. The outbreak halted following implementation of control measures, among which assignment of separate nurses to colonized patients appeared to be essential. The association of different nurse staffing variables with persistence then eradication of MRS suggests nurse staffing may have been an important factor in staphylococcal transmission. PMID- 6923940 TI - [Clear indication of the expected role of the midwife: comments by midwives on the "Survey on Maternal and Infant Care at Health Facilities"]. PMID- 6923941 TI - [No regrets on my past devoted to midwifery: comments by practicing midwives on the "Survey on Maternal and Infant Care at Health Facilities"]. PMID- 6923942 TI - [A starting point in interactions among obstetrics-related professions: comments by obstetricians on the "Survey on Maternal and Infant Care at Health Facilities"]. PMID- 6923944 TI - [Care of a patient facing labor with no preparation for childbirth]. PMID- 6923943 TI - [An experience in assisting in the delivery by a patient with a spinal injury]. PMID- 6923945 TI - [Study on discomforts associated with menstruation]. PMID- 6923947 TI - [Seminar on research. 8. Definition of the cause-effect relationship]. PMID- 6923946 TI - [Study on the route of transmission of Candida]. PMID- 6923948 TI - [Past and the present of customs related to childbirth. 9. Start of individuals: customs related to naming of infants]. PMID- 6923949 TI - [Responding to the needs of today's families: an experiment in out-of-hospital primary maternity care]. PMID- 6923950 TI - [The midwife as a clinician in the antenatal period in England and Wales]. PMID- 6923951 TI - [Mechanism of labor development (3)]. PMID- 6923952 TI - Intra-arterial blood pressure monitoring in the neonate. AB - The advent of intra-arterial pressure monitoring has had a significant impact on the nursing care given in the neonatal intensive care unit. The nurse working in these units must become technically competent in monitoring techniques as well as clinically acute to physiologic measurements and their significance. These skills can be incorporated into planning and providing effective, individualized patient care. Continuous intra-arterial pressure monitoring is an invaluable clinical tool when caring for critically ill neonates. With care, an intra-arterial monitoring system can be easily prepared. This procedure requires minimal nursing time for care and maintenance and is a very safe procedure if appropriate nursing precautions are followed. PMID- 6923953 TI - Community hospital-based obstetrical primary nursing. AB - Just because primary nursing care traditionally has not been offered during the childbearing year does not mean there is no need. Prenatal classes, which were once a rarity, are now well accepted as a necessary and important service to expectant parents. Nurses have a responsibility to document the need for, and illustrate the impact of, nursing interventions. Nursing needs to accept the challenge for the sake of improved patient care. Supporting the expanding family during the crises of the child-bearing year has the potential for improving that family's functioning. The community stands to gain from anything that improves that functioning of the family unit. PMID- 6923956 TI - The psychosocial implications of hysterectomy. AB - The psychosocial impact on the patient having a hysterectomy is of prime concern to the nurse. This impact can dramatically influence the entire course of the surgery. Postoperatively, the physical care needed by the patient can over-shadow the psychosocial implications of the surgery: This must not happen. The psychosocial needs of the patient are an integral part of the care plan for the hysterectomy patient. By incorporating these needs into the plan of care, the nurse will meet the total needs of the patient and help her return to life-force equilibrium. PMID- 6923955 TI - An overview of infertility. PMID- 6923957 TI - Lamaze childbirth education: implications for maternal-infant attachment. PMID- 6923958 TI - Immittance screening for aural problems in school children. AB - The predominant aural health problem in school-age children is middle ear inflammation with effusion. The conventional hearing screening method has ineffectively detected half of those school children with middle ear problems. Acoustic immittance measurements, recently added to the audiologist's battery of tests, effectively and economically screens middle ear effusion. Unfortunately, acoustic immittance does not screen hearing sensitivity as does the conventional pure-tone sweep check. This article describes the principles of acoustic immittance and compares it with pure-tone audiometry; discusses current immittance screening practices; and outlines how acoustic immittance can be included in a school hearing conservation program. PMID- 6923954 TI - Endometriosis. PMID- 6923959 TI - High school students' attitudes toward homosexuality. PMID- 6923960 TI - Are physicians educable? Teaching medical students about school health. AB - Third-year medical students on their pediatric rotation at the University of New Mexico (UNM) are assigned to spend two mornings with school nurses at the students' choice of schools. Each student is given a list of goals and questions relating to those goals to guide his/her experience. Following the two sessions, each student answers a questionnaire testing understanding of aspects of the school nurse's work and interrelationships between school nurses and physicians. Of the first 67 students responding to the questionnaire, 66 found the program valuable and worthy of continuation. The medical students' understanding of the capabilities and limitations of the nurses whose work they observed appeared excellent. Two-thirds of the students perceive poor communication with physicians as a major frustration for the nurses. Their appreciation of this need, plus their ability to recognize the many capabilities of school nurses, should result in better interaction between the two professions. PMID- 6923961 TI - Recidivism and drug use among school-age children. AB - This paper is the result of an investigation of recidivism rates among teenaged children who completed a program designed to improve communication between the children and their parents. A sample of 62 children from 13 to 18 years old was utilized. All had been referred to a mental health program by juvenile courts for therapeutic intervention because of drug offenses. The intervention program stressed family communication and communication techniques and required both the child and parents to attend. Three types of rates of recidivism were then obtained from juvenile court records for each sample member including all referrals, adjusted referrals, (excluding such referrals for truancy, fighting, traffic offenses, etc.), and those referrals for drug offenses only. These were analyzed for both pre- and post- intervention length of time. Analysis of data revealed significant (p v .001) decrease for all three categories of referral. Notable was that the recidivism rate for drug offenses declined significantly. While this data is encouraging some considerations are necessary. First, the degree of experimental control was limited. The use of a control group would perhaps have been beneficial. Secondly, one must consider the effect of the "arrest experience" and its relationship to learning how to avoid getting caught for the same offense twice. This could be examined further if the pre- and post intervention periods could be lengthened. A final consideration would be the effect of other intervention programs on recidivism. since many of the children were receiving more than one type of therapy. The question of which intervention program most effected the decline of recidivism would have to be answered before one could accept the conclusion that the communication program was indeed responsible for the significant decrease in recidivism. PMID- 6923962 TI - A school-based comprehensive health clinic for adolescents. PMID- 6923963 TI - Health education for prospective teachers: is it effective? PMID- 6923964 TI - Psychoactive medication in a large urban school district: reporting methods and results of treatment. PMID- 6923965 TI - Integrating health services and health education: seeking a balance. PMID- 6923966 TI - [Focal point in the evaluation of nursing fees. A discussion]. PMID- 6923967 TI - [Significance of the nursing fee in medical economics]. PMID- 6923970 TI - [Fees for home-visiting nursing]. PMID- 6923968 TI - [The nursing standard and the present status of hospitals]. PMID- 6923969 TI - [Addition of an extra fee for the intensive care in the National Health Insurance System--implementation of the fee standard and future problems]. PMID- 6923971 TI - [Children's process of adaptation to hospitalization--an observation of 6 children ranging from 3 to 6 years of age]. PMID- 6923972 TI - [Man: his new clinical image (10). The body and its expression. (2)]. PMID- 6923973 TI - [Trial preparation of a conference standard for better nursing planning]. PMID- 6923974 TI - [Better patient care through nursing research: progress in the study of patient classification (3)]. PMID- 6923976 TI - [Teaching and objectives in clinical training in adult nursing (2)--clinical instructions in adult nursing]. PMID- 6923975 TI - [Suggestion for basic nursing education (10). Teaching to nurture an active attitude in students--a trial in learning by hypothetical experiences]. PMID- 6923977 TI - [Effects of extracurricular instructions related to classroom teaching- instructions for the 2d year students]. PMID- 6923978 TI - [Nursing education and regional mental health care in Hawaii. (6). Regional mental health services in Hawaii (3)--activities at a halfway house, "The House". Interview by M. Kawano]. PMID- 6923980 TI - The cognitive processes of career Oriented primiparas in identity reformulation. PMID- 6923979 TI - Body related concerns of children with cancer as compared with the concerns of other children. PMID- 6923981 TI - Bruising in healthy 3-year-old children. PMID- 6923982 TI - Recent experience with antimicrobial susceptibility of anaerobic bacteria: increasing resistance to penicillin. AB - Results of antimicrobial susceptibility testing of anaerobes were reviewed for the last 5 years and compared with two previous surveys from this institution. Allowing for differences in methodology, there appears to be a striking increase in penicillin resistance by the "non-fragilis" Bacteroides. Penicillin concentrations of 50 microgram/ml were required to inhibit 70% of 43 strains tested. The clinical implications of this observation are not known, but isolated reports of therapeutic failure when penicillin was used against the non-fragilis Bacteroides have appeared. Penicillin resistance among Clostridium other than C. perfringens was also noted in the current study. Several strains of clindamycin resistant Bacteroides fragilis have been observed during the last 2 years, and whether this represents a true increase in resistance will require close scrutiny of clindamycin susceptibility in the future. Future surveillance of antimicrobial susceptibility of anaerobic bacteria will be useful in the detection of any major changes in susceptibility profiles. This knowledge will potentially affect the choice of antimicrobial agent in patients with serious infections caused by anaerobes. PMID- 6923983 TI - A Martian anthropologist's view of: The Young Doctors. A report of field work done during October, 1981. PMID- 6923984 TI - The nurse's role in disasters. PMID- 6923985 TI - Guidelines for the nursing of patients with methicillin-resistant Staphylococcus aureus. PMID- 6923986 TI - To work or not to work? PMID- 6923987 TI - Report on the development of an innovative clinical assessment test for final year general nursing students. PMID- 6923988 TI - New South Wales government's redistribution and relocation of health services plan: Report no. 2. PMID- 6923989 TI - Nurse educators - God forgive them for they know not what goes on. PMID- 6923991 TI - ACTU child care kit. PMID- 6923990 TI - Nurses in demand. PMID- 6923992 TI - [Chronic suppurative inflammation of the middle ear]. PMID- 6923994 TI - [Role of paramedical personnel in detecting patients with venereal diseases]. PMID- 6923995 TI - [Errors in the drug therapy of malignant tumors]. PMID- 6923993 TI - [Clinical aspects and treatment of acute bronchitis]. PMID- 6923996 TI - [Problems in preserving the health of the elderly]. PMID- 6923997 TI - [Disseminated sclerosis]. PMID- 6923998 TI - [Turpentine baths]. PMID- 6923999 TI - [Potentiation of sombrevin anesthesia]. PMID- 6924000 TI - [Formula for the rapid calculation of the dosage of drug preparations]. PMID- 6924002 TI - [Work of the urology department nurse for gonococcal disease patients]. PMID- 6924001 TI - [Physiotherapy methods in spinal rheumatoid arthritis and osteochondrosis]. PMID- 6924003 TI - [Nurses' work in the consultation polyclinic]. PMID- 6924004 TI - [Nurses' work in the medical treatment office]. PMID- 6924005 TI - [Rules for patients undergoing a course of treatment in physiotherapy offices and departments]. PMID- 6924006 TI - [Syringomyelia]. PMID- 6924007 TI - [Influence of the word]. PMID- 6924008 TI - [Atheistic education of future nurses]. PMID- 6924009 TI - [Retinal periphlebitis]. PMID- 6924010 TI - [Nurse and deontology]. PMID- 6924011 TI - [Diseases of the external auditory canal]. PMID- 6924012 TI - [Anomalous child in the family]. PMID- 6924013 TI - [Timed duodenal intubation by degrees of newborn infants]. PMID- 6924014 TI - [Physiotherapy methods in nocturnal enuresis in children]. PMID- 6924015 TI - [Therapeutic gymnastics in dysplastic scoliosis in children]. PMID- 6924016 TI - [Organization of the resuscitation and intensive therapy ward in a general city hospital]. PMID- 6924017 TI - [Characteristics of the nurses' work in a pediatric oncology department]. PMID- 6924018 TI - [Drug disease]. PMID- 6924019 TI - [Effect of drugs on child behavior]. PMID- 6924020 TI - [Hemorrhagic diathesis]. PMID- 6924021 TI - [Use of mustard plasters]. PMID- 6924023 TI - [Role of the nurse in caring for children suffering from rheumatoid arthritis]. PMID- 6924022 TI - [Psychotherapy problems in the nurse's work]. PMID- 6924024 TI - [Care of the child with pneumonia being treated at home]. PMID- 6924025 TI - [Nurse's care in the rearing and upbringing of the premature child in the family]. PMID- 6924026 TI - [Nutrition of the sick child]. PMID- 6924027 TI - [Why twins are born]. PMID- 6924028 TI - [Causes of acute digestive disorders in young children]. PMID- 6924029 TI - [Health education in conducting mass prophylactic examinations]. PMID- 6924030 TI - [Work of a council of paramedical workers]. PMID- 6924031 TI - [Adaptation of a new group of students]. PMID- 6924032 TI - [Use of problem-oriented instruction in practical exercises]. PMID- 6924034 TI - [Obstructive bronchitis in children]. PMID- 6924033 TI - [Experience in studying in medical school endoscopic methods of examination]. PMID- 6924035 TI - [Infantile cerebral palsy]. PMID- 6924036 TI - [Practical experiences in the treatment of gallbladder diseases]. PMID- 6924037 TI - The politics of fertility. PMID- 6924038 TI - Health education in nursing practice. PMID- 6924039 TI - Problems in adolescence. PMID- 6924040 TI - Preconception care and neural tube defects. PMID- 6924041 TI - When patients ask about the latest and safest oral contraceptive. PMID- 6924042 TI - Joblessness, a chronic debilitating global disease. PMID- 6924044 TI - Changing trends in childrearing. PMID- 6924046 TI - Training for district nurses. PMID- 6924043 TI - Genital infection. PMID- 6924045 TI - Fringe paediatrics. PMID- 6924047 TI - When patients ask about toxic shock syndrome. PMID- 6924048 TI - Sexual problems encountered by health visitors in the course of their work. PMID- 6924049 TI - School nursing--at the crossroads. PMID- 6924050 TI - Human milk banks. PMID- 6924051 TI - Transporting the sick newborn infant. PMID- 6924052 TI - Stoma care without tears. PMID- 6924053 TI - When your patients ask about home pregnancy testing. PMID- 6924055 TI - Medical consequences of unemployment. PMID- 6924054 TI - Management of infant sleeping problems. PMID- 6924057 TI - The future of the school nursing service. PMID- 6924056 TI - The 1981 Education Act: implications for nursing. PMID- 6924058 TI - When your patients ask about the dangers of salt. PMID- 6924059 TI - Present day management of diarrhoea and vomiting. PMID- 6924060 TI - Nurses and global issues. PMID- 6924061 TI - Communications between pregnant women and their medical and midwifery attendants. PMID- 6924062 TI - Longer visiting hours. PMID- 6924063 TI - Infant feeding for the 1980s. PMID- 6924064 TI - Pregnant at work. PMID- 6924066 TI - Planning operating departments No. 5. The principles of commissioning. PMID- 6924065 TI - Treatment of methicillin-resistant Staphylococcus aureus infections. PMID- 6924067 TI - British Heart Foundation. PMID- 6924068 TI - Intracranial pressure monitoring. PMID- 6924070 TI - How the infection control nurse can help the theatre nurse. PMID- 6924069 TI - First competition--first prize. PMID- 6924071 TI - Recombination between dispersed serine tRNA genes in Schizosaccharomyces pombe. PMID- 6924072 TI - Isolation of a mouse pseudo tRNA gene encoding CCA--a possible example of reverse flow of genetic information. PMID- 6924073 TI - Modulation of complement by autoimmune antibodies isolated from sera of patients with membranoproliferative glomerulonephritis and systemic lupus erythematosus. PMID- 6924074 TI - Nursing care of the diabetic patient with renal disease. PMID- 6924075 TI - Support systems as a factor in hemodialysis. PMID- 6924076 TI - A comparison of clearances obtained with manual and cycling peritoneal dialysis. PMID- 6924077 TI - NATCO--an organization dedicated to serve those with end stage organ failure. PMID- 6924079 TI - Some thoughts on perception. PMID- 6924078 TI - Standards of care for the CAPD patient. PMID- 6924080 TI - Administering medications on hemodialysis. PMID- 6924081 TI - Not only for rich...tax sheltered investments offer help for average people. PMID- 6924082 TI - Communication: the key to improved patient understanding. PMID- 6924083 TI - Patient emotional response to intravenous therapy. PMID- 6924084 TI - Metamorphosis. PMID- 6924086 TI - Responding to a need: home intravenous therapy. PMID- 6924087 TI - Use of a transparent polyurethane dressing for peripheral intravenous catheter care. PMID- 6924085 TI - Infusion thrombophlebitis and infiltration associated with intravenous cannulae: a controlled study comparing three different cannula types. PMID- 6924090 TI - Test your knowledge of adult health problems. Part 1. PMID- 6924088 TI - Making the NITA standards work for you. PMID- 6924092 TI - When the giver is a receiver. Sharing. PMID- 6924091 TI - Deciphering diagnostic studies: serum bilirubin. PMID- 6924089 TI - Managing special patients' fluids and electrolytes. PMID- 6924094 TI - Mr. J.J. Sylvester was a real con artist. PMID- 6924093 TI - EAB: a new route for vascular rehabilitation. PMID- 6924095 TI - Getting the most from patient interviews. PMID- 6924096 TI - Your patient with pneumothorax: a patient in distress. PMID- 6924099 TI - Understanding urinary tract infection in women: the first step to controlling it. PMID- 6924097 TI - An easy recipe for assessing your patient's nutrition. PMID- 6924098 TI - Probing the ins and outs of congestive heart failure. Earn CEU's. PMID- 6924101 TI - How to call an ambulance. PMID- 6924100 TI - Emergency! First aid for fractures. PMID- 6924103 TI - Motivating children to become assertive health care consumers. PMID- 6924104 TI - Health care today. PMID- 6924105 TI - What to do when the doctor's wrong. PMID- 6924107 TI - Your image; it's more important than you think. PMID- 6924106 TI - Patient teaching: keys to more success more often. PMID- 6924108 TI - Hospital closed: surviving hospital bankruptcy. PMID- 6924109 TI - How to control anger--your own and others'. PMID- 6924110 TI - Want some good advice? Think twice about being a patient advocate. PMID- 6924111 TI - Communication tips: don't believe everything you hear. PMID- 6924112 TI - Court case: is the hospital responsible for employee safety? PMID- 6924113 TI - [The law for the protection of young people]. PMID- 6924115 TI - [Nurse wanted...40 years of experience]. PMID- 6924114 TI - [Plea for the hospitalized child]. PMID- 6924117 TI - [Beneficiaries' ombudsman]. PMID- 6924116 TI - [Hyperactivity in children: its' causes]. PMID- 6924118 TI - [The pregnant worker is exposed to multiple little-known hazards]. PMID- 6924119 TI - [Communication and helping relationship, elements of nursing competence (3)]. PMID- 6924120 TI - [The last childhood or Alzheimer's disease]. PMID- 6924122 TI - [Thalassemia: a disease afflicting mainly Greeks and Italians]. PMID- 6924123 TI - [Use of tobacco and illegal substances in adolescents. Prospective nursing interventions]. PMID- 6924121 TI - [A solution to polypharmacy: the drug consumption profile]. PMID- 6924124 TI - [Night work]. PMID- 6924127 TI - [The refusal to provide care without sufficient reason]. PMID- 6924125 TI - [Researchers from Quebec score points in the campaign against cancer]. PMID- 6924126 TI - [Are health problems of working women due to the environment or to their "femininity"?]. PMID- 6924128 TI - The Janus-faced literatures on primary nursing. PMID- 6924129 TI - Profile: black deans of nursing programs. PMID- 6924130 TI - Management simulation: baccalaureate style. PMID- 6924131 TI - Educating nursing's leaders: agenda for action. PMID- 6924132 TI - Satisfaction and stress incidents reported by hospice nurses: a pilot study. PMID- 6924134 TI - Moving patients easily. PMID- 6924133 TI - Island nursing services for Shetland. PMID- 6924135 TI - More consultants - at what costs? PMID- 6924137 TI - The management of clinical specialties - 7. The coronary care unit - 2. PMID- 6924138 TI - What is a nurse really worth? PMID- 6924136 TI - Primary health care - a case for teamwork. PMID- 6924139 TI - Caring for confused elderly people. An experimental support service. PMID- 6924140 TI - A changing nurse in a changing society. PMID- 6924142 TI - Legal notes: dismissal in connection with a strike or other industrial action. PMID- 6924141 TI - The management of clinical specialties--8. Management in stoma care. PMID- 6924143 TI - The sharp end of caring. PMID- 6924144 TI - The need for unity. PMID- 6924145 TI - Cheadle Royal--a hospital of contrasts. PMID- 6924146 TI - An overview of psychiatry now. PMID- 6924147 TI - Supportive care in the community. PMID- 6924148 TI - Power--getting a piece of the action. PMID- 6924151 TI - Standardized nursing care plans. PMID- 6924150 TI - Performance appraisal. PMID- 6924149 TI - The power problem. PMID- 6924152 TI - Care of the comatose: complex problems faced alone. PMID- 6924153 TI - Nurses participation in bargaining units. PMID- 6924154 TI - Law for the nurse manager: nursing students as litigators. PMID- 6924155 TI - Balancing priorities to attain quality care. PMID- 6924157 TI - Art & science of management. Raising their sights. PMID- 6924158 TI - Focus: on games people play in hospitals. PMID- 6924160 TI - Comparing classification systems. PMID- 6924156 TI - Informed consent rights, responsibilities and roles. PMID- 6924159 TI - Write where you work. PMID- 6924162 TI - Administrative turnover. PMID- 6924161 TI - A CPR team: the answer to chaotic codes. PMID- 6924164 TI - Art and science of management: tactics of persuasion. PMID- 6924166 TI - Save the new graduate. PMID- 6924165 TI - Law for the nurse manager: liability for infection control. PMID- 6924167 TI - The art of effective communication. PMID- 6924163 TI - Senate bill 666. PMID- 6924169 TI - Nurses and physicians: of gnats and humbugs. PMID- 6924168 TI - The economic importance of nurses. PMID- 6924170 TI - What motivation isn't. PMID- 6924171 TI - The procedure book: a monstrous problem. PMID- 6924172 TI - Art and science of management: maintaining discipline. PMID- 6924173 TI - Teaching modules. PMID- 6924174 TI - Drug abuse among nurses. PMID- 6924175 TI - Synthesis of an inquiry: CICIAMS and primary health care. PMID- 6924176 TI - [10 years of Catholic Church contributions to the reorganization of medical activities in Zaire - 1971-1980]. PMID- 6924177 TI - "Dedication". CICIAMS' 12th World Congress. PMID- 6924178 TI - [Responsibility for quality care]. PMID- 6924180 TI - [Professional integrity and medicomoral code]. PMID- 6924181 TI - CICIAMS XII World Congress. PMID- 6924184 TI - [CICIAMS' survey on primary health care. Report of the International Technical Committee]. PMID- 6924185 TI - W.H.O. study shows "brain drain" responsibility of both "recipient" and "donor" countries. PMID- 6924183 TI - Keynote address of Hon. Enrique Garcia, Minister of Health. PMID- 6924179 TI - Concern; the mandate of the Christian nurse. PMID- 6924182 TI - Development and future of CICIAMS in Asia. PMID- 6924186 TI - [Care to the aged. CICIAMS' opinion presented at the occasion of the conference organized by the European Bureau of WHO; Cologne 16-19 Nov. 1981]. PMID- 6924187 TI - [C.I.C.I.A.M.S.' European seminar in Strasbourg. Introduction: health care, human rights]. PMID- 6924188 TI - C.I.C.I.A.M.S. European seminar in Strasbourg. Opening address: health care as a human right, primary health care as a solution. PMID- 6924189 TI - Solvent abuse--a growing problem. PMID- 6924190 TI - More effective control of pesticides. PMID- 6924191 TI - Working as a rig medic. PMID- 6924193 TI - Safety: setting standards for airborne contaminants. PMID- 6924192 TI - Work stress and its effect on wives. PMID- 6924195 TI - Risk appraisal and its effect on lifestyle. PMID- 6924197 TI - Toxicology of industrial metals--inorganic lead. PMID- 6924198 TI - A pilot occupational health screening program provided by baccalaureate nursing students. PMID- 6924194 TI - Primary and secondary prevention of substance abuse in nurses. PMID- 6924196 TI - Holistic health, human ecology, and you. PMID- 6924199 TI - The breast-feeding worker--risk or benefit? PMID- 6924201 TI - Institutional licensure: a revitalized concept. PMID- 6924200 TI - Wellness at work: a seven-step "dollars and sense" approach. PMID- 6924202 TI - Sexuality: a variable in the nurse/client relationship. PMID- 6924203 TI - Surfactant supplementation in the preterm rabbit: effects of applied volume on compliance and survival. AB - Preterm rabbit neonates, delivered on the 27th day of gestation, were treated before the first breath with a tracheal instillation of ESA, a suspension of lipids extracted from pulmonary surfactant. Lung compliance development and neonatal survival were studied after treatment to determine the effect of suspension volume and concentration. Compliance development was not dependent on either delivery volume or suspension concentration, but rather on the quantity of phospholipids instilled. Indices of improved expansion and stability demonstrated a dose response relationship up to 1.1 mg phospholipid per g lung. Larger doses neither improved nor detracted from the response. The ability of the neonates to survive and adapt to an air breathing environment was influenced by the instillation volume. Viability was reduced when the treatment volume exceeded 16% of the functional residual capacity. Prophylactic surfactant supplementation therapy may be useful in preventing the development of neonatal respiratory distress syndrome. Surfactant extract may prove acceptable for both prophylaxis and treatment of established respiratory distress syndrome. PMID- 6924204 TI - Competencies of graduates of nursing programs. Report of the NLN Task Force on competencies of graduates of nursing programs. PMID- 6924205 TI - Cost of nursing education. A manual for analysis of expenditures. Part I. Method, directions, and examples. PMID- 6924206 TI - Cost of nursing education. A manual for analysis of expenditures. Part I. Method, directions, and examples. Associate degree program. PMID- 6924207 TI - Scholarships, fellowships, traineeships, and loans for registered nurses. PMID- 6924208 TI - Scholarships and loans for beginning education in nursing. PMID- 6924211 TI - A nursing research committee within an acute care setting: its inception and development. PMID- 6924210 TI - [Development of a scale of postoperative recovery]. PMID- 6924209 TI - The minimum intragenic sequences required for promotion of eukaryotic tRNA gene transcription. AB - Transcription of eukaryotic tRNA genes is controlled by two intragenic regions, the D-control region (which in the tRNA codes for the D-stem and -loop) and the T control region (which in the tRNA codes for the T psi C loop). To determine whether these sequences alone are sufficient to promote tRNA gene transcription in vitro, the two control regions of a Drosophila tRNAArg gene were cloned separately from the context of the parental DNA (these constructions are called tRNA minigenes). The tRNA minigene that contains both intragenic control regions supports in vitro RNA synthesis in Xenopus laevis oocyte and HeLa cell transcription systems. The mutant which has deletions to nucleotide 7 within the mature tRNA coding region, pArg5.7, and minigenes derived from it do not support RNA synthesis in a Drosophila Kc cell transcription system. Xenopus and Hela extracts transcribe pArg5.7 albeit at reduced levels compared to the wild-type gene. The tRNA minigene that contained only the D-control region was not able to support RNA synthesis in any of these three transcription systems. A mutant tRNA gene comprising the 3' half of the tRNAArg gene similarly was not able to support RNA synthesis. These experiments show that the DNA sequence from nucleotides 7 58, which contains both intragenic control regions of the tRNA gene, possesses sufficient information to initiate specific transcription by RNA polymerase III in Xenopus and HeLa systems. The transcription efficiency of this tRNA minigene however is reduced to about 20% the transcription level of the wild type tRNA gene. This lowered level of transcriptional efficiency results from deleting the ends of the native tRNA gene and its adjacent flanking sequences. The affects of deleting 5' sequences are most pronounced in the Drosophila transcription system. PMID- 6924212 TI - Duration experience: a useful theoretical construct for nursing therapy and research. PMID- 6924214 TI - A developmental perspective on the nursing diagnosis of fear and anxiety. PMID- 6924213 TI - Interdisciplinary education: idealism and realism. PMID- 6924216 TI - Three phases of father involvement in pregnancy. AB - A field study focusing on men's experiences of first-time expectant fatherhood, including intensive interviews with 20 expectant couples, short field interviews with 80 additional fathers, participant observation in prenatal classes and clinics, and content analysis of popular literature was conducted for the purpose of description and generation of substantive theory. Interview and field data were analyzed using constant comparative analytic technique for qualitative data. Evidence suggest a characteristic pattern of development of subjective emotional involvement in pregnancy among first-time expectant fathers. This pattern consists of three phases: an announcement phase, a moratorium and a focusing phase. The length of the second phase appears to be related to the man's perception of his own readiness for pregnancy. The father's speed of progression though these phases may affect later adjustment to fatherhood. Further testing and validation of these findings is indicated. PMID- 6924215 TI - Nursing procedures and alterations in transcutaneous oxygen tension in premature infants. AB - This study evaluated the effects of three routine nursing procedures--suctioning, repositioning, and performing a heelstick--on blood oxygen levels in premature infants, using a transcutaneous oxygen (Tcp02) monitor. Twenty-five infants with respiratory distress syndrome were monitored for three hours during which all three procedures were performed. Continuous Tcp02 records were used for measurement of baseline Tcp02 degree and duration of Tcp02 changes, length of procedural time, and rest time prior to procedures. Data were analyzed to determine if Tcp02 was altered during routine procedures, and if the degree of change was affected by length of procedure or length of rest prior to a procedure. Degree of Tcp02 change was analyzed in relation to length of time taken to recover from procedures. Tcp02 was decreased significantly during suctioning and repositioning but not during heelstick. The three procedures resulted in different degrees of change in Tcp02. Suctioning elicited the greatest decrease, followed by respositioning then heelstick. Recovery time was related to the degree of change in Tcp02 only after the repositioning procedure. Length of procedure and rest time did not relate to the degree of change in Tcp02, suggesting that it was the type of procedure that determined infant response. PMID- 6924217 TI - The relationship of self-disclosure, interpersonal dependency, and life changes to loneliness in young adults. AB - Using a sample of 209 volunteer students between the ages of 18 and 25 from an urban university, the relationships between self-disclosure, interpersonal dependency, life changes, and loneliness were studied. Respondents completed the Jourard 40-Item Self-Disclosure Questionnaire, the Interpersonal Dependency Inventory, the Recent Life Change Questionnaire, and the revised UCLA Loneliness Scale. Pearson product-moment correlation coefficients and multiple regression analysis were used to test the hypotheses. Hypotheses were supported predicting an inverse relationship between self-disclosure and loneliness (p less than .005) and a positive relationship between interpersonal dependency and loneliness (p less than .005). However, a positive relationship between life changes and loneliness was not supported. Data also supported the hypothesis that self disclosure, interpersonal dependency, and life changes would account for greater variance in loneliness than any single variable alone (F(3,204 = 14.433), p less than .01). From a stepwise multiple regression analysis, self-disclosure and interpersonal dependency together accounted for 17.4 percent of the variance in loneliness. Implications for nursing practice are discussed with particular emphasis on potential strategies for preventing loneliness. PMID- 6924218 TI - The validity of health risk appraisal. PMID- 6924219 TI - Knowledge and beliefs about breast cancer and breast self-examination among athletic and nonathletic women. AB - Women' knowledge of breast cancer and their beliefs about susceptibility to breast cancer and benefits of breast self-examination were explored in relation to frequency of practice of breast self-examination. Previous findings indicated that knowledge and beliefs may affect the practice of preventive health behaviors. A self-report questionnaire was administered to 263 women contacted through sorority alumnae groups and Y.M.C.A. groups. Subjects were grouped according to levels of physical exercise (high, moderate, or none) and compared on knowledge and beliefs about breast cancer and breast self-examination (BSE) and practice of BSE. Data were analyzed using descriptive statistics and chi square analysis. Results showed women overestimated the prevalence of breast cancer but were correctly aware that most lumps are not malignant. They generally were uninformed of the risk factors of breast cancer, except for a positive family history of breast cancer. The majority perceived themselves as strongly susceptible to breast cancer and almost all perceived BSE as beneficial in reducing the threat of death from breast cancer. Only 37 percent of the women practiced breast self-examination regularly. No significant relationship existed between knowledge or beliefs and frequency of performance of BSE. Nor were there any significant differences in frequency of practice between the exercisers and nonexercisers. It may be concluded from this study that knowledge of breast cancer, beliefs about breast cancer and breast self-examination or engaging in regular physical exercise as a preventive health behavior do not affect the practice of breast self-examination. PMID- 6924221 TI - The world of nursing on prime time television, 1950 to 1980. AB - This study reported the results of a content analysis of prime-time television portrayals of nurses and nursing over the past three decades with attention to scope of nursing practice, career orientation of nurses, nursing actions, and nurses' impact on patient welfare. The sample was 320 episodes from 28 series. The findings showed that nurses were depicted as working in acute care settings, entering nursing for altruistic reasons, predominantly acting as a resource to other health professionals, not using problem-solving and evaluation skills, deficient in administrative abilities, and remiss in providing physical comforting, engaging in expanded role activities, patient education and scholarly endeavors. Since the 1960s the trend in the quality of nurse portrayals has been downward. This has created a current crisis in communicating the world of nursing to the public via the most powerful form of mass communication, television. PMID- 6924223 TI - Temperature measurement in a clinical setting. PMID- 6924222 TI - The effect of nursing care modalities and shift assignments on nurses' work experiences and job attitudes. PMID- 6924220 TI - Cool and heated aerosol and the measurement of oral temperature. AB - This study investigated the establishment of a data base for use when assessing body temperature in patients receiving aerosol therapy by face mask. Thirty subjects participated in two different treatment situations. Baseline temperature recordings were taken while subjects had heated aerosol administered through a standard face mask. Temperature recordings were repeated at one-minute and five minute intervals after the mask was removed. Temperature recordings were repeated using cool aerosol treatments. An electronic thermometer was used for sublingual temperature recordings, and a polygraph with preamplifier and thermocouple interface was used to record changes in air temperature at the portal entry of the face mask. Constant monitoring of controlled ranges of aerosol temperature at the portal entry site allowed comparison of data during treatment. Significant effects were reported for both the cool and heated aerosol treatments. A comparison of mean baseline temperature with temperatures obtained at the measurement intervals yielded no change greater than three-tenths degree centigrade. This investigation suggested that a statistically significant change in oral temperature with treatments took place but there is relatively little clinically significant change in oral temperature due to aerosol temperature's influence. PMID- 6924225 TI - Time series analysis: an alternative for nursing. PMID- 6924224 TI - Reasons nurses participate in self-study continuing education programs. PMID- 6924227 TI - A drink problem. PMID- 6924226 TI - A different accent on care. PMID- 6924231 TI - The epidemiology of epilepsy. PMID- 6924229 TI - Community care study: glioma. PMID- 6924230 TI - Inside the outpatient department. PMID- 6924232 TI - Nurses and the dysphasic patient - lost for words. PMID- 6924237 TI - Nurses at war. Interview by Laurence Dopson. PMID- 6924233 TI - Control of body rocking in a mentally handicapped boy. PMID- 6924235 TI - Wound care No. 14. Wounds seen in the accident and emergency department. PMID- 6924234 TI - Guidelines for studying and working abroad. 1. How to plan a study visit. PMID- 6924236 TI - A (muted) vote of confidence. PMID- 6924238 TI - Your profession needs you: determining our destiny. PMID- 6924240 TI - Nursing care study: pregnancy complicated by renal failure. PMID- 6924239 TI - Your profession needs you: combining the voices in the profession. PMID- 6924241 TI - Quality assurance audit for the nursing process. PMID- 6924242 TI - A new concept in airway care. PMID- 6924245 TI - A self-administration system for elderly patients at Highbury Hospital. PMID- 6924243 TI - Social skills training. PMID- 6924244 TI - Recovery from hysterectomy. PMID- 6924246 TI - Nursing - the caring profession. Could you care more? PMID- 6924228 TI - Breakdown: commonsense psychiatry for nurses. 1. Alcoholism. PMID- 6924248 TI - Guidelines for studying and working abroad. 2. General information. PMID- 6924247 TI - Nurse Smith's notes: understanding drug treatment. 3. PMID- 6924249 TI - Back to basics. PMID- 6924250 TI - The nurse practitioner at work. 1. Primary care. PMID- 6924251 TI - Under new management. PMID- 6924254 TI - The use of seclusion. PMID- 6924253 TI - Use of the laser in gynaecology. PMID- 6924252 TI - Oedema. PMID- 6924256 TI - Adding life to years. PMID- 6924255 TI - Fools rush in? Or back to nursing. PMID- 6924257 TI - Abortion in today's world. PMID- 6924258 TI - Body mechanics. PMID- 6924259 TI - Is this the death of the NHS? PMID- 6924260 TI - The art of observation. 10. Mother and child bonding. PMID- 6924261 TI - Geriatric wards: would you eat here? PMID- 6924262 TI - Herbal healing: every witch way. PMID- 6924263 TI - Legislation: the legal route to life. PMID- 6924264 TI - Deep vein thrombosis. PMID- 6924265 TI - Think before you act. PMID- 6924266 TI - Psychiatry/mental handicap forum 10: education. Sweep away the tidy boxes. PMID- 6924267 TI - Psychiatry/mental handicap forum 10: education. Something to offer. PMID- 6924269 TI - One day you will understand. PMID- 6924270 TI - Health education. Breast cancer: facts and fallacies. PMID- 6924268 TI - Survival kit for managers: 4. Lies, damned lies and statistics. PMID- 6924271 TI - Institutionalisation: a change of mind. PMID- 6924272 TI - Exams: third time unlucky. PMID- 6924274 TI - Anytown anecdotes: no time for love. PMID- 6924273 TI - Nursing care study: little boy blue. PMID- 6924275 TI - Attitudes: exploring the world of research. PMID- 6924276 TI - Controversy: life is not a therapeutic exercise. PMID- 6924277 TI - Peritoneal dialysis: a cycler made for one. PMID- 6924278 TI - Careers: the clinical teacher. PMID- 6924279 TI - The art of observation. 11. Beauty is but skin deep. PMID- 6924281 TI - Health visiting: don't sit on the political fence. PMID- 6924282 TI - Health visiting: the human cost of unemployment. PMID- 6924280 TI - Suicide: death wish. PMID- 6924283 TI - Health visiting: housing and health. PMID- 6924284 TI - Health visiting: supporting role. PMID- 6924286 TI - Midwifery: the de-skilling of childbirth. PMID- 6924285 TI - Just food for a rainy day? PMID- 6924288 TI - Nursing posts: quantifying the management grades. PMID- 6924289 TI - Issues in nursing. 11. Onwards from Platt. PMID- 6924287 TI - Survival kit for managers. 5. Manpower planning: let the problems guide your thinking. PMID- 6924290 TI - A two-way process. PMID- 6924291 TI - Bereavement: mothers and babies in limbo. PMID- 6924292 TI - Nursing in Europe: continental drift. PMID- 6924293 TI - Nursing care study: reluctant to recover. PMID- 6924294 TI - Careers: accident and emergency nursing. PMID- 6924295 TI - Unemployment among newly qualified nurses. PMID- 6924296 TI - Profile: Sheila Quinn. A well-deserved accolade. Interview by Tamara Ross. PMID- 6924297 TI - Hypothyroidism. PMID- 6924298 TI - The art of observation. 12. Duty for goodness sake? PMID- 6924299 TI - Clinical forum 11. Iatrogenic disorders in the elderly. Do they really need all those drugs? PMID- 6924301 TI - Clinical forum 11. Iatrogenic disorders in the elderly. A prescribing dilemma. PMID- 6924300 TI - Clinical forum 11. Iatrogenic disorders in the elderly. Drugs in the later years of life. PMID- 6924302 TI - Clinical forum 11. Iatrogenic disorders in the elderly. Drug interactions. PMID- 6924304 TI - Health care in China: East meets West. PMID- 6924305 TI - Survival kit for managers. 6. Recruitment and selection. PMID- 6924303 TI - Clinical forum 11. Iatrogenic disorders in the elderly. Why don't they comply? PMID- 6924308 TI - The odds are against nurse tutors. PMID- 6924307 TI - Anytown anecdotes: you're never too old for appendicitis. PMID- 6924306 TI - Pacemakers: feverish activity at Fazakerley. PMID- 6924309 TI - Voluntary help: an untapped source of expertise. PMID- 6924310 TI - Reorganisation: the way forward. PMID- 6924316 TI - Education forum. 7. Progress by degrees. PMID- 6924311 TI - School nurses: head hunting. PMID- 6924312 TI - Careers: nursing the elderly. PMID- 6924315 TI - Community support for the elderly: crossing the road to confidence. PMID- 6924313 TI - Nursing behind the Iron Curtain. PMID- 6924318 TI - Eye surgery: zooming in on lenses. PMID- 6924317 TI - Education forum. 7. The poor relations. PMID- 6924314 TI - Indeterminate sex. PMID- 6924319 TI - Eye research: screening for visual diseases. PMID- 6924320 TI - Pacemakers: coping with paralysis. PMID- 6924321 TI - Standards of behaviour. PMID- 6924323 TI - Whooping cough: time to exercise control; let off lightly. PMID- 6924322 TI - Survival kit for managers. 7. The shortlist and interview. PMID- 6924324 TI - The art of observation. 13. A reflection on poverty. PMID- 6924325 TI - Just like Topsy, the job grew. PMID- 6924326 TI - Education in the classroom: practice without pressure. PMID- 6924327 TI - Pay dispute: morning after the day before. PMID- 6924329 TI - Whitley Council v review board? PMID- 6924328 TI - Careers: community neonatal nursing. PMID- 6924330 TI - The art of observation. 14. Show a bit of sympathy. PMID- 6924331 TI - Offshore nursing: on metal islands in the sea. PMID- 6924332 TI - Offshore nursing: offshore-hospital. PMID- 6924333 TI - Contact dermatitis. PMID- 6924335 TI - Ethics: three aspects to the job. PMID- 6924334 TI - Antenatal clinics. 1. Where have we gone wrong? PMID- 6924336 TI - Community forum. 11: District nursing. Men in a woman's world. PMID- 6924337 TI - Community forum. 11. District nursing. For safety's sake. PMID- 6924338 TI - From the cradle to the grave. PMID- 6924339 TI - Multiple sclerosis: the nursing auxiliary's caring role. PMID- 6924341 TI - Life begins at 88. PMID- 6924342 TI - Survival kit for managers. 8. Staff appraisal and development. PMID- 6924340 TI - Pacemakers: laughter on the ward. PMID- 6924344 TI - The day trip: Southend or bust. PMID- 6924343 TI - No need to communicate. PMID- 6924346 TI - Nursing care study: home is where the heart is. PMID- 6924347 TI - Mental handicap: active analysis. PMID- 6924345 TI - Anytown anecdotes: battling against mother's advice. PMID- 6924348 TI - The other side of the thermometer. PMID- 6924349 TI - Careers: child development. PMID- 6924350 TI - When crying doesn't help. PMID- 6924351 TI - Malignant melanoma. PMID- 6924352 TI - The art of observation. 15. Her last desperate act. PMID- 6924353 TI - Law. 1. From day one to retirement. PMID- 6924354 TI - Psychiatry/mental handicap forum. 11. When the family must change too. PMID- 6924355 TI - Issues in nursing. 12. Links across the seas. PMID- 6924357 TI - Antenatal clinics. 2. Get off the conveyor belt. PMID- 6924356 TI - International issues in nursing. 12. A healthier life for all. PMID- 6924358 TI - Survival kit for managers. 9. Labour relations and discipline. PMID- 6924359 TI - Alcoholism: on the rocks. PMID- 6924360 TI - Nursing care study: a legacy of disease. PMID- 6924361 TI - In the end, we all lost. PMID- 6924364 TI - The listening, liaising, counselling HV. PMID- 6924365 TI - Premenstrual tension: Friern Barnet in one. PMID- 6924363 TI - Pacemakers: home sweet hospital. PMID- 6924362 TI - The four dimensional nurse. PMID- 6924366 TI - Oral hypoglycaemics. PMID- 6924367 TI - Careers: missionary nursing. PMID- 6924369 TI - An elastase inhibitor from isolated bovine pulmonary macrophages. PMID- 6924368 TI - Antibiotic-resistant pneumococci. PMID- 6924370 TI - [Health of infants and schoolchildren]. PMID- 6924371 TI - [In the children's ward]. PMID- 6924372 TI - [Current directions in controlling neoplastic disease in children]. PMID- 6924373 TI - [Theoretical bases of the nursing process]. PMID- 6924374 TI - [For the health of others]. PMID- 6924375 TI - [Guests from Finland]. PMID- 6924376 TI - [Notes on education]. PMID- 6924378 TI - [Prevention of the loss of nutrients]. PMID- 6924377 TI - [Corticosteroid treatment]. PMID- 6924380 TI - [Infants and groups at risk]. PMID- 6924379 TI - [Efficacy of the Billings' method]. PMID- 6924381 TI - [Nursing at the age of development]. PMID- 6924382 TI - Nutrition in primary care. PMID- 6924383 TI - What is a healthful diet? PMID- 6924385 TI - Nutritional conditioning and athletic performance. PMID- 6924384 TI - Nutritional support during pregnancy and lactation. AB - Needs for virtually all nutrients increase during pregnancy and lactation but those for iron are the most difficult to meet from a normal diet. During pregnancy, nutritional objectives include helping the woman to increase the quality of her diet in protective nutrients as well as energy to meet the elevated needs of gestation, ensuring satisfactory weight gain patterns, prescribing iron and possible folic acid supplements, ensuring that intakes of alcohol, drugs, and other potentially harmful substances are moderate, preparing her for feeding the infant, and coping with any special diet-related problems that may arise. These issues and the management of edema, high blood pressure, and diabetes mellitus are discussed. Prenatal preparations for lactation and diet during lactation are also discussed. Specific objectives of nutritional education on lactation include helping the mother to make the decision to breast or bottle feed, taking steps to prepare her nipples if this is necessary and planning her diet. Dietary adjustments are discussed and a food guide presented. Iron supplements for ther lactating mother and iron, vitamin D, and fluoride supplements for the infant are recommended. PMID- 6924386 TI - The medical syndrome of obesity. AB - Obesity is one of the most common medical disorders and perhaps the least responsive to usual medical therapeutic approaches. The syndrome is often defined as greater than 20 per cent above ideal body weight for height; however, vagaries in establishing this relationship result in significant differences in estimates of its incidence. The effects of obesity on health are broad indeed and include many disorders, hypertension being the most consistently associated and potentially most lethal. Despite this significance, the medical practitioner's ability to treat obesity is severely restricted by inadequate training in nutrition, the nearly complete failure of the usually prescribed caloric restricted diet, and most importantly, the inappropriateness of the mode generally used in medical practice to address the complex interactions between diet, exercise, and behavior that are manifest in obesity. Failure on behalf of the medical community to address the problem has resulted in a commercial industry that consumes billions of dollars annually. Highly ethical, medically based alternatives to these commercial interests do not exist. Perhaps what is needed is the establishment of medical facilities that will provide practicing physicians, dietitians, nurses, and other health professionals with the capacity to bring to bear optimal dietetic intervention, exercise conditioning, and modifications of eating and exercise behavior as therapy for this complex medical disorder. PMID- 6924387 TI - Megavitamin therapy. PMID- 6924388 TI - Morphine analgesia--why does it vary from patient to patient? PMID- 6924389 TI - Pain and its severity in cancer patients. PMID- 6924390 TI - Improving pain management through staff education. PMID- 6924391 TI - Follow-up care evaluation: patient perspective. PMID- 6924392 TI - Using a level of function scale (LORS-II) to evaluate the success of inpatient rehabilitation programs. PMID- 6924393 TI - Nursing students' inpatient groups. PMID- 6924394 TI - Lend 'n ear: a therapeutic tool for speech rehabilitation. PMID- 6924395 TI - [Genetic factors Bf and glyoxalase in Basedow's disease]. PMID- 6924396 TI - [With lost body]. PMID- 6924397 TI - [A hospital unit has to be either open or closed]. PMID- 6924398 TI - [Memory in severe skull injuries]. PMID- 6924400 TI - [Echography of the biliary tract and of the gallbladder]. PMID- 6924399 TI - [Introduction to immunology. 2. Immuno-pathology]. PMID- 6924401 TI - [A nursing school in Great Britain]. PMID- 6924402 TI - [Silicosis]. PMID- 6924403 TI - [Non-tumoral hydrocephalus: diagnosis and treatment]. PMID- 6924405 TI - Rape crisis service open to all women. PMID- 6924404 TI - [Therapeutics: antiemetics]. PMID- 6924406 TI - Finding ideas for nursing our elders. PMID- 6924407 TI - Our attitudes toward cancer. PMID- 6924408 TI - Death with dignity: a dilemma for health care workers. PMID- 6924409 TI - Loculated pleural empyema: identification of complement breakdown products in contiguous sterile pleural fluid. AB - In view of the recent demonstration of complement consumption in human empyema, we searched for evidence of complement activation in 4 patients presenting initially with sterile postpneumonic effusions, but who were later shown to have contiguous loculated pleural empyemas. These results were compared with those obtained on 13 patients with postpneumonic uncomplicated effusions, and on 13 patients with primary empyema. C3d and Ba, respectively, breakdown products of complement components C3 and Factor B were both significantly elevated in the postpneumonic effusions of the 4 patients with loculated empyemas, when compared with those obtained in postpneumonic uncomplicated effusions (p less than 0.005). Total hemolytic complement activity (CH50) was similar in these 2 groups of pleural effusions. Plasma levels of C3d and Ba were undetectable, and CH50 values were within the same range in all groups of patients. These results suggest that the low molecular weight breakdown products of C3 and Factor B had diffused from the adjacent empyema, where active complement breakdown was occurring, into the sterile postpneumonic effusion. This study provides information about complement catabolism in extravascular sites during infection. The potential usefulness of this approach for the detection of loculated purulent collections is discussed. PMID- 6924411 TI - [Different aspects of health activities in a vocational education school]. PMID- 6924410 TI - [Cortancyl]. PMID- 6924412 TI - [Being a nurse in a vocational education high school]. PMID- 6924413 TI - [A nurse in a university milieu]. PMID- 6924414 TI - [School nursing: a little known specialty]. PMID- 6924415 TI - [Being a nurse in a special education section]. PMID- 6924416 TI - [A week in the life of a nurse at a national improvement school in Paris]. PMID- 6924417 TI - [School nursing today]. PMID- 6924418 TI - [From handicap to autonomy]. PMID- 6924419 TI - [Animation of the clinic of the technological and vocational Edouard Branly High School at Dreux]. PMID- 6924420 TI - [Being a nurse in a Paris suburb high school]. PMID- 6924421 TI - [Educating student nurses to be autonomous]. PMID- 6924422 TI - [A nurse in a Parisian high school]. PMID- 6924423 TI - [Urinary complications]. PMID- 6924424 TI - [Respiratory complications of bed rest]. PMID- 6924425 TI - [Bed rest: an avoidable pathology]. PMID- 6924426 TI - [Bronchial hygiene for bedridden patients]. PMID- 6924427 TI - [Cardiovascular complications of bed rest]. PMID- 6924428 TI - [Pathology of bed rest: prefatory]. PMID- 6924430 TI - [Pathology of bed rest: reflections expressed as a conclusion]. PMID- 6924429 TI - [Osseous, articular and muscular complications of bed rest and immobilization]. PMID- 6924431 TI - [Paraffin oil and its derivatives]. PMID- 6924433 TI - [Introduction to the pathology of bed rest]. PMID- 6924432 TI - [Training in handling patients. Economizing the personnel, not "of" personnel]. PMID- 6924434 TI - [Decubitus ulcers]. PMID- 6924436 TI - [Pseudodepression]. PMID- 6924435 TI - [Depression in the aged]. PMID- 6924437 TI - [Treatment of depression]. PMID- 6924438 TI - [Depression. A polymorph disorder in need of study]. PMID- 6924439 TI - [Role of the nursing staff facing the depressed patient]. PMID- 6924440 TI - [Obsessional neurosis]. PMID- 6924443 TI - [Experiment with a new health care structure in the framework of psychiatric department policy: "The Club"]. PMID- 6924441 TI - [Depression. Attempt to define it]. PMID- 6924442 TI - [An ulcer patient emigrates to the ... psychiatric department]. PMID- 6924445 TI - [Classical clinical aspects of depression--masked depression]. PMID- 6924446 TI - [Depression in childhood]. PMID- 6924444 TI - [Relationship with patients in psychiatric hospitals]. PMID- 6924447 TI - [Blood kallikrein-kinin system in the severe form of acute viral hepatitis]. PMID- 6924448 TI - The new tax changes. Part II. Educational costs and federal taxation. PMID- 6924450 TI - [Integrated approach: patients with multiple sclerosis]. PMID- 6924449 TI - Master's nursing education: preparing for leadership. PMID- 6924451 TI - [District nursing assistance to M.S. patients at home]. PMID- 6924452 TI - [Anneke: an M.S. patient]. PMID- 6924454 TI - [Social work and multiple sclerosis]. PMID- 6924453 TI - [Multiple sclerosis as disease]. PMID- 6924455 TI - [M.S. and rehabilitation]. PMID- 6924456 TI - [Multiple sclerosis: a physiotherapeutic stumbling-block?]. PMID- 6924457 TI - [Nursing aspects in the care of residents with multiple sclerosis]. PMID- 6924458 TI - Inhibitory effect of pancreatic elastase on thickening of the renal glomerular basement membrane in the spontaneously diabetic rat. AB - Effect of pork pancreatic elastase on thickening of the renal glomerular basement membrane was studied in three litter mates of the spontaneously diabetic rats by electron microscopic morphometry. Intramuscular injection of physiologic saline solution or elastase solution (5 mg/kg body weight/day) was repeated daily for 30 days. Renal cortex specimens were obtained before and after the injection in two litter mates. Renal glomerular basement membrane thickness (RGBMT) of the rats injected with saline increased markedly, whereas RGBMT of the rats treated with elastase remained close to the initial value. In each of the three litter mates, RGBMT after the treatment was significantly thinner in the elastase injected rats than in the saline injected rats. PMID- 6924459 TI - Legal ledger: informed consent. PMID- 6924461 TI - Interview: Mary Schwind-Richeal. PMID- 6924460 TI - Mechanical ventilation: the patient's viewpoint. PMID- 6924462 TI - Once a vibrant eucalyptus. PMID- 6924463 TI - Cesarean childbirth: current perspectives. PMID- 6924465 TI - The role of anesthesia in outpatient surgery. PMID- 6924464 TI - Pre and postoperative fluids and electrolytes: nursing assessment and intervention. PMID- 6924466 TI - Interview: Beverly March. PMID- 6924467 TI - How to run an OR open house: one hospital's story. PMID- 6924468 TI - Malpractice insurance. PMID- 6924469 TI - The truth about nurses: as kids tell it. PMID- 6924470 TI - Diabetic student: the rest of the story. PMID- 6924472 TI - The OR over the years. PMID- 6924471 TI - Paternalism versus humanism: a continuum for patient education. PMID- 6924473 TI - How to improve morale and increase productivity. PMID- 6924478 TI - Coping with stress following natural disasters: individual, health care provider, and community responses. PMID- 6924474 TI - Communicating nursing research. Volume 15. Nursing science in perspective. PMID- 6924476 TI - Theoretical model testing: full data utilization. PMID- 6924479 TI - Methodological problems and selected strategies. PMID- 6924475 TI - Keynote address: the research cycle: nursing, the profession, the discipline. PMID- 6924477 TI - Nursing administration research: head nurses and staff nurses. PMID- 6924480 TI - Psychological preparation and supportive care for mastectomy patients. PMID- 6924481 TI - Cancer patient responses to psychosocial variables. PMID- 6924484 TI - Sudden cardiac death. PMID- 6924482 TI - Current menstrual cycle research. PMID- 6924483 TI - Sparsely populated areas: toward nursing theory. PMID- 6924485 TI - Family as context and focus: a new research frontier. PMID- 6924487 TI - Publishing in non-refereed journals is not only O.K.--it's necessary. PMID- 6924486 TI - Is there a difference in gender stress response? PMID- 6924488 TI - Psychosocial aspects of coronary heart disease: implications for nursing research. PMID- 6924491 TI - Ethical issues in nursing research. PMID- 6924490 TI - Loneliness: its relationship to the educational experience of international nursing students in the United States. PMID- 6924489 TI - Ethnicity: the development of an empirical construct for cross-cultural health research. PMID- 6924492 TI - Problems in doing nursing research: maximizing the group research process. PMID- 6924493 TI - Strategies for teaching nursing research: using secondary data in needs assessment approach to nursing assessment. PMID- 6924494 TI - Researchmanship: removing obstacles to research in the clinical setting. PMID- 6924495 TI - [Swedish Nurses' Association's representative meeting: increased central administration - 2 new membership meetings]. PMID- 6924496 TI - [Silver nitrate methods does more harm than good. Interview by Jan Thomassen]. PMID- 6924497 TI - [Following the TCO equality course: entirely too ticklish for a course. Interview by Inger Lernevall]. PMID- 6924498 TI - [Following the TCO equality course: now we understand each other better. Interview by Inger Lernevall]. PMID- 6924499 TI - [TCO stresses peace questions]. PMID- 6924500 TI - [We must blow life in professions' ideology]. PMID- 6924501 TI - [Anna on scholarship in the USA writes a letter home to Sweden: "work assignments just as changeable as salaries"]. PMID- 6924503 TI - [A new idea tested: counseling on your economy]. PMID- 6924502 TI - [New method of testing vision in infants]. PMID- 6924505 TI - [Proposal for wage policy program: work assignment should determine your wages]. PMID- 6924504 TI - [Eritrean Liberation Front's hospital in Sudan: goal is basic health care for all]. PMID- 6924506 TI - [Rounds should be a reciprocal interchange between patients and personnel]. PMID- 6924507 TI - [SHSTF and MAF lend an ear to their roentgen needs: entirely new organization within primary health care]. PMID- 6924510 TI - [Research in Lund: here clinical instructors are no casual visitors]. PMID- 6924509 TI - [Cytostatic agents can cause severe damage if one does not protect oneself in the right way]. PMID- 6924508 TI - [Now principles have hit hard again but women may strike for equality]. PMID- 6924512 TI - [Personnel should be educated in care of dying patients]. PMID- 6924511 TI - [Anne, following SHSTF's mass media course in Kalix: "enlightening, I have learned a lot". Interview by Kjell Vagnhammer]. PMID- 6924514 TI - [Final report on health care: Utopia or necessity?]. PMID- 6924513 TI - [SHSTF management on the State Bacteriologie Laboratory: we struggle against division of the SBL]. PMID- 6924516 TI - [The Army reorganizes: now company nurses are inducted]. PMID- 6924515 TI - [Work Tribunal decides in the Fall: right to roentgen holidays as well as professional priority?]. PMID- 6924517 TI - [She was reluctant to become a Ph.D., now she is left without a job. Interview by Viveka Holmertz]. PMID- 6924518 TI - [SSEF (Student Nurses' Society) discusses own certification. Interview by Inger Lernevall]. PMID- 6924519 TI - [Patients can be cared for in the home as long as possible]. PMID- 6924520 TI - [340 participants in the international conference in Uppsala: interest increased for health care research]. PMID- 6924521 TI - [Child welfare schools change employers: conditions for employees clarified]. PMID- 6924522 TI - [Wanted: nurses. Reward offered]. PMID- 6924523 TI - [In Angelholm it's enough to be only a nurse. Assistant stopped - cannot become a hospital administrator]. PMID- 6924524 TI - [Unemployment, education, limit-setting questions: Student Nurses' Society meets with SHSTF and Municipal Government for a discussion]. PMID- 6924525 TI - [Labor market situation overall turbulent. Gavle Hospital employs nurses in relief work]. PMID- 6924527 TI - [Signe visited Hiroshima and Nagasaki after the atom bomb: "What I saw and heard then was the biggest shock". Interview by Jan Thomasson]. PMID- 6924528 TI - [Like a Galahad in search of the Grail. Interview by Susanna Stubbendorff]. PMID- 6924526 TI - [Eva, Kristina and Lisbeth will start a peace society for SHSTF members: "Our job will be to save life". Interview by Jan Thomasson]. PMID- 6924530 TI - [Criticism of new Swedish code for marketing of infant food]. PMID- 6924529 TI - [We should place our expert knowledge at the disposition of the politicians. Interview by Susanna Stubbendorff]. PMID- 6924531 TI - [Action programs for working with ionizing radiation clarified: an aid in setting requirements for a safer work environment]. PMID- 6924533 TI - [Long lines, overoccupancy, poor working conditions: closed-down hospital occupied in protest]. PMID- 6924532 TI - [Margaretha was not satisfied with traditional role; "I want to work more practically with the patient". Interview by Jan Thomasson]. PMID- 6924534 TI - [Kirsten Stallknecht, president of the Danish Nursing Council: it would be better for oppositions to work within the organization. Interview by Jan Sjunnesson]. PMID- 6924535 TI - [Angry students demand an answer: we want to know for what we were educated]. PMID- 6924536 TI - [Midwife returns home to Berit - what service!. Interview by Viveka Holmertz]. PMID- 6924537 TI - [Activation of the alternative complement pathway in pleural fluid of patients with pneumonia]. AB - It has been reported that the opsonic activity of pleural fluid is decreased in patients with pneumonia complicated by infected effusions (empyema) compared to those with sterile (metapneumonic) effusions. In this paper some parameters of complement activity in 12 patients with empyema and in 13 patients with metapneumonic effusions were compared. The hemolytic activity of the alternative pathway and of Factor B in empyemas (15 +/- 10% and 25+15%, respectively) was less than that measured in metapneumonic effusions (55 +/- 38% and 71 +/- 21%; p less than 0.01). Both parameters showed a significant correlation (r=0.76; p less than 0.01). The Ba fragment, a catabolic product of Factor B, was increased in empyema (125 +/- 59%) compared to that in metapneumonic effusions (49 +/- 24%; p less than 0.01). The levels of C3, protein of both, alternative and classical pathways, were decreased in empyema (17 +/- 29%) when compared with the levels in metapneumonic pleural effusion (42 +/- 20%; p less than 0.01). The levels of this protein were correlated with the activity of alternative complement pathway (r=0.68; p less than 0.01), as well as with those of Factor B (r=0.75; p less than 0.01). Finally, the hemolytic activity of C4, as a representative element of the classical pathway, has also shown to be decreased in empyema (6 +/- 6%) compared to metapneumonic fluids (27 +/- 28%; p less than 0.01). Significant correlations between the hemolytic activity of C4 and levels of C3 (r=0.75; p less than 0.01), the hemolytic activity of the alternative pathway (r=0.63; p less than 0.01) and the levels of Factor B (r=0.73; p less than 0.01) were demonstrated. This last suggest a simultaneous activation of both, classical and alternative pathways of complement. The complement decrease and particularly, the activation of the alternative pathway in patients with empyema could be a determinant factor of the deficient bacterial opsonization. This can explain the survival of bacteria in an empyema despite the large number of neutrophils present. PMID- 6924538 TI - Single-dose amoxicillin therapy with follow-up urine culture. Effective initial management for acute uncomplicated urinary tract infections. AB - To learn whether a single dose of amoxicillin is safe, effective therapy for acute uncomplicated urinary tract infections, 388 symptomatic nonpregnant women were randomly grouped to receive oral amoxicillin, either as a single 3 g dose of 250 mg three times a day for two weeks. Patients had quantitative as well as dip slide cultures of urine and tests for antibody-coated bacteria in urine. Follow up urine cultures were obtained one week after completion of treatment. Results of antimicrobial susceptibility and antibody-coated bacterial tests did not alter the randomized therapy. Among 162 patients with bacteriologically confirmed infections, cure rates were 60.6 percent (43 of 71) for single-dose versus 73.6 percent (67 of 91) for two-week treatment (p = 0.07). Although more antibody coated bacteria-negative patients (89.6 percent; 26 of 29) were cured overall, a substantial proportion of antibody-coated bacteria-positive patients were also cured by both single-dose (59.3 percent; 32 of 54) and 14-day therapy (64.6 percent; 42 of 65). There were fewer adverse effects in the single-dose treatment group. We conclude that a single 3 g dose of amoxicillin, with follow-up urine culture, provides safe and effective management for acute uncomplicated urinary tract infections in nonpregnant women. PMID- 6924541 TI - An influenza outbreak in a hospital. PMID- 6924539 TI - Helping the patient in pain. PMID- 6924542 TI - Psychological aftereffects of halo traction. PMID- 6924540 TI - Foster grandmothers in the premature nursery. PMID- 6924544 TI - What every nurse should know about vaginitis. PMID- 6924543 TI - The economic value of nursing research. PMID- 6924545 TI - Non-nursing functions: our readers respond. PMID- 6924546 TI - The hospitalized alcoholic. PMID- 6924547 TI - The hidden diagnosis. PMID- 6924548 TI - Avoiding a crisis: the assessment. PMID- 6924550 TI - An alcohol treatment team. PMID- 6924549 TI - The hospitalized alcoholic. Hospital dialogues. PMID- 6924551 TI - The legal side: gaps in documentation. PMID- 6924554 TI - Understanding aspects of staff development aids its effective use. PMID- 6924552 TI - Effects of oral and injectable tetracyclines on bacterial drug resistance in feedlot cattle. AB - Enteric bacteria isolated from feedlot heifers treated with tetracyclines (TET) were examined for resistance to TET and ampicillin. The effects of feeding (45 days) therapeutic and subtherapeutic quantities of chlortetracycline (CTC) and the injection of therapeutic doses of oxytetracycline (3 daily doses) were compared. Performance data from the 45-day trial did not identify an antibiotic effect on average daily gain, although cattle fed subtherapeutic quantities of CTC showed improved feed efficiency. Bacterial resistance to TET was increased in the heifers given the therapeutic and subtherapeutic quantities of CTC in the ration. However, an increase in resistance to ampicillin did not occur. Oxytetracycline injections had a short-term effect, increasing the number of resistant organisms only during the week of drug administration. PMID- 6924553 TI - Differing susceptibility of young and adult hamster lungs to injury with pancreatic elastase. AB - A study was undertaken to determine whether there are differences in the initial response of the lungs of young (28 days) and adult (105 days) hamsters to pancreatic elastase treatment. The elastase was given intratracheally (0.1 mg/100 g body weight), and the animals were studied 24 h later. The mean linear intercept of the lungs of young animals increased less than that of adult animals (p less than 0.05). Adult body weights decreased significantly with elastase treatment, whereas those of young elastase-treated animals did not. The lungs of young animals gained proportionately less weight than those of adult animals, suggesting they experienced less hemorrhage and edema. When the volumes, at given transpulmonary pressures, of fluid-filled lungs were expressed as percent predicted, the values for young animals were significantly less than those for adult animals. The most pronounced differences were at low transpulmonary pressures (1 to 3 cm H2O). Volume-pressure hysteresis was not altered by elastase treatment in either the young or adult animals. We conclude that the lungs of adult hamsters are more susceptible to elastase injury than the lungs of young hamsters. PMID- 6924555 TI - When your patient is also pregnant. PMID- 6924556 TI - Caring for emotional needs of orthopedic trauma patients. PMID- 6924557 TI - Total knee replacement. PMID- 6924558 TI - Arthroscopic surgery of the knee joint. PMID- 6924560 TI - Identifying learning needs: a teaching for emergency procedures. PMID- 6924559 TI - RN says clinic design needs input from nurses. PMID- 6924561 TI - Hypothermia in the postanesthetic patient. PMID- 6924562 TI - Staff nurses can inspire OR changes. PMID- 6924566 TI - Ileal loop and body image. PMID- 6924563 TI - Coagulum pyelolithotomy to remove multiple stones. PMID- 6924564 TI - A new look at old problems. PMID- 6924565 TI - Vascular assess procedures for hemodialysis. PMID- 6924569 TI - The nurse and the law: pregnancy and birth. PMID- 6924567 TI - Changes in pH sensitivity of adenylate cyclase specifically induced by fluoride and vanadate. PMID- 6924570 TI - The food factor and the scientific nurse: dietary management of diabetes mellitus. PMID- 6924571 TI - Non-steroidal anti-inflammatory drugs. PMID- 6924568 TI - The effect of chelating agents on vanadium distribution in the rat body and on uptake by human erythrocytes. AB - Pentavalent vanadium (V5) as Na48VO3 was given i.p. to male Wistar rats at a dose of 5 mumol/kg in order to study its organ distribution pattern. Two days after injection, kidneys reached a V level of about 28 nmol/g wet weight, followed in decreasing order by spleen, liver, bone, blood plasma, testis, lung, erythrocytes and brain in control rats. A similar distribution pattern was seen after injection of tetravalent vanadium (V4) given as 48VOSO4. Two chelators, desferrioxamine B (Desferal) or Ca-Na3-diethylene triamine pentaacetic acid (DTPA), were given i.p. 24 h after the vanadium injections to different groups of rats at two dosage levels, 30 and 100 mumol/kg. Desferal (30 mumol/kg) reduced the vanadium content of the kidney by 17%, of the liver by 0%, and of the lung by 7%. The corresponding figures for the effect of DTPA (30 mumol/kg) were 7%, plus 15%, and 0%, respectively. At 100 mumol/kg, Desferal reduced the same organ levels by 20%, 26%, and 25%, respectively, and DTPA by 9%, 18%, and 25%, respectively. Both chelators raised faecal excretion at the low level, and both urinary and faecal excretion at the high level. Spleen and bone seemed to bind vanadium to a higher degree than the other organs under examination. Human erythrocytes, when incubated with 48VOSO4 (V4) or Na48VO3 (V5), were found to accumulate nearly the double amount of V5 as compared to V4. Glutathione (GSH) which is the main reducing substance within the erythrocytes, reduced the uptake of V5 to the V4 level when incubated together with GSH before addition to the cell suspension. Pretreating the erythrocytes with diethyl-maleate (DEM) which blocks the reducing SH groups of intracellular GSH, also reduced the uptake of V5. This may indicate a GSH dependent reduction of V5 to V4 within the erythrocytes. Four chelators, among them Desferal and DTPA, were found to reduce the cellbound amount of vanadium, either by extracting vanadium as V4, or by inhibiting uptake by the red blood cells. PMID- 6924572 TI - Tetanus examined. PMID- 6924575 TI - The role of the infection control sister. PMID- 6924573 TI - Choosing criteria for choosing nurses. PMID- 6924574 TI - 'Interpreting' the needs of migrants. PMID- 6924576 TI - Some aspects of nursing from a community basis in W.A. PMID- 6924577 TI - Solving problems means asking questions. PMID- 6924578 TI - Principles to be considered in fertility control. PMID- 6924580 TI - The sudden infant death syndrome--it does not have to exist. PMID- 6924579 TI - Ethical validity of life support treatments. PMID- 6924581 TI - Christian principles in the care of the dying. PMID- 6924582 TI - Homebirth news. PMID- 6924584 TI - Developmental maturity of adolescent and young adult patients on chronic hemodialysis: a comparative study. PMID- 6924583 TI - Studies on the temperature-dependent autoinhibition of human plasma kallikrein I. AB - At 37 degrees C, human plasma kallikrein I follows Michaelis-Menten behaviour and exhibits a normal linear relationship between the initial velocity of hydrolysis of Ac-Pro-Phe-Arg-OMe,HCl and enzyme concentration in the range 0--150 pM. At temperatures of 30 degrees C and below substantial deviations from linearity are observed over the same enzyme concentration range. The temperature-dependent autoinhibition of kallikrein I activity is reversible and is not due to low molecular-weight endogenous inhibitors or cofactors. The kinetic effect is apparently due to aggregation and can be abolished by the addition of sodium deoxycholate. PMID- 6924585 TI - Evaluation of an experimental education program for new dialysis patients. PMID- 6924587 TI - The National Federation for Specialty Nursing Organizations: a perspective. PMID- 6924586 TI - Illness behavior of dialysis patients, staff response, and coping measures. PMID- 6924588 TI - A new model for organized nursing. PMID- 6924589 TI - Credentialing for nephrology nurses and technicians. PMID- 6924590 TI - Mechanisms of stimulation of protein synthesis in regenerating liver. PMID- 6924592 TI - An improved method of isolation of rat pancreatic prokallikrein. Characterization of the zymogen and of the kallikrein produced by trypsin activation. AB - A prokallikrein was purified 1600-fold from rat pancreatic tissue in an overall yield of 40% by a simple four-stage procedure. The final and crucial step was immunoaffinity chromatography utilizing antibody raised to a very small amount of prokallikrein. Both the pure zymogen and the active kallikrein generated from it by trypsin activation are single chain species with Mr values of 38400 +/- 300 and 35500 +/- 400, respectively. Valine is the N-terminal amino acid residue of prokallikrein. The zymogen was comparatively stable both to autoactivation and denaturation with respect to temperature and pH. The kallikrein produced by trypsin activation of the zymogen was similar in some of its catalytic properties to the kallikrein purified from autolyzed rat pancreas but the two species differed in their susceptibility to substrate activation. PMID- 6924591 TI - Binding of spermidine to transfer ribonucleic acid. AB - The binding of spermidine to yeast tRNAPhe and Escherichia coli tRNAGlu2 at low and high ionic strength was studied by equilibrium dialysis. Once corrected for the expected Donnan effect, the binding at low ionic strength obeys the simple relationship of equivalent binding sites, and cooperative binding of spermidine to tRNA could not be detected. At low ionic strength (0.013 M Na+ ion), tRNAPhe (yeast) has 13.9 +/- 2.3 strong spermidine binding sites per molecule with Kd = 1.39 X 10(-6) M and a few weak spermidine binding sites which were inaccessible to experimentation; tRNAGlu2 (E. coli) has 14.8 +/- 1.6 strong spermidine binding sites and 4.0 +/- 0.1 weak spermidine binding sites with Kd = 1.4 X 10(-6) M and Kd = 1.23 X 10(-4) M, respectively. At high ionic strength (0.12 M monovalent cation) and 0.01 M Mg2+, tRNAPhe (yeast) has approximately 13 strong spermidine binding sites with an apparent Kd = 3.4 X 10(-3) M while the dimeric complex tRNAPhe X tRNAGlu2 has 10.4 +/- 1.2 strong spermidine binding sites per monomer with an apparent Kd = 2.0 X 10(-3) M. In the presence of increasing Na+ ion or K+ ion concentration, spermidine binding data do not fit a model for competitive binding to tRNA by monovalent cations. Rather, analysis of binding data by the Debye-Huckel approximation results in a good fit of experimental data, indicating that monovalent cations form a counterion atmosphere about tRNA, thus decreasing electrostatic interactions. On the basis of equilibrium binding analyses, it is proposed that the binding of spermidine to tRNA occurs predominantly by electrostatic forces. PMID- 6924593 TI - A rationale for identification of cases of drug abuse. AB - To overcome the blanket of secrecy developed by many drug-abusing populations, special strategies have been used to generate more reliable and valid data on the extent and nature of the problem. The epidemiological rationale for eight strategies to identify cases of drug abuse are reviewed along with their limitations and examples of their application. The choice of strategies in any given setting will depend upon the drug-use patterns and legal framework of the particular society, the form of social organization developed by drug abusers and the types of contact they have with formal institutions such as law enforcement and treatment agencies. PMID- 6924594 TI - Epidemiologic field units on narcotic-related problems. AB - Much more understanding is needed of the epidemiology of narcotic-related problems. This paper describes a research strategy which is responsive to the heterogeneous nature of such problems. It is suggested that it is feasible and useful to establish, for defined geographic areas, epidemiologic field units which would have continuity, be comprehensive and develop programmatically relevant information on a timely basis. The possible areas of inquiry and the components of such a unit are discussed. PMID- 6924596 TI - Constituents of Cannabis sativa L. XXII: isolation of spiro-indan and dihydrostilbene compounds from a Panamanian variant grown in Mississippi, United States of America. AB - Three spiro-compounds, namely cannabispiran, dehydrocannabispiran and beta cannabispiranol, and 2 dihydrostilbenes [3-(2-(3-hydroxy-4-methoxyphenyl)ethyl)-5 methoxyphenol and canniprene] were isolated from a polar fraction of a Panamanian variant of Cannabis sativa L. grown in Mississippi, United States of America. The plant material was extracted with 95% ethanol and the dried ethanol extract was then partitioned between chloroform and water. The chloroform fraction was fractionated between hexane and 3N sodium hydroxide solution. Acidification of the basic fraction followed by extraction with ether afforded a polar acidic fraction from which the above-mentioned compounds were isolated through repeated chromatography. The structures of the above compounds were determined by spectral means as well as by comparison with reference samples. The isolation of two dihydrostilbenes and three spiro-indan compounds from a single variant provides good support that the dihydrostilbenes are the natural precursors to the spiro indan compounds. PMID- 6924595 TI - Research on drug dependence in India. AB - The persistent problem of drug dependence has been studied in India from several disciplinary angles. The present exercise attempts to answer the question of whether these efforts have been able to build up a dependable and comprehensive body of literature. While available studies show the magnitude of the problem in different population groups, there are obvious information gaps which discourage attempts to evolve countrywide estimates. This is also the case with such aspects as personal attributes of drug users, socio-cultural background and psychological characteristics. Such data gaps show up further when processes of experimentation or abstinence, as well as psychosocial implications, are examined. These considerations call for the intensification of research activities, development of a co-ordinated research programme and the investigation of the problem from different disciplinary perspectives. PMID- 6924597 TI - The role of the oncology clinical nurse specialist: three personal views. PMID- 6924598 TI - Helping parents of children with cancer during the midstage of illness. PMID- 6924600 TI - A chance to be normal again. PMID- 6924599 TI - Assessing patient self-care for side effects of cancer chemotherapy--part I. PMID- 6924601 TI - Amphotericin B: effective management of adverse reactions. PMID- 6924602 TI - Acute periodontal infection in myelosuppressed oncology patients: evaluation and nursing care. PMID- 6924603 TI - Nurses' knowledge of breast reconstruction: a catalyst for earlier treatment of breast cancer? PMID- 6924604 TI - Clinical versus statistical significance. PMID- 6924605 TI - Data management and the cancer treatment protocol. PMID- 6924606 TI - [Affinity chromatography of serum kallikreins with the electrophoretic mobility of immunoglobulins]. PMID- 6924607 TI - A comparative study on the measurement of urinary kallikrein in the rat. PMID- 6924608 TI - Porcine pancreatic prokallikrein. II. Purification and some properties of prokallikrein A. PMID- 6924610 TI - Skin burns due to wet cement. PMID- 6924609 TI - Circulating immune complexes in Indian childhood cirrhosis. AB - Considerable immunological dysfunction has been reported in Indian childhood cirrhosis (Chandra, 1970; Chawla et al., 1973). These observations suggest that the progressive tissue damage observed in this disease may have an immunological basis. To further test this hypothesis, sera from 18 patients with Indian childhood cirrhosis (ICC) and nine age-matched siblings were examined for the presence of soluble immune complexes and activation of complement. The presence of circulating immune complexes (CIC) in ICC is reported for the first time. Immune complexes were measured by the liquid phase 125I-Clq binding (Clq BA) and 125I-conglutinin binding (KBA) assays, and observed in 13/18 (72%) and 10/18 (56%) patients respectively. A significant correlation was found between the two tests. In contrast, only two out of nine siblings had elevated levels of immune complexes, and these were positive in both tests. Evidence was also obtained for in vivo activation of complement via the classical pathway. Total haemolytic complement (CH50) values were depressed in 13/18 (72%) patients, while C4 and C3 values were low in 5/16 (31%) and 4/18 (22%) patients respectively. C3 degradation products were found in substantial amounts in six patients. Complement levels in siblings were uniformly normal. These observations suggest that the immune complexes demonstrated may be of phlogistic significance and merit further characterization. PMID- 6924611 TI - Respiratory care update! Sputum and the "toilet". PMID- 6924612 TI - Management of the patient with chest trauma (CEU home study). PMID- 6924613 TI - Avoiding professional malpractice. PMID- 6924614 TI - Infection control update! Rubella (German measles or 3-day measles). PMID- 6924615 TI - Spiritual care... planting seeds of hope. (CEU home study). PMID- 6924617 TI - Assessing activity tolerance in critical care settings. PMID- 6924618 TI - CPR marathon '82. PMID- 6924619 TI - Electrical safety: the electrically sensitive ICU patient. PMID- 6924616 TI - The mode of action of the antitumor drug bouvardin, an inhibitor of protein synthesis in eukaryotic cells. AB - Bouvardin is an antitumor drug that inhibits protein synthesis in intact eukaryotic cells and cell-free systems. Our present studies have shown that bouvardin acts at the level of the 80 S ribosome in a site somehow involved with the interaction of EF1 and EF2. Indeed bouvardin inhibits EF1-dependent binding of aminoacyl-tRNA and EF2-dependent translocation of peptidyl-tRNA but does not affect the nonenzymic translocation since this reaction does not require EF2. The site of the 80 S ribosome involved in the interaction with bouvardin appears to be independent from the cycloheximide and the cryptopleurine binding sites since yeast mutants resistant to cycloheximide or cryptopleurine are sensitive to bouvardin. PMID- 6924620 TI - The future of critical care nursing. PMID- 6924622 TI - Legal issues in nursing. PMID- 6924623 TI - Utilization of computers in the management of critically ill patients. PMID- 6924625 TI - [Diagnosis of intrauterine growth retardation--comparison of clinical findings, total oestrogen determination from 24-hour urine and ultrasound biometry (distance measurement, biparietal head diameter and thoraco-abdominal transverse diameter) considering the antepartal and subpartal CTG's]. AB - This article presents the results of clinical examination, total oestrogen determination from 24-h urine and ultrasound biometry -- measurement of the biparietal head diameter and the thoraco-abdominal transverse diameter (under routine conditions) -- for diagnosing intrauterine growth retardation (IUGR). In addition, the antepartal and subpartal CTG's are evaluated in cases of foetal retardation of growth "Single determinations" are confronted with so-called "serial examinations (= observation of the course)". Repeated clinical examinations and multiple determinations of the total oestrogen elimination with the 24-h urine did not result in any clear improvement of the detection rates of deficient development of the foetus (discovery rate with clinical examination = 54%, total oestrogen determination = 60%); there was, in fact, a relatively high rate of false-positive diagnosis (false-positive diagnoses on clinical examination = 31%). On the other hand, simple ultrasound biometry (distance measurements) led to the discovery of about 78% of all foetal growth retardations (perc. less than 10), the false-positive diagnoses rate being only 9%. Pathological antepartal CTG's (less than 8 points according to the Meyer-Menck score) were seen in about 27% of the cases with growth retardation -- with, however, an approximately equal rate of pathological CTG's in newborn of "normal weight". The discovery rate of deficient development of the foetus has been increased by combining ultrasound biometry with the total oestrogen determination from the 24-h urine, to 88% (perc. less than 10). The same applies to the combination of ultrasound biometry with the clinical examination (rate of detection: 87%). Up to 77% of all cases with IUGR have been discovered both by combining the clinical examination with the total oestrogen determination or antepartal CTG, as well as by combining total oestrogen determination with antepartal CTG. PMID- 6924627 TI - [On the incidence and mortality of carcinoma of ovary in the Federal Republic of Germany 1968-1979]. PMID- 6924626 TI - [Echographic investigation of the calyceal system in cases of pyelitis gravidarum]. AB - Dilatation of the upper urinary tract can be found even in pregnancies of healthy women. The frequency of dilatations in patients with pyelitis gravidarum is higher. Comparing the symptoms -- costovertebral tenderness and significant bacteriuria -- with the nephrosonograms it can be demonstrated that urinary tract infections incline to reoccur in patients with dilated upper urinary tract despite adequate antibiotic therapy. Echographic examination of the calyceal system during pregnancy might therefore be useful in detecting risk patients who have to undergo intense urologic surveillance. PMID- 6924624 TI - Two in one: steps to establishing a successful joint practice. PMID- 6924621 TI - A PhD--would I do it again? PMID- 6924629 TI - [Diffuse lymphangiomatosis of the breast in adults]. PMID- 6924628 TI - [Cytologic cancer prevention in the vulva. Morphologic study of an extensive case material]. AB - 464 patients, 286 healthy patients and 178 patients with lesions of the vulva had cytological and/or histologic examinations of the vulva. The normal vulva sheds in approximately 50% of the cases anucleate squames and in approximately 50% of the cases parakeratotic cells. In benign lesions of the vulva, in 1/3 of the cases each one finds either and anucleate squames, parakeratotic cells or mildly dyskariotic cells. In premalignant lesions 1/2 of the cases exfoliate mildly dyskariotic cells and the other 1/2 severely dyskariotic cells. In carcinoma of the vulva cytologic evidence of cancer is found in approximately 60% of the cases whereas 34% of the cases only show severely dyskariotic cells and 6% only mildly dyskariotic cells. Ulcers and defects do not increase the yield of exfoliated tumour cells. Exfoliative cytology of the vulva is considered to be an important part of the early diagnosis of cancer of the vulva. PMID- 6924630 TI - [The primary non-Hodgkin lymphoma of the mammary gland]. AB - Basing on an observation made by the authors, the article describes the diagnostic and therapeutic criteria in primary non-Hodgkin lymphoma of the mamma. Despite high malignancy, especially of the lymphoblastic-centroblastic lymphoma and of the immunoblastic lymphoma (Stein, 1974), permanent healing can be achieved via early surgical treatment and subsequent radiotherapy. In the case under discussion, the same tumour reappeared in the contralateral breast after an interval of five years. Since it was possible to exclude a generalisation, it must be assumed that the patient in question had a primary non-Hodgkin lymphoma of the immunoblastic type in both mammae after a period of five years. PMID- 6924632 TI - [Spontaneous rupture of the liver following caesarean section: a rare complication of an eclamptic liver]. PMID- 6924633 TI - Studies on the excretion of tissue kallikrein from blood into the urine. AB - Enzymatically active or diisopropyl fluorophosphate-inactivated pig pancreatic kallikrein were infused intravenously into dogs. Pig pancreatic kallikrein in plasma and urine was measured by a radioimmunoassay. The total excreted pig pancreatic kallikrein was 0.8-3.1% of the administered dose when active kallikrein was infused and 21.6% when inactive kallikrein was infused. The renal clearance of the administered kallikrein was found to be between 0.9 and 4.1 ml/min, which corresponds to 2.4-6.4% of the inulin or creatinine clearance. These results indicate that renal synthesis of tissue kallikrein and its direct secretion into the urine is not the exclusive mechanism of the excretion of tissue kallikrein into the urine. A second mechanism, the renal transfer of endogenous tissue kallikrein from the blood into the urine, can also contribute to the total amount of excreted urinary kallikrein. PMID- 6924631 TI - [Pregnancy termination in convulsive eclampsia using a "prostaglandin-cap"]. AB - Five cases of eclampsia are reported where, since the cervix was immature, pregnancy was terminated with local application of prostaglandin E2 by means of a portio-adapter. Induction-delivery time was short in each instance; in only one patient mild side effects common to prostaglandins were observed. In all five patients operative delivery could be avoided. Shortly after expulsion of the fetus all patients were symptom-free, all post partum courses were uneventful. Three fetuses were already dead before induction of labour, the remaining two weighing 850 g and 1000 g died of respiratory distress syndrome on post partum day five and nine. Local application of PGE2 by means of a portio-adapter can be considered a serious improvement in the therapy of convulsive eclampsia. PMID- 6924634 TI - Kininogenase activity in rat uterus homogenates. AB - A synthetic peptide substrate for tissue kallikreins was hydrolysed by uterus homogenates. These also released kinins when incubated with dog kininogen. By using high pressure liquid chromatography in combination with a radioimmunoassay for kinins, the peptides released were identified as bradykinin and kallidin. Plasma kallikrein and trypsin released bradykinin from dog kininogen and hog pancreas kallikrein released kallidin from this substrate. This suggests that a tissue kallikrein and also a trypsin-like enzyme or perhaps plasma kallikrein are present in rat uterus. PMID- 6924635 TI - Methicillin resistant staphylococci. PMID- 6924637 TI - Factors influencing the quality of wards as learning environments for student nurses. PMID- 6924639 TI - Community psychiatric nursing services in Britain: the need for policy and planning. PMID- 6924638 TI - Early detection of cancer in the elderly: problems and solutions. PMID- 6924636 TI - Competency based learning: a literature review. PMID- 6924640 TI - Anxiety and depression in general and psychiatric nurses: a comparison. PMID- 6924641 TI - CDC guideline recommendation questioned. PMID- 6924642 TI - Australia develops new antibiotic test method. PMID- 6924643 TI - Hospital infection control--an international perspective. PMID- 6924645 TI - Q fever control measures: recommendations for research facilities using sheep. AB - Q fever (Query Fever) is a zoonosis caused by the rickettsia Coxiella burnetii. domestic ungulates such as sheep, cattle, and goats serve as the reservoir of infection for humans and shed the desiccation-resistant organism in urine, feces, milk, and especially in birth products. In humans the illness is generally mild; however, Q fever hepatitis is often seen and Q fever endocarditis is an uncommon, but frequently fatal complication. Q fever long has been recognized as an occupational hazard among persons working with animals or animal products, and in laboratories working with C. burnetii. Recently, Q fever outbreaks have occurred in medical research facilities using sheep as research animals. Recommendations are presented for reducing the risk of exposure to Q fever in persons not working with sheep in research facilities that use sheep. In addition, recommendations are presented for reducing the risk of infection in persons who work with sheep in research facilities. PMID- 6924646 TI - An evaluation of daily bacteriologic monitoring to identify preventable episodes of catheter-associated urinary tract infection. AB - We evaluated the efficacy of a daily bacteriologic monitoring program for preventing symptomatic urinary tract infections (UTI) in hospitalized patients with temporary indwelling urethral catheters. We identified 99 instances in which bacteriuria was present at the time of catheter insertion among 1,140 catheterizations. Of those, 62 patients were asymptomatic and 37 patients had fever or symptoms attributable to UTI. Of the 37 symptomatic episodes, only 14 developed symptoms 24 hours or more after the first culture and might be considered potentially preventable. We also identified 76 episodes of acquired bacteriuria among 608 catheterizations that were initially nonbacteriuric in which at least two cultures were available. Of these 76 patients, 51 (67%) remained asymptomatic throughout their period of hospitalization. Of the 25 patients who developed symptomatic infections, only ten were potentially preventable. In all, only 24 symptomatic episodes among 1,140 catheterizations (2%) occurred 24 hours or more after colonization was first detected and might be considered potentially preventable. Our data suggest that routine daily bacteriologic monitoring of urine from all catheterized patients is not an efficient way to decrease the incidence of symptomatic, catheter-associated UTI. PMID- 6924644 TI - Investigation of an epidemic of multi-drug resistant Pseudomonas aeruginosa. AB - Inter- and intrahospital epidemics of nosocomial infections due to gram-negative bacilli resistant to many antimicrobials have been well-documented. Prospective studies on the use of isolation along with epidemiologic analysis and appropriate environmental control have been lacking. In the six-month period from November 1978 to April 1979 Pseudomonas aeruginosa (MDR) resistant to all antibiotics except amikacin was isolated from 15 patients. This organism had not previously been seen in our hospital. Epidemiologic assessment of infected patients revealed that nine of 15 patients had contact either with a previously infected case or contaminated area. All strains of P. aeruginosa were identical by pyocin typing and antibiogram. The organism was present in an environmental reservoir, the urine graduated cylinder, and was found in three of eight receptacles (p = 0.002 vs. other environmental cultures). A case control study of patient risk factors showed aminoglycoside use, other antibiotic use, surgery, intravenous lines, Foley catheter use and mechanical ventilation to be no more frequent in cases than controls. The use of aminoglycosides in only 40% of cases suggests that antibiotic pressure was not the sole factor in perpetuating the epidemic. PMID- 6924647 TI - Transient and resident microflora of burn unit personnel and its influence on burn wound sepsis. AB - The exogenous contamination of a thermally injured patient by contact with the health are team has been a major concern of all burn units. Since the University of Chicago Burn Center routinely monitors each burn injury for sepsis by quantitative bacteriology and recently examined the microbial population present on the hands of the health care team, it was felt that these combined data would shed some pertinent information on exogenous burn wound sepsis. Twenty-nine patients with clinical burn wound sepsis and a bacterial level of greater than 10(5) bacteria/gram of tissue were studied. These patients yielded a variety of microorganisms with P. aeruginosa and Staphylococcus aureus being predominant, followed in incidence by Candida albicans. The resident and transient microflora isolated from each member of the health care team treating the specific individual concerned did not correlate with the causative agent of burn wound sepsis. The most frequent isolate from the staff personnel was Staphylococcus epidermidis followed by Micrococcus species. Though colonization of the thermally injured individual has been reported, these data strongly suggest that colonization is primarily one of an endogenous source rather than that of an exogenous one. PMID- 6924648 TI - Nosocomial ultraviolet keratoconjunctivitis. PMID- 6924649 TI - Grieving and the acceptance of the homosexual identity. PMID- 6924650 TI - Themes and cohesiveness observed in a depressed women's support group. PMID- 6924651 TI - Psychiatric mental health nursing consultation: a two-model system in a general hospital. PMID- 6924653 TI - Anorexia nervosa: framework for early identification and intervention. PMID- 6924652 TI - Anticipatory grief reactions in family members of adult patients. PMID- 6924654 TI - Kallikrein-like activity in salivary glands using a new tripeptide substrate, including preliminary secretory studies and observations on mast cells. AB - The tripeptide substrate D-val-leu-arg-4-methoxy-2-naphthylamine gave a precise localization of reaction product in cryostat sections of aldehyde-fixed salivary glands from a number of species, with Fast Blue B as the capture reagent. In submandibular glands, there was strong staining of the granules in granular tubules of rats and hamsters and somewhat less in mice. Submandibular striated ducts showed variable periluminal staining in a finer granular form; it was abundant in guinea-pigs, strong in cats but somewhat less pronounced in dogs. Parotid glands contained less reactivity with none detectable in hamsters and guinea-pigs. In the rabbit, neither gland showed any reaction. Mast cells were densely stained in glands from cats and dogs; they were less reactive in rats and unstained in the other species. The closely related 7-amino-4 trifluoromethylcoumarin derivative of the tripeptide has been found highly satisfactory for assessing activity in submandibular saliva from cats. Preliminary functional studies indicate that an extensive rapid secretion of enzyme occurs into saliva on sympathetic stimulation, with a corresponding depletion of reactive material from the striated ducts in tissue sections. Far less mobilization of enzyme occurs into saliva on parasympathetic stimulation with no obvious change in the histochemical reaction of striated ducts. The possible significance of these findings in cats is discussed. Extensive qualitative and quantitative studies are required to evaluate enzyme and substrate specificities in each species. Nevertheless, derivatives of D-val-leu arg offer great promise for the functional testing of kallikrein-like reactivity both by histochemical means on cells and biochemically in their secretions. PMID- 6924655 TI - The BF locus and HLA: rare alleles coding for functionally active and inactive factor-B products. AB - The genetic polymorphism of properdin factor B (BF) was studied in different populations. The rarer alleles, BF*F1 and BF*S1, occurred in Caucasians, were less frequent in North American blacks, and were not demonstrated in any of three Oriental populations studied. Two further alleles of BF, termed BF*FM and BF*SM, were found to exist in these populations. The BF*FM allele, which was found only in Caucasians, codes for a functionally inactive factor-B product, whereas the BF*SM allele (found in a single Chinese individual), like other alleles of BF, codes for a functionally active product. HLA haplotype analyses in individuals carrying the rarer alleles of BF revealed not only a strong association between BF*F1 and HLA-B18 and BF*S1 and HLA-Bw50 but an even stronger association between these BF alleles and alleles of the two C4 loci. BF*F1 occurred most frequently on a C4A*3,B*Q0 haplotype, whereas the BF*S1 allele was usually found on a C4A*2,B*1/B*Q0 haplotype. HLA haplotypes carrying the BF*FM and BF*SM alleles all carried the more common C*4A3,B*1 haplotype. PMID- 6924657 TI - "Nuclear" is easier to say than "February". PMID- 6924656 TI - The 5- flanking sequences of Drosophila tRNAArg genes control their in vitro transcription in a Drosophila cell extract. AB - The transcription efficiencies of four Drosophila tRNAArg genes located in a tRNA gene cluster at region 42A on chromosome 2, and containing identical coding sequences, were studied in Drosophila Kc cell extracts. Transcription is modulated by the 5' flanking sequences; efficient transcription is dependent on the presence of an optimal 5' flanking sequence. One of the genes, p17D Arg, is not transcribed in the homologous extract but does compete with the other genes for transcription factors. Deletion of a specific sequence from the 5' flank of the gene of p17D Arg leads to an increase in transcription efficiency. All tRNAArg genes are efficiently transcribed in extracts from HeLa cells. However, introduction of small amounts of Drosophila extract reduces the efficiency of transcription in HeLa extracts. This is due to incompatibility between transcriptional components of the two extracts. PMID- 6924658 TI - The pride and the passion. PMID- 6924659 TI - Ileal-anal reservoir: an alternative to permanent ileostomy. PMID- 6924660 TI - An interdisciplinary audit to justify enterostomal therapy services. PMID- 6924661 TI - How to plan an ostomy workshop. PMID- 6924662 TI - Exstrophy of the bladder. PMID- 6924663 TI - Stoma site selection. PMID- 6924665 TI - A method for pouching large, draining abdominal wounds. PMID- 6924664 TI - Persistent peristomal skin reaction: a case of psoriasis. PMID- 6924668 TI - The nursing management of patients with long-term indwelling catheters. AB - A survey of 107 hospitalized and home-based patients showed up considerable variations in nursing management of indwelling catheters. CSU records of hospitalized patients showed a wide range of infecting organisms. Antibiotic treatment was found to be unimportant. Three types of male Foley catheter were in general use: 100% silicone, silastic and latex with teflon-treated coatings. Difficulties were reported in obtaining the 100% silicone catheters. Sixty-eight per cent of the patients used leg bags and the drainage bag supporting systems in use were felt to be inadequate. Catheter bypassing was a problem for 40% of the patients. Nurses adopted many procedures to cope with bypassing. Results show that some patients were needlessly catheterized. The study emphasizes the need for further investigations and better policies for management of long-term catheters. PMID- 6924666 TI - The person behind the counter. PMID- 6924669 TI - The Norton score: an early warning of pressure sores? AB - This paper investigates the predictive power of the Norton score in the problem of anticipating pressure lesions, and looks at some variants on that score. The Norton score is now nearly 20 years old but is still not in frequent use by nurses, and has been the subject of little research, especially in its predictive ability. By following the progress of two matched samples over a 15-month period in a district general hospital it is established that the Norton score does perform at least as well as a number of reasonable variants of it, and that in particular the physical score and incontinence score are the crucial elements. A follow-up sample in which the variants are retested confirms the usefulness of the Norton score. PMID- 6924667 TI - Osto-Zyme. PMID- 6924670 TI - Reality orientation for the elderly: a critique. PMID- 6924671 TI - Nursing decision making in critical care areas. AB - This exploratory study sought to identify factors that critical care nurses consider relevant in making rapid patient care decisions; to explore the decision making of these nurses in crisis situations; and to identify critical patient care situations where rapid nursing decisions are made. The convenience sample consisted of 50 nurses in critical care settings. A semi-structured interview with a critical care case study was utilized to examine the nurses' decision making. Open ended responses were transformed into fixed categories for tabulation. The findings suggested that: 1 knowledge and experience were the most important factors influencing rapid decision making; 2 although the nurses identified the appropriate decisions in a given crisis situation they had difficulty providing a theoretical rationale for their decisions; 3 the given case study and the 50 crisis situations identified by the subjects indicated that many nursing decisions for critically ill patients were carried out prior to physician assistance. A demographic data questionnaire that examined age, nursing experience, formal education and continuing education of the subjects determined that the majority of the nurses were under 30 years old, had either less than 1 year experience or 7-9 years in critical care, were graduates of a 2-year diploma programme, and took continuing education courses at the community college level. PMID- 6924672 TI - Nursing models and research--a restricting view? AB - The question is asked, Do some nursing models present a restricting view? If so, then the type of research in nursing may be restricted also. The author examines the writings of several nurse theorists to demonstrate the development of a singular focus, the patient. This consideration is followed by an introduction of the thoughts of critics on the narrow perspective embraced by some nurses. Blind acceptance of any nursing model is questioned. The use of a model must be accompanied by discussion, exploration and adaptation. No one model provides a true picture for all nursing situations. PMID- 6924673 TI - New perspectives on nursing lower limb amputees. AB - New perspectives on nursing lower limb amputees arise from the author's researches into amputee rehabilitation and a summary of other recent research findings. These are dealt with in the context of basic amputee treatment and the nursing process. There is new material on the psychological and neurological sequelae of amputation, the practical problems of loss of a limb and the prosthetic dimension of treatment. The patients' reactions to lower limb amputation were found to vary from intense grief to intense relief, many noting it to be of minor or moderate consequence. The model of sudden and shocking loss is largely incorrect. Attention is drawn to an unrecognized ordinariness which should become part of amputee nursing. Patients have many practical problems. These are social and economic, personal and domestic. The ward environment is unsuited to these needs but, working closely with therapists, nurses can do much to facilitate amputee rehabilitation. The modern purpose of amputation surgery is prosthetic replacement. Nurses should be working with some urgency towards uniting patient and prosthesis. Pain and discomfort are underestimated and research shows them to be a major characteristic of amputation continually and for many years after surgery. A variety of pain syndromes are involved. PMID- 6924674 TI - Learning to nurse: the family as the unit of care. AB - How can we prepare nurses who will have as their focus of practice, the health of the family unit? This paper describes the learning outcomes which were generated from a short term experience in a curriculum where the major thrust is learning to nurse families in a health promoting way. Students were provided with experience with families who were undergoing an important family event, e.g., coping with the short term hospitalization of a child. An exploration and analysis of these experiences revealed for students the content of nursing families who are in the process of dealing with this particular event of family living. This content related to the acquisition of nursing skills of an interpersonal, technical and decision-making nature as well as the development of knowledge which provides the basis for nursing the family as the unit of care. PMID- 6924675 TI - Patient centered teaching: a future role for the psychiatric nurse teacher? AB - It was suggested by Reynolds & Cormack (1982), that psychiatric nursing skills could be taught more realistically, if there was a greater concentration of teaching resources in the clinical areas, in order to make fuller use of the learning opportunities to which learners are exposed. They expressed the view that this was essential in order to clarify the psychiatric nurse's role and to shift the emphasis of psychiatric nurse education away from psychomotor skills to interpersonal skills. This paper describes a trial teaching programme which was designed to gain access to, and utilize, 'live' patient centered teaching opportunities in the clinical area more effectively. It involved the writer and four nurse learners, who were allocated to a long-term ward during a 12-week psychiatric nursing module within a comprehensive modular system of nurse training. The main teaching method involved structured interaction with the patients. PMID- 6924676 TI - Patient satisfaction with community psychiatric nursing: a prospective controlled study. AB - A sample of patients allocated to receive either community psychiatric nursing or out-patient psychiatrist follow-up was interviewed at 6-month intervals for a total period of 18 months. Two dimensions of patient satisfaction are discussed: a cross-sectional analysis of the quality of the perceived therapeutic relationship and an analysis over time of attitudes to aspects of the mental health care received. The satisfaction expressed with elements of the therapeutic relationship revealed that patients find nurses more approachable and more sympathetic. The satisfaction expressed by patients receiving the nursing mode of follow-up was superior to that expressed by out-patient psychiatrist patients. Particularly positive were responses made by nursing patients to domiciliary visiting. The greater levels of satisfaction with nursing follow-up increased over time. PMID- 6924679 TI - Who are the certified gerontological nurses? PMID- 6924677 TI - Attitudes of 2325 active and inactive nurses to aspects of their work. AB - As a part of an ongoing larger study concerned with nurse manpower planning, an attempt has been made to investigate the reasons for the non-participation in the labour force of such a large proportion of qualified nurses. In an attempt to collect information on this topic a questionnaire was developed and distributed to a sample of nurses. The article describes in some detail the two different ways in which the names and addresses of the sample were generated. The first method involved making contact by the simple expedient of dropping leaflets through letterboxes while the second involved tracing respondents through their last known address when they originally qualified. The success of these two approaches is contrasted which should be of value to anyone contemplating a similar name-capturing exercise. A total of 2325 questionnaires were returned and computer analysed. This article presents the results of one part of that analysis i.e. the factor analysis conducted on the attitudinal questions contained in the document. A five-factor solution yielded highly interpretable results and the factor loadings are presented along with the pattern of responses. The factor scores are then contrasted for three different groups of respondents: the grouping being based on whether the respondent was working full-time, part-time or not at all. PMID- 6924678 TI - Nursing practice, standards and accountability. PMID- 6924680 TI - A double-edged sword: ageism and sexism. PMID- 6924681 TI - Gray and gay. PMID- 6924684 TI - [Physiological and pathological significance of plasma prekallikrein in obstetrics]. AB - Plasma kallikrein acts as a chemical mediator of microcirculation and as a contracting agent of smooth muscle by liberating bradykinin from high molecular weight kininogen. In addition, prekallikrein relates to coagulation process of blood. It is, therefore, a intriguous problem to know the behavior of prekallikrein in obstetrics, especially as to the mechanisms of labor, edema of toxemia and DIC. The following results were obtained: 1) Plasma prekallikrein determined by chromogenic tripeptide substrate was increased with advance of gestational ages, and reached maximum (213.5 +/- 31.1%) at the term. At the beginning of labor, the prekallikrein level was suddenly decreased, and remained low during labor. Rapidly lowered plasma prekallikrein during labor seems to be result from consumption of prekallikrein due to conversion to kallikrein. The kallikrein probably relates to uterine contraction by forming bradykinin. 2) A lowered plasma prekallikrein level was observed in 29 cases of toxemia, especially in edema type. In toxemic cases, kallikrein may play an important role in producing edema by bradykinin. 3) In 16 cases of DIC, prekallikrein was significantly low (p less than 0.001) especially in cases of endotoxic shock, suggesting consumption of prekallikrein as in other various coagulation fibrinolysis factors in DIC. PMID- 6924682 TI - "We had no choice". A study in familial guilt feelings surrounding nursing home care. PMID- 6924683 TI - Olde is not a four letter word. PMID- 6924685 TI - Nursing care in the evaluation of the epilepsy surgery candidate. AB - The Epilepsy Surgery Program at the Veterans' Administration Medical Center is designed to surgically treat specific individuals with intractable epilepsy. A thorough workup encompassing several months ensures the appropriateness of each candidate. Members of the evaluating health team include nursing, neurology, neurosurgery, neuropsychology, psychiatry, and neuroradiology. In order to progress to surgery, the candidate must be physically, psychologically, and socially healthy within the limits of a developed criteria. PMID- 6924686 TI - Tremors: associations and assessment. PMID- 6924687 TI - The extrapyramidal nervous system. PMID- 6924690 TI - Using metrizamide for lumbar myelography: adverse reactions and nursing implications. PMID- 6924688 TI - Normal pressure hydrocephalus in the parkinsonian patient. PMID- 6924691 TI - Conceptual frameworks for clinical practice. AB - The patient with neurologic dysfunction is confronted with an enormous challenge. First, he/she is faced with the physiologic and psychological changes associated with the condition. Secondly, this individual may require hospitalization, which demands adaptations in his/her self-concept and family roles and responsibilities. Thirdly, treatment of the dysfunction may necessitate long-term medical management which would challenge his/her self-care abilities and the functioning of the family system. The concepts of body image, self-concept, self care, and family systems have been synthesized into a conceptual framework relevant to patient populations experiencing neurologic/neurosurgical problems. This conceptual framework provides a structure which can be utilized to explain the reactions and behavior of patients, formulate generalizations relevant to this population, and develop and test clinical protocols. Individual nurses interacting with neurological/neurosurgical patients need to utilize this conceptual framework to develop and test clinical protocols that are pertinent to their own unique clinical situation. Communication of the results of this process will foster the expansion of the scientific knowledge base for clinical practice. PMID- 6924692 TI - Placement of umbilical artery catheters: high vs. low. AB - Placement of umbilical artery catheters was retrospectively reviewed in 181 newborns to evaluate random placement of catheter tip in the "high" position between T7 and T9 in the thoracic aorta of 127 infants and in the "low" position below L3 in the abdominal aorta of 54 infants. Group differences in gestational age, asphyxia, hypotension, respiratory disease, duration of catheterization, or infusate type were not significant. Cyanosis or blanching in the low extremities occurred in 67% of the "low" group and 21% of the "high" group (P less than .001). Hematuria occurred in 39% of the "low" group and 21% of the "high" group (P less than .05). High placement appears to have fewer complications. Prompt intervention by neonatal nurse practitioners can help reverse complications that occur during umbilical artery catheterizations. PMID- 6924694 TI - Selected maternal-infant care practices of Spanish-speaking women. AB - To ascertain which postpartum maternal-infant care practices were prevalent in a large southern California hospital's Spanish-speaking population, an informal survey was taken of 30 Hispanic women. The survey consisted of an initial interview in the hospital and a second interview in the patient's home. The latter interview covered seven open-ended questions regarding umbilical cord care and "La Cuarentena" practices. Results from the small survey suggest that cultural practices are observed by Hispanic women. Nursing implications for those working with Spanish-speaking patients are discussed. PMID- 6924689 TI - Regional cerebral blood flow: patient correlations. PMID- 6924695 TI - Comprehensive assessment of the healthy gravida. PMID- 6924696 TI - Informed consent: client participation in childbirth decisions. AB - In recent years, there has been a tremendous rise in public consciousness concerning patients' rights. Previously, patients relied upon the expertise of health-care providers, but now it is more common for patients to seek active involvement in the decision-making process affecting their care. The patient's right to self-determination is central to the decision-making process between the client and the provider. A patient's right to autonomy, therefore, imposes an obligation upon the health-care provider to obtain informed consent from the obstetric client. PMID- 6924693 TI - Demand vs. scheduled feedings for premature infants. AB - To compare the effects of demand and schedule feeding in premature infants who weighed less than 2500 grams at birth and who were appropriate for gestational age, 36 premature infants were studied. Premature infants were assigned randomly to either demand (N = 18) or scheduled (N = 18) feedings in a regional NICU in a metropolitan hospital. Infants that were allowed to feed on demand took amounts of formula and calories similar to those infants who were fed specified amounts of formula every three or four hours. Demand-fed infants were bottle-feeding well enough to be discharged earlier than schedule-fed infants, required fewer feedings per day, and needed fewer gavage feedings. No complications related to feedings were seen in either group. PMID- 6924697 TI - Preoperative teaching on a gynecology unit. PMID- 6924698 TI - Moral authority in OGN nursing. AB - Ethical dilemmas are becoming more common in the work of the OGN nurse. Ethical decisions that involve nurses sometimes appear as traps in which nurses can feel coerced or manipulated. Nurses may overplay, underplay, or ignore their professional authority due to miscommunication or misunderstanding. A careful reassessment of personal values and assumptions about the OGN nurse's role and responsibility in decision making must be made. PMID- 6924699 TI - Evaluation process omitted. PMID- 6924700 TI - Contract orientation for the intravenous nurse. PMID- 6924702 TI - Hyperbaric medicine. PMID- 6924703 TI - Nursing techniques in preparing and administering intravenous admixtures. PMID- 6924701 TI - The status of intravenous therapy education in Associate Degree nursing programs. PMID- 6924705 TI - The current state of intravenous therapy nursing in Britain. PMID- 6924704 TI - Use of hydrochloric acid in metabolic alkalosis. PMID- 6924706 TI - Self assessment in intravenous therapy. PMID- 6924708 TI - Approved oncology drugs in Spartanburg General Hospital. PMID- 6924707 TI - Placement of I.V. teams in hospitals. PMID- 6924709 TI - Chemotherapy waste disposal: a safe and practical method. PMID- 6924710 TI - Making the NITA standards work for you. PMID- 6924711 TI - Orientation program for an outpatient infusion center. PMID- 6924712 TI - Blood components and transfusion reactions. PMID- 6924713 TI - Cost quality and staffing considerations for I.V. teams. PMID- 6924714 TI - Phlebitis, infections, and filtration. PMID- 6924716 TI - The concept of individualized care in nursing practice. PMID- 6924715 TI - How to do a "definitive" study. PMID- 6924718 TI - Theory Z management: can it work for nursing? PMID- 6924717 TI - Collaboration in students: how can we improve it? PMID- 6924719 TI - Supply and demand relations and the shortage of nurses. PMID- 6924720 TI - What job stress means for the staff nurse. PMID- 6924722 TI - Why nurses leave nursing: a survey of former nurses. PMID- 6924721 TI - Burnout in nursing--what it is and how to prevent it. PMID- 6924723 TI - Effective use of the nursing clinical career ladder through career development. PMID- 6924724 TI - On the scene: Saint Joseph's Hospital. Shared governance in nursing. PMID- 6924725 TI - The career concept in nursing. PMID- 6924726 TI - Automation and staff nurses' patient management activities. PMID- 6924727 TI - Looking for empathy. PMID- 6924729 TI - Abdominal aortic aneurysm? This patient takes AAA care. PMID- 6924730 TI - Fear of floating to a renal unit. PMID- 6924731 TI - Giving Jane our best care was the worst thing for her. PMID- 6924732 TI - Want to get your patient involved in his care? Use a contract. PMID- 6924733 TI - A neurologic assessment procedure that won't make you nervous. PMID- 6924735 TI - Caring for the severely handicapped newborn: Brian. PMID- 6924734 TI - Myocarditis. PMID- 6924737 TI - Deciphering diagnostic studies: pancreatic enzymes. PMID- 6924736 TI - Caring for the severely handicapped newborn: Petey. PMID- 6924739 TI - Test your knowledge of adult health problems. Part 2. PMID- 6924738 TI - This new type of I.V. dressing can save you time. PMID- 6924741 TI - Stepmothers as first-time parents: their needs and problems. PMID- 6924742 TI - Postural therapy at home for infants with gastroesophageal reflux. PMID- 6924740 TI - Streptococcal pharyngitis: a persistent challenge. PMID- 6924743 TI - Knowledge and breast-feeding practices among nurses and teachers in Ile-Ife, Nigeria. PMID- 6924744 TI - Motherhood, culture, and change. PMID- 6924745 TI - Bonding as perceived by mothers of twins. PMID- 6924748 TI - Practice management. Reimbursement basics. PMID- 6924747 TI - Pediatric management problems: ataxia. PMID- 6924746 TI - Behavioral techniques in teaching hemophilia factor replacement procedures to families. PMID- 6924749 TI - Changes of post-transcriptional modification of wye base in tumor-specific tRNAPhe. AB - Nucleotide sequences of normal mouse liver tRNAPhe and tumor-specific tRNAPhes isolated from Ehrlich ascites tumor and neuroblastoma cells were examined by post labeling techniques. The results showed that their sequences are identical, except for changes in post-transcriptional modifications that are located in the anticodon region. Normal mouse liver tRNAPhe contained Cm32, Gm34 and YOH37. On the other hand, tumor-specific tRNAPhes were found in one of two possible configurations: 1) Cm32, Gm34 and Y*OH37 (under-modified YOH) or 2) C32, G34 and m1G37. The ratio of the two forms of tRNAPhes differed in different tumor cells; Ehrlich ascites tumor tRNAPhe had mainly Y*OH-containing tRNAPhe whereas neuroblastoma tRNAPhe has predominantly m1G-containing tRNAPhe. It was concluded that tumor-specific tRNAPhes are products of different extents of modification, rather than of new tRNA transcription. PMID- 6924751 TI - Systems of life No 95. Systems and signs: locomotor system - 1. Head, neck & shoulders. PMID- 6924750 TI - Protein synthesis in rabbit reticulocytes: characteristics of CO-eIF-2 protein complex. AB - A high molecular weight reticulocyte protein factor, named Co-eIF-2, contains Co eIF-2A, Co-eIF-2B, and Co-eIF-2C activities and stimulates Met-tRNAf binding to eIF-2 both in the presence and absence of Mg2+. Some characteristics of this stimulation in the absence of Mg2+ are: (1) Stimulation is most pronounced at low eIF-2 levels. (2) Stimulation is partially resistant to heat and NEM treatment, and thus appears to be due to the combined action of both heat and NEM insensitive Co-eIF-2A, and heat and NEM-sensitive Co-eIF-2C activities. (3) [3H]GDP bound in eIF-2 . [3H]GDP complex is rapidly displaced by unlabelled GTP during ternary complex formation Co-eIF-2 stimulates Met-tRNAf binding to eIF-2 even when added after the [3H]GDP from eIF-2 . [3H]GDP has been completely displaced. This indicates that Co-eIF-2-stimulation is not due to GDP displacement from eIF-2 . GDP. We propose that eIF-2 molecules become inactive in the presence of Mg2+ and at high dilution, and Co-eIF-2 restores the inactive eIF 2 molecules into an active form. PMID- 6924752 TI - Guidelines for studying and working abroad. 3. Employment conditions and contract checklist. PMID- 6924753 TI - Research - how can we challenge nursing practice? PMID- 6924754 TI - Making the right choice. Interview by Laurence Dopson. PMID- 6924757 TI - Shared care and infection in a special care baby unit. PMID- 6924755 TI - Professional attributes. The Radical Nurses Group. PMID- 6924756 TI - Nursing care study: intensive care following cardiac arrest. PMID- 6924758 TI - A cancer screening and detection programme in Texas. PMID- 6924759 TI - The nurse practitioner at work. 2. The American experience. PMID- 6924760 TI - Dumping for dyspepsia? PMID- 6924761 TI - Emotional pain in dying patients and their families. PMID- 6924762 TI - The use of incontinence underpads in hospital. PMID- 6924763 TI - A taste of things to come. 1. Aiming for the stars. 2. From the inside out. PMID- 6924764 TI - Nursing care study: hindquarter amputation. PMID- 6924765 TI - New trends in endometrial cancer. PMID- 6924766 TI - Breakdown: commonsense psychiatry for nurses. 2. The affective disorders. PMID- 6924768 TI - The nurse practitioner at work. 3. Clinical practice. PMID- 6924767 TI - Stress and the postnatal care of women. PMID- 6924770 TI - Could you care more? Reflections. PMID- 6924769 TI - Setting up a CSSD service. PMID- 6924771 TI - An experimental role-based training scheme for SNOs. PMID- 6924772 TI - Wound care No. 15. Penetrating wounds of the chest and abdomen. PMID- 6924773 TI - Words apart in the NHS. PMID- 6924774 TI - Labour relations. PMID- 6924776 TI - Selectron treatment in gynaecology. PMID- 6924777 TI - Developing nurse managers: a practical approach. PMID- 6924775 TI - Nursing care study: self-neglect--a challenge for nursing. PMID- 6924780 TI - Of cabbages--and eggs? PMID- 6924778 TI - Patterns of dying. PMID- 6924781 TI - Symposium on oncologic nursing practice. PMID- 6924779 TI - Cerebral haemorrhage--a patient's view. PMID- 6924782 TI - Assessment of the adult with cancer. AB - The nursing process is a systematic method of problem-solving that incorporates four phases: assessment, planning, intervention, and evaluation. These four steps, in actual practice, are continuous and cyclical. One may not be able to complete the entire data-gathering phase and then move on to the planning phase. For example, the nurse often finds it necessary to obtain a baseline assessment, plan for immediate care to meet priority needs, and then collect additional information at a later time to set goals for less pressing problems the patient may experience. Changing conditions and alterations in the patient's status requires continual reassessment and modification of approaches. PMID- 6924783 TI - Care of the patient receiving antineoplastic drugs. AB - Caring for patients who receive chemotherapeutic agents is among the most challenging and potentially rewarding dimensions of oncologic nursing practice. The nurse must possess sound knowledge of not only the biologic and behavioral sciences, but also of current oncologic nursing practices, pathology, and the pharmaceutics of antineoplastic drugs. However, comprehensive nursing care must counterbalance clinical expertise with sensitivity to the unique problems patients with cancer and their families experience. Because the nurse is often the only health care professional with whom the patient and family have consistent contact, clinical expertise and sensitivity are of critical importance to the well-being of patients and their families during therapy. Through accurate, ongoing assessment and identification of problems, prompt recognition of learning needs, and intelligent, supportive, and creative interventions, nurses can do much to assure that patients and families receive the comprehensive care to which they are entitled. It is the purpose of this paper to discuss essential aspects of antineoplastic drug therapy and the important role of the nurse in caring for patients receiving this type of treatment. PMID- 6924785 TI - Home management of the adult patient with leukemia. AB - The many changes that have occurred within the medical profession and among the public are taking long-term care out of the hospital and placing it back into the home. Attitudes toward cancer have altered, as seen by the rapid growth of the oncology specialty as well as the willingness of the community to allow those with cancer to return to a viable status. Even the individual who must face end stage disease can now rest comfortably in the privacy of his or her own home, surrounded by loved ones. Improved nutritional efforts during periods of active therapy are reducing the side effects and improving the tolerance of highly cytotoxic drugs. Thus, acute episodes of treatment are shortened, allowing for earlier discharge. Individuals are demanding accurate information regarding their disease and its treatment. Patients are catalysts for their own recovery as they become more active participants in their care. Some are even choosing not to undergo suggested therapies and are returning home to put their lives in order and let disease processes take their natural course, even until death. As for leukemia, more supportive measures such as blood component therapy and evaluative work-ups are being offered on an outpatient basis. Patients are learning self care measures to counteract or minimize side effects to chemotherapy or radiation therapy. Thus, overwhelming infection is of less risk and hospitalization is shortened. Infection, especially from Staphylococcus aureus, still remains a major cause of death of patients with leukemia. However, one must consider how prevalent this organism is in the hospital environment. Home care management is improving; care can be as comprehensive as one might need or receive in the hospital setting. PMID- 6924784 TI - Care of the patient receiving radiation therapy. AB - External radiation therapy, or teletherapy, is the use of ionizing radiation to destroy cancer cells. Clinical use of ionizing radiation as treatment for cancer began with the discovery of x-rays in 1895, the identification of natural radioactivity (radium) in 1896, and the first reported cure of cancer, a basal cell epithelioma, induced by radiation in 1899. Initially, radiation was administered as a single large dose and produced severe, life-threatening side effects. The basis for the use of ionizing radiation in daily increments for a period of weeks was provided by Regaud in 1922; ten years later, Coutard clinically developed the method of dose fractionation, which remains in use today. Although the use of ionizing radiation as a treatment is over eighty years old, only in recent years have advancements in its clinical application been based on research related to the biologic effect of radiation on human cells. To effectively care for the patient prior to, during, and at the completion of external radiation therapy, the nurse must know the physical and biologic basis of external radiation therapy and its clinical application. PMID- 6924786 TI - Cancer pain: you can help! AB - Pain exists because electrical impulses travel along a series of nerves from "where it hurts" through the gate in the spinal cord and through the thalamus to the areas of the brain where thinking, feeling, and action are controlled. Along this path are several "switches" that can adjust the pain, or turn it down as one would the volume of a radio. Figure 5 summarizes the interventions that have been discussed in this article in relation to these four switches. One can use a moderate to large amount of a single intervention (such as medication) to shut off the pain; or one can use small to moderate amounts of a combination of interventions to accomplish the same or greater level of comfort. In most situations, a combined approach provides the patient with better control of pain, a more active role in his care, fewer side effects, and less dependence on others. PMID- 6924787 TI - Psychosocial adaptation of the adult with cancer. PMID- 6924788 TI - Patient education: the adult with cancer. PMID- 6924789 TI - The clinical nurse specialist in oncology. PMID- 6924790 TI - The impaired resolution. PMID- 6924792 TI - Discussion of consultant/advocate for the medically ill hospitalized patient. PMID- 6924791 TI - Consultant/advocate for the medically ill hospitalized patient. PMID- 6924793 TI - The right to die: in support of passive euthanasia. PMID- 6924796 TI - Creative nursing is where you find it: evolution of a unique nursing clinic. PMID- 6924794 TI - Who and where are nursing's historians? PMID- 6924795 TI - The therapeutic effect of faith. PMID- 6924797 TI - Why creativity in nursing? PMID- 6924798 TI - Power, leadership, and nursing. PMID- 6924800 TI - The effect on nursing students of direct-care experience with death and dying. PMID- 6924799 TI - Hospital-based "on-call" nurses vs. outside contract nurses: a creative approach to cost and quality control. PMID- 6924802 TI - OR computers: the future is today. PMID- 6924801 TI - Radioisotopic measurement of plasma kallikrein. PMID- 6924803 TI - With pen in hand. PMID- 6924804 TI - The threat of talc on surgical gloves. PMID- 6924805 TI - OR students are people too. PMID- 6924806 TI - Interview: Edwina A. McConnell. PMID- 6924808 TI - [Activity of the blood kallikrein-kinin system in different forms of newly detected pulmonary tuberculosis]. PMID- 6924807 TI - A lesson in compassion. PMID- 6924809 TI - [Status of the blood kallikrein-kinin system in diabetes mellitus]. PMID- 6924810 TI - Teaching research in nursing: issues and strategies. PMID- 6924811 TI - Conceptual mapping: development of the strategy. PMID- 6924812 TI - An overview of theory and research related to space use in hospitals. PMID- 6924813 TI - Professionalism, work ethic, and empathy in nursing: the nurse self-description form. PMID- 6924814 TI - More than skin deep: relationship between perceived physical attractiveness and nursing students' assessments. PMID- 6924815 TI - Ethical issues in nursing research. PMID- 6924816 TI - Strategies for teaching nursing research: coping with the "dry well" syndrome. PMID- 6924817 TI - [Determination of factor XII and plasma prekallikrein with chromozym PK]. PMID- 6924819 TI - Education--past, present, and future. Third Annual Carole de Mille Lecture. PMID- 6924818 TI - Primary enzyme quantitation using substrates labeled with a second indicator enzyme. I. Elastase determination using peroxidase-labeled elastin. PMID- 6924820 TI - Customizing infection control educational programs within the health care facility. Meeting a challenge vs. just satisfying a requirement. AB - Infection control practitioners working within health care facilities are charged with the providing of in-service education programs for all new employees and volunteers as well as for all hospital departments, at least annually. To be effective, each program should be customized to meet the needs of the group for which it is given. Such a charge may be viewed as simply a "requirement that must be satisfied," or it may be approached as a challenge to be met with a measure of ingenuity and inventiveness. Academic preparation in the principles and skills germane to teaching are traditionally lacking in the training of health care professionals, and the ICP is thus left accountable for a job function for which she/he may have little proficiency. Customized education programs may be achieved with thoughtful planning and through the use of a few innovative ideas and resource materials available to most practitioners. PMID- 6924821 TI - Overwhelming infection in a cancer patient caused by Arizona hinshawii: its relation to snake pill ingestion. PMID- 6924822 TI - Infection control and employee health: epidemiology and priorities for program development. PMID- 6924823 TI - Hydrogen peroxide warrants careful consideration for control of catheter associated bacteriuria. PMID- 6924824 TI - Evaluation of the Cathra inoculating device for susceptibility testing of methicillin-susceptible and methicillin-resistant Staphylococcus aureus strains. AB - We compared the antimicrobial susceptibility results obtained with the Cathra replicator and reference methods when Staphylococcus aureus strains were tested by using agar dilution techniques. The Cathra replicator and the 0.001-ml calibrated loop gave results that fell within +/- 1 log2 dilution for greater than or equal to 95% of isolates when methicillin and cefamandole were tested. PMID- 6924826 TI - What changes will OR nurses face in the year 2000? PMID- 6924825 TI - Synergism between vancomycin and gentamicin or tobramycin for methicillin susceptible and methicillin-resistant Staphylococcus aureus strains. AB - By the time-kill curve method, the combinations of vancomycin-gentamicin and vancomycin-tobramycin were shown to be synergistic against a majority of methicillin-susceptible and -resistant strains of Staphylococcus aureus. PMID- 6924827 TI - Development of process-oriented criteria to monitor perioperative nursing. PMID- 6924828 TI - Development of process-oriented criteria to monitor perioperative nursing. 1. The project. PMID- 6924829 TI - Development of process-oriented criteria to monitor perioperative nursing. 2. Results of clinical testing. PMID- 6924831 TI - Development of process-oriented criteria to monitor perioperative nursing. 4. Reflections from research participants. PMID- 6924830 TI - Development of process-oriented criteria to monitor perioperative nursing. 3. Issues in perioperative nursing practice. PMID- 6924832 TI - Advances in surgical tourniquets. PMID- 6924833 TI - Salespeople can increase your expertise. PMID- 6924834 TI - Patching wrappers: can you vs should you. PMID- 6924835 TI - [Effect of the stimulators and inhibitors of the central dopaminergic structures on the kininogen level and kallikrein activity in the rat plasma]. PMID- 6924836 TI - The changing climate of nursing. PMID- 6924838 TI - Dietary guidelines for Australians: bread and water? PMID- 6924837 TI - The nurse and the law. Mailbag. PMID- 6924839 TI - After Nightingale: a preliminary report of work undertaken by nurses in Queensland. PMID- 6924840 TI - Full-time, part-time: a study of opinions. PMID- 6924841 TI - Domestic violence against women: the role of health professionals. PMID- 6924844 TI - Our medicine isn't magic. PMID- 6924845 TI - Technological demands on the midwife of the future. PMID- 6924843 TI - First aid training for the blind. PMID- 6924846 TI - Educating the midwife for the challenge of the 21st Century. PMID- 6924842 TI - The Matthew Davey case - the death of a small boy following elective surgery. PMID- 6924848 TI - Expanding horizons of nursing practice. PMID- 6924847 TI - Social trends and their influences on health. PMID- 6924849 TI - Preparation of nurses for the future. PMID- 6924850 TI - Professional integrity and medico-moral codes. PMID- 6924851 TI - Morality of contraception. PMID- 6924852 TI - Health Care Workers Action Movement. PMID- 6924853 TI - Evaluation of instructional medical materials containing minority group-related information. PMID- 6924854 TI - How much vitamin C should I take. PMID- 6924855 TI - A comparison of the catalytic activities of human plasma kallikreins I and II. AB - Subsites in the S2-S4 region [Schechter & Berger (1967) Biochem. Biophys. Res. Commun. 27, 157-162] were identified in human plasma kallikrein II (EC 3.4.21.8). Kinetic constants (kcat, Km) were determined for a series of seven extended N aminoacyl-L-arginine methyl esters based on the C-terminal sequence of bradykinin (-Pro-Phe-Arg) or (Gly)n-Arg. With these substrates it was found that deacylation of the enzyme was rate-limiting. It was possible to infer that L-proline at residue P3 interacted with subsite S3 of the enzyme and L-phenylalanine at residue P2 interacts hydrophobically with subsite S2 in addition to hydrogen bonded interactions with this subsite region. By comparison with the results of a similar study with human plasma kallikrein I, it is observed that although broadly similar subsite interactions occur between the two enzyme forms, the rate of deacylation of kallikrein II is approx. 35% of that observed for kallikrein I, and the latter form is up to ten times more active (in terms of kcat./Km) than kallikrein II. PMID- 6924856 TI - Near ultraviolet circular dichroism spectroscopy of plasma fibronectin and fibronectin fragments. PMID- 6924857 TI - Human platelet aggregation induced by 1-alkyl-lysophosphatidic acid and its analogs: a new group of phospholipid mediators? PMID- 6924859 TI - Basic proline-rich proteins from human parotid saliva: complete covalent structure of protein IB-9 and partial structure of protein IB-6, members of a polymorphic pair. AB - The complete amino acid sequence of a basic proline-rich protein, IB-9, from human parotid saliva was determined by automated Edman degradation of peptides obtained by enzymatic cleavage of the intact protein with clostripain. The protein was digested with papain and elastase to obtain overlapping peptides. Automated Edman degradation of the intact protein was also performed. The protein consists of 61 amino acids, of which 26 are proline residues. The partial sequence of another human parotid basic proline-rich protein, IB-6, was also obtained. With one exception the first 54 residues of the two proteins are identical. An exceptional degree of internal reiteration occurs in both molecules, including several repeated sequences of 12-14 amino acids. The proteins show a high degree of homology with the C-terminal portion of the salivary acidic proline-rich protein C. PMID- 6924860 TI - Selenium-containing tRNAs from Clostridium sticklandii. Cochromatography of seleno-tRNA I with L-VALYL-tRNA. AB - It has been previously shown that Clostridium sticklandii specifically synthesized three readily separable 75Se-labeled tRNAs, designated seleno-tRNAs I, II and III, and the partially purified seleno-tRNA II cochromatographed with L prolyl-tRNA on DEAE-Sephadex A-50 (Chen, C.S. and Stadtman, T.C. (1980) Proc. Natl. Acad. Sci. U.S.A. 77, 1403-1407). In the present study a highly purified 75Se-labeled tRNA I was obtained by chromatography on benzoylated DEAE-cellulose, DEAE-Sephadex A-50 and Sepharose 4B. The 75Se-labeled tRNA I cochromatographed with an L-valine-accepting species on DEAE-Sephadex A-50 and Sepharose 4B. Addition of a 285-fold molar excess of unlabeled L-valine to the L-valine acceptor activity assay mixture markedly decreased the amount of L-[14C]valine bound to seleno-tRNA I. PMID- 6924858 TI - [Studies on cerebral scavenger cells (fluorescent granular perithelial cells) - especially uptake and digestion of incorporated fat]. AB - Small cerebral vessels including capillaries are provided with the specific barrier (blood brain barrier) for a transport of substances from blood to cerebral tissue. However, it is also established that fat soluble substances are easily permeable in this barrier. Along cerebral small vessels, the cells having intracellular fluorescent granules are distributed and named "fluorescent granular perithelia (F.G.P.)" by the authors. They are potent in the uptake capacity for exogenous substances as reported in the previous papers. In this study, 24 male Wistar rats aged 8 months and 2.5 years old were employed. They were fed with a fat rich chow (Oriental Co.) containing 10% lard, 2% cholesterol and methylthiouracil for one day and fifteen days. Half of them was subcutaneously injected with 5 mg/kg of elastase (Eisai Co.) dissolved in physiological saline once a day. To clarify the effect of elastase on fat incorporated by F.G.P., 4 rats aged 2.5 years were fed with a fat rich chow for 2 days. After then, they were fed with ordinal rat chow for 3 days with or without elastase injection. After decapitation, cerebral cortex of rats was removed in cold physiological saline and sliced with a blade. Half of the sliced specimens was prepared by the authors' method (Mato and Ookawara, 1979) and stained with hematoxylin eosin, periodic acid Schiff reaction and sudan black B for a light microscopical observation. The other half of the specimens was immersed in a mixture containing 2% paraformaldehyde and 2.5% glutaraldehyde buffered with 0.1M phosphate solution (pH 7.4) for 10 h. The specimens were then postfixed with osmium tetroxide buffered with the same solution for 2h. The other procedures for embedding and cutting were the same as in a routine method. Following findings were obtained at the light and electron microscopical levels; when they were fed with a fat rich chow, fat in blood passed through vascular walls and was taken up by F.G.P.. The quantity of fatty deposits in F.G.P. was different depending on age of rats employed for the experiment. The deposits in F.G.P. increased with advancing of age. That is, in old rats a lot of deposits were chiefly distributed in inclusion bodies at one and fifteen days after the administration. The difference in quantity of deposits between young and old rats was not only based on the permeability of vessels, but on the digestion capacity of F.G.P. for fat. On the other hand, Elastase, a specific enzyme for lysis and synthesis of elastic components, prepared by Eisai Co., made a suppressive effect to the permeability of cerebral small vessels and facilitated markedly the digestion capacity of F.G.P. for fat, although the mechanism remained unsettled. From this standpoint, F.G.P. are also designated as "cerebral scavenger cells". PMID- 6924862 TI - The purification and partial characterization of human salivary kallikrein. AB - The major arginine esterase activity in human saliva has been purified. This enzyme lowers the blood pressure of a rabbit and produces kinins in acid treated dog plasma. It is therefore a kallikrein. The kallikrein has an unusual amino acid composition: aspartic acid and glutamic acid comprise 40% of the residues; the total number of basic residues is less than 5%; glycine and proline together make up more than 40% of the residues. The enzyme has a pI of 4.0 and an Mr of 27 000 as determined by dodecyl sulfate gel electrophoresis. On the other hand, sedimentation equilibrium data and the amino acid composition give an Mr value of only 9600. The enzyme could be a rather asymmetric molecule. The circular dichroism spectrum shows a minimum at 200 nm with [theta] = - 28 000 deg X cm2 X dmol-1. The spectrum suggests that the enzyme structure contains polyproline form II helix together with beta-turns. This structure is stable in the presence of dodecyl sulfate. PMID- 6924863 TI - Interaction of alkaloids with plant transfer ribonucleic acids. Effect of sparteine on lupin arginyl-tRNA formation. AB - The effect of the alkaloid sparteine on arginyl-tRNA formation was studied. It was demonstrated that sparteine sulfate in the concentration range 10-60 mM inhibits the charging reaction when amino acid, ATP and tRNA are used as variable substrates. The mode of action is different for all pattern of inhibition for all varied substrates is generally uncompetitive. A pattern of inhibition for all varied substrates is generally uncompetitive. A non-competitive mechanism for amino acid and tRNA was observed at low sparteine concentration, but in the case of ATP it is also uncompetitive. PMID- 6924861 TI - Protein synthesis by attached pulmonary macrophages. Effect of phagocytosis. AB - We studied the effect of phagocytosis of polystyrene latex beads on protein synthesis by pulmonary macrophages. To do this we determine the specific radioactivity of extracellular and intracellular free phenylalanine and of phenylalanine released from tRNA and used this information in calculating the rates of protein synthesis. Phagocytosis resulted in an increased rate of protein synthesis irrespective of which precursor specific radioactivity was used in the calculation. The rate of protein synthesis was increased per microgram polyribosomal RNA; but there was no increase in the amount of polyribosomal RNA in phagocytizing macrophages. The increase in the rate of protein synthesis (1.4 fold) was almost identical to the increase (1.3-fold) in the rate of ribosome transit in phagocytizing compared to nonphagocytizing macrophages. The decreased ribosome transit time during phagocytosis occurred without a fall in the average molecular weight of macrophage proteins. We conclude that phagocytosis increases the rate of protein synthesis in attached pulmonary macrophages and that this increased rate of synthesis can be accounted for almost completely by an increased rate of polypeptide chain elongation and/or termination. PMID- 6924866 TI - Quality of life. PMID- 6924865 TI - Quality of life in old age. PMID- 6924867 TI - Your mystery arrhythmia strips. PMID- 6924868 TI - Drug corner. Aprindine (Fibocil). PMID- 6924864 TI - Studies on serum complement and IgE in bronchial asthma. AB - Serum levels of the third component of complement (C3) were significantly lower in patients with perennial asthma and also in patients with the longer duration of the disease. No change in C3-proactivator (C3PA) and CH50 levels was observed in asthma patients. Significantly raised C4 levels were observed in the patients with late onset asthma. Raised serum IgE levels were found in all the three groups of asthma patients studied (depending on age of onset, duration and periodicity of the disease) above the control group. Within a group no difference was found with the duration or periodicity of the disease. However, low IgE levels were observed in patients with late onset asthma as compared to early onset asthma patients but this difference was not statistically significant. PMID- 6924871 TI - Performance appraisal of staff nurses - part III. Developing performance standards and an evaluation tool for staff nurses. PMID- 6924870 TI - Patient classification index documents staffing needs. PMID- 6924869 TI - Congestive heart failure. Part I: etiology, pathophysiology, and symptomatology. PMID- 6924872 TI - The legalities of critical care. Patient's rights. PMID- 6924873 TI - EKG of the month. (atrioventricular block). PMID- 6924876 TI - Calculating intravenous medications. PMID- 6924875 TI - Caring and sharing: neonatal nursing--use of a preemie needle. PMID- 6924874 TI - A guide to arrhythmia interpretation and management. Home study program. PMID- 6924877 TI - Nursing management in critical care units. Effective disciplinary action. PMID- 6924878 TI - Drug corner. Atenolol (Tenormin). PMID- 6924879 TI - Acute alcohol withdrawal syndrome in the critical care unit. PMID- 6924880 TI - Defibrillation. PMID- 6924881 TI - Disseminated intravascular coagulation. PMID- 6924882 TI - A nursing reference: gastrointestinal tubes and drains. Part I: intra-abdominal tubes and drains. PMID- 6924884 TI - Taking the anxiety out of hemodynamic monitoring: a skills lab. PMID- 6924883 TI - Congestive heart failure. Part II: medical and nursing management. PMID- 6924885 TI - Your mystery arrhythmia strips. PMID- 6924886 TI - Arrhythmia quiz. PMID- 6924887 TI - EKG of the month. PMID- 6924888 TI - The legalities of critical care. PMID- 6924889 TI - Problems in intracellular membrane traffic. AB - Eukaryotic cells operate an extensive and well regulated traffic of membrane bound vesicles to: (a) transport intracellularly, and eventually discharge by exocytosis, macromolecular products; (b) take up by endocytosis molecules and particles from the environment; (c) transport macromolecules across epithelial barriers; and (d) move membranes from their site of assembly to their final locations. Vesicular transport appears to be the equivalent of a discontinuous circulatory system in which vesicles recycle between the termini of each transport pathway, so that balanced membrane distribution is maintained among cell compartments and the cell's surface. Although the general outline of the process is reasonably clear, much remains to be learned about the number and types of pathways, the types and quantities of membranes, and the rates of vesicular movement. Since each vesicular carrier finds its specific terminus (and fuses with it), vesicular traffic is strictly controlled. By analogy with the control of intracellular protein traffic, it may be assumed that vesicular traffic is regulated by the mutual recognition of protein signals and receptors affixed, in this case, with appropriate asymmetry to the surface of the interacting membranes. Since vesicular transport operates without loss of specific chemistry and function of various cellular membranes, cells can counteract effectively the randomization of membrane proteins and lipids, which becomes possible whenever two membranes establish continuity of their fluid bilayers, and when membrane is removed from one or both termini of a recycling pathway. Specific selection of termini and prevention of randomization among membrane components are major unsolved problems in vesicular transport. Their solution in terms of molecular interactions requires further work. PMID- 6924890 TI - Membrane recycling. PMID- 6924892 TI - Biogenesis of epithelial cell plasma membranes. AB - Polarized monolayers of cultured epithelial cells, such as the kidney-derived MDCK cell line, when infected with enveloped viruses, provide a convenient model system for study of the intracellular routes followed by newly synthesized glycoproteins to reach specific domains of the plasma membrane. The polarized nature of the monolayers is reflected in the asymmetric assembly of enveloped viruses, some of which, such as influenza and simian virus 5 (SV5), bud from the apical surfaces of the cells, while others, such as vesicular stomatitis virus (VSV), emerge from the basolateral surfaces. MDCK cells can sustain double infection with viruses of different budding polarity, and within such cells the envelope glycoproteins of the two viruses are synthesized simultaneously and assembled into virions at different sites. Immunoelectron microscopic observations of doubly infected cells show that glycoproteins of influenza and VSV traverse the same Golgi apparatus. This indicates that critical sorting steps must take place during or after passage of the glycoproteins through the organelle. Following passage through the Golgi, the HA glycoprotein accumulates almost exclusively at the apical surface, where the influenza virions assemble. Significant amounts of the G protein, however, are detected on both plasma membranes in singly and doubly infected cells, although VSV virion assembly is limited to basolateral domains. These observations indicate that the site of VSV budding is not exclusively determined by the presence of G polypeptides on a given cell-surface domain. It is possible that other cellular or viral components are responsible for the selection of the appropriate budding domain or that the G protein found on the apical surface must be transferred to the basolateral domain before it becomes competent for assembly. PMID- 6924891 TI - Phagocytosis and fluid-phase pinocytosis. AB - The generation, flow, directionality and fusion of phagocytic and fluid-phase pinocytic vesicles in cultured macrophages and fibroblasts are reviewed. Specific plasma membrane (PM) receptors, receptor mobility, contractile cytoplasmic elements and lipid composition of the PM serve to regulate the flow of large phagosomes into the perinuclear zone. Fluid-phase vesicles are constitutively generated and carry large quantities of PM, fluid and solutes into the cytoplasm. Quantitative information is cited on the rates of vesicular generation, fusion with other members of the vacuolar system, fluid and solute uptake, and digestion and solute release. The nature and composition of fluid-phase vesicles, phagocytic vacuoles and PM are compared. Once interiorized, PM and its component polypeptides rapidly cycle back to the cell surface. The flow rates of both the centrifugal and the centripetal compartments as well as the fate of a minor degradation pool are illustrated and compared to the turnover of individual membrane polypeptides. Implications of membrane flow for cell shape, motility and new PM insertion are discussed. PMID- 6924893 TI - Structure of coated pits and vesicles. AB - Purified coated vesicles typically contain clathrin and auxiliary structural proteins of about 100 000 and 50 000 relative molecular mass (Mr). A model is described for the packing of clathrin trimers into the characteristic pentagons and hexagons of the surface lattices of coats. In a coated vesicle, clathrin appears to bind to an inner 'core' of particles containing the 100 000 and 50 000 Mr proteins. These core proteins may, in turn, bind to receptors in the membrane of the vesicle. The vesicle itself surrounds specific content molecules bound to their respective receptors. Budding coated vesicles are believed to act as molecular filters in cells. The known structural features of coated membranes are discussed in terms of this apparent role. PMID- 6924894 TI - Endocytosis, membrane recycling and Fc receptor function. AB - We have studied the composition and fate of plasma membrane internalized during both fluid-phase and receptor-mediated endocytosis in mouse macrophages. Particular attention has been paid to the macrophage Fc receptor, an intrinsic membrane glycoprotein that we have isolated and characterized biochemically and immunologically. Monoclonal and polyclonal antibodies directed against the receptor and against a series of other unrelated plasma membrane proteins have been used. In addition, we have used radioiodination techniques to label selectively the polypeptides of pinocytic vesicle membrane from within intact cells. Our results indicate that fluid pinocytosis in macrophages involves the internalization of a largely representative sample of plasma membrane polypeptides. Significantly, the Fc receptor seems to be internalized at a rate similar to that of most other membrane proteins. However, selective internalization of the receptor is induced during the endocytosis of certain ligands. The phagocytosis of immunoglobulin G (IgG)-coated erythrocyte ghosts results in the selective and largely irreversible removal of Fc receptors from the macrophage surface. Selectively internalized receptors do not recycle but are rapidly degraded. Fc receptors also appear to be preferentially interiorized during the rapid pinocytosis of IgG-containing soluble immune complexes. Uptake is accompanied by a sharp decrease in the number of surface receptors, which is partially reversed after the removal of ligand. PMID- 6924895 TI - Increase of fidelity of polypeptide synthesis by spermidine in eukaryotic cell free systems. AB - The mechanism of spermidine-induced increase of fidelity of polypeptide synthesis in a wheat germ cell-free system has been studied. It was found that the increase of fidelity in the presence of spermidine occurred mainly at the level of binding of aminoacyl-tRNA to ribosomes, that reduction of misreading was more marked at the 5'-base than at the 3'-base of the codon and that misreading caused by paromomycin and kanamycin C was not significantly decreased by spermidine. It was deduced from these results that spermidine inhibited low-frequency misreading more strongly than high-frequency misreading. In addition, spermidine was found to stimulate the rejection of non-cognate aminoacyl-tRNA mainly at an initial discrimination step during the binding of amino-acyl-tRNA to ribosomes, and slightly at a subsequent GTP-dependent discrimination step, the so-called proofreading step. In yeast, rabbit reticulocyte, and Artemia salina cell-free systems, spermidine was found to increase the fidelity of protein synthesis. PMID- 6924896 TI - A baboon model of bronchopulmonary dysplasia. II. Pathologic features. PMID- 6924898 TI - [Hardiness training of school children]. PMID- 6924899 TI - [Bronchitis in children]. PMID- 6924897 TI - Regulation of binding of initiator tRNA to eukaryotic initiation factor eIF-2. Effects of the haem-controlled repressor on the kinetics of ternary complex formation. AB - Ternary complex formation was studied in reticulocyte lysate supernatants and using rat liver eukaryotic initiation factor-2 (eIF-2) preparations. Haem deficiency reduced the rate of formation of ternary (Met-tRNAf . GTP . eIF-2) complexes by the eIF-2 in reticulocyte supernatants, the reduction being more marked when complex formation was assayed in the absence of GTP-regenerating capacity. Pretreatment with the haem-controlled repressor (HCR) reduced the rate of ternary complex formation by crude (liver) eIF-2. In contrast, complex formation by an almost homogeneous eIF-2 preparation was unaffected by HCR: sensitivity to HCR was however restored by a factor which catalyses exchange of guanine nucleotides bound to eIF-2. PMID- 6924900 TI - [Pregnancy that fails to develop]. PMID- 6924901 TI - [60th Anniversary of the formation of the USSR]. PMID- 6924902 TI - [Physioprophylaxis in obstetrics]. PMID- 6924906 TI - Establishing the social and economic value of nursing. PMID- 6924903 TI - [Pregnancy in the 34th-35th weeks. Glomerulonephritis]. PMID- 6924904 TI - [Acute leukemia]. PMID- 6924905 TI - [Differential diagnosis of gonorrhea]. PMID- 6924907 TI - "Four perspectives on physicians, nurses, power and games". PMID- 6924908 TI - [Diagnosis and treatment of uterine sarcoma]. AB - A group of 54 patients with uterine sarcomata is reviewed. The diagnosis, the pathological anatomy, the treatment and the prognosis of this rare disease which only comprises between 2-4% of all malignant tumours of the uterus is described. Special attention is directed to the tumours of so-called low grade malignancy, regarding their clinical and prognostic aspects in relationship to their morphology and biological potency. The discussion of the treatment centered around the desirability of additional chemotherapy. The answers to the numerous questions in this group of tumours can only be obtained by prospective collaborative studies of randomized groups of patients. PMID- 6924909 TI - [Conditions of metastatic spread of endometrial cancer: analysis of autopsy findings and clinical data]. AB - Among 263 patients who suffered from endometrial carcinoma and died of their disease or unrelated causes autopsies showed metastases or recurrences in 165 cases. The conditions for metastatic spread were analysed from the morphological parameters of the tumour. The incidence and localization of above all the lymph node metastases are closely correlated to the grading and the depth of invasion (I 0 to I 3/3) of the primary tumour. The incidence of pelvic lymph node metastases is 8.7% at an invasion depth I 1/3,33% at an invasion depth of I 3/3 of the myometrium. Tumours with the invasion depth I 1/3 show metastases in the para-aortic lymph nodes in 17.3% and at the invasion depth I 3/3 in 50% of the cases. At an invasion depth of I 3/3 17% had exclusively para-aortic lymph node metastases. Pelvic lymph node metastases were found in tumours of the grading G 1 in 5.7% of the cases, in grading G3 in 26% of the cases. The tumour grading and primary extent of the endometrial carcinoma area are closely correlated. At a grading G1 90% of the cases were in stage I/II and only 10% in stage III/or IV. At a grading G3 23.8% of the cases were stage I/II and 76.2% of the cases stage III/IV. Based on the presented analysis it is recommended to supplement the conventional treatment at an invasion depth I 2/3 of I 3/3 with radiotherapy of the para-aortic lymph nodes since 27.3 to 50% of these cases show para-aortic metastases. In 17% of the endometrial carcinomas with an invasion depth I 3/3 exclusively para-aortic lymph node metastases were found which do not respond to conventional treatment. PMID- 6924910 TI - [Bromocriptine and tamoxifen--a new therapeutic approach in suppression-resistant prolactin-secreting adenomas]. AB - In the present study the combination of tamoxifen and bromocriptine was tried for the suppression of prolactin in prolactin secreting adenomas which were resistant to suppression with bromoergocriptine alone. 10 women under treatment with 2.5-10 mg of parlodel (bromocriptine) for pituitary tumours of various sizes were additionally treated with tamoxifen 10-20 mg. (nolvadex) daily. Two patients had a previous incomplete resection for chromophobe adenomas. The other patients refused operation. Two women were also studied who did not tolerate a bromoergocriptine therapy because of side effects. In 6 of the 10 women with combination treatment a satisfactory suppression of the prolactin was observed. Four women were cleared of their amenorrhoea and galactorrhoea. One woman conceived. One woman lost her frigidity. Three women, among those the two with severe side effects from bromoergocriptine, tolerated the combined treatment well. Four women showed no success with the combined treatment. The effectiveness of the combined treatment was not correlated with the size of the tumour nor the clinical or biochemical baseline. The results lead to the conclusion that tamoxifen is capable of improving the suppression of prolactin or render the adenomas suppressible in a large number of cases. PMID- 6924911 TI - [The maternal perception of fetal movements during the last trimester of pregnancy]. AB - In a prospective study the foetal movements were simultaneously registered with two real time ultra-sound instruments and compared with the maternal perception of the movements. 35 patients were studied with a mean investigation time of 20 minutes per patient. The mothers pushed a button when they perceived a movements. Synchronous to this registration and storage on a tape were done of the movements of the upper and lower extremities the body movements and the foetal respiratory movements, the foetal heart rate and the uterine contractions. The mothers noticed a total of 38% of all foetal movements. Most frequently the mother noticed in 78% of the cases total foetal movements of the body and extremities. Isolated movements of the foetal body without movements of the extremities were only perceived by the mothers in 31% of the cases and isolated movements of the extremities were only perceived in 15%. In 69% of the cases the mothers correctly indicated that foetal movement took place. In 31% of all maternal signals there was no sonographic evidence of foetal movements of the body or the extremities. In 24% of these cases foetal respiratory movements were evident and in 23% of the cases Braxton-Hicks contractions were found. In 54% of these cases the signal button was used by the mothers without detectable reason. This high failure rate of maternal perception of foetal movements needs to be considered in the evaluation of foetal movements by the mother. PMID- 6924912 TI - [Incidence and causes of fetal and neonatal macrosomy]. AB - Amongst the 7486 babies born at the Department of Gynecology and Obstetrics in Cologne from 1974 to 1978, 536 neonates displayed a birthweight of more than 4000 g. The obstetrically relevant data from 523 deliveries were evaluated retrospectively. We compared and contrasted the results with a reference group of 511 neonates with a normal weight (2500-3999 g) according to the matched pair principle. The incidence of macrosomic neonates amounted to 7.2% of total deliveries in the observation period. On comparing the average age of the mothers, we found a rise from 27.4 years (mothers of the reference group) to 29.4 years in mothers of babies weighing 4000-4499 g and 30.3 years in mothers with babies weighing 4500 g and more. The proportion of the pregnant mothers over 40 years old was 4.6% as compared to 2% in the reference group in macrosomic babies. The parities show a decrease of the primiparae and an increase of the multiparae amongst mothers of macrosomic babies. The rate of primiparae was 49.3% in the group of babies of normal weight as compared to 33.3% in moderately overweight (4000-4499 g) and 23.4% in the highly overweight babies (4500 g and over). The large proportion of adipose mothers in neonatal macrosomy was also striking. The average weight of the women at the end of pregnancy was 71.4 kg in the reference group and rose to 78.6 or 86.8 kg, respectively, in the mothers of macrosomic neonates. In 453 puerperal mothers who had delivered a macrosomic baby, an oral glucose tolerance test (oGTT) was performed in the first 72 hours after delivery. This was pathological in 25.8% of mothers of moderately overweight children, and was pathological in 29.7% of mothers of distinctly overweight babies. This thus confirmed the correlation between diabetogenic metabolic stress and macrosomy. Evaluation of the course of birth revealed a distinctly raised risk of asphyxia with restriction of the vitality index and increase of abnormal internal and neurological features especially for the neonates with a weight of 4500 g and more. Our goal must therefore be to diagnose macrosomy better than so far by foetal biometry in order to counteract the risks described by prospective control of pregnancy and delivery. PMID- 6924913 TI - [Induction of cervix maturation by oxytocin vs. PGF2 alpha infusion, vs. intracervical PGE2 gel in risk cases with immature cervix]. AB - From April 1, 1978 to March 31, 1979 199 patients with a high risk pregnancy and a Bishop score of less than 7 among a total number of deliveries of 2075 needed induction of labour for medical indications. In 143 patients oxytocin infusions were given, in 56 patients PGF2 alpha infusions were given. It was shown that PGF2 alpha by infusion showed no advantages over oxytocin infusions. The duration of labour and delivery was not shortened. The foetal morbidity was not decreased. The incidence of Caesarean section remained unchanged at a high 32% and the incidence of vaginal operative delivery remained high at 50%. The incidence of post-partum acidosis in the newborn remained at around 14%. Therefore induction of labour was tried on the unripe cervix in the following 12 months with the intra-cervical application of 0.4 mg. PGE2 gel in 202 patients. The same criteria of high risk pregnancies and unripe cervices were used in the following 12 months. In contradistinction to the induction of labour with oxytocin infusion or PGF2 alpha infusion statistically very significant differences in favor of PGE2 gel were found. The foetal morbidity during labour, the duration of labour, the mode of delivery, the neonatal morbidity and the post-partum maternal condition regarding haemoglobin and pyrexia were improved. The low incidence of Caesarean section at 8% and the low incidence of post-partum acidosis in the newborn was especially noteworthy in the PGE2 gel group. Although excellence of prenatal care is essential for the improvement of obstetric results the timely termination of a high risk pregnancy is the second important step to reduce maternal and foetal morbidity. PGE2 gel intracervically improves this second step. PMID- 6924914 TI - [Diagnosis and treatment of intra-uterine contraceptive devices retained during pregnancy]. AB - 68 pregnancies were observed with an intrauterine device in place, and the threat no longer visible in the cervical canal. The various diagnostic and therapeutic possibilities are described. Ultra-sonography is capable of localizing the I.U.C.D. in 4/5 of the cases. In some cases a positive identification of the I.U.C.D. is only possible by radiographic methods. In order to reduce the maternal risk of infection and to increase the chances for an uncomplicated course of the pregnancy the intra-uterine device needs to be extracted even when the threat is no longer visible. The hysteroscopic localization and extraction was found to be the safest and most effective method of retrieval. Among 26 cases, removal was feasible in 25 cases, and 21 pregnancies remained undisturbed. PMID- 6924915 TI - [Depression and climacteric (psychometric studies on 116 women in a gynecologic polyclinic)]. AB - In 166 women who desired estrogen treatment for menopausal symptoms, psychosocial data were obtained prior to treatment, six weeks, three months and six months after treatment. The data were obtained by questionnaire and psychometric testing. 1. Of the 25% of women with significant depressive tendencies (according to EDS) 7 of 10 were also very anxious (according to EDS). 2. Emotional stability (according to MPI-N) present in every third woman without depressive mood changes but only in 3% of women with depressive changes. 3. Every third woman with depressive changes reported sexual fantasies or dreams. Only 3% of the women without depression had these fantasies. Discharge was complained of twice as often by depressive women (according to EPS) than in those without depression. 4. Pain on micturition was a complaint of half the women with depressive mood but only 1/8 of those without depression. 5. Heart palpitations were complained of by women without depression only half as often as by the other women. 6. The satisfaction with the role as women had a significant relationship to depression scores as expected. 7. The antidepressive and anxiolytic effect of estrogen treatment in the menopause was shown objectively by psychometric studies. The findings are discussed in view of a gynaecological office practice. PMID- 6924916 TI - Factor B polymorphism in North American blacks: study of a new variant Bf F1.35. AB - A "new" variant of the factor B (Bf) system has been found in the serum of three individuals of a North American Black family. This variant migrates faster than Bf F1 and has been designated Bf F1.35 on account of the relative electrophoretic mobility using reference Bf typed sera. This new factor B variant (F1.35) was found to be functionally active using a specific hemolytic overlay technique and was inherited on an HLA-A28;Bw35;C4 A3,B1;C2C;DR3;GLO2 haplotype. PMID- 6924918 TI - Subtyping of properdin factor B (Bf) by isoelectrofocusing. AB - Properdin factor B (Bf) is a polymorphic protein in the human plasma. Two common alleles, BfS, BfF, and two rare alleles, BfF1, BfS1, have been demonstrated in Caucasians. We now report that BfF can be subtyped into two alleles, BfFa and BfFb by isoelectrofocusing. Family studies indicate that they are inherited in a co-dominant pattern. Gene frequencies for Caucasians are: BfS 0.808, BfF1 0.019, BfS1 0.005, BfFa 0.038 and BfFb 0.128. PMID- 6924917 TI - Polymorphism of BF, C2, and GLO in Japanese patients with insulin-dependent diabetes mellitus: confirmation of an increase of BF*FT. PMID- 6924919 TI - Breakthrough to nursing. Breakthrough: its past...its future. PMID- 6924921 TI - Look it up! Building a reference library. Part II. PMID- 6924920 TI - Interdisciplinary education fosters integration/collaboration. PMID- 6924922 TI - Is your future in gerontological nursing? Wanted and needed: caring, committed, knowledgeable, skilled nurses. PMID- 6924923 TI - Tuning into nutritional education. PMID- 6924924 TI - Elderly abuse: a social quandary. PMID- 6924927 TI - You can write! PMID- 6924926 TI - Gerontological nursing a pleasant surprise. PMID- 6924925 TI - The rewards of gerontological nursing. PMID- 6924929 TI - ICN's programme on nursing in primary health care: present and future. PMID- 6924928 TI - Inhibition of zymosan-induced alternative complement pathway activation by concanavalin A. AB - Zymosan, a polysaccharide composed primarily of glucan and mannan residues, activates the complement system through the alternative complement pathway. We showed that zymosan-induced complement activation is inhibited by zymosan-bound lectins with carbohydrate specificities for mannosyl and glycosyl residues. Lectins unable to bind mannosyl or glucosyl residues did not inhibit zymosan induced complement activation. PMID- 6924930 TI - Basic nursing education for primary health care in the Caribbean. PMID- 6924931 TI - Nurses' participation in primary health care in Korea. PMID- 6924932 TI - The move towards primary health care in Spain. PMID- 6924933 TI - The fundamental influence of political, social and economic factors on health and health care. PMID- 6924934 TI - The private sector's contribution to primary health care in Lesotho. PMID- 6924935 TI - Teaching future nursing teachers primary health care. PMID- 6924937 TI - Identification of coagulase-negative staphylococci with the API staph system. AB - A kit for the identification of staphylococci based on the biochemical criteria proposed by Kloos and Schleifer (W.E. Kloos and K.H. Schleifer, J. Clin. Microbiol., 1:82-88, 1975) is now available commercially. The system was used to identify 100 strains of coagulase-negative staphylococci isolated from various body sites as the primary etiological agent of clinical infection. The increasing importance of staphylococci and their resistance to antibiotics provided the rationale for such an investigation. Over 90% of the Staphylococcus isolates were easily identified as to their species on the basis of their reaction profile to 19 biochemical tests included in the kit. The remainder, which showed minor variations, could also be assigned to the various species. Identification of the isolates was as follows: S. epidermidis, 54; S. haemolyticus, 5; S. simulans, 2; S. hominis, 1; S. capitis, 4; S. cohnii, 2; S. warneri, 2; S. xylosus, 8; and S. saprophyticus, 22. Antibiotic sensitivity patterns were determined for each of the isolates. Novobiocin resistance was detected in strains of S. saprophyticus and S. xylosus, a property hitherto recognized in Micrococcus sp. type 3 causing bacteriuria in young women. Resistance to penicillin was widespread among strains of several species, whereas resistance to tetracycline was mainly confined to strains of S. epidermidis. General resistance to sulfamethoxazole and nalidixic acid was found among all strains, with almost uniform sensitivity to the other drugs tested. PMID- 6924938 TI - Nurses' performance and interpretation of urine testing and capillary blood glucose monitoring measures. AB - This descriptive study attempts to identify the ways Registered Nurses (RNs) perform and interpret diabetic urine testing and capillary blood glucose monitoring measures. Seventy per cent of the RNs from one acute care hospital participated in the study. Seventy-six nurses participated; five of these comprising the pilot study. It was concluded that RNs did not perform these tests accurately according to standards. Knowledge of specimen collection procedures and drugs which affect urine testing results was not consistently high. RNs perceived the definitions of hypoglycaemia, normoglycaemia and hyperglycaemia more widely than standard ranges thus having major implications for patient care. RNs' experience with tests is not necessarily related to the accurate completion of the tests. Implications, limitations and idiosyncrasies of each test should be taught in addition to procedural specifics so that nurses can make sound judgements for patient care. PMID- 6924936 TI - Viral membrane proteins acquire galactose in trans Golgi cisternae during intracellular transport. AB - Frozen, thin sections of baby hamster kidney (BHK) cells were incubated with either concanavalin A (Con A) or Ricinus communis agglutinin I (RCA) to localize specific oligosaccharide moieties in endoplasmic reticulum (ER) and Golgi membranes. These lectins were then visualized using an anti-lectin antibody followed by protein A conjugated to colloidal gold. All Golgi cisternae and all ER membranes were uniformly labeled by Con A. In contrast, RCA gave a uniform labeling of only half to three-quarters of those cisternae on the trans side of the Golgi stack; one or two cis Golgi cisternae and all ER membranes were essentially unlabeled. This pattern of lectin labeling was not affected by infection of the cells with Semliki Forest virus (SFV). Infected cells transport only viral spike glycoproteins from their site of synthesis in the ER to the cell surface via the stacks of Golgi cisternae where many of the simple oligosaccharids on the spike proteins are converted to complex ones (Green, J., G. Griffiths, D. Louvard, P. Quinn, and G. Warren. 1981. J. Mol. Biol. 152:663 698). It is these complex oligosaccharides that were shown, by immunoblotting experiments, to be specifically recognized by RCA. Loss of spike proteins from Golgi cisternae after cycloheximide treatment (Green et al.) was accompanied by a 50% decrease in the level of RCA binding. Hence, about half of the RCA bound to Golgi membranes in thin sections was bound to spike proteins bearing complex oligosaccharides and these were restricted to the trans part of the Golgi stack. Our results strongly suggest that complex oligosaccharides are constructed in trans Golgi cisternae and that the overall movement of spike proteins is from the cis to the trans side of the Golgi stack. PMID- 6924940 TI - Spoken language and small groups: a student experience in graduate nursing education. PMID- 6924939 TI - Preparing the patient for a barium enema: a comparison of nurse and patient opinions. AB - The purpose of this research was to explore possible differences in nurse versus patient opinions about patient education information appropriate for the barium enema procedure. Twenty-eight nurses and 30 patients participated in the study. Findings showed that nurses believed a patient should have more information than the patients believed a patient needs, and that patients wanted only minimal detailed information about events that will happen during the procedure. Rather, patients were interested in knowing the benefits and purpose of the procedure while nurses believed that this information should be provided by the physician and not the nurse. Finally, nurses were dissatisfied, in general, about their patient education information that they have given to patients in the past for a barium enema procedure. PMID- 6924941 TI - A description of participant observation of clinical teaching. AB - As part of a study of clinical teaching in which I am currently engaged, it was necessary to try to discover what clinical teachers do, as opposed to what they say they do, or what other people think they ought to do. In order to obtain this information I arranged several periods of observation of a number of different clinical teachers. Prior to arranging these observations, which were carried out over a period of about 2 years, I carried out a literature search in order to discover what had been other people's experience in using this research method. In the following pages I have tried to describe the various types of observation that are commonly used, and to summarize the problems which have been discussed in the literature, illustrating and amplifying these points from my own experience. PMID- 6924943 TI - Academic espionage: dysfunctional aspects of the publish or perish ethic. AB - There are many dysfunctional manifestations relative to the tenure and promotion process. These are disruptive to academic life. Much of this is encouraged by the university because of their publish or perish ethic. Excellence in classroom teaching and success in the field of clinical and human endeavours are not highly valued in deliberations to grant tenure and advancement in academic rank. Research and publications are the major yardsticks upon which a faculty member is judged. This prevailing perspective poses a dilemma for many nursing faculty who have high clinical workloads and have not been socialized for academic survival. The pressures to publish and research can be achieved in a realistic and non stressful way. Three aspects seem to be particularly relevant to facilitate this achievement; these are: anticipatory planning, balancing the workload, and understanding the interpersonal dimensions of collegiality. PMID- 6924942 TI - Changes in patterns of care of the mentally handicapped: implications for nurses' perceptions of their roles and hospital decision making processes. AB - This paper reports on the findings of a longitudinal study of a mental subnormality hospital in the North of England. The focus is upon how nurses have experienced a major change in care and treatment of residents from 1978 to 1980. We explore, through the eyes of nurses, the change in their role from a predominantly nurturing/custodial one to a mainly educational/community orientated role. The research findings demonstrate that this change has increased nurses' self-esteem and their satisfaction with important areas of their work. There is some evidence also that nurses/resident relationships have improved in spite of reservations felt about new forms of treatment and community care. We suggest that such reservations may be linked to critical views expressed by nurses, particularly sisters and charge nurses, that decisions were taken about residents by other more senior personnel who had little contact with residents. One important conclusion of this study is that the traditional processes of decision making in the hospital appears to impede the full implementation of a major change which requires nurses to be involved in a potentially threatening process of altering their perceptions of themselves and residents. PMID- 6924944 TI - Work environments of different types of nursing subunits. AB - Based upon organizational theory, the purpose of this research was to identify and describe similarities and differences in the work environments of nine different types of nursing subunits (intensive care, medical, surgical, psychiatric, auxiliary, rehabilitation, rural, paediatric and obstetrical) in hospitals. Six measures of nursing subunit environment were developed: these included measures of nursing subunit autonomy, and the complexity and pervasiveness of other medical and hospital groups interacting with the nursing subunit. Data were collected by questionnaire from headnurses in 157 nursing subunits located in 24 hospitals in Alberta, Canada. The results indicated that the types of nursing subunits were similar in their degree of autonomy from both physicians and administration in the larger context in which they were located but were significantly different in terms of number and heterogeneity of groups outside nurses with which they interacted and the extent to which such groups pervaded the subunits. For example, intensive care units appeared as the type of nursing subunit with the greatest need for interaction with physicians, paramedics, hotel services and so on, whereas, psychiatric subunits appeared to be the least dependent on groups outside nursing in the hospital. These findings have implications for the management practices and educational programme for nursing. PMID- 6924946 TI - Promoting nursing research in the clinical setting. AB - The issues affecting the introduction of research values and activities to nurses in the practice setting are as much organizational and cultural as they are methodological and technical. The author shares her experiences in developing research knowledge and interest among clinical nurses, focusing on the problems she encountered and the means for addressing them. PMID- 6924945 TI - Guidelines for introducing change. AB - This article explores the various reasons that people resist change, introduces techniques for dealing with this resistance, and describes ways to adapt these techniques to individual situations. PMID- 6924948 TI - Training bicultural leaders. AB - Increasing numbers of hospitals now employ bicultural training programs to ease the school-to-work transition for new graduates. Nurses who conduct these programs must be specially trained to guide the new graduate in the process of becoming bicultural. Describing how one hospital sponsored a program that trained 24 nurses as bicultural leaders, the authors provide guidelines and insight to other potential sponsors. They offer specific information on planning, implementation (including direct and indirect costs), and evaluation. A follow-up article will focus on evaluation of the bicultural training program's effect on turnover and performance. PMID- 6924947 TI - The economics of health care and the future of nursing. AB - A national economist recognized for his work in health policy and human resources discusses the realities of economics as they affect some of nursing's most significant goals--education, reimbursement, and utilization. In presenting his outlook for health care and, specifically, nursing, Dr. Ginzberg sees obstacles to progress that are not impassable; he suggests that nursing leaders reassess their agenda and explore which goals can be achieved in the economic climate of the 1980s. PMID- 6924950 TI - Staff support groups: helping nurses to help themselves. AB - When the goals of staff development programming include increased introspection, problem-solving skills, or team effort, nursing administration may find that nurses are their own best resources. A nursing staff support group, run by a qualified leader, can offer nurses mutual help in reducing stress and managing conflict. PMID- 6924949 TI - "What do you mean I can't write?". AB - The ability to communicate in writing is a critical component of effective leadership. Yet, available "helpful hints" about business writing are often oversimplified, unspecific, or even misleading. This article, abridged from Harvard Business Review, identifies all the elements of business writing and provides a practical, commonsense discussion of each, to help you improve both upward and downward written communications in your organization. PMID- 6924951 TI - Clarifying autonomy and accountability in nursing service: part 2. AB - How can a nursing service convincingly argue for autonomy and accountability without an understanding of the precise meanings of these terms? In this second of two articles exploring the meanings and implications of autonomy and accountability in nursing service, Lewis and Batey arrive at this and other provocative questions. They analyze the concept of accountability and provide selected definitions of the concept by directors of nursing. Their discussion provides insights into the presence or absence of true accountability in nursing organizations and presents issues for further study. PMID- 6924952 TI - The 12-hour weekend plan--does the nursing staff really like it? AB - After nursing administrators at one Boston hospital implemented a new system for weekend coverage, they surveyed the staff's response to the trial plan. Here the author explains their system, what they learned when they measured its effects, and how they used staff responses to improve it. They proceed to examine the new system's effects on recruitment and absenteeism. The experiences shared here should assist other nursing administrators who are looking at new scheduling approaches and their viability in resolving staffing problems. PMID- 6924955 TI - Applying management information systems to staffing. AB - A management information system (MIS) is a tool for managing resources effectively. After reviewing some concepts and principles for effective data management, Hanson clearly applies the concepts to nurse staffing systems, which manage human resources. He defines a seven-step process for establishing an MIS, from defining the management objective to implementing the system. Pointing out that an MIS need not be computerized to be effective, Hanson presents a positive perspective and clarifies some often-misconceived notions about management information systems and the paper printouts they generate. In the next issue of JONA, a second article by Hanson will take a more detailed look at the variety, use, and usefulness of staffing statistics available from an MIS for staffing. These articles are based on material in a forthcoming book, Management Systems for Nursing Service Staffing, to be published by Aspen Systems Corporation, Rockville, Maryland. PMID- 6924956 TI - Skilled clinical knowledge: the value of perceptual awareness, part 1. AB - In this two-part article, the authors present strategies for clinical knowledge development, for documenting, conserving and enhancing the unique knowledge of the experienced clinician. In Part 1, they examine differences between practical and theoretical knowledge and discuss the implications for enhancing the practical knowledge nurses gain through clinical experience. Part 2, which will appear in the next issue of JONA, will examine clinical knowledge development as a means for enriching jobs, retaining experienced nurses, and improving patient care. PMID- 6924954 TI - Leadership in care of the elderly: assessing needs and challenges. AB - What opportunities and challenges for nursing leadership present themselves in institutions that provide care for our expanding aged population? Should nursing administrators take up these challenges? If so, what skills, resources, and attitudes will they need? This article opens the door for further exploration of these questions. The discussion stimulates thinking about the levels of involvement, authority, and responsibility that nursing administrators can and should have in providing care for the elderly. The article further suggests opportunities and benefits that such leadership can provide for patients, nurses, and society. PMID- 6924953 TI - Using registry nurses: coping with cost and quality issues. AB - If a nursing service uses agency nurses to help cope with staff shortages, the nursing administrator must manage the cost and quality of care delivered by these nurses. The authors describe their hospital's system for using agency nurses. The components of their system--an orientation program, contracts with the agencies, and systematic performance evaluation--can be used or adapted in other institutions. PMID- 6924957 TI - Decentralized budgeting: holding the purse strings, part 1. AB - A decentralized nursing structure allows the head nurse to become actively involved in the planning and budgeting process. In Nursing Decentralization: The El Camino Experience (published in November 1981 by Nursing Resources) the authors describe the development of a budgeting system that supports autonomy, accountability, and authority at the practitioner level. For JONA readers, we present, in two parts, an abridged version of the chapter "Budgeting: Holding the Purse Strings." Part 1, which follows, outlines important steps for the development of a successful and efficient budgeting program that can be adapted to meet the needs of other decentralized organizations. Part 2, which details a typical budget session, will appear in the next issue of JONA. PMID- 6924958 TI - Recruit from within: hospital nurse retention in the 1980s. AB - Nursing administrators and nurse recruiters coping with staffing shortages can profit from some recent studies of the causes of nursing turnover. Research reveals that the problem lies not in the motivations or characteristics of individual nurses but the nature of hospital nursing jobs and incentive structures. Using the research findings as a basis for discussion, Weisman suggests target areas for administrative intervention in the design of hospital nursing jobs. Her insightful commentary provides stimulus for some basic rethinking of the nature of nursing jobs and the traditional employer-employee relationship between hospitals and nurses--as well as some specific suggestions for "recruiting from within" to retain those productive nurses in whom the hospital has already invested time and money. PMID- 6924959 TI - What is leadership? PMID- 6924960 TI - Promoting research-based nursing: the nurse administrator's role. AB - As the practice of research increasingly becomes a part of the nursing profession, nurses must develop their ability to evaluate and incorporate the findings gained through the research process. This article reports the results of a survey aimed at determining problem areas existing among nursing staffs in understanding, accepting, and incorporating research findings. The report will help nursing administrators identify specific factors that inhibit the use of research findings and improve the conditions for incorporating research in their facilities. PMID- 6924961 TI - Rescue from neglect. LP/VNs help shape model practice act. PMID- 6924962 TI - Nursing duties. Your responses to JPN's fifth annual survey. PMID- 6924964 TI - NAPNES: new horizons in continuing education. PMID- 6924963 TI - Informed consent: the patient's right and the physician's duty. PMID- 6924967 TI - The use of social support in clinical practice. PMID- 6924966 TI - Designing psychiatric/mental health nursing for the future: problems and prospects. PMID- 6924969 TI - The unfinished task: development of nursing theory for psychiatric and mental health nursing practice. PMID- 6924968 TI - Consultation in community residences for the chronically mentally ill. PMID- 6924970 TI - [Specificity of serum elastase level in pancreatic diseases]. PMID- 6924971 TI - [Nursing of infants with asphyxia neonatorum. Keypoints in observation: analysis of cases observed at the Children's Center of Kanagawa Prefecture. Nursing during the acute stage]. PMID- 6924965 TI - Urinary germicides. PMID- 6924972 TI - [Nursing of infants with asphyxia neonatorum. Keypoints in observation: analysis of cases observed at the Children's Center of Kanagawa Prefecture. Nursing during the convalescent period]. PMID- 6924973 TI - [Nursing of infants with asphyxia neonatorum. Keypoints in nursing of infants with asphyxia neonatorum: from a physician's viewpoints]. PMID- 6924974 TI - [Practice of gyneco-obstetrics in the United States: a discussion]. PMID- 6924975 TI - [A trial at "delivery at home" at a house annexed to an obstetric hospital]. PMID- 6924976 TI - ["Home delivery", a new start for the family: an experience described by the father]. PMID- 6924977 TI - [Midwifery education - the way forward]. PMID- 6924978 TI - [Methodology in research surveys. 9. Various indices and their logical background. 1]. PMID- 6924979 TI - [The past and present of customs related to childbirth. 10. Admission of the infant into the society: outing rituals]. PMID- 6924980 TI - [Topics on physiological development of the fetus]. PMID- 6924981 TI - [Pregnancy and drugs. (4)]. PMID- 6924982 TI - ["Paternal identity" in man. When a man becomes a father]. PMID- 6924983 TI - ["Paternal identity" in man. Changing images of the father]. PMID- 6924985 TI - ["Paternal identity" in man. Significance of the Lamaze method. A discussion]. PMID- 6924984 TI - ["Paternal identity" in man. Effectiveness of a prenatal health education course with expectant fathers]. PMID- 6924986 TI - ["Paternal identity" in man. Danish families: the traditional family structures still preserved in the welfare society and related problems]. PMID- 6924988 TI - [Maternal and child health care planned by Kochi Medical University Hospital. The role of midwives at the hospital]. PMID- 6924987 TI - [Maternal and child health care planned by Kochi Medical University Hospital: management characteristics during delivery and the role of the hospital as a tertiary emergency center]. PMID- 6924989 TI - [Continuing midwifery education]. PMID- 6924991 TI - [Present and past customs related to childbirth. 11. Ceremonies celebrating the independence of the child: rituals related to dining and the 1st birthday]. PMID- 6924990 TI - [Survey of the interpersonal relationships in the homes of expectant mothers]. PMID- 6924992 TI - [Lessons on research surveys. 10. Various indices and their theoretical backgrounds. 2]. PMID- 6924993 TI - [Personal experience with delivery in Oakland, California]. PMID- 6924994 TI - [Charmed by the Lamaze method: experiences of practicing midwives]. PMID- 6924995 TI - [Intraperitoneal cystic patterns in the fetus]. PMID- 6924996 TI - [Women and obesity]. PMID- 6924998 TI - [Present and past customs related to childbirth. 12. The concept of the young life]. PMID- 6924997 TI - [Visit to Sakhalin: the social and medical conditions of the island]. PMID- 6925000 TI - [Pharmacological notes on midwifery. Pregnancy and medication. 6. Over-the counter drugs]. PMID- 6924999 TI - [Lessons on research surveys. 11. Various indices and their theoretical backgrounds. 3]. PMID- 6925001 TI - [Follow-up of infants exposed to phenobarbital in utero]. PMID- 6925002 TI - [Nutrition of expectant and puerperal patients and the interactions on the nursing scene. A discussion]. PMID- 6925003 TI - [Nutrition education given to patients by dieticians]. PMID- 6925005 TI - [Interactions with terminal patients without desire for recovery. Powerlessness of the nursing personnel]. PMID- 6925004 TI - [Nutritional care of pregnant and puerperal patients at Kitasato University Hospital: a case study]. PMID- 6925006 TI - [Interactions with terminal patients without desire for recovery. An experience with an aged patient with little hope for recovery]. PMID- 6925007 TI - [Interactions with patients without desire for recovery. Mental processes hidden in the "emptiness" of patients with chronic schizophrenia]. PMID- 6925008 TI - [Interactions with patients without desire for recovery. Interactions with patients having delusions]. PMID- 6925009 TI - [Interactions with patients without desire to live. Discussion: on psychological crises of patients]. PMID- 6925011 TI - [Bedside nursing. An experience with a patient who stayed alive for 122 days at the intensive care unit]. PMID- 6925012 TI - [Bedside nursing. Continued nursing of a diabetic patient based on a check list prepared by the hospital nursing staff]. PMID- 6925010 TI - [Activities of Yodogawa Christian Hospital in the past 10 years and its plan for the establishment of a hospice. Interview by Tawako Watarae]. PMID- 6925013 TI - [A clinical experience by a nursing student: application of the nursing process record]. PMID- 6925014 TI - [Ambulatory nursing conference. 8. At the Life Planning Center Clinic. Ambulatory care of a patient with a reduction in the diastolic pressure: preferred method of medical history taking]. PMID- 6925015 TI - [Clinical description of adolescence. 6. Psychopathology (1)]. PMID- 6925017 TI - [Questions and answers on oral (dental) diseases. 7. Jaw malformation and surgical treatment]. PMID- 6925016 TI - [Physiology and hygiene of smoking. 15. In vivo effects of passive smoking (2): on acute objective effects]. PMID- 6925018 TI - [Nursing application of transactional analysis. 17. Clinical application (1)]. PMID- 6925019 TI - [Profile of a nurse: Ms. Toku Inomata who is devoted to patients with muscular dystrophy]. PMID- 6925020 TI - [Aging report. Observation on geriatric care in England. 10. Visits to geriatric departments 6. Stourbridge and Dudley--recreation of a home-like atmosphere in facilities]. PMID- 6925021 TI - [Unforgettable life in Malawi. 10. Nursing education]. PMID- 6925023 TI - [Patient's complaints and a thought on the nursing approach]. PMID- 6925022 TI - [Patient's complaints and their interpretation--through interactions with a patient in delusions]. PMID- 6925025 TI - ["Problem" patients and those with few complaints]. PMID- 6925024 TI - [On communication with a patient with pulmonary tuberculosis who describes her symptoms in unique, variable ways]. PMID- 6925026 TI - [Factors obscuring patients' complaints--problems involving nursing]. PMID- 6925027 TI - [The diet as the starting point in building good health: creation of a "diet as the basis of life"]. PMID- 6925028 TI - [Mutsu General Hospital acting as a nuclear hospital in a remote area--innovation of regional health care by adopting the POS (problem-oriented system)]. PMID- 6925029 TI - [Ambulatory nursing conference. 9. At Life Planning Center Clinic. Communication with patients via telephone: conversations to solve patients' problems]. PMID- 6925030 TI - [Clinical aspects of adolescence. 7. Psychopathology. 2]. PMID- 6925031 TI - [Physiology and hygiene of smoking. 16. In vivo effects of passive smoking (3): chronic effects on children]. PMID- 6925033 TI - [Application of transactional analysis to nursing. 18. Examples of application 2]. PMID- 6925032 TI - [Questions and answers on oral diseases. 8. Abnormalities of the oral region: cleft palate and cleft lip]. PMID- 6925034 TI - [Aging report: observation on geriatric care in England. 11. Geriatric facilities in England. 7: Grantham, situated to the Northwest of London]. PMID- 6925035 TI - [Unforgettable life in Malawi. 11. African medicine and local customs]. PMID- 6925036 TI - [The image of the modern head nurse: truth and fiction in the projected image]. PMID- 6925037 TI - [Personal experience of a head nurse: encouragement through interactions with young nurses and patients]. PMID- 6925038 TI - [Personal experience of a head nurse. Drive and helping behavior: a reflection on the past 10 years]. PMID- 6925039 TI - [Personal experience of a head nurse. Awesomeness of the responsibility and the sense of helplessness]. PMID- 6925040 TI - [Personal experience of a head nurse. The importance of alertness in the human relationship]. PMID- 6925041 TI - [Personal experience of a head nurse. Daily activities of a head nurse: from the notes at the end of 1981]. PMID- 6925042 TI - [Expectations of a head nurse]. PMID- 6925044 TI - [Ambulatory nursing conference. 10. At the Life Planning Center Clinic. Sorting of patients' personal lives and guidance in daily activities]. PMID- 6925043 TI - [Regional rehabilitation activities organized at a local level. The current status and an overview of the regional rehabilitation activities in Nagasaki]. PMID- 6925045 TI - [Clinical aspects of adolescence. 8. Approaches in psychotherapy. (1)]. PMID- 6925048 TI - [Application of transactional analysis. 19. Examples of application (3)]. PMID- 6925046 TI - [Physiology and hygiene of smoking. 17. In vivo effects of passive smoking (4). Its relationship to lung cancer]. PMID- 6925047 TI - [Questions and answers on oral diseases. 9. Oral injuries]. PMID- 6925049 TI - [Profile of a nurse: Ms. Fujiko Iwasaki--in search of an active role of nursing in a private clinic]. PMID- 6925051 TI - [Unforgettable life in Malawi. 12. A parting thought]. PMID- 6925050 TI - [Aging report. Observation on geriatric care in England. 12. Various geriatric facilities in England. 8. St. Pancreas Hospital, London]. PMID- 6925052 TI - [The meaning of "nursing administration"]. PMID- 6925053 TI - [Research trends in the Nursing Administration Section of the Japan Nursing Academic Society]. PMID- 6925054 TI - [Objectices in the research on nursing administration. A discussion]. PMID- 6925056 TI - [On the discharge nursing summary. A conference]. PMID- 6925055 TI - [On the discharge nursing summary. Analysis of the records]. PMID- 6925057 TI - [Education for nursing administration: what investment yields highest returns?]. PMID- 6925058 TI - [An instrument for assessing and classifying patients by type of care]. PMID- 6925059 TI - [Preparation of a research plan. I]. PMID- 6925061 TI - [Lessons in the achievements of public health nurses in Hokkaido reclamation projects. Constant learning from the inhabitants]. PMID- 6925060 TI - [Lessons in the achievements of public health nurses in Hokkaido reclamation projects. Slow but steady progress in public health with the cooperation of the public]. PMID- 6925062 TI - [Lessons in the achievements of public health nurses in Hokkaido reclamation projects. Involvement with health problems closely related to daily life]. PMID- 6925063 TI - [Lessons in the achievements of public health nurses in Hokkaido reclamation projects. Revival of humanity in public health nursing]. PMID- 6925064 TI - [Lessons in the achievements of public health nurses in Hokkaido reclamation projects. Public health nurses' lives shared by the inhabitants]. PMID- 6925065 TI - [Faults of modern public health nursing. Closer interactions with the public. A discussion]. PMID- 6925067 TI - [Operation of a "language" class studied as a health guidance procedure following physical examinations]. PMID- 6925066 TI - [Regional public health nursing activities directed at the middle-aged and elderly segments of the population employed by small businesses]. PMID- 6925068 TI - [Physical examination and preventive health education for 40-year-olds at Itonuki cho, Gifu Prefecture]. PMID- 6925069 TI - [American nursing: the outline of development of nursing studies in the United States (II)]. PMID- 6925070 TI - [Patients' hope and nursing care]. PMID- 6925072 TI - [Support of the patient's desire to live]. PMID- 6925071 TI - [Current status of and an overview on continued nursing]. PMID- 6925073 TI - [Desire to live and a struggle to stay alive: an account by a patient]. PMID- 6925074 TI - [Psychological support of patients in the ICU]. PMID- 6925075 TI - [Patients' hope and nursing]. PMID- 6925076 TI - [Nursing in America in 1982 - opportunities, challenge, and conflicts]. PMID- 6925078 TI - [Role of the nurse in charge of infection control - monitoring, prevention, and control of hospital infections. Report on the International Conference on Infection Control held at Copenhagen from Nov. 6-10, 1978]. PMID- 6925077 TI - [Evaluation of the current nursing system]. PMID- 6925079 TI - [Happy mother and infants - a report by a nurse involved in obstetrical nursing]. PMID- 6925080 TI - [Profile of a nurse: Mrs. Noriko Shima who is actively engaged in solving sexual problems of inpatients]. PMID- 6925082 TI - [Medical topics: adrenal hyperplasia]. PMID- 6925083 TI - [Statistical files. Statistics on nursing schools and students compiled in April 1982]. PMID- 6925081 TI - [Medical topics: melatonin/cortisol ratio]. PMID- 6925084 TI - [Systematic nursing: a nursing process useful in clinical practice]. PMID- 6925086 TI - [Blood kallikrein-kinin system and microcirculation before and after different methods of surgical treatment of peptic ulcer]. PMID- 6925087 TI - [State of the kallikrein-kinin system of blood in patients with bronchial asthma]. PMID- 6925085 TI - Nursing in the Netherlands Antilles. PMID- 6925088 TI - Popular music and social values. PMID- 6925089 TI - Most cited authors and publications in health education journals for 1970-79. AB - This study attempted to answer the following questions about the journals Health Education, Health Education Monographs and the Journal of School Health. What authors have been cited the most in health education journals during the decade of the 70s? What authors have been cited the most in each health education journal? What articles and books have been the most cited in health education journals? What have been the most cited articles and books in each health education journal? It was found that the most cited author was L. W. Green, the most cited articles were L. W. Green "Toward Cost-Benefit Evaluations of Health Education: Some Concepts, Methods and Examples." Health Education Monographs and S. V. Kasl "Health Behavior, Illness Behavior and Sick-Role Behavior." Archives of Environmental Health and the most cited books was School Health Education Study, Health Education: A Conceptual Approach to Curriculum Design. Most cited authors, articles and books varied across the three journals. PMID- 6925090 TI - A comparison of sex education background between students from a private vs. a state university. PMID- 6925091 TI - Issues and problems related to the research on teenage fathers: a critical analysis. AB - Although there are few research studies on adolescent fatherhood, recently sufficient investigations have occurred to merit a critical analysis. In general, research in this area is marred by certain methodological deficiencies. Research in adolescent pregnancy generally ignores the fathers involved, and data on teenage fathers are often inferred or confounded by the use of biased report techniques. Retrospective and post hoc analyses often render inaccurate conclusions, and sampling methods generate unrepresentative subject pools. This article will demonstrate the ways these issues contaminate knowledge about teenage fathers. PMID- 6925092 TI - Assessing potential predisposition of elementary school children to heart disease. AB - Physical well-being has been designated a top priority for the children in the Clovis (California) Unified School District. In an effort to diminish coronary risk factors and encourage a healthy life style, a health assessment battery was developed for students in grades 1 through 6. The battery included measurements in height, weight, blood pressure, sit and reach flexibility, and skin-fold test for body fat composition. More than 5000 students were administered the tests by a health assessment team consisting of two nurses, three physical education resource teachers, and two clerical staff members. A random sample of 100 males and 100 females at each grade level was utilized for the statistical analysis. The correlation between body fat and weight was .80 (p v .05) in the fifth and sixth grades. Body fat was positively correlated with both systolic and diastolic measures of blood pressure. The coefficient averaged .21 (p v .05) over the 6 grades for systolic and .22 (p .05) over the 6 grades for diastolic blood pressure. Future plans call for the development of a longitudinal profile of students, as well as establishing district norms for the test battery. PMID- 6925093 TI - Teen advocate program. AB - The South Bay Free Clinic's Teen Advocate Program is comprised of three basic components: Clinic duties, outreach and CARE-line. The ten Teen Advocates (TA's) spend a total of ten hours per week divided among these activities. In the Clinic, they perform such duties as intake, blood pressure and hematocrit measurement, exam room assistance, birth control raps and answering the phones. Outreach consists mainly of speaking informally with their peers at school, home, parties or wherever young people congregate. Occasionally, TAs speak formally in high school classrooms or at youth-serving agency meetings (e.g. YWCA). They also distribute evaluation forms for each group presentation given. The CARE-line, a health information and referral helpline for teenagers, is staffed by Teen Advocates Monday-Thursday, 4-8 p.m. Adult volunteer supervisors provide necessary support and guidance for the teen listeners. PMID- 6925094 TI - Reduction of teenage pregnancy as a rationale for sex education: a position paper. AB - There is little doubt that the present level of interest in initiating sex education programs in the schools stems from the effort to reduce the teenage pregnancy rate. While one can hardly challenge the respectability of the goal to reduce teenage pregnancy, the writers take the view that the focus on reducing teenage pregnancy may be counter-productive to the establishment of effective sex education programs in school for the following reasons. 1. It promotes a narrow and incorrect understanding of human sexuality and sex education. 2. It creates misunderstanding of what constitutes a comprehensive sex education program. 3. Because the focus is on the junior/senior high youngster the assumption is left that sexuality occurs only between grades six and twelve. 4. It focuses primarily on the female and provides little education for the male. 5. It implies that the majority of teenagers want sex and not babies. 6. It implies that advocating sexual restraint is moralizing (and moralizing is bad) but teaching students that they should use contraceptives to avoid pregnancy is not moralizing. 7. The contraception approach presents human sexuality as a negative behavior because it conveys the impression that sex will get you into trouble if you do not know what to do. PMID- 6925095 TI - News from health research: toward a better understanding. AB - News about health research findings, especially regarding controversial topics, can seem confusing and conflicting to students and the general public. Many people eventually develop a "turned-off" attitude toward all health news. Yet medical information is one of the key factors involved in health decision-making, because it influences a person's judgment about the potential health impact of a behavior choice. As part of their health education, youngsters need to learn skills to better understand and evaluate reports of research news, so the information available for health decision-making will be more complete and accurate. Such news is already abundant in television, radio, newspaper and magazine reports and will continue to increase as research advances, knowledge expands and health "facts" are revised. This article outlines concepts and skills to help teachers and students understand the changes and controversies in health news. To most effectively use new information generated by medical research, students need to: 1) understand basic concepts about the nature of research and the research process; 2) apply critical thinking approaches to health news; and 3) locate additional health information resources. Generating ways to address these needs is a high priority of the school health education work at the National Heart, Lung and Blood Institute. Comments are invited on this approach. PMID- 6925096 TI - Self care: partnership for problem solving. PMID- 6925097 TI - Where should Health Science/Education be located administratively? PMID- 6925098 TI - Knowledge of upper respiratory tract infection in elementary school children. AB - Children often acquire health and disease information from their parents; and, as a rule, parents of a higher socioeconomic status are often better educated than those of lower socioeconomic status. This study assessed children's knowledge of upper respiratory tract infection and correlated the level of knowledge with socioeconomic status, ethnic background and frequency of school absences. Twenty two true-false questions were give to 331 elementary school children in grades two, four and six. Two schools were chosen because of differences in socioeconomic status of the prospective neighborhoods. The questionnaire was administered orally by one examiner while the children completed their own answer sheet. The higher socioeconomic status (SES) school had a correct mean score of 14.39, whereas the lower SES school had a mean score of 13.53. The mean correct score increased with grade level. White children had a mean correct score of 14.37, whereas non-white children had a mean correct score of 12.81. The mean correct score did not differ by sex. There was no correlation between mean correct score when compared to the students' claim of days missed from school because of upper respiratory infection. Students from both elementary schools appeared to have a general knowledge of etiology, symptoms, treatment and prevention of upper respiratory tract infection. PMID- 6925099 TI - Meal and snacking patterns of students. AB - A 1981 survey of 3,309 students in grades 3-12 enrolled in 135 Louisiana schools was used to determine their meal and snacking patterns. The data were analyzed according to three grade divisions: elementary, 3-6; junior high, 7-8; and senior high, 9-12. An analysis of variance was computed with grade division as the independent variable. Students' responses to questions concerning the consumption of meals, snacks and vitamin supplements, and tasting new, unfamiliar or disliked food were the dependent variables. A majority of students consumed three meals daily; however, breakfast was frequently skipped. Breakfast was usually eaten at home; 15% ate the school breakfast. Most students consumed the school lunch; many reported tasting new, unfamiliar or disliked food as part of these meals. Students snacked, most doing so in the afternoon. Students in grades 9-12 consumed significantly more snacks than their counterparts. Many snacks were purchased at school, primarily from a concession stand. Almost 50% took a vitamin supplement. PMID- 6925100 TI - The use of prescribed medication in the schools: a status report on the state policies and guidelines. AB - The increased use of medication in school systems and the broadened responsibility of educators for the medical/health related needs of students have created a number of concerns. Examples of issues facing school personnel include liability risks, designation of persons to administer medication and drug management procedures to safeguard students receiving drugs during the school day. A review of the literature indicates a paucity of legal documents and policies regarding the use of medication in schools. This study investigates existing state laws, regulations, attorneys general opinions and guidelines concerning the management of medication in the school system. The results show that: (a) the majority of states do not have legislation, regulations or other directives with force of law; (b) major policy statements found most often in legal documents were designated persons permitted to administer drugs, physician's approval, parent's authorization and liability; and (c) many states have apparently deferred policy making to the schools, and have developed state department guidelines to assist local school officials. The major policy and guideline statements may be considered as recommendations for adoption by states wanting to establish responsibility for policy making at the state and local school level. PMID- 6925103 TI - [Bedside examination: keypoints in nursing and interpretation of the data. Examination of the endocrine and metabolic systems (3): examination of patients with diabetes mellitus]. PMID- 6925102 TI - Life span development: intervention implications for concepts of aging. AB - The life span theory of development is based on the notion that development occurs at all ages. A person's developmental history influences his or her behavior later in life. Following this assumption, the ability of an elderly person to cope with health problems is related to past experience in coping with similar problems or life events. The goal of intervention related to life span development serves two purposes: to help individuals overlap positive health behaviors that will be sustained throughout life and to discuss the role and impact of life events on their ability to cope with later problems. The school health program provides an excellent vehicle for achieving these goals. PMID- 6925101 TI - Evaluation of an activity-centered health curriculum: assessment of cognitive knowledge. AB - This study was to determine how effective an activity-centered health curriculum was in providing health information to fourth, fifth and sixth-grade students in the Canton City school system. The assessment was facilitated by a posttest-only research design. Ten schools were randomly selected to receive a new health program, as compared to a control group of 10 schools which did not. Results indicated that the experimental students achieved significantly higher posttest cognitive knowledge mean scores than the control students. These findings were sustained for each grade level after adjusting for group differences in reading ability. PMID- 6925104 TI - [Study on changes in body temperature and pulse after bathing]. PMID- 6925105 TI - [Examination of temperature differentials in the normal and affected sides in hemiplegic patients - determination of the axillary temperature]. PMID- 6925107 TI - [Adverse effects of radiotherapy not associated with surgery for the treatment of cervical cancer - an observation on the acute symptoms and nursing actions]. PMID- 6925109 TI - [Total hysterectomy: methods and keypoints in postoperative care]. PMID- 6925110 TI - [Keypoints in pre- and postoperative nursing of patients undergoing total hysterectomy]. PMID- 6925108 TI - [Management of habitual constipation in children and adults with cerebral palsy]. PMID- 6925106 TI - [The role of the nursing personnel in emergency admission - a case of DIC caused by premature separation of the normal placenta]. PMID- 6925111 TI - [Nursing of a patient undergoing total hysterectomy: a case study]. PMID- 6925112 TI - [Assistance for a patient with cerebral infarction - an aged patient poorly motivated for rehabilitation]. PMID- 6925113 TI - ["Death", its meaning to the nursing personnel]. PMID- 6925115 TI - [Control of the parameters of the x-ray image intensifier]. PMID- 6925114 TI - [Modern x-ray intensifying screens]. PMID- 6925117 TI - [Choice of the physico-technical conditions for roentgenography with the RUM-20 apparatus]. PMID- 6925118 TI - [Operating characteristics of the RUM-20 apparatus in the roentgenography mode]. PMID- 6925116 TI - [Recording channels of the URI-230/150 x-ray image intensifier]. PMID- 6925119 TI - [Enzyme diagnosis of the complications occurring in radiation treatment of thoracic tumors]. PMID- 6925122 TI - [What the x-ray laboratory assistant must know to utilize RUM-20 x-ray diagnostic units]. PMID- 6925121 TI - [Operating characteristics of short-lived radionuclide generators]. PMID- 6925120 TI - [Operating characteristics of x-ray diagnostic units with x-ray image intensifiers]. PMID- 6925123 TI - [Characteristics of the photo processing of x-ray films]. PMID- 6925124 TI - [Duties of the head nurse]. PMID- 6925125 TI - [Nurse's work in an allergology office]. PMID- 6925127 TI - [Combining of jobs in the work of the paramedical personnel of a medical health unit]. PMID- 6925126 TI - [Use of pearl-pine baths in the ambulatory treatment of hypertension patients]. PMID- 6925128 TI - [Role of the nurse in performing contact radiation therapy with neutron sources]. PMID- 6925129 TI - [Deontology in the eye clinic]. PMID- 6925130 TI - [Patient preparation for x-ray study of the large intestine]. PMID- 6925131 TI - [In a united family]. PMID- 6925136 TI - [Phototherapy]. PMID- 6925135 TI - [Phonophoresis of drugs]. PMID- 6925139 TI - [Importance of "minor" psychotherapy at sanatorium and health resort institutions]. PMID- 6925132 TI - [Achievements of Soviet cardiology]. PMID- 6925133 TI - [Patient rehabilitation in varicose veins of the lower extremities]. PMID- 6925134 TI - [Physicopharmacological methods of preventing and treating diseases]. PMID- 6925140 TI - [Legend and truth about aid to developing countries]. PMID- 6925137 TI - [Visual field study]. PMID- 6925138 TI - [Work of the polyclinic in prophylactic examinations]. PMID- 6925141 TI - [Nurse and patient interrelationships]. PMID- 6925142 TI - Pharmacological abnormality of kallikrein-kinin system in hypertension. AB - Until recently the possible role of vasodilator systems in the etiology of hypertension has been largely ignored, although deficiency of vasodilator influence could be more important than the presence of vasoconstriction in determining vascular tone. Lower concentrations of urinary kallikrein excretion have been widely indicated in clinical and in several experimental hypertensive situations. The reduced plasma kininogen levels may reflect either decreased synthesis compensating for a chronically reduced kinin generation or genetic abnormality leading to reduced plasma kininogen, which may be a predisposing factor in hypertension. An alternative possibly could be enhanced adrenergic control during hypertensive conditions which may cause reduction in prostaglandin and kallikrein-kinin systems. It has also been suggested that most of the pharmacological actions of the kallikrein-kinin system are mediated through prostaglandin formation. Thus, subnormal kallikrein-kininogen-kinin concentrations could be the cause of reduced vasodilating influence leading to both clinical and experimental hypertension. PMID- 6925143 TI - Theoretical mechanisms for synthesis of carcinogen-induced embryonic proteins: XI. A theoretical interpretation of the sequential methylation of yeast phenylalanine tRNA. AB - Theoretical studies on the mechanisms of methylation of tRNA was reported in a previous paper dealing with the induction of genic activity of proposed "embryonic" tRNA methylases. The mechanism described only the first methylation of a tRNA that had a known structure, namely yeast phenylalanine tRNA. In this paper, a complete scheme of methylation for the molecule is reported in detail using molecular model building. The mechanism uses only one specific uridine residue with which S-adenosyl-L-methionine complexes for all required methylation sites. PMID- 6925144 TI - Putting MRSA into perspective. PMID- 6925145 TI - Antibiotic-resistant staphylococci in a teaching hospital. AB - A large, continuing outbreak of infection and colonisation with a Staphylococcus aureus which is resistant to methicillin and gentamicin is reported. Affected patients and staff members seen between September, 1980, and August, 1981, are reviewed in detail. Methods of management of such persons and their treatment, if required, are discussed. The antibiotic-resistant Staph. aureus is readily disseminated in hospitals and may cause outbreaks of infection in wards, which require isolation of affected patients in the attempt to control the problem. It is suggested that a special isolation unit is needed. Use of the few effective antibiotic agents should be restricted. Despite these measures, the spread of this organism may not be contained. PMID- 6925146 TI - ESRD treatment modalities: the patient does have the right to choose. PMID- 6925147 TI - A clinical career pathway: the Mount Sinai experience, Part I. PMID- 6925148 TI - Quality in graduate nursing education. PMID- 6925149 TI - Primary nursing: two faces with little acquaintance. PMID- 6925150 TI - First aid for choking: a successful community education program. PMID- 6925151 TI - Toward a theory of gerontological nursing. PMID- 6925152 TI - Sudden pediatric death: meeting the needs of family and staff. PMID- 6925154 TI - Fostering professional nursing careers in hospitals: the role of staff development, Part 1. PMID- 6925153 TI - Using peer groups in nursing education. PMID- 6925156 TI - Assertiveness education: one method for teaching staff and patients. PMID- 6925155 TI - Curriculum building: process and products. PMID- 6925157 TI - Ingredients for successful networking. PMID- 6925158 TI - Curriculum revision: evaluation of prerequisite courses in a baccalaureate nursing program. PMID- 6925159 TI - Critical elements of diabetes education in the workplace. PMID- 6925160 TI - Job stress: its impact in the diabetic worker. PMID- 6925161 TI - Obesity and diabetes: their relationship and treatment. PMID- 6925162 TI - Assessment and treatment of diabetes emergencies in the work setting. PMID- 6925163 TI - Resources in diabetes for the occupational health nurse. PMID- 6925164 TI - Diabetes mellitus. New approaches to an old disease. PMID- 6925165 TI - Nurse Smith's notes: understanding drug treatment. 4. Antibiotics. 1. PMID- 6925166 TI - Aspects of teaching. PMID- 6925167 TI - Aspects of teaching: a springboard to the future. PMID- 6925168 TI - Aspects of teaching: let the computer do the work. PMID- 6925169 TI - Facilitators--a personal view. PMID- 6925170 TI - Nursing and journalism--legal and ethical considerations. PMID- 6925171 TI - Aspects of teaching: two into one won't go. PMID- 6925172 TI - Nurses on the dole. PMID- 6925173 TI - Nurses on the dole: job loss and job change. PMID- 6925175 TI - Israeli diary 1. PMID- 6925174 TI - Nursing care study: a correct compassion. PMID- 6925176 TI - Functional bracing--1. Functional bracing of Bennett's fracture. PMID- 6925178 TI - A travelling day hospital. PMID- 6925177 TI - Functional bracing--2. Functional bracing of humeral fractures. PMID- 6925180 TI - Satisfying and anxiety-creating incidents for nursing students. PMID- 6925181 TI - Are midwives 'with' mothers? PMID- 6925179 TI - Systems of life No 96. Systems and signs: locomotor systems - 2. Upper limb. PMID- 6925182 TI - Planning for old people. PMID- 6925183 TI - A race apart: caught between cultures. PMID- 6925184 TI - A race apart: nursing the Aborigines. PMID- 6925185 TI - Functional bracing--3. Functional bracing of metacarpal fractures. PMID- 6925187 TI - Stuck in a job ... and getting unstuck. PMID- 6925186 TI - Functional bracing--4. The treatment of forearm fractures. PMID- 6925188 TI - Israeli diary 2. PMID- 6925189 TI - The hospital that opened its doors. PMID- 6925190 TI - How many health visitors? PMID- 6925191 TI - Nurse management courses: a way to improved practice. PMID- 6925193 TI - Spotlight on children: the changing face of inner city paediatrics. 3. A children's casualty department. PMID- 6925192 TI - Spotlight on children: the changing face of inner city paediatrics. 1. Gastroenteritis. PMID- 6925194 TI - Spotlight on children: the changing face of inner city paediatrics. 4. The assessment centre. PMID- 6925195 TI - Spotlight on children: the changing face of inner city paediatrics. 5. A student nurse's view. PMID- 6925196 TI - A balancing Act. Interview by Andres Cole. PMID- 6925199 TI - Skin care during radiotherapy. PMID- 6925197 TI - Managing the cost of nursing. PMID- 6925198 TI - One nurse's war: a duty to care. Interview by Jamie Fleming. PMID- 6925200 TI - Breakdown: commonsense psychiatry for nurses. 2. The schizophrenias. PMID- 6925201 TI - Functional bracing--5. The development of a functional brace for the treatment of mallet fingers. PMID- 6925202 TI - Functional bracing--6. A biomechanical approach to the treatment of phalangeal fractures. PMID- 6925203 TI - Discussion groups for mothers--1. PMID- 6925205 TI - Nurse Smith's notes: understanding drug treatment. 5. Antibiotics 2. PMID- 6925204 TI - The need for family planning in psychiatric hospitals. PMID- 6925206 TI - Ward sisters: their problems at work--1. PMID- 6925207 TI - Pay review body - golden chance or con-trick? PMID- 6925208 TI - Practical dreamer. Interview by Laurence Dopson. PMID- 6925210 TI - The health visitor's dilemma: discussion groups for mothers - 2. PMID- 6925212 TI - Functional bracing--7. Functional bracing of fractures of the tibia and fibula. PMID- 6925211 TI - Vitrectomy surgery. PMID- 6925209 TI - Attitudes to death and bereavement among cultural minority groups. PMID- 6925213 TI - Functional bracing--8. Functional bracing of femoral shaft fractures. PMID- 6925214 TI - Ward sisters: their problems at work-2. PMID- 6925215 TI - Too much Christmas spirit? PMID- 6925216 TI - A home from home. PMID- 6925217 TI - Crisis at Christmas. PMID- 6925219 TI - A holiday with a difference. PMID- 6925218 TI - The show must go on. PMID- 6925220 TI - Out of the ordinary. PMID- 6925221 TI - Nursing care study: coping with terminal cancer. PMID- 6925222 TI - Functional bracing--9. Bridge engineering at its most intricate. PMID- 6925223 TI - Cryoanalgesia following thoracotomy. PMID- 6925224 TI - Improving communication skills. PMID- 6925225 TI - District nurse training. 1. Organising research. PMID- 6925226 TI - District nurse training. 2. Difficult changes. PMID- 6925227 TI - Looking back. PMID- 6925228 TI - From home to home. PMID- 6925229 TI - Antenatal clinics. 3. Make it worth the wait. PMID- 6925232 TI - The art of observation. 16. Perchance to dream. PMID- 6925230 TI - Hand injuries. PMID- 6925231 TI - Nurse practitioners: taking over the pressure. PMID- 6925233 TI - It's child's play. PMID- 6925234 TI - Cancer: now is the time for optimism. PMID- 6925236 TI - Survival kit for managers. 10. Implementing clinical research findings. PMID- 6925235 TI - Law. 2. Framework for learning. PMID- 6925237 TI - Twins: double trouble. PMID- 6925238 TI - Nursing care study: back on her feet again. PMID- 6925239 TI - Never mind the hygiene, what about the politics? PMID- 6925240 TI - Education: teaching the patient. PMID- 6925243 TI - Mental illness: out and about. PMID- 6925242 TI - Issues in Nursing Conference: focus on the community. PMID- 6925241 TI - Discipline: I don't like your attitude nurse! PMID- 6925244 TI - Careers: control of infection. PMID- 6925248 TI - Carcinoma of the tongue. PMID- 6925247 TI - Radio phone-in: 'I just want to talk to someone.'. PMID- 6925245 TI - A friend in need. PMID- 6925246 TI - Art of observation, 17. A painful lesson. PMID- 6925249 TI - A family affair. Travel scholarship. PMID- 6925250 TI - A job under scrutiny. Travel scholarship. PMID- 6925251 TI - Law. 3. A student and an employee. PMID- 6925252 TI - Antenatal clinics. 4. More than a laying on of hands. PMID- 6925254 TI - Survival kit for managers. 11. Monitoring the services. PMID- 6925255 TI - Community nursing. 2. Teaching to a plan. PMID- 6925253 TI - Psychiatry: shock treatment. PMID- 6925256 TI - Ethics: is there a skill in human relationships? PMID- 6925257 TI - A legacy of tradition. PMID- 6925258 TI - Careers: mental handicap nursing. PMID- 6925259 TI - [Rhythm of drug administration]. PMID- 6925260 TI - [Oxytocia]. PMID- 6925261 TI - [Progress in nephrology]. PMID- 6925264 TI - [Alcoholic intoxication]. PMID- 6925262 TI - [Is it really an advance?]. PMID- 6925263 TI - [Let us improve basic medical care]. PMID- 6925265 TI - [Adaptaton once again]. PMID- 6925266 TI - [Patient cognition]. PMID- 6925268 TI - [Without capital investment but to good result...]. PMID- 6925269 TI - [Higher and higher qualifications]. PMID- 6925267 TI - [Disorders of the course of labor]. PMID- 6925270 TI - [In the withdrawal ward]. PMID- 6925272 TI - [Home care]. PMID- 6925271 TI - [Rhythm of health. Clinical problems]. PMID- 6925273 TI - [Nurses in the community]. PMID- 6925276 TI - [Remarks on correspondence studies]. PMID- 6925274 TI - [Class drills in the work room]. PMID- 6925275 TI - [Bronchological diagnosis of lung diseases]. PMID- 6925278 TI - [How to eat economically and healthly]. PMID- 6925277 TI - [Professional ceremonies]. PMID- 6925279 TI - [Profession or vocation]. PMID- 6925280 TI - [Determinants of drug resistance in bacteria]. PMID- 6925281 TI - [Trichomoniasis]. PMID- 6925282 TI - [Specialized training of midwives]. PMID- 6925283 TI - [Examination--but what kind?]. PMID- 6925284 TI - Pediatrics: nursing assessment & judgment. PMID- 6925286 TI - Legal case briefs for nurses. CT: abdominal surgery: needle count policy; TS: Obs: delay in treatment fatal to patient. PMID- 6925285 TI - License revocation and suspension: R.N. rights. Case in point: Conlon v. Commonwealth State Board of Nurse Examiners (449 A. 2d 108 - PA). PMID- 6925287 TI - R.N. supervisors: enforcing hospital policy. Case in point: Cooper v. State (453 N.Y.S. 2d 483 - NY). PMID- 6925288 TI - [Attempted interpretation of water injected into the inguinal artery on the augmentation of intramammary pressure of the sheep]. AB - The increase in intramammary pressure caused by injecting small amounts of water into the udder artery of anesthetized ewes does not seem to be a nervous reaction induced by the stimulation of sensitive mammary receptors: the deflections remain unchanged after complete denervation of the gland (fig. 4) and after the injection of water at different temperatures (4 to 37 degrees C; fig. 1) or pH's (4.6 to 9.8; fig. 2). Since injecting the same volumes of blood (fig. 3), isotonic NaCl (fig. 5) or glucose (fig. 6) solutions does not cause the intramammary pressure to increase, water effect would appear to result from a change in blood osmotic pressure. Among the substances released when the blood corpuscles or platelets are destroyed, kallikrein and histamine do not seem to play a role. These products induce intramammary pressure to rise (fig. 7, 9) but latency and duration are longer than with water Also, their respective inhibitors, aprotinin and phenergan, always block their effect on intramammary pressure but not that of water. On the other hand, water and bradykinin (fig. 8) produce similar responses, indicating that the latter substance may play a role. We must consider also the possible action of extra-capillary water transfer, modifying ion flux and myoepithelial cell membrane potential or simply inducing the alveolar cells to swell and the acini to flatten. This last hypothesis permits a better interpretation of the pressure decreases noted after injection of hypertonic solutions (figs. 5, 6) since reverse water movements would have the opposite effect. PMID- 6925289 TI - [24-hour urinary kallikrein excretion profile in the normal human]. PMID- 6925290 TI - [Sterilization control: the new and the old]. PMID- 6925292 TI - [Health care users, what do we want? From the National Federation of Health Care User Groups]. PMID- 6925291 TI - [Occupational health nursing: coming out of isolation. Interview by J Bregetzer]. PMID- 6925294 TI - [The department of Health and nurses education]. PMID- 6925295 TI - [Being well, for a patient with cancer, is it possible?]. PMID- 6925293 TI - [15 Eugene Millon street]. PMID- 6925296 TI - [Prostaglandins: hopes and realities]. PMID- 6925297 TI - [Health questionnaires in daily medicine]. PMID- 6925299 TI - [Social security 3: general health insurance regimen: payments]. PMID- 6925298 TI - [Therapy: anti-Parkinson medication]. PMID- 6925300 TI - [Eruption disorders of the lower wisdom teeth]. PMID- 6925302 TI - [One hand washes the other]. PMID- 6925301 TI - [Sports health, on tip-toes]. PMID- 6925303 TI - [Old age: our future]. PMID- 6925304 TI - [The 4th Nursing Conference: for those who didn't attend]. PMID- 6925305 TI - [Nursing care and community health at the Red Cross]. PMID- 6925306 TI - [The abused child: institutional violence]. PMID- 6925308 TI - [Deafness]. PMID- 6925307 TI - [Hospital rooms]. PMID- 6925310 TI - [Cutaneous ureterostomy]. PMID- 6925309 TI - [Hearing aids for the hearing impaired]. PMID- 6925312 TI - [Ankylosing spondylitis]. PMID- 6925311 TI - [Migraine]. PMID- 6925313 TI - [Obstructive myocardiopathy]. PMID- 6925314 TI - [Grippe: clinical forms, complications, treatment]. PMID- 6925316 TI - [Influenza and acute respiratory syndromes. A frequent pathology to be studied better]. PMID- 6925315 TI - [Prevention of grippe. Principles of vaccine manufacture]. PMID- 6925317 TI - [Anti-grippe vaccination]. PMID- 6925318 TI - [Epidemiology of the flu]. PMID- 6925319 TI - [Chlamydia respiratory infections]. PMID- 6925321 TI - [A case of mycoplasma pneumopathy]. PMID- 6925322 TI - [Survey on the application of psycho-administrative education in a para-medical environment]. PMID- 6925324 TI - [Allergy tests in the asthmatic]. PMID- 6925323 TI - [The role of grippe in acute respiratory disease]. PMID- 6925325 TI - [Asthma. Attempting to render the disease less invalidating]. PMID- 6925320 TI - [Methods of rapid diagnosis in virology (apropos of influenza and acute respiratory syndrome)]. PMID- 6925329 TI - [Psychology of the asthmatic]. PMID- 6925327 TI - [Physiopathologic bases of asthma]. PMID- 6925328 TI - [Therapeutic measures in asthmatic disease]. PMID- 6925331 TI - [Asthma and surgery]. PMID- 6925326 TI - [Report of a case: status asthmaticus]. PMID- 6925330 TI - [Life hygiene of the asthmatic]. PMID- 6925332 TI - [Preoccupations of the ANFIIDE (National Association of State Diploma Nurse) on the eve of the Congress at Caen. Interview by E. Rogez]. PMID- 6925333 TI - [Functional respiratory tests in asthmatic disease]. PMID- 6925334 TI - [Atopic dermatitis]. PMID- 6925335 TI - [Contact eczema]. PMID- 6925336 TI - [Dermatology of a few common disorders]. PMID- 6925339 TI - [Mycoses]. PMID- 6925338 TI - [Local anti-infective treatment in dermatology]. PMID- 6925337 TI - [Treatment (simple and effective) of leg ulcers]. PMID- 6925340 TI - [Local corticoids]. PMID- 6925341 TI - [Liberal exercise of the profession]. PMID- 6925342 TI - [Health Day. "Health education experiences should be made universal"]. PMID- 6925343 TI - [Lice and scabies]. PMID- 6925344 TI - [Value of psychoanalysis and role of psychotherapy in autism and early psychoses]. PMID- 6925345 TI - [Autism and early childhood psychoses. Need for early diagnosis and management]. PMID- 6925346 TI - [General principles determining the management of treatment of the child and assistance to the family in early psychoses]. PMID- 6925348 TI - [Multidisciplinary approach to autism and early childhood psychoses. (National Conference of the Child and Adolescent Psychiatry Society of France, Reims, 15 May 1982]. PMID- 6925349 TI - [I work with psychotic children]. PMID- 6925350 TI - [Diagnosis of depressive states and their ambulatory treatment]. PMID- 6925352 TI - [Admission of the patient at the emergency department by the nurse and the surgeon: fractures of the ankle]. PMID- 6925351 TI - [The social nurse of a human genetic center confronted with familial mental retardation]. PMID- 6925347 TI - [Meeting with a psychotic child: mediation of the bath]. PMID- 6925353 TI - [Preparation of the operating room and the cast room for an ankle fracture]. PMID- 6925354 TI - [Anesthesia in ankle fractures]. PMID- 6925355 TI - [Treatment of bimalleolar fractures]. PMID- 6925358 TI - [Study of the physical environment at the workplace. Lighting in an operating room and at a nurses' station]. PMID- 6925356 TI - [Review of the anatomy and physiology of the ankle joint]. PMID- 6925357 TI - [Bimalleolar fractures. Care after treatment. Secondary complications]. PMID- 6925359 TI - [Resection of the small intestine, monitoring, treatment and diet]. PMID- 6925360 TI - [Anatomopathology of bimalleolar fractures. Different types of fractures]. PMID- 6925361 TI - [Late complications of bimalleolar fractures]. PMID- 6925362 TI - [Fractures of the astragalus. Anatomic and physiologic review. Different types of fractures. Initial examination of the patient]. PMID- 6925363 TI - [Ankle fractures. Importance of rehabilitation, prevention of complications]. PMID- 6925366 TI - [Rehabilitation of bimalleollar fractures]. PMID- 6925364 TI - [Fractures of the astragalus. Treatment, post-therapeutic monitoring, late complications]. PMID- 6925365 TI - [Case report: the bimalleolar fracture of Madame B...]. PMID- 6925367 TI - [Fat emboli]. PMID- 6925368 TI - [Social problems--reinsertion]. PMID- 6925369 TI - [Value of upper digestive system endoscopy in preliminary investigations in tropical practice]. PMID- 6925370 TI - [Upper digestive pathology. Particular problems for a non specific pathology]. PMID- 6925371 TI - [Enteral parasitoses: association of therapy to action on socioeconomic factors]. PMID- 6925374 TI - Pertussis vaccine controversy. PMID- 6925373 TI - [Dyspepsia]. PMID- 6925375 TI - Some observations on nursing and health care in China. PMID- 6925372 TI - [Role of the supervisory nurse in a medical department in Black Africa]. PMID- 6925376 TI - Journal - a one day report - professional experience in China. PMID- 6925377 TI - [Torsion of the testicle and of its' appendages]. PMID- 6925379 TI - [Position on current pathology of the vagino-peritoneal canal and the external genital organs in children]. PMID- 6925378 TI - [Phimosis]. PMID- 6925380 TI - [Hypospadias]. PMID- 6925382 TI - [Anatomy and embryology of the inguinal canal in children]. PMID- 6925381 TI - [Surgical treatment of hypospadias: the role of the nurse]. PMID- 6925383 TI - [Abnormalities and malformations of the genital organs in girls]. PMID- 6925384 TI - [Treatment of pulmonary tuberculosis during pregnancy: the extensive practice of pulmonary radiography is justified]. PMID- 6925385 TI - [Estrogens and vascular thrombosis]. PMID- 6925386 TI - [Pregnancy and environment. Monitoring and outcome of pregnancy of women followed in non-hospital maternal-child welfare centers]. PMID- 6925388 TI - [Inguinal hernia, hydrocele, cord cyst]. PMID- 6925387 TI - [Utrogestan]. PMID- 6925389 TI - [Fetal hypotrophy: definition, etiology]. PMID- 6925390 TI - [Long term prognosis of hypotrophic newborn infants]. PMID- 6925392 TI - [Care of hypotrophic newborn infants]. PMID- 6925393 TI - [The hypotrophic newborn infant: initial care, monitoring in the first days of life, psycho-affective environment, future]. PMID- 6925391 TI - [Above all monitoring pregnancy and adequate prenatal care]. PMID- 6925394 TI - [Clinical diagnosis and supervision of the pregnancy in cases of fetal hypotrophy]. PMID- 6925396 TI - [Amenorrhea]. PMID- 6925397 TI - [Duphaston]. PMID- 6925395 TI - [A few ideas to remember on fetal hypotrophy or intrauterine growth retardation]. PMID- 6925398 TI - [Towards improving the integration of the child in the child care center]. PMID- 6925399 TI - [Value of echotomography in the diagnosis and monitoring of fetal hypotrophy]. PMID- 6925401 TI - The new tax changes. PMID- 6925400 TI - [Experimental basis for the participation of the kallikrein-kinin system in the mechanisms of normal and pathological hemostasis regulation]. PMID- 6925402 TI - Statistics and competencies: associate degree nursing. PMID- 6925404 TI - [Fear of roentgen rays justified?]. PMID- 6925403 TI - Differences in prekallikrein and high molecular weight kininogen levels in two strains of Brown Norway rat (Kitasato strain and Katholiek strain). PMID- 6925406 TI - [Professionalization, new style]. PMID- 6925405 TI - [Sages and mental gurus]. PMID- 6925407 TI - [Nursing ethics and nursing education. I. Observations concerning the first international congress on nursing law and ethics]. PMID- 6925408 TI - [The need for cost control and bed reduction]. PMID- 6925409 TI - [Learning by touch - aspects of the development of visually handicapped children]. PMID- 6925410 TI - [Geriatric visit: 'fragile lives in old age']. PMID- 6925412 TI - [Nursing ethics and nursing education. II]. PMID- 6925413 TI - [GVO (health education)--what exactly is it?]. PMID- 6925411 TI - [Resignation and what's involved in it]. PMID- 6925414 TI - [Health guidance and education in nursing]. PMID- 6925415 TI - [Do you know what catheterization is?]. PMID- 6925417 TI - [Guidance--knack or knowledge?]. PMID- 6925416 TI - [Carrying out health guidance and education in home care services]. PMID- 6925418 TI - [Prevention from the viewpoint of ambulatory health care]. PMID- 6925419 TI - [Service to nurses]. PMID- 6925420 TI - [Report from Brussels]. PMID- 6925421 TI - [Accompanied death: fellow-feeling till the verge]. PMID- 6925422 TI - [Handling panic]. PMID- 6925423 TI - [Geriatric visit: an uncertain equilibrium]. PMID- 6925425 TI - [Attention]. PMID- 6925424 TI - [Poor eyesight, a poor ally]. PMID- 6925427 TI - Mental health attitudes in the OR. PMID- 6925426 TI - An in vivo hamster bioassay to assess the toxicity of particulates for the lungs. PMID- 6925428 TI - Surgical-psychological crisis: awake and paralyzed! PMID- 6925429 TI - Across the table. PMID- 6925430 TI - Interview: Cynthia Porter Hartman. PMID- 6925431 TI - Preoperative visits - controlling the stress. PMID- 6925432 TI - [Effect of dilminal D on the hemodynamics in hypertension]. PMID- 6925433 TI - The critical nurse: sex and politics. PMID- 6925434 TI - A benefit of continuing education: increased self-esteem. PMID- 6925435 TI - [Drug-induced improvement of sperm quality]. PMID- 6925436 TI - [Pneumothorax in lung disease following pancreatin dust exposure]. PMID- 6925437 TI - [Studies on the plasminogen activating system in human milk. VI. Differences in properties between milk activator and glandular kallikrein]. PMID- 6925438 TI - Office nurses are nurses too. PMID- 6925439 TI - Quality assurance - what can it do for the nurse? PMID- 6925440 TI - Definition of nursing/exclusive practice. PMID- 6925442 TI - Hospital child care centers open to retain staff. PMID- 6925441 TI - Activation of the kallikrein-kinin system in premature infants with respiratory distress syndrome (RDS). AB - Plasma prekallikrein levels, kallikrein activity and antikallikrein levels were investigated in nine premature infants with respiratory distress syndrome (RDS) and six premature infants without. Plasma prekallikrein and kallikrein were determined with a chromogenic substrate measuring amidolytic activity. Antikallikrein was measured with a functional assay. In infants with severe RDS, prekallikrein levels were significantly reduced (median 58% of initial values (p less than 0.01) about 48 hours after onset of symptoms. In infants with moderate RDS prekallikrein level was reduced less, while in babies without RDS there were no significant changes in prekallikrein levels the first 5-7 days of life. Antikallikrein levels did not change significantly in any babies. The results suggest that the kallikrein-kinin system might be involved in RDS. This could explain several features of this syndrome such as hypotension and edema. Furthermore the findings show that homeostatic functions are altered in this disease, and they suggest that other cascade systems as the coagulation, fibrinolytic and complement system may be involved as well. The findings emphasize that trauma might be a significant pathogenetical factor for development of this syndrome and indicate that RDS is not simply a biochemical disease with lack of surfactant as the only pathogenetic factor. PMID- 6925443 TI - Ultrasound scanners most effective with mammograms. PMID- 6925444 TI - Nursing ethics: a timely subject for continuing education. PMID- 6925445 TI - Effect of fathers at cesarean birth on postpartum infection rates. PMID- 6925447 TI - Internship prepares perioperative nurses. PMID- 6925446 TI - Cesarean birth in the operating room. PMID- 6925448 TI - Transcriptional control of ribosome production in regenerating rat liver. AB - Kinetic experiments of labelling in vivo with [14C]orotate of cellular free UMP and/or UTP, nucleolar, nucleoplasmic and cytoplasmic rRNA in normal and 12 h regenerating rat liver were performed. The specific-radioactivity curves obtained were analysed by computer and the rates of synthesis of precursor rRNA (45S pre rRNA) and cytoplasmic 28S and 18S rRNA calculated. (a) The rates of synthesis of 45S pre-rRNA in normal and regenerating rat liver are 1400 and 3700 molecules/min per nucleus respectively; (b) the average rates of formation of mature 28S and 18S rRNA are identical with the rates of synthesis of 45S pre-rRNA in both normal and regenerating rat liver. Thus the synthesis of rRNA in 12h-regenerating rat liver is activated 2.7-fold. The analysis of rRNA synthesis in isolated nucleoli also shows a 2.7-fold stimulation of transcription in regenerating liver. It is concluded that all the 45S pre-rRNA molecules synthesized are processed and transferred as 28S and 18S rRNA in the cytoplasm, i.e. degradation (wastage) of newly synthesized ribosomes in the nucleus does not occur in both normal and regenerating rat liver. Thus the enhanced production of ribosomes in regenerating rat liver is regulated only at the transcriptional level. PMID- 6925449 TI - Salvage of the nucleic acid base queuine from queuine-containing TRNA by animal cells. PMID- 6925452 TI - Controlling rubella and hepatitis. PMID- 6925451 TI - Identification of a selenocysteine-specific aminoacyl transfer RNA from rat liver. AB - The aminoacylation of rat liver tRNA with selenocysteine was studied in tissue slices and in a cell-free system with [75Se]selenocysteine and [75Se]selenite as substrates. [75Se]Selenocysteyl tRNA was isolated via phenol extraction, 1 M NaCl extraction and chromatography on DEAE-cellulose. [75Se]Selenocysteyl tRNA was purified on columns of DEAE-Sephacel, benzoylated DEAE-cellulose and Sepharose 4B. In a dual-label aminoacylation with [35S]cysteine, the most highly purified 75Se-fractions were greater than 100-fold purified relative to 35S. These fractions contained less than 0.7% of the [35S]cysteine originally present in the total tRNA. When [35Se]selenocysteyl tRNA was purified from a mixture of 14C labeled amino acids, over 97% of the [14C]aminoacyl tRNA was removed. The [75Se]selenocysteine was associated with the tRNA via an aminoacyl linkage. Criteria used for identification included alkaline hydrolysis and recovery of [75Se]selenocysteine, reaction with hydroxylamine and recovery of [75Se]selenocysteyl hydroxamic acid and release of 75Se by ribonuclease. The specificity of [75Se]selenocysteine aminoacylation was demonstrated by resistance to competition by a 125-fold molar excess of either unlabeled cysteine or a mixture of the other 19 amino acids in the cell-free selenocysteine aminoacylation system. PMID- 6925450 TI - Isolation of inactive kallikrein from rat urine. PMID- 6925453 TI - SAND: when loss is truly hard. PMID- 6925454 TI - Education and service united. PMID- 6925455 TI - Stop! Look! Listen! PMID- 6925456 TI - Fantasy role - play in psychotherapy. PMID- 6925457 TI - Schizophrenia: a disease of the young? PMID- 6925458 TI - Touch - the silent language that reveals all. PMID- 6925459 TI - Immune reaction of tumor-bearing mice to Propionibacterium acnes and the antitumor effect of the bacteria. AB - The relationship between immunological reaction to Propionibacterium acnes (PA) and the antitumor effect of the injected bacterium was investigated. The aim was to determine whether the strength of the immune reaction to the bacterium can be used to predict its antitumor effectiveness. C3Hf/Sed mice received SC injections (right thigh) of viable cells of a methylcholanthrene-induced fibrosarcoma. When the tumor grew to 5 mm, the hosts received 350 micrograms PA IV as the antitumor treatment. Cellular immunity (footpad test) to PA was assayed in one group of these mice 14 days later, and in the other anti-PA agglutinins were determined 28 days later. The PA injection cured 22 of 58 mice in the first, and 20 of 46 mice in the second group. Footpad reaction and agglutinin titers to PA in cured mice were not statistically different from those in mice eventually killed by the tumor. Therefore, the strength of the immune reaction to PA in tumor-bearing mice could not be used to predict the antitumor effectiveness of the bacterium. PMID- 6925460 TI - Modification of cell cholesterol content of rat tumour cells. Effect upon their tumorigenicity and immunogenicity. PMID- 6925462 TI - [The importance of study]. PMID- 6925461 TI - Enhancement of delayed cutaneous hypersensitivity in untreated cancer patients given a short-term oral treatment with C 1821. AB - C 1821 is a purified glycoprotein extract of Klebsiella pneumoniae serotype 2 with immunomodulating properties in animals (in vivo and in vitro) and in humans (in vitro). The compound is devoid of any apparent toxicity when given orally. The aim of the present work was to evaluate the effects of a short term oral administration of C 1821 on delayed cutaneous hypersensitivity to recall antigens in untreated cancer patients (mostly lymphomas). Consecutive patients were alternately allocated to receive C 1821 or placebo for 14 days. C 1821 restored and significantly (P less than 0.02) enhanced skin reactions, as shown using the Multitest system. PMID- 6925464 TI - [On nursing responsibility]. PMID- 6925463 TI - [Systemic engineering in nursing management]. PMID- 6925465 TI - [Application of statistic data in nursing care]. PMID- 6925466 TI - [How supervising nurses play their role in improving nursing care]. PMID- 6925468 TI - [Experience in managing the operating room]. PMID- 6925467 TI - [Cleaning squad and hygienic work]. PMID- 6925470 TI - [Outpatient department management and polite service]. PMID- 6925471 TI - [Nursing of patients with high altitude coma]. PMID- 6925469 TI - [Rapidity and quality in emergency treatment]. PMID- 6925472 TI - [Experience in nursing 363 cases with cerebral hemorrhage]. PMID- 6925473 TI - [Observation of patients with heart diseases before death]. PMID- 6925474 TI - [Sterilization and isolation of patients with positive HBsAg in the operating room]. PMID- 6925476 TI - [Pre- and postoperative care of 64 patients with chronic constrictive pericarditis]. PMID- 6925475 TI - [Patient care after dissolving and vibration treatment for postoperative residual hepatocholangiolithiasis]. PMID- 6925477 TI - [Care of patients with pseudomembranous enteritis after chemotherapy]. PMID- 6925478 TI - [Education in a pediatric ward]. PMID- 6925480 TI - [Relationship between fibrogastroscopic examination-induced complications and nursing]. PMID- 6925479 TI - [Oral "P.A. syrup" as a premedication for fibrogastroscopy]. PMID- 6925481 TI - [Nursing student's medical practice]. PMID- 6925482 TI - [A teacher's personal experience in running a nursing class]. PMID- 6925483 TI - [Ultrasound in clinical diagnosis (1)]. PMID- 6925484 TI - [Drug tolerance variability in bacteria]. PMID- 6925485 TI - [The availability of nurses for the delivery of a comprehensive health service]. PMID- 6925486 TI - The dependent, independent and interdependent functions of the nurse practitioner -a legal and ethical perspective. PMID- 6925487 TI - [Data collection in research: the questionnaire, interview and checklist]. PMID- 6925488 TI - A study into ward traffic. PMID- 6925489 TI - [Sarcoptes infestation (scabies)]. PMID- 6925490 TI - Staff development and education. PMID- 6925492 TI - [School leavers' attitude to nursing]. PMID- 6925491 TI - The role of the unit sister--emphasis on quality of care and accountability. PMID- 6925493 TI - An example of a self-instructional teaching unit for nursing students. PMID- 6925495 TI - Care study - venous ulcers. A lot of care. PMID- 6925494 TI - [The burnout phenomenon in today's professional]. PMID- 6925496 TI - The Quality of Life Committee. PMID- 6925497 TI - Helpful hints. Using a single transducer to monitor two hemodynamic pressure lines. PMID- 6925498 TI - Pediatric cardiac catheterization: Complications and interventions. PMID- 6925499 TI - The "Logan bow" method for securing endotracheal tubes in neonates. PMID- 6925500 TI - Intraventricular conduction blocks. Part I. Introduction and electrocardiographic identification of right and left bundle branch block. PMID- 6925502 TI - A step-by-step approach for calculating intravenous medications. PMID- 6925501 TI - Are you listening? PMID- 6925503 TI - Complications of myocardial infarction. PMID- 6925504 TI - The role of potassium in health and disease. PMID- 6925505 TI - Drug corner. Bactrim I.V. infusion. PMID- 6925506 TI - The legalities of critical care. Hospital policy: to follow or not to follow. PMID- 6925507 TI - Arrhythmia quiz. PMID- 6925508 TI - The phrenic nerve stimulator. PMID- 6925509 TI - How to develop a critical care nursing course. PMID- 6925510 TI - The legal liabilities of critical care. PMID- 6925511 TI - EKG of the month. PMID- 6925514 TI - Are you listening? Acute heat stroke. PMID- 6925512 TI - Arrhythmia quiz. PMID- 6925515 TI - Pavulon (pancuronium bromide). PMID- 6925513 TI - Pharmacologic paralysis. PMID- 6925516 TI - Care of the patient on the percutaneous intra-aortic counterpulsation balloon. PMID- 6925517 TI - The patient on the intra-aortic balloon pump. PMID- 6925518 TI - Caring and sharing: neonatal nursing. Maintaining the infant's skin integrity. PMID- 6925519 TI - Motivating critical care nurses through peer evaluation. PMID- 6925520 TI - Intraventricular conduction blocks. Part II.--Axis calculation and electrocardiographic identification of left anterior fascicular block and left posterior fascicular block. PMID- 6925521 TI - Establishing a critical care unit orientation program. PMID- 6925522 TI - Nursing care plan for MI patients. PMID- 6925523 TI - Performance appraisal of staff nurses - Part II. Analyzing the old and planning for the new. PMID- 6925525 TI - Assessment of the teratogenicity of ammonium vanadate using Syrian golden hamsters. PMID- 6925524 TI - Your mystery arrhythmia strips. PMID- 6925526 TI - Investigations into various pancreatic enzymes. AB - The effects of several pancreatic enzymes on living tissue incapable of autodigestion were studied to analyse elements of the "pluralistic events of acute hemorrhagic pancreatitis" (Becker 1981). Phospholipase A2 induces (via toxic lysolecithin) cytotoxic necrosis in the testis; elastase (via destruction of vessels and local ischemia) causes hypoxic necrosis. Injection of lipase does not result in necrosis. PMID- 6925527 TI - [Prevention of rabies]. PMID- 6925528 TI - [Thrombocytopenic purpura in children]. PMID- 6925529 TI - [Large fetus]. PMID- 6925530 TI - [Examination for gonorrhea and the treatment of chronic inflammatory diseases of the female genitalia]. PMID- 6925531 TI - [Allergic dermatitis]. PMID- 6925532 TI - [Organization of ambulatory polyclinic care in the USSR]. PMID- 6925533 TI - [First aid in acute coronary failure (material for talks)]. PMID- 6925534 TI - [Hygiene for the pregnant woman (material for talks)]. PMID- 6925535 TI - [Health education of hairdressers]. PMID- 6925536 TI - [Torsion of the peduncle of an ovarian cystoma]. PMID- 6925537 TI - [Myocardial infarct]. PMID- 6925538 TI - [Wrinkles (or, how to prevent premature withering of the skin)]. PMID- 6925540 TI - [Hypertensive syndrome in children]. PMID- 6925539 TI - [Comparative evaluation of diagnostic methods in diphyllobothriasis]. PMID- 6925542 TI - [Parkinsonism]. PMID- 6925544 TI - [Comprehensive provision of safety in swimming for nursing infants]. PMID- 6925543 TI - [Stomach cancer]. PMID- 6925541 TI - [Bronchiectatic disease]. PMID- 6925545 TI - [Current status of traumatology and orthopedics]. PMID- 6925549 TI - [Bronchial asthma attack. Chronic pneumonia and pulmonary emphysema]. PMID- 6925550 TI - [Use of aerosols in respiratory organ diseases]. PMID- 6925546 TI - [Conducting theoretical and practical exercises in a medical first aid course]. PMID- 6925547 TI - [Thrombocytopenia and pregnancy]. PMID- 6925548 TI - [Climacteric cardioneurosis]. PMID- 6925551 TI - [Indices of the level of the organization of intestinal infection control]. PMID- 6925552 TI - Nursing: shortage or surplus? PMID- 6925553 TI - Highlights of the Georgia Nurses Association in action 1907-1982. PMID- 6925555 TI - [Late cardiac sequelae in children following long-term tocolysis with fenoterol and verapamil]. AB - Premature labour has been treated with Fenoterol and Verapamil since 1970 in the Working Team of Perinatal Medicine of Berlin Free University/Municipal Gynaecological Clinic at Berlin-Neukolln. Elective necroses of the myocardial fibres after stimulation with high concentrations of beta 2-sympathicomimetics have been demonstrated in animal experiments and in isolated foetal myocardial preparations in vitro. It is claimed that such lesions can be avoided by the additional administration of Ca2+ antagonists. Fenoterol and Verapamil will pass the placental barrier. In order to clarify whether long-term tocolysis may exercise an effect on the foetal myocardium, the authors examined 140 children. 78 children of mothers treated with long-term tocolysis were compared with 62 children of mothers who had not received such treatment. The systolic time intervals were measured in full-term children born between 1970 and 1974 and aged 6 to 10 years. Following recording of the case history and physical examination, the ECG, phonocardiogram as well as the carotid sphygmogram were recorded. The frequency rate of abnormal ECG findings (RVL, AV block of the first degree, WPW syndrome) in the tocolysis groups did not differ from that of the untreated control group. Besides, the myocardial contractilities of both groups were also not different from each other. PMID- 6925554 TI - [Cryoconservation of 8-celled stage rabbit embryos in an automated "open system"]. AB - Rabbit embryos were successfully frozen at the 8-cell stage, employing a rapid and a slow freezing-thawing program. They were then stored at -196 degrees C (liquid nitrogen) for 10 to 60 days. After thawing the embryos were examined for viability in vitro and in vivo. Using the slow program B 82.5% were morphologically intact, compared to only 69.3% after the rapid procedure (program A). 88.8% of the group first mentioned above, and 56.8% of the latter developed to the blastocyst stage after 4 to 5 days in culture. The implantation rate was 18.1%, when embryos were transferred to minus 18 hours asynchronous recipients, after thawing. With 40%, a significantly higher implantation rate could be achieved, when the embryos were transferred to minus 24 hours asynchronous foster mothers. 18 viable young were born 30 to 32 days after transfer. PMID- 6925556 TI - [HBs-antigen determination during pregnancy with reference to prevention of a postnatal infection in the newborn infant]. AB - In 1980 and 1981 the blood samples of 2040 pregnant women from the Department of Obstetrics of the University Hospital of Cologne have been examined for HBs antigen. In 37 samples (1.8%) HBs-antigen was detected. As there are considerable racial as well as geographic differences in the frequency of HBs-antigenemia, we differentiated between German and foreign women. In 10 out of 1519 (0.7%) German and in 27 out of 521 (5.2%) foreign women, respectively, HBs-antigen could be demonstrated. Only 1 woman was known to be HBs-antigen positive. Until now, 38 children have been born in the University Hospital to 33 HBs-antigen-positive mothers. After birth, 35 children received hepatitis B immune globulin (HBIG). So far, none of these immunised children exhibited signs of a hepatitis B infection- 22 children have been followed up 5-19 months, and 13 children 1-4 months. Three newborns did not receive HBIG: One child was already infected at time of birth, the 2 other children were erroneously not given HBIG. One of these 2 children fell ill at the age of 5 months with clinical and serological manifestations of hepatitis B, the other child appears healthy up to date (11 weeks). PMID- 6925557 TI - [The risk of dihydroergotamine treatment in pregnancy]. PMID- 6925559 TI - [The differential diagnosis of tumors of the mamilla and the areola of the breast]. AB - Tumourous changes of the mamilla and the areola of the breast are rare compared to tumours of the glands of the breast. Although these tumours are rare a large number of possible tumours occur in this area. The differential diagnosis is therefore difficult. A survey of the possible tumours is given in tables and macroscopic pictures. The macroscopic similarity of the adenoma of the mamilla with primary cancer of the mamilla and pagets disease of the mamilla are stressed. The possibility of tumour like swellings which are not neoplastic is described. Among these pseudotumours locally infected conditions are predominant. Any tumour in the mamilla or areola which cannot be diagnosed with certainty must be subjected to microscopic tissue diagnosis. PMID- 6925558 TI - [Ectopic pregnancy: diagnostic reliability of a new hCG-test (Neo-Pregnosticon)]. AB - We report about the diagnostic reliability of a new commercially available human chorionic gonadotropin (hCG) test, a simple hemagglutination test (discriminatory value: 75 U/I), which can be easily performed in any laboratory (Neo Pregnosticon). Urine samples of 457 patients with unexplained lower abdominal pain and/or abnormal bleeding were analysed. The diagnostic sensitivity and specificity of the test gave values of 0.993 and 1.0, respectively. The predictive value for positive results was 1.0, and for negative results 0.997. By means of this test, we could determine hCG in urine of 40 out of 41 patients with ectopic pregnancy, in contrast to the currently used urine test (Pregnosticon, discriminatory value: 1000 U/I) which was positive in only about 50% of the cases. Due to its accuracy, this simple test will probably replace in the future the more laborious radioimmunological methods for determination of hCG. PMID- 6925560 TI - [Estrogen and progesterone receptors in corpus uteri carcinoma and their clinical significance]. AB - In 49 carcinomas of the endometrium of varying clinical stages the estrogen and progesterone receptors were studied by charcoal absorption methods. The cases were studied between 1979 and 1981. 64% of the investigated cases were receptor positive, 35% were receptor negative. Estrogen receptors were detected in 61% and progesterone receptors in 49% of the cases. Both estrogen and progesterone receptors were detected in 45% of the cases. The receptor status was correlated with the clinical stage, the microscopic differentiation and the age of the patient. In 30 cases with a follow-up of more than 3 months it was attempted to determine the prognostic value of the steroid receptor status in endometrial carcinoma. The treatment possibilities with progestational agents and antiestrogens and with tamoxifen were discussed in view of the receptor status. PMID- 6925561 TI - [Radiological documentation of morphological changes following colporrhaphy]. PMID- 6925563 TI - [The concept of health]. PMID- 6925564 TI - [The red corpuscle: life and death]. PMID- 6925562 TI - Nucleotide sequence of Rattus norvegicus mitochondrial DNA that includes the genes for tRNAile, tRNAgln and tRNAf-met. AB - The nucleotide sequence of a segment of mtDNA from Rattus norvegicus (rat) which contains the genes for tRNAile, tRNAgln and tRNAf-met has been determined. A detailed comparison has been made between this sequence and the corresponding sequences of mouse, human and bovine mtDNAs with regard to the primary and secondary structure of the tRNA genes, the regions connecting the tRNA genes, and the regions flanking the tRNA genes which code for the carboxyl terminus of URF-1 and the amino terminus of URF-2. No differences were found in the nucleotide sequences of the genes for tRNAile, tRNAgln and tRNAf-met in mtDNAs from three different female lines of rats (SASCO-1, SASCO-2 and Wild-UT) that differ by substitutions of 0.8% to 1.8% of their total nucleotides. PMID- 6925565 TI - [The nurse faced with the anxiety of the coronary patient, in an intensive care unit]. PMID- 6925567 TI - Are health visitors politically naive? The Marjory Turner Memorial session. PMID- 6925566 TI - The sacrament of the anointing of the sick: theology. PMID- 6925568 TI - National cohort studies--the facts about Britain's children. PMID- 6925570 TI - NHS pay--a completely different aspect. PMID- 6925571 TI - Will the Barclay Report change the face of social work? PMID- 6925569 TI - Pertussis immunization--current knowledge and recommendations. PMID- 6925572 TI - The effect of severe weather upon the elderly in two areas in South Wales. PMID- 6925573 TI - Health visitors--a tribute from a mother. PMID- 6925574 TI - New approaches in health visiting. 3: Caseload profiles: their implications for evaluating health visiting practice. PMID- 6925575 TI - Immunizing infants at high risk of hepatitis B. PMID- 6925576 TI - The effect of cimetidine on meal-stimulated gastric function and exogenous pancreatic enzymes in cystic fibrosis. AB - Some patients with cystic fibrosis (CF) have malabsorption of fat and protein in spite of large amounts of supplemental pancreatic enzymes. This is partly due to acid inactivation of exogenous pancreatic enzymes in the stomach. The effect of cimetidine on gastric function and exogenous pancreatic enzymes was assessed by a marker perfusion technique in 4 CF children in a double-blind controlled fashion. Gastric acid secretion was higher in CF patients than in controls (P less than 0.005) and was reduced significantly by oral cimetidine (P less than 0.02). Rapid inactivation of exogenous trypsin and lipase occurred when gastric pH fell to less than 4.5. There was no loss of enzyme activity during treatment with cimetidine when gastric pH remained above 5.5. Activity of lipase and trypsin in the jejunum improved in all subjects. Fat and nitrogen absorption assessed by a balance technique during the study period showed a small improvement in fat absorption while on cimetidine. We conclude that some CF patients have a high meal-stimulated gastric acid output which causes inactivation of trypsin and lipase. Cimetidine was effective in reducing acid secretion in such patients and led to small improvements in fat absorption. PMID- 6925577 TI - [Increased incidence of tissue rupture with pudendal block for delivery?]. PMID- 6925579 TI - [Management of breech presentation]. PMID- 6925578 TI - [Scholarship report: study trip to the USA]. PMID- 6925580 TI - [Scholarship report: from the 5th World Congress on Ultrasound in medicine and Biology]. PMID- 6925581 TI - A new fast variant (BF*F08) of the BF polymorphism. PMID- 6925582 TI - Image Intensifying systems. Part II. The primary equipment for on-going visualization of surgery. PMID- 6925583 TI - Valley Hospital, Ridgewood, NJ. PMID- 6925585 TI - Operating room tables. PMID- 6925584 TI - IV systems--sequel. PMID- 6925587 TI - Rx for burn-out. PMID- 6925586 TI - Urinary drainage need not lead to U.T.I. PMID- 6925589 TI - The dilemma--hepatitis B. What is it all about? PMID- 6925590 TI - Two-dimensional technique to calculate the EM power deposition pattern in the human body. AB - A numerical procedure to calculate the electromagnetic (EM) power deposition in two-dimensional models of cross sections in the human body is described. The procedure involves obtaining X-ray images of cross sections of specific areas with computer axial tomographic scans and then solving the EM boundary value problem by using the method of moments. The formulation thus takes into account not only the spatial distribution of the different tissue types, but also the radiation characteristics of the typical EM source. Numerical results are given to illustrate the accuracy of the developed procedure. Special emphasis is placed on characterizing and analyzing the EM power deposition patterns obtained using the annular phased array system recently developed by BSD Medical Corporation for hyperthermia treatments. PMID- 6925591 TI - An empirical time-intensity relationship for thermal bioelectromagnetic effects. AB - Published experimental data for three thermal/harmful bioelectromagnetic effects (lethality, cataractogenesis, and threshold pain sensation) are examined in an effort to develop a generally consistent empirical expression relating the time of irradiation necessary to induce an effect to the intensity of the radiation. A critical organ is assigned to each effect and the SAR's in these organs are estimated, when necessary, from the incident power density. It is found that all the data can be satisfactorily described by a single power function expression which gives the exposure duration as a function of the SAR in the critical organ and an experiment-specific constant. PMID- 6925592 TI - Radiofrequency-induced hyperthermia in the prostate. AB - A high frequency radiator has been developed for the treatment of prostate cancer by hyperthermia. The applicator produces a deep seated hot spot. The radiator has an outer diameter of 20 mm and an insertable length of about 175 mm. A high frequency cylindrical slot antenna inside the applicator is cooled by water. The frequency used is 433.9 MHz, one of the frequencies allowed for medical therapy in the F.R.G. A control system regulating the power output of the radiator avoids damage to the tissue around the prostate, especially the rectum mucosa and the tissue between rectum and prostate. About 60 experiments with male dogs proved that local heating of the prostate is possible with the help of the developed applicator without any damage in the surrounding tissue. PMID- 6925588 TI - Brookhaven Memorial Hospital Medical Center (BMHMC) Patchogue, NY. PMID- 6925593 TI - Exposure of rats to 425-MHz (cW) radiofrequency radiation: effects on lymphocytes. AB - Four experiments were performed in which six pregnant rats were exposed from day 12 of pregnancy to parturition, for 4 hours a day in a temperature-controlled environment, to 425-MHz (CW) radiation, using a multimode rectangular strip transmission line. Four male pups born to each dam were subsequently irradiated under the same RF exposure condition for 20-21 days of age (2 pups) and 40-41 days of age (2 pups). Specific absorption rates (SARs) for rats of different ages were determined by twin-well calorimetry as well as from calculations of power measurements of incident, reflected, and transmitted energy. Values of SARs between 3.1 and 6.7 mW/g were obtained for rats so exposed at 425 MHz. At selected times, rats were weighed to determine if the irradiation affected growth. Two rats from each litter (4 pups) were euthanized at 20-21 and two at 40 41 days of age and blood was obtained for complete blood counts. The in vitro blastogenic response of blood and lymph-node lymphocytes was measured by 3H thymidine incorporation into DNA following stimulation of cells with T- or B lymphocyte mitogens. No difference was observed in the weights of irradiated compared with sham-irradiated rats. No consistent change in the peripheral blood picture was observed between irradiated and sham-irradiated rats. Significant increases in the response of lymph-node but not of blood lymphocytes from irradiated rats following stimulation with mitogens was observed in two of four experiments. These changes were observed for both T- and B-lymphocytes. In another experiment at the same frequency, six pregnant rats were irradiated for 16 hours daily from day 6 through day 19 of pregnancy. The pups born to these dams were not subsequently irradiated. These rats, born to irradiated dams, showed a similar increased response of node but not of blood lymphocytes to T cell mitogens at 42 days of age. These results indicate that exposure to 425-MHz microwave radiation, under the conditions described, may lead to increased responsiveness of node lymphocytes to in vitro stimulation by mitogen. PMID- 6925594 TI - A radio-frequency monitor for protection against overexposure from RF heaters. AB - Extensive investigation on the various potentially polluting RF sources has led to the conclusion that the largest proportion of problems arising from possible RF hazards originates from industrial heating machines (short-wave). In particular, these turn out to require checks due to their intrinsic and induced instabilities. Through the analysis of RF leakage characteristics of these machines, the problem is simplified and the solution is presented in terms of an RF hazard monitor which can be used by non-specialized personnel. The monitor is also suitable for several other types of potentially dangerous apparatus in the medium- and short-wave range. PMID- 6925595 TI - The team approach in primary health care. PMID- 6925597 TI - The process of evaluation. PMID- 6925596 TI - Problem solving. PMID- 6925598 TI - Quality assurance in the clinical area. PMID- 6925599 TI - Address by the Prime Minister of the Commonwealth of the Bahamas at the 13th biennial conference and 25th anniversary of the Caribbean Nurses' Organization, 27th June, 1982. PMID- 6925600 TI - A theological perspective. PMID- 6925601 TI - Mental health and the family. PMID- 6925602 TI - Social worker and mental health. PMID- 6925603 TI - Nurses and mental health. PMID- 6925604 TI - [Standards of observation immediately after patients' arrival - vital signs and the standard of nursing observation]. PMID- 6925607 TI - [Emergency nursing standards. Acute respiratory insufficiency and respiratory arrest]. PMID- 6925606 TI - [Emergency examination and nursing sequence. The blood and urine]. PMID- 6925605 TI - [Emergency examination and nursing sequences. Radiography, CT scan, central venous pressure, and Swan-Ganz catheter]. PMID- 6925608 TI - [Emergency nursing standard. Heart arrest and cardiopulmonary resuscitation]. PMID- 6925610 TI - [Emergency nursing standard. Hypovolemic shock - with special reference to hemorrhagic shock]. PMID- 6925609 TI - [Emergency nursing standard. Cardiogenic shock]. PMID- 6925613 TI - [Emergency nursing standard. Acute abdomen (intestinal perforation and obstruction)]. PMID- 6925612 TI - [Emergency nursing standard. Diabetic coma and hepatic coma]. PMID- 6925614 TI - [Emergency nursing standard. Multiple injuries]. PMID- 6925615 TI - [Emergency nursing standard. Burns - nursing during the first 48 hours following admission]. PMID- 6925611 TI - [Emergency nursing standard. Acute arrhythmia]. PMID- 6925616 TI - [Emergency nursing standard. Acute renal failure]. PMID- 6925617 TI - [Emergency nursing standard. Acute poisoning]. PMID- 6925620 TI - [Cancer and viruses. A discussion]. PMID- 6925618 TI - [Emergency nursing standard. Apoplexy]. PMID- 6925619 TI - [Bacteriological study on oral hygiene and the effects of several antiseptic agents]. PMID- 6925621 TI - [Professional development to be achieved by nursing instructors]. PMID- 6925622 TI - [Re-evaluation of continuing education in nursing]. PMID- 6925624 TI - [The 13th meeting of the Japan Nursing Association Education Section: with a theme of "education to heighten independence of nursing"]. PMID- 6925623 TI - [News report. Establishment of a flexible curriculum for nursing education: opening of the first curriculum committee meeting for the Nursing Section of the National University Junior Technology Colleges]. PMID- 6925625 TI - [On nursing education. 5. The status of nursing education in the United States and England. (2)]. PMID- 6925626 TI - [In search of educational humanity. (11). Theories on teachers. 2]. PMID- 6925627 TI - [Keypoints in observation of infants - for clinical training of the public health nursing students]. PMID- 6925629 TI - [Study on the bag used by home-visiting public health nurses]. PMID- 6925628 TI - [Role of the public health nurse in regional maternal and infant care - a trial application of the focal points in infant examination]. PMID- 6925630 TI - [Status of senile patients and their families: the second nationwide survey conducted by the organization of families caring for senile patients]. PMID- 6925631 TI - [The father, a very important figure if breast feeding is to succeed. A successful Tampere project]. PMID- 6925633 TI - [Selective vaccination against German measles for puerperal patients]. PMID- 6925632 TI - [Child psychiatry consultant in the neonatal ward, a help for parents and personnel]. PMID- 6925634 TI - [We midwives are staging a comeback]. PMID- 6925635 TI - [Pregnancy and asthma]. PMID- 6925636 TI - [Increased knowledge - a prerequisite for effective self care]. PMID- 6925637 TI - Developmental aspects of the renal kallikrein-like activity in fetal and newborn lambs. AB - The ontogeny of the renal kallikrein-like activity and the interrelationships between this enzyme and the renin-angiotensin-aldosterone and prostaglandin systems were studied in 43 chronically catheterized sheep fetuses between 104 and 142 days of gestation (term, 145 days) and in 8 chronically catheterized newborn lambs between 5 and 23 days of age. Urinary kallikrein (UKall) excretion rate expressed in absolute values (mEU/hr) or corrected for kidney weight (mEU X hr-1 X gKW-1) or glomerular filtration (mEU X hr-1 X ml GFR-1) increased significantly during fetal maturation and after birth. The rise in UKall during fetal and newborn life was not dependent on an increase in urinary flow rate (r = 0.06). The increase in fetal UKall (mEU X hr-1 X gKW-1) correlated closely with the rise in plasma aldosterone concentration for values above 35 pg/ml (r = 0.72, P less than 0.001). A significant negative correlation was found between UKall (mEU X hr 1 X gKW-1) and log of individual urinary sodium excretion values (r = -0.78, P less than 0.001). No correlation was found between UKall and urinary prostaglandins (PGE, PGF2 alpha) excretion during fetal and newborn life, but UKall correlated closely with the rise in renal blood flow during maturation (r = 0.87, P less than 0.001). The present data suggest that aldosterone is an important regulator of UKall release early during development. It is also suggested that conceptional age is an important factor which may modulate the renal sensitivity to aldosterone-stimulated UKall excretion. PMID- 6925640 TI - [Understanding of variables affecting level of pain]. PMID- 6925639 TI - The measurement of amidolytic activity in kidney homogenates for the estimation of renal kallikrein. PMID- 6925641 TI - [Study on the preventive health behavior patterns in the rural community]. PMID- 6925638 TI - Localization of active and inactive kallikrein (kininogenase activity) in the microdissected rabbit nephron. AB - Active and total (trypsin-activated) kallikrein were measured in discrete segments of the nephron by their kininogenase activity. The kinins generated were measured by radioimmunoassay and the amount of inactive kallikrein was calculated as the difference between total and active kallikrein. Single nephrons from collagenase-treated rabbit kidneys (N = 12) were microdissected and divided into eight segments: (1) glomerulus; (2) proximal convoluted tubule; (3) cortical thick ascending limb; (4) bright portion of distal convoluted tubule; (5) granular portion of distal convoluted tubule; (6) granular portion of cortical collecting tubule; (7) light portion of cortical collecting tubule; and (8) medullary collecting tubules. After pooled segments (approximately 50 nephron segments in each assay) were homogenized and treated with deoxycholic acid, active and total kallikrein were measured and inactive kallikrein was calculated. Active and inactive kallikrein were localized in granular portions of the distal and cortical collecting tubule, which contains more than 85% of the active and inactive kallikrein found in the total microdissected nephron. Little or no kallikrein was detected in other segments, including the bright portion of the distal segment which has the macula densa. The discrete localization of active and inactive kallikrein suggests a specific role for renal kallikrein in these nephron segments. PMID- 6925642 TI - [Seminar on nursing administration]. PMID- 6925643 TI - [A study on mental health condition in non-nursing and nursing women students]. PMID- 6925644 TI - [What kind of nurses are needed for today and tomorrow's Korean society]. PMID- 6925645 TI - [What changes should be made in curriculum of nursing education for the nurses?]. PMID- 6925646 TI - [Seminar on nursing education for the future. What changes in laws and policies would be required?]. PMID- 6925647 TI - [Health & problems of adults and their nursing care]. PMID- 6925649 TI - [A baseline study on clinical practice education of community health nursing]. PMID- 6925648 TI - [Prevention & control of viral hepatitis in adult]. PMID- 6925650 TI - [Seminar on nursing education for the future]. PMID- 6925651 TI - [A study on hospital nurses' attitudes of nursing autonomy and patients' rights]. PMID- 6925652 TI - [A study on infection management in hospitals]. PMID- 6925654 TI - [Truth at the deathbed?]. PMID- 6925653 TI - [Nursing and nursing education for today and tomorrow in Korea]. PMID- 6925656 TI - [Diagnosis and therapy of hemorrhoids]. PMID- 6925657 TI - [Early summer meningitis. Active vaccination now possible]. PMID- 6925655 TI - [The psychiatric department in the general hospital. Report of a meeting in the Institute for Hospital Architecture of the Berlin Technical University 1981]. PMID- 6925658 TI - [Current directions in American nursing]. PMID- 6925659 TI - [Eye surgery: postoperative medication and postoperative bandages]. PMID- 6925660 TI - [Learning on a social ward? Report by a student]. PMID- 6925661 TI - [The status of trauma surgery at the Hannover Medical University]. PMID- 6925662 TI - [Nursing home care]. PMID- 6925663 TI - [Superintelligent--but unrecognized]. PMID- 6925664 TI - [Tips for teachers in nursing schools]. PMID- 6925665 TI - [Report from ophthalmology. The 'eye bank' in Ankara]. PMID- 6925666 TI - [The atomic war and its medical sequelae]. PMID- 6925667 TI - [Measures in respiratory system disorders]. PMID- 6925668 TI - [Prospects in training and continued education in the recession?]. PMID- 6925669 TI - [Fear in our times. What can we do?]. PMID- 6925670 TI - [Nursing process: nursing of patients with heart valve diseases. Physiopathology of heart valve diseases]. PMID- 6925671 TI - [Nursing process: nursing of patients with heart valve diseases. Diagnosis and therapy of heart valve diseases]. PMID- 6925672 TI - [Nursing process: nursing of patients with heart valve diseases. Nursing process for patients with heart valve diseases]. PMID- 6925674 TI - [Nursing process: nursing of patients with heart valve diseases. Evaluation of the nursing process: discussion]. PMID- 6925673 TI - [Nursing process: nursing of patients with heart valve diseases. A case study]. PMID- 6925675 TI - [Bedside tests: keypoints in nursing and interpretation of the data. Neurologic examinations: electroencephalography and electromyography]. PMID- 6925676 TI - [Nursing process: possibilities and limitations in its application. 11. Evaluation of the procedures in each stage: evaluation of the application (3)- implementation and evaluation methods]. PMID- 6925677 TI - [Adverse effects of radiotherapy not associated with other therapeutic modalities for the treatment of cervical cancer (2). A follow-up study of chronic disorders]. PMID- 6925678 TI - [Mastectomy: methods and keypoints in postoperative care]. PMID- 6925680 TI - [Nursing of a patient undergoing mastectomy: a case study]. PMID- 6925681 TI - [Experience in nursing of a patient with breast cancer]. PMID- 6925682 TI - [In search of a new nursing philosophy. XXVI. "Death": attitude of the nursing personnel tailored to individual cases]. PMID- 6925679 TI - [Keypoints in pre- and postoperative nursing of patients undergoing mastectomy]. PMID- 6925683 TI - [Test yourself: a child with Kawasaki disease and assistance for her mother]. PMID- 6925684 TI - [Pathophysiology of burn; thermal injury]. PMID- 6925685 TI - [In search of new concepts in nursing philosophy. Death: assistance for a peaceful journey]. PMID- 6925686 TI - [Test yourself. Pre- and post-operative care of a patient with esophageal cancer]. PMID- 6925687 TI - [Nursing process of burn patients]. PMID- 6925688 TI - [Nursing of thermal injury victims through case examples]. PMID- 6925689 TI - [Nursing studies. Observation--development of the nursing process during the clinical practicum]. PMID- 6925690 TI - [Nursing studies. Reflections on the instruction of "penmanship" training during conversion of preferred hand]. PMID- 6925692 TI - [Surgery: the basic and practical care of cataract surgery]. PMID- 6925691 TI - [Cataract surgery: methods and point of post-operative management]. PMID- 6925694 TI - [Diagnosis and treatment of burns]. PMID- 6925693 TI - [Nursing care of an aging patient with cataract]. PMID- 6925695 TI - [Search for human relationship in nursing--assistance to social rehabilitation of above the knee amputation]. PMID- 6925697 TI - Liability for nursing negligence in the operating room. PMID- 6925696 TI - Wrongful life - its problems are not just semantic: a reply to Furrow. PMID- 6925698 TI - Does hospital corporate liability extend to medical staff supervision? PMID- 6925700 TI - Rights training for providers: education as advocacy. PMID- 6925699 TI - Mississippi University for Women v. Hogan: the Supreme Court rules on female-only nursing school. PMID- 6925701 TI - Community health nurses. PMID- 6925702 TI - The case against the closure of inner metropolitan public hospital beds. PMID- 6925704 TI - Artificial insemination - a new role for nurses in fertility clinics. PMID- 6925703 TI - Crisis: the nurse at risk. PMID- 6925705 TI - Basic nursing education--what's the buzz? PMID- 6925706 TI - Committee of Inquiry into the Recognition of Overseas Qualifications (the Fry Committee). PMID- 6925708 TI - Standardisation of the care of the Hickman catheter. PMID- 6925707 TI - The Third World takes on drug dumping. PMID- 6925710 TI - Agency mergers: a cost-effective approach to improving patient care. PMID- 6925712 TI - Nursing theory as a route to nursing unity. PMID- 6925711 TI - The emerging image. PMID- 6925709 TI - Coronary risk factors in a rural community which includes Aborigines: Inverell Heart Disease Prevention Programme. PMID- 6925713 TI - Problems of parents with a baby in a special care unit. PMID- 6925714 TI - When the patients ask about genital herpes. PMID- 6925715 TI - The dynamics of prejudice. PMID- 6925716 TI - Life on a mission station. PMID- 6925717 TI - Interaction with health care personnel. Part 1. The antenatal period. PMID- 6925718 TI - A comparison of knowledge of coronary risk factors between clients at a secondary level of prevention and a tertiary level of prevention. PMID- 6925719 TI - The balanced future. PMID- 6925720 TI - Minimise needless extravagance. PMID- 6925721 TI - Thompson's hemi arthroplasty. PMID- 6925723 TI - Nursing education challenged. Our undertrained nurses: my turn. PMID- 6925724 TI - The future of video in nurse education. PMID- 6925722 TI - Working longer and loving it? PMID- 6925725 TI - Sorry, he's in a meeting. PMID- 6925726 TI - Legal notes: copyright and video recordings. PMID- 6925728 TI - The management of clinical specialities. 9. A regional paediatric burns unit. PMID- 6925729 TI - Moving into management in an HMO: five nurses from Rose Ross tell their stories. PMID- 6925730 TI - Financial nurse: assessing your total compensation. PMID- 6925731 TI - Exodus of the ICU nurse: the cure is in the cause. PMID- 6925727 TI - Future funding of the NHS. PMID- 6925732 TI - Can unions get you what you want? The case for: unions in our own image. PMID- 6925734 TI - The role and educational needs of OH nurses. 1. Setting the scene. PMID- 6925733 TI - Can unions get you what you want? The case against: nurses and management share common goals. PMID- 6925735 TI - Safety representatives: what they do--and what they would like to do. PMID- 6925736 TI - OH services in the NHS. PMID- 6925737 TI - Safety: preventing gas explosions. PMID- 6925738 TI - Sharps injuries in hospital. PMID- 6925739 TI - The role and educational needs of OH nurses--2. PMID- 6925741 TI - Group therapy at work. PMID- 6925740 TI - Safety: catching them young. PMID- 6925744 TI - Safety: stricter hygiene limits on solvent exposure. PMID- 6925743 TI - The role and educational needs of OH nurses. 3. Role overlap. PMID- 6925746 TI - [Profession and duty]. PMID- 6925745 TI - Implementing a baccalaureate nursing program in rural Oklahoma. PMID- 6925742 TI - OH nursing afloat. PMID- 6925747 TI - [A critical discussion about the service distribution of nursing personnel. 1]. PMID- 6925748 TI - [The psychological situation of the aging persons]. PMID- 6925750 TI - [Research - a challenge to nursing]. PMID- 6925749 TI - [Pedagogical problems in the practical education of student nurses]. PMID- 6925751 TI - [Practical education in nursing education - a real problem? 1]. PMID- 6925753 TI - [The problem of aging. New directions in industrialized countries]. PMID- 6925754 TI - [Devotion--as a sign of hope]. PMID- 6925752 TI - [A critical discussion on the scheduling arrangement of nursing personnel. 2]. PMID- 6925755 TI - [Practical education in nursing education - a real problem? 2]. PMID- 6925758 TI - Increasing our visibility: toward a stronger public image for nursing. PMID- 6925756 TI - [The problem of aging. The role of nursing personnel in geriatric nursing]. PMID- 6925757 TI - Evaluating your continuing education offering. PMID- 6925761 TI - The National Student Nurses' Association: its benefits for students. PMID- 6925760 TI - Visibility of the school of nursing in the community. PMID- 6925759 TI - Nurses and health policy. PMID- 6925762 TI - Nursing grants--what's available and how to secure them. PMID- 6925764 TI - Collaboration among professional colleagues. PMID- 6925763 TI - Grant writing. PMID- 6925765 TI - Policies and procedures of accreditation for programs in nursing education. PMID- 6925766 TI - Cost of nursing education: a manual for analysis of expenditures. Part I. Method, directions, and examples: diploma program. PMID- 6925767 TI - Cost of nursing education: a manual for analysis of expenditures. Part II. Data gathering instruments. PMID- 6925768 TI - Quality circles in nursing service. A step-by-step implementation process. PMID- 6925771 TI - Gastroenteritis in childhood. PMID- 6925770 TI - Myasthenia gravis. PMID- 6925769 TI - An elementary approach to blood gas analysis in respiratory disorders. PMID- 6925772 TI - Occupational health surveillance programmes. PMID- 6925774 TI - Some factors commonly overlooked in bedside monitoring. PMID- 6925773 TI - Cardiac monitoring. PMID- 6925775 TI - Angina pectoris. PMID- 6925777 TI - Psychological aspect in the care of stoma patients. PMID- 6925778 TI - From nurse to nurse about infection. PMID- 6925776 TI - Medical aspects of colostomy. PMID- 6925779 TI - Continuing education for practising nurses. PMID- 6925780 TI - Nurse interaction in research. PMID- 6925781 TI - An intelligent look at managers' intelligence. PMID- 6925783 TI - Add years to life, and life to years. PMID- 6925785 TI - Nursing research. PMID- 6925786 TI - Operational research. PMID- 6925782 TI - Nursing--a challenging profession. PMID- 6925784 TI - The role of professional organizations in nursing advancement. PMID- 6925787 TI - The nurse and research in a hospital setting. PMID- 6925790 TI - Mothers of disabled children: a study of parental stress. PMID- 6925788 TI - Performance appraisal for community health nurses through self-appraisal and goal setting. PMID- 6925789 TI - The role of complex equipment in nurses' work: toward the development of a measure. PMID- 6925791 TI - Institutional collaboration in extending professional educational opportunities for nurses. PMID- 6925793 TI - [Nursing in diabetes]. PMID- 6925792 TI - A clinical instruction observation tool. PMID- 6925794 TI - [Teaching of patients by RNs]. PMID- 6925795 TI - [Nursing in the future by standards of care]. PMID- 6925796 TI - [The importance of instructing children and their parents before elective surgery]. PMID- 6925797 TI - [Instructing families in the treatment of pediculosis]. PMID- 6925798 TI - [Teaching of patients by qualified nurses]. PMID- 6925799 TI - [Instructing mothers in breast feeding in the maternity ward of Beilinson Medical Center]. PMID- 6925800 TI - [Treatment of hemiplegia according to the Bobath method]. PMID- 6925801 TI - [Teaching program for patients treated with ambulatory peritoneal dialysis]. PMID- 6925803 TI - The '2+1' nursing curriculum: the what and why; an evaluation. PMID- 6925804 TI - Foetus in foetu. PMID- 6925805 TI - Nursing and the role of TNAI. PMID- 6925806 TI - SNA: how to make it more meaningful. PMID- 6925802 TI - Hospital interactions: communication by nursing personnel. PMID- 6925807 TI - Coronary care unit. a study in administration. PMID- 6925808 TI - Ophthalmic guidance in eye nursing. PMID- 6925810 TI - Outlook on ageing: happiness of the aged depends mainly on a positive outlook on ageing. PMID- 6925812 TI - Empathy and related factors: the psychiatric nursing context. PMID- 6925809 TI - A nursing care study: congestive heart failure. PMID- 6925811 TI - Tubercular patients: a study. PMID- 6925814 TI - Objective type tests for nurses. PMID- 6925813 TI - Nurses and community health programmes. PMID- 6925815 TI - Patients are people! A medico-social approach. PMID- 6925818 TI - Stars in hospital: the nurses made it better. PMID- 6925822 TI - Nursing types: a guide to the student nurse. PMID- 6925816 TI - Art of observation. 18. Time to celebrate the family. PMID- 6925821 TI - Survival kit for managers. 12. Know your health authority. PMID- 6925819 TI - Emergency: arresting fears at night. PMID- 6925820 TI - Law - 4. A question of liability. PMID- 6925817 TI - To be or not to be a nurse? Children's essay competition. PMID- 6925824 TI - Antenatal clinics. 5. Continuity of care. PMID- 6925823 TI - Pressure sores: a change for the better. PMID- 6925825 TI - Ophthalmic preparations. PMID- 6925826 TI - Careers: psychosexual counselling. PMID- 6925827 TI - New synthetic casts: what nurses need to know. PMID- 6925828 TI - Furthering nursing practice through legislative and political action. PMID- 6925829 TI - Components of musculoskeletal examination. PMID- 6925830 TI - Patient management following Amipaque myelography. PMID- 6925832 TI - [Variant: human being. Interview by Wanda Strzalkowska]. PMID- 6925833 TI - ['i" Must be dotted]. PMID- 6925834 TI - [Success in the profession]. PMID- 6925831 TI - [Season in nutrition]. PMID- 6925835 TI - [Etiopathogenesis of peptic ulcer in the light of current viewpoints]. PMID- 6925837 TI - [Polish Red Cross means generosity]. PMID- 6925836 TI - [Midwife in relation to the pregnant woman]. PMID- 6925838 TI - [Drug resistance of bacteria in infection. 2]. PMID- 6925839 TI - [Abortion]. PMID- 6925840 TI - [Biological rhythms in medicine]. PMID- 6925842 TI - Ophthalmology in office practice. PMID- 6925841 TI - [Statute on nursing]. PMID- 6925843 TI - Ophthalmic anatomy. AB - A brief review of the anatomy of the eye, the eyelid, and the lacrimal system provides reference material for the articles that follow in this issue. Pathologic changes in the normal anatomy that can help the physician diagnose an ophthalmic or systemic problem are highlighted. PMID- 6925844 TI - Ocular history and examination techniques. AB - The author proceeds on the assumption that the majority of ocular diseases can be diagnosed by the primary care physician. The interpretation of common symptoms and guidelines for examination of the eye are provided. PMID- 6925845 TI - Strabismus, amblyopia, and dyslexia. AB - Accurate ocular assessment in the pediatric patient can be a challenge to the primary care physician. Guidelines are suggested for ocular evaluation in children of varying ages. Strabismus, amblyopia, and dyslexia are among the most common ocular problems seen in children; medical, surgical, and educational means to treat these disorders are emphasized. PMID- 6925846 TI - Neuro-ophthalmology. AB - Ocular symptoms may indicate the presence of systemic or neurologic disease rather than simply local eye disease. Patients with such symptoms often present initially to the family physician. This article discusses important aspects of the neuro-ophthalmic examination that can aid the physician in identifying common neuro-ophthalmic disorders. PMID- 6925850 TI - Care of cataracts. AB - Medical management may be beneficial for certain types of cataracts, depending on the visual needs of the patient and concomitant ocular or systemic conditions. Surgical intervention and postoperative visual rehabilitation with the use of glasses or contact lenses has a high success rate, although the patient should be followed closely for complications that can occur months to years after surgery. PMID- 6925847 TI - Corneal and external diseases of the eye. PMID- 6925851 TI - Factors influencing knowledge, attitudes, and compliance of hypertensive patients. AB - Using a factorial design, four aspects of an educational program for 160 hypertensive patients were manipulated: number of meetings, patient responsibility and participation, directiveness of the intervention, and emphasis on negative consequences of uncontrolled hypertension. Validity checks on the manipulations included content analysis of the nurse-patient interaction and interview-based measures of the patient's responsibility, participation, and awareness of dangers. Outcome variables included repeated measures of patient knowledge, assessment by the nurse of patient attainment of identified goals, and reduction of the patient's mean arterial blood pressure. High indirect interventions tended to lead to higher goal attainment, particularly in the psychosocial area. Emphasis on negative consequences tended to promote learning for patients with long standing diagnoses, but to retard learning for recently diagnosed patients. Additional meetings and emphasis on patient responsibility were not helpful alone, but in combination they tended to lead to greater learning. Although as a whole, patients in the program tended to reduce their blood pressures, there were no statistically significant main effects or interaction effects of the educational approach variables on blood pressure reduction. PMID- 6925848 TI - Intraocular inflammatory disorders: uveitis. AB - Emphasis on the association between intraocular inflammatory disorders and systemic disease guides the clinical descriptions of acute and chronic uveitis in this article. Practical information on establishing the diagnosis and treating the condition is provided. PMID- 6925852 TI - Continuing education and the professional orientation of nurses. AB - The relationships among continuing education (CE) of nurses, their professional orientation, and selected background characteristics were examined. It was hypothesized that attitudes toward, and participation in, CE were related to professional orientation and not to background. Data were obtained from 82% of a random sample of 395 currently registered nurses living in a midwestern state. The results of a multiple regression analysis were consistent with the study hypotheses. Attitudes toward CE were predicted best by attitudes toward the professionalization of nursing and by future career intentions. Participation in CE was predicted best by current employment status, formal education beyond the initial nursing program, and independent learning activities. None of the four background variables (age, initial nursing program, parental status, and marital status) was a significant predictor. CE was seen, therefore, as an activity of professionally oriented nurses. PMID- 6925849 TI - Ocular trauma. AB - This article guides the primary care physician in determining whether an injury to the eye requires immediate care, immediate referral, or routine treatment. Prevention of ocular trauma through government regulation and the wearing of protective eye gear is emphasized. PMID- 6925853 TI - Increased child abuse in families with twins. AB - Close spacing of children may be a significant risk factor for subsequent abuse in some families. Twin births are an extreme example of close spacing. Therefore, the authors hypothesized that twin births may predispose to an increased incidence of child abuse. Thirty-eight families with twins were compared with 97 single birth families and matched for birthdate, maternal age, race, and socioeconomic status. Families with twins experienced a significantly higher incidence of child abuse and neglect than did those with single births (p less than .003). A written questionnaire designed to study mothers' feelings and perceptions of support systems showed a significant difference only in greater difficulty in feeding twins as compared with single infants (p less than .001). Mothers of abused children were more likely not to answer the questionnaire at all (p less than .005). Neither mothers of single births nor those of twins felt that health professionals provided adequate education or support following the birth of their infants. PMID- 6925857 TI - [Study of curricular reorganization of the undergraduate course of the Ribeirao Preto School of Nursing - University of Sao Paulo. Committee of Curricular Reconstruction of the Ribeirao Preto School of Nursing - USP]. PMID- 6925854 TI - Multidimensional assessment of psychological problems in children with cancer. AB - The Personality Inventory for Children (PIC) was administered to 88 children 3 to 16 years of age who had cancer. A variety of dimensions of psychological adjustment of these children, who were compared with a sample of nonsick children, was assessed. The PIC indicated that children with cancer exhibited cognitive development-related problems and internalized forms of psychopathology more often than their age- and sex-matched cohorts. In the cancer sample, no differences in problems as a function of diagnoses were observed when controlling for age of the child. No differences related to length of time since diagnosis were observed when controlling for age of the child. About 26% of the children with cancer exhibited PIC profiles indicating problems of such magnitude that professional intervention would be appropriate. PMID- 6925855 TI - New Hampshire nurses learn politics the hard way. PMID- 6925856 TI - Nursing specialties: childbirth educator. PMID- 6925858 TI - [Smoking among instructors and students of schools of nursing]. PMID- 6925860 TI - [The discipline of pediatric nursing: students' evaluation of a new method of teaching]. PMID- 6925859 TI - [Iatrogenic disease: implications for nursing care]. PMID- 6925861 TI - [The noise emitted by equipment used in operating rooms: preliminary study of the physical, physiological and psychological changes in members of the surgical team and in patients]. PMID- 6925862 TI - [Nurse in the national immunization program]. PMID- 6925863 TI - [Nursing: the distribution between having and being]. PMID- 6925865 TI - [Gesture that saves]. PMID- 6925864 TI - [Composition of nursing notes from the viewpoint of the medical team]. PMID- 6925866 TI - [Breast feeding: advantages and disadvantages]. PMID- 6925867 TI - [Breast feeding: a program of orientation and support]. PMID- 6925868 TI - [Role of the nurse in the planning of an operating room]. PMID- 6925869 TI - [Nursing care: tetanus in the newborn infant]. PMID- 6925872 TI - [Nursing and new directions in community health]. PMID- 6925871 TI - [Pulmonary function in smokers and nonsmokers]. PMID- 6925870 TI - [Action on post-parturients with breast engorgement]. PMID- 6925873 TI - [Interhuman transmission of rabies]. PMID- 6925874 TI - [Spanish nursing facing the challenge of "Health for All in the Year 2000"]. PMID- 6925876 TI - [Atelectasis]. PMID- 6925877 TI - [Nursing specialization in intensive care. Experience gained over 4 years of the development of the specialty]. PMID- 6925878 TI - [Exanthematous diseases of infancy]. PMID- 6925875 TI - [Medullary injury. V. Sociopolitical aspect]. PMID- 6925880 TI - [Yesterday and tomorrow of nursing]. PMID- 6925879 TI - [Diets with sodium restriction]. PMID- 6925881 TI - [Of miracles, oneiric medicine and quacks]. PMID- 6925882 TI - [Transcutaneous measurement of arterial pO2 and local perfusion using a modified Clark electrode]. PMID- 6925883 TI - [Cases of intubated children. Our experience and care in the pediatric intensive care unit of San Cecilio Clinical Hospital of Granada]. PMID- 6925885 TI - [Sociology and nursing. Practical applications]. PMID- 6925886 TI - [Diet of the heart patient]. PMID- 6925884 TI - [Variations in arterial pressure in seated or supine posture during 10 minutes of rest]. PMID- 6925889 TI - [Pulmonary tuberculosis. I]. PMID- 6925891 TI - [Nursing care of the oncological patient at the chemotherapy stage]. PMID- 6925890 TI - [Role of the nurse in pain care for the tumor patient]. PMID- 6925892 TI - [Alternative to health education methods, an FM station (education via radio)]. PMID- 6925893 TI - [Nutritional needs. I]. PMID- 6925888 TI - [Report on rats and mice present in our center]. PMID- 6925887 TI - [Public health nursing specialty in the United Kingdom]. PMID- 6925894 TI - [Nursing specialty in psychiatry. Experiences gained over 12 years of development of the specialty]. PMID- 6925895 TI - [Old age is not a disease]. PMID- 6925897 TI - [Echography: new diagnostic method in obstetrics. Basic ideas applied to nursing]. PMID- 6925896 TI - [Tuberculin]. PMID- 6925898 TI - [Dangers of self medication]. PMID- 6925899 TI - [Pulmonary tuberculosis. II]. PMID- 6925901 TI - [Interview with Maricel Manfredi]. PMID- 6925902 TI - [Work on public health in the rural and semi-urban environment]. PMID- 6925903 TI - [Hemotherapy]. PMID- 6925904 TI - [Pneumology]. PMID- 6925905 TI - [Nursing specialties]. PMID- 6925900 TI - [Vaccinations]. PMID- 6925906 TI - [Iatrogenesis and quacks]. PMID- 6925907 TI - [Nutritional needs. II]. PMID- 6925908 TI - [Disaster planning]. PMID- 6925909 TI - [Disaster. The true test]. PMID- 6925910 TI - [When a disaster happens]. PMID- 6925912 TI - [Skin as a factor in contaminating the surgical wound]. PMID- 6925911 TI - [Bacterial protection in surgical practice. Ideas taken from practice]. PMID- 6925913 TI - [Bacterial pollution in the operating room]. PMID- 6925914 TI - Caritas Hospice Society: we listen. PMID- 6925918 TI - Council on Education completes a study of minority representation in nursing education programs in South Carolina. PMID- 6925917 TI - If Florence could see us now! PMID- 6925915 TI - Building a budget. PMID- 6925916 TI - Therapeutic failure in pneumonia caused by a tolerant strain of Staphylococcus aureus. PMID- 6925919 TI - Nursing 2000: social changes--making a world of difference. PMID- 6925920 TI - N.C. nurses visit China health services for a billion people. PMID- 6925921 TI - Primary health care. PMID- 6925922 TI - Minister calls for help from the nursing profession. PMID- 6925923 TI - The role of nursing in primary health care. PMID- 6925924 TI - Benefits of quality assurance to patients. PMID- 6925925 TI - Cardiac arrest - the small hospital and the nurse! PMID- 6925926 TI - Ultrastructure of the rat tracheal epithelium in leukoelastase-induced emphysema. PMID- 6925927 TI - Some acute inflammatory reactions in a strain of Brown-Norway rats which are deficient in kallikrein-kinin system. PMID- 6925928 TI - Physician's perspective on the nuclear age. PMID- 6925929 TI - The nurse and the law. Foreseeing the damage. PMID- 6925930 TI - The food factor and the scientific nurse: hospital malnutrition. PMID- 6925931 TI - Drugs in current use: potassium chloride. PMID- 6925932 TI - Snake bite--a case history. PMID- 6925933 TI - Massive obesity: a nurse's view. PMID- 6925934 TI - An innovation: the psychiatric intensive care unit. PMID- 6925935 TI - Burn nursing. PMID- 6925936 TI - An alternative staffing pattern for domiciliary care: registered nurses and substitute relatives. PMID- 6925938 TI - Post natal support. PMID- 6925937 TI - The last epidemic. PMID- 6925939 TI - Guidelines on tonsillectomy and adenoidectomy in children. PMID- 6925940 TI - The Warrnambool and district base hospital. PMID- 6925941 TI - Post natal support. PMID- 6925942 TI - Homebirth. PMID- 6925943 TI - Vitamin C, use or abuse? PMID- 6925945 TI - I choose, you choose. PMID- 6925946 TI - Changes in systemic oxygen delivery during chest physiotherapy. PMID- 6925944 TI - Keeping the elderly at home. PMID- 6925948 TI - Child birth: an important event for a grandmother midwife. PMID- 6925947 TI - Tabling speech. PMID- 6925949 TI - Some thought on the role of the nurse in combatting child abuse. PMID- 6925950 TI - Necrotising entercolitis--an iatrogenic problem in the intensive care of the sick neonate. PMID- 6925951 TI - Keeping the elderly at home. PMID- 6925952 TI - Do Care: an exercise in community care. PMID- 6925953 TI - A look at the future in domiciliary care. PMID- 6925954 TI - The age of caring: admission to institutional care and day centres. PMID- 6925955 TI - Our young unemployed: their deprivation and their needs. PMID- 6925956 TI - Professionalism through unionism. PMID- 6925958 TI - The aging process: many physiological functions change with age. PMID- 6925957 TI - 'Lady of the lamp' returns. PMID- 6925959 TI - Sporting reminiscence. PMID- 6925960 TI - The kyphotic posture and irritable colon? PMID- 6925961 TI - If it's poison you can't kiss it better. PMID- 6925962 TI - Burn wound sepsis. PMID- 6925964 TI - The modular basis of the new occupational health nursing higher certificate course. PMID- 6925963 TI - Shattered. PMID- 6925965 TI - Anger and violence. PMID- 6925966 TI - Ascorbate (vit C) utilisation in humans when subjected to moderate/heavy physiological stress. PMID- 6925967 TI - Social and organisational problems in a major community emergency. PMID- 6925968 TI - First aid on the road. PMID- 6925969 TI - Nursing care of the patient following radio therapy. PMID- 6925970 TI - Sisters for sale. PMID- 6925971 TI - First aid services in industry. PMID- 6925973 TI - Health hazards of being a student. PMID- 6925975 TI - Simple remedies for complex problems. PMID- 6925972 TI - Health supervision in small industries. PMID- 6925977 TI - Role of the medicine nurse on the psychiatric team. PMID- 6925974 TI - Parotid microsomal Ca2+ transport. Subcellular localization and characterization. AB - Rat parotid gland homogenates were fractionated into mitochondrial, heavy microsomal and light microsomal fractions by differential centrifugation. ATP dependent 45Ca2+ uptake by the subcellular fractions paralleled the distribution of NADPH-cytochrome c reductase, an enzyme associated with the endoplasmic reticulum. The highest rate of Ca2+ uptake was found in the heavy microsomal fraction. Ca2+ uptake by this fraction was dependent on the presence of ATP and was sustained at a linear rate by 5 mM-oxalate. Inhibitors of mitochondrial Ca2+ transport had no effect on the rate of Ca2+ uptake. Na+ and K+ stimulated Ca2+ uptake. At optimal concentrations. Na+ stimulated Ca2+ uptake by 120% and K+ stimulated Ca2+ uptake by 260%. Decreasing the pH from 7.4 to 6.8 had little effect on Ca2+ uptake. The Km for Ca2+ uptake was 3.7 microM free Ca2+ and 0.19 mM-ATP. Vanadate inhibited Ca2+ uptake; 60 microM-vanadate inhibited the rate of Ca2+ accumulation by 50%. It is concluded that the ATP-dependent Ca2+ transport system is located on the endoplasmic reticulum and may play a role in maintaining intracellular levels of free Ca2+ within a narrow range of concentration. PMID- 6925976 TI - Teaching strategies used to promote positive feelings about a clinical site. PMID- 6925978 TI - "Those golden years"? PMID- 6925979 TI - Decrease in the phagocytic activity of peripheral monocytes in patients treated with human interferon-alpha. AB - The influence of daily intramuscular injections of 3 X 10(6) units of interferon alpha (IFN-alpha) on the phagocytic activity of peripheral monocytes was studied in 28 tumor patients. One day after initiation of IFN therapy no major change in the capacity of monocytes to ingest yeast particles was observed. After 1 week, 3 months, 6 months, and 9 months of treatment, monocyte phagocytosis had decreased in the majority of the patients tested. In patients where natural killer (NK) cell activity was measured simultaneously with monocyte phagocytosis, a correlation between the degree of enhancement of NK activity and the degree of decrease in monocyte phagocytosis was observed. PMID- 6925980 TI - Antigens in immune complexes from patients with breast cancer. Identification of autoantigens in immune complexes isolated from breast cancer effusions. AB - Sera and effusion fluids of patients with breast cancer (BC) contain immune complexes (IC). Antigens present in these complexes were isolated as follows: a pool of effusions from patients with BC was fractionated with ammonium sulfate. The proteins precipitating at 40% saturation were further fractionated by filtration through a Sephadex G-200 column. The material recovered in the first peak (molecules larger than monomeric IgG) was brought to pH 3.0 to dissociate the IC, and the mixture was filtered through a column of Sephacryl S-300 at pH 3.0. Proteins smaller than monomeric IgG were collected, radioiodinated, and used as antigens (125Ag) to search for corresponding antibodies in sera of patients with BC (BCS) and of healthy individuals (NHS). 125Ag was reacted with the sera and the immune complexes obtained were precipitated with an antiserum to human Ig and analyzed by SDS-polyacrylamide gel electrophoresis followed by autoradiography. Both NHS and BCS contained antibodies against two antigens; one of these appeared as a strong band of 17KD, the other as a doublet of approximately 25KD. It is concluded that some of the proteins in the IC from patients with BC are auto-antigens. No BC-specific antigens were identified. PMID- 6925981 TI - Divergence in activation by poly I:C of human natural killer and killer cells. PMID- 6925983 TI - A follow-up study on chemoimmunotherapy (5-fluorouracil and BCG) in advanced gastric cancer. AB - Two hundred and seventeen patients with advanced gastric cancer were classified according to the resectability of the tumour into two groups: I, resectable (non radical surgery), 99 patients, and II, non-resectable carcinoma, 118 patients. Within each group patients were randomly assigned to receive 5-fluorouracil (5 FU) + BCG, 5-FU, or no further treatment (surgery only). BCG was given by scarification. A 2-year follow-up is reported. The group of patients with resectable tumours and receiving chemoimmunotherapy had a statistically significant prolongation of survival compared with the 5-FU and surgery only groups. No differences in survival were observed between these treatment modalities in patients with non-resectable tumour. These observations indicate that chemoimmunotherapy may be of benefit for a selected group of patients with gastric cancer. PMID- 6925982 TI - Regional immunotherapy in resectable squamous cell lung carcinoma. Analysis of a randomized study. AB - Patients with resectable squamous cell carcinoma were randomly allocated after surgery to receive either no further treatment (57 patients) or a single intrapleural injection of BCG (61 patients). No significant improvement in survival was observed in patients treated with BCG, even when their disease was staged as N0. There was a slight trend for the recurrence rate to be lower in patients classed as N0, but this was not significant. PMID- 6925984 TI - Inhibition of a mouse hepatoma by the alkylating agent Trenimon linked to immunoglobulins. AB - Trenimon was conjugated in active alkylating form to rabbit anti-mouse H6 hepatoma globulin (AHG) with retention of antibody activity. H6 hepatoma inoculated mice were given various combinations of conjugates, free Trenimon, and unconjugated immunoglobulins in daily injections for 5 days. Linkage of Trenimon to immunoglobulins reduced systemic toxicity of the drug, with comparative retention of its antitumor activity. The antitumor action of Trenimon was potentiated by AHG irrespective of whether the drug was directly linked to AHG or free AHG was administered along with Trenimon linked to normal rabbit globulin (NRG). In vitro, Trenimon bound to AHG was less inhibitory to hepatoma cells than free Trenimon, but more inhibitory than Trenimon-NRG conjugates. There was no significant endocytosis of conjugates by the hepatoma cells. This suggests that unlike free Trenimon, the target molecules of Trenimon-immunoglobulin conjugates are not intracellular DNA but are located on the surface of the hepatoma cells. PMID- 6925985 TI - The immunopathological effects of intracolonic injection of Mycobacterium bovis BCG cell wall emulsions in guinea pigs. PMID- 6925986 TI - Chemical modification of cytosine residues of tRNAVa1 with hydrogen sulfide (nucleosides and nucleotides. XL). PMID- 6925987 TI - "Quality circles in health care: management tool of the '80's". PMID- 6925989 TI - Territoriality in critical care. PMID- 6925990 TI - Developing and implementing orientation to a critical care unit. PMID- 6925991 TI - Clinical evaluation of a new critical care nurse. PMID- 6925992 TI - Using research in practice. What effects do drugs given in critical care areas have on patients' sleep? PMID- 6925993 TI - Legal issues in nursing. Gone are the days when a nurse can legally 'pass the buck' to the physician. . . PMID- 6925994 TI - Team building--a key to success. PMID- 6925988 TI - Factors affecting job satisfaction/dissatisfaction among critical care nurses. PMID- 6925995 TI - Preceptors for critical care areas. PMID- 6925999 TI - [Purpura]. PMID- 6925997 TI - [Work of women]. PMID- 6925996 TI - [Health in the life of adolescents. Some biologic aspects. I. Report. II. Role of public authorities]. PMID- 6925998 TI - [Understanding of the extramural nurse]. PMID- 6926000 TI - [Sensory deprivation in the elderly]. PMID- 6926001 TI - [Watch out! for sudden infant death syndrome]. PMID- 6926002 TI - [Brief illustrated guide to problem solving]. PMID- 6926003 TI - [Variable time-schedule and the working person]. PMID- 6926004 TI - [Point-blank. With open heart]. PMID- 6926005 TI - [Legal aspects. Negligence in the delivery room: a tragic lesson]. PMID- 6926006 TI - Nursing research in obstetrics and gynaecology. PMID- 6926007 TI - The recovery of physical fitness. PMID- 6926008 TI - The implementation of research findings into nursing practice. PMID- 6926009 TI - Disseminating nursing research information in the U.K.: Nursing Research Abstracts from the Index of Nursing Research. PMID- 6926010 TI - Shared perceptives on State Board role. From executive . . . From Board member . . . PMID- 6926011 TI - Questions and answers on the licensure examination. PMID- 6926012 TI - Studying nurses as strategists. PMID- 6926013 TI - Definition of nursing practice. PMID- 6926014 TI - Options for assuring continuing competency. PMID- 6926015 TI - Should State Boards of Nursing accredit nursing education programs? PMID- 6926016 TI - Implementation of the diagnostic assessment program. PMID- 6926017 TI - Assessment in other health professions. PMID- 6926018 TI - Assessment through testing. PMID- 6926019 TI - Politics and the professions. PMID- 6926020 TI - Is health visiting a profession? PMID- 6926021 TI - Tomorrow's health visitor: can she change our attitudes to health? PMID- 6926022 TI - Are you healthy--or lucky? PMID- 6926023 TI - The health visitor--an authority on child rearing, or an agent of social control? PMID- 6926024 TI - Primary health care in the inner city: time for a new approach? PMID- 6926025 TI - Letter from Singapore. PMID- 6926026 TI - The policy implications of a positive approach to health. PMID- 6926027 TI - Specific alteration of post-transcriptional modification of tRNA in tumor cells. PMID- 6926028 TI - Characterization of a rat tRNA gene cluster containing the genes for tRNAAsp, tRNAGly, and tRNAGlu, and pseudogenes. AB - Molecular cloning and sequence analysis of a rat DNA fragment hybridized to purified tRNAAsp revealed that the genes for tRNAAspGAU(C), tRNAGlyGGA(G), and tRNAGluGAG are in a cluster on the rat chromosome. These genes are arranged in this order and are regularly separated by DNA regions of about 450 bp. The cluster is reiterated about 10 times on the haploid DNA and is present exclusively in a 3.3 kb region cleaved by restriction endonuclease EcoRI. Five lambda clones each containing an independent repeating unit were isolated from a rat gene library. The clones revealed that the length of the repeating unit including the 3.3 kb EcoRI fragment was at least 13.5 kb. Nucleotide sequence analysis and in vitro transcription of the 3.3 kb DNA in the isolated lambda clones showed sequence variations among the repeating units and the presence of incomplete genes for tRNAGly and tRNAGlu within the clusters. PMID- 6926029 TI - Crystallographic study of the binding of a trifluoroacetyl dipeptide anilide inhibitor with elastase. PMID- 6926030 TI - [Clinical characteristics of prostatic diseases and nursing assistance. Prostatic cancer]. PMID- 6926031 TI - [Clinical characteristics of prostatic diseases and nursing assistance. Urination dysfunctions caused by neurogenic bladder and bladder neck fibrosis]. PMID- 6926032 TI - [Pre- and post-operative nursing of patients with prostatic diseases]. PMID- 6926033 TI - [Nursing following prostatectomy - pre- and post-operative management]. PMID- 6926034 TI - [Urination and other problems following prostatectomy - nursing of patients having a closed system indwelling catheter]. PMID- 6926035 TI - [Urination care and health instructions at hospital discharge following TUR-P (transurethral prostatectomy]. PMID- 6926038 TI - [Utilization of enterostomy equipments in Japan - with special reference to skin adhesives and barriers]. PMID- 6926036 TI - [Nursing of a patient with prostatic disease associated with involvement of the urinary tract - nursing of an aged patient in the terminal stage of prostatic cancer having ureterostomy]. PMID- 6926037 TI - [Nursing actions to ease the anxiety of a patient with prostatic cancer - a study of a patient disturbed by loss of sexual function]. PMID- 6926039 TI - [Continuous use of nebulizers and their effects in chronic respiratory tract diseases]. PMID- 6926040 TI - [Pathology of the oral cavity and pharynx and the focal points of observation]. PMID- 6926041 TI - [Significance of nursing diagnosis and its methods in oral diseases - nursing standards and their practice in oral cancer]. PMID- 6926042 TI - [Bactericidal effects of Hibitane, Hypal #3, and Osvan on Pseudomonas (P. aeruginosa, P. cepacia and P. malfophilia)]. PMID- 6926043 TI - [Exercise prescription and nursing (2). Use of the medical history card to find the daily activities of the patient]. PMID- 6926046 TI - [Multiple organ involvement in liver cirrhosis]. PMID- 6926044 TI - [Medical electronics for nurses. Safety of the equipment used in medical electronics]. PMID- 6926045 TI - [The diagnostic process (1980)]. PMID- 6926047 TI - [Nursing of patients with liver cirrhosis. Management of hepatic encephalopathy]. PMID- 6926048 TI - [Nursing of patients with liver cirrhosis. Liver cirrhosis and control of alcohol drinking--implementation of health instructions]. PMID- 6926049 TI - [Nursing of patients with liver cirrhosis. Prescription of rest and exercises for patients]. PMID- 6926050 TI - [Nursing standard for patients with liver cirrhosis caused by type B hepatitis virus]. PMID- 6926051 TI - [Pre-operative nursing and risk factors of cirrhotic patients with portal hypertension--with special reference to esophageal varices]. PMID- 6926052 TI - [Nursing of patients with liver cirrhosis: Nursing of patients with advanced ascites]. PMID- 6926053 TI - [Nursing of patients with liver cirrhosis: nursing during hepatic coma]. PMID- 6926054 TI - [Correction of problem drinking by patients with hepatic encephalopathy. Conference]. PMID- 6926055 TI - [Time study in the development of pain at the contact sites with the bedpan and associated biological responses]. PMID- 6926057 TI - [Assistance extended to patients with poor prognosis and their families--a lesson in role playing]. PMID- 6926058 TI - [Training of new personnel in the radiology department--a study on the orientation program for the new personnel]. PMID- 6926056 TI - [Skin temperature and moisture before and after cleansing with a hot towel and their relationship to the environmental conditions]. PMID- 6926062 TI - [Medical electronics for nurses. (IV). Electrocardiograph, sphygmomanometer, and sphygmograph]. PMID- 6926061 TI - [Prescription of exercises and nursing (3). Graphic presentation and quantification of information]. PMID- 6926060 TI - [Significance and methods of nursing diagnosis and nursing technics associated with breast diseases--problems of stasis of the milk during the puerperal period]. PMID- 6926059 TI - [Pathology of the breast and its diagnostic significance]. PMID- 6926063 TI - [Death experience at the death of a beloved person]. PMID- 6926064 TI - [Therapy of bronchopulmonary infections in adults]. PMID- 6926065 TI - [When they ask you: the plasmapheresis procedure]. PMID- 6926067 TI - [Self knowledge as continued education]. PMID- 6926066 TI - [Urinary calculi - what one can do about it]. PMID- 6926068 TI - [Examination anxiety]. PMID- 6926069 TI - [Man: his new clinical image (11). The body and civilization (1)]. PMID- 6926071 TI - [Direction in geriatric nursing in the curriculum of basic nursing]. PMID- 6926070 TI - [Patient classification system at Toranomon Hospital: discussion]. PMID- 6926072 TI - [Clinical instructions to be given to nursing students assigned to a patient with liver cirrhosis. (1)]. PMID- 6926073 TI - [Image of the nurse expressed by nursing students in verses and drawings by association]. PMID- 6926074 TI - [Interviewing technics in medicine]. PMID- 6926075 TI - [Counseling and interviewing technics in nursing]. PMID- 6926077 TI - [Methods for improvement of counseling and interviewing technics]. PMID- 6926076 TI - [Counseling and interviewing technics utilized in the clinical scene]. PMID- 6926079 TI - [Significance and problems associated with introduction of high technology in medicine]. PMID- 6926078 TI - [Linguistic studies in medical settings. Part 1. Human relationships in medicine observed in conversation]. PMID- 6926080 TI - [Introduction of high technology and reorganization of the medical system]. PMID- 6926081 TI - [Sophistication of medical technology and its effects on nursing]. PMID- 6926082 TI - [Nursing actions which cannot be replaced by machines]. PMID- 6926083 TI - [Industrialization of the hospital and the patient]. PMID- 6926084 TI - [Nursing by private attendants and the patients' independence - assignment of nursing students replacing family members: a case study]. PMID- 6926086 TI - [Establishment of a guideline for nursing rotations based on the actual data on nursing personnel]. PMID- 6926087 TI - [Direction in research on nursing administration. Discussion]. PMID- 6926085 TI - [Man: his new clinical image (12). The body and civilization (2)]. PMID- 6926088 TI - [Changing perspective in nursing education]. PMID- 6926089 TI - [Clinical instruction to be given to nursing students assigned to a patient with liver cirrhosis (2)]. PMID- 6926090 TI - [Evaluation of the effects of clinical training in psychiatry. (1)]. PMID- 6926091 TI - The effects of in vitro ageing on the composition of the intracellular free amino acid pool of human diploid fibroblasts. AB - The composition of the free amino acid pool of the human diploid fibroblast cell line, BCL-D1, was analysed by automated ion-exchange chromatography throughout the life-span of the culture. Significant age-related changes, independent of growth effects, were found with six essential amino acids: a decrease in tyrosine, phenylalanine, leucine, isoleucine and valine, and an increase in methionine. The nature of the changes were suggestive of a decline in the operation of the L-system of amino acid transport with in vitro age. However, it is also possible that age-related changes in the proportions of tRNA iso acceptors and/or the availability and accuracy of tRNA synthetases were involved. PMID- 6926093 TI - On your mark. PMID- 6926094 TI - Poverty--the ultimate handicap? PMID- 6926095 TI - A French experience. PMID- 6926092 TI - The Hunter--according to Olsen. A regional report. PMID- 6926096 TI - Career patterns of nurses with post basic qualifications. PMID- 6926097 TI - Positive good seen in failure of U.N. talks on disarmament. PMID- 6926098 TI - Peace is a nurse's business. PMID- 6926101 TI - [Urinary excretion of kallikrein and hypertension. Statistical comparison of normotensive, hypertensive and borderline cases]. PMID- 6926102 TI - Constructing test questions for higher level thinking. PMID- 6926099 TI - Human relations theory and nursing management in the eighties. PMID- 6926100 TI - [In vitro sensitivity of Salmonella strains to commonly used antibiotics and to some drugs which are not yet used in Turkey]. AB - In Anadolu University Medical School, 55 Salmonella strains were isolated between Nov. 26, 1979 to Feb. 28, 1980 Out of these strains 49.1% were resistant to chloramphenicol, 14,5% to ampicillin and trimetoprium + sulphametoxasol, and 3.6% to tobramycine. All strains were sensitive to gentamycine and amikacine. The differences between the three groups; gentamycine, amikacine and tobramycine; ampicillin and trimetoprim + sulphamitaxasol; and chloramphenicol, were statistically significant. PMID- 6926103 TI - A systematic approach to developing a patient education program. PMID- 6926104 TI - Increasing clinical proficiency: a summer clinical course. PMID- 6926106 TI - Committment to a full profession. PMID- 6926105 TI - Teaching nurses to use computers. PMID- 6926108 TI - The role of nursing educator in primary health care. PMID- 6926107 TI - Role of nursing administrators in primary health care. PMID- 6926109 TI - A tribute to the elderly nurses. PMID- 6926110 TI - Modern trends in the care of the elderly. PMID- 6926111 TI - Clinical forum. 7. ENT nursing. PMID- 6926112 TI - Feeding programmes. Spoonful of success. PMID- 6926113 TI - HV - by appointment only. PMID- 6926114 TI - Pacemakers. 2. Miles ahead. PMID- 6926115 TI - Nursing care study. Determined to fight. PMID- 6926116 TI - Employment law. 3. When job security is at stake . . . PMID- 6926118 TI - Mental illness. PMID- 6926117 TI - The biology of ageing. 2. Reduced resistance. PMID- 6926119 TI - Giving up smoking. Treat it as an illness. PMID- 6926121 TI - Nursing care study. Anxious for help. PMID- 6926122 TI - In at the deep end. PMID- 6926120 TI - Disposable aids. 1. A boost to morale. PMID- 6926124 TI - American nurses association vs. the union: who will help nursing the most? PMID- 6926123 TI - Careers: care of the violent. Fight or flight. PMID- 6926125 TI - [Report from the Central Planning Committee conference in Sala]. PMID- 6926126 TI - [Structure - preference - analysis]. PMID- 6926127 TI - [Inservice education in a Fall BU-class - 82 Boras approved school]. PMID- 6926129 TI - [Health care research - to provide better care to patients]. PMID- 6926128 TI - [Effect of social data on patient care planning]. PMID- 6926130 TI - [Research in Karlskrona Central Hospital. Patient information prior to rectoscopic examination]. PMID- 6926131 TI - [Health care development group, an organizational support for health care development]. PMID- 6926132 TI - [MBD, minimal brain dysfunction--not a disease but a latent handicap]. PMID- 6926134 TI - [Families, I love you, or, a good understanding of hygiene]. PMID- 6926133 TI - [Report from the conference organized by SIDA for the evaluation of nursing instructor programs in Zambia]. PMID- 6926135 TI - [Health education in Besancon]. PMID- 6926136 TI - [Conferences]. PMID- 6926137 TI - [Autonomy, is to be gained]. PMID- 6926138 TI - [Psoriasis]. PMID- 6926139 TI - [Status of research in nursing and obstetrical care of the intermediate term program of the WHO/EURO]. PMID- 6926140 TI - [Prostaglandins and kidney function]. PMID- 6926142 TI - [Speech and language disorders in children. Varied pathology requiring early screening]. PMID- 6926141 TI - [Different types of deafness and their repercussion on language]. PMID- 6926143 TI - [Articulation disorders]. PMID- 6926145 TI - [Anatomy and physiology of phonation organs]. PMID- 6926144 TI - [Pathology of the soft palate]. PMID- 6926146 TI - [Cerebral motor disorders and language disorders]. PMID- 6926147 TI - [Voice in children]. PMID- 6926148 TI - [Deglutition and language disorders]. PMID- 6926149 TI - [Oral and written language disorders]. PMID- 6926150 TI - [Acute language disorders. Sylveline's case]. PMID- 6926151 TI - ["Health education" by Home Health Services]. PMID- 6926152 TI - [In Ille-et-Vilaine. . . An experiment in health education organized by D.D.A.S.S. (Departmental Board of Health and Social Action)]. PMID- 6926153 TI - [Normal language development]. PMID- 6926155 TI - [Hospital personnel faced with psychiatric emergencies]. PMID- 6926157 TI - [Psychiatric diseases in a general hospital. A difficult task]. PMID- 6926154 TI - [Women in a crisis at the emergency service]. PMID- 6926156 TI - [Psychiatry ...and emergencies]. PMID- 6926158 TI - [Receptionist's role at the doctor's office and on the telephone]. PMID- 6926159 TI - [Role of the intern in the psychiatric hospitalization ward]. PMID- 6926161 TI - [Social service at the Saint Isabelle]. PMID- 6926162 TI - [Psychiatric diseases in a general hospital. Foreword]. PMID- 6926160 TI - [Psychologists and psychiatrists in a general hospital]. PMID- 6926163 TI - [District psychiatry and psychiatric emergencies]. PMID- 6926164 TI - [Psychiatric emergencies and the police]. PMID- 6926165 TI - [A few days at Saint Isabelle. A psychiatric unit: description and critical evaluation of an experience]. PMID- 6926166 TI - [New psychosociologic and therapeutic approaches. A danger for whom?]. PMID- 6926167 TI - [Substance abuse in the emergency service and in hospital units]. PMID- 6926170 TI - [The importance of dialogue in therapeutics]. PMID- 6926171 TI - [New psychotherapies]. PMID- 6926169 TI - [Psychoanalysis]. PMID- 6926172 TI - [Family therapy]. PMID- 6926173 TI - [Introduction to psychotherapy]. PMID- 6926168 TI - [Ethnopsychiatric observations. Elements of symptomatology and clinical studies]. PMID- 6926174 TI - [Emotional psychotherapy]. PMID- 6926175 TI - [Being a therapist in an open consultation in child psychiatry]. PMID- 6926177 TI - [Visit to a nursing home]. PMID- 6926176 TI - [The psychotic in his body image]. PMID- 6926178 TI - [Classification of psychotherapy]. PMID- 6926179 TI - [Liver physiology and physiopathology]. PMID- 6926180 TI - [Surgical liver pathology in the non-cirrhotic patient]. PMID- 6926182 TI - [Liver trauma]. PMID- 6926181 TI - [Surgery of the liver]. PMID- 6926183 TI - [Technical role of the circulating nurse in hepatic surgery, Principal interventions]. PMID- 6926185 TI - [Chronic gastritis]. PMID- 6926184 TI - [Postoperative monitoring of a patient with right hepatectomy]. PMID- 6926186 TI - [Stomach tumors]. PMID- 6926187 TI - [Value of digestive system endoscopy]. PMID- 6926188 TI - [A case of acute dehydration in a child]. PMID- 6926190 TI - [Current practical management of uncomplicated stomach ulcer]. PMID- 6926189 TI - [To intensify the campaign against tropical diseases: each day adds to our knowledge]. PMID- 6926191 TI - [Current diagnosis and treatment of uncomplicated duodenal ulcer. Proposal for management in the tropical zone]. PMID- 6926193 TI - [Voluntary interruption of pregnancy: not an insignificant act]. PMID- 6926192 TI - [Complications of voluntary interruption of pregnancy]. PMID- 6926194 TI - [Who requests voluntary interruption of pregnancy?]. PMID- 6926195 TI - [Therapeutic abortion]. PMID- 6926198 TI - [The guide book of the Ministry of Health on voluntary interruption of pregnancy and social assistance in cases of pregnancy]. PMID- 6926196 TI - [Management of voluntary interruption of pregnancy by a practicing physician]. PMID- 6926199 TI - [Who consults marriage counselors?]. PMID- 6926197 TI - [Legislation relative to voluntary interruption of pregnancy and physicians]. PMID- 6926201 TI - [Being a psychologist in a maternal child welfare center]. PMID- 6926200 TI - [Spasfon]. PMID- 6926202 TI - [Reception of women for a voluntary interruption of pregnancy]. PMID- 6926203 TI - [Methods of voluntary interruption of pregnancy up till the 12th week of amenorrhea]. PMID- 6926204 TI - [First medical examination of the newborn infant]. PMID- 6926206 TI - [Care of the normal newborn infant in a maternity center. A few rudiments to master]. PMID- 6926207 TI - [Nutrition in the first days]. PMID- 6926208 TI - [Small problems after childbirth]. PMID- 6926205 TI - [Care of the newborn infant after childbirth]. PMID- 6926210 TI - [Role of the nurse in the establishment of mother-child relations]. PMID- 6926209 TI - [The newborn infant: a fragile being]. PMID- 6926211 TI - [Newborn infants at risk of infection: study of a definite case]. PMID- 6926212 TI - [Postnatal visit of the maternal-infant welfare nurse]. PMID- 6926214 TI - [Receiving the newborn infant in the labor room]. PMID- 6926213 TI - [Means of communication of babies: posture, movement and vocalization]. PMID- 6926215 TI - [Nurse anesthetists' preoperative visits]. PMID- 6926216 TI - [Practice in the operating room and basic education]. PMID- 6926217 TI - [Borgenhammar and occupational health services]. PMID- 6926219 TI - [Sor-Trondelag has studied: great need for continued education. Care for the dying and pain treatment highest priority]. PMID- 6926218 TI - [Medical rationalization--and nursing services in somatic hospitals]. PMID- 6926222 TI - [Project-oriented education]. PMID- 6926221 TI - [Guardian in the health system]. PMID- 6926223 TI - [Economic castration of continued education]. PMID- 6926220 TI - [Observations after a congress: mankind's last epidemic]. PMID- 6926224 TI - [Primary nursing care - a new model for nursing practice]. PMID- 6926225 TI - [Shortage in resources - or: a lack in the utilization of resources?]. PMID- 6926227 TI - [FTF's President on assessment of pension provisions value increase: an assessment will interfere with the agreements]. PMID- 6926226 TI - [Nurses are the nearest contact persons]. PMID- 6926228 TI - [Minister of the Treasury on assessment of pension provisions value increase: interests may be answer to long-range possibility]. PMID- 6926229 TI - [Infant prophylaxis in Denmark. II. Health visitors' overall effectiveness better than physicians']. PMID- 6926231 TI - [What does the new technology mean to nurses?]. PMID- 6926230 TI - [Frambu Health Center in Norway - an idea to consider: contribution to families with children suffering from rare diseases]. PMID- 6926232 TI - [Health policy in the light of a strained economy]. PMID- 6926234 TI - [Hospital corridors should not be used as sleeping rooms without exemption]. PMID- 6926233 TI - [Continued overcrowding in Copenhagen in 1982]. PMID- 6926235 TI - [Overcrowding in the Copenhagen hospital system. 3. Corridor occupation is almost discontinued in Bispebjerg. Interview by Kirsten Sorrig]. PMID- 6926236 TI - [Overcrowding in the Copenhagen hospital system. 4. Number of nursing home patients underestimated in the P-80 Hospital Plan. Interview by Kirsten Sorrig]. PMID- 6926237 TI - [Disasters in peace and war times: how are we situated in preparedness?]. PMID- 6926238 TI - [Environmental Administration's comments on Barseback's preparedness: preparedness plans for Barseback are superior plans]. PMID- 6926239 TI - [Civil Defense Administration on legal conditions: nurses are a part of Civil Defense]. PMID- 6926240 TI - [I want to negotiate about everything - also about time regulation. Interview by Pia Kristensen]. PMID- 6926241 TI - [Is severe mental distress not a form of pain?]. PMID- 6926242 TI - [Executive meeting 7-8 September 1982. Clarify main features in claim proposal for 1983 negotiations]. PMID- 6926243 TI - [They prepare for battle over practice places]. PMID- 6926245 TI - [Small pensions have created a desire for additional security]. PMID- 6926246 TI - [Medicineman's work in the Bush. People survive by superstition and unlimited faith. Interview by Pia Kristensen]. PMID- 6926244 TI - [Anesthetic gases and working environment: less contamination with increased control and more education]. PMID- 6926247 TI - [Preparation of children for hospitalization: information for children and parents - inspiration for us]. PMID- 6926248 TI - [Skin care in the elderly incontinent of feces: skin care must be based on recognized needs]. PMID- 6926249 TI - [Anesthesia nurse - where are you going?]. PMID- 6926252 TI - [Questionnaire survey among office nurses: qualifying standards should cover broad functional area]. PMID- 6926251 TI - [Danish Nursing Council holds a multinational course. 24 nurses from Africa will learn to negotiate]. PMID- 6926253 TI - [Nurses in the Nykobing County Hospital in Zealand: poor foresight affects both us and the patients]. PMID- 6926254 TI - [Nursing and special care. We ought to observe whether the mentally deficient have eye diseases. Interview by Kristen Sorrig]. PMID- 6926250 TI - [Public production must support private one]. PMID- 6926255 TI - [Education should be about 4 years]. PMID- 6926256 TI - [Are tax problems the representative's role? Taxation system has rights - citizens none]. PMID- 6926258 TI - [Public employees in protest]. PMID- 6926257 TI - [Nursing college solicits applications]. PMID- 6926259 TI - [Health visitor's role in relation to future parents' expectations about life with the first child]. PMID- 6926261 TI - [Unusual initiative in Roskilde. Summer college for the oldest and most infirm]. PMID- 6926260 TI - [Danish Nursing Council's retired nurses: we want to use our knowledge and experience within the Danish society]. PMID- 6926262 TI - [Nursing has remained a more independent part of the hospital effort. Interview by Kirsten Sorrig]. PMID- 6926263 TI - [We must request an open dialogue with physicians' groups]. PMID- 6926264 TI - [Danish Nursing Council's accountant on nurses' deductions for extramural work: keep complaining in cases where justified deductions are denied]. PMID- 6926265 TI - [Professional nursing perspectives in relation to organizational structure in the hospital system: others' panic does not deprive us of nursing leadership]. PMID- 6926266 TI - [The law's provisions are identical for physicians and nurses]. PMID- 6926267 TI - [Health visitor as consultant for immigrants: we shall point at immigrants' troubles]. PMID- 6926268 TI - [Head lice an increasing problem: work in vain when not all take co responsibility]. PMID- 6926272 TI - [Nursing practice - a challenge for research]. PMID- 6926270 TI - [The sirens wail 3 times--and what then?]. PMID- 6926269 TI - [Interaction training - systematic training in communication skills. Models for therapeutic communication]. PMID- 6926271 TI - [Health policy and health economy. 1. How do we ourselves develop and manage the nursing profession?]. PMID- 6926273 TI - [Prescribing, procuring, distribution and documentation of drugs given: nurses' responsibility in a strongly regulated field]. PMID- 6926275 TI - [Executive meeting 14-15 October: discussion underway on the consequences of government interference]. PMID- 6926276 TI - [Health policy and health economics. 3. Health policy depends upon our use of resources]. PMID- 6926274 TI - [Immigrant women from Turkey have mental problems. Interview by Pia Kristensen]. PMID- 6926278 TI - [One step on the road to better team work]. PMID- 6926277 TI - [29 student nurses work with their first care plan in probation practice: interaction with the patients provided the best results]. PMID- 6926279 TI - [The Central Health Education Committee under the Prevention Council: prefer a broad definition over an established one]. PMID- 6926280 TI - [Nurses on the way back to the bedside]. PMID- 6926281 TI - [Health policy and health economics. 4. People should be in the center]. PMID- 6926282 TI - [We need a wage development parallel to that of private employees. Interview by Pia Kristensen]. PMID- 6926283 TI - [Infant prophylaxis in Denmark. 12. Burdened families' evaluation of preventive activities]. PMID- 6926284 TI - [Mutual utilization of practice time]. PMID- 6926285 TI - [We remain set against second-class wage earners. Interview by Soren Palsbo]. PMID- 6926286 TI - [Infant prophylaxis in Denmark. 13. Care of sick infants in 1981]. PMID- 6926287 TI - [Health policy and health economics. 5. Health system will have a more active role in the community]. PMID- 6926288 TI - [Comments on the article about anesthetic gases research: statement lacks proof for the need to lower threshold limit values]. PMID- 6926290 TI - [Nurses in Augustenborg: fight for the right to evaluate our own working conditions]. PMID- 6926289 TI - [Work in a nursing home: inspiring to proceed from wholeness]. PMID- 6926291 TI - [The majority against assessment of pension provisions]. PMID- 6926292 TI - [The place of scientific theory in basic nursing education. A pilot study]. PMID- 6926293 TI - [Nurse in a nursing home: our aged are not served with our not being here]. PMID- 6926294 TI - [Appeal to nurses: unoccupied positions in the nursing home will be filled now. Interview by Soren Palsbo]. PMID- 6926295 TI - [Overcrowding in Copenhagen. 6. A lot of pressure on nurses in Bispebjerg. Interview by Kirsten Sorrig]. PMID- 6926297 TI - [Spiritual care. 1. Can nurses provide spiritual care?]. PMID- 6926296 TI - [Health policy and health economics. 6. Good health system in spite of economy]. PMID- 6926298 TI - [Problems related to nutrition]. PMID- 6926299 TI - [Report from the Congress for Child Abuse and Neglect, Paris, 7-10 September 1982. Abuse of children living outside the family]. PMID- 6926300 TI - [Child abuse and neglect often make deep impressions. Interview by Pia Kristensen]. PMID- 6926301 TI - [Parents' right to power]. PMID- 6926302 TI - [Spiritual care. 2. What are the spiritual needs?]. PMID- 6926305 TI - [Agreement on pension rate: they decide together on the most severe form of taxation. Interview by Peter Hjorth]. PMID- 6926303 TI - [Child abuse in Denmark]. PMID- 6926304 TI - [Treatment proposal in cases of child abuse]. PMID- 6926306 TI - [We pay in butter but we eat margarine. Interview by Soren Palsbo]. PMID- 6926307 TI - [Nursing should be an academic education. Interview by Inger Rosenkvist]. PMID- 6926309 TI - [Report on health education in Denmark: health responsibility in individuals and in the community]. PMID- 6926310 TI - [Spiritual care. 3. Spiritual care and the nursing process]. PMID- 6926311 TI - [Nurses in Augustenborg: don't want be ordered back to work again]. PMID- 6926312 TI - Growth of cells in culture treated with the soluble component of volcanic ash from Mount St. Helens. AB - Volcanic ash was collected immediately after the eruption of Mount St. Helens on May 18, 1980. This ash was extracted with water. The elemental composition of the extracted portion was determined by atomic absorption spectrometry. The aqueous extract was applied at high concentrations (up to 37.5 micrograms/ml) to non confluent mixed cultures of mouse lung cells. Even after treatment for up to 10 days, cell number was typically unaffected by the ash extract. Cell viability was also unaltered, and no grossly observable changes were noted in the cells by light microscopy. We conclude that the water-soluble portion of the ash we tested does not markedly affect growth of the cells most at risk, those of the lung. PMID- 6926313 TI - A response to: "The Purpose of Continuing Education for Nurses: growth or Big 'Bucks"'? PMID- 6926308 TI - [Expectation turns into uncertainty]. PMID- 6926314 TI - Teacher and student cognitive styles: baccalaureate nursing study. PMID- 6926315 TI - Getting our act together. PMID- 6926316 TI - Spotlight on Virginia's psychiatric/mental health nurses. PMID- 6926317 TI - Nursing process bridges education and practice. PMID- 6926319 TI - The Rubik's cube of psychiatric nursing. PMID- 6926318 TI - Are nursing personnel reinforcing mental illness? PMID- 6926320 TI - [Altogether fewer have the means to pay for shortened worktime themselves. Interview by Inger Lernevall]. PMID- 6926321 TI - [From 6-hour days for everybody to work distribution]. PMID- 6926322 TI - [Distance education as a trial for prospective district nurses]. PMID- 6926323 TI - [Radiotherapy assistants - small and at risk professional group. Activities must broaden]. PMID- 6926324 TI - [Riksdag resolution comes too late. Uncertain whether some of the positions will really be used]. PMID- 6926325 TI - [County Council should accept its responsibility and arrange more education positions. Interview by Kristina Johnson]. PMID- 6926326 TI - [Swedish Association for Salaried Health and Nursing Employees and local government agree on basic education]. PMID- 6926328 TI - [The need for pool employees continues]. PMID- 6926327 TI - [A cry from long-term care: understaffing kills us]. PMID- 6926330 TI - [So far no answer on psychiatric students]. PMID- 6926329 TI - [Relatives gladly help out but not at settled times. Interview by Kristina Johnson]. PMID- 6926332 TI - [Profile: Kent Lundholm. Interview by Jan Thomasson]. PMID- 6926331 TI - [Kerstin takes the abbreviated medical education. Now she compensates it with nursing quota. Interview by Viveka Holmertz]. PMID- 6926333 TI - [Gladys has a lift that raises high]. PMID- 6926334 TI - [Data processing in Uppsala: personnel takes part and chooses system]. PMID- 6926335 TI - [County Council Organization's survey on the personnel situation: continued shortage of operating room assistants and nurses]. PMID- 6926336 TI - [Chief environmental protection representatives coordinate and go to meeting]. PMID- 6926337 TI - [Now is the time to form an organization "Nurses against Nuclear Weapons"]. PMID- 6926338 TI - [Professors' and County Council's recommendations on deteriorating care. Personnel critical about closure of hospital]. PMID- 6926339 TI - [Swedish Student Nurses' Association on labor market: needs of nurses and nurse assistants - convert services to nursing departments]. PMID- 6926340 TI - [The wild hunt for nurses: a mere memory]. PMID- 6926341 TI - [Nurse instructor program in Zambia is an excellent assistance project]. PMID- 6926342 TI - [Katie Eriksson, researcher and Dean in Helsingfors: nursing science is just as important as medical science. Interview by Jan Thomasson]. PMID- 6926345 TI - [Eva works with children in Helsingfors. She has a key role in public health care. Interview by Jan Thomasson]. PMID- 6926344 TI - [Our members' abilities are important in an aggressive health and nursing care policy. Interview by Jan Thomasson]. PMID- 6926348 TI - Professionalism and the empowerment of nursing. PMID- 6926343 TI - [Pediatric nurses: we need child health centers for the children's sake]. PMID- 6926349 TI - The professions, employed professionals, and the professional association. PMID- 6926346 TI - Sulphinpyrazone--induced decrease in renal function: a review of reports with discussion of pathogenesis. PMID- 6926347 TI - [Therapeutic tactics in fetofetal transfusion: report of a case]. PMID- 6926350 TI - Society and nursing: the new professionalism. PMID- 6926351 TI - Conflicting loyalties of nurses working in bureaucratic settings. PMID- 6926352 TI - The new federalism: strategies and consequences for nursing in the 1980s. PMID- 6926353 TI - Models of practice: variable charges for nursing care. PMID- 6926355 TI - From self-help to health: alternative services for gay men and lesbians. PMID- 6926356 TI - Standards of psychiatric and mental health nursing practice. PMID- 6926354 TI - Strategic planning for a system of professional nursing practice. PMID- 6926357 TI - The role and concern of nurses in community health and social welfare. PMID- 6926358 TI - Behavior modification in nursing practice. PMID- 6926359 TI - The relationships between measures of student selection, academic achievement and graduate performance. PMID- 6926360 TI - Graduate education in nursing in the United States in the eighties. PMID- 6926362 TI - First seminar-workshop on graduate education in nursing in the Philippines. Proceedings. PMID- 6926363 TI - Proxemics and the nurse. PMID- 6926361 TI - Graduate education in nursing in the Philippines: a challenge. PMID- 6926364 TI - Serial comparison of normal and high-risk babies in terms of six indicators. PMID- 6926366 TI - RANF national conference: standards for nursing practice. PMID- 6926365 TI - Mothering of deaf and mentally retarded children: a comparison of maternal attitudes, child rearing practices and child behavior. PMID- 6926367 TI - Standards for nursing practice. PMID- 6926368 TI - Home health aides. PMID- 6926369 TI - The nurse and the law. Drug 'reactions'. PMID- 6926370 TI - The food factor and the scientific nurse. Diet and blood pressure. PMID- 6926373 TI - Cost constraints and conflict within hospital settings. PMID- 6926371 TI - Post-partum depression. PMID- 6926372 TI - Practice. 1. Do Maslow concepts contribute--to better patient care? 2. Does a knowledge of psychology help a nurse professionally? PMID- 6926374 TI - The invisible children. PMID- 6926375 TI - Keeping up to date with drugs--how the pharmacist can help. PMID- 6926377 TI - Stretch-compression neuropathy. PMID- 6926376 TI - Ethical issues in nursing and health sciences: emerging issues and conflicts. 2. Direct ethical conflicts for nurses. PMID- 6926378 TI - Preservation of acquired music performance functions with a dominant hemisphere lesion: a case report. AB - This paper presents evidence of preservation of acquired music performance functions in a right-handed man with a large dominant hemisphere lesion. Results of music testing, speech pathology testing, neuropsychological testing and neurological examination are presented, with evidence of intact music skills (melodic perception and an ability to read at sight) being compared with lost skills (auditory processing span of 3 digits forward, and impairment of complex rhythmic tasks). Interpretations are offered in light of contemporary theories suggesting that brain processes for musical memory involve different cerebral systems to those for verbal memory. PMID- 6926380 TI - Evaluation of therapists by patients with epilepsy. AB - Fifty-three patients were asked to nominate the most important person treating their epilepsy and asked to give suggestions for improving treatment. One-third of patients named the neuro-specialist as the prime therapist, although there was considerable dissatisfaction expressed concerning the neuro-specialists' manner of communicating. The majority of suggestions for improving treatment reflected a desire for greater rapport between doctor and patient. More open communication would form the basis for increased patient knowledge of epilepsy and greater opportunity for the doctor to consider the important psycho-social aspects of his patients' condition. PMID- 6926379 TI - Changes in peripheral and central nerve conduction with aging. AB - An electrophysiological study was made of 30 normal subjects aged 20 to 70 years. Routine methods were used to measure peripheral motor and sensory functions of the posterior tibial nerve. This nerve was then stimulated at the ankle and recordings made simultaneously over the thoraco-lumbar spine, cervical spine and central sensory cortex. Peripheral and central potentials were reproducibly recorded at each site in all subjects. Peripheral nerve motor and sensory potential amplitudes fell significantly with age, as did the amplitude of the thoraco-lumbar potential. Cervical and central potential amplitudes did not change significantly with age. The peak latencies of thoraco-lumbar, cervical and central potentials all showed a significant increase with age. In addition, when 'central conduction time' was calculated by subtracting thoraco-lumbar or cervical latency from the latency of the cortical potential, a significant prolongation with increasing age was still seen, especially in more rostral pathways. PMID- 6926383 TI - Carotid endarterectomy at Royal Brisbane Hospital and Princess Alexandra Hospital, Brisbane. AB - A retrospective study was made of carotid endarterectomies performed at Royal Brisbane and Princess Alexandra Public Hospitals, the 2 major teaching hospitals in Brisbane, between 1st July 1973 and 30th June 1978. The case histories of the patients undergoing the procedure during the period were studied and the immediate mortality and morbidity associated with the procedure were determined. Records of 38 operations at Royal Brisbane Hospital were found. From these operations there were 3 deaths and 1 completed stroke, a major complication rate of 11%. From 83 operations at Princess Alexandra Hospital there was 1 death and 3 completed strokes, a major complication rate of 5%. Significant delays were noted from the time of referral to the hospitals to the time when endarterectomy was performed. PMID- 6926384 TI - Retention of urine and sacral paraesthesia in anogenital herpes simplex infection. AB - Two definite and 2 probable cases of anogenital herpes simplex and sacral radiculitis are described. Symptoms were typical and consisted of paraesthesia and neuralgic pain in the perineum and legs, urinary retention and constipation occurring within several days to a week after an anogenital herpetic eruption. However, at presentation only 1 case had an obvious history of anogenital herpes simplex. Neurological signs were not striking and consisted of a reduced appreciation of light touch and pin prick over the sacral dermatomes and in 2 cases reduced anal sphincter tone. CSF examination in 3 patients showed a lymphocytosis. Bladder catheterisation was required for up to 2 weeks in 2 patients. The paraesthesia persisted for weeks to months. It should be more widely recognised that anogenital herpes simplex, with sacral radiculitis, is probably the commonest cause of acute retention of urine in young sexually active people. PMID- 6926381 TI - How worthwhile is plasma primidone level measurement? AB - Simultaneous steady-state plasma levels of primidone and phenobarbitone were studied in 43 patients receiving primidone therapy. Primidone and phenobarbitone levels in the individual appeared to be linearly related but steady-state plasma phenobarbitone levels correlated better with primidone dose than did steady-state plasma levels of primidone itself. This pattern of correlation is probably due to primidone being more rapidly eliminated than the phenobarbitone that is derived from it. Steady-state plasma primidone levels showed more inter-dosage fluctuation than steady-state plasma phenobarbitone levels in the same patients. In the subjects studied age, sex, and concurrent anticonvulsant therapy did not alter the relation between plasma levels of primidone or phenobarbitone and primidone dose. The study suggested that knowledge of steady-state plasma primidone levels adds little to knowledge of plasma phenobarbitone levels in guiding the therapy of epilepsy with primidone. PMID- 6926382 TI - Stroke syndromes in young people. PMID- 6926385 TI - Optic nerve decompression in benign intracranial hypertension. AB - Fourteen patients with benign intracranial hypertension who failed to respond to medical treatment, were treated with optic nerve decompression to prevent the sequelae of chronic unrelieved papilloedema. The mechanism by which optic nerve decompression protects the optic nerve is uncertain. These patients were reviewed to evaluate the efficacy of the procedure in the treatment of benign intracranial hypertension and to assess its mechanism of action. Preoperatively all patients had papilloedema, 11 patients had visual obscurations and 6 patients had evidence of visual failure. Postoperatively, visual obscurations and papilloedema resolved in all patients, and 5 of 6 patients had no further deterioration of visual function. Six patients had symptoms of raised intracranial pressure preoperatively and in 3 the symptoms resolved after surgery. Three patients had unilateral optic nerve decompression and papilloedema resolved in both eyes. In 1 patient intracranial pressure monitoring revealed raised pressure preoperatively with no significant change in the first 24 hours after surgery. We conclude that optic nerve decompression is effective in the treatment of benign intracranial hypertension, has its effect locally, and in some patients may lower the intracranial pressure. PMID- 6926386 TI - Familial occurrence of meningioma: a case report. AB - A father and daughter were each found to have an olfactory groove meningioma. No members of the family were found to have neurofibromatosis. There have been 4 previous reports of meningiomas occurring in families, and the present report adds support to the hypothesis that meningioma can be a heredofamilial disorder. PMID- 6926387 TI - Senile Parkinsonism and dopa pharmacokinetics. AB - Senile Parkinsonism can be clinically differentiated from idiopathic Parkinson's disease in younger age groups. It has a slower clinical course, an altered therapeutic response and a more widespread neuropathology. The drug of choice for senile Parkinsonism is levodopa given in low starting daily doses of 100mg, with low increments of 100mg every 4 to 7 days and low maintenance doses of 0.5 to 2.5g daily. Increased absorption of a given dose of levodopa in the elderly explains in part the lower dosage requirements. Combined therapy with a peripheral decarboxylase inhibitor is usually unnecessary in the elderly and carries a higher risk of neuropsychiatric toxicity. The use of a peripheral decarboxylase inhibitor should be reserved for those few elderly patients with significant gastrointestinal side effects and for those who respond poorly to levodopa alone. Anticholinergic agents are in general contraindicated in the elderly, either used alone or in combination with levodopa. PMID- 6926390 TI - Hypotensive central spinal cord infarction: a clinicopathological study of 3 cases of aortic disease. AB - Neuropathological studies of 3 cases of aortic disease, complicated by severe prolonged hypotension, revealed a spectrum of central spinal cord infarction not corresponding to a specific arterial territory. The findings support the concept that the central grey matter of the caudal spinal cord is most vulnerable to oligaemic hypoxia. Variation in the longitudinal distribution of ischaemic damage in the individual case depends primarily on the anatomical pattern of the spinal arterial net and on the nature and distribution of the vascular pathology. PMID- 6926389 TI - Disordered muscle tone and movement. AB - The author's interest in the motor system is traced over a period of 30 years. Early studies on the cat pyramidal tract proved to be of relevance to later work on the control of muscle tone by brain stem and cortical mechanisms. Application of physiological methods disclosed fundamental differences between the increased tone of Parkinson's disease, spasticity and decerebrate rigidity. These differences depend upon the extent to which dynamic and static stretch reflexes are released, and whether the control effects of flexor reflex afferents remain under the control of the brain stem (as in Parkinson's disease), are released (as in spasticity) or even reversed (as in decerebrate rigidity). PMID- 6926388 TI - Assessment of disability in multiple sclerosis a new approach to epidemiological study. AB - The Kurtzke system and overall disability scales (KS) for multiple sclerosis were adapted to questionnaire form (QKS). A qualified nurse recorded Kurtzke ratings, by QKS, from 36 multiple sclerosis patients and 11 healthy controls. These scores were compared with ratings obtained by a doctor with neurological training using the conventional history/examination technique. The results obtained by these 2 methods were closely comparable. The use of a questionnaire appears to be a valid and accurate approach to the determination of disability in multiple sclerosis and may be of particular value in epidemiology and therapeutic trials in this condition. PMID- 6926391 TI - A comparison of Australian caucasian and aboriginal brain weights. AB - The weights of normal brains obtained at autopsy from Royal Perth Hospital and the Perth City Coroner's Department during the last decade were reviewed. The analysis involved 728 Caucasian and 63 Aboriginal brains. The ages ranged from 21 to 90 years, but the Aboriginal group were generally younger than the Caucasian. All brains were examined in detail by the Neuropathology Department, Royal Perth Hospital. Brains with any significant macroscopic or microscopic abnormality were excluded from the analysis. Statistical comparisons between the brain weights of the Caucasians and Aboriginal subpopulations show that Aboriginals had smaller brains than Caucasians. Even after correcting for body height, Caucasian brain weights were significantly heavier than Aboriginal brain weights. Results also showed that men had significantly higher mean brain weights than women of the same age. There was a tendency for the mean brain weight of both men and women to decrease in later life, particularly in the eighth and ninth decades. Ho et al. (1980) showed in their analysis of 1261 brains in the USA, that brain weight decreases from white males to black males to white females to black females. The tendency in both this and the present investigation for the non-Caucasians to have smaller brains than the Caucasians warrants further study. PMID- 6926392 TI - Bilateral optic nerve hypoplasia. AB - In the past 10 years, 15 children with bilateral optic nerve hypoplasia have been studied at the Royal Alexandra Hospital for Children. There were 5 boys and 10 girls. Nine were first-born and they presented at a mean age of 5 months (range: 4 days to 25 months). Five presented with suspected blindness and 7 with abnormal eye movements (nystagmus or less commonly squint). The other 3 presented because of fits or developmental delay. Eight showed evidence of neural damage- microcephaly, seizures and/or abnormalities of tone. Four appeared to be of normal or near normal intelligence, 6 were mildly retarded and 5 severely so. Two patients had already died, one suddenly. Six of the 7 cases investigated in detail had evidence of hypothalamic pituitary dysfunction. Another one had a minimal hypothalamic abnormality. Four were severely growth retarded and 2 were receiving growth hormone replacement. Two males had micropenis and a girl had precocious puberty with partial diabetes insipidus. Neuroradiological investigations showed an absent septum pellucidum in only 5 cases. Five patients had other major CNS malformations. Five patients had normal CT scans; 3 of these 5 appeared of normal intelligence and all 5 had normal neurological examinations. Bilateral optic nerve hypoplasia is frequently associated with serious brain and endocrine abnormalities. PMID- 6926393 TI - Acetylcholine receptor antibodies in the diagnosis and management of myasthenia gravis. AB - The relationship of acetylcholine receptor (AchR) antibodies to disease activity in myasthenia gravis (MG) is controversial. Some authors claim a direct correlation with disease activity and treatment, in particular plasmapheresis therapy, whereas others have commented on the poor overall correlation of antibody levels with clinical state. Antibody levels were examined in a population of MG patients and correlated with disease activity and response to treatment. Antibodies to skeletal muscle AchR were found in most patients with generalised MG (24/25) and in about half of the patients with purely ocular MG (6/10) and in neither of 2 patients with congenital MG. There was scant correlation with disease activity or response to treatment. It is concluded that the assay is more useful for diagnosis than for management of MG. PMID- 6926394 TI - Serum-induced demyelination: an electrophysiological and histological study. AB - Serum from rabbits with EAN in the acute phase of the disease has been injected into rat sciatic nerve, and compared to control rabbit serum and serum from patients with demyelinating neuropathy and to normal human control serum. Electrophysiological studies were performed on all rat sciatic nerves so injected, and the nerve was then removed and examined histologically. Control rabbit and human serum and neuropathic human serum, when injected in a 20 microL quantity through a 30 gauge needle, did not produce significant electrophysiological abnormalities. EAN serum, however, produced significant dispersion of the muscle action potential and conduction block. All serum produced some histological evidence of demyelination but that seen with EAN serum was quite profound compared to all other sera. It is concluded that humoral factors are present within animals with EAN which has potent demyelinating potential. We were not able to demonstrate the same effect from patients with demyelinating neuropathy in this test system. PMID- 6926395 TI - Compression of the tibial nerve by the tendinous arch of origin of the soleus muscle. AB - Details of 5 cases of surgically confirmed entrapment of the tibial nerve in the popliteal fossa are presented. In 4 cases the nerve was compressed beneath the tendinous arch of the origin of the soleus muscle. In 1 of these cases, thrombosis of a tributary of the popliteal vein with oedema of structures in the popliteal fossa and secondary compression of the nerve was found. In the fifth case the popliteal vein was compressed by the soleus arch with secondary compression of the nerve. The clinical presentation in these cases was characterised by severe pain and tenderness in the popliteal fossa, aggravated by active and passive dorsiflexion of the foot, inability to weight bear, and numbness and pain in the sole of the foot and heel. In each case, surgical exploration and division of the soleus arch led to prompt relief of symptoms. PMID- 6926396 TI - Hypokalaemic periodic paralysis unresponsive to acetazolamide. AB - The cases of a 14-year-old farm labourer is presented as a further example of nonacetazolamide responsive hypokalaemic periodic paralysis. The family history was negative, the clinical picture classical, with prompt reversal of symptoms after the use of potassium salts. However, the administration of acetazolamide led to precipitation of an attack within a few days. The use of triamterene 100mg daily resulted in complete cessation of the attacks for the last 12 months with the maintenance of normal serum potassium levels without the use of supplementary potassium. PMID- 6926398 TI - [New discovery in learning by the student nurse]. PMID- 6926399 TI - [Some thoughts after reading the nurse's daily routine in taking care of the patient]. PMID- 6926397 TI - A case of cortical deafness. AB - The presentation of cortical deafness, associated with mild dysphasia due to bilateral temporo-parietal infarction in a 70-year-old man, is described. Partial return of hearing occurred and associated with this a more complex cortical hearing disorder was seen with elements of both decreased auditory acuity and auditory agnosia. After 1 year a mild hearing loss persisted with difficulty in speech discrimination and an inability to recognise music. Bilateral temporo parietal infarction was confirmed by CT scan. The cortical auditory evoked responses were initially absent despite intact brain stem auditory evoked responses. After a year, the cortical evoked responses had returned. PMID- 6926400 TI - [What it should be--nursing and nursing education]. PMID- 6926402 TI - [At the conclusion of my scholarship studies]. PMID- 6926401 TI - [Thoughts after studying Florence Nightingale]. PMID- 6926403 TI - [Joining JCNA scholarship]. PMID- 6926404 TI - [Relationship between the nurse and her patients in the nursing process]. PMID- 6926405 TI - [Daily routine in taking care of the patient]. PMID- 6926407 TI - [Care of patients in continuous extension or subject to decubitus ulcers]. PMID- 6926406 TI - Mouse kallikrein arginyl-esteropeptidase genes: analysis of cloned cDNAs suggests rapid functional divergence from a common ancestral sequence. AB - A previously-cloned cDNA coding for a member of the kallikrein arginyl esteropeptidase group of serine proteases, (pMK-1), was used as a hybridization probe to identify a second partial cDNA clone (pMK-2) from mouse submaxillary gland. pMK-2 shares more than a 98% nucleotide sequence homology with pMK-1; the 3' untranslated regions are identical and there are only two predicted amino acid changes over the C-terminal 66 amino acids. The site of one change is implicated in determining substrate specificity, while the other may affect the catalytic mechanism. Thus despite the marked similarity of pMK-1 and pMK-2, the differences probably give rise to functionally distinct enzymes and are not simply polymorphic alleles. PMID- 6926408 TI - [Nutritional deficiencies observed in infants in France]. PMID- 6926409 TI - [Reality and need for school ergonomics]. PMID- 6926410 TI - Support groups for nursing students in psychiatric rotation. PMID- 6926411 TI - Concepts of stress for nursing. PMID- 6926413 TI - Nursing care of the mentally retarded: communication issues. PMID- 6926412 TI - Group reminiscing therapy with elderly clients. PMID- 6926414 TI - Interventions with disorganized parents of disturbed children. PMID- 6926416 TI - Marital stress in the early years. PMID- 6926415 TI - Sexual knowledge and spouse abuse: a cultural phenomenon. PMID- 6926417 TI - NHS reorganization and health visiting priorities. PMID- 6926418 TI - Do broken marriages affect children? PMID- 6926419 TI - The arrival of a sibling. PMID- 6926421 TI - Identification and management of psychosocial problems by health visitors. PMID- 6926423 TI - Know your organizations: COPE--a way of working with family groups. PMID- 6926422 TI - A private health visiting service. PMID- 6926420 TI - Recent changes in British family life. PMID- 6926424 TI - Know your organizations: the Brook Advisory Centres. PMID- 6926426 TI - Know your organizations: British Pregnancy Advisory Service. PMID- 6926425 TI - Know your organizations: the Birth Control Trust. PMID- 6926429 TI - Homosexuality and the medical model. PMID- 6926427 TI - Anorexia nervosa: distorted body image. PMID- 6926428 TI - Self-care/health maintenance and contraceptive use, information needs, and knowledge of a selected group of university women. PMID- 6926430 TI - Teaching prenatal nutrition in an outpatient clinic: a change project. PMID- 6926433 TI - A reference for clinicians: discomforts of pregnancy. PMID- 6926431 TI - Selection factors involved in the choice of childbirth method. PMID- 6926432 TI - Co-parenting. PMID- 6926434 TI - A reference for clinicians: recommendations to parents. PMID- 6926435 TI - [Myocardial energy metabolism in congestive and hypertrophic states of cardiomyopathy in hamsters with elastase-induced emphysema]. PMID- 6926438 TI - [Current status and an overview of continued nursing. 4]. PMID- 6926437 TI - [My personal history in nursing and my nursing activities--learning the essence of nursing after 20 years]. PMID- 6926439 TI - [Systematic nursing--a nursing process to be used in the clinical scene]. PMID- 6926436 TI - [Symposium: nursing and information science]. PMID- 6926440 TI - [Statistical file: on the graduates of schools of nursing and practical nursing and their employment]. PMID- 6926441 TI - [Learning from the lives of the elders]. PMID- 6926444 TI - [Positive response in nursing actions]. PMID- 6926442 TI - [In search of the scenes of learning and self-development]. PMID- 6926443 TI - [Reflection on my professional activities as a nurse]. PMID- 6926445 TI - [Evaluation of various factors in the discovery of breast cancer]. PMID- 6926446 TI - [Happy mothers and babies: a report from the clinical practice of neonatology]. PMID- 6926447 TI - [Topics in medicine: infants with low birth weight]. PMID- 6926448 TI - [Topics in medicine: phenoxy herbicides and sarcoma]. PMID- 6926449 TI - [Medical topics: myocardial scanning]. PMID- 6926451 TI - [Systematic nursing: a nursing process to be used in clinical nursing]. PMID- 6926450 TI - [Statistical file: ages of students entering schools of public health nursing]. PMID- 6926452 TI - [The current status and an overview of continuity in nursing. 5]. PMID- 6926453 TI - [Nursing research--notes on its development and current status a special speech delivered by Virginia Henderson]. PMID- 6926455 TI - [Mental strength needed in illness, a desire of nursing personnel]. PMID- 6926454 TI - [Nature of the mental process in accepting assistance]. PMID- 6926456 TI - [Assistance without being noticed]. PMID- 6926457 TI - [Reflection by the nursing profession on the pain of patients being cared for]. PMID- 6926458 TI - [Happy mothers and babies: a report from clinical neonatology]. PMID- 6926459 TI - [Profile: Ms. Yuri Iwamoto who conducts a group study on the problems of housing and health]. PMID- 6926460 TI - [Topics in medicine: sex hormone binding globulin]. PMID- 6926461 TI - [Topics in medicine: diseases in homosexual men]. PMID- 6926462 TI - The effects of gentle human touch on mechanically ventilated very-short-gestation infants. PMID- 6926464 TI - Staphylococcal infections among newborn babies in two towns in north Norway. AB - 1137 newborn infants in the towns of Harstad and Tromso were examined for Staphylococcus aureus. The children were followed for two months after birth, and 10% showed signs of infection. The first symptom occurred on the average on the ninth day of life, while the average stay in the maternity ward was six days. 85% of those being regarded on clinical grounds as infected with S aureus showed growth of this bacterium on cultivation of the specimens taken. Over 80% of the strains were resistant to penicillin G/V and approximately 11% resistant to fucidic acid. Resistance to other antibiotics was not found to present any problem. A survey of staphylococcal infections among the newborn should include both the stay in the maternity ward and the first week at home. PMID- 6926466 TI - The development of a family competence instrument related to health. PMID- 6926465 TI - Educational preparation for nursing--1981. PMID- 6926463 TI - Effect of skeletal alkaline phosphatase inhibitors on bone cell proliferation in vitro. AB - Chicken skeletal alkaline phosphatase is subject to competitive inhibitions by vanadate (Ki = 0.38 mM in carbonate, Ki = 0.08 mM in Tris, both at pH 7.4) and phenylphosphonate (Ki = 15 mM in carbonate, Ki = 1.3 mM in Tris, both at pH 7.4), and uncompetitive inhibition by levamisole (Ki = 0.08 mM in carbonate, Ki = 0.10 mM in Tris, both at pH 7.4). The competitive inhibitors were more effective in Tris buffer because nonreactive ternary complexes were formed between alkaline phosphatase, the inhibitor and Tris. The effects of vanadate, phenylphosphonate and levamisole on the proliferation of embryonic chick calvarial cells in vitro were biphasic. Low doses of each agent stimulated 3H-thymidine incorporation into TCA-insoluble material; higher doses were inhibitory. Neither effect could be attributed to inhibition of alkaline phosphatase activity (e.g. 20 microM vanadate should inhibit alkaline phosphatase by 3% but stimulated cell proliferation by 187%; 50 microM vanadate should inhibit alkaline phosphatase by 7% but inhibited 3H-thymidine incorporation by 90%). None of the alkaline phosphatase inhibitors tested affected the cellular concentration of the enzyme during the 24-hour incubation. These studies indicate that alkaline phosphatase inhibitors can have nonspecific effects on bone cells in culture, and that for cells in the osteoblast cell line, an inhibition of alkaline phosphatase activity is not consistently related to a decrease in cell proliferation. PMID- 6926468 TI - A report on faculty practice: promoting health in a children's day centre. PMID- 6926467 TI - The significance of academic preparation. PMID- 6926469 TI - [Promoting family health in a pediatric hospital setting]. PMID- 6926470 TI - Culture and illness: parents' perceptions of their child's long term illness. PMID- 6926471 TI - How to eat a whale - things never told about grant writing in graduate school. PMID- 6926473 TI - [Care of the pregnant woman]. PMID- 6926474 TI - [Care in the period of early infancy]. PMID- 6926472 TI - [Myocardial infarct and nutrition]. PMID- 6926475 TI - [Preparedness for the evacuation of patients and others under care]. PMID- 6926476 TI - [Search for information]. PMID- 6926477 TI - [Prenatal diagnosis of genetic diseases]. PMID- 6926478 TI - [Working conditions in the community]. PMID- 6926479 TI - [Acute laryngitis]. PMID- 6926480 TI - [Preparation of the patient for an operation]. PMID- 6926481 TI - [I am in favor of team care]. PMID- 6926484 TI - [Pregnancy and twin birth]. PMID- 6926482 TI - [Education of personnel for basic health care in Nigeria]. PMID- 6926485 TI - [Midwife and the community; how to achieve the profession]. PMID- 6926483 TI - [Bacteria and drug resistance]. PMID- 6926488 TI - [Contacts]. PMID- 6926486 TI - [Typology of personality]. PMID- 6926487 TI - [Personality and diseases of the respiratory system]. PMID- 6926490 TI - [Tasks and importance of toxicology in the contemporary world]. PMID- 6926489 TI - [Evacuation of patients]. PMID- 6926491 TI - [Culture therapy]. PMID- 6926492 TI - [Administrative nurse]. PMID- 6926493 TI - [Rehabilitation through scouting]. PMID- 6926496 TI - [Return to a good concept]. PMID- 6926494 TI - [Erosion of the vaginal portion of the uterus]. PMID- 6926497 TI - [All about the community midwife]. PMID- 6926495 TI - [Mechanisms altering the resistance of bacteria to antibiotics. 4]. PMID- 6926498 TI - [Glucose solutions]. PMID- 6926499 TI - [Gift or bribe]. PMID- 6926500 TI - [Creativity in teaching of expressive functions. 1. Certain factors can prevent us from carrying out psychological care]. PMID- 6926501 TI - [Recommended standards for hospital food]. PMID- 6926503 TI - [Admission requirements which do not ensure the necessary stability]. PMID- 6926502 TI - [Do nurses desire more levels?]. PMID- 6926504 TI - [Congress showdown on 1981 agreement. If there is a victory is that a reason to fear new victories?]. PMID- 6926505 TI - [Discussion on expansion of educational capacity: a compromise and not an about face]. PMID- 6926506 TI - [Nurses' functional domain in a group of elderly]. PMID- 6926508 TI - [Health policy and health economics. 2. Expectations about continued growth cannot be satisfied]. PMID- 6926507 TI - [Attitude survey concerning personnel uniforms in hospitals: desire for fewer synthetic fibers also concerns work noise]. PMID- 6926509 TI - [WHO's Medium Term Program: 216 nurses report on project at Odense Hospital]. PMID- 6926510 TI - [22 African nurses on a visit to learn negotiating: we need a lot of practice and moral support]. PMID- 6926511 TI - The ratification of the Convention on Psychotropic Substances 1971 and its transposition into national legislation in the Federal Republic of Germany. AB - The Single Convention on Narcotic Drugs, 1961, as amended by the 1972 Protocol Amending the Single Convention on Narcotic Drugs, 1961, and the Convention on Psychotropic Substances 1971 have been implemented in the Federal Republic of Germany as follows: (a) No distinction is made between narcotic drugs and psychotropic substances; all substances which are controlled and non-exempted preparations containing such substances fall under the legal designation of "narcotic drugs"; (b) The same control measures as for narcotic drugs apply to all substances in Schedules II, III and IV of the 1971 Convention, i.e. control of manufacture, trade, import and distribution; (c) Under the new Narcotics Act of the Federal Republic of Germany, which entered into force on 1 January 1982, preparations containing substances listed in Schedules II and III of the 1971 Convention are subject to the same full control measures, including mandatory special prescriptions, with the exception of approximately 50 preparations from substances in Schedule III of the 1971 Convention. These 50 preparations are also subject to import, export and transit controls under the Narcotics Act; (d) The approximately 50 preparations containing substances in Schedule III of the 1971 Convention, as well as all preparations containing substances in Schedule IV of this Convention (about 340), are treated as "exempted preparations" under the Narcotics Act. These preparations, however, may only be dispensed under medical prescription which is in conformity with the provisions of article 9, paragraphs 1 and 2 of the 1971 Convention; (e) Within the meaning of the Narcotics Act, the term "exempted preparations" denotes that no mandatory special prescriptions are required for these preparations but only the normal medical prescriptions. A number of regulations of the Narcotics Act apply to these exempted preparations, including: (i) Licence of manufacture; (ii) Records of dispensing of exempted preparations by the manufacturer to the first acquirer; (iii) Import, export and transit regulations for the exempted preparations containing substances listed in Schedule III (Schedule III B in the Narcotics Act); (iv) Export bans for countries which have prohibited import. PMID- 6926513 TI - Production characteristics of Papaver somniferum L. cultivars of different origin and vegetation cycles. AB - Poppy cultivars of different origin were investigated in long-term experiments during the period 1976-1980. The production ability of plants was established with both spring and autumn sowing, using different plant spacing (20 cm X 20 cm and 50 cm X 20 cm). All important poppy-growing areas within northern and southern Europe were represented by the cultivars brought under investigation ("P 360", "Ankara", "Botosani", "Kompolti-M", "Kek Duna", "Modran", "KM-Ihar" and "Reading"). The extension of the vegetation cycle by autumn sowing and wintering had a generally favourable effect on dry matter and alkaloid production, resulting in a fivefold increase in production. In spite of high production ability, the wintering of the cold-sensitive cultivars, known as spring types, was uncertain. The shortening of the vegetation cycle (spring sowing) seemed to be unfavourable for the production of both spring and autumn cultivars. However, that disadvantage was compensated to some extent by spring cultivars having relatively lower sensitivity and higher alkaloid production levels. The weight of individual plants was much higher when cultivated in large areas. However, a higher yield could be obtained with 20cm X 20cm spacing because more plants could be harvested per square metre. On the basis of production analyses, a negative correlation was established between the total capsule mass (i.e. capsule plus seed) and the ratio of the drug-forming part. In the case of alkaloid production, a positive correlation was established between the accumulation of codeine and the intensification of over-all alkaloid formation. PMID- 6926514 TI - Misuse of psychotropic substances: outline and recommendations of a conference held in London in March 1980. AB - A conference was held in London in March 1980 on the use and misuse of psychotropic substances. The conference noted that there was a preponderance of medical practitioners who prescribed psychotropic substances. The topics covered ranged from the extent of use of psychotropic substances to the effects of their use in producing different types of morbidity. Consideration was given to controls of psychotropic substances, including steps to reduce their misuse without restricting their legitimate use. PMID- 6926512 TI - Spot tests for cannabis materials. AB - Sensitive and specific spot tests are described for the identification of cannabis materials. These spot tests are economical since they utilize minimal amounts of cannabis derivatives and chromogenic reagents. They yield satisfactory results when applied to the cannabis materials and are sensitive at less than 10 micrograms/ml. The described spot reactions are simple, highly reliable and reproducible. PMID- 6926515 TI - [Biological characteristics of kininogenesis in the normal amniotic fluid]. PMID- 6926520 TI - [Proposal for a wage policy program. Controversial section on wage differential]. PMID- 6926517 TI - [Profile of the nurse who studies community health]. PMID- 6926516 TI - [The occupational health nurse]. PMID- 6926519 TI - ["Private investigation"]. PMID- 6926518 TI - [Clinical neuropsychology]. PMID- 6926521 TI - [SHSTF's voice in the planning committee]. PMID- 6926522 TI - [David wants to ration alcohol. Interview by Erling Forsman]. PMID- 6926523 TI - [Louise, Swedish nurse anesthetist in Lebanon: I never forget that horrors happen. Interview by Jorgen Ulvsgard and Eva-Li Johansson]. PMID- 6926524 TI - [They call us brave bulls . . .. Interview by Viveka Holmertz]. PMID- 6926525 TI - [Catastrophic situation in responsibility committee--money and service are lacking, management terms are ever longer. Interview by Jan Thomasson]. PMID- 6926527 TI - 17th annual IMPI symposium (International Microwave Power Institute). Summaries of technical papers. PMID- 6926526 TI - [The new medical education. Greater emphasis on social and behavioral sciences]. PMID- 6926528 TI - Effect of low-level microwave irradiation on the duodenal electrical activity of the unanesthetized rat. AB - The effects of low-level microwave irradiation (5 and 7.5 mW/cm2 at 2.45 GHz) on duodenal electrical activity (slow waves and action potentials) were studied in the unanesthetized rat by way of chronically implanted electrodes. Exposure to microwaves occurred in a cavity for 1 to 4 hours. The specific absorption rates (SAR) were measured at 5.35, 6.05, and 7.04 mW/g, respectively, under 5, 7.5, and 10 mW/cm2 of incident radiation. The results, obtained on seven rats, showed that microwaves usually produce an accelerating effect on the slow waves, and a specific inhibitory effect on action potentials. Those effects appear to be directly dependent on the SAR. PMID- 6926529 TI - Lack of mutagenic effects on conidia of Aspergillus amstelodami irradiated by 8.7175-GHz CW microwaves. AB - Conidial suspensions of Aspergillus amstelodami were exposed to 8.7175-GHz CW microwaves in the near field of a horn antenna. Conidia were irradiated for 3- and 6-hour time intervals and at a temperature ranging between 28 and 30 degrees C. The density of microwave power incident on the suspension was 2.09 mW/cm2. Two types of mutant, conidial colour variants and 8-azaguanine resistant mutants, were looked for. The treatment produced no significant change in the frequencies at which the two classes of mutant were recovered among the survivors as compared with their frequencies from the untreated conidial suspension. Doubling the exposure time did not alter the outcome. PMID- 6926530 TI - The lost art of nursing. PMID- 6926531 TI - Eulogy for a diploma nursing school. PMID- 6926532 TI - The therapeutic use of music: a literature review. PMID- 6926534 TI - The effect of status and gender on interpersonal relationships in nursing. PMID- 6926533 TI - The menstrual myth revisited. AB - In an age when research is sweeping away many long-held medical misconceptions, the body of knowledge surrounding women's menstrual cycle remains tainted by age old myths and taboos. These myths not only reflect inaccuracies, but also perpetuate "theories" about women's behavior that can be detrimental. It is not only in the personal realm, but in the political as well, that this issue gains importance. As long as policy-makers are influenced by suspicions about cyclic symptoms, women's emotional and intellectual stability will be questioned, with consequent repercussions in disability and employment practices. As nurses we have a vested interest in investigations that will establish a new data base from which to draw fresh insights, not only because it is relevant for female clients, but also because nursing as a profession is composed largely of women. As Wilma Scott Heide (1973) observes, "nursing suffers from the same oppression, prejudices, and limitations as women in our society." In other words, the problems of women are the problems of nursing. PMID- 6926535 TI - Is abortion morally justifiable? PMID- 6926537 TI - Does mixing pancreatic enzyme microspheres (Pancrease) with food damage the enteric coating? AB - Supplemental pancreatic enzymes are required for the treatment of malabsorption associated with cystic fibrosis. It is a general practice for enzymes to be sprinkled on, or administered in, food given to infants or children who require pancreatic enzyme replacement. We tested the effect of in vitro incubation of enteric-coated pancreatic enzyme microspheres with infant foods on total recoverable enzyme activity and on the enteric coating. Incubation of enzyme beads with foods with pH greater than 5 (i.e., chicken pH 6.5, veal pH 6.3, and green beans pH 5.6) was without significant effect on either parameter. There was a statistically significant, albeit minor, reduction in maximum enzyme activity recovered following incubation with applesauce (pH 3.5). In addition, the thickness of the enteric coating was significantly reduced. Whether changes in the enzyme beads results in improved or diminished efficiency of therapy remains to be determined. Lipase, unprotected by enteric coating, was rapidly inactivated in applesauce, emphasizing the need to instruct parents about which foods to avoid when administering pancreatic enzymes without enteric coating. PMID- 6926536 TI - A fatal infection caused by methicillin-resistant Staphylococcus aureus acquiring resistance to gentamicin and fusidic acid during therapy. PMID- 6926539 TI - Techniques for handling patients. PMID- 6926540 TI - Pressure sore! PMID- 6926541 TI - Dangerous workplace or dangerous worker? PMID- 6926538 TI - Studies on the cause of hyperuricosuria in cystic fibrosis patients. AB - Qualitative and quantitative analyses of the purine contents of 24 pancreatic enzyme preparations currently available in the Federal Republic of Germany were carried out; guanine, adenine, and hypoxanthine were demonstrated in all drugs examined. The contamination level per dosage unit ranged from 2 to 10 mg urate equivalents, which, after purine absorption and metabolism, must be excreted by the kidneys. Although the additional daily urate intake through the ingestion of pancreatic enzyme preparations was less than 70 mg in 16 of 18 cystic fibrosis patients, uric acid excretion was astoundingly high. Compared to the amount of urate excreted in the urine over a 24-h period, urate intake through pancreatic enzyme preparations was so low that these drugs do not represent an important contributing factor for hyperuricosuria. A clear-cut relationship could be demonstrated between the urinary urate concentration and the severity of the disease. The increased catabolism of these patients therefore is more likely the real cause of the hyperuricosuria demonstrable in most cases. Increased fluid intake and administration of allopurinol proved to be an extremely effective means of controlling hyperuricosuria; no side effects were observed. PMID- 6926542 TI - The clash of cultures--health care. PMID- 6926543 TI - Power and influence in health. PMID- 6926544 TI - Politics of health. PMID- 6926545 TI - Health: whose responsibility? PMID- 6926546 TI - Health: a sociological perspective. PMID- 6926547 TI - Individual or collective responsibility for health. PMID- 6926551 TI - Health practices: drug abuse. PMID- 6926549 TI - Health practices: problems of dietary change. PMID- 6926548 TI - Providing education about health. PMID- 6926550 TI - Health practices: family planning and sex education. PMID- 6926552 TI - Health practices: exercise. PMID- 6926553 TI - Nurses smoking. PMID- 6926554 TI - Children's concepts of health. PMID- 6926556 TI - Health education: nursing curricula. PMID- 6926555 TI - Health education in schools. PMID- 6926558 TI - Health education: antenatal health visiting. PMID- 6926559 TI - Health education: district nursing. PMID- 6926561 TI - Mental health: which ideology? PMID- 6926560 TI - Health education: health visiting. PMID- 6926557 TI - Health education in clinical practice: general nursing. PMID- 6926562 TI - The social mode in psychiatry. PMID- 6926563 TI - Reply to the social mode. PMID- 6926564 TI - The behavioural model. PMID- 6926565 TI - Reply to the behavioural model. PMID- 6926567 TI - Reply to the psychoanalytic view. PMID- 6926566 TI - The psychoanalytic mode in psychiatry. PMID- 6926568 TI - Development of psychiatric nurse education. PMID- 6926570 TI - Drugs in nursing: drug bioavailability. PMID- 6926569 TI - Women and depression. PMID- 6926572 TI - Nutrition. Part 1. Introduction. PMID- 6926571 TI - Communicating nutrition information. PMID- 6926574 TI - The human diet. PMID- 6926573 TI - The digestive system. PMID- 6926575 TI - Feeding the patient - a team effort. PMID- 6926577 TI - Nutrition part 2. Malabsorption. PMID- 6926576 TI - Nutritional assessment. PMID- 6926578 TI - Obesity and anorexia nervosa. PMID- 6926579 TI - Oral nutritional supplements. PMID- 6926580 TI - Nutrition and cancer patients. PMID- 6926581 TI - Adverse reactions to food. PMID- 6926582 TI - Low residue enteral diets in bowel preparation. PMID- 6926583 TI - The immune system: introduction. PMID- 6926584 TI - Immunization. PMID- 6926585 TI - Other immunizations. PMID- 6926587 TI - Drugs in nursing: anti-inflammatory drugs. PMID- 6926588 TI - Inappropriate immunity: bites and stings. PMID- 6926586 TI - Inappropriate immunity: hay fever and its management. PMID- 6926590 TI - Infection. PMID- 6926589 TI - Future trends in clinical immunology. PMID- 6926591 TI - Epidemiology: the spread of infection. PMID- 6926592 TI - Treatment of infection. PMID- 6926593 TI - Intravenous therapy. PMID- 6926594 TI - The use of chemical disinfectants in hospital. PMID- 6926595 TI - Infectious diseases. PMID- 6926596 TI - Aseptic technique in the theatre. PMID- 6926598 TI - Asepsis: the Hampshire dressing aid. PMID- 6926597 TI - Asepsis: theatre drapes and apparel - growing support for the single-use concept. PMID- 6926599 TI - Infection in the catheterized patient. PMID- 6926600 TI - Sexually transmitted disease and sex education. PMID- 6926601 TI - Isolation and barrier nursing. PMID- 6926603 TI - Manufacture and irradiation sterilization of sterile medical products. PMID- 6926602 TI - Wound dressing techniques. PMID- 6926604 TI - Medical equipment. PMID- 6926605 TI - Prevention of infection. PMID- 6926606 TI - The equipment resource. PMID- 6926607 TI - Final evaluation report of student nurse affiliates in community health nursing. PMID- 6926608 TI - National Orthopedic Hospital and Rehabilitation Medicine Center proposal. PMID- 6926609 TI - What community health nursing means to me. PMID- 6926610 TI - Functions and activities of the public health nurse in rural health service. From the Project Management Staff, Ministry of Health. PMID- 6926611 TI - [The effect of air pollution around a cement factory on ventilatory lung function in school children]. PMID- 6926612 TI - Blood loss analyzer. PMID- 6926613 TI - Emanuel Hospital, Portland, Oregon. PMID- 6926614 TI - Computers in nursing. PMID- 6926615 TI - ICU design. PMID- 6926617 TI - [New trends in the care of newborn infants]. PMID- 6926616 TI - [New trends in maternal and infant care during the perinatal period]. PMID- 6926618 TI - [Guidance on sexual activities, sex education, and midwives]. PMID- 6926621 TI - [Sex and sex education: questions and answers]. PMID- 6926619 TI - [Sex and sex education of the adolescent - with special reference to guidance at menarche and the role of the mother]. PMID- 6926620 TI - [Sex education at school]. PMID- 6926622 TI - [Problems concerning midwives - at opening of an ambulatory care facility manned by midwives]. PMID- 6926623 TI - [Problems concerning midwifery duties]. PMID- 6926625 TI - [Questions and answers on midwifery services]. PMID- 6926626 TI - [Psychology of women during and after pregnancy]. PMID- 6926624 TI - [Survey on the midwives' attitude toward obstetrical ambulatory care services manned mainly by midwives]. PMID- 6926627 TI - [Methods of clinical training in midwifery and educational evaluation]. PMID- 6926628 TI - [Area hospitals and nursing education]. PMID- 6926629 TI - [The weight of the nursing processes in the basic educational curriculum and formation of the teaching plan]. PMID- 6926630 TI - [Teaching of nursing courses of students]. PMID- 6926631 TI - [The position of the study of nursing processes in the basic nursing courses]. PMID- 6926634 TI - [Public health nursing activities at the land reclamation projects at the Nasu area, Tochigi Prefecture: achievement of Mrs. Sen Hirai]. PMID- 6926633 TI - [In search of educational humanity. (10). On theories concerning teachers, 1]. PMID- 6926635 TI - [Public health nursing activities at the land reclamation projects at the Nasu area, Tochigi Prefecture. Contribution of Ms. Minako Fushimi]. PMID- 6926632 TI - [On nursing education. 4. The current status of nursing education in England and the United States]. PMID- 6926636 TI - [Public health nursing activities at the land reclamation projects at the Nasu area, Tochigi Prefecture. Support of every phase of inhibitants' life: activities of Ms. Haruko Miyanaga]. PMID- 6926637 TI - [Search of the origin of public health nursing activities: differences between the activities at land reclamation projects and modern public health nursing. The past and present of public health nursing at the Nasu area, Tochigi prefecture. A discussion]. PMID- 6926641 TI - [Public health nursing of patients with refractory diseases]. PMID- 6926639 TI - [Land reclamation projects at Tochigi Prefecture]. PMID- 6926638 TI - [Achievement of public health nurses at the land reclamation projects of Tochigi Prefecture]. PMID- 6926640 TI - [Legislation and implementation of primary health care (2). Organization of citizens' groups for promotion of health - examples at Matsudo-shi]. PMID- 6926642 TI - [Public health and the life style - a behavioral approach]. PMID- 6926643 TI - [NHS in Scotland and Denmark. Old and new towns for the aged]. PMID- 6926644 TI - [Support of a family unable to be self-sufficient and being cared for at a public facility]. PMID- 6926645 TI - [Nursing involved in excretion (5)]. PMID- 6926646 TI - [Problems in incorporating various public health projects - maximum utilization of the coordinating capacity]. PMID- 6926647 TI - Acceptance of ostomy and the visitor role in a self-help group for ostomy patients. AB - The helper therapy principle, which underscores the benefits from helping another person, has been relatively unexplored in the self-help movement. This study examined whether persons enrolled in the United Ostomy Association, a self-help group for ostomates, who functioned in a helping role as visitors demonstrated a greater level of acceptance of their ostomy than those persons enrolled in the same group who have not served in the visitor role. Results indicated that visitors' acceptance of their own ostomies was significantly higher than nonvisitors'. The length of time since visitors and nonvisitors had their first ostomy surgery was not a significant factor in the person's acceptance of ostomy. There was a significant relationship between the person's level of acceptance of ostomy and the length of time the individual had served in the visitor role. Serving in the visitor role contributed significantly to predicting a higher level of acceptance of the ostomy. The length of time since surgery was a significant predictor to serving in the visitor role. Factors of age, sex, type of ostomy, and length of time since surgery did not contribute significantly to predicting a higher level of acceptance of the ostomy. PMID- 6926648 TI - Stress identification and coping patterns in patients on hemodialysis. AB - The types and severity of stressors and methods of coping with stress were assessed for 35 patients on hemodialysis. Coping was measured with a tested scale and stress was evaluated with a scale developed for the study. Test-retest reliability of the stressor scale was satisfactory (rs = .71). Results indicated that stressors experienced by the hemodialysis patient can be measured with an objective tool; psychosocial stressors have an impact equal to that of physiological stressors. Fluid restriction was ranked as the highest psychosocial stressor and the top physiological stressors were muscle cramps and fatigue. Patients on dialysis for one to three years indicated the greatest amount of stress. Patients used problem-oriented coping methods significantly more than affective-oriented methods (t [34] = 7.06), p greater than .001). Optimism and controlling the situation were the two most common coping methods, and putting the problem out of one's mind and blaming someone else were the least important coping tools. PMID- 6926650 TI - Low-cost research: a project on a shoestring. PMID- 6926649 TI - Experienced personal control and quality of life in late-stage cancer patients. AB - This study examined the association of experienced personal control and quality of life for late-stage cancer patients within the context of Rotter's Social Learning Theory and Seligman's Theory of Learned Helplessness. It was hypothesized that in late-stage cancer patients greater control would be associated with a higher quality of life as measured by self-esteem, anxiety, and perceived self-esteem, anxiety, and perceived meaningfulness. The longer the history of the disease, the lower would be the individual's level of experienced personal control and quality of life. Fifty-seven late-stage cancer patients completed four standardized instruments: the Rosenberg Self-Esteem Scale; the Health Locus of Control Scale (HLC); the Lewis, Firsich, and Parsell Attorney Scale; and the Crumbaugh Purpose-in-Life Test. As predicted, the measure of experienced personal control over life significantly correlated with scores on the self-esteem scale (tau = -.33; p = .001), and the anxiety scale (tau = -.30; p = .001). Contrary to prediction, scores on the Health Locus of Control Scale were only significantly associated with scores on the Purpose-In-Life Test (tau = -.18; p = .05). Length of history of disease was significantly related to scores on the HLC Scale (tau = .27; p = .007) and to scores on the anxiety scale (tau = .20; p = .03) but was not significantly associated with scores on the self-esteem scale or the Purpose-In-Life Test. PMID- 6926651 TI - Maternal attachment behavior and the mother's self-concept: the effect of early skin-to-skin contact. AB - The problem was to determine the effect of skin-to-skin contact between mother and infant during the first hour following delivery on later maternal attachment behavior and self concept. Twenty primiparous women were randomly assigned skin to-skin contact with their infant during the first hour after birth. There were no significant differences in 36-hour or three-month attachment behaviors or in prenatal or three month self-concept scores. For most mothers, first time motherhood appeared to have a positive effect on their self-concepts. PMID- 6926652 TI - Perception of parents' behavior and children's general fearfulness. AB - A study was conducted to investigate the relationship between perception of parents' support, punishment, control, and encouragement of autonomy and general fearfulness in ten- to eleven-year-old girls. Subjects included 68 girls in the fifth and sixth grades. The Cornell Parent Behavior Description Questionnaire was used as a measure of the girls' perception of their parents' support, punishment, control, and autonomy-granting. Geer's Fear Survey Schedule II-Modified was used as a measure of the girls' general fearfulness. A low significant positive correlation (r = 0.215) between the girls' perception of their parents' punishment and the girls' general fearfulness was observed. Also observed were: a low significant negative correlation (r = -0.201) between the girls' perception of their parents' encouragement of autonomy and the girls' general fearfulness and, contrary to expectation, a slight negative correlation (r = 0.173) between the girls' perception of their parents' support and the girl's general fearfulness. A slight negative correlation (r = -0.109) appeared between the girls' perception of their parents' control and the girls' general fearfulness. An auxiliary finding was that the girls perceived their mothers as more supportive, punitive, and controlling than their fathers. Upper middle-class parents were viewed by their daughters as less punitive and more autonomy granting than lower middle-class parents. PMID- 6926653 TI - Measurement of the nurse organizational climate of neonatal intensive care units. AB - The concept of organizational climate is important for the study and understanding of work organizations. Researchers have not yet studied the organizational climate of hospital intensive care units, so it is not clear that the dimensions useful in description of other work settings will be appropriate for conceptualizing neonatal intensive care units (NICU's). This study investigated nurse perceptions of the organizational climate of NICU's in a sample of 18 hospitals. The Organizational Climate Description Questionnaire was modified for use in the NICU setting. A set of homogeneous climate scales was developed from the revised instrument. The six scales of the resulting instrument, the Nursing Organizational Climate Description Questionnaire, Form B (NOCDQ-B), demonstrated median internal-consistency reliability of .69 on cross validation. Analysis of variance indicated that each of the six NOCDQ-B dimensions served to differentiate the NICU's in the study. Further, significant relationships were found at the unit mean level between three of the six NOCDQ-B scales and nurse satisfaction, as measured by the Minnesota Satisfaction Questionnaire. PMID- 6926654 TI - Cancer as crisis: the critical elements of adjustment. AB - This study examined the course and duration of the crisis inherent in the diagnosis and treatment of cancer in women. Three groups of female patients, breast cancer, gynecological cancer, and breast biopsy patients, were compared on the variables of depression and body image. The women were assessed prior to surgery and at one- and two-month intervals in order to determine whether their crises had been resolved within the normal six-month framework. An additional follow-up was made after 20 months to evaluate any long-term effects of the diagnosis of cancer or its treatment. Results of the study revealed that only breast biopsy and mastectomy patients adapted appropriately and were able to resolve their crises. In examining the gynecological cancer patients, initial feelings of depression and body image continued to worsen even at 20 months following surgery. Implications for nursing practice are discussed, and suggestions for future research are presented. PMID- 6926658 TI - [Symposium on the study of modifications in the curriculum of the School of Nursing of the Sao Paulo University]. PMID- 6926655 TI - [Acceptance, empathy and emotional involvement in the nurse-patient relationship]. PMID- 6926656 TI - [Drugs and nutrition: interactions and incompatibilities]. PMID- 6926657 TI - [Prevention levels in industrial nursing]. PMID- 6926659 TI - Effect of vibration on the activity of the plasma kallikrein-kinin system in the rat. AB - Rats were exposed to whole body vibration horizontally for four hours at 5 Hz frequency and 2 cm amplitude. Of the components of the plasma kallikrein-kinin system the free (spontaneous) and kaolin-activated kallikrein (prekallikrein) activities, the concentration of bradykinin, the bradykinin splitting total kininase activity, total kallikrein-inhibitor activity and the concentration of alpha 2-macroglobulin, a major plasma kallikrein inhibitor, were estimated. Results showed that in response to acute vibration plasma free kallikrein activity was increased significantly in association with a significant reduction of prekallikrein concentration. The concentrations of bradykinin and total kininase activity were significantly elevated, too. Neither total kallikrein inhibitor activity nor the concentration of alpha 2-macroglobulin were changed indicating that the plasma kallikrein inhibitors did not play a role in the alterations of plasma free kallikrein and prekallikrein activities. During acute vibration the plasma kallikrein-kinin system was activated probably by the enhanced catecholamine secretion. We suggest that the biological importance of this phenomenon is in the defense against the impaired microcirculation caused by catecholamines. PMID- 6926660 TI - A great nursing challenge--recognition and effective management of the patient with herpes simplex encephalitis. AB - There are many difficulties associated with management of persons suspected or diagnosed with HSE. Excellent coordinated care is critical and the health care team must devote particular attention to these patients' complex clinical problems, including nutrition. While Vira-A therapy as the treatment for diagnosed HSE is significant, it may be associated with difficulties in fluid overload. Other problems are likely to evolve around a serious illness that progresses rapidly and is associated with fever, seizures, and increased intracranial pressure. PMID- 6926661 TI - A teaching tool for spinal cord injured patients. PMID- 6926662 TI - Are you a creative nurse? PMID- 6926663 TI - The patient in the persistent vegetative state. PMID- 6926664 TI - Nursing considerations in formulating a care plan: a case study. PMID- 6926665 TI - An introduction to nursing research. PMID- 6926666 TI - A post-insertion protocol for management of the Olympic Tracheostomy Button in neurosurgical patients. AB - This article describes and suggests a protocol for the monitoring and management of problems relating to the use of the Olympic Tracheostomy button with special emphasis on the needs of neurosurgical patients. A description of the Olympic Tracheostomy button is accompanied by a systematic checklist for nursing care supplemented by supporting rationale. The existence and availability of such a protocol for this patient group should focus the concern of all nursing personnel in a unified and orderly manner and heighten the index of suspicion for problems which may be subtle but potentially life-threatening. PMID- 6926667 TI - Transsphenoidal hypophysectomy. PMID- 6926668 TI - Nursing management of diabetes insipidus. AB - Diabetes insipidus is seen most frequently in neurosurgical patients. The transient form is more common and usually subsides prior to discharge. Permanent DI is seen in patients with extensive damage in the hypothalamic area. Treatment of either form of DI is usually with a preparation of vasopressin. Nursing assessements and interventions are crucial to a successful outcome in patients with this disorder. Health teaching for patients with permanent DI is an integral part of the nursing responsibility. PMID- 6926669 TI - The effect of preoperative instruction on state anxiety. AB - State anxiety was measured in 81 patients scheduled for back and neck surgery before and after preoperative instruction. Anxiety levels were significantly reduced after instruction was given. In 12 patients, anxiety level increased after instruction, possibly because of the removal of denial as a coping mechanism or because these patients were generally more anxious. There was no difference in hospital stay or number of analgesics received postoperatively between the group whose scores decreased and the group whose scores increased. The Increased Score Group, however, displayed more behavioral manifestations of anxiety after instruction and postoperatively. This study provides further evidence of the psychological benefit of preoperative instruction. Instruction should be provided on a consistent basis utilizing a structured format and including the patient's family. PMID- 6926671 TI - Myelomeningocele: a multidisciplinary problem. PMID- 6926670 TI - Nursing care of the patient with hydrocephalus. AB - Hydrocephalus is a neurological disorder seen frequently in the pediatric population and less frequently in adults. Treatment is directed toward removing the lesion causing the obstruction. Frequently a shunting device is needed to restore and/or maintain CSF flow. The prognosis of these patients is based on a variety of factors. Nursing observations and intervention are of the utmost importance to recognize and/or prevent serious complications postoperatively. Long-term studies to evaluate the prognosis of these patients are limited. PMID- 6926672 TI - Survey of neurogenic bladder in multiple sclerosis. PMID- 6926673 TI - Drug stop. Iatrogenic barbiturate coma in severe head injury. PMID- 6926674 TI - Speech during the oath-taking ceremonies of new nurses at the plenary hall, Philippine International Convention Center (PICC), on August 26, 1982. PMID- 6926675 TI - Breakthrough: the story of Adema. PMID- 6926676 TI - Primary health care: is it bridging the gap between the health care of our poor and the rich? PMID- 6926677 TI - Development and achievement of standards of nursing service administration. PMID- 6926678 TI - The partnership approach to health development: Bagong Silangan Nursing Clinic Project. Part II. Experiences, lessons and realities. PMID- 6926679 TI - Standard for prenatal care service (individual level). PMID- 6926680 TI - The partnership approach to health development: Bagong Silangan Nursing Clinic Project. Part I. A case presentation. PMID- 6926681 TI - Bagong Silangan community diagnosis. Committee on the Bagong Silangan Nursing Clinic Project. PMID- 6926682 TI - Clinical and experimental studies on "Shengji (tissue-growing)" ointment in infected open fractures. PMID- 6926683 TI - Cine-cholangiographic studies of Artemisia decoction on the dynamics of Oddi's sphincter of common bile duct. PMID- 6926684 TI - Effect of extracts of Spirobolus bungii on transplanted tumors in mice. PMID- 6926685 TI - Studies on propagated sensation along channels. Present status and future prospects. PMID- 6926686 TI - Observation of the effect of Spirobolus bungii extract on cancer cells. PMID- 6926688 TI - Helium-neon laser irradiation of acupuncture points in treatment of 50 cases of acute appendicitis. PMID- 6926687 TI - Volvulus of the stomach successfully treated with acupuncture report of 9 cases. PMID- 6926689 TI - Observation on treatment of post-operative anal pain with embedded needle. PMID- 6926690 TI - Treatment of hereditary cerebellar ataxia with Ganoderma capense. Report of 4 cases. PMID- 6926691 TI - Observation on the effect of acupuncture treatment in 300 cases of primary trigeminal neuralgia. PMID- 6926692 TI - Cure of two patients with functional ejaculatio deficient. PMID- 6926693 TI - Effect of "Qingshen" No. 1 in 50 cases of simple obesity. PMID- 6926694 TI - Clinical observation of 26 cases of idiopathic thrombocytopenic purpura treated with Sarcandra glaber. PMID- 6926695 TI - Treatment of trichomonal enteritis by Chinese medicinal herbs. Report of 16 cases. PMID- 6926696 TI - The effect of acupuncture in curing the smoking habit, 210 cases. PMID- 6926697 TI - Effect of traditional massage on closure insufficiency of glottis in singers. An analysis of 16 cases. PMID- 6926698 TI - The effect and abuse syndrome of Ginseng. PMID- 6926699 TI - Research on the mechanism of "Qigong (breathing exercise)". A preliminary study on its effect in balancing "Yin" and "Yang", regulating circulation and promoting flow in the meridian system. PMID- 6926701 TI - [Attitude of nurses towards euthanasia of terminally ill patients]. PMID- 6926700 TI - Lectures on essentials of traditional Chinese medicine. PMID- 6926703 TI - [The development of language in children]. PMID- 6926702 TI - [The treatment of rape victims - a challenge for nurses]. PMID- 6926704 TI - [A project for the elderly (geriatrics)]. PMID- 6926705 TI - [Professional language; a means of communication in hospitals]. PMID- 6926706 TI - [Study tour in England]. PMID- 6926708 TI - [First International Congress on Nursing Law & Ethics - Jerusalem]. PMID- 6926707 TI - [Burnout in intensive care units for premature infants]. PMID- 6926709 TI - [Nursing care aspects of a newborn infant with a congenital defect]. PMID- 6926710 TI - [Selected papers from the 3d Israeli Nursing Conference. Influence of the professional association on the quality of care]. PMID- 6926711 TI - [Selected papers from the 3d Israeli Nursing Conference. Importance of standards in giving quality care]. PMID- 6926712 TI - [Selected papers from the 3d Israeli Nursing Conference. Standards in psychiatric nursing care]. PMID- 6926713 TI - [Work satisfaction among nurses - a research study]. PMID- 6926714 TI - [Once again the nursing process]. PMID- 6926715 TI - [Survey of a 4-year R.N. program for adults]. PMID- 6926716 TI - [Improving the image of the mentally ill in the community]. PMID- 6926717 TI - [Nursing in diabetes]. PMID- 6926718 TI - [Teaching of patients by RNs]. PMID- 6926720 TI - [The importance of instructing children and their parents before elective surgery]. PMID- 6926721 TI - [Instructing families in the control of pediculosis]. PMID- 6926722 TI - [Teaching of patients by RNs]. PMID- 6926723 TI - [Instructing mothers in breast feeding in the maternity ward of Beilinson Medical Center]. PMID- 6926724 TI - [Treatment of hemiplegia according to the Bobath method]. PMID- 6926725 TI - [Guiding project for patients treated with ambulatory peritoneal dialysis]. PMID- 6926727 TI - [Enzymes and myopathies]. PMID- 6926726 TI - Genetic analysis of the processing of a spliced tRNA. AB - We analyzed the effect of 18 single nucleotide changes on the processing of the transcripts produced by cloned yeast tRNATyr genes after microinjection into the nucleus of living Xenopus oocytes. The processing step most easily blocked by mutation is the early maturation of the 5' and 3' termini of the tRNATyr primary transcript, involving removal of 5'-leader and 3'-trailer sequences and CCA addition. The enzymes seem to recognize the whole tRNA cloverleaf structure since mutations in all regions of the molecule can stop processing. Mutations that affect splicing of the 92-nucleotide precursor (which has mature ends but still contains the intervening sequence, and is the normal substrate for the splicing enzymes), are located in the vicinity of the intervening sequence. Base modification enzymes that add pseudouridine, 1-methyladenosine and 5 methylcytosine appear rather insensitive to changes in secondary and tertiary structure of early transcripts in the 16 mutants examined. These enzymes may recognize only limited regions of the precursor RNA. RNA polymerase III behaves as if able to count the number of Us added before termination; and aberrant termination products in two mutants suggest that the secondary structure of the nascent transcript can be very imortant in eukaryotic transcription termination. PMID- 6926729 TI - [Drug data (lorazepam)]. PMID- 6926728 TI - [Current focus on curricular revision]. PMID- 6926730 TI - [Nursing care to the individual with transfrontal hypophysectomy]. PMID- 6926731 TI - Staffing pattern of health personnel in rural health units. PMID- 6926732 TI - Country report: maternal and child health in the Philippines. PMID- 6926733 TI - Orthotics and prosthetics. PMID- 6926734 TI - The double-edged sword: paternalism as a policy in the problems of aging. AB - Paternalism--coercive or deceptive interference in a citizen's life for his own good--is much in evidence in our policies regarding the aged. Some argue that paternalism is an unwarranted denial of individual liberty, ,for doubtful societal gain. Others contend that freedom has but instrumental value, and the aged cannot always use it effectively to aid in pursuit of their own happiness. The philosophical and political choices made on behalf of the aged must be understood as imperfect compromises. PMID- 6926735 TI - Medical malpractice: some implications of contract and arbitration in HMOs. AB - The "crisis" of medical malpractice has led to increasing advocacy of abandoning the fault-finding and litigation approaches. Health maintenance organizations (HMOs) afford unique institutional settings for developing alternatives. Explicit contracts between provider-managers and member-patients can allow consumers to determine how risk-prevention-and overall quality-they are willing to invest in. Not just principles of economic efficiency, but also of distributional equity can inform HMO performance-standard contracts; and arbitration may be the best mode for managing disputes arising from them. PMID- 6926737 TI - Breast reconstruction after mastectomy. AB - Breast reconstruction after mastectomy is discussed with emphasis on present surgical techniques and results achieved. The deformity is defined and the goals outlined. Contra-indications, indications, evaluation of the patient and proper choice of reconstructive procedures and implantable materials are reviewed as well as complications and restrictions. Selective illustrations demonstrate some of the clinical experience of patients treated at Memorial-Sloan Kettering Cancer Center. PMID- 6926736 TI - Metabolism of ketone bodies in pregnant sheep. AB - A combination of isotope-dilution and arteriovenous-difference techniques was used to determine the significance of ketones to energy homoeostasis in fasted pregnant ewes. 2. There was incomplete interconversion of D(-) 3-hydroxybutyrate (3HB) and acetoacetate (AcAc) and therefore neither entry rate nor oxidation of total ketone bodies could be estimated by assuming circulating ketone bodies represent a single metabolic compartment. Total ketone body metabolism was satisfactorily summarized using a three-compartment model. In fasted pregnant ewes the mean entry rate of total ketones was 1 mmol/h per kg body-weight and of the ketones entering the circulating 87% were promptly oxidized to carbon dioxide accounting for 30% of the total CO2 production. 3. Ketone bodies are readily utilized by hind-limb skeletal muscle such that if completely oxidized, 18 +/- 4 and 48 +/- 3% of the oxygen utilized could be accounted for in fed and fasted pregnant ewes respectively. For both 3HB and AcAc there was a hyperbolic relationship between utilization and arterial concentration. The apparent Michaelis constant (Km) values were 0.55 and 1.42 mM respectively and the maximum velocity (Vmax) 2.9 and 5.6 mmol/h per kg muscle. The arterial concentration of AcAc is always below the Km value and this limits the utilization rate. THe D(-) 3HB concentration however, may surpass that required for maximum utilization and ketoacidosis may be a consequence of this. 4. A two-compartment model was used to analyse ketone body metabolism by hind-limb skeletal muscle. The results suggested substantial interconversion and production of AcAc and 3HB. 5. The pregnant uterus utilized 3HB which if completely oxidized accounted for 12 +/- 2 (fed) and 25 +/- 4 (fasted) % of its O2 consumption. At least 64% of the net 3HB utilized was oxidized. AcAc was not utilized in significant quantitites. PMID- 6926738 TI - Carcinoma of the thyroid gland. AB - Thyroid cancer is not a common cancer and consists of a variety of tumors with different biological characteristics. Diagnosis and therapeutic approaches differ considerably, depending on which subgroup the tumor belongs to. Differentiated carcinomas, which constitute the bulk of thyroid carcinoma, often retain the features of the thyroid gland, which can be taken advantage of in their management. The prognosis of these patients is usually excellent. Undifferentiated carcinoma, in contrast, is an aggressive tumor and usually is fatal within a year from the diagnosis. Therefore, an aggressive therapeutic approach is required. Transformation of differentiated carcinoma to undifferentiated carcinoma does occur, although infrequently. The importance of proper management of patients with differentiated carcinoma is obvious. Medullary carcinoma, which originates from the parafollicular cells, has various interesting biological characteristics and is a medium-grade malignancy. PMID- 6926739 TI - Advances in the treatment of pancreatic cancer. AB - Conventional pancreatic resections have proved unsatisfactory in the treatment of pancreatic cancer. A new operative approach that includes resection of the pancreas en bloc with the regional nodes and pertinent vascular structures has been developed. The procedure was carried out in 27 patients, the majority of whom had advanced neoplasms. The two-year actuarial survival of those who escaped complications of the procedure and lived was 46%. The technical details, postoperative problems, and the benefits of this operation are discussed. PMID- 6926740 TI - Squamous cell carcinoma of the skin of the extremities. AB - Nonmelanomatous skin cancer usually occurs in fair-skinned persons on sites chronically exposed to sunlight. In a series of 35,000 patients with skin cancer seen at M. D. Anderson Hospital and Tumor Institute, 1,208 patients (13%) had squamous cell skin cancer of the extremities. Forty-one of these patients had a clear history of a preexisting thermal burn or irradiation dermatitis (Marjolin's ulcer). The average lesion was over 2 cm in diameter, and the average Marjolin's ulcer was over 5 cm. The treatment of choice in this series of relatively large lesions was surgical excision with or without skin grafting and with histologic evaluation of the surgical margins. The local recurrence rate was less than 10%. Regional metastasis developed in 1.4% of the patients and in 44% of those with Marjolin's ulcer. Even with prompt nodal dissection, the five-year survival rate for patients with nodal metastasis was only 35%. The presence of extracapsular spread of nodal disease is of grave significance, and adjunctive radiation therapy should be considered. Careful follow-up of all patients with squamous cell skin cancer is important. PMID- 6926741 TI - Current trends in post-laryngectomy speech rehabilitation. AB - In recent years there has been considerable interest in exploration of surgical speech rehabilitation (SSR) for the laryngectomee as an alternative to conventional management. The history of the evolution of present pneumatic and electronic methods is traced. The details of the various methods are analyzed including the phonatory neoglottis method reported by Staffieri. Algorithms are offered for the patient who is about to undergo laryngectomy, for the patient who has had laryngectomy in the past, and for the patient facing total pharyngolaryngectomy. The prospects for future developments in the field of SSR are analyzed, acknowledging that none of the present methods provides an ideal solution to the problem of laryngeal aphonia. PMID- 6926742 TI - Breast reconstruction following mastectomy. AB - The mutilating effect of surgery for cancer of the breast has left many women needful of reconstruction to restore the body contour and self-image. Reconstruction involves replacement of the three elements that have been lost: breast mass, skin, muscle and nipple-areolar complex. Methods for accomplishing this have been devised and are in common use. Because of the increased predisposition to malignancy in the remaining breast and the difficulty in achieving symmetry in both breasts, the remaining breast must be considered, with subcutaneous mastectomy being the most appropriate course in most cases. Patient acceptance has been excellent. PMID- 6926743 TI - Early cancer of the esophagus: diagnosis and clinical evaluation. PMID- 6926744 TI - Primary tumors of the esophagus other than squamous cell carcinoma--histologic classification and statistics in the surgical and autopsied materials in Japan. AB - Clinicopathological features of 405 patients with esophageal tumors other than squamous cell carcinoma, which were resected surgically at 68 institutions in Japan, were analyzed and compared with those of 4,995 cases of esophageal malignant neoplasms autopsied during 19 years (1958-1976) in Japan. Of 405 surgical cases, 149 were benign tumors, most of which (89%) were leiomyomas. The incidence of malignant tumors other than squamous cell carcinoma was 2.1% in the surgical, and 7.2% in the autopsied cases of esophageal cancer. Malignancies were classified into 15 histologic types. Most of them did not differ in sex and age incidence or location of the primary site from squamous cell carcinoma, except for adenocarcinomas, in which there was a greater incidence of occurrence in the lower portion of the esophagus. Carcinosarcomas and pseudosarcomas showed peculiar clinical and pathological characteristics. Overall prognosis was poor except in cases of pseudosarcoma and leiomyosarcoma. PMID- 6926745 TI - Computed tomography of the abdomen. AB - In a few short years, computed tomography has become an important diagnostic procedure in the examination of the abdomen and pelvis. Its forte lies in its ability to provide cross-sectional views of excellent anatomical detail. Imaging of deep-seated structures such as the pancreas, adrenal glands, and enlarged retroperitoneal lymph nodes is now possible. The ability to distinguish small variations in tissue density enables the radiologist to evaluate the texture of solid structures, and to differentiate them from cysts or abscesses. The addition of contrast enhancement makes it possible to determine the vascularity of a lesson. The major limitation of CT is poorer delineation of structures in thin patients, and in patients in whom voluntary and involuntary motion cannot be interrupted. Computed tomography is compared with other complementary imaging procedures to include sonography, radionuclide imaging, and conventional radiograph procedures. It has replaced invasive diagnostic procedures in many instances. In a given situation, one or more imaging modalities may be appropriate. PMID- 6926746 TI - Hemoglobin variant with slight instability and increased oxygen affinity, Hb Etobicoke [alpha 84 (F5) Ser replaced by Arg]: the first case detected in Japan. PMID- 6926747 TI - Advances in percutaneous access device development. PMID- 6926748 TI - Synthesis and properties of the new thiol-specific reagent difluorescein disulfide: its application on histone-histone and histone-DNA interactions. PMID- 6926749 TI - Synthesis of (-)-15-deoxyspergualin and (-)-spergualin-15-phosphate. AB - The method for chemical modification of spergualin with retention of the configuration at the C-11 has been achieved by the use of tetrahydropyranyl group for protection of the 11-hydroxyl group. (-)-15-Deoxyspergualin (2), which shows about eight times stronger inhibition against mouse leukemia L-1210 than the natural (-)-spergualin(1), and (-)-spergualin-15-phosphate(3) possessing a good antitumor activity have been synthesized starting from 1. PMID- 6926750 TI - Chemical and toxicological studies on bracken fern, Pteridium aquilinum var. latiusculum. VI. Isolation of 5-O-caffeoylshikimic acid as an antithiamine factor. PMID- 6926751 TI - Hemodialysis eosinophilia. PMID- 6926753 TI - Symptom survey of residents of homes insulated with urea--formaldehyde foam. PMID- 6926754 TI - Evidence for intracellular digestion of an exogenous protein by rat peritoneal macrophages. AB - The differential effects of lower incubation temperature on the digestion of formaldehyde-denatured 125I-labelled bovine serum albumin by intact rat peritoneal macrophages and by macrophage homogenates were studied. Digestion by intact macrophages was abolished at 20 degrees C and below, but a near-linear relationship between digestion rate and temperature between 37 degrees C and 5 degrees C was found with homogenates. Several known inhibitors of pinocytosis were found to inhibit the generation of digestion products from 125I-labelled albumin by macrophages. It is concluded that pinocytosis is an obligatory step in the catabolism of exogenous proteins by macrophages. PMID- 6926752 TI - [Simultaneous disinfection and sterilization of the apparatus for artificial pulmonary ventilation and inhalation anesthesia]. PMID- 6926755 TI - Primary amine use and other strategies for preventing human exposure to N nitroso compounds: application to cutting fluids. PMID- 6926756 TI - [Induction by formaldehyde of conformational changes from helix to globule in the myoglobin molecule]. AB - The secondary structure of myoglobin, treated with formaldehyde, has been studied by absorption spectroscopy, circular dichroism and gel-chromatography. The chemical modification of protein leads to disturbance of the polypeptide alpha helix and destruction of the heme environment. The unfolding of protein in the presence of formaldehyde is a reversible process, the rate of transition is conditioned by temperature and formaldehyde concentration. At certain temperature conditions and formaldehyde concentration it is possible to obtain completely unfolded protein. The denaturation of myoglobin in the presence of formaldehyde is not cooperative in contrast to classical denaturation by pH, temperature, urea and other agents. Presence of some aminoacids causes inhibition of conformational changes in the protein molecule. Possible mechanisms of denaturation of myoglobin in the presence of formaldehyde are discussed. PMID- 6926758 TI - A serological survey of Rift Valley fever antibodies in the northern Sinai. AB - In the aftermath of an extensive Egyptian Rift Valley fever (RVF) epidemic during 1977-78, RVF activity in the adjacent Sinai peninsula has been inferred from the presence of haemagglutination-inhibition (HI) antibodies in sera from indigenous humans and rodents. We attempted to confirm these findings by HI testing of sera from Israeli soldiers serving in the region of the El Arish Wadi system in the Sinai, and from indigenous rodents. Six of 199 human sera (3.0%) and two of 88 rodent sera (2.3%) were positive, but none reacted in the more specific plaque reduction neutralization test. We conclude that there is no definitive serological evidence for RVF activity in the Sinai and that sera reacting in the HI test must be confirmed by a more specific serological procedure. PMID- 6926759 TI - West Nile virus in Pakistan. 1. Sero-epidemiological studies in Punjab Province. AB - Serum samples collected during 1978-79 from residents of the Chiniot and Changa Manga National Forest (CMF) areas of Punjab Province, Pakistan, had over-all neutralizing (N) antibody positive rates for West Nile (WN) virus of 32.8% (n = 192) and 38.5% (n = 239), respectively. Comparison of the age-specific antibody rates indicated that the pattern of exposure to infection was different in the two areas. Samples from a 1968 serosurvey of residents of the CMF area had an age specific N antibody profile similar to the 1978 CMF sample, but both the over-all N and haemagglutination-inhibition (HI) antibody positive rates were much higher in the 1968 sample. When tested against antigen prepared from the Pakistan I-746 strain of WN virus, the percentage of sera HI antibody positive and the geometric mean titre of the sera were significantly higher than when tested against the Egypt-101 antigen. One of 124 and 11 of 50 sera from the 1978 and 1968 samples from CMF exhibited detectable HI antibody against dengue-3 virus, respectively, indicating cross-reacting flavivirus antibody was present. None of the positive sera had a higher titre against dengue-3 than against WN virus, but four of the 1968 sera reacted to equal titre against both antigens. During the 1978-79 CMF survey, serum samples from domestic and wild animals were tested for WN virus antibody. Of the 317 wild birds captured, 85 were N-antibody positive. The only frequently bled mammal was the Indian cow, from which 21 of 58 samples were positive for WN antibody. PMID- 6926757 TI - [Formalin foot baths in the prevention of interdigital dermatitis in cattle]. AB - Formalin (= approximately 35 per cent formaldehyde) foot baths are used with variable success to prevent interdigital dermatitis, eczema of the interdigital skin accompanied by secondary destruction of the bulb horn. Experimental studies were done in vivo and in vitro to determine the significance of the temperature and concentration of the formalin solution and the method of bathing (standing in a bath for sixty minutes or walking through a bath, in which case each foot is immersed twice in the solution). The results show that a low temperature of the bathing solution (10 degrees C), which theoretically produces poor disinfection (Table 3), does not necessarily imply inadequate disinfection in actual practice (Table 4) as the solution will adhere to the interdigital skin for about thirty minutes (Table 2) and very rapidly will acquire the temperature of the skin (20 degrees-30 degrees C, Table 1). Therefore contact between the interdigital skin and grass, mud, dung and so on has to be prevented for the first thirty minutes after bathing. The more intensive contact between formalin and skin in a stationary foot bath offers advantages over the pass-through bath (Table 4). When a 3 percent formalin solution in a pass-through bath fails to produce satisfactory results, a 5 percent solution may be used. This concentration will result in more effective disinfection (Table 4); higher concentrations may cause skin lesions. Repeated daily disinfection does not produce further reduction of the bacterial flora on the interdigital skin to a significant degree (Table 5). In addition to the disinfecting effect, the hardening effect on the interdigital skin may be of importance. PMID- 6926763 TI - Comparative sensitivity of Naegleria fowleri to amphotericin B and amphotericin B methyl ester. AB - Data presented showed that Naegleria fowleri is much more sensitive to amphotericin B (AmB) than to amphotericin B methyl ester (AME). In vitro, AME was effective at concentrations of 1.0 microgram/ml whereas the parent antibiotic, AmB, was effective at concentrations of 0.0125 to 0.025 microgram/ml. In vivo, AmB, at a concentration of 2.5 mg/kg/day, produced 100% survival in mice infected with N. fowleri, but AME failed to protect infected mice even at concentrations of 30 mg/kg/day. The results support previous observations with fungi which have shown that AmB is a more potent antimicrobial agent than AME. PMID- 6926762 TI - The morphology in culture of the intestinal amoebae of man. PMID- 6926761 TI - Intracranial suppuration complicating tropical pyomyositis. Report of two cases. AB - Tropical pyomyositis complicated by intracranial abscesses is described in two Nigerian male patients, aged five and 50 years. In both cases, the lesions were verified at autopsy. The occurrence of brain abscesses in pyomyositis is briefly reviewed. The complication may not be as rare as previously thought and this will appear if port-mortem examination is performed on most, possibly all, fatal cases of pyomyositis. PMID- 6926760 TI - Studies on the experimental chemotherapy of Angiostrongylus malaysiensis infection in rats with mebendazole and levamisole. AB - The effect of levamisole hydrochloride and mebendazole on Angiostrongylus malaysiensis infection in albino rats was studied. Animals at different stages of infection were treated with various oral doses of levamisole and mebendazole with the aim of finding an effective treatment regime. Levamisole was most effective for treating rats seven days after infection but its efficacy dropped as infection progressed. Mebendazole given at a dose of 1 mg/kg for five days was more effective against early larval stages (97.39% efficacy). At 5 mg/kg for five days mebendazole was more effective than levamisole against all stages of the infection. PMID- 6926764 TI - African sleeping sickness: new evidence that mature tsetse flies (Glossina morsitans) can become potent vectors. AB - Starved mature male tsetse flies (21 to 25 days old) are capable of developing salivary gland (SG) infections of Trypanosoma brucei rhodesiense at rates nearly comparable to teneral males less than 24 hours old when given an infective meal containing parasites, horse red cells and culture medium. Although the over-all SG infection rate for mature males starved for three, four or five days before infection was about half that for teneral males less than 48 hours old (8.0% v. 15.6%), males starved for four days developed infection rates (12.3%) that were comparable to those of teneral flies less than 24 hours old (11.8%). It is suggested that the acquisition of infection by mature flies should be considered when evaluating factors contributing either to maintenance of endemic infections or perhaps even epidemic infections of human sleeping sickness. PMID- 6926765 TI - Reduced pathogenicity associated with a small plaque variant of the Egyptian strain of Rift Valley fever virus (ZH501). AB - Variants of Rift Valley fever virus producing plaques in CER cells of four different sizes are described. A plaque-forming unit (PFU) variant forming minute plaques was isolated and purified. Virus derived from this variant was not pathogenic to adult Swiss albino mice by the intraperitoneal (i.p.) route and was less pathogenic than the parent strain (ZH501) to adult Sprague Dawley rats by i.p. route, but produced typical severe liver necrosis in adult Syrian hamsters with intranuclear and intracytoplasmic eosinophilic inclusions. Antigen and antiserum to the minute variant prepared in mice reciprocally cross-reacted with antisera and antigens of the original strain (ZH501) in the complement fixation test. Plaque size of the minute variant remained constant after serial passages in cell culture and in suckling mouse brain. When the minute plaque variant was passaged i.p. in hamsters, virus which formed large plaques in CER cells was recovered from the hamster sera. PMID- 6926766 TI - A survey of leptospirosis in febrile patients mainly from hospitals and clinics in Trinidad. AB - Acute and convalescent sera were obtained from 202 febrile patients, most of whom were admitted to or attended hospitals or clinics in northern Trinidad during the 12 months from mid-February 1977 to mid-February 1978. Laboratory tests confirmed that 10 of the patients were suffering from current leptospirosis while another 54 had serological evidence of previous leptospiral infections. Antibodies to strains of the Icterohaemorrhagiae serogroup were most commonly found, followed by those to the Hebdomadis and Autumnalis serogroups. Isolates were obtained from the blood of two and the urine of three of the 10 current cases. Four of these strains were identified as belonging to copenhageni serovar of the Icterohaemorrhagiae serogroup and one to serovar brasiliensis of the Bataviae serogroup. Seven of the patients suffering from leptospirosis were males, all rural dwellers, and all except one under 20 years of age. Two of the three female patients were over 60 years old and were urban dwellers. It was not possible to identify the sources of infection with certainty, although dogs may have been responsible for three of the Icterohaemorrhagiae and one of the Canicola infections. Of the 192 patients who were not currently infected, serological evidence of previous infection was obtained in 31 (40%) males and 23 (21%) females and was most common among farmers and rural workers. PMID- 6926768 TI - The distribution of Vibrio parahaemolyticus serotypes in Kenyan seafish, shellfish, marine water and sediment. AB - Vibrio parahaemolyticus was recovered from 74 of 912 marine samples screened for the organism. Of 74 isolates of V. parahaemolyticus obtained from marine fish, crustacean shellfish (prawns, lobster, crabs), and molluscan shellfish (oysters), and from water and sediment collected off the coast of Kenya, only 33 were positively identified. The isolates were only from seafish and shellfish. The main serotypes were 0,3:K37; 0,3:K40; 0,8:39; 0,10:23; 0,10:K52; and 0,11:K40. All the serotypes were Kanagawa-negative. The rest of the samples, mainly marine sediment and water, revealed what was described as untypable Vibrios. This is the first report of the organism in this part of the world where no clinical disease is reported. PMID- 6926769 TI - Thyrotoxicosis in Ethiopian patients--a prospective study. AB - Forty-six cases of thyrotoxicosis, 8 males and 38 females, were seen over a period of two years from March 1979. There were 19 cases of toxic multinodular goitre, 22 of Graves' disease, four of toxic adenoma and one of subacute thyroiditis. The median age of those with toxic multinodular goitre was 49 and of those with Graves' disease was 30 years. The five most common symptoms were sweating/heat intolerance (82.6%), weight loss (82.6%), palpitations (82.6%), nervousness and irritability (73.9%) and insomnia (69.6%). Six of 24 non-pregnant females of child-bearing age had menstrual disturbances. The five most common signs were goitre (97.8%), tachycardia (100.0%), sweating (84.7%), and fine finger and tongue tremors (89.1%). Among the 22 cases of Graves' disease, 13 (59.1%) had exophthalmos and 4 (18.2%) had pretibial myxoedema. Treatment with propylthiouracil or carbimazole was effective in controlling the thyrotoxicosis. Granulocytopenia developed in two cases and skin allergy in one other, necessitating use of alternative treatment. Seven cases had subtotal thyroidectomy after preparation with antithyroid drugs or propranolol and Lugol's iodine. PMID- 6926767 TI - Crithidia fasciculata: a catalase-containing trypanosomatid sensitive to nitroheterocyclic drugs. AB - Crithidia fasciculata, which contains high levels of a cytosolic catalase, is sensitive to inhibition by at least two nitroheterocyclic drugs, Nifurtimox and MK 436, both of which are also active against Trypanosoma cruzi. Drug sensitivity is not enhanced in organisms containing reduced levels of catalase. The ultrastructural lesions in T. cruzi produced by nitroheterocycles, especially the swelling and gross vacuolation of the mitochondria, are seen also in C. fasciculata. These results are not consistent with the hypothesis that the action of drugs such as Nifurtimox on T. cruzi involve hydrogen peroxide accumulation as a result of the absence of catalase. PMID- 6926771 TI - Association of bacteriuria and urinary nitrosamine formation with Schistosoma haematobium infection in the Qalyub area of Egypt. AB - In Egypt, bladder cancer incidence is high in areas where the prevalence and intensity of Schistosoma haematobium infection is also high. Experimental evidence shows bladder carcinogenesis to be a multi-stage process which can be accelerated by many factors. N-nitroso compounds, some of which are known bladder carcinogens, can be formed from amine precursors and nitrate in urine during some bacterial infections. In experimental animals the growth of nitrosamine-induced urothelial cancers is accelerated by damage to the urothelium caused by S. haematobium infections, and by analogy in man this could account for the lower peak age of incidence of this cancer in Egypt by comparison with Europe. The present study was designed to investigate whether bacterial infection of the urinary tract was common in areas of endemic schistosomiasis and whether N nitrosamines were regularly found to be associated with bacteriuria. Urine samples from young men in the Qalyub area of Egypt and from an adjacent Delta region were analysed for S. haematobium ova, the nature and intensity of any bacterial infection, nitrate and nitrite, and total N-nitroso compounds plus volatile N-nitrosamines. A relatively high prevalence of bacteriuria was found in young men with schistosomiasis and low levels of N-nitroso compounds were present in all specimens. When the groups were sub-divided on the basis of the ability of their bacterial flora to reduce nitrate to nitrite (the latter is required for the nitrosation of amine precursors to N-nitroso compounds), significantly higher levels of N-nitroso compounds were found in S. haematobium-infected individuals also infected with nitrate-reducing bacteria by comparison either with uninfected controls (p less than 0.0005) or with those infected with non-nitrate-reducing bacteria (p less than 0.001). The results show N-nitroso compounds to be present in the urines of young men in areas of endemic S. haematobium infection in Egypt, and elevated levels of urinary N-nitroso compounds to be associated with infection of the urinary tract by various species of nitrate-reducing bacteria. PMID- 6926770 TI - Experience with mebendazole in the treatment of inoperable hydatid disease in England. AB - Eleven heterogeneous patients with inoperable hydatid disease were treated with high doses of oral mebendazole, up to 200 mg/kg/day for 16 to 48 weeks. Toxicity was not encountered. Despite careful assessment it proved difficult critically to evaluate the efficacy of mebendazole. In four patients chemotherapy appeared to have been at least partially successful and success seems to have correlated with serum levels in excess of 100 ng/ml one to three hours after dosage. The problems of assessment are discussed and the need for controlled trials of mebendazole in hydatid disease are stressed. PMID- 6926773 TI - Measles immunization in the Zambian copperbelt: cause for concern. PMID- 6926772 TI - Schistosoma mansoni: effects of praziquantel on the ultrastructure of worms in vivo. PMID- 6926774 TI - A review of kala-azar in China from 1949 to 1959. AB - This is the first account of China as an important area of kala-azar to appear in the west for nearly 50 years. The review is divided into four main sections. The epidemiological aspects which are described include the geographical distribution and endemicity (under the sub-headings natural conditions of the epidemic area, age distribution, sex differences, seasonal changes in incidence) and research on reservoirs (under the sub-headings survey of canine leishmaniasis and survey of other wild and domestic animals). The section on clinical aspects covers symptoms and signs, post kala-azar dermal leishmaniasis, laboratory diagnosis (puncture, serum tests, complement fixation test, intradermal test) and treatment (medication and the effects of treatment). The possibility that two different types of kala-azar occur in China is discussed and the paper concludes with an appraisal of the present position. PMID- 6926775 TI - A probable case of ocular angiostrongyliasis in New Britain, Papua New Guinea. AB - Unilateral iritis, keratitis and episcleritis presented in a 45-year-old female Melanesian from New Britain, Papua New Guinea. A motile nematode was seen in the anterior vitreous but was not recovered. Inflammation resolved with topical corticosteroid and antibiotic treatment, but visual impairment persisted. She failed to return for repeat serology after discharge, and measurement of serum antibody levels to Angiostrongylus cantonensis in the single specimen obtained, using the direct and indirect immunofluorescent tests, showed a titre of 1:128. Ocular angiostrongyliasis is briefly reviewed and the differential diagnosis of intra-ocular nematode infestation is presented. PMID- 6926776 TI - Enzyme polymorphism in Trichinella. AB - The isoenzyme profiles of five isolates of the supposed 'species' of Trichinella, T. nativa, T. spiralis and T. nelsoni were compared. Four enzymes (AK, PGM, MPI and GPI) gave good resolution and clearly differentiated T. Spiralis from the other two species. T. nativa and T. nelsoni had similar isoenzyme patterns; the two separate isolates of T. nativa and T. spiralis used gave similar results, thus indicating the validity and the reproducibility of the technique. The value of enzyme electrophoresis for specific and subspecific classification of Trichinella is discussed and compared with the more traditional methods of taxonomy which have failed to resolve the controversy surrounding speciation. PMID- 6926778 TI - Giardia lamblia: incidence in man and dog. PMID- 6926777 TI - Bioavailability and tolerability of mebendazole in patients with inoperable hydatid disease. PMID- 6926779 TI - Canine leishmaniasis in three foci in Western Sicily. PMID- 6926780 TI - Cockroaches and enteric pathogens. PMID- 6926781 TI - Introduction of Biomphalaria glabrata to Egypt and other African countries. PMID- 6926782 TI - Circulating immune complexes in amoebiasis. PMID- 6926786 TI - The pathogenicity and nomenclature of the mycobacteria. PMID- 6926783 TI - Isolation of Mycobacterium simiae from clinical specimens in Israel. AB - Over a period of 7 years (1975-1981), 399 strains of mycobacterium, isolated from 287 persons and one monkey, were identified by a specialized Mycobacterium laboratory as Mycobacterium simiae. About 93% of isolates were from sputum or laryngeal swabs. All persons but one (181 males and 106 females) resided in the coastal plain, mainly the Tel Aviv area. From 240 single isolations were obtained, from 29 there were 2 isolations and from 18 there were 3 or more isolations. The 18 cases with multiple isolations are presented and discussed. PMID- 6926785 TI - Clinical aspects of leprosy. PMID- 6926784 TI - Adverse effects of antituberculosis drugs causing changes in treatment. AB - The adverse effects of drugs which caused changes in therapeutic regimens have been studied in 511 patients with pulmonary tuberculosis, at the Pavilion Koch of Buenos Aires University. In 384 patients who had not received any treatment before, the frequency of such modifications was 6.5%, and in 127 retreated patients it was 15.0%. The characteristics of the adverse effects and the measures aimed at reducing them were studied. PMID- 6926788 TI - Incidence of alpha-thalassemia in Turkey. PMID- 6926787 TI - The significance of zinc, copper and magnesium levels of maternal, cord and newborns' sera in hyperbilirubinemia of unknown etiology. PMID- 6926789 TI - Fetal malnutrition in infants born to diabetic mothers. PMID- 6926790 TI - Congenital left coronary artery--right ventricle fistula. PMID- 6926791 TI - Supravalvular aortic stenosis. PMID- 6926792 TI - Soft tissue calcification in chronic renal failure in childhood. PMID- 6926793 TI - Symptomatic hypocalcemia and hypomagnesemia due to gentamicin therapy in an 8 year-old girl. PMID- 6926794 TI - Hemoglobin Koln [beta 98 (FG5) Val-Met] in a Turkish child. PMID- 6926795 TI - [Mycotic esophagitis]. PMID- 6926797 TI - [Crohn disease in Tunisia]. PMID- 6926798 TI - [A case of Crabbe and Hermans disease]. PMID- 6926796 TI - [Gastric polyposis in familial rectocolonic polyposis]. PMID- 6926799 TI - [Primary immune deficiency and malabsorption. Report of 4 cases]. PMID- 6926800 TI - [Peutz-Jeghers syndrome]. PMID- 6926802 TI - [Double gallbladders]. PMID- 6926801 TI - [25 cases of non-traumatic perforation of the small intestine]. PMID- 6926803 TI - [Role of endoscopic treatment in residual lithiasis]. PMID- 6926804 TI - [Endoscopic retrograde cholangiopancreatography and pancreatic diseases]. PMID- 6926805 TI - [Primary cancer of the liver in the adult. Study apropos of 16 cases]. PMID- 6926806 TI - [Emission of organic substances from chip-boards]. AB - A relatively small number of investigations on emissions of organic substances from chip-board is available up to now. The emissions known to date are caused by glues or other additives rather than by the wood itself. As concerns aminoplast glues (urea-formaldehyde or melamine-formaldehyde resins) the most important point of public interest has been the off-gassing of formaldehyde from chip board. Chip-board with phenol-formaldehyde glues has been known in some cases to give off phenol. The formation of diamino diphenyl methane from isocyanate glues is still a matter of discussion. A further source for possible emissions are wood and fire protectives which are added during the manufacturing process. Finally, coating of chip-board may lead to emissions of organic substances. The lack of adequate detection methods has so far delayed the treatment of questions in relation to emissions from chip-board. Even now, there are numerous problems in this field especially when investigating isocyanate glues. Problems in relation to the origin of emissions due to the kind of glue used and the manufacturing process are discussed, and proposals are made how to solve some of these problems. The question of the health risk is dealt with from the view-point of the civil engineer and in an general economic context. PMID- 6926807 TI - IgG and IgM rheumatoid factor in active seronegative nodular rheumatoid arthritis and in children with benign rheumatoid nodules. PMID- 6926808 TI - Prognosis of functional capacity and work capacity in rheumatoid arthritis. AB - In the study functional capacity and work capacity were investigated in a series of 405 hospital patients suffering from rheumatoid arthritis. One-third of the patients had had the disease for 5 years, one-third for 10 years and one-third for 15 years. The functional capacity index presented by Lee et al. (1973) was used. Half of the patients in the 5 and 10-year groups and one-third of those in the 15-year group had good functional capacity. One-fourth in the 5 and 10-year groups and one-third of those in the 15-year group had poor functional capacity. Sixty per cent of the 5-year group, 50 per cent of the 10-year group and 33 per cent of the 15-year group were able to work. The prognosis of functional capacity and work capacity was better for young persons than for older ones. No differences were found between the prognoses for men and women. High ESR, a positive blood rheumatoid factor and joint erosion seemed to be linked with an unfavourable prognosis of functional capacity. Light work was favoured for the prognosis of functional capacity and work capacity and extensive general education and vocational training for work capacity. The results indicate that starting vocational rehabilitation at an early stage of the disease could improve the prognosis of functional capacity and work capacity. PMID- 6926809 TI - Rheumatoid lymphoedema. AB - Bilateral upper limb oedema due to lymphatic obstruction, is an uncommon complication of rheumatoid arthritis (R. A.). We report a case in which a 40 year old male with seropositive rheumatoid arthritis developed gross pitting oedema of the left arm. Lymphangiography showed lymphatic obstruction in both arms; within two months the right arm also became oedematous. PMID- 6926810 TI - Mixed connective tissue disease: some statements. PMID- 6926811 TI - Osteonecrosis of the femoral head and pregnancy. AB - The authors report 7 anatomo-clinical cases of osteonecrosis of the femoral head, the clinical onset of which occurred during pregnancy or in the fortnight after delivery. On the basis of histological data obtained through core-biopsy in these 7 cases they discuss the relationship between osteonecrosis and reflex sympathetic dystrophy of the hip. PMID- 6926812 TI - Effects of 3-methylcholanthrene and DDT on cholesterol 7 alpha-hydroxylase in rats. AB - The possibility that cholesterol 7 alpha-hydroxylase activity and cholesterol metabolism could be mediated by chemical inducers of the microsomal mixed function oxidase (MFO) system was investigated. Groups of male Wistar rats weighing about 250 gm were treated with the inducer compounds, DDT, phenobarbital, or 3-methylcholanthrene, or with the hypocholesterolemic drugs, D thyroxine, clofibrate, or with pharmacological doses of nicotinic acid. Although clofibrate and nicotinic acid produced some increases in MFO activity as reflected in p-nitroanisole-o-demethylase and aniline hydroxylase, no change in the activity of cholesterol 7 alpha-hydroxylase was produced by the hypocholesterolemic drugs. The inducer compounds produced typical responses of increased liver weight, microsomal protein, and p-nitroanisole-o-demethylase, and aniline hydroxylase activities. 3-Methylcholanthrene and DDT, however, both caused a significant decrease in cholesterol 7 alpha-hydroxylase activity. 3 Methylcholanthrene, which produced the greatest decrease in cholesterol 7 alpha hydroxylase activity, also caused a marked elevation in serum cholesterol levels. It seems plausible that the decrease in cholesterol 7 alpha-hydroxylase produced by 3-methylcholanthrene may have produced the elevation in serum cholesterol levels. PMID- 6926813 TI - Ethanol and diet interactions in male rhesus monkeys. AB - Development of alcohol-related liver and other diseases appears to be modified by host and environmental factors that include diet and nutritional status, exposure to other drugs and toxins, and infection. The relative importance of alcohol toxicity and malnutrition in the induction of fatty liver and cirrhosis, the subject of this report, has been debated. Male rhesus (M mulatta) monkeys were fed purified liquid diets, adequate or marginally deficient in lipotropes (choline, methionine, and folate), containing ethanol to supply 40-50% of calories for 1.5-4.5 years. Controls, fed the diets with sucrose and fat isocalorically substituted for ethanol, grew well and were clinically normal. Ethanol-fed monkeys in both diet groups failed to gain weight and were slightly anemic, with mild derangements of serum electrolytes and small amounts of fat in their livers. None had fibrosis or cirrhosis until the severity of the lipotrope deficiency was increased; then two of four deficient animals developed cirrhosis and one developed fibrosis. (The severe deficiency induced weight loss and fatty liver, but not fibrosis, in one of two controls.) We conclude that alcohol does not induce hepatic fibrosis or cirrhosis in rhesus monkeys fed a nutritionally complete diet, a result supported by studies in rats and another monkey, M radiata. Alcohol does induce cirrhosis when fed in combination with a lipotrope deficient diet that is not, by itself, cirrhogenic. PMID- 6926815 TI - Inhibition of 5-methyltetrahydrofolic acid transport by amphipathic drugs. AB - Numerous chemically unrelated drugs after the membrane transport of folate compounds. To investigate drug structure-activity relationships, we measured the effect of amphipathic drugs (that is, compounds with polar-apolar character) on 5 methyltetrahydrofolic acid permeability of human erythrocytes. All drugs tested were inhibitory, but only compounds that exist at least partially in the anionic form were highly active. Ethacrynic acid, sulfinpyrazone, phenylbutazone, sulfasalazine, and furosemide were effective transport inhibitors in micromolar concentrations. In contrast, compounds that are capable of forming cations at physiologic pH, such as chlorpromazine, procaine, tetracaine, and papaverine, were inhibitory only in millimolar concentrations or caused hemolysis before major inhibition was seen. Inhibitory activity correlated with drug dissociation constant (r = 0.87). A double-reciprocal plot analysis of drug effect on 5 methyltetrahydrofolic acid transport showed changes in both Km and Vmax (indicating a mixture of competitive and noncompetitive inhibition) by ethacrynic acid, sulfasalazine, and phlorizin. Inhibitory activity of a series of eight phenoxyacetic derivatives, including ethacrynic acid, correlated highly with measurements of liposolubility (r = 0.87) but only weakly with the Hammet substituent constant (r = 0.56). These results suggest that the effect of amphipathic drugs on 5-methyltetrahydrofolic acid transport is influenced by drug pKa and by the presence of hydrophobic substituents, but is relatively independent of electron-attracting groups. PMID- 6926814 TI - Effect of dietary lipid on benzo(a)pyrene metabolism by perfused rat liver. AB - Male Holtzman albino rats weighing 60-75 gm were fed purified synthetic diets containing casein (18%), alphacel (4%), wheat starch (44%), sucrose (26%), Jones Foster salt mix (4%), and vitamin mix (4%) for three weeks. The diet for group I contained no fat, whereas corn oil (10%) substituted for 10% sucrose in the diet for group II. All animals were administered 3-methylcholanthrene [20 mg/kg intraperitoneally (ip) in 0.5% methylcellulose solution] for two successive days prior to sacrifice in order to increase the activity of the mixed function oxidase (MFO) responsible for metabolizing benzo(a)pyrene [B(a)P]. After 21 days on diet, livers were perfused with benzo(a)pyrene in blood-free Krebs Henseleit bicarbonate buffer containing 100 mg glucose plus 200 units of heparin per 100 ml. Aliquots of perfusate were removed at five, ten, 20, 30, 40, and 60 minutes for analysis of B(a)P metabolites. Higher concentrations of B(a)P-9, 10 dihydrodiol; B(a)P-4,5-dihydrodiol; B(a)P-7,8-dihydrodiol; and 3-hydroxy B(a)P were recovered from livers of rats fed the diet containing 10% corn oil than from livers of rats fed the fat-free diet. The concentrations of 9-hydroxy B(a)P except the 9,10-dihydrodiol were recovered from bile along with two unidentified metabolites. Following the perfusion period, homogenized and extracted livers from rats fed the diet containing corn oil retained significantly higher concentration of the three dihydrodiols and two phenols than livers from rats fed the fat-free diet. PMID- 6926816 TI - Effects of high dietary vitamin A on drug-metabolizing enzyme activities in guinea pig and rabbit. AB - The effect of high dietary Vitamin A on drug-metabolizing enzyme activities was studied in the guinea pig and rabbit. The guinea pigs and rabbits were given a high vitamin A test diet for six and seven weeks, respectively. The control groups received the diets containing normal amounts of vitamin A. The feeding of the high vitamin A diet increased the activities of aminopyrine demethylase and aniline hydroxylase in the guinea pig liver but not in the rabbit liver. The 7 ethoxycoumarin deethylase activities were increased in the rabbit liver but not in the guinea pig liver. The aminopyrine demethylase and aniline hydroxylase activities were lowered in both lung and intestine of rabbit. The benzpyrene hydroxylase activities were lowered only in rabbit lung. In general, these results suggest that the effect of a high vitamin A in diet on drug-metabolizing enzymes depends on the animal species, type of tissue, and substrate used. PMID- 6926817 TI - Dietary fat and 3-MC induction of hepatic nuclear and microsomal cytochrome P 450. AB - Hepatic microsomes from male Holtzman albino rats fed a synthetic fat-free diet for 21 days had significantly less cytochrome P-450 and exhibited less binding capacity (delta Amax/mg protein) for aniline and octylamine than microsomes from similar rats fed a diet containing 10% corn oil. Treatment with 3 methylcholanthrene (3-MC) increased the concentrations of cytochrome P-450 (as measured by CO binding spectra) to nearly equal levels in both dietary groups, but the binding of aniline and octylamine to microsomes of rats fed the fat diet exceeded the increase in cytochrome P-450 concentration. Nuclear envelope concentrations of cytochrome P-450 were unaffected by diet. The administration of 3-MC to rats fed a fat-free diet failed to induce nuclear envelope P-450; however, in rats fed the corn oil diet, 3-MC increased this CO binding pigment over twofold. The affinity of nuclear envelope P-450 towards type II substrates was at least equal to that of microsomes, except in control rats fed the fat-free diet. In general, 3-MC pretreatment increased the binding affinity of nuclear envelop and microsomes toward aniline, while increasing affinity for SKF 525-A binding only to nuclear envelope. Molecular weight species in the region known to contain the cytochrome P-450 were quantified by fluorescence gel electrophoresis. Molecular weight species of 48,000 and 53,000 in the nuclear envelope had their counterparts in the microsomal preparation, but a 50,000 dalton component of nuclear envelope was not detected in microsomes. 3-Methylcholanthrene increased only a species with molecular weight 45,500 in the microsomal and nuclear envelope preparations. Rats fed the diet containing corn oil had microsomes with increased capacity for binding CO, but this was not accompanied by increased cytochrome P-450 protein concentration, as measured by quantitative fluorescence gel electrophoresis. PMID- 6926818 TI - Influence of food on the absorption of hydrocortisone from the gastrointestinal tract. AB - Plasma levels of hydrocortisone were examined following single 60-mg oral doses to healthy male and female volunteers. The doses were administered following an overnight fast with 20 ml or 250 ml of water, or immediately following a standard breakfast. Plasma hydrocortisone levels in individual subjects were adequately described by a simple one-compartment kinetic model incorporating first-order drug absorption and elimination, and an absorption lag-time. The The absorption of hydrocortisone was delayed following the nonfasting treatment, compared to the fasting treatments. Peak drug levels in plasma were significantly reduced, and the time taken to achieve these levels was significantly increased when the hydrocortisone was ingested after food. In order to optimize the consistency of patient response to oral hydrocortisone therapy, the drug should be administered routinely on a fasted stomach. PMID- 6926819 TI - Alteration of thyroid hormone economy during alcohol withdrawal in alcoholics. AB - Alcohol and alcohol withdrawal may affect nutritional status in many different ways, including effects on thyroid activity. The influence of alcohol withdrawal on thyroid hormone economy was investigated by measurements of changes in the serum concentrations of thyroxine (T4), 3, 5, 3'-triiodothyronine (T3), 3, 5, 5' triiodothyronine (reverse T3, rT3), and thyrotropin (TSH) in chronic alcoholics experiencing different degrees of alcohol abstinence. In addition, the serum concentrations of ethanol were measured at entrance. There was no significant correlation between the entrance serum ethanol levels, on the one hand, and those of T4, T3, rT3, or TSH, on the other. However, during severe ethanol abstinence (with or without delirium tremens), there was a significant increase in the serum levels of T4 and rT3, but not in those of T3 and TSH. These findings indicate that (severe) alcohol abstinence can interfere with thyroid hormone economy, either by enhancing thyroid hormone secretion or by reducing T4 and rT3 deiodination. It is an open question whether this represents a beneficial adaptation to the metabolic disturbance caused by alcohol intoxication and abstinence, or an additional derangement that warrants nutritional or other therapeutic measures. PMID- 6926820 TI - Discrimination of sucrose-taste by the rat as a potential bioassay for sweeteners. AB - Male hooded rats were trained to discriminate the taste of a sucrose solution from that of water by responding with a lever on one side of a food cup after 20 licks (500 microliter) a 0. M sucrose solution and responding with a lever on the alternating side after 20 licks of water for food reinforcement. All of the rats learned this discrimination reliably. The gustatory stimulus produced by sucrose was concentration dependent (EC50 = 1.3 X 10(-2) M). Saccharin (0.0002-0.002 M), dextrose (0.05-0.25 M), and glycine (0.002-0.2 M) produced a concentration dependent generalization to the sucrose taste. The EC50 values were 1 X 10(-3), 2.7 X 10(-2), and 1.3 X 10(-1) M, respectively. Solutions of sodium chloride (0.15 M), citric acid (0.01 M), caffeine citrate (0.01 M), quinine hydrochloride (0.001 M), or l-amphetamine sulfate (0.05 M) did not produce sucrose-like taste. Generalization of sweet compounds and lack of generalization of other tastes to the sucrose taste suggest that the procedure of sucrose-water discrimination by the rat has potential in the detection and quantitation of the sweetening properties of new chemicals. PMID- 6926822 TI - Effect of lead acetate on rats fed diets containing low levels of folic acid. AB - Nutritional factors such as deficiencies of calcium, iron, and protein alter susceptibility to the toxic effects of lead. While the suggestion has been made that vitamins may also influence lead toxicity, possible interactions have not been well documented. The present studies were performed to determine if a dietary deficiency of folic acid enhances the susceptibility to rats of the toxic effects of lead acetate. Lead exposure during the development of folate deficiency resulted in alterations in two of the parameters diagnostic of the individual conditions. Decreases in erythrocyte mean corpuscular volume (MCV) occur during lead poisoning, while increases occur during the development of folate deficiency. In the present study, significant reductions in MCV were observed in both the control + lead and in the low folate + lead groups. The increased MCV characteristic of folate deficiency was prevented by the concomitant lead exposure. Elevations in free erythrocyte protoporphyrin (FEP) levels are characteristic of lead intoxication; in contrast, FEP levels decline during folate deficiency. In the present study, FEP levels were significantly elevated only in the control + lead group. Values in the low folate + lead group were intermediate between those of the control and the control + lead groups, but did not differ significantly from those in the low folate group. The expected lead-induced elevation in FEP levels was diminished by the reduced erythropoiesis characteristic of folate deficiency. PMID- 6926821 TI - Choline availability: effects on the toxicity of centrally active drugs. AB - The effect of chronic choline supplementation was studied on the toxicity of various pharmacological agents in rats and mice. Choline prevented both the incidence of seizures and the consequent lethality of nicotine, paraoxon, pentylenetetrazol, and strychnine. Nicotine toxicity was most markedly affected, and the prophylactic effects of choline were present in both rats and mice following either dietary or parenteral supplementation. Results suggest that chronic choline availability may alter neuronal membrane excitability. PMID- 6926823 TI - Modification of circadian rhythms of drug metabolism in the Syrian hamster. AB - Male Syrian hamsters consumed one of three levels of lactalbumin (10, 20, or 40%) for 8 weeks prior to administration of a single dose of 20 mg/kg (sc) N nitrosobis(2-oxopropyl)amine (BOP) at 0600 hr. Liver weights, liver microsomal protein, and cytochrome P450 content and the activities of microsomal ethylmorphine N-demethylase (EMND), aniline hydroxylase (ANH), and arylhydrocarbon hydroxylase (AHH) were determined in control and BOP-treated animals after 0 (0600), 3 (0900), 6 (1200), 12 (1800), and 24 (0600) hr. Circadian rhythms were observed in liver weights, contents of microsomal protein, and cytochrome P450 and in the activities of EMND and ANH. Cycles of liver weight, cytochrome P450, and EMND activity were present in animals fed the higher (20 and 40%) lactalbumin levels, but not in those fed the low level (10%). BOP treatment eliminated the circadian cycles of cytochrome P450 and EMND, and reduced liver weight, the content of microsomal protein, and the ANH activity at two or three of the measurement times. AHH activity did not exhibit a circadian cycle, but these values were consistently increased by feeding high protein and reduced by BOP. PMID- 6926824 TI - Relative contribution of diet and biosynthesis to the taurine content of the adult rat. AB - The relative contribution of diet and biosynthesis to the taurine content of the rat has been determined quantitatively under various dietary conditions. Rats were maintained on diets containing [3H]taurine and/or [35S]methionine of known amounts and specific activities, and subsequently the specific activity of taurine in various tissues was determined. This approach gives a quantitative measure of how much taurine is biosynthesized versus how much is derived from the diet regardless of the biosynthetic route or site of biosynthesis in the animal. With no taurine in the diet, over an 87-day period, 54% of the taurine in the animal had been biosynthesized. This fell to 29% if taurine was present in the diet, and the contribution of dietary taurine to body pools rose to 58%. These changes in biosynthetic contributions were not accompanied by an alteration in the rate of biosynthesis but by an alteration in rate of excretion. When the amounts of biosynthesized taurine appearing in the urine over 63 days was added to the amounts found in the carcass, 3.1 mmol were found to be biosynthesized by animals receiving taurine in the diet as compared to 2.9 mmol in animals on a taurine-deficient diet. In any one experiment, the contribution of diet or biosynthesis is invariant from tissue to tissue indicating that the rate of exchange of taurine between tissues is faster than the rate of elimination of taurine from the body. PMID- 6926825 TI - An effect of sulfur nutrition on the metabolism of salicylamide. AB - The effect of supplementing diets containing 15% casein with inorganic sulfate and/or the sulfur-containing amino acids on the metabolism of salicylamide was determined. The glucuronide-salicylamide:sulfate-salicylamide (GS:SS) ratio in the urine of rats fed the diets containing 15% of casein without inorganic sulfate or sulfur containing amino acid supplementation approached unity. Addition of either 0.02% of inorganic sulfate or 0.625% of methionine reduced this ratio to approximately 0.3%. Addition of 0.325% of methionine or sufficient cysteine to be equimolar with 0.625% methionine did not lower the GS:SS ratio significantly. Therefore, it appears that not only the level but the source of sulfur may be important in the detoxication of drugs. PMID- 6926826 TI - Dietary amino acids and hepatic microsomal drug metabolism in Syrian hamsters. AB - The source and level of amino acids fed to Syrian hamsters modified hepatic microsomal drug metabolism in this species, and the effects differed between the two sexes. Drug-metabolism systems of the liver were evaluated in Syrian golden hamsters fed three sources of amino acids, casein (C), lactalbumin (L) and supplemented casein (SC), each at four levels (4, 10, 20, and 40 gm/100 gm of diet). A protein-free (PF) diet was fed to an additional hamster group. Hepatic microsomal protein content, cytochrome P450 content, and aryl hydrocarbon hydroxylase (AHH) and aniline hydroxylase (ANH) activities were measured after three weeks of feeding the diets. Microsomal protein content generally rose with increasing protein levels in the diets from 0 to 20 gm/100 gm diet, except for C fed females, in which values did not differ from those fed PF diet. Supplemented casein supported no increased levels of microsomal protein when fed from 4-40 gm/100 gm diet; however microsomal protein rose from increased dietary C and L up to 20 gm/100 gm diet in males and from increased L up to 20 mg/100 gm diet in females. Cytochrome P450 content was influenced in animals fed C and L by amino acid level in a manner similar to observed effects on microsomal protein. However, consumption of 10 gm SC/100 gm diet by males resulted in the highest cytochrome levels. AHH activity rose with increased dietary amino acids for both male and female hamsters; and maximal activities occurred in hamsters fed the 20 or 40 gm protein/100 gm diet levels. ANH activity was influenced both by amino acid source and level with both sexes; the feeding of C resulted in a higher activity of this enzyme than that of SC. ANH activity was highest in hamsters fed the 20 and 40 gm amino acid/100 gm diet levels. PMID- 6926827 TI - Long-term effects of partially hydrogenated herring oil on the rat myocardium. AB - Male Sprague-Dawley rats were fed semisynthetic diets containing 25% (w/w) experimental lipid. A partially hydrogenated herring oil (PHHO), containing 25% C22:1 as an isomeric mixture dominated by cetoleic (cis-docos-11-enoic), but partially altered to the trans form and containing other positional isomers, was compared with lard:corn oil 3:1(LCO) (w/w). The feeding period extended up to 111 weeks. Ten animals from both groups each were sacrificed at 2, 8, 16, 24, and 32 weeks. The remaining animals from each group were kept on the diets either until spontaneous death occurred or until Week 111. The LCO rats had higher serum cholesterol levels. The PHHO rats had transient myocardial lipidosis and very severe, progressive myocardial inflammation and scarring. PMID- 6926830 TI - Dietary influence on caecal microbial nitroreduction of a drug: metronidazole. AB - Six diets were fed to weanling rats and the in vitro caecal microbial nitroreduction rates of metronidazole were determined. The sensitivity of this metabolic pathway to diet was demonstrated by the observed 20-fold range in reaction rate constant. Methods were devised to investigate the mechanism of this dietary effect. It was concluded that indigestible dietary components affected primarily both the weight of caecal contents and the metabolic activities of the microorganisms per unit weight of caecal contents. It appeared that the actual reaction rate in the caecum might be 35% higher than that determined by the standard assay procedure that involves sample dilution. However, the different soluble materials in the caeca derived from rats fed different diets had no significant secondary regulatory effects on the rate constant. PMID- 6926829 TI - The effect of dietary fortification on blood ethanol concentrations, caloric consumption, and weight gain during ethanol consumption in mice. AB - The objectives of this study were to determine the effects of dietary fortification on caloric consumption, weight gain, and blood ethanol concentration (BEC) in mice consuming ethanol-containing liquid diets. These diets have been used previously in this laboratory for ethanol fetotoxicity studies. To achieve these objectives, mice were adapted to a commonly used liquid mouse diet and randomly allocated to one of two experimental groups. One group received the liquid diet containing 4.1% (w/v) ethanol. The second group received the 4.1% w/v ethanol diet fortified with protein, carbohydrates, fats, vitamins, and minerals. Animals in both groups were monitored for weight changes and caloric intake. On days 5 and 12 of exposure (day 0- initial day), animals were sampled for BEC at 3-hour time intervals throughout a 24-hour period. All animals not previously sampled for BEC were also monitored every 3 hours for dietary intake. The animals receiving the fortified diet had a greater caloric consumption and weight gain during the 13 days of treatment than did the nonfortified diet animals. Blood ethanol levels determined on both sample days were significantly lower in the fortified diet group than in the nonfortified group. BEC values in both groups were significantly correlated with ethanol consumption during the previous 6-hour period. In conclusion, dietary modification could significantly alter the outcome of ethanol toxicity studies both by direct effects on growth and caloric/nutrient intake and by altering blood ethanol levels achieved during exposure. PMID- 6926828 TI - Hepatic bromobenzene epoxidation and binding: prevention by ascorbyl palmitate. AB - Bromobenzene undergoes metabolic activation via 2,3- and 3,4-epoxidation catalyzed by the hepatic cytochrome P-450 mixed-function oxidase system. Its reactive metabolites, especially bromobenzene 3,4-oxide, presumably lead to severe centrolobular necrosis. A study of relative rate of binding of 14C bromobenzene metabolites to hepatic microsomal protein indicated a significant difference in the rate of binding of the bromobenzene 3,4-oxide compared to its positional isomer, bromobenzene 2,3-oxide. However, the rate of bromobenzene metabolism indicated no significant difference in the formation of products o bromophenol and p-bromophenol. A search for protective agents revealed that 6,7 dimethyl-5,6,7,8-tetrahydropterine and ascorbyl palmitate were very effective in protecting against macromolecular adduct formation at a concentration of 1 mM-in fact, at least a twofold increase in protection compared to the known protective agents such as glutathione or cysteine. Furthermore, 6,7-dimethyl-5,6,7,8 tetrahydropterine and ascorbyl palmitate inhibited the metabolism of bromobenzene over 90% at a concentration of 2.5 mM. PMID- 6926831 TI - Alteration of toxicity to paraquat in mice fed a purified or cereal-based diet. AB - Toxicity to several compounds is affected by dietary changes that by themselves do not result in nutrient deficiency or toxicity. The herbicide paraquat was tested to determine whether feeding a cereal-based closed formula diet or a purified diet would affect the sensitivity of mice to paraquat. After an intraperitoneal injection of paraquat, 28-day-old male ICR mice, which had been fed a purified diet for periods of 3 to 84 days, had shorter survival times and lower 7-day percent survivals than mice fed a cereal-base closed formula diet. The median lethal dose of paraquat was significantly lower in mice fed the purified diet rather than the closed formula diet. Median effective time to death was also significantly shorter for male ICR mice fed the purified diet rather than the closed formula diet. Female ICR mice and male B6C3F1 mice fed the purified diet for 7 days were more susceptible to paraquat toxicity than similar mice fed the closed formula diet. Male C57BL/6J mice were more sensitive to the effects of paraquat regardless of the type of diet. Modifying the content of lipid, vitamin E, or selenium, or adding butylated hydroxytoluene to the purified diet did not prevent a decrease in 7-day percent survival and survival time compared to male ICR mice fed a closed formula diet. Male ICR mice fed the purified diet with egg-white protein had significantly longer survival times compared to mice fed the purified diet with casein. It is concluded that strictly defined diets must be used in the study of paraquat toxicity to control for any paraquat-diet interactions. PMID- 6926832 TI - Thyroid status alters structure of VLDL secreted by perfused rat liver. AB - The interaction of thyroid status and oleic acid infusion rate on the thermal behavior of the very low density lipoprotein (VLDL) secreted by isolated perfused rat liver was examined. The livers were infused at 37 degrees C with oleate at rates of 0, 83, 166, or 332 mumoles/hr for 4 hours and VLDL was isolated from the perfusate at 12 degrees C. The lipid composition of the VLDL secreted by the perfused liver from hyperthyroid animals was dramatically different from controls at all infusion rates of oleate. Significant changes in the ratio of [phospholipid + cholesterol]/[triglyceride] and in fatty composition of secreted triglycerides occurred. Differential scanning calorimetry of the intact VLDL and extracted triglycerides secreted by euthyroid rats suggested the existence of four thermotropic endothermic transitions centered at -20.5, -14.0, -3.0, and 9.0 degrees C. Both the total enthalpies and the temperatures at which the phase alterations occurred in the triglyceride fraction from VLDL secreted by livers from euthyroid rats were highly dependent on the rate of infusion of oleate. Pretreatment of the rats with triiodothyronine and infusion of 332 mumoles oleate/hr abolished in the intact VLDL the temperature transitions centered at 20.8 and at 10.5 degrees C and decreased the total enthalpy from 8.13 to 38.5 cal/gm. Livers from rats pretreated with propylthiouracil and infused with oleate at 332 mumoles/hr secreted VLDL in which only one transition centered at -5.0 degrees C remained. The total enthalpy was unaffected. At all rates of infusion of oleate, the phase behavior of the intact VLDL or triglycerides extracted from the VLDL was altered by prior treatment of the rats with triiodothyronine or propylthiouracil. The thyroid state of the rat profoundly affected the thermal properties of the VLDL secreted by the perfused liver infused with the unsaturated fatty acid oleate. PMID- 6926834 TI - Methotrexate effects on hepatic betaine levels in choline-supplemented and choline-deficient rats. AB - Groups of rats fed both choline-supplemented and choline-deficient diets were injected with methotrexate (MTX) at dose levels of 0.1 mg/kg/day and 0.2 mg/kg/day. Both doses produced lowered hepatic betaine levels in the choline supplemented animals when compared with nontreated, pair-fed controls. Since betaine levels were very low in the livers of choline-deficient rats, MTX had no further effect on hepatic betaine in these animals. These data suggest that the betaine lowering seen in livers of choline-fed rats may be due to utilization as a means of compensating for the MTX-induced loss of N5 methyltetrahydrofolate for the vital methylation of homocysteine in methionine biosynthesis. PMID- 6926833 TI - The protective effect of hymochromone against ethanol-induced thiamin deficiency. AB - Intragastric administration of ethanol to male rats given at 6 gm/kg body weight, daily for two weeks, produced no significant change in the body or liver weights. Hepatic total lipid increased but this was no more than a trend. Treatment with ethanol, however, resulted in a marked decrease in transketolase activity (TK) of the haemolysed whole blood, associated with a pronounced rise in the stimulating effect of thiamin pyrophosphate on this enzyme (TPP effect). These changes mediated by ethanol were counteracted by hymochromone. PMID- 6926836 TI - Influence of food on the bioavailability of "real" and "apparent" hydralazine from conventional and slow-release preparations. AB - The influence of concomitant food intake on the bioavailability of hydralazine was studied in healthy volunteers following single-dose administrations in the fasting state and together with a standardized breakfast meal of 1840 kJ (440 kcal). Both "real" (presumably active) and "apparent" (= total = "real" hydralazine + acid-labile hydrazones formed after hydralazine ingestion) hydralazine were determined by gas chromatography. Concomitant food intake seemed to enhance the bioavailability of both "apparent" and "real" hydralazine following ingestion of conventional hydralazine tablets. On the other hand, food intake did not significantly affect hydralazine bioavailability from a slow release preparation. The enhanced effect of food on hydralazine bioavailability from the conventional preparation is probably due to reduced first-pass metabolism. PMID- 6926837 TI - The effect of methotrexate on homocysteine methylating agents in rat liver. AB - Methotrexate (MTX) was administered to rats in a time course study throughout a 4 month period. Despite an inhibition of the hepatic dihydrofolate reductase by 88 to 90% in these animals, the body weights and liver weights of the treated animals did not vary from those of the pair-fed controls during this time course, and the livers showed no fatty infiltration as demonstrated by triglyceride analyses. The prime methylating agent of homocysteine, N5 methyltetrahydrofolate, progressively increased in control livers throughout the experimental period; however, MTX impaired the increases at the 2- and 4-month periods in the treated animals. Hepatic betaine, the secondary methylator of homocysteine in the liver, also increased in the controls during the experimental period. These increases were also impaired in the MTX-treated animals. These data suggest that betaine may compensate for N5 methyltetrahydrofolate as a methylating substance when folate metabolism is antagonized in rat liver. PMID- 6926835 TI - Dietary cholesterol-induced changes of xenobiotic metabolism in liver. I. Influence of xenobiotic administration on hepatic membrane structure. AB - We have studied the effects of dietary lipids on the structure and function of hepatic endoplasmic reticulum by feeding rats either with a 2% cholesterol or cholesterol-free diet. Rats were further administered either phenobarbitone, carbon tetrachloride, or both in combination to reveal possible differences in the response of the microsomal membranes to xenobiotics. Cholesterol feeding increased the membrane cholesterol contents and also carbon tetrachloride increased microsomal cholesterol contents in those rats fed a cholesterol-free diet. Also the microsomal phospholipid contents were higher in those rats fed 2% cholesterol diet than in those fed cholesterol-free diet and in the 2% cholesterol group also phenobarbitone increased the phospholipid contents. In addition, there were changes in the phospholipid-fatty acid proportions between rats fed 2% cholesterol and cholesterol-free diets. When 1,8-ANS was used as a fluorescence probe, phenobarbitone increased the fluorescence in both the dietary groups, while carbon tetrachloride decreased it; less change was present using PNA as a substrate. When Scatchard plots were constructed phenobarbitone changed the turning point more in the cholesterol-free group than in the 2% cholesterol group, while reversed orders of changes were found with carbon tetrachloride. The results demonstrated that dietary cholesterol has profound effects on the structure of microsomal membranes far beyond changes in their cholesterol content. The membrane fluidity also changes owing to alterations in the phospholipid contents and in their fatty acid composition. PMID- 6926838 TI - Influence of food and of age on nitrazepam kinetics. AB - The influence of food intake and of age on the kinetics of nitrazepam was examined in eight young and eight elderly healthy volunteers after single-dose administration of the drug. Serial blood samples were obtained during 0-24 hr, and the serum concentrations of nitrazepam were determined by gas chromatography. Concomitant food intake had no apparent influence on the absorption rate or on the bioavailability of nitrazepam in the young subjects, and there was no significant difference in nitrazepam kinetics between young and elderly subjects. Accordingly, nitrazepam may be taken together with food as well as on an empty stomach, at least in young subjects, and the increased nitrazepam sensitivity often seen in elderly subjects does not seem secondary to age-dependent pharmacokinetic differences. PMID- 6926840 TI - Patterns of cardiovascular diseases mortality in the Glasgow region. AB - In a region of high mortality from cardiovascular diseases questions are posed on the spatial uniformity and temporal consistency of the mortality pattern. Cardiovascular diseases in the Glasgow region of Scotland were examined in response to these questions. Between 1964 and 1972 inclusive, extensive and significant variations from the regional mean were found for cardiovascular diseases mortality in local areas of the study region. Local areas south-east of Glasgow (in Lanarkshire) highlighted localities with above average mortality. Elsewhere, several local areas in Ayrshire, southwest of Glasgow, had high mortality. The main location where mortality was below average occurred to the west of the centre of the region. The need for further analysis of temporal characteristics and an examination of the association between disease rates and other environmental indicators is suggested by the findings. PMID- 6926841 TI - Influenza-like illness: a monitoring system. AB - This paper draws attention to the widespread problems associated with an epidemic of influenza at all levels--personal, family and society. In the absence of effective policies of prevention and cure, there is a need for a system which will constantly survey the scene on a clinical basis and give an early warning of an impending epidemic. The means hitherto available have been crude and rather slow to react. A system is described which is based on weekly telephoned reports from a geographically widely spread network of general practitioners, mainly in Tayside. The co-ordinated system operates during the influenza 'season', and provides information to the contributors, health planners, epidemiologists and to WHO. Examples of the work of the 'spotter practices' are drawn from the season 1980-81. The material is validated by virological sampling studies, by the internal consistency of the figures, and by reference to what is happening in other geographical areas. The feasibility of the system has been demonstrated (even under epidemic conditions), and it is suggested that a national co ordinating system be established. PMID- 6926839 TI - The ecology of Diphyllobothrium latum. AB - The life cycle of the broad tapeworm Diphyllobothrium latum is discussed. To complete its development from egg to adult worm the parasite has to pass through two obligatory intermediate hosts before invading its final host. At each stage critical ecological parameters have to be encountered, among them oxygen concentration, light intensity and temperature. The first intermediate host, which remained unknown for a long time, is one of many copepod species; the second hosts are fish, notably species belonging to the genera Esox. Perca and Lota. The parasite remains in the latter until eaten by Man and his domesticates. The prerequisites for the parasite's development are precise, and the elimination of only one is sufficient to free an area of infection. PMID- 6926842 TI - The clinician's role in environmental protection. AB - The clinically working medical doctors are insufficiently trained in epidemiology and community medicine. They are, therefore, not sufficiently aware of health related environmental factors. They cannot avoid the difficulties of generalizing clinical observations because of small numbers and the long latency period in chronic disease evolution. As centralization of treatment is not generally possible we must improve our systems for registration of environmentally induced disease and health monitoring of the population. Finally, the clinicians should be more concerned with follow-up of administrative disease preventing actions. PMID- 6926845 TI - Social factors and leprosy in Lamjung, West Central Nepal: implication for disease control. AB - Such is the ability of leprosy to generate misconceptions and fears, that many patients are reluctant to be identified. Deformity and paralysis which may occur compound the stigma attached to this rare disease of slow insidious onset. Epidemiological studies of leprosy refer only to known disease and often to highly selected groups of the population. Cohorts are therefore incomplete, and variations in prevalence may reflect social attitudes and data reliability. This paper describes the demographic and spatial distribution of leprosy in Lamjung, a district of west central Nepal. Variations in known leprosy prevalence between sexes, ethnic groups and areas are related to social and physical factors. An apparent paradox of low leprosy prevalence in an ethnic group with a high proportion of infectious leprosy is associated with adverse social attitudes and poor survey coverage. Although the data are too limited for an epidemological analysis variations associated with social and physical factors have crucial implications for disease control. PMID- 6926844 TI - Some health problems of the Maldives. AB - It is difficult to quantify the major health scourges from which the Maldivians suffer because of the scattered nature of their settlements and their conservative attitudes to health and hygiene-related matters. Projects to improve the quality of the health and disease data have been instituted by the World Health Organization (WHO) and the Maldivian Ministry of Health. The paper analyses information that has since become available on three major ill-health conditions in the Maldives, namely infant deaths, malaria and leprosy. PMID- 6926846 TI - Specifying morphological factors affecting rates of death due to malignant neoplasms. AB - This paper reports research which examines the relations between select social morphological factors of population size and density and rates of death due to malignant neoplasms among males and females within countries in the north-east and west regions of the U.S.A. between 1960 and 1970. Generally it was found that populations having a stable morphological structure have a negative relation with rates of death due to malignant neoplasms; populations experiencing a change in population morphology, particularly an increase in the number of persons per housing unit, have a positive relation with rates of death due to malignant neoplasms. The importance of tapping different dimensions of the spatial environment is illustrated as future research on the social epidemiology of malignant neoplasms is suggested. PMID- 6926843 TI - Studies of lead and cadmium exposure in Glasgow, U.K. AB - Domestic water and whole blood samples were collected early in 1981 from two hundred volunteers living in the Glasgow area of Scotland, U.K. The concentration of lead in the water and blood samples, and of cadmium in the blood, was measured. The blood lead and cadmium concentrations were compared to those obtained in the Survey of 1979. There has been a fall in blood lead concentrations since the 1979 Survey. In contrast, the blood cadmium levels had remained similar. This diminution in blood lead concentration is attributed to a fall in water lead concentration caused by raising the pH of the water supply in the Glasgow area. The main determinant for cadmium in blood appears to be cigarette smoking habits, which had not changed. PMID- 6926847 TI - Medical, veterinary and environmental liaison activities in Scotland. AB - The past decade has seen many changes in the relationships between the medical, veterinary and environmental health professions in Britain. Doctors and veterinarians had traditionally tended to remain in isolation to each other despite mutual interests, while working relationships between public health doctors and environmental health officers were disrupted following re organization of the NHS in 1974 and of local government in 1975. The situation was, however, generally less acute in Scotland where active encouragement had been given since the early 1970s towards the creation of local liaison groups in different areas of the country, the first of which was formally established in Aberdeen in 1969. The subsequent development of other liaison groups and the role of the Communicable Diseases (Scotland) Unit in coordinating inter- and intra professional liaison and communications throughout Scotland is described, along with examples of combined activities in surveillance, investigation and control measures. PMID- 6926848 TI - Granulocyte functions in patients with insulin dependent diabetes mellitus. PMID- 6926849 TI - Teenage rebellion--current state of delinquent behaviour among Japanese adolescents. PMID- 6926850 TI - Detection of monoclonal antibody-defined colorectal carcinoma antigen by solid phase binding inhibition radioimmunoassay. AB - We have established a solid-phase binding inhibition radioimmunoassay for the detection of colorectal carcinoma-specific antigens in tissue culture supernatants of human colorectal carcinoma cell lines and in serum and urine of colorectal carcinoma patients. Using the [3H]glucosamine-labeled cell membrane glycolipid antigen and colorectal carcinoma-specific monoclonal antibodies in this assay, we have been able to detect several human colorectal carcinoma membrane-specific antigens that are released from the cell membrane into tissue culture supernatants, and an antigen detected by antibodies 1116-NS-19-9 and 1116 NS-52a that is found only in the serum and urine of cancer patients. PMID- 6926851 TI - Monoclonal anti-erythrocyte auto-antibodies from unimmunized NZB mice. AB - In order to study the heterogeneity of the anti-erythrocyte auto-antibody response in NZB mice, we have developed hybridomas producing monoclonal auto antibodies with anti-erythrocyte activity. These monoclonals were prepared by fusion of NZB splenocytes with the P3 X 63.Ag8 myeloma and were screened for activity by indirect immunofluorescence using flow cytometry. We have produced a variety of monoclonal anti-red cell auto-antibodies that have differing antigenic reactivities and immunoglobulin isotypes. Eleven monoclonal antibodies extensively studied thus far react with intact mouse erythrocytes, whereas only two of the eleven also cross react with sheep erythrocytes and bromelain treated mouse erythrocytes. These results suggest that the fusion pattern may represent the range of anti-red cell auto-antibodies found in the intact NZB mouse, with the exception of monoclonal auto-antibodies against cryptic red cell auto antigens, which were not demonstrated in this initial fusion study. PMID- 6926852 TI - Abstracts from the First Annual Congress for Hybridoma Research. February 15-17, 1982. PMID- 6926853 TI - Abstracts from the First Annual Congress for Hybridoma Research. February 15-17, 1982. PMID- 6926854 TI - Antigens of human melanoma as defined by monoclonal antibodies. Second workshop on monoclonal antibodies to melanoma. National Institutes of Health, National Cancer Institute, Bethesda, Maryland, USA, April 26-27, 1982. PMID- 6926856 TI - [Blocked centromedullary nailing in the treatment of diaphyseal fractures of the femur and tibia]. PMID- 6926855 TI - [Main indications for the use of external fixation devices in extensive traumatic lesions of the lower extremity]. PMID- 6926857 TI - [Surgical lengthening and contralateral shortening in Ollier's chondrodysplasia]. PMID- 6926860 TI - [Clinical contribution to the study of stenosis of the vertebral canal in achondroplasia]. PMID- 6926858 TI - [Our experience in the treatment of closed diaphyseal fractures of the leg with the AO technic]. PMID- 6926859 TI - [Development of the scoliotic curve: computer analysis]. PMID- 6926861 TI - [Mechanisms determining clinical and therapeutic aspects of the movement of a hip prosthesis due to a rupture of the shaft]. PMID- 6926862 TI - [Osteosynthesis of fractures of the femur neck]. PMID- 6926864 TI - [Supracotyloid osteonecrosis in the adult]. PMID- 6926863 TI - [Considerations on 3 cases of resurfacing hip prosthesis]. PMID- 6926865 TI - [Joint distraction of the hip (clinical experience)]. PMID- 6926867 TI - [Unusual uses of arthrography of the hip: chondro-osteo-dysplasia and the outcome of suppurative arthritis]. PMID- 6926866 TI - [Cystic degeneration (geode) of the acetabulum]. PMID- 6926868 TI - [Biomechanical changes in interventions for femoral-rotular arthrosis]. PMID- 6926869 TI - [Tibial osteotomy: review of our cases and study of variations of plantar support]. PMID- 6926870 TI - [Tibial osteotomy in the therapy of the arthritic genu varum]. PMID- 6926871 TI - [Patellectomy in femoral-rotular fractures and arthrosis]. PMID- 6926872 TI - [Primary extratorsion of the tibia]. PMID- 6926873 TI - [Role of the popliteal muscle in postero-external injuries of the knee in athletes]. PMID- 6926874 TI - [Synovial plica syndrome: clinical aspects, diagnosis, therapy]. PMID- 6926875 TI - [Baker's cysts in rheumatoid arthritis: arthrographic-clinical study]. PMID- 6926876 TI - [Surgical treatment of habitual luxations of the shoulder: our experience]. PMID- 6926877 TI - [Surgical treatment of acromio-clavicular dislocations by osteodesis and syndesmopexy]. PMID- 6926878 TI - [The painful shoulder in the vertebro-scapulo-humeral system]. PMID- 6926879 TI - [Dislocations and fracture-dislocations of the elbow (long-term follow-up study of 48 cases)]. PMID- 6926881 TI - [Fresh Monteggia's injuries in children]. PMID- 6926880 TI - [Fractures of the lateral condyle of the elbow in children]. PMID- 6926882 TI - [Clinico-therapeutic considerations and the importance of surgery in neurogenic para-osteoarthropathy]. PMID- 6926883 TI - [Indications for contact thermography in orthopedic-traumatologic pathology]. PMID- 6926884 TI - [Biologic treatment of osteoarticular tuberculosis: our experience]. PMID- 6926885 TI - [Diabetic osteoarthropathy. Clinical and pathogenetic considerations]. PMID- 6926886 TI - [Distal tibio-peroneal post-traumatic synostoses]. PMID- 6926888 TI - [Metastasis of endometrial carcinoma to the tarsus]. PMID- 6926887 TI - [The ligamentous component in dysplasia of the "coxa pedis"]. PMID- 6926889 TI - [Congenital hallux varus: surgical treatment]. PMID- 6926891 TI - [A note on an operative technic: adaptation osteosynthesis in a case of mixed epiphyseal detachment]. PMID- 6926890 TI - [Considerations on a rare case of detachment-fracture-dislocation of the nucleus of the femur head]. PMID- 6926892 TI - [Technical note on the postoperative treatment of Dupuytren's disease after sub total aponeurectomy using the Vigliani-Rodighiero method]. PMID- 6926893 TI - [A case of complex fracture of the lumbosacral spine]. PMID- 6926895 TI - [Nutritional osteomalacia. Description of a clinical case]. PMID- 6926896 TI - [A rare case of dysplasia epiphysealis osteochondromatosa (dysplasia epiphysealis hemimelica)]. PMID- 6926894 TI - [Bone cysts and their treatment with corticosteroids. Long-term results]. PMID- 6926900 TI - [A case of neurinoma of the posterior tibial nerve]. PMID- 6926897 TI - [A rare case of median nerve compression at the bend of the elbow]. PMID- 6926898 TI - [A rare case of hygroma of the back]. PMID- 6926899 TI - [A neurinoma localized first in the popliteal sciatic nerve and later in the median nerve]. PMID- 6926902 TI - [Bilateral osteochondritis of the nucleus of accessory ossification of the acromion]. PMID- 6926901 TI - [Scoliosis in Sotos' syndrome]. PMID- 6926904 TI - Disturbances of falling-staying asleep. PMID- 6926903 TI - [Rare case of bilateral non-ossification of the epiphyseal nucleus of the tuberculum of the first rib]. PMID- 6926905 TI - Use of Frenolon in the treatment of delusion of parasitosis "Ekbom's syndrome"). PMID- 6926906 TI - Changes in lipoproteins in response to Cavinton administration in aged hyperlipaemic patients. PMID- 6926907 TI - Microbiological and clinical examinations supporting the effectivity of oxolinic acid (Gramurin) in the treatment of acute enterocolitis. PMID- 6926908 TI - Involutional osteoporosis. PMID- 6926909 TI - Examination of the pain relieving-effect of intra-arterial No-Spa treatment of coxarthrosis. PMID- 6926910 TI - Considerations on the etiology of postponed labour. PMID- 6926911 TI - The effectivity of Bricanyl (terbutaline) treatment in the prevention and management of threatening abortion and premature delivery, respectively, within the frames of outpatients' services. PMID- 6926912 TI - Oro-facial dyskinesia treatment with the neuroleptic pimozide (Orap). PMID- 6926913 TI - Drug treatment of acute myocardial infarction. PMID- 6926920 TI - [Glucose-6-phosphate dehydrogenase in couples with habitual abortion]. PMID- 6926914 TI - Microbiological activity, pharmacokinetics and clinical use of tobramycin. PMID- 6926915 TI - Current problems of digitalis treatment. PMID- 6926916 TI - Bioavailability tests on various alpha-methyldopa preparations. PMID- 6926918 TI - Observations made with the simultaneous local application of metronidazole and miconazole in vulvovaginitis. PMID- 6926922 TI - [Transverse vaginal septum. Report of 3 cases]. PMID- 6926917 TI - Clinical observations with Naprosyn. PMID- 6926923 TI - View from the Nation's Capitol. PMID- 6926921 TI - [Value of monitoring the antepartum fetal heart rate]. PMID- 6926919 TI - [Therapeutic value of danazol in sterility associated with slight pelvic endometriosis]. PMID- 6926924 TI - View from the Nation's Capitol. PMID- 6926925 TI - View from the Nation's Courts. PMID- 6926927 TI - View from the Nation's Courts. PMID- 6926926 TI - View from the Nation's Capitol. PMID- 6926928 TI - [Two new species of the genus Nematodirus, parasites of steinboks and chamois: Nematodirus ibicis sp. n. and Nematodirus rupicaprae sp. n]. AB - Two new species of the genus Nematodirus are described. The nematodes were collected from the gastro-intestinal tract of steinboks (Capra ibex) and chamois (Rupicapra rupicapra) of Parco Nazionale del Gran Paradiso (Italian Western Alps). The names Nematodirus ibicis sp. n. and Nematodirus rupicaprae sp. n. are proposed. PMID- 6926929 TI - [Appearance of Anguillicola australiensis Johnston and Mawson, 1940 (Dracuncoloidea: Anguillicolidae) in Anguilla anguilla of Lake Bracciano]. AB - Anguillicola australiensis Johnston and Mawson, 1940 is redescribed and reported for the first time from Anguilla anguilla of Lake Bracciano (Rome-Italy). It is suggested that the appearance of Anguillicola australiensis in european eels might be in relation with intercontinental live eels transfers. PMID- 6926931 TI - [A case of Cysticercus racemosus in man]. AB - The authors refer a new case of Cysticercus racemosus in man. The description of scolex morphology is given and the name C. racemosus, generally accepted for these larval formae, is discussed. PMID- 6926930 TI - [Human infestations by Trichostrongylus axei, T. capricola and T. vitrinus: 1st report in Italy]. AB - The authors refer the first report in Italy of human infection with Trichostrongylus axei and Trichostrongylus vitrinus. Further studies are in progress on 68 male specimens identified as belonging to Trichostrongylus capricola group. PMID- 6926932 TI - Human subcutaneous dirofilariasis. 1. Two new cases in Venice. Identification of the causal agent as Dirofilaria repens Raillet and Henry, 1911. AB - Two human cases of subcutaneous dirofilariasis are described in a 41 year-old woman and in a 14 year-old boy living in Venice Lido. In the first case, the development of a nodule at the left forearm had been preceded by generalized symptoms such as pruriginous urticarioid patches in various regions of the body, transitory swellings and 8% eosinophilia. From the nodule, an adult female of Dirofilaria repens was recovered with embryos visible in the uterus. In the second case, the parasite was localized in the scrotum, where it had caused an extensive oedema with the formation of a nodule having the size of a nut. An immature female specimen of D. repens was found. In both cases, the serological tests (Indirect Haemoagglutination and Bentonite Flocculation) gave significant titres specific for filariasis (1:256 and 1:20 in the first case, 1:128 and 1:5 in the second, respectively). A parasitological survey of blood samples from 145 stray dogs captured in the territory of the Venice municipality revealed the presence of D. repens in 8.3% of cases, D. immitis in 4.8% and Dipetalonema reconditum in 0.7%. This is the first time that the aetiological agent of human subcutaneous dirofilariasis was identified as D. repens in Italy. PMID- 6926933 TI - Human subcutaneous dirofilariasis. 2. A report of 5 new cases of Dirofilaria repens in central and northern Italy and of a sixth case with uncertain parasitological diagnosis. AB - Six new human cases of subcutaneous filariasis (histological sections) in Lombardia, Emilia-Romagna and Toscana are described. Five of them are to attribute to Dirofilaria repens, whereas some doubts exist with regard to one case. The findings are compared with histological sections of male and female specimens of D. repens and D. immitis recovered from naturally infected dogs. PMID- 6926934 TI - [Campula rochebruni (Poirier, 1886) Bittner and Sprehn, 1928, (Trematoda, Campulidae), parasite of the bile ducts of Stenella coeruleoalba (Meyen, 1883) (Odontoceti, Delphinidae) of the Mediterranean Sea]. PMID- 6926938 TI - [Report of a new host, Dama dama, of Dictyocaulus (Micrurocaulus) eckerti Skrjabin, 1931]. AB - Dama dama is reported as a new host for Dictyocaulus (Micrurocaulus) eckerti Skrjabin, 1931. A short description and a differential diagnosis from Dictyocaulus (Micrurocaulus) viviparus (Bloch, 1782) Railliet and Henry, 1907 is given. PMID- 6926935 TI - [Preliminary study on the occurrence of sylvan trichinelliasis in 589 foxes in the Province of Rome]. AB - A survey on 589 foxes for the control of trichinelliasis in the Province of Rome was carried out in collaboration with the gamekeepers of the Province of Rome. The presence of Trichinella larvae in masseters muscles was studied using trichinoscope and digestion methods. Five foxes out 589 were found infected; four infected animals were killed in the Prenestini and Simbruini mountains, one infected animal was killed in the plain north west of Rome. PMID- 6926939 TI - [Crassostrea angulata (Lamarck, 1819), synonym of Crassostrea gigas (Thunberg, 1793): morphological and genetic studies]. PMID- 6926936 TI - [Presence of a new Trichostrongyloidea (Nematoda) Nochtia (Nochtia) atelerixi n. sp. in an Erinacoidea (Insectivora) in Togo]. AB - Nochtia (Nochtia) atelerixi n. sp. (Nematoda, Trichostrongyloidea) of Ethiopian Erinacoidea. - Nochtia (Nochtia) atelerixi n. sp. is found in the intestine of the hedgehog Atelerix albiventris in Togo. It is distinguished from the two other congeneric species parasite of asiatic Primates, N. (N.) nochti Travassos et Vogelsang, 1929 and N. (N.) tani Le Van Hoa, 1966, mainly by the highest number of cuticular crests and spicules with six tips. PMID- 6926940 TI - The karyotype of Phlebotomus perniciosus with some observations on cytogenetics of Phlebotominae in relation to the other Psychodidae. AB - The karyotype of Phlebotomus perniciosus has been described. This consists of five pairs of chromosomes and includes a pair of heterosomes of XY type. Some observations on the karyotypic structure of Phlebotominae based on the comparison between Phlebotomus and Lutzomyia and between Phlebotominae and Psychodinae have been made, taking into account the taxonomical and karyological situation of the two groups. PMID- 6926937 TI - [Gastrointestinal helminths of wild ruminants: observations on the chamois (Rupicapra rupicapra L.) in the Val Belviso reserve]. AB - The results obtained in a survey on the gastrointestinal helminths of 32 chamois of the Riserva of Valbelviso on the Alpi Orobie are reported. All the animals were infested: the species identified with more frequence were O. circumcinta, M. marshalli, N. filicollis. Of great significance was the diffusion of N. filicollis, compared with other species of this genus, typical of the wild ruminants; Oe. radiatum, never previously observed in chamois, was also found. These results show that the promiscuity of wild and domestic ruminants in the pasture could interfere with the natural focality of the respective gastrointestinal nematodes. PMID- 6926941 TI - Cytogenetic studies on the malaria vector mosquito Anopheles arabiensis Patton in the Awash Valley, Ethiopia. AB - Blood fed female mosquitoes were collected from human dwellings in the Awash Valley, Ethiopia. Those identified morphologically as A. gambiae s.l. were preserved in Carnoy's fixative for later ovarian polytene chromosomes examination. Only one member of the A. gambiae complex, A. arabiensis, was found by such examination. The polymorphic inversions identified were 2Rb and 3Ra. The frequencies of these inversions were variable in different localities and the former inversion was found to form an altitudinal cline. PMID- 6926943 TI - Anopheles arabiensis in the Cape Verde archipelago. PMID- 6926942 TI - Separation of Anopheles merus from freshwater Anopheles gambiae by salinity tolerance test and morphological characters. AB - The separation methods for Anopheles merus from freshwater A. gambiae s.l. involving the use of salinity tolerance test, sensilla coeloconica, palpal ratio and palpal bands were evaluated for a period of one year on a total of about 340 mosquitoes. The salinity tolerance test method was found to be quite simple and reliable but unsuitable in disease transmission studies due to an interval of 2-3 days between the collection and dissection periods and also due to the fact that only a fraction of the mosquito sample is generally identified by this method. Although significantly higher proportions of sensilla coeloconica and palpal ratio were observed in A. merus as compared to freshwater A. gambiae s.l. these characters were found quite unreliable due to their overlapping between two mosquito groups. Sensilla coeloconica and palpal ratio used separately could separate respective percentages of 11.4 and 11.8 A. merus from freshwater A. gambiae s.l., while in combination they separated up to 40.9%. Percentages 4 banded palp mosquitoes accounted for about 32% in A. merus and 19% in freshwater A. gambiae s.l. All these characters also displayed some seasonal variations in the two mosquito groups. PMID- 6926944 TI - [Hibernal parasitism by Ixodes ricinus (L., 1758) of Felis catus domesticus in an urbanized area]. AB - In the first months of 1977 some adults of Ixodes ricinus (L., 1758) have been found on Felis catus domesticus in a newly urbanized area near Rieti (Lazio, Central Italy) which had been previously used as a grazing-ground for sheep. This finding, quite exceptional according to the literature, is explained in the following way: 1) the cat had not been recorded until now as an habitual host of any Ixodid species, but many species of this superfamily can infest the cat in absence of their habitual hosts; 2) in a continental temperature climate, in peculiar microhabitats and in presence of hosts, I. ricinus can remain active for the whole year; 3) in changing the environment, man can influence the life-cycle of the parasite: the niche abandoned by the natural hosts can be occupied by other hosts which may be in many ways better suited to the tick and more dangerous for man. This phenomenon appears to be principally linked with the urbanization. PMID- 6926946 TI - [Rupture of the interventricular septum following myocardial infarction. The dilemma of surgical indications]. PMID- 6926947 TI - [Ultrastructure of autologous saphenous vein grafts preserved at ambient temperature and hypothermically. Histological and electron microscopic study of immediate and short-term changes]. PMID- 6926945 TI - [Surgical treatment of acute forms of coronary insufficiency]. PMID- 6926948 TI - [Immediate and late results of endomyocardial fibrosis surgery]. PMID- 6926949 TI - [Surgical treatment of the hypoplastic aortic anulus]. PMID- 6926950 TI - [Surgical treatment of congenital cardiopathies in the 1st year of life. Results in 358 patients]. PMID- 6926951 TI - [Pulmonary atresia with interventricular communication. Angiographic and surgical aspects in 7 patients]. PMID- 6926953 TI - [Technical details in reoperation for valvular lesions]. PMID- 6926952 TI - [Double outlet of the right ventricle and left ventricle. Surgical treatment in 33 patients]. PMID- 6926954 TI - [Valvuloplasty for mitral insufficiency: technics and results]. PMID- 6926955 TI - [Late follow-up of patients with dura mater valves]. PMID- 6926956 TI - [Long-term results of valve replacement in children]. PMID- 6926958 TI - [Conversion of unipolar R-inhibited demand pacemakers into bipolar ones in the preoperative period, retaining the same pulse generator, in cases of inhibition due to myopotentials]. PMID- 6926959 TI - [Vascular problems in destructive pancreatic surgery]. AB - Obstacles of vascular type may hinder or prevent pancreatic destruction for tumours of the pancreas or periampullary tumours. Out of 72 major pancreatic demolitions (cephalic duodenopancreatectomy or subtotal pancreatectomy from rt to lt) there were vascular difficulties on 26 occasions (36%), of which 15 were in existence prior to development of the neoplasia (anomalies of rise and course of peripancreatic vessels, stenosis/obliteration of the common hepatic artery in pancreatic head or periampullary tumours) and 11 due to tumoral growth (direct involvement of the mesenteric-portal tract, the hepatic artery and the superior mesenteric artery). The technical solutions used are discussed individually in the light of the physiopathological repercussions consequent on any temporary or permanent interruption of important hepatic and splanchnic vascularisation vessels (hepatic artery and various mesenteric a.), in relation to operating mortality and the prospects of long-term survival. In the most complex cases of direct vascular involvement by the neoplasia, the Author's trend was orientated to a position which, while accepting demolition decisions useful for the widening of the surgical radicality margins, nevertheless avoids extensive demolition solutions imposed by conditions of necessity or considerations of principle that probably do not bring significant advantages as regards long-term prognosis for these tumours. PMID- 6926960 TI - [Peripheral schwannomas: a case report]. AB - The Authors present 10 cases of peripheral schwannomas observed in the Ancona University Surgical Clinic in the five-year period 1976-1980. An examination is made of the frequency of the various symptoms in relation to the different localisations, the diagnostic techniques, among which particular importance is attributed to echo tomography, and the principles underlying surgical treatment. PMID- 6926957 TI - [The use of peripheral vasodilators in the immediate postoperative period following cardiac surgery: comparative study of the effects of dianhydrosorbitol dinitrate and sodium nitroprussate]. PMID- 6926961 TI - [Perforation of the small intestine caused by closed abdominal injury (review of 16 surgically treated cases)]. AB - The cases of 16 patients undergoing surgical treatment for blunt rupture of the small bowel have been reviewed. Male sex was the most affected one, and the traffic accidents were the main cause of this lesion. A high incidence of multiple injuries was noted. Clinical features were often effective in establishing the diagnosis; when performed, peritoneal lavage was always usefull, whereas X-ray did not. Mortality rate was low, in spite of the regular attendance of associated injuries, depending upon early diagnosis and surgical treatment. Only one death is reported, due to the extend of shock, for the associated injuries. PMID- 6926964 TI - [Functional retraining in osteosynthesis of the femur]. AB - Kinesis therapy is now an integral and essential stage in osteosynthetic surgery. According to the different anatomical zones, a series of functional exercises designed to restore joint movement in fractures of the femur are described. PMID- 6926962 TI - [Papillomatosis of the bile ducts: a clinical case]. AB - A case of diffuse papillomatosis of the bile duct, treated with external biliary drainage, is reported on account of its rarity. The extent and anatomopathological characteristics of the lesion make radical surgery impossible, so that the above-stated surgical solution appears to the Authors to be the most suitable one for resolving the biliary stasis and consequent cirrhosis. PMID- 6926965 TI - [Hallux valgus: results of the surgical management of hallux valgus]. AB - The Authors purpose to analyse on the basis of a critical examination of the operated hallux valgus with 2 different surgical technics the causes of failure and to give more exact indications about choosing the right surgical system. PMID- 6926966 TI - [Incidence of painful pronation in pediatric traumatology]. AB - After examining the traumatic mechanism responsible for the lesion and considering the possible pathogenetic interpretations, the Authors pass to a description of the clinical picture and the simple but effective reduction manoeuvre. The attached cases tend to emphasize the by no means negligible frequency of painful pronation among childhood traumatisms, a condition often misunderstood and a source of wrong diagnostic interpretations. PMID- 6926968 TI - [Bloodless treatment of patellar instability; author's experience]. AB - The Authors discuss the cases treated in the Fatebenefratelli Hospital in Erba in the period 1975-80 and propose strengthening of the quadriceps muscle as first treatment of knee cap instability. PMID- 6926967 TI - [Atypical course of rheumatoid coxarthritis. Clinical and radiographic description of a case]. AB - Authors present an unusual case of rheumatoid hip arthritis. Clinical findings, great bone destructions and particular femoral head dislocation are principal characteristics of this case classified as osteolytic rheumatoid hip arthritis. PMID- 6926970 TI - Freestanding abortion clinics: services, structure, fees. AB - In 1981, The Alan Guttmacher Institute (AGI), in collaboration with the National Abortion Federation (NAF), conducted a survey of 240 abortion clinics to update information about clinic structure and the relationship of structural characteristics to services, policies and fees. The clinics surveyed were a stratified random sample of all non-hospital abortion facilities that provided 400 or more abortions in the United States in 1980. Among the findings are the following: Thirty-one percent of the clinics reported that they are nonprofit or tax-exempt corporations. The nonprofit clinics are not significantly different from for-profit clinics in either the number of patients they serve or the region of the country in which they are located. Twenty percent of facilities, although regarded as clinics by the AGI for research purposes, define themselves as physicians' offices. These offices are more often located in the West and have smaller caseloads than other clinics. They are also disproportionately located in states with high abortion rates, which suggests that private physicians in these states are more willing than doctors in other states to provide relatively large numbers of abortions in their offices. Two-thirds of the clinics are licensed, most of them by states, but some by cities and counties. Licensed clinics have larger caseloads than nonlicensed facilities, but they are no different in terms of the other characteristics measured in the study, including services offered and fee structure. Fifty-four percent of clinics provide abortions after 12 weeks since the last menstrual period (LMP), and 24 percent, past 14 weeks.(ABSTRACT TRUNCATED AT 250 WORDS) PMID- 6926969 TI - The risk of premarital first pregnancy among metropolitan-area teenagers: 1976 and 1979. AB - Among sexually active teenage women living in metropolitan areas of the United States, the risk of premarital pregnancy within two years of first sexual intercourse rose from 32 percent in 1976 to 36 percent in 1979. As of 1979, 33 percent of unmarried white teenagers, and 43 percent of unmarried black teenagers, had conceived within 24 months of becoming sexually active. The increase in pregnancy risk between 1976 and 1979 was relatively greater for whites than for blacks at three, six and 12 months after first intercourse. The reverse was true at later intervals. The risk of pregnancy is disproportionately concentrated in the early months of sexual activity. Forty-five percent of all premarital pregnancies among those interviewed in 1979 had been conceived within the first six months of sexual activity, and 36 percent had been conceived within three months. In 1976, 27 percent of teenagers who had become sexually active before the age of 15 were premaritally pregnant within two years. By 1979, this proportion had risen to 41 percent--a 52 percent increase in the risk that accounts for almost all of the total three-year increase in premarital pregnancies among sexually active teenagers. The most pronounced increase in risk of pregnancy was registered among whites who became sexually active when they were younger than 15. Their 24-month probability of conception rose from 20 percent in 1976 to 39 percent by 1979. Levels of risk for unwed teenagers who initiated intercourse at ages 15-19 increased relatively little.(ABSTRACT TRUNCATED AT 250 WORDS) PMID- 6926971 TI - Administrative, counseling and medical practices in National Abortion Federation facilities. AB - A survey of members of the National Abortion Federation (NAF), most of them non hospital facilities, responsible for performing almost half of the abortions in the United States, was carried out by the NAF in 1981. Among the principal findings were the following: Fifty-three percent of the NAF facilities are freestanding clinics operated for profit. Fifty-one percent are open more than 50 hours per week, and 77 percent are open six days a week; 86 percent are open on Saturdays. Seventy-five percent of the physicians performing abortions in these facilities are gynecologists. Counseling provided by specially trained abortion counselors is a unique contribution of abortion facilities to health-care delivery. Virtually all facilities employ counselors who are neither doctors nor nurses. Most NAF facilities have more counselors than nurses and more nurses than doctors. Counseling in virtually all facilities includes providing written as well as verbal information about the nature of the procedure and its medical risks; such information is given to the patient so that she can give informed consent for the abortion. Almost all facilities include information about contraception and about the options available to a woman with a problem pregnancy. Most offer counseling to the male, as well as the female partner, on the patient's request. Twenty-eight percent of facilities generally provide both individual and group counseling. Where only one type of counseling is provided, it is usually individual counseling.(ABSTRACT TRUNCATED AT 250 WORDS) PMID- 6926972 TI - Reproductive mortality. PMID- 6926975 TI - Infertility and age: an unresolved issue. PMID- 6926974 TI - Differential fertility in the United States: 1976-1980. PMID- 6926973 TI - Low fertility in Europe: a report from the 1981 IUSSP meeting. PMID- 6926976 TI - Infertility and age: not so unresolved: a reply. PMID- 6926978 TI - The challenge of rheumatic fever and rheumatic heart disease in India. PMID- 6926977 TI - Recent advances in the management of hypertension. PMID- 6926984 TI - M-mode and two-dimensional echocardiographic features of atrial myxomas. PMID- 6926979 TI - Epidemiology of rheumatic heart disease--a study of 29,922 school children. PMID- 6926980 TI - Programmable pacemakers. PMID- 6926982 TI - Tetralogy of Fallot: clinical and haemodynamic profile. PMID- 6926981 TI - Infective endocarditis: East and West. PMID- 6926983 TI - Cardiac valvular prosthesis: an indigenous approach to development. PMID- 6926986 TI - Teletransmission of electrocardiographic waveforms: an indigenous and low priced technique. PMID- 6926985 TI - Effect of verapamil on retrograde VA conduction and its comparison with antegrade AV conduction. PMID- 6926987 TI - Endomyocardial fibrosis in Kerala State. PMID- 6926988 TI - Viruses, genes, and cancer. PMID- 6926990 TI - Biogenesis of the outer membrane of Salmonella. PMID- 6926992 TI - On some clinical implications of action language. AB - Schafer's action language can be criticized on purely theoretical grounds; here, the emphasis is on some of its clinical implications. First, action language tends to put the patient into an adversary position with respect to the analyst; this interferes with the therapeutic alliance, discourages regression, and encourages self-consciousness and problem-solving reasoning. Second, action language tempts the analyst to use premature labels in place of ambiguous metaphors; premature clarification may undercut the process of analytic discovery. Third, a focus on action and responsibility, because it highlights conscious mechanisms and the secondary process, may run the danger of working against the analytic process. It may yield rationalization rather than insight and convey the message that the analyst does not take seriously the concept of the unconscious. Fourth, by emphasizing clarity in favor of metaphor, action language may put an unnecessary emphasis on rationality and may discourage the kind of groping self-exploration that is the essence of productive analysis. PMID- 6926989 TI - Control of intercellular communication by way of gap junctions. PMID- 6926993 TI - Gender and gender role. Panel report. PMID- 6926991 TI - The choice of a name: "Dora" and Freud's relationship with Breuer. AB - I have suggested that Freud's choice of the pseudonym Dora for his eighteen-year old hysterical patient, Ida Bauer, was over-determined. Dora, it seems likely, was named not only after Freud's sister's nursemaid, as Freud himself explained, but also after Dora Breuer, Josef Breuer's youngest daughter. This theory is based on an examination of the similarities in the lives and symptoms of Anna O. (Breuer's famous hysterical patient of 1880-1882) and Dora; on an analysis of the transferences and countertransferences in the cases of these two young women; and on evidences of the persistent significance of Josef Breuer in Freud's life after 1895. These specific inquiries also call attention to the nature of hysteria at the end of the nineteenth century and to the ever-present complexities of the physician-patient relationship. PMID- 6926994 TI - New directions in affect theory. Panel report. PMID- 6926995 TI - Construction and reconstruction: clinical aspects. Panel report. PMID- 6926996 TI - The development of masculinity: a cross-cultural contribution. AB - We have examined, using data from a Stone-Age New Guinea culture, two hypotheses regarding the development of masculinity: that a prolonged and too gratifying mother-son symbiosis threatens a boy's chances of becoming masculine and that a boy, to create masculinity, must raise a psychic barrier against the urge to be merged with his mother. The data show the hypothesized forces to be at work in these New Guineans much as in Western society. PMID- 6926999 TI - Platonic love, transference love, and love in real life. AB - Plato and Freud transformed our way of looking at love. In Plato's Dialogues one can trace the transition and transformation of the mythical view on love into philosophical conceptualizations. The waning of the mythical point of view created the demand for man to know himself, and love became a puzzle. Plato was the first to propose that erotic impulses can undergo sublimation to higher and desexualized aims. Freud was not a Platonist, but if we trace the history of certain ideas it becomes evident that Plato's influence on Freud went further and deeper than was assumed by previous psychoanalytic writers. Freud's conceptualization of the libido can be seen as a Latinized version of Plato's Eros. Some of the difficulties associated with the psychoanalytic use of the term sublimation go back to the Platonic origin of the term. Freud's conviction that tender and aim-inhibited love was a later transformation of sexual impulses also went back to Plato, as did his belief that aim-inhibited love endures longer than sexual love. Because erotic love impulses can be sublimated, transference love can be harnessed in the service of cure based on insight. Erotized transference is not based on the refinding of an early love object and therefore is less capable of yielding the therapeutic climate required for psychoanalytic treatment. Freud's treatment procedure confirms Plato's belief in the plasticity of Eros. PMID- 6926998 TI - A developmental line of gender identity, gender role, and choice of love object. AB - A schematic overview of the development of male and female gender identity has been presented with an attempt to formulate a developmental line. The steps include: (Table: see text) In discussion of these steps an effort was made to distinguish between core morphological or core gender identity--that is, the primary sense of being male or female, to which other aspects of gender identity are added over the course of development to eventually include a "mix" of masculinity and femininity; gender role identity, which includes the conscious and unconscious mental representations of dialogues with other people vis-a-vis one's gender identity as well as identification with role models; and the separate process of choosing a sexual partner orientation. These separate strands join together and intermingle to make up what we view globally as "gender identity." PMID- 6926997 TI - The role of analytic neutrality in the use of the child analyst as a new object. AB - The analyses of two children and one adolescent were presented to illustrate the concept that the neutrality of the analyst can be used not only to (a) establish a working, analyzing, and observing alliance, (b) permit the development, recognition, and working through of the transference neurosis, but also to (c) develop a sense of autonomy and self-esteem which had been contaminated by the neediness and lack of true empathy of the primary objects during the practicing and rapprochement phases of separation-individuation. For the patients discussed above, many ego functions which should have had a degree of secondary autonomy were either inhibited, enmeshed in conflict, or experienced as nongenuine, part of a "false self." It was as if the experience with the neutral analyst permitted an "autonomous practicing" that had not been possible during the period of separation-individuation. PMID- 6927001 TI - Serious illness in the analyst: transference, countertransference, and reality responses. AB - Serious illness in the analyst has a disruptive effect on the therapeutic process. Transference and countertransference responses are highly idiosyncratic and variable, but must be dealt with effectively when the therapeutic process is resumed. Some effects are relatively brief and immediate; others become manifest only after a significant delay. This paper uses the experience of such an illness to call attention to this topic which has been relatively ignored in the psychoanalytic literature. PMID- 6927000 TI - Man's reach. PMID- 6927002 TI - Serious illness in the analyst: countertransference considerations. PMID- 6927004 TI - Fixing women: devaluation, idealization, and the female fetish. AB - A particular ideal of femininity which has long been popular in our culture is the image of the esthetically perfect but behaviorally compliant woman. By comparing two clinical cases, I have attempted to show that this stylized image is sometimes part of a specific defensive structure, enacted in extreme forms as part of a perverse ritual. The idealized image is a secondary formation with roots in early transitional representations. As an adult defense, it isolates devalued attributes, particularly anal attributes, from an esthetic ideal and enables the narcissistically disturbed individual to effect an illusion of separation while maintaining compulsive control over a needed object. The enactment of this defensive pattern frequently requires the cooperation of a partner. Women comply not only for masochistic reasons or because of intimidation, but because the fetishistic ritual itself is often an important part of their defensive armory. Women who rely on the idealization provided by a partner as the major source of their self-esteem are sometimes willing to accept pathological features of a partnership rather than give up this narcissistic support. At the more creative end of the continuum between pathological and adaptive transitional representations, the idealized image of woman may lend a playful romantic tone to relationships between men and women. In its most compulsive manifestations, however, it tends to perpetuate superficiality and impedes understanding between the sexes. Patients in whom the ideal is elaborated in its most distorted forms offer a useful opportunity to explore the roots of these phenomena. PMID- 6927005 TI - Archaic introjects and the cosmology of H.G. Wells. AB - The roles of the archaic loving and hating introjects are traced in the early scientific romances and the life work of H.G. Wells. The preambivalent polarization of the early loving introjects of an archaic ego ideal (giving rise to utopian fantasies and, later, to promulgations of a new world state) and the early hostile introjects of an archaic superego (giving rise to fears of death and, later, to fears of cosmic dissolution) is represented in eschatological preoccupations with death, the Last Judgment, heaven and hell. These religious preoccupations are derivatives of wishes for maternal union and bliss on the one hand, and of castration anxiety and fears of personal annihilation on the other. Further transformations of the archaic introjects are traced through an indentification with the role of redeemer, and later, through his scientific studies, to an espousal of T.H. Huxley's teachings of organic evolution and to the development of cosmological themes in his work. PMID- 6927003 TI - The resolution of a transsexual wish in a five-year-old boy. AB - The brief truncated psychoanalytic treatment of a transsexual boy described in this paper demonstrates the development of transference reactions and their subsequent resolution. The analytic situation allowed this young patient to live out again his relationship with his parents in his relationship with the analyst, to recover from wishing to be a member of the female sex, and to work through his conflicted symbiosis with his mother. Carlos became able to individuate and disidentify from her into a separate male child, in order to be able to identify with, and accept, his own biological and psychological maleness. It is to be hoped that our success with this patient will encourage others to treat and study children suffering from gender identity problems via the psychoanalytic approach. PMID- 6927006 TI - Metaphors and isomorphisms: analogical reasoning in Beyond the Pleasure Principle. AB - The mind uses analogies in order to understand the unknown. The utilization of these is explored in Freud's writings and in science in general. Analogies can be metaphorical (figurative) or isomorphic (literal); the latter are used in the induction of scientific hypotheses. The distinction between these two forms of comparing can be ambiguous. The inappropriate transformation of metaphors into isomorphisms in the construction of theory leads to illegitimate inferences. This paper comments on the use of this type of vitiated logic in Beyond the Pleasure Principle, particularly with reference to Freud's comparison of protozoan biology with human psychology. PMID- 6927007 TI - The nature of the Oedipus complex in the Dora case. AB - In this paper we sought to study, through a detailed review of Dora's analytic material, the specific nature of her oedipal conflict and its expression in her treatment with Freud as manifested in her dreams, associations, and transference. We found that while Freud was surely correct in considering Dora's positive oedipal conflict as an important source of her psychopathology, the implication of her early regression to a phallic-oedipal position was not fully appreciated or interpreted, leading to her eventual premature termination. While Freud analyzed, largely following the end of the treatment, Dora's erotic love for Frau K., he did not see this love as deriving from an integrated phallic-oedipal complex which included competitive and castrative strivings toward men as well as wishes to love a woman from a phallic position. Thus we sought to extend Freud's analysis of the case by delineating the specific form of Dora's homosexual love, the genetic sources for it, and the aggressive wish toward men as they derive from a particular substage of the oedipal phase for females, the phallic-oedipal phase. We conclude that Dora's hostility toward Freud, her father and Herr. K. resulted not only from injured pride but, more basically, from her jealousy and rivalry with father for mother's love. In her treatment Dora's phallic-oedipal wishes became increasingly dominant. They were manifested in the transference with her first acting to engage Freud's interest and then thwarting his interpretive efforts, ultimately by leaving the treatment altogether. The case well illustrates the importance of understanding the role of the phallic-oedipal phase in female hysterical patients. PMID- 6927008 TI - The exit line: heightened transference-countertransference manifestations at the end of the hour. AB - Final comments in many contexts have privileged positions among the many communications we make to one another as human beings. Deathbed pronouncements are treasured for their alleged profundities. "Famous last words" are catalogued. As we listen to political debates, we are particularly attentive to the closing statements of the candidates in the belief that something of superordinate importance will be revealed in these final words. Patients who come to us for psychotherapy and psychoanalysis also convey special messages in their parting comments. Final words are heavily invested because they bear the feelings deriving from earlier separations, complete with the longings to fuse with the earliest objects. Moreover, the cathexis belonging to the object may indeed be displaced onto words. In this paper I have sought to delineate and to describe certain patterns of exit lines which may provide useful information for the clinician. These "last words" are saved for the hour's end to keep them out of the therapeutic process and to render the therapist impotent and unable to respond. However, the therapist need not despair because he can bring these comments into the following hour as the focus of much productive work. After all, as Scarlet O'Hara would say, "Tomorrow is another day." PMID- 6927009 TI - "Developmental lag" in the evolution of technique for psychoanalysis of neurotic conflict. AB - The practice of psychoanalysis of neurotic conflict has not--to the extent that might be expected--evolved a consistent use in technique of available knowledge of the ego's mechanisms of defense. This is primarily related to a general resistance that can usefully be regarded as a "developmental lag." The evidence for this, particularly in Freud's writings, is reviewed as are the observations of others who have made note of this phenomenon. Some of the reasons that have contributed to this resistance among analysts are discussed. PMID- 6927010 TI - Notes on critical examinations of the primal scene concept. PMID- 6927011 TI - The current psychoanalytic dialogue: its counterpart in Renaissance philosophy. AB - It is my premise that psychoanalysis is involved in a phase of metapsychological and technical debate typical during the course of intellectual history. In general, the more traditional school textually conceptualizes psychoanalysis as a natural, observational science involving subject-object duality, determinism, and causality, and tends to separate theory and practice, interspersing a force energy metapsychology. The recent critics of traditional theory view psychoanalysis as closer to cultural science and art. They do not subscribe to a strict determinism and conceptualize that they work more within a field of free will. Their tendency to keep theory close to practice leads to more experience colored, closer to the clinical, theoretical models. I have tried to provide some early evidence that, through mutual influence, a dialectic is rising above the heat of this debate, with each group incorporating some of the ideas of the other. At the same time, since all differences are not true polarities, and not all polarities can be reconciled, the possibility that psychoanalytic theory will necessarily reach a new level of synthesis must be looked upon with caution. It is hoped that a broad view of this theoretical struggle in psychoanalysis can be enriched by an awareness among its participants of the related counterparts in Western intellectual history. PMID- 6927013 TI - Psychoanalytic theories of the self. Panel report. PMID- 6927012 TI - Beyond lay analysis: pathways to a psychoanalytic career. Panel report. PMID- 6927014 TI - [Cytophotometric study of the DNA content of the liver of rats poisoned with N nitrosomorpholine]. AB - The evolution of ploidy of liver cells during malignant transformation by N nitrosomorpholine was studied cytophotometrically. It was observed an increased ploidy that was due to the toxic action of the product and lasted six weeks, and a gradual return to normal values after the administration of the drug was discontinued. PMID- 6927016 TI - [Antineoplastic drugs used as fluorochromes]. AB - Several synthetic imide derivatives of naphthalic acid that bind to DNA and have anti-neoplastic properties are studied here in relation to the fluorescence they produce in the chromatin of chicken nucleated red blood cells. PMID- 6927017 TI - [Computerized models of the variation of the different stages of the cell cycle in a hypertriploid Ehrlich ascites tumor in the early days after implantation]. AB - The duration of the cell cycle of Ehrlich ascites cancer cells changes with the age of the tumor. Mitotic index shows the minimal values between the third and the fourth days. The authors propose a computerized model to analyze the mitotic rhythm of cell populations. PMID- 6927015 TI - [Characterization of brain tumors in vitro]. AB - The characteristics of brain tumors in vitro are analyzed in relation to their morphology, ultrastructure, immunocytochemistry and cell growth, showing that it is possible to identify the cell origin and to know several biological characteristics of the primitive tumor. PMID- 6927018 TI - [Relation between teratocarcinoma cells and embryonic cells of the mouse. Potentialities and differentiation capacities]. AB - The authors isolated the embryoid bodies of intraperitoneal mouse teratocarcinoma growing as an ascitic tumor, according to their morphology. They compared them with the first stages of normal embryogenesis, and studied the differentiation possibilities of the different morphological types. PMID- 6927020 TI - [Detection of carcinogenic mycotoxins and the producer molds in dried fruits]. AB - The presence of carcinogenic mycotoxins in maize and peanut were studied by means of the Ames' test. Siloed corn showed the existence of strongly carcinogenic strains of fungi at a concentration higher than the minimum considered as save. Peanut samples contained concentrations of fungi that were considered as not dangerous. PMID- 6927019 TI - [Relation between the carcinogenic activity of conjugated polycyclic hydrocarbons and the form of their localized molecular orbitals]. AB - The carcinogenic activity of some compounds is linked to the electronic structure of their molecules. The authors calculate the localized molecular orbitals (LMO) by means of a topologic method they have developed, based in the electronic distribution of a single molecular region, that coincides or is next to the K region, instead of having to consider the two classical regions (K and L). PMID- 6927021 TI - [Effects of subacute treatment with clomiphene, ethamoxytriphetol (Mer-25), and nafoxidine on blood calcium and bone density in rats]. AB - The authors study the effect of clomiphene, ethamoxytriphetol and nafoxidine on calcemia and bone density of the rat. These antiestrogens induce hypercalcemia, reproducing the bone radiologic changes produced after castration. The different effects obtained in normal and ovariectomized rats are probably due to the small estrogenic activity of antiestrogens. PMID- 6927022 TI - [Changes in lipid metabolism which accompany thioacetamide-induced cirrhosis]. AB - Intraperitoneally-administered thioacetamide to rats produces the incorporation of 3H2O into the liver lipids during eight days, diminishing thereafter together with a decrease in 32P incorporation to phosphatidyl choline. Contrarily, the sphingomyelin incorporated 32P increases by the effect of the toxic action of the drug, while the 3H binding decreases. The cirrhosis-inducing agent possibly produces a shunt of the common CDP-choline precursor to the biosynthesis of sphingomyelin with detriment to the synthesis of phosphatidyl choline. The role of the unsaturation of fatty acids by thioacetamide is considered. PMID- 6927023 TI - [An experimental model for adjusting the rhythm of irradiation to the kinetics of the tissues to be irradiated]. AB - To obtain better results with radiotherapy it is necessary to take into account the tissue kinetics. Synchronized cell cultures in vitro show that the radiation induced mitotic delay and the survival curves are cell phase-dependent. It is necessary to follow the evolution of the different cell populations in the irradiated volume. It can be done using a distribution factor (fD), that may be defined as the quotient between the number of S-phase cells and the number of cells in the remaining phases at a given moment. PMID- 6927024 TI - [Endogenous factors in the pathogenesis of cancer]. AB - Some general considerations are made about the endogenous factors in cancer pathogenesis, writing about genetical susceptibility, hormonal factors, and the role of endogenous factors on the carcinogenesis mechanisms due to physical, chemical or biological agents. PMID- 6927025 TI - [The value of ajmaline in the delayed follow-up of patients with chronic Chagas' cardiopathy and bi- or tri-fascicular blocks]. PMID- 6927026 TI - [Systolic and diastolic arterial pressure gradients, in normotensive subjects, facing graded effort, according to age and sex groups]. PMID- 6927028 TI - [Diabetic polyneuropathy. Review apropos of 20 cases of the Diabetic Clinic of the Cordoba Hospital]. PMID- 6927029 TI - The Frederick Osborn Memorial Volume. Reprints. PMID- 6927027 TI - [Remote lymph nodes in the immunodiagnosis of cancer of the breast (prognostic value)]. PMID- 6927031 TI - [Endobronchial lipomas]. AB - The authors report three cases of endobronchial lipoma, and study the etiopathogenesis and the main clinical and therapeutical aspects of such neoplasiae. Both diagnosis and treatment should be timely, in order to prevent irreversible damages to lung parenchyma, compelling surgeons to mutilating operations making the function of the apparatus heavier. PMID- 6927030 TI - [Ledderhose disease (case considerations)]. AB - After a preliminary note, the Author gives the casuistic survey of 30 patients, surgically treated during 12 years about. Moreover, a per cent analysis is done about the different possibilities of incidence of Ledderhose's disease in the cases considered. As a conclusion, the Author remembers the operative technique which gave the best results. Wide partial aponeurectomy. PMID- 6927032 TI - [Our experience with selective proximal vagotomy]. AB - The authors show a casuistry of 125 operations of SPV, and comment on the clinical and physiopathologic presuppositions justifying the indications to SPV in the field of gastroduodenal peptic pathology. They report the results of the gastric probings, both basal and after stimulation with pentagastrin in the pre- and postoperative phase, and after a year. They face the problem of pyloroplastics, and appraise the elements indicating and contra-indicating it in association to SPV. PMID- 6927034 TI - [Blood amino acid pattern in thyreopathic patients. (pre- and post-operative analysis)]. AB - On the basis of the effects, demonstrated in vitro, of the thyroid hormones on the amino-acidic metabolism at cellular level, the Authors analysed the aminoacidogram of 15 thyreopathic patients. They remarked significant preoperative modifications of some amino-acids, coming back to standard values after operation. The authors think the preoperative modifications are to be ascribed to thyreopathy, whereas the postoperative ones depend on the surgical trauma. PMID- 6927033 TI - [Perforations in neoplasms of the colon]. AB - The authors show their experience about the surgical treatment of colonic perforations in course of neoplastic disease. Their casuistry is compared with those of other centres. PMID- 6927036 TI - [Popliteal aneurysm (therapeutic considerations)]. AB - The authors show a case of popliteal artery aneurysm they had the opportunity to observe. In consideration of the high percentage of surgical failures; recorded in the treatment of the complicate forms, they point out the importance of precocious diagnosis. The Authors think the termino-terminal arterial anastomosis after aneurysmectomy has very limited indications. PMID- 6927035 TI - [Surgical treatment of cancer of the splenic flexure]. AB - The authors report their experience in the surgical treatment of the cancer of splenic flexure. The neoplasiae arising in such place are usually diagnosed in a more advanced phase than in the other colon segments. This results in a survival at a shorter interval. PMID- 6927038 TI - [Peptic ulcer: proposal of a data collection chart for electronic processing]. AB - Given the high incidence of peptic-ulcer disease and the need to develop an adequate means of assessment of medical-surgical treatments, the Authors propose a clinical record card for computer processing. PMID- 6927037 TI - [Our experience with rare primary localizations of hydatidosis. Analysis of etiopathogenetic aspects]. AB - The authors relate their experience on seventeen cases of unusual localizations of Echinococcus cyst operated in the last fifteen years. They present a critical analysis of the different pathogenetic theories trying to explain the peripheral localization of the larva. It is made examination of the factors which would consent the passing through of the hepatic and pulmonary filter, the mechanisms that could avoid such filters and the hypothesis referring to the possibility of direct setting up. They dwell quickly on the peculiar pathogenetic aspects of the various observed localizations. PMID- 6927039 TI - [Generalized postoperative peritonitis: the meeting of surgery and resuscitation]. AB - Fifteen cases of generalized post-operative peritonitis (GPP) are reported. Twelve patients underwent surgical treatment with mortality rate of 25%; three patients did not undergo surgery with mortality rate of 66,6%. Diagnostic, prognostic and therapeutic aspects of this severe post-operative complication are considered to underline the importance of a precocius diagnosis and a timely reanimatory and surgical treatment for a favourable prognosis. PMID- 6927040 TI - [Truncal vagotomy and cholelithiasis]. AB - A group of 50 patients with total vagotomy plus pylorolasty are studied with pre and postoperative cholecystography in a four years follow-up. 50 patients with parietal cell vagotomy (selective vagotomy) served as control group. The AA. study the correlation of gallbladder dilatation with gallstones formation after total vagotomy. On the contrary parietal cell vagotomy prevents these dysfunctions. PMID- 6927042 TI - [Considerations on the surgical treatment of hallux valgus]. AB - The authors, after showing a critical analysis of the most interesting operations for correction of valgus big toe in the history of orthopaedics, show the technique they followed, as well as the results obtained, in a specimen chosen among the patients treated with such method. PMID- 6927041 TI - [Anesthesiologic considerations in geriatric surgery resulting from our experience]. AB - After considering the physiopathology of senescence, the Author, on the basis of his own experience, describes two anaesthesiologic modalities, congenial to the geriatric surgery: general anaesthesia by microdoses and peripherical anaesthesia, yet preferring the latter in the operative areas pertaining hereto. PMID- 6927045 TI - Gas-chromatographic determination of disopyramide with nitrogen detection. AB - A sensitive and specific method is presented for the quantification of disopyramide, a new antiarrhythmic agent, in blood plasma or serum. Aminopentamide, a chemically similar compound, is added to the biological fluid, and the two compounds are extracted with chloroform. The concentrated extract is treated with trifluoroacetic anhydride, resulting in the dehydration of the primary amide group of the drug and internal standard to the corresponding nitriles. The dehydrated derivatives are gas chromatographed and detected using a nitrogen-phosphorus detector. The method is applicable to the determination of the drug in plasma in the 1-10 microgram/mL concentration range. PMID- 6927044 TI - Simplified toxicologic monitoring of adriamycin, its major metabolites and nogalamycin by reverse-phase high pressure liquid chromatography, Part I: Analytical techniques for isolated human plasma. AB - A simplified method is presented for routine toxicologic analysis of the antineoplastic drug, adriamycin, and its major metabolites in human plasma. This method employs a single solvent extraction of plasma using an acetonitrile aqueous NaOH mixture, followed by reverse-phase isocratic high pressure liquid chromatographic (HPLC) analysis. Recoveries of greater than 95% are obtained for adriamycin and its two major derivatives over the range of concentration: 0.2 to 8.0 nmol/mL of plasma. This method of drug and metabolite isolation and HPLC analysis from human plasma provides an efficient and accurate approach to the individualized toxicologic monitoring of adriamycin pharmacokinetics and metabolism. PMID- 6927046 TI - Analysis of cocaine and cocaine metabolites by high pressure liquid chromatography. AB - A high pressure liquid chromatography procedure was developed for analysis of cocaine and two metabolites (norcocaine and benzoylecgonine) in biological fluid. Following extraction with chloroform/Isopropanol (3/2), chromatography is performed with a mu-Bondapak C-18 reverse phase column eluted with water/acetonitrile/methanol (8/1/1) containing 1% acetic acid and 0.3 M EDTA. Ultraviolet detection of individual compounds was made at 235 nm and quantitation was based on peak height ratio to internal standard. Detection limit based on 0.5 mL of sample is less than 1 microgram/mL. Confirmation of the individual compounds was made by direct probe mass spectral analysis of the eluted peaks and comparison to known standards. PMID- 6927043 TI - An integrated methodological approach to the computer-assisted gas chromatographic screening of basic drugs in biological fluids using nitrogen selective detection. AB - This paper presents the methodological aspects of a computerized system for the gas-chromatographic screening and primary identification of central nervous system stimulants and narcotic analgesics (including some of their respective metabolites) extracted from urine. The operating conditions of a selective nitrogen detector for optimized analytical functions are discussed, particularly the effect of carrier and fuel gas on the detector's sensitivity to nitrogen containing molecules and discriminating performance toward biological matrix interferences. Application of simple extraction techniques, combined with rapid derivatization procedures, computer data acquisition, and reduction of chromatographic data are presented. Results show that this system approach allows for the screening of several drugs and their metabolites in a short amount of time. The reliability and stability of the system have been tested by analyzing several thousand samples for doping control at major international sporting events and for monitoring drug intake in addicts participating in a rehabilitation program. Results indicate that these techniques can be used and adapted to many different analytical toxicology situations. PMID- 6927048 TI - A modified phenylfluorone method for determining organotin compounds in the ppb and sub-ppb range. AB - The phenylfluorone method for tin analysis has been modified to be specific for organotin samples in the ppb and sub-ppb range (4-.1 micrograms of tin). Two extractions of an aqueous solution containing bis (tri-n-butyltin) oxide (TBTO) and tin sulfate yield results which are quantitative for TBTO without interference from the tin sulfate. The extracts are wet oxidized with hydrogen peroxide and sulfuric acid. The tin is determined from its lambda max near 530 nm through its complex with 2,6,7-trihydroxy-9-phenylisoxanthane-3-one (phenylfluorone) in the presence of cetyltrimethylammonium bromide. A Beer Lambert plot is obtained in the range of 0.1 to 7.0 micrograms of tin/sample with slope of 0.0344 with a correlation coefficient of greater than 0.990. The method has been successfully used to analyze over 400 environmental samples. PMID- 6927047 TI - Encapsulated XAD-2 extraction technique for a rapid screening of drugs of abuse in urine. AB - This paper describes a novel technique for the rapid screening of drugs of abuse in urine involving extraction with encapsulated Amberlite XAD-2 resin followed by gas chromatographic analysis. Each capsule is fabricated as a rigid, porous, polypropylene sphere, 2 cm in diameter, and contains 300 mg of the XAD-2 resin. Two mL of urine is shaken with one capsule under slight positive pressure for eight minutes. A sequential extraction is employed to obtain separate elution of the acidic-neutral and basic drugs. Identification is by dual column gas chromatography. The results, as given for spiked urine samples containing 16 commonly encountered drugs, were found to be linear and reproducible over both the therapeutic and toxic ranges. Extraction efficiencies using the encapsulated XAD-2 technique are comparable to those reported in literature for XAD-2 column chromatography. The purity of the extracts, as seen from the gas chromatographic analysis, is demonstrably better than that seen with the conventional procedures. There was minimal interference from polymer bleed. The total volume of solvents used in the sequential scheme is 5 mL. Total extraction time to achieve dried residues is 15 minutes. PMID- 6927050 TI - Gas chromatography-chemical ionization mass spectrometry of cocaine and its metabolites in biological fluids. AB - A gas chromatographic-chemical ionization mass spectrometric (GC-CIMS) method is described for the determination of cocaine, benzoylecgonine, and norcocaine. The procedure uses stable isotopes as internal standards and a mixture of methane ammonia as chemical ionization reagent gas. Run-to-run and within-run coefficients of variation (%) are less than 10% and the method has a sensitivity of less than 5 ng/mL from 1 mL or 1 gram of sample. The procedure has been applied to a number of cases involving cocaine intoxication and analytical data from these are described. PMID- 6927051 TI - Acetaldehyde, methanol, and ethanol analysis by headspace gas chromatography. AB - This report describes a headspace procedure suitable for the gas chromatographic assay of acetaldehyde, methanol, ethanol and various other volatile substances in biological samples. Carbopack B coated with 5% Carbowax 20-M is compared to Carbopack C coated with 0.2% Carbowax 1500. Assay range, linearity and precision are reported for the Carbopack B material. PMID- 6927052 TI - [Proceedings of the 5th National Congress of Industrial Hygiene. Rome, 15-16 December, 1981]. PMID- 6927049 TI - Quantitative determination of 2-hydroxy-3-methoxy-6 beta-naltrexol (HMN), naltrexone, and 6 beta-naltrexol in human plasma, red blood cells, saliva, and urine by gas liquid chromatography. AB - Two gas liquid chromatographic methods differing mainly in sensitivity are described for the quantitative determination of 2-hydroxy-3-methoxy-6 beta naltrexol (HMN), a minor metabolite of naltrexone (NT), in human body-fluids. The methods also incorporate simultaneous determinations of naltrexone and its major human metabolite, 6 beta-naltrexol (beta-OL), in urine, serum (or plasma), red blood cells (RBC), and saliva. Flame ionization detection of the bis (trimethylsylil) trifluoroacetamide (BSTFA) derivatives provided sufficient sensitivity for quantitation of the bases in urine. However, lower levels in serum, RBC and saliva necessitated the use of more sensitive electron capture detection of the pentafluoropropionate (PFPA) derivatives of the bases. Because HMN and 6 beta-naltrexol PFPA derivatives have nearly identical gas chromatographic retention times, their separation was achieved by differential extraction, based on their different partition characteristics between aqueous and organic solvents. In the plasma of 4 subjects, 16 and 24 hrs. after 2 X 200 mg NT doses, the relative percentages were 23.1% HMN, 3.4% NT and 73.5% beta-OL. In urine samples collected at the same time as the blood samples the relative percentages were 14.4% HMN, 9.0% NT and 76.6% beta-OL. The nonpolar nature of HMN and the greater polarity of beta-OL may have influenced their differential distribution into RBCs and saliva. In the RBCs, 96.1% HMN and no significant amount of beta-OL was found, in saliva, 92.3% of beta-OL and no HMN was found. PMID- 6927053 TI - [Biological rhythms and their significance in drug therapy]. PMID- 6927055 TI - [Cholesterol content of the adrenal cortex of young and old female rats]. PMID- 6927056 TI - Accumulation of D-tagatose by D-galactose-grown mycobacteria. PMID- 6927054 TI - [Ascorbic acid content of the adrenal cortex of young and old female rats]. PMID- 6927057 TI - [Healing of circular wounds of the trachea. I. Collagen and water content]. PMID- 6927058 TI - [Healing of circular wounds of the trachea. II. Tensile strength]. PMID- 6927060 TI - [Healing of circular wounds of the trachea. IV. Histological study]. PMID- 6927061 TI - [Identification of chemical components of Melittis melissophyllum L]. PMID- 6927062 TI - [A new method of preservation of biologically active tRNA preparations]. PMID- 6927063 TI - [Synthesis of N-benzoxazolinone-2, N-benzothiazolinone-2 and N-benzimidazole arylideneacethydrazides]. PMID- 6927064 TI - [Comparison of the determination of glucose by the hexokinase method and its modification by glucokinase]. PMID- 6927059 TI - [Healing of circular wounds of the trachea. III. Changes in the tracheal lumen after end-to-end anastomosis]. PMID- 6927065 TI - [Glucose levels of the blood of rats after a single dose of chlorocholine chloride]. PMID- 6927066 TI - The kinetics of 32P incorporation into brain and liver ribosomal proteins from 14 day old chick embryos. PMID- 6927067 TI - [Glucose levels of the blood of rats after subchronic chlorocholine chloride poisoning]. PMID- 6927068 TI - [Effect of multi-component injections on selected indicators of the blood of experimental animals. I]. PMID- 6927069 TI - [Stability of aminophenazone anal suppositories prepared with selected hydrophobic bases]. PMID- 6927070 TI - [Effect of multi-component injections on selected indicators of the blood of experimental animals. II]. PMID- 6927072 TI - [Value of zonography in injuries of the skull]. PMID- 6927071 TI - [Effect of ointment bases on the absorption of hydrocortisone acetate from ointments]. PMID- 6927073 TI - [An investigation of benzine extract obtained from dill fruits (Anethum graveolens L.)]. PMID- 6927074 TI - [Various characteristics of the internal structure of the suprascapular nerve in man]. PMID- 6927075 TI - [Fascicles of the thoracodorsal nerve in human postnatal development]. PMID- 6927076 TI - [Diagnostic retropneumoperitoneum]. PMID- 6927077 TI - [The long thoracic nerve and its roots in human postnatal development]. PMID- 6927078 TI - [Urinary excretion of cortisol and cortisone in women in relation to age]. PMID- 6927079 TI - [Torsion of the greater omentum]. PMID- 6927080 TI - [Effect of agonists and antagonists of cholinergic M and N receptors on the GABA level and GAD activity of the rat cerebellum]. PMID- 6927081 TI - [Effect of agonists and antagonists of cholinergic N receptors on the GABA level and GAD activity of the rat hypothalamus]. PMID- 6927082 TI - [Diagnosis of non-neoplastic abdominal tumors in children]. PMID- 6927084 TI - [Radiography of the bladder]. PMID- 6927083 TI - [Effect of chlorfenvinphos on biochemical processes in the body]. PMID- 6927085 TI - [Stability of aminophenazone and phenobarbital in anal suppositories prepared with cocoa oil]. PMID- 6927086 TI - [Effect of impaired urine flow on enzyme activity in the ureteral epithelium]. PMID- 6927087 TI - [Comparative studies of non-specific esterase activity in the adrenal cortex of young and old rats]. PMID- 6927088 TI - [Alkaline phosphatase content of the adrenal cortex of young and old female rats]. PMID- 6927089 TI - [Evaluation of long-term results in 254 patients surgically treated by gastric resection for peptic ulcer]. AB - The authors checked 254 patients, operated on with gastric resection according to Billroth II for peptic ulcer, at an interval ranging from 7 up to 20 years from the operation, and, on the basis of the results recorded, these patients were subdivided according to Visick's grading (15,7% in grade 1; 30,6% in grade 2; 26,4% in grade 3 S; 4,7% in grade 3 I; 14,6% in grade 4). On the whole, the remote results were considered satisfactory in 205 patients (80,7%) and unsatisfactory in 49 (19,3%): the latter represent those included in Visick's grades 3 I and 4, wherein the most serious post-resection syndromes had been ascertained; their incidence appeared absolutely higher (91,8%) in the patients subjected to gastric resection for non-complicate peptic ulcer. The Authors therefore conclude the failures of such type of operation are to be ascribed, in high percentage, to uncorrect indications thereto. PMID- 6927092 TI - [Experience with vascular access in hemodialysis treatment of acute and chronic renal insufficiency]. AB - The authors develop a retrospective investigation about 97 arterio-venous fistulae performed on acute and chronic uraemic patients for hemodialytic purposes. The method followed by the authors is to surgically insert a cannula in the femoral vein in case of urgency, and to prevailingly perform arterio-venous fistulae in the chronic uraemic patients' wrist. In the cases of difficult vascular access, the authors perform an autologous graft of large saphena vein to upper limb, between sublacertic umeral artery and cephalic or basilic median vein, and describe its technique. PMID- 6927091 TI - [Vascular changes in postmastectomy "thick arm"]. AB - The authors, after shortly outlining some pathogenetic theories about postmastectomy "big arm", especially dwell upon the theory of the hindered venous discharge. They, subsequently, through a clear and interesting phlebographic iconography, illustrate ten of the 41 cases suffering from such syndrome, they recently had the opportunity to observe. On the basis of their own experience, and according to part of the literature thereabout, the authors think very probably the postmastectomy "big arm" is to be ascribed to the hindered venous reflux of upper limb (for thrombosis or compression), due to the operation of mastectomy. As a conclusion, they suggest the improvement or recovery of this syndrome by stepping over the stenosed venous tract through a by-pass. PMID- 6927090 TI - [Diagnostic value of pan-cavography in obstructed central venous return of intrinsic causes]. AB - The authors, after having analyzed the clinical patterns and the causes producing cava syndrome, propose a sequential diagnostic approach to it, whose course makes use of radiological procedures more or less invasive, and of endoscopic and histobioptic techniques. Among radiological investigations pan-cavography has allowed the authors to formulate the diagnosis of limited venous return because of intrinsic causes, conferring so an aetiological connotation and a physiopathological correlation indispensable for a correct and rapid therapy of the uncommon "intrinsic cava syndrome" of two patients, suffering respectively from "idiopathic thrombosis of superior vena cava, concerning also the beginning of inferior vena cava" and from "Fiedler cardiomyopathy". PMID- 6927093 TI - [Hyperhistaminemia in neoplasms of the breast]. AB - The authors analyse the course of the total haematic hystamine rate in 13 women with breast cancer. They find that neoplasm take a significant increase of the histamine rate in comparison with the controls, while the mastectomy quickly is followed by the normalization of these values. They conclude that, as already suggested for others kinds of neoplasms of the lung and gastroenteric tract, also in the neoplastic pathology of the breast, the haematic hystamine dosage is a useful parameter for the monitoring the course of the illness. PMID- 6927094 TI - [Zollinger-Ellison syndrome]. AB - After an exposition of the modern trends on the definition, ethiopathogenesis, symptomatology and therapy of the Zollinger-Ellison Syndrome, the authors presents a case of Z.-E. Syndrome, which occurred to their observation. PMID- 6927095 TI - [Clinical contribution to the topic of subphrenic abscess]. AB - The authors exam 8 subfrenic abscesses cases observed in the last 5 years in Fatebenefratelli Hospital of Milano - Emergency Surgical Department. After considering etiologic, clinical and therapeutic aspects of their casuistry, they remark the importance of the basal illness, particularly in secondary subfrenic abscesses which are the most part in their series and in the literature ones. In this series of cases they always used trans-abdominal laparatomy which never gave technical problems, so they underline it may be preferable in comparison with other surgical methods. PMID- 6927097 TI - [Nakajama's gastroduodenostomy. Case contribution]. AB - In general, after subtotal gastrectomy for gastroduodenal ulcus and antral carcinoma, the digestive tract usually is reconstructed by the Billroth II method. The author paint out the disadvantages of this method due to the exclusion of the duodenal transit; also emphasize the importance of the gastro duodenostomy according to Nakajama's modifications. PMID- 6927096 TI - [A rare pathologic association: an appendiceal mucocele in a strangulated properitoneal hernia]. AB - The authors refer about a case of mucocele contained in a strangled properitoneal inguinal hernia and they discuss its pathogenesis. PMID- 6927098 TI - [Intra-abdominal foreign bodies following laparotomy interventions: report of a case]. AB - The authors report their own observation of a case of post-laparotomic endoabdominal foreign body, which for a long period had remained asymptomatic. Starting from the clinical case, they effect a short study of such iatrogenic pathology, and state the diagnostic and therapeutic criteria thereabout. They subsequently dissertate on the possible preventing means. PMID- 6927099 TI - [Acute lithiasic cholecystitis, situs viscerum inversus, vena porta preduodenale (considerations on a clinical case)]. AB - Authors report a case of preduodenal portal vein in a woman 68 years old with acute cholecystitis in situs viscerum inversus adbominis and levocardia. Surgery was difficult. They shortly analyze also etiology and clinical manifestations of situs inversus and PPV, with related malformations. They conclude that it is important to recognize the presence of situs inversus preoperatively and everytime suspect other anatomical anomalies. PMID- 6927100 TI - [Treatment of varices of the lower extremities during pregnancy]. AB - The authors studied 500 pregnant women suffering from varicose pathology, they had the opportunity to observe in the years 1979, 1980, 1981. The range of age hit was between 18 and 46 years. A higher prevalence occurred in pluriparae (82.8%) in respect of primiparae (17.2%). As to the type of varicose pathology observed, 40% showed diffused teleangectasies; 30% essential varices weighing on small and large saphena; 20% associations of the two former types; 6.4% post phlebitic syndromes with insufficiency of the deep communicating vessels, and 3.6% pudendae venous ectasies. The medical treatment, aiming to avoid venous stasis and rise in weight, was effected in 94% of cases: in 40% of cases a choice was also done for a pharmacologic treatment with synthetic glucofuranoside compounds, interrupted in 3.5% of the patients for the arising of more or less various symptoms of gastric intolerance. In the remaining 6% of cases, it was essential to adopt the surgical treatment, always performed after the 4th month of pregnancy and in epidural anaesthesia. As to the surgical indications, the authors remarked the higher frequency for the post-phlebitic syndromes with incompetence of the deep communicating vessels and serious tropic alterations, affecting in the rate of 40% the operated patients and 2.4% the varicose pathology they aggregately had the opportunity to observe. The other indications were the surface thrombophlebites (33.4%), varices with remarkable subjective troubles and cutaneous alterations of average and serious importance (6,6%) and larger caliper varices in pluriparae (20%). The authors, in the several middle and long term follow-up, never recorded any relapses in the patients surgically treated. PMID- 6927103 TI - [Josamycin. Proceedings of the International Symposium on Josamycin. Milan, 5-6 March 1982]. PMID- 6927101 TI - [Incidence and clinical aspects of Meckel's diverticulum and its complications]. AB - Meckel's diverticulum is usually discovered at laparatomy and the AA. ful that it should be removed regardless of its pathology because of the difficulty in making a diagnosis and the significant mortality rate associated with its complications. PMID- 6927104 TI - Josamycin chemical determination in biological fluids. PMID- 6927102 TI - [Anatomo-pathologic and therapeutic considerations on the Papineau method]. AB - The authors study the treatment of bone infections through Papineau's technique, and emphasize the element they consider essential in the process restoring the loss of substance: the "bouton" according to the French School. On the basis of the experience deriving from the treatment of 22 patients, they subsequently point out the importance of local antibiotic therapy and, on the contrary, the inefficacy of the administration of antibiotics by general way, at least as far as the not strictly surgical period is concerned. PMID- 6927105 TI - [Correlation between plasma levels and dosage schedules in chemotherapy]. PMID- 6927106 TI - Erythromycin and other macrolide antibiotics. PMID- 6927107 TI - [Clinical use of macrolides]. PMID- 6927108 TI - [Josamycin in pneumonology: comparison of 2 different dosage schedules]. PMID- 6927109 TI - [Josamycin in respiratory pathology in children being treated with theophylline]. PMID- 6927110 TI - [Josamycin in streptococcal infections and pertussis]. PMID- 6927111 TI - [Experience in using josamycin in pediatrics]. PMID- 6927112 TI - [Controlled multicentric hospital experimentation in pediatrics: comparison between josamycin and erythromycin]. PMID- 6927113 TI - [Josamycin in the treatment of impetigo in childhood: comparison with erythromycin]. PMID- 6927114 TI - [Pharmacokinetics of josamycin in liver cirrhosis]. PMID- 6927115 TI - [Josamycin in urologic infections]. PMID- 6927116 TI - [Use of a new macrolide in elderly patients]. PMID- 6927118 TI - [Macrolides: place of josamycin]. PMID- 6927117 TI - [Clinical and pharmacologic studies conducted in Japan]. PMID- 6927119 TI - [Comparative activity of macrolide-glucoside antibiotics on recently isolated strains of aerobic and anaerobic bacteria "in vitro"]. PMID- 6927120 TI - [Activity of josamycin against anaerobic bacteria]. PMID- 6927121 TI - [Activity and antibiotic combinations of josamycin]. PMID- 6927123 TI - [Pharmacokinetics of josamycin in man and distribution in various compartments]. PMID- 6927122 TI - [Effect of josamycin on Toxoplasma gondii "in vitro"]. PMID- 6927124 TI - [Microbiologic determination of tonsil and ocular levels of josamycin in hospitalized patients]. PMID- 6927125 TI - [Diffusibility of 2 macrolide antibiotics into human extravascular fluids]. PMID- 6927126 TI - Gentamicin disposition in children with chronic renal failure. AB - Gentamicin (G) disposition in six children with stable chronic renal failure (CRF) and in nine children with normal renal function (NRF) was determined by pharmacokinetic analysis of serum G concentration versus time data obtained over an 8-hour period following the administration of an intravenous loading dose. ES TRIP curve fitting indicated that G disposition was best described by a biexponential function; however, a one-compartment open model also suitably characterized G disposition for an 8-hour period. Peak serum G concentrations were similar between the CRF and NRF groups, but concentrations were significantly different (P less than 0.005) at 8 hours following the loading dose. Also, significant differences (P less than 0.001) were found between the two groups for beta, t1/2 beta, plasma clearance, and k10. The relationship of creatinine clearance (Clcr) versus beta, described by the equation beta = 0.033 + 0.003 X Clcr (P less than 0.005, r = 0.97) permitted the best prediction of the G elimination constant from a parameter of renal function. This relationship remained linear over a broad range of Clcr values in our patients and in other previously reported children with CRF and NRF. PMID- 6927127 TI - Pharmacokinetics of cimetidine in critically ill children. AB - The pharmacokinetic behavior of cimetidine has not been described in children, and there is no authoritative guideline on cimetidine dosage for children. Cimetidine pharmacokinetics were studied after a single intravenous dose and during three, incremental rates of continuous infusion in critically ill children. The mean elimination half-life of cimetidine was 1.44 +/- 0.41 hours. Compared to adults, these children had a relatively faster clearance (14.21 +/- 2.85 ml/min/kg) of cimetidine and a larger apparent distribution volume (2.13 +/- 0.63 l/kg). Based on our results, it appears rational to initiate cimetidine at a daily dose of 24 mg/kg in critically ill children. PMID- 6927128 TI - The effects of diazoxide upon fetal and maternal hemodynamics and fetal brain function and metabolism. AB - The effects of maternal infusion of Diazoxide (D) were evaluated in two groups of experiments: Nine ewes and their five nonhypoxic fetuses; the remaining four fetuses were excluded because of the development of hypoxia prior to the study. D was directly administered intravenously (IV) to the six fetuses. In group 1 maternal and fetal observations were made at 0, 5, 15, 30, and 45 minutes. A 60 minute observation was also made for the maternal infusion studies. Maternal infusion of 5 mg/kg maternal weight significantly reduced maternal pH from the control value at 5 minutes. Maternal metabolic acidosis was indicated by concomitant significant reductions in base deficit (BD) and total bicarbonate (HCO3), both of which remained low for all subsequent time periods. Maternal lactic acid concentration also increased at 15 minutes, although not significantly. Maternal PO2 also fell significantly at 5 minutes, remaining significantly low for the remaining observations. A profound maternal hypotension was elicited at 5 minutes. All following observations for maternal blood pressure (MBP) were also significantly low. Fetal carotid arterial (FCA) pH declined significantly from the control period value at 15 minutes, remaining significantly low for the remaining observations. FCA O2% saturation (O2%) also witnessed a significant decline from baseline for all observations. FCA serum lactate level rose at 15 minutes; however, this was not deemed significant. No significant changes were seen in fetal brain metabolic rate of oxygen or glucose. Fetal electroencephalogram (EEG) revealed a definite hypoxic change in a majority of cases. In group 2, the effects of a direct fetal IV administration of 30 mg D (mean dose = 7.97 mg/kg fetal weight) were studied in six experiments. No significant changes in fetal acid base status or fetal blood pressure (FBP) were witnessed for the 45 minutes under scrutiny. Fetal heart rate (FHR) showed a short transient rise from baseline at 5 and 15 minutes, returning to normal thereafter. A slight significant decrease in O2% saturation and O2 content were seen only for the 5-minute observation. There were no significant changes of fetal brain function and metabolism observed following D administration to the fetus. The significant fetal hypoxia and acidosis witnessed through the maternal infusion but not in the direct fetal bolus administration were probably owing to profound maternal hypotension resulting in deterioration of uteroplacental perfusion and fetal "gas exchange." PMID- 6927130 TI - Lidocaine and mepivacaine in cord blood. AB - The concentrations of lidocaine and mepivacaine were measured in stored cord blood samples from 200 deliveries. Newborn and obstetrical charts were reviewed for 100 deliveries for study of the association between cord blood concentrations, drug and route of recorded administration, Apgar scores at birth, and symptoms of possible toxicity. Detectable concentrations were commonly found (117/200), but toxic (3 micrograms/ml) levels were uncommon (4/200). However, recovery studies indicate these levels underestimate maximal exposure because both lidocaine and mepivacaine levels were shown to decrease in refrigerated stored blood. Although toxicity was seldom suspected, diagnostic accuracy was poor. The diagnosis was missed in the two patients with very high levels (5.0 and 9.0 micrograms/ml) of mepivacaine and levels measured in two suspected cases of toxicity were both low (0.4 microgram/ml). Associations between Apgar scores, cord levels, and route of administration (especially for lidocaine) were examined for 65 full-term uncomplicated deliveries. However, evaluation of these associations is problematic because dosages given, time or route of administration, and/or Apgar scores were often either not given or inconsistent with the clinical history. Detectable and potentially clinically significant local anesthetic drug concentrations were found in cord blood after all methods of administration, including local infiltration. These levels appear to underestimate the level of exposure because of instability of these anesthetics in stored cord blood samples. Local anesthetic toxicity appears to be difficult to detect clinically and may require cord blood level monitoring to detect. PMID- 6927129 TI - Effect of magnesium sulfate on maternal and fetal hemodynamics and fetal brain function and metabolism. AB - The hemodynamic effects, brain function, and metabolism of magnesium sulfate (MgSO4) were studied in seven fetal sheep experiments at 139 +/- 1.3 SE days of gestation. MgSO4 was intravenously infused to six gross-bred pregnant ewes at a rate of 4 gm/4 minutes as a loading dose, and 1.5 gm/60 minutes as a maintenance dose. There were no significant changes in maternal pH, PO2, O2 saturation, O2 content, HCO-3, glucose or lactate concentrations, or blood pressure at the end of the infusion. However, maternal heart rate decreased significantly from the mean baseline of 117 +/- 12.4 beats/minute at the end of the 60-minute infusion but recovered 30 minutes later. Uterine blood flow remained unchanged. Maternal Mg2+ levels rose significantly (P less than 0.005) at 60 minutes and remained elevated. No significant changes in fetal pH, PO2, PCO2, lactate, and Mg2+ concentration were noted during infusion. However, fetal heart rate increased significantly (P less than 0.025) at the end of infusion. Fetal hypotension was also noted at the end of the infusion (P less than 0.02). Cerebral blood flow did not change significantly throughout the experiment. However O2 consumption decreased temporarily at 15 and 30 minutes into infusion, which returned to baseline thereafter. Fetal glucose consumption and electroencephalogram remained unchanged throughout the experiment. Maternal infusion of MgSO4 does not exert any deleterious effects on the acid-base status of the mother or fetus. It increases the fetal heart rate and causes fetal hypotension, without any significant effects on the fetal brain function and metabolism. PMID- 6927133 TI - [Drugs and pregnancy]. PMID- 6927131 TI - [Ejaculatory impotence as a cause of male infertility]. PMID- 6927132 TI - [Monitoring experimental quality in tubal microsurgery]. PMID- 6927135 TI - [Reproduction in adolescence]. PMID- 6927134 TI - [Colpoperineogram in pre- and postoperative periods of prolapse patients]. PMID- 6927136 TI - [Pelvic thrombophlebitis. Medical treatment. Report of 3 cases]. PMID- 6927139 TI - [Tubal litigation by minilaparotomy]. PMID- 6927137 TI - [Pregnant adolescents from the urban population sectors. Socio-demographic and family features]. PMID- 6927140 TI - [Twin pregnancy and malformation of one of the fetuses]. PMID- 6927138 TI - [The microsurgical training of the gynecologist]. PMID- 6927141 TI - [Evaluation of 5 years' work of the Centro de Proteccion de la Embarazada Rural of the Hospital de Traiguen ("Casa de la Embarazada Rural")]. PMID- 6927143 TI - [Urinary estriol in high-risk pregnancies. Bibliographic and clinical review]. PMID- 6927142 TI - [Colpoperineogram or video colpocystogram and the use of the colpoperineogram]. PMID- 6927144 TI - [Thermographic diagnostic correlation and histopathological study in non malignant pathology of the breast]. PMID- 6927148 TI - [Iron reserves in the pregnant woman and the newborn infant: effects of an iron supplement]. PMID- 6927147 TI - [Typhic intestinal perforation and pregnancy]. PMID- 6927145 TI - [Nonstress monitoring in high-risk pregnancy]. PMID- 6927146 TI - [Tumors of the ovary in adolescence. Study of 21 cases]. PMID- 6927149 TI - [Diagnostic study of 114 infertile couples]. PMID- 6927150 TI - [Effect of silymarin in intrahepatic cholestasis of pregnancy (preliminary communication)]. PMID- 6927151 TI - [Chlamydias in daily clinical medicine]. PMID- 6927153 TI - [Hydatid cyst of the ovary, apropos of a clinical case]. PMID- 6927152 TI - [Treatment of hirsutism in micropolycystic ovary syndrome with estrogens and sequential prostagen]. PMID- 6927154 TI - [Cancer of the ovary in patients with previous ovarian preservation]. PMID- 6927155 TI - [Diagnosis and treatment of the tubo-ovarian abscess]. PMID- 6927156 TI - [Vaginal cancer]. PMID- 6927158 TI - [Genital prolapse and urinary incontinence. Perineal rehabilitation]. PMID- 6927157 TI - [Effect of cervical conization and of chloramphenicol on cervicovaginal anaerobics]. PMID- 6927159 TI - [Biopsy of endometrium by aspiration]. PMID- 6927160 TI - [Microsurgical tubal anastomosis. Technic and results in 12 cases]. PMID- 6927161 TI - [Materno-neonatal management and complications in patients with cardiac valvular prosthesis and in anticoagulant treatment]. PMID- 6927162 TI - [Outcome in resuscitation patients]. PMID- 6927163 TI - [Postoperative intravenous morphine analgesia. Use of a computer-controlled automatic syringe]. PMID- 6927164 TI - [Alleviation by fentanyl of the cardiocirculatory effects related to intubation]. PMID- 6927165 TI - [Velopharyngoplasty in myasthenic patients. Anesthesia-resuscitation problems]. PMID- 6927166 TI - [Postoperative septicemias]. PMID- 6927167 TI - [Severe strongyloidiasis in French Guiana. Apropos of 4 cases]. PMID- 6927169 TI - [Management of postoperative oligo-anuria]. PMID- 6927168 TI - [Acute colonic pseudo-obstruction]. PMID- 6927170 TI - [Anesthesia in Paris hospitals]. PMID- 6927171 TI - [Clinical surveillance of wakening from anesthesia following 1006 regular operations]. PMID- 6927172 TI - [Diazepam and ketamine for voluntary interruptions of pregnancy]. PMID- 6927173 TI - [General anesthesia for cataract surgery in children]. PMID- 6927174 TI - [Peridural morphine analgesia in thoracic injuries]. PMID- 6927176 TI - [Peridural anesthesia in an obstetrical myasthenic patient. Apropos of a case]. PMID- 6927177 TI - [Status epilepticus following voluntary poisoning with viloxazine]. PMID- 6927175 TI - [Diagnosis of catheter-related venous thromboses by isotopic phlebography]. PMID- 6927179 TI - [Postoperative agitation]. PMID- 6927178 TI - [Poisoning by orphenadrine chlorhydrate]. PMID- 6927180 TI - [Alcohol and the liver]. PMID- 6927181 TI - [Cholestasis]. PMID- 6927182 TI - [Cholelithiasis]. PMID- 6927183 TI - CSF immunoglobulins G in multiple sclerosis. AB - Three different methods were compared to detect an intrathecal IgG synthesis in cerebrospinal fluid of patients with Multiple Sclerosis. A preliminary investigation was carried out on serum and cerebrospinal fluid proteins fractionated by means of analytical isotachophoresis. This technique shows many advantages but isoelectrofocusing is still the most available technique in diagnostic trials. PMID- 6927185 TI - Narcissistic personality disorder as a regression to a preoedipal phase of phallic narcissism. AB - The Narcissistic Personality Disorder in males is described in terms of the presenting picture and the psychodynamics involving unconscious phallic narcissistic transferences and wishes. A regression to preoedipal phallic narcissism is reconstructed as having occurred in childhood. The permanency of this regression prior to analysis gives an impression of great tenacity and pathology, as if the narcissism had been arrested in its development. However, oedipal dynamics and transference neuroses do emerge from repression after several years of analysis. A hypothesis is proposed in agreement with the findings of Edgcumbe and Burgner (1975) that a preoedipal phase of phallic narcissism is a regular and universal phase of childhood development. A further hypothesis is offered based on the implications of the findings of Narcissistic Personality Disorder, that a two-step sequence of narcissistic development, followed by object libidinal development, occurs in the oral, anal, and phallic erotogenic zones. This hypothesis suggests the idea of three different types of Narcissistic Personality Disorders: the oral, the anal, and the phallic varieties. PMID- 6927184 TI - [Treatment with levamisole in a case of deficiency of the neutrophil granulocyte function associated with an increase in plasma IgA and recurrent dermal abscess infections]. AB - The authors describe a case of recurrent dermal abscess infections resistant to usual antibiotic therapy and demonstrating a failing of the activity of the neutrophils and a remarkable increase of plasmatic IgA. The treatment with Levamisole regularized the laboratory data and, as a result, determined a consequent important improvement of the patient. PMID- 6927186 TI - Physician suicide. AB - The topic of physician suicide has been viewed from several perspectives. The recent studies which suggest that the problem may be less dramatic statistically, do not lessen the emotional trauma that all experience when their lives are touched by the grim event. Keeping in mind that much remains to be learned about suicides in general, and physician suicide specifically, a few suggestions have been offered. As one approach to primary prevention, medical school curriculum should include programs that promote more self-awareness in doctors of their emotional needs. If the physician cannot heal himself, perhaps he can learn to recognize the need for assistance. Intervention (secondary prevention) requires that doctors have the capacity to believe that anyone, regardless of status, can be suicidal. Professional roles should not prevent colleague and friend from identifying prodromal clues. Finally, "postvention" (tertiary prevention) offers the survivors, be they family, colleagues or patients, the opportunity to deal with the searing loss in a therapeutic way. PMID- 6927187 TI - Social class and perceived improvement in therapy: the effects of therapist discipline and therapy type. AB - The present study approached the question of differential perception of improvement across social classes by various disciplines and therapeutic orientations. Records of 4,257 psychiatric patients were examined for type of therapy, discipline of therapist, rated improvement, and social class. For variables "type of therapy" and "discipline of therapist," the interaction term of analysis of variance was significant, indicating that some therapists (i.e., with a given therapeutic orientation) show greater differential among the social classes with regard to perceived improvement than others. Psychiatrists were found more reluctant to rate patients as improved, and responded less differentially among the classes than social workers and psychologists. With regard to therapeutic orientation used, therapists using family therapy or medication rated a higher percentage of patients improved in Class IV than in Class III. The results suggest that therapists with differential training backgrounds (either discipline or therapeutic orientation) have different perceptions of change in psychiatric patients, which may be due to their differential training. PMID- 6927189 TI - Integrating mental health and general health care. PMID- 6927188 TI - The child's accusation of sexual abuse during a divorce and custody struggle. AB - A single case report is presented in which the children, after a marital separation of their parents, accused the father and paternal grandparents of sexually assaulting them during the time the parents and children were still living together. The case illustrates the dilemmas that their allegations created for the therapist who was responsible for the children's evaluation during the custody suit. The therapist's efforts to resolve these dilemmas are described, and the case is discussed in terms of the literature on folie a deux. PMID- 6927191 TI - Site location and requirements for the installation of a nuclear magnetic resonance scanning unit. AB - The installation of a nuclear magnetic resonance unit in any diagnostic facility involves certain location and environmental requirements. Based on our experience with the FONAR QED 80 system, we have delineated the major factors which must be considered when planning for such an installation. The major requirements are location and space. Suggested layouts for the suite and the control room are included. Certain environmental specifications will vary depending on the location of the facility and the type of unit installed. PMID- 6927190 TI - Nuclear magnetic resonance imaging techniques as developed modestly within a university medical center environment: what can the small system contribute at this point? AB - This paper describes a geometrically small NMR imaging system which has been developed and assembled within a university medical center environment. Consideration is given to the technical specifications and basic economics for the magnet system, NMR spectrometer, and computer configuration. Initial research objectives for the system are outlined which include (1) the signal-to-noise improvement potential of rotational gradient imaging, and (2) 19F tracer imaging considerations with a detailed discussion concerning the feasibility of in vivo NMR imaging of 19F-fluorodeoxyglucose (2-FDG and 3-FDG). Finally, potentially significant areas for research within the constraints of a small NMR imaging system are described. PMID- 6927192 TI - In vivo NMR imaging and T1 measurements of water protons in the human brain. AB - Nuclear magnetic resonance (NMR) proton density images of the human brain have been made by the FONAR method. Spin-lattice relaxation times, T1, of water hydrogen protons have been determined at random positions within frontal and temporal regions of the human brain. The primary purpose of this ongoing research is to accumulate a large data base of normal T1 values for water protons in normal human brain tissue. Our experience to date includes 31 measurements on 18 volunteer subjects, and the mean value +/- standard deviation is 215 +/- 42 msec. In addition, two metastatic lesions of the brain were studied and found to have T1 values longer than those for normal brain tissue. PMID- 6927193 TI - Basic concepts for nuclear magnetic resonance imaging. AB - The basic concepts necessary to understand the physical basis of NMR imaging are presented in this didactic article. It is intended as a starting point for the radiologist or medical physicist who is addressing the topic of NMR for the first time. The basic of the NMR phenomena is described with introduction of the concepts of magnetic moment, magnetic fields, magnetic resonance, net magnetic moment of a sample, NMR excitation and NMR emission. The equipment necessary to observe these NMR properties of matter is summarized as well as the procedures for basic pulsed NMR experiments. The physical concepts for spatial localization of NMR emissions are introduced with physical analogies to stringed musical instruments. Several alternative imaging modalities are compared with greatest emphasis on the inversion recovery technique which yields images weighted by tissue T values. The six subsystems of an NMR imaging device (primary magnet, computer, radio equipment, magnetic gradient, data storage and display subsystems) are described in an overview fashion. The paper is followed by a series of study questions to test the reader's comprehension of basic NMR imaging concepts. PMID- 6927194 TI - Alterations in NMR spectra due to water of hydration. PMID- 6927195 TI - NMR and water proton relaxation in tissues. PMID- 6927196 TI - Head and body imaging by hydrogen nuclear magnetic resonance. AB - A hydrogen (1H) nuclear magnetic resonance (NMR) imaging study of the normal head, thorax, and limbs is reported. The images are 10 to 15 mm thick transverse slices obtained in 2 to 4 min using a two-dimensional Fourier transform technique. Spatial resolution in the imaging plane is about 2 mm, enabling the optic nerve and many small blood vessels to be observed. Thorax scans show details of the cardiac chambers, aorta wall, and lungs without artefacts arising from physiological motion. PMID- 6927198 TI - Cerebral energy metabolism in rats studied by phosphorus nuclear magnetic resonance using surface coils. AB - Phosphorus nuclear magnetic resonance with surface coils was used to investigate the regional metabolism of the rat brain in vivo under conditions of normoxia, severe hypoxemia, partial necrosis, and partial ischemia. The results show an increase in sugar phosphate and/or inorganic phosphate with injury in accordance with in vivo assays. The technique provides a powerful means of monitoring the metabolism of stroke and its response to therapy in vivo. PMID- 6927199 TI - Nuclear magnetic resonance evaluation of a leiomyosarcoma. PMID- 6927200 TI - Significance of water proton spin-lattice relaxation times in normal and malignant tissues and their subcellular fractions--I. PMID- 6927197 TI - Evaluation of muscle degeneration in inherited muscular dystrophy by nuclear magnetic resonance techniques. AB - Nuclear magnetic resonance (NMR) techniques were applied to study the muscular dystrophy in chicks. The water proton spin-lattice relaxation times (T1) of fast, slow, and mixed muscles and plasma were measured. The T1 values of dystrophic pectoralis major and posterior latissimus dorsi (PLD) were significantly higher than those of the normal pectoralis and PLD muscles. The present results establish a direct relationship between the differences in T1 values and the severity of muscle degeneration. Consistent with this conclusion, it was also found that the T1 values of muscles unaffected in muscular dystrophy, namely, the gastrocnemius, and anterior latissimus dorsi (ALD), were not different between the normal and dystrophic chicks. Although the affected muscles of dystrophic chicks contained higher percent water and fat than those of normal chicks, the results show that the higher T1 values in dystrophic muscles were not solely due to variations in their water content. The increase in the T1 values is principally a result of altered interaction between cellular water and macromolecules in the diseased muscles. These data also point out the potential use of NMR imaging in evaluating muscle degeneration. PMID- 6927201 TI - Prospective tissue-mimicking materials for use in NMR imaging phantoms. AB - Water-based proteinaceous gels, which--with appropriate additives--are stable with time and possess a high melting point, have been used as base materials in ultrasonically tissue-mimicking materials. In the present work, versions of these gels having various concentrations of glycerol and graphite particles were studied regarding their NMR T1 and T2 dependencies at a proton Larmor frequency of 10.7 MHz. It has been found that T1 depends primarily on the concentration of glycerol and T2 depends primarily on the graphite particle concentration. Also, the ranges of T1 and T2 likely span those which exist for soft tissue parenchymae. Thus, these materials are good candidates for use as NMR tissue mimicking materials. T1 and T2 also vary with gelatin concentration. The latter fact, together with the strong dependence of T2 on graphite concentration, mean that effective contrast-resolution phantoms and anthropomorphic phantoms with stable T1 and T2 distributions can be produced. PMID- 6927202 TI - Low field topical nuclear magnetism apparatus in a hospital area. AB - We describe the technique and the measure of the relaxation time T2 for the free precession of protons in the earth field. In vitro and in vivo experiments on human physiological fluids, including blood coagulation, are reported. We put forward the evident interest of this technique to study the meconium in the amniotic liquid and small quantities of oscite observed in situ. PMID- 6927203 TI - Significance of water proton spin-lattice relaxation times in normal and malignant tissues and their subcellular fractions--II. PMID- 6927204 TI - Practical methods for biological NMR sample handling. AB - The ability of NMR parameters T1 and T2 to be used to distinguish one tissue from another and diseased from normal tissues has wide application in diagnostic medicine. Measurement of such values in vitro on excised tissues and fluids was the basis for fundamental discoveries which provided the impetus for the development of in vivo clinical whole body NMR imagers. Therefore, as in vivo imaging grows, the need for screening and testing of new ideas in vitro will grow. The success of data collection in vitro depends greatly on the care and understanding with which biological samples are processed. This paper summarizes proven methods for handling of soft and firm biopsy material, blood components, body fluids, and culture cells. The effects of temperature variation and storage parameters are discussed for animal and human samples. The paper is a practical guide to the hows and whys of biological sample handling for NMR. PMID- 6927205 TI - An assessment of the safety of rapidly changing magnetic fields in the rabbit: implications for NMR imaging. AB - The effects of rapidly changing magnetic fields on the cardiac and respiratory functions of anaesthetised rabbits have been investigated. No changes were observed using pulsed fields with peak rates of change of 60 T/sec. The implications of these experiments for the safety of NMR imaging are discussed. PMID- 6927206 TI - A flow velocity zeugmatographic interlace for NMR imaging in humans. AB - We describe a flow sensitizing zeugmatographic phase-modulation interlace for NMR imaging which is exactly analogous to Lauterbur's spatial-location-sensitizing magnetic field gradients. The method may be implemented by minor modification of any NMR-imaging scanner without interfering with its conventional operation, and enables up to 6-D imaging of the joint (spatial-flow) density of spins delta (r,v). In a special simplification, specific-flow-density, mean value of v(r), and flow-current-specific-flow-density, rho 0(r)v, derive directly from "real' and "imaginary" parts of the image reconstruction. PMID- 6927207 TI - Role of 3D imaging in small scale NMR tomography. AB - Some advantages of using 3D techniques in small scale NMR imaging are suggested. In particular the 3D methods are likely to be useful in slow dynamical processes occurring in vivo. Three-dimensional images obtained with our first home built prototype are also reported. PMID- 6927208 TI - NMR relaxation of protons in tissues and other macromolecular water solutions. AB - Nuclear magnetic resonance (NMR) longitudinal (T1) and transverse (T2) relaxation parameters have been evaluated for protein solutions, cellular suspensions and tissues using both data from our laboratory and the extensive literature. It is found that this data can be generalized and explained in terms of three water phases: free water, hydration water, and crystalline water. The proposed model which we refer to as the FPD model differs from similar models in that it assumes that free and hydration water are two phases with distinct relaxation times but that T1 = T2 in each phase. In addition there is a single correlation time for each rather than a distribution as assumed in most other models. Longitudinal decay is predicted to be single exponent in character resulting from a fast exchange between the free and hydration compartments. Transverse decay is predicted to be multiphasic with crystalline (T2 approximately 10 microseconds), hydration (T2 approximately 10 msec) and free (T2 approximately 100 msec) water normally visible. The observed or effective transverse relaxation times for both the hydration and free water phases are greatly affected by the crystalline phase and are much shorter than the inherent relaxation times. PMID- 6927209 TI - Transdermal scopolamine in motion sickness. AB - Motion sickness is a common clinical malady. Until recently, the use of scopolamine, the drug of choice for the treatment of motion-induced nausea and vomiting, has been sometimes associated with a variety of unacceptable side effects. These side effects could result from the unpredictable blood levels attained with oral dosage (pulse delivery). A new system of drug delivery, the transdermal therapeutic system (TTS)--Transderm-V--has been developed. The TTS delivers scopolamine across the skin at a constant rate. This permits a drug with a very short half life to be administered over prolonged periods, thereby maintaining blood concentrations at the defined therapeutic level. This precludes the necessity for frequent dosing and increases patient acceptability and compliance while minimizing the untoward effects associated with conventional dosage forms of the drug. PMID- 6927210 TI - Variation in postoperative analgesic requirements in the morbidly obese following gastric bypass surgery. AB - Patient-controlled analgesia is a relatively new method of administering intravenous narcotics for postoperative pain relief. The technique involves the self-administration of a given analgesic in a bolus dose with the aid of a timed infusion and sequencing device. Ten morbidity obese patients undergoing elective gastric bypass surgery were treated in a prospective, unblinded, pilot project to evaluate the efficacy of patient-controlled analgesia. Analgesic therapy was satisfactory in all patients. The mean total dose of morphine sulfate administered during the first 36 hours postoperatively was 66 mg, an average of 1.7 mg/hr. There was a tenfold variation (17.5-175 mg) in the 36 hr total dose. The total dose was not related to body surface area, age, sex, dose per injection, or anesthetic agent. The large variation in individual narcotic analgesic requirements could be a major factor in the suboptimal management of postoperative pain with conventional dosing. Patient-controlled analgesia may circumvent these problems. PMID- 6927211 TI - Cavernous hemangioma of the optic disc. AB - Cavernous hemangioma of the optic disc and retina is a vascular hamartoma composed of clusters of thin-walled saccular aneurysms partially filled with dark venous blood. It is now considered a neuro-oculo-cutaneous syndrome whose mode of inheritance is probably autosomal dominant. This report describes a cavernous hemangioma of the optic disc in a patient without skin or neurological findings. Its clinical appearance, generally benign ocular nature, and occasional association with central nervous system or cutaneous lesions is emphasized. PMID- 6927212 TI - Traumatic bilateral homonymous hemianopic scotomas. AB - A patient is presented who received a gunshot wound that injured both occipital poles. It resulted in a central scotoma that was due to the combined effect of both right and left homonymous hemianopic scotomas. A 15 degrees wedge of retained, functioning, central field permitted the retention of 20/20 visual acuity. This case illustrates the point that only a small portion of the central fixation area need to be retained in order to maintain normal central visual acuity. We stress the diagnostic significance of vertical steps demonstrated with central scotomas as an indication that the field defect is due to retrochiasmal disease rather than bilateral macular or optic nerve disease. PMID- 6927214 TI - Spasm of the near reflex. AB - Four patients with spasm of the near reflex are described. This entity is characterized by transient attacks of convergence, accommodation, and miosis, and is usually seen in young individuals as a functional disturbance. This disease has to be differentiated from other horizontal gaze disturbances, including sixth nerve palsy, divergence paralysis, and insufficiency. Despite extensive investigations, no central nervous system disease was found. PMID- 6927215 TI - Bullous keratopathy accompanying essential iris atrophy: response to lowered intraocular pressure. AB - We present a patient with essential iris atrophy who was normotensive and yet had corneal edema and bullous keratopathy which cleared upon lowering the intraocular pressure. It is proposed that in this patient the endothelial functional status was so compromised that it could not handle the amount of fluid driven into the cornea by a normal intraocular pressure. A more favorable balance between intraocular pressure and endothelial functional status was obtained by lowering the intraocular pressure with acetazolamide and timolol. PMID- 6927216 TI - Eye pain due to carotid stenosis. AB - A 63-year-old woman presented with the acute onset of right eye pain. Ophthalmic and neurologic examinations were normal except for a loud right carotid bruit. Directional Doppler examination suggested a critical stenosis of the internal carotid artery. Subsequent arteriography revealed a 95% stenosis. The eye pain ceased following carotid endarterectomy. PMID- 6927213 TI - Familial pseudotumor cerebri and the empty sella syndrome. AB - The empty sella syndrome may be a later complication of pseudotumor cerebri, based on the relationships of clinical features of both and their visual complication. Pseudotumor cerebri may follow a genetic predisposition but further research is needed to confirm this. PMID- 6927217 TI - Nonfatal maxillocerebral mucormycosis with orbital involvement in a dehydrated infant. AB - Mucormycosis in infants is exceedingly rare, and over 90% of reported cases have been fatal. A case of a dehydrated three-week-old infant with involvement of the palate, maxilla, orbit, and brain is described with extensive laboratory and radiological investigation. This infant survived after surgical debridement and therapy with amphotericin B. PMID- 6927218 TI - Surgical specimens in open angle glaucoma. PMID- 6927222 TI - Enzyme-linked immunosorbent assay for the detection of antibodies to type-B influenza virus. AB - The Enzyme-Linked Immunosorbent assay (ELISA) has been applied to the detection of antibodies to type B influenza virus. The specificity, the sensitivity and the reproducibility of the indirect method has been evaluated. The Haemagglutination inhibition assay (HAI) was used as reference system. The results obtained at a single serum dilution show good correlation between ELISA and HAI test (r = 0.70). Reproducibility is satisfactory. Our results seem to show a better sensitivity of the ELISA test as compared to the HAI test. This feature may be useful for certain applications such as the detection of antibody responses after vaccination. The need of accurate standardization in carrying out the test is pointed out. PMID- 6927221 TI - [2 cases of colitis caused by Clostridium difficile during antibiotic therapy]. AB - Defined the most important clinical, endoscopic and pathological aspects of antibiotic-associated colitis, the AA. examine the Clostridium difficile as the etiological agent. The range of examination has been limited to two cases of pseudomembranous colitis, a diagnostic and a therapeutic evaluation is suggested for patients with AAD and PMC. Furthermore the importance of a strictly observance of hospital hygienic rules in the prevention of such pathological cases is strongly stressed. PMID- 6927220 TI - Presence of circulating immune complexes in patients with chronic lymphocytic leukaemia. Correlations between clinical and immunological features. AB - The presence of circulating immune complexes (CIC) was evaluated in 60 untreated patients with chronic lymphocytic leukaemia with the polyethylene-glycol precipitation assay. The mean values of optical density (OD) in patients' sera was 0.161 +/- 0.121 compared with control values of 0.082 +/- 0.045 (P less than 0.001). Sera of 16 patients gave OD values higher than 0.172 (mean of controls plus 2 SD) and were considered positive for the presence of CIC. Using the new staging proposed by Binet for CLL we did not find any correlation between presence of CIC and stage of the disease. On the contrary, it was possible to correlate the presence of CIC with the stability of the disease: CIC were found in only 2 of the 22 patients (9.1%) with progressive disease but in 10 of the 30 patients (33.3%) with stable disease (P less than 0.05). CIC were present in 12 of the 38 patients in whom the only surface immunoglobulins present were IgM, but in only 1 of the 14 patients in whom both IgM and IgD were contemporaneously present on the lymphocyte surface. No correlations were found between levels of serum immunoglobulins and presence of CIC. PMID- 6927219 TI - A case of sympathetic uveitis. AB - A 38-year-old man developed sympathetic uveitis on the 26th day after his injury. Heavy systemic corticosteroid therapy did not work well at the early stage. Enucleation was not carried out, and systemic and local steroid therapy were continued persistently. In the fourth month after the onset, visual acuity of the sympathized eye returned abruptly to a normal level. In this case, the mechanism of the abrupt recovery is probably spontaneous improvement, and this case alerts the clinician that the enucleation of the injured eye should seldom be performed even if heavy doses of corticosteroid do not work well at the early stage. PMID- 6927223 TI - Prevalence of some markers of the hepatitis B virus in a blood donor population. AB - Investigations were made for anti-HBs and anti-HBe antibodies, markers of hepatitis B virus, in a population of HBsAg negative blood donors, but exhibiting high serum transaminase (ALT) values. 25.9% of this population was found to be positive for at least one type of marker antibody. The samples found to be positive only for anti-HBe were examined for anti-HBc antibodies. These donors were re-examined over a period of time until the anti-HBs antibodies disappeared. Further studies will have to be carried out in order to verify whether those samples of blood found to be positive for anti-HBc and/or anti-HBe are really infecting. The advisability of a systematic ALT activity check in all blood donors is stressed. PMID- 6927224 TI - [Specificity of IgM antibodies detected in human hydatid infection]. AB - Preliminary experiments were performed in order to identify specific IgM antibodies in human hydatid disease by E.L.I.S.A. method with peroxidase conjugated anti-human IgM antibodies. PMID- 6927225 TI - [Identification of 46 yeasts from a clinical source: morphological criteria, biochemical and immunological tests]. AB - From clinical specimens (urine, pharyngeal and vaginal exudates, sputum and skin) 46 yeasts have been identified. The cultures have been divided into 3 groups, according to their morphological characters: unicellular, yeasts having hyphae, pseudohyphae, blastospores and yeasts producing also arthrospores. Tests for fermentation and assimilation of carbohydrates have been employed for S.cerevisiae, T.cutaneum and T.glabrata. By the agglutination tests with monospecific antisera, 40 strains of Candida spp. and T.glabrata are identified; this method was able to differentiate 2 C.stellatoidea from C.albicans group B and 4 C.tropicalis from C.albicans group A. The immunologic method proved highly valuable and practical. PMID- 6927226 TI - Yersinia enterocolitica and eye infection: a case report. AB - The authors reported a culturally proven case of orbital cellulitis, uveitis and conjunctivitis due to Yersinia enterocolitica serotype 0:9. This case, in addition to the previously reported, remarks the importance of Yersinia enterocolitica as ocular pathogen. PMID- 6927227 TI - Evaluation of a commercially available Campylobacter fetus subsp. jejuni antigen in the serologic diagnosis of Campylobacter enteritis. PMID- 6927229 TI - [Therapy of cholera]. PMID- 6927230 TI - [Echocardiographic diagnosis of mitral insufficiency as a consequence of mitral valve cord rupture]. PMID- 6927228 TI - [Modern aspects in the prevention and control of cholera]. PMID- 6927231 TI - [Dissemination of intestinal parasites in school children in Cuprija and surrounding towns]. PMID- 6927232 TI - [Dissemination of intestinal parasites in school children in Veliko Gradiste and Golubac]. PMID- 6927235 TI - [Man between hope and peril in modern medicine]. PMID- 6927236 TI - [Problems in the surgery of cerebral glioma]. PMID- 6927234 TI - [Epidemiology of allergic diseases in Yugoslavia]. PMID- 6927237 TI - [Proteins and protein hormones of the placenta in high-risk pregnancy. Experimental and clinical study]. PMID- 6927233 TI - [The effect of a combination of INH, Rifadin and Miambutol in generalized tuberculosis]. PMID- 6927238 TI - [The pathogenesis and clinical picture of cholera]. PMID- 6927239 TI - [Bacteriologic diagnosis of Vibrio cholerae]. PMID- 6927240 TI - [Present trends in cholera and changes in cholera vibrios]. PMID- 6927241 TI - Thoughts on the emergence of the sense of self, with particular emphasis on the body self. AB - In trying to trace the emergence of the sense of self during the first fifteen months of life--in particular the formation of the bodily self--we used, on the one hand, severe dissociations of the integral parts of the body self such as occurs in psychosis, in the Gilles de la Tourette syndrome, and in phantom-limb disturbances and, on the other hand, data from our normative study of the separation-individuation process as inferred from mother-infant interaction in general and the infant's behavior in front of the mirror in particular. The infant's behavior in front of the mirror strongly suggests that feelings about himself only gradually become integrated with perceptual and cognitive awareness of himself. All the data, furthermore, indicate that it is not possible to study the development of the self separate from the development of the object. All inferences contained in our paper about the emergence of the sense of self were made from the point of view of the central organizing, integrating, and synthesizing institution of the mind, that is, the ego. We agree with other authors that the developing self has both experiential and structural aspects. We titled our paper "Thoughts on the Emergence of the Sense of Self" to indicate that this paper is meant to be an initial and quite tentative communication about the vast and elusive area of personality development concerning the emergence of our bodily self, and thus of the core of our personal identity. PMID- 6927242 TI - The alternate schools and the self. AB - While Adler, Jung, Horney, and Sullivan varied in their definitions of the self played a central role in their theories. The alternate schools all refer to the subjective, creative, experiencing aspects of the psyche in their concepts of self. The thinking of scientists is intimately connected with their personality. The shape their theories take often can be shown to have connections with their early life. An attempt is made to illuminate the contributions made to Jung's theories by the circumstances of his early life. PMID- 6927243 TI - The self psychoanalytic theory. PMID- 6927244 TI - Self, ego, affects, and drives. AB - I have explored the concepts of self, ego, affects, and drives, with special emphasis on terminological confusions and Freud's use of Selbst and Ich. I have also proposed a modification of the dual instinct theory in the light of the relation between affect and drives. Finally, I have proposed a developmental model on the basis of all the above considerations, and stressed its relevance for the classification of nonorganic psychopathology. PMID- 6927245 TI - The self as fantasy: fantasy as theory. PMID- 6927246 TI - The superordinate self in psychoanalytic theory and in the self psychologies. AB - The concept of the self has been used in several attempts to resolve the epistemological problems of what is subjective and what is objective, what is personal and what is organismic. In addition, it has been used to mediate between the hermeneutic and natural-science approaches to psychoanalytic explanation, between the motivational and causal dimensions of our theory and experience. In the case of Kohut, the self was initially invoked to deal with clinical difficulties associated with the analysis of patients with narcissistic personality disorders more recently, it has become the central article in a "self psychology" that addresses presumed deficiencies in the traditional psychoanalytic picture of psychopathology. But the concept of the self is not suited to be a panacea for resolving theoretical or clinical difficulties. The self as person refers to an entity that is both enduring and changing; it describes continuity in the face of change and change in the face of continuity. Abend (1974) comes closest to capturing this attribute of the self in his image of the tidal beach with a configuration that changes but an essence that remains the same. Eisnitz (1980) evokes something similar in his figure-ground conception of the self-representation. The crux of the matter is that the notion of self experience includes a variety of phenomena that cannot be contained within a single self-construct--be it normal pathologic, grandiose, or otherwise. As a result of these considerations, I have argued against the use of the self as a superordinate concept in psychoanalytic theory and have focused on the shortcomings of three self psychologies that use the self in this way. I believe that Klein, Gedo, and Kohut all offer the self as a kind of conceptual tranquilizer for the philosophical, theoretical, and clinical dualities that are inherent in psychoanalytic work. Grossman addressed himself to these dualities as far back as 1967 and elaborated on the problems with Simon (1969) in a pathbreaking paper on anthropomorphism in psychoanalysis. Grossman and Simon contended that the controversy about anthropomorphism in psychoanalytic theory pertains to the basic confusion in psychology between meaning and causality. They submitted that until this confusion was dispelled and until some superordinate concept was found that could "encompass both kinds of discourse", attempts to transform psychoanalysis into a general psychology would result in failure.(ABSTRACT TRUNCATED AT 400 WORDS) PMID- 6927247 TI - Theories of the self and psychoanalytic concepts: discussion. PMID- 6927248 TI - Neurologic, psychiatric, and cardiovascular complications in children struck by lightning. AB - The neurologic changes following lightning injury include coma with cerebral edema, inappropriate secretion of antidiuretic hormone (ADH), seizures, cerebellar ataxia, and painful sensory disturbances. Deteriorating neurologic status may warrant the use of intracranial pressure monitoring devices. Myocardial injury and transient hypertension are generally evident at the onset. Monitoring of the cardiac rhythm may be needed for as long as a week for late onset arrythmia. Abnormalities of memory, mood, and affect noted on recovery of consciousness may persist for months, necessitating close psychiatric and neurlologic follow-up. PMID- 6927249 TI - [4th Congress of Yugoslav Hematologists and Transfusologists. Belgrade, 1982 Abstracts]. PMID- 6927250 TI - Principles of rational classification and nomenclature of human influenza A viruses. AB - To eliminate possible mistakes in the new nomenclature of influenza A viruses, approved by the WHO influenza experts Committee on February 1980, it is suggested to introduce the following changes: reestablish the independent position of subtypes of human influenza A viruses with hemagglutinins HSw1, HO and H1 and neuraminidase N1; use as a principle method for differentiation of various subtypes the hemagglutination inhibition (HI) test instead of the double immunodiffusion test (DIDT); to strengthen the leading role of the host in the classification of influenza A viruses by presenting human influenza viruses separately from the animal and avian viruses; it is advisable to change the present classification of influenza viruses by dividing the family of orthomyxoviridae into two species - Influenza A virus and Influenza B virus and promoting the existing influenza A virus subtypes into the rank of a serotype and the main antigenic variants within each type - into subtypes. PMID- 6927251 TI - Comparison between the complement fixation test LBCF-H100-TTE, IHAT and IgM-IFAT performed on pure IgM fractions in acute acquired and congenital toxoplasmosis. AB - The use of a gel filtration method allowed us to obtain pure IgM fractions to be tested for specific Toxoplasma serology. The good correlation found in our series between IgM-IFAT and LBCF-H100-TTE performed on pure IgM fractions suggests that LBCF-H100-TTE may be another useful serological test for detection of IgM antibodies although false negative results might occur when LBCF-H100-TTE is performed on IgM fractions of cord sera. PMID- 6927252 TI - [Epidemiological results in recovered cases of viral hepatitis at the Infectious Disease Clinic of the University of Perugia from 1971 to 1978]. AB - A retrospective epidemiological survey on patients admitted for hepatitis to the Infectious Disease Institute of Perugia University was undertaken. 255 out of 610 patients, examined during the 1971-1978 period, had type B hepatitis. The incidence of post transfusional hepatitis was 15.7%, while the disease showed significant increase in drug addict patients and in hospital staff. HBsAg was positive in 40 of 94 patients (43.7%) with post-transfusional hepatitis. PMID- 6927254 TI - [Pregnancy and diabetes]. PMID- 6927253 TI - [The heart and diabetes]. PMID- 6927257 TI - [Brittle diabetes. Report on certain aspects through a study of 762 patients]. PMID- 6927255 TI - [Our management of pregnancy in diabetics]. PMID- 6927256 TI - [The epidemiology of diabetes in the population of Tunis. A representative sample]. PMID- 6927258 TI - [The eye and diabetes]. PMID- 6927259 TI - [The diabetic kidney]. PMID- 6927260 TI - Lasers in ophthalmology. PMID- 6927261 TI - The effects of famine on brain growth in children. PMID- 6927264 TI - Medical aspects of life insurance. Medicine & life assurance. PMID- 6927263 TI - Cerebral vascular disease. PMID- 6927262 TI - Modern trends and vascular disease. Peripheral arterial disease. PMID- 6927266 TI - An underwriter's view. PMID- 6927269 TI - The price of health. PMID- 6927268 TI - Update on apudomas. PMID- 6927267 TI - Annual oration on leadership in medicine. PMID- 6927265 TI - Permanent Health Insurance. PMID- 6927271 TI - 'New light on the inner man'--the contribution of colonoscopy to modern medical practice. PMID- 6927272 TI - The hand in dermatology. PMID- 6927270 TI - Nuclear magnetic resonance. Its clinical application. PMID- 6927273 TI - The hand in neurological diagnosis. PMID- 6927276 TI - 'Canberra' (role conversion) triage and resuscitation. PMID- 6927277 TI - Ajax Bay. PMID- 6927275 TI - Naval medicine in the Falklands Conflict April-July 1982. Overall policy and operations. PMID- 6927274 TI - Regulation of the self in adolescence with particular reference to anorexia nervosa. PMID- 6927278 TI - 'SS Uganda'--surgery in the hospital ship. PMID- 6927279 TI - Ophthalmology. Recent advances in cataract surgery. PMID- 6927280 TI - Rapidly growing mycobacteria: testing of susceptibility to 34 antimicrobial agents by broth microdilution. AB - A total of 18 strains of Mycobacterium fortuitum, 15 strains of M. chelonei, and 31 strains of M. chelonei-like organisms were tested by both broth microdilution and agar dilution to determine their susceptibility to 34 antimicrobial agents. All strains grew well enough in cation-supplemented Mueller-Hinton broth for endpoints to be read after 72 h of incubation. Some strains of M. chelonei did not grow on Mueller-Hinton agar. A few discrepancies were noted between the broth and agar procedures. For M. fortuitum, doxycycline, minocycline, amikacin, sulfamethoxazole, and sulfamethoxazole-trimethoprim were the most active agents. For M. chelonei, amikacin, sisomicin, tobramycin, and erythromycin were the most active agents. The M. chelonei-like organisms were most susceptible to ampicillin, doxycycline, minocycline, amikacin, erythromycin, sulfamethoxazole, and sulfamethoxazole-trimethoprim. Broth microdilution appears to be a reliable method for susceptibility testing of rapidly growing mycobacteria, although clinical studies are needed to determine how well in vitro results correlate with therapeutic in vivo outcome. PMID- 6927281 TI - Penetration of moxalactam and cefazolin into atrial appendage after simultaneous intramuscular or intravenous administration. AB - This study compared the penetration of moxalactam and cefazolin into the human atrial appendage after simultaneous administration of both drugs by two routes. Nineteen adult patients scheduled for coronary vein bypass surgery randomly received 10 mg of moxalactam and cefazolin per kg by either the intramuscular or intravenous (bolus) route on administration of anesthesia. Concentrations of cefazolin in serum were significantly greater than concentrations of moxalactam at all times for both routes of administration. There were no significant differences, however, in the concentration of these drugs in atrial appendages, although concentrations of both agents administered intravenously were significantly greater than of drugs administered intramuscularly. (19.3 +/- 10.3 and 21.0 +/- 11.0 micrograms intravenously versus 8.3 +/- 3.6 and 10.1 +/- 3.2 micrograms/g intramuscularly for moxalactam and cefazolin, respectively). PMID- 6927282 TI - Pharmacokinetics of the cephalosporin SM-1652 in mice, rats, rabbits, dogs, and rhesus monkeys. AB - The pharmacokinetics of SM-1652 were studied in mice, rats, rabbits, dogs, and rhesus monkeys. The plasma half-lives of SM-1652, administered intravenously at a dose of 20 mg/kg, were 11.0 min in mice, 26.0 min in rats, 65.8 min in rabbits, 72.6 min in dogs, and 150.9 min in monkeys. The 24-h urinary excretion of SM-1652 was 30 to 35% of the dose in mice and rats, 70 to 75% in rabbits and dogs, and 45% in monkeys. Biliary excretion of the antibiotic over a 24-h period was 60 and 19% in rats and rabbits, respectively; it was 19% in dogs over a 9-h period after SM-1652 administration. Approximately 95% of the intravenous dose of SM-1652 was recovered as the unchanged form in the urine and bile of rats and rabbits. The binding of SM-1652 to serum protein was 44.0% in mice, 46.0% in rats, 90.4% in rabbits, 93.2% in monkeys, 30.0% in dogs, and 96.3% in humans. PMID- 6927284 TI - Impact of cefoperazone therapy on fecal flora. AB - To evaluate the effects of parenteral cefoperazone therapy upon human fecal flora, fecal specimens obtained from four patients before and during therapy (as well as after therapy for one patient) were cultured quantitatively for facultative, aerobic, and anaerobic bacteria and for fungi. Cefoperazone therapy was associated with major changes in fecal flora. There was suppression to undetectable levels or an appreciable reduction in all anaerobic bacteria as well as suppression of all initially detected Enterobacteriaceae. During therapy, there was acquisition or an increase in counts of Candida spp., so that these became the most numerous fecal microorganisms in all patients. In addition, Pseudomonas spp. and coagulase-negative Staphylococcus sp. were acquired by three patients. These marked alterations in flora have potentially important consequences. PMID- 6927283 TI - Antimicrobial susceptibility of Streptococcus pneumoniae: serotype distribution of penicillin-resistant strains in Spain. AB - This study examined the resistance to penicillin, tetracycline, erythromycin, and chloramphenicol of 318 pneumococcal strains isolated in Spanish hospitals from blood or cerebrospinal fluid of patients during 1979 to 1981. The serotypes of these strains were determined to discover whether a correlation between serotype and patterns of antibiotic resistance could be found. Seven and nine patterns of resistance were found in strains isolated from blood and cerebrospinal fluid, respectively; tetracycline was the most frequent pattern, followed by tetracycline associated with chloramphenicol. A random distribution of serotypes which was similar to the general distribution of serotypes was found for resistance to tetracycline and chloramphenicol, but penicillin-resistant strains were confined to seven serotypes. Thirty-six strains of penicillin-resistant pneumococci isolated from sources other than blood or cerebrospinal fluid were also serotyped. They represented the same serotypes, suggesting that serotype distribution among penicillin-resistant strains could be a manifestation of local epidemiological factors. PMID- 6927286 TI - Antiviral activity of sodium 5-aminosulfonyl-2,4-dichlorobenzoate (M12325). AB - Sodium 5-aminosulfonyl-2,4-dichlorobenzoate (M12325) was evaluated for antiviral activity in tissue culture and infected mice. At concentrations ranging from 2.5 to 75.8 micrograms/ml, M12325 inhibited the cytopathic effects of 10 mean tissue culture infective doses of influenza virus A/WSN, A/FM, A/Kumamoto, and B/Great Lakes; parainfluenza virus; rhinovirus; echovirus; respiratory syncytial virus; and vesicular stomatitis virus. Concentrations up to 150 micrograms/ml did not inhibit the cytopathic effects of herpes simplex virus, vaccinia virus, or adenovirus. Concentrations up to 3,160 micrograms/ml did not inhibit the growth of MDCK, Vero, or HEL cells in culture. Single oral doses of M12325, ranging from 10 to 300 mg/kg, administered 1 h before and 1 h after challenge, reduced mortality in mice inoculated intranasally with influenza A/WSN virus. Twice daily oral doses for 14 days effected significant reductions in the mortality of mice infected intranasally with influenza A/WSN, A/FM, A/Kumamoto, and B/Great Lakes, and parainfluenza virus, but they were not effective in mice infected with herpes simplex virus. Multiple doses of 10 and 30 mg/kg, administered intraperitoneally, reduced lung consolidation and virus titer. M12325 was well tolerated in multiple doses up to 1 g/kg orally. These observations support the conclusions that M12325 has a broad spectrum of activity against RNA viruses in vitro and in vivo, selective toxicity, and a large margin of safety. PMID- 6927285 TI - Ribosomal resistance in the gentamicin producer organism Micromonospora purpurea. AB - The mechanism of resistance of the gentamicin-producing organism Micromonospora purpurea was analyzed. Determination of minimal inhibitory concentrations revealed high resistance to the 4,6-substituted deoxystreptamine aminoglycosides amikacin, gentamicin, kanamycin, netilmicin, sisomicin, and tobramycin and also to lividomycin A and hygromycin B, but susceptibility to streptomycin, dihydrostreptomycin, paromomycin, and neomycin during all phases of the growth cycle. The nonproducing, closely related Micromonospora melanosporea was susceptible to these compounds. In agreement with results from previous studies (R. Benveniste and J. Davies, Proc. Natl. Acad. Sci. U.S.A. 70:2276-2280, 1973), extracts from M. purpurea showed no activity of enzymes specifically modifying gentamicin. 70S ribosomes from M. purpurea but not from M. melanosporea were resistant to inhibition by gentamicin, kanamycin, tobramycin, and lividomycin in a polyuridylic acid-dependent polyphenylalanine synthesis system and susceptible to those compounds which were inhibitory in vivo. The former antibiotics were also unable to induce misreading. Subunit exchange experiments between M. purpurea and M. melanosporea showed that the main site for inhibition and induction of misreading is the 30S subunit (up to gentamicin concentrations of 10 micrograms/ml). PMID- 6927287 TI - Excretion of cephalothin and cefamandole by the normal pancreas and in acute pancreatitis in dogs. AB - Nine mongrel dogs were studied to evaluate the excretion of cefamandole (five dogs) and cephalothin (four dogs) in the pancreatic fluid. Each dog was studied before and after the induction of pancreatitis, with 2 weeks between studies. After intravenous administration of a 25-mg/kg dose of either cephalosporin, serum and pancreatic fluid concentrations were monitored for 6 h. Both cephalothin and cefamandole were excreted in bactericidal concentrations in the normal pancreas and in acute pancreatitis. Clearance of cefamandole (290 ml/min) and cephalothin (348 ml/min) were similar pre- and postinduction of pancreatitis. Serum albumin concentration was less during the post-pancreatitis phase compared with the prepancreatitis phase. Penetration of cephalothin was reduced in pancreatitis, whereas cefamandole penetration increased in pancreatitis. PMID- 6927288 TI - Comparative in vitro activities of niridazole and metronidazole against anaerobic and microaerophilic bacteria. AB - In vitro susceptibilities of anaerobic bacteria (Bacteroides spp., Fusobacterium spp., Clostridium spp., and Peptococcus sp.) and of Campylobacter jejuni and C. coli to niridazole and metronidazole were determined. The minimum inhibitory concentrations for niridazole ranged from 0.0037 to 1.0 microgram/ml and, for metronidazole, from 0.25 to 128 micrograms/ml. PMID- 6927289 TI - In vitro activity of pipecolic acid amide of clindamycin (U-57930E) on anaerobic bacteria compared with those of clindamycin, cefoxitin, and chloramphenicol. AB - In vitro activity of pipecolic acid amide of clindamycin (U-57930E) against 265 isolates of anaerobic bacteria, including 66 strains of Bacteroides fragilis, was compared with those of clindamycin, chloramphenicol, and cefoxitin. At therapeutically achievable concentrations, the activities of all four antibiotics against anaerobic bacteria were similar. PMID- 6927290 TI - [Congenital disorders of hemostasis. Diagnosis and treatment]. PMID- 6927291 TI - [Acquired disorders of hemostasis. Diagnosis and treatment]. PMID- 6927292 TI - [Replacing the administration of whole blood with blood derivatives]. PMID- 6927293 TI - [Aplastic anemia]. PMID- 6927294 TI - [Rational diagnosis of anemia]. PMID- 6927295 TI - [Morphologic diagnosis of leukemia]. PMID- 6927296 TI - [Differential diagnosis of enlarged lymph glands in children]. PMID- 6927297 TI - [Diagnosis of malignant lymphoma]. PMID- 6927298 TI - [Rational diagnosis and therapy of anemia in children]. PMID- 6927299 TI - Comparison of surface iodination methods by electron microscopic autoradiography applied in vitro to different life-stages of Dipetalonema viteae (Filarioidea). AB - Different states of Dipetalonema viteae (males, females, microfilariae, and 3rd stage larvae) have been iodinated in vitro under physiological conditions by chloroglycoluril, lactoperoxidase or chloramine T. The concentrations of the catalysts were correlated with the viability of the worms. Localization of the label with the different iodination methods had been visualized by electro microscopical autoradiography. Chloroglycoluril-mediated iodination is predominantly localized on the filarial cuticle. Lactoperoxidase-catalysed iodination is less specific and chloramine T catalyses iodination in a gradient decreasing from the cuticle to inner structures. It is necessary to visualize the labelling by electron microscopical autoradiography prior to biochemical and immunological experiments to avoid the extraction of structures iodinated by leakage of the catalyst into sub-cuticular regions. PMID- 6927300 TI - [Derivatives of 4-phenylcyclohexylethylamine with antidepressive activity]. AB - Several new derivatives of trans-1-(4-phenylcyclohexyl)-ethylamine (M.G. 6669) have been synthesized with various substituents at the alpha-carbon and/or at the amine nitrogen atom. All compounds were evaluated for a potential antidepressant activity taking M.G. 6669 as reference. They turned out to be less active than the reference substance. Pharmacological evaluation of M.G. 6669 itself was broadened during this work. The good antidepressant properties of this compound were confirmed, accompanied however by some toxic phenomena. PMID- 6927302 TI - The future for recombinant DNA in medicine: potential for treating genetic diseases. PMID- 6927301 TI - [Comparison of the anticonvulsant and central effects of 3-bromophenylsuccinimide and N-methylimide of 3,5-dibromophenylsuccinic acid]. PMID- 6927303 TI - [Outcome of obstetric fractures of the forearm]. PMID- 6927307 TI - Twin transference as a compromise formation. AB - This paper explores the meanings and functions of a transference paradigm of a fantasied twin relationship with the analyst. Twin transference in the analysis of nontwins has been reported infrequently in the psychoanalytic literature, except recently by Kohut and his co-workers, who refer to twinship transference as a variant of narcissistic mirror transference. We suggest that such narrow definition tends to reduce the complexity of the wish for a twinlike relationship with the analyst. Analytic data are used to show the advantages of examining twin transference within structural theory, in terms of the multiple functions served by this rather primitive transference paradigm, rather than reducing it only to one variant of the need for certain mirroring functions. We suggest that twin transference, together with all twin fantasies, subserves multiple functions, of which we highlight gratification and defense against the dangers of intense object need. In this formulation, the twinlike representation of the object provides the illusion of influence or control over the object by the pretense of being able to impersonate or transform oneself into the object and the object into the self. Intense object need persists together with a partial narcissistic defense against full acknowledgment of the object by representing the sought after object as combining aspects of self and other. Further analytic attention needs to be directed to the specific representation of the needed object in certain primitive transference paradigms instead of exclusive emphasis on the functions required of the object. Our analytic data are used to argue that intense early needs of an object are best understood analytically within a conflict model in which they are modified by multiple wishes, drives, fears, dangers, and needs for defense. PMID- 6927306 TI - [Surgery of hypertrophic subaortic stenosis: long-term results]. PMID- 6927304 TI - Preoperative transfusion of vinblastine-treated platelets before splenectomy indicated for immunothrombocytolytic purpura. PMID- 6927308 TI - Effects of atropine, pilocarpine and morphine on footshock-induced aggressive behaviour in rats after lesion of hippocampal pyramidal cells with kainic acid. PMID- 6927305 TI - View from the Nation's Capitol. PMID- 6927310 TI - [Success and failure in the surgery of urinary incontinence]. PMID- 6927311 TI - [Chain urethrocystography in the evaluation of stress urinary incontinence]. PMID- 6927309 TI - [Gravidic pruritic urticarial papules and plaques]. PMID- 6927312 TI - [Stress urinary incontinence. Physiopathology]. PMID- 6927314 TI - [Advances in the pathogenesis of hydatidiform mole]. PMID- 6927313 TI - [Pituitary microadenoma. Subsequent pregnancies (clinical cases)]. PMID- 6927315 TI - [Amniotic fluid drainage following amniocentesis]. PMID- 6927317 TI - [Epidemiology of uterine cervix cancer]. PMID- 6927318 TI - [Round table: Carcinoma of the cervix uteri]. PMID- 6927320 TI - [Ultrasonic treatment for cyclic breast discomfort]. PMID- 6927321 TI - [Current status of vaginal hysterectomy. Experience of 5 years]. PMID- 6927316 TI - [Fertility after conization of the uterine cervix]. PMID- 6927322 TI - Diurnal rhythms in macular degeneration. AB - A retrospective clinical study on the sleeping habits of patients with macular degeneration was conducted to test the hypothesis that alterations in cone outer segment shedding cycles might be important in the pathogenesis of this disease. No significant difference in number of hours of sleep per night, frequency of nighttime awakening, or frequency of daytime napping was found between patients with macular degeneration and controls. This finding does not support the hypothesis at this level of inquiry. Because cone outer segment shedding is cyclical, other studies of diurnal rhythms in these subjects may be rewarding. PMID- 6927323 TI - [The pineal gland in isolation stress]. PMID- 6927319 TI - [Clinical and laboratory characterization in 100 cases of pregnancy cholestasis]. PMID- 6927324 TI - [Rotation from a clinical and radiologic point of view in scoliosis of less than 20 degrees]. PMID- 6927325 TI - [Treatment of fractures of the clavicle]. PMID- 6927326 TI - [Cytoarchitecture of the hypothalamus of Pleurodeles waltlii (Michaelis)]. PMID- 6927327 TI - [Histochemical studies of the action of haloperidol and chlorpromazine on GABA transaminase activity in various nerve centers]. PMID- 6927330 TI - [Qualitative and quantitative comparative histologic study of the mesencephalic areas in 4 species of reptiles. I. Somatic, viscero-motor and somatosensory zones]. PMID- 6927328 TI - [Ontogenic study of the structure of the cerebellar structure of Rana ridibunda]. PMID- 6927329 TI - [In vitro cultures of the chick embryo ciliary ganglion in chemically-defined media. I. Effects of hormones and endothelial cell growth supplement]. PMID- 6927331 TI - Brain morphometry applied to the knowledge of the nervous system of vertebrates. I. Study on the hound dog brain. PMID- 6927333 TI - Glutamate dehydrogenase in the postnatal developing cerebellum. A biochemical study. PMID- 6927332 TI - [Innervation and ultrastructure of the ampullae of Lorenzini of the lesser spotted dogfish, Scyliorhinus canicula, L]. PMID- 6927336 TI - [Immunological parameters in subjects with essential arterial hypertension. I. Lymphocyte subpopulations]. AB - Peripheral venous blood lymphocytes were defined, in 21 subjects with essential hypertension and 20 controls, on the basis of reactivity with monoclonal antibodies OKT3, OKT4, OKT8, OK1Ia. Total lymphocyte count, OKT3+ and OKT4+ cells percentage were similar in normal and hypertensive. OKT8+ cells percentage was significantly lower only in hypertensive stage II and III patients (WHO classification). PMID- 6927335 TI - Pharmacology, clinical efficacy, and adverse effects of sucralfate, a nonsystemic agent for peptic ulcer. AB - Sucralfate, a complex salt of polyaluminum hydroxide with a sulfated disaccharide skeleton, has recently been approved by the Food and Drug Administration for the short-term treatment of duodenal ulcer. The drug is nonsystemic in action and apparently exerts its antiulcer effects by bonding with proteinaceous exudates in the ulcer crater, thereby protecting it from insult. In vitro and clinical studies have shown that the drug is not an antacid but does block the diffusion of acid. Inhibition of pepsin and bile acid activities have also been demonstrated. In double-blind clinical trials where patients used antacids as needed for pain, sucralfate 1 g 4 times a day was significantly more effective than placebo and as effective as cimetidine. No serious adverse effects have been caused by this locally-acting agent. PMID- 6927338 TI - Ultrastructure and cytochemistry on old odontoblasts in rat incisors. PMID- 6927337 TI - Scanning immunoelectron microscopic study of normal, inflammed and neoplastic human bladder epithelium. PMID- 6927339 TI - The morphological studies on characteristics of isolated parenchymal and non parenchymal cells of the rat liver. PMID- 6927334 TI - [2-Phenolazoimidazole as chelating agents. II. Analytical investigations of pyrocatecholazo- and resorcinolazobenzimidazole (BIAP, BIAR, BIAREZ-beta)]. PMID- 6927340 TI - High resolution analysis of three-dimensional structure of the Golgi apparatus in rapid-frozen, substitution fixed gerbil sublingual gland acinar cells. PMID- 6927341 TI - Scanning electron microscopy of the pharyngeal floor in the development of rat thyroid gland. PMID- 6927342 TI - An application of the ferrocyanide-reduced osmium tetroxide for the ultrastructural analysis of gerbil Harderian gland. PMID- 6927343 TI - Preservation of catecholamine granules by the fixative containing nitrogen mustard N-oxide. PMID- 6927344 TI - [Problems of the therapy of neonatal convulsions]. AB - The newborn with seizures should be treated urgently, because of the high risk of consequent brain damage. In addition to general management in order to correct metabolic and functional unbalancement, associated with the fits, specific causes of neonatal seizures (hypoglicemia, hypocalcemia, hypomagnesiemia, hypo hypernatremia, pyridoxine deficiency) should be immediately removed. If neonatal seizures depend on other non specific causes (anoxia, cerebral hemorrhagy, malformation, infection or other, a symptomatic anticonvulsant treatment should be carried out without delay. Useful drugs for the newborn are phenobarbital, phenytoin and benzodiazepine e.v. or e.m. After fits have been controlled, an oral maintenance therapy has to be started with phenobarbital or phenytoin in order to avoid seizure-relaps. Clinical EEG and hematological data should be monitored to detect side effects, as well as plasma drugs levels to achieve adequate maintenance doses. Criteria for discontinuing the neonatal seizures treatment have not been well established. On the bases of the data collected through a longitudinal study of 54 newborns who developed seizures in the first day of life, clinical and EEG criteria for discontinuing anticonvulsant therapy are discussed. If the fits are rare, short, immediately controlled and EEG is mildly abnormal, we attempt to discontinuing treatment within 15 days. If fits are unfrequent, varying in length, their therapeutical control is reached within 3 days and the EEG is markedly abnormal but recovered within 1 month, treatment is discontinuing between 15 days and 3 months.(ABSTRACT TRUNCATED AT 250 WORDS) PMID- 6927345 TI - [Bronchopulmonary dysplasia in very low birth weight infants]. AB - The reported incidence of Bronchopulmonary dysplasia (BPD) varies from 5% to 68%. The different criteria used to define BPD are responsable for these discrepancies: some Authors include only patients with a clinical and radiological picture that fits the stage IV, as originally described by Northway, others use a more liberal approach and include all patients with manifestations of chronic pulmonary disease. We observed BPD in 12 of 22 (54%) survivors infants of very low birth weight (mean 1115 gm) and gestational age (mean 29,2 weeks). The infants were all born between November 1979 and March 1981. According to Ehrenkranz et al., we classified the radiological findings as severe, moderate and mild. We believe that the etiology of BPD in very low birth weight infants is multifactorial. However, pulmonary oxygen toxicity and immaturity are the most important causes. PMID- 6927346 TI - [The Emilia-Romagna Abnormalities Study Group: coverage and geographic distribution of congenital abnormalities in Emilia-Romagna]. AB - Systems for monitoring Congenital Malformations (C.M.) have been taken up by most Countries, even though there is great diversity in the methods of data collection. In Italy nothing existed until 1977. In 1978 in the Emilia-Romagna Region an epidemiological Program began for the surveillance and monitoring of all C.M. diagnosed in the first 7 days of life in the newborn babies and in the stillbirths of over 28 weeks of gestational age. After three years of monitoring 1978 to 1980-we have reached the baseline data which is the fundamental prerequisite to ensure comparability of data from different centers and within our region in different periods too. The incidence of all C.M. was 1.9% in the first three years of monitoring with no statistical difference from year to year or between the Districts of the Region. For six selected C.M. we studied the incidence in the Region and also in the four Districts starting from 1978. Our data is comparable to that reported in the other Countries but we observed high incidence of Down Syndrome (17.2 per 10,000 births that is one of the highest values detected = 1 case every 582 newborn babies). For hypospadias we observed, starting from the second quarter of 1980, a progressive increase that dropped however in the first quarter of 1981. No etiologic clues have yet been revealed. PMID- 6927348 TI - [Therapy of bronchospasmic crisis of childhood with aminophylline]. AB - We tested a new product containing aminophylline with 1,56% alcohol as therapy of bronchospasm in childhood to evaluate therapeutic activity, tolerance and adverse reactions. Authors confirm the usefulness of this product in childhood but dosage must be individualized with monitoring of theophylline blood levels. PMID- 6927347 TI - [The VACTERL association and its nosologic limits]. AB - We present six cases of V.A.C.T.E.R.L. association diagnosed by the Study Group of Congenital Malformations in Emilia Romagna (I.M.E.R.) from january 1978 to december 1981. With regard to the etiology, the pregnancy history of these six cases does not support the hypotesis of the progestin-estrogen compounds as possible teratogenic factors of the V.A.C.T.E.R.L. association. Furthermore the familial recurrence hypotesis of this complex needs further detailed studies. At last we attempt to specify the nosological limits of the V.A.C.T.E.R.L. association respect to other similar malformative complexes as the Caudal Regression Syndrome, Rokitansky Syndrome, Holt-Oram Syndrome and Potter Syndrome. PMID- 6927349 TI - [The newborn infant in the Aosta Valley: preliminary statistical analysis of various ethnic and geographic factors]. AB - We have examined 976 new-born babies in Aosta Valley retrospectively, in order to determine which risk factors were significantly linked with the high incidence of: hospitalization and infants with below average neonatal and placental weight. The new-borns of native mothers have been compared with those of immigrant mothers, and also the new-borns of parents living in mountains have been compared with those of parents living in town. Results have shown new-born babies of native mother are at a disadvantage, especially regarding: the neonatal and placental average weight and the incidence of small for gestational age infants (SGA). No statistically significant difference has been found from the geographical point of view. Our results have stimulated a desire for deeper knowledge concerning the ethnical distribution of our neonatal sample and the maternal anamnesis before delivery: these are the two problems we are presently concerning ourselves with. PMID- 6927352 TI - [Turner's phenotype and diagnosis of Noonan's syndrome]. AB - The Authors describe two cases of Noonan's Syndrome (Turner phenotype and normal Karyotype), underlining the necessity of a differential diagnosis with the "True" Syndrome of Turner, for the presence, in the latter, of a non development of the height, weight and phenotype, which moves away from the standard much. While on the contrary in the Noonan's syndrome both the sexual development and the evolution of the height and weight may be normal and in the latter syndrome, so, the attention of the Doctors has to be turned prevalently to the congenital cardiopathy (almost always stenosis of the pulmonary artery), which can also impair the life of the patient. PMID- 6927350 TI - [Drugs administered to the mother during labor and neonatal jaundice]. AB - The authors investigated the relationship between neonatal hyperbilirubinaemia and the administering of drugs to mothers during labor and delivery in 756 A.G.A. regular pregnancy born. Findings point out a statistically significant relationship (P less than 0,05) between all drugs administered to mothers, general anesthesia included, and the presence of jaundice in newborn. Authors recommend administration of drugs to women in labor and in delivery only if strictly necessary. PMID- 6927351 TI - [Increase of IgE in asthmatic children: correlation with eosinophilia, skin tests and the value of the other gamma-globulins]. AB - After considering IgE behaviour in various forms of atopic diseases the authors examine the importance of serum IgE levels in bronchial asthma diagnosis. They herein underline the correlation between IgE and positive skin test, its relationship with other immunoglobulines and its proportional increase to the age of the patient and the eosinophilia. As far as this study is concerned, 91% of asthmatic children register an IgE increase, against 9% only, this being the case of children under three years of age; 91% skin tests are positive and 41% register an increase of IgA, while the eosinophilia is unsignificant. The anamnestic data of atopic dermatitis and asthmatic bronchitis affecting 15 among our patients are found to be of great importance. PMID- 6927353 TI - [Breech presentation: vaginal delivery or elective cesarean section?]. AB - The incidence of asphyxia and mortality has been evaluated retrospectively in 716 breech newborns who were vaginally or by elective caesarean section delivered. In the group of 171 preterm infants the rate of asphyxia and mortality has been more elevated in the newborns vaginally delivered; in the group of 545 term infants has not been any difference between those who were delivered vaginally or by caesarean section. About the 50% of the term infants and only the 8% of the preterm infants were delivered by caesarean section. Consequently, we can deduce that the elective caesarean section would be used also in infants of GA less than or equal to 36 weeks. PMID- 6927354 TI - [Intestinal lymphangiectasis: late complication of transportation of the great vessels corrected by the Mustard technic. A clinical case]. AB - The Great Arteries Transposition corrected by Mustard's repair is often complicated with inferior vena cava obstruction with consequent intestinal lymphangiectasia and protein-losing enteropathy. We report a case of a 9 years old boy who underwent Mustard's repair and presented diarrhoea, abdominal pain, hypoproteinemia and ascites. The fecal elimination of 51Cr-labeled albumin was remarkable increased and the intestinal biopsy showed a noteworthy lymphangiectasia due to an hemodynamic overload. Therefore subjects with Great Arteries Transposition corrected by Mustard's repair should be valued in the post surgical follow-up by 51Cr-labeled albumin fecal elimination and by intestinal biopsy, already sensitive in asymptomatic phase. PMID- 6927356 TI - [Finnish-type nephrotic syndrome: report of the fourth case in Italy and review of the literature]. AB - The Authors have studied anamnestic, clinical and morphological data of a case of Congenital Nephrotic Syndrome of Finnish type (CNS-FT). Similarly to the first case reported in Italy, the patient was born by consanguineous parents. For the determination of the real incidence of this disease, in countries shere CNS-FT is rarely signalled, the importance of histopathological examination of the kidney is emphasized. PMID- 6927359 TI - [Fat necrosis in the newborn infant associated with hypercalcemia and dyslipidemia (description of a case)]. AB - A case of subcutaneous fat necrosis (S.F.N.) with hypercalcemia and hyperlipemia in a newborn infant is reported. On the basis of previous reports it is impossible to definite the pathogenesis of hypercalcemia and hyperlipemia in subcutaneous fat necrosis. Moreover the Authors point out that in a newborn with S.F.N. plasma levels of calcium and lipids and, if it is possible, urinary prostaglandin E and serum PTH and 250HD3 should be determined. PMID- 6927355 TI - [Hypoplasia of intra- and extrahepatic bile ducts associated with congenital abnormalities]. AB - The present report deals with a patient affected by Alagille's syndrome. The clinical hallmark of this syndrome is chronic cholestasis with ductular and extrahepatic hypoplasia and associated multiple congenital malformations. The diagnosis was made by hepatobiliary scanning with TC99-HIDA, transendoscopic cholangiography and liver biopsy. PMID- 6927357 TI - [Congenital dilatation of the choledocus. Diagnostic considerations and therapeutic indications]. AB - From 1964 to 1979, 7 children affected by congenital choledocal cyst were operated on. A cysto-duodenostomy was performed in all cases but one, in whom an excision of the cyst was directly carried on. In the light of the this experience Authors conclude that direct excision is preferable rather than a cysto duodenostomy and furthermore possible to be arrived at basically by means of ultrasound. This latter one is considered so far the best way to reach a pre operative conceptualization of the pathology. PMID- 6927360 TI - [An extreme case of Lobstein's osteopsathyrosis: problems of surgical correction]. AB - Those surgeons who have had experience of Sofield's treatment in case of osteogenesis inperfecta would be unanimous in agreeing that this method offers great advantages to these unfortunate children. Although the technic is exact and the results often cancelled out by the growth so that the re-operation is indicated, nevertheless the long fracture-free period gained and the control of deformity confer very worth-while benefits. A case of O.I. is reported; the subject presented fracture sequaele in the lower limbs and bone alterations of extreme seriousness. Sofield's treatment was not possible in the rodding time; the Authors describe a modified treatment which has proved useful in practice. Notes on the specific features, course and treatment are presented; a particular attention is paid to its genetic and etiopathogenetic aspects. PMID- 6927358 TI - [Severe mental retardation and slight dysmorphism in a child with a bisatellite extrachromosome: inversion duplication (15)?]. AB - A de novo tetrasomy 15 has been reported, in a 6 years old child. The patient had severe mental retardation an minimal physical stigmata, consisting in slight skeletal and facial dismorphism. Cytogenetic analysis showed that extrachromosome, G-like long, was bisatellited and dicentric and was interpreted either as an inversion duplication 15 or as 15; G or D translocation. PMID- 6927361 TI - [Hepatic hemangioma in the neonate: description of a case treated surgically with favorable outcome]. AB - The authors describe a case of hepatic hemangioma in a newborn, treated by successful surgical resection. Neonatal hepatic hemangioma is able to produce congestive heart failure with high output, thrombocitopenia, spontaneous rupture with peritoneal hemorrhage and sudden death. The major symptoms are a palpable anterior abdominal mass, tachicardia, and congestive heart failure unrespansive to medical treatments; sometimes there are cutaneus hemangiomas. When diagnosis is made, surgical resection is necessary in the solitar hemangioma; for diffuse or multinodular hemangiomatosis radiotherapy, corticosteroids and hepaticartery ligation have been employed with some good results. PMID- 6927362 TI - [Chylothorax in a newborn infant]. AB - A case of chylothorax in newborn is described. A the fifteenth day a sudden respiratory distress for chylothorax has appeared. A continuous drainage, after thoracenteses, has been placed; the clinic course has been favourable and, at five day, we have started with MCT feeding. PMID- 6927363 TI - [Mode of action of new antitumor compounds]. AB - The antitumoral agents PR toxin, bouvardin and grandilactones A and B inhibit the growth of HeLa cells, and abolish polyphenylaline synthesis by polyuridylic acid in acellular eukaryotic systemns. However, only bouvardin and the PR toxin inhibit polypeptide synthesis in polysomes using endogenous m-RNA. In addition, grandilactones A and B inhibit the "fragment" reaction, which indicates that they affect specifically peptide bond formation, and the lack of effect on polysomes of these compounds would be due to the fact that, in polysomes, the substrate is bound to either the donor on the acceptor site. Apparently, the PR toxin acts by blocking the enzymatic binding to 80 S ribosomes of (3H)phenylalanyl-tRNA. The inhibitory action of bouvardin seems to be result of the selective blocking of peptidyl-tRNA translocation dependent on elongation factor EF-2 and GTP. PMID- 6927364 TI - [Experimental methodology for the selection of potential anticancer agents]. AB - The authors expose the aims of experimental cancer chemotherapy, describing the procedure they follow to select potential anti-cancer chemotherapy agents, and the further activity and toxicity tests that are necessary before a product can be used in human cancer therapy. PMID- 6927365 TI - [Coordination compounds of Pd(II) with potential antitumor activity]. AB - The first results about the anti-neoplastic activity of Pd(II) ion coordinative compounds with complexones of the ethylenediamine-tetraacetic acid type are described. The assays employing Ehrlich ascites cancer of the mouse show that the presence of substitutes in the ethylenediamine skeleton originates important changes of the activity of such compounds. PMID- 6927366 TI - [Diminution of the rate of growth of HeLa cells caused by thioproline (Tp) and 2 aminothiazoline HCl (2-AT). Effect of L-proline]. AB - Some aspects of the effect of thioproline and 2-amino-thiazoline-HCl on HeLa cell cultures are studied. Both drugs, at 1 mM concentrations, produce morphological changes that become stabilized after four days. The morphology changes depend on the microtubules, microfilaments, and de novo protein synthesis. Both drugs diminish the growth rate of HeLa cells, the effect being partially reverted by high concentrations (2 mM) of L-proline. PMID- 6927367 TI - [Pharmacokinetic study of adriamycin in dogs and rabbits, in the absence of a carrier]. AB - The authors make a pharmacodynamic study about the effect of adriamycin administered intravenously without any carrier to dogs and rabbits, in order to compare it with the action of the drug when it is administered bound to specific immunoglobulins. PMID- 6927368 TI - [Effect of methotrexate (MTX) on neoplastic (HeLa line) and normal (lymphocyte) cells]. AB - An equipment simulating the pharmacodynamics of anti-cancer drugs under time lapse microcinematography is described. It consists of an inverted microscope furnished with an incubating chamber, a motion-picture camera, an intervalometer, a gradient forming device and peristaltic pump. In this work, the equipment is used to study the effect of methotrexate (MTX) on cultures of HeLa cells and HeLa cell-sensitized lymphoblasts. MTX inhibits cell reproduction of both, HeLa cells and lymphoblasts, prolongs twice the generation time of the cancer cells, and produces a progressive cell degeneration. MTX produces also an early degeneration of lymphoblasts. All these data are studied by individual frame analysis of the films. PMID- 6927369 TI - [Immunogenicity of cancer-associated and cancer-specific antigens]. AB - The immunogenicity and anti-tumor activity of tumor-specific and tumor-associated antigens (TSA and TAA) isolated from the Ehrlich ascites cancer (EAC) cell plasma membrane is assayed, and compared with the action of several crude antigenic preparations. Control animals die 26 days after the EAC cells inoculation. Crude antigenic preparations produce a delay of EAC development, but all the animals finally die. The purified TSA and TAA are active at very small amounts, and inhibit completely and permanently the tumor development. The procedure shows a new approach to cancer specific active immunotherapy. PMID- 6927370 TI - [Circulating immune complexes in the serum of tumor patients]. AB - The conditions for the detection of circulating immune complexes (CIC) were established by combination of polyethylene glycol precipitation with a nephelometric determination on the precipitate of endogenous C1q. The CIC precipitated from the sera of patients with breast carcinoma, malignant melanoma or autoimmune diseases were dissociated in SDS-beta-mercaptoethanol buffer and no differences were observed in the electrophoretic patterns os polyacrylamide gels allowing to characterize tumour specific antigens. PMID- 6927373 TI - [Theoretical design of antineoplastic drugs]. AB - The author describes how to make the theoretical design of anti-cancer drugs by means of quantum mechanics pharmacology calculations. PMID- 6927372 TI - [Changes in the serum immunoglobulin levels in mice with methylcholanthrene induced fibrosarcoma]. AB - The serum immunoglobulin levels in mice with methylcholanthrene-induced sarcomas are studied. The results differ in the several groups of mice according to the localization of the tumor, and to the presence or absence of spleen. PMID- 6927371 TI - [Leukocyte adherence inhibition test in tumor patients]. AB - The leukocytes from cancer patients lose the capacity to adhere themselves to the tube glass surface when they are incubated with antigenic extracts of neoplasms of the same histologic type, as observed employing the leukocyte adherence inhibition (LAI) test. The authors confirm that the LAI test is organ-specific when primary tumors are employed as a source of antigens. Contrarily, the LAI test does not give a useful diagnostic information when antigens from metastases are employed. On the other hand, the practice of cell counts at 20 minutes intervals, shows that we are not dealing with a true adherence inhibition, but with a massive initial adherence of the leukocytes to the glass surface, followed by the further detachment of the cells. The phenomenon depends on cell concentration and it is not observed when less than 1000 leukocytes mm2 are used. PMID- 6927374 TI - [Transrecters. A new group of inducers of reverse transformation with possible use in the treatment of human cancer]. PMID- 6927375 TI - Neurotization or nerve transfer for brachial plexus lesions. AB - Neurotization is one of the methods available for treating avulsive lesions of the brachial plexus. It has to be inserted into a series of other procedures when all the roots are not avulsed when all of them are avulsed but represents the only chance. It can only hope to restore some simple function to replace the very complex ones which have been lost. It has limited applications but is fully justified when one is dealing with a totally paralyzed limb. Finally, it can improve the trophicity of the limb and relieve the severe pain which is present in some 40% of cases of avulsive lesions, a problem which cannot be developed here. It is necessary that the patients and the surgeons realize its limits in order to avoid disappointment. PMID- 6927376 TI - Osseous metastases in the hand. A general review of three cases. AB - Osseous metastases in the hand are rare. The authors report 3 cases, bringing the total number of reported cases up to 106. They affect mainly men; their clinical features are local swelling and pain frequently ascribed to a trauma. The diagnosis is often mistaken, many patients being initially treated for a distal felon. Distal phalanx is the main involved area, with irregular osteolysis and cortical destruction. The etiology is quite different from that of metastases to other bones: bronchopulmonary cancer is by far the most frequent with 46% of cases, followed by breast cancer (15%). Other types of cancer are much less frequently involved. The evolution is sombre; average life expectancy is 3 1/2 months. Treatment may involve, as needed, distal digital amputation on antalgic radiotherapy. PMID- 6927377 TI - Arterial vascularization of the trapezo-metacarpal joint. AB - The authors have dissected 24 hands previously injected with a mixture of micropaque gelatin and minium. The arterial supply of the trapezo-metacarpal joint is provided through an anastomotic circle connecting four networks (dorsal, volar, ulnar and radial). These four networks are all supplied by branches from the radial artery. Each network has one main artery and several other additional smaller arteries. Even when the radial artery has an abnormal direction, the same type of vascular supply for the trapezo-metacarpal joint is preserved, but its sources are different. PMID- 6927378 TI - Principles and experimentation of wrist prostheses of the universal joint type. AB - The till now wrist prosthesis have a poor rotatory stability either they are flexible or rigid; specially the spheric ones, they are unable, from their very conception, to transmit the pronation-supination; the condylar ones have an incomplete stability because of their insufficient embedding. The prono supination transmission needs a "universal joint" prosthesis, whose sellar surfaces are deeply embedded; so, it is possible to get in the same time firm stability and normal ranges of motion. The articular components, crescent roll shaped, are chained each other in perpendicularly plans and fixed in the radius and in the carpus-metacarpus. This is the mono-articular prosthesis, radio carpal, type A. With an ulna piece, articulated with the radial one by a spherical pivot, we have a bi-articular prosthesis, type B, including the lower radio-ulnar joint: so we have the true total wrist prosthesis. Experimented on cadaveric specimens, these two prostheses, inserted by dorsal approach, have physiologic ranges of motion and absolute rotatory stability. Further studies may define the best dimensions of the prosthesis according to individual variations and ancillary tools set, before beginning the clinical experimentation. PMID- 6927379 TI - [Injuries of the trapezo-metacarpal joint]. AB - The trapezo-metacarpal joint has a complex structure with specific anatomical, physiological, radiological and clinical characteristics. Several anatomical descriptions of this joint are available, and we believe one should know it well in order to understand its radiological problems. For instance a wrong projection may lead to overlook a fracture, especially in the trapezium. Several mechanisms have been suggested to explain the lesions of the base of the first metacarpal and of the trapezium. The therapeutic consequences of these considerations are not very important. Regardless of the lesion, two methods seem to yield the best results: Iselin's double pinning; oblique traction as suggested by L. Thoren. A perfect reduction is most important in both methods, as is usually the case fort any articular structure. This will reduce the risk of trapezo-metacarpal arthritis which still remains an unpredictable complication. PMID- 6927380 TI - [Covering distal amputations of the finger using homodigital neurovascular island flaps]. AB - Large skin defects of the tips of the fingers are difficult to manage. The authors have used in fourteen cases a neurovascular homodigital island flap to cover the defect. Functional and esthetic results have been very encouraging. PMID- 6927381 TI - [Simultaneous functional bilateral radiographies of the metacarpophalangeal joint of the thumb in hyper-pronation]. AB - Diagnosis of tears of the ulnar collateral ligament of the metacarpophalangeal joint of the thumb is often made by dynamic radiography. In contrary to the usual technic, the best position is forced pronation of the hand. The metacarpal and the first phalanx are horizontal on the X ray plate. The patient is encouraged to push the tip of his thumb against an object thus obtaining a forced abduction. The two hands can be held in place with a tight bandage. This yields a simultaneous and symmetrical image of the two thumbs on the same film. PMID- 6927382 TI - Early tendon transfers in the rehabilitation of median, radial, and ulnar palsies. AB - Early tendon transfers car restore a balanced simplification of motor performance and provide an essential component for re-education of sensation. Recommended transfers include the extensor indicis proprius to restore thumb opposition in low median palsy, the pronator teres to restore wrist extension in radial palsy, and the multi-tailed single flexor digitorum superficialis to restore thumb-index pinch and prevent ring-little finger clawing in low ulnar palsy. PMID- 6927385 TI - [Three cases of intrabronchial foreign bodies]. PMID- 6927383 TI - [The study of the reconstruction of tissue defects with artificial materials, especially in the chest wall, diaphragm and pericardium]. PMID- 6927384 TI - [A case of benign mediastinal teratoma operated on after eleven years' observation]. PMID- 6927386 TI - Reflections on the internal primary, secondary and tertiary structure homology of the eye lens proteins alpha-, beta- and gamma-crystallin. PMID- 6927387 TI - Eye-lens proteins: the three-dimensional structure of beta-crystallin predicted from monomeric gamma-crystallin. PMID- 6927389 TI - Hormonal secretion during sleep in man. Modification of growth hormone and prolactin secretion by interruption and selective deprivation of sleep. PMID- 6927390 TI - REM sleep, dreaming and "dream detector". PMID- 6927395 TI - Restless legs syndrome and nocturnal myoclonus. PMID- 6927396 TI - Changes in sleep dreams by frontal and parietal lobes lesions. PMID- 6927399 TI - Ultrastructure of peritoneal macrophages in osteopetrotic (ia) and normal littermate rats. PMID- 6927400 TI - An improvement of the device for rapid freezing by use of liquid propane and the application of immunocytochemistry to the resin section of rapid-frozen, substitution-fixed anterior pituitary gland. PMID- 6927401 TI - Quantitative measurements of radiation damage to hydrated specimens observed in a wet gas environment. PMID- 6927398 TI - An ultrastructural observation of mouse fertilization in vivo as revealed by 200 kV electron microscopy. PMID- 6927403 TI - Application of cryomicrotomy to the rapid-freeze, deep-etch replica method for unfixed tissues and cells. PMID- 6927404 TI - An improved method for both light and scanning electron microscopy in backscattered electron mode of identical sites in semi-thin tissue sections embedded in GMA and Quetol 523. PMID- 6927402 TI - Scanning electron microscopy on ion-etching of enamel and dentin. PMID- 6927405 TI - An improved method for both light and electron microscopy of identical sites in semi-thin tissue sections embedded in epoxy resin "Quetol 651". PMID- 6927408 TI - Virus-like particles in the taste buds of the circumvallate papilla of the rat. PMID- 6927407 TI - The continuity of endoplasmic reticulum in rat spermatids observed by scanning electron microscopy. PMID- 6927406 TI - An electron microscopic observation of rat peritoneal cells processed by rapid freezing and freeze-substitution fixation. PMID- 6927409 TI - Fixation of germinating conidia of Meria coniospora Drechsler with KMnO4. PMID- 6927410 TI - Structural diversity of microtubules in the supporting cells of the sensory epithelium of guinea pig organ of Corti. PMID- 6927412 TI - The thirty-eighth annual meeting of the Japanese Society of Electron Microscopy. Tokyo, May 26-28, 1982. PMID- 6927411 TI - Heating water treatment for cryo-SEM of helminths and medical insects. PMID- 6927413 TI - [Childhood periodic syndromes and their long-term development]. AB - The long term development of periodic syndromes among children is little known. Our research has revealed that about one third of periodic headaches, two thirds of cyclic vomiting and half the cases of recurring abdominal pain disappear either before puberty or during adolescence. Other Authors have shown that this also happens in most cases of early-onset vertigo. The remaining headache cases develop into migraines in adults. When there is persistent cyclic vomiting, the collateral neurologic phenomena (headaches, vertigo, pallor, hypotonia, drowsiness) become more intense. This also happens in some cases of abdominal pain and paroxysmal vertigo which start in late childhood. Other sufferers from acute abdominal pain develop ulcers, gastroduodenitis and colitis as adults. Altogether, some infantile periodic syndromes (in particular the multi symptomatic ones) have a common outcome, i.e. develop into more or less typical migraine syndromes. In these cases one can presume a common pathogenetic mechanism. In those cases where the outcome is favorable the pathogenesis may be different. These cases may often be spotted in early childhood on account of the monosymptomatic nature of the complaint or the absence of collateral neurologic symptoms as well as of the infrequency of critical episodes. PMID- 6927414 TI - [Radioimmunologic analysis of calcitonin and parathyroid hormone in the study of calcium homeostasis in the newborn infant during the first days of life]. AB - Measurements of serum calcium on the first, third and sixth day of life and serum Parathyroid hormone (PTH) and Calcitonin (CT) by radioimmunoassay on the first and third day of life have been effected on a group of 31 infants born after 29 42 weeks of gestation and weighing at birthday 1300-3510 g. The mean serum iCT levels on the first day of life (996 +/- 95 pg/ml) were significantly higher than on the third day of life (533 +/- 79 pg/ml; p less than 0,001) and both were upper normal range of method (200 pg/ml). Mean serum iCT values were found negatively correlated both with birthweight (p less than 0,025) and with gestational age (on 1st day p less than 0,02; on 3rd day p less than 0,001) in AGA newborns. No correlation was found between iCT values and serum Calcium values. The mean serum iPTH levels on the first and third day of life were in the normal range (on 1st day 416 +/- 61 pg/ml; on 3 rd day 640 +/- 114 pg/ml) and not correlated neither with serum Calcium and serum iCT levels, nor with birthweight and gestational age of the newborns. It is excluded that any transient hypoparathyroidism can cause early neonatal hypocalcemia and it is confirmed the presence of high levels of serum Calcitonin in term and premature infants. PMID- 6927415 TI - [Closure of Botallo's ductus arteriosus with indomethacin. Considerations on 4 cases]. AB - Persistence of Patent Ductus Arteriosus (PDA) frequently occurs in preterm infants. In a remarkable number of cases, PDA may undergo spontaneous closure. In other cases, especially in patients with respiratory problems, a ductal left-to right shunt may compromise the cardiac-respiratory function. Until a few years ago, surgery was the only possible therapy. Recently, pharmacological closure of the duct by means of Indomethacin, a powerful inhibitor of prostaglandin synthesis, was successfully carried out. The medical treatment, however, appears to be less effective if it is carried out on patients older than 2 weeks. It has also been reported that in patient with a very low birthweight and with lack of muscular tissue in the duct wall, closure of the duct may be transient. It is the purpose of this communication to report observations made on 4 preterm infants of 24-33 weeks gestational age, and with a weight range of 660 to 2.280 g. They received Indomethacin via naso-gastric tube, in a single dose of 0,3 mg/Kg, within 8 days of age. Successful closure of the PDA was obtained in all cases. The pharmacological treatment resulted also in reductions in ventilatory support requirements, reduced respiratory component of acidosis, reduced pCO2, increased pO2. A second administrations of Indo was necessary only in one case, and it was followed by permanent closure of the duct. Collateral effects, such as reduced diuresis and reduced number of platelets, were transient. Indo therapy was successful regardless of very low birthweight: in three cases, birthweight was under 1.000 g.(ABSTRACT TRUNCATED AT 250 WORDS) PMID- 6927416 TI - [Bronchiolitis: new pathogenetic aspects and personal cases]. AB - The etiological, epidemiological and pathogenetical features of bronchiolitis and some clinical and biochemical data concerning seventy nine cases were discussed. It has been underlined the possible pathogenetical role of immunoallergic mechanism (immunoreactions type II, III, IV and VI), and of alterations of humoral immunocompetence (rise of IgM and deficit of IgA). Moreover it has been pointed out that hereditary, socioeconomical and environmental factors could play an important role in determining the seriousness of the clinical picture. The relationship between bronchiolitis and the respiratory diseases of the following years have been examinated. PMID- 6927417 TI - [Results of a screening project for congenital hypothyroidism in 4 years of experience]. AB - A screening program for congenital hypothyroidism has been starting in Siena since November, 1977 with the Guthrie's test for PKU. According to the recommendations of the Committee of the European Thyroid Association the program were performed on capillary blood samples collected between the fourth and sixth days after birth on an adsorbent paper. The screening began with the measurement of T4 RIA (up to May, 1980), and T4 and TSH RIA (from may, 1980, to december, 1981). At december, 1981, 23.693 newborns have been screened. The recall rate was 2,5% up to may, 1980, and 0,11% from may, 1980 to december, 1981. Ten newborns with congenital hypothyroidism have been detected; the incidence is one in 2.400 live births. There were no cases of transient hypothyroidism and no cases of TBG deficiency. All patients are treated before the age of one month. The diagnosis is confirmed in seven cases at one year of life after stopterapy for one month. Our program confirm the high incidence of congenital hypothyroidism. Clinical control, based on physical and psychomotor development testing in seven patients treated confirmed that all infants are normal. PMID- 6927418 TI - [Hydrocele and inguinal hernia after ventriculo-peritoneal shunt in childhood]. AB - 135 non tumoral hydrocephalic children have been operated on trough a V-P shunt in the period January 1975-June 1981. Of them, 10 (7.4%) presented an inguinal hernia or hydrocele in the postoperative period. Such complications required in 9 cases a specific surgical treatment, which was not followed by recurrence in any case; in one child the hydrocele subsided spontaneously. No relation was found with the type of shunt device inserted and the side of the operation. PMID- 6927419 TI - [An alternative method of percutaneous introduction of central venous catheters: experience in 20 cases in pediatric surgery]. AB - An alternative method of percutaneous introduction of a central venous catheter through a periferal antecubital vein, in neonates and infants, is presented. The AA. prefers this method beeing safer, less traumatic and easier to performe than the other commonly used techniques. PMID- 6927420 TI - [Trends in the therapy of cleft lip]. AB - The treatment of cleft lips is a complex problem that need an interdisciplinary approach, involving the effort of many specialists. The constant improvement of plastic surgery has today reached highly qualified techniques that permit satisfactory results in most cases. We report our long experience, including more than 500 cases of cleft lips, stressing the right sequence and the basilar principles of their correction. PMID- 6927422 TI - [Hypothyroxinemia in the low birth-weight infant in the screening of congenital hypothyroidism]. AB - Inside a pilot screening program for Congenital Hypothyroidism, T4 and TSH have been tested in sick and healty preteam and fullterm low birth weight (LBW) newborns during the first two months of life, 36 newborns affected by respiratory distress syndrome and 15 by sepsis have been included in the study. Blood samples were collected by heel puncture on 3rd, 10th, 20th, 40th and, in some cases, up to 60th day of life, and adsorbed on filter paper. Our findings show that hypothyroxinaemia in LBW newborns is strictly related to gestational age. In fact, among preterm infants with GA less than or equal to 33 weeks, 25 subjects (69,44%) showed T4 levels less than or equal to 6 micrograms/dl and 5 infants (13,88%) had T4 concentrations less than or equal to 2 micrograms/dl. The incidence of subjects with T4 values less than or equal to 6 micrograms/dl falls to 42,18% in the group of infants with GA = 34-36 weeks and to 17,27% in the group of fullterm LBW infants. None of these newborns showed thyroxine levels less than or equal to 2 micrograms/dl. All the examined infants showed normal TSH levels. The low T4 values may appear soon after birth or later (3rd-20th day of life) and sometimes persist up to 40th or 60th day, despite of always normal TSH levels. The mean of low T4 values at each sampling time is strictly and directly related to gestational age. (ABSTRACT TRUNCATED AT 250 WORDS) PMID- 6927421 TI - [Incidence of osteomyelitis and septic arthritis in a neonatal pathology unit]. AB - During a five years period 8 newborns on 2035 admissions developed septic arthritis representing a very low incidence of 4%. Umbilical catheters were used in 3 patients. Staphylococcus aureus was the most frequent etiologic agent and in 6/8 cases blood cultures were positive for the same pathogen agent. Because of the paucity of clinical signs in the first period in the sick neonate, detection of the disorder by the radiologist assumes great importance in the neonatal intensive care unit, as early recognition and therapy may prevent residual deformity. PMID- 6927423 TI - [Efficacy of dietetic treatment in a case of galactosemia diagnosed late]. AB - The authors describe a six months old girl affected by galactosemia, due to Galacto-1-phosphate Uridyl Transferase deficiency. The patient presented with hepatosplenomegaly and failure to thrive, without neurological impairment or cataracts. In this case removal of galactose from diet, although lately performed, resulted in normal growth and development. The authors emphasize the importance of ruling out galactosemia, even if clinical picture is unusual. PMID- 6927424 TI - [Peritonitis caused by the rupture of an amebic abscess of the liver in childhood]. AB - The peritonitis from the rupture of the amebic liver's abscess is a not rare complication of the hepatic amebiasis in the children, with a poor prognosis. The usual treatment is loaded with a high morbility and mortality. The AA show a therapeutic screen based on saucerization with debridment and on the installation of a disposal of peritoneal washing. The above mentioned treatment is looking at the recovery of the organ and consequently at the direct removal of the "primum movens" of the septic shock and generalized peritonitis. PMID- 6927425 TI - [A case of ectopic vas deferens opening into the bladder]. AB - A case of epididymitis in a two years old boy owing to an ectopic vas deferens opening into the bladder is reported. Only a very few similar cases have been recorded in the world literature. PMID- 6927427 TI - Twenty-third annual meeting of the American Society of Hematology. San Antonio, Texas, December 5-8, 1981. Abstracts. PMID- 6927426 TI - [Buschke's scleredema and carditis: a clinical case]. AB - An 11-year old girl who presented non-pitting edema of the face and neck, shoulder pain and a gallop rhythm about 10 days after a febrile episode with sore throat is described. The mask-like facial appearance and limited movement of the neck led to suspect scleredema which may be accompanied by carditis. Skin and muscle biopsy findings confirmed the diagnosis. Cardiac involvement included a gallop rhythm persisting for 6 months, ECG changes consisting in transitory T wave inversion in leads II and V2 - V4, a transitory pericardial function rub and hepatomegaly due to right-sided failure which responded to digitalization. In this case the presence of a gallop rhythm and elevated ASLO titer led to an initial diagnosis of acute rheumatic fever; dermatomysitis and sclerodermia are also to be considered in the differential diagnosis of scleredema of Buschke. In our patient the edema resolved completely within 12 months, the gallop rhythm within 6 months and the ECG became normal after 8 months. PMID- 6927428 TI - Twenty-fourth annual meeting of the American Society of Hematology. Washington, D.C., December 4-7, 1982. Abstracts. PMID- 6927429 TI - [Diagnosis of intrapericardial abnormalities by bidimensional echocardiography]. PMID- 6927430 TI - [Electrocardiographic and hemodynamic response to exercise in supine position in a population of normal subjects]. PMID- 6927431 TI - [Effect of the anti-hypertensive therapy with atenolol on the dimensions and function of the left ventricle]. PMID- 6927432 TI - Induced concealed atrial flutter. PMID- 6927433 TI - Heart rate and rhythm during underwater swimming. PMID- 6927434 TI - [Propafenone: a new anti-arrhythmic agent for the treatment of ventricular ectopic beats]. PMID- 6927435 TI - [Electrophysiologic effects of prenalterol On sinus function in coronary disease patients]. PMID- 6927438 TI - [Fourier analysis of left ventricular dyskinesia in myocardia infarct]. PMID- 6927436 TI - [Lupus pericarditis: immunopathogenetic aspects and clinico-diagnostic features]. PMID- 6927437 TI - [Valsalva's maneuver in the evaluation of the baroceptor sensitivity in borderline hypertensives: comparative study of other methods]. PMID- 6927441 TI - [Effect of isosorbide dinitrate on platelet aggregation and production of thromboxane B2]. PMID- 6927442 TI - A guide for instrument development and validation. AB - As occupational therapists become increasingly concerned with accountability, the paucity of adequate instrumentation available for documenting therapeutic effectiveness surfaces as a major problem. Therapists will need to construct new or refine existing instruments to satisfy the requirements of third-party payment. The purpose of this paper is to illustrate how a new instrument is planned, developed, and validated. A sequential step-by-step process is illustrated with a flowchart and applied in the hypothetical construction of an attitude scale to assess school administrators' valuing of the role of occupational therapists in the schools. This example is provided to show how general psychometric principles are applied within an occupational therapy context. PMID- 6927440 TI - [Ischemic changes in the primary syndrome of mitral valve prolapse. Apropos of a case regressing after prosthetic valve substitution]. PMID- 6927443 TI - [Experimental and clinical pharmacokinetics of amrinone]. PMID- 6927444 TI - [Double-outlet right ventricle. Problems in echocardiographic diagnosis]. PMID- 6927439 TI - [Surgical treatment of patients with trivalvular disease: results and evaluation of perioperative risks]. PMID- 6927445 TI - [Relationship between the afterload electrocardiographic picture and dynamics of the left ventricle in hypertensive cardiopathy]. PMID- 6927446 TI - [Metabolic and functional correlations during post-ischemic reperfusion]. PMID- 6927447 TI - [Mitral prolapse: critical review of 87 cases studied by the T-motion technic]. PMID- 6927448 TI - [Effects of bed rest on cardiocirculatory function]. PMID- 6927450 TI - [Ejection fraction and average rate of circumferential contraction of the left ventricle evaluated by the apex cardiogram. Correlation with echocardiographic and angiographic measurements]. PMID- 6927449 TI - [Blood gas analysis findings at rest and after exertion in adult patients with beta-thalassemia intermedia: preliminary observations]. PMID- 6927451 TI - [The combined use of dynamic electrocardiography and exercise ECG in the study of myocardial ischemia]. PMID- 6927453 TI - [Predictive capacity of a bloodless method in subjects with atypical angina symptomatology]. PMID- 6927452 TI - [Analysis of normal behavior of electrocardiographic parameters found during exercise in a supine position]. PMID- 6927454 TI - [Vagal hypertonicity in congenital AV block. Apropos of a case]. PMID- 6927455 TI - [Efficacy of nifedipine in combination with propranolol in the therapy of primary arterial hypertension of moderate degree]. PMID- 6927456 TI - [Prolapse of the mitral valve associated with an interatrial defect]. PMID- 6927457 TI - [Effects of flurbiprofen on platelet function in patients with ischemic cardiomyopathy]. PMID- 6927458 TI - [Evaluation of the efficacy of verapamil in slow-release preparations in the treatment of stable exertion angina]. PMID- 6927459 TI - [Possibility of prediction of sudden cardiac arrest in arterial hypertension: septal hypertrophy]. PMID- 6927460 TI - [Phase 4 alternating left bundle branch block. Considerations on a case report]. PMID- 6927462 TI - [Variations of QRS and echocardiographic dimensions of the left ventricle in relation to muscular exercise in sitting position by normal individuals]. PMID- 6927461 TI - [Validity of Bayesian strategy in the noninvasive clinical diagnosis of atherosclerotic coronary disease]. PMID- 6927463 TI - [Intraoperative hemodynamic findings in high-risk patients with mitral valve disease]. PMID- 6927464 TI - [Incidence of sudden death in the follow-up of 409 cases of rehabilitated infarction]. PMID- 6927466 TI - [Hemodynamic evaluation of chronic aortic insufficiency using isotonic exercise (its usefulness in the determination of incipient ventricular dysfunction)]. PMID- 6927470 TI - [Methods, problems and perspectives of endomyocardial biopsy]. PMID- 6927467 TI - [Echocardiographic diagnosis of ventricular dyskinesia in patients with coronary disease and normal function at rest by using limited increased pressure in ischemia caused isometric exercise]. PMID- 6927471 TI - [2-dimensional echocardiography in the execution of myocardial biopsy]. PMID- 6927469 TI - [Quantification of the variable threshold of ischemia in secondary and primary angina using studies of myocardial perfusion with thallium 201 in serial exercise tests]. PMID- 6927465 TI - [Incidence of arrhythmia in post-infarction period]. PMID- 6927468 TI - [Study of the global and segmental biventricular function in patients with lesions of the right coronary artery using exercise isotopic ventriculography]. PMID- 6927472 TI - [Hemodynamic-angiographical parameters and bioptic histomorphological findings in patients with suspected idiopathic dilated cardiomyopathy]. PMID- 6927474 TI - [Antagonism of sulpiride to the action of ibopamine at the level of peripheral circulation]. PMID- 6927473 TI - [Clinical, electrophysiological and histological findings in a case of sustained idiopathic ventricular tachycardia]. PMID- 6927475 TI - [Effects of ibopamine on the peripheral circulation of normal subjects after protracted administration]. PMID- 6927478 TI - [Anti-hypertensive efficacy and metabolic effects of fenquizone after a year's treatment]. PMID- 6927479 TI - [Primary and secondary hypertension: value and limits of a simple diagnostic work up in the etiological definition of hypertension in a general population]. PMID- 6927477 TI - [Strain gauge plethysmography in the evaluation of the effect of acute administration of ibopamine on the peripheral circulation of normal subjects]. PMID- 6927482 TI - [Echocardiography evaluation of cardiocirculatory response to the "cold pressor test" in healthy subjects]. PMID- 6927480 TI - [Renal reflexes in the rat determined by natural stimulation of renal chemoreceptors]. PMID- 6927481 TI - [In vitro effect of verapamil on the function of isolated mitochondria of the rabbit heart perfused under conditions of aerobiosis, ischemia and reperfusion]. PMID- 6927484 TI - [Hypersensitivity of the carotid sinus. Follow-up of 44 symptomatic patients]. PMID- 6927485 TI - [Efficacy of pharmacological prevention after the first attack of ventricular tachycardia]. PMID- 6927483 TI - [Echocardiographic evaluation of the effects of nadolol on left ventricular performance in hypertensive subjects]. PMID- 6927476 TI - [Possible myocardial damage caused by electric countershock: analysis of CPK MB isoenzyme variations]. PMID- 6927486 TI - [Electric memory of the heart. Residual changes in the T wave after regression of abnormalities of ventricular activation: an attempt at unitary interpretation]. PMID- 6927487 TI - [Continuous electrocardiogram in ischemic heart disease]. PMID- 6927488 TI - [Correlation of infarct area and function of the left ventricle evaluated at a later time by angiocardioscintigraphy]. PMID- 6927489 TI - [Vectorcardiographic changes during exertion in normal subjects]. PMID- 6927490 TI - [Anamnestic study of thoracic pain: comparison of angina and gastroesophageal reflux]. PMID- 6927491 TI - [Course and prognosis of ventricular tachycardia associated with cardiopathy]. PMID- 6927492 TI - [Diagnostic and prognostic value of radioimmunologic determination of myoglobin in myocardial infarction]. PMID- 6927493 TI - Criteria for two-dimensional echocardiographic diagnosis of atrioventricular and ventriculo-arterial discordance, and associated anomalies. PMID- 6927494 TI - [Cardiovascular response to mental stress, dynamic and isometric exercise in a group of hypertensive patients treated with prizidilol (SK&F 92657)]. PMID- 6927497 TI - [The role of myocardial scintigraphy in the identification of lesions of the anterior descending branch or the three coronary veins]. PMID- 6927495 TI - [Ostial stenosis of the left heart. Diagnostic difficulties and risk of cardiographic examination. Description of 2 cases]. PMID- 6927499 TI - [Evaluation of the dependability of an arrhythmia monitoring system]. PMID- 6927498 TI - [Mid-term results in atrial guided and bifocal permanent atrial stimulation]. PMID- 6927496 TI - [Reintervention in patients with a Hancock prosthesis in mitral and aortic position]. PMID- 6927500 TI - [Evaluation of coronary risk factors in a 30-year-old population from the province of Varese]. PMID- 6927501 TI - [Therapeutic criteria in the use of nifedipine in patients with chronic aortic insufficiency]. PMID- 6927502 TI - [Organization of the cardiology in the territory]. PMID- 6927506 TI - [Harmonic analysis of atrial depolarization in high-resolution electrocardiography]. PMID- 6927503 TI - [Valve prostheses in children and adolescents]. PMID- 6927504 TI - [Episodes of asymptomatic myocardial ischemia in subjects with vascular risk factors. Interpretations on the absence of pain]. PMID- 6927505 TI - [Secondary amyloidosis of the heart. Diagnostic validity of two- dimensional echocardiography. A case report]. PMID- 6927507 TI - [Left ventricular function in the natural history of interatrial communication of the ostium secundum type]. PMID- 6927508 TI - Separation of platelet-rich plasma by modified centrifugal elutriation. AB - The Beckman centrifugal elutriation (CE) system is modified for the separation of platelet-rich plasma (PRP) from human and rabbit blood. The Beckman separation chamber is found inadequate for this purpose, and a new chamber of conical shape has been developed. Optimal flow rate for separating PRP from whole blood with the new chamber of 11.3 ml capacity is 3.5 ml/min while centrifuging at 2500 rpm or 700 g. Collection process takes about 4 minutes. This new process is based on the principle of centrifugal counterflow displacement and filtration, and is different from the CE process which is based on counterflow centrifugation and differential elution. About 90% of total platelets are recovered with this new process. The collected samples are free of leucocytes and contained only a few erythrocytes. Platelets collected by either differential centrifugation (DC) or new procedures are found to be similar in morphological characteristics, both being discoidal. Other characteristics such as aggregation response induced by ADP or epinephrine, serotonin-14C secretion, and survival of autologous platelets in rabbits are also found to be similar. However, ATP release induced by ADP is consistently higher from platelets prepared by our procedure than from those prepared by the DC procedure. PMID- 6927509 TI - Plasmapheresis in lupus nephritis with nephrotic syndrome: a long-term followup. AB - Lupus nephritis with nephrotic syndrome is one of the most serious complications of systemic lupus erythematosus. Six female patients with systemic lupus and nephrotic syndrome, refractory to immunosuppressive drug therapy, received 15-20 exchange plasmaphereses. One patient, treated concurrently with high-dose steroids, showed temporary improvement, and five patients, treated concurrently with steroids and either cyclophosphamide or azathioprine, had long-term remissions. Plasmapheresis is a promising therapeutic modality in cases of refractory lupus nephritis with nephrotic syndrome. PMID- 6927511 TI - National Center for Health Care Technology assessment of therapeutic apheresis for rheumatoid arthritis, 1981. AB - The National Center for Health Care Technology coordinated the Public Health Service's assessment of therapeutic apheresis for rheumatoid arthritis in response to the Health Care Financing Administration's request for advice regarding Medicare coverage of this rapidly emerging technology. The information considered included reports available in the medical literature (as of early 1981), advice from the National Institutes of Health and Food and Drug Administration, advice from the appropriate medical societies, as well as information submitted by interested parties in response to a notice published in the Federal Register announcing the assessment. Synthesis of this information provided the basis for concluding that therapeutic apheresis for rheumatoid arthritis was considered experimental with the possible exception of treatment for life-threatening complications such as vasculitis, cryoglobulinemia, or hyperviscosity syndrome. PMID- 6927512 TI - A technique for easy vascular access in patients undergoing plasmapheresis. AB - Gaining vascular access in some patients undergoing plasmapheresis procedure may prove to be difficult. Twenty-four percent of our patients had either a poor vascular access or poor blood flow. This report describes a technique for obtaining good vascular access in otherwise difficult patients, which we believe to be easy, safe, time saving and cost effective. PMID- 6927510 TI - Childhood chronic relapsing polyneuropathy: dramatic improvement following plasmapheresis. AB - We present clinical data on two boys with chronic relapsing polyneuropathy. Their recurrent episodes of weakness had produced marked disability which was unresponsive to continuous prednisone therapy. Plasmapheresis produced dramatic improvement in muscle strength and functional ability. The remissions induced have been sustained despite withdrawal of steroid therapy. PMID- 6927514 TI - Epidemiologic evaluation of large-scale perinatal programs. PMID- 6927513 TI - Treatment of thrombotic thrombocytopenic purpura with plasma exchange, antiplatelet agents, corticosteroid, and plasma infusion: Mayo Clinic experience. AB - Ten patients with thrombocytopenia (TTP) were treated recently in our institution with plasma exchange (PE), steroids, and antiplatelet drugs. Additionally, fresh frozen plasma (FFP) was administered to nine patients, with folic acid given to eight patients. After 13 to 25 months of follow-up, we found that four patients achieved and remained in remission after initial treatment. Three patients had four relapses, which developed while they were taking antiplatelet therapy, and which were treated successfully with FFP alone, or with PE in addition to FFP. Four patients suffered major neurological or renal damage during their presentation or initial treatment. One of these patients died during his initial hospitalization. Another patient died 7 months after initial treatment. After analyzing this experience, we have concluded that antiplatelet drugs or corticosteroid should be used as the sole initial treatment most cautiously. The relative importance of the exchange process, per se, versus plasma infusion cannot be inferred from our observations, but plasma exchange with FFP appears to have had a real impact on recovery. PMID- 6927515 TI - Preferences for health states: a review of measurement methods. AB - The preferences of patients and the public for program outcomes are an important component of program evaluation. This paper reviews methods of measuring such preferences. Topics discussed include the description of the relevant health states, the selection of appropriate subjects, the types of preference scales available and the various preference measurement methods which can be used. The three most common preference measurement techniques--rating scales, standard gamble and time trade-off--are described in detail. The application to both temporary and chronic states is presented, including the case of chronic states considered worse than death. Findings regarding the accuracy of the techniques are summarized. PMID- 6927516 TI - Should we measure personal valuations of perinatal outcomes? PMID- 6927517 TI - [Pleural permeability to antibiotics and anticancer drugs]. PMID- 6927518 TI - [Functional changes in the pulmonary arteries of pulmonary hypertensive rats]. PMID- 6927519 TI - [Studies on the defense mechanisms of the respiratory system. III. Effect of inhaling cigarette smoke on the levels of immunoglobulins, lysozyme and antitrypsin in bronchial lavage fluids]. PMID- 6927520 TI - Chronic effects of fire casualty on pulmonary function. PMID- 6927521 TI - [Six cases of surgically treated bronchial cyst]. PMID- 6927522 TI - Neuropeptides in the brain. 9th International Symposium of the Fulton Society. PMID- 6927523 TI - Ventilatory mechanics. Abstracts. PMID- 6927524 TI - Hypoxia. Abstracts. PMID- 6927527 TI - [Changes in the spirography of paraplegics related to different postures in the air and water]. AB - Respiratory insufficiencies in subjects with spinal cord injury were studied in five situations: in the air (sitting, dorsal supine position, declivous--15 degrees), and immersed in water up to the neck (sitting, dorsal supine position). Results were compared to those for a group of normal subjects. Total lung capacity (TLC), residual volume (RV), functional residual capacity (FRC), vital capacity (VC), forced expiratory volume per second (FEV1) and peak expiratory flow (PEF) were measured and their ratios with theoretical values of each subject were calculated. In handicapped subjects, FEV1 is less significantly diminished than VC and PEF. TLC does not vary, FRC is higher only sitting in the air, RV is more increased. Between situations, FEV1 never varies. In normal subjects, RV does not vary but, sitting in the air, TLC, VC, FRC and PEF increase. In handicapped subjects sitting in the air, VC decreases, RV and FRC increase, TLC and PEF do not vary. In normal and handicapped subjects, the other situations are comparable all together. PMID- 6927525 TI - [Forced expiration index, signal and noise]. AB - Although forced expiration measurements are extensively used, there is no general agreement concerning the best way to quantify the data. In this context, it may be of interest to examine indices from the point of view of their signal/noise ratio. The signal depends upon the actual sensitivity of the index to the kind of abnormality which is to be detected. In general, the relationship between signal and degree of abnormality is strongly non-linear, so that sensitivity is not a constant. The noise depends upon the kind of investigation which is made. When a subject is compared to himself (bronchomotor challenge, follow-up studies, etc.), it is mainly due to intraindividual variability. FEV1 is an example of index with a low sensitivity to peripheral airway abnormality, but a high reproducibility, so that its signal/noise ratio for paired measurements is comparatively good. When two groups are to be compared, the relevant noise is interindividual variability. Coefficient of variation of transit times and slope ratios are quite effective in detecting abnormalities in young smokers, probably because their sensitivity to mild peripheral airway disease is large compared to their interindividual variability. It follows that, according to the type of study, as well as to the nature and extent of abnormality, many indices may qualify as being the best. PMID- 6927526 TI - Effect of alpha-methyldopa on lung microembolism in the rat. AB - The effect of chronic pretreatment with alpha-methyldopa on acute pulmonary hypertension induced by lung microembolization with Sephadex particles in the rat was studied. Alpha-methyldopa was administered twice a day for 10 days by oesophageal gavage (20 mg X kg-1 of body weight) prior to embolization. Rats were anaesthetized with urethane. A catheter was positioned in closed chest rats in the pulmonary artery and 50 microliter of Sephadex suspension in saline were injected. The control group was not pretreated with alpha-methyldopa. In a subgroup of control and pretreated rats, the cardiac output was measured by the dye dilution technique before and after lung microembolization. Rats pretreated with alpha-methyldopa had less pulmonary hypertension, higher cardiac output and more severe arterial hypoxaemia 15 min after lung microembolization than untreated animals. There was no difference in platelet counts prior and after embolization. We suggest that pulmonary hypertension after lung microembolization in the rat includes a vasoconstrictor component which can be suppressed by alpha methyldopa, and that severe arterial hypoxaemia in pretreated rats is probably the result of a decrease of the ventilation/perfusion ratio in unobstructed areas, which in untreated rats may be prevented by active vasoconstriction. PMID- 6927528 TI - Flow-volume curves in children in health and disease. AB - Pulmonary function studies were done in 136 children (5.5-17 yr old) of whom 39 had allergic type asthma, 26 chronic bronchorrhea, and 13 mucoviscidosis; the remaining 58 subjects were healthy. The children having respiratory problems were studied when they were clinically free from wheezing and pulmonary infection. Measurements of forced expiration were made with a pneumotachograph; the data were stored on a magnetic tape and analysed with a Hewlett-Packard programmed computer. Standards for the different ventilatory parameters were established for the healthy children. A step by step discriminant linear analysis of the data and application of the Kolmogorov-Smirnov test demonstrated that V25, V50 and MMEF measurements were the best discriminating parameters of pulmonary function abnormalities in the respiratory problem children. PMID- 6927529 TI - [Flow-volume curves in healthy children and adolescents 10-19 years of age. Reference values and lower limits of the normal]. AB - In 477 healthy children and adolescents (247 boys and 230 girls, aged 10 to 19 years), we measured the vital capacity (VC), the forced expiratory volume in one second (FEV1), the flow between 25 and 75% of expired forced vital capacity (FEF25-75) and the forced expiratory flows when 75, 50 and 25% of forced vital capacity remain to be expired (FEF75, FEF50, FEF25), in order to determine reference values and lower limits of the normal. Regression functions were calculated for girls and boys separately. The best correlations for pulmonary volumes and flows were obtained by taking into account simultaneously height and age in girls, height, age and weight in boys. Power function is the model of regression that fits our data the best. The regression functions determined, as well as the lower limits of the normal and the residual standard deviations, are given by sex for each of the variables measured. These results are discussed and compared with those in literature. They concern clinicians (identification of "abnormal" subjects) and epidemiologists (prevalence of ventilatory troubles, comparison of different populations), and can be used in adolescents of the same age groups. PMID- 6927532 TI - Lung cell: structure and function. PMID- 6927533 TI - Neurological aspects of breathing. PMID- 6927530 TI - A method for measuring tidal volume and lung compliance in intubated neonates in the presence of endotracheal tube leakage. AB - Leakage around the uncuffed endotracheal tube is a major cause of error in the measurement of tidal volume and compliance in intubated neonates. A correction for the leakage can be made if the intratracheal pressure is measured during inflation provided the compliance is linear and the inflation flow is held constant. A two parameter function is given that describes the pressure-time relationship under the above mentioned conditions. The validity of the function has been tested using a model of the system tube-trachea-lung. In practice, the calculation is done from data obtained by graphical analysis of the pressure-time curve. PMID- 6927531 TI - The accuracy of the Hewlett-Packard 47201A ear oximeter below 50% saturation. AB - The Hewlett-Packard 47201A ear oximeter has been shown to measure arterial oxygen saturation (SaO2) above 50% SaO2 with an accuracy of +/- 5%. Below 50% SaO2, the oximeter underestimates arterial saturation in a predictable way, thus allowing a correction factor to be used: true SaO2 = (oximeter reading + 50)/2. PMID- 6927534 TI - Pulmonary gas exchange. Abstracts. PMID- 6927535 TI - [Respiratory insufficiency and pharmacology of theophylline]. PMID- 6927537 TI - Defining "disease" in epidemiologic studies of pulmonary function: percent of predicted or difference from predicted? AB - Epidemiologic studies often seek to determine the presence and magnitude of association between a trait and a disease, and spirometry test results are often used to define "disease". We evaluated two methods of comparing observed to predicted FEV1. The percent of predicted method is the ratio of a subject's observed to predicted result, and the residual method is the difference between the predicted and the observed result. FEV1 data from 541 men were used for computer simulated sampling for epidemiologic study of groups with different age structures. The residual method was superior because it produced more consistent measures of association, was less likely to produce an apparent association when one did not exist, and is more consistent with the statistical basis of the commonly employed prediction equations. PMID- 6927538 TI - Quantification of dyspnea confirmed by voice pitch analysis. AB - Previous efforts to quantitate dyspnea are reviewed. In this study, the voice was recorded at each level of exercise on 44 healthy male subjects exercised to maximum oxygen consumption (MVO2) by incremental treadmill testing. The fundamental frequency (FO) was compared to the physical changes noted during exercise associated with dyspnea at each level of oxygen uptake (VO2) and minute ventilation (VE). FO increased linearly with VO2 and VE. FO at MVO2 was about 1.66 times FO at rest; the slope of the increase was an individual characteristic. The sum of the graded signs of dyspnea codes (dyspnea sum index, DSI) also agreed with the measured voice changes, VO2, VE and the subjective assessment of dyspnea by the subject. Equations for predicting MVO2 from submaximal exercise are given which tested favorably against the actual MVO2. Because resting FO was most affected by anxiety, the equation predicting MVO2 from FO was not as reliable as from DSI. FO is a function of elastic properties of the vocal folds, which change in response to increased VE by permitting air to pass through "air shunts" of the arytenoid aperture. This creates a falsetto characteristic to the voice and is perceived as a stress quality. FO is a measurement reflecting many changes in the larynx with stress of exercise and perceived dyspnea. The laryngeal changes during exercise are reviewed, and the basis for the correlation between qualities of the voice and quantities such as FO are suggested. PMID- 6927536 TI - Theophylline pharmacokinetics in patients with mild or severe airway obstruction. AB - A standard loading dose of aminophylline, followed by constant rate infusion for 3 h was used to study theophylline pharmacokinetics in 36 patients (age range 27 73 years) admitted to hospital during an exacerbation of chronic airway obstruction. The severity of the disease was assessed by peak expiratory flow rate and blood gas analysis. It was assumed that the severity of the disease and the patients' age, sex and smoking habits were relevant in predicting individual kinetics and hence in establishing individual theophylline dosage. Multiple regression analysis of the results failed to confirm this hypothesis and showed no significant relationship between the severity of the disease and pharmacokinetics even when other biological variables were taken into account. The results confirm the importance of careful monitoring of blood levels of theophylline since they cannot be predicted from functional indices of the severity of obstructive lung disease. PMID- 6927540 TI - Regional hypoventilation and bronchoconstriction during pulmonary air embolism. AB - The hypothesis that experimental pulmonary air embolism would lead to bronchoconstriction in the upper lungs and a shift in ventilation toward the lower lung regions was tested in anaesthetized and paralyzed dogs. During constant rate air infusion (0.15 ml X kg-1 X min-1), regional distribution indices were obtained using radioactive xenon boli injected at the mouth at residual volume. The results show that there was a shift of inspired xenon toward the dependent lungs after 30 min of air infusion and that this shift was accompanied by a rise in pulmonary artery pressure, a slight decrease in vital capacity, a significant increase in closing volume and an increase in airway resistance. Inspiring 5% CO2 after the shift did not reverse the distribution of xenon boli. Intravenous injection of isoproterenol after the changes had occurred, on the other hand, invariably returned the distribution toward control values. These findings indicate that hypoventilation and bronchoconstriction occurred in the non-dependent lungs during pulmonary air embolism. PMID- 6927539 TI - Occlusion pressure and breathing pattern in children with chronic obstructive pulmonary disease. AB - The control of breathing at rest was studied in 30 children (3 to 17 years old) with chronic obstructive pulmonary disease (COPD). Five of them were tested several times during the follow-up of the COPD. Breathing pattern was evaluated and mouth occlusion pressure (PO.1) was measured. Results in COPD children were compared to previously reported values in healthy controls. PO.1 was significantly increased. In 11 children breathing O2, PO.1 decreased but remained at higher levels than predicted. However, the decrease in PO.1 in COPD was not significantly greater than in healthy children. These results may be explained by the relative mild hypoxemia in those children. The increase in PO.1 was significantly correlated with the increase in lung resistance (p less than 0.02) and with the decrease in dynamic lung compliance (p less than 0.01). Most of the COPD children were normocapnic. However, modifications in the breathing pattern were observed. The inspiratory time (TI) was significantly shortened, the expiratory time was prolonged and the TI over the total duration of the respiratory cycle was lowered. The respiratory frequency was unchanged. The tidal volume, normalized for body weight (VTBW), was increased. The mean inspiratory flow (VTBW/TI) was significantly augmented, but not as much as PO.1: in consequence, the effective inspiratory impedance was higher than predicted. Thus, as adults, COPD children had a greater inspiratory neural drive. In contrast to normocapnic COPD adults, they had a modified respiratory timing. PMID- 6927542 TI - A micro double capillary method for rheologic measurements of lower airway secretions. AB - We modified the double capillary method of Philipoff et al. [23] to allow rheologic measurements of lower respiratory secretions. The system consists of a precision bore stainless steel capillary (0.58 mm i.d., 5 mm length), a glass capillary (0.92 mm i.d., 15 mm length) and a sample holding tube (1.5 mm i.d., 15 mm length). This series of capillaries is connected to a long polyethylene catheter which permits advancing the system through the inner channel of a fiberoptic bronchoscope, and the placing of the sample holding tube into the lower airways for the aspiration of secretions under direct vision. The required sample volume is 20 microliter. The capillary is then removed from the fiberoptic bronchoscope and placed on a microscope stage; the movement of the meniscus of the sample under an applied vacuum as well as the elastic recoil of the sample after release of the vacuum are measured at body temperature. From this procedure, apparent viscosity (na) and shear elastic modulus (G) are calculated. The accuracy of the method was verified in vitro by using standard viscosity oils and a polymer solution of known elasticity. In five normal conscious sheep, na ranged between 200-3000 poises (shear rate: 0.06-1.0 s-1) and G between 17-83 dyn X cm-2. The micro double capillary method was found adequate for direct rheologic measurements of lower airway secretions. PMID- 6927541 TI - Reference values for pulmonary tissue volume, membrane diffusing capacity, and pulmonary capillary blood volume. AB - Pulmonary tissue volume (Vti), carbon monoxide diffusing capacity, membrane diffusing capacity, pulmonary capillary blood flow and pulmonary capillary blood volume were measured in ninety (54 men and 36 women) healthy lifetime nonsmokers using an inert gas rebreathing technique. Prediction equations were generated using multiple linear regressions with height and age as the independent variables. Normalizing the data by dividing by functional residual capacity eliminated all sex differences. In contrast to the other variables, normalized pulmonary tissue volume did not correlate with any of the independent variables tested. Therefore, an average normalized Vti value can be recommended as a reference value PMID- 6927543 TI - Pharmacokinetics of oral and intravenous indomethacin in preterm infants. AB - The pharmacokinetic profile of indomethacin administered either orally or intravenously in 13 preterm infants with significant patent ductus arteriosus (PDA) is reported. 9 infants received oral indomethacin and 4 received intravenous therapy. Plasma half-life was significantly prolonged as compared to adult values and demonstrated significant correlation with gestational age. Mean half-life in neonates less than 32 weeks gestation was 17.2 (0.8) vs. 12.5 (0.5) h for neonates greater than 32 weeks gestation. Bioavailability of the oral dosage based on AUC was 13% but no difference was observed in the plasma protein binding or distribution volume of drug as compared to adult values. No serious complications could be attributed to the use of indomethacin at these dose levels in the premature infant. PMID- 6927544 TI - Pharmacokinetics of indomethacin in the premature infant. AB - Indomethacin (I) pharmacokinetics was evaluated in 6 premature infants who received the drug for treatment of patent ductus arteriosus. Administered by oral or rectal route, I (0.2 mg/kg/24 h X 3) was promptly absorbed with peak plasma concentrations attained within 1 and 3 h. The elimination of I appeared to follow two compartment open model kinetics, with terminal plasma half-lives ranging from 30 to 90 h. Apparent plasma clearance values were between 0.076 and 0.335 ml/min/kg. Ductal closure was observed in 4 of the 6 infants. Data point to a possible relationship between therapeutic effects and I plasma concentrations. PMID- 6927545 TI - Tissue distribution of morphine in the newborns of addicted monkeys and humans. Clinical implications. AB - The distribution of morphine in various tissues of 6 addicted monkey fetuses and in 2 infants of drug-dependent mothers (IDDM) show that significant concentrations of the drug are in the gastrointestines (tissue plus content), liver, cerebellum, lungs, heart, spleen and thymus. The high concentration of morphine in the gastrointestinal tract may be secondary to the excretion of the drug through the bile or by the repeated swallowing by the fetus of amniotic fluid which contains morphine (1.9 +/- 1.0 micrograms/dl). Meconium, taken from 2 IDDMs show a significant concentration of morphine for up to 2-3 days after birth. Thus, meconium is a useful material to analyze postnatally for the diagnosis of neonatal narcotic addiction. PMID- 6927547 TI - Influence of concurrent testosterone on the effects of methadone on male rats and their progeny. AB - This study was conducted to test the hypothesis that the adverse effects on progeny that result from administering methadone to male rats are mediated by a decrease in serum testosterone. Male rats were treated with methadone HCl, 10 mg/kg/day for 4 days while an equal number received the same dose plus testosterone propionate, 2.5 mg/kg/day. Neonatal mortality was significantly lower among the progeny of sires which had received the testosterone, 22/132 vs. 33/101, x2 = 8.13, p less than 0.01. The mean body weight at weaning of the progeny of sires treated with methadone plus testosterone was about 4 g lower (p less than 0.01) than that of the progeny of sires which had received methadone only; one-half of this variability was attributable to the greater number of survivors in the former group. Testosterone administered concurrently with methadone to sires resulted in significant reductions in the weights of their testes and adrenals, but increased weights of their seminal vesicles. It was concluded that administration of testosterone concurrent with methadone by preventing dysfunction and/or atrophy of the accessory sex organs of the sire, may have been responsible for the improved neonatal survival of their offspring. PMID- 6927546 TI - Multiexponential elimination of gentamicin. A kinetic study during development. AB - The long-term disposition of gentamicin (up to 100-240 h) was studied in 13 premature newborns (33 weeks mean gestational age) and in 7 infants and children (1 month to 8 years). The data fitted bi- or triexponential curves with terminal half-lives averaging 51 and 37 h. Newborns showed lower values of body clearance, central compartment and steady state volumes of distribution than infants and children (respectively, 12.8 vs. 50.4 ml/min/1.73 m2, 9.03 vs. 17.5 liters/1.73 m2, and 15.7 vs. 35.5 liters/1.73 m2). The ratio between the amount of gentamicin predicted at steady state in the tissue compartment and in the total body was also significantly lower in newborns than in the older group (0.4 vs. 0.52). These data provide pharmacokinetic demonstration of an age dependence in gentamicin tissue distribution and excretion during the early stages of human development. PMID- 6927548 TI - Pharmacokinetics and echocardiographic effects of digoxin in low birth weight infants with left-to-right shunting due to patent ductus arteriosus. AB - Serum digoxin (DIG) levels, timed urine and M-mode echocardiograms were performed in 9 low birth weight infants with left-to-right shunting due to patent ductus arteriosus treated with DIG (40 micrograms/kg in 3 and 20 micrograms/kg in 6). Half the DIG was given initially and a quarter at 8-hourly intervals. Serum DIG levels at 24 h (1.8-7.0 ng/ml) were similar in both dose groups. One infant in the 40 micrograms/kg dose group developed Wenckebach phenomenon. Left atrial to aortic root ratio fell within 30 min and remained reduced during the ensuing 24 h (p less than 0.025). There were no significant changes in the other echocardiographic measurements. Half-life of distribution and elimination of DIG were 1.04 +/- 0.46 and 15.25 +/- 0.36 h. The alpha-phase volumes of distribution (VD) differed between the 40 and 20 micrograms/kg dose groups (2.28 +/- 0.05 vs. 1.33 +/- 0.66 liters/kg, p less than 0.025). The beta-phase VD (4.25 +/- 0.61 and 2.76 +/- 0.99, respectively) were similar. Mean urinary DIG clearance was 13.1 +/ 3.2 ml/min/1.73(2). PMID- 6927549 TI - Right hemisphere superiority in the recognition of famous faces. AB - Words and famous faces were tachistoscopically presented in bilateral view to normal right-handed subjects. A left visual field advantage was obtained for famous faces whether naming or recognition from an array was required and a right visual field advantage was obtained for words. While the finding of a left visual field advantage for the recognition of famous faces is consistent with studies of face recognition deficits in brain-damaged patients, a right visual field advantage for the recognition of famous faces has recently been reported in normal subjects. Possible explanations for this discrepancy are discussed. PMID- 6927550 TI - Verbal-manual time sharing in children as a function of task priority. AB - Eighty-three normal, right-handed children performed unimanual finger tapping recitation of a tongue twister, and both tasks concurrently. Trade-offs in dual task performance were measured as the priority assigned to each task was manipulated. Irrespective of task priority, speaking interfered to a greater degree with right-hand tapping than with left-hand tapping, but the effect of tapping upon verbal production and speech errors was not lateralized. The asymmetric effect of speech upon tapping, which was seen in 85.5% of the children, cannot be attributed to the disparity between hands in baseline tapping rate. The findings suggest that time-sharing asymmetry reflects cerebral lateralization of speech, but only some of the results would be predicted on the basis of a functional distance principle of cerebral organization. PMID- 6927551 TI - Qualitative aspects of pantomime recognition defect in aphasia. AB - This study investigated the performance pattern of aphasic patients on a pantomime recognition test in which one of the four response alternatives was an object semantically related to the correct choice. Aphasics with defective pantomime recognition made 71% of their total errors on the semantic foils, and for the majority of such patients, semantic errors represented 80 to 100% of total errors. Only aphasics with objective evidence of confusion failed to make highly frequent semantic errors. The findings suggest that most aphasics who fail pantomime recognition are impaired because of semantically vague understanding of the pantomimes' intended meaning rather than complete lack of understanding of the pantomime. PMID- 6927552 TI - A dissociation of right and left hemispheric effects for recognizing emotional tone and verbal content. AB - Emotionally intoned sentences (happy, sad, angry, and neutral voices) were dichotically paired with monotone sentences. A left ear advantage was found for recognizing emotional intonation, while a simultaneous right ear advantage was found for recognizing the verbal content of the sentences. The results indicate a right hemispheric superiority in recognizing emotional stimuli. These findings are most reasonably attributed to differential lateralization of emotional functions, rather than to subject strategy effects. No evidence was found to support a hypothesis that each hemisphere is involved in processing different types of emotion. PMID- 6927555 TI - Dementia in Parkinson disease: a neuropsychological analysis. AB - An extensive set of neuropsychological measures was administered to 60 Parkinson's disease patients and age-, sex-, and education-matched controls in order to investigate the nature and prevalence of the cognitive deficit in the disease. Parkinsonian patients performed significantly poorer on all measures with the exception of tests for apraxia and object recognition, and on a test of vocabulary knowledge. Discriminant analysis of the test data revealed that over 93% of patients are impaired relative to matched controls, but that assigning a prevalence rate for dementia in the disease may be difficult due to the continuous distribution of cognitive deficits. PMID- 6927553 TI - Synesthesia. II. Psychophysical relations in the synesthesia of geometrically shaped taste and colored hearing. AB - The psychophysical function in two synesthetic subjects, one with geometrically shaped taste and the other with colored hearing, is investigated. Each synesthete is compared with three control subjects. Pilot studies are used to construct appropriate response domains. Compared to controls, synesthetes give a restricted set of responses that are also asymmetric with respect to the range of choices available in various subsets of the response domain. A combination of absolute and relative effects is also distinctive of synesthetic percepts. It is concluded that synesthesia is a distinct phenomenon unlike ordinary mediated associations, and occupies an intermediate position in the range of simple to complex brain mechanisms. PMID- 6927554 TI - Short-term memory performance in the absence of phonological coding. AB - These experiments examined the short-term memory performance of an aphasic patient with posterior damage who shows a selective deficit in phonological coding. In recognition memory tests, the patient relied on both visual and semantic coding, and often showed an essentially normal level of accuracy. However, for memory sets consisting of four function words, his performance was quite impaired. Also, his retention of order information was far below that of normal controls. The implications of these deficits in short-term memory for language comprehension and production are discussed. PMID- 6927556 TI - Processing the intensity of dichotic syllables. AB - Subjects were required to match the intensity levels of the left- and right-ear members of dichotically presented nonsense syllables. When subjects matched the overall average intensities of a sequence of differing dichotic pairs no ear differences were observed. When repetitions of single dichotic pairs were matched right-ear syllables were judged louder than left-ear syllables. The results support a model predicting left-hemisphere superiority in a task permitting higher-level encoding of speech input. PMID- 6927557 TI - Handedness patterns in deaf persons. AB - The handedness patterns of 226 deaf high-school and college students were compared to those of 210 college students with normal hearing. Both groups evidenced many more right-handed than left-handed members, as determined by responses to a hand preference questionnaire and performance on an activity test battery. There was, however, a significantly higher incidence of left-handedness among the deaf subjects than among the hearing. Moreover, the left-handed deaf students were found to be less likely to have deaf relatives, and to have been introduced to sign language later in their development than the deaf student population as a whole. These findings were interpreted as showing that age of acquisition of language was related to the development of handedness patterns, whereas auditory processing experience probably was not. PMID- 6927559 TI - Recall failure following successful generation and recognition of responses by alcoholic Korsakoff patients. AB - Amnesic Korsakoff patients and controls were presented with twelve words, each shown individually in the presence of a weak associate. They were then asked to freely associate to 12 other words that were strong associates of the to-be remembered (TBR) words. The Korsakoff patients generated, and were able to recognize, as many of the TBR words as the controls. Yet, in spite of this recognition ability, these same patients were subsequently unable to recall the critical TBR words when the weak cues were again presented. A follow-up study found that the same recognition results could be obtained with Korsakoffs months after initial presentation suggesting that the patients might initially have "recognized" the most highly associated words simply because they represented the most probable choices. Intermediate association prompts failed to generate correct responses. It was hypothesized that the Korsakoff patients cannot restructure their semantic associative hierarchy during input in such a way as to become sensitized to other than the strongest associates as prompts during recall. PMID- 6927558 TI - The relationship between birth stress and writing hand posture. AB - Variations in handwriting posture (inverted versus noninverted) were measured in 1203 individuals for whom birth histories, based upon retrospective maternal reports, were available. A history of birth complications was associated with an increased incidence of inverted handwriting posture. Effects interacted with sex and hand preference; the largest difference in handwriting posture between the birth-stressed and non-birth-stressed groups occurred in left-handers and in males. PMID- 6927560 TI - Impairment of voice and face recognition in patients with hemispheric damage. AB - Voice and face recognition were tested in 21 left- and 9 right-hemisphere-damaged patients. Test materials were photographs and recordings of famous political and entertainment personalities. Pathological face recognition (prosopagnosia) and voice recognition (phonagnosia) were both significantly more prevalent in the right-hemisphere group. Only one instance of prosopagnosia and one of phonagnosia were observed in the left-hemisphere group, all of whom were aphasic. Of the right-hemisphere cases, there were four instances of each agnosia, with three patients showing a dual impairment. These findings are discussed in relation to differential modes of processing by the two cerebral hemispheres. PMID- 6927561 TI - Regional cerebral blood flow and verbal memory after chronic exposure to organic solvents. AB - Regional cerebral blood flow (rCBF; 133Xe-inhalation method) was investigated in 32 industrial workers (age: 51 +/- 9 years) who had been exposed to organic solvents during an average of 24.5 years. The measurements were made at rest and during learning of associated word pairs. The resting flow level was 17% lower than expected for normal subjects of similar age and the activation-induced changes of rCBF during the test lacked the frontal activation normally seen. Significant correlations between age, length of exposure, and rCBF level were found. In order to control for the age factor, results were also calculated from two subgroups of similar age but with very different levels of exposure (13 and 31 years of average exposure). The two groups differed only slightly in resting rCBF. A marked difference was, however, seen during activation, with significant post-central flow increases recorded in the lower-exposed group only. The results indicate the potential of the rCBF method for elucidating functional cortical changes related to neurotoxic effects of organic solvents. PMID- 6927562 TI - Focal changes in cerebral blood flow produced by a test of right-left discrimination. AB - A sensorimotor control activation task was used to isolate the focal cerebral blood flow changes resulting from the visual and cognitive processing of a right left discrimination task. Eleven normal right-handed males participated. The sensorimotor control task produced significant bilateral increases in flow in most cortical channels. Significant bilateral parieto-occipital activation was found for the right-left discrimination task over and above the flow changes produced by the sensorimotor control task. The left occipital flow increase resulting from the right-left discrimination task was found to be negatively related to task performance. An inverse relationship was also found between WAIS Performance IQ and the blood flow change in the left parietal channel. These results suggest areas for further testing concerning potential individual differences in cognitive processing during the performance of a right-left discrimination task. PMID- 6927563 TI - Hemispheric asymmetry, early visual processes, and serial memory comparison. AB - Observers indicated whether a single probe letter presented to the left visual field/right hemisphere (LVF-RH) or to the right visual field/left hemisphere (RVF LH) matched one of two, three, four, or five set letters in both name and case. For positive trials during the initial experimental session, the slope of the linear memory set size reaction time function was increased by perceptually degrading the probe letter on LVF-RH trials, but not on RVF-LH trials. In addition, perceptual degradation of the probe letter increased the intercept of the memory set size function more on RVF-LH trials than on LVF-RH trials. During subsequent experimental sessions, the same pattern of intercept results was obtained but perceptual degradation of the probe no longer changed the slope for either LVF-RH or RVF-LH trials. However, the slopes were uniformly lower on RVF LH trials than on LVF-RH trials. The major results are consistent with hypothesized right-hemisphere efficiency for early processing stages and left hemisphere efficiency for serial processing of alphanumeric information. The results further illustrate the importance of separating stages of processing in studies of cerebral laterality and indicate that the relative difficulty of the various stages can be a determinant of laterality results. PMID- 6927564 TI - Ear asymmetry in recognition of unfamiliar voices. AB - Female right-handed subjects were presented with a memory set consisting of five unfamiliar female voices. They were then tested with a recognition procedure in which samples of voice, memory set or novel, 2 or 4 sec in duration, were heard in one ear and a competing noise stimulus was heard in the other ear. There was an overall left-ear advantage in accuracy of recognition. This advantage held particularly for identifications of memory-set voices in the second half of trials. Internal analyses indicated that the left-ear advantage could not be attributed to greater retroactive interference during right-ear presentation. Congruent with studies of recognition of unfamiliar faces, the findings suggested right-hemisphere superiority in the recognition of unfamiliar voices. PMID- 6927565 TI - Temporal order judgments with amnesia. AB - The hypothesis that patients with anterograde amnesia fail to recognize the temporal relations among recognizable past events was evaluated. Experiment 1 showed that order recognition for words in a list was at chance levels even though event recognition was significantly above chance. The same pattern did not obtain for intact adults. Experiment 2 examined event and order recognition for news events. Amnesics' event recognition for news events was quite accurate and comparable to controls, yet their order recognition was significantly below that of controls, again at chance levels. It is argued that the failure to encode the temporal relations among events has broad consequences for memory performance in general. PMID- 6927566 TI - Further observations on the nature of prosopagnosia. AB - Two new cases of prosopagnosia are described and compared with pertinent clinical material from the English language literature. The interpretation of this disorder most compatible with the clinical data appears to us to be that there is an underspecification of visuoperceptive information preventing both the formation of significant face images and the retrieval of well-known face memoranda existing within a relatively intact visual remote memory store. Failure of formation of immediate memoranda of similarly complex visual images is also commonly observed but does not seem to be a requirement for the symptom of prosopagnosia. Conceptualizing this abnormality as simply a material specific visual agnosia of images beyond the classifier level would still appear to be acceptable if less informative. PMID- 6927567 TI - Dichhaptic laterality and field dependence. AB - Relationships among laterality, field dependence, and sex were investigated using right handed subjects. Dichhaptic measures of laterality showed a significant left-hand advantage for the discrimination of irregular shapes. No significant relationships were found between laterality and sex or sex role perceptions nor between laterality and field dependence. A modality of response effect on the laterality task was interpreted in terms of the functional cerebral space principle. PMID- 6927569 TI - Hemispheric memory for random forms revisited. AB - Hemispheric short-term memory was studied by projecting complex random forms that varied in their verbal association strength to the left and right hemispheres. Male and female subjects responded same or different to a centrally presented memory test stimulus which occurred 0, 5, 10, or 20 sec after the target item. Reaction time for both response judgments was significantly shorter for right hemisphere presentations over all memory intervals. For both performance measures, response judgment interacted with the length of memory interval and the verbal association value of the stimulus items. No hemispheric differences were observed as a function of subject sex. Hemispheric memory for complex forms appears primarily dependent upon task processing demands rather than stimulus factors when response time is used to measure recognition under tightly controlled conditions. PMID- 6927568 TI - Reversal operations after brain damage. AB - The ability to perform reversals--that is, the appreciation of the relationship between original and transformed states of knowledge--is critical to human thought processes. In order to assess whether a number of "special-purpose processors" are responsible for reversal operations, depending on the particular context in which the reversal is couched, or whether a single "core processing mechanism" subserves a critical aspect of reversal operations regardless of the specific context, patients with localized brain damage were asked to solve eight reversal problems. Visual and auditory reversals mediated by linguistic and non linguistic symbol systems were presented. The findings demonstrate that patients with insult to the anterior portion of the right hemisphere encounter more difficulty performing reversals than patients with right posterior insult, Broca's aphasics, and fluent aphasics. This is regardless of the symbol system mediating the reversal, regardless of the modality of presentation, and regardless of the amount of available processing time. Subjects with insult to the posterior region of the left hemisphere or the right hemisphere also exhibit some difficulty solving reversal problems, although their difficulties appear modality specific. These data lend support to the claim that a core processing mechanism may play a critical role in the performance of reversal operations. PMID- 6927570 TI - Emotional stimulation, defensive orientation, and hemispheric activation. AB - Lateral eye movements (LEM) were measured for 32 right-handed subjects while responding to questions rated for verbal and visual-spatial cognitive content and for varying levels of emotionally stimulating content. The results indicated that eye movements were distributed to the right and left in response to verbal and spatial items, respectively, and that emotional content enhanced leftward responding. In addition, the defensive style of subjects, as measured by a defense mechanism inventory, interacted with the cognitive and affective dimensions of questions and was a determinant of LEM. PMID- 6927571 TI - Visual-field differences in picture-word interference. AB - Picture-word interference refers to the fact that if a picture (i.e., line drawing) is presented centrally with a word superimposed, picture-naming latency is longer than if that same picture is presented alone. This phenomenon, like the Stroop phenomenon, seems to be strongly influenced by the nature of the to-be ignored word. That is, if the word names a member of the picture's semantic category additional interference is observed; however, if the word is replaced by a phonetically unviable consonant string interference is reduced. In the present experiments these effects were examined in the situation where the picture-word stimuli were presented unilaterally in either the left or right visual field. For right-visual-field presentations, phonetic and semantic factors both influenced performance just as in central presentations. As such, these results can be satisfactorily explained in terms of response competition processes. However, the results for the left-visual-field presentations were quite different. Although substantial interference was observed for all types of stimuli, the amount of interference was essentially independent of the linguistic nature of the superimposed letter string. These results do not appear to be explainable in terms of response competition processes. Instead, it is suggested that the best way to explain these results is in terms of the perceptual capabilities of the right hemisphere. PMID- 6927572 TI - The effect of lateral visual fixation on response latency to verbal and spatial questions. AB - The results of several studies have suggested a relationship between lateral eye movements and contralateral hemispheric activation or ipsilateral inhibition. The present study investigated the effects of lateral and central eye fixation on response latency to verbal and spatial questions. Response latencies for verbal questions were significantly longer when subjects fixated to the left or centrally, as compared to the right. On spatial questions, response latencies were significantly longer in the right fixation condition than in the other conditions. The results indicate that visual fixation ipsilateral to hemispheric activation is related to slower problem solving, and suggest that eye movements during cognitive activity may have functional significance. PMID- 6927574 TI - The abuse of legal drugs. PMID- 6927573 TI - Temporal stability and predictive validity of self-assessed hand preference with first and second graders. AB - The test-retest reliability and predictive validity of a five-item hand preference questionnaire (writing, drawing, throwing a baseball, brushing teeth, and cutting with scissors) were investigated in a sample of 80 children attending first and second grade. After 1 month, 81% of the second choices were the same as the first choices. There were interitem differences in the reliabilities of the five items. Writing and drawing hand exhibited the greatest degree of temporal stability. Writing hand was the one task which was significantly related to visual field bias as indexed by a face perception task. PMID- 6927577 TI - Psychoactive drug use among overweight psychiatric patients: problem aspect of anorectic drugs. AB - The relationship between anorectic drug (stimulant) treatment and subsequent drug abuse in overweight individuals has often been discussed but seldom systematically studied. One hypothesis is that anorectic treatment promotes the likelihood of drug-abuse patterns. The present study involved a group of overweight psychiatric patients (n = 91) who were compared on the basis of whether or not they had used anorectic drugs in the past year and also whether or not they were currently using any form of psychoactive drugs. It was found that the use of anorectic drugs was mainly associated with weight problems, such as dieting difficulties, but not with amount of overweight. Anorectic use and other weight-problem variables do not seem to be strongly related to the psychiatric patient's drug problems. PMID- 6927581 TI - Problems and issues encountered in drug abuse research. PMID- 6927583 TI - Family life and levels of involvement in an adolescent heroin epidemic. AB - Family life was studied in relation to different levels of heroin involvement, use of other drugs, and deviant behavior in a suburban, shite, adolescent population. Family elements included: emotional closeness, cohesive bonds, control, and conflict. More elements of family life were related to heroin use for females than for males. The relationship with the cross-sex parent had the strongest impact on male and female heroin users. The same family variables which related to male heroin use were related to his use of other hard drugs and deviance. Family variables were not as strong predictors for other drug use and deviant behavior in females. PMID- 6927584 TI - [Note on Anopheles of the Tassili n'Ajjer]. PMID- 6927582 TI - Just for fun: alcohol and the college student. PMID- 6927585 TI - [Note on the phlebotome Diptera, Psychodidae of Tassili n'Ajjer]. PMID- 6927586 TI - [Note on Simulium of Tassili n'Ajjer]. PMID- 6927587 TI - [Replication of adenovirus type 5]. PMID- 6927588 TI - [Immunosuppressive response to antidiphtheria vaccine in animals infected by Plasmodium berghei yoelii]. PMID- 6927589 TI - [Immunosuppressive response to antitetanus vaccine in mice infected with Plasmodium berghei yoelii]. PMID- 6927590 TI - [Effect of adjuvants on the immunosuppressive effect of the parasitic action of Plasmodium berghei yoelii]. PMID- 6927591 TI - [Visceral leishmaniasis in an endemic bouton d'orient zone apropos of 2 cases]. PMID- 6927592 TI - [Values of biochemical parameters of hydatid fluids in different hosts]. PMID- 6927594 TI - Inflammatory bowel disease. PMID- 6927593 TI - [A new case of hepatic distomatosis in Algeria]. PMID- 6927595 TI - Comprehensive management of spinal cord injury. PMID- 6927596 TI - Gallstones and other biliary diseases. PMID- 6927598 TI - CPR: basic life support. PMID- 6927597 TI - Hypertension. PMID- 6927600 TI - Experimental immunology of Guillain-Barre syndrome. PMID- 6927599 TI - A polio-like syndrome in adults following acute hemorrhagic conjunctivitis. PMID- 6927602 TI - Myasthenia gravis: signs, symptoms, diagnosis, immunology, and current therapy. AB - Myasthenia gravis is a neuromuscular disease that presents clinically as fluctuating weakness of one or more skeletal muscle groups. Weakness becomes more severe with exercise and improves with rest. The disease is caused by an autoimmune reaction at or near the post-synaptic nicotinic acetylcholine receptor. The results of this immune reaction are the lytic destruction of the post-synaptic membrane and a reduction in the number of acetylcholine receptors. Myasthenia gravis can be diagnosed by repetitive exercise of the involved muscles, administration of edrophonium (Tensilon), electrophysiologic testing, or demonstration of anti-acetylcholine receptor antibodies. When the myasthenic weakness is mild or limited to the extraocular muscles, it may be treated with acetylcholinesterase inhibitors. When the weakness is more severe and/or more generalized, immunotherapy is most often indicated. Prednisone or prednisone plus thymectomy is the most frequently used form of immunotherapy. Azathioprine, 6 mercaptopurine, plasmapheresis, or gamma globulin injections are other immunotherapeutic options that may be useful in selected patients. A large number of drugs may precipitate or exacerbate myasthenic weakness. PMID- 6927601 TI - Metronidazole: in vitro activity, pharmacology and efficacy in anaerobic bacterial infections. AB - Metronidazole is a 5-nitroimidazole that has selective activity against anaerobic microorganisms, including bacteria and protozoa. Intravenous metronidazole has recently been approved by the U.S. Food and Drug Administration for the treatment of serious anaerobic bacterial infections. It is usually bactericidal at low concentrations, and its spectrum of activity encompasses almost all anaerobic bacteria and some capnophilic organisms. Anaerobic bacteria known to be resistant to metronidazole include occasional anaerobic cocci, some nonsporulating gram positive bacilli and propionibacterium. Metronidazole is the most active antimicrobial agent against Bacteroides fragilis, the most resistant of anaerobic bacteria. Kill-curve studies demonstrate that there is a 2 to 5 log decrease in the number of colony forming units of B. fragilis and Clostridium perfringens within one hour. The only well documented metronidazole-resistant strain is a B. fragilis isolated from the normal flora of a patient on long-term metronidazole therapy for Crohn's Disease. Metronidazole resistance in Trichomonas vaginalis has recently been described in a few strains that are able to survive at increased oxygen tensions. Metronidazole has been shown to be efficacious in certain protozoal infections including trichomonal vaginitis, extraintestinal amebiasis, and giardiasis. Clinical studies have shown metronidazole to be efficacious in the therapy of a variety of anaerobic infections, including non traumatic brain abscesses, intraabdominal sepsis, pelvic suppuration and necrotizing soft tissue infections. There have been disappointing results in the therapy of anaerobic pleuropulmonary infections with a number of superinfections caused by aerobic bacteria. Since metronidazole lacks any activity against aerobic bacteria, it must be combined with other agents, usually aminoglycosides, in the treatment of mixed infections involving anaerobic and aerobic bacteria. PMID- 6927603 TI - Reappraisal of guidelines for pharmacokinetic monitoring of aminoglycosides. AB - The rationale for pharmacokinetic monitoring of aminoglycosides is critically reviewed. Retrospective studies suggest that for optimal antibacterial effect, peak serum gentamicin concentrations should exceed 5 micrograms/ml, despite the fact that these concentrations are indirect measures of the concentration of drug at the site of infection. When quantitative results of antimicrobial susceptibility are known (e.g. MIC or MBC), limited data suggest that for most infections, the peak serum aminoglycoside concentration should exceed the minimum inhibitory concentration by four-fold. However, the optimal duration for which the serum concentration should exceed the MIC or MBC during each dosing interval and the detrimental effect of prolonged subinhibitory drug concentrations have not been evaluated. Furthermore, the immunological competence of the host and the pathogenicity of the infecting organism are important factors in achieving antibacterial response. Using serum creatinine as an indirect and relatively late indicator of nephrotoxicity, nadir gentamicin concentrations greater than 2 micrograms/ml may predispose patients to develop nephrotoxicity. In addition, recent information indicates that patients who accumulate excessive amounts of aminoglycosides in their tissues may be at higher risk for developing nephrotoxicity; these patients may be identified based on the extent of accumulation in their nadir concentrations with continuous dosing. The aminoglycosides diffuse into the inner ear fluids slowly and diffuse out with a half-life of decline in inner ear fluid concentrations slower than that in serum. High transient peak serum concentrations probably do not contribute significantly to the risk of ototoxicity. However, there is evidence from early clinical trials, studies using continuous infusions of aminoglycosides, and animal studies indicating that elevated nadir serum concentrations relate to the development of ototoxicity. There is considerable interpatient variability in the peak serum concentration, even when identical dosages based on body weight or surface area are administered. Similarly, the half-life for decline in serum concentrations is highly variable from patient to patient, even in patients with stable normal renal function. Absorption after intramuscular administration is reliable in most patients, although critically ill patients may experience erratic absorption. The distribution of aminoglycosides is altered in obese patients because of differences in extracellular fluid content between fat and other tissues.(ABSTRACT TRUNCATED AT 400 WORDS) PMID- 6927604 TI - Glycerol: a review of its pharmacology, pharmacokinetics, adverse reactions, and clinical use. AB - Glycerol is a potent osmotic dehydrating agent with additional effects on brain metabolism. In doses of 0.25-2.0 g/kg glycerol decreases intracranial pressure in numerous disease states, including Reye's syndrome, stroke, encephalitis, meningitis, pseudotumor cerebri, central nervous system tumor, and space occupying lesions. It is also effective in lowering intraocular pressure in glaucoma and shrinking the brain during neurosurgical procedures. Hyperosmolality with rebound cerebral overhydration is of concern, especially in patients with altered blood brain barriers. They may be avoided if glycerol is administered on an intermittent rather than a continuous basis. Intravascular hemolysis does not occur with oral use. When administered intravenously, hemolysis can be minimized by using glycerol 10% in dextrose 5% with normal saline at rates of 6 mg/kg/min or less. However, intravenous doses of 1-2 g/kg every 2 hr can be administered safely in severe cases of elevated ICP. In such patients, glycerol serum concentration, serum osmolality and ICP monitoring are required to optimize glycerol therapy. PMID- 6927605 TI - Mechanism of action, pharmacokinetics, adverse effects, and therapeutic uses of amiloride hydrochloride, a new potassium-sparing diuretic. AB - Amiloride hydrochloride is a new, orally administered, potassium-sparing diuretic with mild natriuretic and diuretic properties. Its primary site of action is the distal tubule of the nephron where it selectively blocks sodium transport, thereby inhibiting sodium-potassium exchange. The mechanism of action of amiloride is independent of aldosterone. It is excreted unmetabolized in the urine and feces. Peak serum levels are seen at three hours, and the serum half life is six hours. The drug can probably be safely administered to patients with hepatic dysfunction but should be used cautiously, if at all, in patients with renal insufficiency. Amiloride is well tolerated, and serious toxicity is rare. It should prove useful in edematous states and hypertension. When amiloride is used in fixed combination with a thiazide diuretic the risk of hypokalemia is minimal. PMID- 6927607 TI - Messenger RNA and ribosomes in protein synthesis. PMID- 6927606 TI - Metronidazole in anaerobic bacterial infections. PMID- 6927608 TI - [Clinico-statistical features of perinatal and early neonatal mortality]. AB - Perinatal and neonatal mortality rates are considered to be among the most sensitive measures available for monitoring the health of population and consequently have been assumed, too, to reflect primarily the capacity of the obstetricians and pediatricians. Perinatal mortality is here defined as stillbirths (or late fetal deaths) plus early neonatal deaths, that is, it includes fetuses born dead after 28 completed weeks of pregnancy and liveborn infants who died before the completion of the first week after birth. This report is concerned with the variation in neonatal mortality observed at the Istituto Clinico di Puericultura, Bologna University in a period from 1971 to 1981 and in perinatal mortality from 1976 to 1981 only. In this period reductions in stillbirths (from 12.5% to 7.8%) and early neonatal mortality (from 13.2% to 7.0%) are recorded. The decrease in the perinatal mortality rate, which occurred at the Obstretic-Neonatal Unit of Bologna University (dropping from 25.6% in 1976 to 14.8% in 1981) may be attributed to a comparable reduction in stillbirths and early neonatal mortality due to better health services and a more modern pattern of medical care. More attention must be given to that particular group of newborn babies weighing 1,500 gm or less (VLBW Infants) which accounted for about 40% of all the neonatal deaths. PMID- 6927609 TI - [Synthesis, cytostatic activity and mechanism of action of N glycosylhalomethylazoles. A new class of alkylating agents]. AB - A model to produce a new type of alkylating agents having anti-cancer activity is described. They consist of a halomethyl-azol group of the benzyl type as alkylating center, and a sugar moiety as a carrier fragment. Alkylating nucleosides were produced as halomethyl-pyrazole, -imidazole, 1.2.3-triazole, and 1.2.4-triazole derivatives following the model, and tested upon Ehrlich ascites cancer and P-388 lymphocytic leukemia. PMID- 6927613 TI - Exporting British expertise. PMID- 6927614 TI - OH services to small industries. PMID- 6927611 TI - [Diagnosis of certain forms of rheumatism]. PMID- 6927610 TI - [Computer technic for measurement of the pulmonary transfer of carbon monoxide]. AB - An informatic method is described for accurate on-line computation and recording of pulmonary transfer for carbon monoxide (steady state CO uptake with alveolar CO measured from end-tidal determination of gas) using fast response transducers for ventilatory flow and carbon monoxide tension. Special procedures for time alignement of flow and tension signal, and for determination of PACO by microcomputer, are described. The accuracy of the method was studied under informatic and non informatic methods PECO, PACO and TLCO values are in good agreement with those obtained by the conventional non-informatic method. PMID- 6927612 TI - Cadmium: protection from its effects. 2. PMID- 6927615 TI - Self-concept and coping in adolescents with a physical disability. PMID- 6927616 TI - Nursing and the terminally ill: beliefs, attitudes, and perceptions of practitioners. PMID- 6927617 TI - Assessment of relationship between self-concept and body image using multivariate techniques. PMID- 6927618 TI - The attitudes of psychiatric nursing staff toward staff development programs: a quasi-experimental analysis. PMID- 6927619 TI - Nursing therapy of an incest victim. PMID- 6927620 TI - Tool development for profiling the attitude of clients with schizophrenia toward their medication, using Fishbein's expectancy-value model. PMID- 6927621 TI - The status of the Philippine Nursing Act of 1982. PMID- 6927622 TI - Employment opportunities and the nursing profession. PMID- 6927623 TI - The nursing curriculum: a reassessment. PMID- 6927624 TI - Educational preparation and other individual-related factors associated with performance of specific functions of practicing nurses in different work settings. PMID- 6927625 TI - Statement of members of the health care system on the protection and promotion of breastfeeding in the Philippines. PMID- 6927626 TI - The nurse: an agent to meaningful aging. PMID- 6927627 TI - Legal aspects of school administration. PMID- 6927628 TI - Urban health development through primary health care. The Manilla experience. PMID- 6927630 TI - Professional assertiveness towards greater and more effective service to the Filipino people. PMID- 6927629 TI - The challenge for professional assertiveness. PMID- 6927631 TI - Perceived intrusions into territorial and personal space as anxiety-producing factors to hospitalized patients: implications to nursing. PMID- 6927632 TI - Framework skills for nursing day care and early childhood managership (how to do it and survive sane and sound). PMID- 6927633 TI - Nursing assertiveness in primary health care. PMID- 6927634 TI - Comparison of the nephrotoxicity of oral neomycin and ampicillin in rats. PMID- 6927635 TI - Involvement of liver in tuberculosis. PMID- 6927636 TI - Stomach in tropics. PMID- 6927639 TI - In vitro comparison of clindamycin and pirlimycin (U-57930E) activity against Staphylococcus aureus. AB - The activities of clindamycin and its derivative, pirlimycin (U-57930E), were compared against 100 strains of Staphylococcus aureus, using a microtiter broth dilution technique. Minimal inhibitory concentrations demonstrated that pirlimycin was comparable to clindamycin but offered no increase in activity against either methicillin-susceptible or methicillin-resistant S. aureus. PMID- 6927637 TI - Bactericidal activity of antibiotics against Legionella micdadei (Pittsburgh pneumonia agent). AB - The bactericidal activity of five antibiotics for Legionella micdadei was determined by the construction of time-kill curves. Erythromycin, rifampin, penicillin G, cephalothin, and gentamicin were bactericidal for L. micdadei at readily achievable concentrations. The minimal bactericidal concentrations, defined as those producing 99.9% killing within 24 h, were: erythromycin, 4.6; rifampin, 0.13; penicillin G, 0.25; cephalothin, 2.5; and gentamicin, 0.25 micrograms/ml. The ratios of the minimal bactericidal to minimal inhibitory concentrations for these antibiotics ranged from 1 to 8. Thus, the poor in vivo activity of beta-lactam and aminoglycoside antibiotics against L. micdadei cannot be ascribed to a lack of killing by these agents. PMID- 6927640 TI - Toxicity of 29 plasticizers to HeLa cells in the MIT-24 system. AB - The toxicity to HeLa cells of 29 plasticizers was determined in the MIT-24 test system. The 7-day IC50 for HeLa cells varied from 260 to 1.5 g/l. Phthalates, adipates, sebacates, azelates and phosphates with long carbon chain alcohols were very non-toxic to the cells, probably due to insolubility in water of the compounds, while the citrates, some phosphates and the 2 polymer plasticizers had a higher toxicity to the cells. A comparison of the HeLa cytotoxicity with the toxicity in vitro to other cells for 7 plasticizers showed a similarity of the cytotoxicity to all cell types. A comparison of the HeLa cytotoxicity for 20 plasticizers with i.p. lethal dosage in rodents demonstrated a rough similarity of values, suggesting a toxicity in rodents of the compounds by toxic interference of the agents with basal functions and structures of tissues (basal cytotoxicity). Tissue culture studies of the cytotoxic mechanisms of the plasticizers therefore could reveal modes of toxic action in vivo. PMID- 6927641 TI - Ultrastructural evidence of pulmonary capillary endothelial damage from paraquat. AB - Because of lack of agreement concerning the toxicity of paraquat to the pulmonary microvasculature, we have undertaken an electron microscopic study of lungs of paraquat-treated rats. Rats were injected with paraquat or sterile water (controls) intraperitoneally; the animals were then killed at 24-h intervals for 10 days post-injection. In the control animals, lung ultrastructure remained normal throughout the study. In treated animals, the initial evidence of alveolar epithelial injury occurred 24 h post-paraquat. By 48 h, severe fragmentation and desquamation of membranous pneumocytes occurred, and both alveolar and interstitial edema were present. Epithelial damage was maximal 72-96 h post paraquat. Pulmonary capillary endothelial abnormalities were less extensive than the alveolar epithelial lesions. Endothelial damage was first observed 48 h post paraquat. In endothelial cells on the septal (thick) side of the capillaries, the number of pinocytotic vesicles was significantly increased (P less than 0.05) from 48 to 96 h post-paraquat. In endothelium adjacent to damaged epithelium, abnormalities included hydration, fragmentation, discontinuity, and widened intercellular junctions; these were maximal 72-96 h post-paraquat. Although other mechanisms are probably important, damaged pulmonary capillary endothelium seems to be a factor favoring paraquat-induced pulmonary edema. PMID- 6927638 TI - Resistance to beta-lactam antibiotics in Streptococcus faecium. AB - Clinical isolates of Streptococcus faecium are characteristically resistant to beta-lactam antibiotics. Two strains, selected for hypersusceptibility to penicillin, were derived from normally resistant isolates treated with novobiocin. These strains were also found to be hypersusceptible to other beta lactams. Differences in beta-lactam susceptibility between the original isolates and the hypersusceptible strains could not be attributed to alterations in penicillin-binding protein affinities, and no evidence of a relative permeability barrier was found in the resistant strains. Isolated cell membranes prepared from resistant strains were found to possess two protein bands which were absent or greatly diminished in the membranes of susceptible strains. Hypersusceptibility to beta-lactam antibiotics in these strains may be due to the absence or alteration of one or more cell membrane proteins distinct from the penicillin binding proteins of these organisms. PMID- 6927642 TI - In vivo cytogenetic effects of oil shale retort process waters. AB - The induction of cytogenetic effects by oil shale retort process waters from 3 types of pilot plant retorts were examined in murine bone marrow. Each of the process waters induced increased frequencies of structural aberrations in mice treated with 3 daily intraperitoneal injections of the waters. The same treatment had no effect on the frequency of sister chromatid exchanges. Mice given a 1% solution of an above-ground retort water ad libitum for 8 weeks consumed about 1 ml/kg per day of the process water and had a frequency of aberrations comparable to mice given the same dose intraperitoneally for 3 days. Transplacental exposure of C3H mouse embryos indicated that clastogenic compounds in the above-ground retort process water can cross the placenta and induce chromosomal aberrations in embryonic tissues. PMID- 6927643 TI - Thymic atrophy induced by acute exposure of 3,3',4,4'-tetrachloroazobenzene and 3,3',4,4'-tetrachloroazoxybenzene in rats. AB - The effects of 3,3',4,4'-tetrachloroazobenzene (TCAB) and 3,3',4,4' tetrachloroazoxybenzene (TCAOB) on lymphoid organs in male Sprague-Dawley rats were investigated in various acute exposure studies. Significant thymic atrophy was observed in rats 10 days after the i.p. administration of either compound (on days 1 and 5) at a dose of 25 mg/kg. When 8-week-old animals were studied, the relative thymus weight was reduced to 69% and 49% of the control value by the respective treatment of TCAB and TCAOB. In 2 groups of weanling rats the same dosage of TCAOB was able to reduce the relative thymus weight to 31% and 38% of the comparable control animals. In addition, TCAOB causes a decrease in the body weight gain and a decrease in the weights of major organs in the weanling animals. This toxic response cannot be explained solely on the basis of decreased food intake since qualitatively the same results were observed in a pair-feeding experiment. The involvement of glucocorticoid hormones was rejected as the underlying mechanism since adrenalectomy was found to provide no protection towards the degenerative effect seen upon the lymphoid tissues. This investigation constitutes the first study concerning the effects of these 2 environmental and occupational toxicants on lymphoid organs. PMID- 6927644 TI - Acute dermal toxicity of two quarternary organophosphonium salts in the rabbit. AB - Tetrabutyl phosphonium chloride and tetrabutyl phosphonium bromide were evaluated for their potential to cause primary dermal irritation and acute dermal toxicity in rabbits. Both chemicals were found to not only be severely irritating to skin, but the pure hygroscopic chemicals caused death in more than half the number of rabbits used in the primary dermal irritation tests. Further investigations revealed the single-application dermal LD50 of tetrabutyl phosphonium chloride (Bu4PCl) (using an ethylene carbonate (EC) vehicle) was 600 mg/kg for male rabbits and 500 mg/kg for female rabbits. The single-application dermal LD50 of tetrabutyl phosphonium bromide (Bu4PBr) (using the EC vehicle) was 700 mg/kg for male rabbits and 850 mg/kg for female rabbits. The dermal LD50 of pure undiluted Bu4PCl was 225 mg/kg for male rabbits. These data indicate that Bu4PCl and Bu4PBr represent a substantial acute dermal toxicity hazard. PMID- 6927648 TI - Hatching and lipid composition of chicks brain from eggs treated with 2,4 dichlorophenoxyacetic butyl ester. AB - Fertilized hen's eggs were painted, before starting incubation, with solutions of commercial 2,4-dichlorophenoxyacetic butyl ester, (0.8 mg, 3.1 mg, 6.3 mg, 9.4 mg and 12.1 mg of pure drug) in ether. Hatchability studies suggest that the fetotoxic effects observed are related to the drug concentration. There are no statistically significant differences between control and treated groups in body weight, cerebral wet, and dry weights and water content. Protein and total lipid levels are dose dependently decreased. Phospholipids are significantly diminished in the 6.3 mg of 2,4-dichlorophenoxyacetic butyl ester group. Gangliosides are increased while cholesterol and glycolipids are diminished; their decrease is inverse to drug concentration. A decrease in glycolipids suggests an alteration of the normal process of myelination. PMID- 6927647 TI - Effects of potassium dichromate on the cell cycle of an established human cell line (NHIK 3025). AB - The effect of K2Cr2O7 exposure on the cell cycle phases of the human cell line NHIK 3025 has been studied. Inhibition of cell proliferation was found to depend on the concentration and length of exposure. An effect on cell proliferation was observed 6-9 h after addition of K2Cr2O7, whereas cell death was not observed until 3-4 days later. The cells were most sensitive in G2 phase. After exposure to 8 mumol/l K2Cr2O7 the greatest prolongation of the cell cycle was in G2 + M phase, but an increase of S phase was also observed. No prolongation of G1 phase could be measured. Our results thus indicate that K2Cr2O7 delays progression through the cell cycle. PMID- 6927645 TI - Transplacental effects of carcinogens and non-carcinogens on activities of pyruvate kinase and lactate dehydrogenase as well as isozymic pattern of LDH in mouse lung. AB - The carcinogens, urethane (URTH), 3-methylcholanthrene (MCA) and dimethylnitrosamine (DMN) given to pregnant mice enhanced permanently the activities of pyruvate kinase (PK) and lactate dehydrogenase (LDH) in the lungs of offspring even well before the appearance of lung tumours. The noncarcinogenic analogues phenylurethane (PHUR) and pyrene (PYR), had no effect on PK or LDH activity. The non-carcinogenic pulmonary toxicant Paraquat (PAR) elicited only a temporary elevation in the activities of the enzymes tested. The H:M ratio of LDH sub-units in the lung tissue was permanently decreased by URTH administered transplacentally. PAR caused only a temporary decrease in the H:M ratio, while PHUR had no effect on the isozymic pattern of LDH. PMID- 6927649 TI - The pathophysiological profile of the acute cardiovascular toxicity of sodium fluoride. AB - The intravenous infusion of sodium fluoride (2 mg/kg X min) into anesthetized rats caused a progressive fall in arterial blood pressure, cardiac output, heart rate and peripheral resistance. Respiratory rate increased during the first 20 min of infusion resulting in increased oxygen and decreased carbon dioxide blood concentrations. Total body oxygen consumption decreased after 30 min of NaF infusion by 29%, whereas the respiratory quotient (RQ) increased from 0.8 to 1.06. Death occurred after a mean dose of 79.6 +/- 4.6 mg/kg NaF. The terminal cardiac event before death was atrioventricular block followed immediately by asystole. Artificial ventilation did not influence the cardiovascular and the lethal effects of fluoride infusion. The plasma concentrations of total and ionized calcium decreased upon NaF infusion. The infusion of extra calcium did not prevent NaF-induced cardiovascular failure but decreased plasma fluoride levels and increased the lethal dose of NaF by 17% (not significant). In isolated atria and perfused hearts in vitro, NaF decreased the force of contraction in a dose-dependent manner. In conclusion, cardiovascular failure resulting from the direct cardiodepressive and vasodilatating effects of fluoride (and not from respiratory depression or hypocalcemia) accounts for the lethal outcome of fluoride intoxication. PMID- 6927646 TI - Enhanced teratogenicity of orally administered lead in hamsters fed diets deficient in calcium or iron. AB - A preliminary investigation was carried out to determine if dietary deficiencies in calcium or iron enhance the embryotoxic and teratogenic effects of orally administered lead in hamsters. Females of experimental groups were given drinking water containing 0.05% or 0.1% lead acetate and a calcium or iron deficient diet for several weeks prior to and/or during pregnancy. The incidence of embryonic/fetal mortality and of abnormal fetuses was markedly increased in litters delivered from these animals near term (15th gestational day) compared with litters from control animals similarly exposed to leaded drinking water but fed complete diets. PMID- 6927651 TI - Failure of physostigmine in intoxications with tricyclic antidepressants in rats. AB - In experiments on rats there is a moderate antagonistic effect of physostigmine against intoxications with the tricyclic antidepressants (TAD) clomipramine, desipramine and imipramine, respectively. During the first hours after TAD intoxication the survival rate is higher in physostigmine treated rats. Especially after relatively low doses of TAD the lethality seems to be reduced by physostigmine treatment. However, at the end of the observation period (96 h) the lethality after TAD is equal with and without physostigmine treatment. The effectivity of physostigmine does not depend on the mode of administration: repeated administration and intravenous infusion are not more effective than a single injection of physostigmine. The influence of TAD on heart rate and respiratory rate was not abolished by physostigmine salicylate. Intoxications with high doses of physostigmine were antagonized by atropine; on the other hand there are no signs for an antagonistic effect of desipramine against physostigmine intoxication, that means their anticipated anticholinergic properties could not be proved. PMID- 6927650 TI - NAD+ and NADH in brain cortex from mice exposed to high oxygen pressure. AB - Experiments were done in vivo to determine the effect of oxygen at high pressure (OHP) on NAD+ and NADH in mouse brain cortex. A 7% decrease (N.S.) in NADH was found in brain cortex from mice exposed to 6 atm of 100% oxygen for 8 min, while a 20% decrease (P less than 0.01) in cortical NADH, when compared to controls, occurred when mice were exposed to this oxygen pressure for either 16 min or 48 min. A 20% decrease (P less than 0.05) in cortical NADH was also observed in mice which had been killed during hyperactivity (a state preceding convulsions), at seizure onset, or 10 s post-convulsions. No measurable change in cortical NAD+ was observed at any of these oxygen exposure times or stages of toxicity. When mice were exposed to either 3.5 atm or 6 atm of oxygen for 16 min, a statistically significant decrease in cortical NADH (P less than 0.01) coupled with an increase in the NAD+/NADH ratio was found only at 3.5 atm and 6 atm, and not at 1 atm. The decrease in cortical NADH and increase in the NAD+/NADH ratio were reversed when mice were decompressed and exposed to air for 30 min. Disulfiram, a drug found to delay the onset of oxygen seizures, did not prevent the oxygen-induced decrease in cerebral NADH or increase in the NAD+/NADH ratio. The decrease in cortical NADH in mice exposed to OHP did not correlate with the onset of oxygen-induced convulsions. PMID- 6927653 TI - Sensory preference and overselective responding in autistic children. AB - Five autistic and five normal children were allowed to register a sensory modality preference by bar pressing to select either a visual (slides) or an auditory (music) stimulus. The children were then taught a discrimination between the presence or absence of a compound auditory-visual stimulus (white noise and light). Testing for stimulus overselectivity revealed that the autistic children attended to only one aspect of the compound stimulus. In all cases this was the sensory modality that was selected during the preference test. Significant correlations were obtained between Gesell developmental scores and degree of overselectivity. Normal children registered an equal preference for music and slides and displayed no overselectivity. PMID- 6927652 TI - A chronic study of praziquantel in Syrian golden hamsters and Sprague-Dawley rats. AB - Groups of Syrian golden hamsters and Sprague-Dawley rats received 100 mg or 250 mg praziquantel/kg body weight, intragastrically by oral gavage once weekly for 80 weeks and 104 weeks, respectively. In both hamsters and rats the observed differences in tumour incidence, latency and multiplicity revealed no positive dose response effect. Tumours observed corresponded in their origin and morphology to those which develop spontaneously in these species. Haematological and clinico-chemical values were normal. Whereas the average survival time was slightly shortened in rats, female hamsters showed reduced weight gains in the high dose level groups, although water intake and food consumption were increased. PMID- 6927655 TI - Minor physical anomalies in childhood autism. Part II. Their relationship to maternal age. AB - A group of autistic children have been found to have an excess of minor physical anomalies (MPA) and birth and pregnancy complications. However, there was not a significant positive correlation between the birth and pregnancy complications and the MPA. The relationship between MPA and maternal age in these autistic children was investigated. In the 45 autistic children studied, there was a significant positive correlation between MPA and maternal age at birth. The significance of the relationship between MPA and maternal age deserves further study. PMID- 6927654 TI - Minor physical anomalies in childhood autism. Part I. Their relationship to pre- and perinatal complications. AB - In a study of minor physical anomalies and pregnancy complications in autistic children, 45 probands and 52 of their siblings were investigated. While there was a significant association between autism on one hand and minor physical anomalies and pregnancy complications on the other, no such association was found between physical anomalies and pregnancy and birth complications. Further, autistic children with higher anomaly scores had lower IQs, more frequent hospitalizations, and a more normal family history compared to autistic children with lower physical anomaly scores. PMID- 6927657 TI - Extra prompts versus no extra prompts in self-care training of autistic children and adolescents. AB - A color-coded "extra prompt" procedure was compared to a "no extra prompt" procedure in teaching autistic children and adolescents how to lace shoes. One randomly assigned group of 10 autistic subjects first learned to lace shoes whose laces and eyelets were color-coded red and white, and then encountered the no extra prompt condition in which color codes could no longer be depended upon to solve the position discriminations required to lace properly. In a counterbalanced fashion, the other group of 10 autistic subjects reached criterion on the non-color-coded, naturalistic shoe before experiencing the extra prompt condition. Analysis of variance and post-hoc analyses suggest that subjects who first learned under the color-coded, extra prompt condition encountered significant difficulty in transferring their newly acquired skill to the naturalistic, non-color-coded condition, whereas subjects who learned initially without the extra prompts had little difficulty with the subsequent color-coded condition. A follow-up procedure requiring all subjects to choose between the color prompt and the position cue revealed that 11 of 20 subjects consistently chose the color cue, even though it resulted in improper lacing. It is recommended that clinicians avoid the use of highly salient, non-criterion related prompts in teaching certain types of adaptive skills to autistic children. PMID- 6927656 TI - Maternal age and infantile autism. AB - In a total population survey of childhood psychosis in the region of Goteborg, 20 children (2 in every 10,000) fulfilled the diagnostic criteria for infantile autism formulated by Rutter. There was a male preponderance with 15 boys and 5 girls. Eighty-five percent of the mothers were older than average. Mean maternal age in the autistic sample was 30.7 years, compared with 26.0 years in the general population. The difference is statistically significant at the .1% level. There was a strong tendency toward increasing risk of autism in the child with increasing maternal age. The fathers too were much older than average. PMID- 6927658 TI - Generalization from school to home with autistic children. AB - This investigation assessed the generalization of verbal behavior from school to home with three autistic boys. The study attempted to expand upon previous research by Handleman (1979) by analyzing the effects of single versus multiple trainers on generalization. By the use of a multiple-baseline design counterbalanced for treatment condition, the three youngsters were taught responses to common questions in two school settings and were probed to determine transfer of learning to their homes. All three children demonstrated greater generalization when they received training at varied locations as opposed to instruction in a single setting. Results of the study suggest that manipulating the school environment to more closely simulate home conditions may facilitate transfer of treatment gains to the natural setting. PMID- 6927659 TI - Treatment of assaultive hair pulling in a multihandicapped youth. AB - The course of treatment for hair pulling in a moderately retarded, visually impaired 9-year-old male is described along with the effectiveness of an ammonia inhalation procedure to eliminate this behavior. However, before discovering this successful procedure, other well-known techniques such as DRO, TO, overcorrection, and shaping all failed. Since rapid treatment effectiveness could be assumed to be the norm, given the operant literature, the extensive course of treatment reported here serves to document that perseverance may also be a necessary component of successful behavior management strategies. PMID- 6927660 TI - The Behavior Observation Scale for autism (BOS): initial results of factor analysis. PMID- 6927661 TI - Differential autonomic responses of autistic and normal children. AB - The autonomic responses of 10 autistic and 10 normal children were compared using auditory stimuli varying in social relevance. Consistent differences in heart rate response and skin conductance level were found between the groups. The results suggest that the autistic subjects exhibited deficits in psychophysiological reactivity to a range of environmental stimuli. Findings are discussed in terms of the information-processing capabilities of autistic children, and probable physiological correlates. Implications for treatment are considered. PMID- 6927663 TI - 40-43-nm viruslike particles associated with gastroenteritis. AB - By electron microscopy, 40-43-nm spherical viruslike particles were demonstrated in stools from gastroenteritis patients. The particles have 6-7-nm projections on the periphery and some of them show ringlike structures on their surface. Immune electron microscopy on paired sera and feces from one of the patients demonstrated preexisting antibody to the particles in acute-phase serum and an increase in antibody during illness. PMID- 6927664 TI - Intermittent claudication and muscle fiber fine structure: morphometric data on mitochondrial volumes. AB - The mitochondrial volume densities (Vmit) of the different fiber types (type 1, type 2A, type 2B) were estimated in bilaterally obtained biopsies from 22 patients with unilateral intermittent claudication. These data, which were obtained from structurally intact fibers, were compared with clinical data from the same subject. In both the asymptomatic and symptomatic legs, Vmit 1 greater than Vmit 2A greater than Vmit 2B. Furthermore, Vmit 1 covariated with Vmit 2A and Vmit 2A with Vmit 2B in the asymptomatic legs (as in healthy subjects) but not in the symptomatic legs. Vmit 2 (mainly Vmit 2A) covariated with the age of the subjects in both legs. Vmit Tot was higher in the symptomatic legs than in the asymptomatic legs. This was mainly due to increase in the oxidative fibers, type 1 and type 2A. Usually, Vmit in the asymptomatic legs covariated significantly with the results of the functional tests (initial pain and maximum walking tolerance), while only Vmit 2A in the symptomatic legs showed such a correlation. However, the difference between the two legs concerning Vmit 1 was also correlated to the walking tolerance. Patients with high stenosis or occlusion showed higher Vmit Tot than did those with low obstacles. The results conclusively show that a fiber type-specific adaptation to ischemia occurs through an increase of mitochondrial content of oxidative fibers, which suggests that hypoxia may influence the control of synthesis or degradation of mitochondrial proteins. PMID- 6927662 TI - Emotional disturbance in mental retardation: an investigation of differential diagnosis. AB - The study sought to determine whether 100 emotionally disturbed mentally retarded subjects assigned four distinct diagnostic labels could be differentiated from each other on the basis of sex, age, degree of mental impairment, and adaptive behavior. Univariate and multivariate analyses indicated that the autism classification was distinguishable from psychosis, schizophrenia, and severe emotional disturbance in terms of degree of retardation and adaptive behavior. The primary distinguishing feature was the autistic group's low level of language development. The schizophrenics, psychotics, and severely emotionally disturbed subjects were indistinguishable from each other on the variables examined. PMID- 6927665 TI - Analysis of a polytef granuloma mimicking a cold thyroid nodule 17 months after laryngeal injection. AB - A 65-year-old female who received laryngeal injections with polytef (Teflon) paste for treatment of right vocal cord paralysis first noticed a small, right anterior neck mass 17 months later. Clinically this mass slowly progressed in size and was felt to be a recurrent carotid body tumor, but at surgery, 22 months after injection, a circumscribed nodule on the anterior right lobe of the thyroid was found and histologically diagnosed as a foreign body granuloma. Scanning electron microscopy (SEM) and energy-dispersive x-ray analysis (EDXA) of material in this lesion was identical to that of polytef paste, which is a mixture of pyrolyzed polytetrafluoroethylene and glycerine. The possibility that deaggregated smaller particles in the polytef paste were able to migrate from the injection site resulting in this neck mass is considered. PMID- 6927667 TI - Nasal blastoma: a light and electron microscopic study. AB - The first light and electron microscopic study of a nasal blastoma is reported. Analogous to a pulmonary blastoma, the tumor is composed of well-differentiated squamous and glandular epithelial elements surrounded by a spindle cell stroma. The spindle stromal cell is a myofibroblast. Eighteen months after complete surgical removal of the tumor and radiation therapy, the patient is clinically free of disease. PMID- 6927668 TI - Microtubular aggregates in the rough endoplasmic reticulum of a myxoid chondrosarcoma. AB - A tumor with the light microscopic and histochemical characteristics of myxoid chondrosarcoma is examined ultrastructurally. Instead of the usual features of chondroblasts, the tumor cells exhibited prominent collections of long straight microtubules within the endoplasmic reticulum. This finding is compared with other previously reported tubular aggregates. The differential diagnosis and ultrastructure of myxoid chondrosarcoma are also discussed. PMID- 6927666 TI - Intracytoplasmic lumina with and without cilia in both normal and pathologically altered nasal mucosa. AB - Two different types of intracytoplasmic lumina have been observed electron microscopically in pseudostratified and metaplastic human nasal mucosa: one type contains microvilli and the other contains both microvilli and cilia. The latter type was seen only in pseudostratified columnar epithelium, while the former was also observed in different stages of metaplasia. From these observations we conclude that the type of intracytoplasmic lumina is determined by the differential potential of the cells in which they occur. Serial sectioning demonstrated that these structures sometimes communicate with the extracellular space. The distinctly different ultrastructure of microvilli lining the intracytoplasmic lumina and the foldlike extensions of the cell membrane favors an intracellular genesis rather than a formation by invagination of the cell membrane. It is suggested that intracytoplasmic lumina occur as a consequence of dysregulation in the process of epithelial maturation. PMID- 6927669 TI - Electron microscopic and immunohistochemical analysis of glomerular deposits in patients with bronchogenic carcinoma. AB - Kidneys of 27 consecutive autopsied patients with bronchogenic carcinoma without clinical renal disease were studied by electron microscopy and immunohistochemistry for the presence of glomerular deposits. Two patients had subepithelial electron-dense deposits compatible with immune complexes but failed to stain histochemically for immunoglobulin; most cases (19 of 27), including the two with complexes, demonstrated subendothelial deposition of fibrin. No tissue samples had histochemically detectable immunoglobulin. From this study it is suggested that renal immune complexes in lung cancer are rare. PMID- 6927673 TI - Guidelines for the production and implementation of public service announcements for television. Part I. PMID- 6927674 TI - A systematic approach to medical motion picture production. Part IV. PMID- 6927671 TI - Adaptation of a thirty-five millimeter photographic system for a scanning electron microscope. PMID- 6927675 TI - Critical color rendition in hematopathology. PMID- 6927670 TI - The quarterly case: nephrotic syndrome in a middle-aged man. PMID- 6927676 TI - A simultaneous treatment comparison of three expressive language training programs with a mute autistic child. AB - A study was conducted in order to simultaneously compare the relative effectiveness of three different language training models (total communication sign training, nonverbal "sign-alone" training, and oral [vocal] training) for teaching expressive language skills to a 4 1/2-year-old mute autistic child. A single-subject, alternating-treatment (multielement) design with replication within subject was used to compare the rate of expressive word acquisition across training models. Results show the total communication model to be substantially superior to both oral and sign-alone training models, and place in question the theory of an intersensory integration disability to explain the success of sign language. Alternatively, the data suggest that the use of physical prompts combined with multisensory inputs provide a basis for the demonstrated success. PMID- 6927677 TI - Cross-sectional studies of grammatical morphemes in autistic and mentally retarded children. AB - The frequency of occurrence of functors in obligatory contexts was studied in verbal autistic and mentally retarded children matched for nonverbal mental age, and the percentages of correct use of functors were rank-ordered. The grammatical complexity of their language was also described using a transformational grammar. The data were compared to those obtained in a normal group matched for mental age and to the data presented by Brown (1973) and deVilliers and deVilliers (1973) in younger children. The autistic subjects omitted functors frequently and independently of the grammatical complexity of their language. The rank ordering of morphemes was consistent within both the autistic and mentally retarded groups but showed no correlation between the two groups or to the rank ordering described by deVilliers and deVilliers. It is suggested that functors in autistic subjects may develop in an atypical but consistent order and that this may be due to specific semantic deficits, particularly in the areas of person and time deixis. PMID- 6927678 TI - The responsiveness of autistic children to the predictability of social and nonsocial toys. AB - This study was designed to explore autistic children's ability to develop an expectancy from environmental events. Social and nonsocial toys were presented to autistic and control children in situations that either allowed or prevented them from predicting their appearance. It was found that autistic children's behavior was seriously disrupted if they could not predict the sequence of environmental stimuli, but their responsiveness to environmental stimuli increased when events were predictable. They approached social objects more readily than nonsocial objects when both were simple in appearance. These findings suggest that an appropriate starting point for therapeutic intervention with autistic children might be to focus on shaping social play in highly structured and predictable environments. PMID- 6927679 TI - Ecological assessment of self-protective devices in three profoundly retarded adults. AB - Three profoundly retarded adults were observed in an experimental daycare program when they were not wearing self-protective restraints and when they were wearing them to prevent pica and rectal digging. The noncontingently applied devices did eliminate the target behaviors, but they also decreased social interactions between the subjects and their caretakers. A camisole was found to be even more restrictive than a fencing mask. PMID- 6927672 TI - Adding selected areas of color to black and white slides by color coupling. PMID- 6927680 TI - Treatment of atypical anorexia nervosa in the public school: an autistic girl. AB - Because of the increase in public school programs for severely handicapped children, teachers are more likely than ever to be confronted with serious medical or psychological problems like anorexia nervosa. In this case study, desensitization successfully treated the eating disorder of a preadolescent autistic girl. However, the case also accentuated the problems teachers face in making appropriate decisions due to conflicting literature findings, traditional role responsibilities, and lack of expert resources and supportive services in the public school settings. If programs are to meet the needs of these children in the future, service and resource models for the public school settings must be developed. PMID- 6927681 TI - A self-control classroom for hyperactive children. AB - In this study we investigated the effectiveness of a package of self-control procedures in a classroom with six hyperactive boys ages 7 to 10. A within subjects reversal design was used. Measures of on-task behavior and class misbehavior, as well as measures of activity level, were recorded. Results indicated that the self-control package was effective in improving misbehavior and attention to tasks during the individual seat work but not during group instruction. Activity level was not affected by the treatment. Changes in the schedule of self-monitoring for the boys in the class produced an increase in variability and some deterioration in their behavior. Those boys of lower mental age seemed most affected by the schedule shift. PMID- 6927682 TI - Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS). PMID- 6927683 TI - Training and generalization of yes and no as mands in two autistic children. AB - This study presented a practical and replicable procedure to train and generalize the use of "yes" and "no" as mands by a nonverbal boy and a previously echolalic girl, both diagnosed as autistic. The procedure used systematic modeling and reinforcement with detailed criterion for introducing and terminating the training stimuli. The subjects were first trained to use yes and no to mand three food items, following the stimulus question "Do you want...?" and presentation of a food item. The teachers then tested the subjects for generalization of the two mands to successive sets of new food items. The results showed that the nonverbal subject needed to be trained on five sets of food items before generalization occurred. The previously echolalic subject generalized and maintained the two mands after being trained on only one set of items. The study thus demonstrated that the procedure was effective in training two useful mands for the autistic children, and that after such training, the behavior may then generalize to new items without training. Specific response patterns and the importance of intermittent modeling and arrangement of reinforcers in the training are discussed. PMID- 6927684 TI - Blind evaluation of body reflexes and motor skills in learning disability. AB - Motor dysfunctions have been associated with learning disabilities in casual observation and systematic study. However, most prior work has concentrated solely on high-level skills and has been subject to observer bias. In this study, boys with learning disability were blindly compared with paired controls on measures of postural and equilibrium reflexes as well as skills. Learning disabled children as a group showed significant deficits on all measures; a few, however, were totally without deficit. The implications of these findings for controversies about the role of motor dysfunction in learning disabilities are examined. PMID- 6927686 TI - Acute onset of autistic features following brain damage in a ten-year-old. AB - We report the case of a 10-year-old boy who, following a prolonged period of unconsciousness, displayed severe eye-to-eye gaze avoidance, sensory inattention, and some other behavioral symptoms normally associated with the syndrome of infantile autism. The symptoms lasted only a few months and were associated with the more permanent behavioral changes of postencephalitic psychosis. Serial computerized tomography scans were taken during his illness and recovery. The relevance of this case to the etiology of infantile autism is discussed. PMID- 6927687 TI - Treatment of aggressive behavior: the effect of EMG response discrimination biofeedback training. AB - This N of 1 study utilizes a withdrawal design with aggressive responses of a 27 year-old male exhibiting autistic behavior. The frequency of physical and verbal aggressive responses was decreased by reinforcing attempts to relax (utilizing EMG biofeedback) when discriminative stimuli for aggressive behavior were present. PMID- 6927685 TI - Effects of age on adaptive behavior levels and academic skill levels in autistic and mentally retarded children. AB - This study investigated the effect of age on adaptive behavior and academic skill in autistic and mentally retarded children. Subjects were 47 autistic and 128 mentally retarded children from a special school. Cross-sectional comparisons were made between junior and senior groups using ratings obtained from teachers on adaptive behaviors and academic skills. We found that the levels of toilet training, eating skills, participation in group activities, and self-control in the autistic children improved significantly with age. The skills of number concepts in the autistic children also improved with age. However, these adaptive and academic levels were in general significantly lower than those of the mentally retarded children. The levels of initiative did not improve significantly in either the autistic or the mentally retarded children, and they were significantly lower in the autistic children. The implications of these findings in the context of our previous study on the changes of communication and maladaptive behaviors with age in the autistic children are discussed. PMID- 6927688 TI - Auditory brainstem evoked responses in autistic children. AB - Previous studies have implicated a brainstem dysfunction in the syndrome of autism. This study matched six autistic children with six normal children by age and sex to evaluate brainstem evoked response (BSER) to auditory stimuli. An evaluation of pure tone audiometric threshold showed no evidence of impairment; however, the electrophysiologic responses differed for the autistic and control groups. The BSER of the autistic children was remarkable for showing increased latency and markedly increased variability. The findings from this study add additional evidence of a brainstem dysfunction in autistic children, while the electrophysiologic variability supports the hypothesis of perceptual inconstancy. PMID- 6927689 TI - Gorky's "Nilushka": autism case report? PMID- 6927690 TI - Why do autistic children...? PMID- 6927691 TI - Critical comments on "Teaching autistic children to use sign language: some research issues". PMID- 6927692 TI - Some perspectives on intervention strategies for persons with developmental disorders. AB - We present a view of language that crosses modal considerations (e.g., speech vs. augmentative systems) and places language within an interaction framework. We emphasize the need to consider normal social, cognitive, and linguistic development in selecting program guidelines for developmentally delayed persons. We address the child's linguistic code not as a set of phonetic, syntactic, and semantic features that can be trained in isolation, but as a means by which he can exercise the various pragmatic uses of communication. In effect, our interest has thus expanded from the child alone to the child as one member of a communicating dyad. Programming in the areas of mother's verbal input, expanding children's language skills, training in augmentative systems--all reflect an overriding objective of optimizing the language-user's ability to successfully participate in interactions with other persons in his/her environment. PMID- 6927695 TI - Dissociations between language and cognition: cases and implications. AB - An important issue for the cognitive sciences is whether grammar is to any nontrivial extent an autonomous cognitive system. Current cognitive hypotheses of language acquisition would argue against an autonomous linguistic system and would support the notion that language emerges from more general cognitive knowledge and is throughout its development fundamentally tied to a nonlinguistic cognitive base. This paper explores this issue and presents data from case studies of children showing clear dissociations between language and nonlanguage cognitive abilities. The implications of such data are discussed. The major implications appear to be that lexical and relational semantic abilities are deeply linked to broader conceptual development but morphological and syntactic abilities are not. The development of a normal linguistic system, however, one in which grammar is systematically related to meaning, requires concurrent and concomitant linguistic and nonlingustic cognitive development. PMID- 6927693 TI - Sign language and autism. AB - Research findings and issues in teaching sign language to nonspeaking autistic children are reviewed. Data on over 100 children indicate that nearly all autistic children learn receptive and expressive signs, and many learn to combine signs. These children also exhibit marked improvement in adaptive behaviors. Speech skills are acquired by fewer children and may be developed through simultaneous speech and sign training. Possible explanations for these results are given, together with suggestions for future research and data collection. Recommended innovations include exposure to fluent signers and training in discourse and code-switching. Different sign language teaching methods need to be investigated more fully, including emphasis on training sign language within the children's total environment and with greater staff and parental participation. PMID- 6927694 TI - A strategy for research on the use of nonvocal systems of communication. AB - This paper discusses problems with current research on the use of nonvocal communication systems with special reference to the severely and profoundly mentally retarded. A strategy for research, designed to provide a method whereby critical practical and theoretical issues can be isolated, is described. The approach involves surveys of use, development of procedures for assessment and program monitoring, the development of teaching methods for use with neglected groups, and experimental investigations of the interaction of system variables and subject characteristics. The strategy is illustrated with examples from ongoing research. PMID- 6927696 TI - Issues in the modification of American sign language for instructional purposes. AB - The use of manual communication and sign languages for language education of autistic, deaf retarded, and mentally retarded individuals is receiving increasing attention by educators. Modifications of sign systems for this purpose emphasize simplicity, redundancy, and English word order. Effective utilization of manual communication for these populations requires a better understanding of the physical and linguistic bases of sign languages than now exists. Preliminary evidence from studies of oral-only, manual-only, and oral-manual modes of communication suggests that flexibility in utilizing all modes is the most effective teaching method. The present paper will consider the possible utilization of modifications of the American Sign Language for use in three general areas: instruction of deaf students in the classroom, communication between hearing parents and young deaf children, and communication with individuals with handicaps other than deafness. PMID- 6927697 TI - Language, social, and cognitive impairments in autism and severe mental retardation. AB - An epidemiological study is outlined that shows that Kanner's syndrome is one group among a wider range of children, all with impairment of social interaction, communication, and imagination. Most, but not all, children with this triad of impairments are severely mentally retarded, although severe retardation also occurs in those who are sociable and communicative. It is hypothesized that the socially impaired lack certain abilities that are inborn in normal children and the sociable mentally retarded: namely, the capacity to produce and monitor the normal species-specific preverbal sounds, the drive to explore the environment and form concepts to explain experiences, and the ability to recognize that other human beings are of special interest and importance. A possible neurological basis for these problems is briefly considered. PMID- 6927698 TI - On the nature of linguistic functioning in early infantile autism. AB - This paper provides a review of studies conducted on linguistic functioning in autistic children, within the framework developed in normal language acquisition research. Despite certain methodological weaknesses, the research consistently shows that phonological and syntactic development follow the same course as in normal children and in other disordered groups, though at a slowed rate, while semantic and pragmatic functioning may be specially deficient in autism. These findings are related to other recent studies on the relative independence of different aspects of language. PMID- 6927699 TI - Developmental language disorders: cognitive processes, semantics, pragmatics, phonology, and syntax. AB - Five areas of research concerned with language acquisition--cognitive processes, semantics, pragmatics, phonology, and syntax--are reviewed in terms of their contribution to understanding language disorders. Two views of cognitive processes are discussed. One of these, emphasizing cognitive mechanisms such as short-term memory, is seen as providing possible explanations for some types of language deficits. The other, a concern with conceptual knowledge, is subjected to a critical analysis questioning how complete an explanation it is able to offer for some aspects of language acquisition. Problems of definition are also discussed when semantic aspects of language are considered. Problems in the pragmatic component of language are seen as providing an explanation for particular aspects of language disorder in some autistic children. The importance of focusing on phonology as a central grammatical process is discussed and linked to dyslexia and to spelling disorders. Finally, it is argued that the acquisition of syntactic structure is not yet understood. Impairments such as a hierarchical planning order deficit may affect syntactic ability and lead to disordered language, as found in some types of developmentally aphasic children. It is concluded that it is important to study all five areas of the title, and their interrelationships, if various language disorders are to be adequately understood. PMID- 6927700 TI - Linguistic pragmatics and language intervention strategies. AB - The recent research focus on pragmatics leads to the consideration of issues of language use that have fundamental practical implications for language assessment and intervention. Specifically, the pragmatic orientation suggests changes in the content of language assessments, by evaluating various communicative functions the child expresses, and modifications in the process of language assessment, by encouraging both the initiating and responding dimensions of the child's communicative behavior. Furthermore, the pragmatic focus suggests changes in the process of intervention. The primary goal of intervention becomes facilitation of generalized communicative functions for which syntactic structures and semantic content are only the tools. And the pragmatic framework suggests guidelines for what constitute appropriate reinforcers that sustain rather than interrupt communicative interactions. PMID- 6927701 TI - The effectiveness of operant language training with autistic children. AB - Studies of operant language therapy with autistic children have indicated that behavioral techniques may be of value in increasing the language skills of such children. A review of recent studies, however, suggests that in the absence of adequate experimental controls, misleading conclusions may be drawn about the effectiveness of treatment. It is also apparent that the effects of therapy vary according to the linguistic competence of the children involved, and to the different aspects of language ability being taught. The implications of recent findings for our understanding of the basic deficit underlying early childhood autism are discussed. PMID- 6927703 TI - Comparison of auditory stimulus processing in normal and autistic adolescents. AB - This experiment investigated the possibility that autistic adolescents may avoid speech communication with the world around them by "tuning out" or perceptually suppressing auditory speech stimuli. The tune-out auditory suppression hypothesis was investigated using the subject's own speech as the stimulus under three perceptual-motor conditions: with speech in a delayed auditory feedback (DAF) mode, with a white noise masking speech mode, and with speech in a normal, quiet listening mode. Five autistic adolescents were compared with six normal controls on speech time duration and sound level. DAF increased the speech sound pressure level (SPL) and increased speech time duration for both groups. PMID- 6927706 TI - Parameters of the meal pattern in rats: their assessment and physiological significance. AB - Parameters of the meal pattern in rats were assessed and their physiological significance investigated through a detailed study of continuous graphic recordings over 20 consecutive days in ten rats. Both prandial and diurnal periodicities were examined. The definition of meals, by a criterion of 40 min of non-eating before and after a feeding episode, was validated statistically. The two superimposed periodicities were substantiated by studying night and daytime differences in meal sizes, meal-to-meal intervals, meal size/interval ratios, and post prandial correlations. The results provide new evidence for the role of metabolic and neuroendocrine factors in determining the relationships between meal size and post-meal intervals and their differences during the two parts of the diurnal cycle. PMID- 6927704 TI - Some findings on the use of the adaptive behavior scale with autistic children. AB - Two studies on the use of the AAMD Adaptive Behavior Scale (ABS) with autistic children are reported. The first study compared ratings by parents and teachers on the same child. For Part I (Adaptive), significant correlations were found on total score and on 7 out of 10 individual scales. For Part II (Behavior), significant correlations were found on only 3 out of 14 scales and not on total score. The second study examined change measured by the ABS across an academic year. For Part I, significant change occurred on 5 of the 10 scales and on total score; for Part II significant differences were found on 2 of the 14 scales and not on total score. Correlations with IQ, Social Quotient (SQ), and degree of autism revealed a similar pattern. The implications of the differences between the two parts of the ABS and their utility for autistic children are discussed. PMID- 6927702 TI - Implication of sex differences in the familial transmission of infantile autism. AB - There are studies suggesting possible hereditary influence in autism. Data on 102 autistic children, 78 boys and 24 girls, showed that there was a significantly greater proportion of autistic girls than boys with IQs less than 50 and with evidence of brain damage. The autistic girls also had a greater proportion of relatives affected with autism or cognitive-language deficit than did the boys. The implication of sex differences in the possible mode of familial transmission of autism is discussed. PMID- 6927705 TI - Autistic children's responses to structure and to interpersonal demands. AB - Ten autistic children were exposed to four different styles of approach by an adult, in which the common context was the child's involvement in the completion of a model-building task. These styles varied in the extent to which they made interpersonal demands of the child and in the amount of task-directed structure that was imposed. Measures based upon observation of the adult's and the children's behavior indicated that the styles applied were reliably discriminable, and that the children's responses, both social and task-directed, were positively related to the interpersonal and task-oriented demands that were made of them. Within the group of children tested, some individual differences in the responses to the styles were suggested that may be relevant to the diagnosis of autism. PMID- 6927707 TI - Body energy regulation and the stimulation to eat. PMID- 6927708 TI - Food deprivation induced parallel changes in blood glucose, plasma free fatty acids and feeding during two parts of the diurnal cycle in rats. AB - The changes in plasma glucose and free fatty acid levels and in subsequent feeding induced by 4 to 10 hr of food deprivation were investigated in rats and compared for the two parts of the diurnal cycle. It was found that increasing fast duration at night induced a more rapid fall of plasma glucose and elevation of plasma free fatty acids than in the day. However, a similar increment of the first post fast meal was elicited by an identical decrement of blood glucose level for the two periods except after a 10 hr fast during the day. The acute effect of darkness and light per se being experimentally excluded, it was concluded that the size of the first meal following short term food deprivation was dependent throughout the diurnal cycle on the fast induced glucoprivic condition. PMID- 6927710 TI - Variations of meal-to-meal liver glycogen in rats. AB - Liver glycogen content was determined in free feeding rats sacrificed at the beginning of nocturnal meals or 60 min later. It was found that the glycogen content at the beginning of meals and 60 min later was highly correlated with the cumulative food intake since the beginning of the dark cycle, and therefore, increased from meal to meal. The comparison of these correlations between the cumulative food intake and the liver glycogen at the beginning of the meal and 60 min after ruled out the possibility that a constant decrement of glycogen might be involved in both meal onset and prandial periodicity of feeding. Rather the results are consistent with the view that the glycogen load during the night is a minute carbohydrate store which, like the fat store, is involved in the diurnal 12/12 hr feeding periodicity. PMID- 6927709 TI - Changes of meal patterns induced by food deprivation: metabolic correlates. AB - Six hour food intake following 0 to 6 hours of food deprivation was compared during the light and dark cycle in rats. Changes in the size of the first meal and the length of the first post-meal interval, as a function of deprivation, were related to plasma glucose and free fatty acid levels immediately prior to and 90 minutes following the first meal. It was determined that at night the size of the first meal increased and the relative duration of the post-meal interval decreased as a function of previous fast duration. The shortening of post-meal satiety was associated with the food deprivation induced decrease of blood glucose level and rise of free fatty acids which were observed prior to the meal. The fast induced changes of the meal pattern observed at night and the resulting 6 hour hyperphagia support the conclusion that the duration of post-meal satiety is determined by the meal-to-meal balance between energy intake and utilization. PMID- 6927711 TI - Differential effects of 2-deoxy-D-glucose on plasma glucose, free fatty acids and feeding during the light and dark cycle in rats. AB - The effects of 2-deoxy-D-glucose (2-DG) combined with 0 to 6 hr of food deprivation on plasma glucose (PG), plasma free fatty acid (PFFA) levels and feeding were compared during the 2 parts of the diurnal cycle. In one group, PG and PFFA were measured prior to the injection of either 2-DG or saline and 90 min after injections without restoration of access to food. In a second group, food was reintroduced following injection and intake was measured. At night, PG and PFFA measured prior to injections decreased and increased with respect to the length of food deprivation. Ninety minutes after 2-DG, PG and PFFA were elevated above control levels as a function of previous deprivation. During the day, fasting time did not affect PG and PFFA 90 min after a saline injection; but, after 2-DG, PG increased and PFFA decreased irrespective of the previous deprivation period. At night, food intake increased after saline and 2-DG as a function of fast duration, but increases were significantly lower after 2-DG. During the day, the duration of food deprivation did not affect food intake after 2-DG and saline; but irrespective of previous food deprivation, the cumulative intake of the first 2 hr was higher after 2-DG. Results are discussed in relation to the dual activation by 2-DG of facilitatory and inhibitory mechanisms of food intake. PMID- 6927712 TI - Recovery of body weight following starvation or food restriction in rats. AB - Recovery of body weight and food intake have been studied and compared after a 25% weight loss produced by total starvation in one group of rats or by food restriction in a second group. It was shown that rats in both groups returned to their initial body weight within the same time on the average, but the hyperphagia observed during the recovery phase was significantly higher in restricted than in starved rats. In the former, the increase of food intake fully accounted for the weight gain. On the contrary, the recovery of body weight in previously starved rats involved both hyperphagia and a long lasting persistence of the fasting hypometabolism. In addition, it was shown that in those rats the higher the contribution of hypometabolism the longer the recovery. Starvation diabetes was higher in starved than in restricted rats and might be one factor which impairs weight regulation through hyperphagia after a weight loss induced by food deprivation. PMID- 6927713 TI - Risk management: an analysis of technologist liability. AB - Should radiologic technologists be concerned about the risk they may or may not have in being named as a defendant in a medical negligence suit? The risk is analyzed in terms of possibility and probability of suit. Suggestions are made concerning the management of that risk in the light of court decisions, trial tactics, and legal doctrines. PMID- 6927714 TI - Simplified radiography of the zygomatic arches (the rat's head view). AB - Using these projections, the radiographer can effectively demonstrate depressed fractures or pathology of the zygomatic arches. Proper use of magnification techniques allows maximum detail without distortion for simplified viewing. PMID- 6927715 TI - Mattress for treatment couch. AB - A thin vinyl foam pad is described for use with radiation therapy treatment couches. This pad provides for adequate patient comfort while supplying a sufficiently firm support as to permit good patient immobilization. PMID- 6927716 TI - Articulation: an imperative to effective instruction. PMID- 6927717 TI - Coronary care units today--Part II. PMID- 6927718 TI - Bacteremia in diabetic patients with infected lower extremities. AB - Eleven cases of bacteremia in diabetic patients with infected lower extremities at Rancho Los Amigos Hospital (RLAH) were observed over a 34-mo period. The yearly incidence was 0.6% of admissions to the Ortho-Diabetes service. Aerobic bacteria were recovered in six cases and anaerobic bacteria in five. Bacteroides fragilis was isolated four times, Staphylococcus aureus three times, and nonfragilis Bacteroides sp., Escherichia coli, group B streptococcus, and viridans streptococcus were each seen once. Ten of the 11 patients were febrile at the time of bacteremia. Clinical, laboratory, radiologic, and ultrasonographic parameters were comparable in patients with aerobic and anaerobic bacteremia, and between bacteremic patients and nonbacteremic controls. Fever, however, was significantly more frequent in bacteremic patients. Foul-smelling lesions were seen in two of the five patients with anaerobic bacteremia, and in none of the patients with aerobic bacteremia. Postoperative B. fragilis bacteremia was observed to be transient and resolved without definitive therapy in one patient. Appropriate antibiotic therapy in 10 patients together with surgical intervention in eight cases resulted in resolution of the infection in the remaining patients. PMID- 6927719 TI - Causes of errors in diabetic urine testing by hospital personnel. AB - Errors in urine testing were studied using 119 health professionals who tested simulated urine specimens from six hypothetical patients. A record of the hypothetical patients' test results for 2 previous days accompanied each specimen. Five of the six records were loaded high or low to investigate testers' biases as a result of their knowledge of previous values. Testers demonstrated an aversion to extreme readings. At the lower concentration, 83% of erroneous readings were higher than the correct value. At the higher concentration, 70% of errors were below the true value. The results also revealed that readings were influenced by knowledge of past records. A higher reading for the sample with the biased-high record occurred 50% more often than a lower reading. Differences in error were nonsignificant for different educational levels and past experiences of the testers. Urine testing accuracy appears to be affected by a tendency toward avoidance of extremes and knowledge of previous results. PMID- 6927720 TI - Diabetes in Kentucky. AB - A state diabetes commission and university diabetes program in Kentucky jointly studied the social and economic impact of diabetes mellitus and its complications on the Commonwealth. This investigation revealed that diabetes was a more serious public health problem than previously supposed. Active, diagnosed diabetes afflicts 4.4% Kentucky's population. Less severe clinical and "borderline" forms of diabetes affect an additional 2.4%. Diabetes is especially prevalent in Appalachian regions and in rural, Western Kentucky. In contrast, its prevalence in Lexington, the second-largest city, is 2.7%, similar to the current, estimated national prevalence. Diabetes is the leading cause of hospitalization by disease, and costs approximately $98,800,000 to $135,000,000. Previous estimates of these social and economic losses were lower, partly because they failed to account for the impact of diabetic complications. An average of 5.23% of all hospitalized Kentuckians have diabetes. Specific services for diabetes care, including organized patient education programs, social or psychological counseling, and preventive foot care, were offered by less than 8% of accredited Kentucky hospitals. This study demonstrates the disparity between need and available services, particularly preventive services, for diabetes care in the health care system. PMID- 6927722 TI - Indications for use of continuous insulin delivery systems and self-measurement of blood glucose. American Diabetes Association. PMID- 6927723 TI - Glycohemoglobin stability. PMID- 6927721 TI - Optimizing pumped insulin delivery. AB - The use of portable devices for the subcutaneous infusion of insulin may facilitate the attainment of improved glycemic control in selected patients with insulin-dependent diabetes mellitus. Successful use of a program of continuous subcutaneous insulin infusion requires patient cooperation and motivation, routine monitoring of glycemia, and attention to food intake and activity. This article describes an approach by which patients may optimize glycemic control utilizing a set of algorithms based on patient-determined blood glucose measurements. The algorithms permit programming the insulin infusion device to achieve the desired control. PMID- 6927724 TI - Blood glucose measurements. PMID- 6927725 TI - First-voided or second-voided urine testing? PMID- 6927726 TI - Mismanagement of infusion pumps. PMID- 6927727 TI - Effect of acarbose on the 24-hour blood glucose profile and pattern of carbohydrate absorption. AB - Acarbose (Bay g 5421) is a powerful alpha-glucoside hydrolase inhibitor of potential value in the treatment of diabetes and hypoglycemic dumping syndrome after gastric surgery. The extent of its use may be limited by symptoms produced by carbohydrate malabsorption. To minimize these, the action of low doses of acarbose on 24-h blood glucose profiles and hydrogen evolution have been studied on four ambulant volunteers on control diets, after exclusion of sucrose and also after addition of guar in an attempt to enhance the therapeutic effect. Replacement of dietary sucrose by starch abolished significant hydrogen evolution in the morning after low doses of acarbose but did not reduce its effectiveness in decreasing the mean three-meal blood glucose area by 41% (P less than 0.002). Addition of hydrated guar to this diet reduced the mean three-meal glucose area after acarbose further by 72% (P less than 0.001) but increased hydrogen evolution. The results suggest that acarbose will be both effective and acceptable given at low dose when the dietary carbohydrate is starch. PMID- 6927728 TI - Risk factors associated with severe proliferative retinopathy in insulin dependent diabetes mellitus. AB - The natural history of disease and suspected risk factors for bad prognosis were investigated in 40 subjects with insulin-dependent diabetes mellitus who had severe retinopathy and in 22 patients with a similar duration of diabetes without evidence of complications. The retinopathy group showed a marked excess of men (ratio 2:1). Examination of the data in the literature also showed a striking excess of men, 61% (P less than 0.001) in patients with insulin-dependent diabetes and severe microvascular disease. In addition, proliferative retinopathy was found to have significant associations with current poor diabetic control, hypertension, and previous treatment with once-daily insulin regimens, particularly with protamine zinc insulin. PMID- 6927729 TI - Glycosylated hemoglobin and fasting plasma glucose in the assessment of outpatient glycemic control in NIDDM. AB - Interpreting measurements of fasting plasma glucose (FPG) and glycosylated hemoglobin (GHb) is subject to inherent limitations. The time course of change in GHb cannot be reliably specified in the individual patient, nor do single measurements of GHb convey any information regarding recent change or stability in glycemic control. To evaluate whether the clinical utility of these measurements may be extended, sequential measurements of FPG and GHb were examined from 16 outpatients with NIDDM followed over periods of 12 successive weeks or longer, including intervals following cessation of prior therapy or initiation of new hypoglycemic therapy with glipizide. In some individuals as well as groups of patients, changes in GHb followed patterns previously described by mean changes among groups of patients. Differing from those patterns, however, other individuals demonstrated prompt improvement in GHb following substantial improvement in FPG, confirming that patterns of change described from group means do not apply to all circumstances of changing glycemic control, though they may represent the most common. By using measurements of both FPG and GHb obtained on a single occasion to calculate a third parameter, called the glycosylated hemoglobin index (GHb-1), accurate information could be obtained regarding changes in glycemic control which occurred over intervals of 1-4 wk prior to the measurements. By this approach the utility of GHb measurements in the management of outpatients with NIDDM may be extended beyond retrospective description of the "average" prior metabolic control to include assessment of recent changes in glycemia, either deterioration or improvement. PMID- 6927730 TI - Impaired glucose tolerance and diabetes mellitus in elderly subjects. AB - In a 10-yr prospective population study 406 subjects who were 70 yr old received an oral glucose tolerance test. Of these subjects 169 were retested at 80. Three sets of diagnostic criteria were evaluated, of which the WHO criteria are recommended for screening studies in this age group. The prevalences of diabetes mellitus (DM) and impaired glucose tolerance (IGT) according to the latter criteria were 10% and 26% at 70 and 12% and 35% at 80 in men and women. Excess 10 yr mortality was seen in both sexes when DM existed at 70, and in men also when IGT existed at this age. The excess mortality in men could solely--and in women partly--be explained by cardiovascular diseases. The 10-yr incidence of DM was 20% if IGT existed at 70, but only 4% when normal glucose tolerance was present at 70. PMID- 6927731 TI - Diet liberalization and metabolic control in type I diabetic outpatients treated by continuous subcutaneous insulin infusion. AB - In 10 type I diabetic outpatients treated by continuous subcutaneous insulin infusion (CSII), dietary habits and metabolic control were investigated. Under conditions of a conventional diabetes diet (including 5-6 meals per day and a strictly planned meal intake) as well as under a "less restricted diabetes diet" (e.g., free choice of number, timing, and amount of carbohydrate intake) near normoglycemia could be achieved. Mean daily blood glucose levels did not change significantly when the patients' nutrition was alternated between both diets. During the "less restricted diabetes diet," the patients opted for a rather high fat intake (51 +/- 5% fat, 34 +/- 5% carbohydrate, and 15 +/- 2% protein). Despite this unintended dietary behavior, serum lipids and body weight remained normal after an observation period of 4-6 mo. It is concluded that during permanent near normoglycemia achieved by CSII a partial liberalization of the diabetes diet does not introduce any short-term or long-term metabolic risk factors for cardiovascular diseases. PMID- 6927732 TI - Kidney function after improved metabolic control in newly diagnosed diabetes and in diabetic patients with nephropathy. AB - To evaluate the effect of improved metabolic control on kidney function, urinary excretion rate of beta-2-microglobulin, lysozyme, and gamma-glutamyltransferase were evaluated in nine poorly controlled, newly diagnosed diabetic patients before and during treatment. In six poorly controlled insulin-dependent nephropathic diabetic patients, besides the parameters cited above, urinary albumin excretion rate and IgG/transferrin clearance ratio were further investigated to estimate the permeability and the selectivity of glomerular barrier during conventional treatment and after improvement of the metabolic control by a glucose-controlled insulin infusion system (GCIIS). The improved glycemic control resulted in a significant reduction of urinary beta-2 microglobulin and lysozyme excretion in all diabetic patients. Significant decreases of urinary albumin excretion and of IgG/transferrin clearance ratio (indicating a more selective proteinuria) during strict metabolic control were also observed in nephropathic diabetic patients. The reduction of urinary beta-2 microglobulin and lysozyme excretion indicates that a tubular reabsorptive dysfunction, reversible with the amelioration of glycemic control, can be observed in poorly controlled, newly diagnosed and in insulin-dependent nephropathic diabetic patients during conventional treatment. In the latter patients, the permeability and the selectivity properties of glomerular barrier also improved during GCIIS. PMID- 6927733 TI - Problems with insulin syringes. PMID- 6927735 TI - Psychological issues in diabetes: a different approach. PMID- 6927734 TI - Hypoglycemic coma due to use of an improper battery in a commonly used insulin pump. PMID- 6927738 TI - Sorbitol and plasma glucose. PMID- 6927736 TI - Lipid disorders in diabetes. PMID- 6927737 TI - Dietary factors and hyperlipidemia. PMID- 6927740 TI - Dextrostix. PMID- 6927741 TI - Time-action profile of zinc human insulin (recombinant DNA) in young volunteers as compared with zinc porcine insulin (Monotard). AB - Zinc human insulin (recombinant DNA) or zinc PPI (Monotard) 20 U was injected subcutaneously to study the time-action profile in six healthy volunteers. During the test period they received a 10-g biscuit containing 3% moisture, 7% protein, 10% fat, 80% carbohydrate, and 30 ml of water every hour. The onset of action with zinc human insulin occurred earlier than with zinc PPI. Also, the intensity of the blood sugar-lowering effect was more pronounced 3 and 4 h after administration of insulin. No other statistically significant differences were detected between the two blood glucose curves. The results show that it is possible to develop a zinc human insulin formulation with a duration of the blood sugar-lowering effect equal to a zinc PPI formulation. PMID- 6927742 TI - Decreasing self-stimulatory behavior with physical exercise in a group of autistic boys. AB - Five autistic boys were observed during 27 language training sessions. Each session followed one of three periods: physical exercise, TV watching, or regular academic work. It was found that the lowest levels of self-stimulation followed physical exercise, there were no differences in the levels of self-stimulation following TV watching and following academics, and the levels of correct question answering were not affected by the three different previous periods. PMID- 6927743 TI - Hemodialysis as a treatment for infantile autism. AB - A course of 10 weekly hemodialyses was conducted on a young adult female with infantile autism. Multiple parameters were measured to assess outcome. No significant changes were noted in her mood, behavior, or cognitive functioning. Several other autistic individuals were evaluated for the study but were felt to have either behavioral or cognitive limitations, which made the procedure unsafe. It is concluded that hemodialysis in a larger group of autistic individuals was not justified. PMID- 6927739 TI - Abnormal hemoglobin variant: a source of error in chromatographic determination of HbA1. PMID- 6927744 TI - Classification of abnormal children: discrimination learning ability. AB - Large individual differences exist among psychotic and retarded children, and a procedure that would enable classification of discrimination learning ability would be of value. A procedure designed to assess the discrimination learning thresholds of low-functioning children is described. A performance index (PI) that reflects accuracy of discriminative responding, difficulty of the discriminations attained, and learning rate was found to correlate significantly with mental age, intelligence quotient, Vineland Social Age, Vineland Social Quotient, and language functioning, but not with chronological age. The question of the optimal magnitude of correlation between a new measure and existing measures is discussed. PMID- 6927745 TI - A comparison of cognitive development in normal and psychotic children in the first two years of life from home movies. AB - Through the use of an unusual data base--home movies made by parents of the infancies and early childhood of their children who later developed a form of childhood psychosis and a control group of equal number who developed normally- the investigators studied the intellectual development of these children. Behaviors indexing Piaget's sensorimotor stages were recorded for both the index and control groups. The findings show several differences between index and control groups. Further, three aberrant cognitive patterns appeared in the sensorimotor behaviors of the subsequently psychotic children. These findings are discussed in relation to specific diagnosis and case history information. PMID- 6927746 TI - Thyroid hormone in autistic children. AB - Thyroid hormone plays an important role in the pre- and postnatal development and function of the central nervous system. Disturbances in thyroid hormone regulation have been hypothesized in childhood autism. We evaluated blood indices of thyroid function, including serum thyroxine, triiodothyronine, and thyroid stimulating hormone, in a large population of autistic children. No differences were found between autistic and normal children. PMID- 6927747 TI - A calibration approach to improve measurement accuracy. PMID- 6927748 TI - Validation and routine operation of a sterile dry powder filling facility. PMID- 6927749 TI - The determination of intrinsic activation energies of specific acid-base catalyzed reactions. PMID- 6927750 TI - Physiochemical stability of pharmaceutical phosphate buffer solutions. IV. Prevention of precipitation in parenteral phosphate solutions. PMID- 6927751 TI - Antioxidants in pharmaceutical products. PMID- 6927753 TI - Psychiatric diagnosis of patients requesting sex reassignment surgery. AB - This paper presents the psychiatric diagnostic findings on 51 patients who requested Sex Reassignment Surgery. The biologic females, as a group, were significantly healthier than the males. Ninety-two percent of the males and 58% of the females had psychiatric diagnoses, apart from gender dysphoria. Most of the abnormalities in both groups were character disorders; eight percent of the patients, however, were schizophrenic. Psychometric evaluation suggested that approximately one-half of the patients had more serious disorders than were indicated during clinical evaluation. The initial and ongoing diagnostic processes are helpful in the pre- and postoperative management of patients with gender dysphoria. PMID- 6927752 TI - Sexual attitudes of psychogenic and organic impotence. AB - Thirty organically impotent men were contrasted with 21 psychogenically impotent men and 17 normal controls. Distinctions among sexual attitudes, sexual behaviors, and sexual interests were evaluated on the Sex Form. Results suggest that impotent men can be reliably distinguished from non-impotent men on the basis of their use of activity rather than fantasy in coping with life's problems and their interest in receiving treatment for their condition. Separate comparisons between the control group and the two impotent groups further suggest that both can be reliably distinguished from normals. It is more difficult, however, to distinguish between organically and psychogenically impotent men on the basis of sexual interests, attitudes, and behavior. The findings suggest, however, that impotent men generally and psychogenically impotent men in particular tend to be individuals who have relatively low sexual drive, diminished sexual knowledge, and who are prone to active ways of coping with stress. The results are discussed in light of previous findings. PMID- 6927755 TI - Marriage and mental health. AB - Evidence linking psychiatric impairment with divorced marital status and the presence of marital discord is reviewed. Various theoretical models to explain these relationships are considered. Divorced marital status and marital discord are related to psychiatric impairment and mental health service utilization. Available evidence suggests that part of the impairment in these populations is secondary to factors involved in the breakdown of marital relationships and not completely explainable by premarital hypotheses. This has implications for mental health administrators. PMID- 6927754 TI - Sexual therapy for the post coronary patient. AB - This paper examines the theory and research on the subject of sexual activity post myocardial infarction. An etiological model of sexual dysfunction following MI is presented, treatment implications from the model are discussed, and a treatment program with specific interventions is discussed. Extensions of the conceptual model and treatment outline result in a format for feasible "preventative" therapy implemented immediately following the cardiac event. Emphasis is placed on the systemic etiology and effects of sexual dysfunction. PMID- 6927756 TI - A system of group therapy for the treatment of marital and sexual dysfunction. AB - So many patients who present with sexual difficulties cannot be treated successfully with the new sex therapies because of difficult interpersonal or intrapersonal stresses. This paper presents a system of interlocking group psychotherapies to help deal with the problems in such a way that the reversal of the sexual dysfunction can also be undertaken with one or several varieties of group therapy as the primary modality of treatment. Concomitant individual therapy sessions or conjoint therapy sessions are also held as needed. A dual sex therapy team approach is used in the group setting and the method has the additional advantage of allowing the two members of the treatment team to treat a large number of patients with marital and sexual difficulties in an ongoing therapy program. PMID- 6927759 TI - Comparison of six selective media for recovering Salmonella. PMID- 6927757 TI - Motivation in conjoint therapy. AB - In conjoint therapy the motivation of each partner is a central issue, and is a curiously neglected area. While one or both spouses may have "low" motivation for working towards a more functional marriage, they may have very powerful other motivations for seeking conjoint therapy. This paper, derived from a review of 100 couples seen in conjoint therapy, outlines the seven most common alternative motivations encountered, and offers some diagnostic clues and management techniques. PMID- 6927763 TI - Haematological aspects of lymphomas. PMID- 6927764 TI - Heterogeneity of tetracycline resistance determinants. PMID- 6927765 TI - Involvement of the cell envelope in plasmid maintenance: plasmid curing during the regeneration of protoplasts. PMID- 6927766 TI - Complementation of a plasmid replication defect by autonomous incompatible plasmids in Staphylococcus aureus. PMID- 6927767 TI - The segregation of kinetoplast DNA networks in Trypanosoma brucei. PMID- 6927768 TI - Thermoluminescent dosimeters for in vivo measurement of radiation exposure and related dose in mammography. AB - Most methods of radiation exposure evaluation in mammography concentrate on in vitro determination. One method has evolved using thermoluminescent dosimeters (TLDs) for in vivo determination, yet on a mail order basis. Presented here is the development of a procedure for preparing and using TLDs to measure entrance skin exposure (ESE) and mammographic unit output consistency that was adapted for implementation within a hospital setting. Using published correction factors and absorbed dose data, the estimated midbreast dose was calculated from the ESE obtained. A two-view examination resulted in an average ESE of 2198 mR per breast and an average midbreast dose of 177 mRad. This procedure is feasible for assessing ESE and dose in mammography. PMID- 6927769 TI - Erbium filtration in iodine contrast studies. AB - In iodine contrast studies, an improvement in contrast is theoretically possible by narrowing the energy spectrum around the k-edge of iodine. Heavy metal filtration is a method of narrowing the energy spectrum but other parameters of the examination may be altered. These other parameters must be examined. After establishing the effect of heavy metal (erbium) filtration on the beam energy, the filter is evaluated in a simulated clinical situation. Patient exposure, image contrast, and tube loading are monitored while obtaining radiographs of a phantom comparable to a standard radiograph of the phantom. From this study, it was determined that erbium filtration could be used to decrease patient exposure markedly without significant loss of contrast or an increase in tube loading. Also determined was a set of exposure factors at which the erbium filtration was most effective. PMID- 6927770 TI - Increasing radiographer productivity by an incentive point system. AB - Because of a very low technologist productivity in their Radiology Department, the authors describe a Productive Point System they developed and implemented to solve this personnel problem. After establishing the average time required to perform all exams, point credits (one point for every ten minutes utilized) were assigned to each exam performed, thereby determining an index of production. A Productive Index of 80% was considered realistic and was the equivalent of 192 points for a 40-hour work week. From 1975 to 1978 personal productivity increased from 79% to 113%. This resulted in an average yearly fiscal savings of over $20,000.00 for this three-year period. There was also a significant improvement in exam efficiency and quality, job attitude, personnel morale, and public relations. This program was highly successful because technologist acceptance and cooperation was complete, and this occurred mainly because the system supports the normal occupational goals and expectations of technologists. PMID- 6927771 TI - An interactive program to calculate the treatment time for 60Co single beam, opposing beam, and rotational beam radiation therapy. AB - An interactive computer program for calculating treatment times for 60Co single beam, opposing beam, or rotational beam radiation therapy is described. The program allows the user to enter parameters specific to his machine. Analytic expressions are used to represent the depth dose, backscatter factor, tissue-air ratio, collimator factor, and beam attenuation of a block-carrying tray. PMID- 6927773 TI - An effective method of cassette identification. PMID- 6927774 TI - Non crossover film. PMID- 6927775 TI - Erect position/tangential projection of the patellofemoral joint. AB - This paper presents an erect position, using 40 degrees knee flexion and a vertical central ray, as a simple alternative to help overcome the problems encountered with the standard "sunrise" view of the patella and patellofemoral joint. PMID- 6927772 TI - A method for the construction of x-ray shielding masks. AB - A method is described for the production of a rigid model of a patient's face onto which lead shielding sheets may be contoured. The model is cast in Lipowitz's metal using a plaster mold. PMID- 6927776 TI - Disease in the elderly: social factors. AB - Hypochondriasis, the most common social problem as regards disease in the elderly, is discussed, with some possible strategies for action by the radiographer. PMID- 6927777 TI - Intraoperative radiotherapy. AB - Intraoperative radiotherapy is the term applied to irradiation of unresectable tumors, partially resectable tumors, and regional lymph nodes with external beam radiation at the time of surgical exposure. The procedure is a promising supplement to conventional therapy; it presents no special surgical problems, and it is well tolerated. PMID- 6927778 TI - Adult learners: are they really different? AB - Some knowledge of adult learning is essential in establishing a meaningful learning/teaching experience that will meet the needs of our students, employees, and patients. Specific learning characteristics that pertain directly to the adult, such as fluid and crystallized intelligence, problem-solving ability, the role of experience, and physiologic changes, strongly indicate a uniqueness in the way adults learn. PMID- 6927779 TI - A radiation exposure meter for technologists. AB - The need for Quality Assurance Programs has made it necessary for the technologist to have an accurate yet simple to use instrument for measuring radiation exposure. A unique commercial instrument is described that can help the technologist determine radiation output, half value layer, mAs reciprocity, and fluoroscopy exposure rates. The ability of the technologist to make these measurements will lead to reduction of repeat films and radiation exposure to the patient. PMID- 6927780 TI - The radiology research technologists: who are they? AB - Over the years, radiology research has expanded its application due to the tremendous advances in imaging technology and the expanding role of the radiologist in the care and management of the patient. This paper is intended to provide insight into the activities and role of the radiologic technologist in radiology research today. PMID- 6927781 TI - Repeated gonorrhea in Sheffield: the size of the problem, epidemiologic significance, and personal characteristics of repeaters. AB - A retrospective study was made of patients in Sheffield who had had repeated gonorrhea infections during 1976-1979. Repeaters--defined as individuals with at least one gonococcal reinfection within 12 months of their index infection in any year--were a constant proportion of the absolute number of individuals infected in any calendar year. Thus, an average of 18.2% of individuals were repeaters who contributed 30.3% of the annual number of heterosexually acquired gonococcal infections. Repeaters of either sex were more likely to be young, unmarried, unemployed, and black; they more commonly had a history of preceding sexually transmitted infections, other sexually transmitted diseases accompanying their gonorrhea, and gonococcal isolates relatively resistant to penicillin. Discriminant analysis of their characteristics suggests that potential repeaters might be predicted. It is hypothesized that the local incidence of gonorrhea is directly proportional to the number of repeaters, and it is felt that control endeavors should be focused on potential repeaters if the incidence of this disease is to be reduced. PMID- 6927782 TI - Evaluation of a sexually transmitted diseases training program. AB - To determine whether attendance at a sexually transmitted disease (STD) training course produces an immediate and/or sustained gain in knowledge and to assess whether practitioners who might benefit most from such training could be identified easily, 55 practitioners were given one or more standardized written examinations before, immediately after, and four to 15 months after attendance at one of eight intensive one- or two-week training sessions. All practitioners (nine physicians and 46 physician extenders) increased their clinical knowledge of STDs, and most retained this knowledge over a four- to 15-month follow-up period (P less than 0.001). Practitioners with the lowest scores before the course had the least professional training, graduated from professional schools prior to 1965, had less than two years of work experience in STDs, and examined the fewest patients per day (P = 0.028). A lower precourse score was predictive of significant improvement on the postcourse test (P less than 0.001). Our results show that attendance at an STD training course produces both an immediate and a sustained gain in knowledge and indicates that precourse test scores and practitioner characteristics can be useful in identification of practitioners most in need of and most likely to benefit from STD clinical training. PMID- 6927784 TI - Late yaws: a case report. AB - A case of late yaws in a young Omani man is described. The patient had bone and joint deformities and hyperkeratotic lesions of the palm and sole. The differential diagnosis of the nonvenereal treponematosis is discussed in the light of the clinical and laboratory findings and the patient's history. PMID- 6927783 TI - Isolation of Branhamella (Neisseria) catarrhalis from men with urethritis. AB - Branhamella (Neisseria) catarrhalis was recovered from urethral exudates of three men with acute urethritis. In all cases gram stain of the urethral exudates revealed intracellular gram-negative diplococci morphologically compatible with Neisseria gonorrhoeae. Branhamella (Neisseria) catarrhalis should be considered as a potential cause of acute urethritis in men with urethral discharge microscopically consistent with, but culture-negative for, N. gonorrhoeae. PMID- 6927785 TI - The unique considerations and concerns of the homosexual patient receiving care for sexually transmitted diseases. PMID- 6927786 TI - Fifth international symposium on human chlamydial infection. PMID- 6927788 TI - [Studies on the defense mechanisms in the respiratory system. Report II. Studies on lysozyme as a defense factor against infection]. PMID- 6927789 TI - Studies on regional differences in pre-inspiratory lung volume and pre inspiratory alveolar N2 concentration by a single breath method. PMID- 6927787 TI - [Subtypes H1N1 and H3N2 of influenza virus isolated from the same patient]. PMID- 6927790 TI - [A case of mediastinal cavernous hemangioma]. PMID- 6927791 TI - Meiosis in Coprinus: characterization and activities of two forms of DNA polymerase during meiotic stages. AB - Two forms of DNA polymerase have been studied in the basidiomycete Coprinus. DNA polymerase from basidiocarp tissues at zygotene-pachytene stage has been purified 3,500-fold and defined as DNA polymerase b by virtue of its insensitivity to N ethylmaleimide and by its low molecular weight (76,000). This enzyme has optimal activity at pH 7.0 to 7.5, at 200 mM KCl, and at 25 degrees C incubation temperature. It can use polycytidylic acid-oligo(dG)12-18 as template primer in addition to homodeoxypolymers. The DNA polymerase a is mainly produced in the exponentially growing mycelium. It is sensitive to N-ethylmaleimide and has a temperature optimum at 35 degrees C. At the premeiotic S phase, activities from both polymerase a and polymerase b are found in cell-free extracts. The b enzyme is the only DNA polymerase produced during meiotic prophase. Its assayable activity exhibits two peaks, one at premeiotic S stage and one at pachytene. It is possible that DNA polymerase b is responsible for pachytene repairs involved in recombination. PMID- 6927794 TI - International symposium on health effects of drinking water disinfectants and disinfectant by-products. Sponsored by the U.S. Environmental Protection Agency. Cincinnati, Ohio April 21-24, 1981. PMID- 6927792 TI - Topographical distribution of 5-methylcytosine in animal and plant DNA. AB - The topographical distribution of 5-methylcytosine on animal and plant cell DNA has been examined with methyl-sensitive restriction enzymes and gel electrophoresis analysis. These DNAs digested with the enzyme HpaII have a partially bimodal size distribution, indicating the existence of clusters of methylated and unmethylated CCGG sites in the DNA. By analyzing the methylation state of all CG moieties in restricted DNA fractions, it was possible to show that these genomes are, in general, arranged as clusters of relatively highly methylated and undermethylated regions. Plant DNA also contains 5-methylcytosine in the prototype sequence C-X-G. Restriction of this DNA with EcoRII revealed that these methyl groups are also distributed in clusters, suggesting that this is a general phenomenon. The undermethylated areas may correspond to the active fraction of the genome. PMID- 6927797 TI - Sanctions for failure to disclose medical malpractice experts. Mendelson v. Feingold. PMID- 6927795 TI - The present status of physician privileges. PMID- 6927793 TI - Localization of kinetoplast DNA maxicircle transcripts in bloodstream and procyclic form Trypanosoma brucei. AB - Over 80% of the maxicircle and numerous minicircles of Trypanosoma brucei kinetoplast DNA have been cloned. The uncloned maxicircle segment contains few restriction endonuclease cleavage sites, varies in size among strains, and may be unstable in conventional cloning systems. cDNA prepared to bloodstream or procyclic trypomastigote RNA hybridized to all but one maxicircle segment, but did not hybridize to minicircles. Fourteen maxicircle transcripts were detected in RNA from both bloodstream and procyclic trypomastigotes. The coding sequences for these transcripts were localized and account for most of the maxicircle. One region of the maxicircle, which borders the variable region, was not found to be transcribed. We conclude that the maxicircle is largely but not completely transcribed in both bloodstream and procyclic trypomastigotes, whereas minicircle transcription is minimal or absent in these stages. Qualitative transcriptional differences which could account for mitochondrial respiratory differences between the bloodstream and procyclic trypomastigotes were not observed. PMID- 6927796 TI - Informed consent. PMID- 6927798 TI - Fracture dislocation of sacroiliac joints and the symphysis pubis--evidence deposition of plaintiff's orthopedic surgeon. PMID- 6927799 TI - Negligent infliction of emotional distress by physicians and hospitals. PMID- 6927800 TI - Malignant hyperthermia during general anesthesia: medico-legal considerations. PMID- 6927801 TI - Implantable medical devices and products liability. PMID- 6927802 TI - Wrongful life. PMID- 6927803 TI - Child abuse and neglect: a survey of the law. PMID- 6927804 TI - Paternity case--direct and cross-examination of plaintiff's expert immunohematologist. PMID- 6927805 TI - Patient noncompliance documentation: a tactic for successful medical malpractice prevention and defense. PMID- 6927808 TI - Cronapaque photographic prints of X-rays for the modern trial. PMID- 6927806 TI - Psychiatric treatment of women: standard of care? PMID- 6927807 TI - Tetrachloroethylene: a cause of permanent kidney damage. PMID- 6927811 TI - Medical implants and the law. PMID- 6927815 TI - Plasmid pEA566 from Erwinia aroideae. AB - A new plasmid designated pEA566 was isolated from Erwinia aroideae. The molecular weight of the plasmid, as determined by neutral and alkaline sucrose gradient centrifugation, electron microscopy, and agarose gel electrophoresis, was 6.6 X 10(6). The plasmid replicated under relaxed control, had three cleavage sites for KpnI restriction endonuclease, and no sites for EcoRI, BamHI, SalI, PstI, and HindIII. PMID- 6927809 TI - Legal implications of artificial conception. Making babies makes law. PMID- 6927812 TI - Wrongful death--enovid therapy for endometriosis--malpractice--discovery deposition of defendant gynecologist's expert. PMID- 6927810 TI - The medical examination of the live rape victim and the accused. PMID- 6927813 TI - Electron microscopic mapping of deletions on a streptococcal plasmid carrying extraordinarily long inverted repeats. AB - Deletions delta 101, delta 102, and delta 103 which occurred within the extraordinarily long inverted repeats of the self-ligated large EcoRI fragment of the streptococcal MLS (macrolides, lincosamides, streptogramin B)-resistance plasmid pSM19035 led to the formation of plasmids pDB101, pDB102, and pDB103. Their molecular lengths were determined by contour length measurements to be 17.8, 17.4, and 13.9 kb, respectively. Electron microscopic examination of self annealed molecules revealed stem-loop structures with inverted repeats comprising 41 to 91% of the mass of plasmids. Two unique sequences (US1 and US2) separated the inverted repeats in the case of pDB101 and pDB103, while in pDB102 the repeats were joined at one end and separated at the other by a unique sequence (US2). The size of the unique sequence US2 was identical for all three plasmids, and the location of the resistance determinant was determined by electron microscopic examination of self-annealed molecules of the recombinant plasmid pDB201. Mapping of the deletion termini, accomplished by combining electron microscopic and HindIII restriction data, suggested that deletions may occur at preferential sites. PMID- 6927814 TI - Mode of inheritance and evidence for cistron heterogeneity of chloroplast 16S ribosomal RNA genes in Nicotiana. AB - Oligonucleotide maps (fingerprints) of T1 RNase digests of 125I-labeled 16 S chloroplast rRNA of Nicotiana tabacum and N. gossei revealed the presence of T1 oligonucleotide fragment 100 in the 16 S rRNA of N. gossei while N. tabacum 16 S rRNA had a unique T1 oligonucleotide (fragment 101) as well as some fragment 100. From the positions in the fingerprints and from fingerprints of secondary enzymatic digestion of the fragments, we conclude that fragments 100 and 101 are similar in sequence and size, but fragment 100 probably contains an extra uracil residue. This difference is shown to be maternally inherited, thus confirming the location of 16 S chloroplast rRNA genes on chloroplast DNA and ruling out the possibility of genetically active chloroplast rRNA genes in the nucleus. The presence of both fragments 100 and 101 in N. tabacum may indicate sequence heterogeneity between the two cistrons for 16 S chloroplast rRNA. These results demonstrate the feasibility of determining the inheritance of organelle genes by genetic analysis of their primary transcripts. PMID- 6927816 TI - Quantitative EEG and psychometric analyses in assessing CNS-activity of Ro 13 5057--a cerebral insufficiency improver. AB - In a double-blind, placebo-controlled cross-over study, the encephalotropic, psychotropic and pharmacodynamic properties of Ro 13-5057/001, a new 2 pyrrolidinone derivative, were investigated in 10 geriatric subjects. They received in randomized order at weekly intervals, single oral doses of placebo, 250 mg, 500 mg and 1000 mg Ro 13-5057, as well as 2000 mg pirazetam as reference drug. EEG recordings, psychometric testing and evaluation of blood pressure, pulse rate and side effects were carried out at the hours 0, 2, 4, 6, 8 and 24. Power spectral density analysis of the EEG demonstrated Ro 13-5057 to be an encephalotropic drug, as statistically significant CNS changes occurred in comparison to placebo, which were characterized by a decrease of delta activity, increase of alpha activity and slow beta activity and acceleration of dominant frequency. The reference drug 2000 mg pirazetam induced similar changes. Such alterations were previously described by us as typical for certain antihypoxidotic/nootropic drugs and are indicative of improvement in vigilance. Psychometric data confirmed this interpretation of neurophysiological alterations as shortening of reaction time, acceleration of tapping speed, CNS activation as measured by the Archimedean spiral, improvement in mood as well as improvement in qualitative but deterioration of quantitative aspects of attention were observed at various times after the active substances as compared with placebo. Regarding time-efficacy, the peak effect in CNS changes was noted in the 2nd hour after Ro 13-5057, but interestingly there were also alterations as late as 24 hours after oral administration. Dose-efficacy curves suggested 1000 mg Ro 13-5057 as the most effective compound of the study. The lack of side effects and clinically relevant changes in blood pressure and pulse rate indicates that the drug is well tolerated in man. PMID- 6927817 TI - [44th annual meeting of the Japanese Circulation Society. 26-28 March 1980, Nagoya, Japan. Abstracts]. PMID- 6927818 TI - [In vitro resorption study of a new anti-arrhythmia compound, N-(3,3-diphenyl propyl)-N'-(1-phenyl-2-propyl)1,3-propylene diamine dihydrochloride]. PMID- 6927819 TI - Nomifensine test does not differentiate hyperprolactinemia associated with and without radiologic abnormalities in the sella turcica. AB - A group of 17 hyperprolactinemic women was given 200 mg of nomifensine orally to evaluate its diagnostic potential to discriminate between tumors and nontumorous hyperprolactinemia. The nomifensine suppressive effect on prolactin serum levels was not significantly different between patients with or without enlargement of the sella turcica. A control group of 5 women with normal prolactin levels exhibited a nomifensine suppressive effect below 65% of the baseline prolactin level, which was significantly different from that in the hyperprolactinemic group. In conclusion it is confirmed that the nomifensine test provides no value in the early diagnosis of the prolactinoma. PMID- 6927820 TI - Prolactinemia in exercising male athletes. AB - 8 male collegial athletes were submitted at random to three (55, 70 and 85% of VO2 max) ergocycle exercises of 20-min duration. Venous blood samples were obtained before, during and after ergocycling sessions by antecubital catheterization. Serum prolactin was measured by RIA using specific antiserum. The exercise treatments induced a blood prolactin response proportional to the intensity of the work loads. PMID- 6927821 TI - A study of the action of anticonvulsant drugs on an experimental model of epilepsy. AB - Repeated electrical low intensity stimulation of various regions of the brain has been shown to induce epileptic seizure activity. This experimental model of epilepsy has been used in our laboratory in rats. Male rats, anaesthetized with nembutal (20 mg/kg, i.p.) and ketalar (60 mg/kg, i.p.) were implanted stereotaxically with electrodes in the dorsal hippocampus and neocortex and received 2 hours stimulation sessions via the hippocampal electrodes (1 sec, 60 Hz, 200-800 microA) one stimulus per minute, during which electrographical and behavioral seizures were induced. The effect of anticonvulsant drugs was tested on this model: phenobarbital (40 mg/kg) reduced the quantity of epileptic electrographic activity and abolished the behavioral aspects of the seizures; diphenylhydantoin (20 mg/kg) reduced the quantity of epileptic electrographic activity, but had no effect on the behavioral component of the seizures; diazepam (6 mg/kg) only blocked the behavioral component of the seizures leaving the animal stuporous and immobile, but the electrographical component was unaffected; carbamazepine (10 mg/kg) had no effect on the electrographical epileptic seizures and reduced the behavioral aspects, but to a lesser extent than diazepam. PMID- 6927822 TI - Isometric responses in the denervated diaphragmatic muscle of the guinea pig elicited by antigen and histamine. AB - Denervated diaphragmatic muscle strips from the guinea pig responded in vitro to varying concentrations of histamine with isometric contractions. Dose-response curves from strips taken from several areas of the muscle (ventral, V; dorsal, D; lateral, L) had slopes which were related in the following manner: D greater than V greater than L. Nevertheless, when the curves were normalized with respect to a dose which produced maximal tension, the slopes were similar and could be superimposed. Preparations taken from animals allergized to either bovine serum albumin or ferritin responded to the antigen with isometric contractions which also differed according to the original location of the strip in the muscle (D greater than V greater than L), but were similar when normalized as above. The results obtained from the normalized curves reflect a uniform sensitivity to histamine and antigen throughout the muscle. The variations in tension developed in the different strips probably are related to their contractile mass. The isometric recordings also revealed the development of spontaneous muscular contractions, as well as the presence of response latencies to both histamine and antigen, but not to acetylcholine. PMID- 6927823 TI - Electrolyte excretion in adrenalectomized rats submitted to cholinergic stimulation of the lateral hypothalamic area (LHA). PMID- 6927824 TI - The detection of members of the olivanic acid family in Streptomyces gedanensis. PMID- 6927825 TI - Cervical condylomatous atypia and its relationship to cervical neoplasia. PMID- 6927826 TI - Negotiating an employment contract. PMID- 6927827 TI - Adolescent idiopathic scoliosis. AB - Adolescent idiopathic scoliosis, a lateral curvature of the spine, is an insidious disorder that usually occurs in previously well children. The onset is generally during the growth spurt of the early teens. While a potentially disabling disease entity, serious deformity can be averted through early detection and proper management. The nurse can be instrumental in this procedure by learning the necessary examination techniques and conscientiously screening all susceptible patients entering the health care setting. PMID- 6927829 TI - The self-help/self-care concept. PMID- 6927828 TI - [Comparative evaluation of methods of isolating N-benzoylbarbiturates]. PMID- 6927830 TI - Gastric hormones. PMID- 6927831 TI - Gender and the nurse practitioner role. AB - Many nurse practitioners are recognizing that some role development problems arise because they are women seeking more power and responsibility in a traditionally male-dominated world. Specific keys to reduce these pressures are given for the nurse practitioner. PMID- 6927832 TI - Study on the relationship between isolation of mycobacteria and classical microbiological and chemical indicators of water quality in swimming pools. AB - Observation of skin lesions in patients who frequent swimming pools in the dermatology section of the Nancy Hospital, coupled with isolation of Mycobacteria marinum led to a preliminary survey of 20 swimming pools in the Lorraine region for Mycobacteria. Six representative pools were then chosen for more in-depth research during 1977 and 1978: 3 chlorinated, 2 brominated and 1 ozonated pool. The following parameters were analyzed: chemical (pH, conductivity, residual disinfectant, and oxidizable matter by potassium permanganate); microbiological (standard plate counts, total and faecal coliforms, Streptococci, Clostridia, Mycobacteria, and pathogenic Staphylococci). During the survey, different species were isolated: saprophytic Mycobacteria such as M. gordonae, M. flavescens, M. terrae, M. aurum and M. parafortuitum; and opportunistic pathogens such as M. marinum, M. kansasii, and M. fortuitum. There was no correlation between the presence of Mycobacteria and classical microbiological indicators. In one pool, M. marinum was repeatedly isolated, this same pool supplied by thermal water was being used by some patients with skin granuloma. Increased chlorination eliminated this pathogenic species. The level of saprophytic Mycobacteria was very low while opportunistic Mycobacteria were absent in pools with a residual chlorine concentration of only 0.5--0.6 mg/l. The same results were found for brominated pools with a residual of 2 mg/l, and for the ozonated pool without a residual. The Mycobacteria contamination was due partly to the water which replaced eliminated water and partly to swimmers and pool surfaces (walls, floor). PMID- 6927835 TI - [Let us improve the medical support for Navy personnel]. PMID- 6927834 TI - [Let the work of military sanitoria meet the level of present demands]. PMID- 6927833 TI - Diagnostic protocol: secondary amenorrhea. Part 1. PMID- 6927836 TI - Human extra-embryonic membranes: role of trophoblast in normal and abnormal pregnancies. AB - The human embryo is encased in extra-embryonic membranes which are covered with trophoblast throughout pregnancy. Bits and pieces of trophoblast break away from the placenta and are swept into the mother's circulation to lodge in her lungs without causing evidence of inflammation or rejection. This is in part due to an absence of histocompatibility antigens from trophoblast membranes, but it may also be due to a structural glycoprotein which is capable of inhibiting allogeneic recognition and rejection reactions. Another glycoprotein of the trophoblast is shared with lymphocytes, and serological studies have shown this to be polymorphic. Evidence has also been accumulated that this genetically determined cell membrane component is associated with the major histocompatibility complex, and that maternal recognition of this may be necessary to produce blocking factors that protect trophoblast from maternal rejection. Women who lack these factors during pregnancy tend to abort, and some of these patients also share several HLA antigens with their husbands. In an effort to produce blocking factors artificially, four aborting women were immunized with trophoblast-lymphocyte cross-reactive antigens, and this has resulted in normal pregnancies and the delivery of healthy babies at term. This finding suggests that genetical diversity of HLA is associated with TLX antigens, thus providing a mechanism whereby HLA not only generates but is also responsible for the perpetuation of diversity in human populations. PMID- 6927837 TI - [Cerebral edema following experimental subarachnoid hemorrhage (author's transl)]. AB - Despite the fact that cerebral edema appears to be a common complication of subarachnoid hemorrhage (SAH) due to a ruptured cerebral aneurysm, measurements of brain tissue water content have not been carried out in this entity. For this reason, the development of cerebral edema has been analized in a newly developed experimental SAH model. SAH was induced in cats under controlled ventilation by withdrawing needles previously pierced into one or both infraclinoid internal carotid arteries through a unilateral transorbital approach. Intracranial pressure (ICP), blood pressure, cortical EEG and somatosensory evoked potentials (SEP) to sciatic nerve stimulation were monitored for 3 to 24 hours. Using labelled microspheres of 15 mu diameter, four serial determinations of regional cerebral blood flow (rCBF) were performed in one group of five animals before and immediately after SAH as well as 10 to 20 min, and 3 to 6 h post SAH. RCBF were obtained in 60 areas of the brain from tissue samples weighing about 150 mg. Brain tissue water content was determined by the vacuum freeze-drying weighing procedure in the same brain samples. In another group of five, brain tissue specific gravity (SG) was measured by microgravimetry in samples of brain tissue weighing 30 to 50 mg. Regional differences in SG as well as in water content were calculated from 21 untreated control animals.+2 PMID- 6927838 TI - Sudden infant death syndrome. PMID- 6927839 TI - Pharmacy update. Part 2. New drugs released in 1980 and 1981. PMID- 6927840 TI - Nucleotide sequence of human preproinsulin complementary DNA. AB - Recombinant bacterial plasmids that contain DNA complementary to human preproinsulin messenger RNA have been constructed. One clone contains the entire preproinsulin coding region, as well as the 3' untranslated region of the messenger RNA and eight nucleotides of the 5' untranslated region. Additional sequence information for the 5' untranslated region was obtained with the use of insulinoma messenger RNA in conjunction with specific primers from the cloned DNA for enzymatic chain termination sequence analysis. The results confirm the amino acid sequence of human proinsulin previously determined, and predict the amino acid sequence of the human preproinsulin signal peptide. PMID- 6927843 TI - Nucleotide sequences at the 5'-termini of the alfalfa mosaic virus RNAs and the intercistronic junction in RNA 3. AB - Nucleotide sequences at the 5'-termini of the alfalfa mosaic virus genomic RNAs and the intercistronic junction in RNA 3 were deduced and compared to identify possible common recognition signals for replicating enzymes in the corresponding minus-stranded viral RNAs. Homology between the 5'-terminal sequences is less than 11 nucleotides and no complementarity with the homologous sequence occurring at the 3'-end of the viral RNAs was observed. Homology between the 5'-terminus and intercistronic region in RNA 3 is compatible with the synthesis of subgenomic RNA 4 by internal initiation of transcription on the RNA 3 minus strands. The sequence around the intercistronic junction can be folded into a very stable secondary structure. PMID- 6927844 TI - Replication of mouse adenovirus strain FL DNA. PMID- 6927842 TI - The nucleotide sequences of the initiator transfer RNAs from bean cytoplasm and chloroplasts. AB - The initiator tRNAsMet from the cytoplasm and chloroplasts of Phaseolus vulgaris have been purified and sequenced. The sequence of bean cytoplasmic initiator tRNAiMet is : pA-U-C-A-G-A-G-U-m1G-m2G-C-G-C-A-G-C-G-G-A-A-G-C-G-U-m2G-G-U-G-G-G2 C-C-C-A-U-t6A-A-C-C-C-A-C-A-G-m7G-D-m5C-C-C-A-G-G-A-psi-C-G-m1A-A-A-C-C-U-Gm-G-C U-C-U-G-A-U-A-C-C-AOH. The sequence of bean cytoplasmic tRNAiMet is almost identical to that of wheat germ and shows a high degree of homology with other cytoplasmic initiator tRNAs. The sequence of bean chloroplast initiator tRNAfMet is : pC-G-C-G-G-A-G-U-A-G-A-G-C-A-A-C-U-U-Gm-G-D-A-G-C-U-C-G-C-A-A-G-G-C-U-C-A-U A-A-C-C-U-U-G-A-A-m7G-acp3U-U-A-C-G-G-G-T-psi-C-A-A-A-U-C-C-C-G-U-C-U-C-C-G-C-A-A C-C-AOH. Bean chloroplast initiator tRNAfMet sequence shows procaryotic characteristics at the 5' end of the acceptor stem and in the TpsiC loop, but also contains some distinctive features. PMID- 6927841 TI - Cloning of influenza cDNA ino M13: the sequence of the RNA segment encoding the A/PR/8/34 matrix protein. AB - A strategy has been developed for sequencing the single-stranded RNA genes of influenza virus. Restriction fragments derived from double-stranded cDNA copies of total influenza RNA were cloned into the bacteriophage M13mp2 and sequenced by the dideoxy technique. Sequences were extended and overlapped by using the virion RNA as template and priming with small restriction fragments. In the course of this strategy, the nucleotide sequence of segment 7 (1027 nucleotides) was completed and provides the primary structure of the matrix protein (27, 861 daltons). In addition, there is a second long reading frame which partly overlaps the reading frame of the matrix protein. PMID- 6927845 TI - Sequence determination and analysis of the 3' region of chicken pro-alpha 1(I) and pro-alpha 2(I) collagen messenger ribonucleic acids including the carboxy terminal propeptide sequences. AB - Three pro-alpha 1 collagen cDNA clones, pCg1, pCg26, and pCg54, and two pro-alpha 2 collagen cDNA clones, pCg 13 and pCg45, were subjected to extensive DNA sequence determination. The combined sequences specified the amino acid sequences for chicken pro-alpha 1 and pro-alpha 2 type I collagens starting at residue 814 in the collagen triple-helical region and continuing to the procollagen C-termini as determined by the first in-phase termination codon. Thus, the sequences of 272 pro-alpha 1 C-terminal, 260 pro-alpha 2 C-terminal, 201 pro-alpha 1 helical, and 201 pro-alpha 2 helical amino acids were established. In addition, the sequences of several hundred nucleotides corresponding to noncoding regions of both procollagen mRNAs were determined. In total, 1589 pro-alpha 1 base pairs and 1691 pro-alpha 2 base pairs were sequenced, corresponding to approximately one-third of the total length of each mRNA. Both procollagen mRNA sequences have a high G+C content. The pro-alpha 1 mRNA is 75% G+C in the helical coding region sequenced and 61% G&C in the C-terminal coding region while the pro-alpha 2 mRNA is 60% and 48% G+C, respectively, in these regions. The dinucleotide sequence pCG occurs at a higher frequence in both sequences than is normally found in vertebrate DNAs and is approximately 5 times more frequent in the pro-alpha 1 sequence than in the pro-alpha 2 sequence. Nucleotide homology in the helical coding regions is very limited given that these sequences code for the repeating Gly-X-Y tripeptide in a region where X and Y residues are 50% conserved. These differences are clearly reflected in the preferred codon usages of the two mRNAs. PMID- 6927846 TI - Nucleotide sequences of two aspartic acid tRNAs from rat liver and rat ascites hepatoma. AB - The nucleotide sequences of the major tRNAAsp from rat liver and a minor tRNAAsp present specifically in rat ascites hepatoma were determined by combined use of several postlabeling procedures. The sequence of rat liver tRNAAsp was determined to be pU-C-C-U-C-G-U-U-A-G-U-A-phi-A-G-U-G-G-D-G-A-G-U-A-U-C-C-C-C-G-C-U-C-manQ-U C-A -m5C-G-C-G-G-G-A-G-A-m5C-m5C-G-G-G-G-T-phi-C-G-A-U-U-C-C-C-C-G-A-C-G-G-G-G-A G- C-C-AOH. The nucleotide sequence of rat ascites hepatoma TRNAAsp was found to be the same as that of rat liver tRNAAsp, except that mannose-attached queuosine (manQ) present in the wobbling position of rat liver tRNAAsp was replaced by normal guanosine in rat ascites hepatoma tRNAAsp. The other modified nucleosides in the two tRNAAsp species were the same. Thus it was concluded that the new isoacceptor species of tRNAAsp that appears in the tumor tissue is due to hypomodification with respect to Q in the posttranscriptional process. The most notable feature on the sequence of the mammalian tRNAAsp is that cytidine is present in the position next to the 5'-end of the anticodon, because the only known tRNAs having cytidine in this position are cytoplasmic initiator tRNAs from multicellular eukaryotic organisms. PMID- 6927847 TI - DNA sequence for the T7 RNA polymerase promoter for T7 RNA species II. PMID- 6927848 TI - Nucleotide sequence of the influenza A/duck/Alberta/60/76 virus NS RNA: conservation of the NS1/NS2 overlapping gene structure in a divergent influenza virus RNA segment. PMID- 6927849 TI - Promoters and heterogeneous 5' termini of the messenger RNAs of adenovirus serotype 2. PMID- 6927850 TI - Characterization of the structural gene and putative 5'-regulatory sequences for human proopiomelanocortin. PMID- 6927851 TI - Point mutations during generation of expression-linked extra copy of trypanosome surface glycoprotein gene. PMID- 6927854 TI - Sequence at both termini of the 10 genes of reovirus serotype 3 (strain Dearing). PMID- 6927852 TI - A new family of interspersed repetitive DNA sequences in the mouse genome. PMID- 6927853 TI - Sequence variation at the 3' end of the neuraminidase gene from 39 influenza type A viruses. PMID- 6927855 TI - Cucumber mosaic virus RNA 3. Determination of the nucleotide sequence provides the amino acid sequences of protein 3A and viral coat protein. AB - The complete sequence of the 2193 residues of RNA 3 (Mr 746000) of cucumber mosaic virus (Q strain) was determined by a combination of chemical and enzymic sequencing techniques utilizing cloned DNA fragments. The nucleotide sequence of RNA 3 also gave the complete sequence of 1027 residues of RNA 4 (Mr 349000), which codes for the viral coat protein and is derived from the 3' end; there are 53 untranslated nucleotides at the 5' end of RNA 4. The nucleotide sequence provided the amino acid sequences of the two proteins coded for by RNA 3: the 5' terminal 3A protein with 333 amino acids (Mr 36700) and the 3'-terminal viral coat protein with 236 amino acids (Mr 26200). These two coding regions are in the same reading frame, are separated by an intercistronic region of 123 nucleotides and are flanked by two untranslated regions of 94 nucleotides at the 5' terminus and of 263 nucleotides at the 3' terminus. Secondary structure models are postulated for parts of the RNA 3 sequence. These are considered to be important in the control of the translation and replication of RNA 3 and in the processing of RNA 3 to give RNA 4. PMID- 6927856 TI - The sequences of an expressed rat alpha-tubulin gene and a pseudogene with an inserted repetitive element. AB - The rat genome contains two segments closely related to a rat alpha-tubulin mRNA. Both have been cloned and complete nucleotide sequences are presented. Analysis of the structure and sequence of one of these establishes it as a functional alpha-tubulin gene. The second segment is a processed alpha-tubulin pseudogene. Comparison of this pseudogene to the mRNA and gene coding for alpha-tubulin strongly suggests that a mature mRNA was involved in its origin. Features of the pseudogene and a dispersed repetitive element inserted within it possibly reflect a common RNA-mediated process of insertion. PMID- 6927857 TI - Determination of airborne 1,6-hexamethylene diisocyanate by gas chromatography. PMID- 6927858 TI - Atypical dental resorption of permanent teeth. PMID- 6927860 TI - Semantiquated. PMID- 6927859 TI - The role of the area dental officer. PMID- 6927861 TI - A newly designed root canal filling material. PMID- 6927862 TI - Effect of xylitol-supplemented diets on the progression and regression of fissure caries in the albino rat. PMID- 6927865 TI - Histopathological appearance of caries-like lesions of enamel created artificially in vitro in acidified gels containing fluoride. PMID- 6927866 TI - Histopathological appearance of artificially produced caries-like lesions of enamel treated with APF during lesion formation in vitro. PMID- 6927864 TI - Enhancement of fluoride effectiveness by experimental cariogenic priming of human enamel. PMID- 6927863 TI - Inhibition by sodium fluoride of 3H-glycerol incorporation into lipoteichoic acid in Streptococcus mutans. PMID- 6927867 TI - Rate of fluorine uptake by surface and subsurface sound enamel from sodium monofluorophosphate. PMID- 6927868 TI - Increased smooth-surface caries incidence in gnotobiotic rats immunized with Actinomyces viscosus. PMID- 6927869 TI - Accreditation problems: documentation of CPR training. PMID- 6927870 TI - Choice of post-graduation employment by dental students in 1978-79 and the relation to financial indebtedness. PMID- 6927873 TI - Nutrition workshop-conference focuses on caries, dietary control. PMID- 6927871 TI - Whatever happened to leadership? PMID- 6927872 TI - Federally funded dental care. PMID- 6927874 TI - Diet counseling aid to prevention, dental scientist advises. PMID- 6927875 TI - Indiana dental students, faculty stage 'Dr. Dental IQ' programs. PMID- 6927876 TI - Antibiotic treatment urgent for medically compromised patient. PMID- 6927877 TI - A question of lineage. PMID- 6927878 TI - Conference discusses quality assurance. PMID- 6927879 TI - A solution looking for problems? PMID- 6927880 TI - Holocaust in Cambodia; refuge in America. PMID- 6927881 TI - Public opinion and the counterfeit consensus. PMID- 6927882 TI - Dentistry--who's at the controls? PMID- 6927883 TI - Sugar and fluoride content of various forms of tobacco. AB - Previous studies have produced conflicting reports about the possible relationship between the chewing and smoking of tobacco and the incidence of caries. This study identifies the total sugar and the fluoride concentrations of various forms of tobacco from different areas of the United States. This is the first part of an investigation of caries-promoting and caries-inhibiting substances in commercial tobacco products. The total sugar content of pouch and plug forms of tobacco was, on the average, highest, followed by decreasing concentration in the pipe, cigarette, cigar, and snuff forms of tobacco. Fluoride content of the plug and pouch forms of tobacco was highest, followed by cigar, snuff, pipe, and cigarette tobacco, respectively. Generally, nonsmoking forms of tobacco are most directly related to the potential promotion of caries. The total sugar content in the control tobacco leaves was comparable to that in cigars and snuff which have the least amount of sugar, whereas the fluoride content was similar to plug and pouch which have the highest amount of fluoride. Brands of snuff on average had the lowest concentrations of sugar (average 1.9%) and were among the products with the lowest fluoride content (average 0.26 ppm). Pouch and plug exceeded other forms in both sugar and fluoride content. Large variations in sugar and fluoride levels of tobacco products can exist form-to-form, store-to store, brand-to-brand, and state-to-state. This may explain the diverse opinions of dental practitioners and investigators relative to the concept that tobacco increases or decreases dental caries. PMID- 6927884 TI - Evaluation of acetaminophen and aspirin in the relief of preoperative dental pain. AB - The effectiveness of nonprescription analgesics--acetaminophen and aspirin--in providing subjective relief of preoperative dental pain was evaluated in a varied population of adults. This study demonstrates for the first time the feasibility of evaluating preoperative analgesic efficacy in preoperative dental pain and provides evidence that acetaminophen (1 gm) and aspirin (1 gm) can alleviate dental pain better than a placebo. PMID- 6927885 TI - Copper-rich and conventional amalgam restorations after clinical use. AB - The comparison of clinically retrieved conventional and copper-rich amalgam restorations demonstrated that there are at least two distinct types of compounds that form in vivo in amalgam restorations, tin-rich layers on the exposed surface of many amalgams and tin-chlorine and smaller amounts of stannous oxide products in the interior. In the systems rich in copper, corrosion was confined to the surface and a few isolated areas. The relatively small changes found in the systems rich in copper could account for the superior marginal integrity reported for copper-rich amalgams in clinical trials. PMID- 6927886 TI - Prepubertal oral pemphigus vulgaris. AB - Although rare, oral pemphigus vulgaris must be considered in those patients who have a prolonged history of oral lesions. The fact that chronic oral lesions characteristically precede skin changes in pemphigus emphasizes the importance of this disease to the dental profession. Patients with long-term and recurrent vesiculoulcerative oral lesions should undergo biopsy examination to establish the diagnosis. The dentist and the physician must collaborate to establish an appropriate diagnostic and therapeutic plan for the management of these patients. PMID- 6927887 TI - Bilateral congenital facial paralysis. AB - A 17-year-old girl who has the Mobius syndrome showed compensatory motions in sucking, speech, and eating. Movements of facial expression were absent (except for contraction of the buccinator muscle and some closure of the eyelids). The patient has been referred to a specialist for restoration of additional facial expression. PMID- 6927890 TI - Elastic tissue in early intraoral wounds. AB - Histochemical analysis of elastic tissue in early intraoral healing of wounds demonstrated that these fibers were concentrated in the perivascular areas of granulation tissue and within newly formed connective tissues at the base of the wound. These results were consistent with previous reports indicating that the cellular origin of this tissue is smooth muscle cells or fibroblasts. PMID- 6927888 TI - Summary of symposium on dental perspectives--International Year of the Child. AB - Children's dental health needs, an oral health index, the importance of communal fluoridation, and manpower distribution were discussed. PMID- 6927889 TI - Home care utilizing a ventilator in a patient with amyotrophic lateral sclerosis. AB - A patient with respiratory neuromuscular paralysis secondary to amyotrophic lateral sclerosis is described who was managed at home for more than 12 months on a volume cycled respirator. Although the cost is high, it is less than in an acute care hospital setting. Requirements for success include parient selection, adequate home environment, and dedicated medical and paramedical personnel. PMID- 6927891 TI - Hypothalamic-pituitary-adrenal suppression after short-term dexamethasone therapy for oral surgical procedures. AB - Ten patients were given dexamethasone therapy for prevention of postoperative complications after oral surgical procedures. The hypothalamic-pituitary-adrenal response of the patients was measured by their response to a single-dose metyrapone test. A significant difference was found between preoperative values of 11-deoxycortisol and values three days postoperatively. No difference was found when comparing preoperative values of 11-deoxycortisol with values seven days postoperatively. There appears to be an initial suppression of the normal feedback mechanism of the hypothalamic-pituitary-adrenal axis followed by a complete return of normal functioning by the seventh postoperative day. The amount of surgical stress involved in these routine oral surgical procedures is of an insufficient magnitude to overcome this hypothalamic-pituitary-adrenal suppression of the negative feedback mechanism caused by dexamethasone therapy. The presence of adequate amounts of synthetic steroids at a cellular level appears to prevent manifestations of adrenal insufficiency despite suppression of endogenous production of steroids. PMID- 6927892 TI - The ilium as a source of autogenous bone for grafting: clinical considerations. AB - The surgical anatomy and morbidity associated with ilium surgery for the obtaining of bone graft material have been presented. A recommended surgical approach has been introduced, and the advantages and disadvantages of this technique and others are discussed. PMID- 6927893 TI - Treatment of mandibular fractures by intraoral placement of bone plates. AB - We have used bone plates in the treatment of mandibular fractures for the past 12 years. In carefully selected cases, this procedure can obviate the need for dental fixation in young and active patients, or in patients with multiple injuries. PMID- 6927894 TI - Decortication and bone replacement technique for the treatment of a large mandibular cyst. AB - A large odontogenic keratocyst associated with an impacted canine and an odontoma, has been reported. The surgical technique described may be helpful in treating other benign pathologic lesions. It provides access to medullary bone for biopsy and to the tooth buds and the neurovascular bundles for repositioning procedures. Support of the vestibular flap and early osseous repair are clinically evident. Early detection and treatment of disease in this patient would have prevented extensive bone destruction and thus eliminated the need for this type of surgical technique. PMID- 6927895 TI - Conservative treatment of bilateral persistent anterior dislocation of the mandible. AB - Protracted anterior dislocation of the mandible was successfully treated by a conservative method without recurrence after a year. PMID- 6927896 TI - Solitary keratoacanthoma of the lip. PMID- 6927897 TI - Mucoepidermoid carcinoma in the mandible: report of case. AB - Mucoepidermoid carcinoma, a salivary gland tumor arising centrally within the jaws, is rare. The literature concerning this tumor has been reviewed. Diagnosis and treatment of a case in 44-year-old man has been presented. PMID- 6927898 TI - Trichilemmoma of the lip: report of case. AB - A case of trichilemmoma of the upper lip has been presented and the entity is discussed. This particular case, similar to so many others reviewed in the literature, was mistaken for a basal cell carcinoma or verruca. PMID- 6927899 TI - Surgical placement of a chin cleft concomitant with genioplasty. AB - This article presents a surgical technique for creation of a chin cleft in conjuction with advancement genioplasty. The technique is simple. However, the cleft should be made deeper than seems aesthetically desirable at the time of surgery because healing and muscle function will decrease the final depth of the depression. The depth that can be anticipated can be determined by the degree of tension of the subcutaneous sutures. Minor recontouring of bone may be necessary when there is a prominent bony apex to the symphysis. The actual chin cleft is a soft tissue phenomenon, rather than a bone cleavage point. It is not suggested that this procedure be offered to every patient, but familiarity with the technique is needed should there be a request to perform such surgery. PMID- 6927902 TI - Alternative forms of dental care: a challenge to private practice. PMID- 6927901 TI - Gigantiform cementoma: report of two cases (mother and son). PMID- 6927900 TI - A simplified stent for palatal surgery. PMID- 6927903 TI - Attitudes of dentists in British Columbia toward removable prosthodontics. PMID- 6927904 TI - Prerestorative therapy using a modified Hawley splint. PMID- 6927905 TI - Reinforcement of porcelain crowns with silicon carbide fibers. AB - A method to reinforce dental porcelain with silicon carbide fibers was presented. The results indicated that an increase in fracture strength is possible with dental porcelain containing silicon carbide fibers. However, further investigations are needed to create a practical method for strengthening porcelain jacket crowns. PMID- 6927906 TI - The cutting effectiveness of carbide fissure burs on teeth. AB - The cutting effectiveness of the burs decreased with time. While the multivariate analysis of variance showed an overall difference among the three groups, these differences appeared to be due to the shape of the curves (the linear and quadratic components) rather than to their average location (the mean). Therefore there were no significant differences in cutting among the three types of burs tested. The SEM photomicrographs showed that there was no gross bur damage after the burs were used for cutting tooth structure. The cutting mechanism of a carbide bur on tooth structure needs further investigation. PMID- 6927907 TI - Frozen-slab technique for mixing zinc phosphate cement for cast restorations. AB - The technique for handling zinc phosphate cement can be altered to achieve enhanced properties of the cement. The compressive strength of the material can be decreased. The film thickness can be maintained within acceptable limits, and the possibility of pulpal damage can be kept low by maintaining temperature changes in the cement similar to those obtained from a room temperature-slab technique. The technique advocated by this report is as follows: 1. Store the aluminum slab with vinyl covering in a freezer at -15 degrees C to -20 degrees C in a plastic bag to prevent ice formation on the surface. 2. Remove the slab when ready to mix. 3. Quickly wipe the slab clean. 4. Dispense twice as much powder and liquid as recommended on the slab. 5. Start timer. 6. Slowly incorporate the powder into the liquid over a large area of the slab for 2 minutes. 7. Allow the mix to remain on the slab. 8. The instrument for placing the cement can be placed under the slab. The casting can be placed on a corner of the slab. 9. At 10 minutes, place the cement into the casting(s) and seat. 10. Remove excess cement. 11. Clean the slab by rinsing in water and gently wiping. 12. Dry the slab, place it in the plastic bag, and return it to the freezer. PMID- 6927910 TI - Surgical nasal prosthesis. AB - This method of fabrication of an immediate nasal prosthesis has distinct advantages which recommend its use. These are (1) the use of an RTV silicone rubber impression as the refractory cast cuts fabrication time to minutes rather than hours, as compared with other methods of fabricating a nasal prosthesis; (2) the RTV silicone is permanent and stable and provides an exact reproduction of the part to be excised; (3) the initial RTV silicone impression may be used during fabrication of the definitive prosthesis as the mold for production of a wax sculpting model; (4) PVC prostheses offer a unique advantage of being soft enough for trimming with scissors at the time of surgery and are flexible and tissue-compatible; and (5) psychological trauma is minimized and the patient is better prepared for a definitive prosthetic restoration. PMID- 6927909 TI - The etiology, diagnosis, and treatment of TMJ dysfunction-pain syndrome. Part II: Differential diagnosis. AB - Differential diagnosis is based on the pain history in combination with the clinical findings of muscle spasm and occlusion in relation to the condylar displacement as observed in the TMJ radiographs. Most often TMJ dysfunction-pain syndrome produces symptoms that have a pattern of occurrence or can be associated with function. Neurologic, vascular, and conversion pain occur at random without a pattern of occurrence and with no relation to function. Atypical TMJ dysfunction pain can occur by itself or in combination with other unrelated pain causes. Differential diagnosis is usually aided by injections of local anesthetics and diagnostic trials of an anterior bite plate and relaxant drugs. Medical consultation is advised when a diagnosis of TMJ dysfunction-pain syndrome cannot be established. Hysterical conversion is extremely rare, although occasionally a patient may have pain of unknown origin. PMID- 6927908 TI - The fracture strength of amalgam overlying base materials. AB - Conclusions reached within the constraints of this study showed the following: 1. Fracture strength of Class II amalgam restorations decreased as the thickness of the bases increased. 2. Fracture strengths of amalgam restorations based with different thicknesses of zinc phosphate cement underline with 0.5 mm Dycal were not different from each other. 3. The strength of the restorations varied with the type of base. Zinc phosphate cement is equal to no base and superior to zinc phosphate cement plus Dycal, which is equal to Dycal. Dycal is superior to Cavitec, which is the same as Cavitec plus Dycal. 4. The base materials did not fracture. The amalgam restorations were stronger over a base with a higher modulus of elasticity, indicating that modulus of elasticity of a base is more important than compressive strength in supporting an amalgam restoration. 5. There is no advantage (no improvement in resistance to fracture of the amalgam restoration) to be gained from placing zinc phosphate cement over Dycal. 6. When a calcium hydroxide liner is not needed, the cements with a higher modulus of elasticity, such as zinc phosphate cement and reinforced ZOE, will provide for stronger amalgam restorations than Cavitec and unreinforced ZOE. PMID- 6927911 TI - Accetability of orbital prostheses. AB - This study was made to determine if those patients apparently dissatisfied with an orbital prosthesis might accept an eye patch more readily. The study included 27 patients who were seen during the past 8 years. A total of 60 orbital and eye patch proshteses were prepared for the patients. Eighteen patients responded to the questionnaire. Twelve of these patients are presently wearing their prostheses, and five of them are not. Reasons given by the patients for not using their prostheses were discomfort, lack of retention, skin irritation due to daily application and removal of the adhesive, change in defect, ill-fitting prostheses, and surgical reconstruction of the site. The study shows that given a choice, 67% of the patients would prefer the orbital prosthesis. Seventy-five percent of the patients who had an eye patch would prefer an orbital prosthesis. PMID- 6927912 TI - A cephalometric study of mandibular cortical bone thickness in dentulous persons and denture wearers. AB - Cephalometric measurements of the cortical thickness of the inferior mandibular border and the inferior aspect of the mandibular symphysis were compared in two groups of subjects, one with complete dentition and the other wearing complete maxillary and mandibular dentures. Although the cortical thickness of the inferior mandibular border increased slightly with age in both dentition groups, the cortical thickness was significantly less in denture groups than in their respective dentition groups. The opposite was true with the cortical thickness of the inferior aspect of the mandibular symphysis; a decrease in thickness was noted with age, and a slight increase in thickness was noted with edentulousness. The results suggest that bone remodeling can be expected at sites distant from the residual ridge in denture wearers. PMID- 6927913 TI - Flexural properties of denture base polymers. AB - Heat-polymerized denture base materials with the cross-linking agent 1,4-BDMA and with different amounts of the cross-linking agent EGDMA have similar flexural properties. At the relatively low loading rate of 2 N/minute all the heat polymerized denture base materials investigated have better flexural properties than the autopolymerized pour- and dough-type materials. The autopolymerized materials with the cross-linking agent 1,4-BDMA have flexural properties intermediate to the heat-polymerized and the autopolymerized resins with the cross-linking agent EGDMA. The various autopolymerized resins behave differently, probably due to varying amounts of pendant methacrylate groups. Due to so-called solvent crazing, denture base polymers have poorer flexural properties when tested in water than in air. PMID- 6927916 TI - Physostigmine in Gilles de la Tourette's syndrome. PMID- 6927915 TI - Polymorphism of DNA sequence in the beta-globin gene region. Application to prenatal diagnosis of beta 0 thalassemia in Sardinia. AB - We used a restriction endonuclease to analyze the beta-thalassemia gene in Sardinia. When we digested human DNA with the restriction enzyme Bam HI, the beta globin gene split into a 5' portion contained in a fragment of DNA 1.8 kb in length and a 3' portion in a fragment 9.3 kb in length. In some subjects, a variation in the nucleotide sequence affecting the site recognized by this enzyme on the 3' side of the beta-globin gene resulted in a different fragment, 22 kb in length, which contained the 3' portion of the beta-globin gene. In Sardinians without beta-thalassemia, the frequency of the 9.3-kb fragment was 0.67, and that of the 22-kb fragment was 0.33. In contrast, all the beta 0-thalassemia genes were associated exclusively with the 9.3-kb fragment. Thus, the beta 0 thalassemia lesion in Sardinians apparently arose on a chromosome that had the 9.3-kb Bam HI fragment. This observation can be used in prenatal diagnosis of beta 0-thalassemia in Sardina, since demonstration of the 22.0-kb fragment would indicate the normal beta-globin genotype and exclude the beta 0-thalassemia lesion on that chromosome. (N Engl J Med 302:185-188, 1980). PMID- 6927917 TI - Patenting living organisms--how to beat the bug-rustlers. PMID- 6927914 TI - Leukemia after therapy with methyl CCNU. PMID- 6927918 TI - Ad in and ad out. PMID- 6927920 TI - Radiation free report. PMID- 6927919 TI - Dental journalism. PMID- 6927921 TI - 3 dental bills pass Senate and Assembly. PMID- 6927922 TI - ADA acts on heavy agenda at Dallas meeting. PMID- 6927923 TI - Desquamative gingivitis. PMID- 6927924 TI - DSSNY objects to FTC recommendation re elimination of state's licensure prerogative. PMID- 6927926 TI - Liability insurance losses force premium increase. PMID- 6927925 TI - DSSNY strives to amend truth in testing law. PMID- 6927928 TI - Median palatal cyst--report of a case of unusual size. PMID- 6927927 TI - The dental practitioner and his role in the reconstructive management of the cancer patient. PMID- 6927929 TI - Oral soft-tissue examination by dental hygienists. PMID- 6927930 TI - Access, institutional advertising--to preserve private practice. PMID- 6927931 TI - The multicentric nature of oral carcinoma. PMID- 6927932 TI - Communication lines must be kept open. PMID- 6927933 TI - Cryosurgery used in treatment of gland malignancy. PMID- 6927935 TI - Board of Governors to monitor closely ADA's pilot ad program in Buffalo. PMID- 6927934 TI - Emergency treatment for ingestion of large amounts of fluorides. PMID- 6927936 TI - Rotational therapy with a colchicine analog in chronic granulocytic leukemia. AB - 9 patients with chronic granulocytic leukemia were treated sequentially with busulfan, 6-mercaptopurine, and trimethylcolchicinic acid methyl ether d-tartrate (TMCA; NSC-36354). Smoothness of control of the disease was similar with busulfan and 6-mercaptopurine, but it was significantly poorer with TMCA. Toxic effects of therapy and median survival were similar to those observed with conventional therapy. PMID- 6927937 TI - Oral amyloidosis as initial symptom of multiple myeloma. A case report. AB - A case of multiple myeloma has been presented where intraoral amyloidosis was the presenting symptom associated with the disease. Definitive diagnosis was based on the findings of hyperglobulinemia, marrow aspiration showing plasma-cell infiltration, proteinuria, amyloidosis, and anemia. PMID- 6927938 TI - Hemifacial microsomia: an anesthetic airway problem. AB - Hemifacial microsomia is a rare congenitally acquired dentofacial deformity characterized by unilateral hypoplasia of the hard and soft tissues of the face and cranium. Associated anomalies of the vertebrae and hypopharynx cause perioperative airway management to be difficult. The case of a patient with severe heimfacial microsomia, cervical spine fusion, and temporomandibular joint ankylosis is presented, with special emphasis on anesthetic airway management. A device to aid fiberoptic nasolaryngoscopy when difficult endotracheal intubations are encountered is described. PMID- 6927939 TI - Oral cytologic patterns and nutritional status: some relationships in alcoholic subjects. AB - Exfoliative cytologic preparations from the cheeks of 790 alcoholic patients were evaluated for relationships between microscopic features and selected indicators of nutritional status. Significant associations were observed between the cell/nucleus ratio, degree of cornification, relative concentrations of leukocytes and microorganisms, and poor dietary patterns, as well as body weight statua and serum albumin and blood hemoglobin levels. Microscopic examination, as an adjunct to gross inspection of the mouth, may be of value in the clinical assessment of nutriture. PMID- 6927941 TI - Pigmented nevi of the oral mucosa: a clinicopathologic study of 32 new cases and review of 75 cases from the literature. Part II. Analysis of 107 cases. AB - Review and analysis of data of seventy-five cases from the literature, together with an additional thirty-two new cases, revealed that nevi of the oral mucosa are not rare and may be more common than previously thought. Nevi of the intramucosal type are the most common, followed by the common blue nevus. Compound nevi are uncommon, and junctional nevi are very rare. The data are analyzed as to the location, presence of clinical pigmentation, configuration, size, and duration of the nevi, as well as the patient's age, sex, and race. Oral nevi (especially those that are clinically nonpigmented) are often misdiagnosed, indicating that they are far more common than they would seem from the reported cases. The potential for oral nevi to undergo malignant transformation is unclear because of the paucity of cases and limited follow-up. Nevertheless, we recommend that all oral pigmented nevi be removed. PMID- 6927940 TI - Painful dysphagia due to fracture of the styloid process. AB - Pain in the neck region following trauma to the mandible can be caused by styloid process fracture. This is usually the result of pressure on the glossopharyngeal nerve as it crosses the gap between this process and the first cervical vertebra. The following paper discusses two case reports of patients who developed painful dysphagia as a result of this type of trauma. PMID- 6927943 TI - Occurrence of microorganisms at different levels of the pulp. Contribution to endodontic techniques. AB - Microorganisms were absent in the remaining pulp stumps of twenty teeth which had been exposed to caries and contaminated at the pulpal chamber level. We have demonstrated that microorganisms are not carried to the deepest areas of the pulp when the basic procedure is strict antisepsis applied to the living pulp stump. A sterile and living pulp stump wound contributes to an adequate biologic sealing of the apical foramen. Of all the isolated microorganisms, the alpha hemolytic Streptococcus was most frequently found in all examined cases, in pure or mixed cultures, demonstrating once again he prodominance of that type of microorganism when pulpal injury occurs. PMID- 6927944 TI - Ultrasonic versus hand filing of dentin: a quantitative study. AB - Ultrasonic versus hand-powered K type files were compared for their ability to remove dentin from a standardized canal. The ultrasonic energized file removed a significantly greater amount of dentin in a fixed time period. PMID- 6927942 TI - Treatment and prognosis of diffuse sclerosing osteomyelitis (DSO) of the mandible. AB - Twenty-one patients with diffuse sclerosing osteomyelitis (DSO) of the mandible were investigated and treated in Goteborg. Sixteen of these patients ( twelve women and four men) participated in a long-term follow-up study in order to evaluate different therapeutic procedures. Cortisone was found to be a valuable aid to the therapy arsenal. Clinical and radiographic observations are presented. Etiology, therapy, and prognosis of DSO are discussed. PMID- 6927945 TI - Evaluation of 5,000 endodontic treatments: incidence of the opened tooth. AB - Five thousand endodontic cases treated by three endodontists were reviewed to determine the frequency of the need to leave teeth opened for drainage. The subsequent treatment of these teeth is described. Of the 5,000 cases reviewed, 518 were left open at some point during treatment. Two hundred and eighty-one cases (54.2 percent) remained closed after the first closure. Four hundred and twenty-six (82.2 percent) of the cases opened were eventually completed without surgical intervention. The need to prescribe antibiotics and perform a trephination is also stated. PMID- 6927947 TI - Anatomy of mandibular third molars. A comparison between radiographic appearance and clinical observations. AB - The purpose of this study was to present a radiographic technique for the examination of mandibular third molars and to investigate the extent of correspondence between the radiographic appearance and the true anatomy of the tooth. Forty-four mandibular third molars were examined radiographically and subsequently removed. The investigation showed that radiographic examination of mandibular third molars, utilizing intraoral films in three different projections, gave an insight into the true anatomy of the tooth. The few instances of minor misinterpretation could be grouped into two categories: (1) root dilacerations which paralleled the direction of the beam were not always apparent on the radiographs; and (2) the degree of fusion between roots lying close together was not usually well defined on the radiographs. PMID- 6927946 TI - What's the angle: a study of the angle bisected in intraoral radiography. AB - Intraoral radiographs were made via the bisecting-the-angle technique on patients of different ages, sexes, and races. The tooth-film angles for various areas of the mouth were measured and found to be close to 30 degrees for all areas of the mouth except the mandibular posterior regions. The study was conducted to assist in quick positioning of the x-ray beam in difficult cases. PMID- 6927948 TI - Impaction of a mandibular first permanent molar. PMID- 6927950 TI - Transposition of the permanent mandibular canine. PMID- 6927949 TI - Exfoliated odontoma. PMID- 6927951 TI - Skeletal osteosarcoma. Animal model: canine osteosarcoma. PMID- 6927952 TI - A possible hazard with use of the Ohio Ethrane vaporizer. PMID- 6927953 TI - Acute myelogenous leukemia and hepatitis. PMID- 6927954 TI - Micro-hardness characteristics of anterior restorative materials. PMID- 6927955 TI - Something you might have missed: increased National Insurance charges for 1980/81. PMID- 6927956 TI - Combination chemotherapy for terminal-phase chronic granulocytic leukemia: cancer and leukemia group B studies. AB - A 34% response was obtained in 202 evaluable patients in the terminal phase of chronic granulocytic leukemia using combinations of hydroxyurea, 6 mercaptopurine, and corticosteroids. Twelve percent of responses were complete and 22% partial. Overall median survival was 12 wk. A 30 wk median survival for responding patients was statistically superior to the 7-wk survival for nonresponders (p less than 0.001). Response was inversely correlated with toxicity. No responses were obtained in patients sustaining both severe infectious and bleeding complications. No benefit could be demonstrated from the addition of vincristine in induction and daunorubicin for consolidation. Although the response frequency and duration of survival with this combination chemotherapy were generally superior to those previously reported by our group, the terminal phase of chronic granulocytic leukemia still remains a formidable and generally refractory disease. PMID- 6927957 TI - Acute monoblastic leukemia: a clinical and biologic study of 74 cases. AB - Seventy-four cases of pure acute monoblastic leukemia (AMol) have been retrospectively studied. All patients were treated at Hospital Saint-Louis between 1970 and 1978. Diagnosis was based on morphological and cytochemical features according to the FAB classification. This type of leukemia occurred at any age and in both sexes, with a high frequency of extramedullary involvements. Hyperleukocytosis was very frequent and was significantly correlated with increased blood and urine levels of lysozyme, with renal failure and hypokalemia, and with coagulation abnormalities. AMol still has a poor prognosis, despite a best remission rate (75%) obtained with rubidazone, since the duration of complete remission was short. Central nervous irradiation prolonged remission and prevented meningeal relapses, while 6 meningeal relapses occurred in the patients not irradiated. The high frequency of the extramedullary relapses, including gum and skin, emphasized the question of persistant blast cell sanctuaries after achievement of bone marrow remissions. A more intensive induction with several drugs active against monoblasts could be more efficient and prolong the duration of complete remissions. PMID- 6927958 TI - Central nervous system recurrence ten years after remission of acute lymphoblastic leukemia. AB - Therapy with vincristine and prednisone achieved a complete remission in a 10 year-old Caucasian girl with acute lymphoblastic leukemia. Maintenance therapy with 6-mercaptopurine was then administered for seven years, but prophylactic intrathecal chemotherapy and central nervous system (CNS) radiation were never given the patient. Ten years from the time of diagnosis, she presented with signs of increased intracranial pressure and a diagnosis of CNS leukemia was confirmed. At this time, however, no leukemia was detected on examination of her blood and bone marrow. She was successfully treated with intrathecal methotrexate and radiation therapy. After a careful search of the literature it has been concluded that this is the first reported case of such a long remission of acute lymphoblastic leukemia with subsequent relapse. PMID- 6927959 TI - Osteogenic sarcoma: a study of the ultrastructure. AB - Ultrastructural examination of 26 osteogenic sarcomas has revealed that in addition to the basic osteoblast comprising the tumor, five additional cell types may be identified. These include chondroblasts, osteocytes, undifferentiated cells and myofibroblasts. The latter cell type has not been reported in previous studies of medullary osteosarcomas. The relative portions of the cell types varied as to the type of osteogenic sarcoma studied. Osteoid production, the single diagnostic feature of these tumors, was evident and the various ultrastructural appearances of this material are shown. One case of an osteogenic sarcoma that arose in Paget's disease of bone is described and did not differ ultrastructurally from the conventional medullary osteogenic sarcoma. Our studies have shown that osteogenic sarcoma may share common ultrastructural features with other sarcomas involving bone and soft tissue and that the basic difference between osteogenic sarcoma and soft-tissue sarcomas is the presence of osteoid in the former and differing cytoplasmic differentiation in the latter category of tumors. PMID- 6927960 TI - A case of AMMoL with 8/21 translocation and loss of the Y as probably secondary events. AB - The clinical, hematological, and cytogenetic characteristics of a male patient with AMMoL are described. Before treatment a clone with the complex karyotype 45,X,del(7)(q32), t(8;21)(q22;q22) was present in the bone marrow. During partial remission induced by cytostatics, the percentage of normal cells increased, and a cell line having a 46,XY,del(7)(q32) karyotype was found. After four therapy courses, when remission was complete, only chromosomally normal cells were seen. The cytogenetic data suggest that in this case the 8/21 translocation and loss of the Y chromosome were only secondary events. PMID- 6927962 TI - Procollagens as markers for the cell of origin of human bone tumors. AB - Cells derived from osteogenic sarcomas and from Ewing's sarcomas, two malignant bone tumors, were examined for the types of collagens they elaborated into the tissue culture media. Type I procollagen was the predominant species from all osteogenic sarcoma cell lines, a finding consistent with bone cell origin. The Ewing's sarcoma cells contained a prominent peak of type III procollagen and resembled the profile of vascular smooth muscle cells. Fibroblasts derived from skin biopsies taken from amputation specimens synthesized both type I and type III procollagens at the expected ratio of approximately 3:1. The examination of matrix proteins may provide a general classification scheme for human sarcomas and permit distinction of one tumor from another, as well as from normal fibroblasts. PMID- 6927963 TI - In vivo uptake and retention of fluoride in human surface enamel after application of a fluoride-containing lacquer (fluor protector). PMID- 6927964 TI - Calorimetric studies of the interaction between hydroxyapatite and certain anions in aqueous solution. PMID- 6927965 TI - Penetration of fluorine from sodium monofluorophosphate into artificially produced incipient enamel lesions. PMID- 6927966 TI - Cariogenicity of disaccharide alcohols in rats. PMID- 6927968 TI - Effect of flossing, with and without iodine, on human interproximal plaque flora. PMID- 6927961 TI - Systemic mycosis due to Trichosporon cutaneum: a report of two additional cases. AB - Two additional cases of systemic mycosis due to Trichosporon cutaneum are reported and are compared with the previously published case of Rivera and Cangir. Both patients (a four-year-old male and a 57-year-old female) had acute leukemia for which they were receiving chemotherapy, and both presented with fever that was unresponsive to conventional antibiotics. Both had positive blood cultures for Trichosporon cutaneum. The disease was further documented in the four-year-old male by renal biopsy and by bone marrow culture; he was treated with apparent success with amphotericin B. However, the 57-year-old female died shortly after the begining of similar treatment, and autopsy demonstrated involvement of the left kidney, spleen, bone marrow, and liver. The organism in both these cases, as well as the case of Rivera and Cangir, exhibited both hyphal and yeastlike forms in tissue sections. We believe that the therapeutic success in the case of the four-year-old male was primarily related to his remission from leukemia. PMID- 6927970 TI - A nondestructive method for monitoring de- and remineralization of enamel. PMID- 6927969 TI - Effects of chlorhexidine dihydrochloride in the diet on caries in hamsters. PMID- 6927971 TI - Absorption of fluoride from fluoride dentifrices. PMID- 6927972 TI - [Leukoplakia]. PMID- 6927967 TI - Contribution of maltitol and lycasin to experimental enamel demineralization in the human mouth. PMID- 6927973 TI - [Longitudinal study of gums and teeth during pregnancy]. PMID- 6927974 TI - [Basic elements of light wire technic]. PMID- 6927977 TI - Accreditation problems: recent data show trends. PMID- 6927975 TI - [Properties of carboxylate cement (a review of the literature)]. PMID- 6927976 TI - [The average number of occluding points in wearers of full dentures]. PMID- 6927978 TI - In vitro augmentation of cytotoxicity against tumor cell lines by mumps virus. AB - Cultures of leukocytes from normal subjects and bladder and kidney cancer patients contain cells cytotoxic against various tissue culture human cell lines. Postculture cytotoxicity was increased, in some experiments, after cocultivation with an inactivated strain of mumps virus. Effector cells seem to have an Fc receptor inasmuch as the activity was removed by absorption on immoblized antigen antibody complexes. PMID- 6927979 TI - Parosteal (juxtacortical) osteosarcoma. A clinical and histopathological study of 11 cases and a review of the literature. AB - At re-examination of all osteosarcomata recorded in the Swedish Cancer Registry during the years 1958 to 1968, 11 cases of parosteal osteosarcoma were found. No case of so-called periosteal osteosarcoma was identified. The tumours constituted 1.6 per cent of all proved primary malignant bone tumours. The ages of the 11 patients (six women and five men) ranged from 17 to 62 years (average 33 years). The clinical and histopathological findings of this study and of those collected from a review of the literature suggest the occurrence of two different types of parosteal osteosarcoma: the predominant type is originally benign but has a definite malignant potential, causing metastases after long symptom-free intervals; the other type is highly malignant from the beginning. Primary amputation is recommended for the latter category of tumours, and compartmental, radical en bloc resection followed by regular review is recommended for the former. PMID- 6927983 TI - Phase plane modeling of human jaw movement: reproducibility and rhythm dependency of the RMS error. AB - The rhythm dependence and reproducibility of the jaw motion error for open-close clench movements in man have been investigated. The results indicate that the error strongly depends upon the rhythm of movements. Sometimes there is a significant difference (p less than 0.05) between corresponding series of jaw motion errors indicating a lack of reproducibility of the error at a repeat test. PMID- 6927981 TI - Gingival matrix collagen in chronic periodontitis. AB - The isolation and characterization of cyanogen bromide peptides derived from the human gingival collagen of patients with chronic periodontitis revealed the presence of both Type I and Type III collagens in this tissue. The amount of TYPE III collagen, however, was found to be lower than that in normal gingival tissue. In addition, a non-collagenous protein fraction, accounting for approximately 20% of the insoluble matrix, was relatively rich in acidic, hydrophobic, and hydroxy containing amino acids. Amino acid analysis, likewise, revealed qualitative and quantitative differences between the normal and diseased tissues. PMID- 6927980 TI - Multiple-drug chemotherapy for the primary treatment of osteosarcoma of the extremities. AB - Fifty-five cases of osteosarcoma of the extremities were treated between 1972 and 1976 by combined surgery and chemotherapy (vincristine, adriamycin and methotrexate in medium doses) for 18 months. The follow-up ranges from 30 to 80 months (mean = 48 months). Twenty-six patients remained free from any evidence of disease, two had local recurrences but no metastases and 27 had metastases (four of these also had local recurrences). In 12 patients, the metastases appeared after the end of chemotherapy. Both metastases and local recurrences were more frequent in patients who had segmental bone resection (7/8) than in those treated by more radical surgery (22/47). Comparison with an "historical" group (94 osteosarcoma patients treated by operation alone in our Institute between 1960 and 1971) showed that the percentage of patients free from evidence of disease was higher in the group who receiving chemotherapy. In addition, the appearance of metastases in this group was delayed (mean = 16 months) as compared with the historical controls (mean = 8 months). On the other hand, after the same kind of operative treatment, the rate of local recurrences and the time of their appearance was almost identical in both groups. PMID- 6927982 TI - The effect of mouthrinse containing calcium glycerophosphate on the chemical composition and development of plaque in humans. AB - Children rinsed twice daily with one of two concentrations of calcium glycerophosphate or a placebo. Plaque was collected at two-week intervals for eight weeks, and Loe and Silness Indices determined. Results indicate a lower index rating and a higher phosphorus content for experimental groups than for the control at the four-week examination. PMID- 6927984 TI - Zinc oxide eugenol cements. V. Instrumental studies of the catalysis and acceleration of the setting reaction. AB - Zinc oxide eugenol (ZOE) cements were prepared by mixing powders of widely differing reactivity with a variety of liquid formulations. The course of the setting reaction was followed by penetrometer, rheological and electrical techniques. Small amounts of water, organic acids, and the reactivity of water, organic acids, and the reactivity of the zinc oxide all have a profound influence on the setting characteristics of cement pastes. PMID- 6927985 TI - Dynamic mechanical properties of resin-based filling materials. AB - The elastic moduli and mechanical damping of a range of polymeric restorative materials have been determined using a torsion pendulum. Composite materials have high moduli and low damping compared with unfilled resin. These materials have stable mechanical properties, but variation occurred as a result of different specimen conditioning methods. Non-destructive testing was valuable in that it allowed repeated testing of a single specimen. PMID- 6927986 TI - Clinical performance of amalgam as predicted by physical property tests. AB - For a number of years, dentistry has relied upon laboratory data to select and to certify the materials to be used in restorations. The data obtained from laboratory studies are used as criteria for clinical performance and also for sales promotion. PMID- 6927987 TI - Corrosion test for dental amalgam. AB - A corrosion test for dental amalgam, based on controlled potential coulometry, provides an index of corrosion susceptibility. A special cell was designed, and optimum test conditions were determined. The test can be used for the rating of amalgams, and in studies of the effect of variables on the corrosion resistance. PMID- 6927988 TI - Translucency of dental porcelains. AB - The translucency of comparable shades of five dental porcelains was determined. Both direct transmittance and total transmittance were measured at wavelengths of 400-700 nm. For 1 mm of porcelain, the values for direct transmittance were low and averaged 0.13 percent, whereas the values for total transmittance averaged 26.8 percent. Transmittance increased with increasing incident wavelength. These results indicated a high degree of light scattering. PMID- 6927989 TI - Electron microscopic localization of virions in developing teeth of young hamsters infected with minute virus of mice. AB - Virus particles were detected within the nuclei and cytoplasm of odontogenic cells in the developing teeth of young hamsters infected with a small DNA virus (MVM). Disturbances of normal cytodifferentiation and organogenesis occurred as a result of viral multiplication. Virions were also observed in dense lysosome-like bodies of activated monocytes within the periodontal ligament and adjacent connective tissues. Fibrolytic and osteolytic lesions in the periodontal ligament and adjacent alveolar bone were associated with the inflammatory cell infiltrate. PMID- 6927990 TI - Experimentally induced alterations in periapical tissues of the cat. AB - Ten cats were immunized with subcutaneous injections of keyhole limpet hemocyanin (KLH). After it was determined that the experimental animals had developed circulating antibodies to KLH, challenge doses of KLH were administered via the root canal system. The radiographic and histologic findings suggest that antigen antibody complex reactions can occur in periapical tissues of teeth, and that they can play a role in the pathogenesis of periapical lesions. In contrast, no radiographic and histologic changes were noted in non-immunized cats. PMID- 6927992 TI - Effect of clinical finishing procedures on amalgam microstructure. AB - Spherical amalgam specimens were burnished, burnished-polished, polished (wet), or polished (dry). The amalgams were sectioned normal to the prepared surface, elemental analyses were made at a series of depths from the surface with the electron microprobe and the phase fractions were calculated. Significant variations in phase distributions exist within 100 micrometers of the surface. PMID- 6927991 TI - Long term effects of primary molar pulpotomies on succedaneous bicuspids. AB - Forty-three bicuspids which replaced successfully pulpotomized vital or non-vital primary molars, and twenty bicuspids, which erupted following unsuccessful pulpotomies requiring extraction of the preceding teeth, were examined for defects of position and enamel. In comparison with contralateral control teeth, test teeth in both groups showed an increased prevalence of rotation and enamel surface defects. PMID- 6927994 TI - Scanning electron microscopic observations of the selective habitation of bacteria on the lingual mandibular gingiva of the rat. PMID- 6927993 TI - Ultrastructure of a presumptive Golgi-Mazzoni receptor in the periodontal ligament in mice. PMID- 6927995 TI - Prevention of dental caries by acousto-optically Q-switched Nd: YAG laser irradiation. PMID- 6927996 TI - The relationship between calculus index and protease activity in saliva. PMID- 6927997 TI - Effects of extra-oral exposure and multiple avulsions on revascularization of reimplanted teeth in dogs. PMID- 6927999 TI - Maternal and gestational influences on deciduous and permanent tooth size. PMID- 6927998 TI - Correlations between root length and face size. PMID- 6928000 TI - The influence of fluoride on the seeded growth of apatite from stable supersaturated solutions at pH 7.4. AB - Previous studies have shown that fluoride affected the formation of apatite in spontaneous precipitations from unstable calcium phosphate solutions partly through its effect on the stability of such nonapatitic precursors as octacalcium phosphate, Ca8H2(PO4)6.5 H2O. The present study shows that fluoride had a comparable effect on the seeded growth of apatite from stable solutions when the degree of solution supersaturation favored the transient development of octacalcium phosphate precursors on the seed surface. PMID- 6928003 TI - The effect of desalivation upon pulpal function and dental caries in rats. AB - The role of pulp and saliva in caries susceptibility and resistance was evaluated using a combination of endodontic treatment and desalivation. Evidence was presented that the pulp plays a major role in caries susceptibility. It is suggested that pulpal function is modified by hormonal factor(s) originating from salivary glands. In the rat, saliva appears to play a minor role in resistance to caries. PMID- 6928002 TI - Effect of sodium fluoride on the viability and growth of Streptococcus mutans. AB - A fluoride-sensitive (FS) strain of Streptococcus mutans and a laboratory-induced fluoride-resistant (FR) offspring were compared for the effects of sodium fluoride on viability and growth. There was a significant fluoride-related loss of viability in resting cell suspensions of the FS strain during a 47-hour exposure to fluoride levels above 75 ppm that was not encountered with the FR strain. The addition of 300 ppmF to actively growing six-hour broth cultures almost totally arrested the growth of the FS strain, while only slightly reducing that of the FR culture. The addition of 600 ppmF immediately terminated FS growth, and greatly reduced the rate and maximum growth of FR cultures. PMID- 6928001 TI - Fluoride resistance and adherence of selected strains of Streptococcus mutans to smooth surfaces after exposure to fluoride. AB - The fluoride resistance and smooth surface adherence characteristics of Streptococcus mutans were examined using tooth model and radioactive cell assays. Resistance to 600 ppmF by S. mutans isolated from the plaque of radiation-induced xerostomia patients receiving daily topical applications of a caries preventive 1% NaF gel was transient. Resistance induced in vitro in two strains of S. mutans by exposure to gradually increasing levels of NaF was apparently permanent. Smooth surface adherence by both fluoride-sensitive and -resistant strains of S. mutans 6715 in a tooth model system was slightly diminished by 1% NaF gel. Fluoride-resistant strains retained 89 to 93% of their adherence capability in 600 ppmF, as determined by the cell radiolabeling assay. PMID- 6928004 TI - Subcutaneously implanted alginate as a continuous-release source of fluoride. AB - The fluoride concentrations of seven brands of alginate ranged from 8600 to 30,500 ppm. In acute and chronic in vivo studies, fluoride was continuously released from subcutaneously implanted alginate cylinders for up to three weeks. This technique is a simple and economical method for elevating soft and hard tissue fluoride levels. PMID- 6928006 TI - Demographic characteristics and breakdown by father's occupation of dental students in 1978--79. PMID- 6928007 TI - In defense of "rq". PMID- 6928009 TI - Integration of the basic, behavioral, and biomaterials sciences with the clinical curriculum. AB - An approach to effective integration of the basic, behavioral, and biomaterials sciences with the clinical curriculum is described. Teaching is accomplished by both scientists and clinicians on multidisciplinary teams. The instructional format is based on terminal objectives that are stated in behavioral terms. Examples of the objectives and the manner in which they are fulfilled are presented. PMID- 6928005 TI - Clinical, radiographic, and histological evaluation of porous rooted cobalt chromium alloy dental implants. AB - Forty-five cobalt-chromium alloy porous rooted dental implants were placed in dogs. They were evaluated periodically over two years. The implants were successful one-third of the time. Failures occurred early (two months) or late (after six). Attempts to explain the failures, early and late, are made. PMID- 6928008 TI - NIDR funding related to the presence of oral biology departments and source of basic science instruction. AB - The amount of research funds awarded to American dental schools by the National Institute of Dental Research (NIDR) in 1976 and 1977 was analyzed according to the schools' oral biology and basic science deparmental status. Four categories of schools were identified based on the presence or absence of oral biology programs (the ORB and NOB schools, respectively) and on medical school (-M) or dental school (-D) source of basic science instruction. This breakdown yielded 20 ORB-M schools, 7 ORB-D schools, 12 NOB-M schools, and 15 NOB-D schools. The ORB schools generated more than twice as much mean National Institute of Dental Research (NIDR) research funding per school as did the NOB schools. The rank order of funding in the four subgroups was ORB-M, NOB-D, ORB-D, and NOB-M. The rank order of NIDR research funding among these four subgroups was quite similar to the previously reported rank order of student National Board performance in the same subgroups. PMID- 6928010 TI - Visiting faculty as clinical evaluators for mock board examinations. AB - Applicants may fail state board examinations because of lack of practice under similar test conditions. Mock state board examinations employing visiting faculty as evaluators help students experience the stress of a real state board exam. Students become accustomed to strangers evaluating their work and receive unbiased evaluations. Other advantages and problems are discussed. PMID- 6928013 TI - Unusual spread of juxtacortical osteosarcoma. PMID- 6928012 TI - American Association of Dental Schools curricular guidelines. PMID- 6928011 TI - Retention of part-time faculty. AB - Part-time faculty members are a large and important part of teaching programs at dental schools across the nation. Retaining part-time faculty members is important in order to provide consistency of instruction and because training new faculty requires time and effort that otherwise would go into building a stronger teaching program. This paper discusses methods used at the University of Washington School of Dentistry department of restorative dentistry to keep the part-time faculty actively engaged in dental education year after year. These methods include involving the faculty members in the entire teaching program, providing them with inservice training, and doing some personal things for them. The methods have proved successful as shown by the retention rate in the last three years. PMID- 6928014 TI - Postoperative results of posterior maxillary osteotomy after long-term immobilization. AB - We have treated 22 patients for correction of open bite, using a one-stage posterior maxillary osteotomy, by two different techniques. Relapse was the most significant postoperative complication after this procedure. To avoid the high incidence and, particularly, the severity of this complication, we used long-term (11 to 12 weeks) maxillomandibular fixation to provide for neuromuscular adaptation to the newly derived rest position in the mandible. PMID- 6928018 TI - Primary mandibular neuroblastoma. PMID- 6928020 TI - Odontoameloblastoma. PMID- 6928015 TI - Skeletal and dental changes after surgical correction of mandibular prognathism. AB - Fifty cases of surgically corrected mandibular prognathism have been followed up and analyzed cephalometrically. This anatomy of relapse of the proximal and distal segments is described, as well as changes in the axial inclinations of the incisors. The physiopathology that may explain these spatial changes is advanced. PMID- 6928017 TI - The sequelae of surgical exposure of unerupted teeth. AB - The late effects of surgical exposure of unerupted teeth were analyzed. Of 121 teeth, 62 had only the crowns exposed; additional traction was applied to 31 teeth and 28 were repositioned. Postoperative observation time ranged from eight months to 13 years. One hundred and eleven teeth assumed their position in the arch and were deemed successfully treated; ten teeth failed to erupt. Of the successfully treated teeth, 23% showed biological aberrations such as obliteration of the pulp, dwarfed roots, and denervation. These pathophysiologic changes, alone or in combination, were commensurate with the amount of trauma inflicted on the teeth. Teeth that wer repositioned showed the most change, whereas teeth that only had crowns exposed showed the least change. PMID- 6928019 TI - Rhinomaxillary phycomycosis: report of case. AB - A case of rhinomaxillary phycomycosis has been reported. Although the occurrence of the phycomycetes-type of infection is relatively rare, the oral and maxillofacial surgeon should be alert for debilitated patients, especially uncontrolled diabetics, who may show the incipient signs and symptoms of this opportunistic fungal disease. PMID- 6928016 TI - Infection following intraoral surgical correction of dentofacial deformities: a review of 140 consecutive cases. AB - Prophylactic antibiotics are often administered during orthognathic surgery to prevent infection. A total of 140 consecutive patients who underwent "clean" intraoral maxillary and mandibular orthognathic surgery and received antibiotics in the preoperative period are reviewed with respect to postoperative infection. In four patients, infections developed, two of which were related to alloplastic implants. The microorganisms cultured from the infections were species not normally found in oral infections. One patient had an antibiotic-induced anaphylactic reaction. The theory and applicability of antibiotic prophylaxis for intraoral orthognathic surgery are discussed. PMID- 6928021 TI - Intraoral osseous choristoma: report of case. AB - A case of oral osseous choristoma of the buccal vestibule is presented. Of 27 reported cases, including this one, 24 occurred in the dorsum of the tongue, one in the ventral aspect of the tongue, and two in the buccal mucosa. There have been no recurrences reported after local excision. PMID- 6928023 TI - ADA House of Delegates approves use of phrase 'specialist in'. PMID- 6928022 TI - Computerized tomography in oral and maxillofacial surgery. AB - Computerized tomography has revolutionized the art of diagnosis by noninvasive techniques. Until recently, its use in oral and maxillofacial surgery has been limited. Basic principles include the production of a two-dimensional image representing an anatomically accurate slice of tissue. Advantages of computerized tomography are lack of image superimposition, preservation of detail of soft tissue, enhancement of vascular tumors, selective enlargement of areas of interest, tomographic capability, and the future possibility of the production of three-dimensional images. However, the presence of any metallic restoration produces artifacts, which limits the use of computerized tomography to areas excluding the dentition where restorations are present. Clinical application at our institution has been to use computerized tomography in the differential diagnosis of infections, midfacial trauma, vascular lesions, and lesions involving the mandibular ramus and maxilla. PMID- 6928024 TI - ADA accepts JCAH corporate membership invitation. PMID- 6928025 TI - Who's cheating whom? PMID- 6928026 TI - The anatomy of the internal maxillary artery in the pterygopalatine fossa: its relationship to maxillary surgery. PMID- 6928027 TI - Periodontal conditions in patients after molar uprighting. AB - Fifteen patients who had mandibular molars uprighted unilaterally and seven patients who had mandibular molars uprighted bilaterally were examined an average of 3 1/2 years after treatment had been completed. The investigation focused on differences in clinical observations between the treated teeth and the controls on the contralateral side at the time of the recall examination. Pretreatment radiographs provided longitudinal observations. After elimination of significant but unrelated factors, including surgical pocket elimination and the presence or absence of subgingival margins, the following appeared. Changes in alveolar bone height mesial to the uprighted molars were not different from changes mesial to control teeth. Gingival inflammation scores around uprighted molars were not different from those around control teeth. Pockets mesial to uprighted molars were shallower than those mesial to control teeth. Observations on pocket depth distal to the teeth considered were inconclusive. PMID- 6928028 TI - Effects of cast gold surface finishing on plaque retention. AB - The relationship between the surface finish on cast gold restorations and the amount of plaque deposited on that surface was examined. Six different finishes were tested. The rough finish was found to accumulate significantly less plaque than the other finishes. Every finish exhibited some plaque accumulation, even after the first 24 hours. Each finish accumulated progressively more plaque at each successive time interval. PMID- 6928029 TI - In vivo measurements of thermal diffusion through restorations of various materials. AB - Temperature diffusion was monitored through in vivo restorations with and without bases 0.5 and 1 mm thick. Temperature diffusion was highest through amalgam restorations and slowest through unfilled resin restorations. The rate of diffusion through composite resins and silicate cement fell between the extremes. Bases of both zinc phosphate cement and zinc oxide-eugenol cement reduced the rate of temperature change on the floor of the cavity beneath amalgam restorations. The temperature change was generally less under the 1 mm base than the 0.5 mm base. Bases used beneath the nonmetallic restorations did not reduce the magnitude of temperature change on the cavity floor. PMID- 6928031 TI - Recording centric-protrusive jaw relationship. PMID- 6928032 TI - Color stability of temporary restorative materials. PMID- 6928030 TI - The measurement of distortion: concluding remarks. AB - The means by which fine measurements can be made and distortions computed have been discussed in this series. However, the fact remains that research of this nature is time consuming and demanding. At every step, and in all machined components, care must be taken to eliminate local inaccuracies. Precalibration, postcalibration, and an ongoing program of maintenance are essential if quality results are to be anticipated. An attempt has been made to introduce automatic reading devices with the ability to compute distortions by having the raw data sent directly to a computer. This latter step can be highly dangerous unless at least one "test case" can be programmed into the system as a check on the data access and computational procedures. These test cases should simulate as closely as possible the actual computational requirements of the system, in order that all program "bugs" be corrected before the research is run. In this area, the GIGO rule, "Garbage in-Garbage out," holds true. Unfortunately, if the computational errors are small and of the order of magnitude of the measured distortions the researcher can accept the results without realizing there is a computational problem. PMID- 6928033 TI - How they did it: the synthesis of interferon. PMID- 6928036 TI - Blood flow in normal tissues and tumors during hyperthermia. AB - The effect of hyperthermia on the blood flow was studied in skin, muscle, and Walker 256 carcinoma implanted in the legs of SD rats. The radioactive microsphere method was used to measure the blood flow. Hyperthermia for 1 hour with water at 43 degrees C increased the blood flow in skin and muscle by about threefold to fourfold. On the contrary, hyperthermia had no appreciable effect on the blood flow in tumors. Consequently, during hyperthermia blood flow in the skin and muscle surrounding the tumors was greater than that in tumors larger than about 2 g. Despite the apparent increase in heat dissipation by the increased blood flow, the temperature of the skin was 42.6-42.8 degrees C, and the temperature at the core of tumors larger than 2 cm in diameter was 42.3-42.7 degrees C during the hyperthermia. The lower temperature in the muscle could be attributed to an increase in heat dissipation as a result of the increased blood flow. This differential rise in temperature by heating may account in part for the differential effect of hyperthermia on tumors and normal tissues in vivo. PMID- 6928035 TI - Host-derived antibody-dependent cytotoxic cells within murine tumors. AB - Mouse ascites tumor preparations had strong antibody-dependent cell-mediated cytotoxic (ADCC) activity, whereas cultured tumor cells did not. L5178 lymphoma cells reversibly expressed surface Fc receptors in vivo but not in vitro. Cultured lymphoma cells grown in vivo in diffusion chambers expressed Fc receptors but not ADCC activity. These results suggest that an Fc receptor is not sufficient to endow a cell with ADCC activity. The transplanted ascites tumors L5178 and MOT, an ovarian teratoma, contained about 2-5% host-derived cells, which represents a significant increase in the total number of host-derived peritoneal cells compared to the number of cells found in nontumor-bearing mice. These infiltrating host cells were separated from the ascites tumor cells by velocity sedimentation and by lysis with antibody and complement. In both instances, all the ADCC activity was associated with the host cells, whereas cells, such as killer cells and macrophage;, infiltrate ascites tumors and completely account for the potent ADCC activity associated with ascites tumor preparations. PMID- 6928037 TI - Immune response to inactivated syngeneic mammary adenocarcinoma cells. I. Role and regulation of antibody synthesis in DBA/2 mice. AB - The immunogenicities of irradiated T1699 murine mammary adenocarcinoma cells (XR T1699) and mitomycin C-treated T1699 cells (T1699m) were compared with respect to eliciting humoral immunity, cell-mediated immunity, and protection against subsequent sc challenge with untreated T1699 tumor cells (T1699u) in the syngeneic host (DBA/2 mice). Treatment with 10(3)-10(7) T1699m failed to induce any immunity against subsequent challenge with viable T1699u, whereas 10(6)-10(7) XR-T1699 sensitized the host to later challenge with T1699u. Although both T1699m and XR-T1699-sensitized mice displayed a delayed hypersensitivity response to soluble T1699 antigen as determined by footpad swelling, only XR-T1699-immunized mice developed detectable levels of anti-T1699 antibody, as measured by indirect immunofluorescence. The antibody-dependent cellular cytotoxicity (ADCC) titer of sera from XR-T1699-immunized mice peaked at day 11 and declined by day 20, whereas sera from T1699m- sensitized mice showed no detectable ADCC activity. Sera from mice with progressing T1699u tumors showed high levels of ADCC activity at all times tested. The immunity induced by XR-T1699 injection was shown to be specific for T1699 tumor cells and not limited to the anatomic area of immunization. The results are discussed in terms of the role of antibody as the primary protective mechanism in sensitization in the T1699 tumor model. PMID- 6928034 TI - Protection against anthramycin-induced toxicity in mice by coenzyme Q10. AB - Pretreatment of Swiss Webster mice with coenzyme Q10 (CoQ) markedly reduced the lethality of the antitumor antibiotic anthramycin as well as its ability to decrease ventricular weights. In tumor-bearing mice CoQ pretreatment did not produce any consistent alteration of radioactivity levels in blood, heart, tumor, lungs, kidneys, liver, muscles, brain, or spleen after [15-3H]anthramycin administration. Gross alterations in anthramycin distribution is probably not the mechanism by which CoQ alters the cardiotoxicity and lethality of anthramycin. PMID- 6928038 TI - Immune response to inactivated syngeneic mammary adenocarcinoma cells. II. Parameters of immunogenicity in DBA/2 mice. PMID- 6928039 TI - Kinetics of cell replication of the uterine cervix. III. Delayed migration in atypical epithelia of mice. AB - The migration of tritiated thymidine ([3H]dThd)-labeled cells toward the epithelial surface was recorded at various intervals (from 1 to 240 hr) in the normal and atypical cervical epithelial of 127 C57BL mice. Cervical atypias were induced by local application of 3,4-benzo[a]pyrene for 5 months9 This treatment was discontinued 7 days before the animals were killed. Cells were labeled by a single ip injection of 6 muCi [3H]dThd/g body weight. The disappearance of heavily labeled cells in normal animals 96 hours after the pulse and in solvent treated controls after 144 hours suggested that the original labeled cells had been exfoliated. However, cervical atypias showed heavily labeled cells as much as 240 hours after the [3H]dThd incorporation. Universal epithelial labeling (suggesting repopulation by daughter cells) usually occurred 24--48 hours after pulse labeling in normal and control animals but occurred after 96--240 hours in animals with atypical epithelium. On the basis of these results, the pace of both cellular intraepithelium transmigration and of epithelial repopulation by atypical daughter cells is substantially retarded during the early stages of cervical carcinogenesis. PMID- 6928040 TI - Metabolism and mutagenicity of N-nitroso-2-methoxy-2,6-dimethylmorpholine in hamsters. AB - N-Nitroso-2-methoxy-2,6-dimethylmorpholine (MeNDMM) was derived from the cyclic form of N-nitroso-(2-hydroxypropyl)(2-oxopropyl)amine (HPOP), a proposed proximate pancreatic carcinogen for the hamster. MeNDMM was metabolized in vivo by noninbred Syrian golden hamsters to HPOP, which was excreted in urine. In vitro metabolism produced HPOP by cytochrome P450-mediated oxidative demethylation. MeNDMM and HPOP were similarly mutagenic in the Ames Salmonella typhimurium assay, in which hamster liver preparations were used for metabolic activation. MeNDMM, due to its metabolism to HPOP, is probably also a pancreatic carcinogen in the hamster. PMID- 6928041 TI - Induction of cancer of the glandular stomach in rats by an extract of nitrite treated fish. AB - Treatment of a homogenate of the mackerel fish Sanma hirakl with nitrite at pH 3 led to the development of direct-acting mutagenic activity for Salmonella typhlmurium TA-1535. Repeated gastric intubation three times/week for 6 months of an extract containing this mutagenic activity into noninbred Wistar rats led to the induction of tumors in 8 of 12 rats 12-18 months later. Adenomas and adenocarcinomas were found in the glandular stomach, squamous cell carcinoma was observed in the forestomach, and adenocarcinoma was found in the small intestine and pancreas. Furthermore, precancerous lesions (including intestinal metaplasia and glandular hyperplasia of the glandular stomach as well as squamous cell hyperplasia) were noted in virtually all of the animals at risk. No tumors were seen in 8 control rats given the untreated fish extract alone; 1 rat had glandular hyperplasia and intestinal metaplasia. Thus a mutagenic extract of nitrite-treated fish was demonstrated to induce, in the rat glandular stomach, cancers identical to gastric cancer observed in man. Preventive m:asures, including reduction of the intake of pickled foods and the year-round daily availability of foods containing vitamin C, are discussed. PMID- 6928042 TI - Identification, characterization, and control of potential human carcinogens: a framework for Federal decision-making. AB - A two-stage process is proposed for a uniform framework for Federal agency decisions regarding the identification, characterization, and control of potential human carcinogens. Stage I would include the identification, through epidemiologic and/or laboratory studies, of chemicals that represent a potential carcinogenic risk and the characterization of that risk. Stage II would encompass the actual regulatory decision-making process regarding control of potential carcinogens. Stage I relies predominantly on scientific activity and judgment. Centralized management could enhance the efficiency and effectiveness of this process. The new National Toxicology Program may be able to perform this function. Stage II judgments are social and political. Centralization of stage II decision-making is not possible under current law. PMID- 6928043 TI - A case-control study of large bowel cancer in Japan. AB - This investigation of diet and other environmental factors reports on 588 patients with colorectal cancer and 1,176 hospitalized controls in three prefectures of Japan. Weak (not statistically significant) positive effects were found for social class and urbanization. The significant association of colorectal cancer with consumption of beef, string beans, or starches previously described for Hawaiian Japanese were not reproduced here. An association with hakusal (cabbage) agreed with other reports on a negative association with cruciferous vegetables. An analysis of the subset of cases in the low rectum yielded results similar to those for the total series. The failure to uncover important food effects in Japan is attributed to the difficulty of detecting case control differences in areas with homogeneous diet practices. Further epidemiologic research aided by leads from ongoing work with animals may provide ideas for more sharply defined questions, should stress new approaches for more accurate diet histories, and should continue to emphasize tumor localization. PMID- 6928044 TI - Relationship of hair dye use, benign breast disease, and breast cancer. AB - An epidemiologic case-control study of 118 breast cancer patients and 233 controls was conducted to test the hypothesis that hair dyes are related to breast cancer. Matched controls were selected by "random digit dialing," and all epidemiologic data were collected by telephone interviews. No overall association was detected. On a prospective basis, the interaction between hair dye exposure and six variables known to be risk factors for breast cancer then were examined: previous benign breast disease (BBD), "ever" versus "never" pregnant, age at first pregnancy, menopause induced by operation, age at menarche, and education. A statistically significant increased risk of breast cancer was found for women with a history of BBD and exposure to hair dyes as compared to women with BBD but no hair dye exposure: The relative risk (RR) was 4.5, and the 95% confidence intervals (C) were 1.20 and 15.78. A total of 24 women (19 patients and 5 controls) reported a history of BBD and hair dye use. Further analysis revealed a significant association between hair dye use and breast cancer among women 40-49 years of age (RR = 3.33; 95% CI: 1.1 and 10.85) and a highly significant (P = 0.0008) dose-response relationship among women who used hair dyes for changing their natural color as opposed to covering gray hair. The numbers of patients and controls included in this study were small and several hypotheses were tested. Additional epidemiologic studies are needed before firm conclusions can be reached concerning the nature of these associations. PMID- 6928046 TI - Plasminogen-activating activity: association with steroid binding by cytosols of human breast cancers. AB - Plasminogen-activating activity (PAA) was determined on cytosols prepared from human breast cancers. Coincident assays of steroid-binding proteins were obtained for 119 patients. Significant positive correlations were found between PAA and binding of: 1) estrogen (P less than 0.01), 2) progestin (P less than 0.001), and 3) triamcinolone (P = 0.01). Stepwise regression analysis indicated that variations in the levels of progestin binding accounted for 17% (P less than 0.01) and variations in the levels of triamcinolone binding for 3% (P = 0.05) of the variation observed in PAA. Use of the median value of each assay to discriminate positive from negative values accentuated the positive correlation between PAA and binding of 1) estrogen (P = 3.9 X 10(-5), 2) progestin (P = 1.9 X 10(-4), and 3) triamcinolone (P = 6.1 X 10(-5). Preliminary results suggested that values of PAA equal to or greater than the median correlated positively with response to treatment by hormone manipulation (P = 0.0549). Possible significance of these observations was discussed. PMID- 6928047 TI - Nonmutational alteration in glucocorticoid sensitivity of lymphosarcoma P1798. AB - The sensitivity of lymphosarcoma P1798 to glucocorticoids varied as a function of growth conditions. Cells grown in the ascitic fluid were very sensitive to cortisol inhibition of tritiated thymidine ([3H]dThd) incorporation. When ascites cells were inoculated sc into BALB/c mice receiving daily injections of 2 mg cortisol, tumors did not form. However, as tumors grew subcutaneously in control mice, glucocorticoid sensitivity decreased to the arrested by cortisol injection. Cortisol also did not inhibit incorporation of [3H]dThd in cells prepared from large subcutaneous tumors. Measurement of cytoplasmic receptors in cell-free extracts revealed that both ascites and subcutaneous tumor cells contained about 11-12 x 10(4) glucocorticoid binding sites per cell. Receptors in ascites cells had a higher affinity for glucocorticoids than did receptors in subcutaneous cells, which indicated that sensitive and resistant cells contain chemically different classes of receptors. Loss of sensitivity occurred as tumors attained a diameter greater than approximately 1.5 cm. The reproducibility of this transition did not appear to be consistent with a random mechanism for loss of glucocorticoid sensitivity in vivo. Thus the acquisition of resistance by lymphosarcoma P1798 in vivo was concluded to be nonmutational and probably resulted from differentiational alteration in gene expression. PMID- 6928048 TI - In vivo potentiation of 5-fluorouracil cytotoxicity against AKR leukemia by purines, pyrimidines, and their nucleosides and deoxynucleosides. AB - The effect of various natural pyrimidines and purines and their nucleosides and deoxynucleosides on 5-fluorouracil (FUra) cytotoxicity was examined against the transplantable AKR leukemia in female AKR mice. The spleen colony assay was used for a quantitative evaluation of the antitumor activity of the combination treatments. The base or nucleoside was administered 15 minutes before each mouse received an injection of 0.6 mg FUra. All of the compounds tested, with the exception of adenine, potentiated the cell-killing effect of FUra. On a molar basis (16-30 mumol/mouse), thymine, uracil, thymidine, and uridine enhanced FUra cytotoxicity more than a hundredfold. 2'-Deoxyuridine and the purine nucleosides and deoxynucleosides had similar potentiating activities between tenfold and fortyfold at 30 mumol per mouse. Finally, glucose, also administered 15 minutes before each mouse received an injection of 0.6 mg FUra, enhanced the antitumor activity of the drug by a factor of about five. PMID- 6928045 TI - Serum and urine protein differences in patients with malignant melanoma. AB - We used gel electrophoresis to fractionate serum and urine samples of patients with malignant melanoma and of healthy volunteers (controls) and observed that a) all proteins found in the sera of melanoma patients also occurred in the sera of 2 or more healthy volunteers, b) two minor protein bands were present in the sera of 73% of the melanoma patients but in the sera of only 38% of the controls, and c) one major band was present in the sera of 73% of the melanoma patients but in the sera of only 12% of the controls. We characterized these proteins by molecular size and charge. Two proteins, analogous in electrophoretic behavior to those found more frequently in melanoma patients' sera, were observed exclusively in the urine from melanoma patients. The demonstration of such differences in serum and urine proteins warrants the further study of this system as a serologic and/or immunologic test for diagnosis of malignant melanoma. PMID- 6928050 TI - Specific tumor immunity induced with mitomycin C-treated syngeneic tumor cells (MCT). Effects of carrageenan and trypan blue on MCT-induced immunity in mice. AB - Mitomycin C treatment of 3-methylcholanthrene-induced syngeneic tumor cells in male mice of the highly inbred strain CBA/WEHI was a convenient and effective method for producing viable but nondividing tumor cells. A single sc injection of 1 x 10(6) mitomycin C-treated syngeneic tumor cells (MCT) induced a specific antitumor immune response that could mediate rejection of small subcutaneous tumor grafts and substantially inhibit growth of larger grafts in normal mice. The response was evident between 3 and 7 days after immunization and persisted for at least 120 days. Adoptive transfer experiments with peritoneal exudate cells from MCT-immunized mice indicated that a cellular basis for resistance was likely in the absence of a detectable humoral component. Administration of MCT to mice with established tumor grafts did not, however, affect tumor growth. Experiments with carrageenan and trypan blue showed that neither induction nor expression of cytotoxic effector cells in MCT-immunized mice was inhibited by these substances, though carrageenan and trypan blue augmented tumor growth in normal mice. PMID- 6928049 TI - Incidence of urothelial tumors in rats deficient in essential fatty acids. AB - Wistar rats were fed a diet deficient in essential fatty acids (EFA). Control animals received the same diet to which was added 5% corn oil, a source of EFA. The experimental group showed clinical and chromatographic evidences of EFA deficiency. Groups of deficient and control animals were killed at various periods up to 100 weeks of age. Of 43 EFA-deficient rats, 8 (18.6%) had papillary transitional cell tumors of the urinary tract. None of the 36 controls had tumors (P less than 0.01). In 7 animals, tumors were found in the renal pelvis and upper portion of the ureter; in one, the tumor was in the bladder. The tumors were more frequent at the end of the first year of life and after the first year of life, with no significant sex differences. Tumors showed various degrees of differentiation and a trend toward bilateral involvement. Subepithelial and muscle invasion of tumor was noted in 5 rats. Most tumors were polycentric, and carcinomas in situ were seen. Atypical hyperplasias were found in 35% of the EFA deficient rats and in 3% of the controls. Typical hyperplasias were seen in 63% of the EFA-deficient rats and in 72% of the controls, Renal calcifications, congestion, inflammation, and hydronephrosis were also seen. No significant differences other than congestion were found in both groups. Our results suggest that the mechanisms regulating proliferation of urothelial cells are upset in EFA deficient rats; this favors the appearance of atypical hyperplasias and tumors. Therefore, EFA deficiency in the rat may be a useful model for the study of the causes and pathogenesis of human urothelial cancer. PMID- 6928051 TI - A two-disease model of female breast cancer: mortality in 1969 among white females in the United States. AB - A mathematical model of the age distribution of breast cancer mortality was developed on the basis of the two-disease theory of breast cancer incidence. The model included representations of the time from tumor initiation to death, the competing risk effects of other disease, and differential susceptibility to each of the disease components. This model successfully predicted the single year of age frequency of breast canceomponents of this model was consistent with several epidemiologic findings. Most significantly, the age distribution of breast cancer deaths from premenopausal disease was consistent with incidence patterns in non Western countries, where the incidence of the postmenopausal disease component was hypothesized to be lower because of nutritional differences. PMID- 6928052 TI - Curing Europe's biological death-wish. PMID- 6928053 TI - Biotechnology report urges 10 million pound programme "to match competitors". PMID- 6928054 TI - Prediction formulae for normal pulmonary function values in New Zealand European subjects. AB - The prediction formulae for normal pulmonary function values, VC, FEV1, FRC, RV, TLC and DCO, in New Zealand European subjects have been established for the first time. The 159 male and 169 female volunteers were aged 15--75 years and were non smokers and healthy. PMID- 6928055 TI - Ice treatment of injured ligaments: an experimental model. AB - Using the radiocarpal ligament of the domestic pig as an experimental model the effects of ice therapy were studied. The results indicate that application of ice causes: (1) Increased subcutaneous swelling to injured or uninjured soft tissue; (2) A diminution of histological evidence of inflammation in injured ligamentous tissue. PMID- 6928056 TI - Acute intravascular haemolysis due to quinine. PMID- 6928058 TI - The preoperative chest x-ray. PMID- 6928057 TI - Mesenteric xanthogranuloma: case report. AB - A case of mesenteric xanthogranuloma revealed as an incidental finding at laparotomy during cholecystectomy, is reported with a brief review of literature. PMID- 6928059 TI - Operating on outpatients. PMID- 6928060 TI - Medical manpower and child health care: a paediatric point of view. PMID- 6928061 TI - Notified viral hepatitis in Auckland. AB - One hundred and forty-nine patients notified in Auckland health district as suffering from hepatitis A or B during the period July 1978-June 1979 were investigated by health inspectors. The results were analysed by age, sex, ethnic group, potential source of infection and immunoglobulin prophylaxis of the contacts, and have increased the understanding of the epidemiology of these types of viral hepatitis in Auckland. PMID- 6928062 TI - Toxocara canis: the risks of infection. PMID- 6928063 TI - Oesophageal ulceration associated with ingestion of doxycycline. PMID- 6928064 TI - The first New Zealand isolation of Leptospira interrogans serovar australis. PMID- 6928065 TI - The incidence of femoral neck fractures in New Zealand. AB - This study reviews the incidence of femoral neck fractures in New Zealand Maoris and non-Maoris. A comparison made with corresponding overseas studies shows that the New Zealand non-7aori age-sex incidence is one of the highest yet observed. Maori women are shown to have an incidence of hip fracture significantly lower than non-Maori women. These results are discussed in the light of the current debate on the aetiology of femoral neck fractures. PMID- 6928066 TI - Acute lymphocytic leukemia masquerading as acute osteomyelitis. A report of two cases. AB - Two children each developed a focal destructive bone lesion accompanied by intermittent fever, swelling, tenderness and elevated ESR. Blood counts were normal; bone marrow aspiration showed acute leukemia. The bone lesions healed in both patients after anti-leukemic therapy. We suggest that the similar roentgenographic appearance of osteomyelitis, bone infarction and focal destructive lesions in leukemia probably reflects a common, basically ischemic process of bone. PMID- 6928067 TI - [Root canals in permanent teeth]. PMID- 6928068 TI - [Preventive dentistry in home nursed mentally retarded patients]. PMID- 6928069 TI - Therapy of genetic diseases: a three-level approach. AB - Therapy of genetic diseases may be attempted at three different levels in the evolution of the disease process. At the first level, after clinical manifestations have appeared, methods are symptomatic and include diet, drugs, surgery, and avoidance of hazardous substances. At the second level, midway between the origin of the disease and the appearance of clinical manifestations, therapy consists of administration of a normal gene product, such as insulin in diabetes and factor VIII in hemophilia. At the third level, the origin of the disease, methods involve correcting the gene defect and are currently under investigation. PMID- 6928070 TI - Eosinophil colony formation in acute nonlymphoblastic leukemia. PMID- 6928072 TI - Bone marrow aspiration and biopsy. PMID- 6928073 TI - Percutaneous antegrade pyelography and nephrostomy guided by ultrasound. PMID- 6928074 TI - Metastatic melanoma to the bladder. PMID- 6928075 TI - Medical Grand Rounds from the West Virginia University Hospital. Testicular carcinoma. PMID- 6928071 TI - Hemoglobin switching: a cellular model. AB - Regulation of hemoglobin synthesis depends in part on the population of cells available for erythroid differentiation. Mouse erythroleukemia cells were cloned, and the clones were induced with dimethyl sulfoxide to test the relative induction of beta minor and beta major synthesis. Cells of line 745 produced approximately 35 percent beta minor after induction, and 39 clones of line 745 produced from 23 to 61 percent beta minor. Further subcloning of the clone that produced 61 percent beta minor led to three subclones, all of which produced more than 90 percent beta minor. Thus one kind of hemoglobin regulation occurs at the cellular level. PMID- 6928077 TI - A case of recurrent Boerhaave's syndrome. PMID- 6928076 TI - High blood pressure affects many adults: combat big killer. PMID- 6928078 TI - Epididymal tumors: a case report. PMID- 6928080 TI - Spontaneous splenic rupture in acute lymphoblastic leukemia: successful nonoperative management. PMID- 6928079 TI - Acute myelofibrosis terminating as acute myeloblastic leukemia. AB - The case of an 8-year-old girl in whom acute myelofibrosis developed is described. The patient was managed conservatively. A year later evolution to acute myeloblastic leukemia occurred, accompanied by myeloid and erythroid dyspoiesis and an elevated fetal hemoglobin level. A remarkable reversal of the marrow fibrosis occurred when the patient was treated with combination chemotherapy. Intensive chemotherapy combined with extensive transfusion support, and possibly bone marrow transplantation, may offer similar patients hope for a prolonged survival and possible cure. The nature of acute myelofibrosis and its differential diagnosis are discussed. PMID- 6928081 TI - Treatment of deep-bite cases. PMID- 6928082 TI - Anatomy of a manuscript. PMID- 6928083 TI - White spots--saliva and dental caries. PMID- 6928084 TI - Bruxism in allergic children. AB - A study of bruxism (tooth grinding) was conducted at the University of Miami School of Medicine, at Jackson Memorial Hospital, Miami, Florida, and at the Sleep Disorders Center, Mount Sinai MEdical Center, Miami Beach, Florida. A threefold incidence of this pernicious oral habit in allergic children was disclosed as compared to nonallergic children. Dental literature stresses psychogenic factors, occlusal maladjustments, systemic conditions, and occupational pursuits which do not pertain to most children. Allergy is rarely considered. Nocturnal bruxism may be initiated reflexly by increased negative pressures in the tympanic cavities from intermittent allergic edema of the mucosa of the Eustachian tubes. Embryologic, anatomic, and neurological relationships between the muscles of the eardrum, Eustachian tubes, and jaws have a primordial, common ancestry. Chronic middle ear disturbances may promote reflex action to the jaws by stimulating the trigeminal nuclei in the brain. Sleep studies at Mount Sinai Medical Center on allergic, bruxing children have produced some interesting but incomplete results. We are attempting to develop sophisticated devices for monitoring abnormal tubal function which may be the crux of the bruxism problem. PMID- 6928085 TI - Dimensional changes in the dental arches of orthodontically treated cases. AB - Integrated data from lateral cephalometric radiographs and study models of fifty three patients were studied to assess the interactions between dimensional changes occurring during orthodontic treatment and the postretention stability of these changes. A new technique was developed to study distal movement of canines. Distal movement of canines did not ensure a stable increase in intercanine width. There was no significant relationship between mesiodistal position of the first molars and changes in intermolar width. Eruption of the first molar in the postretention period was associated with greater stability in overbite. There was no great degree of correlation between depth of the curve of Spee and inclination of the occlusal plane or between changes in arch length and changes in inclinations of the incisors. PMID- 6928086 TI - Misuse of hand-wrist radiographs. AB - What is the diagnostic value of a hand-wrist radiograph? In orthodontics, we use information about skeletal age to reduce the variability in timing of the facial growth spurt during adolescence. This brief review of the pertinent literature demonstrates a consistent sex difference in the relationship between skeletal age and facial growth. Although hand-wrist radiographs may provide some information of value to the orthodontist with male patients, the radiographic exposure is not justified for most females. PMID- 6928087 TI - Tooth mineralization as an indicator of the pubertal growth spurt. AB - The commencement of adolescent peak growth velocity in body height and facial growth is closely related in timing to certain ossification events which occur in the hand and wrist. An investigation into calcification patterns of the teeth revealed a high degree of correlation between the stage of mineralization of the lower canine and these events. The possibility of the use of this tooth as a maturational indicator of the pubertal growth spurt is discussed. PMID- 6928088 TI - Point A revisited. AB - Point A cannot be accurately identified in all cephalometric radiographs. In instances where this landmark is not clearly discernible, an alternative means of estimating the anterior extremity of the maxillary base is shown. A point plotted 3.0 mm. labial to a point between the upper third and lower two thirds of the long axis of the root of the maxillary central incisor was found to be a suitable point (estimated point A) through which to draw the NAE line and one which most closely approximates the true NA plane. PMID- 6928089 TI - American Board of Orthodontics. Diplomate/diplomat. PMID- 6928090 TI - Nonextraction treatment started in the mixed dentition. An American Board of Orthodontics case report. PMID- 6928091 TI - Similarities in EEG sleep findings for Kleine-Levin syndrome and unipolar depression. PMID- 6928092 TI - The construction of linear resistances for the testing of ventilators. PMID- 6928093 TI - Hyperthermia and ketoacidosis during anesthesia in a child with glycogen-storage disease. PMID- 6928094 TI - Defect in a T-fitting connection. PMID- 6928095 TI - Ventilator hazard revealed. PMID- 6928096 TI - Chronic myeloid leukemia and lithium. PMID- 6928097 TI - The surgical resection and chemotherapy of metastatic osteogenic sarcoma of the right ventricle. AB - The case report of a patient with metastatic osteogenic sarcoma of the right ventricle who had had an interscapulothoracic amputation in October, 1970, and a left lower lobectomy in June, 1973, for pulmonary metastasis is presented. The patient was hospitalized in October, 1974, with signs and symptoms of right ventricular outflow obstruction and arrhythmia, and cardiac workup established the presence of a right ventricular tumor. The lesion was successfully resected using cardiopulmonary bypass, and the diagnosis of metastatic osteogenic sarcoma was confirmed. The patient did well after the operation and returned to normal activity. She was placed on adjuvant Adriamycin (doxorubicin) chemotherapy, but 6 months later died of Adriamycin toxicity. PMID- 6928098 TI - Chronic myelogenous leukemia. Association with 45 XO Philadelphia chromosome karyotype and prolonged survival. AB - A 42-year-old man with chronic myelogenous leukemia for ten years was found to have a 45 XO Philadelphia chromosome karyotype in myeloid cells with normal 46 XY pattern in peripheral blood lymphocytes. This chromosome pattern has been postulated to be associated with delay in onset of blastic transformation. The prolonged survival of this patient, with only minimal initial chemotherapy and lack of symptoms for ten years, lends support to the concept that the missing Y chromosome may be associated with a favorable prognosis in Philadelphia chromosome-positive men with chronic myelogenous leukemia. PMID- 6928100 TI - The association looks at itself. PMID- 6928099 TI - Sarcomas of the larynx. AB - From 1949 to 1974, 17 patients with sarcomas of the larynx were treated at the Mayo Clinic. Histologically, the sarcomas were classified as fibrosarcoma (six tumors), chondrosarcoma (seven tumors), rhabdomyosarcoma (three tumors), and osteosarcoma (one tumor). Patients with chondrosarcomas tended to differ from patients with other sarcomas in respect to origin of the sarcoma and length of survival free of disease. PMID- 6928101 TI - The relationships between irregular teeth, plaque, calculus and gingival disease. A study of 300 subjects. PMID- 6928103 TI - The National Institutes of Health in the U.S.A. PMID- 6928102 TI - Procaine penicillin psychosis. PMID- 6928104 TI - Combination chemotherapy of adult acute lymphoblastic leukemia with randomized central nervous system prophylaxis. AB - Although major progress has been made in the treatment of childhood leukemia, the optimal chemotherapy of acute lymphoblastic leukemia (ALL) in adults has been unclear. In addition, the value of central nervous system prophylaxis (CNS-P) in adults has been assumed, but not established in a systematic fashion. The Southeastern Cancer Study Group has completed a prospective study in which the use of vincristine plus low-dose methotrexate and high-dose prednisone in adult acute lymphoblastic leukemia has produced an 80% (79/99) complete remission rate in patients age 15 yr and over. Younger patients had a significantly higher remission rate but no increase in remission duration. This induction regimen was associated with minimal toxicity. Random assignment to CNS-P or to no prophylaxis, after a multidrug consolidation regimen, has demonstrated a significant prolongation of CNS relapse-free interval (p=0.008) in favor of CNS P. CNS-P did not improve hematologic remission duration or survival. All complete remitters were maintained on mercaptopurine, methotrexate, and cyclophosphamide with pulses of prednisone and vincristine; the median time from remission to either hematologic or CNS relapse was 19.3 mo after CNS-P, and survival for these patients was 26.1 mo. We conclude that our current induction regimen is highly effective in adult ALL and that CNS-P prophylaxis is indicated in such patients. PMID- 6928105 TI - "Microgranular" acute promyelocytic leukemia: a distinct clinical, ultrastructural, and cytogenetic entity. AB - Three patients with acute leukemia, disseminated intravascular coagulation, and a specific acquired chromosome abnormality [t (15;17)] were found by transmission electron microscopy to have the typical distribution of granules seen in promyelocytes. However, the average granule sizes were 120, 170, and 180 nm, respectively, for the three patients, significantly less than the 250-nm resolution of light microscopy. We regard the leukemia in these three patients as comprising a distinct clinical, ultrastructural, and cytogenetic entity that we have chosen to call "microgranular" acute promyelocytic leukemia. PMID- 6928107 TI - Masking of neutrophil surface lectin-binding sites in chronic myelogenous leukemia (CML). PMID- 6928106 TI - Discrimination of human leukemia subtypes by flow cytometric analysis of cellular DNA and RNA. AB - A newly developed flow cytometry technique for simultaneous measurements of three features of individual cells--DNA, RNA, and nuclear diameter--using acridine orange as a fluorescent metachromatic dye, has been applied to cell-cycle analysis. DNA stemline determination, and to classification of 102 cases of human leukemias in adults. Acute lymphoblastic leukemia (L1-2) was characterized by moderately increased RNA of G0/1 cells as compared to normal lymphocytes; acute nonlymphoblastic leukemia (M 1-5) by very high RNA of G0/G1 cells. Both had either diploid or aneuploid DNA stemlines. Chronic lymphocytic leukemia showed diploid DNA, very low proliferation, and low RNA, similar to that found by use to be typical for normal B cells. In chronic myelogenous leukemia, two cell populations were distinguished, one with high RNA, the other with very low RNA and elongated nuclear diameter due to stripped, unfolded nuclei of polymorphonuclear leukocytes. The number of leukemic blast cells, identified by aneuploid DNA values, correlates well with conventional microscopy counts and could be followed during the course of treatment. Thus, acridine orange flow cytometry can be used to discriminate subtypes of human leukemias, to determine cell cycle stages, and to detect and monitor aneuploid leukemia stemlines. PMID- 6928110 TI - The diagnosis and grading of chondrosarcoma of bone: a combined cytologic and histologic approach. AB - The diagnosis and grading of chondrosarcoma of bone is best established by a complementary study of its cytology, as observed in smeared preparations, and of its tissue structure and relationship to the host bone, as observed in histologic sections. Smeared preparations demonstrate the cytologic features of chondrosarcoma with greater clarity and detail than is possible with histologic sections. Histology is particularly helpful in the diagnosis of low-grade chondrosarcoma, through the demonstration of its invasive activity in relation to the host bone. The importance of grading chondrosarcoma is emphasized because of its relevance to the biological behaviour and prognosis of this tumor. PMID- 6928108 TI - A subtype of the prototypic karyotype in acute myeloid leukemia t (8; 21) (q22; q22), del 9 (q13; q23). AB - Two patients with acute myeloid leukemia are described in whom G- and C-banding analysis of bone marrow cells revealed, besides the translocation t(8;21), an additional structural anomaly characterized by the deletion of bands q13 to q23 of one chromosome no. 9. Findings in the literature support the proposal that this constellation represents a hitherto unreported subtype of the prototypic karyotype in AML. PMID- 6928109 TI - Binding of lectins to leukemic cell lines. AB - The binding of 12 different fluorescein-conjugated lectins to 10 ALL (acute lymphoblastic leukemia) cell lines and two cell lines derived from patients in blast crisis of myeloid leukemia was examined. The specificity of the membrane fluorescence was demonstrated by inhibition with various saccharides. Three of the lectins bound to all cell lines, four bound to only some of the lines, and five were not bound. There was no correlation between the binding pattern and the immunological phenotype of the cultured lymphoblasts. The lectin from Lens culinaris, however, in the experimental condition used (incubation at 4 degrees C, fluorescein conjugation at pH 8.5), bound only to the cell membranes of 'Ia like antigen, positive cell lines. Although three lectins (Lens culinaris, Pisum sativum, concanavalin A) had an identical monosaccharide specificity, they bound to different cell lines. Membrane fluorescence with the lectins from Helix pomatia, Arachis hypogea, and Ricinus communis (MW 60,000) was achieved after treatment with neuraminidase. It was shown that binding of the lectins from Helix pomatia and Ricinus communis 60 was effected by enzymatically exposed glycoproteins, whereas the lectin Arachis hypogea was bound via neuraminidase which stuck to the cell membrane. PMID- 6928111 TI - Cleft palate velopharyngeal musculature in a five-month-old infant: a three dimensional histological reconstruction. AB - The structure of the velar muscles in a five-month-old infant with a cleft of the secondary palate was studied using the Plexiglas reconstruction method based on serial histological sections. The right side was sectioned horizontally and the left side in the coronal plane. Sections were projected at a magnification of 18, and muscle fibers and bone and mucosal surfaces were drawn on Plexiglas sheets. Each reconstruction was divided into representative levels which were described in detail. The three-dimensional reconstructions vividly demonstrated the anterior insertion of the levator, palatopharyngeus, and uvular muscles, and the abnormal anterior position of the velar muscles generally. The levator muscle appeared to be in a position to obstruct the auditory tube during muscle contraction. The palatoglossus muscle evidently received a substantial contribution of muscle fibers from levator as well as from some fibers originating from the pterygoid hamulus. A bundle of muscle fibers from the tensor muscle did not pass around the pterygoid hamulus but coursed anteriorly to insert on the maxillary tuberosity. The results provided fresh support for the case of intravelar surgical reorientation of the abnormally inserted muscles. PMID- 6928112 TI - Craniofacial analysis of patients with complete clefts of the lip and palate. AB - The timing of habilitative treatment in the individual with cleft lip and palate has received a great deal of attention, but the most judicious age for performing primary palatoplasty is still a contested issue. Some reports in the literature speak of "early" and "traumatic" surgery as being analogous, while other investigators find early surgery entirely compatible with normal growth and development. Records were obtained on 19 patients with unilateral and 9 with bilateral clefts of the lip and palate operated upon at the same age by the same surgeon and utilizing the same surgical technique. Cephalometric tracings were recorded, measured, and analyzed by an Amdahl 470-V computer. Results indicate that, in both unilateral and bilateral clefts, there is a definite decrease in overall mid-facial growth, both horizontally and vertically, but that there is an apparent tendency for the components of the lower face, especially the mandibular body, to "compensate" for changes in midface development. Although skeletal structures of the cleft subjects are significantly altered when compared to non cleft control subjects, the general clinical appearance of the patients does not substantiate the criticisms of those opposed to "early" surgical intervention. PMID- 6928113 TI - Impaired weight gain in cleft palate infants. AB - The weight records for the first six months of life of 37 infants with cleft palates were reviewed in an effort to quantitate their early feeding difficulties. None of the families had had special feeding training until problems were well established. The median birth weight (plotted against standard curves) was at the 30th percentile. At the end of one and two months of age, the median weight ranking had fallen to the 20th percentile, and did not recover to birth levels (30th percentile) until the sixth month. This information is useful in counseling families of cleft children and in introducing special feeding instruction as soon as possible after birth. PMID- 6928114 TI - Delayed hard palate repair and speech deficiencies: a cautionary report. AB - In the management of patients with complete palatal clefts early repair of the soft palate (before 1 year of age) and delayed repair of the hard palate (after five or six years of age) has been advocated on the basis that good speech will develop following soft palate closure and that avoidance of trauma to the hard palate will obviate maxillary growth disturbance. In addition, it is said that many of the remaining hard palate fistulas will close spontaneously and that residual hard palate openings will be easy to close. Thirty-two cases treated in this way are reviewed, and a decade of experience with this technique is presented. A majority of cases failed to develop acceptable speech spontaneously. A very high percentage suffered both anterior and posterior air escape and a strikingly high proportion required pharyngeal flaps. Spontaneous complete closure of the hard palate was infrequent. The hard palate openings were not easy to close. The speech deficiencies associated with this technique are clear. The method's possible advantages in relationship to maxillofacial growth remain difficult to prove and were not specifically investigated in this study. PMID- 6928115 TI - Late correction of orbicularis discontinuity in bilateral cleft lip deformity. AB - The absence of muscle in the prolabial segment and the failure to identify and join the fibers of the orbicularis muscle from the lateral lip segments at the time of initial lip repair frequently result in a characteristic bulge above the vermilion laterally. This bulge is caused by the bunching of the orbicularis oris as the result of its discontinuity in the prolabial segment. Late repair of this deformity is possible. In a series of fifteen patients with previously repaired bilateral cleft lips, lateral mobilization and midline suturing of the separated segments of the orbicularis oris muscle have been employed to correct the orbicularis bulge. Significant improvement in oral animation and in facial aesthetics have been noted in these patients. PMID- 6928116 TI - A cephalometric study of velar stretch in adolescent subjects. AB - Cephalometric x-rays were used to evaluate velar stretch in 20 normal adolescents during the production of /s/. Radiopaque markers were used so that the behaviors of both the anterior and posterior portions and the total velum cound be evaluated. Velar stretch was found in each of the subjects with the average stretch (15.19%) greater than the amount reported for 10-year-old subjects but less than the average stretch for adults. The correlation between amount of velar stretch and need ratio was not significant. The different stages of involution of adenoid tissue, which is characteristic of this age group, resulted in varying configurations of the naso-pharynx were postulated as one possible explanation for this unexpected finding. Normative data and clinical implications are presented. PMID- 6928117 TI - A family with the popliteal pterygium syndrome. AB - A family with the Popliteal Pterygium Syndrome is presented. The father was born with a cleft of the palate and lower lip pits. Two of the three offspring showed extensive involvement of the palate, gums, and lips with minimal involvement of the lower limbs, genitalia, and nails. PMID- 6928118 TI - The penetrance and variable expression of the Van der Woude syndrome: implications for genetic counseling. AB - The presence of congenital fistulae in the lower lip in combination with cleft lip, cleft palate, or both is diagnostic of the Van der Woude syndrome. This autosomal dominant syndrome had been reported to have a penetrance of 80% with variable expression. An analysis of eleven families with 67 affected individuals showed variable expression of clefting and lower lip pits. However, penetrance was found to be close to 100%. An approach to counseling advocates advising a 50% chance of inheriting the gene for Van der Woude syndrome. PMID- 6928120 TI - Craniofacial and extracranial malformations in the Klippel-Feil syndrome. AB - The Klippel-Feil syndrome is of special interest to those concerned with cleft palate for the following reasons: (1) Cleft palate is a commonly associated finding: (2) malformations of the cervical vertebrae, in the absence of other stigmata of the syndrome, are a common finding in cleft palate; (3) anomalies of the upper cervical column and cranial base can impede velopharyngeal valving; (4) hearing loss is a common finding in the syndrome irrespective of the presence or absence of cleft palate; (5) cervical anomalies may complicate endotracheal intubation or head extension during pharyngeal surgery, and (5) the short neck may be the primary defect that impedes palatal fusion. This report reviews the literature on 339 patients and seven new cases in an effort to catalog the cranial and extracranial malformations associated with the syndrome and to consider the mode of genetic transmission. PMID- 6928119 TI - Clefts in quintuplets--a case report. AB - A report of clefting in three siblings of quintuplets, following treatment with Pergonal, is presented. It is suggested that the varying degrees of the abnormality may be related to cramped intra-uterine conditons or differing pressures at a critical developmental stage. To our knowledge, no previous reports of congential abnormalities associated with Pergonal therapy exist, and we feel that the causal relationship should be explored using a suitable animal model. PMID- 6928121 TI - Bullous pyoderma gangrenosum with chronic myelogenous leukemia: report of a case. AB - A case of bullous pyoderma gangrenosum is presented in which study of the patient led to the discovery of chronic myelogenous leukemia. PMID- 6928122 TI - Differentiation between glycogenosis types Ia and Ib by measurement of extra respiration during phagocytosis by polymorphonuclear leukocytes? PMID- 6928124 TI - Induction of erythroid differentiation in murine erythroleukemic cells by short chain aliphatic carbonyl compounds and their corresponding precursors. Evidence for common inducing signal. PMID- 6928125 TI - Development of the steroid-producing cells during the transformation of the right gonad into a testis in ovariectomized chicks. PMID- 6928123 TI - Commitment to differentiation in Friend cells and initiation of globin mRNA synthesis occurs during the G1 phase of the cell cycle. PMID- 6928126 TI - [Phage pf16 interrelationships with Pseudomonas putida bacteria. I. Unstable transductants and mutants of Pseudomonas putida PfG1 resistant to phage pf16]. AB - The frequencies of transduction of the chromosomal genes by pf16 in Pseudomonas putida PgG1 are dependent on the marker transduced and unpredictable. Histidine and isoleucine-valine positive transductants, which are resistant to pf16, have been selected in the crosses with low (about 10(-8) for phage units) frequencies of transduction. Some of these transductants carry new mutations. The transductants are unstable for phage resistance and histidine or isoleucine valine positive characters. There is no correlation between segregations of the auxotrophic and phage sensitive clones. Among 200 tested mutants of P. putida line PpG1, which were obtained by the direct selection for the resistance of pf16, 3 mutants are found to be auxotrophic for histidine and one mutant unstable for the phage resistance character. The culture medium of such histidine negative and phage resistant mutants as much as phage resistant transductants lyse the lawn of the sensitive to pf16 strains, but viable phages are produced only by those unstable for the phage resistance character. These phages are very similar to pf16 for such characters as host range, size and morphology of plaques, latent period, burst size, transducing ability and the degree of inactivation by pf16 antiserum. The pf16 resistance of mutants and transductants is caused by the disturbing of phage adsorption. Possible mechanisms for the lisogenization of P. putida by pf16 are discussed. PMID- 6928127 TI - Accreditation problems: programs move toward integration. PMID- 6928128 TI - Writing maketh an exact man. PMID- 6928130 TI - The effects of water conditioning on fluoride concentration. PMID- 6928132 TI - Developmental dental anomalies in chondroectodermal dysplasia (Ellis-van Creveld syndrome). PMID- 6928131 TI - Space observation following loss of the mandibular first primary molars in mixed dentition. PMID- 6928129 TI - Responses of enamel, dentin, and root surfaces to mouthrinse concentrations of sodium fluoride and stannous fluoride. PMID- 6928133 TI - The etiology of oligodontia: a family history. PMID- 6928134 TI - A cephalometric study of the developmental relationship between primary and permanent maxillary central incisor teeth. PMID- 6928135 TI - Microscopic observations of the dentin under caries lesions excavated with the GK 101 technique. PMID- 6928137 TI - The anachoretic effect in root resorption: report of case. PMID- 6928136 TI - Prosthetic problem and solution in the primary dentition: report of a case. PMID- 6928138 TI - Employing a sodium fluoride tablet supplement during pregnancy. PMID- 6928139 TI - No hygienists in general practice residency manual? PMID- 6928140 TI - Occlusal splints. PMID- 6928141 TI - The long needle. PMID- 6928142 TI - Injection study. PMID- 6928144 TI - Hepatitis B. PMID- 6928145 TI - National Health Service. PMID- 6928146 TI - Iron-on transfers part of "Smile America" campaign for 1980 National Children's Dental Health Week. PMID- 6928143 TI - Cephalexin. PMID- 6928147 TI - Dysesthesia after mandibular third molar surgery: a retrospective study and analysis of 1,377 surgical procedures. AB - To statistically associate specific factors of surgical extraction of third molars with mandibular nerve dysesthesia, records of patients were reviewed for preoperative panoramic radiographs, complete operative and anesthetic records, preoperative and postoperative notes, and histories. Data were then tabulated and the cases of altered sensation were compared with cases of unaltered sensation. PMID- 6928148 TI - Effect of Dycal on bacteria in deep carious lesions. AB - Indirect pulp capping procedures are often dependent on use of calcium hydroxide which is placed directly over residual carious dentin. As the bacterial count was found to decrease a month after the calcium hydroxide was placed, this study was done to assess how much of the change was caused by the use of Dycal and how much was caused by the mechanical access procedures. PMID- 6928149 TI - Effects of the Myo-monitor on cardiac pacemakers. AB - Interference of Myo-monitor stimulus on normal function of cardiac pacemakers depends on the sensitivity of the pacemaker and the amplitude setting of the stimulator. Because of electrical isolation of the fixed-rate pacemaker, it is resistant to interference and is unaffected by the Myo-monitor. PMID- 6928150 TI - Survey of dentists' attitudes regarding instructions for home care for patients who wear dentures. AB - Continuous wearing of dentures may contribute to inflammatory papillary hyperplasia and alveolar bone resorption. A group of dentists were surveyed to determine how they were trained to instruct patients who wear dentures and what they currently recommend concerning continuous wear of dentures. PMID- 6928151 TI - Relationship between allergy and bruxism in patients with myofascial pain dysfunction syndrome. AB - The relationship between allergy and bruxism was examined in three groups: patients with myofascial pain-dysfunction, patients with organic disorders of the temporomandibular joint, and patients without temporomandibular joint disorders. PMID- 6928152 TI - Solitary neurofibromatosis in the maxilla: report of oral findings. AB - Clinical and histological manifestations of von Recklinghausen disease are reviewed. The oral findings in a patient with a solitary maxillary plexiform neurofibroma are described. PMID- 6928153 TI - Natal and neonatal teeth. AB - Incidence, causes, complications, and treatment of natal and neonatal teeth are presented. It has been suggested that the terms mature and immature be added to the designation of this anomaly as those would imply the development and prognosis of the tooth and give clinical significance to the terms natal and neonatal. A case in a 2-week-old premature infant is described. As natal or neonatal teeth seldom develop properly and subsequent loss of space is not a long term sequela, extraction is the preferred treatment. PMID- 6928154 TI - Gasoline-induced mucositis. AB - Gasoline-induced mucositis may become more common because of fuel shortages or increased fuel cost. Dentists should, therefore, consider this oral irritant in the differential diagnosis of oral lesions. PMID- 6928156 TI - Status report on low-gold-content alloys for fixed prostheses. Council on Dental Materials, Instruments, and Equipment. AB - Because of their savings in cost and comparable mechanical and handling properties, low-gold-content dental casting alloys will remain an attractive alternative to high-gold-content alloys. Certain compositions perform well in the corrosive oral environment; others do not. Accurate information on such performance is currently unavailable. Accurate prediction of tarnish and ocrrosion behavior awaits development and acceptance of reliable and valid performance tests. There is adequate evidence that not only the Ag, Cu, and Pd ratios are important for resistance to corrosion but also the addition of minor amounts of other elements may be important for adequate clinical performance. PMID- 6928155 TI - Use of conventional endodontic therapy in a case of veterinary medicine. AB - An Air Force veterinarian consulted with an Air Force endodontist concerning the fractured canine in a German shepherd sentry dog. Exposure of the pulp was evident and root canal therapy was initiated; general anesthesia was used. Problems were encountered in preparation of the canal because of its length. Conventional endodontic therapy was completed at a second appointment after custom instruments and filling materials were designed and constructed to compensate for the length of the canal. Successful conventional endodontic therapy was performed on a valuable military dog. Surgical intervention was avoided by designing custom-made materials. Endodontic principles were successfully applied to serve as definitive treatment in veterinary medicine. PMID- 6928157 TI - Certified dental technician program. Council on Prosthetic Services and Dental Laboratory Relations. PMID- 6928158 TI - Addendum to American National Standards Institute/American Dental Association Specification No. 1 for alloy for dental amalgam. Council on Dental Materials, Instruments, and Equipment. PMID- 6928159 TI - Council reevaluates position on dental endosseous implants. Council on Dental Materials, Instruments, and Equipment. PMID- 6928161 TI - Harvard research focuses on early detection of periodontal disease. PMID- 6928160 TI - New techniques aid ADA research in cleft lip, palate prevention. PMID- 6928162 TI - Controlling the cost of care. PMID- 6928164 TI - Dr. Dunning responds. PMID- 6928165 TI - Esthetics: a comparison of dentists' and patients' concepts. AB - Drawings and photographs of shape, symmetry, and proportion of maxillary central incisors were evaluated by 112 dentists, 215 dental sutdents, 399 male patients, and 695 female patients. A significant difference was found between the evaluations of patients and dentists; the preferences of dental student; were between those of patients and dentists. Male and female patients had similar opinions. PMID- 6928163 TI - Rationale for Dr. Knutson's plan. PMID- 6928166 TI - Female dental students: current status, motivation, and future plans. PMID- 6928168 TI - Nutritional knowledge and attitudes of dental students. AB - The nutritional knowledge and attitudes of 230 dental students were studied. The students answered 68.6% of the nutritional knowledge questions currectly, but the test scores were low because they were adversely affected by the degree of certainty. First-year students scored significantly higher than fourth-year students. There was no significant difference between scores of men and women. Knowledge scores were highest for questions on nutrition and oral health and lowest for those on nutritional assessment. Dental students generally expressed favorable attitudes toward nutrition and nutritional care of patients. They agreed that dentists were vital members of the health team and had a responsibility to become involved in health screening and nutrition education of patients. Dietitians were seen as valuable resources to be consulted about nutrition education of the dental patient. More first-year students supported the idea that dentists should prescribe nutritoinal supplements for patients, whereas more fourth-year students were undecided about this matter. There were no differences in nutrition attitude scores attributable to gender of the student or year in dental school. In this study, nutritional knowledge scores did not correlate with nutrition attitude scores. PMID- 6928169 TI - Orthodontic procedures that improve the periodontal prognosis. AB - Osseous defects not amenable to conventional resective or regenerative osseous surgery alone may respond to a combination of orthodontic and periodontal techniques. Two orthodontic procedures-correction of mesially tipped teeth and forced eruption-have been described that may enhance the periodontal prognosis. Each procedure is accomplished with use of sectional orthodontic appliances and each requires a short time for treatment. Beneficial results include improvement of the crown-to-root ratio, reception of the forces of occlusion in the long axis of the tooth, and reduction or elimination of infrabony defects. PMID- 6928167 TI - Studies on cross-contamination in the dental clinic. AB - The purpose of this study was to determine the amount of cross-contamination of potential pathogens currently occurring in the dental hygiene clinic at the Ohio State University. Results of this investigation show that there is a significant amount of cross-contamination in the clinic. Potentially pathogenic organisms were transferred from the patients' mouths to the fingers of the dental hygiene students, and then to the switches on the dental chair unit and to the handles of the sink. Use of 5% iodophor in 70% isopropyl alcohol was effective in sterilizing certain fomes in the dental operatory. PMID- 6928170 TI - Labial pulpectomy access followed by esthetic composite resin restoration for nonvital maxillary deciduous incisors. AB - A 3-year-old girl had a darkened and symptomatic maxillary right deciduous central incisor. This report describes the rationale and technique for a labial pulpectomy access opening and subsequent composite resin restoration. This innovative approach for the pulpal treatment of these deciduous incosors not only improves the access for instruments and direct visualization for the operator but also greatly improves the appearance of the dark teeth without complete coverage. Two other clinical applications of this labial approach should also be mentioned. First, anterior stainless steel crowns can be made esthetically pleasing by placing labial resin facings in the crown. Second, access for pulpotomy procedures can be improved with use of a labioincisal approach after the incisal reduction step in the preparation of deciduous incisors for complete coverage. PMID- 6928171 TI - Clinical significance of taurodontism. AB - In an attempt to determine the clinical significance of taurodontism, two reports of cases of patients with the anomaly have been presented. It seems that the taurodont form does not interfere with routine operative procedures, but it is suggested that the morphology might hamper the location of orifices and could create difficulties in instrumentation and obturation in endodontic treatment. It is hoped that other cases involving the treatment of taurodont teeth will be reported to aid in determining the clinical significance of the anomaly for other areas of dentistry. PMID- 6928172 TI - Swallowing of central bearing plate. AB - While he was being fitted for complete dentures, the patient swallowed the central bearing plate that had become detached. The plate was lodged in the hypopharyngeal region of the pharynx and, with the patient under intravenous sedation, laryngoscope and biopsy forceps were used to retrieve it. Precautions that must be taken to prevent such occurrences include the proper attachment of the device components and testing for security, as well as upright positioning of the patient. The components should be explained to patients and they should be given instructions to eject immediately any part of the device that becomes dislodged. PMID- 6928173 TI - Pseudohypertension due to medial calcific sclerosis. AB - A hypertensive crisis requires rapid diagnosis and treatment to prevent serious sequelae. A patient with medial calcific sclerosis, however, may appear to have extremely elevated blood pressure values but, in effect, be normotensive. Consideration should be given to this condition when the patient's clinical appearance does not reflect the extremely elevated blood pressure values as measured. PMID- 6928174 TI - Intraoral Hymenoptera sting. AB - Four days before a routine dental examination, the patient had been stung on the left side of the soft palate by a yellow jacket. The lesion was well demarcated, with a prominent area of deep red erythema approximately 1.5 cm in diameter. inside of which was a coral pink ring approximately 0.5 cm in diameter. The patient was not experiencing discomfort at the time of examination. Reactions to Hymenoptera stings usually include pain, erythema, and swelling, but, in more severe instances, extensive swelling and systemic reactions in the form of anaphylaxis or delayed allergic responses may be seen. The patient should be referred immediately to a physician or medical treatment facility for observation and treatment if necessary. If the stinger is located either periorally or intraorally, it should be carefully removed by flicking so that additional venom from the sac is not injected into the patient. PMID- 6928175 TI - Behaviors of dentists in regard to dental and medical appointments. ADA Health Foundation Research Institute. AB - During the Health Screening Program at the ADA's annual session, 1,160 dentists completed questionnaires about their personal medical and dental visits within the past year. Findings from this study were compared with findings from other surveys of these behaviors in the general population. Results indicated that dentists visited dentists more often than did members of the general population. Dentists' visits to physicians were fewer than those reported by the general population. PMID- 6928176 TI - American National Standards Institute/American Dental Association Specification No. 44 for dental electrosurgical equipment. Council on Dental Materials, Instruments, and Equipment. PMID- 6928177 TI - The second session of the 96th Congress: not much time for business. PMID- 6928178 TI - The radiation hazard in perspective. PMID- 6928179 TI - Women, myths, and dentistry. PMID- 6928180 TI - Some understandings and misunderstandings about insurance. PMID- 6928181 TI - A convenient animal model for testing bone substitute materials. AB - There is consijerable interest in developing substitute materials for bone to perform the functions of autogenous bone grafts. However, a persistent problem is finding a suitable animal model in which to test the biodegradable implants. This paper reviews the requirements of an ideal animal model for this purpose and discusses the shortcomings of existing procedures. A technique is described that uses the cranial vault of the rabbit and allows accurate radiologic and histologic assessment of implant resorption and ingrowth of new bone. PMID- 6928182 TI - Reconstituted collagen xenografts for the repair of oroparanasal defects: an experimental study. AB - An experimental animal model system for reproduction of oroparanasal communications in the guinea pig is reported. Standard clinical closure techniques, both immediate and delayed, are used, as well as a new graft material reconstituted collagen. The clinical and histologic findings are discussed. Results indicate that an oroparanasal defect in the guinea pig can be maintained, that the use of reconstituted bovine collagen as a xenograft to the defect is an aid to closure and contour, and that further study is warranted for eventual application in humans. PMID- 6928184 TI - Nasal endotracheal intubation for outpatient anesthesia. AB - A review of the literature disclosed many potential complications associated with endotracheal anesthesia. A retrospective review of the records of the general anesthetics administered to 5,223 outpatients receiving nasal endotracheal intubation at the Ohio State University was undertaken. This review showed minimal serious complications associated with nasal endotracheal anesthesia used for outpatients. PMID- 6928183 TI - A comparative study of the clinical effects of pentobarbital and diazepam given orally as preoperative medication. AB - The clinical effects of pentobarbital, 100 mg, and diazepam, 10 mg, given orally as preoperative medications before dental surgery were tested in a double-blind study in 50 adult patients. The concnetrations of pentobarbital and diazepam (plus its three active metabolites) in plasma, measured by gas chromatography, were correlated with their clinical effects as assessed both subjectively and objectively (sedation, apprehension, excitement, dizziness, pre- and post operative emetic effect, increase or decrease in systolic blood pressure, pulse rate, and ease of venipuncture). No significant difference in the effects of these two agents was observed, nor was there any obvious relationship between the concentration in plasma and clinical effect. PMID- 6928186 TI - Insidious mandibular metastasis of bronchogenic carcinoma. PMID- 6928185 TI - Maxillary malignant ameloblastoma with intraorbital extension: report of case. AB - The case of an aggressive and malignant ameloblastoma of the maxilla in a 22-year old Nigerian man has been presented. The features that may lead to the development and diagnosis of malignancy in this type of tumor are briefly described and discussed. The relatively young age of this patient, especially in an environment in which medical advice is sought very late, is noteworthy. PMID- 6928187 TI - Treatment of oro-antral-nasal fistula after anterior maxillary osteotomy. AB - A case of a patient with an open bite deformity was presented that, because of improper preoperative treatment planning, resulted in an oro-antral-nasal communication. The subsequent re-evaluation of the patient and the corrective surgical procedure are discussed, with a retrospective evaluation of the total treatment sequence. PMID- 6928188 TI - The superior orbital fissure syndrome: report of case. PMID- 6928189 TI - Parinaud oculoglandular syndrome and cat-scratch fever. AB - The clinician should examine for conjunctival inflammation when preauricular adenopathy exists. Parinaud oculoglandular syndrome is probably caused by many different antigens, including CSD. Biopsy of the affected node is seldom indicated but may be necessary to help rule out neoplastic disease. PMID- 6928190 TI - Ludwig angina, empyema, pulmonary infiltration, and pericarditis secondary to extraction of a tooth. AB - A case of Ludwig angina after extraction of a mandibular third molar, progressing to pleural effusion and empyema, pericarditis, pulmonary infiltration, and pericardial effusion has been presented. The importance of early diagnosis and treatment as well as appropriate antibiotic and surgical therapy have been discussed. The practice of empirically prescribed antimicrobial agents has also been discussed, and the relevance of the organism E corrodans in oral infections has been emphasized. PMID- 6928191 TI - Geriatric nutrition: the role of taste and smell in appetite. AB - Proper nutrition is essential to the health of the oral tissues, and healthy tissues enhance prosthodontic treatment of the elderly. All dentists should be prepared to offer dietary advice to this expanding population. Taste and smell are essential to proper nutrition. In the elderly the peripheral sensory receptors decline, causing the appetite to wane. Taste and aroma are inextricably intertwined in determining the palatability and acceptance of food. For example, during an upper respiratory infection, the olfactory receptors are blocked. Food becomes tasteless; it loses both flavor and aroma and the appetite declines. As a result of aging, the taste buds on the tongue and the olfactory receptors in the roof of the nasal cavity regress. In addition, the gustatory and olfactory nuclei in the brain decline, causing a reduction in appetite and diet. PMID- 6928192 TI - An evaluation of soft tissue responses following removal of ill-fitting dentures. AB - An investigation was conducted on the changes in the thickness of the soft tissues after ill-fitting dentures had been left out of the mouths of 14 subjects for 72 hours. Periapical radiographs were made before and after resting the soft tissues, and the thickness of the soft tissues was measured on the radiographs. A comparison of these measurements showed an average increase of 0.136 mm in thickness of the soft tissues before and after leaving the dentures out of the mouth. PMID- 6928193 TI - Variation in size and form between left and right maxillary central incisor teeth. AB - The evaluation of the collated results demonstrated that 86% to 90% of the subjects examined did not have identical dimensions or form of the left and right maxillary central incisors. In over 60% of these subjects the differences were quite substantial. PMID- 6928194 TI - An evaluation of postadjustment polishing techniques for porcelain denture teeth. AB - Eleven commonly used methods of adjusting and polishing porcelain denture teeth were evaluated. They were compared to the surface of an unaltered denture tooth. Three methods (7, 10, and 11) resulted in surfaces which appeared polished under visual examination. These three methods produced finished surfaces comparable to the unaltered tooth. In attempting to avoid the undesirable sequelae of occlusal wear due to friction, the dentist may choose one of these techniques to complete the adjustment of vacuum-fired porcelain denture teeth prior to placement of the denture. Clinical significance of slight differences in surface roughness must be assessed through carefully controlled patient studies. PMID- 6928197 TI - Surface roughness of two dental amalgams after various polishing techniques. AB - 1. In comparison with standard polishing after 24 hours, no advantage is gained by using an abrasive paste after 10 minutes. Polishing after 24 hours produced a significantly smoother surface for both amalgam alloys on both the simulated proximal and occlusal surfaces. 2. The standard polishing procedures after 24 hours produced a smoother surface than any of the immediate finishing procedures tested. 3. The high-copper amalgam was signijficantly rougher with initial carving and immediate finishing, but surfaces of both alloys were equally smooth when polished after 24 hours. 4. Both amalgam alloys, when condensed against a new matrix band lacked smoothness when compared to the surfaces obtained by finishing after 24 hours. 5. There was a high correlation between arithmetic average roughness and average maximum peak height as quantitative measurements of surface texture. PMID- 6928196 TI - Discrepancies between arbitrary and true hinge axes. AB - Four-hundred forty-four true hinge axis locations were made and compared to various arbitrary locations. Statistical determinations of probability were made from the population sample. It was found that any chosen arbitrary location would not reliably represent the true anatomic hinge axis. PMID- 6928195 TI - An electromyographic study of masticatory and lip muscle function in patients with complete dentures. AB - The activity of the anterior and posterior portions of the temporal muscle, of the masseter muscle, and of the upper and lower lips was studied with electromyography in 10 individuals with complete dentures. Recordings were made when the patients had old, ill-fitting dentures and 6 months after these were replaced with new dentures. The muscle activity was studied in the postural position of the mandible, during chewing and swallowing of three test foods, and during maximal biting. The maximal tooth tapping rate was also recorded. The postural muscle activity was the same with old and new dentures and comparable with that in patients with natural teeth. The muscle activity during maximal biting was markedly lower than in patients with natural teeth and lower with new than with old dentures. There was no difference in muscle activity between chewing with old and new dentures, but the activity was lower than in patients with natural teeth. This was not compensated for by a longer duration of chewing. The lips were not especially active during chewing in the complete denture wearers. PMID- 6928200 TI - Prosthetic support of laryngotracheoplasty for acquired subglottic stenosis in infants and children. AB - Using readily available materials and familiar techniques, prosthetic stents and T-tubes can be made to provide invaluable support in the treatment of subglottic stenosis in infants and children. A method of constructing these stents and tubes has been described along with an explanation of their surgical purpose and use. PMID- 6928199 TI - Modified bypass in maxillary hollow-bulb obturators. AB - A new technique is presented for adding a bypass to an edentulous obturator. Fluids which seep into the defect and nasal secretions may pass to the oral cavity through a diagonal tubing in the obturator. Features of this obturator bypass include: (1) use of 8-gauge wax and autopolymerizing acrylic resin to assure the patency and smoothness of the bypass, (2) beveling of the oral opening and creating a tortuous course for the tube to allow for preservation of intraoral pressure so that speech is not affected, and (3) creation of a funnel where the tube opens on the tissue side of the obturator bulb permitting easy collection of fluids. PMID- 6928198 TI - Self-threading pin penetration into dentin. AB - A laboratory study has shown that the first-half of self-shearing 2-in-1 self threading pins, sizes 0.031 inch and 0.024 inch, fail to reach full channel depth when placed with either a hand wrench or an Auto Klutch handpiece. The average discrepancy of penetration is about 0.75 mm. This discrepancy in seating results in a significant excess pin length extending into the tooth preparation, which compromises the strength characteristics of the amalgam restoration. PMID- 6928201 TI - Radiographic study of condylar position in centric relation and centric occlusion. AB - The present study was conducted to compare the spatial relationship of the condyles to their fossae in the centric occlusion and centric relation positions. Right and left TMJ radiographs were obtained on 40 young adults in the two positions. Direct measurments of the anterior, posterior, and superior spaces between the condyles and their fossae were made on the radiographs. Results were statistically analyzed; the following findings and conclusions were derived: (1) In the centric relation position, both condyles were placed more posteriorly and superiorly in their fossae than in the centric occlusion position. (2) In the centric occlusion position, both condyles were symmetrically placed in their fossae with equal spatial distances anteriorly and posteriorly. (3) Greater spatial differences existed between the centric occlusion and centric relation positions on the left side, which was the orbiting (balancing)side in most subjects. (4) Further studies are needed to develop a more physiologic approach for correctly relating the mandible to the maxillae when reconstructing the occlusion in both dentulous and edentulous patients. PMID- 6928202 TI - Relationship between the temporomandibular joint and pantographic tracings of mandibular movements. AB - Lateral polytomography of the TMJ and pantographic tracings of mandibular movement were performed in 30 patients with TMJ pain-dysfunction syndrome. The condyles were classified as rounded or flattened. The articular eminences were classified as convex or flattened. Two types of immediate side shift, progressive side shift and vertical protrusive tracing, were observed. Type A was curved, Type B was straight. A significant relationship was found between the shape of the TMJ and the tracing pattern. Type A immediate side shift (when present), progressive side shift, and vertical protrusive tracings were more typical of patients with rounded condyles and convex articular eminences. Type B was typical of patients with flattened condyles and, to a lesser extent, flattened articular eminences. Superior displacement of the rotating condyle was found only in patients with flattened condyles. PMID- 6928203 TI - Functional loading of bioceramic augmented alveolar ridge--a pilot study. AB - Two mongrel adult dogs were used in this study. The mandible was edentulated unilaterally and then augmented with porous tribasic calcium phosphate ceramic. To determine the effects of a denture over the augmented site, a unilateral distal-extension removable partial denture was constructed and inserted. At the end of the 6-month period, clinical evaluation revealed a healthy residual alveolar ridge tissue with no inflammatory reaction due to the implant. Histologic examination confirmed the clinical findings. There was no inflammation, bone and soft tissue grew into the pores, and no bone resorption occurred. It is concluded therefore that porous tribasic calcium phosphate ceramic is a potential material for residual alveolar ridge augmentation. PMID- 6928204 TI - Classification of articulators. AB - A simple classification in familiar terms with definite, clear characteristics can be adopted. This classification system is based on the number of records used and the adjustments necessary for the articulator to accept these records. The classification divides the articulators into nonadjustable, semiadjustable, and fully adjustable articulators (Table I). PMID- 6928205 TI - Medical professional liability picture in New Jersey. Potential liability of hospital staff. PMID- 6928206 TI - Riding to death. PMID- 6928208 TI - Surgical treatment of intractable vertigo. PMID- 6928207 TI - Surgical management of perforated diverticulitis of the sigmoid colon. PMID- 6928209 TI - Current stapedectomy update. PMID- 6928210 TI - Mesenteric embolectomy. PMID- 6928211 TI - Spontaneous myocardial cholesterol embolization. PMID- 6928213 TI - Ascorbic acid (Vitamin C) in the treatment of cancer. PMID- 6928212 TI - Pneumonia: a clinical review. PMID- 6928214 TI - Tocainide. PMID- 6928216 TI - Infant formulas. PMID- 6928215 TI - Gossypol as an oral contraceptive for men. PMID- 6928219 TI - Isokinetic gradient sedimentation of normal human bone marrow cells: a simple method for isolation of proliferative granulocytic and erythroid elements. AB - Proliferative granulocytes and erythroid precursors were isolated from cell suspensions of human normal bone marrow by sedimentation on an isokinetic gradient of continuous low-density Ficoll. A fivefold enrichment with a 70% recovery of the proliferative granulocyte cohort and of early erythroid elements was achieved, as determined by differential morphology and tritiated thymidine incorporation. Viability and in vitro proliferative capacity following gradient centrifugation remained intact. This method of cell separation, based on differences in cell diameter, affords a simple and rapid means for the purification of specific cell populations from heterologous human normal bone marrow. PMID- 6928218 TI - Duodenal carcinoembryonic antigen in patients with benign and malignant diseases: preliminary observations. PMID- 6928217 TI - An experimental model of cachexia induced by a xenografted human tumor. AB - A hypernephroma removed from a male patient who had lost 30 kg in weight in the 2 months preceding surgery was established in immunosuppressed CBA/Lac mice as a nonmetastasizing transplantable xenograft. The xenografted tumors, although comprising less than 5% of the total body weight of the mice, produced considerable weight loss (greater than 25%). A slight reduction in food intake of tumor-bearing mice was noted, but some animals bearing mouse or human tumors not inducing cachexia had equally low food intake without accompanying weight losses. No obvious defects in gastrointestinal histology or absorption were observed. The precise mechanism(s) producing the severe cachexia remains to be established. PMID- 6928221 TI - Glucose turnover and gluconeogenesis during hypocaloric glucose infusion in tumor bearing F344 male rats. AB - Glucose turnover ([3(3)H]glucose) and gluconeogenesis from alanine ([U 14C]alanine) were measured in non-tumor bearing (NTB) and tumor-bearing (TB) inbred F344 male rats during starvation and in response to graded levels of glucose infusion. All groups demonstrated a glucose turnover appropriate to the prevailing steady-state plasma glucose level. Whereas NTB animals exhibited maximal suppression of gluconeogenesis from alanine at infusion rates of 0.39 mg/100 g total body weight/minute, TB animals suppressed alanine-to-glucose conversion only at a glucose infusion rate of 0.71 mg/100 g total body weight/minute. Glucose clearance was consistently higher in TB groups but did not change in either NTB or TB groups during infusion. Blood lactate levels increased in response to glucose infusion only in TB animals. These results suggested that starved TB animals obligately utilized more glucose than did NTB controls but were able to adjust turnover appropriately to plasma glucose levels. However, gluconeogenesis was suppressed only at higher glucose infusion rates in TB rats compared to NTB animals. PMID- 6928220 TI - Action of intensive cigarette smoke inhalations on the rat lung. Role of particulate and gaseous cofactors. AB - The action of high doses of cigarette smoke alone or combined with coal dust or acrolein was investigated in noninbred Sprague-Dawley rats. Inhalation occurred up to six sessions per day (Hamburg machine), the animals being subjected to a treatment with oxygen after each inhalation session to reduce the carbon monoxide level in the blood. The amount of tar found in the lungs depended on the number of inhalation sessions per day rather than on the total number of inhalations. Smoke inhalation caused emphysematous lesions, the extent of which depended on the total dose of smoke inhaled. No lung tumors were observed. Only a hyperplasia of the alveolar lining involving type II alveolar cells and, at a later stage, areas of metaplasia generally limited to the bronchial area were found. The association of coal dust with cigarette smoke did not alter the specific effects of smoke and resulted in effects peculiar to the action of dust: alveolitis of the macrophage type, fibrosis of the reticulin type, limited hyperplasia, and ciliated metaplasia. When smoke was combined with acrolein, the effects due to smoke were not appreciably altered. PMID- 6928222 TI - Drug-mediated antigenic changes in murine leukemia cells: antagonistic effects of quinacrine, an antimutagenic compound. AB - Because the antigenic changes occurring after in vivo treatment of murine lymphoma cells with 5-(3,3-dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide (DTIC) were suggested to result from DTIC-induced somatic mutation(s), quinacrine dihydrochloride, an antimutagenic compound, was tested for possible antagonistic activity related to this phenomenon. The increased immunogenicity of L1210Ha leukemia occurring at the first transplant generation of DTIC-treated histocompatible (BALB/cCr x DBA/2Cr)F1 male mice or the appearance of strong lymphoma-associated transplantation antigens at transplant generation 6 was prevented by simultaneous administration of quinacrine. However, the compound did not modify the antitumor or immunodepressive activity of DTIC in the mouse. We concluded that the selective antagonistic effect of quinacrine on DTIC-mediated immunogenic changes (DMIC) supported the hypothesis that the molecular mechanism of DMIC could be related to somatic mutation(s). PMID- 6928223 TI - In vitro cell-mediated cytotoxicity and antibody-dependent cellular cytotoxicity to the transmissible venereal tumor of the dog. AB - Cell-mediated immunity to the transmissible venereal tumor (TVT) of the dog was studied by use of a 51Cr release cytotoxicity assay. Peripheral blood lymphocytes (PBL) of dogs in which the TVT had regressed were shown to be cytotoxic to the tumor cells in contrast to PBL of normal dogs and animals during progressive tumor growth, which were not cytotoxic. In addition, sera of dogs in which the TVT had regressed could be demonstrated to mediate antibody-dependent cellular cytotoxicity (ADCC) with normal dog lymphocytes or cytotoxic PBL as effector cells. With cytotoxic lymphocytes, the ADCC effect could be observed in addition to the direct cytotoxic effect. PMID- 6928224 TI - Intermediate-sized filaments in cultured rat liver tumor cells with Mallory body like cytoplasm abnormalities. AB - The endoskeletal structure of tumor cells with a characteristic cytoplasmic abnormality initiated in rat liver by the in vivo adminisration of the carcinogen diethylnitrosamine was studied in clonal cell lines established and propagated in vitro. The bulk of the cytoplasmic and plasma membrane protein was removed by extraction with Triton X-100, and subsequently the juxtanuclear detergent insoluble fraction containing filaments of 100-150 A was released into citrate buffer at pH 2.8. Analysis of this fraction by sodium dodecyl sulfate acrylamide gel electrophoresis revealed the pressence of five major proteins that banded with apparent molecular weights of about 66, 57, 52, 48 , and 43 x 10(3), the last of which comigrated with actin. The proteins thus resembled those from intermediate-sized filaments of both the vimentin (57 x 10(3)) and the prekeratin types obtained from various vertebrate cells. They also appeared to be related to the polypeptides of intermediate-sized filaments from Mallory bodies induced by griseofulvin in the livers of mice and to some of the polypeptides seen in isolates of Mallory bodies from human alcoholics. These results indicated that a major component of the carcinogen-induced lesion consisted of intermediate-sized filaments. The possible significance in cell transformation of this stably maintained aggregate of filaments that binds concanavalin A and displaces the nucleus is discussed. The close resemblance of this lesion to that seen in the cells of cirrhotic livers of alcoholics (Mallory's alcoholic hyalin) raises a question regarding the possible oncogenic status of such cells in humans. PMID- 6928225 TI - Distinction of normal, preneoplastic, and neoplastic mouse mammary primary cell cultures by water nuclear magnetic resonance relaxation times. AB - Normal, preneoplastic, and neoplastic primary cultures of mouse mammary epithelial cells were distinguishable on the basis of water proton nuclear magnetic resonance (NMR) relaxation times--i.e., spin-lattice relaxation time (T1) and spin-spin relaxation time (T2). T1 values were 916 +/- 24 msec for normal cells, 1,029 +/- 24 msec for preneoplastic cells, and 1,155 +/- 42 msec for neoplastic cells. This method of distinction between normal and neoplastic cells (P less than 0.001) and normal and preneoplastic cells (P less than 0.005) supported previous findings in whole tissues. NMR relaxation times resulted in better distinction between these cell populations than any other technique except direct histology. The T1 and T2 values of water protons in cells grown in primary culture were higher than those of established mouse mammary cancer cell lines. The differences in T1 and T2 did not correlate with cellular hydration. The data suggested a basic difference in water-macromolecular surface interactions among normal, preneoplastic, and neoplastic cells. PMID- 6928226 TI - Opposite effects of different strains or batches of same strain of BCG on in vitro generation of syngeneic and allogeneic antitumor cytotoxicity. AB - Pretreatment of mice with three batches of BCG Phipps strain 10 days before in vitro immunization of their spleen cells with syngeneic or allogeneic tumor cells augmented the levels of antitumor cytotoxicity (compared to the levels exhibited by in vitro immunized spleen cells from normal mice), whereas pretreatment with another batch of BCG Phipps strain or with a batch of BCG Tice strain suppressed antitumor cytotoxicity. The suppressive effects of these BCG vaccines could not be attributed to route of administration, dose of BCG, or percentage of colony forming units in an inoculum. The effect of the interval between BCG pretreatment and in vitro immunization on the generation of antitumor cytotoxicity was evaluated; one BCG batch was of special interest, inasmuch as augmented cytotoxicity was obtained when the interval was short and suppressed cytotoxicity was obtained when the interval was long. PMID- 6928227 TI - Binding of radioactivity after transplacental administration of tritiated N nitrosodiethylamine to Syrian golden hamsters. AB - Tritiated N-nitrosodiethylamine (DEN) was administered to two groups of female Syrian golden hamsters on days 11 and 15 of pregnancy. Binding of radioactivity was measured in maternal and fetal organs after various intervals by liquid scintillation counting of dehydrated and combusted tissues. No bound activity was found in the fetal tracheas on day 11 of gestation, when transplacental administration of DEN is known to be noncarcinogenic for the offspring. On day 15, when DEN administration caused a 95% incidence of tracheal tumors in the offspring, bound radioactivity was found in the fetal tracheas. In the respiratory tracts of the mothers, the distribution of bound radioactivity correlated with the distribution of target cell types. Binding was high in segmental bronchi and bronchioles which contain numerous Clara cells, the major source of DEN-induced pulmonary tumors. No binding occurred in the main bronchi, which do not possess Clara cells. PMID- 6928228 TI - Requirement of essential fatty acids in the diet for development of the mouse mammary gland. AB - The ductal system of mammary glands in C3H mice that were started on diets deficient in essential fatty acid(s) (EFA) 1--2 weeks after weaning developed at a normal rate. The alveolar structures, however, began to disappear in the mice after 17 weeks on the EFA-deficient regimen. Injection sc of linoleic acid prevented the atrophic process. Alveoli were also absent in the glands of multiparous mice that were maintained for 32 weeks on the EFA-deficient diet. When the EFA-deficient regimen was started in females during midpregnancy and maintained continuously thereafter, both ductal and alveolar structures failed to develop in the mammary glands of the offspring. Linoleic acid appears to be required for development of ductal and alveolar structures during growth of the mammary gland and also for maintenance of the alveolar structures in the adult mammary gland. PMID- 6928229 TI - Chronic inhalation of cigarette smoke by F344 rats. AB - Specific-pathogen-free female F344 rats were exposed by inhalation to what was considered a maximal tolerated dose of cigarette smoke. Total pulmonary deposition of smoke particulates from a single cigarette was 0.25 mg in young rats. Rats were exposed to smoke from 7 cigarettes/day for as long as 2.5 years, at which time 30% of the rats remained alive. Mortality of smoke-exposed animals was not different from that of untreated or sham-exposed controls. Hyperplastic and metaplastic areas in the epithelium of the nasal turbinates, larynges, and tracheae of exposed animals were observed at death. The lungs of exposed rats contained areas of focal alveolitis consisting of accumulated pigmented macrophages, epithelial hyperplasia, fibrosis, and disrupted alveolar structure. Smoke exposure did not change the total number of tumor-bearing animals relative to controls; however, exposed rats had significantly fewer tumors in the hypophyses, hematopoietic-lymphoid systems, uteri, and ovaries but an increased number of tumors in the respiratory tracts and dermes. Only 1 of 93 (1%) control rats had a tumor (an alveologenic carcinoma) in the respiratory tract as opposed to 7 of 80 (9%) exposed animals (nasal tumors: 1 adenocarcinoma and 1 squamous cell carcinoma; pulmonary tumors: 5 adenomas, 2 alveologenic carcinomas, and 1 squamous carcinoma). PMID- 6928232 TI - For rationality in radiation risk studies. PMID- 6928230 TI - Anticancer agents and antitrypanosomiasis activity in mice. AB - Of 303 compounds (66 active against cancer and 237 inactive against cancer) obtained from the Drug Synthesis and Chemistry Branch, Developmental Therapeutics Program, Division of Cancer Treatment, National Cancer Institute, Bethesda, Maryland, 25 were found to be active against Trypanosoma rhodesiense infections of ICR/Ha Swiss mice. Fifteen of these 25 compounds also had anticancer properties. The percentage of anticancer compounds found to have antitrypanosomiasis properties was 22.7. This percentage compares with 6% antitrypanosomiasis compounds among compounds selectecd by other methods. PMID- 6928231 TI - Relationship of hormone dependency to estrogen receptor and adenosine 3',5' cyclic monophosphate-binding proteins in rat mammary tumors. AB - Estrogen-binding activity and the binding activity of adenosine 3',5'-cyclic monophosphate (cAMP) were assayed in the cytosol of biopsy specimens from 70 rat mammary tumors. The response of these tumors to host ovariectomy was followed. The hormone dependency of the tumors was closely related to the relative concentrations of estrogen receptor (ER) and cAMP-binding protein (CR) in the tumor cytosol. When ER and CR were expressed as the ER/CR ratio, 36 of 38 (95%) hormone-dependent tumors had ratios of 35 X 10(-3) or more, whereas 31 of 32 (97%) hormone-independent tumors had ratios of less than 35 X 10(-3). When ER alone was measured, hormone dependency could be correctly predicted in only 60% of the tumors because the ER range for individual tumors of both types greatly overlapped. Ratios of ER/CR were also elevated in normal estrogen target tissues as compared to those in normal estrogen nontarget tissues. Thus determination of the ER/CR ratio in tumor cytosols appeared to be a more reliable method of predicting hormone dependency than was determination of ER alone. PMID- 6928233 TI - N,N-dimethylformamide-induced modulation of organ- and tumor-associated markers in cultured human colon carcinoma cells. AB - Cultured human colon carcinoma cells were induced by the polar solvent N,N dimethylformamide (DMF) to express a more differentiated phenotype as indicated by three types of antigen markers. Carcinoembryonic antigen expression in all DMF induced cell lines was enhanced. Exposure of cells to DMF resulted in a reduction in ability to bind antibody to tumor-derived colon mucoprotein antigen (CMA) with a concomitant gain in binding of antibody to normal CMA. DMF-induced differentiation was further indicated by modulation of blood group antigen expression. DMF treatment decreased the amount of expression of the H-gene determinant. When DMF-treated cells were cultured in the absence of DMF for 14 days, the levels of expression of the antigen markers reverted to those characteristic of their untreated counterparts. PMID- 6928234 TI - Changing ratio of breast cancer incidence rates with age of black females compared with white females in the United States. AB - Age-standardized breast cancer rates were approximately 30% lower in U.S. black women compared to white women. This observation concealed the fact that black women under age 40 years had a higher incidence of breast cancer than did white women, whereas white women over 40 years had a higher incidence. The known risk factors for breast cancer development (early age at menarche, late age at first full-term delivery, and a late age of menopause) differed in black and white populations, which might explain this difference in breast cancer incidence between blacks and whites at different ages. PMID- 6928235 TI - Chromosome evolution of near-haploid clones in an established human acute lymphoblastic leukemia cell line (NALM-16). AB - A cell line has been established from blood lymphoblasts of a female patient with acute lymphoblastic leukemia (ALL) shown to have near-haploid (27 chromosomes) cells in the bone marrow. The findings about the cell line were: 1) The frequency of near-haploid cells in culture decreased with time from 98.2% when the culture was started to 5.4% 15 months later. 2) Most of the other cells except the near haploid ones were hyperdiploid, i.e., duplicates of the cells with near-haploid chromosome constitutions. 3) Chromosome evolution was seen in the near-haploid clones. The possible ancestor clone (clone A) had 27 chromosomes, one of each pair except no.10, 14, 18, and 21, which were disomic. A suggested evolution process is: clone A yields clone B (26 chromosomes: clone A, -no.10) yields clone C (27 chromosomes: clone B, +X) yields clone D (26 chromosomes: clone C, -no.21), clone E (28 chromosomes: clone C, +NO.20). Clone B and D, each with 26 chromosomes, appeared to contain the lowest number of chromosomes, appeared to contain the lowest number of chromosomes ever described for human somatic cell clones in vitro. 4) Changes in the constitutions of the hyperdiploid cell clones were preceded by evolution and changes in the near-haploid clones. 5) In near haploid cells with 2 X-chromosomes, 1 exhibited late DNA replication; in hyperdiploid cells with 3-5 X-chromosomes, 2 were non-late DNA-replicating. 6) Fresh (uncultured) and cultured leukemia cells were antigenically typical non-T, non-B or common type ALL cells (positive for la-like and null-type ALL antigens and negative for surface membrane immunoglobulin). PMID- 6928236 TI - Tumor incidence and development of autoimmune hemolytic anemia in two breeding lines of the NZB mouse strain that differ in chromosome breakage. AB - Increased chromosome breakage observed in NZB mice was studied. Breeding experiments with mice selected according to breakage frequencies provided evidence that the proportion of mice with high breakage (HB) and low breakage (LB) figures in the progeny depends on the phenotype of the parents. Selective breeding for the "chromosome breakage" characteristic was successful and resulted in the separation of a breeding line with LB incidence. However, the selection could not be continued beyond the fourth generation for the mice with HB incidence because of lethal factors. Comparative studies of HB mice from the HB line and LB mice from the LB line showed significant differences for tumor incidence and positivity of the Coombs' test. PMID- 6928237 TI - N-nitroso-2,6-dimethylmorpholine-induced hemangiosarcomas in the livers of randombred guinea pigs. AB - The carcinogenic effect of N-nitroso-2,6-dimethylmorpholine (DMNM) was studied in randombred guinea pigs after repeated administration of this compound by gavage. DMNM was administered at two dose levels (14 and 28 mg/kg body wt) weekly for 23 weeks. All animals were observed until their death or termination of the experiment at 54 and 37 weeks for the 14- and 28-mg dose levels, respectively. At 14 mg, 67% of the animals developed hemangiosarcomas of the liver and 60% developed cholangiomas between 36 and 54 weeks. In addition, a poorly differentiated malignant mesenchymal tumor was observed in 1 animal. At 28 mg, liver hemangiosarcomas were observed in 82% of the animals between 26 and 37 weeks. In addition, in 18% of the animals, bronchioalveolar adenoma (1 animal), hepatocellular carcinoma (1 animal), and malignant lymphoma (1 animal) were also induced. Metastases of hemangiosarcomas to lungs, mesenteries, and lymph nodes were observed in 3 animals of each group. PMID- 6928238 TI - Relationship between dimethylnitrosamine metabolism or activation and its ability to induce liver necrosis in rats. PMID- 6928239 TI - Growth stimulation of BHK cells in culture by free biotin in serum. AB - A dialysate of fetal bovine serum stimulated the growth of BHK cells in a medium containing 1% dialyzed serum. The growth-stimulating activity of the dialysate was separated in a single peak with Biogel P-2 chromatography, and a single active component was further fractionated with paper and thin-layer chromatography. The component was identified as biotin. Pure biotin behaved the same as the active component in the dialysate and had the same growth-stimulating activity. The dialysate contained only the free biotin that was present in serum. Free biotin was found in relatively large amounts in fetal (bovine and human) sera, and only a very small percentage of dialysates of adult (bovine, horse, swine, and human) sera had traces of growth-stimulating activity. The possible role of free biotin in the body is discussed. PMID- 6928240 TI - Immunotherapy of murine leukemia. II. Effect of passive serum therapy on Friend murine leukemia virus-induced hematologic and coagulation parameters. PMID- 6928241 TI - Toxicity of nitro compounds toward hypoxic mammalian cells in vitro: dependence on reduction potential. AB - Fifteen nitroaromatic and nitroheterocyclic compounds that can act as "radiosensitizers" were tested for their cytotoxicity toward hypoxic Chinese hamster V79 cells in vitro. The cytotoxicity increased markedly as the electron affinity, measured as a one-electron reduction potential, increased. Non-nitro containing compounds of similar electron affinities (such as quinones) that also act as radiosensitizers did not exhibit this specific toxicity toward hypoxic cells. The implications of the presence of the nitro group as a prerequisite for the hypoxic cell toxicity were discussed, and the mechanism of the cytotoxicity was compared with that of hypoxic cell radiosensitization. PMID- 6928242 TI - Experimental colon cancer in the absence of intestinal contents in Sprague-Dawley rats. AB - The proximal and distal ends of the transverse colons of 16 noninbred Sprague Dawley rats were severed and stitched to their abdominal walls. The ascending and descending colons were anastomosed end-to-end. The disarticulated colon loop was rinsed 30 times over 15 days to remove all traces of dimethylhydrazine (21 mg/kg body wt) for 27 weeks. When rats were killed 3 weeks later, 4 had invasive carcinomas and 2 had tubular adenomas in the end-to-end anastomosed (function isolated) colons. Three rats developed invasive carcinomas in the isolated (defunctionalized) colon loops. The carcinogen probably reached the isolated colon loop through the circulation and induced (independently of bile acids) mucosal changes that led to invasive carcinoma. PMID- 6928243 TI - Effect of cholic acid feeding on N-methyl-N-nitrosourea-induced colon tumors and cell kinetics in rats. PMID- 6928244 TI - A new mouse tumor model system (RIF-1) for comparison of end-point studies. AB - A new tumor model system (RIF-1) was developed that is very suitable for studies in which clonogenic survival is compared with growth delay and control probability following various forms of treatment. The tumor was a radiation induced sarcoma in the inbred female C3H/Km mouse. It had a low median tumor dose, had a satisfactory plating efficiency direct from in vivo to in vitro, was nonimmunogenic or minimally immunogenic, and metastasized only at a relatively advanced stage of growth. The cell line grew either as a monolayer on plastic dishes, as tumor spheroids in spinner culture, as lung nodules following injection of a single-cell suspension into the tail veins of syngeneic mice, or as a solid tumor. Both diploid and tetraploid clonogenic cells were found in monolayer cultures of the RIF-1 line. PMID- 6928245 TI - Response to the RIF-1 tumor in vitro and in C3H/Km mice to X-radiation (cell survival, regrowth delay, and tumor control), chemotherapeutic agents, and activated macrophages. AB - The radiation response of logarithmic growth phase and fed plateau phase RIF-1 cells in vitro was found to be characterized by D0 (slope of cell survival curve on semilog plot) values of 110 and 133 rads and extrapolation numbers of 36 and 28, respectively. The response of the tumor in vivo to X-irradiation in nonanesthetized mice showed a dependence on the tumor implantation site. In the leg muscle, the response indicated that most cells were at an intermediate level of oxygenation, whereas in the subcutaneous tissue of the flank, the response of the tumor indicated that it had a small fraction (1.5%) of hypoxic cells of maximum radioresistance. Misonidazole radiosensitized the leg-implanted tumor as measured both by cell survival and regrowth delay. The median tumor cure dose of radiation in mice was 3,990 rads (3,670--4,340), which agreed closely with that predicted from the radiation survival curve. The tumor was relatively insensitive to a single dose of 1,3-bis(2-chloroethyl)-1-nitrosourea, sensitive to a single dose of cis-platinum, and highly sensitive to a single dose of cyclophosphamide. PMID- 6928246 TI - Induction of duodenal tumors in F344 rats by continuous oral administration of N ethyl-N-nitrosourea. AB - Forty male and 40 female inbred F344 rats were given a solution of 400 mg N-ethyl N-nitrosourea/liter in their drinking water. Digestive tract tumors were induced in 32 males (an incidence rate of 80%) and in 28 females (an incidence rate of 70%). Among these digestive tract neoplasms, duodenal tumors occurred most frequently. Most were of the epithelial type, such as adenoma or adenocarcinoma. Tumors in hematopoletic organs were also found in 15 males (38% incidence) and in 17 females (43% incidence). PMID- 6928247 TI - Effect of dietary fat on X-ray-induced mammary cancer in Sprague-Dawley rats. AB - We studied the effect of dietary fat levels on the induction of mammary cancer by 350 rads total-body X-radiation given to noninbred albino Sprague-Dawley rats at 50 days of age. Compared to rats on a low-fat (LF) diet (5% lard), rats on a high fat (HF) diet (20% lard) from 30 days of age had more tumors, with a higher multiplicity of carcinomas per rat. LF-fed groups exhibited a longer median tumor latency period thatn did HF-fed groups. A similar trend toward more tumors with an earlier time of death was seen in rats given single iv doses of 50 mg 1-methyl 1-nitrosourea/kg and fed an HF diet as compared to an LF diet. PMID- 6928248 TI - Differential inhibition of in vitro malignant cell assays by B16 mouse melanoma variants. AB - Neural retina aggregation and adhesion assays, shown to be sensitive to the presence of small number of malignant cells, were differentially inhibited by cells or medium from B16 mouse melanoma sublines with higher metastatic characterizations, which suggests a correlation between inhibition of adhesion and aggregation and metastatic potential. PMID- 6928249 TI - Effect of retinyl acetate on the incidence of mammary carcinomas and hepatomas in mice. AB - Studies were designed to determine the efficacy of retinyl acetate (RA) in preventing mammary tumorigenesis in C3H-Avy female mice. Mice were fed a stock diet supplemented with RA beadlets at concentrations of 83, 41, and 21 mg/kg diet. Control animals received stock diet supplemented with placebo beadlets. The RA diet was started at conception in 1 group of animals whose mothers were fed RA from the time of mating. Two other groups of animals were placed on the RA diet at weaning or at 3 months of age. Mice were killed and necropsied 1 month after the appearance of the first mammary tumor or at 15 months of age if no tumor developed. No significant difference in incidence of mammary carcinomas was found between control and RA-fed mice. The incidence was 80--90% in all groups. The number of tumors per mouse (1.6--2.1) and the tumor latency period (10.2--11.6 mo) were not influenced by RA in the diet. Two unexpected observations were made: 1) Control mice autopsied at 12 months of age or older showed a 70% incidence of hepatomas, whereas the incidences were approximately 11, 17, and 46% in mice fed 83, 41, and 21 mg RA/kg diet, respectively. 2) Severe damage to most articulations was induced by RA, even at the dose of 21 mg/kg diet, which failed to cause any other sign of toxicity. PMID- 6928250 TI - Growth kinetics of mammary tumor 13762 in rats previously cured by chemotherapy. AB - We studied the growth capabilities of mammary tumor 13762 transplanted into inbred F344 rats previously cured of tumors by cell kinetically based sequential chemotherapy. Of the 18 challenge tumors, 4 were completely rejected, and nonrejected tumors grew at subnormal rates. The subnormal growth was specific for the cured rats because tumor growth in age- and therapy-matched non-tumor-bearing controls was normal. Cell kinetic studies with the use of in vitro techniques for the [3H]dThd labeling index, DNA synthesis time, and primer-dependent DNA polymerase labeling index (an in vitro estimate of growth fraction) indicated that the subnormal growth rates of the 13762 tumor in cured rats were due to subnormal tumor cell production. Cell loss rates were similar in tumors growing in cured rats and in size-matched tumors growing in normal controls. The results are consistent with the possibility that the subnormal growth of 13762 challenge tumors in chemotherapeutically cured F344 rats was mediated by immune factors. PMID- 6928251 TI - Some biological characteristics of transplantable lines of mouse adenocarcinomas of the colon. AB - During a 5-year period colon tumors induced by 1,2-dimethylhydrazine dihydrochloride treatment in NMRI mice were transplanted sc into isologous mice to obtain transplantable tumor lines that might serve as experimental models for human colon cancer. The resultant 17 serially transplantable tumor lines were adenocarcinomas varying in degree of differentiation and mucin production. Two of the lines passaged for 5 years and used in chemotherapy studies have shown histologic progression toward dedifferentiation with concomitant acceleration of growth rate. PMID- 6928253 TI - Respiratory complications in patients with severe burns. PMID- 6928254 TI - Hypothermia in clinical practice. PMID- 6928252 TI - The role of the vascular laboratory in the diagnosis of arterial insufficiency. PMID- 6928255 TI - Radiofrequency thermo therapy for cancer. PMID- 6928256 TI - Lithium and acute monocytic leukemia. PMID- 6928257 TI - A monoclonal antibody to human acute lymphoblastic leukaemia antigen. AB - Previous studies by Greaves and others have demonstrated the existence of an antigen associated with cells from many patients with acute lymphoblastic leukaemia (ALL) and some patients with chronic myelocytic leukamemia (CML) in blast crisis. Antisera to this common ALL antigen (CALLA) have been produced in rabbits and require extensive absorption which limits both the titre and quantity of antisera that can be generated and may result in variable specificity in different laboratories. The method for generation of specific antibody by somatic cell hybridisation introduced by kohler and Milstein has been successfully used to produce monoclonal antibodies against various normal human cell-surface proteins, including beta 2 microglobulin, histocompatibility antigens, thymocyte and peripheral T-cell antigens and Ia-like antigens. The present report describes the generation and characterisation of a monoclonal antibody specific for a common ALL antigen (CALLA) previously identified by conventional heteroantisera. PMID- 6928258 TI - Terminal differentiation in human promyelocytic leukaemic cells in the absence of DNA synthesis. PMID- 6928259 TI - A health care home for the deaf child. PMID- 6928261 TI - Casting alloys. PMID- 6928260 TI - [Current pathogenetic and therapeutic concepts concerning priapism]. PMID- 6928262 TI - The art and science of diagnosis. PMID- 6928263 TI - Children's Dental Health Week 1980. PMID- 6928265 TI - Kerr outlines plans for "access program". PMID- 6928264 TI - DAT program in N.Y. to continue. PMID- 6928266 TI - California program aids senior citizens. PMID- 6928267 TI - NHS dentists flourish in assigned locations. PMID- 6928268 TI - Women in health careers increasing. PMID- 6928269 TI - What price gold? PMID- 6928270 TI - Research methodology in oral diseases. PMID- 6928272 TI - On restructuring the DSSNY. PMID- 6928271 TI - Tissue management during crown and bridge procedures. PMID- 6928273 TI - General anesthesia article stirs up profession. PMID- 6928274 TI - DSSNY and chemical company challenge anti-fluoridation ad in Cortland paper. PMID- 6928275 TI - Survey of DSSNY members' attitudes towards peer review. PMID- 6928276 TI - It begins with one tooth. PMID- 6928277 TI - Division of professional conduct investigates advertising complaints from DSSNY. PMID- 6928278 TI - Council on Dental Care Programs responds to challenge of increasing interest in dental prepayment plans. PMID- 6928279 TI - A histologic evaluation of bone response to bur cutting with and without water coolant. AB - Thirty-six bony cuts were made in the lateral aspect of the mandibles of mongrel dogs. Irrigation was employed in eighteen cuts, while the remaining eighteen were cut without irrigation. Histologic specimens were obtained at 1 hour, 1 day, 3 days, 1 week, and 3 weeks. Early specimens showed marked clot retraction from the bony walls in the nonirrigated cuts, while irrigated cuts demonstrated more firmly adherent and better organized clots. In later specimens, bone formation was less mature in the defects made without irrigation. Inflammation and necrosis of bone were minimal or absent in all sections. Defects made without irrigation exhibited delayed healing in this study. PMID- 6928280 TI - Short-face syndrome: treatment of myofascial pain dysfunction by maxillary disimpaction. PMID- 6928281 TI - Chronic sclerosing osteomyelitis: treatment considerations in an atypical case. AB - Chronic sclerosing osteomyelitis has been frequently described in the literature but little has been recommended for the management of the resistant cases that fail to respond to conservative treatment. This report describes the long term management of a particularly aggressive case of CSO and indicates maxillary sinus disease as a possible etiologic factor in CSO of the maxillary alveolus. Treatment required in more extensive cases must be as aggressive as dictated by the entire disease process and the total medical evaluation. PMID- 6928282 TI - Candidal infections:experience in a British dental hospital. AB - Laboratory and clinical records for a period of 12 months were studied to determine the number of patients investigated for a Candida-related disorder. Of the specimens received from 146 patients, eighty-eight yielded Candida on direct culture and a further twelve isolations were made from Sabouraud's enrichment broth. Smears stained with periodic acid-Schiff reagent gave fewer positive results than culture. Denture stomatitis and angular cheilitis were most commonly encountered; 69% and 77%, respectively, yielded Candida on culture. Staphylococcus aureus was isolated from 28% of the cases of angular cheilitis. Other forms of candidosis were less frequently encountered but yielded Candida more reliably on culture. Ninety-five patients received anticandidal therapy, and 56% showed clinical improvement within 1 month; 13% of the treated patients required treatment for more than 1 year. PMID- 6928283 TI - Systemic complications with intravenous diazepam. AB - There are few published reports of complications following intravenous diazepam administration. However, more than 200 cases were reported to the United States Department of Health, Education and Welfare during a 7-year period. The systemic complications have been categorized by the authors, and common contributing factors are emphasized. The information obtained from these reports provides further knowledge of both the avoidance and the treatment of such complications and emphasizes the importance of reporting the adverse effects of any drug to a central body. PMID- 6928284 TI - Granulomatous gingival manifestations of Melkersson-Rosenthal syndrome. AB - Of thirty patients with complete or incomplete forms of Melkersson-Rosenthal syndrome, five patients with gingival lesions that microscopically showed the characteristic granulomatous changes are presented, with special reference to their gingival manifestations. In some cases bluish red, small, distinct, and irregular edematous swellings characterized the gingival changes, while in other cases more extensive and diffuse, edematous swellings dominated. All five patients had only vague symptoms from the gingiva. Because of the apparent slowly progressing nature of the gingival swellings and occasional spontaneous regression of the gingival changes, a conservative attitude in the treatment of gingival lesions in MRS is recommended. Gingival symptoms may be the first manifestation of the disease, and it is emphasized that, with an increased diagnostic awareness, gingival involvement may be found more commonly in patients with MRS. PMID- 6928285 TI - Amalgam pigmentation (amalgam tattoo) of the oral mucosa. A clinicopathologic study of 268 cases. AB - A series of 268 cases of amalgam tattoo is analyzed both clinically and histologically. The most common location was the gingiva and alveolar mucosa, followed by the buccal mucosa. Histologically, the amalgam was present in the tissues as discrete, fine, dark granules and as irregular solid fragments. The dark granules were arranged mainly along collagen bundles and around blood vessels. They were also associated with the walls of blood vessels, nerve sheaths, elastic fibers, basement membranes of mucosal epithelium, striated muscle fibers, and acini of minor salivary glands. Dark granules were also present intracellularly within macrophages, multinucleated giant cells, endothelial cells, and fibroblasts. Although in 45% of the cases there was no tissue reaction to the amalgam, in 17% there was a macrophagic reaction and in 38% there was a chronic inflammatory response, usually in the form of a foreign body granuloma, with multinucleated giant cells of the foreign body and Langhans types. Asteroid bodies were also found in some of the foreign body giant cells. PMID- 6928286 TI - Gingival myiasis caused by Diptera (sarcophaga). AB - A unique case of true and accidental gingival myiasis caused by Diptera, Sarcophaga (flesh fly, housefly) is reported. Clinical findings are presented and a possible etiology is discussed. PMID- 6928289 TI - Endodontic management of extensive internal root resorption. Report of a case. AB - Often management of unusual cases will require some deviation from standard treatment techniques. The purpose of this article is to describe a case involving extensive internal root resorption. A technique for obturation is described which is a departure from conventional methods presently in use. PMID- 6928288 TI - Comparison of endodontic measurement controls using a paralleling technique with a grid and a conventional measurement. AB - Pretreatment radiographs were taken using a paralleling device and measurement grid. The measurement controls obtained in that manner in 60 teeth were compared to measurements obtained from conventional radiographs taken during endodontic treatment. This study was undertaken to test the proposal that pretreatment radiographs taken with a paralleling device and measurement grid would make further radiographs for that purpose unnecessary, thus reducing patients' exposure to ionizing radiation. PMID- 6928290 TI - Quantitative bacteriology of endodontic infections. AB - A technique is described for obtaining quantitative cultures of endodontic specimens. Paper point samplings were placed in a diluted salt solution, vortexed, and then cultured quantitatively using serial dilutions plated onto multiple media. Specimen weight was determined by weighing the point before and after specimen collection. This method was used in 10 nonvital teeth and showed a mean concentration of 10(7.7) bacteria per gram of sample. Nine specimens yielded a mixed aerobic-anaerobic flora, and there was an average of five different bacterial species per specimen in concentrations exceeding 10(5)/gm. PMID- 6928287 TI - Verrucous carcinoma arising in an odontogenic cyst. Report of a case. AB - A verrucous carcinoma arising in an odontogenic cyst is described for the first time. The clinical, radiographic, and microscopic features of this tumor are presented. It is mandatory to correlate the clinical and histopathologic findings to establish a diagnosis. PMID- 6928291 TI - Effect of temperature on collagen-dissolving ability of sodium hypochlorite endodontic irrigant. AB - The collagen-dissolving ability of both 2.6% and 5.2% sodium hypochlorite endodontic irrigating solutions was compared at room temperature (21 degrees C) and body temperature (37 degrees C). The 2.6% sodium hypochlorite solution at a temperature of 37 degrees C. was found to be equally effective as a collagen dissolving agent when compared to 5.2% sodium hypochlorite at either 21 degrees C. or 37 degrees C. PMID- 6928293 TI - Tomography of the alveolar process. AB - This radiologic study using hemisected dog jaws was undertaken to determine whether or not tomographic techniques would be superior to standard dental x-ray techniques in detecting prepared periodontal defects within the cancellous bone of dog jaws. Specifically, it was done to determine whether or not tomography might be a reliable method of checking for bone fill in periodontal bone-grafting therapy. As an additional measure, a radiographic study, using a hemisected dog mandible and standard dental x-ray techniques, was undertaken to determine whether lesion size or cortical plate involvement was the determining factor in radiographic visibility. When tomographic techniques were used 55% of thirty-one prepared defects were visible, while standard dental x-ray techniques detected 29% of the same defects radiographically. The differences in detection rate were not statistically significant when analyzed by chi square. Although tomography resulted in radiographic visibility of a greater number of prepared defects, it is not reliable enough to replace re-entry procedures for documentation of bone fill in clinical studies of periodontal bone-grafting procedures. In the additional study it was determined that cortical plate involvement was the determining factor in radiographic visibility of bony defects. PMID- 6928294 TI - Internal resorption of four bony impacted third molars. PMID- 6928292 TI - Xeroradiography for intraoral dental radiology. A process description. AB - A novel x-ray imaging system for intraoral dental radiography is described. The imaging process is based on xeroradiographic principles. The surface of a small selenium photoreceptor is electrically charged. After insertion into a light tight cassette, the photoreceptor is placed intraorally and x-ray exposed like film. The resultant electrostatic charge image is developed in a processor using liquid toner. The toner image is then transferred from the photoreceptor and fixed to a white plastic substrate for viewing. After cleaning, the photoreceptor is available for reuse. In contrast to film images, xeroradiographic images are exposed and processed sequentially. Processing time is approximately 20 seconds. Two image characteristics--edge enhancement and deletion--are primarily responsible for many advantageous qualities of xeroradiographic images over film images. An experimental processor was tested successfully at two dental schools. PMID- 6928295 TI - Pseudotranspositioning. PMID- 6928296 TI - Resorption of permanent teeth. PMID- 6928297 TI - The relationship between dental disease and radiation necrosis of the mandible. AB - Preirradiation panoramic radiographs of forty-six dentate patients were examined for the presence of significant dental disease. The occurrence of necrosis of the mandible after these patients received radiation therapy was then determined. Evidence of a positive association between dental disease present before radiation therapy and subsequent necrosis of the mandible was found (p = 0.09), leading to a recommendation that significant disease be eradicated before irradiation of oral tissues. Two cases are reported to illustrate the complications that can arise in dentate patients following radiation to the oral cavity. Considerable suffering results from bone necrosis, which can be reduced by careful and rational dental diagnosis and treatment. PMID- 6928298 TI - Painful traumatic neuromas in the oral cavity. AB - Traumatic neuromas in facial pain are characterized by a history of surgery at time of onset and by pain of an atypical neuralgic or nonneuralgic type with a stinging, burning, or paresthetic character. Pressure on the suspected area provokes pain, and localized analgesia relieves the pain. In six cases out of seven diagnosed clinically according to these criteria, excision biopsy revealed traumatic neuroma. One week postoperatively all patients were improved. One to 3 years later four patients out of six were still satisfactorily improved. In cases of painful oral traumatic neuromas where conservative measures have failed, a single excision then seems justified. PMID- 6928299 TI - Atypical odontalgia. A report of twenty-two cases. AB - The findings in twenty-two cases of a condition that causes pain in the teeth and gingivae are presented. Two cases are described in detail. The importance of recognizing the problem and avoiding unnecessary dental treatment is stressed. The most effective treatment appears to be reassurance and the use of antidepressant drugs. PMID- 6928300 TI - The prevention of contamination of teeth stored for transplantation. AB - Tissue culture media and their application to the storage of teeth are described. The problems of contamination in culture and a method of achieving a sterility level of 73 percent are discussed. Contamination was reduced at each stage, using unerupted teeth, chlorhexidine disinfection, saline irrigation, ultrasonics, a laminar-flow cabinet, and four antibiotics in culture. A method of microbiologic screening is outlined. PMID- 6928301 TI - Bilateral low condylectomy of the mandible. AB - The operation of low condylectomy of the mandible is seldom performed bilaterally. The indications and consequences are reviewed, and a case is reported in which the adverse sequelae commonly attributed to this procedure were avoided over an 11-year follow-up period. PMID- 6928303 TI - Tuberous sclerosis with nonhydantoin gingival hyperplasia. Report of a case. AB - A case of gingival hyperplasia in a subject suffering from tuberous sclerosis who had never received hydantoin for the control of epilepsy is presented. The site and extent of the gingival enlargement differ from that previously reported, and the condition recurred following gingivectomy. PMID- 6928302 TI - An endodontic silver point in the maxillary sinus. Report of a case. AB - During routine clinical examination, a radiopaque needlelike foreign body was disclosed in a patient's left maxillary sinus. The foreign body was surgically retrieved and found to be a bent endodontic silver point. PMID- 6928306 TI - Histopathologic spectrum of oral erythema multiforme. AB - The histopathologic tissue patterns found in twenty-five patients with oral erythema multiforme were as variable as the clinical appearances. The biopsies served an important role in ruling out malignancy, dysplasia, and other classified diseases. While all of the specimens were designated as showing nonspecific inflammatory reactions, in many biopsy specimens there were sufficient characteristic connective tissue and epithelial changes to suggest a tissue diagnosis consistent with the clinical diagnosis of erythema multiforme. PMID- 6928304 TI - The threat of hepatitis B from dental school patients. A one-year study. AB - A study was conducted at the Louisiana State University School of Dentistry using the radioimmunoassay technique of serum analysis for presence of hepatitis B surface antigen (HBsAg) in all new patients accepted for treatment over a period of one year. The prevalence was 0.61 percent (22 seropositive patients from a total of 3,626 patients screened). Chronic HBsAg carriers, presence of e antigen, and high titers of antibody to hepatitis B core antigen (anti-HBc) were documented. Eighteen of the 22 seropositive patients had no past history of hepatitis, indicating the inadequacy of a history for revealing carriers of HBsAg. PMID- 6928307 TI - Salivary gland neoplasia: an outcome of modified morphogenesis and cytodifferentiation. AB - Regeneration and replenishment of salivary tissues proceed in a manner analogous to stages in the embryonic development of salivary glands. The regenerative potential of the salivary unit resides in the reserve or stem cells of the intercalated and excretory ducts. Neoplastic development in salivary glands may be regarded as an epigenetic event, imposed by an ocogenic stimulus onto morphogenesis and cell differentiation. Depending on the level of differentiation of the reserve cell's progeny at the time of oncogenesis, the corresponding neoplasm can be poorly differentiated or anaplastic or as well differentiated as a histologically low-grade acinous cell carcinoma. PMID- 6928305 TI - Salmonella typhi facial infection. Report of case. AB - The following case report describes the evaluation, assessment, and treatment of a facial infection due to Salmonella typhi, caused by bites from the family's pet dog. The causative agent and the mode of transmission are unique in that there are no reported cases of this nature in the literature at this time. PMID- 6928308 TI - Necrotizing sialometaplasia in a patient with Buerger's disease and Raynaud's phenomenon. AB - This report describes a case of necrotizing sialometaplasia (NS) in a patient diagnosed as having Buerger's disease with secondary Raynaud's phenomenon. The danger of misdiagnosing NS as a malignant lesion is emphasized. Possible causal relationships between the patient's medical condition and the lesion are discussed. PMID- 6928309 TI - Clinical and radiobiologic features of Thorotrast-induced carcinoma of the maxillary sinus. A case report. AB - This is a case of Thorotrast-induced carcinoma of the maxillary sinus which was detected inadvertently in the course of investigation of associated dental pain and labial paresthesia. Clinical and radiobiologic features are presented. It is likely that similar cases remain undetected and at large in the community. PMID- 6928310 TI - Diagnosis and possible causes of vertical root fractures. AB - Thirty-two cases of vertical fractures were studied in an attempt to identify the causes and diagnostic signs normally present. In all of the patients except two, osseous defects were present and could be probed. The majortiy (65.63 percent) had only mild pain or a dull discomfort. Seventy-five percent showed diffuse widening of the periodontal ligament space. This study suggests that excessive force during lateral condensation of the gutta-percha caused 84.38 percent of the fractures. A secondary cause was the forcing or tapping of inlays or dowels into place. The majority (78.13 percent) of the patients were over the age of 40. In all but nine of the cases, treatment consisted of the extraction of the involved teeth. PMID- 6928311 TI - Light microscopy, scanning electron microscopy, and microprobe analysis of bone response to zinc and nonzinc amalgam implants. AB - Freshly mixed, unset zinc-free and zinc-containing analgam was implanted in the right tibia of 32 rats. Half of the specimens were examined by the light microscope and the other half by the scanning electron microscope and x-ray microprobe analysis. It was found that amalgam is well tolerated by the rat osseous tissue, and there were no histologic reaction differences between zinc and zinc free amalgam. The surfaces of the implants were covered by an organic film at 3 weeks and with bone at later intervals. Very little corrosion products containing sulfur were observed on the amalgam surface at all intervals. Bone adjacent to the amalgam contained tin and sulfur irrespective of the presence of zinc in the alloy, indicating outward migration of specific components of the alloy. PMID- 6928312 TI - Nasopharyngeal cephalometrics. AB - A sample of 104 patients, males and females between the ages of 6 and 16 years, was studied. The sample included patients with clinically diagnosed nasopharyngeal obstruction, patients with no obstruction, and random sample of patients for whom the presence or absence of obstruction was not known. More than 200 cephalometric measurements were used in an attempt to identify differences between the first two groups. Statistical t tests revealed four variables, all primarily related to adenoid size and nasopharyngeal dimensions, for which the mean values of the two groups were significantly different. Cephalometric norms for these four measurements were established, using the random sample patients, and these norms were calculated for various ages and both sexes. A method of identifying the degree of obstruction was then formulated on the basis of the four significant measurements. Preliminary results indicate that this method is highly correlated with observed clinical results. PMID- 6928313 TI - Multiple mandibular canals: oddities or fairly common anomalies? AB - It is suggested that multiple mandibular canals are present in a significant portion of our population. It is also suggested that they are often unrecognized, even though they are clearly recorded in panoramic radiographs, and that they are not rare oddities but are fairly common anomalies which are often overlooked when radiographs are being reviewed. PMID- 6928314 TI - Dens invaginatus with ameloblastoma. PMID- 6928315 TI - Lingual mandibular bone cavity. PMID- 6928316 TI - Iatrogenic foreign body. PMID- 6928317 TI - Type I glycogen storage disease with focal nodular hyperplasia of the liver and vasoconstrictive pulmonary hypertension. PMID- 6928318 TI - [The expences of Norwegian households for dental care]. PMID- 6928319 TI - [Acute leukaemia during pregnancy: favourable course of pregnancy in two patients treated with cytosine arabinoside and anthracyclines (author's transl)]. AB - A report of two cases of acute leukaemia discovered during pregnancy. The first was treated from the 24th week with cytosine arabinoside, daunorubicine and vincristine and then rubidazone. Only an incomplete remission was obtained. The pregnancy ended with the birth at the 36th week of a normal child, which remains well at the age of 13 months. The second patient received during the 29th week of pregnancy chemotherapy combining cytosine arabinoside and daunorubicine. Signs of foetal distress appeared at 31 weeks. Delivery took place during the 33rd week in a phase of aplasia. The child was born apparently dead and was resuscitated. A complete remission of the leukaemia was obtained. The child was well at the age of 13 months. A transient neutropaenia was noted at the age of 2 months in both children. PMID- 6928320 TI - [Chronic myeloid leukemia complicating the course of an acute lymphoid leukemia in remission for 7 years]. PMID- 6928321 TI - Determining growth rates of focal lesions of bone from radiographs. AB - Rate of growth divides focal lesions of bone into two classes which are largely mutually exclusive. Not all focal lesions require biopsy, and grading is especially helpful in deciding which should be biopsied and which may be safely followed. The statistical proof and logic of grading as an expression of growth rate are presented with a set of rules establishing each of the five grades in the presence of bone destruction. The radiologic signs necessary to establish rates are described and illustrated. PMID- 6928322 TI - Alcoholism and the medical curriculum. PMID- 6928323 TI - Lithium in depressed chronic alcoholics. PMID- 6928324 TI - Diagnosis and management of the alcoholic patient. PMID- 6928325 TI - Components of change in Rhode Island's physician supply, 1974-1977. PMID- 6928326 TI - Trauma and breast cancer, or the anatomy of an insurance claim. PMID- 6928329 TI - Thin needle aspiration biopsy. PMID- 6928328 TI - The human tumor-bearing limb: an ex vivo model. AB - The present report describes a viable, isolated, perfused, human, tumor-bearing limb model suitable for the study of human host-tumor metabolism. The model is hemodynamically stable with high flow rates (50 cc/kg/min) and low perfusion pressures (mean, 77.2 mm Hg) which are stable over time. Metabolically, the preparation is viable with initial oxygen and glucose uptake 0.88 cc/kg/min and 0.029 mmole/kg/min, respectively. These parameters and lactate concentrations do not change significantly with time. PMID- 6928327 TI - Animal anorexias. AB - Eating very little in the presence of food or failure to serach for food has been documented in various species during the hibernation season, incubation, molting, and defense of the territory or harem. At these times feeding competes with other, more important activities. One way to avoid conflicts between feeding and these other activities to lower the programmed weight or set-point for body fat. Experiments on mammalian hibernators and incubating birds provide evidence that set-points are indeed lowered. Failure to eat in these two examples depends on anorexia, loss of appetite. A review of other examples suggests that conceptualization in terms of lowered set-points provides a unified and testable way of understanding many naturally occurring instances of fasting in the animal kingdom. Finally, spontaneous animal anorexias are contrasted with attempts by people to lose weight. PMID- 6928331 TI - Urinary cytology in endometriosis of the bladder. AB - A case of endometriosis of the urinary bladder in a 27-year-old black female is reported. The cytologic, histologic and clinical findings are presented, and the differential diagnosis is discussed. PMID- 6928330 TI - Differential diagnosis of malignant lymphomas by imprint cytology. AB - The results of a study of 214 touch imprints of benign and malignant lymphoid disorders are presented. The diagnostic criteria, including the results of special stains, are described for both benign proliferative disorders and malignant lymphomas. Imprint cytology achieved an accuracy of 99% in diagnosing both benign and malignant conditions. Specific subtyping of malignant disorders was correctly made in 83% of non-Hodgkin's lymphomas and in 66% of Hodgkin's lymphomas. It is concluded that imprint cytology is a useful adjunct to the histopathologic diagnosis of lymphoid disease. PMID- 6928333 TI - Cytologic diagnosis of intraventricular hemorrhage in a neonate. AB - A neonate with autoimmune thrombocytopenia presented with megacephaly and hydrocephalus. The cause remained obscure until hemosiderin-laden macrophages were found in the ventricular cerebrospinal fluid (CSF), indicating prenatal intracranial hemorrhage. The literature on the diagnosis of intraventricular hemorrhage by the cytologic examination of CSF is reviewed and discussed. The cytologic evaluation of CSF may be helpful in cases of central nervous system dysfunction when the cause is obscure. PMID- 6928334 TI - Diagnosis of Strongyloides stercoralis in sputum cytology. AB - A unique case of hyperinfection with Strongyloides stercoralis in an apparently immunosuppressed host is reported. The organism in various stages of maturation was initially detected by routine sputum cytology. Papanicolaou-stained smears from scrapings of jejunal and colonic mucosa provided specific confirmation of the parasite. Postmortem examination also showed massive tissue and vascular invasion in the intestine with cerebral and pulmonary dissemination. PMID- 6928335 TI - Studies of the distribution of abnormal cells in cytologic preparations. I. Making the smear with a wooden spatula. AB - A model system of 85% exfoliated normal human cervicovaginal squamous cells, 15% exfoliated rodent t-mor cells and acellular, viscous, mucus-like material was used to investigate the distribution of cells on smear preparations. Smears were made by the same individual with wooden spatulas, using traditional smearing motions. The presence or absence of normal squamous cervicovaginal cells and of tumor cells in ten randomly distributed areas was recorded. Smears made with counterclockwise circular motions contained the largest number of tumor cells, and those with zigzag strokes contained the least. Independent of the motion employed, the largest number of tumor cells was found in ring 9 and the lowest in rings 4 and 10. Some of the factors influencing the accumulation of tumor cells in certain areas of the slide may be: unequal pressure of the spatula during smearing, variations in the angle between the instrument and the surface of the slide and the displacement of tumor cells to certain areas of the preparation by overlapping smearing. PMID- 6928336 TI - Estrogen receptor analysis on needle aspirates from human mammary carcinoma. AB - Immediately after mastectomy, estrogen receptor concentration was measured in fine needle aspirates and in histologic tissue specimens from 13 human breast carcinomas. Fine needle aspirates were shown to contain enough material for receptor analysis when the sensitive method of isoelectric focusing in slabs of polyacrylamide gel was used for receptor determination. Aspirations with two different needles (outer diameter 0.7 and 1.4 mm) from each tumor yielded highly correlated receptor values (r = 0.97, p less than 0.0001). There was also a highly significant correlation (r = 0.91, p less than 0.0001) between the receptor content in needle aspirates and in tissue specimens from the same tumor. PMID- 6928332 TI - Vaginal parasitosis. AB - In two cases the ova of parasitic worms, Ascaris lumbricoides and Enterobius vermicularis, were observed in Papanicolaou-stained vaginal smears. The characteristics of each type of ovum are described. PMID- 6928337 TI - Abstracts American Society of Cytology. Scientific session of the 27th annual meeting of the American Society of Cytology, San Francisco, California, October 29-November 3, 1979. PMID- 6928338 TI - The presence of mast cells in eosinophilic pleural effusions. PMID- 6928340 TI - Leukemic iris infiltration. AB - A 7-year-old boy with acute lymphocytic leukemia developed iris infiltration, blood-streaked hypopyon, and high intraocular pressure. A diagnostic anterior chamber paracentesis was performed, which provided a cytologic diagnosis. The aspirate was studied by both the millipore filter technique with Papanicolaou stain and a dried smear using the Wright's stain. Wright's stain provided more distinct cellular details. Irradiation of the anterior segment resulted in clearing of leukemic iris infiltration, hypopyon, and glaucoma. PMID- 6928339 TI - Anorexia and urinary zinc excretion after administration of L-histadine in humans. PMID- 6928341 TI - Orbital fine needle aspiration biopsy with B-scan guidance. AB - In three patients we used B-scan ultrasonography to guide the placement of an aspirating needle, which allowed rapid and accurate cytologic diagnosis of retrobulbar orbital neoplasms. This technique spares the patient the greater costs, inconvenience, and morbidity of more invasive procedures. PMID- 6928342 TI - Beta titanium: a new orthodontic alloy. AB - Historically, few alloys have been used in the fabrication of orthodontic appliances. This article reviews the gold-based, stainless steel, chrome-cobalt nickel, and nitinol alloys, as well as beta titanium, a new material for orthodontics. Mechanical properties and manipulative characteristics are summarized to develop a basis for the selection of the proper alloy for a given clinical situation. The beta titanium wire has a unique balance of low stiffness, high springback, formability, and weldability which indicates its use in a wide range of clinical applications. A number of such applications are described. PMID- 6928344 TI - Dental esthetic self-evaluation and satisfaction. AB - Four hundred eighty-one 10- to 13-year-old children answered questions to determine their skill at self-evaluation and their level of self-satisfaction with their own dental appearance. Their answers were correlated to dental orthodontic variables measured for each child. Findings indicate that while subjects were objective in self-evaluation, there were sex-specific correlates between particular dental variables and self-satisfaction. PMID- 6928343 TI - Centric relation: a comparison of muscle-determined position and operator guidance. AB - Fifteen subjects were used to determine direction and magnitudes of shifts in condylar position when interocclusal records were made by biting hard or easy on a leaf gauge or wax. Electromyographic recordings were made of the temporal and masseter muscles during interocclusal registrations to determine which muscles were most active in seating the condyle when the leaf gauge was used. Results indicated no significant difference in condylar position superoinferiorly between registrations. Biting hard on a leaf gauge caused a significantly more posterior position of the condyle. When this technique is used for obtaining interocclusal registrations, the temporal muscles are more active than the masseters. PMID- 6928345 TI - Changes in the vertical position of the anterior teeth after surgical correction of mandibular protrusion. AB - A group of patients who had undergone an oblique vertical ramus osteotomy for correction of mandibular protrusion was examined 2 years postoperatively in order to clarify whether the treatment resulted in vertical changes of the front teeth. 1. The results indicate an extrusion of both the upper and lower anterior teeth, as the distance from the upper and lower incisors to the NL and ML lines increased postoperatively (0.3 to 2.3 mm.). 2. The clinical crown height increased (0.3 to 0.4 mm.). 3. The root length decreased (0.5 to 0.9 mm.). 4. There were only insignificant changes in the height of the interproximal marginal bone. 5. There was no significant correlation between the changes in crown height and the amount of tooth extrusion; nor was there any correlation between these changes and the changes in mandibular inclination or root length reduction. PMID- 6928347 TI - Philosophizing on educational goals. PMID- 6928348 TI - The inadequacy of cephalometric radiographs for airway assessment. PMID- 6928346 TI - The dentomaxillary complex and overjet correction in Class II, division 1 malocclusion: objectives of skeletal and alveolar remodeling. AB - In recent years it has become apparent that there are limitations to the amount of tooth movement that can be accomplished by alveolar remodeling. Retraction of the maxillary incisor teeth should therefore be avoided during overjet correction if penetration of the palatal alveolar cortex is a probability. Since the Class II, Division 1 phenotype is characterized by abnormalities in both dentoalveolar process and maxillomandibular reactions, trying to compensate for the skeletal discrepancy through alveolar remodeling alone does not have logic on its side. Indeed, treatment philosophies based entirely on a concept of alveolar remodeling cannot be justified on biologic grounds. The most reliable method of avoiding destruction of the palatal alveolar cortex during overjet correction is by means of headgear mechanics designed to produce clinically significant skeletal remodeling. This holds as a general principle, even where extractions are an essential part of the treatment program. Furthermore, because the facial skeleton responds to mechanical deformation more readily in the growing person, the policy adopted by many orthodontists of deferring treatment until the permanent teeth have erupted has little to recommend it. PMID- 6928350 TI - Accurate depth of cut in temporomandibular joint laminagraphs. PMID- 6928349 TI - The amalgamated technique, a mechanically and biologically efficient method for controlled tooth movement. PMID- 6928351 TI - A case report. PMID- 6928355 TI - A pragmatic approach to asepsis in the orthodontic office. AB - It is incumbent upon each orthodontist to conduct his or her practice in a manner that will not cause harm to anyone. By following the procedures described here the orthodontist can minimize and even prevent the possibility of cross infection. This is the best protection against the transmission of hepatitis and other diseases and perhaps the filing of a malpractice suit. PMID- 6928352 TI - Incisor relationships in different skeletofacial patterns. PMID- 6928354 TI - The cervical facebow and mandibular rotation. AB - The purpose of this longitudinal investigation was to determine whether the cervical facebow treatment affected mandibular rotation. Pretreatment and posttreatment tracings were compared using four different methods of superimposition in the headgear group and the control group. Mandibular rotation was measured in parameters of direction and intensity. Statistical evaluations of the data were made to determine significant differences between headgear and control groups. The following conclusions can be made: (1) There is a significant difference among the four methods of cephalometric superimposition. (2) The sella nasion and registration point methods showed a significant difference in mandibular growth direction and intensity between the headgear and the control cases while the intersection and C.C. methods did not. PMID- 6928353 TI - The interrelationships between facial areas and other body dimensions. AB - The data from 35 premenarchial Gujarati, Hindu girls, selected at random, in the age range of 120 months to 144 months were collected to find out statistically the nature and the values of correlation coefficients among various facial areas and other body dimensions such as body weight, stature, chronological and skeletal ages. The correlation coefficients between skeletal, chronological, height and weight ages ranged from 0.413 to 0.8105 showing moderately high association. Height and weight ages turned out to be the most reliable indicators of growth and development of facial areas in this age group and the chronological age as in ineffectual indicator of the same. Maxillary and mandibular areas showed a high value of correlation coefficients (0.67) while the orbitoethmoidal area did not show any correlation with any age variables or with other facial areas. The mandibular areas showed the highest correlation with weight age (0.63) and lowest with chronological age (0.431). The maxillary area showed highest correlation with chronological age (0.62) and lowest with skeletal age (0.42). Fifteen empirical formulae have been developed by which average value of facial areas could be predicted from the other variables. PMID- 6928356 TI - Physical properties of ZnO base and resin cements. AB - Some physical properties of zinc phosphate, zinc polycarboxylate, and a resin cement of thick consistency suitable for cementation of orthodontic bands were evaluated. A new technique for evaluating the setting time is described. The setting times for resin and zinc polycarboxylate cements were about the same but less than that for zinc phosphate. The properties of percent solubility and compressive strength were significantly superior for resin cement. PMID- 6928357 TI - Comments on a method to predict and prevent mandibular incisor relapse. PMID- 6928358 TI - Caveat lector: the necessity of reading critically. PMID- 6928359 TI - Acute lymphoblastic leukemia: hand mirror variant. AB - The presence of numerous hand mirror cells in the bone marrow of patients with acute leukemia may be related to a good prognosis. To further evaluate this relationship, the bone marrows of 21 consecutive patients with a diagnosis of acute lymphoblastic leukemia were reviewed for the presence of greater than 40% hand mirror cells. Four of these 21 patients (19%) demonstrated this finding during the course of their illness. These patients were characterized by ease of remission and/or prolonged survival. Three (75%) patients are alive and well at the time of this writing. At the present time, of the 17 patients without hand mirror cells, seven (41%) are alive and ten (59%) are dead. Although not statistically significant, our findings suggest a positive relationship between the presence of greater than 40% hand mirror cells in the bone marrow ans a favorable prognosis. Future larger prospective studies are indicated to further understand the importance of this complex, apparently immunologically stimulated cell. PMID- 6928362 TI - Dental services for children in England and Wales. PMID- 6928360 TI - Tissue lipids in hyperammonemic encephalopathies of childhood. AB - Cholesterol, triglyceride, free fatty acid, and phospholipid concentrations were measured in 33 brain, liver, and adipose tissue samples obtained from 17 children who died of an acute encephalopathy associated with liver dysfunction and hyperammonemia (hyperammonemic encephalopathy). Eleven patients had Reye's syndrome, three had acute "toxic" encephalopathy (without fatty liver), two had glycogen storage disease type 1, and one had congenital hyperammonemia type 2. Hepatic triglyceride concentrations were markedly increased in Reye's syndrome, but varied from normal to increased concentrations in other hyperammonemic encephalopathies. In contrast, the acute encephalopathy could not be differentiated on the basis of clinical, laboratory, or pathologic features and the brain lipid profiles were remarkably similar among all patients studied. PMID- 6928364 TI - Domiciliary visit. PMID- 6928363 TI - British Orthodontic Standards. Working Party report. PMID- 6928365 TI - The emergence of a speciality. PMID- 6928366 TI - Is the six-monthly dental examination generally necessary? PMID- 6928361 TI - The use of tooth fragments in species determination. PMID- 6928368 TI - A wider persepctive. PMID- 6928367 TI - Orthodontics for the adult patient. Part 1.--Introduction. PMID- 6928369 TI - Toothpaste ingestion during toothbrushing by school children. PMID- 6928370 TI - To lease or not to lease. Part I--Motor cars. PMID- 6928371 TI - Salvation by odontalgia. PMID- 6928372 TI - Dental disease in brunus edwardii. PMID- 6928373 TI - To lease or not to lease. Part 2.--Dental equipment. PMID- 6928374 TI - 3-Mercaptopyruvate sulfurtransferase: rapid equilibrium-ordered mechanism with cyanide as the acceptor substrate. AB - A steady-state kinetic analysis of 3-mercaptopyruvate sulfurtransferase (EC 2.8.1.2) using cyanide as the sulfur-acceptor substrate was performed. Measurement of pyruvate production gave initial velocity patterns and secondary plots characteristic of a rapid equilibrium-ordered sequential mechanism. Initial velocity data obtained by measuring the formation of thiocyanate, which is the other reaction product, revealed a discrepancy between the rates of pyruvate and thiocyanate production; the yield of thiocyanate per unit time was smaller than that of pyruvate for each reaction mixture. This velocity discrepancy, which diminished with approach to cyanide saturation, suggests that sulfur is not discharged from the enzyme as thiocyanate, but as elemental sulfur, and that thiocyanate is formed in a subsequent nonenzymic step. A formal mechanism which has a rapid equilibrium-ordered catalytic cycle and elemental sulfur as one of the initial reaction products is proposed. Computer simulation is used to show that this model is in agreement with all of the kinetic data. PMID- 6928375 TI - Bifunctional enzyme activity at the same active site: study of 3 alpha and 20 beta activity by affinity alkylation of 3 alpha, 20 beta-hydroxysteroid dehydrogenase with 17-(bromoacetoxy)steroids. PMID- 6928376 TI - Partial purification of a human liver sulphotransferase active towards bile salts. AB - An enzyme that catalyzes the transfer of sulphate from 3'-phosphoadenosine 5' phosphosulphate to bile salts was purified from human liver cytosol by chromatography on DEAE-Sephadex and Sephadex G-200, by agarose suspension electrophoresis and by isoelectric focusing in free solution. The purified enzyme was also active towards oestrone, dehydroepiandrosterone and phenol. No other liver steroid sulphotransferases could be detected during this purification procedure. Km values of 1.8 . 10(-6) M and 3.3 . 10(-6) M for glycolithocholate and 3'-phosphoadenosine 5'-phosphosulphate respectively were found. The sulphotransferase has an isoelectric point of 5.5. The enzyme was markedly activated by Mg2+, Mn2+ and Co2+ and inhibited by Cu2+, Fe2+ and Zn2+. Chenodeoxycholate and deoxycholate were sulphated at the 7-OH and 12-OH position, respectively. No bile salt disulphate formation was detected. A 30-fold increase in specific activity was obtained, although the purification based on ultraviolet light measurements was considerably higher. PMID- 6928377 TI - Premature chromosome condensation studies in human leukemia. 2. Proliferative potential changes after induction therapy for AML patients. PMID- 6928378 TI - Pretreatment flow cytometry of DNA content in adult acute leukemia. PMID- 6928379 TI - Dysmyelopoietic syndrome: sequential clinical and cytogenetic studies. AB - Clinical and cytogenetic studies were done on 8 patients with dysmyelopoietic syndrome: 6 of these patients had refractory anemia with an excess of blasts (RAEB), and 2 patients had chronic myelomonocytic leukemia (CMML) according to the French-American-British classification. The ages of these 8 patients (3 female and 5 male) ranged from 45 to 70 yr (median, 61.5 yr). Seven of the 8 patients died 3-86 mo (median, 11 mo) after the onset of symptoms of hemorrhage or infections. Cytogenetic studies of bone marrow cells with the Q-banding technique showed clonal karyotypic abnormalities in 7 of the 8 patients (87.5%). Five of the 7 chromosomally abnormal patients had very complex karyotypes; all 7 patients, however, had at least 1 of 4 specific changes: -5 (or 5Q-), -7, +8, and +21. Three of the 7 patients with abnormal karyotypes had had some exposure to potential mutagenic/carcinogenic agents. Five of the 7 patients had serial cytogenetic analyses, 4 of which showed evolution of the karyotype to further complexity; in 2 cases, this coincided with the evolution of the disease into acute leukemia. The median survival time of patients whose initial cytogenetic samples showed both normal and abnormal metaphases was more than twice that of patients who had only abnormal metaphases initially (12 mo versus 4.5 mo). PMID- 6928380 TI - Health politics, cost containment, and government efficiency. PMID- 6928381 TI - Politics of cost control abroad. PMID- 6928382 TI - Promising approaches to cost containment: a conceptual framework. PMID- 6928383 TI - Promising approaches to cost containment: the health insurance view. PMID- 6928384 TI - Promising approaches to cost containment: an industry view. PMID- 6928385 TI - Promising approaches to cost containment: a view from the medical profession. PMID- 6928387 TI - The PSRO role in cost containment. PMID- 6928386 TI - The antitrust laws, the Federal Trade Commission, and cost containment. PMID- 6928388 TI - The view from the Health Systems Agency. PMID- 6928389 TI - A view from the municipal hospital. PMID- 6928390 TI - Health care politics and cost containment. PMID- 6928393 TI - The impact of cost containment on the health system and the patient: the New York State experience. PMID- 6928392 TI - The impact of cost containment on the health system and the patient: the view from Blue Cross. PMID- 6928391 TI - The Administration's program for health cost containment. PMID- 6928394 TI - Mechanical aids to ventilation for use in the field. PMID- 6928395 TI - Choosing the baby's sex. PMID- 6928396 TI - Induced acute non-lymphocytic leukemia following long-term chemotherapy: a study of 20 cases. AB - Twenty individuals developed acute non-lymphocytic leukemia (ANLL) following long term chemotherapy for other disorders. The primary disorders included non Hodgkin's lymphoma (five), Hodgkin's disease (five), carcinoma (four), multiple myeloma (three), chronic leukemia (two), and rheumatoid arthritis. Leukemia developed from 11-132 months (mean approximately 60 months) following institution of chemotherapy and all cases have occurred since 1974. Pre-leukemic cytopenias were present in 15 individuals. Fifteen of the 20 patients had chromosome analyses and 14 were abnormal. The leukemia was invariably refractory to chemotherapy with a median survival of only two months. Of the patients autopsied, only one individual had any evidence of the primary malignancy. This study illustrates the need for surveillance for secondary ANLL following long term chemotherapy with/without radiotherapy. Duration of optimal chemotherapy for the primary disease must be determined by control trials and weighed against the risk of developing a secondary leukemia. PMID- 6928397 TI - Evaluation of drug-antibody conjugates in the treatment of human myelosarcomas transplanted in nude mice. AB - Methotrexate, daunomycin, and chlorambucil were independently conjugated to immune goat gamma-globulins specifically raised to the Ph1 + chronic myelogenous leukemia cell line K-562. The drug-antibody conjugates were then tested against myelosarcomas made up of K-562 cells growing in nude mice and their efficacy was compared with that of the drug alone, gamma-globulins, a mixture of the two, or conjugates of drugs with normal goat gamma-globulin. Conjugation methods for methotrexate and daunomycin abrogate the antibody activity as indicated by the absence of complement-mediated cytotoxicity of the conjugates in vitro and the lack of effect on myelosarcomas in vivo. Simultaneous administration of either of these drugs and antibody partially abrogated the development of myelosarcomas. Chlorambucil-antibody conjugates, however, retained their cytotoxicity in vitro and were found effective in vivo. It is the first successful attempt to covalently bind chlorambucil to gamma-globulins without the loss of drug or antibody biological activity. Although the simultaneous administration of chlorambucil and gamma-globulins and conjugated drug gamma-globulins reduced the growth of myelosarcomas considerably, the immune gamma-globulins alone either reduced their weight to a larger degree or eliminated their growth completely. Results of this study indicate that myelosarcomas made up of K-562 cells grown in nude mice are good and reproducible models for testing various therapeutic agents. The advantage of using human cells proliferating in an in vivo environment brings experimental therapy one step closer to clinical trials. PMID- 6928399 TI - Sister chromatid exchange and growth kinetics of marrow cells in aneuploid acute nonlymphocytic leukemias. AB - On the basis of a bromodeoxyuridine chromosome-labeling method, we have studied the sister chromatid exchange (SCE) incidence and growth pattern in cultured leukemic marrow cells from 12 acute nonlymphocytic leukemia patients, 10 with acute myeloblastic leukemia. 1 with acute erythroleukemia, and 1 with acute promyelocytic leukemia with various karyotypic abnormalities. The leukemia cells in these patients were readily identified on the basis of the chromosome anomalies. There was no clear karyotypic relevance to the SCE incidence and growth pattern among the aneuploid leukemic cells. In most of the cases examined, however, the aneuploid leukemic cells were characterized by a low SCE incidence and considerably prolonged cell cycle time, as compared with those in the normal diploid cells which appeared during remission or coexisted with the leukemic cells at the early stages or during relapse of the disease. In most cases, this situation did not change in the aneuploid leukemic cells even after chemotherpeutic treatment, while the normal diploid cells exhibited an increased SCE frequency and, in some cases, alteration of growth pattern after chemotherapy. Possible differences in the susceptibility to the chemotherapy of the leukemic and normal cells in relation to the different growth capacity of these cells are discussed. PMID- 6928400 TI - Near haploid cell line in lymphoid blast crisis of Ph1-positive chronic myeloid leukemia. AB - This report describes a case of lymphoid blast crisis of a chronic myelocytic leukemia with the occurrence of a double chromosomal population carrying a Philadelphia chromosome. Fifty-five % of the cells have 28 chromosomes, and 36% show the exact duplicate of the near haploid chromosome complement. The similarities between this near haploid cell line and those previously reported, as well as the presence of such clones in acute lymphoblastic leukemia, are discussed. In the leukemic lymphoblasts, the association of the Philadelphia chromosomes with a near haploid karyotype described so far in acute lymphoblastic leukemia provides further support for the concept of a pluripotent Philadelphia chromosome-positive stem cell common to both lymphoid and myeloid lines. PMID- 6928398 TI - Growth suppression of human leukemic cells in vitro by L-ascorbic acid. AB - The suppressive effect of L-ascorbic acid on the growth of bone marrow cells from patients with acute nonlymphocytic leukemia was studied using a modified agar culture method featuring daily feeding to allow the growth of leukemic cell colonies. In seven of 28 patients (25%), the numbers of leukemic cell colonies grown in culture were reduced to 21% of control by the addition of L-ascorbic acid (0.3 mM) to the culture medium. Glutathione did not suppress leukemic cell colonies although it has a similar oxidation-reduction potential to that of L ascorbic acid. The addition of L-ascorbic acid reduced the pH of the medium. However, a comparable reduction of pH by the addition of HCl did not suppress leukemic cell colonies. In simultaneous cultures for leukemic and normal marrow cells, the suppression of leukemic cell colony was noted with a concentration of L-ascorbic acid as low as 0.1 mM (a concentration achievable in vivo), but normal myeloid colonies were not suppressed until the concentration of L-ascorbic acid reached an extremely high level (1 mM). In conclusion, growth of leukemic cells in culture was suppressed by L-ascorbic acid in a substantial proportion of patients with acute nonlymphocytic leukemia. This suppression was a specific effect of L-ascorbic acid and was not due to its oxidation-reduction potential or pH change. Leukemic cells were selectively affected at an L-ascorbic acid concentration attainable in vivo while normal hemopoietic cells were not suppressed. PMID- 6928401 TI - A relationship between estrogen sulfurylation and estrogen and progesterone receptor status in human mammary carcinoma. AB - It was previously demonstrated that a correlation existed between estrogen receptor (ER) status and levels of estrogen sulfotransferase in human mammary cancer, high levels being associated with ER-positive and low levels with ER negative tumors. We have now examined these same parameters, along with progesterone receptor (PGR) status, in 44 primary human mammary tumors. Tumors which were both ER-positive and PGR-positive (n = 21), showed significantly higher levels of estrogen sulfotransferase compared to ER-positive PGR-negative (n = 12) and ER-negative PGR-negative (n = 11) tumors. These values (pmol estradiol sulfate per mg protein per 2 hr) were 72 +/- 12 (S.E.), 25 +/- 5, and 11 +/- 4 (p less than 0.01 and less than 0.005, respectively). There was no significant difference between ER-positive PGR-negative and ER-negative PGR negative tumors. The possible involvement of PGR in the regulation of estrogen sulfotransferase is discussed. PMID- 6928402 TI - Levels of cytotoxic reactivity to cultured normal skin fibroblasts in sera from normal and sarcoma-bearing patients. AB - Human sera possess complement-dependent cytotoxic reactivity against autologous and allogeneic cultured normal skin fibroblasts. Previous studies indicated that the natural antibody reactivity is directed against fetal antigens expressed on these cells in tissue culture. The reactivity was further characterized in the present study. Chromatographic analysis of a normal serum indicated that its reactivity belonged to the immunoglobulin M (19S) class of immunoglobulins. Sera from 22 preoperative tumor-bearing osteogenic sarcoma patients, 30 tumor-bearing soft-tissue sarcoma patients, and 52 age- and sex-matched normal individuals were tested against allogeneic skin fibroblasts. The patient and normal groups displayed wide, overlapping ranges of cytotoxicity. The osteogenic sarcoma group showed a small but significant increase in mean cytotoxicity compared to the controls, whereas the soft-tissue sarcoma sera were not significantly different from the controls. Reactivities in the sera of patients whose tumors recurred were not significantly different from those of the patients who remained disease free. Cytotoxic levels in sera from eight osteogenic sarcoma patients followed throughout the clinical course remained constant up to the time of documented recurrence and were not affected by surgical removal of the primary tumor or Bacillus Calmette-Guerin immunotherapy. In three of four patients whose tumors recurred, cytotoxic levels fell, but only after documented recurrence. The natural antibody reactivity against normal fibroblasts does not appear useful as a marker for diagnosis, prognosis, or monitoring tumor presence in sarcoma patients. PMID- 6928403 TI - [Hypotonic syndrome due to unusual causes]. PMID- 6928405 TI - Prazosin in acute anthracyclene cardiomyopathy. AB - A 32-year-old woman with a 14-month history of acute lymphoblastic leukemia received 300 mg/sq m of doxorubicin. Shortly after the last course of therapy, congestive failure developed that was attributed to anthracyclene cardiomyopathy. Three weeks later, an acute septic episode was complicated by hypotension and low cardiac output. Adequate blood pressure and cardiac output were restored with a combined intravenous infusion of dopamine hydrochloride and nitroglycerine. Within 24 hours, oral therapy with prazosin and digitalis was initiated, and two days later, the intravenous infusions could be discontinued. Acute anthracyclene cardiomyopathy can be successfully treated with a combination of oral inotropic and vasodilating agents. PMID- 6928404 TI - Surfactant inhibition of cholesterol oxidase. AB - Little is known of the effect of surfactants upon the activity of cholesterol oxidase. This study demonstrates the interrelationship of surfactant, enzyme and substrate, and illustrates a possible source of inaccuracy within an enzymatic cholesterol assay. Using the rate at which cholesterol is converted to delta 4 cholestenone, the reaction was followed directly bby monitoring the increase in absorbance at 240 nm. Inhibition of cholesterol oxidase was demonstrated with three surfactants, hydroxypolyethoxydodecane, Tween 20 and Triton-X-405. A fourth, Triton-X-100, produced high enzyme activity, although low concentrations resulted in incomplete substrate dispersal and high concentrations caused high blank values. Hydroxypolyethoxyduodecane was studied more closely and the mechanism of inhibition is suggested as poor substrate dispersal at low surfactant concentration and a competitive inhibition at higher concentrations. PMID- 6928406 TI - Short-term effect of ammonium chloride on nitrogen fixation by Azotobacter vinelandii and by bacteroids of Rhizobium leguminosarum. PMID- 6928407 TI - Tritiated thymidine triphosphate nuclear labelling in 48 patients with acute leukaemia. (Correlation with clinical data and response to chemotherapy). PMID- 6928408 TI - Dehydrogenases requiring nicotinamide coenzymes. PMID- 6928409 TI - Periodontal considerations. AB - An attempt has been made to outline the basic periodontal approach to patients who require removable partial dentures. The education, examination, motivation, and treatment of periodontal disease prior to undertaking restorative procedures has been presented from a pragmatic approach. The underlying rationale is based on patient awareness without which the total dental health programs is in jeopardy. PMID- 6928410 TI - Accreditation problems: ADA joins corporate membership. PMID- 6928412 TI - Satellite associations and silver staining in a case of multiple G and D variants. AB - Satellite associations and silver staining were analyzed in a normal woman carrying three "s" variants, on chromosomes 13, 21, and 22. Six of the acrocentric chromosomes were identified and a positive correlation between the parameters of satellite association frequency and positive silver staining was found for each chromosome. These parameters seem to depend on the presence and size of a secondary constriction and are unaffected by stallelite size. PMID- 6928413 TI - Expression in fibroblast culture of the satellited-X chromosome associated with familial sex-linked mental retardation. AB - The satellited-X chromosome previously shown in lymphocyte culture to be associated with certain types of sex-linked mental retardation has, for the first time, been demonstrated in cultured skin fibroblasts and lymphocytes from two affected males and an obligate carrier female. These findings provide a basis for reliable diagnosis of female carriers and for the development of prenatal diagnosis. PMID- 6928411 TI - Assignment of a structural gene for a fourth human diaphorase (DIA4) to chromosome 16 in man-mouse somatic cell hybrids. AB - A diaphorase (DIA4), different from similar enzymes so far described in man, has been detected electrophoretically in human tissues and fibroblasts. The enzyme which is active both with NADH and NADPH was missing in erythrocytes. It was consistently undetectable in part of the diploid fibroblast cultures analyzed. The activity could be separated by Cellogel electrophoresis from rodent diaphorases. In manmouse somatic cell hybrids human DIA4 segregated with chromosome 16. This result indicates that its structural gene is located on this autosome. The enzyme exhibits similarities with a NAD(P)H dehydrogenase (EC 1.6.99.2) described in rat liver. PMID- 6928415 TI - Geographic patterns of leukemia in the United States. PMID- 6928414 TI - Epiphyseal extension of metaphyseal osteosarcoma in skeletally immature individuals. AB - In a restrospective macroscopic and microscopic study of twenty-six macrosections of skeletally immature individuals with metaphyseal osteosarcoma, we determined the incidence, extent, and mode of tumor extension into the epiphysis. The physis appeared to have a tendency to act as a barrier to tumor spread, but did not restrain the tumor tissue in most cases. Epiphyseal extension of the tumor tissue was massive in more than half of the cases, with tumor tissue abutting against the articular cartilage, and in one instance perforating it. Some tumors had a sizable extra-osseous component that extended around the physis beneath the perichondral ring and capsular structures into the ossific nucleus. These findings have important implications when limited surgery is performed for appendicular osteosarcoma. PMID- 6928416 TI - Nonrespiratory functions of the human lung: in vitro metabolism of tritium labeled progesterone and pregnenolone. PMID- 6928417 TI - Influence of alkaline pH on the effectiveness of sodium fluoride dentifrices. AB - Two similar sodium fluoride dentifrices, one neutral and one alkaline, were compared to a placebo for clinical effectiveness in reducing caries. The neutral dentifrice contained 35% less soluble fluoride than the alkaline dentifrice. Both fluoride dentifrices were significantly effective but were not different from each other. PMID- 6928418 TI - Simultaneous analysis of respiratory gases and nitrous oxide in dental patients. AB - The simultaneous analysis of respiratory gases in the presence of nitrous oxide is described. The modified gas chromatographic technique used is especially applicable to dental situations where continuous monitoring is not necessary. It employs readily available equipment and does not involve interference with other dental procedures. PMID- 6928419 TI - Jaw muscle silent periods: the effect of acrylic splints. AB - Jaw muscle silent periods were recorded in response to a chin tap during maximal clench in asymptomatic subjects. The insertion of a palatal splint did not change the silent period duration. However, an occlusal splint, or part of it, caused a significant increase in the duration of the silent period. PMID- 6928420 TI - Corrosion behavior of Au and Ag modified Cu-Ni-Mn alloys. AB - The linear electrochemical polarization method was used to provide quantitative in vitro measurements of corrosion rates as a function of exposure time for Cu-Ni Mn, Cu-Ni-Mn-Au, Cu-Ni-Mn-Ag, and Cu-Ni-Mn-Au-Ag alloys in artificial saliva. Both Au and Ag additives to dental-cast Cu-Ni-Mn alloys lowered the corrosion rate significantly. PMID- 6928421 TI - An abrasion test for composite resins. AB - An abrasive wear test for composite resins was proposed. A slurry of glass pearls and abrasive particles were used. The abrasive effect was examined for different particle sizes. Particle sizes were found which gave the same order of wear as found clinically for an amalgam, a composite resin, and unfilled resin. PMID- 6928423 TI - Fluctuating asymmetry in the deciduous dentition. PMID- 6928422 TI - A long-term evaluation of abrasion of dental composite resins. AB - A long-term study was performed on the abrasion of dental composites stored in different solutions for six months. No difference in wear resistancewas noticeable between the water and lactic acid group. But the composite with regular filler showed reduced wear resistance when compared with a microfiller composite. PMID- 6928426 TI - Grade averages and DAT scores poor performance predictors. PMID- 6928424 TI - The effect of electrode placement and instrumentation of the masseteric silent period. PMID- 6928425 TI - Molar size sequence in the great apes: gorilla, orangutan, and chimpanzee. AB - In ape dentitions the common molar size sequence is assumed to be MC greater than M2 greater than M1. This sequence is held in contrast to the assumed human sequence, M1 greater than M2 greater than M3. Using mesiodistal, buccolingual, and cross-sectional area dimensions, this study indicates that the molar size progression in all three great ape species varies extensively from the assumed sequence. PMID- 6928427 TI - Hazy difference between theory and utility. PMID- 6928428 TI - Increasing recruitment and retention of minority students in health programs- dentistry. PMID- 6928429 TI - Recruitment of ethnic and socio-economically disadvantaged students into dentistry. AB - A program designed to attract and graduate underrepresented minorities and disadvantaged students in dentistry is reported. The program consisted of three phases: career orientation, recruitment, and academic enrichment/retention. In the six years of this program's existence, the number of minority students enrolled increased from 1 to 28, including 12 who were graduated by June 1979. Only two were lost because of academic difficulties. An analysis of grades and tutorial needs showed that students experienced the most difficulty with first year basic science courses. Recommendations are presented for program improvement. PMID- 6928430 TI - Deferred compensation as a method for payment of part-time dental faculty members. AB - Education costs are causing part-time dental educators to be compensated at inappropriately low levels. By using a deferred compensation plan, the dental school can provide to the part-time educator, a greater return at a time when that money will be of more benefit. Through contractual agreement with the dental school, as drawn up by appropriate financial and legal counsel, a plan can be constructed that can significantly increase the real value of part-time earnings, usually payable at some time in the future, at no additional cost to either the dental school or the part-time dental educator. PMID- 6928431 TI - Interpersonal support and coping among first-year dental students. AB - Previous studies have suggested that individuals involved in supportive interpersonal relationships are buffered against the deleterious effects of stress. This hypothesis was evaluated in a dental school setting by examining the support networks of 63 first-year students. Levels of support were correlated with academic performance and indices of physical and psychological well-being. For men, social support was generally associated with better performance and well being. Women, on the other hand, exhibited predominately negative relationships between support and all outcome measures. An unexpected finding for both men and women was the consistent, positive relationship between support and reported drug use. Tentative interpretations of the drug use findings as well as the paradoxical support-performance correlations for women are made. Several strategies for enhancing support system benefits are suggested. PMID- 6928432 TI - Introducing the college student to dental research. PMID- 6928433 TI - A survey of career assistance programs at U.S. dental schools. AB - 1. There is a perceived need among the leaders of our dental schools for career assistance programs for dental students. 2. Current programs and services for transmitting career assistance at a majority of dental educational institutions are either nonexistent or sporadic, and handled informally without carefully coordinated activities. 3. The most frequently used career assistance services, where programs do exist, are a library of career informational materials, formalized arrangements with outside professionals in the community, and placement services. 4. Among the variety of individuals coordinating current programs in career assistance in dental schools, the most common is a member of the administration (primarily the director of student affairs). PMID- 6928434 TI - Lidocaine metabolism and toxicity: a laboratory experiment for dental students. AB - A laboratory exercise for dental students based on a modification of the classical pentobarbital sleeping-time experiment is presented. The substitution of a toxic dose of lidocaine in place of an anesthetic dose of pentobarbital allows demonstration of the same general principles of drug metabolism, i.e., induction of the hepatic drug metabolizing systems by phenobarbital, reduction of hepatic drug metabolism by liver damage or disease, or both, and the relationship between the rate of drug detoxification and the duration and intensity of drug effects. However, the use of lidocaine demonstrates its toxic and lethal actions and increases the relevance of the experience for dental students. PMID- 6928435 TI - Evaluation of one-to-one behavioral training. PMID- 6928437 TI - American Association of Dental Schools' Faculty Salary Survey 1979-80. PMID- 6928436 TI - American Association of Dental Schools curricular guidelines for orthodontics. PMID- 6928438 TI - Thrombocytopenia as a leukemic prodrome. PMID- 6928439 TI - An apparatus for the preparation of cavities in the canine teeth of ferrets. AB - An apparatus is described for the preparation of standardized cavities in the canine teeth of ferrets. One hundred cavities were cut, and there was highly significant correlation between the distance the bur was advanced (machine depth) and the cavity depth in dentine. It was possible to cut cavities predictively with small and large residual dentine thicknesses. The method described was not damaging to the pulp. PMID- 6928440 TI - The in vitro effect of a glass ionomer cement on dentine and enamel walls. An electron probe and microradiographic study. AB - Glass ionomer cement (ASPA) was inserted in unconditioned class V cavities or in contact with polished ground surfaces of enamel and dentine in twelve teeth. Ground sections of all teeth were examined by microradiography, and four of the sections submitted to electron probe microanalysis. A narrow outer zone of increased radiopacity in the dentine walls was explained by a 5--10% increase of Ca and P. In some sections this zone covered a partly demineralized subsurface zone. The concentrations of F and Al in enamel and dentine were similar to or approximately 0.3% and 1.5%, respectively, decreasing to less than 0.1% at a distance of 16--80 microns (F) and 8--24 microns (A) from the surface. Both F and Al penetrated deeper into the dentine than into the enamel. Decreased Zn values, sometimes concomitant with increased Ca, P and Mg values, were in some instances observed in an outer narrow zone of the dentine walls. It is assumed that like silicate cement, glass ionomer cement must have anticariogenic properties, due to uptake of F and Al in cavity walls. PMID- 6928441 TI - An in vitro model for studying adsorption of oral streptococci to crown and bridge cements. AB - A sensitive, in vitro method has been developed for the study of bacterial adsorption to dental crown and bridge cements. The method employs heavily radiolabelled cells which adhere to the wall in wells made from the cements. Loss of radioactivity from the bacterial suspension during incubation is used to measure the degree of bacterial adherence to the materials. Strains of Streptococcus sanguis and Streptococcus mutans adhered in greater numbers than a strain of Streptococcus salivarius to both a zinc phosphate cement and a zinc carboxylate cement. The zinc phosphate cement supported adherence to a greater degree than did the zinc carboxylate cement. Pretreatment of the cement surfaces with human saliva tended to reduce bacterial adherence. Pretreatment of the bacteria with saliva slightly enhanced sorption of S. sanguis and S. salivarius, but tended to impair sorption of S. mutans to both types of cements. When both bacteria and cements had been pretreated with saliva, a strong inhibition of the adherence of S. mutans was observed. PMID- 6928442 TI - The temporomandibular joint in children after breech delivery. AB - In an effort to explain the aetiology of early temporomandibular joint (TMJ) injuries, their incidence in children born by vaginal breech delivery and possible correlation with such deliveries were investigated. The study covered 156 children aged from 4 to 6 years, eighty-three of them born by vaginal breech delivery under application of the classical Mauriceau manoeuvre in seventeen cases and the Bracht manoeuvre in sixty-six. Seventy-three children delivered spontaneously in vertex presentation served as the control group. Signs of TMJ injury were found in 59.6% of the total group, the by-birth percentages being 67.5 in those after breech delivery and 50.7 in those after spontaneous delivery- the difference is statistically significant. The difference was even more significant for the more severe TMJ disorders, their percentages being in two groups respectively 48.2 and 29.7. In the children born by breech delivery the TMJ disorders were invariably attended by severe forms of distocclusion, among which the unilateral form deserves particular attention. The authors conclude that vaginal breech delivery is probably among the factors responsible for early TMJ abnormalities. They call the attention of paediatricians and obstetricians to this fact and urge examination of this joint as a very important part of oral examination in children born by vaginal breech delivery. PMID- 6928443 TI - Fluoride concentrations in fissure and cervical enamel of unerupted human teeth. AB - Fluoride concentration of fissure enamel from unerupted third molars was higher than that of the cervical-lingual but not cervical-buccal surfaces at a similar depth of the removed enamel. The highest fluoride concentration was found in the fissure enamel due probably to its earlier formation, higher permeability and embedding tissue before eruption. PMID- 6928444 TI - The use of differential scanning calorimetry for the evaluation of dental materials. I. Cements, cavity lining materials and anterior restorative materials. AB - Thermal changes occurring during the setting of restorative materials have been measured accurately using a differential scanning calorimeter. The results were used to evaluate setting characteristics. The heat of reaction and rate of heat output may be significant in determining thermal damage to the pulp. The heat capacity is related to thermal insulation properties. These properties have been determined and their effect on the efficacy of restorative materials discussed. PMID- 6928445 TI - Destruction of the soft palate and nose by tertiary 'benign' syphilis. A case report. AB - A case of untreated tertiary syphilis involving the soft palate and nose is described and the treatment is outlined. In view of the rising incidence of acquired syphilis the clinician should bear this disease in mind whenever atypical lesions are encountered. PMID- 6928446 TI - Masticatory efficiency. AB - A method for measuring masticatory efficiency is described as well as a mathematical formula expressing the masticatory efficiency as an index. A silicone compound was used as test material. The masticatory efficiency index was calculated as the mean of the best four out of five consecutive measurements of masticatory efficiency calculated from a specially designed formula. PMID- 6928448 TI - Some electromyographic parameters of experimental tooth clenching in adult human subjects. AB - Eight adult human subjects exercised maximal voluntary tooth clenching until fatigue and pains were experienced, and could no longer be endured, in the right masseter muscle. The integrated electrical activity in the right masseter muscle was determined as a ratio of the different isometric exercises, and it showed a consistent decrease from onset of fatigue, via onset of pains, to the endurance of pains, possibly because of progressive muscle fatigue. The relative muscle activity might have determined the perception of the moment of onset of fatigue in the masseter muscle, and the perception of the moment of muscle exhaustion, but not the perception of the moment of onset of muscle pains. PMID- 6928449 TI - The strength and fracture toughness of calcium hydroxide preparations. AB - The strength of a brittle material depends upon the toughness of the material itself and the degree of perfection with which it can be placed. This study shows that both the compressive and tensile strength of calcium hydroxide lining materials is dependent on the fracture toughness at unstable crack propagation, KIC, and the size, number and distribution of pores (which are the defects that nucleate fracture). Of the products tested here, Dycal possesses the greatest actual strength due to a higher than average KIC value and relatively few isolated small pores. However, the greatest potential for strength exists in Reocap which has a KIC value a factor of 2.4 greater than its nearest rival (Dycal). Unfortunately its strength, as determinedhere, is less than Dycal due to the large number of pores in close proximity to each other. PMID- 6928447 TI - Ionic transport through bis-glycidyl methacrylate films. AB - Specific ion meter studies have shown that ionic transport through bis-GMA fissure sealant films is selective and that dissolved fluoride ions disappear from the solution around tooth sections at a more rapid rate than do calcium and chloride ions. This would indicate that topical fluoridation of pits and fissures can still be effected after placement of a fissure sealant. A causative mechanism for this phenomenon has been postulated. Calcium exchange studies indicate that calcium is removed from the enamel and that the microsolubility of fissure sealed teeth in CaCl2 solution is increased by the preparative and sealing procedure used for the enamel. PMID- 6928450 TI - Fluoride uptake by cavity walls following application of Duraphat around amalgam restorations. AB - This study aimed to assess possible fluoride uptake by cavity walls following a single application of Duraphat around class V or I amalgam restorations which were inserted in seventeen human premolars in vitro and in vivo. Six cavities were lined with one layer of Copalite before insertion of the restorations. After a week in vivo and 12--24 h in vitro, 200--300 micrometers thick longitudinal sections passing through the cavities were prepared. By electron probe microanalysis F concentrations ranging from 2000 to 6000 ppm were measured near the surface of the cavity walls. Copalite seemed to inhibit F uptake. The study indicates that F ions released from the Duraphat varnish have been taken up by the cavity walls. Such uptake may influence development of secondary caries (wall lesions) in connection with amalgam restorations. PMID- 6928451 TI - The structure of experimental in vitro lesions around glass ionomer cement restorations in human teeth. AB - Class V cavities were prepared at the amelo-cementum junction in sixty-eight extracted human teeth. Fifty-one were filled with glass ionomer cement (ASPA). 'Secondary carious' lesions were produced around thirty-five of the restorations by exposure to acidified gelatin. Thirty-three teeth served as controls of the effect of the preparation procedure, the conditioner, the ASPA liquid and the filling material proper on the cavity walls. Sixty 120 micrometers-thick longitudinal sections from the teeth with the restorations in situ were studied by polarized light microscopy and microradiography. The glass ionomer cement caused by itself a narrow zone of increased radiopacity in the dentine cavity wall. The 'secondary caries' pattern consisted of a subsurface outer lesion and a subsurface wall lesion as observed previously in corresponding experiments with silicate fillings. Outer lesions in enamel were more frequent than with silicate cement. In the cementum all the experimental teeth showed outer lesions. The wall lesions extended only slightly beyond the level of erosion of the restorations. Between the wall lesions (in dentine) or outer lesions (in cementum/dentine) and the surface of the cavity wall, a zone of increased radiopacity was found, assumed to be due to reprecipitation of Ca and P promoted by release of fluoride from the filling material. PMID- 6928452 TI - Effect of toothbrush stimulation on temperature of gingival and alveolar mucosae. AB - Thermometry was used to study the effect of applying a toothbrush to three types of oral mucosae, in forty dental students. Brushing with an electric tooth brush resulted in an immediate fall in temperature, but 3 min later the temperature was significantly higher than before stimulation. The temperature changes were greater in gingival crevice and attached gingiva compared with alveolar mucosa. Moreover, it was found that a static application of the toothbrush produced temperature changes which were equal to those following a dynamic application. PMID- 6928453 TI - Let's face it. PMID- 6928454 TI - Biomechanical considerations in the surgical correction of mandibular deficiency. AB - A two-dimensional model is presented that allows calculation of mechanical advantage for the human masseter and temporalis muscles. Ten patients with high angle mandibular deficiency and vertical maxillary excess had greatly reduced mechanical advantages with an anticipated elevated muscle activity. Superior repositioning of the maxilla with mandibular advancement, however, increased the overall mechanical efficiency of the masticatory system. When compared with mandibular advancement alone, the bimaxillary procedure resulted in a 13% increase in the mechanical advantage of the temporalis muscle and a 21% increase for the masseter muscle. This model suggests that various surgical procedures designed to correct facial disharmonies may have either desirable or undesirable effects on jaw biomechanics and long-term stability. Biomechanical influences are important considerations for the clinician in planning surgical procedures to correct dentofacial deformities. PMID- 6928456 TI - Expectations of patients from orthognathic surgery. AB - Fifty-two patients were interviewed before and six months after corrective orthognathic surgery. These patients expected either a functional (39%), esthetic (17%), or combined functional and aesthetic (44%) outcome. All were satisfied with the functional change and 92% were satisfied with the esthetic change. Because almost all patients reported that the outcome of surgery was as expected, it seems unnecessary for the surgeon to be concerned about not recognizing hidden motives on the part of the patient. Some dissatisfaction was expressed with certain unexpected happenings during the surgical experience. If surgeons provide more detailed explanations of what to expect from the process of surgery, they can decrease this type of psychological trauma and increase the satisfaction of their patients. PMID- 6928457 TI - Clinical-pathological conference. Case 30, part 1. PMID- 6928455 TI - Results after mandibular advancement surgery: an analysis of 87 cases. AB - Clinical results and stability after mandibular advancement surgery were evaluated in a multi-institutional study of 87 individuals. Skeletal and dental stability were evaluated by a computer morphometric technique and clinical results were determined by recall of patients. Analyses of multiple variables were performed to determine factors that contributed to optimum treatment results or relapse, or both, after mandibular advancement. It was found that the mandible can be advanced successfully in all types of mandibular deficiency. Problems primarily related to surgical technique, such as postoperative condylar distraction, were consistently associated with relapse. Position of the proximal segment and the use of skeletal fixation were important in preventing relapse, but the value of suprahyoid myotomies and cervical collars was not proved. Significant postural changes of the head and cervical spine were observed after surgery. PMID- 6928460 TI - Temporary intraoperative covers for orthodontic appliances. PMID- 6928458 TI - Primary hemangioendotheliosarcoma of the mandible: review of the literature and report of case. AB - A rare case of hemangioendotheliosarcoma is presented. Our review of the literature confirms the difficulties we encountered in arriving at a correct clinical and pathologic diagnosis of this tumor, which seldom appears in the oral cavity, tends to be aggressive, and has a serious prognosis. PMID- 6928459 TI - Wiskott-Aldrich syndrome: review of literature and report of case. AB - Wiskott-Aldrich syndrome has been described. Other reports and studies of the syndrome have been compiled. Discussion of the incompletely understood pathogenesis and current treatment modalities are included with a differential diagnosis of related conditions. Although this syndrome is uncommon, it is not rare. The patient's susceptibility to infection and propensity to bleed makes early recognition and vigorous treatment an important and challenging task. It is hoped that this report will foster awareness of such patients and the complications involved in treatment. PMID- 6928461 TI - Angle location during transoral subcondylar osteotomy. PMID- 6928462 TI - Treatment of phenytoin-induced gingival hyperplasia by electrosurgery. AB - Many medications and combinations of medications are available for the control of epilepsy, but phenytoin continues to be the most effective agent for most patients. A common side effect of this drug is the development of moderate to severe gingival hyperplasia in tooth-bearing areas, which can contribute to problems of function, oral hygiene, appearance, and, eventually, loss of teeth. Excision by conventional means is technically difficult, time-consuming, may be associated with considerable loss of blood, and requires postoperative care, such as periodontal packing, that is impractical if not impossible for many patients, especially the severely mentally handicapped. We have described a technique of gingivectomy using an electrosurgical device in the hospital with the patient under general anesthesia that has produced good results for more than 15 years. This procedure has virtually eliminated the problems of conventional surgical excision with little or no postoperative sequelae. PMID- 6928463 TI - Effects of cranial radiation on hearing in children with acute lymphocytic leukemia. AB - We serially assessed the hearing sensitivity of 61 children with acute lymphocytic leukemia who were admitted to our Total Therapy IX study between December, 1975, and July, 1977. Their treatment included combined chemotherapy, 2,400 rads of cranial radiation, and intrathecal methotrexate. Subjects initially received an otologic examination and middle ear function testing. Audiometric testing was not done until ears were free of outer or middle ear pathology. If the child had no outer or middle ear disease, audiometric thresholds were obtained for the test frequencies: 500, 1,000, 2,000, 4,000, 6,000, and 8,000 Hz. Pure-tone thresholds were obtained before irradiation (61 patients) and at 6, 12, and 36 months thereafter (49, 46, and 22 patients, respectively). The median age at time of baseline testing was 10 years, 2 months. A paired sample test based on group data was used to test whether there were any significant changes from the threshold values at 6, 12, and 36 months after irradiation. Thresholds were not significantly affected for any test frequency at any test time. Assessments of individual audiograms indicated that none of the children had any significant reductions in hearing levels at the end of the third year after cranial irradiation. PMID- 6928464 TI - Clinical and occult testicular leukemia in long-term survivors of acute lymphoblastic leukemia. AB - Twenty-nine of 60 boys with acute lymphoblastic leukemia survived for more than 30 months and were potential candidates for discontinuation of therapy. Six patients developed overt clinical testicular leukemia: one at 34 months from diagnosis while receiving therapy and five at three to 17 months after therapy was stopped. Elective wedge biopsy of the testes has become part of the evaluation prior to discontinuation of therapy since 1977. Six of 18 boys had microscopic evidence of leukemic infiltration of the testes: four with diffuse involvement and two with focal clusters of leukemic cells. Testicular biopsy is recommended at the time of discontinuation of therapy and perhaps early in the course of the disease, although a negative biopsy does not exclude some focal lesions. The eventual outcome of those with occult testicular leukemia remains to be determined. PMID- 6928465 TI - Use of dental xeroradiographs in periodontics. Comparison with conventional radiographs. AB - An experimental intraoral dental xeroradiographic system was evaluated for its ability to image structures important in periodontal radiographic interpretation. On consenting dental patients, similar x-ray projections were made on (1) conventional film radiography and (2) experimental dental xeroradiographs. The resultant images were compared visually. In all categories examined the information provided by xeroradiography was either equal to or greater than that provided by conventional film radiographs. Intraoral dental xeroradiography appears to be a highly accurate, low-radiation, rapid, and convenient alternative to conventional intraoral radiography. PMID- 6928466 TI - Immunoglobulins in periodontal tissues. II. Concentrations of immunoglobulins in granulation tissue from pockets of periodontosis and periodontitis patients. AB - In recent years evidence in the literature has indicated that the immune response may play an important role in the initiation and progression of the periodontal diseases. A study was initiated to determine the IgA, IgG, and IgM concentrations in the granulation tissue removed from deep infrabony pockets of patients with periodontosis and advanced periodontitis. Comparison of mean immunoglobulin levels between the periodontosis and periodontitis groups revealed a statistically significant increase (P less than 0.05) for IgG in the granulation tissue from the periodontosis group. The possible implications of these findings are discussed. PMID- 6928467 TI - Immunoglobulins in periodontal tissues. III. Concentrations of immunoglobulins in dilantin-induced and idiopathic gingival hyperplastic tissues. AB - Immunoglobulin levels in both Dilantin-induced and idiopathic hyperplastic gingiva were determined and compared with the concentrations in normal gingival tissue. A statistically significant increase in IgG was found in Dilantin hyperplastic tissue, but no significant difference could be shown for idiopathic gingival hyperplasia. IgA levels did not differ significantly in the three types of tissue assayed. IgM was detected in 90% of the Dilantin hyperplastic gingival specimens assayed (mean GI = 1.2) and in 75% of the idiopathic hyperplastic tissue (mean GI = 0.7). This incidence of IgM detection was higher than that reported for normal and inflamed gingiva from periodontitis patients. The significance of these findings and possible correlation with the degree of tissue inflammation are discussed. PMID- 6928468 TI - Humoral immunologic responses in idiopathic juvenile periodontitis (periodontosis). AB - Humoral responses were examined in idiopathic juvenile periodontitis (IJP) including antibody titers to representative strains of the five groups of periodontosis-associated bacteria. Titers as determined by indirect immunofluorescence were compared in IJP, non-IJP family members, periodontitis and periodontally healthy subjects. Serum concentrations of IgG, IgA, IgM and IgE were also assayed. Antibody titers to the periodontosis-associated bacteria were generally low. Some disease specificity was observed in that titers to Groups II and III bacteria were highest in IJP. These titers in IJP were significantly higher (P less than 0.01) than in the other subjects. Titers to Group I bacteria were similar in all periodontal groups except the periodontally healthy subjects where titers were the lowest. Titers to Group I bacteria were significantly higher (P less than 0.01) than in the periodontally healthy subjects. Titers to Groups IV and V were uniformly low in all periodontal groups. Immunoglobulin concentrations of IgA, IgM and IGE were similar in IJP and non-IJP. The IgG concentrations in IJP, while within the normal range were significantly higher in IJP compared to non-IJP family members. PMID- 6928469 TI - Light microscopic and color television image analysis of the development of staining on chlorhexidine-treated surfaces. AB - Tooth staining with the use of chlorhexidine preparations is the major problem of long term application. Evidence suggests that the staining arises from a cationic/anionic interacation of chlorhexidine with components of certain dietary materials. The purpose of this in vitro study was to compare visually the development of tea and coffee staining on acrylic and tooth specimens treated with chlorhexidine and to follow the development of tea staining on perspex by light microscopy and color television image analysis. All specimens were maintained in their respective beverage for 5 days with test specimens removed three times a day and placed for 2 minutes in an 0.2% chlorhexidine solution. Both test tooth and acrylic specimens showed comparably and markedly increased staining by the beverages compared with control specimens. Color television image analysis of test specimens demonstrated more marked and rapid development of tea staining when studied on a daily basis. Microscopic examination revealed the staining to be made up of small particles of material which increased in size and coalesced with time. Again, marked differences were apparent in the stain on test and control specimens. The results of this in vitro method provided further evidence for a dietary aetiology to chlorhexidine staining and were consistent with clinical findings. Such a method may be useful to assess staining arising from the use of other anti-plaque agents. PMID- 6928470 TI - A new hypothesis of periodontal homeostasis. AB - A review of the experimental evidence evidence on marrow inhibition by implanted roots has shown that an inhibitory factor is present in all root surfaces. It is most marked in periodontally diseased roots and least in periodontally healthy roots. It is hypothesized that a "marked" amount would inhibit periodontal cells to the point where they could not resist the destructive effects of plaque, calculus and bacteria. A lesser or "moderate" amount would result in a more resistant periodontium. Finally, little or no inhibitor would also create a periodontium resistant to periodontal destruction but at the same time would remove restraints on the alveolar bone; the result would be invasion of the periodontal space and ankylosis to the root. PMID- 6928472 TI - Salivary antibodies in acute gingivitis. PMID- 6928471 TI - Conditions and pathological features of rapidly destructive, experimental periodontitis in dogs. AB - In order to analyze the conditions for rapidly destructive periodontitis and to describe the early histopathological changes and bone degradation, periodontitis lesions were produced in five male Beagle dogs, 8 to 12 months of age. Cotton floss ligatures were placed around the crowns of upper and lower third and fourth premolars for periods of 4, 7, 14, 21 days. The buccal gingival tissues, being slightly inflamed initially, were clinically scored for various symptoms of inflammation. Block biopsies of premorlars and the adjacent buccal periodontal tissues were taken and processed for light and electron microscopy. Depending on the ligature position in relation to the gingival margin (above, at, deep below) at the day of biopsy harvest, three groups of selected biopsies were formed, and randomly selected sections of these were used for various histometric measurements, for stereological estimation of the size and composition of the connective tissue infiltrate and the osteoclast density, and for general histopathological evaluation. The resulting data and observations implied that (1) onset and maintenance of this periodontitis lesion depend on subgingival ulceration, (2) rapid bone desstruction is the result of osteoclast activity stimulated by acute inflammation, and (3) bone degradation occurs independently of the loss of collagen fiber attachment and the apical migration of the junctional epithelium. PMID- 6928473 TI - Periodontal status of patients with abnormalities of the immune system. II. Observations over a 2-year period. AB - Patients with IgA deficiency and agammaglobulinemia were pair-matched to immunocompetent subjects by age and Plaque Index. Clinical examinations performed initially and after 2 years included the Plaque Index, Gingival Index, Periodontal Disease Index, caries experience (DMF-T) and full mouth radiographic surveys. Therapy during the 2-year period included oral hygiene instructions, prophylaxis and indicated restorative treatment. Immunodeficient patients manifested consistently lower levels of gingival inflammation than matched immunocompetent patients at both examination periods. Caries experience of immunodeficient patients was also less during the study interval, and five of these patients demonstrated DMF-T scores of zero. No developmental abnormalities, acute gingival or mucosal lesions, or attachment loss associated with periodontitis was observed in either group. PMID- 6928474 TI - Gingival recession in the lower incisor region of 15-year-old subjects. AB - A sample of 1,003 children, aged 15 years, were examined for prevalence of gingival recession. It was found that 17% had pseudo gingival recession and 1% had true recession. The highest degree of association with local etiological factors was that between recession and the width of keratinized gingiva; frenal pull was the second most highly associated factor followed by tooth arch relationship and the least association existed between plaque and gingival recession. There was no association between calculus and recession. PMID- 6928475 TI - Psychologic aspects of prosthodontic treatment for geriatric patients. PMID- 6928476 TI - The consumer speaks: how patients select and how much they know about dental health care personnel. PMID- 6928477 TI - The relationship of facial skin complexion to oral mucosa pigmentation and tooth color. PMID- 6928478 TI - Orthodontic extrusion: its use in restorative dentistry. AB - The technique described in this study demonstrates that the use of orthodontic extrusion can provide an alternative to extraction and extensive periodontal surgery. Selection of patients is an important aspect when considering this type of treatment. The crown-root ratio, as well as the root anatomy, if inadequate, may render this type of treatment inappropriate. The concept of a biologic width is discussed, and its application to forced eruption is described. PMID- 6928479 TI - Fracture strength of human teeth with cavity preparations. PMID- 6928480 TI - Comparison of three luting agents. AB - Three types of luting cements were compared for acidity, disintegration, and film thickness. The pH during setting of the two types of polycarboxylate cements exceeded 6 after 5 hours; that of the water-settable polycarboxylate cement was the highest, almost reaching neutral. The zinc phosphate cement reached pH 3.4 after 5 hours and 5.5 after 24 hours. All cements tested showed remarkably greater disintegration in the lactic acid solution than in the distilled water. The disintegration of the water-settable zinc polycarboxylate cement in distilled watter was about half that of the other cements. The disintegration in the lactic acid solution was approximately the same for all cements tested. The film thickness was smallest with the water-settable zinc polycarboxylate cement. PMID- 6928481 TI - An assessment of recent advances in external maxillofacial materials. AB - A variety of new materials representing several polymer classes and diverse fabrication procedures are now becoming available for use as external maxillofacial prostheses. Because of the availability of these materials, the severely disfigured patient can now be provided an opportunity to elad a near normal life in today's society. Remarkable advancements have been made in providing the patient with prostheses which feel and look more like skin. Progress has also been made in simplifying fabrication procedures, thus reducing cost. Much remains to be done in materials research. Processing time is still too long for most of the materials. Some of the materials give variable results in the quality and stability of the prostheses because of sensitivity to contaminants and to lab conditions and operator technique. Extrinsic coloration is extremely tedious and diffult with many of the products. The fitting and attachment of the prosthesis to the patient continues to need much improvement. Margins are difficult to mask even with the best materials. Large prostheses of most of the materials are much too heavy and are poorly retained. Staining of the prostheses by foods, cosmetics, and tobacco is a serious problem. The need for an improved material has been recognized by various government agencies and a few of the industrial suppliers of synthetic polymers. Additional advances are sure to result from these efforts. PMID- 6928482 TI - A flexible moulage for the fabrication of an orbital prosthesis. AB - A technique is disucssed by which a flexible three-piece moulage may be fabricated. This procedure is a useful aid in the modeling of an orbital prosthesis. It permits the continued transfer of a wax pattern from the moulage to the patient utilizing the tissue undercuts for the retention and stabilization of the pattern. The critical task of properly positioning the ocular prosthesis is simplified by the increased stability of the entire pattern. This is of the utmost importance since even a slight error in the alignment of the eye can entirely negate the effect of an otherwise accurate prosthesis. In addition, the retention of the wax pattern simplifies the carving procedure, and accurate detail is easily secured. The acrylic resin surface on which the final silicone prosthesis is cured has proven to be accurate. Well-adapted, thin margins of the facial prosthesis have been consistently obtained. PMID- 6928483 TI - Copperplated molds for facial prostheses. PMID- 6928485 TI - An overdenture survey: second report. PMID- 6928487 TI - The lively letters of Drs. Williams, Greene, Laskin, and Weinberg: myofascial pain dysfunction syndrome. PMID- 6928484 TI - Quantitative electromyographic diagnosis of myofascial pain-dysfunction syndrome. AB - The slopes of the V/T curves of masticatory muscles were determined in patients with MPD syndrome, and the changes in the slopes were observed prior to and during electrical muscle stimulation and splint therapy. The slopes of the V/T curves in patients with MPD syndrome were significantly steeper than those of the healthy subjects. In patients with MPD the slopes were decreased by electrical muscle stimulation of moderate duration and by insertion of the splint. These findings suggest that the most simple procedure for the diagnosis of MPD syndrome is to compare the slopes in MPD patients with those of healthy subjects. The observation of the changes in slopes during electrical muscle stimulation and splint therapy permits a more quantitative diagnosis of MPD syndrome. It also permits a quantitative measurement of improvement of symptoms in patients with MPD syndrome. PMID- 6928486 TI - Accurate mounting casts for complete dentures. AB - An accurate and efficient method to fabricate mounting casts for complete dentures has been presented. Well-made mounting casts are required to accurately transfer the jaw relation records made in the mouth to an articulator. PMID- 6928488 TI - The validity of temporomandibular joint radiographs using the head positioner. PMID- 6928490 TI - The validity of the radiographic method in the pretreatment review of dental claims. PMID- 6928489 TI - The relation between dental caries in the primary and permament dentition of the same individual. PMID- 6928491 TI - Evaluation of dental health education programs. PMID- 6928494 TI - The effects of patient-initiated phone confirmation strategies on appointment keeping at a hospital dental clinic. AB - This research reports the effectiveness of three interventions utilized to reduce broken appointments at a hospital dental clinic. Subjects in this study were 306 outpatients receiving dental care at Harborview Medical Center in Seattle. Prior to this investigation the clinic was not using any confirmation strategy; the no show rate was 30.2 percent (N=169). The first intervention was the traditional clinic-initiated phone reminder one day prior to the appointment; the second intervention made use of a mailed reminder, requesting patient-initiated confirmation by phone; and the third gave the same postcard reminder to the patient at the appointment desk, also requesting telephone confirmation. The two patient-initiated strategies were considered more consistent than the traditional phone reminders with the concept of patient responsibility for his own health care. The broken appointment rate for the phone reminder group was 23.5 percent, while for the postcard and the appointment card groups, the rates were 21.2 percent and 11.5 percent respectively. The rate for the appointment card group differed significantly from the phone reminder group and also from the baseline sample. PMID- 6928492 TI - Attitudes of health professionals involved in a school-based fluoride mouthrinse program. AB - A study was carried out to assess the attitudes of public health officials and dentists toward a school-based fluoride mouthrinse program administered in grades one through six in Kentucky. The responses were obtained by administering a questionnaire to health officials and dentists. The responses of the health directors indicate support for the program as a means of improving the overall dental care of children. These individuals do not feel a need for direct involvement in the daily operation of the program. They believe that adequately trained school personnel can implement the program. Dentists also view the fluoride mouthrinse program as an effective means of improving children's dental health. However, they feel that it should be part of a broad scope program which includes public health measures. Dentists are reluctant to support a program which they view as increasing the role of government in providing health care. PMID- 6928493 TI - Recruitment and participation in a school mouthrinse program. PMID- 6928495 TI - Assessing root caries in populations: the evolution of the root caries index. AB - This paper traces the history of the epidemiologic assessment of root caries over the past 30 years. This history clearly points out that a critical junction has been reached between the state-of-the art for the reporting of root caries and the demand placed on research and service components of the oral health system. If progress is to be made, it is imperative that a uniform reporting method for root caries be adopted. This paper introduces the Root Caries Index (RCI) as an index that should prove to be a feasible and utilitarian method for reporting root caries data in descriptive and analytic epidemiologic studies as well as assessing the results of preventive and treatment agents, clinical trials. The Root Caries Index represents, in the evolution of a root caries measurement method, a refinement of the delineation of the true intraoral "population at risk" to the disease process. The resulting index is a true attack rate for supragingival root caries lesions. This development should permit more meaningful comparison of populations, clearer interpretations regarding risk factors, and more precise assessment of preventive and treatment agents. PMID- 6928496 TI - Presidential address: 42nd annual meeting of the American Association of Public Health Dentists, Dallas, October 20, 1979. PMID- 6928498 TI - The Editor Emeritus' final squawk. PMID- 6928499 TI - [Prognostic factors in acute lymphoblastic leukaemia--with special consideration of pre-diagnostic duration of signs (author's transl)]. AB - It is concluded from the prognostic factors of acute lymphoblastic leukaemia, as far as they have become known up to now, such as initial leukocyte count, extent of organ infiltration, etc, that the pre-diagnostic duration of signs, representing a measure of the proliferation activity of the leukaemia cells, could also represent a relevant prognostic characteristic. A check conducted in 90 children treated between 1966--1975 yields a correlation only between a very short pre-diagnostic duration of signs (less than 2 weeks) and the duration of the first complete remission (as well as the survival time). However, even those prognostic factors which are already generally recognised, possess merely limited reliability, because they do not take the individual response to therapy into account. Hence, improvement of prognosis of the course of the disease can be expected only if the continuous decrease of the remaining population of blasts during the early phase of remission can be determined with greater accuracy than before. PMID- 6928497 TI - Update on FTC's rulemaking on KID-VID advertising. PMID- 6928500 TI - Genetic drift in a stock of laboratory mice. AB - Genetic drift in an outbred stock of CFLP mice was monitored for 6 years using genetic polymorphism for glucose phosphate isomerase (GPI) and the shape of the mandible as genetic markers. Statistically significant drift was found in both characters. The cause of this drift was not determined, though it could have arisen as a result of genetic sampling during hysterectomy derivation. The use of inbred strains is recommended on theoretical grounds of long-term genetic constancy is needed. PMID- 6928501 TI - Lymphoblastic leukaemia in a rabbit: a case report. PMID- 6928502 TI - The psychiatric treatment of alcoholism. PMID- 6928503 TI - Prophylactic treatment of alcoholism with lithium salts: a review. PMID- 6928504 TI - Ocular pathology associated with nonocular crushing injuries. PMID- 6928505 TI - Drug-resistant bacteria: implications for community hospitals and practicing physicians. PMID- 6928506 TI - Endocrine differentiation of the fetal rabbit ovary in culture. PMID- 6928508 TI - A couvade syndrome variant: case report. PMID- 6928507 TI - Anomalous phenotype in thymic acute lymphoblastic leukaemia. PMID- 6928510 TI - [Spectrophotofluorimetric enzymatic determination of total serum bile acids]. AB - A new enzymatic fluorimetric assay for the determination of total serum bile acids is described. The enzyme 3 alpha-idroxysteroid NAD oxireductase by oxydising the free OH in position 3 alpha of bile acid molecule, reduce NAD previously added. Afterwards the hydrogen of the generated NADH is transferred by a diaphorase to resazurin to yield the fluorophore resorufin proportionally to the amount of bile acids in the sample. The assay is simple, accurate, without bilirubin's influence and useful for a routine use because the analysis time is not different from the more common laboratory tests. PMID- 6928509 TI - Iatrogenic illness in a Community Mental Health Center. PMID- 6928511 TI - Alteration of the structure and function of rat liver chromatin by nutritional factors. PMID- 6928512 TI - Health care delivery; common problems throughout the world. PMID- 6928513 TI - Lactase deficiency. PMID- 6928514 TI - Privacy and confidentiality. PMID- 6928517 TI - Transversalis fascia hernioplasty. PMID- 6928516 TI - Bilirubin metabolism in obstructive jaundice. PMID- 6928518 TI - Total knee arthroplasty; update. PMID- 6928515 TI - Effect of furosemide on acute renal failure in dogs; induced by mercuric chloride. PMID- 6928519 TI - Multiple foci of colorectal carcinoma; argument for subtotal colectomy. PMID- 6928520 TI - Child abuse; prevention in teen-age parent. PMID- 6928521 TI - Electrocardiogram of the month. Question 283. PMID- 6928522 TI - Electrocardiogram of the month. Question 284. PMID- 6928524 TI - Hematuria secondary to perivesical tumors. PMID- 6928523 TI - Radiologic problem of the month. crumbled head of humerus. PMID- 6928526 TI - Legionnaires' disease after immunosuppression; response to erythromycin. PMID- 6928525 TI - Dramatic response of cancer to localized hyperthermia. PMID- 6928528 TI - Unusual imperforate anus. PMID- 6928527 TI - Tumors of small intestine; seek and ye shall find. PMID- 6928531 TI - Governmental regulations can be good, but also bad, or even tyrannical. PMID- 6928529 TI - Hypereosinophilic syndrome. PMID- 6928530 TI - The fight for continued medical privacy. PMID- 6928532 TI - Glycosylated hemoglobins. History, biochemistry, and clinical implications. PMID- 6928533 TI - Carcinoma of esophagus. Autopsy reports. PMID- 6928534 TI - Management of diabetic retinopathy. PMID- 6928535 TI - Reflux control after esophagogastrostomy. PMID- 6928536 TI - Statistics. Master or tool? PMID- 6928537 TI - Patients with biologic valve replacements. Short-term clinical follow-up with special reference to transient ischemic attacks with mitral prostheses. PMID- 6928539 TI - Primary lung carcinoma. Results with conservative resection in treatment. PMID- 6928540 TI - Right suprahepatic and left anterior subphrenic abscess. Direct transpleural drainage. PMID- 6928543 TI - Pelvic inflammatory disease. PMID- 6928542 TI - Dense calcaneus. PMID- 6928541 TI - Resection of giant benign fibrous mesothelioma of pleura. PMID- 6928538 TI - Heparinization during cardiopulmonary bypass. Simple calculator technique for control and reversal. PMID- 6928544 TI - Pituitary apoplexy following open-heart surgery. PMID- 6928545 TI - Torsion of appendix epididymis. PMID- 6928546 TI - Hidden asthmatic. Identification required for propranolol usage. PMID- 6928547 TI - Retained suture. Postprostatectomy complication. PMID- 6928550 TI - Risus Sardonicus, physician-philosopher of ancient Rome. Lost life and observations. PMID- 6928549 TI - Dextrocardia with total situs inversus. Radionuclide imaging and ultrasonography of liver and spleen. PMID- 6928548 TI - Anaerobic prostatic abscess. PMID- 6928551 TI - Vegetarianism. PMID- 6928552 TI - Schizophrenia: some problems for the nurse. PMID- 6928553 TI - A role for the nurse in caring for the individual suffering from rheumatoid arthritis. PMID- 6928554 TI - The nurse retraining programme in Yogyakarta, Indonesia. PMID- 6928555 TI - Changes in health care delivery which have affected the "role and "status" of health professionals. PMID- 6928556 TI - Year of the twenty-dollar gold piece. PMID- 6928558 TI - The symposium, part II. Looking toward the future. PMID- 6928557 TI - The symposium, part I. Fifty years of change. PMID- 6928559 TI - Challenge. PMID- 6928560 TI - The future of dental education. PMID- 6928561 TI - Tomorrow's attitudes. PMID- 6928563 TI - Welcome to 1999. PMID- 6928562 TI - Professionalism. PMID- 6928564 TI - Hospital dentistry and residencies. PMID- 6928565 TI - Wait for me!--I'm supposed to be leading the charge! PMID- 6928566 TI - TMI, oro-facial pain -- the "state of the art". PMID- 6928567 TI - The differential diagnosis of so-called temporomandibular joint disease. PMID- 6928568 TI - Multidisciplinary management of the craniomandibular syndrome. PMID- 6928569 TI - Mandibular position during deglutition. PMID- 6928570 TI - Case reports of TMJ repositioning to improve scoliosis and the performance by athletes. PMID- 6928571 TI - Comprehensive management of facial pain in a university-based center. PMID- 6928572 TI - The psychobiologic aspects of oral disease and oral pain. PMID- 6928573 TI - Trigeminal neuralgia--a new treatment concept. AB - A concept for the treatment of trigeminal neuralgia is presented. On the basis of distinctive pain patterns, localized areas of pathosis within the jawbones are detected and obilterated. To date, we have treated eight patients with idiopathic trigeminal neuralgia. All patients have experienced total or near total abatement of pain. PMID- 6928575 TI - Dental xeroradiography as an adjunct in the evaluation of oral cancer: a preliminary report. AB - This pilot study of an experimental dental xeroradiography imaging system involved twelve oral cancer clinic patients. Xeroradiographs were compared with conventional intraoral film radiographs, taken with similar x-ray projections. The new dental xeroradiographic system was judged superior for the imaging of both osseous and soft-tissue structures. Especially significant was the new imaging system's ability to portray early bone erosion not detectable with the conventional intraoral film technique. These results point to the need for controlled clinical evaluations of dental xeroradiography, in order to assess the full potential of this rapid, low-radiation imaging system in the evaluation of oral cancer. PMID- 6928576 TI - Angiolymphoid hyperplasia with eosinophilia (Kimura's disease). AB - Angiolymphoid hyperplasia with eosinophilia (Kimura's disease) primarily affects the skin of the head and neck and the oral mucosa. While the clinical picture is nonspecific, the variable microscopic tissue pattern often is diagnostic. The etiology is unknown, and treatment is unpredictable. A case is presented in which Kumura's disease was not suspected clinically prior to the biopsy. The patient responded to topical fluocinonide, and there was no evidence of an immunologic defect. PMID- 6928577 TI - Multiple hamartoma and neoplasia syndrome (Cowden's syndrome). AB - A case report involving a patient with Cowden's syndrome is presented. The patient's family is shown to be affected in a pattern consistent with an autosomal dominant form of transmission of this inherited disorder. The disorder can be diagnosed in its early stages by gingival and cutaneous manifestations; it is emphasized that the dentist is therefore perhaps the best-qualified health care professional to recognize the disease in its early stages and to alert the patient to be monitored for later predictable neoplasia which can perhaps be treated before metastasis develops. PMID- 6928578 TI - Juvenile fibromatosis affecting the jaws. Report of three cases. AB - Juvenile fibromatosis is a clinically aggressive but benign condition which does not commonly affect the jaws. Clinical and radiographic features are not specific, but diffuse lytic destruction of a portion of a jaw, especially the inferior border of the mandible, characterizes many cases. Histopathologic features are consistent and should be carefully observed to avoid a misdiagnosis of sarcoma. Three cases of juvenile fibromatosis affecting the jaws are reported; the patients were alive and well 9, 4, and 5 years, respectively, following therapy. PMID- 6928574 TI - Separation of a foreign body following cryosurgery. Report of a case. AB - A case is described where separation of a shrapnel fragment took place after cryosurgery for unrelated leukoplakia of the buccal mucosa. It is possible to accurately analyze such minute fragments by x-ray analysis. PMID- 6928579 TI - Cystic, melanotic ameloblastic fibroma with granulomatous inflammation. AB - A large mandibular tumor which had the cellular features of ameloblastic fibroma but was cystic and complicated by granulomatous inflammation is described. The epithelial component contained melanin. The pathogenesis of the cystic change is discussed, and the lesion is compared to the proposed papilliferous variant of this odontogenic neoplasm. PMID- 6928580 TI - Acute recurrent gingivitis. A clinical entity. AB - A typical case of a previously undescribed form of gingivitis which is self limiting and recurrent is discussed. The signs and symptoms include acute pain and swelling of interdental papillae with regional lymphadenopathy. As the disease progresses the localized swelling quickly spreads to the adjacent marginal and papillary gingiva. Ulceration is infrequent and without pseudomembrane formation or interdental cratering. We believe this to be a unique form of gingivitis and suggest the name acute recurrent gingivitis (ARG). PMID- 6928581 TI - Intraoral localized sarcoid lesion. AB - A case of an intraoral sarcoid lesion is presented. It is histologically similar to a lesion of generalized sarcoidosis, and the various clinical, radiographic, and laboratory modalities employed for a differential diagnosis are discussed. PMID- 6928584 TI - Tissue reactions following apical plugging of the root canal with infected dentin chips. A histologic study in dogs' teeth. AB - The object of the present work was to observe whether the condensation of a plug of infected dentin in the apical region, before the filling of a root canal, could show results similar to those found in the absence of contamination. The histologic analysis of the periapical tissues of dogs' teeth containing infected apical plugs showed results that were totally unfavorable, when compared to cases in which the plugs were absent. Such data do not encourage the use of dentin plugs for cases of contaminated root canals, at least until other experiments can better clarify the problem. PMID- 6928582 TI - Periapical response to dentin filings. A pilot study. AB - Vital maxillary canines of mature cats were intentionally instrumented through the foramen with No. 50 K-files. Dentin chips were packed into the apical opening in one tooth of each animal. In the contralateral tooth a dentin plug was not formed. Both root canals were then filled with gutta-percha. The animals were sacrificed at 3, 5, and 8 months. The results showed quicker healing characterized by minimal inflammation and cementum deposition in the specimens where dentin fillings were packed. PMID- 6928583 TI - Successful apexification technique in an immature tooth with dens in dente. AB - This is the first case report which documents the successful treatment by apexification of an immature permanent tooth with dens in dente. The patient, an 11-year-old boy in good health, presented with unilateral facial swelling and a "sore tooth." Clinical and radiographic examination revealed a partially erupted anomalous permanent canine with a radiolucent periapical area. After initial management with antibiotics, the anomalous structure within the canine was removed. Calcium hydroxide dressings were placed to facilitate apical closure. After 1 year the canal was filled with gutta-percha using a lateral condensation technique. PMID- 6928585 TI - Intraoral radiographic errors in films submitted for orthodontic consultation. AB - Radiographic surveys submitted by referring dentists to an orthodontic office for consultation are evaluated for their diagnostic value, and the observed errors are categorized as to technique, processing, and film-aging problems. The distribution of technique errors by anatomic location is identified. These results are compared with data from similar studies involving both dental and hygiene students. PMID- 6928586 TI - Xeroradiographic burnout of the hyoid bone. AB - This study shows that, depending on the amount of x-radiation used, a phenomenon called xeroradiographic "burnout" can be produced. Clinical cases are illustrated which show the disappearance of the hyoid bone with excessive amounts of x radiation. Xeroradiographic "burnout" occurs in the positive as well as in the negative mode. PMID- 6928587 TI - Development of a lingual mandibular bone cavity in an 11-year-old boy. AB - The following case report describes the development of a lingual mandibular bone cavity in a child. Previous cases of these cystlike mandibular defects have been, to the best of my knowledge, all observed in adults. Some of the literature and the different etiologies are reviewed. In this case report the first examination showed normal bone pattern in the mandible, and it was then possible to follow the development of the mandibular bone cavity for about 5 years. During this period the defect expanded until it reached what seems to be a mature stage. The radiographic technique used included lateral, occlusal, and posteroanterior projections. PMID- 6928588 TI - Double-rooted maxillary primary canines. PMID- 6928589 TI - Multiple dental anomalies. PMID- 6928592 TI - [de la Tourette's syndrome]. PMID- 6928590 TI - Differential diagnosis of various thrombocytopenias in childhood by analysis of platelet volume. AB - Platelet volume was measured in 20 healthy children, 18 patients with acute idiopathic thrombocytopenic purpura (ITP), 24 patients with chronic ITP, 22 patients with aplastic anemia, and 17 patients with acute leukemia in childhood. The authors compared the platelet volume of these patients by use of peak platelet volume (PPV or mode of the platelet volume), mean platelet volume (MPV) and the percent of large platelets (PLP) as parameters of the platelet volume, and then studied the relationship between the platelet volume and the specific gravity of platelets from these patients. The following was the platelet volume of normal children: PPV was 6.7 +/- 1.1 micrometer 3, MPV was 9.9 +/- 1.6 micrometer 3, PLP was 26.0 +/- 7.7%. All parameters of the platelet volume were remarkably large in chronic ITP, but only PPV was small in acute ITP. On the other hand, all parameters were small in both aplastic anemia and acute leukemia. In acute ITP and chronic ITP, the platelet volume returned to normal value after these thrombocytopenias disappeared. The platelet volume, however, still remained small even after remission in acute leukemia. There was better correlation between MPV and PLP than PPV and PLP. The density analysis of the platelets obtained from platelet-rich plasma (PRP) revealed that PLP in each medium (1.010 approximately 1.052) of normal PRP increased slowly in proportion to the increase of specific density of the media. On the contrary, most of large platelets obtained from the patients with acute ITP and chronic ITP were especially contained in the medium of high specific density (1.052). Large platelets of aplastic anemia and acute leukemia, however, were found in both low and high density media. The authors believe that analysis of the platelet volume using above mentioned three parameters would provide good weapon in early differential diagnosos of acute ITP, chronic ITP, and aplastic anemia. And these findings also may suggest the difference of thrombopoiesis between acute ITP and chronic ITP. PMID- 6928593 TI - Facing the issues. PMID- 6928594 TI - My philosophy on aging. PMID- 6928595 TI - Self-care applied to the aged. PMID- 6928591 TI - [Rare case of a heart lesion in a child with acute leukemia]. PMID- 6928596 TI - Ethics: what would you do? Abortion--moral or legal question. Part II. PMID- 6928597 TI - The child with a life-threatening illness. PMID- 6928599 TI - JCAH admits dentists, still denies membership to ANA. PMID- 6928598 TI - Ethics: what would you do? Abortion--moral or legal question. Part III. PMID- 6928601 TI - Topics in child neurology: born like a rag doll. PMID- 6928604 TI - [Unusual morphological picture of the blast crisis in chronic myeloleukemia]. PMID- 6928600 TI - New JCAH standard on quality assurance. AB - Genesis of the JCAH standard on quality assurance is described, application of the standard in hospitals is outlined, and expectations of the standard's influence on patient care are presented. PMID- 6928602 TI - [Results of 10 years of experiments with immunotherapy of acute leukemia with Polish BCG vaccine]. PMID- 6928603 TI - [Nuclear-cytoplasmic RNA transport in hemopoietic cells normally and in leukemias]. PMID- 6928605 TI - [Intraleukocytic lysozyme in acute leukemias]. PMID- 6928606 TI - Restoration of active transport of solutes and oxidative phosphorylation by naphthoquinones in irradiated membrane vesicles from Mycobacterium phlei. AB - Irradiation of the inverted membrane vesicles of Mycobacterium phlei with light at 360 nm inactivated the natural menaquinone [MK(9)(II-H)] and resulted in a loss of substrate oxidation, pH gradient, membrane potential, active transport of proline or calcium ions, and oxidative phosphorylation. Restoration of the protonmotive force and active transport occurred on addition of naphthoquinones such as vitamin K(1), menadione, or lapachol to the irradiated membrane vesicles. However, coupled phosphorylation was restored only by vitamin K(1). Menadione and lapachol did not act as uncoupling agents. The magnitude of the pH gradient and membrane potential in the quinone-restored system was a reflection of the rate of oxidation and was correlated with the rate of uptake of proline or Ca(2+). These results are consistent with the chemosmotic hypothesis proposed for the energy transducing mechanism for active transport and further demonstrate that the complete respiratory chain is not required to drive active transport. In contrast, the data suggest that in addition to the driving force (protonmotive force) necessary to establish oxidative phosphorylation, a specific spatial orientation of the respiratory components, such as the naphthaquinones, is essential for the utilization of the proton gradient or membrane potential or both. Bypass of electrons from the respiratory chain with menadione may explain the inability of this quinone to restore oxidative phosphorylation; however, lapachol restores oxidation by the same electron transport pathway as the natural menaquinone but fails to restore phosphorylation. Because all three quinones restore the protonmotive force, other factors that are discussed must be considered in understanding the mechanism of oxidative phosphorylation. PMID- 6928607 TI - Points of contact between histone H1 and the histone octamer. AB - The topography of the interaction between histone H1 and the histone octamer has been investigated. Bovine thymus nuclei or enzymatically fragmented chromatin were treated 1-ethyl-3(3-dimethylaminopropyl)carbodiimide, which catalyzes the formation of covalent bonds between residues of proteins in electrostatic contact. Histone H1-core histone dimers were identified and the segments of molecules participating in crosslinking were elucidated. The results demonstrate that the major histone H1-core histone dimer generated upon carbodiimide crosslinking of intact nuclei, chromatin, or mononucleosomes consists of the segment of histone H1 containing amino acids 74-106 crosslinked to the segment of histone H2A containing amino acids 58-129. Thus, the central globular region of histone H1 intimately contacts the histone octamer. Besides histone H1-H2 dimers, two other histone H1-containing crosslinked products were detected. In these instances, the segments of histone H1 molecules containing amino acids 1-72 were shown to participate in crosslinking. The histone H1 contact points defined here all occur within mononucleosomes and not between nucleosomes. These results permit the formulation of a testable model for the arrangement of histone H1 along polynucleosome chains. PMID- 6928610 TI - Monoclonal antibodies to estrophilin: probes for the study of estrogen receptors. AB - Splenic lymphocytes from a Lewis rat, immunized with purified estradiol-receptor complex of calf uterine nuclei, were fused with cells of three different mouse myeloma lines (P3-X63-Ag8, P3-NSI/I-Ag4-1, and Sp2/0-Ag14) to yield hybridoma cultures, 9% of which produced antibodies to the receptor protein (estrophilin). When cloned by limiting dilution, approximately 70% of the viable cultures secreted antiestrophilin antibody. When expanded in suspension culture, three clones derived from Sp2/0-Ag14 were found to secrete rat IgG (gamma 2a class), whereas seven other clones (from all three myeloma lines) secreted IgM. Monoclonal IgG shows comparable affinity for nuclear and extranuclear receptors, whereas IgM reacts preferentially with the nuclear form. Both classes of antibody react with unoccupied as well as with occupied receptor and do not interfere with its ability to bind to estradiol. By growing IgG-secreting clones in the presence of [35S]methionine, radiolabeled monoclonal antiestrophilin has been prepared. Unlike antiestrophilin antibody previously generated in the rabbit or the goat, which crossreacts with estrogen receptors from every animal species tested, antibodies produced by the Lewis rat and by hybridomas derived from its spleen cells react specifically with estrophilin from calf tissues. These monoclonal antibodies provide reagents for the application of immunochemical techniques to study estrogen receptors in calf target tissues. PMID- 6928609 TI - Serum stimulation of phospholipase A2 and prostaglandin release in 3T3 cells is associated with platelet-derived growth-promoting activity. AB - Sera from mouse, rat, and calf sources stimulate cellular phospholipase A2 activity (PLase; phosphatide 2-acylhydrolase, EC 3.1.1.4) and prostaglandin synthesis in 3T3 Swiss mouse fibroblasts, releasing up to 33% of biosynthetically incorporated [3H]arachidonic acid as hydrolysis products in 1 hr. The PLase stimulated by mouse serum exhibits specificity for arachidonic acid residues on phospholipids. It is stimulated 2.5-fold by 1.8 mM Ca2+ in the presence of 5 microM divalent cation ionophore A23187, consistent with a Ca2+-dependent enzyme possessing a cytoplasmic Ca2+ binding site. The percentage maximal PLase- and growth-stimulating activities of the three sera exhibit similar concentration dependencies, with the homologous (mouse) serum exhibiting the highest specific activities. Confluent 3T3 cells deplete PLase-stimulating activity from medium containing calf serum at a rate similar to the depletion of cell growth-stimulus activity. The PLase-stimulating activity in rat and mouse sera is derived from the leukocyte fraction of blood, presumably from platelets. In rat leukocyte lysates the PLase-stimulating activity exhibits properties similar to those reported for platelet-derived cell growth factors from rat and human sources- i.e., stability to exposure to 100 degrees C for 2 min or to pH 2 or pH 11, and cationic properties. Purified preparations of human platelet-derived growth factor also exhibit 3T3 PLase-stimulating activity. PMID- 6928612 TI - Antisickling activity of amino acid benzyl esters. AB - The sickling of homozygous sickel cells upon deoxygenation is inhibited in the presence of 3 mM L-phenylalanine benzyl ester (Phe-OBzl) or benzyl esters of other aromatic or hydrophobic amino acids. Phe-OBzl was found to permeate into erythrocytes rapidly, and the deoxygenated cells maintained considerable flexibility as measured by their ability to pass through 3-micron pores. The osmotic fragility of the cells was unchanged and the oxygen dissociation curve was shifted slightly from a 50% saturation values of 28.5 mm Hg to 31.0 mm Hg. At lower concentrations of Phe-OBzl some antisickling activity was seen. The Phe OBzl antisickling activity may involve both binding to deoxyhemoglobin S and modification of the erythrocyte membrane. This class of compounds has considerable potential as therapeutic agents for the treatment of sickle cell disease. PMID- 6928608 TI - Structure and function of carboxypeptidase A alpha in supercooled water. AB - The spectral and enzymatic characteristics of chromophoric derivatives of carboxypeptidase A alpha (EC 3.4.17.1) have been examined at subzero temperatures in supercooled water-in-oil emulsions. Substrate and temperature dependencies of enzyme kinetics indicated the existence of a solution-like enzyme phase that greatly extends the temperature range (greater than 60 degrees C) over which the activity of this enzyme can be measured. The emulsion spectra were virtually identical to those of solutions over a wide range of temperatures. Subzero temperatures (less than -10 degrees C) may induce changes of enzyme conformation but not of geometry at the site of the metal atom, nor do they adversely affect activity at any of the temperatures studied. Both structure and function of carboxypeptidase A alpha can be examined in supercooled water under identical reaction conditions. PMID- 6928613 TI - Examination of the conventional assumption of internal equilibrium within the states of a biochemical cycle. AB - If k is a representative "internal" rate constant between substates of a given biochemical state, and if alpha is representative of the rate constants of the biochemical cycle to which the state belongs, then cyclical activity at steady state pulls the substates out of internal equilibrium with each other by a factor of order 1 +/- O(alpha/k). For transients or steady isotonic contractions in muscle, the departures from internal equilibrium can be larger than this. The simplifying assumption that internal equilibrium is always maintained between the substates is justified at steady state, as a good approximation, if k/alpha greater than or equal to 100. In muscle contraction at maximum velocity, something like k/alpha greater than or equal to 500 is required. This problem is superficially similar to the question, in Eyring's rate theory, of the extent to which activated complex leads to products pulls the activated complex out of the assumed equilibrium with reactants. PMID- 6928611 TI - Thermal stability of type I and type III procollagens from normal human fibroblasts and from a patient with osteogenesis imperfecta. AB - Type I and type III procollagens were isolated from the medium of human fibroblast cultures in amounts adequate for examination by circular dichroism. Type I procollagen had a spectrum similar to that of type I procollagen and collagen from chicken embryos. The human type III procollagen showed a red shift not seen in type III collagen from calf skin. The midpoint (tm) for the helix-to coil transition for both human procollagens was 40 degrees C. the same tm values were obtained with type I and type III procollagens synthesized by fibroblasts from a patient with osteogenesis imperfecta. Type I procollagen synthesized by the patient's fibroblasts, however, tended to aggregate more readily than type I procollagen from normal human fibroblasts, apparently because of a structural alteration of the protein. PMID- 6928614 TI - Influenza defective interfering viral RNA is formed by internal deletion of genomic RNA. AB - The 3'- and 5'-terminal nucleotide sequences of the defective interfering (DI) RNAs present in a preparation of DI influenza virus were determined. It was found that all DI RNAs possessed identical terminal sequences for at least the first 13 nucleotides at the 5' end and at least the last 12 nucleotides at the 3' end. The sequence of the DI RNAs is (5')A-G-U-A-G-A-A-A-C-A-A-G-G-...-C-C-U-G-C-U-U-U-C-G C-U-OH(3'). In addition, the same sequences were present at the 3' and 5' termini of the viral polymerase genes (P1, P2, and P3) from which these DI RNAs originate. These results indicate that DI RNAs of influenzing virus are formed by an internal deletion of the genomic RNA. PMID- 6928615 TI - Photoaffinity labeling of rat androgen binding protein. AB - The photoinactivation and photoaffinity labeling of androgen binding sites present in cytosol prepared from intact sexually mature rat epididymides have been demonstrated by using unlabeled and [3H]-labeled 17 beta-hydroxy-4,6 androstadien-3-one. Both photoinactivation and photolabeling are dependent upon exposure to light. These processes are inhibited when photolysis is conducted in the presence of the photoinert compound 17 beta-hydroxy-5 alpha-androstan-3-one, suggesting that steroid-specific sites are involved in the reactions. The labeled steroid-specific product of photolysis is macromolecular with a molecular weight of 47,000 as determined by electrophoresis on polyacrylamide gels containing NaDodSO4, and proteinaceous because digestion of the cytosol with pronase before photolysis eliminates steroid-specific binding. After photolysis, the protein steroid complex has the ability to withstand dissociation during electrophoresis under denaturing conditions, and unlabeled 17 beta-hydroxy-5 alpha-androstan-3 one fails to displace the label from the complex. Thus, the binding of [3H]17 beta-hydroxy-4,6-androstadien-3-one to the cytosolic protein is covalent. This steroid-specific product is identified as an androgen binding protein of testicular origin by its comigration with native androgen binding protein on nondenaturing polyacrylamide gels and by its molecular weight which is within the range reported for androgen binding protein subunits. PMID- 6928616 TI - Ovalbumin is synthesized in mouse cells transformed with the natural chicken ovalbumin gene. AB - The entire chicken ovalbumin gene, accompanied by genomic DNA sequences flanking both termini of the gene and three copies of the herpes simplex virus thymidine kinase gene, has been cloned in plasmid pBR322. This recombinant plasmid was linearized and used to transform thymidine kinase-deficient mouse cells. Thymidine kinase-positive transformants were selected by their ability to grow in the hypoxanthin/aminopterin/thymidine (HAT) medium. The entire ovalbumin gene integrated into high molecular weight DNA within all the transformants and retained its original sequence organization. In all of the transformants examined, a protein identified as chicken ovalbumin by immunoreactivity was detected within the cells. It is estimated that between 1000 and 100,000 molecules of chicken ovalbumin were produced per mouse cell in each of these transformants. Our results demonstrate that the mouse cellular machinery can be utilized to accurately express genetic information encoded in a cloned gene from a different eukaryotic organism into its specific protein product. PMID- 6928617 TI - Phospholipids as the molecular instruments of ion and solute transport in biological membranes. AB - Partition studies have established that phospholipids generally have the capabilities to mediate the transmembrane transport of the full range of ions and solutes that physiologically cross biological membranes. The list of transportable species includes cations, anions, amino acids, citric acid cycle intermediates, nucleotides, and sugars. Phospholipid-mediated transport can be readily modulated by altering the phospholipid mixture or by addition of detergents, nucleotides, divalent metals, proteins, peptides, or ring compounds. Containment of phospholipid within channels in protein appears to be the precondition for the formation of the micellar structure requisite for solute transport. Phospholipid-mediated transport is postulated to be a central feature of energy coupling, membrane-spanning systems, and membrane-bound, phospholipid requiring enzymes. PMID- 6928619 TI - Structure of potato inhibitor complex of carboxypeptidase A at 5.5-A resolution. AB - The complex of the 39-amino inhibitor (potato) of bovine carboxypeptidase A (carboxypeptidase; peptidyl-L-amino-acid hydrolase, EC 3.4.12.2) was crystallized in space group P32. There are two protein-inhibitor complexes in the asymmetric unit. These crystals exhibited pseudo-P3221 symmetry due to twinning about the a3 axis. Heavy atom difference Patterson maps and rotation functions indicated, however, that the noncrystallographic twofold axis that relates these two complexes is nearly coincident with the a3 axis. Consequently, to a good approximation at low resolution, the space group of the complex is P3221 and the effects of twinning may be ignored. The structure was solved by using multiple isomorphous replacement and molecular replacement techniques. At 5.5-A resolution, the multiple isomorphous replacement map was readily interpretable in terms of the known native carboxypeptidase A structure plus extra density around the active site. The position of this extra density is consistent with the binding mode for extended substrate proposed from earlier model building studies with the native enzyme (Lipscomb, W.N., Hartsuck, J.A., Reeke, G.N., Quiocho, F.A. Bethge, P.H., Ludwig, M.L., Steitz, T.A., Muirhead, H. & Coppola, J.C. (1968) Brookhaven Symp. Biol. 21, 24-90). PMID- 6928618 TI - Diphtheria toxin: nucleotide binding and toxin heterogeneity. AB - We have used flow dialysis to demonstrate binding of ATP and related compounds to diphtheria toxin. The results define a new site on the toxin molecule (the P site), which has distinctly different properties from the NAD+-binding site of the fragment A moiety. The relative affinities of various compounds for the P site are similar to their capacities to inhibit toxin attachment to cell surfaces and its action on cells. This suggests that the P site may correspond to the binding site for cell surface receptors. Affinity of nucleotides for the toxin depends strongly on the number of phosphates, although both nucleoside and phosphate moieties contribute to the interaction. A substantial fraction of the toxin in any given preparation did not bind ATP in a rapidly reversible manner and was not retained on ATP-Sepharose. This fraction, which varied in magnitude from preparation to preparation, was isolated and shown to contain an endogenous, firmly bound nucleotide or nucleotide-like compound. The presence of this compound may explain some of the physical heterogeneity within individual preparations of purified toxin as well as variations in physical and biological properties among various preparations. PMID- 6928620 TI - Insulin receptor synthesis and turnover in differentiating 3T3-L1 preadipocytes. AB - A density-shift method is described for analyzing insulin receptor synthesis and turnover in cultured cells labeled with "heavy" amino acids (2H, 13C, and 15N). Solubilized newly synthesized heavy and old "light" receptors are separated by isopycnic banding on CsCl gradients and then quantitated. Insulin receptor synthesis and turnover were studied by this technique in 3T3-L1 preadipocytes which undergo an increase in insulin binding capacity during differentiation. The results indicate that the increase in insulin binding capacity is a consequence of new receptor synthesis, that the insulin receptor has a relatively short half life (6.7 hr), and that an increased rate of receptor synthesis contributes to the increase of insulin receptor level during differentiation. PMID- 6928621 TI - Acetone metabolism in mice: increased activity in mice heterozygous for obesity genes. AB - Mice were found to convert acetone to lactate at appreciable rates. The conversion of acetone to gluconeogenic precursors could provide additional glycolytic intermediates that would allow the more complete utilization of lipid stores and increase survival time during starvation. In mice that were starved for 3 days or were provided with acetone in the drinking water the acetone metabolizing pathway was induced to levels severalfold normal. Mice heterozygous for obesity-producing mutations, either obese (ob/+) or diabetes (db/+), showed induction of the activity of this pathway to a significantly higher degree than did homozygous normal (+/+) mice of the same strain. This more effective conversion of acetone to lactate exhibited by heterozygous mice could account for their prolonged survival on a starvation regimen compared to that of normal homozygotes. The rate-limiting step in the pathway appears to be the conversion of acetone to a hydroxylated derivative. The enzyme system effecting this conversion is an NADPH-requiring microsomal oxygenase found in the liver. PMID- 6928622 TI - Analysis of rat heart in vivo by phosphorus nuclear magnetic resonance. AB - High-resolution 31P nuclear magnetic resonance spectra at 73.83 MHz are reported for rat heart in vivo. In live rats, it was possible to observe the cardiac content of ATP, phosphocreatine, and Pi. Only a small amount of whole-blood 2,3 diphosphoglycerate was observed in the spectra, precluding the possibility that blood phosphate compounds were masking the spectra of cardiac phosphate compounds. The 31P nuclear magnetic resonance spectra of in vivo and perfused rat hearts were similar and support the utilization of the perfused rat heart as a model system for studying high-energy phosphate metabolism of the heart in vivo. The dynamic flux of high-energy phosphate compounds was investigated by subjecting the rat to respiratory arrest. In this experiment, the heart followed the classic metabolic pattern known to occur during cardiac arrest; phosphocreatine and then ATP decreased in concentration while Pi increased in concentration. The 31P nuclear magnetic resonance analysis of rat heart in vivo is demonstrated to be a practical and feasible method for studying cardiac high energy phosphate metabolism. PMID- 6928623 TI - Cell-cell recognition in yeast: purification of Hansenula wingei 21-cell sexual agglutination factor and comparison of the factors from three genera. AB - Trypsin digestion of Hansenula wingei 21-cells releases a protein (21-factor-T) that inhibits the agglutination of 21-cells by purified 5-agglutinin obtained from 5-cells by subtilisin digestion [Crandall, M. A. & Brock, T. D. (1968) Bacteriol. Rev. 32, 139-163]. We have purified this inhibitor 415-fold by ion exchange chromatography, affinity adsorption to 5-cells, and gel permeation chromatography. The material shows a diffuse band, on polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate, with an apparent M(r) of 27,000. It has a pI of 3.8, is rich in acidic amino acids, contains 5% mannose and a trace of glucosamine, and is stable to reducing agents but is inactivated by heat. Zymolyase (beta1-->3-glucanase) digestion of 21-cells releases a similar inhibitor that, after purification, has a larger size than 21-factor-T. This 21 factor-Z appears to contain an additional portion that may serve to anchor 21 factor in the cell wall. Haploid cells of the yeasts Pichia amethionina and Saccharomyces kluyveri also show a constitutive sexual agglutination, and little or no crossreactivity is observed in heterologous mixtures. The agglutination factors in all three genera, however, have parallel properties; one cell type of each pair is heat stable and is inactivated by reducing agents (H. wingei 5 cells, P. amethionina alpha-cells, and S. kluyveri 16-cells), and the other is heat labile and is unaffected by reducing agents H. wingei 21-cells, P. amethionina a-cells, and S. kluyveri 17-cells). Because S. kluyveri 16-cells respond to Saccharomyces cerevisiae alpha-factor with the typical morphogenetic change of a mating half-reaction, the heat-stable agglutinin appears related to the S. cerevisiae a mating type and the heat-labile factor to the S. cerevisiae alpha mating type. PMID- 6928625 TI - Interaction of 16 alpha-[125I]iodo-estradiol with estrogen receptor and other steroid-binding proteins. AB - This communication describes the synthesis of 16 alpha-[125I]iodo-estradiol (125I E2) with specific activities greater than 1000 Ci/mmol (1 Ci = 3.7 x 10(10) becquerels). We show that it binds to the same specific estrogen receptor sites as does [3H]estradiol and that it does so with an affinity that is indistinguishable from that for the latter steroid. This is true for receptor obtained from calf uterus and from a pool of human mammary carcinomas. There is no significant binding of 125 I-E2 to the testosterone-estradiol-binding globulin of human plasma. 125I-E2 also binds tightly to anti-estradiol antibodies raised against estradiol derivatized at carbons 3, 6, and 17. Finally, we show that unlabeled I-E2 is an active estrogen in vivo as demonstrated by its ability to increase uterine weight in ovariectomized rats. PMID- 6928626 TI - Carboxybiotin translocation mechanisms suggested by diffraction studies of biotin and its vitamers. AB - Biotin is a coenzyme that fixes CO2 for transfer in a family of carboxylase, decarboxylase, and transcarboxylase enzymes. Their enzyme reactions involve two basic steps during which a carboxybiotinyl intermediate forms at one site and translocates to a second (distinct) site for CO2 transfer. Our diffraction studies of biotin and its vitamers suggest that translocation involves rotation about one, or at most two, bonds in biotin's valeryl chain. The rotations are energetically economical gauche in equilibrium trans rotations about the two valeryl bonds nearest the biotin bicyclic ring. They move a carbon atom of a CO2 moiety bound at N-1' approximately 7 A, a distance in accord with spectroscopic measurements of one of the biotin enzymes. From our studies we infer that sulfur in biotin imparts to the valeryl chain a conformational variability necessary for bond rotation and, hence, translocation between catalytic sites. PMID- 6928624 TI - Delipidation of bacteriorhodopsin and reconstitution with exogenous phospholipid. AB - Solubilizations of the purple membrane from Halobacterium halobium with the detergent Tritain X-100 followed by gel filtration in deoxycholate solution gave bacteriorhodopsin that was more than 99% free from endogenous lipid. The delipidated bacteriorhodopsin was reconstituted with exogenous phospholipids to form vesicles which on illumination efficiently translocated protons. The direction of proton pumping was from the outside to the interior of the vesicles, indicating that the orientation of bacteriorhodopsin in the vesicles was opposite to that in the bacterial membrane. This orientation was confirmed by cleavage of the carboxyl terminus of the protein by proteolysis from the outside of the vesicles. PMID- 6928627 TI - Orthorhombic two-dimensional crystal form of purple membrane. AB - A new two-dimensional crystal form of purple membrane has been obtained in vitro. It is produced by the joint use of a cationic detergent, dodecyltrimethylammonium chloride, and the nonionic detergent, Triton X-100. It primarily forms large, rolled-up sheets that look like needles in the light microscope. Liposomes and tubes are also observed. The absorption maximum of the new form of purple membrane is blue-shifted by 6 nm and its density is slightly lower than the natural form of purple membrane. The new form of purple membrane is orthorhombic with space group p22121 and cell dimensions 57.6 x 73.5 A. Four molecules of bacteriorhodopsin occupy the unit cell with an area per molecule close to that found in the native p3 structure. The projected structure to 6.5-A resolution was determined by electron microscopy and diffraction. It shows an identical molecular structure to that of the p3 form and determines the position of the polypeptide boundary. PMID- 6928629 TI - Meiotic synthesis of testis histones in the rat. AB - The distribution and synthesis of the testis-specific variants of histones H1 and H2B, TH1 and TH2B, respectively, and of the somatic histones were studied in rat testis cells. Rat testis cells were labeled in vivo with intratesticular injections of [3H]lysine. The cells and nuclei were then separated into different developmental classes by velocity sedimentation and the histones were analyzed. TH1 and TH2B, as well as the somatic histones, were present in spermatocytes and round spermatids, but none of them were detectable in elongated spermatids. The synthesis and nuclear accumulation of TH1 and TH2B took place throughout pachytene, as well as in earlier stages, but not in the round spermatids. In addition, there was synthesis during pachytene of a histone that migrates electrophoretically with H2A. However, somatic histone synthesis, with the possible exception of H2A and H2B, was not detectable at the pachytene stage. In vivo treatment of rats with hydroxyurea reduced DNA synthesis in the testis to 1% of control values and significantly reduced the synthesis of H3, H2B, H2A, and H4, with the greatest effect being on H3 and H4. However, the hydroxyurea treatment did not significantly decrease the synthesis of TH1, H1, or TH2B. These results prove that the synthesis of several histones during the meiotic prophase is not dependent upon concurrent S-phase DNA synthesis. PMID- 6928630 TI - Identification of an adhesion factor for chondrocytes. AB - The attachment of chondrocytes to collagen substrates is stimulated by serum but not by fibronectin. The active material in serum was partially purified and was shown to be a protein by its sensitivity to trypsin and heat and its chromatographic properties. This factor, which we have named chondronectin, is distinct from fibronectin and does not stimulate fibroblast attachment. Because material with similar attachment-enhancing activity is produced by chondrocytes and is extractable from cartilage, chondronectin may be a chondrocyte-specific attachment protein. PMID- 6928628 TI - Organ chemiluminescence: noninvasive assay for oxidative radical reactions. AB - In situ and perfused rat livers showed a spontaneous chemiluminescence of 7-12 counts/sec . cm2 (corresponding to 7-12 x 10(3) photons/sec . cm2); chemiluminescence was increased up to 30 times by infusion of exogenous hydroperoxides. The chemiluminescence of the perfused liver was oxygen dependent. Ethyl, t-butyl, and cumene hydroperoxides were almost equally effective in inducing light emission in the perfused liver. Glutathione release and chemiluminescence showed a parallel increase upon hydroperoxide supply to the perfused liver. A partial spectral analysis of the chemiluminescence of the perfused liver showed a predominance of red-light-emitting species, presumably arising from the singlet oxygen dimol-emission peaks. Many side reactions derived from the complex free radical sequence of lipid peroxidation could afford the chemistry leading to light emission, which represents only about 10(-14) of the utilization of peroxide. PMID- 6928632 TI - Polypeptide composition of squid neurofilaments. AB - Neurofilaments, 10 nm in diameter, from the axoplasm of the squid Loligo pealei have been isolated by a combination of sonication and Millipore filtration. The presence of neurofilaments during the isolation procedure was confirmed by negative staining and transmission electron microscopy. By use of this technique, which results in minimal or no chemical alteration of the native neurofilament proteins, it was shown that actin (43,000 daltons) and tubulin (56,000 daltons) are physically separable from intact neurofilaments. The neurofilament-rich retentate contained two major proteins of 200,000 and 63,000 daltons and larger polypeptides. PMID- 6928631 TI - Arrest and metastasis of blood-borne tumor cells are modified by fusion of plasma membrane vesicles from highly metastatic cells. AB - B16 mouse melanoma sublines in culture spontaneously shed intact plasma membrane vesicles. These vesicles can be fused with the plasma membrane of cells from homologous and heterologous B16 sublines by using polyethylene glycol and phytohemagglutinin-P. Fusion of vesicles from a highly metastatic subline (F10) that localizes exclusively in the lung with cells from a poorly metastatic subline (F1) significantly increased the ability of F1 cells to become arrested in the lung and form metastases in this organ. In contrast, fusion of F1 vesicles with F10 cells did not alter the ability of vesicle-modified cells to localize in the lung or form lung metastases. F10 vesicle-modified F1 cells reverted to their original arrest behavior and metastatic capacity after removal of F10 vesicle components from the plasma membrane. The changes in the arrest and metastatic behavior of F10 vesicle-modified F1 cells were highly highly specific. Vesicles from other B16 sublines that are poorly metastatic and show limited localization in the lung (F1, FLLr, and F10Lr) did not modify the arrest behavior and metastatic capacity of FU cells. These results suggest that the differences in the abilities of the F1 and F10 sublines to localize in the lung are determined by differences in cell surface properties. PMID- 6928634 TI - Induction of plasminogen activator secretion in macrophages by electrochemical stimulation of the hexose monophosphate shunt with methylene blue. AB - Resident peritoneal macrophages were obtained from untreated mice and were cultured in medium 199 with or without 5% acid-treated fetal bovine serum. Three hours after harvesting, redox compounds--i.e., methylene blue, methyl viologen, or nitro blue tetrazolium--were added to the cultures of adherent cells. After 1 hr, the cells were washed and culturing was continued in the absence of redox compounds. The effects of the redox compounds were tested by assaying for hexose monophosphate (HMP) shunt activity and for plasminogen activator secretion, and the results were compared with the effects induced by phagocytic stimuli. Methylene blue caused a concentration-dependent stimulation of the HMP shunt, whereas methyl viologen and nitro blue tetrazolium were ineffective. Shunt stimulation by methylene blue was followed, after a lag of 2-4 days, by plasminogen activator secretion. The rate of secretion was dependent on the methylene blue concentration used. Methyl viologen and nitro blue tetrazolium were again ineffective, whereas phagocytosis of zymosan or sheep erythrocytes, which stimulates the HMP shunt, induced plasminogen activator secretion at rates similar to those induced by methylene blue. These results add further evidence to our hypothesis that the HMP shunt-dependent metabolic burst is involved in macrophage activation. Because methylene blue mimics the action of zymosan it appears that shunt stimulation by itself initiates the activation process independently of phagocytosis. PMID- 6928635 TI - A selective inhibitor of cell proliferation from normal serum. AB - A factor in normal serum that selectively and reversibly inhibits proliferation of cells in culture has been enriched 160-fold from calf serum by sequential ammonium sulfate precipitation, gel filtration, and lectin-affinity chromatography. DNA synthesis of normal (but not transformed) rat hepatocytes, human lymphoblast lines, and mitogen-stimulated murine spleen cells is inhibited by greater than 90%, and Vero, murine myeloma, MELC, and a human colon carcinoma cell line to a lesser extent. Growth of other cell lines tested was not affected. Responsive cells are arrested apparently in G1 by this inhibitor, the effect of which is maximal by 24 hr and is spontaneously reversible thereafter unless it is renewed. The active fraction is a protein that migrates with the alpha 2 globulins; it is not a lipoprotein, and it is of high apparent molecular weight. PMID- 6928633 TI - Induction of differentiation of human and murine myeloid leukemia cells in culture by tunicamycin. AB - Tunicamycin, an antibiotic that specifically blocks the synthesis of N acetylglucosamine-lipid intermediates and thereby prevents glycosylation of glycoproteins, induced differentiation of both human (HL-60) and murine (M1) myeloid leukemia cell lines in culture. At 0.1-1.0 microgram/ml, it induced differentiation of both HL-60 and M1 cells, characterized by increase in phagocytic cells and changes to resemble mature myeloid cells. Fc receptors were also induced in M1 but not in HL-60 cells; induction of intracellular lysozyme activity was not detected in either HL-60 or M1 cells. With this concentration of tunicamycin, there was marked decrease in rate of incorporation of radioactive glucosamine into macromolecules and a decrease in the rate of DNA synthesis. These data show that glycosylation of cellular proteins has an important role in maintaining these myeloid leukemia cells in an undifferentiated state in culture. The results also indicate that induction of phagocytosis in both HL-60 and M1 myeloid leukemia cells and of Fc receptors in M1 cells does not require continued synthesis of the oligosaccharide portions of cellular proteins by the lipid linked pathway. PMID- 6928636 TI - Model for capping derived from inhibition of surface receptor capping by free fatty acids. AB - When low concentrations (2-5 mole %) of cis unsaturated free fatty acids (group A) are intercalated into lymphocyte plasma membrane, capping is inhibited. No effect is seen with trans unsaturated or saturated fatty acids (group B). The capping inhibition is reversible with increasing doses of extracellular calcium. Fluorescence photobleaching recovery has shown that the group A free fatty acids do not inhibit the receptor immobilization associated with patch formation, but inhibit the final energy-dependent movement of the patched receptors into a cap. We have also shown that the group A free fatty acids cause a shift in membrane bound calcium to the lipid phase from probable protein-associated sites. We have incorporated these findings into a model for capping and membrane-cytoskeletal interactions. PMID- 6928637 TI - Fusion of liposomes with mitochondrial inner membranes. AB - A procedure is outlined for the fusion of mixed phospholipid liposomes (small unilamellar vesicles) with the mitochondrial inner membrane, which enriches the membrane lipid bilayer 30-700% in a controlled fashion. Fusion was initiated by manipulation of the pH of a mixture of freshly sonicated liposomes and the functional inner membrane/matrix fraction of rat liver mitochondria. During the pH fusion procedure, liposomes became closely apposed with and sequestered by the inner membranes as revealed by freeze-fracture electron microscopy. After the pH fusion procedure, a number of ultrastructural, compositional, and functional characteristics were found to be proportionally related: the membrane surface area increased; the lateral density distribution of intramembrane particles (integral proteins) in the plane of the membrane decreased whereas the particles remained random; the membrane became more buoyant; the ratio of membrane lipid phosphorus to total membrane protein increased; the ratio of membrane lipid phosphorus to heme a of cytochrome c oxidase increased; and the rate of electron transfer between some interacting membrane oxidoreduction proteins decreased. These data reveal that liposomal phospholipid was incorporated into the membrane bilayer (not simply adsorbed to the membrane surface) and that integral membrane proteins diffused freely into the laterally expanding bilayer. Furthermore, the data suggest that the rate of electron transfer may be limited by the rate of lateral diffusion of oxidoreduction components in the bilayer of the mitochondrial inner membrane. PMID- 6928638 TI - A cytoplasmic clock with the same period as the division cycle in Xenopus eggs. AB - In most species the cell cycle is arrested in the unfertilized egg. After fertilization the cell cycle is reestablished and a rapid series of cleavages ensues. Preceding the first cleavage in Xenopus the egg undergoes a contraction of its cortex, called the "surface contraction wave," which can be visualized by time-lapse cinematography. This wave of contraction is propagated in a circular manner from the animal pole to the equator. We have found that eggs prevented from cleaving by treatment with antimitotic drugs undergo a sequence of periodic surface contraction waves timed with the cleavage cycle in untreated eggs. In addition, artificially activated eggs, which fail to cleave presumably for lack of a functioning centriole, undergo the same periodic contractions. No nuclear material is required for the periodic waves because a separated egg fragment, produced by constricting a fertilized egg, still undergoes contraction waves with the same period as the cleaving nucleated fragment. These results demonstrate that some expression of the cell cycle persists in the absence of any nuclear material or centrioles, suggesting to us that a biological clock exists in the cytoplasm or cortex of vertebrate eggs, which may be involved in timing the cell cycle. PMID- 6928640 TI - Differential lectin binding to cellular membranes in the epidermis of the newborn rat. AB - Three fluorescein-labeled lectins have been shown to exhibit specificity for the surface of cells in different layers of the epidermis in the newborn rat. An isolectin from seeds of Bandeiraea simplicifolia with specificity for alpha-D galactosyl end groups labeled the basal and lower spinous cells; a lectin from Ulex europaeus exhibiting specificity for alpha-L-fucosyl units outlines the surface of spinous cells, and a second lectin from B. simplicifolia, with specificity for N-acetyl-D-glucosamine, labels the cornified cells. Appropriate blocking experiments have confirmed the specific nature of the binding. PMID- 6928641 TI - Lentropin: a factor in vitreous humor which promotes lens fiber cell differentiation. AB - An activity has been identified in chicken vitreous humor which stimulates embryonic chicken lens epithelial cells to elongate and specialize for lens crystallin synthesis. The activity is heat-labile and is destroyed by treatment with trypsin or agents that reduce disulfides. Gel filtration and ultrafiltration analyses indicate that it has an apparent molecular weight of approximately 60,000. Its properties differ from those of an activity present in serum which also can promote lens fiber cell formation in vitro. We call this material "lentropin" and suggest that it is responsible for stimulating lens fiber cell formation in vivo and, consequently, plays an important role in determining the shape and polarity of the lens. PMID- 6928639 TI - DNA crosslinking and cytotoxicity in normal and transformed human cells treated with antitumor nitrosoureas. AB - Normal (IMR-90) and simian virus 40-transformed (VA-13) human embryo cells were treated with antitumor nitrosoureas, and the effects on cell viability and cell DNA were compared. All six nitrosoureas tested were more toxic to VA-13 cells than to IMR-90 cells as measured by decrease in cell proliferation or in colony formation. The nitrosoureas capable of generating alkylisocyanates produced a smaller difference between the cell types than did derivatives lacking this capacity. DNA damage was measured by alkaline elution in cells treated with four chloroethylnitrosoureas. Whereas VA-13 cells exhibited dose-dependent interstrand crosslinking, little or none was detected in IMR-90 cells. The IMR-90 cells, however, exhibited at least as much DNA-protein crosslinking as did VA-13 cells. The results can be interpreted in terms of a possible difference in DNA repair between the cell lines. PMID- 6928642 TI - Phylogenetic analysis of the mycoplasmas. AB - The phylogenetic relationships between the mycoplasmas and bacteria have been established from a comparative analysis of their 16S rRNA oligonucleotide catalogs. The genera Mycoplasma, Spiroplasma, and Acholeplasma arose by degenerative evolution, as a deep branch of the subline of clostridial ancestry that led to Bacillus and Lactobacillus. Thermoplasma has no specific relationship to the other mycoplasmas; it belongs with the archaebacteria. PMID- 6928643 TI - Triplicated alpha-globin loci in humans. AB - We have identified 12 individuals who are heterozygous for a chromosome with three alpha-globin genes. We determined the presence of the third alpha-globin locus by restriction endonuclease digestion and hybridization with alpha-globin cDNA probes. The three alpha-globin loci resided in an elongated fragment on digestion with EcoRI, BamHI, and Xba I, and the third locus was present in an additional 3.7-kilobase fragment on digestion with Hpa I, Sac I, and Bgl II. The locations of the restriction sites are compatible with a nonhomologous crossover mechanism producing the triple alpha loci. The frequency of the triple alpha loci was 0.0036 in American blacks and less than 0.004 in Sardinians, but was higher in Greek Crypriots (0.05). Individuals with five alpha-globin genes (alpha alpha/alpha alpha alpha) apparently showed no clinical or hematologic abnormalities. PMID- 6928644 TI - Antibody-independent activation of the alternative complement pathway by measles virus-infected cells. AB - When HeLa cells acutely infected with measles virus were incubated in a mixture containing only the six proteins of the alternative pathway of complement activation (C3, factors B and D, beta 1H, C3b inactivator, and native properdin) without antibody, there was activation of the alternative pathway as shown by progressive uptake of 125I-labeled C3b onto the cell surface. This C3b uptake was blocked by EDTA and was not shown by uninfected cells. The rate of 125I-labeled C3 uptake by infected cells was the same in the absence and presence of properdin; however, when antiviral IgG was bound to the cell surface, the rate of C3 uptake was increased in the presence of properdin. Significant 125I-labeled C3 uptake was first detectable when cells were studied at 12 hr after infection, when cells expressed viral polypeptides on their surface. There was also progressive uptake of 125I-labeled C3 onto measles virus-infected cells incubated in human serum depleted of both IgG and C4. Hence, the human alternative pathway of complement activation can be initiated on the surface of measles virus infected cells independent of IgG antibody. However, lysis of the infected cells only occurs when antiviral antibody is present. PMID- 6928645 TI - Immunoselection of mutants deficient in cell surface glycoproteins encoded by murine erythroleukemia viruses. AB - We have described a heterogeneously processed glycoprotein with an apparent molecular weight of 55,000 (gp55) that is encoded by the Friend spleen focus forming virus, an acute erythroleukemia virus [Dresler, S., Ruta, M., Murray, M.J. & Kabat, D. (1976) J. Virol. 30, 564-573]. Several lines of evidence suggest that a small proportion of the gp55 in infected cells is located on the surface membranes. First, different nonproducer cell lines infected with cloned Friend spleen focus-forming virus were efficiently killed in the presence of complement by cytotoxic antisera that react with gp55. Furthermore, a clone of cells selected for resistance to the cytotoxic antibody synthesized an altered intracellular form of gp55. This immunoselection procedure appears to also be useful for isolating glycoprotein mutants of other RNA tumor viruses. Analysis of cell surface proteins labeled with [125I]iodine supported the idea that gp55 occurs on the plasma membranes. However, the cell surface gp55 had more highly processed oligosaccharides than the majority of the gp55, which occurs within the infected cells. In addition, we have found that leukemia cells from mice infected with the erythroleukemic Rauscher virus complex contain a membrane glycoprotein that appears similar to the gp55 encoded by Friend spleen focus-forming virus. The encoding of similar glycoproteins by independently isolated acute erythroleukemia viruses suggests that these glycoproteins may be important in leukemogenesis. PMID- 6928646 TI - Demonstration of a specific mitochondrial isovaleryl-CoA dehydrogenase deficiency in fibroblasts from patients with isovaleric acidemia. AB - To study the enzymatic basis of isovaleric acidemia, we have developed assay methods for isovaleryl-CoA and butyryl-CoA dehydrogenases that measure the amount of tritium released from the respective [2,3-3H]acyl CoAs. Because assay of these enzymes in human fibroblast homogenates was subject to interference by nonspecific reactions, we have isolated mitochondria from cultured skin fibroblasts by protease treatment, homogenization, and differential centrifugation. By using this assay method with these isolated mitochondria, we have demonstrated a specific deficiency of isovaleryl-CoA dehydrogenase [isovaleryl-CoA: (acceptor) oxidoreductase, EC 1.3.99.10] activity in cultured skin fibroblasts from five patients with isovaleric acidemia. In contrast, mitochondrial butyryl-CoA dehydrogenase [butyryl-CoA: (acceptor) oxidoreductase, EC 1.3.99.2] activity in these cells was preserved at normal levels. These results have been reproduced by using the conventional dye reduction assays. These observations give further support to the hypothesis that isovaleryl CoA is dehydrogenated by a specific enzyme and that isovaleric acidemia is due to a deficiency of this enzyme. PMID- 6928647 TI - Association of coronary atherosclerosis with hyperapobetalipoproteinemia [increased protein but normal cholesterol levels in human plasma low density (beta) lipoproteins]. AB - Most patients with coronary artery disease do not have elevated plasma or low density lipoprotein (LDL) cholesterol. To test whether the protein moiety of LDL, LDL B, might be a parameter to identify ischemic heart disease, the plasma cholesterol, triglyceride, LDL cholesterol, and LDL B were measured in 100 consecutive patients undergoing cardiac catheterization. On the basis of coronary angiography, these patients were divided into two groups: group I, 31 patients without, and group II, 59 patients with significant coronary artery disease. Although cholesterol, triglyceride, and LDL cholesterol levels were all significantly higher in group II, discriminant analysis indicated that LDL B concentrations most clearly separated the two groups. In group I (noncoronary), LDL B was 82 +/- 22 mg/100 ml, whereas in group II, LDL B was 118 +/- 22 mg/100 ml. The B protein level in group I was similar to other normal groups studied (35 asymptomatic male physicians, 83 +/- 11 mg/100 ml; 90 normolipidemic medical students, 72 +/- 17 mg/100 ml). The results therefore indicate that not only does LDL B better separate coronary and noncoronary groups than other lipid parameters studied, but also, among those with coronary artery disease, there exists a group with normal LDL cholesterol but with levels of LDL B protein similar to those observed in type II hyperlipoproteinemia. The explanation for the altered LDL composition observed in this group remains to be elucidated. PMID- 6928648 TI - Evidence for an important physiological role for calcitonin. AB - We propose that calcitonin, secreted in response to the intake of food, aids in routing calcium, obtained by intestinal absorption, into bone fluid. Here calcium is temporarily stored in combination with phosphate for return to the extracellular fluid (blood) during intervals between oral intakes of calcium. The net result is a conservation of calcium postprandially and a decrease in parathyroid hormone-induced bone destruction during subsequent fasting periods. Evidence for this postulate is provided in the following six sequential steps from the time a calcium-containing meal is consumed until that portion of calcium stored in bone fluid is utilized during fasting periods to aid in plasma calcium maintenance. (i) Calcitonin secretion is stimulated by feeding and subsequent digestive processes. (ii) Postprandial secretion of calcitonin restricts the efflux of calcium from bone fluid to blood, thereby maintaining parathyroid hormone (PTH) secretion. (iii) In thyroid-intact individuals, both PTH and calcitonin are secreted postprandially and act in concert on calcium homeostasis. (iv) Calcitonin actively moves phosphate into bone and prevents its loss from bone fluid to blood. (v) Postprandial storage of calcium with phosphate occurs in bone fluid of thyroid-intact individuals. (vi) This labile storage form of calcium is the first to be utilized during fasting periods. In the absence of partial disruption of this storage mechanism, rapid development of pathological bone conditions would not be expected because PTH action permits the extended utilization of bone calcium for plasma calcium control. However, augmentation of osteopenic conditions could be expected if long-term low calcium intake were accompanied by a malfunction of this calcitonin-induced system for calcium storage. PMID- 6928649 TI - Covalent labeling of protein components of the sodium channel with a photoactivable derivative of scorpion toxin. AB - Azidonitrobenzoyl mono[125I]iodo scorpion toxin can be covalently attached to its receptor site in electrically excitable neuroblastoma cells or synaptosomes by photolysis. A polypeptide of Mr approximately 250,000 is specifically labeled in neuroblastoma cells. Labeling is blocked by unlabeled scorpion toxin and by depolarization. This polypeptide is not labeled in a variant neuroblastoma clone lacking voltage-sensitive sodium channels. Polypeptides of Mr approximately 250,000 and Mr approximately 32,000 are specifically labeled in synaptosomes. This labeling is also blocked by unlabeled toxin and by depolarization. These results identify specific polypeptides of Mr approximately 250,000 and Mr approximately 32,000 that are components of the sodium channel. PMID- 6928650 TI - Interplexiform cell in cat retina: identification by uptake of gamma [3H]aminobutyric acid and serial reconstruction. AB - After intravitreal injection of gamma-[3H] aminobutyric acid (GAB), 2% of the neurons at the outer margin of the inner plexiform layer were intensely labeled. Reconstructions of these neurons from serial electron microscope autoradiograms showed that they are interplexiform cells, which synapse on bipolar processes in the outer plexiform layer and on amacrine and bipolar processes in the inner plexiform layer. PMID- 6928652 TI - Correlation between relaxation and automaticity in embryonic heart cell aggregates. AB - Diastolic depolarization in cardiac muscle is due to a decline in potassium permeability that has been ascribed to removal of intracellular free calcium. A continued decline in tension during the pacemaker potential might therefore occur. In this study, contractile responses of chicken embryonic heart cell aggregates are recorded with a photodiode. Photodiode output is well correlated with the position of the aggregate's edge. Movements of different edges are synchronous, and their amplitude and duration vary appropriately during experimental maneuvers that alter the magnitude and duration of contractile force. Edge movement during relaxation has two phases, a rapid phase lasting about 100 msec and a slow phase that may last over 10 sec. The slow phase is not due to viscoelasticity because its time course does not depend on the magnitude or duration of the initial deformation. The rate of relaxation is correlated with the rate of depolarization during the pacemaker potential. Reduction in automaticity during cooling, spontaneous variation, and overdrive pacing are associated with impairment of the slow component of relaxation. Electrophysiological evidence suggests that the diastolic potassium permeability of the aggregates is controlled by intracellular calcium. A possible explanation for the correlation between the slope of the pacemaker potential and the slow component of relaxation is that both phenomena reflect a common physiological process-i.e., the removal of free calcium from the cytoplasm. PMID- 6928653 TI - Amino acid side chain conformation in angiotensin II and analogs: correlated results of circular dichroism and 1H nuclear magnetic resonance. AB - [1-Sarcosine,8-isoleucine]angiotensin II (Sar-Arg-Val-Tyr-Ile-His-Pro-Ile) has been shown to be a potent antagonist of the pressor action of angiotensin II. With a view to increase half-life in vivo of this peptide, the amino acid residue at position 4 (tyrosine) or position 5 (isoleucine) was replaced with the corresponding N-methylated residue. This change drastically reduced the antagonistic properties of this analog. The present work was therefore undertaken to investigate the effect of N-methylation on overall conformation of these peptides and to determine the conformational requirements for maximum agonistic or antagonistic properties. Conformation studies were carried out by circular dichroism and proton nuclear magnetic resonance spectroscopy in aqueous solution as a function of pH. The results indicated that: (i) angiotensin II and [1 sarcosine,8-isoleucine]angiotensin II gave practically identical spectroscopic data; and (ii) N-methylation in either position 4 or position 5 resulted in remarkable changes in the peptide backbone and a severe limitation in rotational freedom of side chains in tyrosine, isoleucine, and histidine residues. However, rotational restriction of the tyrosine side chain was found to be less pronounced in [1-sarcosine,4-N-methyltyrosine,8-isoleucine]angiotensin II than in [1 sarcosine,5-N-methylisoleucine,8-isoleucine]angiotensin II. Thus, these results suggest that: (i) the backbone and side chain structure of a potent angiotensin II antagonist should resemble that of the hormone, angiotensin II, so that it can mimic the hormone in recognizing and binding with the receptor on the cell membrane; and (ii) greater impact of N-methylation in position 5 on the overall conformation of these peptides points to the controlling influence of position 5 (isoleucine) in aligning the residues in the central segment (tyrosine-isoleucine histidine) of angiotensin II and its potent agonist and antagonist analogs in a nearly extended structure. Any change in this arrangement may lead to reduced biological activity. PMID- 6928651 TI - Spatial frequency specific interaction of dot patterns and gratings. AB - Adaptation to patterns of paired random dots produces loss of contrast sensitivity to sinusoidal luminance gratings oriented perpendicularly to the dot pair direction. This adaptation loss is spatial frequency- and orientation specific and varies with dot-pair separation in a manner predictable from the Fourier spectra of the stimuli and observed characteristics of the visual system. These results support the idea that the visual system acts as a periodicity analyzer with known restrictions and cannot be accounted for by a feature detector model. When the bars of the test gratings are aligned in the dot-pair direction, there is no adaptational loss at any frequency despite the fact that the adaptation pattern contains significant spectral power at all frequencies in this orientation. This lack of adaptation may be due to inhibitory interactions among channels or to nonlinear effects within local receptive fields. PMID- 6928654 TI - A subpopulation of cultured human promyelocytic leukemia cells (HL-60) displays the formyl peptide chemotactic receptor. AB - The chemotactic peptide N-formyl-Nle-Leu-Phe-Nle-Tyr(125I)-Lys (formyl 125I peptide) binds in a saturable manner to human promyelocytic leukemia cells (HL 60) grown in suspension culture. The binding is of high affinity (50% binding at 0.4--0.75 nM), is rapid (half-time at 22 degrees C = 10 min), is enhanced by divalent cations, but is poorly reversible. These characteristics are similar to those of the formyl peptide chemotactic receptor on human peripheral blood neutrophils. The relative potencies of a series of synthetic peptides in inhibiting binding to the HL-60 cell receptor correlate closely with their potencies in inhibiting binding to the peripheral neutrophil receptor. However, whereas all peripheral human neutrophils display the receptor, only a subpopulation of the cultured cells will bind and internalize tetramethylrhodamine-labeled N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys. This subpopulation is distinct from the rest of the culture, displays morphological characteristics typical of well-differentiated promyelocytes, and appears to account for all of the measured fromyl 125I-peptide binding. Binding of both 125I-labeled and tetramethylrhodamine-labeled formyl peptide increases in response to treatment of the culture with polar compounds that induce cell differentiation. Cells from the differentiated culture demonstrate a chemotactic response to N-formyl-Nle-Leu-Phe Nle-Tyr-Lys, whereas cells from the undifferentiated culture do not. PMID- 6928655 TI - Posttranslational modification of elongation factor 2 in diphtheria-toxin resistant mutants of CHO-K1 cells. AB - We have identified two types of mutants of Chinese hamster ovary cells in which the unique ADP-ribose attachment site in elongation factor 2 (EF-2) is altered, thereby rendering them resistant to diphtheria and Pseudomonas toxins (TOXR). The first is mutant in the gene for EF-2 and possesses a permanently altered, TOXR gene product. The second lacks a component of a posttranslational modification system that converts TOXR EF-2 to the toxin-sensitive (TOXS) state. We postulate that this modification system is involved in the conversion of a single histidine residue in EF-2 to the specific target of toxin-catalyzed ADP-ribosylation, the novel amino acid X. We have designated the second type MOD- mutants. The missing of nonfunctional component in the MOD- mutants can be restored by hybridizing them with either normal TOXS cells or with EF-2 structural gene mutants. The TOXR EF-2 from MOD- mutants is also converted to toxin sensitivity in vitro by incubation with extracts of TOXS or EF-2 gene mutant cells in the presence of an energy-generating system. Our results demonstrate that EF-2 can be synthesized and released from ribosomes in a toxin-resistant form and then converted to toxin sensitivity by posttranslational modification. PMID- 6928656 TI - Kinetics of membrane internalization and recycling during pinocytosis in Dictyostelium discoideum. AB - Internalization and recycling of plasma membrane during pinocytosis in Dictyostelium discoideum was analyzed quantitatively. A labeling technique was used by which [3H]galactose could be enzymatically bound to and released from the plasma membrane. Label internalized with the plasma membrane was no longer accessible to enzymatic release and could therefore be distinguished quantitatively from label remaining on the cell surface. Internalization of labeled membrane components was measured as a function of pinocytotic uptake. Direct experimental evidence for membrane recycling was obtained by demonstrating that previously internalized label reappeared at the plasma membrane. The experimental data agree with a kinetic model requiring that a shuttle of membrane between two membrane compartments leads to the same surface concentration of label in both. The two compartments consist of the plasma membrane and of cytoplasmic vacuolar membranes; their relative membrane surface areas are 1 and 0.5, respectively. One surface area equivalent of the plasma membrane is internalized during a pinocytotic uptake amounting to 15% of the cell volume. At the observed rate of pinocytosis, this occurred once every 45 min. The average size of the primary pinosomes, as weighted according to their contribution to pinocytotic uptake, was calculated to be about 0.6 microns. PMID- 6928658 TI - Synthesis of zona pellucida proteins by denuded and follicle-enclosed mouse oocytes during culture in vitro. AB - During growth of the ovarian follicle, the mammalian oocyte becomes surrounded by an acellular coat called the zona pellucida. Whether the zona pellucida originates from the oocyte, surrounding follicle cells, or both has remained an unresolved issue. In experiments described here, denuded and follicle-enclosed mouse oocytes at various stages of growth were isolated and cultured in vitro in the presence of either [(35)S]methionine or [(3)H]fucose in order to determine the site of synthesis of the three, recently identified, zona pellucida proteins, ZP1, ZP2, and ZP3 [Bleil, J. D. & Wassarman, P. M. (1980) Dev. Biol., in press]. Approximately 1.5% of the [(35)S]methionine, and as much as 45% of the [(3)H]fucose, that was incorporated into trichloroacetic acid-insoluble material by denuded or follicle-enclosed oocytes during a 12-hr culture period was found associated with zonae pellucidae removed from the cultured oocytes. Incorporation of [(35)S]methionine into zona pellucida proteins was depressed to less than 1/50th when denuded oocytes were cultured in the presence of puromycin, and secretion of zona pellucida proteins by denuded oocytes was demonstrated by pulse chase experiments. Sodium dodecyl sulfate/polyacrylamide gel electrophoresis of [(35)S]methionine- and [(3)H]fucose-labeled proteins present in oocytes, zonae pellucidae, and follicle cells revealed that denuded oocytes synthesize and secrete zona pellucida proteins, whereas no evidence was obtained to suggest that follicle cells synthesize these proteins. Denuded oocytes, ranging in diameter from 48 to 68 mum, incorporated both [(35)S]methionine and [(3)H]fucose into zona pellucida proteins during culture in vitro, whereas zonae pellucidae removed from fully-grown oocytes (85 mum) were not radiolabeled to a significant extent. After culture of denuded or follicle-enclosed oocytes for 12 hr, more than 95% of the [(3)H]fucose incorporated into oocyte proteins was found in ZP1, ZP2, and ZP3, indicating that the zona pellucida proteins are the major class of proteins glycosylated during oocyte growth. These results provide biochemical evidence supporting the idea that the zona pellucida originates from the mammalian oocyte itself, rather than from the surrounding follicle cells. PMID- 6928657 TI - Synthesis of adult myosin light chains by embryonic muscle cultures. AB - Myosin light chain synthesis has been analyzed in cultures of fast and slow muscles from chicken and quail embryos. Synthesis was assayed by [35S]methionine incorporation and two-dimensional electrophoresis of total cell extracts. Our results show that differentiated cultures of embryonic anterior latissimus dorsi and pectoral muscles synthesize proteins that comigrate on two-dimensional gels with the five myosin light chains of adult fast (pectoral) and slow (anterior latissimus dorsi) muscle. Partial proteolytic digestion and peptide analyses further confirm the identity of these proteins as adult light chains. Cultures of dividing myoblasts do not synthesize any of these fiber type isozymes, and synthesis of the isozymes is initiated at myoblast fusion. Also, myogenic clones drived from single myoblasts differentiate to synthesize these five myosin light chains, indicating that individual myoblasts have the potential to express the synthesis of all fiber type light chain isozymes. We conclude that the primary events in muscle differentiation include the initiation of synthesis of the entire set of adult fast and slow myosin light chain isozymes. The developmental and physiological implications of these results for the establishment of fiber type specificity are discussed. PMID- 6928659 TI - Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma. AB - The pattern of in vitro anchorage-independent growth of tumor cells from the murine UV-2237 fibrosarcoma correlated with their ability to produce experimental metastasis in vivo. When seeded into 0.3% Noble agar semisolid medium, cells of metastatic clones developed into larger tumor colonies at a faster rate than did cells of clones with low metastatic potential. Furthermore, when tumor cells were plated into 0.6% Noble agar, colony development by cells of low metastatic potential clones was almost completely restricted. Tumor cells from the heterogeneous parent UV-2237 fibrosarcoma were plated into dishes containing 0.6% agar semisolid medium. In separate experiments, 16 colonies were isolated 2 weeks thereafter and were established as individual cell lines in monolayer cultures. All of these cell lines produced experimental metastases as determined by in vivo lung colony assay. The data suggest that anchorage-independent growth of UV-2237 tumor cells in 0.6% Noble agar semisolid medium is selective and permits the isolation of metastatic subpopulations. PMID- 6928660 TI - Distribution and activity of endogenous lectin during myogenesis as measured with antilectin antibody. AB - Antibodies to electrolectin, a lectin endogenous to embryonic skeletal muscle, have been used to study the distribution of electrolectin during myogenesis in L6 cells and rat primary muscle cultures. Antibody binding is highest to mononucleated cells and is low to myotubes in both systems. Binding is much lower to fibroblasts in the primary cultures. Binding appears to be on the surface of these cells, although evidence is presented for there being binding on the inside of cells as well. When observed on myotubes, binding is generally associated with highly stained patches and in some instances is near regions where fusion may be occurring, In L6 cells, binding sites can be exposed by treating mononucleated cells with trypsin. These results are discussed in terms of their possible role in myogenesis and synaptogenesis. PMID- 6928661 TI - Role of minimization of chemical distances between amino acids in the evolution of the genetic code. AB - The allocation of codons in the genetic code makes possible a moderate minimization of the chemical distances between pairs of neighboring amino acids in the code. However, the code is neither a global nor a local optimum with respect to distance minimization. These findings do not support the physicochemical postulate that distance minimization was a major factor shaping the evolution of the genetic code. They agree with the coevolution theory, which proposes that genetic code evolution was predominantly determined by the concession of codons from precursor to product amino acids in an expansion of the code to accommodate new varieties of amino acids, with distance minimization playing a subsidiary role in deciding the choice of codons to be acquired by the product amino acids from the codon domains of the precursor amino acids. PMID- 6928662 TI - IgM antibodies induce the production of antibodies of the same specificity. AB - Injection in normal mice of IgM antibodies against sheep erythrocytes or dextran, in the form of an immune serum depleted og IgG, induces direct plaque-forming cells of the same specificity as the injected antibodies. The response is 10--70 times higher than the background plaque-forming cell titer of untreated control mice. Nanogram amounts of IgM induce a detectable response, and a ceiling is reached with a few hundred nanograms of monoclonal IgM. The inducing agent is not residual antigen: (i) treatment of the injected material and the recipients with dextranase abolishes the immunogenicity of dextran, but not the response to anti dextran IgM; (ii) monoclonal IgM specific for sheep erythrocytes or trinitrophenyl likewise induces plaque-forming cells of the respective specificity, but variant hybridoma products (in which the light chain is that of the myeloma parent) are inactive. In normal mice, IgM-induced antibody responses were observed with antibodies to both thymus-dependent and thymus-independent antigens, but such could not be induced in athymic (nude) mice. Because the mechanism underlying this phenomenon would operate also in a normal immune response and, presumably, in the normal dynamic state of the immune system of unstimulated animals, a network regulation among the elements of the immune system itself is implied. PMID- 6928663 TI - Complete amino acid sequence of pooled papain-solubilized HLA-A, -B, and -C antigens: relatedness to immunoglobulins and internal homologies. AB - Pooled, papain-solubilized HLA-A, -B, and -C antigens, derived from a large number of individuals and comprising several allelic forms, have been subjected to amino acid sequence determination. Despite the heterogeneity of the material, a main sequence representing all of the 273 amino acid residues could be established. The primary structure encompasses two immunoglobulin-like disulfide loops. The single carbohydrate moiety is attached to asparagine-86. Computer analyses demonstrated that the COOH-terminal one-third of the sequence, called H3, display statistically significant homology with members of the immunoglobulin family. The NH2-terminal two-thirds of the molecule, called H1 and H2, are not significantly homologous to any of the immunoglobulin sequences. However, H1 and H2 exhibit a distant relatedness to each other but no obvious similarity to the H3 region. PMID- 6928664 TI - Primary structural studies of an H-2L molecule confirm that it is a unique gene product with homology to H-2K and H-2D antigens. AB - Radiochemical methodology has been used in the isolation and preliminary biochemical characterization of the murine H-2Ld major histocompatibility complex gene product. The radiolabeled molecule was isolated by immunoprecipitation from the glycoprotein fraction of detergent-solubilized H-2d tumor cells. Six major CNBr fragments were isolated from a papain fragment of this molecule; three of the fragments are connected by disulfide bonds. Due to the high degree of homology between major transplantation antigens, it was possible to align the fragments by comparison of their amino acid sequences to that of the H-2Kb gene product. Of the positions available for comparison between H-2Ld and H-2Kb, H 2Dd, and H-2Kd gene products, 61 out of 80 (78%), 45 out of 55 (82%), and 12 out of 15 (80%), respectively, are identical. Differences between the Ld and Kb and Dd molecules are distributed throughout the amino acid sequence. These data indicate that the H-2Ld gene product is a molecular species distinct from, but homologous to, the H-2K and H-2D gene products. PMID- 6928665 TI - Cellular and subcellular localization of 1,25-(OH)2-vitamin D3 in rat kidney: comparison with localization of parathyroid hormone and estradiol. AB - Results of thaw-mount autoradiographic studies of kidney obtained 1--3 hr after a single injection of 1,25-(OH)2-[3H]vitamin D3 to rats showed strong nuclear concentration of radioactivity in podocytes and cells of distal tubules, including the pars convoluta, macula densa, and pars recta. Intermediate nuclear concentration was found in cells of the thin limb of Henle's loops, whereas weak or no nuclear uptake was seen in cells of the proximal tubules. In contrast, after injection of 3H-labeled parathyroid hormone or [3H]estradiol, mainly cells of the proximal tubules were labeled; after 3H-labeled parathyroid hormone, apical cytoplasmic uptake of radioactivity was seen most strongly in the proximal part of the proximal tubules, whereas, after [3H]estradiol, weak nuclear concentration was seen in cells throughout the proximal tubules. The results are consistent with the concept that synthesis of 1,25-(OH)2-vitamin D3 occurs in the proximal tubules under stimulation of parathyroid hormone or estradiol (or other hormones) and that the major site of action of 1,25-(OH)2-vitamin D3 is in the distal tubules. PMID- 6928666 TI - Free radicals and inflammation: superoxide-dependent activation of a neutrophil chemotactic factor in plasma. AB - The intravenous administration of superoxide dismutase (superoxide:superoxide oxidoreductase, EC 1.15.1.1) to animals with induced inflammation suppresses the inflammatory response and inhibits leukocyte infiltration into the challenged site, suggesting that neutrophil-generated superoxide reacts with an extracellular precursor to generate a substance chemotactic for neutrophils. Plasma exposed to superoxide in vitro becomes potently chemotactic. The appearance of chemotactic activity is inhibited by superoxide dismutase but not by catalase. The chemotactic factor does not stimulate superoxide production or degranulation in neurtrophils. Intradermal injection of superoxide-treated plasma or of a superoxide-generating system causes heavy infiltration of neutrophils to the injection site but does not cause overt signs of inflammation. The chemotactic factor consists of a chloroform-extractable component bound to serum albumin. The superoxide-dependent chemotactic factor appears to play a major role in communication in neutrophil-mediated inflammatory events. Prevention of production of this factor appears to be the major anti-inflammatory action of superoxide dismutase. PMID- 6928667 TI - Membrane-active drugs potentiate the killing of tumor cells by D-glucosamine. AB - D-Glucosamine is toxic to several malignant cell lines and in vivo tumors at concentrations that have little effect upon normal host tissues. Evidence is presented to support the hypothesis that cellular membranes may be the primary targets of glucosamine's tumoricidal activity. Treatment of rat C6 glioma cells with a cytotoxic concentration of glucosamine (20 mM) caused fragmentation of rough endoplasmic reticulum, proliferation of Golgi complexes, evagination of outer nuclear and mitochondrial membranes, and the accumulation of membranous vacuoles and lipid droplets in the cytoplasm. These changes were detected within the first 3 hr after treatment of cultures with glucosamine and became increasingly severe until cell lysis occurred between 24 and 48 hr of treatment. The cytotoxicity of glucosamine was potentiated by the local anesthetic lidocaine, and by other membrane-active drugs, at concentrations that were growth inhibitory but nonlytic. Most of these drugs possessed local anesthetic activity and inhibited glioma sterol synthesis. Within the same period of time required for ultrastructural changes in cellular membranes, glucosamine inhibited the incorporation of [2-(14)C]acetate into sterols and into an unidentified 400 dalton lipid that migrated close to sterols on thin-layer chromatograms. This inhibition was potentiated by lidocaine and increased over the same range of D glucosamine concentrations that led to increased cell toxicity after a 48-hr treatment. These findings suggest that the effects of glucosamine upon cellular membranes may be central to its tumoricidal activity and that glucosamine, in combination with membrane-active drugs, may be useful in the treatment of certain types of tumors, particularly those of the central nervous system. PMID- 6928668 TI - Sensory neurons in culture: changing requirements for survival factors during embryonic development. AB - The effect of nerve growth factor (NGF) and medium conditioned by glioma cells (GCM) on the survival of chicken sensory neurons in culture was investigated. Neurons were isolated from embryos 8 days (E8) to 16 days (E16) old and the proportion of surviving neurons was determined after 2 days in culture. In the absence of NGF or GCM, essentially no neurons survived at any age. In the presence of NGF, survival increased from 25% of the neurons at E8 to 40% between E10 and E12 and then decreased to background level (5%) at E16. In contrast, in the presence of GCM, survival increased continuously from 10% of the neurons at E8 to 75% at E16. At early developmental stages, the effect of NGF and GCM together was greater than the sum of their individual effects: at E8, about 80% of the neurons survived, double the number expected for a simple additive effect. Thus, a significant proportion of chicken neurons from dorsal root ganglia require both NGF and GCM for survival, and this may well include neurons from the ventro-lateral population, which do not respond to NGF alone. As neurons matured, the double requirement progressively decreased and, by E16, NGF no longer increased the number of neurons over that surviving in response to GCM alone. The facts that rat brain extracts mimicked the effect of GCM and that the potency of the brain extracts of rat in the postnatal period increased in parallel with the development of the glial cells suggest that glial cells produce a factor(s) both immunologically and functionally different from NGF which supports the survival of sensory neurons. PMID- 6928670 TI - Large and persistent electrical currents enter the transected lamprey spinal cord. AB - The electrical currents at the surface of the proximal portion of an isolated and transected lamprey spinal cord were measured with an extracellular vibrating probe. Soon after transection, currents of about 0.5 mA/cm2 enter the cut surface of the spinal cord. These currents fall to about a quarter of their initial value within an hour; within the next 2 days they gradually decline from about 100 microA/cm2 to about 4 microA/cm2; they then remain constant up to 6 days posttransection, when the measurements were ended. The pattern of current entry included substantial peaks opposite (and presumably into) the cut ends of giant axons. Response to changes in the ionic composition of the medium indicates that about half of the injury current consists of Na+, and that much of the rest may consist of Ca2+. The measured influx of ions, which adds up to several coulombs per cm2 in a few days, should radically alter the ionic composition of the terminal few millimeters of neural tissue. Thus it may be important in the degenerative and regenerative responses of neurons to axotomy. PMID- 6928669 TI - Development of circadian rhythmicity and light responsiveness in the rat suprachiasmatic nucleus: a study using the 2-deoxy[1-14C]glucose method. AB - The suprachiasmatic nucleus (SCN) of the hypothalamus is thought to play a critical role in circadian rhythm generation and entrainment to the light/dark cycle. In adult rats, the SCN shows a circadian rhythm in metabolic activity level as indicated by 2-deoxy[1-14C]glucose uptake. In the present study, the development of this rhythm was investigated. No diurnal difference in uptake was evident in fetal rats 1--2 days before birth. A significant diurnal difference in SCN 2-deoxyglucose uptake was preseno light at night increased the SCN metabolic levels. According to previous studies, on day 1 the SCN is poorly developed and contains few synapses. At this time the retinohypothalamic tract has not yet developed. We found progressive functional maturation of the SCN through day 21, when the rhythm and light responsiveness resembled those of adult rats. PMID- 6928671 TI - Clumping of acetylcholinesterase activity in the developing striatum of the human fetus and young infant. AB - The distribution of acetylcholinesterase activity (acetylcholine acetylhydrolase, EC 3.1.1.7) in the developing human striatum has been studied histochemically in autopsy material from fetal brains of estimated gestational ages 16-29 weeks (180 1000 g) and from the brains of infants 2 days to 4 months old. The findings provide evidence that striatal acetylcholinesterase activity in the human fetus and neonate is concentrated in a network of densely stained zones that appear in cross section as variably shaped 0.5- to 1.0-mm-wide dark patches distributed in a lighter background matrix. An orderly arrangement of the patches seemed well established in the putamen by the 16th-18th week of gestation (crown-rump length 14-15 cm) but in the caudate nucleus the pattern was still not fully elaborated at these ages. The lateroventral part of the caput was mainly dark and its rostromedial margin, though rich early on in pseudocholinesterase activity, was still without strong acetylcholinesterase activity as late as 20-21 weeks (crown rump length 16-20 cm). The ganglionic eminence at these ages was sharply divided into a dorsal part with little cholinesterase activity and a ventral part with a high content of pseudocholinesterase. Little information was gained about striatal development during late stages of gestation, but in three 5- to 7-month fetal specimens not only dark patches but also patches with dark perimeters and pale centers were present. Clumping of cholinesterase activity appeared at birth and up to the third month of postnatal life. The patches in both caudate nucleus and putamen were dark and of fairly uniform tint in the striatum of the young infant and the matrix staining was darker than in the fetuses. Around the fourth postnatal month hints of the mature pattern were present, with zones of low cholinesterase activity appearing against a dark background in the caudate nucleus and (in one case) a nearly homogeneous staining pattern appearing in the putamen. PMID- 6928673 TI - Phencyclidine interactions with the ionic channel of the acetylcholine receptor and electrogenic membrane. AB - The effects of phencyclidine (PCP) were studied on the electrogenic and chemosensitive properties of the neuromuscular junction of skeletal muscle as well as on the binding sites on the acetylcholine (AcCho) receptor and its ionic channel in the electric organ membranes of the electric ray. The directly elicited muscle twitch was markedly potentiated by prolonging the falling phase of the muscle action potential and blocking delayed rectification. The indirectly elicited muscle twitch was transiently potentiated and then blocked by PCP at concentrations below 60 muM. PCP blocked miniature endplate potentials and AcCho sensitivities at the junctional region of innervated muscle, blocked the extrajunctional sensitivity of the chronically denervated muscle, and significantly depressed the peak amplitude of the endplate current (EPC) in a voltage- and time-dependent manner. PCP also caused acceleration of the time course of EPC decay and shortening of the mean life-time of the open ionic channel. The effects of PCP were not due to inhibition of AcCho receptor sites because PCP did not protect against the quasi-irreversible inhibition of receptor sites by alpha-bungarotoxin, nor did it inhibit binding of [(3)H]AcCho or [(125)I labeled alpha-bungarotoxin to the receptor sites. On the other hand, PCP blocked the binding of [(3)H]perhydrohistrionicotoxin to the sites of the ionic channel of the AcCho receptor. The data suggest that PCP reacts with the electrogenic K(+) channel and the ionic channel associated with the AcCho receptor in the open as well as the closed conformation. PMID- 6928674 TI - In vitro synthesis of the major lens membrane protein. AB - The biosynthetic activity of a polyribosomal fraction isolated from the lens fiber plasma membrane-cytoskeleton complex by DNase I treatment has been assayed. After translation of these polyribosomes in a reticulocyte cell-free system and analysis of the products by electrophoresis in sodium dodecyl sulfate gels, the preferential synthesis of a protein with an apparent molecular weight of 26,000 was observed. By means of immunochemical characterization we showed that this protein, which seems not to be synthesized by "free" polyribosomes, is identical with the major intrinsic plasma membrane protein MP26 of lens fibers. Upon storage, the molecular weight of the newly synthesized protein decreases to about 22,000, a phenomenon that has previously been observed for MP26 in isolated plasma membranes and that may be caused by the presence of a specific proteolytic cleaving site in the protein. PMID- 6928672 TI - Leptinotarsin: a presynaptic neurotoxin that stimulates release of acetylcholine. AB - Leptinotarsin, a toxin found in the hemolymph of the beetle Leptinotarsa haldemani, can stimulate release of acetylcholine from synaptic termini. Leptinotarsin causes an increase in the frequency of miniature end plate potentials (mepps) of the rat phrenic nerve-diaphragm preparation. The increase in the frequency of mepps induced by leptinotarsin is biphasic: about 10% of the total mepps are released in an initial burst that lasts about 90 sec, after which the remaining mepps are released over a period of 10-20 min. Tetrodotoxin has no effect upon the release induced by leptinotarsin, but low-Ca(2+) conditions abolish the first phase. The two phases of release may represent two presynaptic pools of acetylcholine, both of which can be released in quantized form. In a second study, rat brain synaptosomes were incubated with [(3)H]choline and were immobilized on Millipore filters. Leptinotarsin induced release of [(3)H]acetylcholine from this preparation, confirming the release seen by using neurophysiological methods. The ability of leptinotarsin to induce release from either intact nerve terminals or synaptosomes was abolished when the toxin was heated. The releasing activity of leptinotarsin from synaptosomes was also partially dependent upon the presence of Ca(2+) in the perfusing solution. Release from synaptosomes followed first-order kinetics, and was not inhibited by commercial antibodies to black widow spider antigens. The data suggest that leptinotarsin acts as a presynaptic neurotoxin and may be of value as a mechanistic probe in understanding the storage and release of neurotransmitters. PMID- 6928675 TI - Sequence determination of protected oligodeoxyribonucleotides containing phosphotriester linkages by californium-252 plasma desorption mass spectrometry. AB - A mass spectrometric method for determining the sequence and molecular weight of protected oligodeoxyribonucleotides is described. By using the method of 252Cf plasma desorption mass spectrometry [Macfarlane, R. D. & Torgerson, D. F. (1976) Science 191, 920--925], positive-ion mass spectra were obtained for a series of protected oligonucleotides extending to a decanucleotide; the spectra were dominated by the presence of the oligonucleotide molecular ion. The negative-ion mass spectra were characterized by a nested set of fragment ions extending from the 3'- or 5'-terminal nucleotide to the opposite terminal nucleotide, thereby identifying the sequence. The utility of this method has been demonstrated by the sequence determination of protected tetra-, penta-, and hexanucleotides synthesized by the improved phosphotriester method. PMID- 6928676 TI - Corrected splicing of a chicken ovalbumin gene transcript in mouse L cells. AB - Mouse thymidine-kinase-negative L cells were transformed with a cloned chicken ovalbumin gene linked to the cloned thymidine kinase gene from herpes simplex virus type 1. Most thymidine-kinase-positive clones contained one or more copies of the ovalbumin gene, which were stably maintained for at least 6 months during continuous culture under selective conditions. Transcription of the ovalbumin gene was detected at a low level, producing RNA molecules that were correctly spliced and polyadenylylated by comparison with genuine ovalbumin mRNA. However, the 5' end of these RNA molecules does not correspond to that of ovalbumin mRNA. PMID- 6928677 TI - Cloning of sea urchin actin gene sequences for use in studying the regulation of actin gene transcription. AB - In order to investigate the regulation of actin gene transcription during early sea urchin development, a specific hybridization probe for actin sequences is required. Such a probe was produced by cloning cDNA transcribed from a sea urchin poly(A)-containing mRNA preparation enriched for actin message. Double-stranded DNA was ligated into the BamHI restriction site of plasmid pBR322, and the resulting hybrid molecules were used to transform the Escherichia coli strain ML100. After preliminary screening of bacterial colonies by antibiotic sensitivity and hybridization back to the original cDNA, clones containing sea urchin DNA were further characterized by a positive translation assay in which total sea urchin mRNA was hybridized to plasmid, and the hybridized message then was eluted and translated in a reticulocyte cell-free protein-synthesizing system. In this way, one clone (pSA38) was found to hybridize selectively to sea urchin mRNA coding for a protein of 43,000 daltons. This protein was identified as actin by three criteria: electrophoretic migration in two-dimensional polyacrylamide gels, affinity for DNase I, and peptide mapping. Restriction endonuclease and heteroduplex mapping of pSA38 indicate that it contains a 1.5 kilobase-pair insert and is therefore likely to contain a large portion of the actin coding sequence. By using pSA38 as a hybridization probe, it has been found that the level of actin-specific RNA sequences increases dramatically during early sea urchin development. PMID- 6928680 TI - Protein phosphorylation and sodium conductance in nerve membrane. AB - High molecular weight proteins extracted from the walking nerves of the shore crab (Carcinus maenas) exhibit a cycle of phosphorylation-dephosphorylation that is influenced by neurotropic compounds and inorganic ions. The net phosphorylation state of the proteins is increased in the presence of K+ ions and decreased with Na+ ions. In the absence of Mg2+ there is no phosphorylation. Ca2+ ions at low concentrations are necessary for optimal phosphorylation. At high concentration (above 0.1 mM), Ca2+ ions are inhibitory. Neurotropic compounds generally inhibit the phosphorylation process. More specifically, tetrodotoxin and veratridine, depending on the ionic composition of the medium, have opposite effects on the phosphorylation process, a result in agreement with their known physiological action. It is suggested that the high molecular weight components thus identified are part of the sodium permeation sites and that the conductance state of those sites is controlled by a phosphorylation process. PMID- 6928678 TI - Evidence for involvement of proline cis-trans isomerization in the slow unfolding reaction of RNase A. AB - The three exposed tyrosines of RNase A have been converted to nitrotyrosines by reaction with tetranitromethane, and the changes in the ionization properties of these nitrotyrosines have been used to follow the kinetics of unfolding of the nitrated protein. It is found that the nitrotyrosines not only are sensitive to the overall disruption of the protein structure, which occurs in a faster reaction, but also serve as reporter groups for the slower reaction which takes place in the unfolded state. This slower reaction corresponds to the formation of the slow-refolding species of the unfolded protein. The kinetic properties of the slower reaction--guanidine-dependence of the rate and activation ethalpy--are similar to those of the proline cis-trans isomerization in a model peptide determined in the same conditions. It is concluded that proline cis-trans isomerization is indeed the rate-limiting factor for the formation of the slow refolding species. Because the influence of proline cis-trans isomerization on the properties of the nitrotyrosines in the unfolded protein is probably due to a local effect, it is suggested that most of the optical changes observed during this slow unfolding reaction arise from the effect of the cis-trans isomerization of the Asn113-Pro114 bond on the properties of nitrotyrosine 115. PMID- 6928679 TI - Properties of an acid phosphatase in pulmonary surfactant. AB - Lung surfactant, a lipid-protein complex purified from dog lungs, contains a highly active phosphomonoesterase associated with it. This phosphatase is quite specific for the hydrolysis of phosphatidic acid and 1-acyl-2-lysophosphatidic acid. The enzyme possesses many of the characteristics of the microsomal enzyme, phosphatidate phosphohydrolase (EC 3.1.3.4). In addition, we have shown that this enzyme will also convert phosphatidylglycerol phosphate [1-(3-sn-phosphatidyl)-sn glycerol-1-P] to phosphatidylglycerol [1-(3-sn-phosphatidyl)-sn-glycerol] and Pi. The phosphatidylglycerol phosphate was made available to the surfactant enzyme in a coupled assay by hydrolysis of cardiolipin [1-(3-sn-phosphatidyl)-3-(3-sn phosphatidyl)-sn-glycerol] by stereospecific cleavage with phospholipase C (phosphatidylcholine cholinephosphohydrolase, EC 3.1.4.3) from Bacillus cereus. This enzyme has been previously shown to generate the naturally occurring isomer of phosphatidylglycerol phosphate because it has specificity for the 3-(3-sn phosphatidyl) group of cardiolipin. Other properties of the surfactant enzyme are discussed in relation to its presence in lung surface active material. PMID- 6928681 TI - Presence of cobalamin analogues in animal tissues. AB - Cobalamin (Cbl, vitamin B-12) has been extracted and isolated from a number of animal tissues by using (i) reverse-affinity chromatography on R protein Sepharose followed by adsorption to and elution from charcoal-coated agarose and (ii) paper chromatography. Radioisotope dilution assays showed that only 75-97% of the Cbl chromatographed in the position of crystalline Cbl. The remaining 3 25% was present in a number of slower and faster moving fractions. This suggested that Cbl analogues are present in animal tissues because appropriate controls ruled out the possibility that this material was artifactually derived from Cbl during the extraction and purification procedures. With a large-scale isolation from rabbit kidney, the material in five such fractions contained cobalt and had absorption spectra that were similar to but different from the spectrum of Cbl, indicating that they were Cbl analogues. Compared to Cbl, these Cbl analogues had decreased but definite affinities for Cbl-binding proteins with the following order of strength of binding: R protein > transcobalamin II > intrinsic factor. Compared to Cbl, they also had decreased but definite growth-promoting activity for two microorganisms, Euglena gracilis and Lactobacillus leichmannii, which require Cbl for growth. These Cbl analogues differed from each other and from 18 synthetic Cbl analogues, including the most common Cbl analogues synthesized by microorganisms, in at least one of the above features. These studies indicate that animal tissues contain a number of Cbl analogues whose origins, structures, and biologic activities remain to be determined. PMID- 6928682 TI - Mechanisms of membrane assembly: effects of energy poisons on the conversion of soluble M13 coliphage procoat to membrane-bound coat protein. AB - The coat protein (gene 8 product) of coliphage M13 spans the host cell plasma membrane prior to its assembly into extruding virions. It is made as a soluble precursor, termed procoat, with an extra 23 NH2-terminal amino acid residues. We have examined the effect of metabolic poisons on the assembly of procoat into the plasma membrane and its proteolytic conversion to coat protein. Protein synthesis and proline uptake were measured to assess the effect of each poison on cellular high-energy phosphate and on the transmembrane protonmotive force, respectively. Arsenate, which abolished protein synthesis but did not affect proline uptake, had no measurable effect on the conversion of procoat to coat protein. In contrast, the uncoupler carbonylcyanide m-chlorophenylhydrazone (CCCP) blocked conversion of procoat to coat protein. Neither CCCP nor arsenate inhibited the ability of a detergent-solubilized and highly purified preparation of leader peptidase to convert procoat to coat protein in the presence of detergents. The procoat that accumulated in the presence of CCCP was membrane bound. A spontaneous mutant that grows in the presence of CCCP showed (i) CCCP-resistant proline uptake in whole cells, (ii) CCCP-resistant uptake in inner membrane vesicles, and (iii) CCCP-resistant conversion of procoat protein to coat protein. These data suggest that an electrochemical gradient is at least indirectly necessary for the proper assembly of procoat into the cellular membrane. PMID- 6928683 TI - Characterization of double-stranded-RNA-activated kinase that phosphorylates alpha subunit of eukaryotic initiation factor 2 (eIF-2 alpha) in reticulocyte lysates. AB - Incubation of reticulocyte lysates with low levels of double-stranded (ds) RNA (1 20 ng/ml) activates a cAMP-independent protein kinase (dsI) that phosphorylates the alpha-subunit (M(r) 38,000) of initiation factor 2 (eIF-2) and produces an inhibition of protein chain initiation similar to that caused by heme deficiency. Activation of dsI from its latent precursor takes place on the ribosomes and requires ATP. dsI can also be activated in ribosomal salt washes and in partially purified preparations of the latent precursor of dsI. In all preparations, activation is accompanied by the ds RNA-dependent phosphorylation of a polypeptide doublet that migrates as bands of 67 and 68.5 kilodaltons (67/68.5) in NaDodSO(4)/acrylamide gels. The rate of phosphorylation of these components in a ribosome salt wash is more rapid than the ds RNA-dependent phosphorylation of eIF-2alpha. Other polypeptides in the salt wash also undergo ds RNA-dependent phosphorylation, but their significance is not clear. All of these phosphorylations are prevented by high concentrations of poly(I).poly(C)(20 mug/ml), but not by an antiserum specific for the heme-regulated eIF-2alpha kinase. Both the latent and activated forms of dsI have been partially purified from a 0.5 M KCl wash of reticulocyte ribosomes. The two species have similar M(r)s ( approximately 120,000) and sedimentation coefficients ( approximately 3.75 S), which suggests that activation of dsI probably does not involve extensive changes. By comparison, the heme-regulated eIF-2alpha kinase has an M(r) of approximately 160,000 and sediments at approximately 6.6 S. However, in vitro, dsI and HRI both phosphorylate the same site(s) of eIF-2alpha. Purified dsI inhibits protein synthesis in hemin-supplemented lysates with the same kinetics induced by the addition of ds RNA; both inhibitions are reversed by eIF 2. dsI that has been activated in the salt wash and then purified does not require ds RNA for expression and no longer displays phosphorylation of the 68.5/67 doublet, which appears to occur only during activation. The data support the view that this component(s) may be the eIF-2alpha kinase activated by ds RNA. PMID- 6928684 TI - Molecular mechanism of acetylcholine receptor-controlled ion translocation across cell membranes. AB - Two molecular processes, the binding of acetylcholine to the membrane-bound acetylcholine receptor protein and the receptor-controlled flux rates of specific inorganic ions, are essential in determining the electrical membrane potential of nerve and muscle cells. The measurements reported establish the relationship between the two processes: the acetylcholine receptor-controlled transmembrane ion flux of (86)Rb(+) and the concentration of carbamoylcholine, a stable analog of acetylcholine. A 200-fold concentration range of carbamoylcholine was used. The flux was measured in the millisecond-to-minute time region by using a quench flow technique with membrane vesicles prepared from the electric organ of Electrophorus electricus in eel Ringer's solution at pH 7.0 and 1 degrees C. The technique makes possible the study of the transmembrane transport of specific ions, with variable known internal and external ion concentrations, in a system in which a determinable number of receptors is exposed to a known concentration of ligand. The response curve of ion flux to ligand was sigmoidal with an average maximum rate of 84 sec(-1). Carbamoylcholine induced inactivation of the receptor with a maximum rate of 2.7 sec(-1) and a different ligand dependence so that it was fast relative to ion flux at low ligand concentration but slow relative to ion flux at high ligand concentration. The simplest model that fits the data consists of receptor in the active and inactive states in ligand-controlled equilibria. Receptor inactivation occurs with one or two ligand molecules bound. For channel opening, two ligand molecules bound to the active state are required, and cooperativity results from the channel opening process itself. With carbamoylcholine, apparently, the equilibrium position for the channel opening step is only one-fourth open. The integrated rate equation, based on the model, predicts the time dependence of receptor-controlled ion flux over the concentration range of carbamoylcholine investigated. The values of the constants in the rate equation form the basis for predicting receptor-controlled changes in the transmembrane potential of cells and the conditions leading to transmission of signals between cells. PMID- 6928685 TI - Mutants altering coordinate synthesis of specific myosins during nematode muscle development. AB - Mutations in the unc-52 gene on linkage group II retard the construction of body wall muscle sarcomeres during larval development in the nematode Caenorhabditis elegans. Unc-52 mutants show decreased accumulation of myosin heavy chains relative to other polypeptides during larval development, correlating with the structural retardation. Pulse radiolabeling experiments show that decreased synthesis of specific body-wall myosin heavy chains that are encoded by the unc 54 gene on linkage group I is responsible for the defective myosin accumulation. In the wild type, a constant ratio of the synthesis of the unc-54-coded myosin B to myosin A, about 2:1, is maintained during the larval stages in which the synthesis of both myosins increases exponentially and rapid sarcomere growth and addition ensues. During the first 26 hr of larval development, before any structural or behavioral effects of unc-52 mutations are apparent, the synthesis of myosin heavy chains is also normal. By 38 hr, decreased synthesis of myosin B is detected in the unc-52 mutant SU200, when sarcomere growth slows considerably. The effects of mutation in the unc-52 locus are trans acting upon the synthesis of unc-54-coded myosin in a specific set of muscle cells during a defined period of larval development. PMID- 6928687 TI - Camphorquinone-10-sulfonic acid and derivatives: convenient reagents for reversible modification of arginine residues. AB - Camphorquinone-10-sulfonic acid hydrate was prepared by the action of selenous acid on camphor-10-sulfonic acid. Camphorquinone-10-sulfonylnorleucine was prepared either from the sulfonic acid via the sulfonyl chloride or by selenous acid oxidation of camphor-10-sulfonylnorleucine. These reagents are useful for specific, reversible modification of the guanidino groups of arginine residues. Camphorquinonesulfonic acid is a crystalline water-soluble reagent that is especially suitable for use with small arginine-containing molecules, because the sulfonic acid group of the reagent is a convenient handle for analytical and preparative separation of products. Camphorquinonesulfonylnorleucine is more useful for work with large polypeptides and proteins, because hydrolysates of modified proteins may be analyzed for norleucine to determine the extent of arginine modification. The adducts of the camphorquinone derivatives with the guanidino group are stable to 0.5 M hydroxylamine solutions at pH 7, the recommended conditions for cleavage of the corresponding cyclohexanedione adducts. At pH 8-9 the adducts of the camphorquinone derivatives with the guanidino group are cleaved by o-phenylenediamine. The modification and regeneration of arginine, of the dipeptide arginylaspartic acid, of ribonuclease S-peptide, and of soybean trypsin inhibitor are presented as demonstrations of the use of the reagents. The use of camphorquinonesulfonyl chloride to prepare polymers containing arginine-specific ligands is discussed. PMID- 6928689 TI - Fluorescence energy transfer studies on the active site of papain. AB - Measurements have been performed of the excited-state lifetimes and fluorescence yields of papain tryptophan units when acyl derivatives of Phe-glycinal are bound at the active site of the enzyme. The enhancement of tryptophan fluorescence in complexes of papain with the acetyl or benzyloxycarbonyl derivatives is not stereospecific with respect to the configuration of the phenylalanyl residue, and the L and D isomers are equally effective as active-site-directed inhibitors of papain action. Evidence is offered in favor of the conclusion that this enhancement is primarily a consequence of the interaction of the phenylalanyl side chain of the inhibitor with Trp-69 of the enzyme. This residue can exchange fluorescence energy with the other four tryptophans of papain (Trp-7, Trp-26, Trp 177, Trp-181) upon excitation near their absorption maxima, but such "homotransfer" is absent if they are excited at the long-wave edge of their absorption spectra. Crystallographic data indicate that Trp-26 is most favorably positioned for efficient energy exchange with Trp-69, and the fluorescence data have been used to calculate a distance of 11 A between the two residues; this value is in satisfactory agreement with that found by crystallography. When derivatives of Phe-glycinal bearing an amino-terminal mansyl [6-(N-methylanilino) 2-naphthalene sulfonyl] group are bound at the active site of papain, the tryptophan fluorescence is quenched, as compared with that of the complex of papain with acetyl-Phe-glycinal, indicating energy transfer from papain tryptophan (most probably via Trp-26) to the fluorescent probe group. Although the L and D isomers of mansyl-Phe-glycinal are equally effective as inhibitors of papain action, the fluorescence quenching by the two isomers is different. PMID- 6928688 TI - Vero cells injected with adenovirus type 2 mRNA produce authentic viral polypeptide patterns: early mRNA promotes growth of adenovirus-associated virus. AB - Adenovirus type 2 mRNAs were injected via glass capillaries into Vero cells, a line of African green monkey kidney cells permissive for adenovirus growth. Polypeptides synthesized after injection were labeled with 35S-labeled amino acids, precipitated with antiviral sera, and analyzed by polyacrylamide gel electrophoresis. Both early and late viral mRNAs give rise to authentic polypeptides. The in vivo translation of mRNAs can be measured as late as 24 hr after injection. The ability to analyze the protein products of microinjected mRNAs directly should greatly extend the applications of the procedure. Vero cells injected with early mRNA from adenovirus type 2 support the growth of adenovirus-associated virus, a defective virus that is dependent on adenovirus helper functions. This result demonstrates that a measurable biological activity, the ability to overcome the defectiveness of adenovirus-associated virus, resides in early adenovirus mRNA. PMID- 6928691 TI - Spectroscopic studies of the protein-methylglyoxal adduct. AB - Spectroscopic measurements are reported for the effects of pH, time, solvent, and chemical modification of arginine and lysine side chains on the reaction of proteins with methylglyoxal. The reaction responsible for the appearance of a brown coloration and increased submolecular electronic activity in the proteins involves the epsilon-amino groups of the lysine residues. It is concluded that the primary step in the reaction involves the formation of a Schiff base linkage between the lysine side chain and methylglyoxal. These findings reaffirm the concept that, by the formation of Schiff bases, aldehydes can act as electron acceptors in charge transfer interactions with proteins. PMID- 6928686 TI - Reversible dissociation of linker histone from chromatin with preservation of internucleosomal repeat. AB - Procedures are described for the dissociation of histones H1 and H5 from chicken reticulocyte chromatin without disruption of the native core histone-DNA complex. The comparative properties of native and depleted chromatin with respect to sedimentation, thermal denaturation, and sensitivity to nuclease digestion have been studied. The changes in these properties resulting from removal of the linker histones are fully reversed when histone H5 is added back to the depleted chromatin. PMID- 6928690 TI - Electron microscope study of the kinetics of the fiber-to-crystal transition of sickle cell hemoglobin. AB - The intermediates and the rate-limiting step in the crystallization of deoxygenated sickle hemoglobin have been determined by a kinetic study with the use of electron microscopy. In slowly stirred solutions of deoxygenated hemoglobin S [Pumphrey, J. & Steinhardt, J. (1977) J. Mol. Biol. 112, 359--375], the sequential appearance of fibers have a diameter of approximately equal to 210 A, bundles of aligned fibers in well-ordered arrays, "thick" fibers of approximately equal to 470 A diameter, and microcrystals is observed. Only the fibers having a diameter of approximately equal to 210 A and bundles of aligned fibers are assigned as kinetically important intermediates of the fiber-to crystal transition. Addition of microscopic seed crystals obtained from slowly stirred solutions of deoxyhemoglobin S to a solution composed of only fibers and hemoglobin monomers results in more rapid crystallization than in control solutions. Addition of seed crystals after the formation of bindles of aligned fibers does not alter the overall kinetics of crystallization. The results demonstrate that alignment of fibers is the rate-limiting step in the crystallization process and results in formation of nucleation sites for crystal growth. PMID- 6928692 TI - Structural details of membrane-bound acetylcholine receptor from Tropedo marmorata. AB - A projection, at 15- to 20-A resolution, is presented of the structure of the membrane-bound acetylcholine receptor protein from Torpedo marmorata. The projection has its axis perpendicular to the membrane plane; its main contribution originates from a hydrated portion of the protein, which extends from the membrane into the aqueous medium. The structure is distinctly asymmetric, with individual morphological subunits barely resolvable. These results have been obtained by noncrystallographic averaging, using correlation functions, applied to electron micrographs of receptor-rich membrane fragments. The micrographs had been taken with minimal beam exposure in a scanning transmission electron microscope. PMID- 6928694 TI - Independent lines of evidence suggesting a major gap junctional protein with a molecular weight of 26,000. AB - Several polypeptides have been described in the past as components of gap junction fractions. Of these, a peptide of Mr 26,000 is found in gap junctions isolated from livers of different species under conditions that minimize proteolysis. Tryptic digestion of purified "intact" junctions causes the rapid disappearance of this peptide with a concomitant appearance of a band of Mr 10,000, which has previously been found to be characteristic of junctional fractions isolated with the aid of proteolytic treatment. Both the peptides of Mr 26,000 and 10,000 are missing from gap junction preparations after partial hepatectomy, when gap junctions are absent from the surface of the hepatocytes. They have reappeared in fractions from the livers of animals killed 3 days postoperatively, when gap junctions are again present in vivo. PMID- 6928695 TI - Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz 2-oxa-1,3-diazole-phallacidin. AB - An active fluorescent derivative of the actin-binding mushroom toxin phallacidin has been synthesized. Convenient methods were developed to stain actin cytoskeletal structures in living and fixed cultured animal cells and actively streaming algal cells. Actin binding specificity was demonstrated by competitive binding experiments and comparative staining of well-known structures. Large populations of living animal cells in culture were readily stained by using a relatively mild lysolecithin permeabilization procedure facilitated by the small molecular size of the label. Actin in animal cells was stained stress fibers, ruffles, the cellular geodome, and in diffuse appearing distributions apparently associated with the plasma membrane. Staining of actin cables in algae with nitrobenzoxadiazole (NBD)-phallacidin did not inhibit cytoplasmic streaming. NBD phallacidin provides a convenient actin-specific fluorescent label for cellular cytoskeletal structures with promise for use in studies of actin dynamics in living systems. PMID- 6928693 TI - Construction of recombinant plasmids containing rat muscle actin and myosin light chain DNA sequences. AB - The construction and partial characterization of recombinant bacterial plasmids carrying DNA sequences that hybridize with rat skeletal muscle actin and a myosin light chain mRNA is described. DNA of one clone hybridizes specifically with the muscle-specific alpha-actin mRNA. Three plasmid clones contain DNA inserts that hybridize with muscle as well as with nonmuscle actin mRNA. A fifth plasmid contains sequences complementary to mRNA coding for myosin light chain 2. DNA of this plasmid hybridizes specifically with RNA extracted from muscle and differentiated muscle cultures but not with RNA extracted from proliferating mononucleated myogenic cells. PMID- 6928696 TI - [Changes in glutathione reductase activity in different rat tissues after the administration of radioprotective agents]. PMID- 6928697 TI - Analysis of serial radionuclide bone images in osteosarcoma and breast carcinoma. AB - The authors first describe and illustrate didactically the use of the Kaplan Meier actuarial technique for serial diagnostic studies. They then present an analysis of previously published data on the results of serial radionuclide bone images in patients with osteosarcoma or breast carcinoma, using this technique. The data indicate that patients with osteosarcoma show an almost linear increase in the occurrence of bone metastases between 5 and 29 months after diagnosis; the rate is approximately 1% per month. Patients with breast cancer, on the other hand, show a biphasic rate of development, averaging only 0.5% per month during the first year after diagnosis but increasing rapidly to approximately 2% per month after 15 months. PMID- 6928700 TI - [Christian]. PMID- 6928698 TI - Changing indications for bone scintigraphy in patients with osteosarcoma. AB - Fifty-six patients with osteosarcoma were studied to determine the onset of pulmonary and bone metastases. While pulmonary metastases were always detected prior to bone metastases in the era before adjuvant chemotherapy, in this study of patients on adjuvant therapy 16% of patients with metastases showed osseous metastases prior to or without pulmonary metastases. PMID- 6928699 TI - [Treatment of acute lymphoblastic leukemia]. PMID- 6928701 TI - Legally speaking. The MD-patient relationship: still sacred. PMID- 6928702 TI - [Treatment of large mandibular cysts (author's transl)]. AB - Apart from certain particular types of lesions, the diagnosis of a histologically benign "large mandibular cyst" (paradental cyst, epidermal cyst, ameloblastoma...) should lead to an attempt at conservative treatment: this does not alter mandibular continuity and if possible, the inferior dental neurovascular pedicle, the soft tissues of the buccal lining, and the dental organs. It is finally the gross pathological findings and if necessary the results of an extemporaneous histological examination that will supply the information leading to the choice of the best type of treatment: marsupialization, enucleation, curettage, "pressure curettage", uninterrupting resection. This attitude requires prolonged postoperative radiological supervision and does not exclude the need for an interrupting resection in unfavourable cases at a later date. PMID- 6928703 TI - [Treatment of voluminous keratocysts of the maxilla (author's transl)]. AB - Recurrences of keratocysts are infrequently reported. Excision of these cysts should therefore always be conservative in nature, preferably by interrupting resection. Bimaxillary blocking is not essential, even in the most voluminous cysts. PMID- 6928704 TI - [Conservative surgical treatment for keratocysts of basal cell naevomatosis. Some results (author's transl)]. AB - Excision of keratocysts of basal cell nevomatosis using the principle of conservative surgical treatment of maxillary cysts is usually followed by good secondary bone reconstruction without recurrence. Certain precautions are however necessary, the most important being the resection of the parts of the gums adherent to the cyst wall (where perhaps the cyst developed and where recurrences are most likely to occur). Any tooth germ which may be attached to the cyst must also be removed. Postoperative follow-up must include supervision of the bone reconstruction and tooth germ which have not yet developed (even in the absence of an image of a cyst) until the end of adolescence. In adult age, however, there is very little risk of new keratocysts cysts developing. PMID- 6928705 TI - [Osteochondroma of the head of the mandibular condyle in a 68-year-old woman (author's transl)]. AB - The interest of this case lies in the fact that an osteochondroma of the head of the mandibular condyle is rarely seen, its appearance in a women aged 68 years (it is usually noted in young subjects), and the good results after surgery (controlled by radiological examination two years later). PMID- 6928706 TI - [Conservative surgical treatment for large maxillary cysts. Some comments on technique (author's transl)]. AB - Conservative surgical treatment for large maxillary cysts consists of releasing the cystic wall of the bony cavity without destroying the pulp of the teeth which have apices close to the operated cavity (unless the tooth is already dead). The vestibular approach is through one or two orifices and is as small in size as possible. This technique generally allows conservation of the vitality of the largest number of teeth and avoids postoperative collapse. PMID- 6928707 TI - [Effects of trauma to the facial bones on the anterior shelf of the base of the skull (author's transl)]. AB - The different types of fractures of the upper jaw and facial bones and their extension to the anterior wall of the frontal sinus are discussed. Possible effects on the bony floor of the anterior shelf of the base of the skull and subjacent meninges are outlined. These injuries are then reviewed as part of the larger picture of lesions of the middle third of the craniofacial region. Several types can be distinguished:I.--Lesions in the anterior wall of the frontal sinus only, II.--Lesions affecting the base of the facial bones, III.--Lesions in the frontal vault radiating to the base, IV.--Direct lesions of the middle third, V.- Isolated lesions from back-lash or distortion, VI.--External fronto-orbital impactions. Only types 2, 3, 4, and 5 affect the middle third of the endocranial region. As far as the risk of fistula formation is concerned, facial lesions (type 2) have a good prognosis, while frontal lesions (type 3, 4, and 5) have a poor prognosis. This criterium can assist in making decisions, after superficial examination of the lesions, whether to employ major surgery or not in a deep, difficult region. PMID- 6928708 TI - [Treatment of craniofaciostenosis (author's transl)]. AB - The authors suggest a one-stage treatment for craniofaciostenosis, using two surgical teams, to try to correct both the functional problems and morphological disorders. PMID- 6928709 TI - [Nasal glioma (author's transl)]. AB - Rare tumors are sometimes encountered in maxillofacial surgical practice and the operative approach, external, intranasal, or endocranial, may be difficult to choose. Preliminary angiography and particularly computer tomography can be of invaluable assistance in making the decision, especially in cases of nasofrontal glioma with heterotopic localization of glial tissue but without brain connections. PMID- 6928711 TI - ["Pseudo-carcinomatous hyperplasia" of the epithelial rests of Malassez (author's transl)]. AB - A case of mandibular osteitis is reported, showing histologically, an important pseudo peitheliomatous hyperplasia. A possible histological explanation of this observation is that the inflammatory process may be responsible for an odontogenic cell rest (of Malassez) hyperplasia derived from the dental lamina. PMID- 6928710 TI - [A case of intra- and extracranial development of a craniofacial teratoma. Excision during the neonatal period through a mixed cranio-facial approach (author's transl)]. AB - A newborn infant was found to have a laterocervical swelling invading the floor of the mouth. Exploration of the mass revealed that there was invasion of the left side of the soft palate and, more particularly, a prominence in the temporal fossa causing an obvious cranio-facial asymmetry. Radiological and neuroradiological investigations demonstrated the presence of a tumor destroying the greater wing of the sphenoid, invading the left side of the temporal fossa, extending into the pterygomaxillary fossa up to the soft palate, and finally appearing exteriorly in the sub-maxillary region. Excision was carried out in the neonatal period because of the poor tolerance from the neurological point of view. A wide cranio-facial approach was first employed, enabling resection of the point of the temporal lobe, clogging of the cranial base, and excision as one piece of the complete palatocervical extension of the tumor. Follow-up one year later showed that the child possessed excellent neurological development and there was no sign of recurrence of the mass. A review of the published literature showed the extremely rare nature of this type of localization of cervicofacial teratomas (5 other cases have been reported). The surgical procedures and the problems encountered are discussed as well as the indications for excision, based on results obtained in this case and those previously reported. The etiology and anatomy are also reviewed in order to establish their true significance in the case of congenital cranio-facial tumors. PMID- 6928712 TI - [Diagnostic and therapeutic problems occasioned by a voluminous cervical schwannoma (author's transl)]. AB - A tumour of the nervous sheath, the schwannoma often entails difficult diagnostic problems linked to its anatomopathological polymorphism. A medical case of a benign schwannoma of the neck has been reported. In this case, it concerns a tumour moreworthy for its size, its adherence, elements which are unusual in a regular tumour which is well inserted in a capsule, and which has entailed difficult therapeutic problems. Its atypical histological shape brought up a debate between its diagnostic on the one of a fibro-myxoma. PMID- 6928714 TI - [Closure of oroantral communication of dental origine, using Celesnik's technique]. PMID- 6928715 TI - [Surgical treatment of basal-cell epitheliomas of the scalp and ear (author's transl)]. AB - Basal-cell epitheliomas of the scalp are frequently observed on pre-existing chronic lesions: radiodermatitis or Jadassohn's sebaceous naevus. In cases where no irradiation has been given, basal-cell epitheliomas of the scalp should be treated by simple surgical excision. When irradiation has been applied, deep invasion must be recognized as an insufficient excision can often be fatal. PMID- 6928713 TI - [Atypical meningocele localization in the new-born. A report on one case (author's transl)]. AB - A case is reported of a new-born infant presenting with a voluminous laterofacial tumor which had literally blown up the right side of the face. The tumor was found to be a meningocele. Treatment was applied in such a way as to cause the least surgical trauma possible and to use the natural flexibility of the tissues in an infant of this age. The rare nature of this localization is emphasized. PMID- 6928717 TI - [Recurrent basal cell epitheliomas and those developing on pre-existing lesions (author's transl)]. AB - Cancerous changes occur most frequently in four types of chronic acquired lesions: rare lupus scars and those of long-standing burns, rhinophymas, and radiodermatitis. Insufficient therapy is often applied because of underestimation of potential changes, fear of hemorrhage, or lack of knowledge of the extent of the lesion. The ulcerous forms and those developing in scar tissue have the poorest prognosis, and this also applies to centrofacial basal cell epitheliomas. Recurrences after radiotherapy are of bad omen, and they must be treated by wide surgical excision. PMID- 6928716 TI - [Rapidly progressing basal-cell naevi (author's transl)]. AB - Basal-cell epitheliomas are of primary importance when discussing a case of multiple naevi. Two factors have to be considered to explain therapeutic failures: --Firstly, the very active local malignancy of these basal-cell epitheliomas; --Secondly, the long delay in applying drastic treatment such as wide excision and immediate repair, and the danger arising from divergent therapy because of lack of a common decision between the various specialists concerned: dermatologist, ophthalmologist, radiotherapist, and plastic or maxillofacial surgeon. PMID- 6928718 TI - [Radiotherapy of basal cell epitheliomas of the face (author's transl)]. AB - Great advances have been made in the techniques used for radiotherapy, both in safety measures to avoid accidents due to dosage errors, and by the use of new rays such as electrons from accelerators which permit more selective irradiation avoiding surrounding tissues. The authors discuss the indications for the different radiotherapy methods used in basal cell epitheliomas of the face, when compared with or used in association with other procedures such as operative therapy, in relation to the characteristics of the tumor, its proximity to delicate organs, the age of the patient. The possible esthetic and functional sequelae, and the cost to society. PMID- 6928720 TI - [Irradiation of basal cell epitheliomas of the face: a handicap for the surgeon in some cases of recurrence (author's transl)]. AB - A case is reported which illustrates the progressive relapsing nature and local invasive character of certain irradiated basal cell epitheliomas. One such case, that involved the tragus initially, and had been irradiated on five occasions, successively invaded the lobe of the ear, the auditory canal, the helix, the mastoid, and the zygomatotemporal region in spite of six operations and the use of cryotherapy. PMID- 6928724 TI - [Basal cell epitheliomas of the face. General treatment principles (author's transl)]. AB - The author describes the advantages and disadvantages of the three possible types of treatment for basal cell epitheliomas: --Dermatological which combines all the physical methods for destroying the tumor. --Surgical involving wide excision and wound repair. --Radiotherapeutic by the application of radium curietherapy or iridium wires. PMID- 6928721 TI - [Topical meeting of the Society of Dentistry and Maxillofacial Surgery, 16 June 1979. Basocell epitheliomas of the face]. PMID- 6928722 TI - [Clinical diagnosis of basal cell epitheliomas of the face (author's transl)]. AB - Basal cell epitheliomas occur most frequently on the face and have very variable appearances: cicatricial and flat, ulcerous, even deep, and nodular, sclerodermiform, or pigmented. A very positive diagnostic finding is small epitheliomatous pearls often grouped together at the periphery of the lesion. Though the effects of these lesions are purely local, as metastases never occur, they frequently have a tendency to relapse. PMID- 6928719 TI - [Endocurietherapy of basal-cell epitheliomas of the face (author's transl)]. AB - The diagnosis of basal cell epitheliomas of the face is usually made at an early stage (lesions of less than one centimetre in diameter) in France. Because of their good prognosis, without metastatic risk (95% recovery rate), therapy can be chosen as a function of its cost and the esthetic result obtained. The author considers that surgery, endocurietherapy with iridium, and plesioradiotherapy are equally effective but should be chosen according to the extent and location of the lesion. The ear, and to a lesser degree the nose, are the major indications for curietherapy. For the cyclids and flat surfaces (temporal or frontal regions etc...) surgery, and plesioradiotherapy are the treatment of choice. PMID- 6928723 TI - [The histopathology of basal cell carcinomas (author's transl)]. AB - The authors review the different histological forms of basal cell carcinoma, paying particular attention to early forms, sometimes apparently harmless. They stress the diffusing nature of sclerodermiform carcinoma which is often more widespread than clinical appearances suggest. They indicate the current prevalence of basal cell carcinomas in the young individual aged less than 30 years, apparently the consequence of excessive exposure to sunlight. Finally, they give a number of technical indications which are useful in ensuring better orientation and more complete study of the operative specimen, if a frozen section has not been possible, since for this tumour, purely locally malignant, complete excision from the outset offers the best guarantee of cure. PMID- 6928725 TI - [Extension of basal cell epitheliomas. Value of extemporaneous histological examination and bone scintigraphy (author's transl)]. AB - Though basal cell epitheliomas present the advantage of lack of spread into lymph nodes and of having only local activity they can extend considerably both on the surface and in the deep tissues. Because of the difficulty in obtaining complete excision of recurrences the authors are prudent in their attitude and take all possible precautions during treatment of these lesions, including extemporaneous histological examinations and bone scintigraphy which appear to be indispensable. PMID- 6928726 TI - [Basal cell epitheliomas of the labial region (author's transl)]. AB - Treatment of basal cell epitheliomas of the labial region is essentially surgical excision. Curietherapy appears to be indicated for sclerodermiform epitheliomas, extensive lesions, and when surgery is contra-indicated. PMID- 6928727 TI - Case report 111. PMID- 6928728 TI - Chronic myelogenous leukemia: a 22-year survival. AB - A 25-year-old woman presented with classic features of chronic myelogenous leukemia. After 15 months of control with splenic irradiation, rising blood counts necessitated busulfan therapy, producing severe thrombocytopenia which persisted for nearly three years. The patient has remained in complete remission without therapy for 17 years and has now survived 22 years since diagnosis during which blood counts and results of bone marrow examinations and marrow chromosome studies have been normal. PMID- 6928729 TI - [Chemoimmunotherapy of acute lymphoid leukemia in children]. PMID- 6928730 TI - Rauscher "mink cell focus-inducing" (MCF) virus causes erythroleukemia in mice: its isolation and properties. PMID- 6928732 TI - Genetic polymorphism of rhodanese from human erythrocytes. AB - Rhodanese of human erythrocytes was monomorphic in most populations tested, but was polymorphic in Ahtna and Upper Tanana Indians. This enzyme is under the control of a single autosomal locus. PMID- 6928733 TI - Variability of glutathione S-transferase of human erythrocytes. AB - Glutathione transferase (GST) of human erythrocytes, while homogeneous upon electrophoresis, varied more than sixfold in amount in individuals. The levels of this enzyme were found to be inherited, but no practical way was devised to use this enzyme as a genetic marker. PMID- 6928731 TI - Use of side-hole endotracheal tube adapter for tracheal aspiration. A controlled study. AB - An alternate tracheal aspiration procedure using a side-hole endotracheal adapter was used in conjunction with transcutaneous oxygen (TcPO2) monitoring in 13 mechanically ventilated newborn infants. Decline in TcPO2 during suctioning and drop in neonatal heart rate were both substantially reduced using a procedure designed to preserve mean airway pressure. When compared with the routine procedure of disconnecting the endotracheal tube from the ventilator and suctioning via an end-hold adapter, this approach prevented precipitous and dangerous hypoxemia. PMID- 6928737 TI - Unilateral headgear: lateral forces as unavoidable side effects. PMID- 6928734 TI - Time and tide. AB - Timing of treatment is one of the main themes. The development of orthodontics in the United Kingdom is described against the background of a state-funded system. The scope and limitations of extraction therapy and removable appliance therapy are discussed. The principles of functional appliances are also described, as is the need for flexibility in appliance systems, to bring about maximum effect. PMID- 6928736 TI - Bimaxillary protrusion as a pathologic problem in the Thai. AB - The purpose of the study was to determine the nature and occurrence of bimaxillary protrusion in seventy-five students of the Faculty of Dentistry, University of Chiangmai, Thailand. The average age of the subjects was 22 years. Growth and development of facial dimensions were in a relatively stable configuration. Procedures included an evaluation of cephalographs, models, and photographs and an analysis of habits. A Steiner's analysis revealed the significance of the interincisal relationship for bimaxillary protrusion. In all cases the interincisal angle was below 124 degrees. In comparison with cases having an interincisal angle above 124 degrees, there was an increase in problems such as mouth breathing and tongue and lip habits, as well as a relative increase in tongue volume. Results of the study indicate that the etiology of bimaxillary protrusion is complex, involving environmental factors, soft-tissue function, volume, and habit. PMID- 6928735 TI - Experimental manipulation of head posture. AB - Variations in natural head position have been noted by previous workers to be associated with both dentoalveolar and craniofacial skeletal morphologic features. The determinants of cranial posture are as yet not known. Three experiments are described, dealing with the influence of (1) total nasal obstruction, (2) visual feedback deprivation, and (3) a combination of (1) and (2) on the posture of the cranium measured relative to a gravity-defined true vertical reference plane. The results indicate that total nasal obstruction results in all cases in an extended head position. Visual deprivation produces adaptation of a smaller magnitude and unpredictable direction. Combination of both experimentally induced conditions indicates a dominance of the respiratory adaptation in terms of postural response to these stimuli. PMID- 6928738 TI - Segment concept in arch pattern design. AB - The forming of arch wires is time consuming and often relies more on artistic interpolation than on scientific method, thus making the basis of orthodontic practice less precise. For years, various methods of designing arch wires have been tried and have been found inadequate. A new approach is advocated. Based on two decades of orthodontic practice and research, it elucidates a segment concept of arch pattern design, using three common reference measurements of the mandibular arch: canine width, molar width, and the sum of the mesiodistal diameters of the six mandibular anterior teeth. Normative data accumulated from 555 dental patients standardize basic measurements and variants. These data permit development of a finite number of arch patterns, adaptable to virtually all patients. A pattern, once selected, may be used as is or individualized to a specific arch form if necessary. Use of the segment concept might permit a much higher degree of clinical efficacy than that obtained with other methods of arch wire construction. PMID- 6928740 TI - The applicability of the occipital reference base in cephalometrics. AB - An occipital reference system, located outside the anterior half of the skull, has been designed which reveals sagittal as well as vertical relationships among facial components. The anatomic structures chosen had consistent behavior during growth, were located close to the midsagittal plane, and could be identified in a lateral cephalograph. Among the basal structures of the neurocranium, the occipital bone around the foramen magnum is the first to ossify. This appears to be indispensably necessary as the head is supported by the trunk precisely in the area of this individual bone. The ventrocaudal contour of the basal part of the occipital bone, anterior to the foramen magnum, and the internal occipital (sagittal) ridge, posterior to the foramen magnum, form the reference base. The intersection of the ventrocaudal contour and the anterior outlines of the occipital condyles serve as the key reference point (occipital point O') for constructing the occipital coordinate system whose horizontal axis is oriented to the earth's surface. This orientation is accomplished by a special photographic registration of the natural head position. The coordinate system has its center at the O' point and its abscissa thus adjusted to the horizontal. The use of a template permits the transfer of the occipital reference cross from the first to subsequent radiographs in the same relation to the occipital reference line as first registered. By the aid of a digitizer or a transparent graph paper with millimeter and centimeter squares on which the coordinate cross is marked, all measurements can be made on the radiograph directly as the reference points O' and O'' are marked on the radiograph itself, thus defining the position of the horizontal coordinate. In the past 50 years, a considerable amount has been learned about the function-form relationship in skeletal morphogenesis. It has been recognized that a faulty or poor postural behavior must be regarded as a major contributory factor to the maldevelopment in skeletal morphology and is taken into consideration in this reference system. PMID- 6928739 TI - The effect of orthodontic force application on the pulpal tissue respiration rate in the human premolar. AB - This study investigates the effect of an orthodontic force on pulpal respiration in the human premolar. The participants in this study required the removal of four first premolars for orthodontic treatment. After written consent was obtained, these teeth were used in the following manner. Randomly, the premolars on one side of the mouth were designated as experimental and the premolars on the opposing side served as controls. The four teeth were removed following a 3-day application of an orthodontic force. The pulp tissue was then extirpated and used for the investigation. A radioactively labeled carbon dioxide production system was used to evaluate the effect on pulpal respiration of the orthodontic force. It is thought that this method has been proved to provide a viable and sensitive biochemical analysis of tissue respiration on very small samples over short observation periods. The data were collected and prepared for statistical analysis. This investigation demonstrated that the pulp tissue respiration in seventeen subjects was depressed an average of 27% as a result of orthodontic force application. A positive correlation between the age of the participant and the amount of tissue respiratory depression was also demonstrated. It was therefore concluded that orthodontic forces of very short duration do cause biochemical and biologic pulpal tissue alterations and that orthodontic forces may be less biologically safe as the age of the patient increases. PMID- 6928741 TI - Holographic determination of centers of rotation produced by orthodontic forces. AB - A new tool for measuring tooth movement--laser holography--offers an accurate, noninvasive approach for determining movement in three dimensions. This in vitro study is designed to establish the required force system applied on the crown of a maxillary incisor that would produce different centers of rotation, as in lingual tipping, translation, and root movement. The relationship between moment to-force ratios and centers of rotation is shown. The experimental data are compared to theoretic approaches. With respect to the location of the center of resistance and centers of rotation, force systems needed to produce different centers of rotation are given for a central incisor of average root length. PMID- 6928744 TI - A comparative analysis of intrusion of incisor teeth achieved in adults and children according to facial type. AB - A comparison was made of incisor intrusion achieved in adults and children with deep bite. Facial type was also examined for effect upon intrusion achieved. Fifty-five cases treated with bioprogressive mechanics were studied cephalometrically; subjects included twenty-four adults and thirty-one children. Neither age nor facial type was found to be statistically related to the amount of incisor intrusion achieved in this sample. A method of measuring intrusion at the root apices was devised and was thought to give a more accurate indication of actual bodily intrusion. More external root changes during treatment were observed for adults than for growing children. There was a wide latitude in the amount of intrusion observed in both groups and in all three facial types. Considerable overbite reduction was noted for the sample, and intrusion was found to be but one factor in this. PMID- 6928742 TI - Biomechanics of differences in lower facial height. AB - A two-dimensional model which allows calculation of mechanical advantage of the human temporalis and masseter muscles is presented. The model is manipulated to demonstrate how selected differences in facial morphology affect the mechanical advantage of the muscles. The model is then used to evaluate the differences in mechanical advantage between patients with the long face syndrome and those with the short face syndrome. Differences in facial morphology between these two groups result in significant differences in the mechanical advantages of their muscles. Mechanical advantage may, in part, explain observed differences in bite force between the two groups. The model suggests that some surgical procedures used to correct facial disharmonies may have a significant effect on the mechanical advantage of the jaw muscles. PMID- 6928745 TI - Scientific evolution and homeostasis. PMID- 6928743 TI - Early and late surgery in craniofacial dysostosis: a longitudinal cephalometric study. AB - Longitudinal clinical and cephalometric case studies are presented for two groups of patients with craniofacial dysostosis. The first sample includes two infants who underwent an extensive stripping procedure that was extended inferiorly to involve not only the coronal, but also the sphenozygomatic suture. The second sample includes two adolescents with midfacial hypoplasia who underwent a fronto orbital-maxillary advancement. The extensive cranial stripping procedure had a favourable impact upon growth and development of the craniofacial structures, and longitudinal studies suggest the importance of promoting the growth potential of the bones contiguous to the affected sutures. Craniofacial surgery performed on adolescents results in a dramatic translocation of the skeletal and soft-tissue structures of the face. In contrast to early surgical intervention in infants in whom growth of the effected areas essential to the development of face and cranium was crucial, late surgery appeared to have little, if any, impact upon the development of the craniofacial skeletal structures that had been operated on. PMID- 6928746 TI - Use of computers in private practice. PMID- 6928747 TI - Gilles de la Tourette syndrome: clinical and family study of 50 cases. AB - Fifty patients with Tourette syndrome were evaluated; data included family history, clinical characteristics, response to haloperidol, and side effects during haloperidol therapy. Sixteen patients had a family history of Tourette syndrome, and another 16 had a family history of tics. Twenty-four families had more than 2 members with Tourette syndrome or tics. There was no preponderance of families with a Jewish, Eastern European background in this sample. Thirty-four patients had obsessive-compulsive behavior. Among the 50 patients there was a high frequency of sleep disturbance, learning disability, self-destructive behavior, inappropriate sexual activity, and antisocial behavior. Family history was significantly related to the occurrence of sleep disturbance, obsessive compulsive behavior, haloperidol response, and the frequency of side effects caused by haloperidol. The precise mode of genetic transmission in familial Tourette syndrome remains to be determined. PMID- 6928748 TI - Cytarabine-induced anaphylaxis. Demonstration of antibody and successful desensitization. AB - An anaphylactic episode occurred in a patient receiving cytarabine (Ara-C) for acute myeloid leukemia. Specific allergy of the patient to cytarabine was demonstrated in vivo by intradermal testing and in vitro by four-hour passive cutaneous anaphylaxis in guinea pigs. Desensitization to cytarabine was successfully performed. This case represents the first known report of both cytarabine anaphylaxis and densensitization, and provides immunologic evidence implicating an allergic reaction to cytarabine. PMID- 6928749 TI - Oropharyngeal tularemia. AB - A case of oropharyngeal tularemia mimicking a peritonsillar abscess is presented. This diagnosis should be entertained in patients who are seen initially with ulcerative-exudative pharyngitis with or without tonsillitis and whose routine cultures are negative and/or are unresponsive to penicillin. Institution of appropriate therapy depends largely on the clinical diagnosis because cultures on ordinary media are routinely negative, and it takes several days for antibody titers to reach diagnostic significance. PMID- 6928750 TI - Recent advances in urinary stone disease. PMID- 6928752 TI - Idiopathic urinary bladder stones of childhood. AB - An extensive study of the incidence of urinary stone formation has been made, with particular emphasis on idiopathic bladder stones in children, and the work carried out up to the present has been reviewed. The relation of the condition to the factors of historical time, ethnology, geography, socioeconomic status and climate has been studied in detail. While advances in our understanding of its aetiology have been made, the whole problem is still very far from being solved. PMID- 6928751 TI - The treatment of urinary stone disease. AB - Once a patient has been guided past any acute problems of pain, obstruction or urosepsis, the stone type has been identified, and all metabolic problems and dietary indiscretions have been revealed, the physician treating a stone patient is faced with the frequently more arduous problems of treating or preventing the patient's stone disease. Several generalizations can be made about the strategies requisite for successful management of the long-term problem, and the problem is discussed in this paper in general and in some detail. PMID- 6928754 TI - The calibre of the midureter. AB - The mean circumferences of twenty-eight ureters have been measured at one centimetre intervals from the midpoint. Midureteric constriction was not a regular feature. PMID- 6928753 TI - Synchronous combined transvaginal-transvesical repair of vesicovaginal fistulas. AB - Nine cases of vesicovaginal fistula which followed hysterectomy, with or without radiotherapy, are presented. The repair by the above-mentioned technique eventually led to successful closure in all cases. A strong argument can now be advanced that this is the technique of choice in the large, high postoperative type of vesicovaginal fistula which is now the common type of fistula seen in affluent countries. PMID- 6928755 TI - Ruptured abdominal aortic aneurysm: long-term survival after operation. AB - The long-term follow-up of 65 patients surviving surgery for ruptured abdominal aortic aneurysms is presented. Fifty-six per cent of these patients were alive at the time of review, having survived for a mean period of 36 months. The majority were enjoying a quality of life similar to that experienced before operation. Preexisting ischaemic heart disease did not alter the long-term prognosis. Cumulative survival curves for this group of survivors approximated both the survival curve for the average matched Australian population and similar curves constructed for patients operated upon electively for abdominal aortic aneurysms. PMID- 6928756 TI - Clinical experience with the Smeloff-Cutter prosthesis: one to twelve year follow up. PMID- 6928757 TI - Surgical treatment of cervical lymph nodes in carcinoma of the tongue. AB - A series of 56 cases of carcinoma of the anterior two-thirds of the tongue treated surgically was reviewed. Lymph node metastasis occurred in 50% of cases. There was 22% false-negative clinical assessments of lymph node status for the ipsilateral side of the neck. Because of these and the difficulty in ensuring early treatment of subsequent node metastasis, concurrent ipsilateral radical neck dissection is recommended. When the ipsilateral side of the neck was involved the contralateral side has 22% false-negative assessments. Elective radical neck dissection for the contralateral side is recommended in this situation. The overall five-year survival was 50.6%, and was greatly affected by the status of the neck lymph nodes. PMID- 6928758 TI - The management of bleeding gastric ulcer: a prospective study. AB - In a prospective study of six years' experience with a haematemesis and melaena unit from 1972 to 1978, there were 98 admissions of patients with bleeding gastric ulcer. There were ten deaths, giving a mortality of 11%. Forty-one patients were treated by emergency surgery with seven deaths, an operative mortality of 17%. All ten deaths occurred in the first four years; there were no deaths during the final two-year period (38 admissions). In retrospective studies at Prince Henry's Hospital, Melbourne, it was found that the mortality for bleeding gastric ulcer was 17% to 18% for the period 1951 to 1970. It is concluded that a prospective system of management with an active policy of early endoscopy and surgery and regular audit of results reduces the mortality from bleeding gastric ulcer. PMID- 6928759 TI - Systemic manifestations of chronic ulcerative colitis refractory to colectomy. AB - In this paper, two cases of chronic ulcerative colitis displaying systemic manifestations are discussed. Each case illustrates the refractoriness of the systemic manifestations to colectomy and the total resolution of the manifestations by additional proctectomy. The implications of these clinical observations in relationship to the aetiology and therapy of ulcerative colitis are discussed. PMID- 6928760 TI - The management of perforated diverticulitis with diffuse peritonitis. AB - In a ten-year period 53 patients presented with perforated colonic diverticular disease with diffuse peritonitis. Eight patients died--all with uncontrolled intraabdominal sepsis. Various surgical techniques were employed. None of the 12 patients having immediate resection of the affected bowel segment died. There was no mortality from subsequent operations in any form of staged treatment. Primary resection without anastomosis is supported as the treatment of choice for this condition. PMID- 6928761 TI - Is the ascending colon dispensable in resection for Crohn's disease? AB - Resection for chronic ileocaecal Crohn's disease may be conservative with ileo ascending-colon anastomosis, or be extended to standard right hemicolectomy. The two operations have been compared to determine whether preservation of the ascending colon is advantageous. Stool frequency, consistency and weight were similar after the two operations. A slower stool transit time was the only clinical difference associated with preservation of the ascending colon. An adaptable and patient-acceptable technique for domicillary collection of stools is described. PMID- 6928762 TI - Squamous carcinoma of thyroglossal duct remnants: a case report and review of the literature. AB - The first reported case in Australia of a squamous carcinoma arising in a thyroglossal duct remnant is presented. This case shows the previously unreported feature of associated hyperthyroidism. PMID- 6928763 TI - Cysticercosis of the fourth ventricle: a report of two cases. AB - Cysticercus cellulosae, the larva of the pork tapeworm, has a predilection to encyst within the central nervous system. It is common in endemic areas, such as Central and South America, but rare in Australia. The clinical and radiological findings in two patients with fourth ventricular cysts are described. PMID- 6928764 TI - To define sufficient subjects. AB - The problem of how many subjects are required for a particular investigation can be solved. Techniques developed to allow experimenters to determine the statistical power of their experiments can be adapted to this end provided that the investigator is prepared to define the significance level and, more importantly, the minimum strength of experimental effect that is of interest. The experience described in this article demonstrates that the process demands consideration of a number of factors like the nature of the dependent variable, the form of the decision being made, and the minimum difference between conditions which has practical consequence. PMID- 6928765 TI - Thyroglossal duct remnants in childhood. AB - The most common cause of a midline cervical lesion in childhood is a thyroglossal duct remnant. It is disappointing to find that although the embryology and rationale of definitive treatment have been well understood for many years, there persists a high incidence of inadequate surgical treatment in the first instance, especially in the hands of general surgeons. PMID- 6928766 TI - Anaerobic bacteria, the colon and colitis. AB - Anaerobic bacteria constitute more than 90% of the bacteria in the colon. An anaerobic environment is needed to maintain their growth and the production of short-chain fatty acids by these bacteria from carbohydrates. Short-chain fatty acids are rapidly absorbed and essential for metabolic as well as functional welfare of the colonic mucosa. The importance of these acids in water absorption and in the patogenesis of colitis is discussed in relation to the concept of "energy deficiency diseases" of the colonic mucosa. PMID- 6928767 TI - Chirurgery. PMID- 6928768 TI - Renal impairment and its reversibility following variable periods of complete ureteric obstruction. AB - There is debate concerning the time course and degree of recovery possible after relief of complete unilateral ureteric obstruction. This study in dogs investigates these features. One ureter was occluded for varying periods, and then reimplanted into the bladder. Recovery was monitored by Tc-Sn-labelled diethylene triamine penta acetic acid (D.T.P.A.) scans and renograms together with creatinine clearance studies. The morphological changes were also studied. There was found to be a progressive loss of functional recovery with increasing periods of obstruction, though this was dramatically improved by contralateral nephrectomy once recovery had stabilized. Increased radial scarring developed in the kidney following increasing periods of obstruction. PMID- 6928769 TI - The clinical approach to the aetiology of recurrent urinary calculi. PMID- 6928771 TI - A simple apparatus for creating experimental burns. PMID- 6928770 TI - Why do surgical packs cause peritoneal adhesions? AB - Our experiments in the Porton rat have shown that the foreign debris from surgical sponges left in the peritoneal cavity after use is not the cause of peritoneal adhesions. Instead, the abrasive effect of introducing the sponge produces mesothelial trauma. This is the stimulus for an inflammatory response, followed by adherence of adjacent involved peritoneal surfaces. Adhesions formation did not occur between the abraded peritoneal surfaces of mobile intraabdominal viscera, which suggests that intestinal motility in the early postoperative period is important in the prevention of adhesions. PMID- 6928772 TI - Surgical research in Australasia. AB - An analysis has been made of the 642 papers presented to the Surgical Research Society of Australasia between 1962 and 1978. Most areas of research have maintained a relatively stable level of productivity over the period examined. However, while tumour immunology, education, and microsurgery have attracted increasing interest, that of transplantation immunology and cardiovascular research appeared to be decreasing in recent years. The most commonly investigated body systems were gastrointesinal (27%), cardiovascular (21%), and genitourinary (17%). The most commonly studied scientific disciplines were metabolism/biochemistry (22%), physiological measurement (17%), immunology (10%), oncology (9%), and transplantation (8%). Less than 3% of papers related to controlled clinical trials. PMID- 6928773 TI - Effects of pulmonary x-irradiation and pulmonary tumor burden on hypoxia tolerance of mice. AB - Hypoxia tolerance was measured in female C3H mice which had been given single thoracic X-ray exposures or which were bearing pulmonary tumors. Thoracic X-ray exposures ranging from 500-1500 rad had no significant effect on hypoxic tolerance for up to 56 d following irradiation. The presence of pulmonary tumors from the Dunn osteosarcoma had no significant effect on hypoxic tolerance until a tumor burden of about 200 mm3 was reached. It is concluded that neither a pulmonary radiation history nor moderate lung tumor burdens militate against using reduced oxygen environments in radiotherapeutic regimens to treat pulmonary tumors. PMID- 6928775 TI - Geriatric medicine. PMID- 6928774 TI - Malignant transformation in Mikulicz's disease. PMID- 6928777 TI - 'Dentistry ... a branch of medicine'. PMID- 6928776 TI - Myocardial infarction mortality in the 1970's. PMID- 6928778 TI - Bleaching discoloured root-filled teeth. PMID- 6928780 TI - Confectionery consumption levels. PMID- 6928779 TI - 'Double teeth'. PMID- 6928781 TI - The 16 to 20 study. PMID- 6928782 TI - What price sponsorship? PMID- 6928784 TI - An examination of the personality of dental patients who complain of retching with dentures. PMID- 6928785 TI - A simple splint for segmental orthognathic surgery. PMID- 6928783 TI - Dental health in Japan and England and Wales. A comparison of National Dental Surveys. PMID- 6928786 TI - Insurance claim assessment. A report on procedure. PMID- 6928787 TI - Malignant myelomonocytic cells after in vitro infection of marrow cells with Friend leukaemia virus. AB - Infection of long-term BDF1 marrow cultures with Friend leukaemia virus complex (FLV) induced transformed cells with myelomonocytic characteristics, which were isolated only 14 days after the viral infection. Criteria for transformation were growth in suspension cultures and high plating efficiency in agar. The lymphatic leukaemia virus (LLV) replicates in these suspension cultures, but the spleen focus-forming virus (SFFV) component of the FLV complex has not been detected. Injection of the transformed cells into syngeneic neonatal or adult mice leads to the development of leukaemia which can be demonstrated to be of donor origin by the presence of two metacentric marker chromosomes which are also seen in the cultured cells. PMID- 6928788 TI - Enzymatic sulfation of Triton X-100. AB - Triton X-100 increased incorporation of [35S]sulfate into lipid-soluble substances when it was incubated with the high-speed supernatant enzymes of bovine or sheep adrenal cortex or rat liver, kidney or brain. Thin-layer chromatographic comparison of these compounds with chemically synthesized standards indicated that sulfate derivatives of Triton X-100 oligomers were formed in the liver and adrenal supernatant enzyme preparations. Further evidence for Triton X-100 sulfation by these enzymes was obtained by the use of [3H]Triton X-100 and purified Triton X-100 oligomers. No discernible sulfation of Triton X 100 occurred in kidney or brain high-speed supernatant enzyme preparations. A series of [35S]sulfate-containing substances, which closely resembled the homologous series of [35S]sulfate-labeled Triton X-100 oligomers formed by adrenal cortex enzymes, were formed in detergent-free adrenal incubates. Their chromatographic behavior suggests that they are not steroid sulfates. The kidney supernatant enzyme fraction was shown to contain steroid sulfotransferase activity; sulfation of cholesterol, dehydroepiandrosterone, pregnenolone, cholic acid and lithocholic acid was stimulated by the presence of Triton X-100. PMID- 6928789 TI - Differentiation of human leukemias in response to 12-0-tetradecanoylphorbol-13 acetate in vitro. AB - Leukemic cells from patients with acute myeloid leukemia underwent morphological, functional, and histochemical changes within 24-48 hr after treatment with 1.6 x 10-18 M 12-0-tetradecanoylphorbol-13-acetate (TPA). The changes included adhesion to the plastic substrate, a 4-6-fold increase in the number of phagocytic cells, and an increase in the number of alpha-naphthyl-acetate esterase (alpha-NAE) positive cells. In contrast, TPA treatment of cells from patients with acute lymphoblastic leukemia caused some aggregation of cells in suspension, but no changes in adhesion, phagocytosis, or alpha-NAE. Of the four cases of undifferentiated or unclassified leukemias studied, two failed to respond to TPA, one responded with a myeloid (adhesion) pattern, and one with a lymphoid (aggregation) pattern. These data suggest that leukemic myeloblasts retain the ability to express a variety of differentiated functions, and in some cases, it may be possible to use TPA as a tool to test the differentiative potential of undifferentiated human leukemias. PMID- 6928790 TI - Another case of t(4;9;22) in chronic myeloid leukemia. PMID- 6928792 TI - Design of educational facilities for deaf children. PMID- 6928791 TI - The efficiency of strict reverse isolation and antimicrobial decontamination in remission induction therapy of acute leukemia. AB - The efficiency of strict reverse isolation and antimicrobial decontamination in remission induction therapy of acute leukemia was studied retrospectively in 47 patients who were treated with a standardized aggressive chemotherapy of daunorubicin and cytosine arabinoside. Twenty-two patients were treated in strict reverse isolation with antimicrobial decontamination and 25 patients in the open ward without any measures against infections. In the patients in isolation the incidence of new infections per patient was 0.77 compared to 1.42 in the control group. The rate of complete remissions was 77% in the patients in isolation vs. 56% in the control patients. PMID- 6928793 TI - JCAH accreditation and the hospital library: a guide for librarians. AB - The continuing effort to develop standards for libraries in health care institutions has resulted in the creation of two broad groups of standards: (1) quantitative and specific, and (2) qualitative and flexible. The library standards of the Joint Commission on Accreditation of Hospitals (JCAH), a major example of the second type, were revised and expanded considerably in 1978, bringing them into line with standards for other hospital departments. Possible areas of unclarity or difficulty for the librarian in complying with the revised JCAH standards are discussed, including those relating to staffing, consultants, library technicians, analysis of resources, assessment of needs, documentation, policies and procedures manuals, and the library committee. The JCAH site visit, including preparation of the Hospital Survey Profile, gathering information for the surveyor, and the summary conference, offers opportunities to librarians to participate in an institution-wide effort, to upgrade management practices, and to demonstrate the need for, and effectiveness of, library services in their hospitals. PMID- 6928794 TI - Studies on genetic resistance to leptospirosis in pigs. PMID- 6928795 TI - Expression of viral RNA in Friend virus-induced erythroleukemia cells. AB - The regulation of expression of the Friend virus complex (FV) was studied in clones of H-2 congenic erythroleukemia cell lines. Molecular probes specific for each of the two FV components were generated and hybridized to RNA extracted from clones differing with respect to virus production or viral envelope antigen expression. Sequences representing the defective component of FV continued to be transcribed in cells regardless of virus production. The presence of helper virus specific sequences, however, was shown to be directly related to virus expression. Molecular hybridization with cytoplasmic and nuclear RNA extracted from the H-2 congenic clones representing various stages of viral expression demonstrated a direct correlation between the level of transcription of FMuLV specific sequences and the degree of virus expression. These data suggest that regulation of FV expression is primarily related to the cessation of helper virus transcription in the cell lines studied. In this paper we provide further evidence that the defective viral components is responsible for the rapid malignancy associated with Friend disease. PMID- 6928797 TI - [Height relationship of dental areas and the biometric norm of the occlusal plane]. PMID- 6928796 TI - [X-ray study of tooth enamel structure after the use of toothpaste containing fluoride and a 2% NaF solution]. PMID- 6928798 TI - [Survey of pathological changes on the face, oral cavity and tissues of the marginal periodontium in sclerodermas]. PMID- 6928799 TI - [The relationship of diabetes mellitus to periodontitis]. PMID- 6928800 TI - [Experimental studies of biocompatibility of various materials for root fillings from the point of view of methodology and histopathology]. PMID- 6928801 TI - [Lymphangioma in the orofacial region in children]. PMID- 6928802 TI - [Statistical evaluation of injuries of the facial skeleton at the Department of Maxillofacial Surgery at the Stomatological Clinic II in Brno]. PMID- 6928803 TI - [Long-term follow-up study after Kostecka's operation for prognathism in the orthopantomographic aspect]. PMID- 6928804 TI - Stabilization of 20 beta-hydroxysteroid dehydrogenase by glycerol. PMID- 6928806 TI - Relationship between the eruption of mandibular first permanent molar and growth changes of adjacent structures. AB - The relationship between the eruption of mandibular first permanent molar and growth changes of the adjacent structures was statistically investigated on 16 children during the active eruption of the tooth. Semiannual records of 45-degree oblique cephoalgrams and dental casts were used as materials. The factor analysis with orthogonal rotation was applied and the pattern of associations was revealed by the following six factors: Factor 1. Proximity factor. With larger mesiodistal tooth diameter, the tooth tends to be more mesially positioned. Factor 2. Eruption factor. The tooth erupts rapidly, nearing the distal surface of mandibular second deciduous molar more quickly and simultaneously widening the space posterior to the dental arch more rapidly. Factor 3. Root development factor. As the root develops faster, the interdental space tends to close more rapidly. Factor 4. Eruption rate factor. As the tooth nears the occlusal plane, the rate of eruptive movement decreases. Factor 5. Tooth uprighting factor. With more amount of space posterior to the dental arch, the subsequent uprighting of the long axis of the tooth can be expected. Factor 6. Tooth inclination factor. Inclination of the long axis of the tooth crown is relatively independent from the variables examined. PMID- 6928807 TI - Anaerobic, gram-positive, pleomorphic rods in human gingival crevice. AB - Sixty-two strains of anaerobic, gram-positive, pleomorphic rods were isolated from the gingival crevice of individuals clinically free from peridontal disease, and examined for biochemical characteristics, cellular and colonial morphology, and acid end-products from glucose fermentation. None of them produced indole, hydrogen sulfide, or catalase, but all hydrolysed esculin. Seven, 10 and 45 of 62 strains were identified as Bifidobacterium, Actinomyces naeslundii, and Actinomyces israelii, respectively, on the basis of biochemical characteristics. PMID- 6928808 TI - Aerobic gram-positive pleomorphic rods isolated from dental plaque and gingival crevice. AB - A typical gram-positive pleomorphic aerobe is Rothia dentocariosa. However, there exist many organisms having similar characteristics (Rothia-like organisms). The purpose of this study is to isolate Rothia dentocariosa and Rothia-like organisms from the healthy and diseased sites of the oral cavity and to clarify the characteristics of those organisms. A total of 342 strains were isolated in this study, and 188 strains were identified as gram-positive pleomorphic rods. Seventy seven typical strains of 188 isolates were examined physiologically and biochemically, and they were classified as follows: 1) 20 strains of A. viscosus; 2) 3 strains of A. naeslundii; 3) 26 strains of Rothia dentocariosa; 4) 2 strains of Bacterionema matruchotii; 5) 15 strains of Corynebacterium; 6) 7 strains of Nocardia; and 4 unknown strains. The strains of Rothia dentocariosa were mainly isolated from the dental plaque (24 of 26 isolates), and they had the ability to adhere on to the glass surface, and 5 of 26 strains of Rothia dentocariosa showed the ability of gelatin liquefaction. PMID- 6928809 TI - Enzymic color development of urinary 3 alpha-hydroxysteroids on thin-layer chromatograms. AB - I describe the use of 3 alpha-hydroxysteroid dehydrogenase (EC 1.1.1.50) for enzymic color development of 3 alpha-hydroxysteroids. Urinary 3 alpha hydroxysteroids are converted to 3-ketosteroids by the enzyme, and the NADH formed is reacted with 2-p-iodophenyl-3-p-nitrophenyl-5-phenyl-tetrazolium chloride and "diaphorase" to form the colored formazan. The dye so formed on a thin layer chromatographic plate is measured by densitometoric scanning. I illustrate use of this method by showing results for urinary excretion of 3 alpha hydroxysteroids by some various sorts of patients. PMID- 6928810 TI - Familial X-linked mental retardation with a marker X chromosome and its relationship to macro-orchidism. AB - It has been suggested that the form of X-linked mental retardation with macro orchidism and the form associated with a marker X chromosome (fragile site at Xq27 or 28) are the same entity. Although our data support this hypothesis, one family from the literature does not. Data are presented suggesting that actual measurements are required for accurate evaluation of testicular size. PMID- 6928805 TI - Diazepam-induced suppression of jaw opening reflex in rats. AB - Effec of an i.p. injection of diazepam on the jaw opening reflex evoked by electrical stimuli applied to the tooth pulp innervated by mainly high threshold afferents and the lower lip innervated by low threshold afferents was investigated using Wistar albino rats. Small doses of diazepam, less than 2.5 mg/kg, suppressed to the same degree the jaw opening reflexes evoked by stimulation of tooth pulp or lower lip. However, when larger doses thab 5.0 mg/kg were administered, the suppression of tooth pulp-evoked jaw opening reflex was greater than that of lower lip-evoked one. In this case, the period of suppression of tooth pulp-evoked jaw opening reflex was longer than that of lower lip-evoked one. It is concluded that (1) the pain relieving effect of diazepam appears only when larger doses tha 5.0 mg/kg are administered and that (2) the pain-relieving effect lasts longer than muscle-relaxative effect of diazepam. PMID- 6928811 TI - Gc serum groups and schizophrenia. AB - In an epidemiological study of schizophrenia in a North Swedish isolate, Book et al. (1978) reported an association between schizophrenia and the genetic marker Gc2. In an attempt to confirm this observation, we examined a series of schizophrenic patients from Vasterbotton County in Northern Sweden. In our material there was no difference between schizophrenic patients and controls with respect to the frequencies of Gc groups or genes. A reanalysis of the material by Book et al. (1978) showed that schizophrenics compared to controls had a significant increase in the frequency of the Gc 2-1 group, but not of the Gc2 gene. The Gc distribution in the material by Book et al. (1978) was similar to that previously reported by us in a series of patients with cycloid psychosis. PMID- 6928812 TI - Hemorrhagic pancreatitis in a patient with glycogen storage disease type I. AB - A 17-year-old female with glycogen storage disease type I (GSD-I) died suddenly with hemorrhagic pancreatitis. She had a long-standing history of hyperlipidemia that did not respond to a regimen of frequent daytime and nocturnal intragastric feeding. Although pancreatitis is a well-known complication of hyperlipidemia, there are no reports to our knowledge of pancreatitis causing sudden death in patients with GSD-I. Pancreatitis must be added to the growing list of complications that can occur in long-term survivors with GSD-I, and should be considered when these patients present with abdominal pain. PMID- 6928814 TI - Ineffectiveness of laetrile in the treatment of acute lymphoblastic leukemia. AB - Much controversy remains over the use of laetrile in the treatment of leukemia. Public opinion has been responsible for several state legislatures enacting bills allowing the use of laetrile for patients with leukemia and other malignancies. We recently cared for a 3 1/2-year-old child with acute lymphoblastic leukemia, who had low initial white blood cell count, limited organomegaly, and absence of T or B cell markers. A good prognosis was anticipated. Conventional therapy was interrupted for long periods of time with laetrile. Laetrile was ineffective in maintaining or inducing remission. Despite favorable prognosis, the child developed several relapses and died with widespread infiltration of leukemia in the central nervous system, bone marrow and viscera. PMID- 6928813 TI - Two unrelated children with distal long arm deletion of chromosome 7: clinical features, cytogenetic and gene marker studies. AB - Two phenotypically abnormal, unrelated children with deletion of the distal segment of 7q (7q32 leads to pter) are described. In one instance the mother was the carrier of a balanced translocation between chromosomes 6 and 7, and in the second case the deletion was a de novo event. Their phenotype were compared to previously reported cases and found to have many non-specific clinical features in common. Gene marker studies for some of the genes tentatively localized to chromosome 7 showed no anomalous segregation. The Hageman coagulation factor (Factor XII) activity in both probands was normal, and heterozygosity for alleles of the Kidd blood group in the first proband excludes assignment of the Kidd locus to the distal portion of chromosome 7q. PMID- 6928815 TI - The death of Chad Green. PMID- 6928816 TI - Evaluation of 13-cis retinoic acid in lamellar ichthyosis, pityriasis rubra pilaris and Darier's disease. AB - A new synthetic oral retinoid, 13-cis retinoic acid, is fairly well tolerated in patients and appears to be effective in those with Darier's disease and lamellar ichthyosis. It is less effective in those with pityriasis rubra pilaris. The mechanism of action of 13-cis retinoic acid in disorders of keratinization is unknown at the present time; however, it does not appear to cause lysosomal proliferation in therapeutic doses. PMID- 6928817 TI - Treatment of gastrointestinal disorders of pregnancy. PMID- 6928819 TI - Friend cell variants temperature-sensitive for growth. PMID- 6928820 TI - [The importance of practical admission tests in dental education]. PMID- 6928818 TI - Testicular steroid sulfotransferases: comparison to liver and adrenal steroid sulfotransferases of the mature rat. AB - Steroid sulfotransferase activity was investigated in cytosol fractions of whole testes, isolated seminiferous tubules, isolated interstitial tissue, livers, and adrenal glands of mature male rats. Enzyme activity was measured by incubating cytosol fractions with 3H-labeled pregnenolone, dehydroepiandrosterone, testosterone, or estradiol and the active sulfate donor 3'-phosphoadenosine-5' phosphosulfate. Testicular steroid sulfotransferase activity was found in seminiferous tubules. 3 beta-Hydroxysteroid sulfotransferase activity of seminiferous tubules exhibited a pH optimum of 10 in contrast to a pH optimum of 5 reported for cytosol fractions of rat liver. Marked differences in substrate specificity were demonstrated in the three tissues. The preferred substrate for the 3 beta-hydroxysteroid sulfotransferase in seminiferous tubules was pregnenolone, and in liver it was dehydroepiandrosterone, No 3 beta hydroxysteroid sulfotransferase activity could be detected in cytosol fractions of adrenal glands. Testosterone was sulfated only by hepatic cytosol fractions. All three tissues contained estrogen sulfotransferase activity. These data suggest that the 3 beta-hydroxysteroid sulfotransferase of seminiferous tubules is distinct from the 3 beta-hydroxysteroid sulfotransferase of liver. These differences may relate to different functions of steroid sulfates in liver and testes. PMID- 6928821 TI - [Comparative study of fissure sealants]. PMID- 6928823 TI - [Plate osteosynthesis for the treatment of mandibular fractures]. PMID- 6928822 TI - [Osteoradionecrosis of the mandible]. PMID- 6928824 TI - [Correction of prognathism by therapy of osteomyelitis, resulting from mandibular fracture]. PMID- 6928825 TI - [Clinical and histomorphological features of pregnancy granuloma (angiogranuloma)]. PMID- 6928826 TI - [Protective properties of toothpastes in experimental caries in rats]. PMID- 6928827 TI - [Supply of toothbrushes in Hungary]. PMID- 6928828 TI - [Supplement to the Regulation of the Hungarian Dental Society, 1979]. PMID- 6928829 TI - Symposium on periodontal restorative interrelationships. PMID- 6928831 TI - A systematic approach to the interpretation of tooth mobility and its clinical implications. PMID- 6928830 TI - The interdental space. AB - There is a close relationship between the contact, contour, and shape of the teeth that creates the interproximal space with the help of the interdental gingiva. The interdental gingiva, composed of the facial and lingual papillae and the col, is a unique area anatomically and histologically. The high incidence of caries and periodontal disease in the interproximal area is partially the result of this histologic and anatomic make-up and the great accumulation of bacterial plaque. In restorative dentistry, it is important to recreate an interproximal area that will minimize a long facial-lingual col area, provide adequate space for interdental gingiva, minimize food impaction and retention, and allow for ease in plaque removal by the patient. PMID- 6928832 TI - Management of periodontal disease in patients with occlusal abnormalities. AB - 1. Periodontitis is a bacterial, plaque-induced disease. 2. Periodontal tissues may be affected simultaneously by inflammatory changes and traumatic changes. 3. Unless a traumatic injury is diagnosed, the occlusion should not be altered as part of the periodontal treatment. There is no place for prophylactic treatment of the occlusion. 4. Occlusal adjustment, occlusal bite splints, orthodontic treatment, and restorative dentistry are all means to treat the occlusion. 5. Occlusal treatment is generally performed after control of the inflammatory periodontal changes by root preparation and oral hygiene. 6. Restorative procedures should be carried out at least one to two months after completion of periodontal surgery. 7. The aim of occlusal therapy should be the establishment and maintenance of stable occlusal relationships and the restoration of an optimal occlusal function. PMID- 6928833 TI - Orthodontic movement in periodontal therapy. PMID- 6928834 TI - Electrosurgical management of soft tissues and restorative dentistry. AB - Proper use of oral electrosurgery permits rapid, full management of soft-tissue problems related to mouth preparation for fixed and removable prosthodontics. The ability to control precisely the zone of coagulation enables the dentist to carve, sculpture, or modify the soft-tissue contours with or without hemorrhage. Restorative dentists possess a high degree of artistic sculpturing skills that can be effectively utilized to harmonize restorative and soft-tissue contours. The life expectancy and function of all fixed and removable restorations depend upon optimal health of the supporting tissues for biomechanical compatibility. Modern electrosurgical techniques and equipment make it possible for the general practitioner, as well as the specialist, to deliver more timely and more comfortable improved fixed and removable appliance therapy to their patients. PMID- 6928839 TI - HLA-antigens and diabetic retinopathy: a different view warranted. PMID- 6928835 TI - Biological implications of dental materials. AB - Testing of the biologic effects of dental materials has lagged far behind the characterization of their mechanical and physical properties. Various biologic type tests, whether in vitro or in vivo, have often produced conflicting or confusing data. The objective of this article was to bring together the results of various investigations to form guidelines for the safest use of dental materials. Since many interactions between dental materials and living tissue have not been definitively established, a conservative approach was taken. The clinician who heeds the data summarized for the dental materials presented here will have the greatest probability of obtaining a benign chemical response of soft and hard tissues. PMID- 6928836 TI - The selection of occlusal patterns in periodontal therapy. AB - Posterior and anterior occlusal anatomy is discussed primarily from the standpoint of occlusal contact relationships. A few general principles of occlusal morphology have been presented. Certain occlusal considerations have been discussed as they relate to selective grinding as well as to restorative dentistry and orthodontics. PMID- 6928837 TI - The maintenance phase of dental therapy. AB - Clinical research has shown beyond doubt that maintenance of oral health in restored or periodontally treated dentitions depends only to a relatively small degree on the therapeutic appliances and techniques used. It is the combination of periodic professional tooth debridement and fluoridation by the dental team, detailed and uncompromising instruction of individualized home care techniques, and ensuing optimal daily plaque control by a well-informed, trained, and motivated patient that determines, almost exclusively, the long-term success of dental therapy. It is, therefore, imperative that dental restorations and periodontal procedures be compatible with the requirements for effective maintenance care. PMID- 6928840 TI - Accreditation problems: how survey reports are processed. PMID- 6928838 TI - Alteration of a human lymphoblastoid cell line, REH6 during subsequent cultivation. AB - Chromosomal and isoenzyme alteration of a human leukemia cell line, REH6, is shown during 80 subsequent passages. No correlation between these properties could be found. PMID- 6928842 TI - Relative roles of toothbrushing, sucrose consumption and fluorides in the maintenance of oral health in children. PMID- 6928841 TI - Problems involved with the use of comforters. AB - Comforters have been associated with three areas of concern for the dental profession: rampant caries, malocclusion and gingival recession. The most serious of these, rampant caries, is associated with the practice of sweetening the comforter. Every effort should be made to eliminate this hazard to the dentition by means of dental health education for the community, especially of pregnant and nursing mothers. An open question remains on whether unsweetened dummy sucking should be promoted in order to intercept malocclusions likely to arise from digit sucking. PMID- 6928845 TI - Multi-technique approach for treating malocclusions. PMID- 6928844 TI - Fluoride mouthrinsing by orthodontic patients. PMID- 6928846 TI - President's message. PMID- 6928847 TI - Communicate! PMID- 6928848 TI - [Quantitative study of the effect of occlusal hypofunction on periodontal ligament with and alveolar osteoclastic resorption in rats]. AB - An occlusal hypofunction has been produced by unilateral extraction of the maxillary molars in the rat and its effect has been studied on the antagonistic lower molars during a period of 15 days to 3 months. The quantitative analysis showed that the alveolar width decreased very significantly as early as the fifteen day. This fact was due to a decrease of the periodontal membrane width from the fifteenth day. This decrease was observed until 1 month on the alveolar surface undergoing apposition. The decrease of the alveolar width was also related to a drop of the periodontal membrane width as soon as fifteen days on the surface in resorption. The radicular width remained constant, confirming that it was the bone apposition and not the cementum apposition which caused the narrowing of the periodontal membrane. The quantitative study of the osteoclastic resorption showed that this later decreased but in a non significant on the alveolar surface undergoing remodeling. PMID- 6928843 TI - The treatment of medically handicapped children. AB - There are a number of chronic medical conditions in which dental care for the child is of vital importance as their general health may be put at serious risk if they develop dental disease or require dental treatment. The more common medical conditions which cause these problems are summarized and the associated risks discussed. The need for the dentist providing care to have sufficient knowledge of the medical conditions and forms of treatment which put the child at risk is stressed. Some of the other problems which occur during dental care of chronically sick children are considered, and these include paediatric medication and certain types of diet therapy which have an adverse effect on dental health, provision of dental treatment and the emotional and social problems which occur in families in which there is a seriously ill child. Finally, the aims of dental care for this group of patients is discussed. PMID- 6928849 TI - Presence of erythroglycan on human K-562 chronic myelogenous leukemia-derived cells. AB - Total glycopeptides from human K-562 cells, labeled metabolically with [3H]glucosamine or [3H]mannose, were prepared by extracting the cells with organic solvents to remove lipids and by digesting the residue with pronase. 3H labeled glycopeptides were fractionated on Sephadex G-50 revealing a high molecular weight fraction (Mr = 7,000 to 11,000), comprising approximately 10% of the [3H]glucosamine and 25% of the [3H]mannose label. Digestion of this glycopeptide fraction with endo-beta-galactosidase from Escherichia freundii, specific for a repeating structure of Gal(beta 1 leads to 4)GlcNAc(beta 1 leads to 3), results in the following four products as resolved by Bio-Gel P-2 gel filtration: 1) a disaccharide with the structure beta-2-deoxy-2-acetamidoglucosyl leads to beta-galactose; 2) a trisaccharide with the structure beta-galactosyl leads to beta-2-deoxy-2-acetamidoglucosyl leads to beta-galactose; 3) a tetrasaccharide with the sequence alpha-N-acetylneuraminyl leads to beta galactosyl leads to beta-2-deoxy-2-acetamidoglucosyl leads to beta-galactose; and 4) a larger, complex fragment which contains mannose and beta-2-deoxy-2 acetamidoglucose and which is probably the protein linkage region. In addition, visualization of radiolabeled glycoproteins by fluorography on polyacrylamide gels revealed a 105,000-dalton "Band 3"-like glycoprotein and other bands that were sensitive to endo-beta-galactosidase. These results indicate that the K-562 cell line bears a glycopeptide, erythroglycan, which has been found on erythrocytes, and that this polymer is expressed mainly in the fetal form as a linear chain. PMID- 6928850 TI - Synthesis of 2-bromoacetamidoestrone methyl ether and study of the steroid binding site of human placental estradiol 17 beta-dehydrogenase. AB - To characterize further the active site of human placental estradiol 17 beta dehydrogenase (EC 1.1.1.62), we have synthesized 2-bromoacetamidoestrone methyl ether. The affinity-labeling steroid is a substrate for the homogeneous enzyme. It inactivates the enzyme in a time-dependent, irreversible manner which follows pseudo-first order kinetics. Further, inactivation conducted with varying steroid concentration displays saturation kinetics. When 1.7 x 10(-6) M enzyme is inactivated by 2.6 x 10(-4) M 2-bromoacetamidoestrone methyl ether, the presence of an equimolar concentration of estradiol or 5.2 x 10(-4) M concentrations of NAD+, NADP+, or NADPH markedly slow the rate of inactivation. Bromoacetate (2.6 x 10(-4) M) does not inactivate the enzyme. After inactivation with 2-bromo[2' 14C]acetamidoestrone methyl ether, amino acid analysis reveals carboxymethylated derivatives of cysteine, histidine, and lysine containing 65, 25, and 8%, respectively, of the total incorporated carboxymethyl groups. The presence of estradiol, NADP+, or NADPH clearly inhibits alkylation of cysteinyl and histidyl residues and slows the rate of enzyme inactivation. Protection of these residues by both estradiol and NADPH suggests that they may actually be in the cofactor region of the active site, that this region is close to the steroid A-ring, and that binding of cofactor, by physical interposition, denies the reagent-bearing steroid access to these residues. PMID- 6928852 TI - Bone destruction in myelogenous marrow crisis. AB - Sudden appearance of bone destruction in chronic myelogenous leukemia may herald a blastic bone marrow crisis. PMID- 6928851 TI - Local recurrence after amputation for osteosarcoma. AB - Two hundred and forty-eight high-grade central osteosarcomata were treated by amputation or disarticulation; in 5.2 per cent the tumour recurred at the amputation site. The following causes may be responsible for local recurrence: the level of the amputation is too close to the tumour; there is an unrecognised intramedullary extension of the tumour; during a previous block resection tumour cells may have been seeded in the soft tissues; the primary tumour was too extensive even for radical surgery; "skip" metastases may have been present; iatrogenic tumour implantation may have occurred while a biopsy was being performed during the course of an amputation. Treatment of the primary osteosarcoma should take all these possibilities into account. In our experience adjuvant chemotherapy has not significantly changed the frequency of local recurrences which should be treated by radical operation or, if this is not possible, by irradiation; chemotherapy may be used as an adjuvant. The prognosis of local recurrences is bad. PMID- 6928853 TI - Multiple pulmonary nodules in leukemia. AB - A patient with acute myelogenous leukemia, in clinical remission following chemotherapy, presented with three unusual pulmonary nodules. Needle biopsy showed that these were leukemic cells in the interstitium of the lung. PMID- 6928854 TI - Sex and acid phosphatase in childhood non-T lymphoblastic leukaemia. AB - A semiquantitative assessment of blast cell acid phosphatase activity, expressed as a score, was made in 41 unselected children with newly diagnosed and untreated non-T acute lymphoblastic leukaemia (ALL). Despite a wide range of enzyme activity in both sexes boys had significantly higher scores than girls, and, in view of the known association between males and T ALL on the one hand, and between acid phosphatase and T ALL on the other, these findings raise the possibility that boys may have a predisposition to a type of pre-T ALL which could contribute to the as yet unexplained difference in prognosis between the sexes. PMID- 6928855 TI - Histological evaluation of probing depth following periodontal treatment. AB - The aim of this study was to compare the periodontal probing depth in teeth exposed to periodontal treatment with teeth having received no treatment. In pockets deeper than 4 mm, a significant difference was found between the two groups. In the non-treated teeth, metal strips used for probing penetrated an average of 0.29 mm into the connective tissue apical to the junctional epithelium. The average probing depth for teeth exposed to scaling, root planing, curettage and chlorhexidine rinses for 1 month was 0.31 mm coronal of the connective tissue attachment within the junctional epithelium. The results indicate that care should be taken when evaluating changes in periodental probing measurements during longitudinal studies. PMID- 6928856 TI - Juvenile periodontitis. Some microbiological, histopathological and clinical characteristics. AB - The microflora of periodontal pockets and some histopathological characteristics of adjacent tissues from individuals with clinical signs of juvenile periodontitis were studied. Adult individuals with ordinary, rapidly advancing periodontitis served as controls. All of the patients had been referred for specialist treatment. Using criteria defined by Baer (19z1), the patients were assigned to one juvenile periodontitis (eight patients), one post-juvenile periodontitis (seven patients) and one adult periodontitis group (seven patients). Only lesions around the first molars and central incisors were studied. Bacterial samples were obtained from each site and were examined by darkfield microscopy and different morphological forms identified. The soft tissue of the diseased sites was excised. The biopsies were placed in a fixative, cut in 1-mm-thick blocks and embedded in Epon. In semithin sections the infiltrated connective tissue (ICT) was identified and the ICT portion further processed for electron microscopy. The numeric and volumetric densities of different cells and structures of the ICT were determined using a morphometric point-counting procedure. The results showed that juvenile periodontitis lesions are associated with a subgingival microflora, the composition of which is different from that of adult periodontitis. Thus, in patients belonging to the adult periodontitis and post-juvenile periodontitis groups, motile microorganisms dominated the subgingival plaque samples, whereas deep pockets in juvenile periodontitis lesions contained a flora dominated by coccoid cells and straight non-motile rods. The most pronounced difference in the composition of ICT between the juvenile on one hand and the post-juvenile and adult periodontitis lesions on the other, was related to the amount of extracellular structures. Thus, in post juvenile and adult periodontitis lesions, collagen and residual tissue made up around 50% of the infiltrate. In the juvenile periodontitis lesions, however, extracellular structures occupied only around 20% of the volume. In the ICT of the juvenile periodontitis sites, around 70% of the volume was occupied by plasma cells and blast cells. The corresponding figures for the post-juvenile and adult periodontitis sites were 50 and 30%. PMID- 6928857 TI - Cutaneous manifestations of disseminated candidiasis. AB - Recognition of the characteristic cutaneous lesions of disseminated candidiasis may allow earlier diagnosis and treatment of this often fatal fungal infection. The skin lesion developed in patients with hematologic malignancies and compromised host defenses, at a time when they were febrile, clinically deteriorating, and failing to respond to multiple antibiotics. This report discusses two patients with acute myelogenous leukemia with cutaneous manifestations of disseminated candidiasis due to Candida tropicalis. Single or multiple erythematous or purpuric 0.5- to 1-cm papulonodules with pale centers were seen on the trunk and proximal extremities. In most reported cases of disseminated candidiasis with skin lesions, the diagnosis can be confirmed by histologic evaluation of a skin biopsy before appropriate cultures identify the organism. PMID- 6928858 TI - Prolonged nursing habit: a profile of patients and their families. AB - No association of the prolonged nursing-habit with the family background was found with the exception of predominantly lower socioeconomic conditions. All subjects demonstrated prolonged bottle-feeding or breast-feeding. Milk was reported to be the liquid most often used in the bottle. Parents reported that they did not know when weaning should occur, and when oral hygiene should be instituted. The nearly symmetrical caries pattern, the teeth most often affected and the order in which they are attacked and destroyed are conditions which are similar to those described in earlier studies. PMID- 6928859 TI - The relative effects of three dietary supplements on dental caries. PMID- 6928860 TI - Treatment of a talon-cusp incisor: report of case. PMID- 6928861 TI - Dental care. PMID- 6928862 TI - From the president. PMID- 6928863 TI - Prices, purists, and prevention. PMID- 6928864 TI - Inflammatory follicular cysts. PMID- 6928865 TI - Scanning electron microscopic and radiographic correlation of articular surface and supporting bone of the mandibular condyle. AB - Specimens of mandibular condyle from human cadavers were employed for scanning electron microscopic and radiographic observations of the articulating surface and underlying bone. Smooth articular surface supported by smooth bone was most frequently observed. Craters and depressions in the articular surface were associated with resorption of underlying bone. Lateral radiographs proved to be of limited value in detecting defects of this type. PMID- 6928867 TI - Systemic absorption of fluoride from alginate impression material in humans. AB - Thirty minutes after routine alginate impressions in five adult subjects, plasma fluoride levels increased by an average of 2.6 times over control values. Urinary fluoride excretion rates increased approximately 2.9 times during the first two hours after the impressions. Average whole saliva fluoride levels at 15 minutes were over 100 times the average control concentration. When small amounts of alginate were deliberately ingested, plasma fluoride levels and urinary excretion rates increased sharply. PMID- 6928866 TI - Estimated fluoride intake of average two-year-old children in four dietary regions of the United States. AB - Analysis of toddler "Market Basket" food collections indicates that an average two-year-old child living in cities with water supplies containing 0.37 to 1.04 ppm of fluoride has a daily fluoride intake of 0.315 to 0.610 mg/day (0.025 to 0.049 mg/kg body weight) from food, water, and beverages. PMID- 6928868 TI - A comparison of interests of first year dental students and fellows of the Academy of General Dentistry on the Strong-Campbell Interest Inventory. AB - The SCII was used to evaluate the similarity of interests of a sample of practicing dentists and those interests of a sample of dental students. The two groups were found to have similar interest patterns, except for business and office considerations. While the SCII's specific vocation scale for dentistry did not yield very strong positive results in terms of identifying the dental students, it did reveal useful interest patterns. As a general instrument for self-assessment, or for counselors advising the young about a vocation in dentistry, the SCII has some utility if the pattern of interests is used. PMID- 6928869 TI - The oscillating rheometer--what does it measure? AB - The motion involved in the operation of an oscillating rheometer was analyzed, and revealed that the instrument measured a complex mixture of an instrument dependent parameter, the spring constant, and two material-dependent parameters- the dynamic viscosity and the shear storage modulus. The significance of the working and setting time parameters measured by the rheometer are discussed. PMID- 6928870 TI - Factors affecting the depth of cure of UV-polymerized composites. AB - Knoop hardness measurements of UV-polymerized dental composites showed that, at a certain depth below the surface, the degree of cure rapidly decreases. The depth of cure was found to be critically dependent on the UV source and exposure time used. A theoretical model was derived which was in quantitative accord with the results. PMID- 6928871 TI - Erosion of composite resins. AB - The surface degradation of composite resins caused by accelerated aging was studied. Accelerated aging for 900 hours caused erosion of the resin matrices and exposure of filler particles. Differences in surface profiles after aging suggest that the materials eroded at different rates. Accelerated aging may model erosive wear of composites. PMID- 6928872 TI - Sn4(OH)6Cl2 and SnO corrosion products of amalgams. AB - Although the corrosion characteristics of dental amalgam have been of considerable interest to dental researchers, it has been difficult to identify the products which form in vivo. This report demonstrates that Sn4(OH)6Cl2 and SnO are formed in vivo and in vitro. The Sn-Cl product is the predominant phase formed by corrosion-induced changes of the Sn8Hg phase of amalgam. It is present in conventional and, in smaller amounts, Cu-rich amalgam restorations. PMID- 6928874 TI - Influence of combinations of oat hulls and sodium trimetaphosphate upon dental caries in the rat. AB - Two rat caries studies were conducted in which oat hulls, sodium trimetaphosphate, and combinations thereof were incorporated into two different caries-producing diets. The type of diet used was found to influence the anti caries effects of oat hulls. In many instances, the cariostatic effect of the two agents was additive or even synergistic. PMID- 6928873 TI - The relationship between the expression of the epithelial blood-group substances and malignancy: a preliminary report. PMID- 6928875 TI - Predicting alveolar bone loss in beagles using bone-seeking radiopharmaceutical uptake. AB - Measurements of bone-seeking radiopharmaceutical uptake obtained at the beginning of this two-year study of beagles with periodontal disease were correlated with the amount of bone loss which occurred during the study. Uptake correlated with bone loss (r = 85), which suggests that uptake may be an indicator of future bone loss. PMID- 6928876 TI - Dental manpower supply and requirements: the effect of national estimates on individual dental schools. PMID- 6928877 TI - Activities by the schools to improve the distribution of dentists: an AADS report. AB - It appears that most dental schools have not yet become actively involved in efforts to solve maldistribution problems. However, there seems to be increasing interest in the potential benefits of extramural experience programs. Coordination of efforts by the schools, the state dental associations, and the state boards of dental examiners is very limited, but is clearly needed. Admissions committees seem to be trying to take into account the needs of rural areas and the inner city as well. Finally, the results of the survey point up the need for further study of these problems and of the value of particular approaches to them. PMID- 6928878 TI - Curriculum considerations for correlating basic and clinical sciences. AB - An analysis of the problem of curriculum design for correlating basic and clinical sciences is presented. The analysis identifies six ways a dentist can profit from the basic sciences: (1) increased sensitivity to the environment, (2) improved judgement, (3) better explanations to patients, (4) enhanced ability to learn, (5) improved communication with health professionals, and (6) greater role diversity. Literature is reviewed related to four mental processes underlying functional knowledge: attending, associating with past learning, relation to future situations, and practicing mental applications. Implications are made for the design of dental curricula and instructional techniques based on factors that influence the recall and use of knowledge. PMID- 6928879 TI - Computer-based management of a clinical teaching program. AB - A management system is described that uses a computer to assist in the matching of patients and dental students, the monitoring of patient care, and the tracking of student clinical progress in a teaching environment that emphasizes the comprehensive patient care approach. PMID- 6928880 TI - An application of interpersonal process recall for teaching behavioral sciences in dentistry. PMID- 6928883 TI - AADS special report. Curricular guidelines for comprehensive control of pain and anxiety in dentistry. PMID- 6928881 TI - Nonresponse bias to mail survey questionnaires within a professional population. AB - Mail survey questionnaires are often used in dental research. In most instances, results depend on a single mailing and an incomplete return rate. The possible bias resulting from excluding nonresponders in tabuling data from mail survey questionnaires in a dentist population was investigated. Two different questionnaires, one soliciting attitudes, the other knowledge, were sent to randomly selected dentists. The differences between the responders and the nonresponders were analyzed with respect to the dentists' demographic data, attitudes, and knowledge. It was concluded that: (1) subject matter does affect dentist response rates to mailed survey questionnaires, (2) there are no differences in demographic data between dentist responders and nonresponders, and (3) nonresponse bias does not affect the results of dental surveys on a typical dentist response rate. PMID- 6928882 TI - Interpretation and use of the dental admission and aptitude tests. AB - Despite the fact that all dental school applicants in Canada are required to take the Dental Aptitude Test (DAT) and their counterparts in the United States take the Dental Admission Test (DAT), there is an apparent lack of understanding in the translation and application of the information provided by the test. A review of the literature might assist admissions committee members in interpreting DAT results and in making more sound decisions in selecting students, To put the information into perspective, a brief overview of the history of the DAT, its composition, underlying concepts, and the problems of validation and guidelines for its use are presented. PMID- 6928884 TI - Dental student profile system. PMID- 6928885 TI - Update or out-of-date? PMID- 6928886 TI - Local anesthetic. PMID- 6928887 TI - Service to retired dentists. PMID- 6928888 TI - The price of apathy. PMID- 6928889 TI - Myofascial pain. PMID- 6928890 TI - Dental education and the British National Health Service. PMID- 6928893 TI - Consumer perceptions of dental care in the health services program of an educational institution. AB - A consumer survey was used to evaluate the University of Massachusetts dental service, a program emphasizing an educational and preventive approach, comprehensive care, and consideration of some prepayment. Attitude and courtesy of staff, explanation of treatment, and the educational approach of the services were favorably assessed by the patients. Those who attended the dental education sessions reported higher levels of satisfaction with the service than those who did not. Mechanisms for financing and the philosophical emphasis on health education seem to have resulted in an extremely successful service. PMID- 6928891 TI - Economics of electrolytic recovery of silver from radiographic fixing solutions. PMID- 6928892 TI - Preventive resin restorations: three-year results. PMID- 6928894 TI - Supervised weekly rinsing with a 0.2% neutral NaF solution: results from a demonstration program after three school years. AB - A school-based fluoride rinsing program was instituted in 1975 in the Three Village Central School District, Long Island, NY. The children rinsed once a week with a 0.2% neutral NaF solution under supervision of the homeroom teachers. After three years, the participants had rinsed an average of 77 times. Children in grades 3 through 7 who had participated during all three years of rinsing had a reduction in caries prevalence of 30.9% for DMFS and 28.5% for DMFT. The greatest reduction occurred on proximal surfaces (48.7%), followed by buccolingual surfaces (30.0%) and occlusal surfaces (28.2%). The benefits of fluoride rinsing increased with the duration of the program. PMID- 6928895 TI - Systemic lupus erythematosus. AB - A case of osteomyelitis of the mandible in a patient with systemic lupus erythematosus is described. Both the disease process and the treatment modalities must be understood for correct management. PMID- 6928897 TI - Oral fibrolipoma beneath complete mandibular denture. AB - A case of an oral fibrolipoma located beneath a mandibular complete denture in a 65-year-old white woman has been presented. The soft, freely movable, yellow encapsulated mass, covered by thin epithelium with a vascular pattern, measured 15 mm in diameter. The fibrolipoma appeared radiographically as a radiolucent area above the left mandibular ridge. The patient's history disclosed no symptoms of pain, bleeding, or discomfort caused by the mass under the denture. A concave area in the mandibular denture corresponding to the location of the tumor indicated that the previous denture was made over the existing tumor. The mass was excised. Histopathologic examination disclosed benign epithelium overlying adipose tissue divided by connective tissue. The diagnosis was benign fibrolipoma. The healing process was uncomplicated. New dentures were made after healing was complete. There has been no evidence of recurrence. PMID- 6928896 TI - Ankylosis of maxillary permanent first molar. AB - A case of ankylosis of the maxillary right first permanent molar has been described. For 19 months, no change had been observed clinically or radiographically in the development of the tooth. A diagnosis of ankylosis of the unerupted tooth was made. Instead of extracting the tooth, the ankylosed tooth was rocked in the bone to break the point of ankylosis. The tooth subsequently erupted and satisfactory functional results were obtained. It is suggested that this procedure should be attempted in other cases of ankylosis of permanent teeth. PMID- 6928898 TI - The keratinizing and calcifying odontogenic cyst (Gorlin cyst). AB - A 61-year-old white woman had a radiolucent lesion in the anterior portion of the mandible which was diagnosed as a keratinizing and calcifying odontogenic cyst. As it has a radiographic appearance similar to other pathologic processes, it should be considered in the differential diagnosis when a radiolucent-radiopaque lesion is encountered. PMID- 6928899 TI - A radiographic technique for maxillary third molars. AB - To obtain an accurate radiographic image of the maxillary third molars with roots and without the superimposition of the zygomatic arch is sometimes difficult. A simple, fast, and effective technique to obtain such an image is described. The technique could be useful also in the practice for handicapped patients as it requires little cooperation from the patient. PMID- 6928900 TI - NIDR develops intraoral system for controlled fluoride release. PMID- 6928901 TI - Matters of dissent. PMID- 6928902 TI - Dental care of refugees. PMID- 6928903 TI - Arthrography of the TMJ. PMID- 6928904 TI - Low-level radiation risk. PMID- 6928905 TI - Back to anesthesia. PMID- 6928906 TI - The New Zealand system. PMID- 6928907 TI - No longer outsiders. PMID- 6928908 TI - The case against intentional replantation. PMID- 6928909 TI - Reports of pain after dental treatment, electrical tooth pulp stimulation, and cutaneous shock. AB - A growing body of literature suggests that pain is a crucial factor in the development and maintenance of apprehension toward dental treatment. These findings are often at variance with dental practitioners' impressions that routine dental treatment is virtually painless. Data from this study suggest that routine dental treatment is seldom perceived by regular patients as painless but is seen as low in intensity of pain compared with mild laboratory stressors. These data are interpreted as supporting the hypothesis that dental treatment is relatively painless. However, this conclusion conflicts with data supporting the importance of pain in dental fear, and possible reasons for the discrepancy are presented. PMID- 6928910 TI - Intramuscular sedation technique. AB - A sedative technique with meperidine hydrochloride and promethazine hydrochloride via an intramuscular injection is presented. We believe this is an excellent technique because of the safety to the patient and the ease of administration. Like any technique using potentially dangerous medications, practitioners and their staff must be familiar with and prepared for possible complications. When the technique is mastered, it will be a valuable addition for treatment of certain mentally and physically handicapped patients. PMID- 6928911 TI - Atypical calcifying epithelial odontogenic tumor of the maxilla. AB - A case of atypical calcifying epithelial odontogenic tumor is reported to show that many different lesions can cause periapical radiolucent areas and to contribute to the expanding histologic spectrum of the calcifying epithelial odontogenic tumor. Methods used in differential diagnosis of radiolucent lesions in the jaws include: comprehensive history, clinical and radiographic examination, tooth vitality tests, laboratory tests, aspiration, and biopsy. To prevent hemorrhage, precautions should be taken before biopsy or surgery to rule out a vascular lesion. Proper treatment of odontogenic tumors requires thorough removal of the tumor for initial therapy and close, long-term, follow-up observation to check for recurrence. PMID- 6928912 TI - Transposition of canines. AB - Eleven cases of canine transposition, in both the maxillary and the mandibular arches, have been reported. Canines were involved in every case. Alignment of the teeth in their transposed position or orthodontic movement to their normal position in the arch are alternatives in treatment. However, should an involved tooth be seriously affected by caries, developmental defects, or trauma, extraction may be the preferred treatment, with alignment of the remaining tooth and closure of the space. PMID- 6928914 TI - Dedicate $16 million San Francisco dental school building. PMID- 6928913 TI - Epithelial melanosis of the gingiva possibly resulting from the use of oral contraceptives. AB - This case is typical of others we have seen. All cases have been those of female patients who were taking oral contraceptives. A relationship is suggested between use of oral contraceptives and gingival melanosis in individuals with light complexions. It would be appropriate, therefore, to question such patients about the use of oral contraceptives and to consider this relationship in a differential diagnosis. PMID- 6928915 TI - GAO finds panacea for dental system woes--or, stop me if you've heard this one. PMID- 6928916 TI - Quality. PMID- 6928917 TI - Turnabout: the FTC under siege. PMID- 6928918 TI - Edema-horn, an abnormal mutant of Biomphalaria glabrata. PMID- 6928919 TI - [Whole lung computed tomography for detection of pulmonary metastasis of osteosarcoma confirmed at thoracotomy (author's transl)]. PMID- 6928920 TI - The single parent. PMID- 6928921 TI - Humanistic nursing in a technological society. PMID- 6928922 TI - Humanistic nursing: case study of a long term patient. PMID- 6928923 TI - Humanistic nursing: case study of an acute care patient. PMID- 6928924 TI - Learning/teaching styles: cognitive mapping. PMID- 6928926 TI - Problems of single-parent families. PMID- 6928925 TI - Teaching/learning styles: cognitive mapping the experience of one nurse education program. PMID- 6928927 TI - Accepting the challenge of change. PMID- 6928928 TI - Modified extraskeletal fixation appliance. PMID- 6928929 TI - Board to death. PMID- 6928930 TI - Management of the nasal apparatus in maxillary surgery. AB - Many patients requiring maxillary surgery for the correction of dentofacial deformities have pre-existing nasal airway obstructions. In addition, some of the movements accomplished during surgery may reduce the volume of the nasal cavity or may result in nasal airway obstructions. Techniques for eliminating pre existing nasal obstructions and of avoiding adverse effects on the nasal airway resistance after maxillary surgery are presented. PMID- 6928931 TI - The maxillary ameloblastoma: an analysis of 24 cases. AB - Twenty-four cases of maxillary ameloblastoma from the files of the dental and oral division of the Armed Forces Institute of Pathology and the US Army Institute of Dental Research were reviewed. Clinical findings showed an average age of 45.6 years, a male-to-female ratio of 2.4:1, and an equal racial distribution between whites and blacks. Eighty-eight percent of the tumors occurred distal to the maxillary canine. A slowly enlarging mass was the primary clinical sign in more than 90% of the cases. Recurrences were seen in eight of the 16 cases on which follow-up information was received. The majority of the tumors had a mixed follicular histologic pattern. Therapy should consist of either surgical block excision or hemimaxillectomy. The surgeon must carefully weigh the potential danger of the neoplasm against the deformity and disability caused by the surgical procedure. PMID- 6928932 TI - Hearing sensitivity and measurements of middle ear and eustachian tube function after maxillary osteotomy with advancement surgery. AB - The nature of audiologic changes after maxillary osteotomy with advancement surgery has not been fully documented. The purpose of this investigation was to better understand the potential alteration of eustachian tube, middle ear pressure and static compliance, and hearing sensitivity in individuals undergoing this type of surgical procedure. Pure tone audiometry and evaluation of middle ear and eustachian tube function were done on seven patients preoperatively and at the 3rd, 6th, and 12th postoperative weeks. Results indicated that, although hearing sensitivity and middle ear and eustachian tube function change from the normal preoperative state during the early postoperative recovery period, they return to normal limits by the 12th postoperative week. These changes suggest the importance of carefully audiologic status in patients undergoing this type of procedure. PMID- 6928933 TI - The effects of glossectomy on intelligibility of speech and oral perceptual discrimination. AB - The effects on the intelligibility of speech and oral perceptual ability after glossectomy were studied in 20 patients. The intelligibility, rate of speech, and oral form discrimination ability were measured as they varied by the extent of surgical ablation. The results indicated that speech and oral discrimination ability are more severly impaired in patients who undergo more extensive surgical excision. The rate of speech of most of the patients was slower than normal. The results were interpreted to reflect the value of residual oral tissue. The amount of lingual and adjacent tissue to be excised may be regarded as a rough index of the effect such surgery will have on oral communication. PMID- 6928934 TI - Pediatric fractures of the facial skeleton: a survey of 85 cases from Kaduna, Nigeria. AB - A survey of 1,447 cases of fractures of the facial skeleton from Kaduna, Nigeria, showed that 85 cases (5.9%) occurred in children younger than 13 years. The lowest incidence recorded was in the group of patients younger than age 3 but there was a gradual increase up to the age of 13 years, with the highest incidence occurring in the 12- to 13-year-old age group. The male-to-female ratio was 2.1 to 1. The site distribution in descending order of frequency was body of the mandible, mandibular condylar process, angle of the mandible, malar and nasal complexes, maxilla, and ascending ramus of the mandible. Most of the fractures were immobilized by simple methods, and union was achieved within two to six weeks. Of the 12 fractures of the condylar process, ankylosis of the temporomandibular joint developed in six; in addition, two had mandibular undergrowth. PMID- 6928935 TI - Medical palatine cyst and maxillary antral osteoma: report of an unusal case. AB - A case is presented of a patient with the coincidental occurrence of two unusual lesions, median palatine cyst and osteoma of the maxillary antrum. There was no atypia of either lesion, but this combination led to the impression that the median palatine cyst had eroded into the maxillary antrum. Both lesions are usually asymptomatic and were incidental findings in this case. An occlusal radiograph is best for showing the palatal radiolucent area and is usually diagnostic. The preferred treatment for median palatine cyst is enucleation; a palatal splint is an excellent aid for reapproximation of the mucoperiosteal flap. The maxillary antrum was explored to obtain a biopsy specimen for a microscopic diagnosis of the radiopaque lesion; this proved to be an osteoma. The diagnosis of an osteoma is an indication for a radiographic survey to rule out Gardner syndrome, which has serious implications. PMID- 6928936 TI - Unilateral atrophy of the mandibular condyle after closed subcondylar osteotony for correction of mandibular prognathism. AB - A case of unilateral atrophy of the mandibular condyle after bilateral closed subcondylar osteotomies for the correction of mandibular prognathism has been presented. Some of the possible causes have been discussed. PMID- 6928937 TI - Solitary subcutaneous lipoma: report of case. AB - A submental lipoma in a 66-year-old black man is presented. The etiology of the lesion is discussed and related to our case. The solitary subcutaneous lipoma is treated by excision. Recurrence is rare, and sarcomatous degeneration seldom occurs. Most other lesions of similar presentation and location occur in a younger age group than that of our patient. PMID- 6928938 TI - Squamous cell carcinoma of the mandible in Franconi anemia: report of case. PMID- 6928939 TI - Pulmonary metastasis from ameloblastoma of the mandible: report of case and review of the literature. PMID- 6928940 TI - Henoch-Schonlein purpura: report of case. AB - A case of Henoch-Schonlein purpura in a man has been presented. The patient was a typical candidate for the disease, with a history of major allergies and antecedent events of an upper respiratory infection and ingestion of at least two drugs previously implicated as etiologic agents. However, no specific allergen was identified and tests to verify it as an example of a circulating immune complex disease were not successful. The patient had many of the commonly found symptoms of HSP and additionally had the rare complications of both genital involvement and intraoral lesions. The disease ran its course in approximately eight weeks; there is little reason to believe that the patient will have a recurrence. PMID- 6928941 TI - Reiter syndrome: report of case. AB - Reiter syndrome is a triad of symptoms including urethritis, conjunctivitis, and arthritis. Frequently, mucocutaneous and oral lesions are present. A case has been presented and treatment discussed. PMID- 6928942 TI - Prolonged succinylcholine-induced apnea caused by atypical cholinesterase: report of case. AB - A case of prolonged apnea after administration of succinylcholine in a patient homozygous for the dibucain variant cholinesterase (genotype E1aE1a) has been presented. Knowledge of the patient's medical history, preoperative laboratory tests, and the length of apnea enabled the surgical team to eliminate liver disease, carcinoma, and malnutrition from the differential diagnosis. This, in addition to the patient's failure to respond to an anticholinesterase agent, led to the belief that the patient had an atypical cholinesterase response to succinylcholine and not one secondary to a decreased production of cholinesterase enzyme from an impaired liver or prolonged paralysis for the nondepolarizing agent, pancuronium. Treatment consisted of maintaining adequate pulmonary ventilation nitrous oxide sedation to diminish anxiety until the patient regained spontaneous respiration. Anticholinesterase agents were used after the patient had progressed to a phase II depolarization block. After a cholinesterase assay of the family's serum, all members having the atypical allele were instructed to obtain medical alert identification. PMID- 6928943 TI - Nosocomical Rhizopus infection (zygomycosis) in children. AB - Three children with the rare occurrence of zygomycosis are descibed: two had involvement of a solitary lesion of gangrenous cellulitis on the buttocks, and th third was a neonate with gastric performation and a gangrenous appendicitis. All three patients were compromised hosts (two with leukemia and one a premature infant with respiratory distress syndrome). All three patients appeared to have acquired the same organism. Rhizopus oryzae, from the same fomites, elastic bondages (Elastoplast). The Center for Disease Control has received several other reports of zygomycosis traceable to the same material. Alll three of our patients were cured of their infections. Early diagnosis and a combined surgical and chemotherapeutic approach appear to prevent death from zygomycosis. PMID- 6928944 TI - Comparison of the helminth faunas of two sympatric top carnivores from the rolling plains of Texas. PMID- 6928945 TI - Comparative ultrastructure of certain Actinomyces species, Arachnia, Bacterionema and Rothia. AB - A comparative ultrastructural study was carried out on several species of Acinomyces and related Gram-positive rods including Arachnia, Bacterionema, Rothia and Leptotrichia. A total of 52 well characterized strains were examined by transmission electron microscopy. Particular attention was paid to the ultrastructure of the cell periphery, that is the plasma membrane, periplasmic space, the cell wall per se and extramural structures, including surface "fuzz". In addition, the ultrastructure of various features of the cytoplasm were also examined. A good correlation appeared to exist between certain ultrastructural characteristics of the microorganisms and their taxonomic position as determined by other criteria. It should be noted, however, that the ultrastructure of certain strains differed markedly from that of the remaining strains of the species. This observation raises some doubt on the appropriateness of the current classification for these particular strains. The ultrastructural features of the cell periphery were found to be particularly stable for all strains grown under standard conditions. For this reason, ultrastructural features of the cell wall and associated structures are probably a more reliable source of morphological criteria for identification purposes than the ultrastructural characteristics of the cytoplasmic components which tend to be more variable. The results suggest that certain ultrastructural features are useful criteria for the identification and classification of these Gram-positive rods. PMID- 6928946 TI - Treatment of localized gingival recessions. Part IV. Results after three years. AB - Twenty-six localized recessions treated with either a lateral sliding flap or a coronally repositioned flap procedure more than 3 years ago were reevaluated. Biometric measurements on the recipient and the donor of control teeth included: a) cementoenamel junction, gingival margin; b) sulcus depth; c) gingival margin, mucogingival line. These recordings were statistically compared to those taken 180 days after the surgical procedures were performed. Pairwise t tests were used to determine whether there were any changes between the 180 days and the 3 years postoperative control with either procedure. A two sample t test was run to see whether the changes obtained with the two procedures differed from each other. No significant changes were found. The values for gingival recession, sulcus depth and width of keratinized gingiva remained stable for both techniques throughout the observation period. PMID- 6928947 TI - Presidential address. PMID- 6928948 TI - Osteopoietin-humoral induction factor in osteogenesis. AB - A heat-stable, glycoprotein-like material, osteopoietin, produced during bone marrow regeneration, has been shown to induce bone formation when implanted in the rat eye. The material was separated by ultrasonic treatment or by acid buffer (pH 3-5) from sponges implanted in the marrow. The extracted material free of bone or cell solids, induced bone formation in the anterior eye chamber of the rat, whereas the cell solids and control sponges similarly implanted did not. PMID- 6928949 TI - Familial benign chronic neutropenia associated with periodontal disease. A case report. AB - A rare case report of periodontal disease associated with familial benign chronic neutropenia is presented. The medical, dental and family histories as well as clinical and histologic observations are described and discussed. PMID- 6928951 TI - A new approach to vital root resection. AB - This report deals with ten cases in which periodontal surgery was performed followed by immediate resection of one of the vital buccal roots on maxillary molars. The resultant pulpal opening was treated with calcium hydroxide, zinc oxide and eugenol then sealed with an amalgam alloy. Two additional cases were treated in reverse order by first resecting the vital root followed by immediate periodontal surgery. All cases were evaluated over a 1 to 3 year period. The results indicate that vital root resection at the same time as periodontal surgery compares favorably with cases treated in which periodontal surgery was completed at a prior appointment. PMID- 6928952 TI - The use of a new topical hemostatic agent. AB - MICROFIBRILLARY COLLAGEN hemostat (MCH) is described in clinical use as a topical hemostatic agent for control of bleeding at the donor site of the free gingival graft procedures. On the basis of clinical trials, it is an excellent adjunct to periodontal surgical procedures. PMID- 6928953 TI - The value of repetition and reinforcement in improving oral hygiene performance. AB - The purpose of this study was to assess the value of including repetition and reinforcement in a dental health education program for school children. Sixty-one pupils, 11 to 13 years of age, were divided into three groups according to room assignments. Group I (control) received no oral hygiene lectures or instructions until the conclusion of the experiment. Group 2 (nonreinforced) received one lecture and a toothbrushing lesson, but no repetition or reinforcement. Group 3 (reinforced) received the same program as Group 2 on the initial visit and also received two additional visits for repetition and reinforcement of the lectures and instructions, plus a final summary lecture. Six visits were conducted at intervals of 0, 1, 5, 3, 8, 20 and 52 weeks, following a double-blind experimental format. PHP scores were obtained on all subjects on each of the six visits. It was concluded that the repetition and reinforcement components of this dental health education program were of significant value in improving the oral hygiene performance of the school children over a period of 1 year. The findings provide evidence of the desirability of incorporating these concepts in plaque control program. PMID- 6928950 TI - Clinical and laboratory studies on human sclera allografts. AB - In the first section of this two-part report human peripheral blood leukocytes were tested for reactivity to extracts of sclera. Absence of scleral antigenicity is suggested by the results which showed that the leukocytes reacted similarly in sclera stimulated cultures and in the controls. The second part of the report discusses the clinical aspects of sclera allografts and provides guidelines for their clinical use. A case is presented where a sclera graft was in position for approximately a year. The tooth was removed with the attached graft and a histologic study made. PMID- 6928954 TI - An analysis and clarification of the status of periodontosis as a disease entity. PMID- 6928955 TI - Clinical considerations for root-submergence procedures. PMID- 6928957 TI - Physical properties of a visible-light-cured composite resin. AB - This investigation has demonstrated some differences in physical properties between Fotofil and Adaptic. Clinically, these differences might be insignificant because the upper and lower limits of the values obtained for both were within the range for clinically acceptable composite resins as recorded in previous studies. PMID- 6928956 TI - Correction of anterior cross-bite using segmental osteotomies and a fixed splint. AB - A brief review of methods used in treating anterior crossbites has been outlined. Another approach was also presented using interdental segmental osteotomies to mobilize individual teeth and fixed splints to stabilize the realigned segments. The advantage of this treatment is the expedience with which final results can be obtained and the relative ease in accomplishing the surgical and prosthodontic procedures. PMID- 6928959 TI - Diminishing dependence on adhesives for retention of facial prostheses. AB - Attempts to augment or circumvent adhesives for retaining facial prostheses have been beneficial for many patients, particularly when a significant number of prostheses have failed because of insufficient retention. This approach is helpful in overcoming the problems created by the continued reluctance of surgeons to remove an entire facial organ in eradicating a relatively small disease process. There has been a positive response to suggestions that proposed surgery be planned to include the creation of sites which could be used for anatomic or mechanical retention. PMID- 6928958 TI - The ability of foods to stain two composite resins. AB - In this bench study, coffee and soy sauce stained composite resin restorations to a significantly greater degree than did tea or cola beverage. Generally, the greatest degree of staining with all samples occurred during the first week of the study time. The stain penetration was superficial and was estimated to be 5 mu or less. PMID- 6928961 TI - Explorations of the coping of adolescents with orofacial anomalies using the Cornell Medical Index. PMID- 6928960 TI - A resilient trnasparent custom maxillofacial surgical dressing. AB - A new modality in postsurgical wound care to improve the quality of life in the extraoral maxillofacial surgical oncology patient has been described. This approach to protecting wounds of the face has the potential of being used for almost any external part of the body. The dressing has the advantages of sterility, durability, transparency, versatility, conformability, resiliency, comfort, protection, and economy. Maxillofacial surgeons can utilize the many positive advantages of this new type of dressing which is available through the maxillofacial prosthodontist. PMID- 6928962 TI - Condylar remodeling after occlusal therapy. AB - Seven men and 15 women with TMJ pain dysfunction syndrome were selected. After clinical examination, polytomography of the TMJ was performed in centric occlusion in different planes. Open-mouth projections were also made in three patients, frontal tomography in one patient, and transcranial radiographs in 16 patients. Occlusal analysis was performed on the articulator. Twenty patients showed various patterns of condylar displacement with flattening of the anterior, superior, or posterior condylar walls in 11 patients, including three with arthritic lesions. Therapy included occlusal splints (21 patients), selective grinding (seven patients), prosthodontic rehabilitation (10 patients), and orthodontic treatment (two patients). After therapy, tomographic examination was repeated at intervals of 9 to 44 months. A distinct reshaping of the condyle was seen in seven patients. The new shape tended to be rounded. The three patients with degenerative changes before treatment showed regression of the lesions. No change was seen in condyles which were rounded before therapy. PMID- 6928965 TI - Meeting the challenges facing prosthodontics. PMID- 6928964 TI - Mercury levels in dental students and faculty measured by neutron activation analysis. AB - Samples of head hair, fingernails, and toenails were taken from 61 dental students and faculty members. The mercury levels were analyzed using a simple neutron activation analysis technique which proved to be easily applicable to large numbers. Significant results were found for the head hair and fingernail groups. There may be a correlation between the higher mercury levels and increased pressure of work, which might result in decreased standards of mercury hygiene. PMID- 6928963 TI - Effect of occlusal splints on the electromyographic activities of masseter muscles during maximum clenching in patients with myofascial pain-dysfunction syndrome. AB - Integrated EMG activities of masseter muscles during maximum voluntary isometric contraction with and without full-arch maxillary stabilization splints were observed in patients with MPD syndrome having occlusal interferences and in healthy subjects having no occlusal interferences. The masseter muscle activity was more significantly reduced in patients with MPD syndrome during maximum clenching with splints than in those patients without splints. In healthy subjects, such a significant difference could not be observed with and without splints. This finding suggests that the elimination of the occlusal interferences by means of occlusal splints could reduce the degree of sensory information from the periodontal receptors during nocturnal clenching or grinding. This could result in a decrease in masseter muscle activity giving rise to muscular relaxation. PMID- 6928966 TI - Precision technique for trimming dies using a magnification device. AB - This article described a technique for trimming a die under magnification. However, the microscope is also useful for checking (1) margins of wax patterns for completeness, (2) the internal surfaces of castings for imperfections, bubbles, or retained investment particles which could prevent proper seating of the castings on the dies, (3) for cracks or contamination in dental porcelain as well as porcelain flash on margins; and (4) precision attachment operation after casting or soldering procedures. Attention to detail in these laboratory procedures greatly improves the final fit of dental castings and saves subsequent chairside adjustments and remakes. PMID- 6928967 TI - Synthesis and antitumor activity of 2,4-diamino-6-(2,5-dimethoxybenzyl)-5 methylpyrido[2,3-d]pyrimidine. AB - The synthesis of 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3 d]pyrimidine (BW301U, 7) by a route that has general applicability to the preparation of many 6-(substituted benzyl)-5-methylpyrido[2,3-d]pyrimidines is described. The key intermediate, 2,4-diamino-7,8-dihydro-6-(2,5-dimethoxybenzyl) 5-methyl-7-oxopyrido[2,3-d]pyrimidine (4), is converted to the 7-chloro compound 5 by treatment with a 1:1 complex of N,N-dimethylformamide--thionyl chloride, and 5 is hydrogenolyzed with palladium on charcoal in the presence of potassium hydroxide to yield 7. BW301U is a potent lipid-soluble inhibitor of mammalian dihydrofolate reductase and has significant activity against the Walker 256 carcinosarcoma in rats. PMID- 6928968 TI - Drinking and pregnancy. PMID- 6928969 TI - Indications for endoscopic retrograde cholangiopancreatography (ERCP). PMID- 6928972 TI - Infectious hepatitis and the Guillain-Barre syndrome. PMID- 6928971 TI - Solitary neurofibroma of rib. PMID- 6928970 TI - Pericardial tamponade in rheumatoid arthritis. PMID- 6928973 TI - "Chronic" dermatomyositis: response to corticosteroids. PMID- 6928974 TI - The electrocardiogram. Nonparoxysmal junctional tachycardia. PMID- 6928975 TI - Lactase deficiency. PMID- 6928976 TI - Your Congressman speaks. Cambodia. PMID- 6928977 TI - Technology assessment. PMID- 6928978 TI - Perforation of the gallbladder: analysis of 22 cases. PMID- 6928981 TI - Management of respiratory failure. PMID- 6928983 TI - Controlled prophylactic trials in cancer. PMID- 6928982 TI - Multiple forms of 17 beta-hydroxysteroid dehydrogenase in the soluble fraction of the guinea pig liver and kidney. PMID- 6928979 TI - Composite stepwise mutation model under the neutral mutation hypothesis. AB - As an extension of the conventional ("Ohta-Kimura") stepwise mutation model, a new model is proposed. In this model, it is assumed that each charge state ("electromorph") is represented by K alleles and that a mutation changes an allele either by one step in the charge space or to one of the other members of the identical electromorph. It is shown that the net genetic variability within a population is similar to that predicted by the infinite-allele model ("Kimura Crow" model) rather than to that predicted by the stepwise mutation model, and the K-dependence of genetic variability is rather weak when K greater than or equal to 2 and the effective population size is not much greater than the reciprocal of mutation rate. The results are compared with the recent observations at the xanthine dehydrogenase locus in Drosophila pseudoobscura. PMID- 6928980 TI - Spontaneous regression of Friend virus-induced erythroleukemia. VI. Structural and antigenic differences between the regressing and conventional strains of virus. AB - The regressing and conventional strains of Friend virus were compared by neutralization assays, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and tryptic peptide mapping of the individual viral components. Neutralization rates of the two viruses differed in the presence of monospecific anti-gp70 antiserum and sera from regressed or immunized mice. Neutralization of regressing Friend virus, but not conventional Friend virus, occurred when the viruses were incubated with anti-p15(E) and complement. Human serum inactivated conventional Friend virus more rapidly than regressing Friend virus, probably as a result of virolysis induced by the reaction of viral p15(E) with human complement component C1. Structural differences between the viruses were detected in their gp70 viral glycoproteins and p15(E) and p12 proteins. Analysis of different stocks and clonal isolates of the viruses showed that the differences between the gp70 and p15(E), but not the p12 proteins, were associated with the regressing phenotype of the regressing strain of Friend virus. PMID- 6928984 TI - Tobacco use, occupation, coffee, various nutrients, and bladder cancer. AB - In a Canadian population-based case-control study of 480 males and 152 female case-control pairs, the relative risk for development of bladder cancer for ever used versus never used cigarettes was 3.9 for males and 2.4 for females, with a dose-response relationship in both sexes. A reduced risk was associated with the use of filter cigarettes compared to nonfilter cigarettes. After control for cigarette usage, a significant risk was noted for male pipe smokers. For male ex smokers the risk after 15 years of no smoking was less than one-half that of current male smokers. Bladder cancer risk was found for workers in the chemical, rubber, photographic, petroleum, medical, and food processing industries among males and for workers occupationally exposed to dust or fumes among both sexes. Bladder cancer risk was elevated for males consuming all types of coffee, regular coffee, and instant coffee and for females consuming instant coffee, but no dose response relationship was found. Risk was found for males consuming water from nonpublic supples but not for females. No risk was observed in males or females consuming nitrate-containing foods, beverages other than coffee, or fiddlehead greens. Hair dye usage in females and phenacetin usage in males and females carried no risk. Divergent findings by area for aspirin suggested that an overall association was not causal. Reevaluation of the data on artificial sweeteners confirmed a significant bladder cancer risk in males and a dose-response relationship. The cumulated population attributable risk for bladder cancer was 90% for males from cigarette smoking, industrial exposure, and exposure to nonpublic water supplies and 29% for females from cigarette smoking, industrial exposure, and instant coffee consumption. PMID- 6928985 TI - Liposome-encapsulated methotrexate interactions with human chronic lymphocytic leukemia cells. AB - The uptake of free and liposome-entrapped methotrexate (MTX) by human chronic lymphocytic leukemia cells was compared under incubation conditions resembling those encountered in vivo. Liposome encapsulation enhanced up to 200 times the association of MTX with these cells. Autoradiographic studies established an association of [3H]MTX liposomes with the cells. Such a mode of delivery did not significantly increase the amount of drug available to inhibit dihydrotolate dehydrogenase, which suggested that the liposome content was not readily available to the cytoplasmic sites of action. Increased doses of encapsulated MTX resulted in enzyme inhibitions that were similar to those obtained with the free drug. This finding demonstrates that higher doses of MTX delivered by liposomes could be potentially useful in overcoming drug-transport resistance. PMID- 6928987 TI - Thirty-four lines of six human tumor categories established in nude mice. PMID- 6928986 TI - Cancer mortality in a cohort of naval shipyard workers in Hawaii: early findings. AB - A retrospective cohort study was performed in Hawaii among 4,779 male shipyard workers exposed to asbestos and 2,757 similar male workers without known asbestos exposure. Observed deaths from cancer and other causes in the 2 groups were compared with expected deaths on the basis of the general population of Hawaii by the use of a modified life-table method of analysis. A risk ratio for lung cancer of 1.7 was found for the exposed group after 20 or more years of follow-up. No increased risk for lung cancer was seen in the nonexposed group. These findings could not be attributed to differences in smoking habits in the 2 shipyard groups or between the shipyard groups and the general population. Because the maximum duration of follow-up for this analysis was 24 years, greater risks for lung cancer may be seen in the exposed group when the follow-up period is extended. PMID- 6928988 TI - Socioeconomic status, urine estrogens, and breast cancer risk. AB - Urine estrogens were measured in 46 women students, ages 15-18, at a middle-class high school in Athens and in 40 women of the same age residing at one of three orphanages in the same city. The lower socioeconomic status (SES) of the latter group was documented by their lower mean height (by 5.2 cm) and weight (by 5.3 kg) relative to the high school students. Both in follicular and luteal phases of the menstrual cycle, the women with lower SES had 50% higher estriol ratios (ratio of the concentration of estriol to the sum of the concentrations of estrone and estradiol). In luteal specimens the concentration of all three major estrogens was higher in the group with low SES than in the women in the other group, but the concentration of estriol was most increased. There was also an indication of less frequent anovular cycles among the women with low SES. These findings are consistent with hypotheses linking either the estriol ratio or the frequency of anovular cycles to breast cancer risk. PMID- 6928990 TI - Comparison of epoxide and free-radical mechanisms for activation of benzo[a]pyrene by Sprague-Dawley rat liver microsomes. AB - Coincubation of [6-3H]benzo[a]pyrene ([6-3H]BP) and [14C]BP with SD rat liver microsomes produced metabolic profiles that showed that the C-6 of BP was not affected by formation of 4,5-dihydro-4,5-dihydroxy-BP, 7,8-dihydro-7,8-dihydroxy BP, and 9,10-dihydro-9,10-dihydroxy-BP nor the 3- and 9-phenols of BP. Complete retention of tritium at C-6, except in the three quinones, confirmed the radical cation model for formation of the 6-oxo-radical followed by oxidation to quinones. Epoxide formation at the carcinogenically active regions of BP appeared to biochemically isolate from 6-position activation and suggested that the microsomal epoxide pathway is unrelated to the radicalcation scheme. These molar ratios derived from double-label experiments reinforced the current literature that indicates the epoxide mechanism as the major pathway toward carcinogenic forms of BP. PMID- 6928989 TI - Developmental pattern of 3-methylcholanthrene-inducible mutagenic activation of N 2-fluorenylacetamide, 2-fluorenamine, and 2,4-diaminoanisole in the rabbit. AB - The effects of 3-methylcholanthrene (MCA) on mutagenic activation of the carcinogenic arylamines N-2-fluorenylacetamide (FAA), 2-fluorenamine (FA), and 2,4-diaminoanisole (2,4-DAA) by liver homogenates were studied postnatally in Dutch rabbits. These effects were compared with the developmental profiles of cytochrome P448 and aryl hydrocarbon hydroxylase (AHH) activity. Mutagenic activation of FA and 2,4-DAA was increased by MCA as early as 2 days after birth, whereas induction of FAA mutagenicity appeared 6 days after birth. Thereafter, induction of all three arylamines closely paralleled induction of cytochrome P448, which was maintained into adulthood. In contrast, induction of AHH activity by MCA was highest at 2 days of age and decreased to control levels 20 days after birth. PMID- 6928992 TI - Multisequential transformation of a pig cell line (PFT): correlations between tumorigenicity and chromosome and ultrastructural markers. AB - Cells from representative subcultures of a continuous cell line of pig uterine tube (PFT) and carrying none, one, or two chromosome markers were inoculated in athymic nude mice (RCN) to determine the occurrence of the malignant transformation in this line. No tumors developed in mice after implantation of cells from either the 16th and 65th subcultures (no chromosome markers) or the 106th subculture (one chromosome marker, anchorage-dependent). Three adenomas (11.1%) were found in 27 mice that had been inoculated with anchorage-independent cells having one chromosome marker. Of 27 mice inoculated with cells showing two chromosome markers and gap junctions, 23 mice (85.1%) developed undifferentiated carcinomas. Ultrastructural traits and karyotypes of tumors were generally similar to those of the PFT cell inocula. However, annulate lamellae were found in 8 of 13 tumors examined by electron microscopy but were not seen in PFT cell inocula. The occurrence of a multisequential transformation was indicated by serial examination of the first 400 subcultures of the line and by comparison of the markers observed in three successive populations of cells differing in their genetic constitution. PMID- 6928991 TI - Initial DNA damage and heritable permanent change in pepsinogen isoenzyme pattern in the pyloric mucosae of rats after short-term administration of N-methyl-N' nitro-N-nitrosoguanidine. PMID- 6928993 TI - Inhibition of estrogen tumorigenesis in the Syrian golden hamster kidney by antiestrogens. PMID- 6928994 TI - Cytotoxicity of adriamycin combined with methotrexate against L1210 leukemia in mice. AB - The combination of adriamycin and methotrexate was found in mice to be synergistic in cytotoxicity to L1210 leukemia cells for a range of time intervals between the two agents. Cytotoxicity for normal hematopoietic stem cells was less than additive. Spleen colony assays were used to quantitate both cell populations. Increase in life-span assays yielded similar results. Also, the extent of synergy was dependent on the dose of adriamycin only. PMID- 6928995 TI - Induction of mammary neoplasms in the Sprague-Dawley rat by 430keV neutrons and X rays. AB - Female noninbred Sprague-Dawley rats were exposed to single doses of 0.28, 0.56, and 0.85 gray (Gy = 1 J/kg or 100 rads) of X-rays or 0.001, 0.004, 0.016, and 0.064 Gy of 430-keV neutrons at 62 +/- 1 days of age and were then observed over the rest of their lives for the appearance of mammary neoplasia. As mammary neoplasms were detected, they were removed and given a classification of adenocarcinoma(s) (AC) or fibroadenoma(s) (FA) after microscopic study. All irradiated groups exhibited an increased incidence of mammary neoplasia. The tumor rate increased steeply with age of the animals, and the effect of the irradiation could be adequately described as a forward shift in time of the spontaneous incidence. The cumulative prevalence was derived from first neoplasms only, and a formalism was presented that makes it possible to derive the integral tumor rate from all neoplasms in all animals. Mortality-corrected cumulative prevalences and integral tumor rates as a function of age were given for the different doses and separately for FA and AC. The mammary FA response and the total mammary neoplastic response (including both FA and AC) were approximately proportional to the absorbed dose of X-rays or the square root of the neutron dose. The relative biological effectiveness (RBE) of the neutrons increased with decreasing dose and reached values exceeding 100 at a neutron dose of 1 mGy; the single dose of 1 mGy of neutrons produced a significant increase of the tumor rate that corresponded to a foward shift or roughly 35 days of the spontaneous incidence. The AC, taken separately, were subject to considerable statistical uncertainties due to their small numbers. However, their RBE-dose dependence was consistent with that for the FA and, even at the highest dose studied, the RBE value exceeded 10. The nonrandom development of multiple FA within individual animals appeared to be the result of differences in susceptibility to radiation. However, mammary FA and AC within individual animals were not statistically correlated. PMID- 6928996 TI - Thymomas induced by simple alkylating agents in C57BL/Cbi mice: kinetics of the dose response. AB - Specific-pathogen-free inbred C57BL/Cbi mice (adult virgin females) were given single sublethal doses of N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea and were studied for a lifetime for the development of thymomas. A fatal lymphocytic lymphoma with a "starry sky" pattern due to the presence of macrophages was induced in the thymuses of treated mice within 250 days of treatment. Control and low-dose treatment groups had up to 70% incidence of a histiocytic lymphoma that was usually primary in mesenteric lymph nodes and nearly always occurred later than 250 days after treatment. A "one-hit" linear relationship existed between the time of appearance of induced thymic lymphomas and the log fraction of non tumor-bearing mice. The absolute latency period of these tumors was constant and independent of dose. The effect of dose was an exponential increase of the total incidence of induced thymic lymphomas. By mathematical analysis, the best estimate of the exponent from the results was 2 or 3, indicating that the development of these induced tumors may be produced by 2 or 3 "events" in the target cell. Possible candidates for these events are premutagenic alkylation of DNA, inactivation of DNA repair, oncovirus activation, regenerative hyperplasia, development of trisomy No 15, and inhibited immunosurveillance. PMID- 6928997 TI - Effects of 9,10-anthracenedione, 1,4-bis[[2-[(2-hydroxyethyl)amino]-ethyl]amino] , diacetate on cell morphology and nucleic acids of friend leukemia cells. AB - Treatment of Friend leukemia cells for 18 hours with 9,10-anthracenedione, 1,4 bis[[(2-hydroxyethyl)amino]ethyl]amino]-, diacetate (ANT) at concentrations up to 1.0 microgram/ml induced significant changes in cell metabolism and structure. Alterations in cell nucleic acid content were detected in cells stained with acridine orange under conditions such that DNA and RNA contents could be measured simultaneously by flow cytometry. Cells treated for 18 hours with ANT at concentrations of 0.05-0.1 microgram/ml became partially blocked at the G2 phase. In addition, about 30% of the cells became polyploid and demonstrated diplochromosomes at the 8C level of mitosis. The nuclear chromatin of blocked cells had an altered structure as reflected by a change in sensitivity of DNA in situ to denaturation induced by low pH. All viable cells treated with ANT for 18 hours at concentrations of 0.4-1.0 microgram/ml were blocked in G2 phase. These cells had significantly more RNA than did untreated cells. Transmission electron microscopic observations of thin-sectioned cells suggested that this increased RNA content in ANT-treated cells was mostly due to an approximately 50% increased cell diameter and partly due to a disproportionate increase in nucleolar size. In addition, electron microscopy revealed that ANT caused increased chromatin condensation and granulation. The drug had no apparent effect on production of the endogenous Friend murine leukemia virus. PMID- 6928998 TI - Virus and cell requirements for Friend virus granulocytic leukemogenesis in long term bone marrow cultures of NIH swiss [N:NIH(S)] mice. AB - The effect of hematopoietic stem cell age on leukemogenesis in vitro was tested in nonrecharged, corticosterold-supplemented NIH Swiss [N:NIH(S)] mouse long-term bone marrow cultures infected with Friend murine leukemia virus of anemia inducing strain (F-MuLV-A) or spleen focus-forming virus (SFFV) [Rauscher murine leukemia virus (R-MuLV)], a pseudotype virus derived by rescue of the SFFV genome from SFFV-Balb/3T3 clone A31 nonproducer cells with clonal helper R-MuLV. Cultures at 33 degrees C derived from 10-day-old or adult mouse marrow generated colony-forming unit culture granulocytic macrophage (CFUc) progenitor cells for over 20 weeks and colony-forming unit spleen cells for 14 weeks and generated permanent granulocytic leukemia cell lines after infection with F-MuLV-A at week 1, 2, or 4 but not at week 8. Leukemia lines were of granulocyte phenotype whether induced by F-MuLV-A or SFFV (R-MuLV) and synthesized myeloperoxidase and lysozyme but were restricted in ability to generate superoxide in response to phorbol myristate acetate stimulation. Cultures (31 degrees C) infected with temperature-sensitive (ts) helper virus mutant pseudotypes of SFFV as well as SFFV (R-MuLV) generated granulocytic leukemia lines, whereas only SFFV (R-MuLV) pseudotype virus-infected cultures became leukemic at 37 degrees C. R-MuLV wild type or ts mutant helper virus infection alone increased cell proliferation and numbers of CFUc but did not generate leukemia. These data indicated that gene(s) specific to F-MuLV-A or a virus rescued from SFFV-Balb/3T3 clone A31 nonproducer cells are required for transformation in vitro of a hematopoietic stem cell present in early but absent in late bone marrow cultures. PMID- 6928999 TI - Permanent cell lines from erythrophoromas in goldfish (Carassius auratus). AB - Attempts to establish permanent cell lines from spontaneous erythrophoromas (tumors derived from red pigment cells or erythrophores) of goldfish were made with the use of biopsy specimens from 12 tumors in 10 fish. Three cell lines were established that grew in vitro in synthetic medium (L-15 or Dulbecco's modified Eagle's minimum essential medium) supplemented with 20% fetal bovine serum for more than 8 months. One of these lines (GEM-81) with high proliferative activity was cultured for over 200 generations without an obvious change in growth rate. From this cell line, clonal cultures were obtained that formed clones with relatively intense yellow pigmentation. Descendants of these cell lines and clones contained low but detectable amounts of pteridine pigments (such as 7 hydroxybiopterin, biopterin, xanthopterin, and isoxanthopterin) and numerous cytoplasmic organelles analogous to pterinosomes. Both these characteristics are phenotypic markers of normal erythrophores and their neoplastic counterparts. After numerous subcultivations, these long-term cultures differed from those of the initial explants in having much lower contents of total pteridines and relatively lowered contents of 7-hydroxybiopterin. As manifestations of their neoplastic origins, all cell lines examined showed disoriented growth with dense focal mounding in monolayer cultures. The population doubling time of the uncloned GEM-81 cell line was 31 hours at 35 degrees C over a feeder cell layer and 3 days at 25 degrees C without feeder cells. Injection of cultured cells (1.5 x 10(7) cells/fish) into normal goldfish that had not been immunosuppressed did not give rise to tumors within 5 months. PMID- 6929000 TI - Effect of cytoskeleton-disrupting agents on the metastatic behavior of melanoma cells. AB - The effects of treatment with colchicine, cytochalasin B, and low temperature (4 degrees C) on the metastatic behavior of the B16-F10 melanoma cell line were examined. The growth of metastases and the distribution of radiolabeled tumor cells were monitored in inbred C57/BL6 mice given iv injections of B16-F10 cells. Cells treated previously with both drugs, but not with low temperature, produced fewer lung nodules than did control cells and displayed alterations in tumor dissemination patterns. In vitro studies revealed that both drugs reduced the rate of adhesion of the tumor cells to bovine endothelial cell monolayers, the rate of migration from agarose droplets, the formation of homotypic aggregates, and agglutination by wheat germ agglutinin. The drugs also induced morphologic alterations of the cells grown in monolayer culture but had little effect on cell volume. PMID- 6929001 TI - Rhodium (II) butyrate: a potential anticancer drug with cell cycle phase-specific effects in HeLa cells. PMID- 6929002 TI - Time-dependent changes in drug sensitivity expressed by mammalian cells after exposure to trypsin. AB - Immediately after a 5-minute exposure to 0.025% trypsin, Chinese hamster ovary cells treated with anticancer drugs exhibited changes in drug sensitivity. Depending on the drug, cells immediately became more sensitive, less sensitive, or showed no change in sensitivity at all. The deviation from normally expected survival values ranged from fourfold to fifty-fold and varied with time (of drug treatment) after trypsinization. By the 12th hour post trypsinization, the drug survival responses had returned to values obtained with untrypsinized cells. PMID- 6929003 TI - Modulation of thymus-leukemia antigens on mouse leukemia cells induced by IgG, but not IgM, antibody. AB - Exposure of mouse leukemia cells bearing thymus-leukemia (TL) surface antigens to whole TL alloantiserum has previously been shown to desensitize the cells to subsequent lysis by guinea pig complement (C) and fresh antiserum (antigenic modulation) and to correlate with the ability of cells to escape immune destruction in mice immunized against TL antigens. Tested in vitro, IgG of TL.1,2,3,5 antiserum modulated RADA1 leukemia cells (TL.1,2,3,5) completely within 2 hours at 37 degrees C when fully sensitizing amounts were used, with normal mouse serum as a source of C3. Similar results were obtained with IgG1, IgG2a, and IgG2b fractions of TL antiserum. An IgG2a monoclonal TL.3 antibody also completely modulated TL.3 antigens and partially modulated all antigens detected with TL.1,2,3,5 antiserum. IgM anti-TL.1,2,3,5 failed to modulate RADA1 cells even after 6 hours in vitro when fully sensitizing amounts of antibody were used. An IgM monoclonal TL antibody also failed to induce modulation. Modulation did occur on cells incubated with fully sensitizing amounts of IgG and IgM TL.1,2,3,5 antibody simultaneously, and nearly all cell-bound immunoglobulins were IgG. In mice passively immunized with IgG TL antibody, RADA1 cells modulated completely within 24 hours, whereas no modulation occurred during 4 days in mice immunized with IgM antibody. However, in both instances, tumor cells grew actively, which indicated that tumor escape did not depend on achievement of a modulated state. PMID- 6929005 TI - Chromosome fragility in New Zealand black mice: effect of ultraviolet and gamma radiations on fetal fibroblasts in vitro. AB - The sensitivity of fibroblasts cultured from New Zealand Black (NZB) and BALB/c mouse fetuses to UV and gamma radiations was tested with two methods: 1) colony forming ability and 2) chromosome abnormalities. When compared with BALB/c cells, NZB cells had reduced colony-forming ability and increased chromosome abnormalities after UV irradiation. However, no differences were seen in colony formation or frequency of chromosome abnormalities between NZB and BALB/c cells after exposure to gamma radiation. This apparent UV specificity strengthens the suggestion that NZB mice might be used as a model to study the relationship between chromosome abnormalities and cancer in human syndromes such as xeroderma pigmentosum, which is characterized by chromosome instability. PMID- 6929004 TI - Histology, histochemistry, and acid phosphatase of Noble (Nb) rat prostate adenocarcinomas and treatment of an androgen-dependent Nb rat prostate adenocarcinoma. PMID- 6929006 TI - Multistage models and primary prevention of cancer. AB - Removal of carcinogenic exposures should reduce the subsequent risk for developing cancer. Of interest are the extent of the reduction and the speed with which it takes place. Multistage models with more than two stages for tumor development predict different patterns of chaniging risk following removal of a carcinogenic exposure, depending upon the stage in the process that the carcinogen predominantly affects. The fall in risk following removal of a early stage carcinogen is only slowly evident, whereas removal of a late-stage carcinogen leads to a more rapid reduction in excess risk. Experimental and epidemiologic data are reviewed, and both early- and late-stage effects are seen. The long-term danger arising from entry into the environment of early-stage carcinogens is discussed, and it is shown that by the time human evidence that a hazard does exist becomes available, those already exposed may well have accumulated their fully effective doses. PMID- 6929007 TI - Specific blastogenic response of peripheral blood lymphocytes from lung cancer patients to a fetal lung antigen. AB - A human lung tumor fetal-associated antigen (LTFA) has been purified from lung tumor tissue by a combination of salt precipitation and ion-exchange chromatography. The purification steps were monitored by double immunodiffusion with the use of a rabbit anti-LTFA-specific antiserum. The isolated protein was tested for its blastogenic properties toward peripheral blood lymphocytes (PBL) by [3H]thymidine incorporation. PBL obtained from 25 healthy individuals, 34 patients with tumors other than lung tumors, 13 patients with lung diseases other than lung tumors, and 51 lung tumor-bearing patients were tested. Only PBL with an in vitro positive response to phytohemagglutinin were employed. Whereas PBL of lung tumor patients showed a significant blastogenic response to the purified antigen in 14 of 22 patients tested (60%), PBL of other patients were completely unreactive (P less than 0.005). The present data suggested that a specific immune response toward an LTFA was present in patients with lung cancers. PMID- 6929008 TI - Epithelial blood group antigens in human carcinomas of the distal colon: further studies on their pathologic significance. AB - Blood group antigen content of human carcinomas located in the distal large bowel (descending colon, sigmoid colon, and rectum) was determined by the specific red cell adherence reaction and was compared to several morphologic features of prognostic significance, e.g., differentiation, extent of tumor spread, peritumoral lymphoplasmocytic infiltration, and growth patterns. About 50% of the carcinomas expressed blood group antigens in either diffuse or patchy distribution. Classification of tumors according to the extent of local spread revealed that 60% of Dukes stage A tumors were blood group antigen-negative, whereas 58% of those in Dukes stage B were positive. Dukes stage C lesions had an intermediate position, and this limits the prognostic usefulness of blood group antigen determinations. No significant correlations were found between blood group antigenicity and the degree of histologic differentiation, the degree of peritumoral lymphoplasmocytic infiltration, and the mode of tumor growth. PMID- 6929009 TI - Tumorigenicity of human malignant melanocytes in nude mice in relation to their differentiation in vitro. AB - Of 16 cell lines derived from 12 human melanomas obtained from 11 patients, all were established as permanent cell lines: 7 from primary tumors and 9 from metastatic tumors. Study of the early subcultures and established cell lines showed that melanocytes passed through a phase of dedifferentiation during which they took on a fibroblast-like appearance and were hypodiploid and nontumorigenic in nude (thymus-deficient) mice. Phenotypic modulation in vitro was shown to be dependent on the culture medium. The lines varied considerably in karyologic and phenotypic expression (as assessed by morphologic appearance and 5-S cysteinyldopa production). Fibroblast-like, epithelioid, nonpigmented, achromic, and pigmented cells were obtained from the same tumor. Heterotransplantation into nude mice revealed wide variations in tumorigenicity: The latency of the tumors, their size, and infrequent metastases bore no relationship to the phenotypic modulation of the melanocytes as expressed in vitro. Melanogenesis is therefore not related to malignancy; they are two independent characteristics. PMID- 6929010 TI - Breast cancer and reproductive history from genealogical data. AB - With the use of data from the Utah State Cancer Registry and Utah genealogical data, an analysis of 236 breast cancer patients and 937 controls matched on year of birth showed that a late age at the birth of the first child was most strongly associated with incidence of breast cancer (relative odds = 2.0; P less than 0.001). A strong interaction was found between age at first delivery (AFD) and age at last delivery (ALD). The association of AFD with breast cancer incidence was strongest for women with an ALD before 35 years of age even after adjustment for partly (relative odds = 4.1; P less than 0.001). Decreased parity was not significantly associated with breast cancer. PMID- 6929011 TI - Incidence of malignant thyroid tumors in humans after exposure to diagnostic doses of iodine-131. I. Retrospective cohort study. AB - Between 1952 and 1965, 10,133 patients received an average of 60 mu Cl of 131I for diagnostic examinations of the thyroid gland. The examinations were mainly done on adults, and only 5% of the patients were younger than 20 years at the time of examination. Of the patients, 9 appeared in the Swedish Cancer Registry between 1958 and 1977 with a diagnosis of malignant tumor of the thyroid gland more than 5 years after the administration of 131I. Inasmuch as the expected number of malignant thyroid tumors computed from Swedish cancer incidence figures was 8.3, there was no elevation of the incidence of malignant thyroid tumors in these patients receiving diagnostic doses of 131I. The patients were examined because of a suspected thyroid dysfunction and therefore represented a selected group. The investigation is being continued to analyze further parameters that could have a bearing on these results. PMID- 6929012 TI - Demonstration of an altered S-adenosylmethionine synthetase in human malignant tumors xenografted into athymic nude mice. AB - S-Adenosylmethionine synthetase isoenzymes (EC 2.5.1.6) were studied in human malignant tumors xenografted into athymic nude mice and were studied in normal human and rat tissues. The tumors included 7 melanomas; 4 colon carcinomas; 3 each of mammary, cervical, and ovary carcinomas; 2 each of lung carcinomas and sarcomas; and 1 each of lymphoma and stomach and nasopharyngeal carcinomas. The presence of an altered intermediate Michaelis constant (Km) isoenzyme, previously shown to be a unique characteristic of rat neoplastic tissues, in these tumors was invariably detectable, though the presence of the low-Km isoenzyme characteristic of the enzyme of normal tissues was also evident in many of these tumors. Only tumors demonstrating high rates of growth were devoid of the low-Km isoenzyme. The low-Km isoenzyme was the only enzyme detectable in many normal human and rat tissues. Thus this isoenzyme was probably the common enzyme of all tissues. Some additional organ-specific isoenzymes were found, e.g., in the liver and lactating mammary gland. The low-Km isoenzyme in malignant tumors was altered to assume a considerably higher Km value, and this alteration appeared to be a common aberration of malignant tumors. PMID- 6929014 TI - Metastasis-enhancing effect of heparin and its relationship to a lipoprotein factor. AB - The effect of low-dose heparin on spontaneous metastasis formation was studied with the PA-III rat prostate adenocarcinoma cell line model system. In LW rats given heparin iv at a dose of 1,000 U/kg body weight (three times/wk), the metastatic spread of implanted PA-III cells from the footpad through ipsilateral lymphatics to the lungs was enhanced. The weights of the draining lymph nodes (popliteal, inguinal, and axillary) and the number of lung tumor colonies were significantly increased compared with those in the saline-treated control tumor bearing rats. The growth of the primary tumor was also enhanced. Heparin alone did not induce enlarged lymph nodes in rats nor did it change the growth pattern of PA-III cells in vitro. The accelerated metastatic spread of the PA-III cells was possibly related to the destruction of the oncolytic activity of the very low density lipoprotein by the lipoprotein lipases induced by the iv administration of heparin. However, the possibility that other mechanisms could be operative in this phenomenon has not been ruled out. PMID- 6929017 TI - Protection of mice against syngeneic C1300 neuroblastoma challenge by immunization with membranes of C1300 neuroblastoma cells. AB - Male A/J mice 2-3 months old were inoculated sc with membranes from syngeneic C1300 neuroblastoma cells (clone NB6R) in complete Freund's adjuvant. Significant immunoprophylaxis was noted in the sensitized mice upon sc challenge with viable NB6R cells. During the experiment (60 days from viable cell challenge), each control mouse developed a palpable tumor and died within 50 days. Complete protection was obtained with a program of 4 inoculations of NB6R cell membranes. Each mouse given only 1 inoculation of NB6R cell membranes developed a palpable tumor, but afer 60 days only 1 mouse in 7 had died, which indicated a significant degree of protection. With in vitro tests of lymphocyte proliferation, rosette formation, and complement fixation, it was shown that these mice had mounted both cellular and humoral immune response against the tumor cells. PMID- 6929016 TI - Morphology and histogenesis of anal region and clitoral gland tumors induced in mice by 1,2-dimethylhydrazine. AB - Ninety-seven tumors induced in the anal region in female CBA and BALB/c mice by 1,2-dimethylhydrazine were examined histologically. Tumors originated mainly from the following sources: epidermis (papillomas and basal cell neoplasms), pilosebaceous complexes of the anal region (keratoacanthomas, cystic squamous cell tumors, and adenomas of the perianal sebaceous glands), and clitoral (preputial) glands (adenomas and adenoacanthomas). A subcutaneous location and late ulceration were characteristics of many tumors originating from the pilosebaceous complexes and clitoral glads. From 31 to 43% of all anal tumors were of sebaceous gland (perianal or clitoral) origin. Cystic squamous cell tumors were morphologically similar to type II keratoacanthomas of rodents. Squamous cell tumors of any origin finally became squamous carcinomas. PMID- 6929015 TI - Histogenesis and dose dependence of N-methyl-N-nitrosourea-induced carcinoma in a localized area of the hamster trachea. AB - The effect of the number of weekly intratracheal Instillations of N-methyl-N nitrosourea (MNU) on induction of tracheal tumors was studied in male noninbred Syrian golden hamsters. The histogenesis of metaplastic and neoplastic lesions was also characterized. Treatment of hamsters once weekly for either 6, 8, 10, 12, or 14 weeks with a 0.5% solution of MNU resulted in the induction of a 0, 6, 11, 26, and 42% incidence of carcinoma, respectively, at 6 months after the first MNU treatment. Of the carcinomas induced, 87% were combined epidermoid and adenocarcinomas, whereas 13% were epidermoid carcinomas. In animals killed 1 week following either 1, 3, 6, 8, 10, 12, or 14 treatments, a continuum of metaplastic and neoplastic changes was observed that correlated well with the cancer incidence exhibited at the termination of the study. Mucous cells were found to be of prime importance in the development of the metaplastic and neoplastic tracheal lesions observed. PMID- 6929018 TI - Nuclear magnetic resonance relaxation and water contents in normal mouse and rat tissues and in cancer cells. AB - By studying nuclear magnetic resonance water proton spin-lattice relaxation times (T1 and T2) of normal mouse and rat tissues at varying water contents and by comparing the data with those obtained from five types of cancer cells in ascites form, we concluded that differences in total water contents between normal tissues and cancer cells contribute less than 10% to the differences between the longer T1 of cancer cells as compared to the T1 of normal tissues. In spite of the diverse origin of the five types of cancer cells studied, their T1 and T2 as well as water contents were confined within relatively narrow limits. We suggested that all 5 ascites tumors studied are maximally deviated and that the physical state of the water in all maximally deviated cancer cells is very similar. PMID- 6929013 TI - Trends in cancer incidence and mortality in the United States, 1969-76. AB - Trends in cancer incidence and mortality in the United States were analyzed over the period 1969 through 1976. The greatest increase in incidence among whites occurred for lung cancer among females (almost 9%/yr), whereas the incidence of cancer of the uterine corpus increased 6% per year. Cancer of the cervix showed the greatest decrease in incidence, an average of 6% per year. Stomach cancer incidence and mortality showed a substantial decline for each sex, and rectal cancer incidence increased for each sex whereas mortality declined. The incidence of cancer of the female breast increased 1.8% per year without inclusion of the rates for 1974 and 1975, when an unusually large increase occurred. Cancer mortality data were presented for the total United States on the basis of data from the National Center for Health Statistics. Emphasis was focused on the comparability of cancer incidence data over the time period studied, given the fact that cancer incidence was measured by the Third National Cancer Survey for the period 1969-71 and by the Surveillance, Epidemiology, and End Results Program for the period 1973-76. Each survey covered approximately 10% of the U.S. population but had four geographic areas in common. Investigation of the comparability of these two surveys revealed that the incidence rates for whites were sufficiently comparable to permit an analysis of trends in cancer incidence over the entire period 1969-1976. Such comparability was not found for blacks. Therefore, cancer incidence data are presented only for whites, but cancer mortality data are presented for both whites and blacks. PMID- 6929019 TI - Spontaneous endomyometrial neoplasms in aging Chinese hamsters. AB - Twenty-one endomyometrial neoplasms among 93 nulliparous noninbred Chinese hamsters were evaluated. The median survival time of the 93 females was 1,040 days. The median age of hamsters with endomyometrial neoplasms was 1,200 days. Neoplasms were classified as carcinoma or malignant mixed mullerian tumors of the endometrium and benign or malignant myometrial neoplasms. There were 13 endometrial adenocarcinomas. Three tumors were mixed adenosquamous carcinomas, which occurred in significantly older Chinese hamsters than did adenocarcinomas. Three malignant mixed mullerian tumors consisted of 2 carcinosarcomas and 1 mixed mesodermal tumor. The 2 myometrial neoplasms were a leiomyoma and a leiomyosarcoma. The classification and relative frequency of these neoplasms were similar to endomyometrial neoplasms of women, which makes Chinese hamsters useful subjects for studies of spontaneous endomyometrial cancers. PMID- 6929020 TI - Carcinogenicity of tumor cell populations: origin of a putative H-2 isoantigenic loss variant tumor. AB - The properties of an unusual mouse tumor capable of extremely rapid and widespread spontaneous metastatic growth were recently described; this tumor, called MDAY-D2, at first appeared to be an H-2Kk loss variant of an (A X DBA/2)F1 (H-2KkDd) sarcoma called MDAY and was obtained by serial ip passage of MDAY in DBA/2 (KdDd) mice. The studies described here were concerned with the analysis of the origin of MDAY-D2; i.e., was it a true variant or a newly induced DBA/2 tumor? Several approaches were used, most of which exploited defined cell surface alloantigenic systems as natural genetic markers. The results indicated that MDAY D2 was indeed a newly induced DBA/2 tumor and, furthermore, that MDAY was a homozygous A-strain tumor, probably a T-cell lymphoma. Thus a) MDAY was found to be Ly-1.2+, Ly-2.2+, and Thy-1.2+, but Ly-6.2-, whereas the opposite pattern was observed with MDAY-D2; b) MDAY possessed the private and public H-2 specificities associated with H-2k and H-2Dd, but not H-2Dk [i.e., it typed as an A-strain (H 2a) tumor, not as (A X DBA/2)F1]; c) MDAY-D2 possessed private and public specificities associated with H-2Kd and H-2Dd and was found to be H-2Kk-negative [i.e., it typed as a DBA/2 (H-2d) tumor]; d) serial injection of clonally derived ouabain-resistant H-2Kk-positive MDAY cells into DBA/2 hosts led to the rapid development of an MDAY-D2 (H-2d-positive) tumor that was fully ouabain-sensitive. Several findings did not support a contaminant theory to explain induction of MDAY-D2. The rapid induction of a tumor after injection of allogeneic tumor cells may have importance in relation to oncogenesis, tumor variant formation, and tumor progression. The results showed that tumor cells themselves can be potent carcinogens. PMID- 6929021 TI - In vitro transformation of fetal brain cells from CDF rats exposed in utero to N ethyl-N-nitrosourea: morphologic and immunologic studies. AB - Inbred CDF rats received 250 mg N-ethyl-N-nitrosourea (ENU)/kg body weight in monosodium phosphate buffer (pH 5.5) during late pregnancy (18-21 days). Control rats received only buffer. One hour after ENU or buffer administration, the fetuses were delivered and fetal brain cells (FBC) were put in long-term tissue culture. Cell growth consisted of monolayers of glial, fibroblastic, and epithelial-like cells. FBC from buffer-treated rats could not be subcultured for more than 13-15 passages; only one culture was maintained up to the 26th passage. FBC from ENU-treated rats showed in vitro malignant transformation beginning at the 8th passage (100 days). Injection of these cells sc into irradiated or neonatally thymectomized syngeneic rats induced small palpable tumors that regressed completely by 15-28 days. Small nonprogressively growing subcutaneous tumors in normal rats, however, were obtained only after the 19th in vitro passage (200 days). These transformed FBC appeared highly antigenic. Tumor associated antibody was demonmmune adherence assays. Rats immunized with irradiated malignant FBC showed rising tumor antibody titers. The antibody was absorbed by ENU-exposed FBC but not by normal fetal or adult syngeneic brain cells. We concluded that ENU-exposed cells become malignant when grown in vitro for at least 8 passages (100 days) but grow in vivo in X-irradiated or neonatally thymectomized rats only. These antigenic and tumorigenic clones may be selected in vitro, where they grow readily in the absence of immune resistance. PMID- 6929022 TI - Selection and in vivo properties of lectin-attachment variants of malignant murine lymphosarcoma cell lines. PMID- 6929025 TI - [Differential diagnosis in fevers of unknown origin]. PMID- 6929024 TI - Is somatic mutation the major mechanism of malignant transformation? PMID- 6929023 TI - Comparison of the level of cellular retinoid-binding proteins and susceptibility to retinoid-induced growth inhibition of various neoplastic cell lines. AB - The presence and level of cellular retinol-binding protein (CRBP) and cellular retinoic acid-binding protein (CRABP) were determined in several neoplastic cell lines. These cells exhibited different degrees of susceptibility to growth inhibition in culture by two retinoids, retinyl acetate and retinoic acid. CRABP was detected in 10 and CRBP in 3 of the 11 tested cell lines. The levels of CRBP and CRABP were in the ranges 15-3,400 and 4-1,290 pmol per 10(9) cells, respectively, as determined by sucrose gradient centrifugation. Cell lines that contained CRABP included S91 and B16 melanomas; Mm5mT and DMBA No. 8 mammary adenocarcinomas; BW5147, BW5147.RicR, and P3 neoplastic lymphoid cells; F361.2 (a hybrid cell line obtained by fusion of MSV3T3 and BW5147); MSV3T3 sarcoma; and RAW8 lymphosarcoma. All but the last two cell lines were inhibited by retinoic acid in culture. CRBP was detected in extracts of S91, Mm5mT, and RAW8. Retinyl acetate inhibited the growth of all cell lines with the exception of RAW8, MSV3T3, and F361.2. No correlation was found between the level of either binding protein and the extent of growth inhibition by either retinyl acetate or retinoic acid. Neither of the binding proteins was detected in L1210-A5 leukemia cells, whose proliferation can be inhibited by both retinyl acetate and retinoic acid. These data indicated that screening cell lines for the presence and level of CRBP and CRABP is not sufficient to predict the susceptibility of cultured cells to growth inhibition by retinoids. PMID- 6929026 TI - Cancer in children at the medical university hospital: update 1980. PMID- 6929027 TI - Intraocular lens implants. PMID- 6929028 TI - Subclavian artery obstruction. PMID- 6929030 TI - Genetic recombination: formal implications of a crossed strand-exchange between two homologous DNA molecules. PMID- 6929029 TI - AMA interim meeting in Honolulu, December 2-5, 1979. PMID- 6929035 TI - Cholinergic treatment in the Tourette syndrome. PMID- 6929036 TI - Patenting nature's secrets and protecting microbiologists' interests. PMID- 6929034 TI - Cholinergic treatment in the Tourette syndrome. PMID- 6929032 TI - Myeloblastic leukemia and leukemic meningitis in a dog. PMID- 6929031 TI - Construction of a partial diploid for the degradative pathway encoded by the TOL plasmid (pWWO) from Pseudomonas putida mt-2: evidence for the positive nature of the regulation by the xyIR gene. PMID- 6929033 TI - Low-dose radiation and leukemia. AB - We investigated the effect of diagnostic and low-level therapeutic radiation (less than 300 rads to the bone marrow) on the development of leukemia. During this study, 138 patients with leukemia (representing all known incidence cases of leukemia in residents of Olmsted County, Minnesota, between 1955 and 1974) were each matched with two controls, and the lifelong experiences of both groups with regard to diagnostic and therapeutic radiation were ascertained. No statistically significant increase was found in the risk of developing leukemia after radiation doses of 0 to 300 rads (3 Gy) to the bone marrow when these amounts were administered in small doses over long periods of time, as in routine medical care. PMID- 6929038 TI - [Exposure to radiation in percutaneous cervical cordotomy (author's transl)]. AB - During eleven high cervical percutaneous cordotomies using the image intensifier, the amount of exposure to X-radiation was measured at various sites on both the patient and the operator. The values lay below the maximum doses allowed by the radiation protection regulations (Rov; section 33. Para 1). PMID- 6929037 TI - Parallel bioassay of physalaemin and kassinin, a tachykinin dodecapeptide from the skin of the African frog Kassina senegalensis. AB - 1. Kassinin, a tachykinin dodecapeptide isolated from the skin of the African frog Kassina senegalensis was submitted to parallel bioassay with physalaemin, eledoisin and substance P, three major representatives of the tachykinin peptide family. Bioassay was carried out on blood pressure, salivary secretion and isolated or in situ smooth muscle preparations. 2. As expected, kassinin possessed the entire spectrum of biological activity peculiar to the tachykinins. However, among the examined tachykinins kassinin was the poorest stimulant of salivary secretion and the weakest hypotensive agent, while displaying very powerful stimulant effects on different smooth muscle preparations, especially on isolated preparations of urinary bladder. 3. Kassinin differed from the other tachykinins also for its more gradual and sustained action on several in situ and isolated preparations. The peptide most similar to kassinin in its spectrum of activity was eledoisin. 4. Emphasis is laid on the possibility to dissociate the effects of the tachykinins on different target systems through changes in the N moiety of the tachykinin molecule. PMID- 6929039 TI - Infradiaphragmatic spinal tumours demonstrated by transfemoral epidural venography. AB - During the last few years transfemoral epidural venography has increasingly been used for diagnosing lumbar disc herniation. Occasionally this method may reveal an unexpected malignant tumour with the clinical symptoms of lumbar disc disease. Therefore it is of interest to be acquainted with the venographic signs of malignancy in this area. Moreover transfemoral epidural venography can be of help in the delineation of a tumour in the vertebral canal. If the double-catheter method is used, the anterior epidural venous plexus will, as a rule, be adequately shown up to the level of T10. Occasionally higher thoracic levels also are visualised. The procedure can easily be performed on an out-patient basis and is well tolerated by the patient. The complication rate is very low. The use of ioxaglate (Hexabrix) minimizes the post-injection reactions to the contrast medium. PMID- 6929041 TI - Defining your obligations. PMID- 6929042 TI - A forerunner. PMID- 6929040 TI - Perspectives: resolving an ethical dilemma. PMID- 6929043 TI - Application of modified Millard's method for repair of unilateral cleft lips. PMID- 6929045 TI - The symposium. Part III. Dentistry yesterday, today and tomorrow. PMID- 6929044 TI - Dentistry faces the twenty-first century. PMID- 6929047 TI - Dentistry's primary concern. PMID- 6929046 TI - Trends in dental education. PMID- 6929048 TI - [Bronchoscopy in relaxation anesthesia under Sanders injector respiration]. PMID- 6929049 TI - [Translocation 21:12 in myelocytic leukemia]. PMID- 6929050 TI - Angiography of abdominal lymphomas. PMID- 6929051 TI - [Results and complications of cervix carcinoma treated by whole pelvis external irradiation alone (author's transl)]. PMID- 6929053 TI - [Measurement of CT-image resolution using a thin wire (author's transl)]. PMID- 6929052 TI - [An evaluation of 15-year results of postoperative telecobalt irradiation for breast cancer in relation to size, location of the original tumor and histological status of the regional lymphatics (author's transl)]. PMID- 6929054 TI - [Effect of X-ray irradiation on rat kidney (author's transl)]. PMID- 6929055 TI - [Comparative studies on the normal skin reactions to various radiations]. PMID- 6929056 TI - [Dental status in workers at a Norwegian factory. IV. Periodontal status]. PMID- 6929057 TI - [Financing of dental health care. I. The odontologic "Norwegian map" or status quo]. PMID- 6929058 TI - [A case of an impacted mandibular 1st molar. Case report]. PMID- 6929059 TI - [Financing of dental health care. II. Ways of financing]. PMID- 6929060 TI - [In vitro culture of granulopoietic precursors in dysmyelopoiesis. Prognostic value (author's transl)]. AB - 96 patients with a dysmyelopoiesis have had an in vitro study of bone marrow CFUc at the time of diagnosis. A correlation between in vitro growth characteristics and the transformation in acute leukemia (AT) was searched. We found 5 types of in vitro growth: 3 with a "non-leukemic" pattern IA, IB, and IC, and 2 with a "leukemic" pattern II and III. In the type IA (normal growth) there is few death (16%), all without AT. In the types IB and ic with decreased in vitro growth, 40% of patients dead without an at and 25% after an AT. In the types II (with excess of clusters) and III (clusters without colonies) an AT was almost the case. The specificity, the positive and negative predictive values of in vitro growth type for the study of an AT outcome were the best of all that we obtained in the study of biological parameters in the dysmyelopoiesis. The study of bone marrow CFUc in dysmyelopoiesis can separate a group of patients with high risk of an AT outcome, which could be ameliorate with chimiotherapy. PMID- 6929061 TI - [Acute granulocytic leukaemia: prognostic value of medullary caryotype (author's transl)]. AB - Thirty-nine cases of granulocytic acute leukaemia (AL) forming an homogeneous series were the object of a satisfactory chromosomal examination of the marrow by direct examination at the time of diagnosis. This group of patients was compared with another group of similar number where the conditions of patient referral, diagnosis and treatment were the same, in order to show that no selection was involved in the series studied. Medullary caryotype was found to be normal in 61,5% of cases. In such patients, the hope of complete remission and mean survival were significantly better than in cases where the caryotype was abnormal, and all the more so when the caryotype contained abnormalities in all the mitoses examined. For myeloblastic AL, the correlation between caryotype and the effects of treatment is very close (p less than 0,01). For the therapist, these results justify a new approach in the treatment of myeloblastic AL. PMID- 6929062 TI - Chloroma: rare manifestation of acute leukemia. PMID- 6929063 TI - [2 cases of chronic myeloleukemia with tumorous transformation]. PMID- 6929064 TI - [Use of hemodialysis in chronic myeloleukemia with acute renal insufficiency]. PMID- 6929065 TI - [Intravascular coagulation syndrome in acute leukemia]. PMID- 6929066 TI - [Importance of fibrin-fibrinogen degradation products in the pathogenesis of a coagulopathy in leukemias]. PMID- 6929067 TI - [Distribution of haptoglobin phenotypes in the families of hemophilia patients]. PMID- 6929068 TI - Ophthalmology in Rhode Island--1980. PMID- 6929069 TI - A new approach to continuing medical education. PMID- 6929070 TI - Radiographic case of the month: Gastric lymphosarcoma. PMID- 6929072 TI - Clinical Pathological Conference. Small, post-dates infant with severe respiratory distress. PMID- 6929071 TI - Aspirin intolerance presenting as chronic rhinitis. PMID- 6929073 TI - Soliditary rhabdomyosarcoma of the pericardium: a case report and pathologic discussion. PMID- 6929074 TI - On communications between professionals. PMID- 6929075 TI - Internships obtained by the Brown University medical students class of 1980. PMID- 6929076 TI - Radiographic case of the month. PMID- 6929077 TI - Categorization of hospitals in Rhode Island. PMID- 6929078 TI - Lennert's lymphoma--report of a case with unusual presentation and therapeutic implications. PMID- 6929079 TI - Prednisone therapy of gold-induced thrombocytopenia in a rheumatoid arthritis patient. PMID- 6929080 TI - Authority, freedom, and the teenager. PMID- 6929081 TI - Long-term effects of colchicine on dentinogenesis in rat incisors. AB - Colchicine in doses of 0.5, 1.0 and 1.5 mg/kg was administered to 15 rats divided in three experimental groups. Histomorphologic investigation of the maxillary incisors after 2 weeks revealed; 1) alterations in the odontoblasts mainly related to size, shape, polarity and staining properties, and 2) presence of irregular dentin separated from normal dentin by one or two incremental lines. The dentinal irregularities were dose-dependent and consisted of twisting of the dentinal tubules, globular formations and cellular inclusions in addition to niche-like defects. PMID- 6929082 TI - Caries increment and gingival status during 2 years' use of chlorhexidine- and fluoride-containing dentifrices. AB - A total of 91 schoolchildren, 13 years of age, were distributed into three groups. Three test dentifrices were used containing 0.1% NaF, 0.1% NaF and 2% chlorhexidine, and 2% chlorhexidine, respectively. The caries increment and gingival conditions over a period of 2 years were recorded. The caries data of the groups were compared and related to two reference groups in order to estimate a possible influence upon the study results by a change in caries incidence general to the area and age groups in question. There was less caries in the group using the dentifrice containing fluoride and chlorhexidine than in the two other test groups. The differences in caries increment between the groups were not statistically significant. The gingival health seemed to improve in all groups, but there were no statistically significant differences between the groups. The caries data from the reference groups indicated that the general trend towards reduced caries incidence was different from that of the study group. PMID- 6929083 TI - Effects of chlorhexidine and iodine on in vitro plaques of Streptococcus mutans and Streptococcus sanguis. AB - Both chlorhexidine and iodine showed greater antimicrobial effect on in vitro grown S. mutans plaque than on plaque composed of S. sanguis. One treatment with iodine for 8 min inhibited the acid production of S. Mutans plaque whereas S. sanguis plaque required 20 min to be similarly affected. In contrast one treatment with chlorhexidine for up to 20 min did not completely inhibit the acid production of plaque of either microorganism. Repeated short term exposures increased the bactericidal effect of chlorhexidine but not that of iodine. The difference in antimicrobial effect between chlorhexidine and that of iodine on S. mutans and S. sanguis should be investigated in persons heavily infected by S. mutans. PMID- 6929084 TI - In vivo effect of four antibacterial agents upon the acidogenicity of dental plaque. AB - The present study was carried out to compare the effect of chlorhexidine, iodine, alcohol and hydrogen peroxide on the acidogenicity of dental plaque in vivo. Plaque pH changes after application of sucrose were measured before and at various time intervals after the topical application of the agents. The MIC values of the different agents were assessed against plaque bacteria in vitro. The antimicrobial activity of chlorhexidine and iodine were similar whereas alcohol and hydrogen peroxide were less effective in the concentrations employed. The results showed that chlorhexidine 2%, iodine 2%, and alcohol 70% inhibited pH drops for a 24-h period after treatment whereas 3% hydrogen peroxide had no effect. Chlorhexidine 0.2% inhibited acid production to a greater extent than did alcohol 50% and iodine 0.2%. It is suggested that retention of chlorhexidine in plaque may explain the observed prolonged effect. PMID- 6929085 TI - Biological evaluation of root canal antiseptics using in vitro and in vivo methods. AB - Five antiseptics commonly used in endodontic treatment were evaluated with regard to cytotoxicity and initial tissue irritating effect. The cytotoxicity was evaluated in a cell culture system using HeLa cells and the initial tissue irritating effect was assessed by application of the antiseptics onto an intact nonepithelialized tissue surface. The cell response was assessed by registering changes in the DNA synthesis of the cells and the tissue response was assessed by registering changes in the oxidoreductase enzyme activity of the tissue. To evaluate the ability of the cells and the tissue to overcome an induced damage, one part of the study included a recovery period before the condition of the cells and the tissue was assessed. The most severe cell and tissue reactions were caused by 5% Chloramine-T whereas no differences in toxicity or tissue irritating effect were found between 0.04% Jodopax, 0.1% Biosept, 0.1% Hibitane, or 0.5% sodium hypochlorite. The HeLa cells showed the best recovery after having been influenced by Jodopax, Chloramine-T or sodium hypochlorite solutions, whereas the best tissue recovery was observed in the experiments with Biosept and Hibitane. PMID- 6929086 TI - Effect of oral hygiene education on children with and without subsequent orthodontic treatment. AB - The aim of the present investigation was to study whether an intense period of individual oral hygiene education would result in proper dental health behavior and to compare the effects of such education on 30 individuals undergoing subsequent orthodontic treatment and 30 controls without such treatment. The investigation consisted of two experimental periods: one period of oral hygiene education during which information on proper plaque control was given fortnightly for 6 weeks and one follow-up period of 30 months corresponding to the orthodontic treatment phase. The results suggest that it is possible to achieve and maintain a high standard of dental health behavior following an intense period of individual oral hygiene education. A certain deterioration of the gingival status was observed after 3 months in the orthodontically treated children. This was interpreted as being due to the influence of subgingivally located orthodontic bands. After 30 months a high level of oral hygiene and gingival status as well as a low caries activity were still apparent with only minor and insignificant differences between the children subject to orthodontic treatment and the controls. PMID- 6929087 TI - Pain, tenderness and strength of human mandibular elevators. AB - In terms of the mean voltage during maximal bite in the intercuspal position we compared the strength of the temporal and masseter muscles of 39 patients with functional disorders of the chewing apparatus and 45 controls. Maximal electrical activity was significantly stronger in the controls than in the patients. Differences between the two samples with respect to sex, age, number of opposing teeth in contact and the presence of pain and tenderness tended to favor stronger activity in the controls. However, the different levels of electrical activity, especially in the case of the masseter muscles, could only be accounted for on the basis of a difference in maximal strength. We suggest that the weaker elevator muscles of the patients was a predisposing factor making these muscles less fit to endure hyperactivity induced psychologically or as a reflex response to occlusal interferences and functional disorders of the temporomandibular joints or other elements of the oral neuromuscular system. The sample of controls had much stronger elevators, less susceptible to such hyperactivity. PMID- 6929088 TI - Distortion of maximal elevator activity by unilateral premature tooth contact. AB - In four subjects the electrical activity in the anterior and posterior temporal and masseter muscles during maximal bite was recorded bilaterally with and without premature unilateral contact. Muscle activity was measured as the average level and the peak of the mean voltage with layers of strips of 0.05, 0.10, 0.15 and 2.0 mm, placed between first molars either on the left or the right side, and compared with the level of activity with undistrubed occlusion. Unilateral premature contact caused a significant asymmetry of action in all muscles under study with stronger activity ipsilaterally. With increasing thickness of the overlay the mean voltage decreased in parallel on both sides. We suggest that the asymmetry was caused by larger spindle afferent activity on the ipsilateral as compared to the contralateral side, and that the all-over decrease of muscle activity was due to a gradual reduction of activity from periodontal pressoreceptors. PMID- 6929089 TI - Streptococcus mutans in plaque after mouth-rinsing with buffers of varying pH value. AB - After a period of mouthrinsing with a phosphoric buffer solution with low pH the proportional distribution of Streptococcus mutans in plaque from occlusal retention sites was significantly higher than after a control period. This indicates that colonization with S. mutans may be favored or that other microorganisms competing with S. mutans are inhibited under these circumstances. PMID- 6929090 TI - Symposium on pathophysiology and drug therapy of peptic ulcer. Lysebu, Oslo, 15 17 March, 1979. PMID- 6929091 TI - Motility and ulcer. PMID- 6929092 TI - The effect of antacid on gastric and duodenal bulb acidity. AB - A small glass pH electrode was positioned in the duodenal bulb and connected to a digital pH meter. The pH registered every half second was stored on a minidiskette with a capacity of 32.400 pH data on a single mini-disc. A microcomputer controlled electrode calibration, data collection, formating and storage. Four patients with duodenal ulcer were given a liquid test meal, and one hour later when gastric and duodenal acidity had reached high levels they were given 10 ml of antacid. From the stored pH data the mean pH and the mean hydrogen ion concentration was calculated. During the 10 min. period before antacid was given gastric pH was on average 1.5 and the duodenal pH on average 4 with a CH+ of 2.500 mumol/. Ingestion of antacid reduced gastric acidity to around pH 3, and the duodenal pH to 6 with a CH+ of 250 mumol/l. This effect of antacid was observed in all subjects, but the degree and the duration of the effect varied very much between the individuals. PMID- 6929093 TI - The effect of trimipramine, cimetidine and atropine on gastric secretion. AB - A comparison was made of increasing doses of trimipramine (0.05-0.40 mg/kg/h), atropine (7-28 microgram/kg/h) and cimetidine (0.30-2.40 mg/kg/h) on the gastric secretion stimulated by 3 microgram/kg/h of histamine dihydrochloride as continuous infusion, each dose step lasting 30 minutes. In 9 healthy subjects it was found that trimipramine had no significant effect on the output of acid. The largest dose of atropine caused a reduction by 77%, and cimetidine a reduction of 89% during the last 15 minutes portions. The study suggests that the healing of peptic ulcer by trimipramine is not linked to the effect on the histamine stimulated gastric acid secretion. PMID- 6929094 TI - The possible significance of the central action of trimipramine in the treatment of functional "non-ulcer" dyspepsia, and peptic ulcer with masked depression. PMID- 6929095 TI - Dosage of trimipramine. PMID- 6929096 TI - Trimipramine in the treatment of duodenal ulcer. A multicenter, open study. AB - Sixty patients with endoscopically confirmed duodenal ulcers were treated with 50 mg of trimipramine daily. After the end of the treatment 45 patients showed healed ulcers. Ulcer healing was not related to serum concentration of trimipramine, but seemed to be influenced by smoking habits and duration of the total and actual disease history. PMID- 6929098 TI - Frequency of relapses in duodenal ulcer patients treated with cimetidine during symptomatic periods. PMID- 6929097 TI - Trimipramine and duodenal ulcer. AB - The gastric acid secretion, fasting serum gastrin and serum concentration of trimipramine were studied in 20 patients with duodenal ulcer during a 6 weeks treatment with trimipramine. Ulcer healing was examined endoscopically. In the group of 11 patients with healed ulcers the gastric acid secretion decreased significantly at 3 and 6 weeks in contrast to the 9 patients in whom ulcers did not heal, indicating a different antisecretory response in the two groups. The serum concentration of trimipramine was similar in both groups during treatment. Possible mechanisms of action of trimipramine in peptic ulcer disease and problems concerning clinical response and dose are discussed. PMID- 6929099 TI - Symposium on metronidazole against anaerobic infections. Solstrand Fjordhotel, 2 3 March, 1979. PMID- 6929100 TI - Symposium on chemotherapeutic prophylaxis in colo-rectal surgery. PMID- 6929101 TI - Susceptibility of 4410 clinical isolates to doxycycline. AB - In an 1100-bed hospital where doxycycline has been widely used, the susceptibility to doxycycline of 4410 clinical isolates was examined. Ninety-one and 80.8 per cent of the Staphylococcus aureus and Haemophilus influenzae strains, respectively, were susceptible to 1 mg doxycycline/l. Seventy-four per cent of the Escherichia coli and 81.7 per cent of the Klebsiella strains were inhibited by 4 mg/l. The Enterobacter and Enterococcus strains were less susceptible. Nearly all Proteus mirabilis isolates were resistant. The results are comparable to those of other studies. PMID- 6929102 TI - Infection prophylaxis with doxycycline in colorectal surgery. A preliminary report. PMID- 6929103 TI - The leucocyte alkaline phosphatase activity in mature neutrophils of different ages. AB - The marrow myeloid precursor cells of a haematologically normal patient were labelled by intravenous injection of tritiated thymidine. Young labelled segmented neutrophils were then released from the marrow into the blood by an injection of cortisol. These PMN had a significantly lower LAP activity than the older blood neutrophils. It is shown that within the morphologic boundaries of the segmented PMN, the cells are still in different stages of cytoplasmic maturation. In addition, labelled and unlabelled neutrophils showed a linear and parallel increase of LAP activity during the 24 h following cortisol injection. This observation suggests that the neutrophil prematurely released in the blood can mature into normal LAP=PMN and more generally that LAP activity of a blood neutrophil increases with time. PMID- 6929104 TI - The Will E. Donahoe Memorial Lecture. Pediatric education: past, present, future. PMID- 6929105 TI - Sixty-seven year old caucasian male with hemoptysis and right upper lobe infiltrate of several weeks duration. PMID- 6929106 TI - Radiation pneumonitis and fibrosis following radiation for carcinoma of the breast. PMID- 6929107 TI - Forty-two year old female with sudden onset of abdominal pain. PMID- 6929108 TI - A unique case of anorexia nervosa: a review paper. PMID- 6929109 TI - Gene transfer given a new twist. PMID- 6929110 TI - Cloning gold rush turns basic biology into big business. PMID- 6929111 TI - Mapping bone cancer death rates in Pennsylvania counties. PMID- 6929112 TI - Acute lymphocytic leukaemia terminating in malignant histiocytosis. A case report and literature review. AB - A 5-year-old Black girl with acute lymphatic leukaemia died after a short illness during which haematological remission was induced with standard chemotherapeutic agents. At autopsy an unexpected finding was involvement of the spleen, lymph nodes, bone marrow and liver by malignant histiocytosis (MH). There was also evidence of residual leukaemia. A review of the literature revealed 11 other cases with a similar association of leukaemia preceding MH; in 8 of these the leukaemia was of the acute lymphatic type, in 2 of the monocytic type and in 1 of an unusual atypical large lymphoid cell type. The clinico-pathological features of these cases are reviewed. PMID- 6929113 TI - Random segretation of multiple genetic markers from CHO-CHO hybrids: evidence for random distribution of functional hemizygosity in the genome. AB - The linkage relationship between various recessive markers isolated in Chinese hamster ovary (CHO) cells has been investigated. For such studies, multiple recessive markers conferring resistance to various drugs, e.g., resistance to emetine (Emtr), thioguanine (Thgr), azaadenine (Azar), phytohemagglutinin (Phar), diphtheria toxin (Dipr), toyocamycin (Toyr), aminopterin (Amnr), and methylglyoxalbisguanyl hydrazone (Mbgr), were introduced into CHO lines by selecting successively for one drug at a time. Hybrids were constructed between the multiply marked lines and the sensitive cells, and segregation frequencies for the various markers, singly and in different pairs, were examined. Results of such studies show that of the recessive markers examined, none cosegregated from the hybrid cells. The independent segregation of the X-chromosome-linked Thgr and of the rest of the markers indicates that none of these other mutations are located on the X chromosome. These results also provide strong suggestive evidence that functional hemizygosity in CHO cells is not restricted to one or a few chromosomal regions, but rather appears to be widespread. PMID- 6929114 TI - X-linked control of globin mRNA and hemoglobin production in erythroleukemia lymphoma cell hybrids. AB - In somatic cell hybrids formed by the fusion of mouse erythroleukemic cells with cultured mouse lymphoma cells, retention of the X chromosome donated by the lymphoma parent is correlated with inhibition of hemoglobin accumulation in response to dimethyl sulfoxide. The inhibition of hemoglobin production was due to an inhibition of globin mRNA accumulation. Heme can partially overcome the effects of the lymphoma X chromosome and induce globin mRNA and hemoglobin accumulation in the dimethylsulfoxide-treated hybrid cells. The data suggests that the X chromosome contributed by the lymphoma cells inhibits hemoglobin production by inhibiting both inducible globin mRNA accumulation as well as inducible heme biosynthesis, most likely at a step after the formation of delta aminolevulinic acid. The properties of erythroleukemia x lymphoma cell hybrids are compared with those of a series of erythroleukemia x bone marrow cell hybrids. The data indicate the possibility of multiply loci on the X chromosome capable of regulating the expression of erythroid characteristics. PMID- 6929115 TI - [Tissue reparative regeneration processes in the hard palate after surgical interventions]. PMID- 6929116 TI - [Seduxen premedication in stomatological practice]. PMID- 6929117 TI - [Correlation of the secretory activity of the salivary glands and of the gastric fundic glands in duodenal peptic ulcer]. PMID- 6929118 TI - [Nasotracheal intubation using a fiber bronchoscope in maxillofacial operations]. PMID- 6929119 TI - [Clinical aspects and treatment of septic shock in stomatological patients]. PMID- 6929120 TI - [Orthopedic surgical method of treating deformations of the central area of the facial skeleton]. PMID- 6929121 TI - [Problems of ideological political education work to the forefront]. PMID- 6929122 TI - [Silver uptake in the saliva of persons wearing metal-coated plastic prostheses]. PMID- 6929124 TI - [External respiration in children with maxillodental system anomalies and cleft palate]. PMID- 6929123 TI - [Regional circulatory dynamics in children during pentrane (ingalan) combined anesthesia in stomatological interventions]. PMID- 6929125 TI - [Methodology for the clinical use of amalgam]. PMID- 6929126 TI - [Yeast-like fungi and Leptotrichia of the oral mucosa]. PMID- 6929127 TI - [X-ray data on the state of the periapical tissues in pulpitis]. PMID- 6929128 TI - [Experience with extrafocal compression osteosynthesis in treating mandibular fractures]. PMID- 6929129 TI - [Rhabdomyosarcoma of the palate]. PMID- 6929130 TI - [Experience in using an iodine chloride solution for treating parodontosis]. PMID- 6929131 TI - [Scientific cooperation of the Central Research Institute of Stomatology (USSR) and the Erfurt Medical Academy (GDR)]. PMID- 6929132 TI - [Histological characteristics of the rests of Malassez in the human periodontium]. PMID- 6929134 TI - [Experimental evaluation of the cariostatic effectiveness of tooth pastes and elixirs containing aminofluorides]. PMID- 6929133 TI - [Effect of local-acting cariostatic prophylactic agents on the microflora of the deposit on the teeth]. PMID- 6929135 TI - [Calcium transport across the rat placenta with fluorine intake with the drinking water]. PMID- 6929136 TI - [Results of many years' use of fluorides for the group prevention of dental caries]. PMID- 6929137 TI - ["Gamma" stock for preparing porcelain dental crowns]. PMID- 6929138 TI - [Morphological and histoautoradiographic study of tooth eruption]. PMID- 6929139 TI - Helper-independent and replication-defective erythroblastosis-inducing viruses contained within anemia-inducing Friend virus complex (FV-A). PMID- 6929140 TI - [Immunochemical studies of human cathepsin D]. AB - Rabbit antiserum against human liver cathepsin D was raised. The antiserum did not cross-react with cathepsins D from tissues of other species (bovine liver, bovine spleen, chicken liver). The study of cathepsins D isolated from human pathologically altered tissues showed that cathepsins from kidney malignant tumor and from myeloleucosis-induced spleen tumor were immunologically identical to the enzyme from normal liver. Cathepsins from liposarcoma and uterine myoma were characterized by partial identity with the enzyme from normal liver. Cathepsins D isolated from various human livers exhibited individual quantitative differences in antigenic properties, a fact to be taken into account in development of an immunochemical method for identification of cathepsin D. The low immunogenicity of human cathepsin D for rabbits and inadequate suitability of these animals for raising appropriate antisera was also considered. PMID- 6929141 TI - Ureterocutaneous fistula following nephrectomy. PMID- 6929142 TI - Sports medicine and the adolescent athlete. PMID- 6929144 TI - New poison control system based in Charleston. PMID- 6929143 TI - The human factor. PMID- 6929145 TI - An outbreak of shigellosis in Kanawha County, West Virginia. PMID- 6929146 TI - Primary squamous cell carcinoma of the endometrium: a case report. PMID- 6929147 TI - Political choice. PMID- 6929148 TI - Solitary testicular metastasis from renal cell carcinoma and concomitant primary adenocarcinoma of the prostate. PMID- 6929149 TI - The value of cytology in the diagnosis of endometrial pathology. PMID- 6929150 TI - Cytoenzymologic investigations on carcinomas of the cervix uteri. AB - A study was carried out on 85 patients with lesions of the cervix uteri: 45 carcinomas and 40 dysplasias. A large battery of cytoenzymatic tests was used to determine their potential value in the diagnosis of carcinomas. An increase of LDH, G6PDH, 6PGDH and NADH2-TR activities and a loss of alpha-GP-ase I activity were demonstrated in malignant cells. It is suggested that the cytoenzymologic techniques may offer help in the distinction between normal, dyskaryotic and malignant cells of vaginal fluid. In individual patients these techniques are useful in understanding the evolution of dysplastic lesions and in the diagnosis of carcinoma. These techniques, however, cannot be used as a general screening test for malignancy. PMID- 6929151 TI - Cerebrospinal fluid involvement by malignant histiocytosis. PMID- 6929152 TI - Microfilaria in the endometrial smear. PMID- 6929153 TI - Ewing's sarcoma: cytology of large cell type. PMID- 6929154 TI - Diagnostic cytology seminar. PMID- 6929155 TI - [Plasma thrombopoietic activity in myeloblastic and myelocytic leukemia]. PMID- 6929157 TI - Numerical expression of paternity test results using predetermined indexes. AB - Relative chance of paternity (RCP) is a numerical expression used to indicate either paternity (near 100%) or nonpaternity (0% or close to 0%). RCP is derived by converting the paternity index (PI) to a percentage, RCP = PI/(PI+1). PI represents the chance that the alleged father is or is not the father, and is expressed as a number for a given phenotype combination of the mother-child alleged-father trio. These PI values have been determined and are listed in several tables. Thus, one can find in these tables the individual PI value for each genetic marker system for a given trio, multiply the numbers, and convert the combined PI value into RCP. In this way, a qualitative and quantitative report of a paternity testing can be readily derived. PMID- 6929156 TI - Necrotizing myelopathy associated with acute lymphoblastic leukemia. Case report and review of literature. AB - The clinico-pathological findings are reported of a 16-year-old boy with acute lymphoblastic leukemia who during chemotherapy which included intrathecal Methotrexate developed a transverse cord lesion 5 months before death. Autopsy revealed necrotizing myelopathy of the T8--T10 segments and moderate lymphoblastic infiltration of the cerebrospinal meninges and spinal nerve roots. Neither parenchymal infiltration nor vascular lesions were found. The pathogenesis of this rare lesion associated with acute lymphoblastic leukemia remains obscure. PMID- 6929158 TI - Apparent discharge of cell fragments from blasts cells in acute leukemia. An ultrastructural study. AB - In the blast cells of three patients who had leukemia, formation of small surface blebs and the apparent discharge of small cytoplasmic fragments were observed by light and electron microscopy. An ultrastructural study showed that they consisted of either double membrane-lined vacuoles or solid cytoplasmic fragments. The exact cause of this phenomenon is not known, but may be related to the complex alterations in the surfaces of malignant cells. PMID- 6929159 TI - Many changes in JCAH standards affect pharmacy department. PMID- 6929160 TI - Mandibular sagittal subapical osteotomy: a case study. AB - A case involving mandibular sagittal subapical osteotomy has been demonstrated. When the patient presented initially I was unaware of this particular operation. Prior to surgical intervention there was significant improvement in the previously abused lower labial tissues, but an impasse developed with respect to limiting treatment to orthodontic means alone. Along with lower tissue recovery, unexpected benefits resulted, namely, bite opening, establishment of excellent occlusion, and dramatic facial improvement. Etiologically, it would appear that apparently a severe forward rotational growth pattern with muscular imbalance had produced an adverse facial configuration in an otherwise reasonable craniofacial complex. As a result of this experience, it was brought home more conclusively than ever that it is well to realize before entering into presumably minor or compromise treatment procedures for many orthodontic problems, particularly in advanced skeletal malocclusions, that the possibility of orthognathic surgery exists and one would be wise to explore thoroughly and advise those involved of such possibilities before becoming clinically involved. PMID- 6929162 TI - A cephalometric appraisal of xeroradiography. AB - The literature on the physics, the radiation hazard, and the current medicodental applications of xeroradiography is reviewed. A study is presented on estimating the effect of a xeroradiographic technique on the degree of inter- and intraobserver error in cephalometric landmark identification, as compared to a radiographic technique. This study involved identification by four observers of sixteen cephalometric landmarks on twelve xeroradiographs and twelve radiographs, on two separate occasions. The conclusions are that neither technique provided a significant reduction in interobserver differences. However, for eight of the thirty-two variables (nasion's Y axis, portion's X and Y axes, basion's X axis, Bolton point's X axis, anterior nasal spine's X axis, menton's Y axis, and the tip of the nose's X axis), as opposed to two (basion's Y axis and gonion's Y axis), xeroradiography produced a significant reduction in intraobserver error in comparison to radiography. PMID- 6929161 TI - An electron microscopic study of attachments between periodontal fibers and bone during alveolar remodeling. AB - Three types of periodontal membrane-to-bone attachments are described for remodeling surfaces of the bony alveolar wall. An adhesive type, which is the most widespread means for tooth anchorage on resorptive bone surfaces during active tooth movements, involves the following histogenic steps: A layer of ground substance is first deposited by fibroblast-like cells on the naked surface of recently resorbed bone. As this continues, new precollagen and the dissociated ends of collagenous fibrils become embedded in the accumulating ground substance, and these fibrils in turn become joined to intact collagenous fibrils, blending with the remainder of the periodontal stroma. Such adhesive attachments continuously form and re-form as the resorption front proceeds. A continuous type of attachment also occurs on resorptive bone surfaces in which some (not all) bone matrix fibrils survive the resorptive process. These former bone fibrils become incorporated into the periodontal membrane and are continuous between the bone matrix and the stroma of the contiguous periodontal membrane. An intermediate type of attachment also occurs and is primarily an adhesive attachment that also contains a scattering of fibrils which are continuous from the bone matrix across the resorptive bone surface into the fibrous matrix of the periodontal membrane. PMID- 6929163 TI - Behavioristic technique or oral hygiene--an update. AB - Two previous articles describing a behavioristic approach to oral hygiene for orthodontic patients have been presented by the author. The present article evaluates a key feature of the latter study which used an aversive conditioner for patients who came to the office with loose bands and displayed poor oral hygiene. The aversive conditioner was effective in reducing poor oral hygiene during office visits but had no effect in reducing the incidence of loose bands. The timing of aversive stimulus is probably responsible for success with the oral hygiene training and also for the failure to reduce the number of loose bands. PMID- 6929164 TI - The art in orthodontics. PMID- 6929165 TI - Biennial size norms of eight measures of the temporal bone from four to twenty years of age. PMID- 6929166 TI - Case report. PMID- 6929167 TI - Late third molar genesis: its significance in orthodontic treatment. AB - (1) Third molar genesis may occur up to the age of sixteen years, although the possibility of their appearance after the age of twelve years is reduced. (2) When third molar genesis is delayed beyond the age of ten years, the possibility of all four third molars developing is reduced by about fifty percent. (3) The intraindividual variability in stage of development of third molars increase when genesis is delayed beyond ten years of age. (4) There is no significant difference in size of early and late developing third molars. PMID- 6929168 TI - Effects of intrusive forces upon the microvasculature of the dental pulp. AB - This in vivo study has demonstrated in rats that the nutritional blood flow of the pulp may be compromised after application of an intrusive orthodontic force. The results of this study and the findings of other investigators suggest that an in depth study analyzing the relationship between pulpal viability and orthodontic tooth movement may be indicated. PMID- 6929169 TI - The prediction of facial growth. AB - In the two contrasting malocclusions, the open bite and the deep overbite, statistically significant differences are shown in the anterior, middle and posterior endocranial regions. In open bite there is an association between the lower face height and the size of the anterior, middle and posterior cranial regions, but in deep overbite the associations between face height and the endocranial size are less strong. These and other associations if brougth together in a multiple regression analysis may prove useful in prognosticating the final face height in the growing child, particularly in the open-bite case. PMID- 6929170 TI - Effects of stress relief on the mechanical properties of orthodontic wire loops. PMID- 6929171 TI - Preventive and interceptive orthodontics: a strong theory proves weak in practice. PMID- 6929172 TI - Fiberotomy and reproximation without lower retention, nine years in retrospect: part I. PMID- 6929173 TI - Remodeling reversals in anterior parts of the human mandible and maxilla. PMID- 6929174 TI - JCAH emergency service standards: the Sisyphean struggle continues. PMID- 6929175 TI - [CNS prophylaxis in acute lymphoblastic leukemia (author's transl)]. AB - Results of CNS prophylaxis of 43 LLA children are studied. Prognostic characteristics of the group, follow-up time, and controls made are reported. Prophylaxis was made with intrathecal methotrexate associated to craneal (24 patients) or craneospinal irradiation. There was a 13% of meningosis between three and 27 months of the first complete remission. There were no differences of effectiveness between the two methods of treatment. The side effects were mild. Fifty five percent of patients showed fever, and vomits after intrathecal methotrexate injections, and 16% somnolence postradiotherapy syndrome. There were two more severe complications, one sepsis and one necrotizing leukoencephalopathy. PMID- 6929176 TI - The changing radiographic appearance of osteogenic sarcoma. PMID- 6929177 TI - Lipoblastomatosis: report of a case. PMID- 6929178 TI - The future already happened. PMID- 6929179 TI - The geometric analysis of mandibular dental arch form. PMID- 6929180 TI - [Plasmid resistance of the enterobacteria isolated in intestinal disorders in children]. AB - Resistance to antibiotics and sulfanilamides was determined in enterobacteria (E. coli, Pr. mirabilis, Sh. sonnei, Sh. flexneri) isolated from children with intestinal disorders. Elimination of the resistance determinants in polyresistant strains, conjugation of R plasmids (75 per cent in Pr. mirabilis, 70 per cent in E. coli, 78 per cent in Sh. sonnei, 69 per cent in Sh. flexneri), mobilization of nonconjugative plasmids on triple crossing and capacity of R plasmids for repression of the F-factor functions were studied. The data of the study are evident of the plasmid background in enterobacteria isolated from children with intestinal disorders and confirm the plasmid nature of the resistance in the predominating number of the strains. It is suggested that Proteus plays a significant role in the prevalence of plasmid resistance among enterobacteria. PMID- 6929181 TI - Abdominosacral approach for retrorectal tumors. AB - The relative rarity and anatomical position of retrorectal tumors may lead to difficulty in diagnosis and surgical treatment. The clinical features and management of 20 such tumors (chordoma 8, neurilemmoma 3, teratoma 3, hemangiopericytoma 1, chondrosarcoma 1, osteosarcoma 1, dermoid 1, lipoma 1, and undifferentiated sarcoma 1) have therefore been reviewed. Low back or sacral pain was present in 18 patients and, although all tumors were palpable on rectal examination, pain had been present for a median of 12 months before diagnosis. Mean tumor size was 9.4 cm (range: 2.5-17 cm). Sacral bone destruction was demonstrated radiographically in all chordomas and three sarcomas, but in none of the benign tumors. Three patients had undergone previous partial removal of their tumors. Surgical resection was carried out using a combined abdominal and transsacral approach in 13, a transsacral approach in the right lateral position in four and transabdominally in three. There was one operative death following secondary operation for chbrdoma. Four of 12 patients with malignant tumors are alive and well at seven months to eight years. One died of a myocardial infarct without recurrence at 11 years. For small benign tumors, the right lateral position permits maximal flexibility for resection either by the transsacral, transabdominal or a combined approach. For bulky or malignant tumors, a combined abdominal transsacral approach in the right lateral position permits vascular control and provides good exposure for protection of vital structures and wide resection. PMID- 6929182 TI - The fine structure of epithelial cells in normal and pathological buccal mucosa. II. Colloid body formation. AB - Seven cases of the erosive type of lichen planus, as well as normal tissue, were studied with the optical and electron microscope. The study was concerned with the distribution and formation of colloid bodies. These bodies were located at the epithelial-proprial junctions and occasionally inter-epithelially. They were seldom larger than basal epithelial cells and were macrophages which contained fragments of phagocytosed epithelial cells. They probably correspond to cytoid bodies which have a similar size and a similar distribution. PMID- 6929184 TI - Why is it so? PMID- 6929183 TI - Comparison of mesiodistal crown diameters of the deciduous and permanent teeth in Australian aboriginals. AB - Mesiodistal crown diameters of corresponding deciduous and permanent teeth were compared in 106 male and 66 female Aboriginal subjects from Yuendumu in the Northern Territory of Australia. On average, the size relationships were similar to those reported for Caucasoid groups but there was considerable variation between subjects, particularly in the deciduous first molar--permanent first premolar comparison. PMID- 6929185 TI - Dental health education. PMID- 6929186 TI - Therapeutics Advisory Committee. Prevention of infective endocarditis associated with dental treatment and dental disease. Report of the Committee. PMID- 6929187 TI - The static creep of amalgams from fifteen alloys. AB - The static creep of amalgams prepared from fifteen conventional Ag3Sn and higher copper alloys was investigated one week after packing. The rate at which the different alloys develop resistance to creep was compared by testing amalgams at a number of times other than one week. A microfine lathe-cut alloy possesses the highest static creep and the single melt high copper type of alloy the lowest. An admixed high copper group of alloys possesses static creep similar to the silver copper dispersed alloys. The rate at which amalgam develops a resistance to creep is dependent on the alloy type. PMID- 6929188 TI - Effects of methotrexate esters and other lipophilic antifolates on methotrexate resistant human leukemic lymphoblasts. PMID- 6929189 TI - [The nitroblue tetrazolium activated test in the study of granulocytic function. Proposed methodology]. AB - It was reported a combined methodological proposal to test simultaneously activated-NBT and phagocytic index (PI) assay using zymosan particles. Such a method allowed to evaluate these two steps of the phagocytic process in the same cellular population. Comparable results were obtained performing the two methods separately. PMID- 6929191 TI - Symposium on infections in the elderly: characteristics and treatment. Section on Geriatric Medicine of the New York Academy of Medicine with the American Geriatric Society. PMID- 6929190 TI - Low IgG or IgA: a further indicator of poor prognosis in childhood acute lymphoblastic leukaemia. PMID- 6929192 TI - Infections in the elderly: characteristics and treatment. PMID- 6929193 TI - Use of antibiotics in the elderly. PMID- 6929195 TI - Ancillary tests for the diagnosis of retinoblastoma. PMID- 6929194 TI - Urinary tract infections in the elderly. PMID- 6929197 TI - Genetic, growth, and reproductive effects of microwave radiation. PMID- 6929196 TI - Cardiovascular effects of glycopyrrolate and belladonna derivatives in obstetric patients. PMID- 6929199 TI - Cerebral protection by barbiturates and loop diuretics in head trauma: possible modes of action. PMID- 6929200 TI - Low humidity and damage to tracheal mucosa. PMID- 6929198 TI - Paget's disease of bone. PMID- 6929202 TI - Statement on amebiasis. The Committee on Public Health, The New York Academy of Medicine. PMID- 6929203 TI - Symposium on the care of private patients in teaching hospitals: the role of residents. Committee on Medical Education, The New York Academy of Medicine. PMID- 6929201 TI - The management of open and complex fractures of the tibia. PMID- 6929205 TI - Perspective of the internist. PMID- 6929204 TI - An academically organized private medical service: structure, function, problems, and lessons. PMID- 6929206 TI - Perspective of the surgeon. PMID- 6929207 TI - Private patient care and residency training: a surgeon's viewpoint. PMID- 6929209 TI - Care of private patients in teaching hospitals: a perspective of the referring physician. PMID- 6929210 TI - The role of private patients. PMID- 6929208 TI - A study of the role of private patients in surgical training programs: a resident's viewpoint. PMID- 6929211 TI - The care of private patients in teaching hospitals: legal implications. PMID- 6929213 TI - Perspective of the hospital administrator and the third party payer. PMID- 6929212 TI - Ghost surgery. PMID- 6929215 TI - Role of metastatectomy without chemotherapy in the management of osteosarcoma in children. AB - In a series of 18 consecutive non metastatic osteosarcoma patients, metastases developed in 12 and successful metastatectomies could be performed in 6. No adjuvant chemotherapy was given. Four of these 6 patients survived. The importance of length of disease-free survival is described. Radiotherapy and chemotherapy as adjuvants to prevent or postpone the development of metastases are mentioned and an EORTC-SIOP trial on this subject is briefly discussed. PMID- 6929214 TI - High rate of long-term survivals in AML treated by chemotherapy and androgenotherapy: a pilot study. AB - An unexpectedly high rate of long-term survivors in acute myeloid leukemia (AML) has been observed in a group of patients who achieved a first complete remission (CR) after induction of a therapeutic regimen including daunorubidomycine, vincristine, prednisone and stanozolol, and anabolizing steroid. The rate of CR was 52%. Maintenance therapy was very simple and the only association with stanozolol during this period suggested to us that an androgen, at low dosages, might be responsible for the unusual long-term survival time (45 months with a 95% confidence limit from 30 to 86 months). On the basis of our first observation, high dosages of the androgen were used during the induction phase of treatment but failed to demonstrate any advantage when associated with a drug regimen, including cytosine arabinoside (ARA-C). The reevaluation of each parameter for our group of patients did not allow selection of patients in terms of their age or the hematologic data obtained at presentation. Effects of androgen on the socalled normal hemopoietic cells and on the leukemic cells are discussed, particularly the possible antagonistic effect with ARA-C. A prospective statement is made concerning the possible condition of the prolongation of the complete remission in AML according to some experimental data which enforce the stimulative activity of androgen on the myeloid proliferation. PMID- 6929216 TI - Ataxia-telangiectasia and acute lymphoblastic leukemia. AB - Lymphoreticular malignancies occur frequently in association with ataxia telangiectasia (A-T). This paper presents one new case and reviews all 19 known cases of A-T and acute lymphoblastic leukemia (ALL). The leukemia is associated with poor prognostic factors: male sex, older age, high white blood cell count, and T or B-cells. There have been no long-term survivors; recently, prolonged remissions have been attained. These patients appear to be at special risk for infections secondary to the immunodeficient state associated with A-T and ALL therapy. A heightened sensitivity to the neurotoxic effects of vinca alkaloids and central nervous system irradiation seems to be present. PMID- 6929217 TI - Long-term survival in acute leukemia in Japan. A study of 304 cases. AB - In a national survey of five-year survivors with acute leukemia, 233 of 304 cases were children under 14 years of age and 71 were adults. There were 107 myeloblastic, 10 promyelocytic, 142 lymphocytic, and 37 undifferentiated leukemias, Forty-five cases at age 3 represented the peak. These long-term survivors have shown a yearly increase in number. In 1972, the number of childhood ALL cases reached 38 with no great changes in ANLL cases. With respect to prognosis among long-term survivors, it seemed that neither type of leukemia nor age at diagnosis were factors influencing the future survival. CNS relapse occurring before the third year was an unfavorable complication for a prognosis beyond five years. Only 8 patients died of leukemia among 155 patients who reached five years in their initial complete remission; 49 of 90 patients who had relapse within five years after diagnosis died of leukemia. From these findings, it seems very important to follow patients for five years in their initial complete remission. PMID- 6929219 TI - A comparative cytogenetic study of melphalan-sensitive and -resistant murine L1210 leukemia cells. AB - A cytogenetic analysis of melphalan-sensitive and -resistant murine L1210 leukemia cells maintained in vivo indicated that the drug-resistant tumor had a modal number of 40 chromosomes while the sensitive tumor possessed a mode of 41 chromosomes. Two marker chromosomes were present in both the sensitive and the resistant tumors. One was of medium length with secondary constrictions, and the other was a minute chromosome. A single in vitro exposure of the sensitive tumor cells to a cytotoxic concentration of melphalan was not accompanied by a change in modal number but resulted in chromatid exchange. No alterations were found in resistant tumor cells which were exposed to the same drug concentration. However, exposure of resistant tumor cells to higher doses of melphalan resulted in chromatid breaks, chromatid gaps and the formation of acentric chromosomes. The resistant tumor, transplanted once without drug injection, maintained a sharp mode of 40 chromosomes. PMID- 6929218 TI - A second chance. PMID- 6929220 TI - Effect of maturation on the response of human promyelocytic leukemia cells (HL 60) to the tumor promoter 12-o-tetradecanolyphorbol-13-acetate. PMID- 6929221 TI - Nonspecific cross-reacting antigen in normal and leukemic myeloid cells and serum of leukemic patients. PMID- 6929223 TI - Effects of the topical application of mutanase on rat caries. PMID- 6929222 TI - Variable ratios of lactate and malate dehydrogenase-like enzyme activities and LDH isoenzyme distribution in the odontoblast-predentine region of intact and carious human teeth. PMID- 6929225 TI - Dental caries and the concentration of aluminium and strontium in enamel. PMID- 6929226 TI - [Prevention of CNS leukemia in children with acute lymphoblastic leukemia]. PMID- 6929224 TI - Cariogenicity of topically applied sugar substitutes in rats under restricted feeding conditions. PMID- 6929227 TI - A comparison of microtia and temporal bone anomalies in hemifacial microsomia and mandibulofacial dysostosis. AB - A number of entities can be categorized as otocraniofacial syndromes. New clinical and laboratory studies have demonstrated predictable patterns of occurrence, distinct anatomic interrelationships, separate genetic predispositions, and animal models of the varied embryogeneses. These investigations have allowed clinical separation of first and second branchial arch anomalies into syndromes of hemifacial microsomia and mandibulofacial dysostosis. The present study has established a relationship between the severity of the microtic auricle and middle ear malformation in those syndromes. Middle ear deformities, while present in both, are more severe when associated with mandibulofacial dysostosis. PMID- 6929228 TI - Hemifacial microsomia: priorities and sequence of comprehensive otologic management. AB - Hemifacial microsomia is evidenced by the clinical spectrum of microtia, mandibular deformities, and middle ear malformations. This constellation of defects suggests that the most efficacious treatment will be multidisciplinary management, which includes the otolaryngologist, audiologist, plastic surgeon, and temporal bone radiologist. In the past, microtia--the most clinically apparent malformation--usually has been studied and treated with respect to the area of special interest of the investigator, whether from an otologic, reconstructive, or radiologic perspective. Newer management, however, utilizes the combined skills of the clinical and behavioral disciplines in the treatment of the microtic auricle, associated middle ear pathology, and hearing loss. Such multidisciplined approach, commencing during the first year of life, is deemed advisable to cope with the severe unilateral or bilateral hearing loss which may lead to potentially serious sensory deprivation and impede adequate language development in these children. PMID- 6929230 TI - Oral adhesions associated with cleft lip and palate and lip fistulae. AB - Three cases of congenital strand-like adhesions between the upper and lower gum pads associated with cleft lip and palate and lower lip fistulae are reported. A consideration of the literature would suggest that this may represent an autosomal dominant trait with variable penetrance and expressivity though a positive family history was found in only one case. The adhesions may have arisen by persistence of the oropharyngeal membrane or anomalous fusion of adjacent epithelial surfaces, the latter seeming rather more likely in the present series. The clinical implications are discussed. PMID- 6929231 TI - Velopharyngeal insufficiency in the facio-auriculo-vertebral malformation complex. AB - Twenty-two patients with the Facio-Auriculo-Vertebral Malformation Complex (hemifacial microsomia) were examined with multi-view videofluoroscopy and nasopharyngoscopy at rest and during speech. Fifty-five per cent of the subjects had velopharyngeal insufficiency (VPI) and hypernasal speech. Only two of these 12 subjects had cleft palate. VPI was related to structural and physiological asymmetry of the pharynx. No relationship was found between the severity of facial malformation and the presence of VPI. PMID- 6929229 TI - Craniofacial morphology in twins discordant for cleft lip and/or palate. AB - The craniofacial structure in 44 pairs of like-sexed twins discordant for cleft of the lip and/or palate was investigated using lateral cephalometric radiographs. While only a slight rotation of the mandible was evident in the twins having cleft lip, more extensive rotation of the mandible was found in the twins discordant for unilateral cleft lip and palate. Larger, though generally non-significant, changes were recorded for the twins affected with bilateral cleft lip and palate. In the twins discordant for cleft palate only, statistically significant differences were found for maxillary length, mandibular corpus length, cranial base flexure (Ar-S-Na), horizontal and vertical positioning of the posterior maxilla, mandibular plane angle, and gonial angle. Although the effect of sex on the within twin differences was not statistically significant, the effects of age, zygosity, and cleft type were. It is suggested that there is an increasing degree of dysmorphism, with increasing severity of clefting from cleft lip only to bilateral cleft lip palate. PMID- 6929232 TI - A modified tongue-lip adhesion for Pierre Robin anomalad. AB - A modified tongue-lip adhesion for Pierre Robin anomalad, based on the work of Douglas (1946), Routledge (1960) and Randall (1977) is described. Modifications include placement of the incision and stripping of the geniglossus muscles from the mandible. Conservative non-operative management is successful for most patients, but an adequate surgical adhesion avoids tracheostomy when more active treatment is needed. PMID- 6929233 TI - Nasal obstruction as a complication of pharyngeal flap surgery. AB - In a series of 85 patients who had pharyngeal flap surgery at Indiana University Medical Center, We found an unusually high incidence of hyponasality with total or near total nasal obstruction. The nasal obstruction was often occult, detected only after careful questioning and examination. Nasal obstruction was associated with peri-operative infection or micrognathia as in the Pierre Robin Anomalad. Flap division or port revision yielded a significant relief of the nasal obstruction and achievement of normal nasal balance. PMID- 6929234 TI - Movement of the cleft maxilla in infants relative to the frontal bone. A roentgen stereophotogrammetric study with the aid of metallic implants. AB - Four implants (tantalum balls 0.5 mm in diameter) were inserted in the frontal bone, and three implants (tantalum pins 1.5 x 0.5 mm) were inserted in each lateral segment of the cleft maxilla of ten infants aged 13 to 42 months. Motion of the maxillary segments was studied relative to the frontal bone by means of roentgen stereophotogrammetry during observation periods from 371 to 868 days. The results were presented by means of computer drawings of the implant triangles projected on the three cardinal planes. With this technique, movement of the maxillary segments could be visualized with a high degree of accuracy. No pattern of movement related to time or type of surgery, to type of cleft (UCLP/BCLP), or to cleft or non-cleft segment could be found. PMID- 6929236 TI - Velopharyngeal valving. PMID- 6929235 TI - Pre-school articulation test to assess velopharyngeal competency: normative data. AB - The purpose of this work was to develop an articulation test which would be discriminating in the determination of velopharyngeal incompetency in young children. From 50 words containing the /p/ and /b/ sounds, normative data for children approximately 3 1/2 years of age were collected. From the responses of these children, 25 words were selected for a base test. Validity of the test is currently being determined. PMID- 6929237 TI - Acute non-lymphocytic leukaemia. PMID- 6929239 TI - Osteosarcoma cells in tissue culture: II. Characterization and localization of alkaline phosphatase activity. AB - Although elevated alkaline phosphatase levels in osteosarcoma have been shown to be related to prognosis, the functional significance is unclear. Human osteosarcoma cells in tissue culture retain detectable amounts of alkaline phosphatase activity. In this study the specific activity of that enzyme was compared in 13 osteosarcoma tissue culture lines and 13 normal skin fibroblast lines derived from the same patients. Osteosarcoma cells had significantly higher baseline alkaline phosphatase levels and could be stimulated with hydrocortisone to produce more enzymatic activity than the fibroblast lines. Activity was localized ultracytochemically to the cell membrane and to many small intracellular vesicles in stimulated osteosarcoma cells. These observations aid in the differentiation of osteosarcoma and fibroblast lines in tissue culture and suggest an association between elevated alkaline phosphatase levels and metabolic abnormalities in patients with osteosarcoma. PMID- 6929238 TI - Replacement of the proximal humerus with a ceramic prosthesis: a preliminary report. AB - Insertion of a multicomponent ceramic prosthesis with extracortical fixation to the conically reamed shaft of the humerus was performed in 7 patients after resection of 4 malignant and 3 benign tumors of the proximal humerus. The length of the replacement ranged from 9 to 18 cm. Fixation was secure in all but one patient, who sustained a fracture through the proximal humerus. Subluxation occurred in 3 patients but posed no difficulty, except in one patient who required revision for a dislocation. Functionally, little active motion is achieved, but the implant provides a spacer to permit efficient use of the hand and elbow. No patient has had local recurrence of the tumor. One patient died one year postoperatively from an unrelated second primary cancer. Although the preliminary results are encouraging, further investigations are necessary on the mechanical aspects of the cone fixation principle and of the techniques of shoulder muscle reconstruction to improve the function of the prosthetic joint. PMID- 6929240 TI - Guide to epidemiology and diagnosis of oral mucosal diseases and conditions. World Health Organization. PMID- 6929241 TI - Dental caries in a group of 20-year-olds after previous participation in public child dental health services in Copenhagen, Denmark. AB - The present study was undertaken to investigate the prevalence of dental caries in a group of 20-year-olds who had previously participated in Public Child Dental Health Services. Dental caries was related to social status and preventive vists to the private dentist after termination of school. The study population comprised 389 persons aged 20, out of which 313 (80.5%) were examined clinically and radiographically by one dentist according to standardized criteria. Mean DMFT was 10.4 and mean DMFS 16.7. Differences in relation to sex were not significant. The distribution of subjects according to DMFS was uneven. The 20% with the highest DMFS accounted for about 45% of the total amounts of DS. A consistent pattern with higher mean DMFS in the low social groups was found. Attendance to Regular Youth Dental Service was higher the longer the subjects had been students and higher mean DMFS was found in nonregular attenders. The presence of a high caries risk group is discussed in relation to the dental care system received by the study population. PMID- 6929242 TI - Pilot results of DMF treatment time index. AB - The DMF Index and its components have been utilized by various researchers to measure aspects of the caries process ranging from prevalence of carious lesions to the amount of dental care needed. It is generally recognized that DMF Teeth (T) measures life-time caries experience and is not a good predictor of the amount of treatment time needed in population groups. The purpose of this study is to evaluate the ability of certain modifications of the DMFT components to predict the amount of treatment time needed. In a sample of 109 adult cases, normal and diseased conditions were coded along with the usual DMFT measures and the number of missing teeth needing replacement (NR). Corresponding treatment procedures related to caries (periodontal treatment was not coded) were recorded and then converted to treatment times using the Relative Productivity Unit (RPU). Stepwise multiple regression and discriminant analysis procedures were used. The number of D teeth was linearly related to treatment time, but the number of NR and M teeth were not. Regression procedures indicated that the square root values of D and NR were the best predictors of treatment time (RPU) and produced a multipler of 0.69. When patients were classified into categories of treatment time (low, medium, high), the DMF Treatment Time Index was able to correctly classify 70% of the cases into their appropriate treatment time category. PMID- 6929244 TI - Decayed, missing, and filled teeth among Jewish and Arab schoolchildren in Israel. AB - The purpose of this investigation was to gather information on caries prevalence in schoolchildren of Arab and Jewish populations, and compare caries prevalence according to sex, age and population examined. Altogther, 3672 children were included in the survey (1975 Jews, 1001 of whom were females; and 1697 Arabs, 840 of whom were females). During the examination only dental caries were checked. Caries were marked according to the DMF index. Compared to former years there is an increase in the prevalence of caries throughout the population. A slightly lower caries prevalence was found among Jewish children than among Arab children of the same age. However, when DMF is broken down into its component parts, Arab children were seen to have a greater number of teeth affected by caries and in need of treatment (D). Furthermore, treatment need has been met to a much greater degree among Jewish children than among Arab children. Arab children received almost no dental care. PMID- 6929245 TI - 44-year dental health survey of Helsinki schoolchildren. AB - The purpose of the present study was to establish whether the number of intact teeth in Helsinki schoolchildren aged 7-13 years was rationally correlated with the wartime reduction in sugar consumption and, later, with dental health education programs in Finland. The period covered is 44 years. The results show that dental health education is effective in caries prevention and that enforced programs can lead to an improvement similar to that seen during the war. PMID- 6929243 TI - Radiographic survey of periodontal disease in 264 adolescent schoolboys in Lagos, Nigeria. AB - Periapical radiographs were taken of central incisor and first molar teeth in 264 Nigerian boys (12-20 years) from a school in Lagos. From the radiographs, bone loss involving central incisors and first molars was measured. Bone loss was evident in 28.4% of subjects examined. The prevalence of bone loss rose through the age groups from 23.2% at 12-13 years to 34.6% at 18-20 years. Over all ages the prevalence of bone loss involving mandibular central incisors was 14.4%, mandibular first molars 9.8%, maxillary first molars 8.3% and maxillary central incisors 7.6%. Two subjects showed features characteristic of juvenile periodontitis (periodontosis). PMID- 6929246 TI - Critical care problems in the newborn: CVC in infants on assisted ventilation: prognostic indicator and ability to wean. PMID- 6929249 TI - Myelogenous leukemia: current practice. PMID- 6929248 TI - [Change in the topologic bond number of closed DNA loops during differentiation of mouse erythroleukemia cells]. PMID- 6929247 TI - The use of translocation-derived "marker-bivalents" for studying the origin of meiotic instability in female mice. AB - Female mice of two age groups, 3--4 and 11--14 months old, homozygous for the T(1;13)70H reciprocal mouse translocation were used for cytological observations of bivalents (in primary oocytes) and metaphase II chromosomes (in secondary oocytes). Special attention was given to the behavior of the long (131) and short (113) marker chromosomes. In primary oocytes, univalents were considered "true" or "opposite". The aged females showed an eight-folded increase in "true" univalent frequency for chromosomes 113 over the young ones. A nine-fold rise for nondisjunction with regard to this chromosome was observed. For the other chromosomes, these factors were 2 and 1.7, respectively. The absolute levels of nondisjunction remained low at old age (1.42% for chromosome 113, 1.22% for all other chromosomes). The long marker bivalent 131 was used for chiasma counts. No change in chiasma number with age was observed. It is argued that poorer physiological conditions within the maturing oocytes of older females are the major cause for both the increasing frequencies of "true" and "opposite" univalents and the increased incidence for nondisjunction. PMID- 6929250 TI - The kinetic mechanism of xanthine dehydrogenase and related enzymes. AB - Xanthine dehydrogenase and related enzymes contain multicomponent internal electron transfer chains. The topographical arrangement of this chain in such that the oxidation of substrate and the reduction of the electron acceptor occur at separate non-overlapping sites that communicate by intramolecular electron transfer. The steady-state kinetic behaviour of these enzymes is thus ideally suited to a two-site ping-pong mechanism, with random addition of substrates and products at the two sites. The formal mechanism of these enzymes is presented here as a mixture of rapid equilibrium random segments connected by a steady state segment, i.e. a rapid-equilibrium random (two-site) hybrid ping-pong mechanism. Such a mechanism is likely to be operative in a variety of oxidative enzymes containing multiple redox-active prosthetic groups. PMID- 6929251 TI - In vitro metabolism of progesterone in the mammary tumor and the normal mammary gland of GRS/A strain of mice and dependency of some steroid-metabolizing enzyme activities upon ovarian function. PMID- 6929252 TI - [Histological study of various forms of interdentin (tertiary dentin)]. PMID- 6929253 TI - [Incidence of orthodontic anomalies in a village of Rabakoz]. PMID- 6929254 TI - [Psychological methods for the prevention of adaptation disorders wearers of full dentures]. PMID- 6929255 TI - [Sequelae of injury to the front teeth in childhood]. PMID- 6929256 TI - [Giant submandibular salivary calculi]. PMID- 6929257 TI - [Hormone cytologic examination of the oral mucosa in women taking contraceptives pills]. PMID- 6929259 TI - [Thermal analysis and acid solubility of rat incisors treated with molybdenum]. PMID- 6929258 TI - [The effect of sugar solutions on water diffusion in enamel sections]. PMID- 6929262 TI - Radiographic illusions. PMID- 6929260 TI - [Tooth substitution by implantation]. PMID- 6929261 TI - [An instrument for measuring tooth mobility]. PMID- 6929263 TI - Jig for dental model photography. PMID- 6929264 TI - Simplified technic for thin-section radiography. PMID- 6929265 TI - Retained subgingival plastic foreign body. PMID- 6929267 TI - The lack of inhibition of nitrogenases of aerobic bacteria by the contact herbicide Dinoseb [proceedings]. PMID- 6929266 TI - The fate of liposome-entrapped actinomycin D in vivo and its therapeutic effect in a solid murine tumour [proceedings]. PMID- 6929269 TI - Osteosarcoma of the uterus: case report and review of the literature. PMID- 6929268 TI - The effects of a high fat diet on chronic streptozotocin-diabetic rats. AB - The effects of a high fat diet (30% (w/w) corn oil) on chronic streptozotocin diabetic rats were investigated at the whole body level and at the enzyme level. The diet caused significant decreases in the extent of polydipsia (66% decrease), polyphagia (49%), polyuria (67%) and glycosuria (70%). The activities of selected hepatic enzymes from the glycolytic, gluconeogenic, ureogenic and lipogenic clusters were determined. The fat diet caused significant decreases (range: 47 to 54%) in the activity of the ureogenic enzymes carbamyl phosphate synthetase, ornithine transcarbamylase and arginase; had no effect on the glycolytic enzymes glucokinase, hexokinase and pyruvate kinase; partially decreased the diabetes induced elevated activities of the gluconeogenic enzymes phosphoenolpyruvate carboxykinase (63% decrease), serine dehydratase (90%), alanine aminotransferase (31%) and aspartate aminotransferase (65%), and partially reversed the activity of one lipogenic enzyme, ATP citrate lyase. PMID- 6929270 TI - Accreditation problems: cost impact of standards is considered. PMID- 6929271 TI - Human phosphoglycolate phosphatase (PGP) E.C. 3.1.3.18: linkage analysis. AB - Linkage data on phosphoglycolate phosphatase (PGP) E.C. 3.1.3.18 and 26 other human genetic markers are presented. One hundred and one families from the southwestern area of Germany were tested. Close linkage between PGP and the following markers could be ruled out: ABO, acP, ADA, GPT, PGM1, GLO, HLA, and PGM3. There is some evidence for possible linkage with MNSs, Rh, Gm and EsD. Family segregation data confirm the hypothesis formerly established by Barker and Hopkinson: three common alleles PG1, PGP2 and PGP3 at an autosomal locus PGP. PMID- 6929272 TI - Elevation of serum polyamines in malignant lymphomas and acute myeloid leukemia. AB - In a study of 89 cases of hematological cancers including 55 cases of Hodgkin's disease, 21 of non-Hodgkin lymphoma and 13 of acute myeloid leukemia, the serum total polyamines were considerably elevated (1.2-5.7 nmol/ml) as compared to observations on control values for eight healthy individuals (0.62-0.87 nmol/ml). The assay procedure was based on enzymes oxidizing polyamines isolated from Russell's viper venom. Serial determination of polyamines in the sera of eight cases of Hodgkin's disease done before and after chemotherapy or radiotherapy showed positive correlation with clinical status of the disease. Analysis of individual polyamines in four patients with Hodgkin's disease indicated that putrescine may be a more sensitive marker of the diseased state. By the present method it was undetected in the control sera but rose significantly in the sera of patients with Hodgkin's disease. Overall data suggest that serum polyamines may be useful as indicators of onset of relapse in patients with Hodgkin's disease and could thus be helpful in early start of treatment. PMID- 6929274 TI - An automatic sigh feature for animal ventilators. AB - A device is described that provides a reliable automatic deep breath to an animal being ventilated with a typical laboratory ventilator. The deep breath is provided by closing a solenoid valve in the expiratory tubing causing the animal to inspire two, three, or four consecutive tidal volumes without expiration. The interval between deep breaths is selected to be every 1, 2, 4, 6, 8, or 10 min. Control of this interval is provided by simple integrated circuits. Total parts cost of this device is approximately $90. PMID- 6929273 TI - Potential pre-screening for therapeutic agents that induce differentiation in human myeloid leukemia cells. AB - A cultured line of human myeloid leukemic cells has been used, to test for the ability of compounds used in chemotherapy to induce partial or complete differentiation of these leukemic cells. The compounds differed in their ability to induce specific differentiation-associated properties. Effectiveness of induction of Fc and C3 rosettes was of the order actinomycin C greater than cytosine arabinoside greater than mitomycin-C greater than adriamycin greater than bromodeoxyuridine greater than hydroxyurea. Induction of rosettes by actinomycin-D required a 8212-fold lower concentration than induction by hydroxyurea. All these compounds, except bromodeoxyuridine, induced the synthesis and secretion of lysozyme with the same order of effectiveness as for rosettes, but only actinomycin-D and to a lesser extent bromodeoxyuridine induced the formation of mature granulocytes. Vincristine induced only a small increase in lysozyme. The results indicate that actinomycin-D was the most potent inducer of differentiation in these human myeloid leukemic cells. It is suggested that pre screening of individual patients for the most effective compounds that can induce differentiation of their myeloid leukemic cells in culture, may prove beneficial for treatment in a form of chemotherapy based on the induction of normal differentiation in leukemic cells. PMID- 6929275 TI - 1,25-Dihydroxyvitamin D3 receptor-like macromolecule in rat osteogenic sarcoma cell lines. AB - The hormonal metabolite of vitamin D3, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), exerts its biological effects by initially binding to a cytosolic receptor protein. Such a protein has been demonstrated in the target organs of vitamin D3 including bone. Although the role of 1,25(OH)2D3 on the skeleton has been extensively studied in normal bone, nothing is known about its effects, if any, in abnormal bone growth. Rat osteogenic sarcoma is a useful model for bone malignancy. Tumor cells retain differentiated functions including the ability to form bone and to respond to parathyroid hormone, prostaglandins, and to a smaller extent to calcitonin with increases in cyclic AMP levels. We have here evaluated osteogenic sarcoma cell lines for the presence of a receptor for 1,25(OH)2D3. We have utilized sucrose gradient sedimentation, saturation analysis, and DNA cellulose chromatography. Cytosol preparations from these cell lines contain a 3.3 S saturable macromolecule which binds 1,25(OH)2D3 with specificity and high affinity (Kd = 2 x 10(-10) M). The sterol-macromolecule complex binds to DNA cellulose and its elution profile from this affinity resin is similar to that of the 1,25(OH)2D3 receptor from normal rat bone. These tumor cells should serve as a useful model for studying the action of 1,25(OH)2D3 in bone and the role of this metabolite in the biology of bone malignancy. PMID- 6929276 TI - Colchicine resistant Friend cells: application to the study of actinomycin D induced erythroid differentiation. PMID- 6929277 TI - The cellular basis of self renewal in culture by human acute myeloblastic leukemia blast cell progenitors. AB - Blast cells from patients with Acute Myeloblastic Leukemia (AML) were separated according to cell size using velocity sedimentation under unit gravity. Fractions obtained in this way were plated in methyl cellulose with a growth stimulator present in media conditioned by leukocytes in the presence of phytohemagglutinin (PHA-LCM). Colonies of blast cells form under these conditions. Pooled cell suspensions from such colonies were plated in microwells; the plating efficiency of such suspensions is a measure of blast progenitor self-renewal occurring in the original blast colonies. Self-renewal assays on each fraction indicated that self renewal among blast progenitors is heterogeneously distributed with subpopulations differing in renewal capacities. The results are consistent with the view that blast cell subpopulations in AML undergo a series of transitions associated with decreasing self renewal capacity, analogous to that observed in normal hemopoiesis, where proliferative capacity decreases with increasing differentiation. PMID- 6929278 TI - Cross-infection in dentistry. PMID- 6929279 TI - Sterilization in general dental practice. PMID- 6929280 TI - The problem of cross-infection in dental surgery with particular reference to serum hepatitis. PMID- 6929281 TI - The management of sterilization in dental teaching hospitals. PMID- 6929282 TI - Characterization of glass--ionomer cements. 6. A study of erosion and water absorption in both neutral and acidic media. PMID- 6929284 TI - Cross-infection in dentistry with particular reference to oral surgery and periodontics. PMID- 6929283 TI - Graduates' opinions of their training in conservative dentistry. PMID- 6929285 TI - Talon cusp: a review and case report. PMID- 6929286 TI - Fluroide concentration in enamel treated with 50% phosphoric acid and NaF with subsequent decalcification in "acid-gel". AB - Fluoride concentration of enamel surfaces treated with 50% H3PO4, together with high NaF contents or etched with 50% H3PO4 followed by application with a water solution of high NaF content, was examined. In addition, the degree of decalcification and the fluoride content of subsequently incubated enamel samples in acid-gel at 37 degrees C were determined. Generally, incubation highly increased the fluoride contents of the etched and fluoridated (experimental), control (etched only), and untreated (vaseline) enamel samples. An increasing demineralization effect was observed in the samples of the following order: experimental, control, and baseline. It appears does not predispose to an increased caries challenge in vitro. PMID- 6929287 TI - The pathway of enamel rods at the base of cusps of human teeth. AB - Enamel increases in volume and surface area with distance from the dentin-enamel junction, particularly at cusps, while the number of rods remains constant. Our results indicate that the increase in volume may be due to the increased rod diameter near the tooth surface, a circumferential winding of rods in the parazone orientation of Hunter-Schreger bands, and the migration of rods from a mid-coronal origin at the dentin surface to a cuspal terminaton at the tooth surface. Increased surface area can be explained by the increased rod diameter and the oblique approach of rods to the tooth surface. PMID- 6929288 TI - Endotoxic activity in teeth with necrotic pulps. AB - From root canals of 13 teeth with necrotic pulps, samples were taken for analysis of endotoxin content by means of the Limulus by lysate technique. The results were related to the viable bacteria count of root canal samples, phenol/water extracted lipopolysaccharides (LPS) from different gram-negative anaerobic bacteria, and to different fractions of inflammation exudate. It was found that the endotoxic activity of the root canal samples was correlated with the presence and the number of gram-negative bacteria in the root canal. PMID- 6929289 TI - Physical properties of maxillofacial elastomers under conditions of accelerated aging. AB - The stability of the physical properties of various commercially available maxillofacial prosthetic materials was evaluated with the use of an accelerated aging chamber. The tensile strength, maximum percent elongation, shear strength, tear energy, and Shore A hardness were determined before and after accelerated aging. Results indicate that silicone 44210, a RTV rubber, is a promising elastomer for maxillofacial application. PMID- 6929290 TI - Glass-ionomer cement formulations. II. The synthesis of novel polycarobxylic acids. AB - The synthesis of many polycarboxylic acids is reported. An account is given of their stability in aqueous solution and the properties of cements formed by their reaction with ion-leachable glasses. A copolymer of acrylic and itaconic acids was found to combine several favorable characteristics. PMID- 6929291 TI - Effects of dental anxiety and phase of treatment on discomfort during dental simulation. PMID- 6929292 TI - Effect of fluoride rinses upon in vitro enamel remineralization. PMID- 6929293 TI - Systemic fluoride absorption following fluoride gel application. PMID- 6929294 TI - Dynamic mechanical analysis of the setting of amalgam. PMID- 6929295 TI - On the relaxation and recovery of orthodontic traction elements under interrupted loading. PMID- 6929297 TI - Comparison of the biological characteristics in two serotypes of Propionibacterium acnes. PMID- 6929296 TI - Cadmium gradient in human and bovine enamel. PMID- 6929298 TI - LC50 value for rats acutely exposed to methyl methacrylate monomer vapor. PMID- 6929299 TI - DNA synthesis of enamel organ epithelium in vitro is enhanced by co-cultivation with non-viable mesenchyme cells. AB - Developing enamel organ epithelium was cultured in the presence and absence of non-viable dental papilla mesenchyme cells. Epithelial cell proliferation was enhanced by 75% when cultivated on the mesenchyme cell substratum. The addition of epidermal growth factor (EGF) to enamel organ epithelium cultured on this substratum resulted in a synergistic enhancement of DNA synthesis. PMID- 6929300 TI - The secretion of protein and of some electrolytes in response to alpha- and beta- adrenergic agonists by rat parotid and submandibular salivary glands enlarged by chronic treatment with isoproterenol. AB - In comparison with control rats. chronic administration of isoproterenol (IPR) caused enlargement of the parotid and submandibular glands and the synthesis of apparently new proteins, probably by acinar cells. The parotid and submandibular saliva secreted in response to methoxamine or IPR differed markedly in protein and electrolyte content. In addition, with each stimulus, the salivas secreted by control and experimental glands differed in flow rate, protein concentration, and in the concentrations of certain of the electrolytes. PMID- 6929301 TI - Analytical electron microscopy of Bacterionema matruchotii calcification. AB - The morphology and elemental analyses of calcification occurring in Bacterionema matruchotii were studied by analytical electron microscopy. Early electron densities were found associated with metachromatic granules and cell membranes. Amorphous calcium phosphate appeared before apatite was detected. PMID- 6929302 TI - The psychophysiological theory of etiology for MPD syndrome. PMID- 6929303 TI - Departments of social dentistry--an update for the 1980s. AB - Two decades have passed since Blackerby's call to develop departments of social dentistry within dental schools. Recent events, having changed the climate for the delivery of health services, would seem to bear out the wisdom of such departments. A review of the development and present status of departments of social dentistry is provided with a discussion of evolving programs and need for a change in the relationship between departments of social dentistry and the general school teaching programs. PMID- 6929304 TI - The role of research in advanced dental education. AB - Research is an integral part of quality advanced programs. Clinical research should be done in all departments where advanced dental education occurs, because this is the best way to improve the scientific base and rationality of clinical treatment. At present, many departments with postdoctoral programs lack faculty and others resources for research productivity. Programs to produce clinical faculty with research training are needed. The development of clinical research centers would offer the potential of combined clinical training and research. Combining existing resources for maximum effectiveness will be important in producing stronger programs. PMID- 6929305 TI - Women dental students: preferences in support services. AB - Female dental students in 68 American and Canadian dental schools were surveyed to determine their attitudes and concerns about women in dental school, and their preferences in support services. Almost 80 percent of the women reported that their sex did not not hinder them in achieving peak academic success. They believe that qualifications, rather than sex, should be the primary consideration in admitting students and hiring faculty. The majority of respondents indicated that the most beneficial support service for women would be a seminar series specific to their concerns. They also believe that to have women dentists used as role models in lectures and textbooks would be both appropriate and supportive. PMID- 6929306 TI - Providing preventive dental care in the community using the team approach: a comparison of five training programs. AB - Five dental schools developed training programs for dental and dental auxiliary students in planning and delivering preventive dental services in a community setting. The schools (1) designed a curriculum that would train dental students to plan, organize, and manage the delivery of community preventive services using a team approach; (2) developed a related curriculum for dental auxiliary students; (3) implemented the program intramurally and extramurally in selected community settings; and (4) planned and conducted an evaluation of the program. Each school individualized the program to the interests of its students, the constraints of its curriculum, and the needs of community groups. A total of 228 dental and 576 dental auxiliary students were trained. A full range of community sites and target populations were provided with preventive dentistry services. PMID- 6929307 TI - Prediction of preclinical operative dentistry performance in two instructional methods. AB - This study evaluated the accuracy of manual and academic variables in predicting preclinical operative technique performance. In addition, it tested and compared two teaching methods and their effects on performance outcomes. Simple correlations and stepwise multiple regression analysis were used. Although correlations were low, they were significant for predicting performance using the Perceptual Motor Ability Test (PMAT) of the Dental Admission Test (DAT). The treatment of the two groups showed that students with low or average two dimension (2D) scores on the PMAT benefited from an alternate teaching method in the preclinical operative technique course. PMID- 6929308 TI - The preventive dental examination scorecard. PMID- 6929309 TI - A one-day pit and fissure sealant exercise. PMID- 6929310 TI - Ethical and legal considerations in dental caries research using human subjects: conference summary. PMID- 6929311 TI - American Association of Dental Schools curricular guidelines on fixed prosthodontics. PMID- 6929312 TI - American Association of Dental Schools curricular guidelines for removable prosthodontics. PMID- 6929313 TI - Sources of payments to faculty and staff. PMID- 6929315 TI - Self-concept and cognitive measures among male and female dental students. PMID- 6929314 TI - Patients' attitudes toward quality of assurance in dentistry. PMID- 6929316 TI - A clear message to the FTC. PMID- 6929318 TI - American dentistry and the public interest. PMID- 6929317 TI - The marks of an educated person. PMID- 6929319 TI - Survival and growth of a private dental school. PMID- 6929320 TI - L-asparaginase and toxic epidermal necrolysis. PMID- 6929321 TI - Vitamin C and antibiotics. PMID- 6929322 TI - Hand-foot-and mouth disease: a case report. PMID- 6929323 TI - Dental and skeletal maturation in patients with cystic fibrosis. PMID- 6929324 TI - Fibrinolysis in the rat after short-term aspirin therapy. AB - Fibrinolytic parameters were compared in blood taken from rats treated with aspirin (10 and 40 mg/kg) or saline solution. Plasma euglobulin fractions prepared from animals treated with the higher dose of aspirin caused increased zones of lysis on plasminogen-rich fibrin plates. Even greater lytic activity was detected in blood from all aspirin-treated rats when euglobulin fractions were augmented with sodium flufenamate and dextran sulfate. The inhibitor index was significantly reduced when calculated for rats treated with the larger dose of drug. Dilute blood clot lysis times for this group were consistently prolonged, most likely reflecting impaired platelet function. Platelet counts, hematocrits, and bleeding times did not differ from controls. Prothrombin times, activated partial thromboplastin times, and plasma clot times were all prolonged, reflecting the sensitivity of the vitamin K-dependent factors to aspirin. PMID- 6929325 TI - Sliding block resection and reconstruction in cases of carcinoma of the lower lip. AB - Surgical eradication of carcinoma of the lower lip is generally a curative maneuver. Concomitant reconstruction at this site is almost always necessary, however, and difficulties in these efforts often arise. Postoperative esthetic problems usually result when more than 30% of the lip has been removed; the most common problems are vertical scar retraction along the mucosal surface, unacceptable distortion of the commissure or overall asymmetry of the oral aperture, or both, and significantly disturbed lip motor function. During the past decade, the surgical procedure described has allowed excision of 40% of the lip and provided vertical support of the reconstructed lip and an ultimate facial appearance superior to that of other techniques. PMID- 6929327 TI - Clinical-pathological conference. Case 31, part 1. PMID- 6929328 TI - Effective use of dantrolene in a patient susceptible to malignant hyperthermia. PMID- 6929326 TI - Orthognathic and secondary cleft reconstruction of adolescent patients with cleft palate. AB - Midfacial reconstruction in adolescent patients with cleft palates is becoming increasingly practiced through a multidisciplinary approach that includes surgical, orthodontic, and prosthetic treatment. Four general types of cleft palate deformities in adolescents are discussed in terms of treatment. These include bilateral midfacial hypoplasia, unilateral midfacial hypoplasia, alveolar incompetence, and soft tissue incompetencies. The surgical treatment and associated considerations are presented. PMID- 6929331 TI - Simple bone cyst of the jaw: review of the literature and report of case. AB - Analysis of the data from 255 cases of simple bone cyst is presented. A rare case of multiple simple bone cysts in the mandible is also reported. Criteria for diagnosis, nomenclature, treatment, and prognosis of this entity are discussed. PMID- 6929329 TI - Desmoplastic fibroma of the mandible: report of case. AB - Desmoplastic fibroma of the bone is a rare tumor; only 48 cases of the disease have ever been reported. The tumor has most often been observed in the metaphysis of long bones. Nine cases of the lesion have been reported in the mandible. The lesion occurred in the left mandibular body of one of our patients. We treated the entity by surgically removing the tumor and concurrently reconstructing the jaw with a bone graft taken from the iliac crest. There has been no recurrence a year and eight months postoperatively. PMID- 6929330 TI - Solitary peripheral osteoma of the jaws: report of case and review of literature. AB - Solitary osteomas of the jaws are uncommon. Only 12 previous case reports provided acceptable clinical and histologic data. One new case is added. Most of the tumors occurred in the mandible; only three were intraoral. Histologically, eight were compact and five were cancellous osteomas. PMID- 6929332 TI - Possible squamous odontogenic tumor: report of case. AB - A patient with a possible squamous odontogenic tumor in the mandible is described. Treatment consisted of conservative surgical removal. PMID- 6929333 TI - Use of intradiploic cranial screws with a biphase appliance as a modified headframe. AB - An alternative method to using a standard headframe has been presented. A case has been presented demonstrating the application of the extracranial fixation using the biphase appliance. The basic acrylic headframe can be modified for traction wires as needed to produce maxillomandibular fixation. PMID- 6929334 TI - Exchange transfusion as a treatment for hyperleukocytosis, anemia, and metabolic abnormalities in a patient with leukemia. PMID- 6929335 TI - Antileukemic activity of 2-bis(2-methylthio)vinyl-1-methylquinolinium iodides. AB - Reaction of 1-methylquinolinium-2-dithioacetic acid zwitterions with excess methyl iodide in dimethylformamide gave the corresponding bis(2-methylthio)vinyl derivatives. These compounds were more soluble in both aqueous and organic media than the dithioacetic acid zwitterions but showed comparable antileukemic activity in mice. Reaction with morpholine converted a bis(2-methylthio)vinyl derivative almost quantitatively to the 2-mono(methylthio)-2-morpholino derivative. Leukemia cell culture studies of the 6-methyl derivative showed no effect on cell cycle processes. PMID- 6929336 TI - A new approach in construction of nasal septal obturators. AB - Nasal septal obturators are used to mechanically close nasal septal defects. The use of an impression of the nasal septal defect in the construction of nasal septal obturators is mandatory. A heat-cured, highly polished acrylic resin button constructed from an accurate impression is less likely to induce crusting and bleeding, or to be dislodged, than a Silastic button. PMID- 6929337 TI - Dust in dental laboratories. Part I: Types and levels in specific operations. AB - The type and levels of dust in breathing air close to the workpiece produced through cutting, grinding, or polishing of alloys in dental laboratories have been characterized. The dust levels were compared with threshold limit values (TWA or STEL). In laboratories with improper local ventilation systems, dust levels considerably exceeding such values were recorded. Levels in excess of 10 times the threshold limit values were observed for solid mercury and silver present in amalgam dust, for cobalt present in nonprecious alloys, and for gypsum. Silver exceeded the threshold limit value 1,750 times in one case. Moderate excess of threshold limit values, that is less than 10 times, were measured for copper, nickel, tin, and porcelain in cases of insufficient ventilation. With the efficient outlet systems available on the commercial market, the dust levels could be reduced to levels consistent with criteria of threshold limit values except when trimming amalgam dies. Such systems comprise tubes with diameters of 35 mm connected to pumps with suction capacities of about 30 l/sec. PMID- 6929338 TI - Myofascial pain-dysfunction: a manifestation of the short-face syndrome. PMID- 6929339 TI - Argon laser therapy of portwine stains. PMID- 6929340 TI - Lipoma of the uterus: a study and demonstration of the histogenesis of two cases. PMID- 6929341 TI - Laser therapy of glaucoma. PMID- 6929342 TI - Treatment of extensive infection from artificial "hair" implantation. PMID- 6929344 TI - Rupture of thoracic aneurysm into the right pleural space. PMID- 6929343 TI - Chronic granulocytic leukemia with normal leukocyte alkaline phosphatase score in a patient receiving lithium carbonate. PMID- 6929345 TI - Chaotic atrial mechanism. PMID- 6929346 TI - National Health Insurance. PMID- 6929347 TI - Second surgical opinion no solution for judgment. PMID- 6929348 TI - Zeal without understanding: federal intervention in medicine. PMID- 6929349 TI - Medical malpractice insurance. PMID- 6929350 TI - An environmental investigation of clusters of leukemia and Hodgkin's disease in Rutherford, New Jersey. PMID- 6929351 TI - Epidemiologic investigation of clusters of leukemia and Hodgkin's disease in Rutherford, New Jersey. PMID- 6929352 TI - Tracheal papillomatosis in an asthmatic presenting as upper airway obstruction. PMID- 6929353 TI - Physicians and the DRG model. PMID- 6929355 TI - [Studies on the shift of cefmetazole into the gastrointestinal tract (author's transl)]. AB - From the studies on the stability of cefmetazole and cefazolin in feces of animals and children, and the determination of the fecal concentration of cefmetazole in three pediatric patients, the following results were obtained. 1) When cefmetazole was kept at 37 degrees C for 24 approximately 48 hours in feces of rats, rabbits, dogs and children, it showed no decrease of the potency. On the other hand, cefazolin kept in the same condition as that of cefmetazole showed a remarkable decrease of the potency. 2) Fecal excretions of cefmetazole were 0, 0.22 and 0.65% of total doses, respectively, in two pediatric patients of scarlet fever and one pediatric patient of serous meningitis. PMID- 6929357 TI - [Acute toxicity of aclacinomycin A in mice, rats and dogs (author's transl)]. AB - New antitumor anthracycline antibiotic, aclacinomycin A was given to dd-mice and Wistar rats for acute toxicity study. The LD50 values were 29 approximately 39 mg/kg (i.v., i.p. and s.c.) and 62 approximately 69 mg/kg (p.o.) in mice, and 18 approximately 28 mg/kg (i.v., i.p. and s.c.) and 58 approximately 59 mg/kg (p.o.) in rats, respectively, which were calculated by mortality rate during a 14 day observation period. Depression of spontaneous activity, anorexia, diarrhea and slight alopecia were observed. Autopsy findings in animals killed by drug included atrophy of the thymus and spleen, and hyperemia and hemorrhage in the stomach and intestines. But no remarkable change was found in animals which survived through the observation period. Mongrel dogs were given the drug intravenously at 3, 5, 7.5, 10 and 15 mg/kg, respectively. All dogs (3/3) in the three higher dose groups and 1/3 dog in 5 mg/kg dose group died within day 0 approximately 5. Others survived more than 27 days. Depression of spontaneous activity and anorexia were found from 30 minutes to 2 hours after administration, followed by vomiting and diarrhea. Increase of GOT, GPT and LDH and decrease of WBC count were detected in dogs which died. Hyperemia and hemorrhage of the lungs, stomach and intestine were found among the groups given higher doses, whereas no significant changes were recognized among the two lower dose groups. PMID- 6929356 TI - [Antitumor spectrum of aclacinomycin A, MA 144 N 1 and MA 144 S 1 on the rat ascitic hepatoma (author's transl)]. AB - Antitumor activity of new anthracycline antibiotics aclacinomycin A, MA 144 N1 and MA 144 S 1 was studied on 11 cell lines of ascitic hepatoma in Donryu rats. These compounds showed similar antitumor spectrum against AH hepatoma; moderate effect on AH 13, 44, 66, 66F, 7974 and 60 C in the ip inoculation-ip treatment system. Aclacinomycin A showed a marked antitumor effect on AH 41 C in the iv-iv system, and AH 44 in the iv-ip and iv-po systems. The antitumor spectrum of aclacinomycin A seems to be different from that of adriamycin. PMID- 6929354 TI - Has the tide turned against socialized medicine? PMID- 6929358 TI - [Subacute toxicity of aclacinomycin A in rats (author's transl)]. AB - Wistar rats, both male and female, were treated with aclacinomycin A at 4 dosage levels (0.375, 0.75, 1.5 and 3.0 mg/kg/day) by daily intraperitoneal injection for 30 days. Several rats died in the two higher dose groups (1.5 mg/kg/day: male 2/8 and 3.0 mg/kg: male 8/8, female 8/8. Piloerection, anorexia, depression of spontaneous activity, diarrhea and slight incontinence were observed in rats in 3.0 mg/kg/day dose group. Body weight gain decreased after day 3 in rats receiving 1.5 and 3.0 mg/kg/day. A significant decrease in the total WBC count and a slight decrease in RBC count were observed in animals of 1.5 mg/kg/day dose group which were survived for 30 days. Autopsy findings demonstrated atrophy of the thymus and spleen, and hyperemia and hemorrhage in the intestine. The atrophy of the thymus and decreased hematopoiesis in the bone marrow were histologically noted in the two highest dose groups. No cardiotoxicity was observed. PMID- 6929359 TI - [Studies on the absorption, excretion and distribution of aclacinomycin A: absorption, excretion and distribution of 14C- or 3H-aclacinomycin A in mice, rats and rabbits (author's transl)]. AB - A new anthracycline antitumor antibiotic, aclacinomycin A, was labeled with 3H uniformly or with 14C simultaneously at the anthracycline nucleus and L rhodosamine. These labeled drugs were administered intravenously to normal dd mice, solid type Sarcoma 180 tumor-bearing ICR mice, normal or pregnant Wistar rats and normal rabbits, respectively. 14C-Aclacinomycin A given to rabbits (5 mg/kg) was rapidly cleared from the blood and transferred to tissues. But low level of radioactivity (equivalent to about 0.5 mcg/ml) was remained in the blood even 8 approximately 10 hours after administration. About 45% of the radioactivity were recovered from the urine and 20% from the feces by 72 hours after administration. Tissue levels of 3H-14C-aclacinomycin A given to normal and tumor-bearing mice were highest in the lungs and spleen. Higher distribution was observed also in the liver and kidneys 2 hours after administration. Bioassay revealed that the drug was present in the lungs and spleen in biologically active form and in the liver and kidneys in inactive form, respectively. In the tumor tissue the radioactivity was low but it persisted for 48 hours. Autoradiography with 14C-aclacinomycin A in rats demonstrated that radioactivity due to the drug distributed in the lungs, spleen, kidneys, thymus, intestine, lymph nodes, bone marrow, salivary gland, hypophysis and pineal body but it was rapidly cleared. About 0.2% of radioactivity given to a pregnant rat were transferred to a fetus when 14C-aclacinomycin A was administered intravenously on the 18 approximately 19th day of pregnancy. PMID- 6929360 TI - [Studies on the absorption, excretion and distribution of aclacinomycin A: absorption, excretion and distribution of aclacinomycin A in mice, rabbits and dogs by photometric assay (author's transl)]. AB - An anthracycline antitumor antibiotic, aclacinomycin A, was given to mice, rabbits or dogs intravenously to study the pharmacokinetics by photometric assay based on the absorption of anthracycline ring. The drug was rapidly eliminated from the blood in these animals. Drug levels were much higher in the blood cells than in the plasma. Tissue levels in dogs were 50 approximately 100 times higher than the blood levels, which showed the drug was rapidly transferred from the blood to tissues after administration. Higher levels were observed in the lungs, spleen and lymph nodes, where the drug was present as aclacinomycin A itself and the glycoside-type metabolites that were biologically active. The active form was also detected in the pancreas, heart, thymus, bone marrow and gastrointestinal tract. In the liver and kidneys, biologically inactive aglycone-type metabolites were observed. About 2 approximately 4% of the drug given to rabbits or dogs was recovered in the urine by 72 hours after administration, in which only 10% of the excreted drug was active form in rabbits but about 65% in dogs. The rest was inactive aglycone-type metabolites that were excreted almost in the conjugated form. Biliary excretion also contributed to the total clearance of the drug. Aclacinomycin A was absorbed even by oral administration in rabbits and dogs. Tissue distribution of the drug orally given to dogs was similar to that in intravenous administration, except that higher levels of active form were detected in the gastrointestinal tract and of inactive form in the liver. PMID- 6929361 TI - [General pharmacology of aclacinomycin A (author's transl)]. AB - The general pharmacology of aclacinomycin A, a new antitumor antibiotic, was studied in mice, rats, guinea-pigs, frogs, rabbits and dogs. The LD50 values of aclacinomycin A were 32.5 mg/kg (i.v.), 30.1 mg/kg (i.p.), 33.9 mg/kg (s.c.) and 69.7 mg/kg (p.o.), respectively in male mice, and 28.8 mg/kg (i.v.), 21.1 mg/kg (i.p.), 26.4 mg/kg (s.c.) and 58.6 mg/kg (p.o.), respectively in male rats. Aclacinomycin A had no effect on the central nervous system except potenciation of the pentobarbital sodium-induced anesthesia in mice. The contraction of isolated heart was stimulated in frogs while slightly inhibited in rabbits at higher concentration. Transient increases in the heart rate and the blood flow of peripheral vasculature were observed but the blood pressure was slightly lowered with respiratory excitation in anesthetized rabbits and dogs. The ECG (II-lead) demonstrated slight depression of R wave amplitude and slight sinus arrhythmia in dogs. Aclacinomycin A inhibited the contraction of isolated smooth muscle and antagonized some spasmogens. It inhibited the spontaneous movement of isolated rabbit ileum and rat uterus at higher concentration, and antagonized acetylcholine, histamine, serotonin and barium chloride in the contraction of isolated guinea-pig ileum. The antagonism was competitive to oxytocin and noncompetitive to acetylcholine in rat uterus, and noncompetitive to noradrenaline in rat deferent duct. The drug showed no apparent effect on the gastrointestinal propulsion in mice and on mucous membrane of the stomach in rats. However, it depressed gastric acid secretion in rats while slightly increased bile secretion in guinea-pigs. Urine volume and urinary excretion of electrolytes (Na+, K+) decreased in rats. Vascular permeability was slightly inhibited by the drug in rabbits and mice. No hemolytic effect was shown. Aclacinomycin A showed no antigenicity in anaphylactic reaction and SCHULTZ-DALE reaction in guinea-pigs. PMID- 6929362 TI - Conventional and two-dimensional real-time echocardiographic diagnosis of osteosarcoma. A case report. AB - A case of metastatic left ventricular osteosarcoma detected during life by conventional echocardiography was reported, and by 2-dimensional real-time echocardiography the spread and localization of osteosarcoma in the left ventricle were visualized directly. Our report is the first description of echocardiographic detection of osteosarcoma of the heart. PMID- 6929364 TI - [Splenectomy in chronic myeloid leukemia (author's transl)]. PMID- 6929363 TI - [Clinical significance of chromosomal abnormalities in acute non-lymphocytic leukemia (author's transl)]. PMID- 6929365 TI - [Blastic crisis of a chronic myelogenous leukemia with disseminated intravascular coagulation, with special reference to "AAAP" therapy (author's transl)]. PMID- 6929367 TI - Usefulness of statistical models to assess the benefit of breast cancer screening: a reply. PMID- 6929366 TI - [A case of chronic myelocytic leukemia associated with miliary tuberculosis (author's transl)]. PMID- 6929368 TI - Pharmacogenetics: an approach to understanding chemical and biologic aspects of cancer. PMID- 6929369 TI - Lack of association between cancer incidence and residence near petrochemical industry in the San Francisco Bay area. AB - Estimated age-adjusted incidence rates for cancer during 1971--77 among Kaiser Foundation Health Plan (KFHP) members living in a portion of the San Francisco Bay area (SFBA) characterized by a heavy concentration of petroleum and chemical industries were compared to estimated rates among KFHP members in the remainder of the SFBA. One hundred fifty-four comparisons were done for 41 selected cancer sites. The number of significant differences did not appear inconsistent with what might be expected by chance alone; furthermore, in most of these instances the so-called exposed area showed the lower rate. These findings provided some assurance that place of residence near petrochemical industries is not associated with increased cancer risk. PMID- 6929370 TI - Destruction of human solid tumors by alkyl lysophospholipids. AB - Alkyl lysophospholipids (ALP) are synthetic analogs of the naturally occurring 2 lysophosphatidylcholine. The effect of ALP on the proliferation of 22 different gynecologic malignant tumors in humans was studied in vitro. ALP caused progressive death of tumor cells over 24-96 hours. In addition, tumor specimens from the tested human tumors were xenotransplanted into NMRI nude mice. ALP induced a highly significant retardation of the in vivo growing human tumors. Neither oral nor iv administration of these compounds caused any recognizable side effects. PMID- 6929371 TI - Effect of tumor removal on the presence of lymphocytic cortisol metabolism enhancing factor in plasma of cancer patients. AB - Because lymphocytic cortisol metabolism-enhancing factor (LCMEF) is absent in the plasma of cancer patients (CP), this study was undertaken to determine the influence of tumor removal on this phenomenon. Known concentrations of human lymphocytes were incubated with cortisol in media containing 50% phosphate buffered saline (PBS) and 50% of one of the following: a) homologic normal plasma (HP),b) plasma from patients with noncancerous diseases (NCD) before surgery, c) plasma from patients with NCD after surgery, d) plasma from CP before tumor removal, e) plasma from CP after tumor removal, f) plasma from long-surviving CP (LSCP), and g) PBS. With the exception of plasma from the LSCP group, all the plasma had the capacity to enhance the lymphocytic cortisol metabolism (LCM) when compared with that of PBS. There was no significant difference between the metabolism obtained with HP and that obtained with plasma from patients with NCD either before or after surgery. The plasma from CP led to a significant reduction in activity, with no significant difference in conversion rates before and after tumor removal. The plasma from LSCP failed to enhance LCM, had a conversion rate similar to that of PBS and significantly lower than that of the plasma from CP, and appeared to contain no LCMEF. These findings, which showed that the lack of LCMEF in CP is not influenced by tumor removal, may indicate 1) that the lack of LCMEF preceded the appearance of cancer or 2) irreversibility of a possible anti LCMEF synthesis effect was induced by the tumor. PMID- 6929372 TI - Lack of correlation between carcinoembryonic antigen content of tumor extracts and leukocyte migration reactivity of tumor patients. AB - Tumor extracts varying in carcinoembryonic antigen (CEA) content (0.4--2,280 ng/mg protein) did not affect the reactivity of cancer patients' leukocytes in the leukocyte migration inhibition test (LMIT). In addition, variations in the plasma CEA levels of tumor-bearing leukocyte donors did not influence the frequency of significant LMIT reactivity. PMID- 6929374 TI - Inhibition by deoxycytidine, cytidine, and beta-cytosine arabinoside of the induction of alkaline phosphatase activity in HeLa cells. AB - The main objective of these experiments was the further examination of whether the induction of alkaline phosphatase activity in HeLa cells by 5-iodo-2' deoxyuridine (IdUrd) depends on the incorporation of IdUrd into DNA. Thymidine (dThd), deoxycytidine (dCyd), cytidine, and beta-cytosine arabinoside (Ara-C) inhibited a dose-dependent manner the induction of alkaline phosphatase activity by IdUrd in HeLa cells, and 5-iodo-2'-deoxycytidine induced activity in a dose dependent manner at concentrations similar to those of IdUrd. Three of these compounds, dThd, dCyd, and Ara-C, were studied with regard to degree of inhibition of induction and IdUrd incorporation into DNA. Although the various doses of these three compounds decreased the incorporation of IdUrd into DNA, there was no apparent linear correlation between the extent of inhibition of IdUrd incorporation and the degree of inhibition of the induction of alkaline phosphatase activity. dCyd also inhibited a dose-dependent manner the induction of alkaline phosphatase by hydrocortisone, sodium butyrate, and choline chloridee. These results, although not unequivocal, support the idea that IdUrd induction of alkaline phosphatase activity in HeLa cells does not require IdUrd incorporation into DNA. The dCyd altered the thermostability for alkaline phosphatase activity from control or IdUrd-treated cells, and for controls cells the change in thermostability occurred without a change in the enzyme specific activity. PMID- 6929375 TI - Biologic and immunologic studies on a murine model of regional lymph node metastasis. AB - Some biologic, hematologic, and immunologic aspects of the growth and metastasis of the MC-2 fibrosarcoma indicated its suitability as a model for the study of lymphogenous metastasis. The tumor was maintained in syngeneic female BALB/c mice by the serial sc passage of 10(5) viable tumor cells. It metastasized macroscopically in all mice to regional lymph nodes (RLN) and to the lungs. Both forward and retrograde node-to-node metastases were found. Tumor growth and metastasis were associated with splenomegaly, thymus atrophy, cachexia, neutrophilia, lymphopenia, and anemia. Tumor excision at various times after inoculation showed that all mice whose tumors were excised when there was histologic evidence of metastasis in all RLN (day 13; mean of tumor wt, 122 mg) died subsequently from metastases, whereas no animals died whose tumors were excised on or before day 8 (mean of tumor wt, 15 mg). The onset of metastasis was seen in some RLN on day 8. All survivors were immune to challenge with 10(5) viable tumor cells, which demonstrated the immunogenicity of the tumor. Concomitant tumor immunity could be demonstrated prior to the onset of metastasis (days 6 and 7) but not early (days 0--2) or late (days 15, 19, and 20) in primary site tumor growth. The early immune response to the tumor demonstrable as concomitant tumor immunity appeared to be abrogated by the progressive growth and metastasis of the neoplasm. Tumor cells passaged in adult thymectomized, X irradiated, syngeneic recipients produced larger RLN metastases and smaller primary tumors than those passaged in control mice. PMID- 6929373 TI - Effects of aflatoxin B1 on pregnant inbred Sprague-Dawley rats and their F1 generation. A contribution to transplacental carcinogenesis. PMID- 6929376 TI - Development of a 9L rat brain tumor cell multicellular spheroid system and its response to 1,3-bis(2-chloroethyl)-1-nitrosourea and radiation. PMID- 6929377 TI - Characteristics of transplantable tumors induced in the rat by N-2 fluorenylacetamide: elevations in tissue and serum sialic acid. AB - The correlation between levels of sialic acid and sialic acid-containing glycolipids (gangliosides) in tumors and serum with the growth characteristics of the tumors was investigated in transplantable hepatomas and squamous cell carcinomas initiated with the carcinogen N-2-fluorenylacetamide and propagated in vivo and in tissue culture. Tumor lines varied in histologic classification, growth rate, and ability to form pulmonary metastases. There was neither a correlation between growth rate and histologic classification nor between either of these two parameters and the ability to metastasize. Total and ganglioside sialic acid levels were elevated in carcinogen-treated liver and in transplantable hepatomas when contrasted with normal liver. Levels of sialic acid showed a weak correlation with the growth rate of hepatomas. Gangliosides from nonmetastatic hepatoma lines exhibited less N-acetylneuraminic acid--galactose- glucose-N--acylsphingosine (GM3) and an increased ratio of total monosialogangliosides to disialogangliosides than did metastatic lines. Ganglioside patterns of metastatic hepatoma lines more closely resembled the ganglioside patterns of normal liver than did those of the nonmetastatic lines. Concomitant elevations of total and ganglioside sialic acid levels were observed in sera of animals bearing subcutaneous implants. Serum levels of total sialic acid did correlate with total sialic acid levels found in the tumor tissues. The levels of serum sialic acid were not correlated directly with levels of serum sialyltransferase activity. Elevations of both tissue and serum ganglioside sialic acid were consistent features of liver tumorigenesis in the rat after N-2 fluorenylacetamide administration. They appeared, furthermore, to be early events not directly related to tumor cell differentiation or metastasis. PMID- 6929378 TI - Tumor metastases and cell-mediated immunity in a model system in DBA/2 mice. VII. Interaction of metastasizing and nonmetastasizing tumors with normal tissue in vitro. AB - Three mouse tumors known to metastasize in vivo and 3 nonmetastasizing mouse tumors that grow only locally in vivo were examined for their ability to adhere to and invade normal syngeneic lung organ cultures in vitro. All 3 metastasizing tumors adhered to and invaded the normal lung cultures. In contrast, tumors that grow only locally in vivo neither adhered to nor invaded the normal lung tissue. The described system is ideally suited to correlate the in vivo invasiveness of a given tumor with its potential to metastasize in vivo and to study in vitro how to influence the interaction of metastasizing tumor cells with normal tissue. PMID- 6929379 TI - Study of the carcinogenicity of large doses of dimethylnitramine, N-nitroso-L proline, and sodium nitrite administered in drinking water to rats. AB - Large doses of dimethylnitramine (DMNM), N-nitroso-L-proline (NPRO), and sodium nitrite were administered in the drinking water to MRC Wistar rats for at least 1 year, and the rats were maintained for life. DMNM (total dose, 20 g/kg) produced liver tumors in 25 (69%) of the 36 rats and nasal cavity tumors in 9 (25%) of the rats. NPRO (total dose, 36 g/kg) induced no tumors in 37 treated rats. In the group receiving NaNO2 (3.0 g/liter drinking water; total dose, 63 g/kg), 8 (18%) of 45 rats had forestomach squamous papillomas. The tumor incidence in the NaNO2 treated group was significantly greater than that of 2% in a control group started 11 months earlier, which suggested that the NaNO2 was tumorigenic in this experiment. PMID- 6929380 TI - Changes in DNA content during in vitro transformation of mouse salivary gland epithelium. AB - DNA content was measured in single cells in situ during the in vitro development of neoplastic transformation in epithelial cells from mouse salivary glands. The earliest change in DNA content was found in stage III of the transformation process (a preneoplastic stage). In foci of these cells, the percentage of tetraploid (4C) cells was 30--60% compared with the starting tissue and early primary cultures, which were diploid. The stage III foci eventually gave rise to subtetraploid tumorigenic cell lines. The studies suggested that during in vitro development of neoplastic transformation in salivary gland epithelium, tetraploids were generated that then underwent a period of chromosome instability and loss. Evidence was also presented that a similar mechanism may be operating in transformation of salivary gland epithelium in vivo. A possible mechanism for transformation on the basis of chromosome imbalance was discussed. PMID- 6929381 TI - Depressed growth of Morris hepatomas in altitude- and heat-stressed but not in cold-stressed buffalo rats. AB - Female inbred BUF rats bearing Morris hepatomas 5123C, 5123D, 7795, and 7800 bilaterally in the femoral musculature were exposed for 3 weeks to ether 4,500-m simulated altitude or sea level or to an ambient temperature of either 7, 23, or 33 degrees C. Rats were given inoculations 12 days before these exposures. Tumor size, body weight, food consumption, and body temperatures were measured weekly in these treated rats and in normal rats. At time of killing, tumor mass, DNA synthesis (by [3H]thymidine incorporation), and respiration (by conversion of [1,4-14C]succinic acid to 14CO2) were measured in each of the 4 hepatoma lines, in the livers of normal and host rats, and in regenerated livers 10 days post 70% hepatectomy. Growths of all 4 tumors and regenerated livers were significantly impaired in rats stressed by exposure to altitude and heat but not to cold. Neither DNA synthesis nor respiration was altered in the hepatomas and livers by any environmental stress. The environmentally stressed rats gained weight at a slower rate and consumed less food than did their controls, but no differences were found in these variables for tumor-bearing and non-tumor-bearing rats. However, whereas the ratio of body weight gain to food consumed was reduced under the three stressful environments, that of tumor weight gain to food consumed was not altered by any environment. Host survivorship was not influenced by any of these effects. PMID- 6929383 TI - Inhibitory effect of disulfiram on rat mammary tumor induction by N-2 fluorenylacetamide and on its metabolic conversion to N-hydroxy-N-2 fluorenylacetamide. AB - The effect of an antioxidant, disulfiram (DSF), on the carcinogenicities of N-2 fluorenylacetamide (2-FAA) and N-hydroxy-N-2-fluorenylacetamide (N-OH-2-FAA) was examined. DSF given in a diet at a concentration of 0.9% for 1 week before and throughout the carcinogen treatment (0.1 mmol/kg 3 times a week for 4 weeks) reduced the incidence of mammary tumors induced with 2-FAA by 50% and extended the mean latency period of malignant tumors from 5 to 10 months. By contrast, DSF had no effect on mammary carcinogenesis by N-OH-2-FAA. Consistent with these results was the demonstration of the inhibitory effect of DSF on the first step of metabolic activation of 2-FAA, i.e., N-hydroxylation. N-hydroxylation of 2-FAA was significantly inhibited in hepatic microsomes of untreated and 2-FAA-treated male and female rats by DSF given orally. A similar inhibition was shown in vitro after preincubation of hepatic microsomes with DSF. Measurements of cytochrome P450 after pretreatment of rats or microsomes with the inhibition showed no appreciable changes in the hemoprotein content. It was concluded, therefore, that the inhibitory effect of DSF on N-hydroxylation of 2-FAA is accomplished through mechanism(s) other than depression of the cytochrome P450 level. Because both 2 FAA and DSF bind to cytochrome P450 producing a type I spectrum, DSF may interfere with the binding of 2-FAA and thus alter its metabolism. PMID- 6929382 TI - Mammary carcinogenic effect of low-dose fission radiation in Wistar/Furth rats and its dependency on prolactin. AB - The mammary carcinogenic effect in rats of low-dose fission radiation and its dependency on prolactin were studied. A total of 141 female W/Fu rats were exposed to 4.8, 8.9, or 19.5 rads of fission radiation that had both fision neutrons of 2.0 million electron volts (MeV) and gamma ray components similar to those produced by the Hiroshima bomb. Only 1 of 48 rats (2.0%) developed mammary tumor (MT) after irradiation alone, whereas 20 of 48 rats (41.6%) developed MT's if prolactin was supplied shortly after irradiation by means of grafting of the prolactin-secreting pituitary tumor. Furthermore, MT's occurred in 11 of 45 rats (24.4%) treated with prolactin as late as 12 months after irradiation, which suggested the long-term survival of radiation-induced dormant MT cells. A correlation was found between the development of MT and the elevation of serum prolactin level; most MT's appeared shortly after the grafted mammotropic pituitary tumor became palpable. The growth of MT's appeared to be promoted by prolactin in collaboration with ovarian hormones; the growth of adenocarcinomas was dependent on prolactin and ovarian hormones, whereas the growth of fibroadenomas appeared to be less hormone-dependent. Much higher biologic effectiveness, especially in the low-dose range, was found with 2.0-MeV fission neutrons compared with 14.1-MeV fast neutrons or 180-kilovolt peak X-rays in rat mammary carcinogenesis. PMID- 6929385 TI - Quantitative in vitro transformation of Syrian golden hamster embryo cells with the use of frozen stored cells. AB - Quantitative transformation by carcinogens of Syrian golden hamster embryo cells from primary, secondary, or tertiary cultures could be obtained from cell pools frozen prior to any culturing with the same efficiency as with fresh cells. Cells retained the ability to activate a wide range of chemical carcinogens when the noncultured hamster cells were cooled at a controlled rate and when the established procedures for culturing cells were followed. The number of experiments that could be done with cells derived from frozen hamster pools could be increased by substitution of a hamster cell line for the feeder layer. The response to chemical carcinogens of different classes including carcinogenic hydrocarbons, aromatic amine derivatives, metal complexes, aflatoxin B1, N-methyl N'-nitro-N-nitrosoguanidine, and UV irradiation was similar to that reported with fresh cells. Transformation rate increased with increasing carcinogen concentration. The factors important for the breeding of healthy animals and for selection of those appropriate for obtaining reproducible transformation experiments were enumerated. PMID- 6929386 TI - Carcinogenic effects of combined treatment of inbred mice with 3 methylcholanthrene and 1,2-dimethylhydrazine. AB - Inbred mice of strains C57BL/6J (B6) (Ahb/-Ahb) and DBA/2J (D2) (Ahd/Ahd) were administered 3-methylcholanthrene (MCA) alone, 1,2-dimethylhydrazine (DMH) alone, and MCA and DMH together. Colorectal tumors were observed in 32% of the DMH treated B6 mice, but no such tumors occurred in similarly treated D2 mice. Of the MCA-treated D2 mice, 46% were susceptible to leukemia, whereas in similarly treated B6 mice, 19% developed only lung tumors. The combined application of MCA and DMH resulted in an increased incidence of colorectal (52%) and lung (44%) tumors in B6 mice and, to some extent, of leukemia (63%) in D2 mice. The role of genetic background on the carcinogenic effects of combined application of MCA and DMH in inbred mice is discussed. PMID- 6929384 TI - Sensitization to hyperthermia below 43 degrees C induced in Chinese hamster ovary cells by step-down heating. AB - Step-down heating (SDH) of Chinese hamster ovary cells consisted of an acute heat treatment at an elevated temperature followed immediately by chronic exposure to a lower hyperthermic temperature [step-down temperature (SDT)]. The survival curve at the SDT showed a reduced D0 (dose required to reduce the cell population to 37% on exponential part of the curve) relative to that of control cells only for SDT of 43 degrees C or less. The ratio r of D0's, D0 (control)/D0 (SDH), varied inversely with the SDT (e.g., r = 13 for SDT = 40 degrees C, whereas r = 1.3 for SDT = 43 degrees C). The degree of sensitization, as measured by r, was independent of the conditioning temperature (CT) and the conditioning time, provided that the CT was above 43 degrees C and the conditioning treatment reduced cell survival to 60% or less. The ratio r could be defined mathematically as a function of the activation energies for heat-induced cell killing above and below 43 degrees C, the SDT, and the CT. Biphasic heat survival curves, which appeared with heating at constant temperature below 43 degrees C, also appeared under SDH conditions, which suggested that thermotolerance, as represented by the resistant phase of the biphasic survival curve, was not affected by SDH. Fractionation experiments to measure the loss of interaction of heat damage remaining from the conditioning treatment with the low-temperature heat damage showed that 63% of the 45 degrees C sublethal damage was removed by 67 minutes at a constant exponential rate. PMID- 6929387 TI - Stable heat-resistant variants in populations of Chinese hamster cells. AB - Sublines with increased survival at elevated temperatures were obtained by repeated exposure of V79 Chinese hamster lung cells to 44.5 degrees C followed by regrowth of survivors to mass populations at 37 degrees C. After three cycles, the time at 44.5 degrees C required to reduce cell survival to 37% (D0 value) increased from 4.6 to 26.3 minutes. Clonal isolates retained their resistance to thermal stress for at least 3 months in culture at 37 degrees C and showed distinctive differences from precursor cells in growth rate and colonial morphology. These differences disappeared in hybrids constructed between resistant and sensitive cells. In assays of 44.5 degrees C, hybrid survival was only slightly increased over levels obtained with sensitive cells. Heat resistance and associated marker characteristics thus appear to be recessive or weakly codominant. Cytohybrids were also constructed by fusing cytoplasts from sensitive cells to nucleated heat-resistant cells. No cytoplasmic transfer of marker characteristics was detected in these combinations, which suggests that controls for heat resistance are nuclear in origin. PMID- 6929388 TI - Hepatocarcinogenicity of sterigmatocystin and versicolorin A to rainbow trout (Salmo gairdneri) embryos. AB - Versicolorin A (VA) and sterigmatocystin (ST) are biosynthetic precursors of aflatoxin B1 (AFB1). The carcinogenicity of these compounds relative to AFB1 was determined with the use of rainbow trout (Salmo gairdneri) embryo exposure. Exposure of 14-day rainbow trout embryos to a 0.5-ppm aqueous suspension of ST for 1 hour produced a 13% incidence of hepatocellular carcinomas among survivors 1 year later. Similar exposure of trout eggs to a 0.5-ppm solution of AFB1 produced a 53% incidence among survivors. Subsequent exposure of 21-day rainbow trout embryos to 5- and 25-ppm solutions of VA resulted in hepatocellular carcinoma incidences among survivors of 42 and 68%, respectively, at 12 months. A 0.5-ppm AFB1 positive control group had a 68% incidence among survivors of hepatocellular carcinomas at 1 year. These results established the carcinogenicity of VA for the first time and confirmed previous reports of ST carcinogenicity. Both compounds were of sufficient potencies to warrant caution as possible human health hazards. PMID- 6929390 TI - Adenocarcinoma of the kidney. III. Histogenesis of renal adenocarcinomas induced in rats by N-(4'-fluoro-4-biphenylyl)acetamide. AB - The histogenesis of renal adenocarcinoma induced in F344 rats by the carcinogen N (4'-fluoro-4-biphenylyl)acetamide (FBPA) was described in order to clarify the site of origin of this neoplasm within the nephron. FBPA was added to the diet up to 48 weeks, and the animals were killed at intervals from 4 to 52 weeks after initiation of the carcinogenic diet. As seen by light microscopy, tumors appeared to arise from the pars recta of the proximal tubule in a series of stages progressing from focal hyperplasia with dysplasia to development of small, then large, neoplastic nodules composed of moderately basophilic, closely packed tumor cells arranged in individual aggregates or lobules surrounded by basement membrane-like material. Karyomegaly, cystic lesions, foam cell lesions, interstitial fibrosis, and casts also accompanied tumorigenesis in this animal model. PMID- 6929392 TI - Mutagenic activation of N-2-fluorenylacetamide and N-hydroxy-N-2 fluorenylacetamide in subcellular fractions from X/Gf mice. AB - The Salmonella mutagenesis test system was used to evaluate the in vitro mutagenic potency of N-2-fluorenylacetamide (2-FAA) and N-hydroxy-N-2 fluorenylacetamide (N-OH-2-FAA) mediated by liver and kidney subcellular fractions from X/Gf mice, a strain resistant to 2-FAA carcinogenesis. Pretreatment of the mice with the microsomal inducers 3-methylcholanthrene (MCA) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) increased the number of revertants from both liver and kidney fractions. Mutagenicity of N-OH-2-FAA mediated by liver or kidney microsomes was partially inhibited at 0.001--0.1 microM Paraxon (diethyl-p-nitrophenyl phosphate), an inhibitor of deacetylase enzyme, and the inhibition was complete (98%) in microsomes from control mice (100 microM Paraoxon). Conversely, the liver and kidney microsomal fractions from MCA- and TCDD-treated X/Gf mice were less sensitive to Paraoxon. The inhibition of kidney or liver cytosol-mediated N-OH-2-FAA mutagenicity by Paraoxon was less than that observed with the microsomal fraction (50% inhibition at 1 x 10(-7) and 1 x 10( 5) M Paraoxon, respectively). The mutagenicity of 2-FAA and N-OH-2-FAA mediated by liver or kidney subcellular fractions from X/Gf mice and its response to inducers and inhibitors of mutagenic activation processes appear similar to those observed in species both resistant (cotton rat) and sensitive (Sprague-Dawley rat, NIH Swiss mice) to 2-FAA carcinogenesis. PMID- 6929391 TI - Adenocarcinoma of the kidney. IV. Electron microscopic study of the development of renal adenocarcinomas induced in rats by N-(4'-fluoro-4-biphenylyl)acetamide. AB - Ultrastructural features of various stages in the histogenesis of renal adenocarcinoma induced in F344 rats by the carcinogen N-(4'-fluoro-4 biphenylyl)acetamide (FBPA) are described. FBPA was added to the diet up to 48 weeks; animals were killed at intervals from 4 to 52 weeks. Characterized were foci of cellular alterations followed by foci of proliferation with dysplasia leading to solid and cystic lesions, carcinoma in situ, and finally, carcinoma. Other lesions included foam cell nodules. Alterations also were noted in distal tubules. By electron microscopy, subtle changes in some proximal tubule cells of the pars recta were noted by 4 weeks (foci of cellular alteration). By 12 weeks there was evidence of dedifferentiation and reduction of cell polarity, thickening of basal lamina, alterations in endoplasmic reticulum and mitochondria, and increases in residual bodies. Nuclei of these cells possessed large nucleoli. From 24 to 36 weeks foci of proliferation were seen and consisted of tumor cells arranged in solid and cystic configurations. In solid lesions (less than 3 mm), in addition to the above alterations, cells showed a microvillus brush border in unusual locations, small and irregular mitochondria, multiple Golgi complexes and basal lamina, and loss of cell polarity. From 36 to 52 weeks carcinoma in situ consisted of cells similar to tumor cells described above. In addition, intracellular canaliculi were present. Areas of tumor cell degeneration and necrosis also were seen. Cells of larger carcinomas (greater than 3 mm), also observed at this interval, were identical to those of carcinoma in situ. Calcification of necrotic debris was noted. PMID- 6929389 TI - Carcinogenicity of deuterium-labeled N-nitroso-N-methylcyclohexylamine in rats. AB - F344 rats were treated with both unlabeled N-nitroso-N-methylcyclohexylamine (NMC) and deuterium-labeled NMC (NMC-d3) in the methyl group. Both compounds were administered in the drinking water at concentrations of 50 and 12.5 mg/liter. The NMC-d3 was not less carcinogenic than the unlabeled NMC, which suggested that oxidation of the methyl group is not a rate-limiting step in the induction of esophageal tumors. PMID- 6929394 TI - The annual meeting: "unity and concert of action". PMID- 6929393 TI - Determination of glucocorticoid receptors in human leukemias. AB - Determination of steroid receptors has been used to predict steroid sensitivity in various neoplasias. In an attempt to investigate its applicability in human leukemias we have studied glucocorticoid receptors in the leukemic cells from 23 patients with various hematologic neoplasias and in the lymphocytes from 18 normal donors. Specific glucocorticoid binding in intact cells was determined by a whole cell competitive binding assay. Normal lymphocytes have about 4,611 specific binding sites per cell. The blasts from 9 patients with acute myelogenous leukemias (AML) have strongly varying high levels of specific binding sites, ranging from 4,817 to 15,416 per cell. Of the 13 patients with chronic lymphocytic leukemia (CLL), 5 have received glucocorticoid treatment for years and were clinically resistant to glucocorticoid. Their lymphocytes have lower specific binding sites (range: 2,047 to 3,999) than the other CLL cases which were newly diagnosed (range: 3,734 to 11,020). Our results suggest that determination of glucocorticoid receptors might be of value in predicting clinical responsiveness in leukemias. PMID- 6929395 TI - A survey of hemoglobin variations in South Carolina. PMID- 6929396 TI - Gastrointestinal disorders associated with disease primarily of other systems. PMID- 6929397 TI - The role of the University of South Carolina School of Medicine. PMID- 6929399 TI - [Clinical significance of the gingival exudate]. PMID- 6929398 TI - Pathogenesis of the anemia of Shay Chloroleukemia. AB - The pathogenesis of anemia of the Shay chloroleukemia (SCL) was studied in rats following SC, IP and IV inoculation of chloroma cells. Little difference in survival was noted regardless of the route of inoculation. A decrease in hamatocrit occurred in all SCL rats during approximately the final 48 hours of the disease; however, the anemia was more severe in SC- and IP-inoculated terminal rats than in SCL rats inoculated IV. A reduction in the numbers of normal cellular elements was noted in the femoral bone marrow of most terminal rats studied which was found to correlate inversely with the leukemic blast cell content of the marrow. No correlation was observed between the erythroblast content of the marrow and the degree of anemia. The number of erythroblasts varied from greatly reduced to normal in terminal SCL rats despite severe anemia. Moreover, the greatest reduction of both normal marrow cellularity and erythroblast numbers was observed in IV inoculated rats which consistently displayed the highest hematocrits in the terminal stage of the disease. Thus, the terminal anemia appears to be due primarily to excessive red cell loss. The decrease in erythroblasts, when observed, was most striking in the orthochromatophilic and polychromatophilic stages of erythroid maturation. PMID- 6929400 TI - A glycogen storage disease (gsd/gsd) rat: studies on lipid metabolism, lipogenesis, plasma metabolites, and bile acid secretion. PMID- 6929402 TI - Properties of the nonlethal recombinational repair deficient mutants of bacteriophage T4. III. DNA replicative intermediates and T4w. AB - The rate at which 3H thymidine is incorporated into DNA is increased in T4w infected cells compared to wild-type when measured late in infection under conditions of low thymidine concentration. This increased DNA synthesis is sensitive to hydroxyurea but not to mitomycin C, and can be prevented by the addition of chloramphenicol early in infection. Also, DNA replicative intermediates isolated from T4w-infected cells late in infection sediment significantly faster than those isolated from wild-type-infected cells. In contrast, DNA replicative intermediates isolated from T4x- or T4y-infected cells sediment more slowly than those produced by wild-type T4. Cells coinfected with wild-type T4+ and T4x, y or w; or T4w and T4x or y, produce wild-type DNA replicative intermediates. Cells coinfected with T4x and T4y produce more slowly sedimenting DNA replicative intermedites. Cells coinfected with T4w and wild-type T4 show wild-type rates of DNA synthesis while cells coinfected with T4w and T4x or T4y show increased rates of DNA synthesis over that observed with wild-type alone. PMID- 6929403 TI - A new variant of late-onset myophosphorylase deficiency. AB - McArdle disease classically presents in childhood or adolescence. Rarely does it become symptomatic for the first time in late adulthood, with the onset of progressive muscle wasting and weakness. Our patient is unusual in that despite a life of physical vigor, she developed immobilizing cramps, stiffness, and muscle swelling abruptly at age 60. She had no previous symptoms of muscle disease. The diagnosis was indicated by the ischemic forearm test, which produced muscle contracture and no rise in venous lactate levels, and confirmed by histochemical, electrophoretic, and biochemical studies that showed complete absence of myophosphorylase. This case defines a new variant of the late-onset type and raises important questions about compensatory mechanisms, inheritance patterns, and etiological factors in myophosphorylase deficiency. PMID- 6929401 TI - Genetic analysis of bacteriophage P4 using P4-plasmid ColE1 hybrids. AB - A set of plasmids that contain fragments of the bacteriophage P4 genome has been constructed by deleting portions of a P4-ColE1 hybrid. A P4 genetic map has been established and related to the physical map by examining the ability of these plasmids to rescue various P4 mutations. The P4 virl mutation and P4 genes involved in DNA replication (alpha), activation of P2 helper genes (delta and epsilon), polarity suppression (psu) and head size determination (sid) have been mapped, as has the region responsible for synthesis of a nonessential P4 protein. One of the deleted plasmids contains only 5900 base pairs (52%) of P4 but will form plaques if additional DNA is added to increase its total size to near that of P4. This plasmid is also unique in that it will not form stable associations with P2 lysogens of E. coli which are recA+. P4 alpha mutants can be suppressed as a result of replication under control of the ColE1 part of the hybrid. PMID- 6929405 TI - Gene machining sweeter gum. PMID- 6929404 TI - Y-chromosome structural rearrangement in Philadelphia chromosome-negative chronic myelogenous leukemia. PMID- 6929406 TI - Expression of human alpha-globin genes in hybrid mouse erythroleukaemia cells depends on differentiated state of human donor cell. AB - We have developed a system which can be used to study the mechanisms that may govern the expression of human alpha-globin genes in human erythroid and non erythroid haematopoietic cells. Human chromosome 16, which has been shown to bear the human alpha-globin genes, is introduced by cell fusion into mouse erythroleukemia (MEL) cells to generate continuously proliferating cell lines that retain permanently the human alpha-globin genes. We have shown that hybrid diploid MEL cells with human alpha-globin genes from erythroid donor cells express these genes fully through globin chain synthesis, while hybrid diploid MEL cells containing human alpha-globin genes from non-erythroid human haematopoietic donor cells contain very low levels of human alpha-globin mRNA and no detectable human alpha-globin chains. The levels of human alpha-globin mRNA in these hybrid cells were found to depend on factors present in the MEL recipient cell as well as on the differentiated state of the human donor cell, suggesting that this system may be suitable for characterisation of mechanisms governing haematopoietic differentiation in man. PMID- 6929407 TI - Biotechnology company planned. PMID- 6929408 TI - Biotechnology and the production of proteins. PMID- 6929410 TI - Natural death in medical practice. PMID- 6929409 TI - Twice daily treatment with cephradine of infections in children. PMID- 6929411 TI - Bone sarcomas in 239Pu-treated mice. AB - Female ICR mice were injected with a monomeric form of 239Pu (180.1 kBq/kg) at the age of 10 weeks and during the long-term contamination the incidence of bone sarcomas was studied. Average survival of 100 control mice was 545 +/- 14 days, the 100 plutonium-given mice survived 420 +/- 10 d and 50 sarcoma-bearing animals 456 +/- 11 days. Most of the 61 induced sarcomas were located in the spine (70%) and in trabecular parts of the other bones. Among these 61 tumors there were 55 osteoblastic osteosarcomas, 4 immature undifferentiated sarcomas and 2 angiosarcomas. In 6 tumor-bearing mice metastases were observed in lungs, liver, intracranial cavity and in mediastinal lymph nodes. Among control mice only one osteogenic mandibular sarcoma was verified. The osteosarcoma incidence was evaluated with respect to the retained activity and cumulative average skeletal dose. The results were discussed and compared with data published by others. PMID- 6929412 TI - The favourable effect of immunotherapy on survival and the achievement of a second remission in acute myeloid leukaemia. PMID- 6929413 TI - Computed tomography and radionuclide brain scanning: comparison in evaluating metastatic lesions to brain. PMID- 6929417 TI - Women's liberation: effect on physician-patient relationship. PMID- 6929418 TI - Pheochromocytoma: diagnosis and management. PMID- 6929416 TI - Crisis intervention in private medical practice. PMID- 6929414 TI - Arteriovenous access for hemodialysis: utilizing polytetrafluoroethylene grafts. PMID- 6929415 TI - Terminally ill patients: assessment of physician attitudes within teaching institution. PMID- 6929419 TI - Electrocardiograms of the month. PMID- 6929420 TI - Disorganized shoulder joint. PMID- 6929421 TI - Anorectal gonococcal infection. PMID- 6929422 TI - Electric blanket hazard. PMID- 6929423 TI - Methylmalonic acid excretion in methylmalonic acidemia. PMID- 6929426 TI - Pancreatic pseudocyst with unusual complications: perforation of portal and splenic veins and hypersplenism. PMID- 6929424 TI - Recurrent diagphragmatic herniation: following gastric onlay reinforcement of esophageal rupture (Boerhaave syndrome). PMID- 6929425 TI - Gallbladder hydrops: complication of Kawasaki disease. PMID- 6929427 TI - Respiratory distress syndrome: past, present, and future. PMID- 6929428 TI - Physician and social security. PMID- 6929429 TI - Blood services in United States: status report. PMID- 6929430 TI - Dental health of the child and adolescent. PMID- 6929431 TI - Dental caries: diagnosis and treatment planning. PMID- 6929433 TI - Address to the New Zealand Dental Association regional meeting, Waitangi, 28 August 1979, by the Minister of Health the Honourable G.F. Gair. PMID- 6929432 TI - Improving poor partial-denture-bearing soft tissue by a periodontal surgical procedure. PMID- 6929434 TI - High-density lipoprotein (HDL) cholesterol in middle-aged joggers. AB - We have compared risk factors for coronary heart disease (CHD), including HDL cholesterol, in joggers and Rotarians aged 40 to 50 years. The only significant differences between the groups were lower resting heart rates and higher HDL cholesterol levels in the joggers. It appears that a considerable amount of exercise is required to raise HDL cholesterol levels. Significant elevation of HDL cholesterol was confined to those joggers who had either been running for at least four years or who were running 56 km per week or more. PMID- 6929435 TI - Perinatal mortality in Southland. AB - A review of Southland's perinatal mortality was undertaken from 1971 to 1977 and included 237 deaths with a post mortem rate of 90 percent. During this period, the perinatal mortality rate fell to below the national average. Prematurity remains the most important single factor. Seventy-four percent of confinements are attended solely by general practitioner obstetricians. Fetal monitoring of high risk pregnancies in labour markedly reduces the intrapartum death rate of mature babies. PMID- 6929436 TI - Aleppo boil in Christchurch: a case of cutaneous leishmaniasis. PMID- 6929437 TI - Serum copper and zinc in rheumatoid arthritis and osteoarthritis. AB - Serum copper, zinc and caeruloplasmin levels were measured in 49 patients with active rheumatoid arthritis, in 33 patients with osteoarthritis and a group of blood donor controls. Serum copper and caeruloplasmin levels in the osteoarthritic patients were significantly higher and serum zinc levels significantly lower than in the blood donor controls. Although these differences could not be accounted for on the basis of age or drug administration neither did they correlate with a radiological grading of disease severity. Copper and caeruloplasmin levels were raised in the rheumatoid group as compared to both osteoarthritic and control groups. These were strong correlations between serum copper, caeruloplasmin, ESR and alpha 1 globulin levels in the rheumatoid patients. Although caeruloplasmin-bound copper accounted for most of the elevation in serum copper levels in the rheumatoid group, the calculated non caeruloplasmin bound copper level was also elevated in rheumatoid, as compared to osteoarthritic patients. Serum zinc levels in the rheumatoid group were lower than in the control group but not significantly different to those in the osteoarthritic group. PMID- 6929438 TI - Nitrofurantoin induced chronic pulmonary reaction: case report. PMID- 6929439 TI - New Zealanders and their diet. PMID- 6929440 TI - Where have all the people gone? The population datum for medical manpower requirements. PMID- 6929441 TI - Aural health in 227 Northland school and preschool children. AB - Two hundred and seventy-seven Northland school and preschool children were examined to determine the current incidence of chronic suppurative otitis media and middle ear effusion in the child population of one area. A reduction in incidence of CSOM from 10.5 percent in 1974 to 2.7 percent in 1978 is attributed to the successful mobile ear clinic's child health hearing conservation programme. The incidence of middle ear effusion would indicate that this condition may be less uncommon in Maori children than is generally believed. The value of impedance audiometry as a screening procedure is considered. PMID- 6929443 TI - Conduct of the Medical Council. PMID- 6929442 TI - Labetelol as a hypotensive agent compared to other sympatholytic or vasodilator agents. PMID- 6929444 TI - Rape crisis centre. PMID- 6929445 TI - The troublesome adolescent. PMID- 6929446 TI - National Children's Dental Health Week--Month--Year. PMID- 6929447 TI - Should your society advertise? PMID- 6929448 TI - Child abuse and what you should do about it. PMID- 6929450 TI - The troubled road to "access". PMID- 6929449 TI - Epidemiological survey of caries-related behavior in caries-free children. PMID- 6929451 TI - The challenge for a changing profession. PMID- 6929452 TI - The modus operandi of the DSSNY legislative effort. PMID- 6929457 TI - Teaching the disciplines of orthodontics in general practice residencies. PMID- 6929453 TI - Access program--north country style. PMID- 6929456 TI - Developing a multi-state preventive strategy for dental health promotion. PMID- 6929458 TI - Dentistry for the homebound. An inbound patient. PMID- 6929459 TI - Institute of Dental Research evaluates copper amalgams. PMID- 6929454 TI - Outreach--oral health care for nursing home residents. PMID- 6929455 TI - Cautions on capitation practice. PMID- 6929460 TI - The eruption tendency and changes of direction of impacted teeth following surgical exposure. AB - Surgical exposure may be an integral part of orthodontic treatment of impacted teeth. In some cases the surgical procedure alone results in eruption and alignment of such teeth. The nature of the mechanism that starts concomitantly with the removal of covering tissues is not known. The aim of this investigation was to study factors associated with eruption as well as the eruption route of impacted and unerupted teeth following surgical exposure. The material consisted of 542 impacted teeth in 389 patients. The findings given strong support to the hypothesis that forces within surrounding tissues act upon the exposed crown in such a way as to direct it toward the area where the tissues were removed. PMID- 6929461 TI - Actinomycosis involving a periapical cyst in the anterior maxilla. Report of a case. PMID- 6929462 TI - Technique and use of "corrected-axis" tomograms of the mandibular condyles. AB - In diagnosing and treating temporomandibular joint (TMJ) dysfunctions, the oral and maxillofacial surgeon can use the radiographic technique of "corrected-axis" lateral tomography of the mandibular condyles. The theory, technique, and equipment necessary for making "corrected-axis" lateral tomograms of the mandibular condyles are presented. Once familiar with this technique, the surgeon can educate the radiologist and technician if it is one with which they are unfamiliar. PMID- 6929463 TI - Arteriograms of the palatine arteries in normal and cleft palate dogs. AB - Arteriography was used to study the arterial distribution of the hard and soft palate in dogs with and without cleft palate. Selective catheterization of the maxillary arteries produced arteriograms of the palatine arteries. Surgical exposure of the left common carotid artery or the right femoral artery was used for entry into the arterial system. The control dogs demonstrated a normal number of foramina (one on each side) with cross communication of the terminal arteries. The presence of additional foramina on the left side of the cleft as compared with the right side indicates the possibility of greater vascularity unilaterally. These findings may be of clinical significance. PMID- 6929464 TI - Fracture of glenoid fossa following mandibular trauma. AB - A case of glenoid fossa fracture secondary to mandibular trauma is reported. Subjectively, this injury is characterized by pain in the temporomandibular region of the injured side and by mandibular function impotence. Objectively, there is disappearance of the mandibular condyle from the pretragic region, mandibular lateral deviation toward the fractured side, and premature occlusal contacts on the injured side. The injury can be definitively diagnosed only with a temporomandibular joint radiographic examination of them, which includes a lateral and front-back projection stratigraphy. The surgical techniques currently used in these cases are also discussed. PMID- 6929465 TI - The inheritance of recurrent aphthous stomatitis. Observations on susceptibility. AB - In an effort to determine the prevalence of recurrent aphthous stomatitis (RAS), 1,303 children from 530 families were interviewed. While over-all disease prevalence in the children was 39.2 percent, there was a sharp difference in those children younger than 5 years (19.7 percent) and those 5 years of age and older (48.3 percent). Moreover, the prevalence of the disease in the children was significantly affected by whether RAS was present in none, one, or both of the parents. These observations suggest that disease susceptibility may be a complex interaction between host and environment. PMID- 6929466 TI - Beta thalassemia minor and cleidocranial dysplasia: a rare combination of genetic abnormalities in one family. AB - Dentists frequently treat patients who have several coexisting disease processes. When genetic disorders of distinct and separate types are present in several members of one family, it is a finding of considerable interest. A family afflicted with beta thalassemia minor and cleidocranial dysplasia is discussed and their management is presented. Special emphasis must be placed on the inclusion of genetic counseling in the treatment plan of patients with genetically transmissible abnormalities. PMID- 6929467 TI - Pulpectomy: immediate root canal filling with calcium hydroxide. Concept and procedures. AB - From the clinical aspect the endodontic treatment is divided into two groups: (1) teeth with pulp vitality (biopulpectomy) and (2) pulpless teeth (necropulpectomy). The authors point out the necessity of knowing the clinical pathologic conditions and the macroscopic aspect of the dental pulp before endodontic treatment. They describe the clinical procedures that must be performed in cases when the tooth presents pulp vitality (biopulpectomy), emphasizing (1) the necessity of a field of operation in an aseptic condition; (2) the necessity of a noninjuring instrumentation; (3) the use of cytophylactic substances and not cytotoxic substances; and (4) the use of a root canal--filling technique that respects the limits of the pulp stump, employing calcium hydroxide, a substance that maintains its vitality and induces and accelerates the apical closure by hard-tissue deposition. PMID- 6929468 TI - Evaluation of methods of transport and cultivation of bacterial specimens from infected dental root canals. AB - Five different methods of transport and cultivation of bacteria from dental root canal specimens were evaluated. Bacteria were recovered from 29 percent of the specimens when they were transported in VMG IV and subcultured in PRAS medium or on the surface of blood agar in an anaerobic box. When a PRAS-peptone-yeast extract broth was used for transport and the specimens were initially subcultured in the broth, bacteria were recovered from 49 percent of the specimens. When fluid thioglycollate medium USP (BBL) and Clausen medium (Oxoid) were used for transport as well as for initial subculture, bacteria were recovered from 58 percent and 47 percent of the specimens, respectively. The high recovery of bacteria by these media could to a significant degree be ascribed to the use of the media for initial subculture of the specimens. Recovery of bacteria by fluid thioglycollate medium USP was as good or even better as with the more elaborate PRAS medium. Fluid thioglycollate medium USP in screw-capped vials requires no special equipment in the dental clinic and is recommended for use in routine dental practice. PMID- 6929469 TI - Reactions of guinea pig subcutaneous connective tissue following exposure to sodium hypochlorite. AB - Experiments aimed at determining which concentration of sodium hypochlorite should be used clinically to achieve optimal dissolving and bactericidal but nonirritating effect are reported. The results of in vivo experiments, with polyethylene tubes implanted in the backs of guinea pigs, show that there is no significant difference in inflammatory response between sodium hypochlorite solutions in the concentration range of 2 to 8 percent, pH 12, and sterile physiologic saline. PMID- 6929470 TI - A leaded apron for use in panoramic dental radiography. AB - The leaded aprons currently available for use during dental radiography do not protect the thyroid gland from radiation. Conventional aprons may produce artifacts when used with panoramic dental x-ray units. This study measures the dose reduction obtained with an experimental leaded apron designed for use with panoramic dental x-ray units. Skin exposures measured at the thyroid and at the sternum were reduced with the use of the apron. Films produced during the study were free from apron artifacts. PMID- 6929472 TI - Lateral periodontal cyst. PMID- 6929471 TI - Monostotic (craniofacial) fibrous dysplasia. PMID- 6929473 TI - May is hypertension month. PMID- 6929474 TI - NJSN response to Attorney General's Committee. PMID- 6929475 TI - The state of the State vis-a-vis the Nation. PMID- 6929476 TI - Stress. PMID- 6929477 TI - [Xeroradiography--an alternative to radiography?]. AB - The xeroradiographic system uses charged selenium coated plates in place of film. In medical radiology the system has been in use for some years, especially in mammary examinations. Medical xeroradiographic equipment is well suited for diagnostic use in orthodontics and oral surgery. A prototype for dental use has been developed in the USA. Intraoral cassettes are used in combination with a dental x-ray machine. Image quality is superior to conventional film. In the future, the use of xeroradiography in radiographic interpretations seems promising. PMID- 6929478 TI - [Cooperation between dental health service and nursing care. Interview with nurses taking part in dental health information]. PMID- 6929479 TI - [Acute lymphoblastic leukemia. Late testicular relapse associated with lymph node sarcoidosis]. PMID- 6929481 TI - Molecular structure and intermolecular interactions of N1'-methoxycarbonylbiotin methyl ester: a model for carboxybiotin. AB - The crystal structure of N1'-methoxycarbonylbiotin methyl ester, a model for N1' carboxybiotin, has been determined. The ureido carbonyl bond has more double bond (keto) character than does the corresponding bound in free biotin, which has single bond (enolate) character. In addition, there is an interesting intermolecular interaction between the ureido carbonyl oxygen and a methyl group. Comparison of the molecular structure and crystal packing with those of free biotin suggests that the coenzyme may have evolved with the incorporation of the ureido moiety because the electronic configuration of this region of the molecule is sensitive to N1' carboxylation. On decarboxylation, the ureido carbonyl bond becomes more polarized (C-O-), thereby facilitating the deprotonation of N1' and increasing its nucleophilicity. As a result, carboxylation can occur readily. On carboxylation, the carbonyl bond is depolarized (C = O), allowing the carboxylated coenzyme to interact with nonpolar groups and carboxylate them. Thus, the carboxylation and decarboxylation of biotin appear to act as a mechanistic switch, turning off and on the polarization of the ureido carbonyl bond as well as modulating the nucleophilicity of N1'. PMID- 6929480 TI - Chemical mechanisms for cytochrome P-450 hydroxylation: evidence for acylation of heme-bound dioxygen. AB - Using isotopic tracer methods, we have shown that dihydrolipoic acid (2,3 thioctic acid) acylates the distal oxygen of ferrous oxygenated Pseudomonas cytochrome P-450, forming a transient acyl peroxide intermediate that facilitates oxygen-oxygen bond cleavage. Single-turnover studies with 18O2 indicate one oxygen-18 atom incorporated into the carboxylate group of lipoic acid for each oxygen-18 inserted into the substrate, camphor, forming the product, exo-5 hydroxycamphor. Such a branching ratio for label indicates that water is initially released from an unlageled position and illustrates that the general P 450 mixed-function oxidase stoichiometry generates H218O from 18O2 only after multiple-turnover equilibration with the acylating carboxylate oxygen. Formation of an acyl peroxide state is a natural intermediate in peracid, "oxene", or radical mechanisms for methylene carbone oxygenation. PMID- 6929482 TI - Arogenate (pretyrosine) is an obligatory intermediate of L-tyrosine biosynthesis: confirmation in a microbial mutant. AB - Wild-type Brevibacterium flavum has been shown to possess arogenate dehydrogenase activity and to lack prephenate dehydrogenase, thereby providing presumptive evidence that arogenate (previously named "pretyrosine") is an obligatory intermediate of L-tyrosine biosynthesis. A similar enzymological pattern has been discerned in extracts made from wild-type cultures of various species of cyanobacteria. Application of rigorous molecular genetic criteria in confirmation of the exclusive role of arogenate in L-tyrosine synthesis was made possible by the isolation of an auxotrophic mutant exhibiting a nutritional requirement for L tyrosine. The mutant was found to lack activity for arogenate dehydrogenase and to accumulate substantial amounts of arogenate behind the mutant block during starvation for L-tyrosine. PMID- 6929483 TI - Selective oxidation of cysteine and methionine in normal and senile cataractous lenses. AB - The oxidation state of methionine and cysteine in normal and cataractous lenses is reported. In young lenses no oxidation was detected in any protein fraction examined. Only the intrinsic membrane fraction and membrane-related components showed evidence of oxidation in old (60-65 years of age) normal lenses. However, in a similar age group, with the development of cataract, progressive, dramatic changes were observed. With severe cataracts, 60% or more of the methionine in membrane-associated components was found in the methionine sulfoxide form, and methionine sulfone was observed in one case. Most of the cysteine was found oxidized to either the disulfide form or putative cysteic acid. Mixed disulfides with glutathione were observed. Oxidative changes in soluble components as illustrated by alpha-crystallin occurred more gradually. The data clearly support the viewpoint that extensive oxidation of lens proteins occurs with cataract and that it begins at the lens fiber membrane. PMID- 6929485 TI - Three-dimensional crystals of membrane proteins: bacteriorhodopsin. AB - The intrinsic membrane protein bacteriorhodopsin has been crystallized by salt precipitation after solubilization by octyl glucoside. Two different crystal forms were obtained, depending on the nature of the salt used and the pH. Needles formed in the presence of sodium phosphate and in ammonium sulfate solutions above pH 4.8. Cubes appeared in sodium citrate solutions or ammonium sulfate. Unlike the cubic crystals, the birefringent needles showed strong linear dichroism, which allowed determination of the orientation of the chromophore's transition moment. The procedure described here may be of general use in crystallographic studies of membrane proteins. PMID- 6929484 TI - Could poly(A) align the splicing sites of messenger RNA precursors? AB - In general, poly(A)-mRNA appears to be derived from larger nuclear RNA precursors. The maturation of these precursors involves excision of sequences of variable length from within the molecule and splicing of the remaining structural and coding sequences. The mechanism by which this process occurs is not known. It does not appear to operate solely through the recognition of a defined primary sequence or through the formation of a consistent secondary structure. We propose an alternative model in which poly(A) facilitates the splicing event by promoting the formation of triple-stranded structures within the mRNA precursor. PMID- 6929486 TI - Site-specific phosphorylation of the alpha subunit of eukaryotic initiation factor eIF-2 by the heme-regulated and double-stranded RNA-activated eIF-2 alpha kinases from rabbit reticulocyte lysates. AB - The site specificity of phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF-2alpha) by the heme-regulated and double-stranded RNA activated eIF-2alpha kinases were compared by phosphopeptide mapping. eIF-2alpha was maximally phosphorylated in vitro with [gamma-(32)P]ATP and either crude or partially purified preparations of the kinases. (32)P-Labeled eIF-2alpha was isolated by electrophoresis in sodium dodecyl sulfate/polyacrylamide gels. The fixed, stained, and dried polypeptide band was excised and then exhaustively digested directly in the gel slice with one of several proteases (trypsin, chymotrypsin, subtilisin, or thermolysin); the resultant [(32)P]phosphopeptides were analyzed by one-dimensional chromatography or by two-dimensional chromatography and high-voltage electrophoresis. In addition, limited proteolysis of [(32)P]eIF-2alpha contained in fixed, dried, and stained gel slices was achieved with Staphylococcus aureus protease V8, chymotrypsin, or subtilisin, and the partial (32)P-labeled cleavage products were analyzed by gel electrophoresis. Each protease produced distinct and reproducible [(32)P]phosphopeptide profiles after partial or exhaustive proteolysis of [(32)P]eIF-2alpha. With a given protease, identical [(32)P]phosphopeptide patterns were obtained whether eIF 2alpha was phosphorylated by the heme-regulated or the double-stranded RNA activated kinase. These data indicate that, in vitro, the kinases phosphorylate sites on eIF-2alpha that are identical or proximally located in the primary sequence. In this report we also provide preliminary evidence that the two eIF 2alpha kinases activated in lysates by heme deficiency or double-stranded RNA phosphorylate site(s) of endogenous eIF-2alpha that are similar, if not identical, to the sites phosphorylated in vitro with partially purified eIF 2alpha kinase(s) and eIF-2. PMID- 6929487 TI - Enrichment of estradiol-receptor complexes in a transcriptionally active fraction of chromatin from MCF-7 cells. AB - We have examined the interaction of the estradiol receptor molecule with chromatin in MCF-7 cells, a human breast tumor cell line responsive to estradiol. Receptor was found associated with the various nucleosomal products produced by digestion with micrococcal nuclease. In order to determine whether these receptor binding sites were distributed in a random or nonrandom manner within the chromatin, we have fractionated MCF-7 cell chromatin into transcriptionally active and inactive fractions by limited micrococcal nuclease digestion followed by Mg(2+) precipitation. A comparison of the Mg(2+)-soluble and insoluble chromatin fractions showed that the Mg(2+)-soluble fraction: (i) was composed predominantly of mononucleosomes; (ii) was enriched in nonhistone proteins; (iii) apparently lacked histone H1; (iv) was enriched approximately 5-fold in transcribed sequences as measured by a cDNA probe to cytoplasmic poly(A)-RNA sequences; and (v) was depleted at least 5-fold of globin sequences, which is presumably a nontranscribed gene in these cells. When these cells were stimulated with beta-[(3)H]estradiol, the Mg(2+)-soluble fraction showed a significant enrichment in chromatin-bound estradiol receptor: the Mg(2+)-soluble mononucleosomes showed a 3- to 4-fold enrichment and the di- and trinucleosomes, a 7- to 19-fold enrichment, when compared to the corresponding subunits in the Mg(2+)-insoluble chromatin fraction. This cofractionation of chromatin enriched in transcribed sequences and bound estradiol receptor indicated that receptor binding to MCF-7 cell chromatin was not random but, rather, occurred preferentially in specific regions of the chromatin. PMID- 6929488 TI - Induction of pyruvate carboxylase apoenzyme and holoenzyme in 3T3-L1 cells during differentiation. AB - The specific activity of pyruvate carboxylase [pyruvate:carbon-dioxide ligase (ADP-forming); EC 6.4.1.1] in 3T3-L1 cells increases approximately 20-fold when these cells differentiate to an adipocyte-like form [Mackall, J. C. & Lane, M. D. (1977) Biochem. Biophys. Res. Commun. 79, 720-725]. A specific antibody to the purified rat liver enzyme quantitatively precipitated pyruvate carboxylase from 3T3-L1 crude homogenates. Use of this immunological technique permitted us to demonstrate that the increase in pyruvate carboxylase activity is due to an increase in the intracellular concentration of the enzyme. The content of pyruvate carboxylase in differentiated 3T3-L1 cells is sufficiently high (1-2% of total protein) that the increase in this large protein (subunit M(r) = 130,000) can be visualized when 3T3-L1 crude extracts are subjected to electrophoresis on sodium dodecyl sulfate/polyacrylamide gels. When 3T3-L1 cells differentiated in the presence of avidin, they contained less than 5% of the pyruvate carboxylase activity of cells that differentiated in the absence of avidin. However, the immunoprecipitable pyruvate carboxylase content of the avidin-treated cells was essentially the same as that of cells that differentiated without avidin. Full activity of the enzyme was rapidly restored in the avidin-treated cells upon the addition of excess biotin. The recovery of activity was closely correlated with the incorporation of [(14)C]biotin into immunoprecipitable pyruvate carboxylase. The rapidity with which the activity was restored and the insensitivity of the process to inhibitors of protein synthesis strongly suggest that the apoenzyme of pyruvate carboxylase accumulates during differentiation in the presence of avidin. PMID- 6929489 TI - Mitochondria and sarcoplasmic reticulum as model targets for neurotoxic and myotoxic phospholipases A2. AB - Certain neurotoxins and myotoxins from snake venoms have phospholipase A(2) activity (phosphatide 2-acylhydrolase, EC 3.1.1.4), which appears to be necessary for their toxicity. Several of these toxins inhibit the net uptake of Ca(2+) into sarcoplasmic reticulum vesicles and brain mitochondria. We have obtained evidence that the ability to inhibit this Ca(2+) uptake is a mechanistically relevant correlate of the toxicity of these proteins rather than being just a nonspecific consequence of their phospholipase A(2) activity. Two of the toxins, beta bungarotoxin and notexin, had 5% and 50%, respectively, of the phospholipase A(2) activity of IVa phospholipase A(2)(a nontoxic enzyme), but beta-bungarotoxin was as effective as IVa in inhibiting Ca(2+) uptake into brain mitochondria and notexin was more effective. Each of the myotoxic enzymes substantially inhibited Ca(2+) uptake into sarcoplasmic reticulum, notexin being the most effective in this regard. This ability correlated better with their myotoxic potency than with their phospholipase A(2) activity. beta-Bungarotoxin lost its toxicity but not its measurable phospholipase A(2) activity after modification with ethoxyformic anhydride in the presence of dihexanoylphosphatidylcholine. The modified toxin also lost most of its ability to inhibit Ca(2+) uptake into sarcoplasmic reticulum and brain mitochondria. Sarcoplasmic reticulum vesicles reconstituted from solubilized sarcoplasmic reticulum retained their sensitivity to notexin. PMID- 6929490 TI - Inhibition of preprotein processing in ascites tumor lysates by incorporation of a leucine analog. AB - Leucine analogs were tested in the Krebs II ascites cell-free translation system for the ability to inhibit preprotein cleavage by replacing leucine in nascent chains of bovine preprolactin, rat preprolactin, human placental prelactogen (pre hPL), and pre-alpha subunit of human chorionic gonadotropin (alpha-hCG). In the absence of analog, ascites microsomal membranes cleaved these preproteins to their mature forms and sequestered the processed products. Also, two asparagine residues in alpha-hCG were glycosylated. When 4 mM beta-DL-hydroxyleucine was added to the lysate instead of L-leucine, cotranslational processing and sequestration of both species of preprolactin and pre-hPL were inhibited. Sequential Edman degradation confirmed that pre-hPL was not cleaved. The inhibition of processing by beta-hydroxyleucine resulted from its incorporation into protein. This was shown by reversal of the effect by addition of leucine and by inhibition of [(3)H]leucine incorporation into protein. Of significance, the processing of pre-alpha-hCG was less sensitive to beta-hydroxyleucine because its prepeptide contains only four scattered leucine residues, whereas the presegments of hPL and the prolactins contain six to eight clustered leucine residues. These experiments demonstrate that translocation and processing of secretory proteins require structural features determined by the primary amino acid sequence. PMID- 6929491 TI - Evidence for four different polymerization sites involved in human fibrin formation. AB - The mechanism of association and the organization of human fibrin were studied by using affinity chromatography. Insolubilized fibrinogen, fibrin monomer, and crosslinked fibrin were used to localize the binding sites on fibrinogen and fibrin derivatives. Four different polymerization sites have been distinguished. A binding site ("a"), available without thrombin action, is present on the fibrinogen fragment D domain. The complementary ("A") is inoperative in fibrinogen and requires thrombin for activation; it is located on the fibrinogen NH2-terminal domain. A third polymerization site ("b") appears to be formed by the alignment of the fragment D domains on two fibrin monomer molecules upon polymerization; this site functions without thrombin mediation and the alignment is stabilized by the Factor XIIIa-catalyzed crosslink bonds. The "b" site is complementary to another thrombin-activated site ("B") on the fibrinogen NH2 terminal domain. The two thrombin activable sites, "A" and "B", are distinguishable, although they are located in the same fibrinogen domain. PMID- 6929492 TI - Characterization of globin domains: heme binding to the central exon product. AB - We have prepared and isolated the peptide fragments coded for by the three exons of the human beta-globin gene, using the arginine-specific protease clostripain (EC 3.4.22.8). The region encoded by the central exon (amino acid residues 31 104) contains an arginine at position 40. This site was less susceptible to cleavage than the two sites that correspond to the exon-intron boundaries, and the isolated central fragment was an approximately equimolar mixture of the entire central fragment, beta(o) (31-104), and the somewhat smaller fragment contained within it, beta(o) (41-104). This central fragment mixture bound heme stoichiometrically and tightly at micromolar concentrations, generating a strong Soret absorption band as well as a characteristic absorption band in the visible spectrum. The Soret band occurred at the same wavelength and had the same shape as in hemoglobin, exhibiting an intensity greater than (2/3) that achieved when native intact beta globin is reconstituted with heme. Nearly the full intensity was regained when an equivalent of heme was added to the unfractionated digest, suggesting that the noncovalently associated side fragments add precision to the fit of the heme pocket. Three controls were used in establishing the specificity of heme binding to the central fragment mixture. Similar, but preliminary, experiments have also been undertaken with alpha globin. A clostripain digest containing alpha(o) (1-31) and alpha(o) (32-141) bound heme, yielding a Soret band identical to that observed in alpha subunits reconstituted from the native globin chains and heme. Measurements of circular dichroism spectra as indices of secondary structure suggested a role for the side exon products in the acquisition of the native three-dimensional structure of hemoglobin. These experiments confirm a prediction of W. Gilbert that the product of the central exon of the globin gene is a complete functional domain that binds heme tightly and specifically. PMID- 6929493 TI - Structurally unique basic protein coextracted with histones from calf thymus chromatin. AB - A histone-like protein that is rich in alanine and lysine (protein AK) has been obtained in homogeneous form by high-resolution gel filtration of H2SO4 extracts of calf thymus chromatin. Protein AK: (i) migrates as a single band in polyacrylamide gel electrophoresis in both acetic acid/urea and sodium dodecyl sulfate; (ii) is a basic protein; (iii) lacks tryptophan; (iv) is not extracted from chromatin with 0.35 M NaCl; and (v) is not soluble in 0.75 M HClO4. Protein AK is distinguished from the high-mobility group (HMG) proteins on the basis of these latter solubility characteristics and from the histones and protein A24 on the basis of amino acid composition and distribution of tryptic peptides in two dimensional chromato-electrophoresis. In addition, protein AK is distinguished from the HMG proteins, the histones, and protein A24 on the basis of its mobility in two polyacrylamide gel electrophoresis systems. The amino acid composition of protein AK resembles that of HU, a basic DNA-binding protein found in Escherichia coli. PMID- 6929495 TI - Magnetic fields produced by steady currents in the body. AB - The magnetic fields produced by naturally occurring steady currents in the body were measured by using a new magnetic gradiometer in a magnetically shielded room. A field of 0.1 micro G/cm with reproducible pattern was seen over the head and over the limbs, whereas the field over the torso proper was weaker (except over the abdomen). Most of the field over the head is produced by electrical sources associated with the hair follicles of the scalp; this field is produced only as a response to touching or pressing the scalp, in regions where the hair is dense. Most of the field over the limbs is produced by electrical sources associated with the muscles. The field over the forearm, studied in detail, was often present spontaneously; when absent, it could be induced by mild twisting and rubbing. On the basis of auxiliary experiments involving electrolytes, a general mechanism for generation of steady current in the body is suggested. In this mechanism, the steady current is generated by a nonclosed or a nonuniform polarized layer across an elongated semipermeable membrane such as a muscle fiber; the nonuniform polarization is due to a gradient of extracellular K+ along the membrane. PMID- 6929494 TI - Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo. AB - Conserved DNA sequence elements of putative regulatory functions were deleted from the prelude region of a sea urchin H2A histone gene. For this, the wild-type H2A gene of the 6-kilobase histone DNA repeat unit was replaced by various mutant H2A genes by cloning. The effects of the manipulation on H2A mRNA synthesis were studied by injection of the mutant DNAs into centrifuged Xenopus oocytes. The unmanipulated H2B gene residing within the same repeat unit provided a suitable internal control for these studies. Deletion of the T-A-T-A-A-A-T-A motif, once thought to be the functional equivalent of the bacterial Pribnow box, did not abolish transcription of the gene; instead, a number of novel mRNA 5' termini were generated. We argue that the T-A-T-A-A-A-T-A motif is a specificity element, a selector of eukaryotic gene transcription. Deletion of the "cap-sequence," 5' pyrimidine-C-A-T-T-C-purine 3' and most of the mRNA leader sequence did not abolish transcription but created yet another mRNA 5' terminus. In contrast to these deletions, which are both down-mutations, deletion of H2A gene-specific conserved DNA sequences upstream from the T-A-T-A-A-A-T-A motif enhanced mRNA synthesis. A hypothesis for the function of these DNA sequences as eukaryotic promoter elements is discussed. PMID- 6929496 TI - Modulation of membrane protein lateral mobility by polyphosphates and polyamines. AB - The lateral mobility of fluorescein-labeled membrane glycoproteins was measured in whole unlysed erythrocytes and erythrocyte ghosts by the technique of "fluorescence redistribution after fusion." Measurements were made on polyethylene glycol-fused cell pairs in which only one member of the couplet was initially fluorescently labeled. Diffusion coefficients were estimated from the rate of fluorescence redistribution determined from successive scans with a focused laser beam across individual fused pairs. This technique allows for the analysis of diffusion within cell membranes without the possible damaging photochemical events caused by photobleaching. It was found that lateral mobility of erythrocyte proteins can be increased by the addition of polyphosphates (i.e., ATP and 2,3-diphosphoglycerate) and decreased by the addition of organic polyamines (i.e., neomycin and spermine). This control is exerted by these molecules only when they contact the cytoplasmic side of the membrane and is not dependent upon high-energy phosphates. Microviscosity experiments employing diphenylhexatriene demonstrated no changes in membrane lipid state as a function of these reagents. Our results, in conjunction with data on the physical interactions of cytoskeletal proteins, suggest that the diffusion effector molecules alter the lateral mobility of erythrocyte membrane proteins through modifications of interactions in the shell, which is composed of spectrin, actin, and component 4.1. PMID- 6929497 TI - Variability of the magnetic moment of carbon monoxide hemoglobin from carp. AB - Deionized carp carbon monoxide hemoglobin in distilled water or in bis(2 hydroxyethyl)imino-tris(hydroxymethyl)methane or Tris buffer exhibits a slight but significant paramagnetism. This is most clearly demonstrated by the decrease in this paramagnetism that is caused by the addition of inositol hexaphosphate to this protein in the former buffer at pH 6.3-6.4. No such effect is seen when inositol hexaphosphate is added to carp cyanomethemoglobin, demonstrating that the change observed with carbon monoxide derivative is not due to a modification in the diamagnetic properties of the protein. PMID- 6929498 TI - Polyamine and differentiation: induction of ornithine decarboxylase by parathyroid hormone is a good marker of differentiated chondrocytes. AB - The activity of ornithine decarboxylase (OD-Case:L-ornithine carboxy-lyase, EC 4.1.1.17) in rabbit costal chondrocytes in culture increased markedly after addition of parathyroid hormone (PTH), reaching a maximum 4 to 5 hr after PTH addition. The increase in ODCase activity was followed by increase in the intracellular concentrations of polyamines, especially putrescine, which increased in 6 hr to about 3-fold that of untreated cultures. The induction of ODCase by PTH was not observed in L, 3T3, HeLa, buffalo rat liver, or BHK cells. Retinyl acetate and retinoic acid both inhibited expression of the differentiated phenotype of chondrocytes by rabbit costal chondrocytes in culture within 3 days after their addition, as judged by morphological change and decrease in sulfate incorporation into glycosaminoglycans but did not inhibit cell proliferation. PTH could not induce an increase in ODCase in de-differentiated cells that had been pretreated with retinyl acetate or retinoic acid for 3 days. but 4 days after removal of the retinoids, these de-differentiated cells regained the ability to synthesize ODCase in response to PTH. These facts suggest that the induction of ODCase and the formation of putrescine by PTH are good markers of the differentiated phenotype of cultured chondrocytes. PMID- 6929500 TI - Temperature-sensitive tumorigenicity of cells transformed by a mutant of Moloney sarcoma virus. AB - Normal rat kidney cells were nonproductively infected either with CP27, a mutant of Moloney sarcoma virus that is temperature-sensitive for maintenance of transformation, or with the parental wild-type virus. The nonproducer cells were inoculated into the tails of athymic nude mice that were subsequently incubated at 28 or 36 degrees C. CP27-infected cells induced tumors only at 28 degrees C, whereas cells infected with wild-type Moloney sarcoma virus were tumorigenic at both temperatures. Tumors induced at 28 degrees C by wild-type virus-infected cells grew faster after shift of the mice to 36 degrees C. In contrast, tumors induced by CP27-infected cells regressed upon shift to 36 degrees C, indicating that continuous expression of viral functions is required for persistence and growth of the tumors. After regression, secondary tumor growth was observed late after upshift of temperature-sensitive tumors. Cells recovered from these late appearing tumors were tumorigenic at the nonpermissive temperature, and tumors induced by these cells did not regress after upshift. Virus rescued from these recovered cells retained the temperature-sensitivity for focus formation, indicating that the occurrence of the phenotypically wild-type cells was due to host cell modifications rather than to reversion of the CP27 genome. PMID- 6929499 TI - Intracellular protein topogenesis. AB - Concurrently with or shortly after their synthesis on ribosomes, numerous specific proteins are unidirectionally translocated across or asymmetrically integrated into distinct cellular membranes. Thereafter, subpopulations of these proteins need to be sorted from each other and routed for export or targeted to other intracellular membranes or compartments. It is hypothesized here that the information for these processes, termed "protein topogenesis," is encoded in discrete "topogenic" sequences that constitute a permanent or transient part of the polypeptide chain. The repertoire of distinct topogenic sequences is predicted to be relatively small because many different proteins would be topologically equivalent-i.e., targeted to the same intracellular address. The information content of topogenic sequences would be decoded and processed by distinct effectors. Four types of topogenic sequences could be distinguished: signal sequences, stop-transfer sequences, sorting sequences, and insertion sequences. Signal sequences initiate translocation of proteins across specific membranes. They would be decoded and processed by protein translocators that, by virtue of their signal sequence-specific domain and their unique location in distinct cellular membranes, effect unidirectional translocation of proteins across specific cellular membranes. Stop-transfer sequences interrupt the translocation process that was previously initiated by a signal sequence and, by excluding a distinct segment of the polypeptide chain from translocation, yield asymmetric integration of proteins into translocation-competent membranes. Sorting sequences would act as determinants for posttranslocational traffic of subpopulations of proteins, originating in translocation-competent donor membranes (and compartments) and going to translocation-incompetent receiver membranes (and compartments). Finally, insertion sequences initiate unilateral integration of proteins into the lipid bilayer without the mediation of a distinct protein effector. Examples are given for topogenic sequences, either alone or in combination, to provide the information for the location of proteins in any of the intracellular compartments or for the asymmetric orientation of proteins and their location in any of the cellular membranes. Proposals are made concerning the evolution of topogenic sequences and the relationship of protein topogenesis to the precellular evolution of membranes and compartments. PMID- 6929502 TI - Classification of cultured mammalian cells by shape analysis and pattern recognition. AB - We have developed a method for classifying cultured cells on the basis of shape characteristics. High-resolution optical information on three-dimensional shape was obtained by anodic oxide interferometry. Each interference order formed in a cell was considered as a closed figure; measurement of 37 mathematical descriptors was carried out for each figure. The individual cells were classified according to the values of their descriptors. We used standard principles of pattern recognition, such as hierarchical cluster analysis and nearest neighbor analysis, as a basis for ordering the cells into groups. Alternatively, linear discriminant functions could be used, but they provided only a slight improvement in correct classification of the cells. We anticipate that the method will be appropriate for classification of cultured cell lines and for determination of the magnitude and direction of cell shape changes implicated in various biological processes. PMID- 6929501 TI - Inability of serum from abetalipoproteinemic subjects to stimulate proliferation of human smooth muscle cells and dermal fibroblasts in vitro. AB - Serum from two patients with abetalipoproteinemia, a rare disorder of lipid metabolism characterized by the absence of chylomicrons and very low density and low density lipoproteins, did not stimulate the proliferation and growth of human smooth muscle cells or dermal fibroblasts in vitro as effectively as normal serum. The growth-promoting activity of this serum was comparable to that observed for lipoprotein-deficient plasma from normolipidemic subjects. Although the mitogenic effect of abetalipoproteinemic serum was improved with supplementation of low density lipoproteins, it was still about half the activity achieved with normal serum. However, the growth-promoting activity of this serum was completely restored to normal levels after addition of a lysate of normal platelets. In contrast, the mitogenic activity of lipoprotein-deficient plasma remained unchanged after addition of a lysate from abetalipoproteinemic platelets, whereas a similar supplementation of normal platelets completely restored its growth-promoting activity to normal. Thus, the inability of abetalipoproteinemic serum to promote growth appears to be due both to a deficiency of a platelet-releasable growth factor(s) and to the absence of serum lipoproteins. PMID- 6929504 TI - Lateral diffusion of membrane lipids and proteins during the cell cycle of neuroblastoma cells. AB - The fluorescence photobleaching recovery method has been used to determine the lateral mobilities of membrane lipids and proteins during the cell cycle of synchronized C1300 mouse neuroblastoma cells (clone Neuro-2A). As probes for lipid mobility, 3,3'-dioctadecylindocarbocyanine iodide and a fluorescein-labeled analog of ganglioside GM1 were used. Membrane proteins were labeled with rhodamine-labeled rabbit antibodies against mouse E14 cells. For both lipid probes the diffusion coefficients reach a minimum in mitosis, increase 2- to 3 fold during G1, remain constant at maximal values during S, and decrease again shortly before mitosis. Membrane proteins also exhibit minimum diffusion coefficients in mitosis, followed by a similar rise in G1. However, as cells proceed through S and G2, the lateral mobility of the membrane proteins gradually decreases. It is argued that lipid mobility is controlled by the fluidity of the membrane lipid matrix whereas protein mobility is governed also by other constraints. PMID- 6929503 TI - Glyoxylate cycle in toad urinary bladder: possible stimulation by aldosterone. AB - A homogenate of the toad urinary bladder epithelial cell layer has the two enzymatic activities unique to the glyoxylate cycle--isocitrate lyase (threo-Ds isocitrate glyoxylate-lyase, EC 4.1.3.1) and malate synthase [L-malate glyoxylate lyase (CA-acetylating), EC 4.1.3.2]--as well as the capacity to carry out CN insensitive palmitoyl-CoA oxidation. When tissue is incubated in the presence of a fatty acid substrate, tissue glycogen levels increase. Additionally, in the presence of aldosterone, glycogen levels are higher. These data demonstrate the presence of glyoxylate cycle enzymes in tissue of a higher animal and raise the possibility that such tissue can convert lipid to carbohydrate. PMID- 6929505 TI - Trypanosoma brucei brucei: inhibition of glycosylation of the major variable surface coat glycoprotein by tunicamycin. AB - Trypanosoma brucei brucei incorporates D-[3H]mannose into protein in vitro in a medium we describe here. The label appears entirely in glycoproteins with approximately 90% in the major variable surface coat glycoprotein (VSCG). Incorporation is linear for 60 min and usually continues for an additional 30 min although at a decreased rate. In the same medium incorporation of L-[14C]serine is linear for 90 min. Incorporation of [3H]mannose is completely inhibited by tunicamycin at concentrations above 100 ng/ml, indicating that the label is being added as part of an N-linked oligosaccharide. This is reflected by a 5% decrease in the apparent molecular weight of VSCG on sodium dodecyl sulfate/polyacrylamide gel electrophoresis. Cycloheximide inhibits incorporation of both mannose and serine, although the rates and extent of inhibition differ. Based on the effects of tunicamycin or cycloheximide on incorporation of either precursor, we suggest that N-linked glycosylation occurs subsequent to synthesis of the VSCG polypeptide. PMID- 6929506 TI - Progesterone induces a rapid increase in [Ca2+]in of Xenopus laevis oocytes. AB - Progesterone causes a rapid increase in the intracellular free calcium level in fully grown amphibian oocytes. When albino Xenopus laevis oocytes were microinjected with the Ca-specific photoprotein aequorin, the calcium-induced luminescence from this protein increased at 40-60 sec after the addition of progesterone and returned to the control level within 5-6 min. No further change in the aequorin glow could be detected through the remainder of the maturation period. This transient increase in cytoplasmic free calcium may be involved in controlling the resumption of oocyte maturation. PMID- 6929507 TI - In vitro metabolism of 25-hydroxyvitamin D3 by isolated rat kidney cells. AB - Cells were dispersed from rat kidney after enzymatic digestion of the extracellular matrix. When the cells were suspended in a serum-free medium and incubated with (3)H-labeled 25-hydroxyvitamin D(3) (25-OH-D(3)) several polar metabolites, including 1,25-(OH)(2)[(3)H]D(3) and 24,25-(OH)(2)[(3)H]D(3) were produced. The specific activities of the 25-OH-D(3):1- and 24-hydroxylases in isolated rat kidney cells were 10-100 times greater than in avian kidney homogenates. The rates of production of 1,25-(OH)(2)D(3) and 24,25-(OH)(2)D(3) were linear over a wide range in cell densities (0.65-5.0 x 10(6) cells per ml) and substrate concentrations (3.5-70 nM). The rate of production of 24,25 (OH)(2)[(3)H]D(3) from 25-OH-[(3)H]D(3) by cells isolated from rats fed control diet was linear with time for up to 30 min, while the synthesis of 1,25 (OH)(2)[(3)H]D(3) was linear for over 90 min. The specific activity of the 25-OH D(3):1-hydroxylase was increased in kidney cells from vitamin D-deficient rats (11.5 fmol/min per 10(6) cells) as well as calcium-deficient rats (8.1 fmol/min per 10(6) cells) when compared to cells from rats fed the control diet (2.0 fmol/min per 10(6) cells). Also, the specific activity of the 25-OH-D(3):24 hydroxylase was reduced in cells from the vitamin D-deficient rats (<0.2 fmol/min per 10(6) cells) and calcium-deficient rats (5.1 fmol/min per 10(6) cells) compared to the controls (15.2 fmol/min per 10(6) cells). On the basis of these results, as well as previous in vivo studies, we conclude that the metabolism of 25-OH-D(3) by freshly isolated rat kidney cells reflects the in vivo activities of the renal vitamin D-metabolizing enzymes and may prove useful as an assay. PMID- 6929509 TI - Proteins iodinated by the chloramine-T method appear to be degraded at an abnormally rapid rate after endocytosis. AB - Proteins labeled with either (3)H by reductive methylation or (125)I by the chloramine-T method were incubated with Xenopus laevis oocytes; the incorporation and acid precipitability of the proteins were then studied. The uptake rates of both specifically incorporated (vitellogenin) and nonspecifically incorporated proteins (bovine serum albumin and X. laevis serum proteins lacking albumin) were not influenced by the method of labeling. However, (125)I-labeled proteins were apparently degraded at rates far exceeding their (3)H-labeled counterparts, based on the generation of acid-soluble radioactivity. Thus, after a 3-hr incubation, 3 5 times more (125)I-labeled bovine serum albumin and X. laevis serum proteins lacking albumin were degraded than the corresponding (3)H-labeled proteins (95% compared to 30% and 75% compared to 15%, respectively), whereas after a 24-hr incubation, the degradation of (125)I-labeled vitellogenin was 15 times greater than that of [(3)H]vitellogenin labeled in vivo (60% compared to 4%). Moreover, examination of the relative amounts of (3)H- compared to (125)I-labeled bovine serum albumin deposited into the exogenously derived yolk platelet compartment of the oocyte revealed 7 times more acid-precipitable (3)H-labeled protein, indicating that the observed discrepancies were not due to reincorporation of the (3)H-labeled ligands. Passage of dissolved oocytes previously exposed to (125)I labeled bovine serum albumin (chloramine-T method) over a column of Bio-Gel P-10 revealed some breakdown of bovine serum albumin to intermediate molecular weight components and the presence of a large amount ( approximately 90%) of labeled low molecular weight compounds, which analysis showed to be 72% free iodine. The evolution of either iodotyrosine or free iodine would nevertheless be perceived as protein degradation by most analytical procedures (e.g., acid precipitation or autoradiography). We conclude, therefore, that apparent degradation rates observed for endocytotically incorporated proteins may vary depending on the method used to label the protein and caution should be exercised when interpreting results obtained with labeled, particularly chloramine-T labeled, proteins. PMID- 6929510 TI - Autosomal dominant aniridia: probable linkage to acid phosphatase-1 locus on chromosome 2. AB - Maximum likelihood analysis for linkage between autosomal dominant aniridia and 12 biochemical and serological markers in a single large family showed a probable linkage between autosomal dominant aniridia and the enzyme acid phosphatase-1. The presence of an autosomal dominant aniridia gene linked to acid phosphatase-1 on chromosome arm 2p and the existence of an aniridia syndrome resulting from deletion of band 13 of the short arm of chromosome 11 establishes a chromosome basis for genetic heterogeneity of aniridia phenotypes. PMID- 6929508 TI - Control of differentiation of a mammary cell line by lipids. AB - A rat mammary cell line (LA7) undergoes spontaneous differentiation into domes due to production of specific inducers by the cells. Some of these inducers may be lipids, and we show that lipids regulate this differentiation as both inducers and inhibitors. One inhibitor is the tumor promoter tetradecanoyl-13 phorbol 12 acetate. The inducers are saturated fatty acids of two groups: butyric acid and acids with chain lengths from C13 to C16, especially myristic acid (C14). Other inducers are myristoyl and palmitoyl lysolecithins, myristic acid methyl ester, and two cationic detergents with a tetradecenyl chain. We propose that the lipids with a C14-C16 alkyl chain affect differentiation by recognition specific receptors through their alkyl chains and that the effects obtained depend on the head groups. These lipids may be physiological regulators in the mammary gland. PMID- 6929512 TI - During ontogeny, Ia-bearing accessory cells are found early in the thymus but late in the spleen. AB - The ontogeny of Ia-bearing accessory cells was studied in mice. Ia-bearing adherent cells from the thymus, consisting predominantly of macrophages, were found from birth. These adherent cells were able to present antigen, as measured by their ability to induce immune T-cell proliferation. In contrast, Ia-bearing adherent cells from the spleen were not found until the second week of life, and their antigen-presentation function was not present until later. The differential ontogeny of Ia-bearing accessory cells at these sites may be important in both development of immune competence and the restriction of autoimmunity. PMID- 6929513 TI - Prediction of peptide retention times in high-pressure liquid chromatography on the basis of amino acid composition. AB - Analysis of peptides by reverse-phase high-pressure liquid chromatography would be simplified if retention times could be predicted by summing the contribution to retention of each of the peptide's amino acid side chains. This paper describes the derivation of values ("retention coefficients") that represent the contribution to retention of each of the common amino acids and end groups. Peptide retention times were determined on a Bio-Rad "ODS" column at room temperature with a linear gradient from 0.1 M NaclO(4), pH 7.4 or 2.1, at 0 min to 60% acetonitrile/0.1 M NaclO(4) at 80 min. The NaclO(4), a chaotropic agent, was added to improve peak shape and to minimize conformational effects. Retention coefficients for the amino acids were computed by using a Hewlett-Packard 9815A calculator programmed to change the retention coefficients for all amino acids sequentially to obtain a maximum correlation between actual and predicted retention times. Correlations of 0.999 at pH 7.4 and 0.997 at pH 2.1 were obtained for 25 peptides including glucagon, oxytocin, [Met]enkephalin, neurotensin, and somatostatin. This high degree of correlation suggests that, for peptides containing up to 20 residues, retention is primarily due to partition processes that involve all the residues. Although steric or conformational factors do have some effect on retention, the data suggest that under the above chromatographic conditions the retention of peptides containing up to 20 residues can be predicted solely on the basis of their amino acid composition. This possibility was tested by using data taken from the literature. PMID- 6929511 TI - Cotransfer of linked eukaryotic genes and efficient transfer of hypoxanthine phosphoribosyltransferase by DNA-mediated gene transfer. AB - The efficiency of DNA-mediated transfer of the gene (hprt) for hypoxanthine phosphoribosyltransferase (HPRT; IMP: pyrophosphate phosphoribosyltransferase, EC 2.4.2.8) is dependent upon the recipient cell used. hprt has been transferred into mouse TG8 or Chinese hamster CHTG49 cells at a high frequency, similar to the frequency of the gene (tk) for thymidine kinase (TK; ATP:thymidine 5' phosphotransferase, EC 2.7.1.21) transfer into mouse LMTK- cells (i.e., 10(-6)). In contrast, the frequency of transfer of hprt into mouse A9 cells was about two orders of magnitude less. The identification of efficient recipient cells for hprt transfer permits the use of DNA-mediated transfer as a bioassay for the gene. Cotransfer of the linked tk gene and the gene (galk) for galactokinase (ATP: D-galactose 1-phosphotransferase, EC 2.7.1.6) to LMTK- cells has been detected once among 87 tk transferrents. This suggests that the distance between the tk and galk genes in the Chinese hamster genome may be smaller than was previously thought. Significant differences between chromosome-mediated and DNA mediated gene transfer were observed with respect to both the size of the transferred functional genetic fragment and the recipient cell specificity. PMID- 6929514 TI - Choline accumulation by photoreceptor cells of the rabbit retina. AB - Photoreceptor cells of the rabbit retina accumulate choline from the extracellular environment by an overall process that has a high affinity for choline. These cells do not synthesize acetylcholine; instead, the choline taken up is incorporated into phosphorylcholine and eventually phospholipid. A mechanism for efficient choline accumulation is presumably concomitant to the photoreceptor cell's synthesis of large amounts of membrane for outer segment membrane renewal. Its existence in the photoreceptor cell supports previous evidence that high-affinity choline uptake is not confined to neurons that release acetylcholine, but may be present wherever large amounts of choline are required. PMID- 6929515 TI - Sodium and potassium salt stimulation of taste receptor cells: an allosteric model. AB - Stimulation of taste receptors with sodium chloride, sodium acetate, sodium propionate, and the respective potassium salts gave concentration-response profiles, measured electrophysiologically, which are remarkably consistent with a two-state allosteric mechanism. The allosteric constant or equilibrium constant for the transition between the active and inactive receptor states is low, resulting in a condition in which small differences in ion affinities for the two states are sufficient to significantly alter the equilibrium. Receptor activators, such as sodium ion, displaced the equilibrium toward the active receptor state by virtue of a higher affinity for that state, whereas receptor inhibitors, such as acetate and propionate ions, displaced the equilibrium in the opposite direction as a result of a higher affinity for the inactive state. The low allosteric constant increased about 10-fold after treatment with the protein modification reagent dimethyl(2-hydroxy-5-nitrobenzyl)sulfonium bromide, resulting in a marked reduction in the response to sodium chloride and sodium propionate without a significant change in ion affinities. In order to fully resolve the potassium response characteristics, it was necessary to consider both a potassium activation site and a potassium inhibition site. Analysis of the response from sodium chloride/potassium chloride mixtures showed that sodium ion is competitive with potassium binding at the activation site but not the inhibition site. With potassium propionate as the stimulus, the effect of both a receptor activator and a receptor inhibitor was quantitatively consistent with depression of the response below a water baseline level at low stimulus concentrations. Estimation of active and inactive state dissociation constants for each anion and cation permitted accurate prediction of the response magnitude for a range of cation ratios in sodium chloride/potassium chloride mixtures and anion ratios in sodium chloride/sodium propionate mixtures. The association of salty taste with receptor activators and bitter taste with receptor inhibitors may be relevant to the generation of these taste qualities. PMID- 6929516 TI - Physiological and morphological studies of rat pheochromocytoma cells (PC12) chemically fused and grown in culture. AB - Cell fusion induced by polyethylene glycol has been used to produce in culture giant multinucleate PC12 cells (up to 300 micron in diameter compared to 10-20 micron for unfused cells). Fused cells, like their unfused counterparts, were found to express various neuronal properties. They contained catecholamines. In the presence of nerve growth factor they extended long processes and expressed Na+, Ca2+, and K+ conductances generally associated with excitable cells. In the absence of nerve growth factor these cells neither grew long processes nor generated Na+-spikes. Other neuronal properties were also observed. PMID- 6929517 TI - Dissociation of vasoconstrictor and platelet aggregatory activities of thromboxane by carbocyclic thromboxane A2, a stable analog of thromboxane A2. AB - Carbocyclic thromboxane A2 [2 beta (Z),3 alpha- (1E,3R*)-3-(3-hydroxy(1-octenyl) bicyclo[3.1.1]hept-2-yl-5-heptenoic acid], a stable analog of thromboxane A2, has been tested for its physiologic properties. Carbocyclic thromboxane A2 is a potent coronary vasoconstrictor, stimulating cornonary vascular smooth muscle at concentrations as low as 29 pM. At 1-5 micro M it is also an inhibitor of arachidonic-acid- and endoperoxide-induced aggregation of platelets. At 200 nM it stimulated the release of lysosomal hydrolases from large granule fractions of liver homogenate. It inhibited thromboxane synthesis in platelets, although it did not inhibit synthesis of prostacyclin in ram seminal vesicles. Thus, carbocyclic thromboxane A2, a molecule closely related to thromboxane A2, separates coronary vasoconstrictor from platelet-aggregating activity. The constrictor activity predominates in vivo; carbocyclic thromboxane A2 induces coronary vasoconstriction leading to myocardial ischemia and sudden death in rabbits in the absence of pulmonary or coronary thrombosis. PMID- 6929518 TI - Chloride-activated passive potassium transport in human erythrocytes. AB - Passive K+ transport in human erythrocytes (defined as ouabain-insensitive transport) was inhibited 70% by replacement of Cl- by several permeant monovalent anions. The Vmax of Cl--dependent K+ influx was 1.14 mmol . liter-1, hr-1; its apparent Km for K+ was 4.7 mM. There was a much smaller component of Na+ influx dependent on Cl- (Vmax, 0.23 mmol . liter-1 . hr-1). Furosemide and other inhibitors of Cl- transport inhibited passive K+ transport to the same extent as replacement of Cl-, but 4-acetamido-4'-isothiocyanostilbene-2,2'-disulfonic acid, a specific inhibitor of anion exchange in erythrocytes, was ineffective. The Cl- dependent K+ transport, which may be K+/Cl- cotransport, could reflect a mechanism for regulating cell volume. PMID- 6929519 TI - Spontaneous cancer and its possible relationship to oxygen metabolism. AB - Mortality statistics for cancer in various countries and periods of time indicate that there has been little effect of industrialization on the inherent or spontaneous rate of occurrence of cancer. From U.S. cancer statistics and the BEIR values [Report of the Advisory Committee on the Biological Effects of Ionizing Radiation (1979)] for radiation dose response, the ionizing radiation exposure required to produce a number of cancers equal to this spontaneous incidence was estimated to lie between 450 and 2100 rads (1 rad = 0.01 J/kg). From these "cancer equivalent" doses the number of single-strand DNA breaks required to produce the spontaneous cancers is estimated to be 0.26-1.3 per cell DNA per day. It is suggested that the univalent reduction of oxygen in normal metabolism to O2- and subsequent production of more harmful radicals is the source of the DNA defects that, in cases where the defense mechanisms fail, lead to spontaneous cancer in the individual. PMID- 6929520 TI - Reconstitution of a deoxyribonuclease I-sensitive structure on active genes. AB - Chicken erythrocyte nuclei have been labeled in the active regions of the chromosome by using the nick translation reaction. In this procedure, accessible areas of the genome are preferentially nicked by the action of pancreatic DNase I and subsequently labeled by using DNA polymerase I from Escherichia coli. These nuclei were employed as a substrate for studying the factors responsible for maintaining the special chromatin conformation of the overall population of active genes. Treatment of nuclei with 0.35 M NaCl resulted in the loss of DNase I sensitivity in the active genes, but this sensitivity could be restored when nuclei were reconstituted with the NaCl eluate. Further purification of the released factors revealed that the HMG (high-mobility group) proteins HMG-14 and HMG-17 are involved in maintaining the conformation of the active regions. These factors are not tissue specific and seem to be involved in the chromosomal structure of most of the active genes. PMID- 6929521 TI - Regulation of protein synthesis during spore germination in Dictyostelium discoideum. AB - Spore germination in the slime mold Dictyostelium discoideum is a particularly suitable paradigm for studying the regulation of gene expression because developmentally regulated changes in both protein and mRNA synthesis occur during the synchronous transition from dormant spore to growing ameba. To investigate the regulation of protein synthesis during germination, we labeled activated spores with [35S]methionine at 1-hr intervals during germination, until amebas emerged (at 3 hr). The labeled proteins were resolved by two-dimensional polyacrylamide gel electrophoresis. Six classes of proteins were distinguished, depending on the time of onset and duration of their synthesis: (i) proteins made only during the first hour of germination, (ii) proteins made during the second hour, (iii) proteins made during the third hour, (iv) those synthesized only between 1 and 3 hr after activation, (v) peptides made only between 0 and 2 hr after activation, and (vi) proteins that were made throughout germination, mRNA isolated from dormant spores and from spores at different stages of germination was translated in a wheat germ cell-free protein-synthesizing system, and the proteins made in vitro were compared to those synthesized in vivo. The majority of the changes in the pattern of protein synthesis that occurred during the different stages of germination were attributable to the presence or absence of translatable mRNA. It is concluded that the synthesis of a majority of the proteins during spore germination is transcriptionally controlled. PMID- 6929523 TI - Different half-lives of the carbohydrate and protein moieties of a 110,000-dalton glycoprotein isolated from plasma membranes of rat liver. AB - By using a four-step procedure (i, solubilization with Triton X-100; ii, affinity chromatography on concanavalin A-Sepharose; iii, affinity chromatography on wheat germ lectin-Sepharose; iv, preparative sodium dodecyl sulfate gel electrophoresis) a glycoprotein was isolated from rat liver plasma membrane. The molecular weight is 110,000 and the isoelectric point is 5.8. It contains L fucose, N-acetylneuraminic acid, D-galactose, D-mannose, N-acetyl-D-glucosamine, N-acetyl-D-galactosamine, and considerable quantities of aspartate, threonine, serine, and leucine. In pulse-chase experiments the half-lives of methionine and arginine, representing the half-life of the protein, were determined as 70 hr and 78 hr, respectively. The half-lives of the terminal carbohydrates L-fucose and N acetylneuraminic acid were 12.5 and 33 hr, respectively. The galactose half-life was 20 hr. From this it is concluded that terminal sugars turn over several times in the life-span of this protein molecule. This process may be operative during membrane recycling mechanisms. PMID- 6929522 TI - Deoxyribonucleotide pools, base pairing, and sequence configuration affecting bromodeoxyuridine- and 2-aminopurine-induced mutagenesis. AB - Despite recent experiments showing that BrdUrd-induced mutagenesis can be independent of the level of bromouracil (BrUra) substitution [Kaufman, E.R. & Davidson, R.L. (1978) Proc. Natl. Acad. Sci. USA 75, 4982-4986; Aebersold, P.M. (1976) Mutat. Res. 36, 357-362], BrUra.G base mispairs are a major determinant of mutagenesis. We propose that the experiments cited above are sensitive predominantly to G . C leads to A . T transitions driven by the immeasurably small but highly mutagenic substitution of BrUra for cytosine and not by the gross substitution of BrUra for thymine in DNA. More generally, we show how accumulated evidence suggests that both BrdUrd and 2-aminopurine have two mutagenic effects intracellularly: perturbation of normal deoxyribonucleoside triphosphate pools and analogue mispairs in DNA. We propose a molecular basis for various observations of normal exogenous deoxyribonucleosides as synergists and counteragents to base analogue mutagenesis. A model is proposed to explain the antipolarity of BrdUrd and 2-aminopurine mutagenesis--i.e., why mutants at hot spots for induction by one base analogue are usually hot spots for reversion by the other. It is concluded that the configuration of the neighboring nucleotides surrounding the base analogue mispair, and not the base analogue's preference for inducing A . T leads to G . C or G . C leads to A . T errors, is responsible for the antipolarity of BrdUrd and 2-aminopurine mutagenesis. PMID- 6929525 TI - Repeating structure of cytoplasmic poly(A)-ribonucleoprotein. AB - A repeating structure of cytoplasmic poly(A)-ribonucleoprotein is revealed by digestion with T2 RNase. A pattern of fragments that are multiples of about 27 residues is obtained. The repeating structure is readily reconstituted from purified poly(A) and cytoplasmic factors. Reconstitution is specific for poly(A), as shown by the lack of competition by poly(G), poly(C), poly(dA), and tRNA. The repeating structure is absent from the nucleus, and so appears to be formed upon transport to the cytoplasm. PMID- 6929524 TI - X-ray-structure of a cytidylyl-3',5'-adenosine-proflavine complex: a self-paired parallel-chain double helical dimer with an intercalated acridine dye. AB - The non-self-complementary dinucleoside monophosphate cytidylyl-3',5'-adenosine (CpA) forms a base-paired parallel-chain dimer with an intercalated proflavine. The dimer complex possesses a right-handed helical twist. The dimer helix has an irregular girth with a neutral adenine-adenine (A-A) pair, hydrogen-bonded through the N6 and N7 sites (C1'...C1' separation of 10.97 A), and a triply hydrogen-bonded protonated cytosine-cytosine (C-C) pair with a proton shared between the base N3 sites (Cl'...Cl' separation of 9.59 A). The torsion angles of the sugar-phosphate backbone are within their most preferred ranges and the sugar puckering sequence (5' leads to 3') is C3'-endo, C2'-endo. There is also a second proflavine molecule sandwiched between CpA dimers on the 21-axis. Both proflavines are necessarily disordered, being on dyad axis, and this suggests possible insights into the dynamics of intercalation of planar drugs. This structure shows that intercalation of planar drugs in nucleic acids may not be restricted to antiparallel complementary Watson-Crick pairing regions and provides additional mechanisms for acridine mutagenesis. PMID- 6929526 TI - Regulation of early adenovirus transcription: a protein product of early region 2 specifically represses region 4 transcription. AB - An aspect of the regulation of early adenovirus gene expression has been studied by measuring the rates of transcription of several viral transcription units during infection by wild-type (WT) adenovirus type 5 and a temperature-sensitive mutant, H5ts125. It has previously been shown that two transcription units (regions 2 and 4) are subject to negative control. During the course of early infection, transcription of regions 2 and 4 increased to a maximal rate and then declined. The decline from each of these transcription units appeared to be a specific shutoff of transcription, because the transcription of another early transcription unit (region 1A) remained constant during early infection and, in the absence of protein synthesis, the apparent shutoff of region 2 and region 4 transcription did not occur. At the nonpermissive temperature for the mutant, the kinetics of transcription of early region 2 were identical to the kinetics of transcription of WT. Thus, the repression of transcription of region 2 occurred in H5ts125-infected cells as well as in WT-infected cells. Region 4 transcription, however, was not repressed during H5ts125 infection at the nonpermissive temperature. After a maximal rate of transcription was reached, this rate was maintained throughout the course of the experiment. Furthermore, the repression of region 4 transcription appears to be the result of a block of initiation of transcription rather than the result of an inducement of premature termination of transcription. Therefore, it can be concluded that a product of the adenovirus region 2 gene, which is the site of the mutation for H5ts125, is responsible for the specific shutoff of region 4 transcription. PMID- 6929527 TI - Limited DNase I nicking as a probe of gene conformation. AB - We have extended the use of pancreatic DNase I as a probe of chromatin structure by exploring the accessibility of an active gene to the introduction of the first single-stranded nick. We show by a target analysis that the beta-globin gene is about 25-fold more sensitive to single-site nicking than is an average sequence in the chicken erythrocyte nucleus or the nontranscribed albumin gene. The sites of initial DNase I nicking are shown to cluster within the transcribed sequence of the beta-globin gene. PMID- 6929528 TI - Multiple forms of H4 histone mRNA in human cells. AB - Two species of H4 histone mRNA were isolated from the polysomes of S phase HeLa S3 cells. Electrophoresis under denaturing and nondenaturing conditions indicates that the two H4 mRNAs differ in size. Both mRNAs translate H4 histones in vitro, lack poly(A) at their 3' termini, and are capped at their 5' termini. Polyacrylamide gel electrophoresis and tryptic peptide analysis suggest that the polypeptides synthesized by the two mRNAs are indistinguishable. PMID- 6929531 TI - Photodestruction of acetylcholinesterase. AB - Ultraviolet irradiation of 11S acetylcholinesterase (acetylcholine acetylhydrolase, EC 3.1.1.7) produces a loss of tryptophan fluorescence which is best described as the sum of two separable first-order processes, one much more rapid than the other. In addition, the enzyme undergoes an all-or-none inactivation that is monotonically first order. Simultaneous with activity loss, photoscission takes place and results in a molecular weight drop of 1 x 10(5); this decrease is first order with a rate constant identical to that for enzymatic inactivation. These processes are accompanied by apparent conformational changes, as shown by circular dichroic and difference absorption spectra. The relative photochemical inactivation efficiency of incident light is unity when corrected for the wavelength dependence of fluorescence excitation, which is consistent with an efficient Forster resonance transfer of energy among the aromatic chromophores. The extreme sensitivity of acetylcholinesterase to photodestruction upon photon absorption and the several events that follow it not only suggest that these findings might be a basis for a useful molecular probe of the structure of this enzyme, but also indicate that additional care should be taken when conducting spectroscopic studies in the UV region. PMID- 6929530 TI - Rate enhancement of reconstitution of glyceraldehyde-3-phosphate dehydrogenase by a covalently bound coenzyme analog. AB - Kinetic analysis of the in vitro reconstitution of glyceraldehyde-3-phosphate dehydrogenase [D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating), EC 1.2.1.12] from yeast showed that both oxidized and reduced coenzyme enhance the transconformation reaction, which is rate limiting in the sequential folding-association process at high enzyme concentrations (Krebs, H., Rudolph, R. & Jaenicke, R. (1979) Eur. J. Biochem. 100, 359-364). In the present study the reconstitution of the enzyme has been analyzed after covalent modification with the coenzyme analog 3-[(3-bromoacetylpyridinio) propyl]adenosine pyrophosphate. Reconstitution of the modified enzyme, as determined by the regain of the native tryptophan fluorescence, is found to be more then 10 times faster than refolding of the unmodified apoenzyme and more than 5 times faster than that of the unmodified holoenzyme. Various degrees of denaturation and the presence of up to 0.4 M guanidine . HCl do not affect the rate of reconstitution of the modified enzyme. The kinetic effect of free or covalently bound coenzyme is discussed in terms of a decrease in free energy of the native or native-like structure or in terms of a decreased activation energy of rate-limiting steps in the process of reconstitution. Stabilization of the dimeric intermediate or acceleration of its transformation seems to be the most likely explanation for the observed effect of free or covalently bound coenzyme on the rate of reconstitution. PMID- 6929529 TI - Methotrexate-induced misincorporation of uracil into DNA. AB - A line of human lymphoid cells was tested for the presence of dUMP in DNA with or without treatment with the dihydrofolate reductase inhibitor, methotrexate. Cells treated with methotrexate and labeled with [(3)H]dUrd contained dUMP in DNA in readily detectable amounts ( approximately 0.8 pmol of dUMP per mumol of total DNA nucleotide), and this was increased approximately 3-fold if the cells were also treated with Ura at the same time. No dUMP (<1 fmol/mumol of DNA) could be detected by these methods in DNA from cells not treated with methotrexate, regardless of whether Ura was present or absent. The presence of dUMP in DNA from cells treated with methotrexate is a result of the great increase in intracellular concentration of dUTP and the fall in dTTP that accompany inhibition of thymidylate synthetase (5,10-methylenetetrahydrofolate:dUMP C methyltransferase; EC 2.1.1.45) by the drug. These changes are apparently sufficient to overcome the normal mechanisms that exclude dUMP from DNA, and the enhancement by Ura reflects suppression of one of the mechanisms, Ura removal from DNA by the enzyme Ura-DNA glycosylase. The results suggest an active lesion of DNA in cells in which thymidylate synthetase is inhibited. Under these conditions there appears to be a cyclic incorporation and removal of dUMP resulting from reinsertion of dUMP during gap repair at sites of Ura removal. This consequence of the normal excision-repair process, which occurs when intracellular levels of dUTP approach those of dTTP, may have effects related to the cytotoxicity of drug inhibitors of thymidylate synthetase, clinical deficiencies of folate and vitamin B-12, and thymineless death, in general. PMID- 6929532 TI - Effect of introduction of small alkyl groups on mRNA function. AB - Treatment of RNA with dimethyl sulfate methylates only nitrogens, preferentially the 7 position of guanosine, whereas treatment with ethylnitrosourea ethylates mainly oxygens, preferentially the phosphodiester groups. Two plant viral mRNAs were modified with these two reagents at levels of 4-28 alkylations per molecule. The ability of alkylated RNAs to stimulate amino acid incorporation in the wheat germ system was somewhat diminished by both types of modification, but the predominant protein made, as ascertained by polyacrylamide gel electrophoresis, was the typical gene product of the respective mRNA. These data suggest that random alkylations, mostly of either the guanosine N-7s or the phosphates, do not interfere with peptide chain elongation, but that the ability to initiate translation properly is affected by these substitutions, presumably through their effect on the conformation of the RNAs. PMID- 6929533 TI - Binding of diphtheria toxin to phospholipids in liposomes. AB - Diphtheria toxin bound to the phosphate portion of some, but not all, phospholipids in liposomes. Liposomes consisting of dimyristoyl phosphatidylcholine and cholesterol did not bind toxin. Addition of 20 mol% (compared to dimyristoyl phosphatidylcholine) of dipalmitoyl phosphatidic acid, dicetyl phosphate, phosphatidylinositol phosphate, cardiolipin, or phosphatidylserine in the liposomes resulted in substantial binding of toxin. Inclusion of phosphatidylinositol in dimyristol phosphatidylcholine/cholesterol liposomes did not result in toxin binding. The calcium salt of dipalmitoyl phosphatidic acid was more effective than the sodium salt, and the highest level of binding occurred with liposomes consisting only of dipalmitoyl phosphatidic acid (calcium salt) and cholesterol. Binding of toxin to liposomes was dependent on pH, and the pattern of pH dependence varied with liposomes having different compositions. Incubation of diphtheria toxin with liposomes containing dicetyl phosphate resulted in maximal binding at pH 3.6, whereas binding to liposomes containing phosphatidylinositol phosphate was maximal above pH 7. Toxin did not bind to liposomes containing 20 mol% of a free fatty acid (palmitic acid) or a sulfated lipid (3-sulfogalactosylceramide). Toxin binding to dicetyl phosphate or phosphatidylinositol phosphate was inhibited by UTP, ATP, phosphocholine, or p nitrophenyl phosphate, but not by uracil. We conclude that (a) diphtheria toxin binds specifically to the phosphate portion of certain phospholipids, (b) binding to phospholipids in liposomes is dependent on pH, but is not due only to electrostatic interaction, and (c) binding may be strongly influenced by the composition of adjacent phospholipids that do not bind toxin. We propose that a minor membrane phospholipid (such as phosphatidylinositol phosphate or phosphatidic acid), or that some other phosphorylated membrane molecule (such as a phosphoprotein) may be important in the initial binding of diphtheria toxin to cells. PMID- 6929534 TI - Identification of a region susceptible to proteolysis in myosin subfragment-2. AB - Comparison of the NH2-terminal sequence of myosin short subfragment-2 (Mr of subunit = 37,000) and long subfragment-2 (Mr of subunit = 59,000) demonstrates that the former represents the NH2-terminal portion of the latter and suggests that the hinge region in myosin rod is in the COOH-terminal portion of the long subfragment-2. PMID- 6929535 TI - Path of the polypeptide in bacteriorhodopsin. AB - An attempt has been made to fit the amino acid sequence of bacteriorhodopsin to the three-dimensional density map of the molecule. First, seven segments of the sequence were selected as being probable transmembrane alpha helices. Then each of the 5040 possible ways of fitting these seven segments into the seven regions of helical density in the map were evaluated based on the criteria of connectivity of the nonhelical link regions, charge neutralization, and total scattering density per helix. A single model that may be experimentally tested emerged as the most probable. PMID- 6929536 TI - Differences in Fe(II)-N epsilon(His-F8) stretching frequencies between deoxyhemoglobins in the two alternative quaternary structures. AB - Resonance Raman spectra have been obtained of the alpha deoxy and beta deoxy subunits within valency hybrid hemoglobins both in the high-affinity (R) and low affinity (T) structures. Upon conversion from the R to the T structure, the vibrational frequency of the Fe(II)-N epsilon(His-F8) bond changes from 223 to 207 or 203 cm-1 in the alpha deoxy subunit and from 224 to 220 or 217 cm-1 in the beta deoxy subunit. We estimate that the Fe(II)-N epsilon(His-F8) bond is stretched by the R leads to T transition 3 times more in the alpha subunit (0.024 A) than in the beta subunit (0.0085 A) and, accordingly, the strain energy developed in that bond is 8 times larger in the alpha than in the beta subunit. Hence, the oxygen affinity of the alpha and beta subunits may be regulated by different mechanisms. PMID- 6929537 TI - Effect of bleaching light on measurements of lateral diffusion in cell membranes by the fluorescence photobleaching recovery method. AB - The Fc receptors for IgE on rat basophil leukemia 2H3 cells were labeled with either rhodamine- or fluorescein-conjugated IgE and then with Fab fragments of anti-IgE conjugated with the other dye. Fluorescence photobleaching recovery measurements of lateral diffusion were performed with one of the dyes before and after extensive bleaching of the other dye over an entire cell. Bleaching one dye did not affect subsequent measurements made with the other dye. We thus detect no evidence for photoinduced artifacts in fluorescence photobleaching recovery experiments. PMID- 6929538 TI - Kinetics of erythroid precursors in mice infected with the anemic or the polycythemic strain of Friend leukemia virus. AB - The kinetics of both erythroid burst-forming and colony-forming units (BFU-E, CFU E) and myelomonocytic precursors [myelomacrophage colony-forming unit (CFU-C)] have been evaluated in tibial marrow, peripheral blood, and spleen of DBA/2 mice at time intervals after inoculation of either the anemic (FLV-A) or the polycythemic (FLV-P) strain of Friend leukemia virus. Either one of the viruses induced, at 7-10 days after infection, a massive increase in the number of BFU-Es in peripheral blood, in parallel with their depletion in tibial marrow and increase in spleen. A comparable increase in the blood BFU-E number was observed in splenectomized FLV-infected mice. These results indicate a marrow-spleen migration of BFU-Es. In spleen, the increase of the BFU-E number was associated with an increase in the CFU-E pool. In tibial marrow, a sequence of expansion/depletion waves occurred reciprocally at the level of BFU-E and CFU-E. The cycling of BFU-E([(3)H]thymidine in vitro suicide index) in marrow, blood, and spleen was enhanced, whereas that of CFU-E and CFU-C showed little or no modification. These kinetic data suggest that the main target cell of FLV may be the BFU-E or a closely related element. In plates without added erythropoietin (but containing it in fetal calf serum), expression of CFU-E from FLV-P-treated animals was maximal; that of CFU-E from FLV-A-injected mice was either virtually absent or only slight in marrow or spleen, respectively. BFU-E growth always was fully dependent upon erythropoietin addition. Control studies in FLV-infected resistant mice and in susceptible mice given diluted or heat-inactivated virus provide convincing evidence that the phenomena described are induced by FLV. PMID- 6929539 TI - Use of collagen-hydroxyethylmethacrylate hydrogels for cell growth. AB - Collagen-hydroxyethylmethacrylate hydrogels were prepared by polymerizing monomeric hydroxyethylmethacrylate in the presence of various concentrations of soluble native collagen. The resulting transparent hydrogels were evaluated as substrata for growth of IMR-90 human embryonic lung fibroblasts. Without collagen no significant growth occurred, whereas a dose-response curve expressing maximal cell growth against collagen concentration could be constructed quite readily by the use of appropriate hydrogels. The method allows for quantification of the collagen contribution to cell growth and, in a more general sense, provides the foundation for a relatively easy procedure to probe mechanisms of cell adhesion and cell differentiation. PMID- 6929542 TI - Cytogenetic effects of inhaled benzene in murine bone marrow: induction of sister chromatid exchanges, chromosomal aberrations, and cellular proliferation inhibition in DBA/2 mice. AB - Exposure of adult male and female DBA/2 mice to 3100 ppm benzene for 4 hr significantly increased the frequency of sister chromatid exchanges in bone marrow cells of both sexes, inhibited marrow cellular proliferation (but only in male mice), and did not significantly increase the frequency of chromosomal aberrations in either sex. Phenobarbital pretreatment synergistically interacted with benzene exposure to further increase sister chromatid exchanges in female mice, induce greater inhibition of cellular proliferation in male mice, and induce a significant level of chromatid-type chromosomal aberrations in both sexes. During the second day after exposure to benzene there was increased inhibition of cellular proliferation in male mice and both new DNA damage and persistance of old DNA damage in female mice. The differences in both the type and magnitude of the response of bone marrow cellular populations, as determined by different cytogenetic end points in male and female DBA/2 mice exposed to benzene or to phenobarbital and benzene, suggest not only that a metabolite of benzene is responsible for the observed effects, but that different metabolites may be involved in different end points. PMID- 6929540 TI - Sustained growth in primary culture of normal mammary epithelial cells embedded in collagen gels. AB - Normal mammary epithelial cells from BALB/cfC3H midpregnant mice were freed from stromal cell types by Percoll density gradient centrifugation after collagenase digestion and were then embedded within collagen gels. Sustained growth leading to an increase in cell number was accomplished in response to cholera toxin and high concentrations of horse serum. The extent of growth was found to be dependent on the horse serum concentration, the maximum growth being attained at 50%. A serum concentration of 12.5% horse serum and 2.5% fetal calf serum, along with cholera toxin at 0.01 mug/ml, allowed maintenance but failed to cause any significant increase in cell number during the experimental period of 2 weeks. This same maintenance medium was used to determine the effects of various exogenously added steroids, protein hormones, and organ extracts on the proliferation of mammary epithelial cells in culture. Hormones failed to elicit any proliferative response, but extracts of kidney, brain, uterus, and spleen produced proliferative responses equal to or greater than the response obtained with 50% horse serum and cholera toxin. Kidney extracts prepared from midpregnant mice, virgin mice, and virgin mice given pituitary isografts all showed comparable activities, suggesting that the concentration of stimulatory factor(s) was not influenced by the hormonal status of the donor. Normal mammary epithelial cells that had undergone a 10- to 15-fold increase in cell number over initial values during 2-3 weeks in culture were passaged to secondary gel cultures. Outgrowth similar to those seen in primary culture were seen again in secondary culture. The present system provides a method for sustaining growth in culture of primary mammary epithelial cells from normal tissues. PMID- 6929541 TI - Control of membrane permeability by external and internal ATP in 3T6 cells grown in serum-free medium. AB - Cultures of 3T6 cells were plated in serum-free medium and grown in the presence of insulin (1 microgram/ml) and epidermal growth factor (0.5 ng/ml). External ATP (250 microM) applied to such cultures caused a rapid efflux of acid-soluble pools labeled with [3H]uridine, 2-deoxy[3H]glucose, or 86Rb+ and allowed the entry of p nitrophenylphosphate. This increase in passive membrane permeability depended on ATP concentration, pH, and time of ATP contact with the cells, and it was not produced by GTP, UTP, or Pi. In the presence of compounds that decrease intracellular ATP, low concentrations of external ATP (40 microM) caused a massive synergistic stimulation of efflux. The efflux of acid-soluble pools was stopped (sealing) by bringing the cultures of 3T6 cells to neutral pH in the presence of Ca2+ and Mg2+. Exposure of 3T6 cells grown in serum-free medium to [gamma-32P]ATP under the conditions of permeabilization led to the selective labeling of a membrane protein with a molecular weight of 44,000 as revealed by NaDodSO4 polyacrylamide gel electrophoresis and autoradiography. The results show that the control of membrane permeability by ATP is completely independent of serum-deprived proteins. Furthermore, the protein band (Mr, 44 x 10(3)) that shows selective labeling by [32P]ATP during permeabilization is not an adsorbed serum component. PMID- 6929543 TI - Rapid duplication and loss of genes coding for the alpha chains of hemoglobin. AB - Rapid cycles of gene duplication and loss appear to have been going on in the region coding for the alpha chain of adult hemoglobin. This is inferred from restriction endonuclease analysis of the alpha gene region in five species of apes, whose common ancestor lived about 10 million years ago. Because all five species resemble humans in having duplicate alpha genes, the duplicate state of this region is probably at least as old as the common ancestor of all these species. However, the alpha polypeptides within these species are about 10 times more alike than is expected for 10 million years of divergent evolution. Thus, the alpha polypeptides within each species have been evolving in concert. Changes in gene number have also taken place in the apes. Whereas the predominant number of alpha genes per chromosome is two for most species, it is three for chimpanzees. Concerted evolution appears also to have occurred, but far more slowly, in the region coding for the adult beta-like chains of hemoglobin. Consideration of the structural differences between the two regions leads to the hypothesis that the lengths of the noncoding regions are important determinants of the rates at which genes are gained and lost by intergenic recombination. PMID- 6929544 TI - Identification of a cell surface protein, p97, in human melanomas and certain other neoplasms. AB - BALB/c mice were immunized with a human melanoma cell line, SK-MEL 28, and their spleen cells were fused with mouse NS-1 myeloma cells. Hybrid cells were tested in an indirect 125I-labeled protein A assay for production of antibodies that bound to surface antigens of SK-MEL 28 melanoma cells but not to autologous skin fibroblasts. One hybridoma, designated 4.1, had the required specificity. It was cloned and grown in mice as an ascites tumor. The monoclonal IgG1 antibody produced by the hybridoma was purified from the ascites fluid and labeled with 125I. The labeled antibody bound, at significant levels, to approximately 90% of the melanomas tested and to approximately 55% of other tumor cells, but not to three B-lymphoblastoid cell lines or to cultivated fibroblasts from 15 donors. Immunoprecipitation and sodium dodecyl sulfate gel electrophoresis were used to detect the target antigen in 125I-labeled cell membranes of both cultivated cells and tumor biopsy samples. A protein with a molecular weight of 97,000 was identified. This protein, designated p97, was present in both cultured cells and biopsy material from melanomas and certain other tumors, but it was not detected in eight different samples of normal adult epithelial or mesenchymal tissues obtained from five donors. PMID- 6929545 TI - Plasma membrane polypeptides of resident and activated mouse peritoneal macrophages. AB - With the lactoperoxidase/glucose oxidase-catalyzed iodination method, we have identified at least 19 exteriorly disposed plasma membrane polypeptides on mouse peritoneal macrophages, with molecular weights ranging from 12,000 to 290,000. Resident and inflammatory macrophages could be distinguished by qualitative and quantitative differences in the display of selected polypeptides, although the overall banding patterns were similar. Some of the labeled polypeptides were identified by immunoprecipitation. PMID- 6929546 TI - Membrane potential changes during mitogenic stimulation of mouse spleen lymphocytes. AB - By monitoring differences in accumulation of the lipophilic cation [(3)H]tetraphenylphosphonium in media containing low or high potassium concentrations [Lichtshtein, D., Kaback, H. R. & Blume, A. J. (1979) Proc. Natl. Acad. Sci. USA 76, 650-654], the membrane potential of lymphocytes from various sources has been estimated. On the basis of this method, the potential of normal mouse spleen lymphocytes (T and B cells) is -65 +/- 2 mV (mean +/- SEM, interior negative). During the course of mitogenic stimulation by concanavalin A, lipopolysaccharide, or fetal calf serum, the membrane potential of murine spleen lymphocytes changes systematically according to the following pattern: (i) early depolarization lasting 2-3 hr, (ii) repolarization over the next 7 hr, and (iii) a final hyperpolarization phase during the last 24-48 hr. During repolarization and hyperpolarization, moreover, there is a direct correlation between the membrane potential and DNA synthesis, as judged by [(3)H]thymidine incorporation. By using isolated T and B cells, it is observed that concanavalin A depolarizes T cells only, whereas lipopolysaccharide depolarizes B cells only. Thus, both mitogens exhibit the same specificity for depolarization as for mitogenic stimulation. On the basis of these observations, it is suggested that the transition of lymphocytes from a resting state to mitotic activity is initiated by depolarization of the plasma membrane. PMID- 6929548 TI - Unreliability of tritiated cholesterol: studies with [1,2-3H]-cholesterol and [24,25-3H]cholesterol in humans. AB - Over the past 18 months different lots of [1,2-3H]cholesterol and [24,25 3H]cholesterol were found to be radiochemically acceptable by conventional chemical and other in vitro tests, yet, when co-administered with [4 14C]cholesterol to human subjects, an abrupt fall in the 3H/14C specific activity ratio in plasma cholesterol was discovered in every case. We have concluded that all batches of [3H]cholesterol should be regarded as radiochemically unreliable unless they are shown to behave identically in all respects to [4-14C]cholesterol in an appropriate in vivo assay system. PMID- 6929547 TI - Phalloidin-induced cholestasis: a microfilament-mediated change in junctional complex permeability. AB - Phalloidin, administered to male rats for 7 days (500 microgram per kg/day), increased the mean hepatic content of filamentous actin. Both bile flow and bile acid excretion diminished proportionally, whereas the bile-to-plasma ratios of [3H]inulin and [14C]sucrose increased significantly from 0.08 and 0.16 in controls to 0.37 and 0.69, respectively, in phalloidin-treated animals. Simultaneously, junctional permeability was altered as noted by the free penetration of ionic lanthanum into the zonula occludens and bile canaliculus. Freeze-fracture replicas of the junctional complex revealed rearrangements of the junctional elements and regions in which only a single element separated the canaliculus from the lateral intercellular space. These findings suggest that microfilaments influence the permeability of "tight junctions" between hepatocytes and that bile constituents might reflux from the canaliculus to the intercellular space in phalloidin-induced cholestasis. PMID- 6929549 TI - Crystalline ribosomes are present in brains from senile humans. AB - Paracrystalline inclusions known as Hirano bodies characteristically appear in the hippocampal region of the brains of humans exhibiting senile and presenile dementias as well as several other neurodegenerative diseases. We present evidence that the currently accepted model for those structures based on alternating filament sheets is not correct, but that Hirano bodies are stacked sheets of membrane-bound ribosomal particles derived from partially degraded rough endoplasmic reticulum or Nissl substance. Using fluorescence staining with acridine orange and ethidium bromide, were have shown that the bodies contain RNA. Spatial filtering of electron micrographs by Fourier techniques shows that the individual particles that make up the arrays have a characteristic shape previously reported for the large subunit of eukaryotic ribosomes. The storage of these ribosomal particles in inclusion bodies may indicate a quiescent state of protein synthesis in the cells. This withdrawal of synthetic mechanisms in the hippocampus may have significant consequences in the loss of ability to consolidate short-term to long-term memory. PMID- 6929551 TI - Right and left eye bands in frogs with unilateral tectal ablations. AB - Surgical ablation of a single tectal lobe in Rana pipiens can cause regenerating retinal ganglion cell axons to cross to the remaining tectum. These synaptically deprived fibers can obtain termination space in a retinotopic and highly stereotyped manner. Each of the two eyes can share the undisturbed tectum by terminating in mutually exclusive, eye-specific stripes that alternate across the medial-lateral extent of the tectal lobe. Invading axons from the ipsilateral eye must actively displace established synapses from the contralateral eye in order to form these exclusive termination zones because the normal projection to the intact tectum is not severed in these experiments. In animals in which a large proportion of anomalous fibers do not reach the undisturbed tectum, only a few ipsilateral eye bands are observed. Nevertheless, these bands have the same width, periodicity, and orientation as those observed in fully banded preparations. When ipsilateral eye terminal density is extremely low, banding is absent. The completely striped termination pattern of unitectal animals is identical to the pattern previously reported in the dually innervated tecta of three-eyed R. pipiens. We theorize that this pattern results from a compromise between two synaptogenic forces that are active in regeneration as well as in development. PMID- 6929552 TI - Circadian rhythms of melatonin release from individual superfused chicken pineal glands in vitro. AB - The pineal gland of birds contains one or more circadian oscillators that play a major role in overall temporal organization. We have developed a flow-through culture system for the isolated pineal by which we can measure the release of melatonin continuously from superfused glands over long periods of time. Chicken pineals release melatonin rhythmically, and these rhythms persist in vitro with a circadian oscillation. In light cycles the release of melatonin is strongly rhythmic; however, in constant conditions the amplitude of the rhythm is lower and appears to be damping. Light has at least two effects upon the isolated pineal: cyclic light input synchronizes the rhythm, and acute light exposure at night rapidly inhibits melatonin release. The cultured avian pineal clearly offers great potential as a model system for the study of vertebrate circadian oscillators and may open the way for an analysis of mechanism. PMID- 6929550 TI - Denervation increases turnover rate of junctional acetylcholine receptors. AB - The turnover rates of junctional acetylcholine receptors were measured in innervated and denervated mouse sternomastoid neuromuscular junctions by 125I labeled alpha-bungarotoxin binding. First, we determined that the density of labeled toxin initially bound to the neuromuscular junction was essentially unchanged up to 16 days after denervation. Innervated muscles and muscles that had been denervated 8 days previously were then saturated with labeled toxin, and the specific label at the endplate regions was compared by gamma counting 7 days later. At that time, the residual junctional label seen in innervated muscle was 3.2 times greater than in denervated muscle. Electron microscope autoradiography further showed that, after saturation with unlabeled toxin, new binding sites appeared rapidly at the specialized receptive region of the postsynaptic membrane with an apparent half-time of turnover of 2-3 days. At innervated junctions, the half-time of turnover was about 10 days. These data show that the mechanisms that control receptor turnover rates are different from those that control high density receptor clustering. The slow turnover rate of junctional receptors appears to be more directly dependent on the presence of the nerve than is the clustering of junctional receptors. PMID- 6929553 TI - Locomotor activation induced by infusion of endorphins into the ventral tegmental area: evidence for opiate-dopamine interactions. AB - beta-Endorphin in nanomole quantities produced a stimulation of locomotor activity when infused into the region of the dopamine cell bodies of the ventral tegmental area (VTA) in rats. alpha-, gamma-, and des-Tyr-gamma-endorphin produced similar effects, but the D-alanine analogues of alpha and gamma endorphin produced a larger and longer-lasting activation, presumably reflecting their resistance to degradation. This locomotor activation was reversible by pretreatment with naloxone and by destruction of the terminal projections of the mesocorticolimbic dopamine system originating in the VTA. These results demonstrate that locally infused endorphin can interact with the opioid receptors in the VTA, and they suggest a means by which endorphins activate limbic excitability. PMID- 6929554 TI - Purification and primary structure of two neuroactive peptides that cause bag cell afterdischarge and egg-laying in Aplysia. AB - Two neuroactive peptides, A and B, have been isolated from the atrial gland in the reproductive tract of Aplysia. Each of the two peptides is able to induce egg laying behavior in recipient animals. In vitro recordings from the abdominal ganglion show that both peptides also trigger longlasting discharges in the bag cell neurons at concentrations around 0.1 muM. The peptides were purified by a combination of ammonium sulfate precipitation, agarose gel filtration, and cation exchange chromatography. Each peptide has 34 amino acid residues. Microsequencing together with carboxypeptidase Y degradation and analysis of tryptic peptides revealed the following sequence for peptide A: H-Ala-Val-Lys-Leu-Ser-Ser-Asp-Gly Asn-Tyr-Pro-Phe-Asp-Leu-Ser-Lys-Glu-Asp-Gly -Ala-Gln-Pro-Tyr-Phe-Met-Thr-Pro-Arg Leu-Arg-Phe-Tyr-Pro-Ile. Peptide B differs from A in only four positions. The first nine residues of B are: Ala-Val-Lys-Ser-Ser-Ser-Tyr-Glu-Lys-, whereas residues 10-34 of B are identical to those of A. The calculated M(r) of A is 3924 and that of B is 4032. The pI of peptide A as determined by isoelectric focusing in polyacrylamide gels is 7.9-8.1 and that of peptide B is 9.0-9.2. It is estimated that each atrial gland contains at least 150 mug of peptide A and 50 mug of B. Neither peptide resembles the egg-laying hormone isolated from bag cell neurons. It is postulated that the atrial gland peptides are released during copulation, and then by interacting with neuronal receptors in the head ganglia and pleuroabdominal connectives they cause the bag cells to afterdischarge, thereby releasing egg-laying hormone. PMID- 6929556 TI - [Sideroblastic anemia and myelomonocytic leukosis]. PMID- 6929557 TI - [Immunotherapy of cancer: evolution of concepts and clinical advances]. PMID- 6929555 TI - Effect of a specific 5HT uptake inhibitor (citalopram) on drug accumulation by rat lung slices. AB - Rat lung slices were used to examine the effects of citalopram, a compound reported to be a specific inhibitor of neuronal uptake of 5-hydroxytryptamine (5HT), on the pulmonary accumulation of 5HT, noradrenaline (NA), imipramine (IP) and paraquat (PQ). 5 X 10(-9) mol/l citalopram inhibited 5HT uptake by 30-40% but NA uptake was not affected at any of the concentrations of citalopram studied. At the highest concentrations of citalopram (10(-5) to 10(-4) mol/l) the accumulation of IP and PQ was reduced by25-30%. It is concluded that at low concentrations, citalopram is a specific and potent inhibitor of 5HT uptake by rat lung slices. PMID- 6929558 TI - Autoradiographic investigation of dentin production in rat incisors after vincristine administration. AB - 0.7 mg/kg VCR was administered intravenously to nine rats in three experimental groups. One hour after VCR injection the animals were injected with 3H-proline. The animals were sacrificed 1.5, 5 and 24 h after the VCR administration, and by comparison with nine control animals similarly injected with sodium chloride solution and 3H-proline, it was shown that VCR causes an early, intracellular retention of labeled proline in the odontoblasts, an abnormal intracellular distribution of labeled material and a generally decreased secretion of dentinal matrix from the odontoblasts in the maxillary incisors. The severity of the effects were shown to vary in different parts of the incisors. PMID- 6929559 TI - Immune response in rats against lipopolysaccharides of Fusobacterium nucleatum and Bacteroides oralis administered in the root canal. AB - Lipopolysaccharides (LPS) prepared from one strain of Fusobacterium nucleatum and one strain of Bacteroides oralis were examined for immunological responses in rats. The LPS were applied to the pulp chamber of the two mandibular incisors. Using the plaque forming cell (PFC) method both antigens showed a rapid IgM response in the spleen, and a slower one in the submandibular lymph nodes. In comparison with the IgM response, the IgG response was somewhat slower and weaker for LPS of Bacteroides, while for LPS of Fusobacterium it was hardly detectable. After about 3 weeks both antigens gave a significant antibody titer in serum. The results showed that locally applied antigens of oral microorganisms can stimulate to an immune response both in the lymph nodes and the spleen resulting in circulating antibodies. The nature of this response is dependent on the chemical characteristics of the LPS-antigen. PMID- 6929560 TI - Bone tissue formation within a sintered microporous glass-fiber network implanted in extraction sockets in the rat. AB - Implants were prepared by sintering glass-fibers into a three-dimensional network with meshes smaller than 20 micron. Oblong 5 x 2 x 0.15 mm sheets of the test material were implanted in maxillary incisor alveoli in eight white rats. The alveoli were closed with a suture in the overlying mucosa. After 3 months the animals were sacrificed and sections from the site of implantation prepared. In three animals only root remnants were found but in the remaining five the implants were wholly or partially embedded in bone tissue. Sections studied with transmitted light, microradiography, and scanning electron microscopy showed that mineralized tissue had also formed within the pores of the network. The intimate contact between the individual fibers and the bone within the network was corroborated through microchemical analysis (EDX). PMID- 6929561 TI - Pattern of age related bone loss in mandibles. AB - A study was carried out to analyze the pattern of the age related bone loss in the mandibular cortex and to establish normal values and the observed range of morphometric variables on microradiograms of bone sections taken from a well defined site anterior to and below the mental foramen. Specimens were obtained from 100 Danish subjects with no known systemic bone disease or severe mandibular atrophy. Microradiograms of 100-micron-thin undemineralized vertical ground cross sections were produced. An electric point-counting system was used for the determination of 1) percentage bone mass, 2) mean cortical width (MCW), and 3) the percentage of Haversian canals with resorption surfaces. The analysis showed that cortical porosity and the percentage of Haversian canals showing resorption are unrelated to sex and increased after the age of 50. MCW and absolute bone mass (MCW x % bone mass) are greater in males than in females and show a parallel age related decrease after the age of 50. Furthermore, the age related increase in cortical thinning and porosity is dependent on the individual as well as on age. Marked individual variation confined the use of these parameters to group analysis. PMID- 6929562 TI - Quantitative evaluation of the morphology of the inner surface of composite restorations. AB - The aim of the present study was to develop a method for quantitative evaluation of the morphology of inner surfaces of composite resin restorations. Twelve restorations made in vivo using the acid etch technique were examined in a scanning electron microscope at a magnification of x 2000. 2500 predetermined areas (6300 micron2 each) on the inner surfaces of the fillings were scored from 0 to 3 with respect to the impression of their rendering of morphologic details from the etched cavity walls. Based on all the scorings and parts of the scorings, estimates for the enamel and for the dentin relief on each of the fillings were calculated. The statistical comparison of these estimates that approximately 50 areas per filling might be scored to attain an objective and reliable quantitation of the surface morphology. PMID- 6929563 TI - Ultrastructural features of the epithelial-mesenchymal interface in an ameloblastic fibro-odontoma. AB - The ultrastructural features of the epithelial-mesenchymal interface in a case of an ameloblastic fibro-odontoma was studied with special reference to possible signs of "inductive" processes. In most parts of the tumor, the odontogenic epithelium was separated from the connective tissue by a thick rim of a finely filamentous meshwork in which a basal lamina was occasionally observed. Mesenchymal cells were seen to touch the filamentous meshwork but no membrane bound matrix vesicles were recorded. Small areas of dentin-like tissue were found in the juxtaepithelial connective tissue while enamel-like areas and spherical calcified masses were encountered in epithelial islands. The organic matrix in relation to the enamel-like tissue consisted of either tubular fibers or a fine granular material. It was assumed that the tubular matrix component directed the formation of long enamel-like crystals, and that the fine-granular matrix was degraded tubular fibers in which spherical calcified masses might arise. Spherical calcified masses could be found in separate follicles also where they were related to a fine-fibrillar matrix or collagenous material. The cell layers forming the wall of the islands had a great resemblance to those of an enamel organ, but the findings of dentin-free, enamel-like areas are not compatible with the inductive theory of normal odontogenesis. PMID- 6929564 TI - Autoradiographic investigation of proliferative responses in rat incisor pulp after vincristine administration. AB - -0.7 mg/kg VCR was given to nine rats in three experimental groups. Twenty-three hours after VCR injection the animals were injected with 3H-thymidine. The animals were sacrificed 24, 48 and 72 h after the VCR injection, and by comparison with nine control animals similarly injected with sodium chloride solution and nucleotide, it was shown that VCR causes a delayed migration of pulp cells from the proliferative pool and a small but distinct inhibition of the incisal growth of the incisors. The growth inhibition corresponded to the normal growth over a 24-h period in non-VCR-injected animals. PMID- 6929565 TI - Chromosome aberrations and prognosis in preleukaemia. AB - 24 patients with preleukaemia were cytogenetically studied by the G-banding staining technique. All patients developed later frank acute non-lymphocytic leukaemia and died. 13 patients had a completely normal karyotype (NN-patients) with a median survival time of 8 months. 6 patients had both normal and abnormal metaphases (AN-patients) with a median survival time of 18.5 months, while 5 patients had abnormal metaphases only (AA-patients) with a median survival time of 3 months. PMID- 6929566 TI - Normal and leukaemic human haemopoietic cells in diffusion chamber. A morphological and functional CFU-C study. AB - Leukaemic human bone marrow and peripheral blood cells were cultured for 25 d in diffusion chambers implanted into cyclophosphamide treated mice. Normal bone marrow cells were cultured simultaneously. These cells were studied both morphologically and functionally (CFU-C). The leukaemic cells behaved heterogeneously, 2 groups being distinguishable in accordance with their initial in vitro growth pattern (1: no growth or microcluster growth. 2: macrocluster growth). Group I showed progressive cellular death with a diminution of granulocytic progenitors and the appearance of a predominantly macrophagic population. This behaviour resembled that of the control group. The initial microcluster growth pattern remained identical throughout the entire culture period. Group 2, after considerable cellular death up to d 5, showed an explosive proliferation of the granulocytic progenitors and incomplete differentiation (up to myelocyte). The initial macrocluster growth pattern remained identical. PMID- 6929567 TI - Acute myeloblastic leukaemia in sarcoidosis treated with methotrexate. AB - A 60-year-old man with sarcoidosis of skin and knee joints was treated with prednisone and methotrexate (MTX). A total of 590 mg MTX was given over two periods each of 3 months duration. 4 1/2 years after the first MTX dose he developed acute myeloid leukaemia. Only one more case of acture myeloid leukaemia following MTX treatment for a benign disease has been described, and until further cases have been reported the correlation might be considered a matter of simple coincidence. PMID- 6929568 TI - Alkaline phosphatase activity of chronic granulocytic leukaemia neutrophils in agar culture. AB - We measured the concentration of granulocyte-committed progenitor cells (CFU-c) and the alkaline phosphatase activity of neutrophils harvested from colonies cultured from the peripheral blood of 30 patients with high-count chronic granulocytic leukaemia (CGL) in the chronic phase. Neutrophils in colonies cultured from marrow of normal donors or patients with acute myeloid leukaemia in remission served as controls. CFU-c numbers in CGL peripheral blood were on average 3 times higher than in normal marrow (130.1 +/- 126.2 (SD) versus 43.0 +/ 25.2 per 1 X 10(5) cells plated, respectively). The mean NAP scores in cultured CGL neutrophils were substantially higher than control values (89.9 +/- 48.0 versus 55.9 +/- 33.0 units, respectively). There was a tendency for peak values of NA in culture to be reached at earlier points in CGL cultures with high CFU-c numbers (i.e. high proliferative rates) than in those with lower CFU-c numbers (lower proliferative rates). Our data accord with the concept that low NA levels in CGL in vivo result from modulating influences external to the neutrophil. PMID- 6929569 TI - Inherited levels of A and B types of monoamine oxidase activity. AB - In establishing the role of inherited variations in levels of monoamine oxidase (MAO) activity in neuropsychiatric diseases, it is important to measure levels of both A and B types of activity as they appear to be under separate genetic control. Levels of A and B types of activity can be evaluated in fibroblasts and platelets, respectively. A number of genes could be involved in determining levels of activity, including those coding for the catalytic and noncatalytic subunits of the enzyme, as well as those coding for enzymes involved in covalent attachment of the flavin cofactor, other processing steps, degradation of MAO, and lipid metabolism. Different genes may be critical in controlling activity levels in various cell types depending on differential expression of the genome. In order to establish the molecular basis of variation in activity, techniques should be employed to assess the structure and conformation of the enzyme, as well as the number of enzyme molecules and their interaction with other cellular components. Only by understanding the genetic and environmental factors controlling levels of A and B types of MAO activity can we hope to evaluate and manipulate the role of MAO in human neurophysiology. PMID- 6929570 TI - Sixty nine year old Caucasian male with low grade fever and upper respiratory symptoms of three week duration. PMID- 6929572 TI - Cranial fasciitis: nodular fasciitis of the head. AB - An infant was noted at birth to have a lesion over the left coronal suture fixed to both the skin and periosteum, which was identical histologically to nodular fasciitis. This lesion has been described in the literature in various locations, but rarely in the scalp, and not in newborns. PMID- 6929571 TI - A study of endometrial carcinoma and potential precursor lesions (Part II). PMID- 6929573 TI - Plasma levels of protease inhibitors in acute myeloid leukemia at the onset of the disease and during antiblastic therapy. PMID- 6929574 TI - [Glycogenoses. Diagnosis and classification]. PMID- 6929575 TI - [Roundworm infection (Toxocara and Toxascaris) in dogs in the Netherlands (author's transl)]. AB - The incidence of roundworm infections was determined by examination of the faeces in a total number of 544 adult dogs in the Netherlands during the period from 1972 to 1977. The incidence of roundworm infections varied from 13 to 34 per cent (average 22.9 per cent) during this period, from 2 to 31 per cent (average 14.5 per cent) for Toxocara canis infections, from 8 to 15 per cent (average 11.2 per cent) for Toxascaris leonina infections and from 0 to 11 per cent (average 2.8 per cent) for combined T. canis and T. leonina infections. PMID- 6929576 TI - [Electropotentials of pathological dentogingival pockets in parodontosis]. PMID- 6929579 TI - [X-ray characteristics of the jaw bony tissue structure depending on age]. PMID- 6929577 TI - [Use of low temperatures for treating parodontal and oral mucosal diseases]. PMID- 6929578 TI - [Microhardness changes in the hard human dental tissues after radiation therapy]. PMID- 6929580 TI - [Experience in using hyperbaric oxygenation in the overall treatment of parodontosis]. PMID- 6929582 TI - [Skin hydrophilic test in chronic, recurrent aphthous stomatitis]. PMID- 6929581 TI - [DNAse treatment of herpes of the maxillofacial area]. PMID- 6929585 TI - [Disturbances of cardiovascular activity and their correction in radical operations for maxillofacial tumors]. PMID- 6929584 TI - [Alveolitis treatment using the amnion]. PMID- 6929583 TI - [Use of hyperbaric oxygenation in the therapy of maxillofacial actinomycosis]. PMID- 6929589 TI - [Use of transfusion therapy in stomatology]. PMID- 6929588 TI - [Cytotoxic action of filling materials on human embryonic fibroblast cell cultures]. PMID- 6929590 TI - [Sjogren's syndrome in the clinical picture of collagen diseases]. PMID- 6929591 TI - [Comparative evaluation of the types of anesthesia during the osteosynthesis of mandibular fractures using metal pins]. PMID- 6929592 TI - [Specific immunoprophylaxis of postoperative inflammatory complications in the stomatological polyclinic]. PMID- 6929587 TI - [Combined general anesthesia with fortral and sombrevin in ambulatory stomatological practice]. PMID- 6929586 TI - [General anesthesia in odontogenic inflammatory processes of the perimaxillary soft tissues]. PMID- 6929593 TI - [Characteristics of the pathological degree of tooth wear in coal mine workers]. PMID- 6929594 TI - [Orthopedic treatment of habitual dislocation of the meniscus of the temperomandibular joint]. PMID- 6929595 TI - [Role of local and general factors in the origin of certain forms of glossalgia]. PMID- 6929597 TI - [Late results of removing secondary deformations of the occlusal surface of the dental arches by an apparatus and surgical method]. PMID- 6929599 TI - [Electromyographic characteristics of the state of the masticatory muscles in children with maxillary deformations in congenital cleft palate before and after an operation]. PMID- 6929598 TI - [Choice of the general anesthesia method in children in operations for congenital cleft palate]. PMID- 6929600 TI - [Structure of the facial skeleton in Robin's syndrome]. PMID- 6929596 TI - [Effect of thyrocalcitonin on metabolism in rat parodontal tissues]. PMID- 6929603 TI - [Treatment of young infants with congenital developmental pathology of the face and jaws]. PMID- 6929604 TI - [Intravital dental enamel solubility and its macroelemental makeup in caries resistant and caries-active persons]. PMID- 6929601 TI - [Electrode placement characteristics in registering the bioelectrical potentials of the mimetic muscles of the perioral area in children with congenital harelip]. PMID- 6929606 TI - [Experience with the use of electroroentgenography in stomatology]. PMID- 6929607 TI - [Project for the model physician graduate in the specialty of stomatology]. PMID- 6929605 TI - [Anesthesia in stomatological interventions on patients with an allergic anamnesis]. PMID- 6929608 TI - [Comparative evaluation of the antibiotic resistance of staphylococci in stomatological diseases]. PMID- 6929609 TI - [Effect of glucocorticoids on the mineral metabolism of the rat maxillary and femoral bones]. PMID- 6929602 TI - [Functional state of the maxillofacial muscles in 4- to 6-years-old children according to electromyographic study data]. PMID- 6929610 TI - [Chloramine color test for novocaine]. PMID- 6929611 TI - [Delay in the development of the tongue]. PMID- 6929612 TI - [Method of obtaining roentgenograms of the upper and lower teeth on 1 film]. PMID- 6929613 TI - [Press-molded protective plate in uranoplasty]. PMID- 6929614 TI - [Stomatological status of a patient with Ota's nevus]. PMID- 6929615 TI - [Use of an electromagnetic field for treating parodontosis]. PMID- 6929616 TI - Bifunctional enzyme activity at the same active site: competitive inhibition kinetics with 3 alpha/20 beta-hydroxysteroid dehydrogenase. AB - 20 beta-Hydroxy-5 alpha-pregnan-3-one (HPO) is a competitive inhibitor of reduction by 3 alpha/20 beta-hydroxysteroid dehydrogenase (3 alpha/20 beta-HSD; E.C.1.1.1.53) of 17 beta-hydroxy-5 alpha-androstan-3-one (DHT; 3 alpha-activity; Ki = 4.6x10(-5)M), and of 6 beta-acetoxyprogesterone (6 beta-AP; 20 beta activity; Ki = 4.34x10(-5)M). HPO and DHT inhibit affinity alkylation of 3 alpha/20 beta-HSD by 6 beta-bromoacetoxyprogesterone (6 beta-BAP). The facts that 1) enzyme 3 alpha-activity and 20 beta-activity are both competitively inhibited by HPO with practically identical Ki-values, 2) 6 beta-BAP is solely a 20 beta activity substrate for 3 alpha/20 beta-HSD, 3) one mole of 6 beta-BAP reacts with one mole of 3 alpha/20 beta-HSD to simultaneously inactivate 3 alpha- and 20 beta activity, and 4) inactivation of 3 alpha/20 beta-HSD by 6 beta-BAP is inhibited by DHT (a C19-steroid) or HPO (a C21-steroid), support the view that the same active site of 3 alpha/20 beta-HSD possesses both 3 alpha- and 20 beta-activity. Bifunctional activity at the same active site is considered for other steroid specific enzymes in female mammalian reproductive systems. PMID- 6929618 TI - Thymidine phosphorylase: a possible marker of cell maturation in acute myeloid leukaemia. AB - Thymidine Phosphorylase activity has been measured in two populations of human Acute Myeloid Leukaemia cells (AML) and in normal human macrophages. During short term culture in vitro of AML cells the activity of this enzyme increases progressively and approaches that of normal non-dividing macrophages at a time when the leukaemia cells in culture show evidence of maturation as assayed by functional, enzymatic and morphological criteria. It is suggested that the level of Thymidine Phosphorylase activity may be a marker of maturation in AML. PMID- 6929617 TI - Selective mitochondrial alterations induced by a single dose of daunorubicin or 4 demethoxydaunorubicin in mouse ventricular myocardium. AB - The ventricular myocardium of CD1 mice given a single high dose (LD50) of daunorubicin (DNR) or its derivative, 4-demethoxydaunorubicin (4DD), was studied under the electron microscope. Severe degenerative alterations were observed, but only in the mitochondria in myocardial tissue samples taken 3 and 7 days after treatment. This suggests that mitochondrial lesions might play an important role in the pathogenesis of anthracycline myocardipathy. Furthermore, the nucleolar segregation phenomenon, already described in experimental doxorubicin myocardiopathy, was not observed in the myocardial samples taken 1 and 3 h after DNR or 4DD injection: this fact may be interpreted, without excluding a possible DNA-mediated toxic mechanism, as the result of different kinetic behaviour of DNR and 4DD compared to doxorubicin. PMID- 6929619 TI - What is a shunt? Concepts of central shunts and effective flow and a method for graphical presentation of circulatory quantities and their interrelations. AB - The terminologies commonly used in descriptions of abnormal patterns of blood flow in patients with congenital heart defects are valid only in the case of simple abnormal communications in an otherwise essentially normal cardiac anatomy. In more complex cases the expressions are unambiguous and elucidatory only when qualified further, but then the terminology becomes cumbersome. Much might be gained in clarity by considering the combined ventricular output as having four components: two are essential, and equal in size; they constitute the effective flows to the systemic and pulmonary arterial trees of blood from the pulmonary and systemic veins, respectively. The other two are recirculated systemic and pulmonary flows and may or may not exist; they may be referred to as blue and red shunts, respectively. Here, 'shunt' is defined as a by-pass of the capillary system to which a given blood flow is destined. The red and blue shunts are both central--as distinct from peripheral ones, where the by-pass links arteries and veins in one of the two circulations. Adoption of the concepts of central shunts and effective flow as defined here would facilitate a rational and consistent quantitative analysis of the circulation in individual cases irrespective of variations in cardiac anatomy. It would also make it possible to present in instantly understandable diagrams the magnitudes and interrelations of such variables as the oxygen consumption, the blood's oxygen capacity and the oxygen contents of the blood in the great vessels connecting the heart and the two circulations, the combined ventricular output and its components, the mean pressure difference across the pulmonary circulation and the pulmonary vascular resistance. A graph blank for such a presentation is proposed, and its application in cases with and without central shunts is exemplified. PMID- 6929621 TI - [Interscapulothoracic amputation in treating malignant tumors of the upper extremity and shoulder girdle]. AB - Fifty one patients with bone sarcomas (42 cases) and soft tissue sarcomas (9 cases) were subjected to interscapulo-thoracic amputation. Five year survival was noted in 42,5% of cases with primary bone sarcomas. The survival was dependent first of all on the histologic character of the tumor: it is higher in chondrosarcomas (50,2%) and lower in osteosarcomas (25,4%). Interscapulo-thoracic amputation is an obligatory but helpful surgical intervention. PMID- 6929620 TI - Myocardial infarction without coronary occlusion. A study with a new experimental method in sheep. AB - An experimental method for induction of myocardial infarction in sheep is described. This leads to local infarction without arteriographically demonstrable lesions in the coronary arteries. A 0.95 mm thick thermosonde is introduced into a coronary artery through a catheter. The tip of the thermosonde is heated to 45 65 degrees C for 1-2 min and the thermosonde is then removed. On heating of the tip, infarction occurs instantaneously, as observed both macro- and microscopically and at left ventricular angiography. The thermosonde method described makes it possible to induce myocardial infarction in sheep in a reproducible way and is therefore applicable to studies of the pathogenesis of infarction. This justifies its use in investigations of the effect of myocardial infarction on the anatomy and function of the left ventricle and coronary arteries. PMID- 6929622 TI - Treatment of osteogenic sarcoma that had metastasized to the lungs--25-year survival of a patient. PMID- 6929623 TI - [Problems of suicide in vorarlberg (author's transl)]. AB - Socio-psychiatric relevant data were excerpted from our own records of patients whose cases had been followed up for years and from 67 questionnaires on suicide prophylaxis established by the "Work Group for Preventive and Social Medicine" (Arbeitskreis fur Vorsorge- und Sozialmedizin). The following items were dealt with: age and sex distribution, social status, habitation structure, kind of suicide attempt and, particularly, its diagnostic category. The analysis and evaluation of the data formed the basis for an attempt to work out a "new group" which would reach further than the classical diagnostic groups and which has not yet been reported in the literature. The new group is distinguished by loss of cognitive and emotional stability. This socio-psychiatric study closes with a discussion of the therapeutic aspects of prevention and intervention, the significance of which is emphasized by the high rate of repeated suicide attempts. PMID- 6929624 TI - [Influence of risk factors on the angiographic findings of occlusive cerebrovascular disease (author's transl)]. AB - The angiographic findings in 69 patients suffering from ischaemic stroke or transient ischaemic attacks were compared with the clinical data. The incidence of extracranial stenoses increases with age and is higher in patients with hypertriglyceridaemia and with occlusive arterial disease of the heart or the limbs. Hypertensive patients show extracranial stenoses less frequently, but a greater number is without any visible stenoses in the vessels supplying the affected part of the brain. The influence of the diastolic blood pressure on the distribution of the angiographic findings is greater than that of the systolic pressure, but if the diastolic pressure exceeds 105 mm Hg, the incidence of the different angiographic findings is equalized. Among female patients there are more without visible stenoses in the vessels supplying the affected part of the brain. Blood glucose and cholesterol showed no influence on the distribution of the angiographic findings and the incidence of intracranial stenoses was independent of any of the investigated factors. These results support the hypothesis that different risk factors cause different forms of arterial occlusive disease. PMID- 6929625 TI - [Densitometric evaluation of angiocinematographic x-ray films in cerebrovascular diseases (author's transl)]. AB - 21 patients suffering from cerebrovascular diseases were examined by means of angiocinematography. The 37 X-ray films were taken under standardized conditions of exposure and development, and were evaluated by use of densitometry. The flow speed and the blood volume/min were measured in the internal carotid artery, as well as the arterial transit time from the carotid siphon to standardized measuring points in the three branch groups of the middle cerebral artery. The haemodynamic parameters obtained from the clinically affected hemispheres or branch groups were compared with those obtained from the clinically non-affected. The aim of this study was to attempt to make a contribution towards the understanding of haemodynamic changes in connection with cerebrovascular diseases. PMID- 6929626 TI - [Urological complications in patients with multiple sclerosis (author's transl)]. AB - 63 patients with multiple sclerosis underwent urodynamic evaluation. Hyperreflexia of the bladder was found in 64% and areflexia in 8%. Hypertrophy or sclerosis of the bladder neck (internal sphincter) was detected in 27% of the patients and a spastic external sphincter (dyssynergia) was encountered in 57%. 16 patients were admitted for surgery: 9 for TUR of the bladder neck, 5 for percutaneous selective sacral nerve block, 2 for ileal diversion, 2 for prolonged bladder distension and 1 for nephrectomy for staghorn calculi of the renal pelvis. Highly effective conservative therapy is available in the form of Lioresal for treatment of the hyperactive detrusor muscle and Dibenzyran - an alpha-adrenergic blocking agent - to relieve bladder neck spasticity. PMID- 6929627 TI - [Reasons for lumbar syndromes after disc operations (author's transl)]. AB - This investigation presents the findings in 105 patients after disc operations who required renewed in-patient treatment mainly because of their resistance to therapy and/or recurrence of the lumbar syndrome. A number of factors were found to be implicated in providing a reason for unsatisfactory results after operations for prolapsed lumbar intervertebral discs. It must be postulated that interfering factors like ligamental pain, restricted movement, participation of the hip, psychological aspects, polyneuropathics and focal occurrence have to be taken into consideration already preoperatively in the diagnosis, indication for operation and therapy. Also with post-operative complaints special alteration must be paid during rehabilitation to those factors quoted above, as well as to direct post-operative complications like inflammation and scar. PMID- 6929629 TI - [Neonatal small left colon syndrome: a finding of only radiological or also clinical significance? (author's transl)]. AB - The finding in the literature that the neonatal small left colon syndrome can be present in newborn infants of diabetic mothers without relevant clinical signs led us to perform contrast enema investigations of the colon in 20 newborn infants of insulin-dependent diabetic mothers. Among these only one infant, with signs of intestinal obstruction, had the small left colon syndrome. During the same period the neonatal small left colon syndrome was diagnosed in 4 out of 10 mature newborn infants of healthy, non-diabetic mothers who underwent contrast enema investigation because of intestinal obstruction. The concepts of the pathogenesis of the neonatal small left colon syndrome and the importance of this form of functional intestinal obstruction in the newborn are discussed together with the presumptive relationship to severe gastrointestinal complications such as e.g. necrotizing enterocolitis, seen with increasing frequency in artificially ventilated newborns. PMID- 6929628 TI - [Arteritis in cerebral inflammatory diseases. Diagnostic value of angiography (author's transl)]. AB - Cerebral angiography may sometimes show up inflammatory changes in the brain arteries in cases of tuberculous and acute purulent bacterial meningitis. The arteries at the base of the brain are predominantly affected, in some cases together with peripheral branches. Normal angiograms or non-specific alterations may be expected in patients suffering from non-purulent meningitis and encephalitis. Patients with luetic diseases show circumscribed or diffuse vessel wall lesions which cannot be differentiated from alterations caused by arteriosclerosis. The results are presented of 15 patients suffering from inflammatory diseases of the central nervous system of different aetiology. The morphology and the distribution of the arterial changes in the cerebral angiogram are discussed. PMID- 6929630 TI - [Use of monomeric trains in diagnosis of twins (author's transl)]. AB - The principle of estimating the probability of monozygosity based on Bayes' formula is outlined for tweins with unknown parental genotypes. Tables based on Austrian gene frequencies are given for the common blood groups for easy computing of the chance of monozygosity. PMID- 6929632 TI - [The nutritional value of raw breast milk in feeding premature babies with a birth weight of below 1500 g (author's transl)]. AB - Raw milk expressed from the infant's own mother is the ideal initial nutrient, even for premature babies with a birth weight of below 1500 g. When these babies start to grow very rapidly from about the third week of life on, this milk is probably nutritionally inadequate. For babies with birth weights above 1500 g raw milk provided by the natural mother is the ideal nutrient at all times. This is a report of a simple and inexpensive system which enables us to collect breast milk and to test the bacterial count of each sample of milk. This milk is given to the babies without any heat treatment if the bacterial count is 10(3) per ml or less. Milk displaying bacterial counts of 10(4) to 10(5) per ml is boiled. Milk with higher bacterial counts is thrown away. Intensive counselling of the mothers as regards personal hygiene, with particular emphasis on breast hygiene and pumping technique improves the quality of the milk. In fact, 43% of the milk samples delivered to us have bacterial counts of below 10(4) per ml. PMID- 6929631 TI - [Serum levels of 25-hydroxycholecalciferol (25-OH-D3) in children of different age groups (author's transl)]. AB - Serum 25-OH-D3 levels were determined in 78 children aged 6 weeks to 15 years, in March 1977 and March 1978 in Vienna. The total number of probands was divided into age groups, each comprising a range of 3 years. The average value with 1 SD. found over the whole age range was 48.3 +/- 25.75 nmol/l (i.e. 19.4 +/- 10.34 ng/ml). Somewhat higher levels were found in the age groups 3 to 6 and 6 to 9 years, with a slight decrease in the later age groups, but no significant differences were detected. The obtained values seem to represent the "normal" 25 OH-D3 serum levels of our population in the above-mentioned age range. PMID- 6929633 TI - [Carrot soup analysis (author's transl)]. AB - The sodium and potassium concentration, the osmolality and the carbohydrate content were determined in carrot soups prepared in 4 different children's hospitals and used as oral therapy for infantile diarrhoea. The results were compared with the sugar/electrolyte solutions increasingly recommended for oral rehydration. If adequately prepared (Moro),the carrot soup can replace enteral loss of sodium and potassium and contains sufficient glucose and sucrose as free sugars to ensure optimum sodium and water absorption in the jejunum. The addition of high osmolar glucose in a commercially available carrot food (Hipp) used in the preparation of the soup in two hospitals increases its osmolality, which might provide an extra strain on the affected intestine of these ill infants. PMID- 6929634 TI - [Assessment of respiratory function by body plethysmography (author's transl)]. AB - The assessment of respiratory function by means of body plethysmography is particulary important in obstructive respiratory disorders. The conventional interpretation considered the bronchial resistance to be a relation between the alpha- and beta-slopes. The individual examination of these factors under work stress, histamine challenge and hexoprenaline broncholysis shows that the changes in the resistance will mainly be dependent on the beta-slope, even in the presence of a paradox response of the alpha-slope and, therefore, a reverse change in the intrathoracic gas volume. Therefore the beta-slope alone can be used to give satisfactory information about the bronchial resistance as an alternative method or, in the case of any difficulty in getting an airway shutter slope, for example, in paediatrics. PMID- 6929639 TI - Salivary HBsAg in hepatitis B infection. AB - Hepatitis B surface antigen (HBsAg) was detected by solid phase radioimmunoassay (RIA) in mixed saliva of 15 out of 50 antigenemic patients. The salivary antigen was present in low titers for a short period of time in the acute stage of illness. Occult blood was detected in most mixed saliva samples. In parotid saliva neither HBsAg nor occult blood was found. Salivary HBsAg is probably due to admixture of blood or exudate. PMID- 6929635 TI - Jaw muscle activity during chin-tapping. AB - Electromyographic (EMG) activity was recorded from the masseter, the anterior temporal and the anterior digastric muscle on the right side of ten dental students when taps were administered upwards or downwards to the chin. The experiment was performed both with relaxed jaw muscles and with contracting depressor muscles. Pairs of intracutaneous platinum hook electrodes were used for the masseter and temporal muscles while concentric needle electrodes were inserted into the anterior digastric muscles. The mean latency of the jaw-jerk elicited in the relaxed masseter muscle when tapping downwards on the chin was 7.8 msec and in the temporal muscle 8.4 msec. The corresponding values of the latency during jaw opening against resistance from the investigator's finger was 8.2 msec and 9.0 msec. During upward tapping on the chin recordings from the anterior digastric muscle showed obvious changes in EMG activity, the latency ranging from 13 to 34 msec. Thus, compared to the latency of the jaw-jerk in the masseter and temporal muscles, which contain numerous muscle spindles, recordings from the anterior digastric muscle, where muscle spindles are thought to be either lacking or few in number, showed no signs of a monosynaptic reflex. PMID- 6929636 TI - Release of formaldehyde from denture base polymers. AB - The release of formaldehyde in an aqueous environment at 37 degrees C from the surface of heat-polymerized, and auto-polymerized dough and pour type acrylic denture base materials was determined quantitatively. The analytical method used was based on determination of the reaction product of formaldehyde and dimedone by means of high performance liquid chromatography (HPLC), i.e. the method is spesific for formaldehyde. Chemical model reactions were carried out to simulate possible reaction mechanisms for the formation of formaldehyde in denture base polymers. The quantities of released formaldehyde was dependent on the processing conditions and composition of the material. Heat-polymerized denture base materials released considerably less formaldehyde than the auto-polymerized dough and pour types of materials. PMID- 6929637 TI - Inhibitory effect of a fluoride-containing amalgam on development of cavity wall lesions in vitro. AB - This study aimed to compare caries-like lesions produced aroung fluoride containing amalgam and conventional amalgam fillings in vitro. Class V cavities were prepared in 90 extracted premolars, a fluoride-containing amalgam was inserted in 45 cavities (experimental group) and a conventional amalgam in 45 cavities (control group). After three months in an acidified gelatin solution, a longitudinal ground section passing through the cavity was prepared from each tooth. The sections were imbibed in water, quinoline and some in air before examination by polarized light microscopy. When imbibed in Canada balsam the sections were photographed and areas of demineralization in the enamel measured morphometrically. Some sections were studied by microradiography and electron microprobe analysis. Numerical scoring of the histological observations revealed significantly lower values for enamel and dentin cavity wall lesions in the experimental group, while the scores for the outer lesions were not statistically different between the two groups. The mean extension of enamel wall lesions was significantly lower in the experimental group, while no difference was observed in the outer lesions. A zone of increased mineralization in the enamel cavity walls was a frequent finding in the experimental group. This study has shown that fluoride-containing amalgam has an inhibitory effect on the development of experimental cavity wall lesions in vitro. PMID- 6929640 TI - The timing and duration of adolescent growth. AB - The adolescent growth of 212 randomly selected Swedish urban children has been investigated by using a graphical analysis of unsmoothed increments of height. The adolescent growth period has been divided into the pubertal spurt and the postpubertal period. On average, the pubertal spurt began at 10.0 years in girls, and 12.1 years in boys and ended at 14.8 years and 17.1 years, respectively. In both sexes peak height velocity occurred two years after the onset of the spurt (12.0 years and 14.1 years). Growth terminated at 17.5 years in girls and 19.2 years in boys. The standard deviation of the age at the occurrence of the various growth events is about one year in both sexes. The duration of the spurt did not differ between the sexes but the postpubertal period was significantly longer in girls. To include the total range of adolescent growth variability, the age range 6 -- 20 years in girls and 9 -- 23 years in boys must be considered in a Swedish population. PMID- 6929641 TI - Effect of instruction and motivation on dental knowledge and behavior among wearers of partial dentures. AB - Patients receiving partial dentures were divided into three groups. One "maximum" group was taught and motivated, both individually and as a group, as thoroughly as possible. The second "medium" group was given instruction sheets describing the essential facts related to the cleaning and maintenance of teeth and dentures., but no individual instruction and motivation were provided. In the third "minimum" group the obtaining of information was left entirely to the initiative of the patients themselves. By the end of the period of treatment, the patients' knowledge was in proportion to the amount of teaching they had received. As regards dental health behavior, the groups did not differ significantly from one another, although there were some indications that increased knowledge and motivation had promoted positive oral hygiene habits. A year after the completion of treatment the positive behavior habits were markedly fewer in all groups, and no longer bore any relation to the amount or type of instruction or motivation given. PMID- 6929642 TI - Sealing of preventively enlarged fissures. AB - The occlusal fissures of 156 permanent first molars in 63 children, 7--8 years of age, were sealed with a chemically polymerizing material (Delton). Deep and narrow fissures were opened up with a pointed diamond before etching and sealing. The treatment was performed by untrained dental students. The patients were called back for treatment every 6 months. 2/3 of the patients were followed up for a period of 2 1/2 years. After that period the retention of sealants was 93% (74 sealants) in ground deep fissures and 88% (28 sealants) in unground shallow fissures. PMID- 6929638 TI - Deteriorating effect of occlusal disorders on the periodontium of rats with experimental arteriosclerosis. AB - The periodontal effects of food consistency and of experimental occlusal stresses were clinically studied with healthy and arteriosclerotic rats. Experimental arteriosclerosis was induced with a hypercholesterolemic diet continued for 6 -- 12 months. By using food that was finely powdered and moistened, mechanical irritation of the periodontium was reduced to a minimum. The special occlusal and gingival irritants lasting six weeks were an occlusal overload with an overhigh amalgam filling, or an occlusal hypofunction caused by extracting the antagonist tooth. The arteriosclerotic animals with experimental occlusal stress had gingival changes adjacent to the loaded tooth distinctly more often than around the control tooth on the contralateral side of the mandible of the same animal (P less than 0.001). The changes seen were local redness and inflamation, and an excessive hyperplastic growth of the gingiva. The gingival changes on the stressed side in control animals were generally slight and the difference compared to the contralateral side was not statistically significant. The control animals showed recession of the gingiva more often than hyperplastic growth of same. In both groups of animals food impaction and deposit of calculus had increased around the teeth that were in occlusal hypofunction. The inflammatory changes were more frequent in the arteriosclerotic animals than in the controls. The cause of the deterioration in the ability to repair tissue damage in arteriosclerotic animals is discussed. PMID- 6929644 TI - A multiprofessional study of patients with myofascial pain-dysfunction syndrome. II. AB - One hundred and thirteen female patients with myofascial pain-dysfunction (MPD) syndrome were examined by a dentist and a psychiatrist. One hundred and eight of them were also examined by physiotherapists. Particular emphasis was given by the dentist to the types and duration of the chief complaints, the perceived severity of the MPD-symptoms and to the kinds of statements used in the anamnestic reports. Additionally the patients' perceived cause/origin of their symptoms, expectations regarding treatment, reactions to the different types of examination procedures and their reports of perceived daily life stress factors were taken into account. The patients were categorized according to the findings, and the results were compared to the psychiatrist's findings. Some basic clinical patterns were revealed. The results indicate that reports of oral symptoms may have symbolic value. It is concluded that a carefully performed clinical interview may provide the dentist valuable information useful in diagnosis and the choice of treatment. PMID- 6929643 TI - A multiprofessional study of patients with myofascial pain-dysfunction syndrome. I. AB - A research team comprising a dentist, a psychiatrist and two physiotherapists examined 113 female patients consecutively referred because of myofascial pain dysfunction (MPD) syndrome and, for comparison, 46 female patients who attended the dental clinic for a positively diagnosed dental problem. In both groups all subjects were Norwegians, nearly all in the age of reproduction and belonging to the upper social strata. Every second subject in the Comparison group had perceived some MPD-symptoms. The dentist's main findings in the MPD-patient group were high scores on the Anamnestic index and on the Dysfunction index, and moderate scores on the Occlusal index. The psychiatrist's main findings were high scores on restrained aggression and on anxiety, and tense control of emotions generally. The physiotherapists' findings were general muscular tension and inadequate respiratory function in an upright position. PMID- 6929645 TI - Marginal integrity of amalgam restorations. AB - Amalgam fillings using alloy with lathe--cut or spherical particles were placed in 38 Class II cavities of dental students. One part of each cavity was left unfinished in order to maximize differences in preparation quality, whereas the rest of the cavity was well finished. The cavities were replicated prior to restoration, after carving, polishing, and then after one year and four years. Quality evaluation was performed clinically using a scoring system for marginal integrity and by scanning electron microscopy of replicas. After four years the restorations filled with lathe-cut amalgam showed better quality than those made with spherical amalgam. No difference could be detected due to variations in the finishing technique of the margins. PMID- 6929647 TI - A qualitative and quantitative analysis of tertiary amines in restorative resins. AB - Previous investigations have shown that the type and the quantity of tertiary amine influence the properties of restorative resins. It was the purpose of the present work to analyze qualitatively and quantitatively the amines in commercial restorative resins. The amines were extracted with hydrochloric acid from chloroform solutions of the monomers. For the qualitative analysis the acid amine solution was made alkaline, the amine extracted with methylenechloride and isolated. The method of analysis was NMR-spectroscopy. The quantitative determination was performed by means of UV-spectra of the acid amine solutions. Sixteen brands were investigated, and three species of amine were identified. The amount of amine varied between 0.3% and 4% by weight of the monomer. Iit is probable that the information obtained will lead to a better understanding of the nature of restorative resins. PMID- 6929648 TI - Psychophysiological studies in schizophrenic patients selected on the basis of a "genetic marker". AB - Psychophysiological studies in schizophrenics have generally resulted in contradictory and inconclusive reports. The purpose of the present study was to determine whether a better psychophysiological separation of schizophrenic and control subjects could be accomplished by selecting them on the basis of a biological marker: the high plexus visualization score (PVS). Finger blood flow, skin temperature and electrodermal recovery rates were studied in 64 male schizophrenics (33 high PVS and 31 low PVS) and 24 male controls (10 high PVS and 14 low PVS) matched for age. All control subjects and 30 of the schizophrenics (16 high PVS and 14 low PVS) had been drug-free for at least 1 month. They were studied in a sound attenuated, temperature controlled room under 12 experimental conditions. The results demonstrate that, as predicted, schizophrenics with high PVS have the lowest finger blood flow rates, the lowest skin temperatures and the slowest GSR recovery rates of all groups studied. The largest difference in all three variables was found between high PVS schizophrenics and high PVS controls. The blood flow rates and the skin temperature were higher and the electrodermal responses were fewer in patients taking medications than in those receiving placebos. A suggestion of a bimodal distribution into "responders" and "non responders" was apparent only in patients receiving medications. PMID- 6929646 TI - A light microscopy study of pulps from traumatized permanent incisors with reduced pulpal lumen. AB - The pulps from 20 traumatized permanent maxillary incisors treated endodontically because progressive hard-tissue formation diminished the pulpal lumen, were studied with light microscopy. The tissue changes were characterized by a varied increase in collagen content. A marked increase in collagen content was associated with a marked decrease in number of cells. Areas of mineralized tissue resembling dystrophic mineralization were present in nine pulps. Osteoidlike tissue with included and lining cells was found adjacent to these mineralized areas in three pulps. In one pulp a moderate infiltration of inflammatory cells was noted, mostly lymphocytes. With the exception of the latter tooth, tissue changes in the pulps in no case warranted endodontic treatment. PMID- 6929649 TI - Studies on serum lipoproteins and lipid metabolism. Analysis of a random sample of 40 year old men. PMID- 6929650 TI - Calcium and phosphate metabolism in chronic renal failure, with particular reference to the effect of 1 alpha-hydroxyvitamin D3. PMID- 6929651 TI - Null cell (non-T, non-B) acute lymphoblastic leukemia terminating as malignant histiocytosis. AB - A case of null cell acute lymphoblastic leukemia (ALL) terminating in malignant histiocytosis (HMR) is discussed. The patient was a 22-year-old man who presented in January 1976 with ALL. Cell surface markers on the bone-marrow blasts showed that 1% formed rosettes with sheep erythrocytes (T cells) and 4% showed immunofluorescent staining for immunoglobulin; terminal transferase levels were elevated, confirming the diagnosis of null cell ALL. The patient was treated intensively with a combination of chemotherapy and cranial irradiation. One year after diagnosis, he was maintained in partial relapse (10-15% blasts). His terminal episode was characterized by pancytopenia. The bone marrow was replaced by malignant histiocytes. Cell surface membrane staining for cytophilic antibody was positive, whereas terminal transferase levels were in the range of nonlymphoid malignancies. PMID- 6929652 TI - Radiological case of the month. Giant cell pneumonia. PMID- 6929653 TI - Central nervous system involvement at presentation in acute granulocytic leukemia. A prospective cytocentrifuge study. AB - We have undertaken a perspective study of the prevelance of the central nervous disease in acute granulocytic leukemia (AGL). Thirty-nine newly diagnosed patients with AGL underwent cytocentrifuge examination of cerebral spinal fluid. Seven of the 39 patients had blast cells in their cerebral spinal fluid. All seven of these patients had acute myelomonocytic leukemia (AMML). No patients with other variants of AGL demonstrated blast cells in their cerebral spinal fluid. Other high risk factors associated with meningeal infiltration were elevated serum lysozyme levels, high peripheral white blood cell count, low age, splemomegaly and the presence of infiltration in other organs. The admission rates for patients with meningeal leukemia were lower and the survival time was shorter than in both the 32 noninvolved patients and the noninvolved patients with AMML. We believe that a lumbar puncture is indicated in all patients with newly diagnosed AMML. PMID- 6929654 TI - X-linked ichthyosis and X-linked placental sulfatase deficiency: a disease entity. Histochemical observations. AB - The combined occurrence of X-linked steroid sulfatase deficiency of the placenta and X-linked ichthyosis is reported in 6 unrelated boys. Placental steroid sulfatase deficiency was diagnosed on the basis of a very low total estrogen excretion (6 cases), verified prenatally by the dehydroepiandrosterone sulfate (DHEAS) loading test in 4 cases and postnatally by clinical investigations (6 cases) and by biochemical investigations (5 cases). In addition, microsomal arylsulfatase C (MAS) could not be detected in the placental homogenate of the five cases investigated. Lysosomal arylsulfatases were within the normal range. All boys developed well except for X-linked ichthyosis. In the 5 cases investigated the skin biopsy showed the same MAS deficiency histochemically in the granular layer of the epidermis as in the trophoblast cells. The same holds true for the skin of carriers. Steroid sulfatase activity of cultured skin fibroblasts from the boys was almost nil (3 cases). The histochemical technique offers a practical approach in the scientific investigation of keratotic conditions. PMID- 6929656 TI - Development of enzymatic conjugation and sulfation of bile acids in hamster liver. AB - In vitro levels of enzyme activity were measured in liver from fetal and developing hamsters to study the fetal immaturity and postnatal development of bile acid conjugation and sulfation. Sulfation and conjugation were measured in the same animals. Partial reactions of bile acid conjugation were assayed independently; sulfation of conjugated and unconjugated lithocholate was measured separately. From 3 days before to 3 days after birth, specific activity for sulfation of lithocholate and lithocholate conjugates was similar; lithocholate sulfation was 80% of adult levels. In older hamsters, specific activity for sulfation of lithocholate conjugates was significantly higher than that for lithocholate. Specific activities of both partial reactions of bile acid conjugation were 12% of adult levels from 3 days before to 3 days after birth. Thereafter both activities increased together; the ratio of glycine to taurine dependent conjugation was similar at all ages. The data suggest early development of a separate mechanism for lithocholate sulfation. Enzymes catalyzing bile acid conjugation and sulfation of bile acid conjugates exhibit maximal development after birth. PMID- 6929657 TI - Bone marrow biopsy changes following chemotherapy for acute leukemia. AB - Mulitple marrow core biopsy specimens obtained sequentially from each of 15 cases of treated acute leukemia were studied to established the sequence and frequency of histopathological events developing after chemotherapy. The features were separated into two overlapping phases: depletion and reconstitution. The depletion phase was characterized by progressive loss of hematopoietic cells which eventually left an empty stromal network of reticulin fibrils and numerous dilated sinusoids filled with fibrin. During the reconstitution phase, hematopoietic cell proliferation was variously accompanied by fat cell generation, fibroplasia, and bone formation. Fibrin exudation and serous atrophy of fat, two features previously ascribed to the marrow of leukemia after chemotherapy, were neither common nor characteristic. PMID- 6929655 TI - B-lineage prolymphocytic leukemia as a distinct clinicopathologic entity. AB - Prolymphocytic leukemia (PLL) was described originally by Galton and his colleagues as a special variant of chronic lymphocytic leukemia (CLL) with distinct clinical and hematologic features. Subsequent authors have described considerable heterogeneity in the clinical and immunologic features of PLL but have not dealt in detail with pathologic descriptions of their cases. Consequently, one might question whether PLL represents one disorder or a heterogeneous group of disorders. Three patients who satisfied Galton's original diagnostic criteria for PLL were examined by pathologic and immunologic methods. The spleens of these patients showed distinctive pseudonodular pathologic features. The malignant prolymphocytes were characterized as B-lineage by the presence of surface IgM and IgD, the expression of HLA-DR antigen, the absence of E-rosette formation, and the absence of natural killer cell activity. The existence of B-lineage prolymphocytic leukemia is affirmed as a distinct entity with unique pathologic, clinical, and immunobiologic characteristics. PMID- 6929660 TI - Management of a difficult airway in obstetrics. PMID- 6929658 TI - [Controlled ventilation in a patient with acute exacerbation of a chronic myeloic leucaemia. A case report (author's transl)]. AB - High counts of myeloid cells lead to erroneous results of blood gas measurements due to high rate of metabolism. This in vitro metabolism simulates hypoxaemia in the common chemical analyses. Therefore problems in the correct interpretation of blood gas measurements during controlled ventilation may arise, demonstrated in our case report of a patient with chronic myeloid leucaemia in acute stage. Immediate blocking of blood oxydative phosphorylation in the sample withdrawn is necessary in order to determine actual values which are important for adequate artificial ventilation. PMID- 6929659 TI - Hazards of hospital bulk oxygen delivery systems. AB - Numerous problems can occur with liquid oxygen delivery systems, in part because of the complexities of such systems. These systems must comply with guidelines of the Joint Commission on Accreditation of Hospitals. During the past year, 18 major problems with the liquid oxygen delivery system have occurred at the authors' hospital. Five times, false alarms have resulted from calibration drift in line pressure sensors. Thrice, excessive depletion of the reverse supply has occurred because of pressure imbalance between the main and reserve systems. Twice, excessive depletion of the reserve supply occurred owing to failure of the vacuum seal on the reserve supply vessel. Eight other potentially serious mishaps have also been reported. These problems, which are inherent in liquid oxygen delivery systems, are for the most part preventable. PMID- 6929661 TI - [ECG changes in patients during radiation therapy for osteogenic sarcoma under tourniquet hypoxia and anesthesia]. PMID- 6929662 TI - Radiotherapy and chemotherapy of limb tumours. AB - The place of radiotherapy and chemotherapy-separately, together, and in combination with surgery-in the treatment of limb tumours affecting skin, soft tissue, and bone is discussed. PMID- 6929663 TI - Cerebral vascular accidents after prophylactic central nervous system treatment during the course of acute lymphoblastic leukaemias and lymphomas. PMID- 6929666 TI - The importance of rapid, intraoperative histological diagnosis in the radical surgical treatment of the malignant tumours of the limbs. AB - During a period from 1971 to 1978 13 cases of limb tumours with suspected malignancy had a biopsy and depending on the result of histological examination of frozen sections a subsequent amputation in the same session. Material included 5 cases of osteogenic sarcoma, 3 cases of mesenchymal chondrosarcoma, 2 cases of synovial sarcoma and 3 tumours of other origin. In 11 cases the radical operation was performed in the same session and in 2 cases surgical intervention was delayed until after examination of the definitive sections. PMID- 6929664 TI - Infection during remission induction in childhood leukaemia. PMID- 6929665 TI - [Metastasized osteosarcoma with undifferentiated carcinoma-like parts]. AB - This was the case of a 64-year-old man with osteosarcoma. The biopsy yielded undifferentiated tumor without bone or cartilage formation. Because of high age of the patient and radiological changes present, a metastatic carcinoma was suspected. However, no primary could be found. Autopsy revealed an osteosarcoma in the region of the hip joint with alternating formation of tumor cartilage and tumor bone. There were also undifferentiated portions of "endocrine osteosarcoma," simulating carcinoma. In spite of extensive skeletal involvement and pulmonary metastases--and high age--no evidence of morbus Paget of bone as possible preneoplastic disease was found. PMID- 6929668 TI - Sudden infant death syndrome. PMID- 6929669 TI - A study of the use of serum protein electrophoretic patterns. PMID- 6929667 TI - [Skeletal muscles in myopathies]. PMID- 6929670 TI - The effects of body weight on serum cholesterol, serum triglycerides, serum urate and systolic blood pressure. AB - The effects of body weight and age on serum cholesterol, serum triglycerides, serum urate and systolic blood pressure were examined in 600 male and 400 female blood donors aged 20 to 49 years. In the men significant correlations with body mass index were found for all four variables in each decade. In the women below 40 only the correlation with blood pressure was significant. In the fifth decade the correlations resembled those in the men, save for triglycerides. After adjusting for weight, age had no independent influence on the prevalence of hypertriglyceridaemia or hypertension in either sex. In men the effect of body weight on the prevalence of hypercholesterolaemia was age dependent. Age influenced hyperuricaemia independently of weight. In women only serum cholesterol was affected by age after allowing for weight. There was marked clustering of high values of the four variables in the heavier men and women and this increased with age. The leanest men and women were remarkably free of high values. PMID- 6929671 TI - Acute intrahospital stroke mortality--an improving picture. AB - Case fatality ratios for the stroke syndrome are reported for patients admitted to two South Australian Teaching Hospitals during the period 1968--77. A fall in intrahospital acute phase stroke mortality was seen from 28.1% of stroke admissions in 1968--69 to 18.3% in 1976--77. Male stroke mortality rate fell from 28.1% to 17.0% and female mortality rate from 28.4% to 19.9% over this period. Changes in admission criteria and in duration of hospitalisation do not appear to account for this improvement in mortality figures. The age distribution of the total inpatient stroke population did not change significantly over this period. An increase in all hospital admissions of 46% over the period was paralleled in the stroke subgroup 15.5%. No improvement in therapeutic methods over the period in question appears to fully account for the improvement in mortality figures and it is inferred that these figures indicate an overall decrease in stroke severity on presentation. PMID- 6929672 TI - Heparin-associated thrombocytopenia: case report and prospective study. AB - After observing a patient with heparin-induced thrombocytopenia we prospectively recorded the incidence of thrombocytopenia associated with heparin treatment by measuring the platelet count every second day in 166 patients given therapeutic heparin for various thromboembolic disorders, and 51 patients given low-dose heparin prophylaxis. A platelet count below 100 x 10(9)/litre developed in nine patients (5.4%) during or soon after full-dose heparin therapy, and in one patient given low-dose heparin. Careful clinical review suggested that heparin was either the most likely cause of a contributing cause of thrombocytopenia in 5/166 patients (3.0%) receiving therapeutic heparin and none of the patients who received prophylactic heparin. Associated laboratory studies suggest that heparin initiated platelet aggregation in vivo is a useful marker for heparin-induced thrombocytopenia. PMID- 6929673 TI - 3,3' diiodothyronine: serum concentration and production in normal and abnormal thyroid states. PMID- 6929674 TI - Hepatitis A outbreak in a residential school. AB - Outbreaks of hepatitis A occurred sequentially in two wards for children in a residential institution for the mentally retarded in Sydney. Twenty-six of 41 children were initially susceptible to hepatitis A. In the first ward affected, 11 of 13 susceptible children (85%), and in the second ward, four of 13 susceptibles (31%), were infected. Of the 15 showing serological evidence of infection, five (33%) were clinically jaundiced. PMID- 6929675 TI - Renal infection with Mycobacterium chelonei. AB - A case of renal infection with Mycobacterium chelonei is described. The infection probably occurred via haematogenous spread from an infected arteriovenous shunt in a uraemic woman. Prolonged treatment with intravenous cefoxitin combined with oral erythromycin and rifampicin eradicated the organism from the urine. Although renal function stabilised for one year, gradual deterioration to end-stage renal failure occurred. PMID- 6929676 TI - Thrombotic thrombocytopaenic purpura and anuria: response to plasma exchange. AB - This report discusses the treatment and recovery of a 29-year-old woman with thrombotic thrombocytopaenic purpura complicated by servere renal failure. The case is reported because of the rarity of recovery from anuric renal failure in this disease and the probable contribution of plasma exchange to this recovery. PMID- 6929678 TI - Coronary artery spasm: use of ergonovine in diagnosis. AB - Ergonovine maleate was administered to 69 patients with chest pain but without significant coronary artery disease (less than 10% luminal diameter obstruction) to determine whether coronary artery spasm could be provoked. Coronary artery spasm was seen at angiography, or inferred from ECG or thallium myocardial perfusion scan changes. The test was positive in 16 patients: all five patients with documented variant angina (Group A); ten of the 19 patients with suspected variant angina (Group B); one of the 11 patients with exercise-induced chest pain (Group C); and none of the 34 patients with atypical chest pain (Group D). Patients with a positive test usually smoked, complained of recurrent nocturnal or early morning chest pain, showed ST changes during spontaneous chest pain and had minot degrees of fixed coronary obstruction (30--70%), when compared to those with a negative test. The only major side effect of the test was transient ventricular tachycardia which occurred in three patients and was reverted by sublingual and parenteral nitroglycerine. PMID- 6929679 TI - Lithium associated thyroid cancer. AB - This report documents papillary cell carcinoma of the thyroid occurring in a 55 year-old woman after three-and-a-half years of lithium therapy. She presented with unilateral thyroid enlargement causing tracheal deviation. There was no clinical suspicion of malignancy and the histological findings were totally unexpected. PMID- 6929677 TI - Dermal necrosis following coumarin: is it immunologically induced? AB - Two patients with dermal necrosis due to anticoagulation therapy with warfarin are reported. Both patients demonstrated some disturbance in immunological function. It appears possible that warfarin may act as a hapten in the induction of hypersensitivity to the drug. It is recommended that future cases should be studied to determine whether there is a defect in immunoregulation, and whether circulating immune complexes are responsible for the typical skin lesions. PMID- 6929680 TI - Coronary artery spasm. AB - Variant angina with ST elevation indicates transmural myocardial ischaemia and is due to spasm of a large epicardial coronary artery. Spasm occurs in arteries with varying degrees of fixed obstruction, giving rise to different clinical profiles of variant angina. However, coronary angiography is required to differentiate between those with minor coronary disease, and those with significant (greater than 70%) obstruction. In patients with minor coronary disease or normal arteries, beta-blockers are contraindicated, and treatment with calcium antagonist vasodilators should be commenced after documentation of spontaneous or ergonovine induced spasm. Patients with significant fixed coronary obstructions require bypass grafting if technically feasible. The role of coronary spasm is not confined to variant angina, as it causes angina at rest with ST depression, and may also cause myocardial infarction and sudden death. PMID- 6929681 TI - Behaviour pattern and coronary heart disease. PMID- 6929682 TI - Address by His Excellency Sir Zelman Cowen, A.K., G.C.M.G., K.St.J., Q.C. Governor-General of the Commonwealth of Australia at the Hilton Hotel, Melbourne, Wednesday, 10 may 1978, on the occasion of the opening of the Annual Scientific Meeting of The Royal Australasian College of Physicians. PMID- 6929685 TI - Early life [leter]. PMID- 6929686 TI - Higher training in dentistry. PMID- 6929683 TI - Legal and moral aspects of genetic engineering. PMID- 6929684 TI - Compartimentalization of spectrin-phosphorylating enzyme in human erythrocytes. PMID- 6929687 TI - A family history study of caries-resistance and caries-susceptibility. PMID- 6929689 TI - What has happened to descriptive clinical research? PMID- 6929690 TI - Alcoholic liver disease: what the practising clinician needs to know. PMID- 6929688 TI - Joint Committee for Higher Training in Dentistry. PMID- 6929692 TI - Comments on 'education and training' report by the Advisory Committee on Alcoholism to the DHSS and Welsh Office 1979. PMID- 6929691 TI - Solvent abuse by children and young adults: a review. PMID- 6929693 TI - Screening tests for alcoholism--findings from a community study. PMID- 6929694 TI - The behavioural measurement of dependence. PMID- 6929695 TI - Does sobriety and self-fulfilment always necessitate total and permanent abstinence? PMID- 6929698 TI - Consumption of cigarettes of reduced tar and nicotine delivery. PMID- 6929696 TI - A.A. ideology among alcohol treatment directors. PMID- 6929697 TI - There ought to be a law: research note on findings and limitations of survey research into general population attitudes about cannabis use, other deviancies, and the law. PMID- 6929699 TI - A variant form of hypergranular promyelocytic leukaemia (M3) PMID- 6929701 TI - Observations on human bone marrow granulocytic progenitor cell culture: a comparison of two ways to express results. PMID- 6929702 TI - Subclassification of acute lymphoblastic leukaemia in children: analysis of the reproducibility of morphological criteria and prognostic implications. AB - Stained smears of aspirated bone marrow obtained at time of diagnosis from 223 children with acute leukaemia were reviewed independently by three observers in a double-blind fashion in order to assess the reproducibility and clinical significance of the French-American-British Cooperative Group Classification. In 170 cases of acute lymphoblastic leukaemia (ALL), triple agreement of 69.4% was reached in the subclassification into L1, L2, and L3 types. The closest degree of agreement between two observers was 86.8%. In children with blasts classified as L1, 57 OF 61 patients (93.4%) remained in haematological remission after 12 months, as compared with 14 of 20 (70%) in children whose blasts were typed as L2 morphology, a difference which was statistically significant (P less than 0.05). There was no difference when these groups were compared after 24 or 36 months. Children older than 7 years had an increased incidence of L2 type (P less than 0.05). We conclude that although there may be significant variation in individual interpretations of the criteria utilized for classification, blast morphology may nevertheless be a useful prognostic factor. PMID- 6929700 TI - HLA haplotypes and long survival in childhood acute lymphoblastic leukaemia treated with transfer factor. AB - Association between HLA haplotypes and long survival was investigated in 116 children with acute lymphoblastic leukaemia. It was found that patients with A2 B12 and/or A2 B40 haplotypes survived longer than patients wtihout these two haplotypes. Since all children were treated with transfer factor obtained from their relatives, it is suggested that children possessing A2 B12 or A2 B40 haplotypes may respond better to this type of immunotherapy. PMID- 6929703 TI - Erythrocyte membrane modifications in chronic granulocytic leukaemia. PMID- 6929705 TI - Prognostic significance of lymphoblast morphology in acute lymphoblastic leukaemia (ALL) in childhood. PMID- 6929704 TI - Chronic myeloid leukaemia: evidence for basophil differentiation and histamine synthesis from cultured peripheral blood cells. AB - We have attempted to assess basophil differentiation in vitro in 15 patients with chronic myeloid leukaemia (CML). Using a sensitive radioassay, whole blood histamine values were found to be elevated in 10 of 14 patients tested, and correlated well with peripheral blood basophil counts (r=?70). In seven of nine CML patients, but not in controls, total histamine content of separated peripheral blood cells suspended in a modified Marbrook system was shown to rise after 7 d in vitro. Further study showed that both histamine (mean, five-fold increase) and basophils (mean, three-fold increase) were significantly elevated over control values at 1, 2 and 3 weeks in vitro. Total cell-associated histamine content (in pg per 100 viable cells) was greater in CML cultures than in controls at 3 weeks (P less than 0.01). Serial cultures of cells from one patient revealed substantial in vitro rises in basophils and histamine at an accelerated, but not at a chronic, phase of disease. Cells from this patient and two others studied at the time of blast crisis demonstrated higher indices of basophil and histamine increases when compared to the group of CML patients in chronic phases of the disease (P less than 0.05). We conclude that basophil precursors exist in increased numbers in the peripheral blood of CML patients. Assays for basophil differentiation may prove useful in following disease activity in this and other myeloproliferative disorders. PMID- 6929706 TI - Immunosuppression and serious infections in children with acute lymphoblastic leukaemia: a comparison of three chemotherapy regimes. AB - Eighty-four children presenting with acute lymphoblastic leukaemia were entered into a trial designed to test the effect on host toxicity of regular drug-free periods during chemotherapy. Patients received the same total dose of drugs either continuously (daily), intermittently (a 5 d course every 3 weeks) or in an intermediate way between these two (a 14 d course followed by a 7 d gap). Mean neutrophil counts were lower in the intermittent group and fell significantly at 6 week intervals, after courses which included prednisolone and vincristine in addition to methotrexate and 6-mercaptopurine. Mean lymphocyte counts, mitotic response to phytohaemagglutinin and plasma immunoglobulin levels were significantly lower in the continuous group. The results in the intermediate group fell between those of the other two groups. All six remission deaths occurred in the 42 patients in the continuous group, who had a much higher incidence of infections (mostly viral and protozoal) than the other two groups. It is concluded that the intermittent chemotherapy schedule permits the maintenance of a lymphocyte population size and function which provides a satisfactory level of defence against infection without prejudice to its anti leukaemic effect. PMID- 6929708 TI - [Attachment of nitrogenase to liposomes]. AB - The membrane has a stablizing effect on the nitrogenase complex, preventing its dissociation into separate enzymes and subunits. The distribution pattern of nitrogenase in artificial membranes and azotophores is similar. PMID- 6929707 TI - Studies on bovine adrenal estrogen sulfotransferase. V. Synthesis and assay of analogs of 3'-phosphoadenosine 5'-phosphosulfate as cosubstrates for estrogen sulfurylation. PMID- 6929709 TI - Familial imperative ideas and actions: how encoded? PMID- 6929710 TI - Measurement of estradiol-17 beta dehydrogenase activity in rat endometrium during the estrous cycle and the first half of pregnancy. PMID- 6929711 TI - Induction of rat endometrial estradiol-17 beta dehydrogenase activity by estradiol and progesterone. PMID- 6929712 TI - Interstitium: site of steroid synthesis in the ovary of the long term hypophysectomized hamster. PMID- 6929713 TI - Chronic myelocytic leukemia: eosinophils involved in the malignant clone. AB - Chronic myelocytic leukemia (CML) is a clonal disorder involving neutrophil, monocyte, erythrocyte, and platelet precursors. In order to determine if the eosinophils are also involved in the leukemic clone, we purified the eosinophils from a woman heterozygous for the common electrophoretic variants of the G6PD gene. Only type B enzyme was demonstrable in the eosinophils, neutrophils, and red cells, but both A and B enzymes were found in the fibroblasts. The data provide evidence that the eosinophil is involved in the malignant clone. PMID- 6929714 TI - Histiocytic lymphoma fifteen years following remission of acute lymphoblastic leukemia. AB - A 19-yr-old female presented with diffuse histiocytic lymphoma after a 15-yr remission of acute lymphoblastic leukemia. All treatment had been discontinued 7 yr before the onset of the lymphoma. The possible relationships of these two neoplasms are discussed. PMID- 6929715 TI - Crystalloid-containing giant granules in leukemic monoblasts. PMID- 6929716 TI - Suppression of normal granulopoiesis in vitro by a leukemia-associated inhibitor (LAI) of acute and chronic leukemia. PMID- 6929717 TI - Isolation of hybrid cell clones that contain deletion and non-deletion defects of alpha-thalassemia in man. AB - We have succeeded in isolating hybrid mouse erythroleukemia cell clones from a patient with hemoglobin H disease, which exhibit either deletion or nondeletion mutations of the human alpha-globin genes. Analysis of one of these hybrid clones that had retained a human chromosome 16 from the patient's cells showed that both human alpha-globin had been deleted. Several clones of another hybrid cell had retained a human chromsome 16 from the patient's cells, which contained both human alpha-globin genes on an EcoRI fragment of 23 kilobases (kb). These latter hybrid clones showed the presence of human alpha-globin chains at detectable but low levels. These studies show that there are two different types of human chromosome 16 in this patient and that the nondeletion mutation of human alpha globin genes leading to hemoglobin H diseases in this patient acts in cis to the two alpha-globin genes remaining in his cells. The close correlation between the pattern of human alpha-globin gene expression in the patient and in the hybrid cells suggests that this method of transfer of human globin genes to rodent cells will be a useful one for study of mutations affecting the expression of differentiated genes that lead to disease in man. PMID- 6929718 TI - Characterizing blood cells by biophysical measurements in flow. AB - One effect of automation in the hematology laboratory has been to introduce new characterizations of blood cells. Resistive pulse sensing (Coulter) and light scatter measurements in flow provide rapid and reproducible cell counts. They also provide information about red cell size, shape, and deformability. Thus, they have provided new characterization of these cells in terms of their biophysical properties. Leukocytes have been classified by optical scatter and absorption measurements in flow after being stained cytochemically. This provides rapid and precise WBC differential counts. However, here again, additional information about relative cell-enzyme content or activity is also accessible to provide a new characterization of the leukocytes. The ultimate range of utility of this expanding technology in the automated hematology laboratory of the future will, of course, depend upon establishing relations between the biophysical parameters and the functions of the cells. This, in turn, must depend upon the use of the technology by researchers and clinicians in studying cell function and the aberrations of these functions which define disease. PMID- 6929719 TI - Surgical training, quality surgical care, and informed consent. PMID- 6929720 TI - Legionnaires' disease in New York City, August-September 1978. PMID- 6929721 TI - Acute injuries of the anterior cruciate ligament of the knee: primary repair. PMID- 6929722 TI - Acute myeloblastic leukemia in elderly patients: treatment and prognostic factors. AB - The results of treatment of acute myeloblastic leukemia in patients over 60 years of age are evaluated in a retrospective study of 29 previously untreated patients. These results were very similar to those observed for younger patients, with 18 complete remissions (62, 1%), 6 early deaths, and 5 treatment failures. The median survival time was seven and one half months for all patients and 22 for the 18 patients achieving complete remissions. Nineteen patients received chemotherapy identical to that of younger patients (daunorubicin and cytarabine). The initial presence of poor prognostic factors (hyperleukocytosis, and infection) may explain the relativity high number of early deaths (21%). Elderly patients are apparently not exposed to a higher risk of death than younger patients. Daunorubicin toxicity does not appear to increase with age and this agent may therefore be used in the treatment of older patients. PMID- 6929723 TI - Burkitt's lymphoma presenting as acute leukemia (Burkitt's lymphoma cell leukemia): report of two cases in Israel. AB - Two rare cases of Burkitt's lymphoma presenting as acute leukemia are described. Both patients had typical features of Burkitt's lymphoma with rapidly growing, extranodal tumor masses which were multifocal. The blasts infiltrating the bone marrow and peripheral blood showed cytologic, cytochemical, immunologic, and ultrastructural features of Burkitt's tumor cells. The cells had B-cell markers but lacked the EBV-DNA genome and had multiple microvilli as seen by means of scanning electron microscopy. In both cases, the disease was resistant to chemotherapy and rapidly fatal, despite the fact that complete remissions of short duration was obtained. PMID- 6929726 TI - Amygdalin (Laetrile): effect on clonogenic cells from human myeloid leukemia cell lines and normal human marrow. AB - The effect of amygdalin on human acute myelogenous leukemia cells and normal bone marrow granulocyte-monocyte precursors was studied in vitro using soft-gel culture. A pharmaceutical and a clinical source of amygdalin were tested and beta glucosidase was added to selected cultures to promote the hydrolysis of amygdalin. Acute myelogenous leukemia cells were obtained from two human cell lines designated KG-1 and HL-60. A 50% inhibition of colony formation by both normal and leukemic cells was observed at an amygdalin concentration of 3.5 mg/ml using both drug sources. We found the colony-forming cells from the leukemic cell lines and normal marrow to be relatively resistant to amygdalin and its metabolites in vitro, and there was no selective kill of clonogenic cells from the human leukemia cell lines as compared to normal bone marrow. PMID- 6929725 TI - Heterotransplantation and clonal growth of human Ph'-chromosome-positive leukemia cell (NALM-1) and B-cell leukemia-cell (BALM-2) lines. AB - Human hematopoietic cell lines, NALM-1, derived from Ph'-chromosome-positive chronic myelocytic leukemia (CML) in blastic crisis, and BALM-2, derived from B cell acute lymphoblastic leukemia (ALL), were tested for their heterotransplantability and clonability. Two previously established cell lines, a Burkitt's lymphoma cell line, B35M, and a B-lymphoblastoid cell line, B411-4, derived from a hematologically normal person, were used for comparison. Ten million cells were needed in order for the BALM-2 cell line to grow with 74% success in the immunosuppressed mice, but 1000 million cells were needed in order for the NALM-1 cell line to grow with 74% success in those mice. As in the case of the BALM-2 line, 10 million cells of the B35M cell line were needed for 100% success in heterotransplantation, whereas 30 million cells of the B411-4 cell line resulted in 20% success of heterotransplantation. In a semisolid agarose (0.15%) medium, the cloning efficiencies of BALM-2, B35M, and B411-4 were 1.52- 2.08, 26.31--38.46, and 0.09--0.12, respectively. With as many as 25,000 cells per well plated, NALM-1 did not produce any colonies in the semisolid agarose medium. Unlike most previous findings, those of the present study suggest that the heterotransplantability and clonability of cultured cells may not be invariably reliable characteristics of all proven human leukemia-lymphoma cell lines. The behavior of these leukemia cell lines representing their respective original leukemia clones is interpreted as reflecting the heterogeneity inherent in the biologic characteristics seen in human leukemias. PMID- 6929724 TI - Computed tomography brain scans in children with acute lymphocytic leukemia receiving methotrexate alone as central nervous system prophylaxis. AB - Central nervous system (CNS) "prophylaxis" is critical in the treatment of acute lymphocytic leukemia (ALL). The standard method employed combines cranial radiation (CRT) and intrathecal methotrexate (IT MTX). Recently, a 52% incidence of abnormal computed tomography (CT) brain scans was found in asymptomatic children with ALL whose CNS prophylaxis consisted of CRT and either IT MTX or intrathecal cytosine arabinoside (IT Ara-C). In the present study, CT brain scans were studied in 43 asymptomatic children with ALL in continuous complete remission. The CNS prophylaxis consisted of IT MTX alone in 10 patients and IT MTX combined with intermediate-dose intravenous MTX in 33 patients. No patient had received CRT. The patients' ages at the time of diagnosis ranged from 22 months to 17 years, 7 months. The time interval from completion of CNS prophylaxis to CT scanning ranged from ten to 59 months. Only one CT scan was clearly abnormal; it showed mildly dilated ventricles and visualization of the cortical sulci. The CT scans of 7 additional patients were classified as abnormal because of borderline dilatation of the lateral ventricles (3 patients) and/or visualization of the cortical sulci (7 patients). No patient demonstrated areas of decreased cerebral attenuation coefficient or intracerebral calcification- findings previously ascribed to the use of methotrexate. Clinical leukoencephalopathy has not been observed in any of our patients. This would suggest that MTX alone in the absence of CNS leukemia or CRT is highly unlikely to produce structural CNS abnormalities detectable by CT. PMID- 6929727 TI - Antitumor activity of benzaldehyde. AB - Ninety patients with inoperable carcinoma in the terminal stages and 12 patients in serious condition with other tumor types were given benzaldehyde in the form of beta-cyclodextrin benzaldehyde inclusion compound (CDBA) orally or rectally at a daily dose of 10 mg/kg divided in four doses. Toxic effects, including hematologic or biochemical disturbances, were not seen during long-term successive administration of CDBA. Fifty-seven of the patients treated were evaluable; 19 patients responded completely and ten patients responded partially (greater than 50% regression). For all responding patients longer response durations were associated with longer CDBA treatment periods. Treatment of squamous cell carcinoma induced the cancer cells to change into a conglomeration of pearls (the well-known product of differentiation) which consisted of keratinized normal squamous cells. PMID- 6929728 TI - Initial clinical study with vindesine: tolerance to weekly iv bolus and 24-hour infusion. AB - Forty-six patients with inoperable cancer and leukemia in relapse were given vindesine (VDS) either by iv bolus weekly at doses ranging from 2.0 to 5.5 mg/m2 or by 24-hour continuous infusion weekly at doses ranging from 1.0 to 7.0 mg/m2 of estimated body surface area. VDS was well-tolerated by patients with normal liver function who had previously been minimally treated with myelosuppressive agents at a dose of less than or equal to 4 mg/m2 either by iv bolus or by 24 hour infusion weekly. The dose-limiting toxic effects of VDS were leukopenia and neurotoxicity. Leukopenia was cumulative but easily reversible by interruption of weekly dose. Neurotoxicity was insidious and hardly reversible. Patients with liver dysfunction appeared to develop more neurotoxicity. Other toxic effects included a decrease in hemoglobin level, transient hepatic dysfunction, cellulitis or phlebitis at the iv site, stomatitis, nausea, and vomiting. Degrees and parameters of toxic effects observed after iv bolus and 24-hour infusion of the same doses were indistinguishable except for an increased incidence of local cellulitis in the infusion group. PMID- 6929730 TI - Lesion depth and microhardness indentations on artificial white spot lesions. PMID- 6929729 TI - Plasma fluoride concentration and urinary fluoride excretion in children following application of the fluoride-containing varnish Duraphat. PMID- 6929732 TI - A method for simulatneous measurement of calcium and phosphorus in tooth surface samples, dissolved in vivo, using activation analysis. PMID- 6929731 TI - Influence of fluoride in surface enamel and degree of dental fluorosis on caries development in vitro. PMID- 6929734 TI - Use of high-performance liquid chromatography techniques to study the protection of hydroxylapatite by fluoride and glycerophosphate against demineralization in vitro. PMID- 6929735 TI - Plasma alkaline phosphatase levels in subjects taking fluoride tablets. PMID- 6929733 TI - Chemical studies of the protective action of phosphate compounds against the demineralization of human dental enamel in vitro. PMID- 6929736 TI - [Osteogenic sarcoma of the breast]. AB - A ball-shaped lump, 6 cm in diameter, showing the structure of extraosseous osteogenic sarcoma, was removed from the left breast of a 59 year old woman. This extremely rare breast tumour was seen developing indepedently, i. e. enconnected with any other epithelial, mesenchymal or mixed tumour as is more often the case. It is usually included in the group of stromal sarcomas of the breast. In addition, there was also dysplasia and a small focus of lobular carcinomas in the mammary gland. PMID- 6929737 TI - [Causes of the development of orthodontic anomalies in patients with a total unilateral cleft]. PMID- 6929738 TI - [The etiology of diastemas]. PMID- 6929739 TI - [Evaluation of the results of fenestration of the lower vestibule in the treatment of periodontal diseases]. PMID- 6929740 TI - [Proprioception of the human tongue. Methods and observations]. PMID- 6929741 TI - [Calcified odontogenic cyst]. PMID- 6929742 TI - [Microcirculation of the marginal gingiva and current problems and prognosis in the study of peridontal microcirculation in the near future]. PMID- 6929744 TI - [Long-term results in the treatment of root canals with calcium hydroxide]. PMID- 6929743 TI - [The development of the periosteum of the human mandible in the 1st months of intrauterine life]. PMID- 6929747 TI - Solubilized bone morphogenetic protein (BMP) from mouse osteosarcoma and rat demineralized bone matrix. AB - A selection of proteins including bone morphogenetic protein (BMP) was extracted in a disaggregated form from Dunn osteosarcoma or rat demineralized bone matrix by 4M guanidine hydrochloride (GuHCl) solution without losing its biological activity. The GuHCl extracts of Dunn osteosarcoma were divied into 4 different fractions by cesium chloride (CsCl) density gradients. Under a dissociative condition, the highest new bone yield was obtained in the low dense top one-third fraction, and BMP acitivity declined with increase in the density of each fraction. No BMP potential was observed in the surface-gel fraction under dissociative conditions. Under an associative condition (low GuHCl concentrations), BMP activity appears in the surface-gel fraction, while under a dissociative condition (high concentrations of GuHCl) BMP appears in the fraction below the surface gel. These facts suggest that under associative conditions, BMP aggregates with other low dense proteins in the surface-gel fraction and that this may be the state of aggregation of BMP in cells and matrix in nature. Present observations support the assumption that BMP is a relatively low density protein and excludes the idea of BMP activity in the collagen molecule, per se. A specific protein, with an apparent molecular weight of 63,000 daltons, is present in all fractions that exhibit BMP activity, and absent in fractions that do not exhibit this activity. BMP is not species-specific; rat BMP induces bone formation in mice. CsCl density-gradient centrifugation is an efficient tool for further purification and isolation of BMP. PMID- 6929746 TI - Acute myelogenous leukemia heteroantisera. PMID- 6929745 TI - DNA nucleotidylexotransferase of normal persons and leukemic patients. AB - We describe a relatively simple and rapid assay for DNA nucleotidylexotransferase (EC 2.7.7.31) activity in normal lymphocytes and leukemic cells from blood and (or) bone marrow of patients with various types of leukemia. We followed the method of Beutler and Kuhl (Am. J. Clin. Pathol. 70: 733, 1978) but separated the product of the reaction by precipitation on filter-paper disks instead of by centrifugation. Normal lymphocytes had a mean activity of 13.5 (SD = 9.21; range 3 to 35) pU/10(8) cells. Leukemic cells from the peripheral blood of patients with acute myelogenous leukemia had a mean activity slightly greater than normal (48 pU/10(8) cells); those from patients with acute lymphoblastic leukemia had a mean activity of 863 pU/10(8) cells, or 62-fold the normal mean. Similarly, cells from patients with chronic myelogenous leukemia in acute phase had a normal activity when the cell proliferation was myelogenous, but much higher activities when the cell proliferation was lymphoblastic. Cells from patients with chronic lymphocytic leukemia had normal activity. In leukemic patients, approximately similar results were obtained with cells isolated from bone marrow. PMID- 6929748 TI - [A sporadic case of hereditary sensory neuropathy with tonic pupil, ichthyosis vulgaris, deafness and atypical retinitis pigmentosa (author's transl)]. PMID- 6929749 TI - Deleterious effects of drugs used for hyperactivity on patients with Gilles de la Tourette syndrome. AB - Two pediatricians failed to recognize Gilles de la Tourette syndrome in a child. The symptoms were exacerbated after the child took both pemoline and methylphenidate. All medications commonly used to treat hyperactivity may cause such exacerbation. Gilles de la Tourette syndrome is frequently associated with symptoms characteristic of hyperactivity and often goes unrecognized for long periods of time. The symptoms of the syndrome and the evidence that they are exacerbated by medication used to hyperactivity are briefly reviewed. Physicians should be aware of the possibility of Gilles de la Tourette syndrome in any hyperactive patient who manifests or has a history of a tic. PMID- 6929750 TI - [Change in the outline of the distal femoral metaphysis simulating osteosarcoma]. PMID- 6929751 TI - Effect of thyroid hormones on the 3-oxo acid CoA-transferase activity in rat brain during development. AB - The changes in the developmental pattern of 3-oxo acid CoA-transferase activity in the brain of hypothyroid rats and the effect of triiodothyronine on this enzyme activity have been investigated. Hypothyroid rats showed lower activity than controls during the suckling period. However, higher enzyme levels were found in treated rats after weaning in contrast to control animals. The results suggest that thyroid hormones promote the development of enzymes of ketone-body metabolism in the brain. PMID- 6929752 TI - Defects in enzyme regulation versus defects in enzyme synthesis as cause of metabolic disorders. AB - Based on the consideration that normal metabolic processes depend upon the activity of key enzymes (and membrane carriers) as modulated by regulatory factors (hormones, diet, endogenous compounds, age, physical activity, environmental agents), metabolic disorders might be classified into two groups: (I) defects in enzyme synthesis, leading to enzyme deficiency (classical inborn errors of metabolism) or to qualitative (structural) enzyme alterations (entailing unresponsiveness to regulation), in the presence of normal regulatory factors; (II) defects in enzyme regulation, which include metabolic syndromes such as diabetes mellitus, obesity and hyperlipoproteinemias (other than type I), and are due to changes in enzyme activities caused by alterations in regulatory factor(s) (secondary to various causes), in the presence of normally responsive enzymes. PMID- 6929753 TI - Effect of cyproterone acetate on the testis and epididymis of the lizard, Psammophilus dorsalis (gray). AB - The effect of cytproterone acetate (CPA) on the testis and epididymis of the lizard, Psammophilus dorsalis has been studied. Treatment with CPA affects spermatogensis and steroid metabolism in the testis. It also causes regression of the epididymis and a decrease in steroidogenic enzyme activity. PMID- 6929754 TI - [The Nitinol arch wire]. PMID- 6929755 TI - [The role of parotid saliva analysis in the differential diagnosis of non tumorous parotid swellings]. PMID- 6929756 TI - [The effect of rinsing with various sugar solutions on the osmotic pressure of saliva]. PMID- 6929757 TI - [Fausse route]. PMID- 6929758 TI - [Measuring the relative duration of effect of local anesthetics]. PMID- 6929759 TI - [The effect of high doses of NaF on the metabolism of rats]. PMID- 6929760 TI - [Reimplantation of upper incisors]. PMID- 6929762 TI - Diagnostic radiographic aspects in endodontics. PMID- 6929761 TI - [Isosit, a new composite dental material]. PMID- 6929763 TI - The external fistula: its diagnostic importance. PMID- 6929764 TI - An unusual incisive canal. PMID- 6929766 TI - Healed calcified tubercular lesion. PMID- 6929765 TI - Inverted mesiodens. PMID- 6929767 TI - Properdin factor B(Bf) allele BfF1 specifies an HLA-B18 diabetogenic haplotype. AB - We found the rare properdin factor B(Bf) variant F1 to be present in 11% of 72 patients suffering from insulin-dependent diabetes (IDDM) compared with 2% among 150 normal controls. BfF1 thus confers a relative risk for IDDM of 5.55. All eight patients and three controls who were BfF1 positive were also HLA-B18 positive, reflecting the strong linkage disequilibrium between these two factors. We suggest that BfF1 marks a 'diabetogenic' B18-bearing HLA haplotype. Studies of unselected families with one or more affected members suggest that the B18, BfF1 does not necessarily segregate with IDDM phenotype. This study provides further evidence for the genetic heterogeneity of IDDM. PMID- 6929768 TI - Raised lead levels and impaired cognitive/behavioural functioning: a review of the evidence. AB - Research findings on the effects of raised lead levels on children's cognitive and behavioural functioning are reviewed. The results are considered separately with respect to clinic-type studies of children with high lead levels, studies of mentally retarded or behaviourally deviant children, chelation studies, smelter studies, and general population studies of dental lead. It is concluded that, although the findings are somewhat contradictory, the evidence suggests that persistently raised blood levels in the range above 40 microgram/100 ml may cause slight cognitive impairment (a reduction of one to five points on average) and less certainly may increase the risk of behavioural difficulties. There are pointers that there may also be psychological risks with lead levels below 40 microgram/100 ml, but the evidence on this point is inconclusive so far. Parallels are drawn with studies of other brain traumata and some suggestions are made with respect to both practical implications and the needs for further research. PMID- 6929769 TI - Induction by chloroquine of differentiation of cultured mouse myeloid leukemia cells. AB - The effect of chloroquine on differentiation of cultured mouse myeloid leukemia Ml cells was examined. On treatment with 5 approximately 25 microgram/ml of chloroquine diphosphate for 1 approximately 4 days, the cells were induced to phagocytize latex beads, to form Fc rosettes, to form dispersed colonies in soft agar, and to synthesize lysozyme, unlike untreated cells. The morphology of about 40% of the cells changed during treatment with 20 microgram/ml of chloroquine diphosphate for 4 days; some cells developed small eccentrically located nuclei, and others ring-shaped or segmented nuclei. These results show that Ml cells differentiate into cells resembling macrophages or granulocytes on treatment with chloroquine. PMID- 6929771 TI - Hypnosis as an "entree" for consultation-liaison psychiatry. AB - In addition to its indicated uses, hypnosis can play another important, more indirect role in consultation-liaison psychiatry. It can serve the consulting psychiatrist as an entree to physicians or who have rejected traditional psychiatric help. Four case studies which illustrate this point are presented and discussed. PMID- 6929770 TI - Potentiation of therapeutic effects of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl] 1-(2-chloroethyl)-1-nitrosourea hydrochloride by 6-thioguanine in mouse tumor systems: comparison with other antimetabolites. AB - Antitumor activities of a combination chemotherapy with a water-soluble nitrosourea, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1 nitrosourea hydrochloride (ACNU), and a single dose of 6-thioguanine were studied using three obstinate murine tumor systems, i.e., Lewis lung carcinoma, B16 melanoma, and an advanced stage of L1210 leukemia systems. Therapeutically synergistic effect was observed either definitely against 1- or 2-day-old Lewis lung carcinoma and 6-day-old L1210 leukemia or moderately against 1-day-old B16 melanoma. Single intravenous treatment on day 7 after subcutaneous implantation of Lewis lung carcinoma, when the tumors had already metastasized to the lungs, produced a significant regression of tumor and a significant increment in survival time of tumor-bearing mice. In comparative studies, the combination of ACNU and 6-thioguanine showed a greater and a wider spectrum of antitumor activities against these tumors than those obtained by the combination with ACNU and a single dose of 5-fluorouracil, methotrexate, or 6-mercaptopurine. Increment in lethal toxicity for normal and tumor-bearing mice was not observed by the combination of ACNU and 6-thioguanine in contrast to definite increases in this toxicity by the combination of ACNU and 5-fluorouracil. The present experimental results may suggest the clinical utility of the combination chemotherapy with ACNU and 6-thioguanine in the treatment of several solid tumors as well as acute leukemias. PMID- 6929772 TI - Symbiotic dinitrogen fixation as affected by short-term application of nitrate to nodulated Pisum sativum L. AB - Effect of nitrate on the nitrogenase (C2H2-reduction) activity, growth of nodule tissue accumulation of nitrate and nitrate reductase activity in 4-weeks-old nodulated peas (Pisum sativum L.) was investigated. A relatively slow decrease of the total nitrogenase activity (mumol C2H4 per root per h), as compared with plants cultivated without nitrate, was due to both retardation of further growth of the nodule tissue and to a decrease of their specific nitrogenase activity (mumol C2H4 per gf.wt. per h). However, an absolute and pronounced decrease of both nitrogenase activities occurred only 4 or 7 d after the application of nitrate. The addition of nitrate led to its rapid accumulation in the nodule and leaf tissue with a simultaneous induction of the nitrate reductase activity. The nitrogenase activity was not completely inhibited even after a 7-d cultivation with 280 m NO3- -N in the nutrient medium and after accumulation of up to 180 ppm NO3- -Nf.wt. in the nodule tissue. The results obtained indicate that the "photosynthate deprivation" reflects competition between assimilation of nitrate and fixation of dinitrogen. PMID- 6929773 TI - Prognosis in diabetic autonomic neuropathy. PMID- 6929775 TI - Nerve biopsy and conduction velocity along the sural nerve in diabetic neuropathy. PMID- 6929774 TI - Morphology of diabetic neuropathy. PMID- 6929777 TI - Vascular and coagulation abnormalities in diabetic neuropathy and encephalopathy. PMID- 6929776 TI - Sural nerve conduction velocity and refractory period in diabetics without clinical signs of neuropathy. AB - Twentysix patients aged 22-76 years with a duration of diabetes of 1 month to 23 years but without signs of symptoms of a peripheral nerve disease were studied. The nerve conduction velocity, the amplitude of the compound action potential and its restitution during the relative refractory period were examined in sural nerves. Nerve conduction velocity of the motor fibers were determined in the median, ulnar, tibial, and peroneal nerves. A reduced conduction velocity in motor nerves of the lower extremities were found in 10%, a reduced sensory nerve conduction velocity in 25%, and pathological changes of the refractory period in 50% of the patients. It is concluded that the determination of the relative refractory period can be used as a sensitive test in the early diagnosis of diabetic neuropathy. PMID- 6929778 TI - Clinical features of diabetic autonomic neuropathy. PMID- 6929779 TI - Tests of cardiovascular reflex function in diabetic autonomic neuropathy. PMID- 6929781 TI - Studies of heart rate oscillations in diabetics at rest. AB - Variation in electrocardiographic R-R intervals during rest was investigated as a measure of autonomic function and as a diagnostic tool in diabetes. Diabetics (106) of both sexes with different duration of the disease were compared with 116 metabolically healthy control subjects of the same age range. Diabetic retinopathy was diagnosed using fundus photography, and classified in stages O II. Coefficient of variation (CV) of R-R intervals in controls is age-dependent. The negative correlation between CV and age in diabetics applied only when retinopathy was absent; in diabetics with late complications, CV was significantly lower (p less than 0.0001) than in the healthy or in uncomplicated diabetic state. The CV decreased with increasing severity of retinopathy permitting routine differentiation of progressive stages of retinopathy and peripheral neuropathy. PMID- 6929782 TI - Investigations of autonomic diabetic neuropathy of the cardiovascular system. AB - One-hundred and nine patients consecutively admitted to our hospital underwent a standardized sustained hand grip test, the Valsalva maneuver, and the Schellong test in a study of autonomic diabetic neuropathy of the cardiovascular system. The correlation between autonomic diabetic neuropathy of the cardiovascular system and the duration of diabetes, the age of the diabetic patient, the forms of treatment, and other neuropathic or vascular complications of diabetes was studied. Autonomic diabetic neuropathy of the cardiovascular system is a complication of long-term insulin-dependent diabetes and is dependent on the duration of the disease. The responses to the Valsalva maneuver in 17 poorly controlled diabetics before and after establishing good control of the diabetes showed no change in the Valsalva ratio. Short-term changes in diabetic control seem to have no effect on the Valsalva ratio as an indicator of autonomous nervous system involvement. The so-called "10 second Valsalva ratio" is a simple and reproducible method of evaluating the Valsalva maneuver. PMID- 6929780 TI - Assessment of diabetic autonomic neuropathy using heart rate monitoring. AB - Heart rate (HR) monitoring has been used for the diagnosis of diabetic autonomic neuropathy (AN). Two tests were used: measurement of heart rate variation (HRV) during deep breathing and measurement of HR changes on standing up. Three-hundred and one diabetics between 20 and 49 years old were studied, and 21 of them were observed repeatedly over 3-5 years. HRV on deep breathing was the most sensitive diagnostic test of AN, and was abnormal in 84% of 64 patients with established autonomic symptoms. Autonomic abnormalities were also detected in diabetics without autonomic symptoms, especially those with peripheral neuropathy. Abnormal tests represent permanent autonomic damage and may be present for several years before the development of autonomic symptoms. Occasionally they represent the earliest manifestation of diabetic neuropathy. PMID- 6929783 TI - Glucagon response to hypoglycemia in diabetic neuropathy. AB - Glucagon release during insulin hypoglycemia was studied in diabetics with autonomic neuropathy (N = 9), diabetics without clinical neuropathy (N =8), and normals (N = 9). With similar hypoglycemic stimulus, growth hormone and plasma cortisol increased in all groups. Plasma glucagon increased threefold in normals (121 +/- 19 vs. 308 +/- 30 pg/ml., mean +/- SEM of baseline vs. hypoglycemic peak) and twofold in nonneuropathic diabetics (128 +/- 13 vs. 209 +/- 30). There was no glucagon rise during hypoglycemia in the neuropathic diabetics (128 +/- 23 vs. 115 +/- 20). Arginine infusion produced glucagon rise in the neuropathic diabetics (106 +/- 16 vs. 523 +/- 103). The study suggests that failure to release glucagon during hypoglycemia is due to diabetic neuropathy. Neuropathy may contribute to metabolic instability. PMID- 6929784 TI - Plasma catecholamines in long-term diabetes. AB - To investigate a possible defect in sympathetic innervation of the blood vessels in diabetics, 18 normals, 13 normotensive juvenile diabetics without complications and 13 normotensive juvenile diabetics with complications were first treated with an increasing infusion of norepinephrine (NE) and subsequently given a two minutes' exercise with a 150 Watt load. Plasma catecholamines were measured under both conditions. In the infusion experiments diabetics were found to have higher NE levels than normals. In normals NE fells to starting levels 5 min. after completion of the work load. In diabetics this fall-back rate was slower. The reduction in the fall-back rate was correlated with the duration of the diabetes. PMID- 6929785 TI - The natural course of diabetic neuropathy. A follow-up. AB - Out of an unselected group of 160 patients with diabetic neuropathy 51 patients were followed up for an average of 5, 6 years by repeated neurological examinations and by means of a questionnaire. The control of the diabetes was requested from the house physicians. The patients were classified as presenting (1) a symmetrical, predominantly sensory neuropathy (2) a mixed syndrome with additional autonomic neuropathy and (3) multiple mononeuropathy. Individual symptoms and objective signs of neuropathy revealed a remarkable variety of changes. The outlook in multiple mononeuropathy and distal paresis was favorable while autonomic failures, in particular of male sexual function, progressed. There seemed to be some beneficial effect of improved glycemic control. However, despite satisfactory metabolic control some progression of diabetic neuropathy occured. PMID- 6929786 TI - Aberrations of chromosome No. 1 in blastic phase of chronic myeloid leukemia. PMID- 6929788 TI - Clinical observations on telekinesis. PMID- 6929789 TI - Hypnosis and free will. PMID- 6929787 TI - [Pharyngeal abscesses following tonsillectomy (author's transl)]. AB - A few weeks after tonsillectomy two patients presented with recurring pharyngeal abscesses, and a fistula and a cyst were identified as the probable reasons for these. The embryology and differential diagnosis is discussed. The Grisel Syndrome and its presentation following tonsil remnant infection is demonstrated in another patient. PMID- 6929790 TI - Hypnosis--living--comfort. PMID- 6929791 TI - Cigarette smoking, oral hygiene and periodontal health in Swedish army conscripts. AB - Possible dissimilarities between smokers and nonsmokers regarding oral hygiene, gingivitis, periodontal pocketing and alveolar bone loss were studied in a sample of 134 army conscripts. Compared to nonsmokers, smokers had a higher plaque index and greater severity of gingivitis, while no differences were found concerning pocket depth and bone loss. It could be demonstrated that the difference regarding gingivitis disappeared when a check was made for plaque values. It still remains to be explained why plaque deposition is more pronounced in smokers. PMID- 6929792 TI - Influence of overhanging posterior tooth restorations on alveolar bone height in adults. AB - The aim of this radiographic investigation was to compare the approximal bone height adjacent to class II amalgam restorations with and without overhangs to the bone height adjacent to homologue intact tooth surfaces, and to determine the possible effect of age and sex on the relative amount of such bone resorption. The x-rays of 43 persons aged 27--45 years and 42 persons aged 46--64 years were examined. In the total material the average amount of bone loss increased with age and was 0.34 mm greater in men than in women. About 50% of all posterior tooth restorations had an overhang. A comparison between the mean heights of approximal bone adjacent to sufaces with an overhang and homologue intact surfaces showed a statistically significant difference. When equal comparisons were made separately in the younger and the older age groups, only the older group showed a similar difference at a statistically almost significant level. The effect of overhanging restorations thus seemed to be accentuated with age. When men and women were studied separately, only men showed statistically significant differences between the age groups. The investigation confirms earlier results that overhanging posterior restorations are associated with excessive marginal approximal bone loss. PMID- 6929793 TI - Plaque removal by various triangular toothpicks. PMID- 6929794 TI - The furcation problem. Etiology, pathogenesis, diagnosis, therapy and prognosis. PMID- 6929796 TI - Self-control in the treatment of Gilles de la Tourette's syndrome: case study with 18-month follow-up. PMID- 6929795 TI - Healing following implantation of periodontitis affected roots into bone tissue. AB - The aim of the present experiment was to study whether new connective tissue attachment can occur to root surfaces which have been exposed to the oral environment and subsequently implanted into bone tissue. Twelve teeth in three beagle dogs were subjected to progressive periodontal breakdown to half the root length by placing cotton floss ligatures around the neck of the teeth. Following crown resection and root hemisection, the teeth were root filled and the roots thoroughly scaled and planed. Each root was extracted and implanted into bone cavities prepared in edentolous areas of the jaws in such a way that epithelial migration into the wound and bacterial infection were prevented during healing. Root implantation and sacrifice of the animals were scheduled to allow for observation periods of 1, 2 and 3 months. The results demonstrated that new connective tissue attachment did not occur to root surfaces which had been exposed to the oral environment, but healing was characterized by repair phenomena, i.e. mainly root resorption and ankylosis. In those areas of the roots where periodontal ligament tissue was preserved following tooth extraction, a functionally oriented attachment apparatus was reformed. The results indicate that in addition to apical migration of junctional epithelium and regrowth of subgingival plaque, the type of cells which repopulate the wound area may jeopardize new connective tissue attachment. PMID- 6929797 TI - Trauma in the primary dentition: a clinical presentation. PMID- 6929799 TI - Genetic aspects of shell teeth: report of case. PMID- 6929798 TI - Dentin radiolucencies in unerupted teeth: report of two cases. PMID- 6929801 TI - Ectodermal dysplasia: report of two female cases. PMID- 6929802 TI - Idiopathic multiple internal resorption: report of case. PMID- 6929804 TI - Dental care. PMID- 6929800 TI - Coeliac disease and dental malformation. PMID- 6929803 TI - Guidelines for national nutrition policy. PMID- 6929805 TI - The inter-examiner variation in rating dental formation from radiographs. AB - Six examiners evaluated dental formation on 191 radiographs, using an eight-stage system. Discrepancies between these examiners are generally of the order of +/- one stage, in about 20 to 25% of the cases. The authors thus suggest the use of reference radiographs, for the double purpose of ensuring a homogeneous rating by two examiners or more, as well as the assessment of eventual differences between populations. PMID- 6929806 TI - Amalgam surfaces polished with a vibrator. AB - Vibratory polishing is shown to be a method for preparing amalgam specimens for microscopic examination of grain structure without chemical etches. The paper describes the optimum parameters for six amalgams and 14 abrasives under varying loads and polishing times. PMID- 6929809 TI - Apparent viscosities of setting elastomers. AB - The flow behavior of five elastomeric impression materials was determined by extrusion viscometry. Initial viscosity ranged from 400 to 5,100 poise at a shear rate of 2.2 reciprocal seconds. All of the elastomers showed initial non Newtonian behavior and increased viscosity with time. PMID- 6929808 TI - Physical properties of a pigmented silicone maxillofacial material as a function of accelerated aging. AB - The effects of accelerated aging on a pigmented elastomer were evaluated by using a weathering chamber. Silastic 44210, a maxillofacial material with proven color and physical property stability, was chosen for pigmentation with 11 maxillofacial pigments. The values of ultimate tensile strength, maximum percent elongation, shear strength, Shore A hardness, and permanent deformation were determined for the pigmented elastomer before and after accelerated aging for 900 h. Results obtained indicate that the incorporation of 0.2% by weight of pigments can alter the physical and mechanical properties of the base elastomer. Accelerated aging had no effect on the physical properties of the pigment/elastomer combinations. PMID- 6929807 TI - Estimation of radiation dose from porcelain teeth containing uranium compound. AB - Uranium concentrations of porcelain teeth were determined using the fission track method. The uranium contents of each brand range 0.33-10 ppm, 0.69-81 ppm, 2.5-14 ppm, and 11-205 ppm, respectively. In addition, corresponding dose equivalents to the oral mucosa were calculated. PMID- 6929811 TI - Casting accuracy of nickel-chromium alloys: marginal discrepancies. PMID- 6929810 TI - Linear dimensional changes in elastic impression materials. AB - Four classes of elastomeric impression materials (polysulfide, polyether, silicone, and agar-agar) were evaluated on the basis of linear dimensional stability as a function of time between taking and pouring an impression of mounted teeth. Four polysulfide materials produced dies which were larger than the teeth and generally increased in size with impression storage time. One silicone material produced dies slightly smaller than the teeth, and the dies from another silicone were dramatically smaller with increasing storage times. A polyether material produced slightly smaller dies for up to four hours' storage time, then increasingly larger dies up to 24 h. The dies from a reversible hydrocolloid were larger than the teeth for storage times up to 30 min, and then decreased rapidly at longer times. PMID- 6929812 TI - Development of multisurface caries in adolescent rats. PMID- 6929813 TI - An exception to the apparent relationship between stress and fluctuating dental asymmetry. PMID- 6929814 TI - Properties of malate dehydrogenase isozymes in rabbit dental pulp. PMID- 6929815 TI - Radiofluoride distribution in rat lung, colon, and heart. PMID- 6929816 TI - The effect of galvanic corrosion on the axial tensile strength of amalgam. PMID- 6929817 TI - Effects of topical hydrogen peroxide on caries incidence and bacterial agglomerate formation in rats. PMID- 6929818 TI - Comparison of glucose-induced plaque pH changes after one year. PMID- 6929819 TI - Cariogenic potential of Bifidobacterium in gnotobiotic rats. PMID- 6929820 TI - A comparison of the polishing properties of human and bovine enamel. PMID- 6929822 TI - Effect of electrical potential on the adherence of Streptococcus sanguis to gold plate. PMID- 6929823 TI - Uptake of fluoride by cells of Streptococcus mutans in dense suspensions. AB - Fluoride uptake by nongrowing cells of Streptococcus mutans GS-5 was assessed by means of the space technique. Uptake was highly concentrative at low fluoride concentrations or low pH. In all, it appeared that fluoride uptake is predictably related to its weak-acid properties and that fluoride can be used, as certain other weak acids are, to estimate intracellular pH. PMID- 6929825 TI - Proceedings of the fifty-seventh annual session, American Association of Dental Schools, 1979-1980. Appendix A. Policy statements and position papers. PMID- 6929824 TI - Proceedings of the fifty-seventh annual session, American Association of Dental Schools, 1979-1980. Presidential address. PMID- 6929821 TI - Developmental communalities in tooth emergence timing. PMID- 6929826 TI - Proceedings of the fifty-seventh annual session, American Association of Dental Schools, 1979-1980. Appendix B. Constitution and bylaws. PMID- 6929827 TI - Programming the third millennium. PMID- 6929828 TI - Women in practice. PMID- 6929830 TI - Uprighting molars. PMID- 6929831 TI - On matters of dissent. PMID- 6929832 TI - On matters of dissent. PMID- 6929829 TI - Local anesthetic. PMID- 6929833 TI - Thirty years of socialistic health care: dentistry in Hungary. AB - The present status of dentistry in Hungary can be understood better through the country's political and economic history. Circumstances led to the development of a primarily socialistic form of health care. However, the mere existence of the private practice of dentistry in the system attests to the incomplete success of socialism in providing for the dental health needs of its citizens. As Americans confront national health issues, an examination of other modes of health care delivery is important to minimize mistakes and optimize benefits. PMID- 6929835 TI - Perceived sources of stress among dental students. AB - A survey of dental students' perceptions of stress indicates that academic factors and faculty relationships with students are the areas that create the most stress. Differences between the four classes in the ranking of several areas reflect the differences in academic and clinical requirements and experience associated with each class. PMID- 6929834 TI - Dental school continuing education courses: ten-year retrospective study. AB - As the public has demonstrated concern for the continuing education of dentists through mandatory requirements, data derived from the continuing education course listings in The Journal and annual reports from ADA Council on Dental Education, Division of Educational Measurements, were used to characterize continuing dental education. Included in the analysis were tuition, course length, and content or subject areas of the courses. PMID- 6929837 TI - Squamous cell carcinoma of the gingiva. AB - The similarity of squamous cell carcinoma of the gingiva to periodontal or periapical disease poses problems in diagnosis and management. A case of squamous cell carcinoma of the gingiva is described. It was initially diagnosed as a periodontal lesion and then as a lesion of pulpal origin. This case demonstrates the importance of being highly suspicious of oral conditions, especially those that do not respond promptly to conventional therapy, and shows the value of microscopic examination of all tissues removed during any oral surgical procedure. PMID- 6929838 TI - Extension of dental abscess to the orbit. AB - A week after dental treatment, a dentoalveolar abscess developed in a 14-year-old boy. Surgical intervention was needed to evacuate pus and remove the cause of infection. It is suggested that initially establishing drainage after dental treatment would have prevented the sequela that ensued. PMID- 6929836 TI - Molar uprighting with T-loop springs. AB - Uprighting of molars is indicated as an adjunct to restorative and periodontal procedures. Limiting conditions exist in which previously reported helical and box-loop springs cannot be used effectively. In those instances, segmental arch wires with T-loops upright the molars efficiently while maintaining control in three planes of space. Furthermore, these loop designs permit immediate engagement of these appliances. Clinical experiences with these springs by students in the professional and graduate dental clinics at the University of Kentucky College of Dentistry lead to the conclusion that: segmental uprighting arch wires with T-loops are easy to fabricate and use; T-looped uprighting springs can be engaged immediately and used efficiently in instances in which helical spring or box-loop uprighting appliances are contraindicated; T-looped uprighting springs offer excellent controlled movements of teeth in three planes of space; acceptance by the patient is favorable; and treatment time, depending on the amount of tooth movement required, is rapid and varies between 8 to 16 weeks. PMID- 6929840 TI - Apexification in a nonvital tooth by control of infection. AB - Incomplete formation of roots in permanent dentition because of death of the pulps is fairly common. Various pastes are used in apexification procedures. It has been suggested that minimum mechanical intervention and removal of infection alone may be sufficient. A case is reported in which this was observed. PMID- 6929839 TI - Oral telescoping orthosis: an aid to functional rehabilitation of quadriplegic patients. AB - The possibility of periodontal disease, chipping of various teeth, or extrusion from use of a mouthstick is minimized with a mouthpiece that covers the complete dentition. Even the simplest of these devices permits increased function for the quadriplegic patient. A case is reported of a young man for whom the oral telescoping orthosis was fitted with a mouthpiece that covered the complete dentition. Damage to the hard or soft tissue structures has not been apparent in eight years of use. Furthermore, the functional capability of the patient has been enhanced. The oral telescoping orthosis is recommended for motivated quadriplegic patients who retain sufficient control of the head and oral and pharyngeal muscles. PMID- 6929841 TI - Provision of preventive dentistry in the hospital environment. PMID- 6929844 TI - Continuing education course listing for July through December 1980. Division of Continuing Education, Council on Dental Education. PMID- 6929843 TI - Acute episodic inflammatory lesions of the mucous membrane and skin. AB - The first consideration in the treatment of erythema multiforme is to search for and eliminate a possible underlying cause. Mild cases require little treatment. Severe forms of the disease must receive prompt, active therapeutic measures. Fluid and electrolyte imbalance must be corrected, secondary bacterial infections must be combated with topical or systemic antibiotics, and large doses of systemic corticosteroids are used for short periods. Without treatment, lesions can persist for many weeks. Mild forms of the disease, which constitute most of the cases, usually subside in a few days to two to three weeks without sequelae. Severe forms persist for three to six weeks longer; sequelae include neurologic changes, corneal opacities, blindness, conjunctival, vaginal, or preputial synechiae, and esophageal strictures. Mortality of all forms has been reported as less than 0.5% but severe cases, at approximately 10%. Recurrences are likely in approximately 25% of the cases; the pattern is variable, chronic, and episodic. PMID- 6929842 TI - Human genetics in dentistry: a summary of three national conferences. AB - By sanctioning these three annual conferences, the Society of Craniofacial Genetics hopes that the impact of human genetics in dental education and dental practice will be realized by the individual student and practitioner. Human genetics and dentistry will continue to have an impact on each other so that dentistry will meet the challenge with innovative educational programs, advances in dental research, and more importantly, interdisciplinary diagnostic and therapeutic concepts. PMID- 6929845 TI - Report on constituent society denture access and educational program. Council on Prosthetic Services and Dental Laboratory Relations. PMID- 6929846 TI - Summary of the 1979--1980 annual report on dental education. Council on Dental Education. PMID- 6929847 TI - 52,000 US physicians receive audiocassette on caries prevention. PMID- 6929848 TI - Researcher uncovers correlation between immunity, periodontitis. PMID- 6929849 TI - Who speaks for the children? PMID- 6929850 TI - Career guidance for dentistry. PMID- 6929851 TI - Some are more equal than others. PMID- 6929852 TI - The peer factor. PMID- 6929853 TI - Malignant primary bone tumours in Jabalpur area. PMID- 6929854 TI - [Changes in electrical capacitance of silicone rubber impression materials during setting process (author's transl)]. AB - Since the silicone rubber impression materials have the high dielectrics, the changes in electrical capacitance during its setting process were measured. The time coordinate of the point of inflexion in the curve of percent changes in its electrical capacitance V.S. time at the setting process were compared with setting time in mechanical measurement. The results were summerized as follows. 1) The degree of advancement of the setting reaction in silicone rubber impression materials were able to be observed by measuring its electrical capacitance. 2) Since the change of the electrical capacitance measured here is corresponding to the setting process of the silicone rubber impression material in this system, the point of inflexion of the curve of the reduced electrical capacitance is the indication of the setting process. 3) The time which demands to reach to this point of inflexion highly corresponds to the setting time of the same material by the mechanical measurements. 4) It is possible to determine the setting time of the silicone rubber impression material by means of measuring the changes in its electrical capacitance. PMID- 6929855 TI - [Studies on the thinning of the upper acrylic resin complete denture with the reinforced palate. (Part 2) Influence of the different palate forms on the thin plate dentures (author's transl)]. AB - In this paper, succeeding the study of the part 1 on the thinning of the upper acrylic resin complete denture with the reinforced palate, it was investigated to keep the same stiffness and strength as the normal resin dentures, and to make the patient comfortable. Besides, many different palate forms exist in the patient's mouth in clinical cases, and so, influence of these forms on the thin plate dentures comes into question. Therefore, 3 types of the palate forms (the standard shape, the extremely large torus and the generally shallow shape) were established, and then the flexural stiffness and strength, and the deformation of the denture bases were scrutinized in this paper. The results obtained in this investigation are as follows: 1) The maxillary torus with sheer bulk had little influence on the flexural stiffness and strength. But, about the generally shallow-shaped denture bases, the mechanical properties dropped a little as compared the normal resin denture bases. The reinforced thin denture bases of which thickness was 60% of the normal one, showed the excellent mechanical properties in spite of the difference of the palate forms. 2) In the upper complete denture base, in spite of the palate forms, anteriority and posteriority of the one were deformed against the load direction around the frontal section through the bilateral canines, and the bilateral ridges of the one were deformed to the load direction around the midline of the denture base. The deformation was extremely decreased by not only the palate but also the whole of the denture base as the reinforced one. PMID- 6929857 TI - [Studies on Pd base ternary alloys for dental amalgam. (Part 2) On the corrosion resistivity (author's transl)]. AB - In the previous paper, the author reported the effect of composition of Pd base ternary alloys on the dimensional change, the compressive strength, hardness and microanalysis by EPMA. In this paper, corrosion resistivity of Pd base ternary alloy amalgam was studied by comparison of reflective light intensity, surface roughness and weight change before and after corosion test in 0.1% Na2S, 0.1% lactive acid and 1% NaCl solution. The main results obtained are as follows: (1) Pd base ternary alloy amalgam showed much higher corrosion resistivity than that of on the market silver-tin-copper amalgam. (2) On the (60 Pd-40 Ag)-Sn alloy amalgam, corrosion resistivity was gradually improved by addition of Sn up to 10 wt% Sn, and the best corrosion resistivity was observed in (60 Pd-40 Ag)-10 Sn among Pd base alloy amalgam tested in this study. (3) On the (60 Pd-40 Ag)-Cu alloy amalgam, corrosion resistivity decreased gradually with increment of Cu content. (4) Weight of (60 Pd-40 Ag)-Sn alloy amalgam was a little increased after corrosion test in 0.1% Na2S solution, but that of (60 Pd-40 Ag)-Cu alloy amalgam showed a tendancy to decrease. (5) Corrosion of Pd base alloy amalgam was observed mainly in the matrix. Tarnish on the core was observed a little. Since fine cut amalgam has the smaller rate of area of core than that of spherical amalgam, surface roughness was comparatively large. PMID- 6929856 TI - [Preparation of carbon fiber reinforced fluid type resin denture (author's transl)]. AB - Transverse strength of cured fluid resins is weaker than that of the heat cured. We have studied to improve the mechanical strength of self-cured acrylic resin by application of carbon fibers as reinforcement and simple methods which must be acceptable for technicians are proposed. A cloth type carbon fiber was the best reinforcement among studied carbon fibers such as chopped or mat. The chopped fibers were difficult to mix homogeneously with fluid resins and effectiveness of the reinforcement was low. Breaking often occurred at the interface between the reinforcement and resin in the cases of mat which gave defects to the test specimens. To prepare reinforced denture, the cloth was trimmed on the master cast after removal of wax and the prepreg was formed with the alginate impression on the cast by Palapress and the cloth. Other steps were same as the usual fluid resin. PMID- 6929858 TI - 3 alpha-, 7 alpha-, and 12 alpha-OH group specific enzymic analysis of biliary bile acids: comparison with gas-liquid chromatograpy. AB - 3 alpha-Hydroxysteroid dehydrogenase (3 alpha-HSDH) from P. testosteroni, 7 alpha HSDH (Escherichia coli ATCC No. 29532) and 12 alpha-HSDH (Clostridium group P, strain C48-50, ATCC No. 29733) were used to directly measure 3 alpha-, 7 alpha-, and 12 alpha-OH groups in extracted human bile-rich duodenal aspirates. Twelve samples chosen from widely differing ratios of cholic/chemodeoxycholic/deoxycholic were computed by solving three simultaneous equations. Comparison of these ratios with those obtained by a) thin-layer chromatography and 3 alpha-, 7 alpha-HSDH assays and b) gas-liquid chromatographic analysis showed no significant difference. Addition of known amounts of pure cholic, chenodeoxycholic, deoxycholic, or lithocholic acid to individual bile extracts gave an appropriate yield of 3 alpha-, 7 alpha-, and 12 alpha-OH groups. The direct (non-chromatographic) enzymic method has the advantages of being rapid, convenient, and inexpensive, and thus suitable for clinical use. PMID- 6929859 TI - Evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for ursodeoxycholic acid, and 7 oxo- and 12 oxo- bile acids. AB - 3 alpha-Hydroxysteroid dehydrogenase (SDH) quantifies ursodeoxycholic acid, 3 alpha,12 alpha-diol-7-one-5 beta-cholanoic acid, 3 alpha-ol-7-one-5 beta cholanoic acid, and 3 alpha,7 alpha-diol-12-one-5 beta-cholanoic acid in a manner similar to the more commonly measured bile acids, exemplified by taurocholic acid. The type of oxygen function at the 7 or 12 position and its orientation at the 7 position has no effect on the rate of reaction of the enzyme. Discrepancies in the glycine/taurine ratios of patient intestinal aspirates containing ursodeoxycholic acid and oxo bile acids, obtained by SDH and gas-liquid chromatographic methods are not a result of the enzyme assay procedure. PMID- 6929860 TI - Orbicularis transposition: concept of a functional correction of uni- or bilateral paralysis of the lower lip. AB - A concept is described for the correction of the lower lip in cases of uni- or bilateral paralysis following injuries of the mandibular branch of the facial nerve, by transpositioning the affected orbicularis muscle to the innervated parts of the upper lip and the zygomatic muscle respectively. The surgical procedure is demonstrated in detail on the basis of several examples. Positive results are clinically and electromyographically evident. Therefore other techniques have been abandoned by us in favour of the transposition of the orbicularis muscle, which is simple in practice and ensures functionally and aesthetically successful results. PMID- 6929861 TI - Cytological tumour diagnosis in maxillo-facial surgery examinations using the fine needle aspiration technique. AB - Based on the question of whether fine needle aspiration cytology may also be successfully applied in the area of maxillo-facial surgery, appropriate investigations were carried out on 121 patients showing definitely localizable tumours in this area. The cytological findings of 107 aspiration biopsies were successfully compared with the results of histological examinations. This comparison showed an agreement between the cytological and histological diagnoses in 75.7 % (n = 81) of the tumours examined. No agreement with histological results due to insufficient aspirates was found in 16.8% (n = 18) of all cases, and for 7.5% (n = 8), cytological results permitted only the suspicion of the presence of a certain tumour. Results of the investigation indicates that fine needle aspiration cytology can in principle also be used effectively in the diagnosis of tumours in the oral, jaw bone and facial region. Further cytological inverstigations are still necessary to confirm the morphological basis for the cytological diagnosis of these tumours. The advantages of the uncomplicated diagnostic method are pointed out. PMID- 6929862 TI - Carcinoma of the oral cavity: on the prognostic significance of the primary tumour site (by organs) in the oral cavity. AB - The prognostic significance of so-called organ sites was investigated in 585 cases with carcinoma of the oral cavity and lips. For the subsamples studied the numerical distribution of TNM categories, life tables and life table comparisons were computed. This produced the following results: 1. There is no demonstrable difference in prognosis between identical T catagories in the organs of the oral cavity. 2. In some cases there is a significant difference between identical N categories in organs of the oral cavity. In the No category this is, however, attributable to the substantial differences in the numerical distribution of T categories. By contrast, a logical explanation for the computationally demonstrable significant differences in the Nx category is not available. The problem is currently being investigated. 3. An assessment of identical TN combinations in the "organs" of the oral cavity proved to be impossible on account of the inadequate number of cases available. The so-called "organ localization" of primary tumours in the oral cavity need not - at least for the time being - be accorded any prognostic relevance. The findings should, however, be re-examined on the basis of greater numbers. PMID- 6929864 TI - The posterior ilium as a donor site for maxillo-facial bone grafting. AB - The anterior iliac crest has been the traditional source of pelvic bone for autogenous bone grafting in the maxillo-facial skeleton. Although the posterior iliac crest is frequently utilized by our orthopaedic colleagues, little attention has been given this site in the oral and maxillo-facial literature. As the posterior crest affords an almost unlimited amount of bone for autogenous grafting in the maxillo-facial region, we feel its use is indicated when very large amounts of bone are required. The techniques for removal of cancellous and cortico-cancellous posterior crest grafts are described in detail. Morbidity of the posterior crest donor site includes possible difficulties with patient positioning, injury to the sacro-iliac joint, injury to the sciatic or cluneal nerves, and severe haemorrhage. Ambulation following the use of the posterior crest has not been a problem. Significant blood loss can be adequately controlled with proper exposure, electrocautery, and bone wax. PMID- 6929865 TI - Midline cervical cleft. A case report. AB - The midline cervical cleft is a rare congenital anomaly. This article describes clinical, operative and histological aspects of this rare lesion. PMID- 6929863 TI - Combined cranio-facial fractures. AB - Clinically, fronto-maxillary injuries may constitute a diagnostic problem, as their severity need not correlate with the patient's general condition. To establish a definitive radiological diagnosis, both normal standard films and tomographs are required. These will help to identify fracture lines involving the base of the skull. Most serious among the complications which may be associated with fronto-maxillary injuries is the occurrence of cerebrospinal rhinorrhoea with potential ascending infection. Other complications include oculomotor dysfunction, obstruction of lacrimal drainage and nasal airways as well as dental malocclusion. Primary surgical management is indicated in compound fractures, suspected intracranial haemorrhage and compression of the optic nerve, while fractures with associated dural injuries and involvement of orbital roofs as well as all other combined maxillo-facial fractures with functional impairment require early secondary management. Open exposure of the fracture site is best obtained through a coronal hair-line incision. Dural injuries are preferentially approached through craniotomies. PMID- 6929866 TI - Bone resection, extra-corporal cryotherapy and immediate re-implantation in the treatment of mandibular tumours. AB - Two aspects have to be considered in the treatment of mandibular tumours: The eradication of the disease, and the maintenance of mandibular continuity to obtain a good functional and aesthetic result. The authors experimented with a cryo-surgical method which consists of mandibular hemiresection, extra corporal immersion of the specimen in liquid nitrogen at - 180 degrees C, followed by re implantation of the mandibular body in its bed. In this way we achieved the eradication of the tumour and produced an auto-transplant for immediate bone grafting. The clinical and radiological progress of four patients with various mandibular tumours, followed-up for three years, is presented. PMID- 6929867 TI - Carotid ligation. A justifiable extension of ablative surgery for malignant tumours in the maxillo-facial region. AB - In 30 cases operated on by ligation of the internal carotid artery, at the Vienna clinic, the average survival time was only 120 days (minimum 2 days, maximum 613 days). However, the immediate surgical risk of the operation is smaller than expected. Long-term postoperative care of the patient appears to be necessary, for psychological reasons. PMID- 6929868 TI - Selective conventional and xero-arteriography of the external carotid artery for control of intra-arterial chemotherapy. AB - The control of intra-arterial chemotherapy by selective conventional and xero angiographic exploration of the external carotid artery is reported. With the aid of a catheter inserted into the superior thyroid, facial or super-facial temporal artery, all the main branches of the external carotid artery can be depicted. Xeroangiography in the area of the external carotid artery is a new method on which no data could be found in the literature. Anatomical variations of the vascular system and vascular lesions caused by surgery, a tumour, or intra arterial chemotherapy are better demonstrated by xeroradiography. The bones and the soft parts are well depicted at the same time in the xeroradiographic pictures; thus the bony masses of the facial and petrous regions, together with the vessels on the bones, in the bones and in the soft parts are visible on one and the same picture. PMID- 6929869 TI - Angiography in the evaluation of cryosurgery efficiency in the treatment of a haemangioma of the face. A case report. AB - The authors present the use of carotid angiography for the diagnosis of maxillofacial cavernous haemangiomata. Radiological investigation of vessels permits the identification of the exact site and range of pathological change but also the evaluation of the mechanism of tissue healing following cryogenic treatment. PMID- 6929870 TI - Experience with transnasal canthopexy. AB - The results are presented of a series of 14 canthopexies in recent trauma cases, 15 for correction of post-traumatic canthal dystopy, 12 for correction of hypertelorism and 8 in Le Fort III midface advancements. The overall results in traumatic cases are acceptable, in hypertelorism a considerable amount of relapse is noted and in Le Fort III osteotomies intercanthal distance enlarges slightly. The reasons for unsatisfactory results are discussed: Pressure ulcers of the skin, lateral pull of the soft tissues, and exaggerated pull on the ligaments seem to be the main factors. In Le Fort III osteotomies the anatomical situation has to be considered. As a conclusion it is suggested that the canthal ligaments should not be detached whenever possible in cases in which the topographical relationship between ligament and medial orbital wall does not have to be changed. PMID- 6929872 TI - A modified technique of guided blind intubation in oral surgery. AB - Intubation in patients for oral surgery will often prove very difficult. The advantages of using a modified, guided, blind nasotracheal intubation in such patients are discussed. PMID- 6929874 TI - Recurrent calcifying odontogenic cyst (case report). AB - A case of calcifying odontogenic cyst is reported in which the lesion recurred after almost 7 years. We would advise a long-term follow-up for patients with this lesion. PMID- 6929871 TI - Temporal double inversion method in reshaping the temporal bulging in a case of Apert's syndrome. AB - A case is reported of Apert's syndrome with severe bilateral balloonings of the temporal region in addition to other typical craniofacial deformities. He had had three previous strip craniectomies. His mentality and intelligence were normal. In order to improve his deformities, the following steps were carried out: 1. 1.5 cm frontal advancement with reshaping the horizontal arc of the supraorbital ridge by out-fracturing. 2. Bilateral temporal double turnover method with internal decompression of the temporal lobe by resection of the sphenoid wing abnormally roofing the temporal lobe. 3. Reduction of the height of the cranial vault. The result was gratifying. PMID- 6929873 TI - Giant-cell tumour-like changes in the maxilla. AB - The authors have analysed 194 cases of giant-cell tumourlike changes of the jaws observed in the hospital over a period of 25 years. On the basis of histological examination and clinical as well as radiological assessment of these cases, diagnostic criteria of this granuloma have been proposed. Neoplastic giant-cell tumours are excessively rare in the jaws. The method of choice in treatment of reparative granulomas is moderately radical operation with removal of the lesion to the margins of healthy tissue or electrosurgical treatment. After non-radical operation reparative granulomas show a tendency to local recurrence. PMID- 6929875 TI - Cement forming tumours of the lower jaw (case report). AB - This publication concerns two cement forming tumours - the centrally cementifying fibroma and the true cementoma. The centrally cementifying fibroma is a rare tumour and has been considered an entity for some time. Our case presents a lesion of a size and a homogeneous histological structure rarely encountered. The operative procedure is also discussed. The progression from the radiolucent to the radio-opaque stage could be observed radiologically in the case of a cementoma. PMID- 6929876 TI - Downward displacement of the eye resulting from orbital emphysema (case report). AB - A case is reported of unusual downward displacement of the eye, occurring in a patient with fractures of the orbital floor and rim. On the basis of the clinical, roentgenological and computerized tomographic scan findings this is interpreted as resulting from a subperiosteal pneumatocoele above the eye ball. PMID- 6929877 TI - Sounds produced by the mandibular joint in young men. A mass examination. AB - More than 2000 young "healthy" men were asked whether they had noticed sounds emanating from the temporo-mandibular joints when being examined in connection with preventive dentistry. They were examined subsequently. About 20% of the patients said they had noticed occasional sounds emanating from the jaw joints; on palpation, crepitation or clicking was found in more than 10%. Auscultatory examination demonstrated sounds in almost 80% of the individuals examined. Phonographically a smaller group demonstrated sounds in more than 90% of the young men. The evaluation of the symptom "sounds in the joint", important in general practice, is not easy when one considers its frequency in "healthy" individuals. PMID- 6929878 TI - The influence of prognathism surgery on the width and the length of the lower third of the face. AB - The width and the length of the face in frontal view as important factors in facial harmony are analysed. Two groups of patients with mandibular prognathism were photographed, analysed and evaluated. The lower third of the face generally becomes shorter after a sagittal splitting operation as well as after a sagittal splitting plus additional medial ostectomy of the lower incisor region. In both groups we did not find a significant change in the width of the face. The impression of broadening the face by the sagittal splitting method is therefore subjective. In both groups, the face became more harmonious indimension following the osteotomies. PMID- 6929879 TI - The excretion of hydroxyproline in urine during the healing of fractures and after sagittal splitting of the mandible. AB - Total excretion of hydroxyproline was measured in patients with fractures of long bones and in patients undergoing sagittal splitting of the mandible. In both patient groups excretion of hydroxyproline was twice that of normal healthy subjects. The amount of excreted hydroxyproline in patients with fractures was related to the site of the fracture, to the age of the patient, and the form of therapy. The excretion of hydroxyproline was found to be variable after wire adaptation of mandiblular osteotomy segments and after sagittal splitting without wire adaptation. Quantitative analysis of the excretion of hydroxyproline in urine does not therefore permit conclusions about the bone healing process. PMID- 6929882 TI - A case of pycnodysostosis. PMID- 6929881 TI - Effect of chlorella on the levels of glycogen, triglyceride and cholesterol in ethionine treated rats. PMID- 6929884 TI - [Susceptibility of clinical isolates of gram-negative enteric bacilli to aminoglycoside antibiotics (author's transl)]. PMID- 6929880 TI - Anemia- and polycythemia-inducing isolates of Friend spleen focus-forming virus. Biological and molecular evidence for two distinct viral genomes. AB - Two distinct clones of Friend spleen focus-forming virus (SFFV), differing in their erythroleukemic potential, are described. These isolates have been cloned free of their associated helper viruses and shown to be replication-defective. Both SFFV isolates have been rescued from rat fibroblast nonproducer cell clones with cloned replication-competent viruses, F-MuLVA and F-MuLVP, obtained from the anemia- or polycythemia-inducing isolates of Friend virus complex, respectively. These rescued viruses induce a rapid proliferative disease associated with the appearance of macroscopic spleen foci and splenomegaly. In addition, each is subject to regulation by the W, Steel (Sl), and Fv-2 host gene loci. These two isolates of SFFV can, however, be distinguished by both biological and molecular criteria. Friend SFFVP induces a rapid polycythemia associated with the appearance of large numbers of erythropoietin (EPO)-independent erythroid colony forming cells in the marrow and spleen. In contrast, SFFVA induces a rapid anemia associated with a progressive decrease in the number of EPO-dependent erythroid colony-forming cells in marrow, and a rapid increase in the number of EPO dependent erythroid colony-forming cells in spleen. Furthermore, the nature of the disease induced by the two isolates of SFFV is independent of the Friend helper virus: SFFVP, rescued from a nonproducer cell clone with either F-MuLVA or F0MuLVP, induced a polycythemic transformation, whereas SFFVA, rescued with either F-MuLVA or F-MuLVP, induced an anemic transformation. The two Friend SFFV isolates can also be discriminated on the basis of translational products encoded by their gag and env genes: SFFVP encodes the amino-terminal gag-gene protein p15, whereas SFFVA encodes the gag-gene proteins p15, p12, and p30. In addition, the SFFV isolates encode nonidentical 55,000-mol wt env gene-related proteins that can be distinguished by analysis of their methionine-containing tryptic peptides. PMID- 6929883 TI - [Pharmacological studies of Chinese herbs. (8) Pharmacological effects of Plantaginis Semen (author's transl)]. PMID- 6929886 TI - Effects of hemodialysis on cardiac performance in patients on regular hemodialysis. PMID- 6929885 TI - [A comparative study of audiograms from two hospital (author's transl)]. PMID- 6929887 TI - Triiodothyronine (T3) suppression test in thyroid disorders: a review of 164 cases. PMID- 6929888 TI - [Measles pneumonia (author's transl)]. PMID- 6929894 TI - The effect of the bite plane splint on the mandibular reposition in bruxers. PMID- 6929891 TI - Reconstruction of digital flexor tendons in "No Man's Land". Part III. Clinical results of secondary tendon grafting for severed flexor tendon. PMID- 6929889 TI - Positive culture of the Janeway lesion in acute bacterial endocarditis. PMID- 6929893 TI - Roentgenocephalometric comparison between class II, division 1 and class II, division 2 malocclusion among Chinese. PMID- 6929892 TI - Thyroid function in Chinese newborn infants. PMID- 6929890 TI - Soluble tumor-associated antigen of human intracranial glioma. PMID- 6929895 TI - Treatment of maxillary cancer with three-combined method. PMID- 6929896 TI - Evaluation of factors influencing the prognosis of gastric cancer after gastric resection. PMID- 6929899 TI - A question of answers. PMID- 6929900 TI - Evaluation of sintered titanium fiber composite as a subperiosteal implant. AB - Seventy-two sintered titanium fiber composite implants were placed subperiosteally and anchored intraosseously on the lateral aspect of 12 dog mandibles. The implants were covered with either Millipore filter, silicone, or left uncovered. Analysis after the animals were killed showed that bone growth into the subperiosteal portion of the implants was maximal at three to six weeks after implantation and remained at a depth of 380 mu through 24 weeks in a majority of the implants. Bone growth into the intraosseous portion also peaked at three to six weeks and remained at 190 to 380 mu through 24 weeks. Covering the implants slowed the rate of osseous ingrowth but did not affect the depth. The implants were well tolerated and the material holds promise for use in oral and maxillofacial surgery. PMID- 6929901 TI - Effect of internal irrigation on frictional heat generated from bone drilling. AB - Frictional heat generated during bone drilling was reduced by internal irrigation compared with external or no irrigation. This was based on an in vitro study using two bur designs at low rotational speeds to prepare experimental cavities to varying depths. PMID- 6929897 TI - Two-year experience with patch testing. PMID- 6929902 TI - A new technique for closure of the oroantral fistula. AB - A surgical procedure has been devised to use the connective tissue under the palatal mucosa for the closure of oroantral fistulas. This procedure has been successfully performed on 13 patients, and it has proved to have a broader application and greater certainty of results than conventional techniques. PMID- 6929898 TI - Sulfation of dopamine and other biogenic amines by human brain phenol sulfotransferase. PMID- 6929903 TI - Cardiopulmonary resuscitation: a teaching aid. AB - Laboratory dogs are used to demonstrate and practice cardiopulmonary resuscitation (CPR) procedures. Cardiovascular collapse, cardiac arrest, and ventricular fibrillation are produced in anesthesized dogs and then managed by the student. The laboratory exercise focuses and emphasizes CPR material taught in the classroom and on mannequins. With the current emphasis on CPR training and certification, we recommend the concept to the dental profession as an added dimension in teaching CPR. PMID- 6929904 TI - Anesthetic considerations for the oral surgery patient with hemophilia. AB - Hemophiliac patients undergoing oral surgical procedures can be a challenge for both dental and medical personnel involved in their care and treatment. Anesthetic management of hemophiliac patients may be safely attained by various pain control techniques including local anesthesia. Possible complications resulting from administration of anesthesia must be kept in mind at all times. Preparation, caution, and gentleness are necessities for administration of safe and effective anesthesia to the hemophiliac patient. PMID- 6929907 TI - Choriocarcinoma metastatic to maxillary gingiva. AB - A rare metastatic lesion is presented in a 77-year-old black man. The primary disease was fulminating from the time of admission, and diagnosis was established by oral biopsies. The unusual features in this case, in addition to the rarity of the tumor, are the age and race of the patient, the peculiar metastases, and difficulty in identifying a primary site. PMID- 6929909 TI - An appliance for jaw dilation in prolonged posttraumatic and postsurgical trismus and fibrosis. AB - A simple appliance is described that is capable of exerting a controlled positive force against a patient's maxilla and mandible, gently stretching the muscles of mastication, opening the mouth, and obtaining motion of the pemporomandibular joint. Its effectiveness has been proved during a period of 11 years. PMID- 6929908 TI - Necrotizing sialometaplasia of the cheek: report of case and review of literature. PMID- 6929910 TI - Sleep apnea syndrome: correction with surgical advancement of the mandible. AB - Mandibular retrognathism is occasionally associated with sleep apnea syndrome. Most cases of this disorder have, until now, been treated with permanent tracheotomies. One patient with this syndrome was treated with surgical advancement of the mandible with bilateral C osteotomies and iliac corticocancellous grafts. Complete reversal of the sleep apnea symptoms and return of the sleep EEG to normal resulted after surgery. Although further study needs to be done, mandibular advancement would appear to be a preferable alterantive to tracheotomy for such patients. PMID- 6929911 TI - Practice styles and opportunities in periodontics. AB - A survey of the 3,048 Active and Affiliate members of the American Academy of Periodontology was conducted by the Task Force on Manpower of the Academy to elicit information concerning practice styles and perceived opportunities for practice. Responses from 1,580 periodontists are presented in tables which include data on general demographics of periodontists, expected age at which partial and full retirement will take place, forms of practice, weeks per year and hours per week spent in practice, number of patient visits per year, number of practice locations, years in present community, population of present community, average distance traveled by patients in the periodontal practice, numbers of dentists referring to the practice, weeks waiting time to examine new patients and to begin new treatment series, patient load, preferences regarding weeks of advance booking, perceptions regarding the supply of periodontal services in the respondent's local area as well as in other areas known to the respondent, and factors which influence selection of a practice location. Data presented were collected between November of 1978 and April, 1979. PMID- 6929913 TI - Results of periodontal therapy related to tooth type. AB - Certain teeth or groups of teeth are prone to develop more severe periodontal destruction than other teeth in the same individuals. A test was made to assess if these same teeth or groups of teeth also respond less favorably to periodontal therapy than other teeth. Data from a longitudinal study of periodontal therapy for 78 patients over 8 years were analyzed with regard to effect of tooth types on treatment results. The response to periodontal treatment was only marginally related to tooth type with the most favorable responses in the maxillary and mandibular anterior teeth and the least favorable responses in the maxillary molars and bicuspids. Although a number of these differences were significant statistically, the actual values were too small to be of appreciable clinical significance. The overall prognosis for treatment of periodontal pockets apparently is good for all tooth types and this observation applies to moderate as well as to deep pockets. PMID- 6929912 TI - Some microbiological and histopathological features of periodontal disease in man. PMID- 6929914 TI - Clinical assessment of free gingival graft effectiveness on the maintenance of periodontal health. PMID- 6929905 TI - Clinico-pathological conference. Case 31, part 2. Ameloblastoma of the maxillary sinus. PMID- 6929906 TI - Pathologic fracture of the mandible resulting from osteomyelitis: report of cases. AB - Two cases of pathologic fracture of the mandible resulting from chronic osteomyelitis are described. The first case was treated successfully by antibiotic therapy followed by resection of the affected bone and iliac bone grafting after six months of follow-up care. In the second case, a patient with a history of diabetes mellitus, a fracture of the condyloid process occurred because of extension of the Actinomyces infection after extraction of the third molar. Because antibiotics failed to prevent exacerbation of the disease, the patient was given human gamma globulin. Then, all the signs of inflammation disappeared gradually with no evidence of recurrence for more than a year. There was no spontaneous bony healing of the fractured site. PMID- 6929915 TI - Relationship of occlusion and periodontal disease. Part XI. Relation of axial inclination (mesial-distal) and tooth drift to periodontal status. PMID- 6929917 TI - Some personality determinants of denture preference. AB - Sixty-two edentulous patients were treated with complete dentures. A correlation was evident between Oriental ethnocultural background (connected with socioeconomical shortcomings) and a preference for white, shining denture teeth rather than natural-looking ones. A similar trend was observed in individuals with a low score of personal satisfaction who chose brilliant, beautiful teeth. In this study, the patient's choice was motivated by compensatory strivings which were more pronounced in those with a low self-esteem rating. This is a consideration that should influence the prosthodontist's approach. PMID- 6929916 TI - A periodontal probe that measures to one tenth millimeter. AB - A periodontal probe has been developed which utilizes a vernier gauge to permit direct measurement to one-tenth millimeter. This configuration eliminates the need for multiple step measurements using stents or calipers. The probe can be sterilized easily to make measurements during surgical procedures. The probe should prove useful in clinical research, minor tooth movement and patient treatment documentation. PMID- 6929918 TI - Attitudes of dentists in British Columbia toward removable prosthodontics. PMID- 6929919 TI - Experimental investigations on the cytotoxic nature of methyl methacrylate. PMID- 6929920 TI - Variability of passively recorded centric relation. AB - 1. Centric relation in patients without clinical signs or symptoms of mandibular dysfunction is a small range of mandibular positions. 2. The average range of shift was 0.302 mm mediolaterally and 0.278 mm anteroposteriorly for all five subjects. 3. There is no significant difference between the ranges of mandibular positions recorded using chin-point guidance, chin-point guidance with ramus support, or bimanual manipulation. 4. This technique of comparing mandibular positions dictated by centric relation records is sufficiently sensitive to reveal minimum ranges of biologic variation. PMID- 6929921 TI - Provisional restorations for traumatically injured teeth requiring endodontic treatment. AB - The acid-etch-composite resin technique is used to retain a provisional restoration during the course of endodontic treatment. As described, the use of a gutta percha cone during the buildup and bonding to adjacent teeth provides the following: (1) good esthetics during endodontic treatment, (2) good support for rubber dam placement, (3) good entry to the canal, (4) good coronal seal for medication within the canal, and (5) good function as required by the provisional crown. PMID- 6929922 TI - An investigation of epoxy resin dies. AB - 1. Complete crown epoxy resin dies are undersized. 2. MOD onlay epoxy resin dies are accurate. 3. Detail duplication of epoxy resin dies is comparable to that of die stone. 4. Hardness values of epoxy resin are generally less than those of die stone. The hardness of Epoxydent closely approached that of die stone. PMID- 6929925 TI - A method for obtaining the reverse image of an ear. AB - A method was described in which the morphology of a patient's remaining ear and its spatial relationship were duplicated on the contralateral side. The technique used parallel lines transferred to casts, a vertical camera capable of making reproductions of three-dimensional objects, and tracing paper. PMID- 6929924 TI - Muscle physiology during functional activities and parafunctional habits. AB - Many of the signs and symptoms of muscle pathosis and fatigue are better treated when the underlying cellular and biochemical mechanisms of muscle function are approached. The basic structural and functional components of muscle tissue and the biochemical cellular activity of muscle contraction have been described. The muscle physiology of the functional activities of chewing and swallowing have been compared to the muscle physiology of the parafunctional habits of clenching and bruxing. PMID- 6929926 TI - Total rhinoplasty or prosthesis? AB - This article outlines the basic anatomy of the nose as it relates to a pleasing facial appearance and discusses the problems involved in the reconstruction and rehabilitation of the patient sustaining total rhinectomy. PMID- 6929923 TI - Effectiveness of hardening films on die stone. AB - 1. Cyanoacrylate resins and resinous die hardeners effectively improved the hardness and abrasion resistance of stone dies. 2. Application of liquid resins followed by blotting and/or blowing with compressed air produced an improved surface without clinically significant dimensional change. The extent of film buildup was qualitatively related to the viscosity of the resin. 3. Application of multiple coats of resin or simply soaking the dies in resin without further blotting or other mode of removal of the excess produced a thick film which can obliterate surface detail. PMID- 6929927 TI - Relation of Gothic arch apex to dentist-assisted centric relation. AB - These data suggest that the widely held belief that thumb pressure can position the mandible consistently more posterior than the position indicated by the Gothic arch apex is unfounded. Furthermore, this study provides no evidence to support the contention that the dentist-assisted jaw relation is more reproducible than the relation indicated by the Gothic arch apex. PMID- 6929928 TI - Dust in dental laboratories. Part II: Measurement of particle size distributions. AB - It has been demonstrated in a previous study that threshold limit values of various elements or compounds could be considerably exceeded in various work operations in the dental laboratories when appropriate ventilation systems were not used. This refers to working with chromium-cobalt alloys, amalgam dies, porcelain, and gypsum. In the present study, size distributions of particles arising from cutting, grinding, or polishing of alloys, gypsum, porcelain, or denture base material in dental laboratories have been measured. The particle size distributions were evaluated by means of light and electron microscopy as well as by coulter-counting techniques. The measurements revealed the occurrence of a high proportion of respirable dust associated with these operations. consequently, the use of efficient ventilation systems is strictly necessary to ensure industrial safety with respect to air pollution in the working environment of dental laboratories. PMID- 6929929 TI - The kinesiographic measurement of jaw displacement. PMID- 6929934 TI - [Treatment of chronic nonspecific lung diseases with aerosols and artificial oxygen ventilation of the lungs]. PMID- 6929932 TI - Baccalaureate dental hygiene graduates' perceptions of community dental health employment. AB - A survey was conducted on 352 University of Iowa baccalaureate dental hygiene graduates to determine the percentage of graduates that had been employed in community dental health, the percentage that were interested in community dental health, employment, and the respondents' perceptions of community dental health employment as it related to the dental hygienist. Specific findings of the study included: 1. Less than 15 percent of the respondents had been employed in community dental health. 2. Nearly 40 percent of the respondents were interested in community dental health employment. 3. Subjects were more opinionated and had more positive impressions of the intrinsic factors than of the extrinsic factors that affect the dental hygienist's employment in community dental health. 4. Subjects who were interested in and/or who had been employed in community dental health had significantly greater positive impressions of community dental health employment than those not interested. PMID- 6929930 TI - Clinical quality and delegation in a private dental office utilizing expanded function dental auxiliaries. PMID- 6929936 TI - Perforation of Meckel's diverticulum in the newborn. PMID- 6929931 TI - The use of medical diagnostic procedures in primary dental care. PMID- 6929933 TI - [Experience of radiotherapy for extramedullary leukemia with the mass formation (author's transl)]. PMID- 6929935 TI - Neutrophil surface markers in chronic myelocytic leukemia. PMID- 6929937 TI - Microsurgery in urology. PMID- 6929938 TI - A ten year case history of air fluidized support. PMID- 6929940 TI - The Grievance Committee: an asset for organized medicine--experiences of the Charleston County Medical Society. PMID- 6929939 TI - Myotonic dystrophy: case report and review of the literature. PMID- 6929941 TI - 20 alpha-Hydroxysteroid dehydrogenase activity and the X-zone of the female mouse adrenal. PMID- 6929944 TI - Foreign DNA sequences in crown gall teratomas and their fate during the loss of the tumorous traits. PMID- 6929943 TI - A serum protein polymorphism determinant on chromosome 9 of Mus musculus. AB - Genetic polymorphism for a previously undescribed serum protein has been found among inbred strains of Mus musculus. The new serum protein locus, gene symbol Sep-1, has been located on Chromosome 9, gene order Lap-1--Sep-1--Mpi-1--d--Mod 1, by utilizing information obtained from 52 recombinant inbred strains together with standard genetic backcrosses. The strain distribution pattern for this locus, supernatant malic enzyme, and transferrin also on Chromosome 9, are given for 67 inbred strains. Because the genotype of SEP-1 can be determined for individual mice without killing them, Sep-1 is a very useful gene in linkage studies and experimental biology. PMID- 6929942 TI - Androgen metabolism by mature rabbit epididymal tissue: the effects of castration and androgen replacement. PMID- 6929945 TI - Recombination in bacteriophage P2: recA dependent enhancement by ultraviolet irradiation and by transfection with mixed DNA dimers. AB - Bacteriophage P2 is known for its exceptionally low rate of spontaneous (non integrative) recombination, which however may be stimulated by ultraviolet irradiation of the phage. We show here that ligated dimers, made in vitro from mixtures of DNAs of two P2 mutants, upon transfection of lysozyme-spheroplasts give origin to recombinants at high frequency. While spontaneous P2 recombination occurs independently of the main recombination pathway of the bacteria, P2 recombinant formation following either ultraviolet irradiation or transfection with DNA dimers requires at least some element of such a pathway, since it is absent or greatly reduced in recA- bacteria or spheroplasts. It would seen that, in the course of its lytic development, P2 deploys a mechanism that inhibits the main recombination pathway of the host cell, or assumes DNA configurations refractory to it. PMID- 6929946 TI - Assignment of functions to segments of the DsRNA genome of the Ustilago virus. AB - The genome of the 3 Ustilago maydis viruses, known to be associated with the "killer phenomenon", is segmented. The distribution of the viral functions on different segments has been partly resolved. The reported comparative study, of a series of mutants with deleted segments of the genome and of hybrid variants containing segments of the related viruses, provides additional information on the location of various functions and on the interrelations among the different segments. The data indicates that the functions related to the maintenance of the viral information are located on the H segments. Among these segments some function overlap exists. The maintenance of the M and L segments is dependent on the functions located on the H segments. The functions related to the killer phenotype are distributed on the M2 and L1 segments. These functions include the determination of the killer specificity. The H segments play no role in the determination of the killer specificity and the specificity is determined by the M2 segment. The L segment is essential for the expression of the killer phenotype but it is suggested that the information for the toxin resides in the M2 segment. PMID- 6929947 TI - Excision and repair of mismatched base pairs in transformation of Streptococcus pneumoniae. AB - The use of heteroduplex DNA molecules as donors in pneumococcal transformation makes it possible to follow the fate of each DNA strand. The integration efficiency of each strand depends strongly upon the single base changes it carries. The function (hex) which reduces drastically the transformation yield of markers referred to as low efficiency (LE) tends to remove either donor strand without respect ot which one is introduced. In the case of high efficiency (HE) markers the reduction in the transformation yield involves the elimination of only one donor strand. For a given locus it can be either one depending upon the mutation. The reduction in transformation yield can be less drastic for HE markers than for both strands of the LE markers. These data are discussed in terms of differences in the affinity for mismatched base pairs. We have studied the transfer of information from each donor DNA strand to the recipient genome, on the basis of differences in the rates of phenotypic expression of a given marker introduced on opposite strands. Results show that, as in the case of LE markers, the information from HE markers, when introduced on the strand recognized by the hex function, is transmitted to both strands of the recipient molecule. Correction of the recipient strand to homozygosis probably accounts for this information transfer. These results, together with earlier investigations, strongly suggest that the hex function is an excision-repair system acting on donor-recipient base pair mismatches. PMID- 6929949 TI - [Testicular infiltration in acute lymphoblastic leukemia in childhood]. PMID- 6929948 TI - Length determination of the terminal redundant regions in the DNA of phage T7. AB - The length of the terminal redundant regions in T7 DNA has been determined by two methods. One involved the specific labeling and isolation of the redundant DNA fragment and determination of the molecular weight by polyacrylamide gel electrophoresis. A value of 150 +/- 10 nucleotide pairs was obtained. The other determination based on a correlation of the melting temperature of the redundant region to that of whole T7 DNA confirmed the result obtained by the first method. PMID- 6929950 TI - Hypercalcemia in chronic myelogenous leukemia. PMID- 6929951 TI - More on lithium and leukemia. PMID- 6929952 TI - Annual address of the president. Challenge of medicine in the eighties. PMID- 6929953 TI - Evaluating the elderly patient. PMID- 6929957 TI - Combined endodontic-periodontic lesions with obscure aetiology. PMID- 6929955 TI - [How normal is the normal cell content of cerebrospinal fluid?]. PMID- 6929954 TI - The periodic health examination--the Canadian approach. PMID- 6929956 TI - [Well marked mass of leukemic cells around an optic nerve infiltrated by leukemic cells in a child (author's transl)]. PMID- 6929959 TI - New Zealand Committee on Adverse Drug Reactions: fourteenth annual report 1979. PMID- 6929958 TI - Intracranial abscess secondary to dental infection. PMID- 6929960 TI - The contraceptive practice of abortion patients. AB - An analysis is made of the contraceptive practice of 100 women prior to abortion. Half the women were not using any method during the month they became pregnant. Problems with the pill, risk-taking behaviour and fears of infertility, were the commonest reasons for non-use. In the 50 percent who were using a method, failure was most commonly due to human error and to the use of less reliable methods. Psychological and social factors were seen to be important determinants of behaviour. This study emphasises the need for remedial action. PMID- 6929961 TI - Viral hepatitis. PMID- 6929962 TI - Specialists in general practice. PMID- 6929963 TI - Investment in medical research. PMID- 6929964 TI - Coronary artery surgery. PMID- 6929965 TI - Manipulative medicine. PMID- 6929966 TI - Idiopathic oedema and diuretic dependence. PMID- 6929967 TI - Medic-alert certifications. PMID- 6929970 TI - Electromyographic feedback treatment of hemiplegia. AB - Electromyographic treatment of four elderly hemiplegics was undertaken. Results showed an improvement on what had been obtained by standard physiotherapy. The degree of communication possible seems to be a critical factor in the result. PMID- 6929969 TI - Ruptured abdominal aortic aneurysm: a five year review. AB - This review of patients presenting with ruptured abdominal aortic aneurysm over a five year period shows a high mortality. The natural history of the problem of abdominal aortic aneurysm and the place of elective aneurysmectomy is stressed. Factors affecting the outcome after rupture in the forty-six patients presenting in this five year period are reviewed. Ten patients survived to leave hospital. PMID- 6929968 TI - Subclinical hypothyroidism. AB - Clinical and biochemical indices of thyroid function were compared in 18 euthyroid control subjects and 54 patients at risk of developing hypothyroidism, and the assessment repeated after a four-week trial of oral triiodothyronine (T3) 40 microgram daily. Patients with minor elevation of the pre-treatment serum TSH concentration (5-15 microU/ml) showed significant reduction in the free thyroxine index (FTI), prolongation of the basal ankle reflex half-relasation time (ART), and shortening of the ART after oral T3 treatment, when compared either to control subjects or to patients with a normal TSH level. It is concluded that patients with minimal TSH elevation have minor but parallel abnormalities of both thyroid hormone concentration and action. PMID- 6929971 TI - Deaths from influenza A, subtype H1N1, during the 1979 Auckland epidemic. AB - We report seven cases of influenza-associated deaths in persons under twenty-two years of age, five of whom were previously fit and well, during an influenza A epidemic affecting Auckland city during the second quarter of 1979. Despite intensive care in three of the patients, all followed a similar course of fatal hypoxaemia. The failure of appropriate therapy in those patients with staphylococcal superinfection was a further feature. Influenza A-subtype H1N1 was isolated from throat swabs and/or post-mortem lung in five of the cases. This subtype has not been responsible for epidemic influenza or influenzal outbreaks in New Zealand since the early 1950s. The isolates were most similar to the A/Brazil/11/78 strain which has not previously been isolated in New Zealand. The susceptibility of young people is attributed to lack of previous antigenic exposure in those born since the mid-1950s. PMID- 6929972 TI - Coexisting Paget's disease of bone and hyperparathyroidism. AB - A patient with Paget's disease of bone and primary hyperparathyroidism is described. It has been suggested that a metabolite from pagetic tissue might stimulate parathyroid cell function. To test this, serum parathyroid hormone (iPTH) levels were measured by radio immunometric assay in 106 patients with Paget's disease of bone and 139 control subjects. There was no significant difference between the mean levels of the two groups. Of five sera with elevated PTH levels QUOSO extraction revealed an interfering substance in 3/5 from control patients tested and extractable iPTH in 2/2 from Paget's patients. One of the latter had renal failure. The results suggest that increased parathyroid function is unlikely to be a primary event in the genesis of Paget's disease of bone. PMID- 6929973 TI - Control of thrombocytosis by plateletpheresis using a cell separator. AB - Three patients with marked thrombocythaemia secondary to myeloproliferative disorders were treated with plateletpheresis using an Aminco cell separator and myelosuppressive agents. Immediate control of the raised platelet count was achieved by plateletpheresis and long-term control by the concomitant cytotoxic therapy. The indications for plateletpheresis in patients with marked thrombocytosis are discussed. PMID- 6929974 TI - Two versus four legs in energy terms. PMID- 6929975 TI - Female sterilisation: a five-year follow-up in Auckland. AB - During the year 1972/73 sterilisation by tubal occlusion was performed at National Women's Hospital on 831 women with a mean age of 32.5 years and a mean parity of 4.6. Two were unknowingly pregnant at the time of operation and eight became pregnant within five years mainly because or recanalization of the tube. Eighty-one percent had no regrets about being sterilised but eleven women experienced a major degree of regret. Eight patients had sought reversal of their sterilisation. Following the operation libido was decreased in 10% of Europeans and 45% of Maoris. Menorrhagia was a common complaint after sterilisation and 7.5% had a hysterectomy within five years. PMID- 6929977 TI - An evaluation of geriatric service in a public hospital. AB - A retrospective survey of the one and half years between 1975-77 was conducted to evaluate the medical problems of the elderly in a community served by a large urban public hospital. Medical records of 238 patients were scrutinised to assess the incidence of most common diseases, their outcome and the success of rehabilitation programme. There were more females (58.4%) than males (41.6%) and the mean age of patients was 78 years. The cerebrovascular problems were the commonest followed by cardiovascular and musculoskeletal disorders. Majority of the patients, however, had multiple problems. Twenty-eight percent of the patients died in the hospital and of the remaining, 83% were successfully rehabilitated. A large number of the patients discharged home needed provision of domiciliary services in the early stages and the readmission rate was 3%. PMID- 6929978 TI - Antenatal screening for gonorrhoea. PMID- 6929976 TI - Hospital admissions during the first five years of life: a report from the Dunedin Multidisciplinary Child Development Study. AB - Admissions to hospital experienced by 991 Dunedin children in the first five years of life are described. Changes in behaviour reported by the mothers as following these admissions were related to the age of the child, circumstances of admission, and extent of contact with parents. Twenty-seven percent of the children had been in hospital and 7% more than once. The majority of admissions were short, particularly for the older children, and parent contact was usual. The majority of admissions were not followed by reported changes in behaviour. Children between 13 and 36 months had the highest incidence of reported behaviour deterioration (25%). Children between 36 and 60 months had the highest incidence of improved behaviour (22%). These results are discussed in relationship to other research on the effects of admission to hospital on young children. PMID- 6929979 TI - Rubella and oral contraceptives. PMID- 6929980 TI - The preoperative chest x-ray. PMID- 6929981 TI - A prospective study of hip fracture patients. AB - This prospective study of 85 femoral neck fracture patients has shown that these patients are older than other 65 + orthopaedic admissions and match the age of geriatric admissions. A disproportionately high number of the patients fall into the disabled, less mobile, not married and institutionalised categories. Disuse is suggested as one aetiological factor in the generation of osteoporosis. Rehabilitation is compromised by the significant delays in discharge which occur when patients are not able to return to their original environment, particularly where placement is required in a geriatric unit or in a private hospital. PMID- 6929983 TI - Bile peritonitis secondary to perforation of the gallbladder. A review of the Dunedin experience 1955--1979. AB - A retrospective study analysing patients admitted to the two Dunedin hospitals between 1955 and 1979 revealed five cases of bile peritonitis secondary to perforation of the gallbladder. All patients were treated surgically and recovered. The literature is briefly reviewed. PMID- 6929984 TI - A ring 15 chromosome in a girl with minor abnormalities. AB - A 13 year old girl with a ring 15 chromosome is described. The only major clinical abnormalities were shortness of stature and mental dullness. The usefulness of a chromosomal investigation in patients who have relatively minor mental and/or physical defects is emphasised. PMID- 6929982 TI - Immunisation in the first year of life. AB - Over 10 percent of a group of 1180 Christchurch infants received either no immunisation, incomplete immunisation or late immunisation during the first year of life. Failure to provide the child with the recommended course of immunisation was most common amongst families of non-European ethnic origin, single parent families and families with depressed living standards. PMID- 6929985 TI - Urinary creatinine excretion during pregnancy. AB - Twenty-four urinary creatinine excretion was measured in pregnant women. Three groups were selected, the first were those who were normotensive throughout pregnancy and had normal fetal outcome, the second were those who developed hypertension during pregnancy with normal fetal outcome and the third group were those who had twins with normal fetal outcome. The normotensive and twin pregnancies had creatinine excretion rates which were not statistically different. The creatinine excretion rate in the hypertensive pregnancies was statistically significant when compared with the normotensive population. PMID- 6929987 TI - Particulate contamination in New Zealand intravenous solutions. AB - The New Zealand Department of Health sampled intravenous solutions readily available, February to April 1978, for testing at DSIR. Four out of a sample of 12 production batches taken from five manufacturers failed to comply with the requirements for particulate matter of the British Pharmacopoeia 1973 and of the New Zealand Transfusion Advisory Committee. A further 15 batches were rejected when retesting products of two manufacturing units where problems with particulate contamination had been descovered. Subsequently, action has been taken to deal with these problems. PMID- 6929986 TI - Small bowel tumour presenting as Sister Joseph's nodule. AB - A case of a secondary carcinoma of the umbilicus is presented, for which no cause could be found. At laparotomy a stenosing adenocarcinoma of the ileum was resected. This is believed to be one of the first recorded cases of Sister Joseph's nodule being associated with carcinoma of the small bowell. PMID- 6929988 TI - Methanol poisoning. PMID- 6929989 TI - The psychiatric aspects of violence. PMID- 6929991 TI - Royal New Zealand College of General Practitioners. PMID- 6929990 TI - We are not the doctors, we are the disease: a view of health planning. PMID- 6929992 TI - BQ 22-708, a new antihypertensive agent with vasodilator properties. PMID- 6929993 TI - Viral hepatitis and dentistry. PMID- 6929994 TI - Treatment of malaria. PMID- 6929995 TI - The prevalence of systemic lupus erythematosus (SLE) in Dunedin. AB - The prevalence of SLE was determined in Dunedin, where there is a relatively stable population with ready access to hospital facilities. The overall prevalence of the disease was 1/6780 and its prevalence in women 1/4312. PMID- 6929997 TI - Bioavailability of two preparations of frusemide. AB - This study examined the relative diuretic effectiveness of batches of 40 mg tablets of the Frusid and Lasix formulations of frusemide in health volunteers. There were no significant differences in the urinary volume or urinary contents of Na+, K+ and Cl- following the oral administration of either preparation. It is concluded therefore that the batches studied had equivalent bioavailability. PMID- 6929998 TI - Electrocardiographic findings in a partly urbanised Polynesian population. The Funafuti survey. AB - Electrocardiographic changes defined as probable or suspect ischaemic heart disease and coded according to the Minnesota coding system, were found in 14 (10.3 percent) of 136 Funafutians surveyed. Of these abnormal electrocardiograms, nine were classified as "probable" ischaemia and five as "suspect" ischaemia. There was a higher prevalence of electrocardiographic ischaemia in the female population compared with the male population of Funafuti. This is consistent with the greater degree of obesity and higher prevalence of diabetes previously reported in females in this population. PMID- 6929996 TI - Recurrent disc prolapse as a cause of recurrent pain after laminectomy for lumbar disc lesions. AB - Recurrent disc lesions occur in about 19 percent of patients having a primary laminectomy and occurring in just under half (46 percent) of those suffering recurrent pain. The clinical features are similar to those of a primary disc lesion. The most likely site (two out of three) is the same disc level as before, with an equal probability of involving the previous or its opposite side. Re operation appears to carry a good prognosis, with 80 percent good results, while with conservative treatment 45 percent will settle down in less than three months. PMID- 6930000 TI - The present status of electroconvulsive therapy. PMID- 6929999 TI - Dysphagia of pseudobulbar palsy successfully treated by hypnosis. PMID- 6930003 TI - Chronic bronchitis and emphysema. PMID- 6930001 TI - Liver function in a group of hospitalised alcoholics and non-hospitalised problem drinking probationers. AB - Twenty non-hospitalised problem male drinkers and 20 hospitalised problem drinkers were investigated by the Michigan alcohol screening test (MAST) and by liver function tests (AST, ALT). The MAST scores of the non-hospitalised group were above normal and indicative of alcohol addiction, AST and ALT tended to be higher in the hospitalised but not indicative of severe liver damage. PMID- 6930002 TI - Self poisoning: who supplies the drugs? 100 examples. AB - One hundred self-poisoners, consecutively referred to the psychiatric liaison service at Auckland Hospital were questioned regarding the source of the substances taken, the taking of regular medication and their last contact with a doctor. In total, 82 percent took legitimately prescribed medications, in 67 cases prescribed for themselves, while 12 percent bought over-the-counter preparations. Alcohol was associated in one-third of all cases. In one half of all cases the substance ingested had been prescribed at the last visit to a doctor. These patients were statistically more likely to be depressed, to be taking regular medication and to have taken a previous overdose. Two-thirds of all cases had seen a doctor no more than a month prior to self-poisoning. PMID- 6930004 TI - New Zealand committee on adverse drug reactions: fourteenth annual report 1979. PMID- 6930005 TI - Cigarette smoking by New Zealand doctors: results from the 1976 population census. AB - In the 1976 New Zealand population Census, 3584 male and 505 female doctors aged 25 years and over responded to a question on cigarette smoking. Twenty percent of men and 17% of women doctors smoke cigarettes regularly compared with 40% of men and 30% of women in the general population over 25 years. Cigarette smoking by male doctors has fallen from 37% in 1963 to 20% in 1976. There has been a minor increase by women doctors since 1972. Obstetricians smoke more heavily (27%) than other specialty groups but have reduced their smoking since 1972. Male physicians have the lowest rate of smoking (16%). About one in four of those in other professions are cigarette smokers compared with about half those in other occupational groups such as labourers, transport and service workers. PMID- 6930006 TI - Plasma and urine concentrations of acebutolol and its acetyl metabolite in patients with renal functional impairment. AB - This study was undertaken to examine the elimination of orally administered acebutolol and its major acetyl metabolite in four healthy controls and seven patients with varying degrees of renal functional impairment. Analysis of acebutolol and its metabolites was undertaken using a high performance liquid chromatographic method. Plasma concentrations of acebutolol and the acetyl metabolite were greater in patients with renal functional impairment than in controls. The elimination of acebutolol did not appear to be influenced by impaired renal function. However the elimination of the acetyl metabolite decreased as renal function diminished. Acebutolol has a major non-renal route of elimination, but the acetyl metabolite (also a beta-adrenoreceptor blocking drug) is primarily excreted by the kidney and may accumulate in renal failure. PMID- 6930007 TI - Ocular cryptococcosis in New Zealand. AB - A patient with unexplained lung abscess six years previously, developed chronic meningitis, and later, bilateral chorioretinitis. The organism found was Cryptococcus neoformans. The patient was successfully treated with amphotericin B and 5-fluorocytosine. PMID- 6930009 TI - The consultants' letter. PMID- 6930008 TI - Pseudomembranous colitis in a patient on rifampicin and ethambutol. AB - A fifty-seven year old male with renal tuberculosis developed pseudomembranous colitis on rifampicin and ethambutol. Diarrhoea occurred within a week, and six weeks after commencing these antituberculous agents he developed typical sigmoidoscopic and biopsy findings. Withdrawal of the drugs led to rapid recovery. Repeated challenge testing indicated that the symptoms were worse when rifampicin was given, but a test dose of ethambutol also produced temporary aggravation of the diarrhoea. PMID- 6930010 TI - Human sexuality: a survey of the sexual experience of medical students, University of Otago. PMID- 6930012 TI - Non-migrainous headache. PMID- 6930013 TI - Interim report of the stress effects on the recovery teams after the Mt Erebus disaster, November 1979. PMID- 6930011 TI - A hospital/community based rehabilitation programme for chronic psychiatric patients: a retrospective view. PMID- 6930014 TI - Report to the Minister of Health of an investigation into allegations of an association between human congenital defects and 2,4,5-T spraying in and around Te Kuiti. PMID- 6930015 TI - Outpatients. PMID- 6930016 TI - 2,4,5-T and cancer. PMID- 6930017 TI - Anthropometric studies on Dunedin five and six year old children. PMID- 6930018 TI - Donor and therapeutic leucapheresis: three years experience with the aminco continuous-flow celltrifuge. PMID- 6930019 TI - Temporal arteritis causing admission to hospital in Auckland. AB - A restrospective eight year review of patients hospitalised with temporal arteritis in Auckland shows that the features of the disease were headache, tender swollen temporal arteries, weight loss and fever very common, and blindness occurred in a quarter of the patients with definite temporal arteritis. The importance of making the diagnosis is discussed. PMID- 6930020 TI - Legionnaires' disease in Wellington. AB - Legionella pneumophila was demonstrated by serological immunocytological and histological techniques in a Wellington man who died of a severe pneumonia. This is the first demonstration of disease produced by this organism in New Zealand. PMID- 6930021 TI - Glomerulonephritis associated with an infected ventriculo-atrial shunt. AB - We present the case of a seven year old girl with a ventriculo-arterial shunt who developed haematuria and the nephrotic syndrome. Renal biopsy showed a diffuse proliferative glomerulonephritis of mesangiocapillary type. Cultures of blood, cerebrospinal fluid and later, the removed shunt, grew Staphylococcus epidermidis. Her renal function subsequently improved following antibiotic therapy and revision of the shunt. PMID- 6930022 TI - Back to it. PMID- 6930023 TI - On being a certifying abortion consultant: an ethical dilemma. PMID- 6930024 TI - Monitoring of drug levels in blood: a challenge to the clinical biochemistry laboratory. PMID- 6930025 TI - Social characteristics of a sample of solo mothers. AB - In 1978 a sample of 158 solo mothers was interviewed by third year psychology students under the supervision of the author to obtain data both on their child rearing practices (for comparison with data obtained the year before from a sample of dual parents) and on their social circumstances. These data indicate that in the case of women who had previously been married, most aspects of their life, with the exception of finance, are now improved. Freedom from conflict and greater independence are cited as the advantages of being a solo parent; loneliness and responsibility are the major disadvantages. Parents and friends are the chief sources of support. PMID- 6930026 TI - A study of mothers' health. AB - The physical and mental health of the mothers of 991 children being examined in phase five of the Dunedin Multidisciplinary Child Development Study was assessed through two questionnaires which were designed to show changes in health status rather than to indicate defined disease. Less than one in five of the mothers gave no positive responses to the questionnaire on physical health and less than two in five gave no positive responses to the questionnaire on psychological health. The general level of health was lower than anticipated. Younger mothers showed more positive responses overall than older mothers and more frequent positive responses correlated significantly with family size and the presence of younger children in the family. It is considered that pressure of child rearing, especially in the larger families and in families with preschool aged children contribute to this lower health status. PMID- 6930027 TI - Health for all by the year 2000. PMID- 6930028 TI - An examination of the relationship between fluoridation of water and cancer mortality in 20 large US cities. AB - A comparison of mortality of 10 US cities with fluoridated water supplies compared with 10 non-fluoridated cities has been used as evidence that artificial fluoridation of drinking water causes cancer and has been widely publicised in New Zealand. Several deficiencies are noted in the analysis used by the investigators in this study and it is shown that appropriate analysis of the data from these cities yields additional evidence for the safety of fluoridation. This finding agrees with that from previous examinations of the same data in spite of the fact that they included an error in the mortality report from one city. PMID- 6930029 TI - Screening for malignant hyperthermia susceptibility. AB - In vitro pharmacological testing of isolated muscle strips surgically removed under general anaesthesia from 10 members of a known MH family enabled identification of three MH positive individuals. Diagnosis of MH susceptibility was based on increased sensitivity to low concentrations of caffeine and the presence of halothane-induced contractures in MH susceptible muscle. Dantrolene sodium 15 mg/l completely prevented halothane-induced contractures in two muscle strips from one of the MH positive cases. The successful anaesthetic management of known MH patients is described, as is the successful management of a hyperthermic episode during recovery in one of the MH positive cases. PMID- 6930030 TI - Three cases of smooth muscle tumours of the small intestine. AB - Three cases of rare primary smooth muscle tumours of the small intestine, two benign and one malignant, are presented. The two benign lesions produced melaena for thirty years and twelve years respectively while remaining undetected by repeated investigation; the third case presented more acutely with obstruction. All three tumours were excised curatively. PMID- 6930031 TI - The influence of maternal factors on placental weight. AB - The influence of maternal factors on placental weight has been studied. Their effect may be partially masked as it was not possible to eliminate the effect of fetal factors. For a narrow range of birthweights placental weight correlates increasingly closely with maternal pregnant weight, non-pregnant weight, and weight-for-height; it correlates more closely with all of these than with the baby's birthweight. Maternal obesity has a significant effect on placental weight independent of the possible fetal effect. Maternal height and weight gain in pregnancy share no such effect. Pregnancy weight gain is a poor indicator of feto placental development. PMID- 6930032 TI - Pain and acupuncture. PMID- 6930036 TI - Tinea imbricata in New Zealanders. PMID- 6930034 TI - What encourages and discourages children to smoke? Knowledge about health hazards and recommendations for health education. AB - A confidential smoking questionnaire was answered by 102 fourth formers and 89 sixth formers at a Dunedin High School. Thirty-nine percent of the sample were smoking (more than half infrequently), 42 percent had tried and given up and 19 percent had never tried a cigarette. Pupils' smoking habits were related to the smoking habits of their friends but not their parents. Most children associated cancer with smoking but only 37 percent associated it with cardiovascular disease and 18 percent gave an incorrect answer or answers. The main reason why children tried their first cigarette was curiosity (57 percent) but the main reason why "some children" take up smoking was to be tough and impress others (71 percent). Boys experimented earlier than girls (mean age boys, 10 years, two months, girls, 11 years, seven months). Children were most discouraged from smoking by the health risk (52 percent), and they thought that the best way to discourage others was to show them the harmful effects (32 percent) and increase health education (27 percent). Since 1961 smoking appears to have declined among European fourth form boys and increased among girls. More Maori or part-Maori pupils smoke than Europeans. The discussion includes suggestions for improving health education. PMID- 6930033 TI - Setting objectives for drug control policy. PMID- 6930035 TI - The milk bottle hand. PMID- 6930037 TI - Changes in nursing education. PMID- 6930038 TI - World Health Day, 1980: smoking or health, the choice is yours. PMID- 6930040 TI - Riverton Hospital Day Ward: a community health project. PMID- 6930039 TI - Effective management and consultation. PMID- 6930041 TI - Standards for nursing--their impact on quality care. PMID- 6930045 TI - Obstetrics and the winds of change. PMID- 6930042 TI - An American family health nurse practitioner. PMID- 6930043 TI - Towards a staffing formula: a staffing system for general obstetric wards. Part 2. PMID- 6930044 TI - The Christchurch diabetes centre education programme. PMID- 6930046 TI - The great mimicker. PMID- 6930047 TI - Primary health care in New Zealand. PMID- 6930048 TI - Quality nursing care for all. PMID- 6930050 TI - Red cross nurse on the Thai-Cambodian borders. PMID- 6930051 TI - Assignment: diabetes mellitis. PMID- 6930049 TI - Night work for nurses--"living upside down". PMID- 6930052 TI - The position and role of the enrolled nurse within the nursing structure of New Zealand. PMID- 6930053 TI - Women in New Zealand. PMID- 6930054 TI - NZNA Conference 1980 Presidential Address. PMID- 6930055 TI - Ostertagiasis survey: summary and discussion. PMID- 6930056 TI - Sheep breed differences in pentobarbitone sleeping-time and response to experimental sporidesmin intoxication. PMID- 6930057 TI - Leptospirosis and other infections of Battus rattus and Rattus norvegicus. PMID- 6930058 TI - Dry-cow therapy for Staphylococcus aureus mastitis. PMID- 6930059 TI - Unnatural selection and survival of the fittest. PMID- 6930062 TI - Lymphosarcoma in a thoroughbred filly. PMID- 6930063 TI - A case of erythremic myelosis in a cat. PMID- 6930060 TI - A survey of bovine infectious keratitis (pinkeye) in beef cattle. PMID- 6930061 TI - Betamethasone for the induction of parturition in dairy cows: a comparison of formulations. PMID- 6930067 TI - Gardner's syndrome with an unusual fibro-osseous lesion of the mandible. AB - A girl with a family history of Gardner's syndrome presented with an actively growing central lesion of the mandible and localized subcutaneous fibrous hyperplasia which required surgical intervention and bone grafting. The importance of this syndrome is the development of intestinal polyposis which become malignant. The presence of dentofacial stigmata and surface tumors should alert the dentist and physician to the possibility of Gardner's syndrome. PMID- 6930065 TI - The interrelationship of dry socket sequelae. PMID- 6930064 TI - Utilization of auxiliaries. PMID- 6930066 TI - A thirty-two year implant retrospect and prospect. PMID- 6930068 TI - The pattern of fractures of the facial skeleton in Kaduna, Nigeria. A survey of 1,447 cases. AB - A survey of 1,447 Nigerian patients with fractures of the facial skeleton is presented. The frequency and etiology of the fractures are described. Patients mainly affected were in the third decade of life. The male:female ratio is strikingly high, and the site distributions of the fractures are recorded and compared with those of other series. The cause of delay in reporting for treatment is examined, and the subsequent sequalae are outlined. Life-endangering injuries occurred in association with facial fractures. The necessity for teamwork between surgical specialists is emphasized. All fractures were treated by simple methods of fixation. PMID- 6930069 TI - Multiple bilateral dens in dente as a factor in the etiology of multiple periapical lesions. AB - A case of multiple bilateral dens in dente of the maxillary anterior region with associated multiple periapical lesions of the maxilla is reported. Examination demonstrated the condition known as dens in dente to be present in all six maxillary anterior teeth. Also noted was a large palatal swelling which was confirmed to be an infected maxillary radicular cyst. The multiplicity, severity, and consequences of the dens in dente as reported in this case may indicate prophylactic restorative therapy. PMID- 6930070 TI - Cuspid gigantism. PMID- 6930073 TI - Eczema herpeticum. PMID- 6930071 TI - Facial neuralgia associated with recurrent herpes simplex. AB - At least seven cases of facial neuralgia associated with recurrent herpes simplex have been reported in the medical literature. This condition has not been reported in the dental literature. A case of facial neuralgia associated with recurrent herpes simplex in a 34-year-old woman at varying intervals over a 20 year period is reported. Tension applied to the commissure on the right side of the patient's mouth during routine dental procedures can cause the neuralgia to develop, and she reports having undergone extraction of the permanent right mandibular first molar at the age of 15, when a similar neuralgia was present. PMID- 6930074 TI - Oral warty dyskeratoma. AB - Warty dyskeratoma (isolated dyskeratosis follicularis) is generally thought of as a cutaneous lesion of the head and neck regions. A small number of cases have been reported in the oral mucosa, usually overlying the alveolar ridge or the palate. The present case exhibits both clinical and histologic features which are consistent with the previously reported cases. PMID- 6930075 TI - Cheilitis glandularis. AB - A case of cheilitis glandularis simplex occuring in a 65-year-old white man is presented. The condition is characterized by an everted lower lip, with enlarged labial salivary glands secreting a clear, thick mucus. A history of sun exposure, dry atrophic lip, and histologic findings of epithelial dysplasia, sclerosed glands, markedly dilated ducts, chronic inflammation, and basophilic degeneration of collagen indicate a solar etiology. Surgical excision by vermilionectomy gave excellent results. A high incidence of severe epithelial dysplasia and squamous cell carcinoma associated with cheilitis glandularis indicate surgery as the treatment of choice. PMID- 6930072 TI - Generalized argyria secondary to chewing photographic film. Report of a case. AB - A case report of generalized argyria found on routine examination and confirmed by history has been reviewed. The condition has been present for the last 16 years and has gone unchanged. A review of argyria is presented, and the importance of other systemic disease entities in patients with skin discoloration is mentioned. PMID- 6930077 TI - Precision measurement control in endodontics. AB - A technique for measurement control in endodontic therapy is presented. The technique, which involves the use of a 10 mm segment of plastic ruler mounted on the end of a mirror handle, eliminates the inaccuracies associated with rubber stops and other devices used for measurement control. It gives the dentist precision control of instrumentation, which is vital to the development of a dentinal matrix at an optimum position. PMID- 6930076 TI - The oral hair: an extremely rare phenomenon. AB - A proven case of true hair occurring naturally in the mouth has been reported only once previously. A second case of this rare anomaly is reported here. In this case a single hair was found at the base of the attached gingiva in the mandibular cuspid region of a 45-year old white man. PMID- 6930079 TI - Nursing in Dhahran, Saudi Arabia. PMID- 6930078 TI - Chondrometaplasia involving the temporomandibular joint. AB - The pathogenesis of chondrometaplasia is discussed and a case of a single loose body in the temporomandibular joint is presented, with radiologic observations, operative findings, and histologic studies. PMID- 6930080 TI - China report--a nursing tour of the People's Republic of China. PMID- 6930081 TI - [Assisted ventilation during an asthmatic attack with the aid of sodium oxybutyrate and pancuronium bromide]. PMID- 6930082 TI - [Fertility in young patients in lasting remission of leukemia and malignant lymphoma treated during puberty]. PMID- 6930083 TI - [Proliferation and maturation of the hematopoietic cells in myelocytic leukemia in the stage of blast crisis]. PMID- 6930087 TI - Stress effects of changing roles and work events on midlife. PMID- 6930084 TI - [Results of joint research on the chemotherapy of acute leukemia]. PMID- 6930086 TI - [Monitoring the patient on assisted ventilation]. PMID- 6930088 TI - Family stress and the physician. PMID- 6930085 TI - [Comparative analysis of immunity in acute leukemia treated according to various chemotherapeutic programs]. PMID- 6930091 TI - Management of suicidal behavior. PMID- 6930090 TI - The magnitude of depression in the community. PMID- 6930092 TI - Some problems facing medical education in the decade ahead. PMID- 6930089 TI - Clinical insights into normal grief. PMID- 6930093 TI - Hip fractures. PMID- 6930094 TI - Life-stress and depression symposium. PMID- 6930095 TI - Life-stress and depression symposium. Introduction. PMID- 6930096 TI - Recent life change stress and psychological depression. PMID- 6930097 TI - [Radiation-induced tibial osteosarcoma developing in a treated myelomatous focus]. PMID- 6930099 TI - Diagnosis of pancreatic disease with special reference to the secretin-CCK test. PMID- 6930100 TI - Standardized data collection system for hemophilias. PMID- 6930098 TI - [Effect of radioprotective substances on the antiheparin activity of platelet free plasma of rats subjected to whole-body irradiation]. PMID- 6930101 TI - Monocyte in vitro function in systemic lupus erythematosus (SLE). III. Bactericidal activity in presence of SLE-sera. AB - The bactericidal activity of normal monocytes in the presence of serum from 14 patients with SLE was studied with a modification of the Maaloe technique. The bactericidal activity was impaired in the presence of sera from 8/14 patients. The group with abnormal bacterial killing showed higher clinical activity than did the group with normal killing capacity. Corticosteroid therapy was also more common among patients with reduced killing. A further difference between patients with abnormal and normal killing was that the former had more episodes of infection during a 2-year follow-up period. PMID- 6930102 TI - An unhappy fairy tale. PMID- 6930104 TI - Clinicopathological conference. Forty year old farmer with chills, fever and left upper quadrant calcification. PMID- 6930103 TI - Testicular feminization: patient report and brief review of the literature. PMID- 6930105 TI - Court says lab-made life can be patented. PMID- 6930106 TI - Tumor anorexia: a learned food aversion? AB - Anorexia can occur when a specific diet is associated with a developing illness. The studies reported here show that the decline in food intake which accompanies tumor growth is accompanied by the development of aversions to the specific diet consumed during tumor growth. An immediate elevation in food consumption occurred when a novel diet was introduced. Therefore, the development of learned aversions to the specific diet eaten during tumor growth may be a causal factor in the development of tumor anorexia. PMID- 6930108 TI - [Kleine-Levin syndrome]. PMID- 6930109 TI - Pharmacokinetic considerations for antibiotic treatment of oral infections. PMID- 6930107 TI - Basophilic leukemia. AB - We have described a patient with basophilic leukemia secondary to chronic granulocytic leukemia. Symptoms of hyperhistaminemia were aggravated after chemotherapy with hydroxyurea. Antihistamines (H1 receptor antagonists) controlled many of the symptoms related to hyperhistaminemia. Peptic ulcer disease with hemorrhage, however, is not controlled by H1 receptor blockade and was one of the contributing causes of death. Attempts to purify the leukemic basophils for chemical analysis met with only partial success. In treating patients with basophilic leukemia, supportive therapy for peptic ulcer disease as well as the use of cimetidine for gastric hyper acidity should be used routinely to avoid this potential complication of cytotoxic chemotherapy. PMID- 6930110 TI - Antibiotic therapy in oral surgery. A general survey. PMID- 6930111 TI - Effect of antibiotic treatment on post-operative infections after surgical removal of mandibular third molars. PMID- 6930112 TI - Bacteriology of oral infections. PMID- 6930114 TI - Dental sinusitis. PMID- 6930113 TI - Oral mycoses and antifungal agents. PMID- 6930115 TI - Bacterial endocarditis of oral origin. Pathogenesis and prophylaxis. PMID- 6930116 TI - Antibiotic susceptibility in oral bacteria. PMID- 6930117 TI - Ovarian steroidogenesis in rats following ochratoxin A treatment. PMID- 6930121 TI - [Diagnostic aspects of skeletal orthodontic malocclusion]. PMID- 6930118 TI - A case of acute myeloblastic leukemia with chromosomes showing 46, XY = 11/46, XY, 21q- = 39. AB - Chromosome studies were performed on a 55-year-old male with the clinical diagnosis of acute myeloblastic leukemia. Cytogenetic studies of the bone marrow cells using the quinacrine fluorescence banding and trypsin-Giemsa banding techniques revealed the karyotype 46, XY = 11/46, XY, 21q- = 39. No. 21 chromosome abnormalities in patients with acute myeloblastic leukemia have been amply demonstrated. However, no case of deletion of long arm of chromosome No. 21 has ever been reported in the literature, and it seems that our case is the first report. In view of the rarity of this case, a brief report seems warranted. PMID- 6930119 TI - The effect of bestatin on patients with acute and chronic leukemia and malignant lymphoma. AB - The effects of bestatin was studied in 17 patients with acute and chronic leukemia, and three patients with malignant lymphoma with or without concomitant chemotherapy. Complete remission was obtained in eight patients with acute leukemia and in three patients with malignant lymphoma. Definite effects on both clinical and hematological findings have not been observed in patients with chronic myelogenous leukemia. The PPD and PHA skin reactions increased in about 60 percent of the patients examined. Effects of bestatin on hematological and immunological parameters were obtained at a daily dose of from 30 to 90 mg of bestatin everyday for more than 2 weeks. Bestatin appeared to be useful for the maintenance therapy of hematological malignancies. No side effects due to bestatin were detected. PMID- 6930120 TI - [Prevention in orthodontics]. PMID- 6930122 TI - [Correct timing of the beginning of orthodontic treatment]. PMID- 6930123 TI - [Black spots caused by prolonged exposure to fluoridated drinking water]. PMID- 6930124 TI - [Therapy of advanced cancer of the oral cavity]. PMID- 6930127 TI - [Acute hyperuremic renal insufficiency in untreated chronic myeloid leukemia]. PMID- 6930126 TI - [Black spots caused by prolonged exposure to fluoridated drinking water]. PMID- 6930125 TI - [Cryosurgery, present and future]. PMID- 6930128 TI - [Androgen metabolism in prostate cancer: 3-hydroxysteroid dehydrogenase in relation to the grade of tumor differentiation (author's transl)]. AB - The peripheral zone of the prostate behaves as an androgen target organ, whereas the periurethral glands are under estrogenic stimulation. This anatomical physiological situation explained in the past the endocrine dependence of prostatic carcinoma. Biochemical studies by Prout, however, showed that the response of prostate cancer to contrasexual measures correlates well with the activity of androgen-converting enzymes and with the grade of tumor differentiation. In this study the in vitro activity of 3-hydroxysteroid dehydrogenase (formation of androstanediols from dihydrotestosterone) was assessed in biopsy material of 8 highly differentiated adenocarcinomas and of 14 poorly differentiated tumors by a microassay technique. The results were compared with the enzyme activities obtained earlier from benign prostatic hyperplasia and normal prostatic tissue. In the different cell fractions (cytosol, microsomes) and with various cofactor supplementation, the enzyme activities in highly differentiated tumors strongly resembled those of adenomatous or normal prostate tissues, whereas a relative enzyme deficiency was present in poorly differentiated lesions. The pathophysiological and eventual clinical implications of these findings are discussed. PMID- 6930129 TI - [Treatment of retropharyngeal and paratonsillar abscesses in young children]. PMID- 6930130 TI - Recombinational repair of mitomycin C lesions in phage T4. PMID- 6930132 TI - The new quality assurance standard of the Joint Commission on Accreditation of Hospitals. AB - The Joint Commission on Accreditation of Hospitals (JCAH) has continuously emphasized improvement in the quality of care provided in hospitals as the central purpose of the accreditation process. In striving to assure such improvement, the JCAH has stressed the need for, and the responsibility of, the medical and other professional staffs to provide continuing review and evaluation of patient care. In recent years, quality assessment activities have evolved, proliferated and matured to the extent that they require a purposeful integration if they are to effect sustained improvement in patient care and clinical performance. To assist hospitals in the coordination or integration of quality assessment activities, the Board of Commissioners of the JCAH has approved an important new quality assurance standard. Significant requirements of the new standard are a comprehensive quality assurance program, a written plan, a problem focused approach to the review and evaluation of patient care and clinical performance, an annual reassessment of the program, and an improvement in patient care or clinical performance. The new standard reflects the JCAH belief that an integrated, problem-focused approach to quality assurance will significantly improve the quality of care provided throughout a hospital. Such an approach recognizes the interdependence of hospital departments and services in the provision of patient care, and, therefore, requires a purposeful integration or coordination of quality assessment data and activities. Consequently, quality assessment data may be utilized effectively and efficiently, and many potentially useless or duplicative quality assessment activities can be eliminated. The new standard affords hospitals considerable flexibility in the manner in which they implement and administer the program and encourages innovation. PMID- 6930131 TI - [Immunotherapy of acute leukemias--present status and perspectives]. PMID- 6930134 TI - [Preparation of the crown stump]. PMID- 6930133 TI - Current therapy of childhood osteosarcoma and Ewing's sarcoma. PMID- 6930135 TI - [Systematized work in crown stump preparation. The concept of 4 as a basic principle]. PMID- 6930136 TI - [Instrument combinations for crown stump preparation. Basic concepts and principles]. PMID- 6930137 TI - [Biological aspects of cavity and crown stump preparation]. PMID- 6930138 TI - [Rationalization through a new treatment record. Results of a field trial (part II)]. PMID- 6930139 TI - [The dentist and informed consent]. PMID- 6930140 TI - [Emergencies in the dental practice--recognition and treatment]. PMID- 6930141 TI - ["Return to the solidly built, average achievement plateau"]. PMID- 6930142 TI - [Responsible coordination of training for dental health]. PMID- 6930144 TI - Role of androgens in hCG-induced ovulation in PMSG-primed immature rats. PMID- 6930145 TI - The stability of the hip in children. A radiological study of the results of muscle surgery in cerebral palsy. PMID- 6930143 TI - [On the diagnosis of bone tumours. II. Nucleic acid metabolites in urine of patients with osteogenic and Ewing's sarcoma and osteoporosis (author's transl)]. PMID- 6930146 TI - The amphetamine addicted mother and her child. PMID- 6930147 TI - Osteogenic sarcoma of the breast. Report of a case. AB - The clinical, mammographical, cytological and histological features of a mammary osteogenic sarcoma are reported. The tumor, which was removed by only local excision, had suddenly appeared in the same breast from which previously an intraductal papilloma had been removed. Nearly three years after the operation there is no indication of recurrence. PMID- 6930148 TI - An established human cell line derived from a malignant mediastinal teratoma. AB - An established cell line derived from a human malignant mediastinal teratoma is described. The cell line was composed of slightly atypical fibroblast cells with a population-doubling time of 24 h at the exponential growth phase. The reason why the emerging cell line became fibroblastic although other tissues were present in the original tumor may be that fibroblasts so readily grow in culture. Chromosome banding showed a hypertriploid stemline number, S = 78. Almost all of the analysed karyotypes had seven markers in common. Eleven other markers, occurring at low frequency, were also detected. The origin of all markers except one could be deduced. PMID- 6930150 TI - Azathioprine and subacute myelomonocytic leukemia. AB - The occurrence of subacute myelomonocytic leukemia is reported in a patient who had been treated with azathioprine for six years because of systemic lupus erythematosus. A review of the literature yielded 16 additional patients with non lymphocytic leukemia after the use of azathioprine. PMID- 6930149 TI - Human power at subnormal body temperatures. PMID- 6930151 TI - Predicting response to combination chemotherapy in acute myeloblastic leukemia--- a way to individualize treatment. AB - Cytostatics are toxic, and individual variations in drug metabolism large. Therefore the possibility to predict which cytostatic combination should be abandoned because it will not lead to a remission was studied in 58 leukemia patients. A simple following of changes in white blood cell, platelet and blast cell numbers in peripheral blood (combined into so-called chemotherapy points) makes it possible to predict which patients in the presenting phase of AML will achieve remission, but this was possible neither in the relapse phase of AML, nor in promyelocytic or monocytic leukemias. All 27 patients in the initial phase of AML, who later were to achieve remission, had less than 12 chemotherapy points, and 9 of 11 patients who did not achieve remission had over 13 points. Therefore the cytostatic combination should be changed in patients who, after two courses of treatment, have over 13 points. PMID- 6930152 TI - Correlation between prognostic factors and blood variables in osteosarcoma. AB - Prognostic factors and the blood chemistry were analyzed prior to treatment in 33 consecutive patients with primary osteosarcoma. The only variables of blood chemistry with values outside the normal range were alkaline phosphatase and ESR, which were increased. There was a correlation between certain prognostic factors and between some of these and a number of the blood variables. The degree of malignancy tended to be lower in the female than in the male patients. Distally located tumors tended to be smaller and were assessed with a less marked effect on the blood variables than those located proximally. PMID- 6930154 TI - Lumbar leptomeningeal and radicular reactions after the subarachnoid injection of water-soluble contrast media, meglumine iocarmate (dimer-Xr) and metrizamide (amipaquer). An experimental study in the pig. PMID- 6930153 TI - Low milk fat syndrome in Swedish dairy cows. Field and experimental studies with special reference to the rumen microbiota. PMID- 6930156 TI - Outcome of hepatitis in children with acute leukemia. AB - The cases of 31 children with acute leukemia and concurrent hepatitis were evaluated for the outcome of their hepatitis. Thirteen of these children had hepatitis B and 18 children had a non-B hepatitis. Chronic hepatitis developed in more than half of the children with acute hepatitis, with the majority of cases being of the chronic, active type. A majority of these children had received at least one blood transfusion in the preceding year. No relationship was seen between the development of chronicity of the liver disease and the management of the acute hepatitis or the state of underlying disease. With the potential for a cure for acute leukemia increasing, a method of reducing the sequelae of hepatitis in children with leukemia is needed. PMID- 6930155 TI - Pathological lesions in swine at slaughter. III. Inter-relationship between pathological lesions, and between pathological lesions and 1) carcass quality and 2) carcass weight. PMID- 6930159 TI - Coexistent chronic myeloid leukemia and IgA monoclonal gammopathy: report of a case and review of the literature. AB - The coexistence of Philadelphia negative chronic granulocytic leukemia (CGL) of the neutrophilic type and IgA monoclonal gammopathy is reported in a patient. The possible relation between the two proliferative processes is discussed in the light of current knowledge on the pluripotent stem cell and the clonal origin of CGL. PMID- 6930163 TI - Canine root movement: an evaluation of root springs. AB - An analysis of the mechanics required for distal movement of canine roots is presented and, on the basis of this analysis, a specific clinical approach is outlined. Three different root spring designs were tested for their ability to meet the previously determined requirements. The only spring that approached the established requirements was spring A-2. Spring types B and C did not meet the established requirements. Angular activations in excess of 20 degrees in 0.018 by 0.025 inch stainless steel wire without benefit of a loop resulted in permanent deformation of the appliance. PMID- 6930157 TI - Exclusions and attributions of paternity: practical experiences of forensic genetics and statistics. AB - The Swedish State Institute for Blood Group Serology is a central government laboratory handling all blood typing in paternity cases in Sweden, each year testing 1,500-2,000 cases using about 13 polymorphisms. Of the accused men, 35% 40% are nonfathers, but in one-man cases (about 78% of all cases), approximately 75% are the true fathers. Exclusions appear to be distributed as expected from allele frequencies, and the paternity probability of nonexcluded men is assessed with a Bayesian approach. Some cases are retested in extended investigations which raise theoretical exclusion capability from about 87% to about 99%. Both the results of extended investigations and the theoretical consideration of the distribution of paternity probabilities support the use of such positive statistical evidence for the attribution of paternity. PMID- 6930158 TI - Expected and observed proportion of subjects excluded from paternity by blood phenotypes of a child and its mother in a sample of 171 families. AB - The proportion of exclusion for a given mother-child pair is the proportion of males excluded from the paternity of this child of a known mother and may be calculated given both the child's and mother's phenotypes and the population gene frequencies. Its expected value in the population is equal to the probability of exclusion, which expresses a laboratory's capability to exclude from paternity nonbiological fathers.In a sample of 171 families examined for 20 genetic systems at the National Blood Group Reference Laboratory, 25 exclusions of putative fathers were detected. The ranking by efficiency of the systems used in these exclusions fits the "expectation of their efficiency," and the average proportion of males excluded by the child's and mother's phenotypes is not different from the expected proportion. Additionally, the repetition of exclusions in an incompatible putative father-mother-child trio is not dependent on the overall proportion of males excluded by the mother and the child, but rather on some high values of the proportion of excluded men in some specific systems.Here, formulas and some factors modifying these parameters as well as a more efficient sequence of examinations to exclude paternity than has previously been used are given. Using this sequence, laboratories which carry out several analyses per day can work by levels of five examinations at a time, done in a particular order, to obtain a rather rapid exclusion of certain families. PMID- 6930160 TI - Space, time, and space-time in craniofacial growth. PMID- 6930161 TI - Modular intermaxillary fixation for surgical orthodontics. AB - With the increased amount of orthognathic surgery being performed by orthodontists and oral-maxillofacial surgeons, more efficient treatment techniques are being perfected. Modular intermaxillary fixation has been developed to help the orthodontist prepare his patient for surgery and provide the surgeon with the stable fixation needed for proper healing. It is efficient, saves chair time, is comfortable and esthetic, and is well accepted by patients. Modular intermaxillary fixation has been evaluated for more than a year, with good results in correcting mandibular skeletal dysplasias in all three planes of space. PMID- 6930162 TI - Gingival tissue reactions to orthodontic closure of extraction sites. Histologic and histochemical studies. AB - The formation of a hyperplastic gingival tissue with invagination was observed in the extraction areas in seven patients aged 12 to 17 years who, after extraction of the maxillary first premolars, were undergoing orthodontic treatment with an edgewise appliance. This tissue was excised when about 2 mm. of the space remained to be closed. Histologic and histochemical analyses of the biopsy areas demonstrated hyperplasia and increased metabolism in the invaginated epithelium as well as increased production of glucose aminoglycans in the surrounding connective tissue. Loss of collagen was noted in the same regions. There was evidence of bone remodeling rather than only bone resorption in the biopsy area. It was concluded that stimulation from the orthodontic forces was responsible for the hyperplastic tissue reaction and that the increased amounts of glucose aminoglycans may be responsible for possible relapses. PMID- 6930164 TI - Predicting the "Wits" appraisal from the ANB angle. AB - The ANB and "Wits" values of fifty patients were correlated to see how accurately one can predict the "Wits" value, given the ANB measurement. There is no correlation between these two values when the "Wits" measurement is negative. In our study, when the positive ANB measurement was less than 4 degrees, the "Wits" values could be either positive or negative. When the ANB angle was between 4 and 8 degrees, all "Wits" values were positive. When both the "Wits values were positive and the ANB values ranged between 1 and 8 degrees, we could predict the "Wits" measurement with a 38 percent accuracy. If the ANB range was narrowed to 4 to 8 degrees, all "Wits" values were positive and we could predict them 28 percent of the time. Both these figures are statistically significant but clinically irrelevant. Further studies are needed to determine the exact nature of these interrelationships. PMID- 6930166 TI - Orthodontics and craniofacial orthopedics. PMID- 6930165 TI - Activity of the temporal and masseter muscles in class II, division 1 malocclusions. An electromyographic investigation. AB - A quantitative analysis of EMG activity in the masticatory muscles was performed in homogeneous groups of boys with Class II, Division 1 malocclusion and normal occlusion. Integrated EMG recordings from the temporal and masseter muscles were analyzed during maximal biting in the intercuspal position (centric occlusion) and during the chewing of peanuts. The results of the investigation revealed the following: (1) During maximal biting in intercuspal position the boys with Class II malocclusion exhibited less EMG activity in the masseter and temporal muscles than the boys with normal occlusion. In the Class II boys the reduction in EMG activity was most apparent for the masseter muscle. (2) During chewing the Class II subjects showed less EMG activity in the masseter muscle than the normal occlusion subjects. For the temporal muscle, no differences were found between the two occlusion groups. (3) High positive correlations were found between the EMG activity during maximal biting and chewing for both muscles in the two occlusion groups. The impaired muscle activity found in the Class II cases may be attributed to a diverging dentofacial morphology and unstable occlusal contact conditions. PMID- 6930168 TI - American Board of Orthodontics. The change in American Board of Orthodontics Phase III requirements. PMID- 6930169 TI - An individual compass for extraction. PMID- 6930167 TI - Early fracture of the mandibular condyles: frequently an unsuspected cause of growth disturbances. AB - Experience with patients referred to the Dentofacial Clinic at the University of North Carolina indicates that previous fracture of the mandibular condylar process may be involved in 5 to 10 percent of all severe mandibular deficiency or asymmetry problems. Since these fractures often go undiagnosed and since three fourths of the children with fractures have no growth deficits, the incidence of condylar fractures probably is much higher than commonly thought. Management of fracture patients immediately following the accident, during the postinjury stages of mandibular growth, and at completion or near-completion of growth is discussed. PMID- 6930171 TI - Computer-aided head film analysis: the University of California San Francisco method. AB - Computer technology is already assuming an important role in the management of orthodontic practices. The next 10 years are likely to see expansion in computer usage into the areas of diagnosis, treatment planning, and treatment-record keeping. In the areas of diagnosis and treatment planning, one of the first problems to be attacked will be the automation of head film analysis. The problems of constructing computer-aided systems for this purpose are considered herein in the light of the authors' 10 years of experience in developing a similar system for research purposes. The need for building in methods for automatic detection and correction of gross errors is discussed and the authors' method for doing so is presented. The construction of a rudimentary machine readable data base for research and clinical purposes is described. PMID- 6930170 TI - A clinical evaluation of the differential force concept as applied to the edgewise bracket. AB - When the Siamese edgewise bracket with continuous arch wires is used, it does not always follow that with 100 to 150 Gm. of applied force only the canine and not the buccal segment or anchor unit will move. Conversely, it does not always follow that with 400 to 500 Gm. of applied force only the buccal segment or anchor unit will move forward and the canine will not move. With the sliding mechanics of this study, the percentage of greater rates of tooth movement happening coincident with greater forces was found to be 0.86. With the edgewise bracket and sliding mechanics, the curves showed that, in general, reciprocal forces cause reciprocal tooth movement with varying and relative rates of space closure. Subjectively, no relationship was found between pain and increased forces; that is, pain in this study was found just as often on the side with 100 to 150 Gm. of applied force as on the side with 400 to 500 Gm. of applied force. This is not to say that there is not more tissue damage found with the use of heavier forces. PMID- 6930172 TI - Alterations in the facial skeleton of the guinea pig following a lesion of the trigeminal motor nucleus. AB - In thirty-three of sixty-six guinea pigs of the Topeka strain small, unilateral, electrolytic lesions were produced in the motor nucleus of the trigeminal nerve. Unoperated animals and the side contralateral to the muscle paralysis served as controls. Lesions were created when animals were 15 days or 75 days of age, and the animals were killed 15, 30, 45, or 60 days postoperatively. Each animal was subjected to dry skull preparations or radiographic and histologic techniques. Alterations in craniofacial form were noted in both the growing animals and the animals with little growth remaining. Alterations in form and function included paralysis and atrophy of the muscles of mastication on the lesion side, hypereruption of teeth, and reduction in growth of facial bones on the lesion side. Remodeling changes were evident in the glenoid fossa, the condylar process, and the coronoid process on the operated side but were not apparent in the contralateral control or the unoperated control animal. PMID- 6930176 TI - Psychology: the leading edge. PMID- 6930174 TI - Correlations between orofacial muscle activity and craniofacial morphology in a sample of control and anterior open-bite subjects. AB - In order to investigate the correlations between genioglossus, masseter, and orbicularis oris muscle activity and craniofacial morphology, an electromyographic and cephalometric analysis was undertaken on a series of twenty four human subjects. The activity from the muscles was recorded during voluntary opening movements of the mandible monitored by an electronic transducer. A computer-based method was devised to calculate the threshold incisor-separation position corresponding to a 20 percent increase in base line muscle activity for each of the muscles. In addition, twenty-seven anatmoic points were digitized from lateral head films, and a computer-based cephalometric analysis was completed for each subject. A number of significant correlations were found between the threshold muscle values and the thirty-one linear and angular morphologic variables. Low threshold values for the genioglossus muscle were correlated with negative overbites, undererupted maxillary and mandibular incisors, and low total face heights. Low threshold values for the masseter muscle were also associated with low overbite measurements. In contrast, orbicularis oris muscle thresholds did not appear to be correlated with any of the craniofacial variables measured. This interdependence of tongue and jaw muscle activity and facial morphology suggests a contribution of the musculature to the development and/or maintenance of the dentition. PMID- 6930173 TI - A comparison of plain versus multilooped arch wires in stage I of Begg therapy. AB - In order to overcome the reportedly undesirable side effects of using multilooped arch wires in initial stages of Begg mechanotherapy, a clinical study was conducted in which treatment procedure was modified for the mandibular arch in one group of patients, who received nonlooped or plain mandibular arch wires. This group was closely matched with respect to age, sex, severity of malocclusion, and particularly the amount of anterior mandibular crowding with a group of patients who received multilooped arch wires designed very closely according to the classically prescribed methods. Comparison of the two groups by means of cephalometric measurements of the mandibular incisors at the end of Stage I of treatment demonstrated that the IMPA increased significantly more (p = 0.01) in the multilooped arch wire group. The over-all treatment time was not significantly different in the two groups, although it took longer to resolve the anterior mandibular crowding when plain wires were used. On the basis of this study, it would appear that the use of plain rather than multilooped arch wires in the mandibular arch deserves a favorable consideration in early Begg therapy. PMID- 6930177 TI - The regulation of pain. PMID- 6930175 TI - Some blood genetic markers of selected tribes in Western Saudi Arabia. AB - A total of 292 randomly selected subjects belonging to two indigenous Arab tribes (Harbi and Ghamid) and two immigrant tribes (Mograbi and Mowallad), residents in Western Saudi Arabia, have been tested for genetic variants of six blood groups, four serum proteins, and five red cell enzyme systems. The distribution of the polymorphic systems was different between indigenous and immigrant tribes, and the present Arab population shows a considerable degree of admixture from the surrounding countries, in particular Africa. PMID- 6930180 TI - Applications of photochemistry in probing biological targets. PMID- 6930179 TI - The behavioral mechanism to explain abnormal behavior. PMID- 6930178 TI - The evoked magnetic field of the human brain. PMID- 6930181 TI - Photosensitive steroids as probes of estrogen receptor sites. PMID- 6930183 TI - Use of NAP-taurine as a photoaffinity probe for the human erythrocyte anion exchange system. PMID- 6930182 TI - Use of lipophilic photoactivatable reagents to identify the lipid-embedded domains of membrane proteins. PMID- 6930184 TI - Photoaffinity labeling of anion transport components in hepatocyte plasma membranes. PMID- 6930186 TI - Topology of the ribosomal binding sites for tRNA as revealed by photoaffinity labeling. PMID- 6930187 TI - Photo-cross-linking studies of nucleic acid structure. PMID- 6930185 TI - Photolabile antibiotics as probes of ribosomal structure and function. AB - In summary, our studies have resulted in the development of new reagents and synthetic procedures for the introduction of both radioactivity and photolability into antibiotics; have provided examples of how PAGE analysis can be used to conveniently test various aspects of photoaffinity labeling of complex receptors, such as the ribosome; have revealed examples of unexpected photoreactivity, as in the case of puromycin; and have provided strong evidence regarding the three dimensional location of the peptidyl transferase center and the site of that interaction of the 3' and of aminoacyl-tRNA with the 30S subunit. Work that is now in progress should provide similar detailed information regarding other functional sites in the ribosome.